LOCUS       DAMJWC010000001       139050 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMJWC010000001 DAMJWC010000000
VERSION     DAMJWC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 139050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 139050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..139050
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.001"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(112..1713)
                     /locus_tag="PC503_000001"
     CDS             complement(112..1713)
                     /locus_tag="PC503_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2526029.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCYGKIITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1824..2501)
                     /locus_tag="PC503_000002"
     CDS             complement(1824..2501)
                     /locus_tag="PC503_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526030.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2514..3209)
                     /locus_tag="PC503_000003"
     CDS             complement(2514..3209)
                     /locus_tag="PC503_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2526031.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3261..4460)
                     /locus_tag="PC503_000004"
     CDS             complement(3261..4460)
                     /locus_tag="PC503_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2526032.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4721..6766)
                     /locus_tag="PC503_000005"
     CDS             complement(4721..6766)
                     /locus_tag="PC503_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526033.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7177..7986)
                     /locus_tag="PC503_000006"
     CDS             complement(7177..7986)
                     /locus_tag="PC503_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2526034.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8070..8603)
                     /locus_tag="PC503_000007"
     CDS             complement(8070..8603)
                     /locus_tag="PC503_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2526035.1"
                     /translation="MSGAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8753..10102)
                     /locus_tag="PC503_000008"
     CDS             complement(8753..10102)
                     /locus_tag="PC503_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2526036.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSITSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10114..11496)
                     /locus_tag="PC503_000009"
     CDS             complement(10114..11496)
                     /locus_tag="PC503_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2526037.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIESGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11740..12954
                     /locus_tag="PC503_000010"
     CDS             11740..12954
                     /locus_tag="PC503_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2526038.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13131..15044
                     /locus_tag="PC503_000011"
     CDS             13131..15044
                     /locus_tag="PC503_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526039.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15315..16289
                     /locus_tag="PC503_000012"
     CDS             15315..16289
                     /locus_tag="PC503_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2526040.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16310..16585
                     /locus_tag="PC503_000013"
     CDS             16310..16585
                     /locus_tag="PC503_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2526041.1"
                     /translation="MNAIIHANEKDNLVTCVRPLIKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16598..17761
                     /locus_tag="PC503_000014"
     CDS             16598..17761
                     /locus_tag="PC503_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2526042.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VNYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18098..20377
                     /locus_tag="PC503_000015"
     CDS             18098..20377
                     /locus_tag="PC503_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2526043.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20472..21812)
                     /locus_tag="PC503_000016"
     CDS             complement(20472..21812)
                     /locus_tag="PC503_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2526044.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(21824..22606)
                     /locus_tag="PC503_000017"
     CDS             complement(21824..22606)
                     /locus_tag="PC503_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526045.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22621..23643)
                     /locus_tag="PC503_000018"
     CDS             complement(22621..23643)
                     /locus_tag="PC503_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2526046.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23649..24662)
                     /locus_tag="PC503_000019"
     CDS             complement(23649..24662)
                     /locus_tag="PC503_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2526047.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24790..25728)
                     /locus_tag="PC503_000020"
     CDS             complement(24790..25728)
                     /locus_tag="PC503_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2526048.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLAKPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            25998..26462
                     /locus_tag="PC503_000021"
     CDS             25998..26462
                     /locus_tag="PC503_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526049.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26574..26891)
                     /locus_tag="PC503_000022"
     CDS             complement(26574..26891)
                     /locus_tag="PC503_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2526050.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(26904..27635)
                     /gene="chbG"
                     /locus_tag="PC503_000023"
     CDS             complement(26904..27635)
                     /gene="chbG"
                     /locus_tag="PC503_000023"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF2526051.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLLSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27661..28971)
                     /locus_tag="PC503_000024"
     CDS             complement(27661..28971)
                     /locus_tag="PC503_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2526052.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29068..30381)
                     /locus_tag="PC503_000025"
     CDS             complement(29068..30381)
                     /locus_tag="PC503_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526053.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30403..30714)
                     /locus_tag="PC503_000026"
     CDS             complement(30403..30714)
                     /locus_tag="PC503_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526054.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(30914..31618)
                     /locus_tag="PC503_000027"
     CDS             complement(30914..31618)
                     /locus_tag="PC503_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2526055.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDVRVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31709..33070)
                     /locus_tag="PC503_000028"
     CDS             complement(31709..33070)
                     /locus_tag="PC503_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2526056.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33569..34723
                     /locus_tag="PC503_000029"
     CDS             33569..34723
                     /locus_tag="PC503_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2526057.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(34805..36523)
                     /locus_tag="PC503_000030"
     CDS             complement(34805..36523)
                     /locus_tag="PC503_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2526058.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAASLAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(36528..37409)
                     /locus_tag="PC503_000031"
                     /pseudo
     CDS             complement(36528..37409)
                     /locus_tag="PC503_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     regulatory      37686..37783
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            37838..38014
                     /locus_tag="PC503_000032"
     CDS             37838..38014
                     /locus_tag="PC503_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526059.1"
                     /translation="MFRDKMDKCTHVLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     gene            38121..38321
                     /locus_tag="PC503_000033"
     CDS             38121..38321
                     /locus_tag="PC503_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526060.1"
                     /translation="MCFKTYILKRVVNNKQLEITRSFELDNLICTATEILKDDEIDLI
                     IIDEKNSIVWRNEKSTPQQENA"
     gene            complement(38500..39372)
                     /locus_tag="PC503_000034"
     CDS             complement(38500..39372)
                     /locus_tag="PC503_000034"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526061.1"
                     /translation="MSNINNKNKSWIEKHKILTIFISVIAILIICIGLPSLINRVLYW
                     DIKTHNSTDGEWLSFWGSFLGGIFGGLATLGAILITREMAKKDNEELKESISMEREPK
                     VIPIKKNAYLYKTYGSPCMFNEIKTSSEVPRCSDIIELTLVNVGKEAAIQIEVFWEKP
                     LNIVKTEYLTDDDLEVCNNFFDEFDENENIKVEKEYISSLQEVEIGLNAYTEMYIREL
                     SSKLIDNFRENNEDGIYIRKNIKAGTINIKCKNIYDKSYNKSYDMEISIFEMDRSKEL
                     YTINIDFNLIEDEG"
     gene            complement(39569..40153)
                     /locus_tag="PC503_000035"
     CDS             complement(39569..40153)
                     /locus_tag="PC503_000035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526062.1"
                     /translation="MKGEYNKEKEKVIKFNSNKDKSKINKYTDYYNTLNSTLMEKNKC
                     IGDNWFLATTSEEVGNMNEEEKRILETEKRILETEKRVHQNNKEVKESIDKQFNDIKG
                     IFKEYKNDLDKDRIELKNDLARERIELKSDLKEAINEHKKVTEKDVSEIKNSIKGIED
                     RIDSTNKWIIALCITTIIGIATMAITIGISIWPK"
     gene            complement(40156..40647)
                     /locus_tag="PC503_000036"
     CDS             complement(40156..40647)
                     /locus_tag="PC503_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526063.1"
                     /translation="MAYENGTNLVAYFPNCIKKYEKDNKIFEKTILLLNLYMQMPTWP
                     HCIHEFKAKANEILGEDPEFIGEYGIKLKDFYNEGENVNISQNFKNDLYTFSNSTYDI
                     LDNSYIQRINPIGLYSISSLARENDFILKLFRNDKKSLELELSKSEIQSIIEHLESMI
                     EEE"
     gene            complement(40897..41703)
                     /locus_tag="PC503_000037"
     CDS             complement(40897..41703)
                     /locus_tag="PC503_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2526064.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCKIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNSKLSTVFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKTIDNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTENLYVVGGGACEKISSMTKERYTMIKGNDRFDTLYKALEFINK"
     gene            complement(41703..41960)
                     /locus_tag="PC503_000038"
     CDS             complement(41703..41960)
                     /locus_tag="PC503_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2526065.1"
                     /translation="MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            complement(41980..42210)
                     /locus_tag="PC503_000039"
     CDS             complement(41980..42210)
                     /locus_tag="PC503_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HDF2526066.1"
                     /translation="MNEELVKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLVGFFIFAIQKGIF"
     gene            complement(42251..42433)
                     /locus_tag="PC503_000040"
     CDS             complement(42251..42433)
                     /locus_tag="PC503_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526067.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRMAVEN
                     YIIEHSEVVEGAELTK"
     gene            complement(42433..42726)
                     /locus_tag="PC503_000041"
     CDS             complement(42433..42726)
                     /locus_tag="PC503_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526068.1"
                     /translation="MERGNRIICDQTGKILLQTGEATGDILEHDEITELHFVDIPYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQILLNENEKVGGIL"
     gene            complement(42747..44423)
                     /locus_tag="PC503_000042"
     CDS             complement(42747..44423)
                     /locus_tag="PC503_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526069.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWYTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQIMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYYPYTGGAGGGLAGGTGYSANDRHR
                     PGGTQYQGGIGRVSTENGSFGKGCSAKDSTGEGGGGGWFGGAGMNGAGAGGGGSGYVL
                     TKDSYKPTGYTPTSEYYFDNVVMESGGNTAGAYGYAKITLLQALPFLTVSSYNSITAT
                     FKADHTDPTLLTKIEYFIDDVLKETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNA
                     TAEKVLSISKNIMPLPEDVNLQDISSKLIEVNAGFKTGKTSIINTLALKNIEANLNNT
                     LVELSEKIKTGFDSSDATAEQLQNQITNLNNQLSQRKRWAKGTYTFTQSDYENFYSRY
                     SSAENYAKSLTVPINLNFIPSLVIVEKLCFYGNGYTVNFYAINNLNQLASVGRVPKSS
                     GEYRFCAFMFVKTITSKEFSLYTYRDEYTDSSSVVYRCKVGESFTWYAYE"
     gene            complement(44438..45463)
                     /locus_tag="PC503_000043"
     CDS             complement(44438..45463)
                     /locus_tag="PC503_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2526070.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSNVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKIELTSNIETAKTELNTRIDTENEKQNIKIDNIIAGGVNVSHTHIIE
                     VADWTLNNETNMYEVTINHPLLTKRILIALYDEIGEALTPNARAIDDNSILVRNEENI
                     KMYVYLINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFLNLEEKVNGGISSIATSV
                     NELITYC"
     gene            complement(45475..46092)
                     /locus_tag="PC503_000044"
     CDS             complement(45475..46092)
                     /locus_tag="PC503_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2526071.1"
                     /translation="MDKEINLINYLPQVLQDKEEYIKVFNAENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSINPKSNETLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNSTYNIHLESDARNQDWFEEVHSFVSSIKPCNMSLDYTRVLVSKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDILTGNGVGYQEVTIF"
     gene            complement(46085..47134)
                     /locus_tag="PC503_000045"
     CDS             complement(46085..47134)
                     /locus_tag="PC503_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2526072.1"
                     /translation="MFEFMTFENIIKRMLDSVPSTLDKREGSIIYNALAPVAIELSET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISECIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWNGGGTVKLVIINSNFKV
                     PSSDLVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWEN
                     IKLIAEEVIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMTNDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            complement(47134..47553)
                     /locus_tag="PC503_000046"
     CDS             complement(47134..47553)
                     /locus_tag="PC503_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2526073.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     IENVDNFEFENIKGKVNCKFMVHTKYGNIKAERVVSV"
     gene            complement(47558..47818)
                     /locus_tag="PC503_000047"
     CDS             complement(47558..47818)
                     /locus_tag="PC503_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF2526074.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMQIAFGTIESVNPLVVKIEQKA
                     SFEESFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            complement(47832..49805)
                     /locus_tag="PC503_000048"
     CDS             complement(47832..49805)
                     /locus_tag="PC503_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2526075.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDEFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGSIFVKYSNAYK
                     VNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFGSVDEGIKRGISNLSRNYIHMG
                     RKTLESIRDKYAPLYDSPLNKHWVPGVNKFYKQITGNAYSSNSAGTGVRSNEEAEKNL
                     KDITYQVQNSNNANTSTNNNSKVNKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAF
                     KRGAGINLKRVSADQSNDSRGKLLCNINDVKAGDLVFFAYNQGKGNVHHVGLCIGNDK
                     FIHSPNTGDVVKISSLSGRQKQKHDFARARRFF"
     gene            complement(49798..50499)
                     /locus_tag="PC503_000049"
     CDS             complement(49798..50499)
                     /locus_tag="PC503_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2526076.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDVKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPTPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            complement(50515..52857)
                     /locus_tag="PC503_000050"
     CDS             complement(50515..52857)
                     /locus_tag="PC503_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDF2526077.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKFKDTFDISKIAEKAKKDLGLDDLWDKKYGLGD
                     GLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            complement(52924..53715)
                     /locus_tag="PC503_000051"
     CDS             complement(52924..53715)
                     /locus_tag="PC503_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF2526078.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            complement(53783..53977)
                     /locus_tag="PC503_000052"
     CDS             complement(53783..53977)
                     /locus_tag="PC503_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526079.1"
                     /translation="MYEGDYDSNIAHYCLHKFKWKPHEYMDLPVDEKAFVAASIDIKV
                     EEEKEEAKKADKDAKRGRRR"
     gene            complement(53977..54417)
                     /locus_tag="PC503_000053"
     CDS             complement(53977..54417)
                     /locus_tag="PC503_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2526080.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPILNKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            complement(54422..54679)
                     /locus_tag="PC503_000054"
     CDS             complement(54422..54679)
                     /locus_tag="PC503_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526081.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            complement(54732..55202)
                     /locus_tag="PC503_000055"
     CDS             complement(54732..55202)
                     /locus_tag="PC503_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2526082.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            complement(55224..56534)
                     /locus_tag="PC503_000056"
     CDS             complement(55224..56534)
                     /locus_tag="PC503_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDF2526083.1"
                     /translation="MALGGGTFVTQNKVLPGSYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIAIAKYSGIRGNDLKIIVTTNIDDNAKFDVVTLLDNKKVDIQVAKVITDLQDNDYI
                     TWKKDATLEATAGLTFTNGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVGVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            complement(56535..56711)
                     /locus_tag="PC503_000057"
     CDS             complement(56535..56711)
                     /locus_tag="PC503_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526084.1"
                     /translation="MSKTLNKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEKIINNFMKGVS"
     gene            complement(56704..57141)
                     /locus_tag="PC503_000058"
     CDS             complement(56704..57141)
                     /locus_tag="PC503_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526085.1"
                     /translation="MLNNIIDGISIKLDKSFGNEYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRELKKNSFDVHYFPKSNDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKSNDTDKMDTVELFGGLKRGDNFE"
     gene            complement(57134..57559)
                     /locus_tag="PC503_000059"
     CDS             complement(57134..57559)
                     /locus_tag="PC503_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2526086.1"
                     /translation="MARWGSVDFREFKRACRRMEKFTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLREGWSGIAYARSLPVYKSGNNYIIEVINPTEYASYVEFGHRTKNG
                     KGWVKGQHFLTISEMELQGQIDKIIEKKLLILLKGVFDA"
     gene            complement(57559..57906)
                     /locus_tag="PC503_000060"
     CDS             complement(57559..57906)
                     /locus_tag="PC503_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526087.1"
                     /translation="MMDKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNITSTTDEKVAKLVQTIKLFISPNINIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELLKDKA"
     gene            complement(57906..58256)
                     /locus_tag="PC503_000061"
     CDS             complement(57906..58256)
                     /locus_tag="PC503_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDF2526088.1"
                     /translation="MEYKIIKIKRLLGLNESDSSKDTILEFILEDVEEIVKNYCNVPT
                     IPEQLNSTILRMAIEMYKNESLGSEDVALGSISSISEGDTSISYRSSASEFKESLLKD
                     YKAQLNRYRKIRWK"
     gene            complement(58259..59317)
                     /locus_tag="PC503_000062"
     CDS             complement(58259..59317)
                     /locus_tag="PC503_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coat protein"
                     /protein_id="HDF2526089.1"
                     /translation="MNKNKSLKMNIQLLAGNEGGTKLSDIIVPSLFNPYVINRTMEKS
                     ALLQSGIITNNSEFDKLASQASPLVNMPFFEDLTGESEQIIEDVDLQNNKITSNADVA
                     VIMRRAKMWSATDLSAALAGKDPAGAIAELVSGFWARDMQKELIAILKGVFGTTKAVG
                     ETVAETRLASNILDISSSSGNAAKWSGSAFIDAQQKLGDAKETLTAVAVHSAVEAELR
                     KQNLIETVQPSNSGPIYFYQNKRVIIDDGCPYEGSGSNIVFTSYLFGEGAIALGNGNP
                     VGFVATEIDRDKKKGSGVDYIINRKTFIMHPRGVKFTNENMAKTEGPSRAELSDATNW
                     KPVYEPKQIRMVAFRHKI"
     gene            complement(59334..59924)
                     /locus_tag="PC503_000063"
     CDS             complement(59334..59924)
                     /locus_tag="PC503_000063"
                     /inference="COORDINATES: protein motif:HMM:NF018515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDF2526090.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKDKHNNDLEKLKKDMEISKKEYELKGKLKDLG
                     VVDADYIIYKQGGTEKFNFDNEGKVIGLEDTIKVYKENSPHLFTGGKPNYIPKGGDDY
                     KGSNPWLEKSFNLTEQSKIYNDNPALAKELMTAAGK"
     gene            complement(59988..60284)
                     /locus_tag="PC503_000064"
     CDS             complement(59988..60284)
                     /locus_tag="PC503_000064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526091.1"
                     /translation="MFKKDTRGYIKRHIGKPNKSSVRDIISVLIIIVGIALGFIVGLS
                     IIIANVLDVANMIDTNTFTCMKLVFNLAGMIAGYLVGRIICFVLSLTGIFIGSK"
     gene            complement(60531..60791)
                     /locus_tag="PC503_000065"
                     /pseudo
     CDS             complement(60531..60791)
                     /locus_tag="PC503_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(60793..61038)
                     /locus_tag="PC503_000066"
     CDS             complement(60793..61038)
                     /locus_tag="PC503_000066"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526092.1"
                     /translation="MIKLYILSIIVFCTGLYLFKMKIDSNEELIKILKNKKVRRKCNF
                     IFMALFPLLNFILGVIFIISSLLVSNEDIIKNLKGDK"
     gene            complement(61109..61267)
                     /locus_tag="PC503_000067"
     CDS             complement(61109..61267)
                     /locus_tag="PC503_000067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526093.1"
                     /translation="MKKDNEKLFSAPRWTEIPQAKVVGERTLTEEEVKEAQEIRKKII
                     KRKINNKG"
     gene            complement(61269..62756)
                     /locus_tag="PC503_000068"
     CDS             complement(61269..62756)
                     /locus_tag="PC503_000068"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2526094.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKYYLELEKQYKLAMSSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWATDGLNFSERIWGKHRPALINELYTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCRCRTTTAPFFSDEEGYRAARGEDGKTYYVPSSMKYK
                     EWYEKYINKNIKLSDNEQLAINKYVSSDSYKINEKLRRGLSLTSEDKNFISNLDSALD
                     KMPNYKGNVNRSLYFFNEKEKIDFLNKHQIGKEIVYNEYISTSSRGEYNPSGQVELNI
                     ISTNGKDIRKYNPQEAEILFKRNSKFITTDNFEYDGKHYITMKEV"
     gene            complement(62746..64131)
                     /locus_tag="PC503_000069"
     CDS             complement(62746..64131)
                     /locus_tag="PC503_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2526095.1"
                     /translation="MNIEVVKKLIKKHVPYHSDVISKSIISERYYKNKNDILFKTSNR
                     EEEETENPLRNADNRISSSFYSLLVNQKASYLFTYPPTFDVSNNRTNKAITEVLGDIY
                     PKICKDLCINASNSGVSWLHLWKDKNSKLNYGVVDSKQVIPLWSSDLNKKLIGVLRVY
                     DEIDENGDNYIIYEYWTDTECQAYRKLDDLDIDELEVYNMFSITYGNGDILDNSNTLK
                     HDFGELPFIPFFNNNIKTSDLDTVKSLIDTYDKVFSGFVNDLEDIQEIIFILTNYGGT
                     DLKSFLEDMKKYKTVEVESNGMDDKSGLSTLTIDIPVEAREKLLMMTRKAIFEQGQGV
                     DPQPIDFGNASGVALKYLYSLLELKAGLMETEFKLSFGKLIRMICKVLNLECNIVNQT
                     WTRNAIANDLELAEICAKSVGIVSDKTVCKNSPIVEDVEYEIAQIKKEKEEAQREYDD
                     LIPNDGVIDET"
     gene            complement(64147..65412)
                     /locus_tag="PC503_000070"
     CDS             complement(64147..65412)
                     /locus_tag="PC503_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012047809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDF2526096.1"
                     /translation="MNEIRLKNIIAPSFYNVHKLIKQDVYTHYWFKGGRGSTKSSFIS
                     LEIVLGMMRDAQQGKLTNAVVIRRVKDTLRGSVYEQIQWAIYTLGVQNEWEIPESKLQ
                     MTYKPTGQVILFKGADKPKKLKSTKVSKGYIKYVWYEEVDEFEGMDKIRNVNQSLLRG
                     GNTYNVFYSFNPPESQRNWTNMEVIEKREDKFIHHSNYLSVPKEWLGEQFIVEAEHLK
                     KVNPTKYEHDYMGVVTGTGGEVFTNVTVREISNEEINRFDRVRRGLDFGYAKDPLSYI
                     VMNYDKTRKRLYIFFELYKVALGNSKAVELILKENTSNKKVIADSAEPRSINEFKKLG
                     LKIIGARKGPDSVEHGIKFLSEEVEEIIIDPIRCPNAKREFLGYELEKDKEGNFKDEY
                     PDKNNHTIDAVRYGMEDVMLKRKGLSILK"
     gene            complement(65405..65827)
                     /locus_tag="PC503_000071"
     CDS             complement(65405..65827)
                     /locus_tag="PC503_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013725420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDF2526097.1"
                     /translation="MAKLTEKQKRFCDYYIETGNATEAAIRAGYSEKTAKVIGAENLT
                     KPYLKSYIDERIGQLESNRIADAKEVMEYLTKIVRNEAKEEVVVVSEYGPEIIKKDVS
                     IRDRNKAAELLGKRYRLFTDKVEVEGTGIVQIVDDIDE"
     gene            complement(66016..66423)
                     /locus_tag="PC503_000072"
     CDS             complement(66016..66423)
                     /locus_tag="PC503_000072"
                     /inference="COORDINATES: protein motif:HMM:TIGR01636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526098.1"
                     /translation="MTDYEKLEELLNSYSNLDIEIREIELKVRGSSLRGIELNGMPKG
                     NNVSSPIENELIYVERLENEKIYLQIKKESINNMLNLLDDFEKNLIELRYFKKLQYKQ
                     ISYELNISELYVGKKRKKALDKILPFAKKYNLI"
     gene            complement(66790..68673)
                     /locus_tag="PC503_000073"
     CDS             complement(66790..68673)
                     /locus_tag="PC503_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006317348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HDF2526099.1"
                     /translation="MSFDIFKGYIITNNKKAAEKFKNVKKLKTYEQIKNLPEFAGVLA
                     EETVLVDIDDFESSEILYKIVQDLKLKCRVYKTTRGKHFLFKNTSLEKNRTKCRLAIG
                     LNSDIKLGCKNSYSILKFNNIEREILYDSKEIQEIPMYLTPIKNGIDFLSLGEGDGRN
                     QALYNYILTLQSNDFTVEEIRETIRVINKYVLKTPLQDNELEVILRDESFQKKIFFNS
                     KGSFLFDEFAKYIKNNNHVIKINDQLHLYKDGIYVDGQARIEAEMINNISNLNKAKRS
                     EVLSYLNLLISENTSMSEANLIAFKNGIYNIVDDSFIEFSPEFIITNKVNWNYNPGAY
                     SKLVDKTMNKLSCGDFEIRMLLEEVVGYCFYRRNELRKAFILTGDKANGKSTYLDMIK
                     TLLGDENTSALDLKELSDRFKTAELFGKLANIGDDIGDEFIANPAIFKKLVSGDRVNV
                     ERKGQNPFDFNNYSKFLFSANNIPRIKDKTGAVLDRLIIIPFNASFSVNDKDFDPYIK
                     YKLREQEAIEYLINLGLEGLKRVLKNRKFTVPDKVKKEILEYEEVNNPILGFFKEVDK
                     IENESTKEIYRKYQEYCILNGLQPISNIEFSRQVVKKFGYEVKDKRIQGKKYKVFTRA
                     VPG"
     gene            complement(68685..70418)
                     /locus_tag="PC503_000074"
     CDS             complement(68685..70418)
                     /locus_tag="PC503_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526100.1"
                     /translation="MIFYDFEVFSYDWLVVFIDVLNKKEEVIVNDIDKLNSFYIEHRE
                     DIFIGYNSRHYDQYIFKGLLCGFNAKEINDYIIVKGQPGWKFSNLLRNIQINNYDVMT
                     SFHGLKQLEGFQGHSIKESNVSFNIDRPLTNDEIEETIKYCRYDVEQTIDVFIERKSE
                     FEAHMGLIKAFKLPVSYIGKTQTQLTAIILEATKKEHDDEFDLQIPDTLKIEKYKEVL
                     SWYKNPLNHDYSKNLKINISNVPHVFAWGGVHGAITKYYGEGYFLHVDVNSFYPSLMI
                     RYNYHSRNIKNPQKYVEIYDKNLQLKKEKSPLRPAYKLAVNKTYGGMKDKNNNLYDPR
                     QANNVCVSGQLLLLDLIEKLEGYCKLIQSNTDGLIVKLNTIDDYELIDDICYEWEQRT
                     GMGLGFDVYTKIFQKDVNNYLVITEDGEVEAKGLYIKDLGNLDYDLPIINKALKNYMV
                     NNTPIEETINKCNDLIEFQKIVKISSKYSHGLYSPTIEGKTKKVFIGGKILNDKCFRV
                     FASKNKNDGGIYKVKNKEKNPEKFANTPDKCFIENGSVIGKKVPRKLDKTWYIDLANE
                     RLKQFGVLLSN"
     gene            complement(70632..71075)
                     /locus_tag="PC503_000075"
     CDS             complement(70632..71075)
                     /locus_tag="PC503_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003355843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HDF2526101.1"
                     /translation="MDFSKFDKAIDVKGLKEDIKEASENSGKFKDVPHGTYEVEINKM
                     ELSESKKGDPMFVCWFKILEGEYKDSLIFMNQVVKQGFQIHIVNEFLRSLETDIEVEF
                     ESYSQYAQLIMDIAEEIDGELEFAIEYGEKKGFNTFTIKDIFEVA"
     gene            complement(71139..72824)
                     /locus_tag="PC503_000076"
     CDS             complement(71139..72824)
                     /locus_tag="PC503_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003400311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2526102.1"
                     /translation="MQFSHSRIGVFKNCPYKYKLQYIDKVKTILNADSNNALILGTSL
                     HTGIEKDIDAAVKEYYFSYPSITDLHINEVMKLDYLIPKVKEILPKGFNEVQITTSDF
                     IGFIDLLAPHVYMTDTNLNTNETTIYYEDEERVFDIYDFKYSNNIDRYLESEQLHLYK
                     YFYEKQHPNHEIKDLYYVFVPKVQIRQKKTENLHQFRQRLLNELDKSEIKIVKVEYEP
                     NKVINFLVDIKRCLENKEFEKNQNKLCNWCDYQEYCEKGIDYMLLPNSERRSVEGINK
                     KTLWIYGAPFSGKTTLANDFEKPLMLNTDGNIKFVDAPYISIKDIVTVEGRMTKRQLA
                     WDVFKEAIRELEKKENDFETIIVDLLEDTYEACRLYMYDKMGITHESDDSFRAWDKVR
                     TEFLSTIKRLMNLDYKNIILISHEDTSKDITKKGGDKITAIKPNLQEKAANKIAGMVD
                     IVARVVADGDVRTLSFKTNEVIFGGGRLKVKSNEIPLDYNELMKVYEDISIEKNEIKK
                     SSKPKKSKTNEEVEMTPIVEETSEKTEKEQTEEEVIEQEEAIKPVKKTRKKRN"
     gene            complement(72825..73127)
                     /locus_tag="PC503_000077"
     CDS             complement(72825..73127)
                     /locus_tag="PC503_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HDF2526103.1"
                     /translation="MSAEKQFENKVKKFLKEQGCWFIKYWGGSAYTKSGIPDLLVCCS
                     GKFIGIEVKGEKGKASELQKYNIKEIEKAGGIGIILYPKDFDRFKKMILEIKKEGE"
     gene            complement(73136..73570)
                     /locus_tag="PC503_000078"
     CDS             complement(73136..73570)
                     /locus_tag="PC503_000078"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526104.1"
                     /translation="MIKCNEICDFKGENICCSECGDNETCSNICGLECSTCGKTIIAD
                     DAGLEEFRDNNYVLFKNIFNICEQKKSLEIEEKKMKEELKKSMELYNIKSFDNDILKM
                     IYIEASTTTTIDSKKLKEKYPEIYSDCSKISNKKAYIKISLK"
     gene            complement(73572..74750)
                     /locus_tag="PC503_000079"
     CDS             complement(73572..74750)
                     /locus_tag="PC503_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011838240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2526105.1"
                     /translation="MGLGKTFVGSEKLINLGSNTNLLICQKSKINDWVYHFKTYYPDM
                     GIINGTKKLSEGIEYFKIVEVPFIVVINYELAFRRKELLDLKDFTLMLDESSMIQNEK
                     AKRSKFVLSLNPKNVILLSGTPCSGKYEQLYSQIKLLGWNISKDLYWKQYIDVEYKDI
                     GGFPMKVVTGYKNVDRLKKKLRDYGAVFMMSDEVFDLPKQIDNVMKISTTREYRKFKK
                     DSIISISDDVELVGDTTLTKMLYERQLCSQYNKFKLEAFGDLINSTGDRLIVFYNFNE
                     ELDRLIELSRDRPISIVNGSTKDLNNYEEHNNSITFVQYQAGAMGLNLQKCNKIVYFS
                     LTLSCELFMQSKKRIHRIGQENTCFYYYMICRNSVEENIYKSLQSGVDYTNNLFEKGN
                     "
     gene            complement(74841..75014)
                     /locus_tag="PC503_000080"
     CDS             complement(74841..75014)
                     /locus_tag="PC503_000080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526106.1"
                     /translation="MLEVNIKIKGEASEIIDSIRAIFNSFGEESMTEIKAEQEYKSRR
                     SRKLKTEDLSDQE"
     gene            complement(75164..75382)
                     /locus_tag="PC503_000081"
     CDS             complement(75164..75382)
                     /locus_tag="PC503_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526107.1"
                     /translation="MKVNFNLEKLKIGNVVSVSSKRFGFNINCIVVVATEEELNLAYY
                     SKDKGCIEYQALIPEDIRYGDYILQRLG"
     gene            complement(75366..75554)
                     /locus_tag="PC503_000082"
     CDS             complement(75366..75554)
                     /locus_tag="PC503_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526108.1"
                     /translation="MGKKSEYTVTTVGEPNLDALGETLAKILTEKFGVLITHTYIENY
                     YVDKERGGDVDGAIESEF"
     gene            complement(75606..75860)
                     /locus_tag="PC503_000083"
     CDS             complement(75606..75860)
                     /locus_tag="PC503_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526109.1"
                     /translation="MNDRERIFYKIVDTLDTIADIKIADQNKIEKEVGMCIGEDNYIT
                     YCIDENLIKFYIKDEEELVIDKDSPLLYMLDTLFYEVHEE"
     gene            complement(76262..77152)
                     /locus_tag="PC503_000084"
     CDS             complement(76262..77152)
                     /locus_tag="PC503_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HDF2526110.1"
                     /translation="MNEVVNAENINEIEVIGITEVDGMKFHDIEGGFGECKKAMLVKE
                     IAEIHNKELKHINELINKNRKRFQNDIDIIDLLGVGLNDTKIKKFGFTQQAINSYRGS
                     KNKGLLTGIYLLSERGYAKLLKILEDDKAWEQYEKIVDGYFNMRKSLKENNKFNSSKP
                     KDIKDESEIKYMNAQARLKNARAREAKIYLELADKVDIKEYKQIMYSKTTELLSGETL
                     IPLPKMEKKTYSATEIGKILGISANKVGGLANAYNLKTDEFGIKVWDKAKHSNKQVPN
                     FRYYENVMPILEKALSSFEN"
     gene            complement(77215..77424)
                     /locus_tag="PC503_000085"
     CDS             complement(77215..77424)
                     /locus_tag="PC503_000085"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526111.1"
                     /translation="MKSKRNPYLKFKIFLMERGIKQSELCKILGKSASAINQNINGTG
                     GDFSVEDLRIISQTYNISIDEFFIN"
     gene            77587..78123
                     /locus_tag="PC503_000086"
     CDS             77587..78123
                     /locus_tag="PC503_000086"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2526112.1"
                     /translation="MKNTGHIIKILRIEKKLTQDELAKNLNSSFNLKLNKGMISKWES
                     NKAEPRFEYIKYISKYFDVSIDYLLGMTEYRNMYDNFDKKYDSKKLSLEVKEIEKNGE
                     KIKEKNKVLENKLLSSFSELNDIGQNEAIKRVDELTQIGKYVNKNHIDTIAAHNEHLH
                     EEGEIEKIYQDLDDMDNW"
     gene            78141..78614
                     /locus_tag="PC503_000087"
     CDS             78141..78614
                     /locus_tag="PC503_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2526113.1"
                     /translation="MNSYEKLLSEADDNNIIVREVSLISNSHGLYKNNRIALNKNTLN
                     NMSEKACVLAEELGHHYTSYGNILDLNKVENSKQEYKARLMAYNKLIGLKGIIDSFNA
                     GCKTITEMAEYLDVTEKFLNEALECYKSKYGFSATLDNYVIFFEPRFSIMNANFL"
     gene            78679..80037
                     /locus_tag="PC503_000088"
     CDS             78679..80037
                     /locus_tag="PC503_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2526114.1"
                     /translation="MLRVALYIRVSTEEQALNGDSIRTQIEALEQYSKENDFNIVGKY
                     IDEGCSATNLKRPNLQRLLRDVEKDKVDLVLMTKIDRLSRGVKNYYKIMETFEKHKCD
                     WKTILENYDSSTAAGRLHINIMLSVAENEAAQTSERIKFVFQDKLRRKEVISGTIPIG
                     YKIENKHLVIDKEKKYIVKAIFDEYEKSGSVRTLIETINNLHGELYSYNKIKNILRNE
                     LYIGIYNKRGFYVEDYCEPIISKKQFKQIQRILEKNKKTTPNKNIHYHIFSGLLKCKE
                     CGYTLKGNSSNVGEKLYLSYRCSTFYLNKNCVHNVTHNEKHIENYLLTNLKPQLHKHM
                     VKLEAQNEKIRQNKKSNKKDEKKKIMKKLDKIKDLYLEDLIDKETYRKDYEKLQSQLD
                     NITEEQESQIIDTSHIKKFLDIDINEMYSDLSRVERRRFWLSIIDYIEIDNNKNITIN
                     FI"
     gene            complement(80060..80176)
                     /locus_tag="PC503_000089"
                     /pseudo
     CDS             complement(80060..80176)
                     /locus_tag="PC503_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     ATP-binding protein"
     gene            complement(80272..81321)
                     /locus_tag="PC503_000090"
     CDS             complement(80272..81321)
                     /locus_tag="PC503_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2526115.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(81598..82266)
                     /locus_tag="PC503_000091"
     CDS             complement(81598..82266)
                     /locus_tag="PC503_000091"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF2526116.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(82272..83645)
                     /locus_tag="PC503_000092"
     CDS             complement(82272..83645)
                     /locus_tag="PC503_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF2526117.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(83642..85420)
                     /locus_tag="PC503_000093"
     CDS             complement(83642..85420)
                     /locus_tag="PC503_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF2526118.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(85537..85860)
                     /locus_tag="PC503_000094"
     CDS             complement(85537..85860)
                     /locus_tag="PC503_000094"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF2526119.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(85847..86824)
                     /locus_tag="PC503_000095"
     CDS             complement(85847..86824)
                     /locus_tag="PC503_000095"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF2526120.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(86839..87402)
                     /locus_tag="PC503_000096"
     CDS             complement(86839..87402)
                     /locus_tag="PC503_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF2526121.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(87454..87945)
                     /locus_tag="PC503_000097"
     CDS             complement(87454..87945)
                     /locus_tag="PC503_000097"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF2526122.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(87948..89873)
                     /locus_tag="PC503_000098"
     CDS             complement(87948..89873)
                     /locus_tag="PC503_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF2526123.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFNCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(89875..90186)
                     /locus_tag="PC503_000099"
     CDS             complement(89875..90186)
                     /locus_tag="PC503_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526124.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(90816..91091)
                     /locus_tag="PC503_000100"
     CDS             complement(90816..91091)
                     /locus_tag="PC503_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF2526125.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(91206..92615)
                     /locus_tag="PC503_000101"
     CDS             complement(91206..92615)
                     /locus_tag="PC503_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF2526126.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(92986..93648)
                     /locus_tag="PC503_000102"
     CDS             complement(92986..93648)
                     /locus_tag="PC503_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDF2526127.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(93902..96121)
                     /locus_tag="PC503_000103"
     CDS             complement(93902..96121)
                     /locus_tag="PC503_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2526128.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(96397..99051)
                     /gene="adhE"
                     /locus_tag="PC503_000104"
                     /gene_synonym="adhC"
     CDS             complement(96397..99051)
                     /gene="adhE"
                     /locus_tag="PC503_000104"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2526129.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            99555..99755
                     /locus_tag="PC503_000105"
     CDS             99555..99755
                     /locus_tag="PC503_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526130.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(99962..100552)
                     /locus_tag="PC503_000106"
     CDS             complement(99962..100552)
                     /locus_tag="PC503_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF2526131.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(100555..101430)
                     /gene="dpsA"
                     /locus_tag="PC503_000107"
     CDS             complement(100555..101430)
                     /gene="dpsA"
                     /locus_tag="PC503_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF2526132.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(101506..102897)
                     /locus_tag="PC503_000108"
     CDS             complement(101506..102897)
                     /locus_tag="PC503_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF2526133.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(102901..104037)
                     /locus_tag="PC503_000109"
     CDS             complement(102901..104037)
                     /locus_tag="PC503_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF2526134.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(104069..104614)
                     /locus_tag="PC503_000110"
     CDS             complement(104069..104614)
                     /locus_tag="PC503_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF2526135.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            104938..105708
                     /locus_tag="PC503_000111"
     CDS             104938..105708
                     /locus_tag="PC503_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526136.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTFYCCGNCDSEISLSQREHFKI"
     gene            complement(106162..106590)
                     /locus_tag="PC503_000112"
     CDS             complement(106162..106590)
                     /locus_tag="PC503_000112"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF2526137.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKNFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(106786..107019)
                     /locus_tag="PC503_000113"
     CDS             complement(106786..107019)
                     /locus_tag="PC503_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDF2526138.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSIFISTKW"
     gene            complement(107299..109215)
                     /locus_tag="PC503_000114"
     CDS             complement(107299..109215)
                     /locus_tag="PC503_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526139.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKSISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFFIVR
                     NNYLKEIRLNLVNF"
     gene            complement(109215..109961)
                     /locus_tag="PC503_000115"
     CDS             complement(109215..109961)
                     /locus_tag="PC503_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526140.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALLRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(110065..110916)
                     /locus_tag="PC503_000116"
     CDS             complement(110065..110916)
                     /locus_tag="PC503_000116"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2526141.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(111184..112188)
                     /locus_tag="PC503_000117"
     CDS             complement(111184..112188)
                     /locus_tag="PC503_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2526142.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            complement(112198..112890)
                     /locus_tag="PC503_000118"
     CDS             complement(112198..112890)
                     /locus_tag="PC503_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526143.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(113205..114164)
                     /locus_tag="PC503_000119"
     CDS             complement(113205..114164)
                     /locus_tag="PC503_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2526144.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(114197..115075)
                     /locus_tag="PC503_000120"
     CDS             complement(114197..115075)
                     /locus_tag="PC503_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526145.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(115068..115850)
                     /locus_tag="PC503_000121"
     CDS             complement(115068..115850)
                     /locus_tag="PC503_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526146.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(115851..116480)
                     /locus_tag="PC503_000122"
     CDS             complement(115851..116480)
                     /locus_tag="PC503_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526147.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            complement(116875..117501)
                     /locus_tag="PC503_000123"
     CDS             complement(116875..117501)
                     /locus_tag="PC503_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2526148.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            complement(117577..118548)
                     /gene="nrdF"
                     /locus_tag="PC503_000124"
     CDS             complement(117577..118548)
                     /gene="nrdF"
                     /locus_tag="PC503_000124"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF2526149.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            complement(118561..120660)
                     /gene="nrdE"
                     /locus_tag="PC503_000125"
     CDS             complement(118561..120660)
                     /gene="nrdE"
                     /locus_tag="PC503_000125"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF2526150.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDKWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            121138..121863
                     /locus_tag="PC503_000126"
     CDS             121138..121863
                     /locus_tag="PC503_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2526151.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSVDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            complement(121991..123187)
                     /locus_tag="PC503_000127"
     CDS             complement(121991..123187)
                     /locus_tag="PC503_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526152.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(123190..124215)
                     /locus_tag="PC503_000128"
     CDS             complement(123190..124215)
                     /locus_tag="PC503_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2526153.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            complement(124287..125417)
                     /locus_tag="PC503_000129"
     CDS             complement(124287..125417)
                     /locus_tag="PC503_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2526154.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTQEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     regulatory      complement(125645..125826)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(125879..126772)
                     /locus_tag="PC503_000130"
     CDS             complement(125879..126772)
                     /locus_tag="PC503_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF2526155.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            complement(126852..127754)
                     /locus_tag="PC503_000131"
     CDS             complement(126852..127754)
                     /locus_tag="PC503_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2526156.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(127804..128964)
                     /locus_tag="PC503_000132"
     CDS             complement(127804..128964)
                     /locus_tag="PC503_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2526157.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNLD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(129120..129425)
                     /locus_tag="PC503_000133"
     CDS             complement(129120..129425)
                     /locus_tag="PC503_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2526158.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(129523..130497)
                     /locus_tag="PC503_000134"
     CDS             complement(129523..130497)
                     /locus_tag="PC503_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2526159.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            131079..131855
                     /locus_tag="PC503_000135"
     CDS             131079..131855
                     /locus_tag="PC503_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2526160.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            132188..133333
                     /locus_tag="PC503_000136"
     CDS             132188..133333
                     /locus_tag="PC503_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2526161.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(133488..134357)
                     /locus_tag="PC503_000137"
     CDS             complement(133488..134357)
                     /locus_tag="PC503_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2526162.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(134475..135188)
                     /locus_tag="PC503_000138"
     CDS             complement(134475..135188)
                     /locus_tag="PC503_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF2526163.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKSKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            complement(135559..136947)
                     /locus_tag="PC503_000139"
     CDS             complement(135559..136947)
                     /locus_tag="PC503_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2526164.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEEL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            complement(137068..138345)
                     /locus_tag="PC503_000140"
     CDS             complement(137068..138345)
                     /locus_tag="PC503_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF2526165.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            complement(138482..138817)
                     /locus_tag="PC503_000141"
     CDS             complement(138482..138817)
                     /locus_tag="PC503_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526166.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
BASE COUNT        45251 a        24448 c        15535 g        53816 t
ORIGIN      
        1 ttaatactat aaataaaaac gaagcatgat ttttatttaa ataaatctca aacttcgtct
       61 ttacttactt agatatttat ttactttcta aatcctatta tttttaaaac cttatctttt
      121 taatacttca ccacatttat tctcagtaat ctctccattt tctagcgcaa tttttccatt
      181 tacaattaca tattcaacac cattggctag taattgtggc tttgaaaaat caatatcttc
      241 tgacctagga taactatagt tatccatgtc aataactgct atatcagcta tcaacccttc
      301 tttaagaata cctctatttt ttattttaaa ttgcctagct ggtaatgaag taactcttct
      361 tacaatctct tccaatctaa caccagactt tctgtacata ttgaagaaaa ttggaaaagc
      421 tcctcttctt tgtagttcaa accatgacat atccccaccc acactaaaca aacaatctga
      481 accaaccata acaaatggat tatcaattat tttatcatca tgtagtttat ctgggaaatc
      541 agctctatac attcctccta aacaaaagat aagttcttcg tctccatcta aaagtaaatc
      601 gagtaataac ttgtcctcat ctattccttt ttgtgtagct atttcacgta ttgatttctt
      661 ttccatatta atatctttag tgtttagaag tattatactc cccctatctc caagtataaa
      721 tgcttctttt aatataagtg ttcttccctc ttcatttcta agagcatcca ttaccccatc
      781 tatacctaat tcaaatagac tagatgatat tgccataata aattgaatta ctcttttttt
      841 cttcatacaa tgcccagaac ttcttggtac tgtgtcaacc attatttcaa caccattata
      901 cctagccttt aatatctcat caaatgcttc tatttcaact ggacttaagt gagatacttg
      961 aaccctagca ccacttttct gcccaacctc tatggcttct tttactgcat tatatcttcc
     1021 tatgtaatct ctaatatgag atgtatatat accatcatgc tctttaatct gccttgcaat
     1081 atcaacaagt tcatcaatat cagcatactt acttggtata tatgccaatc cagtagatat
     1141 tccaaaagca ccacttttca ttccatcatt tattatatct gtaatttcat ttttttcctt
     1201 ttctgtagga ggtctatcct tagaacctcc cataacactc catcttatag tcccatgccc
     1261 caacaagaat cccatattga cagaaatacc acttttagat ataaggtcac aatattctgt
     1321 aaaattattc caacatttat ttttatctat aagatacttt ttttcttctt caagtaatag
     1381 accattttta tacatatatt catatacatt ttcagaagaa tatggtgtta tagaatgtcc
     1441 acaattacca tttatagttg ttgtaactcc ttgttttaga aacttttcaa atttaccatc
     1501 tagtattgct actatttctt catgaacatg agggtcaata aatccaggtg ttataatttt
     1561 tccataacaa tcaatctctt tatttgtatt gctatttatc ttagaatcta tttttgctat
     1621 taagttgtct ttaattgcta tatctccata aaaaccagga ttacctgtac catctattat
     1681 aaatccattt tttaagatta aatcatatat caaaatattc cctccttaaa aaccaatttt
     1741 taaataatct taatgtaatt tttatatttg aaaatcaaat tattaaattt catatttgaa
     1801 aattcactat tatttcattg taattagtca ctaagcttat ctttatacat agctcttgca
     1861 attaatatag taccaaatac acatataaga actactagag actgtggtat tataccttgc
     1921 tttgataata taatagtcaa tacagatatt acaattgcta ctagacctaa ttttttatct
     1981 tgtaaaaata cttgtccaaa aactgaccca aatagagctg gtaaaattaa gtttaatttt
     2041 tctactactt cagctggaat tttagatagt acgcttcctc ctaaaattac ccctatagtt
     2101 agtatactta tattcactaa aatagataca gctattccta ttgtagatat tatcgagcct
     2161 tcttctgtac ctgattcaac ttctgctgcc ttttgagctg ctattgaaca tggtagcctc
     2221 atattagata tattaccaga aagaaaactc atataagttc ctgggatacc taagattggt
     2281 gaataagaaa ctggttctat tatgtaattt ggagcactca tactgacaat tgccattgta
     2341 cttgctaata atgctgatat tggaggcata ataccaaatc caaagctcaa aattattcca
     2401 ggaactaatg ctgctataat acccaaagat agtgttagtc ttccatacct tatcataaaa
     2461 ggtaaatatt cttcattgta tatagatttt actttactca taaaactccc cccttatatt
     2521 actgaagcta ttatcattcc gctaaacatt gatattgtaa gcccccactc tcttaaccat
     2581 tttatatttt tcttcttttc aagcatacac aatattacca ttatagccat tccacttata
     2641 catgcaattg ttccattatc aaaacgcaac accctatcag catttagata tgcaaatgaa
     2701 cccaacattg ctcctagaga tattattggt ataaatgatt tcttgccact agatataaca
     2761 ttggttatct tatctagttt atgtccaaat agtaatgtga atattatcca tcctaaagaa
     2821 cctaatatca tagtccaaac tgcatttgta aatgcaagtt ttgtcatttc aggagaacct
     2881 aaagttatac ctaatgcatc tgttccaaat ccggctgaca ttgattcaaa aattacagaa
     2941 cctataaatg ataatctcat ccatgctata ggcccaccca tagttactat aagcgatacc
     3001 attccagcaa atatagtcat tgaaggccca atagctgaaa tagcactact cttaacagct
     3061 gactttattt gtttatctgt tattcccatt gttttaccaa ctttgcaaga ttttatagca
     3121 aatataaggg attgtaccac tactattgat actgctactg tactcgctat ccacaaaagt
     3181 ggatgattag ctaattttaa ataatccatt tataaaacct ccctataaat cctcaaattt
     3241 tattaatatt tctaatatat ctatttccaa acctgtttta gtactctaag tatatttcca
     3301 cctagtacct tctctatttc ctcatcacta tatccatgct ttactaaata tctaacaatg
     3361 ttttttgaag tttctgttgg gttctcaaga ccttttacat attctacttt gggatgttct
     3421 tttgttcctg ttattttttt tatatcaaat ttagcagcta gtactgagtg taattttaca
     3481 tggtcgccat atactgtatc tggtccaaaa gctacatggt ctattcctac taaattttta
     3541 atatactcaa aatgttccat aaatgactct attgaatgtt ctttattctt ctctgttatt
     3601 gtagtatgag gtgctgcttc tacacctata acccctcctt ttttagcaca tgctattaat
     3661 acttcatctg gagttagtct ctttgtgttc cataaacttc ttgccccaac atggcttaat
     3721 attattgggt ccttgctata ttctattaca tcaagtgtag tttgaactcc aacgtgagag
     3781 caatctattg ccattccaat tttattcatt ctttcaacag ctttttttcc gaaatttgta
     3841 agacctccat ctttctcttc ttttagtcct gaacctaatg cattggattc gctgtatgtt
     3901 atacccatta accttatacc aaatccatac agtatatcta ttctatcaag ttcattttct
     3961 attggtgctg caccttctaa tgttggtatc aatgctactt taccttcact tttagctctg
     4021 tatatatctt ctactttttc acactttata acaaaatctt gatgagctaa atcacatagt
     4081 ctcatgccta aatctattaa tatatcatcc catttccacc ctgaatttga tgttatcgta
     4141 catacaccat ccattaaatt atcaaatata gcatcataat atcctcttga taatgcttca
     4201 taagcacatc tttgtttacc ttccctatta tattcaaata tatctctttc taggtgttct
     4261 ggaaataata ctggatgttc atgtaatgat ataaatattt tttcatccac tatactttta
     4321 accttagctt cttgaatatc atctaattca ataaggtatt ctttaactct tttatctcct
     4381 ttacacatct caatagatga aatatctttt cctttttcta aataactata ggcttcatat
     4441 cctttgtaag ctgacttcat aacaacatcc tccaagttct acaatttttt atatttttcc
     4501 tatgtagcaa ttgatgtgcc aaaatataaa ttttaattgt ataataaatc ttgcaaaaaa
     4561 taaaaacagt agtaaggttg atatttacta ctgttttatt aaaaataatc ttcttagatt
     4621 atttattcaa tatttttgaa ttatcttaat cttaaagata attttattta tttctatcca
     4681 ttatagggat ttttttaggg tgttttgcct ttttagtccc ctatatcact cccttaattt
     4741 ttacatatga tataaagttc tttccttcat cagttataaa actaccttgt ttttttactc
     4801 cagataaaag taaaccatgg ctctttaact tatctattct ttttctaatt tggtctacac
     4861 ttaaaactat atctttttct tttaaaatct cttgcagttt atttcttcct aataatatat
     4921 ttttattatt ccaagtttct atactggtca atatacatat actttcctca aagaaattag
     4981 attgtttgaa atctaagata attgaatcga aattttcatt aactaaagta ttgttttttt
     5041 caaatctaaa ttgttctggc aaatgctcgt aatctactct atcttcctca actatagtat
     5101 caatataata aattaaattt ttaagctctc ttacatttcc tggccattca tacaatgtta
     5161 aagcttgcat tgattcctct gtaaaacatt tgttgctatt tatttcatct aaaaaatact
     5221 tacttataag aggtatatct tccttacgtt ctctaagtct aggtatctct atatgtaata
     5281 cattaatcct ataatacaaa tcttctctaa aagaaccttc tttaattttt ttctttaaat
     5341 ctttatttgt tgcagctata attctaacat ctattggtat aattttactt ccgcccattc
     5401 tcataacttc tttttcctgt aatactctta gcaatctctg ctgtacatct aaagatatat
     5461 cacctatctc atctaaaaaa attgttcctg tatgtgctct ttcaaatata cccatttttc
     5521 caccttttat tgctcctgta aaacttcctt catcatagcc aaaaagttca ctttcaataa
     5581 gtgtatctga caaagaagat agattaactg caacaaatgg cttgtttttt cttagagatt
     5641 cattatgtat tgcctgggca aatatttctt ttcctgttcc attttctcca agtatcaaca
     5701 cagaaaagtc tgtagttgct atttttcttg caatattaat tttttctttt attattttac
     5761 tctcacctac aacactctca aatgtatact ttgatacaaa accttttgac tgaagtttat
     5821 tttgaatctt gtcctcaagc acttgaattg cacttatatt tttaatgctt ataatactct
     5881 ttattcgttc attattttca taaacattta ctttattaat tatcagtttt ttgttattta
     5941 aatttactac ttcatcatta acttcatctt cttgaaaaaa tatttttttg acaaccttat
     6001 cactaaataa gtccataaag ttattagata taatttcatt ttggtctatt ccaactagat
     6061 tagaaaatac tttgttgcaa tatataaatt ttcctaattt atcaacagaa gcaatacctt
     6121 catctataat ctccaaaaaa ctcttcatgg ttttattcat agttgtataa tacctatatc
     6181 cacttactgt atcttcattg tatttttcct taataatatg tagtttatct atagatatat
     6241 ttagttttgt aaagatttct ataactgtat ttatatcaat taccttatca cctatgtcaa
     6301 ttatttgctt tatgttttgt ggtatgctgt ttctgcttcc cgtaataatt ccaatctcac
     6361 atttagactt atcacaacct ggataatatg gtattagatt aatatgaatt aatcctagtt
     6421 ttctaattat cttggcagtt tcatctgctg actctttata agcatctata accataacat
     6481 cagaatcatt ttctatactt attatctgat ttatattttc aatatttata gtacgatgta
     6541 ctattacaat aggtatattt ttatcaatat tattatgtat atattccttt atatcattgt
     6601 ctgaacatac tacaagctca tagcttgaca gttcaatatt tatcctattt acatatacca
     6661 agttatctat attacaaaat tctccaaata tattttccaa ttgttttgat atatctatat
     6721 ttattttgtc atcagttgat acaaataaaa tattatgttt tttcatagtc ccacctcctg
     6781 tttaacgagt atagaaagta ataatttggt ctattgtagc actttttaaa aaagttttaa
     6841 atcttaaaaa tcaaattttg taccatttac tattattttc cataataaaa taatgtaagc
     6901 tatctttttt cacatataat ttaatttcta aaacggttag tttgacatta ttggaatata
     6961 aataaaaatt taatataaat tcgttaatat attaatacat ttttaagaat gacaaggaat
     7021 aaattataac aaattttagg aatatataat aatagggtct cagaacttag ttacaagttc
     7081 taaaacccta tttgtttagt gtaaaaaaca tcataaaatt tagcttaaat cttttcacat
     7141 aatattactc tttttctaag tgataataaa atatatctat tcctctaaaa actgtaaaaa
     7201 ttcctgatta aatagtttaa gctcatcata gaatatagca tgaccactat actcaaaagt
     7261 atataaaatt gaatcttcta ttttttcatt cataaaaact gcaaattcat acggacatat
     7321 ttcatctaat ttcccatgaa atataccagt aggcactctt acacatttta aatcattaaa
     7381 taattcttca tctcttaaag atacagcagt tccaatagtg ccaatacctg atgcactaaa
     7441 accaatatca ttaaaccatc ttctaaagct ttctggtgga tttgatgcaa atactttttc
     7501 gccaaaatcg gttaccattt ctggtctatc agtacatgct tgtgctatca atttatttac
     7561 atcttcacgt gtcataccat atggaaattc tggaggtctt tgtacaaatg atggtgcagc
     7621 agctgcagct aataccaatt ttgacactcc atatccatta aataaactca tatacctaag
     7681 tacgattgct cctcccattg aaaaaccaac aagggtaaag tcttttaatc caatagcatg
     7741 taccacctta taaatatcgt ctgctaattg gctataagta tatcctcctg atgttgcatc
     7801 agatttacca aaacctctta aatcaattga aactgttcta tatccgagtt ttggcaatat
     7861 atttgtttga tattcaaata tcttatgtcc taagggccaa ccatgtataa aaagtacagt
     7921 ttttttagca ctcggattca aatcatatac tgctatgttt atatcattca catatacata
     7981 atacatatca acagcaactc ccttcaagaa aatgtatgat ggttatttta tatatatgaa
     8041 taaaatgatg aataactaaa ttttcaaatt tatttacaat acttctctat tgccttttca
     8101 aataaactta catgaagttt ttcatctagg attattctat ttaatatagc ttttatataa
     8161 gggtcttcaa taagacttat atctttataa taattattaa tagccacatg ctccaaatgc
     8221 aaatctagtt ttaatctgtt acaaatagaa tttccataac atacaaaacc accattccaa
     8281 tatgcaccac aagaacttgt agaacctcta tatacaggat ttccacccaa taatcttata
     8341 gtctttgcta atatctccat atgtaacatt tctgttatag atatatttat ccacatttca
     8401 cttaactctc tatgcgtttc atctaaatca aaattatggt atagatattg atttacactc
     8461 gtaaattcac ttgatactcc agcatagtca tccatcaata attctgcata atacttattt
     8521 ggacctaaaa cttttatctc tggatatggc tcatcacttg aatatccatt tcgcttgtgc
     8581 atgtcataat gtgcaccact cataatatct cctcctttaa atttaatgta tgatattaat
     8641 tgtatgcatc acaacttttt catataactt agataataaa atctacttaa ataataaaaa
     8701 gccatattaa ttaaaattaa catgaccttt tatccacaaa attacttttt aattattcat
     8761 cttttccagc tactgatagc tctttaataa caactgaagg tgaacctata ctactcattg
     8821 gaaattctaa atcttctcct atagcttcaa tatctttcaa caggtcaaaa tagtttcctg
     8881 ctactgtaat ttgctccact ggaaatactt tttttccttc tttgatataa aagcccttgg
     8941 cagctaaaga aaagtctcct gttactgaat ttgcacctga atgaagtcct gcaaagctag
     9001 taaccatcaa tccttcatct atatccttta taatttcatc taaagattta tctcctttct
     9061 ctatataaaa attagttgga tatatgctta taggtgatga atatgaagat tttattccat
     9121 ttcctgtagt ctttacacct gccttattag ccgtttttaa gttatgaagt aaagttataa
     9181 gctttccatt taaaacaact tcttttttaa atgtagctac tccttcatca tcaaaaggag
     9241 tagatgccat accattttct aaaagtgggt catcaactat tgtaactata ggagatgcta
     9301 tcatgtctcc ttctctattt ttcaataaag ataatccttt ttgagctgaa tctgcattaa
     9361 atatcccaga aaatgtgcta agcaaagata ccatagcttc attaagcaat atagttttat
     9421 atttacctga tgtaatactc ttaccaccta ctttagataa agcattatca acaccaagtt
     9481 ttgctatctc acaaggtttt atttcttcaa tagaatttgc tatattatat cctattccat
     9541 catatttttg tccattgtct tctatgatag gaactacaaa ccctataagc atattagttt
     9601 tattgcttaa attaagacct ttagtattag atataccatt acttgataca gaataagata
     9661 tagtacattt agataaattt accaccttat ctgaataagc tttagtctct ctttccattt
     9721 ctaaagctaa atcaatcaac ttatctgcct ctaaattttc tagctcttta gaataagtct
     9781 ttacatcatt atagtgctta tctccttcat atataaattg tacatcttca ttttcaatag
     9841 tgtttactcc atcttttaca ttttttatca acatatcaac agctttatca tctaaaattt
     9901 ctgtataaga ataacctatc tttccattta ccttacctct aaaagataaa ccaaaagatt
     9961 tatcaagatt gtatttctca acttctcctt catatatatt tatacttaaa ttttctcctg
    10021 tataataata tatttcacac tcttcaaaac cttcacttag agccttttta aataatatat
    10081 ctttaaaatt tttaagttcc acaattatcc ctcctatctt ccacctacag taatttcttt
    10141 tacccttatc ataggttggc ctacattagt tggtatactt cctgatgatg agccacacat
    10201 cccctgagct tgttttacgt tattcccaac catatctata ttcataagta tatcgctacc
    10261 ttttccaatt aaactagcac ctctaactgg ctcttgtatt tctccatttt ttattaagta
    10321 accttctgaa actgcaaaat taaactctcc tgttacagga tttacagaac caccacccat
    10381 ttttttagca taaagtccat ctggtattga ctttataata tcttctggtc tatcttctcc
    10441 agcagcaata taagtgttag tcatccttga agttggtgca aatttgtagt tttgtctacg
    10501 agaacttcct gtaggattca ttcccattcg tctaccatta agtttatcta tcatataaga
    10561 cttcaaaatt ccactttcaa tcagtatatt cttttgagtt ggatttccct catcatctat
    10621 attcatagaa ccccagtagt ttggtattgt accatcatct atagctgtaa tctttgtgga
    10681 agcaatctgt tgacctaatt tatctgcaaa tacagagttc ccctttgcaa ctgatgtagc
    10741 ttccaaagaa tgtccacaag cttcatgaaa tattactcca ccaaatccat tatctattgc
    10801 taccatcata ttacctgcag gacaattttt agcatgcaac atagtatgcg ctactctagc
    10861 tgattctttt gcataatatt ctgggtctat ttcttcaaat atttcaaacc ctttacaacc
    10921 tccaggacct tcaaatccag tttgattttc attaccctta gatgcaattg aacttatccc
    10981 tagtctagtt cttattcttc tatcctcaac atatatacct tcagtgtttg caattaatat
    11041 tttttggtct ttatccaaat aactgacact tacttgagat atatcattac taaattcttt
    11101 tgcactctta tatgcaacct tcataacact tactttatct ttatttccta ttgaatttgg
    11161 ataaattttt atattatgta tgttatttat tttaatactg tcatttaata ttacactttt
    11221 tccatcttcc aatttaccta aagcaacagc agctttgtat gctacatcca acagactatt
    11281 taatgaattg tcacttgtat aagcatatat acttttcaat cctttaaata ttcttattcc
    11341 tataccataa tttcttccac ctattgcatt ttctacttta ttatctatta aactaataga
    11401 attatttata gtgtcttctt caaaaatctc agcaaaatct cctccagtaa ttagacattt
    11461 ttctaatacc ttagaagcta tattttttga aagcataaat ttacctccta ctttaaattt
    11521 ttaattaact tttattcaat ctttttactt gttaacaaac attatatact atattactta
    11581 aaataaggta attatgaata tattatacat atgttttata ctaaaatgtt atcacatttt
    11641 atctatacat acccatataa ctagataatt aaaatgtata atattatttg ctatagaaaa
    11701 taatacactc atacataata aattttagga gtgaagtata tgaatcaaga atatgtaaaa
    11761 ggaaatccta tttttactaa tattaataaa gttccaagac aatttccata ccttactgat
    11821 gatattgata ctgatgttat aattgttggt ggtggcgtaa ctggatgtat ttgtgcttac
    11881 tatctagcta aaaacaatat aaagtctgtc attcttgaaa aaggaaggat tgcacatgga
    11941 agcactagcg tgacaacttc tctattacag tatgaattag atgacaattt gatagattta
    12001 acagaggtta tgactctaaa agatgctcta aaagcataca acctttgtac ttcagcactt
    12061 gaagaattag atacatttat agagctatat ggaaataagt gtgattatgc caaaagagat
    12121 actctacttt atactgccaa caaacttgaa gttaaggcta tcaaagaaga atataactta
    12181 agaaaagaaa atggatttga tgttgaatat attgatgaat ccacaaaccc ttttagcttt
    12241 gatttaaaat caggattgat agcaaagaat ggaggacgag aattagaccc atataaatat
    12301 agtcaccatt tgattgatgt aagtttaaaa aatggtcttc aagtatatga aaatacagaa
    12361 gtaaaaaaag tagatttatc aaatgataag gttactgctg aagtatcgta tggatacaaa
    12421 gttcatggta aaaaattaat tgtagctaca gggtacaata caagtttatt tacaaaaaga
    12481 aattttgcaa ctaagtcaaa tacttttaat atagcaacga aaccacttaa aaacatagct
    12541 tcttggaaaa acaacatttt aattagagat aactgtgacc catataatta tctaagaact
    12601 actaaagaca atcgattaat tataggtggt gaagatgtaa gttttgatga tatagaaaat
    12661 gaaactttag ccaatgaaaa gtatgatatt ttagaacaaa gattgaaaag tatgtttaag
    12721 gatataaaag acattgaagt tgaatataaa tattgtggtt gttttgcttc aactttagat
    12781 aatttaggtt ttattggtcc agataataaa aataacaatc tatggtattg cttaggttat
    12841 ggagcaaatg gtatactctt tgcaatatta ggaggtataa tgttaagtga attatatctt
    12901 ggcaaacaaa ataaaaatat gaaattattt aaagtagata gatttgataa atagatatta
    12961 tatattaaaa gactgtaaaa agatgaaact ttataattct aaaagttaac tttgatacag
    13021 tcttttataa tgttcctttt aaaaatactt tatttataat taaatataaa gtaaaatgtt
    13081 aaaatataac taataaaatt tagtcataag ataatattta agtttatttg atgaaatatg
    13141 gaggaattat tatgaaggaa atactcgtta ttgctcccac taaaggaacc tatgaaaaat
    13201 caattcacat agttaaaaaa aacaaatata caaatattga tgttgtattt ggcaatctaa
    13261 aagaaggtat acctcttgct gaaaaaagta ttaatcatgg tactagaatt atcataagcc
    13321 gaggtggaac ttacaatatg ttaaaagcta cttacaatat acctatagtt gaaattaaag
    13381 tagatgctta tgatattata aaaagctaca aggaggtaaa aaattccaac gaaccatttg
    13441 gaataattgg atttaataat gtcatctacg gtttcgatat tatagaagaa atattgaata
    13501 agaaaataac tatgattgaa attgaaaaag aagaagaaat ttatgatgct atagaaaagt
    13561 acagaaagaa aggtataaac acatatatag gagataccac tgttgcacat attgttaaga
    13621 gacttaattg taagggaata ttaatcgaat ctagagaaga aaacatactt agagccattc
    13681 aacaagcaga acaaatactc gaagcaacca aggatgaaca aaaaagaaga ttacagatag
    13741 aagctatgac agattttgta catgatggaa taataacagt tgataaaaat tttaaaataa
    13801 cattatttaa taagagtgct gaaaaaatat ttggtataaa aaaagaaaat gcactttatc
    13861 ataatgttgt agatgttatc ccaaacacag ttcttccaca agtagttgag actatggaac
    13921 ctcaaattgg tgaaatacaa aatataggga gtacaaaaat tattacaaat agagttccaa
    13981 taattgttga tggtcagatt caaggggctg tttcaacatt tcaagatagc aaggagataa
    14041 gttcttttga acatacaata agaaggagct tattaagcaa aggtctatct gctaaataca
    14101 cttttgatga tataattcat gctagtgaaa agacaaaaga ttgtatagaa cttgcaaaaa
    14161 aatatgcttg ttatgatact cctatgatta ttactggaga atctggagtt ggtaaagaac
    14221 tattttgtca aagtatacat aactatagta agcgtaaaaa tgcacctttt gttgctgtaa
    14281 attgtgctgc catacctcca tctctaatag agagtgagtt ttttggttat gaggaaggtt
    14341 catttacagg tgctagaaaa aaaggtaaag caggtgtatt cgaactagca catgaaggca
    14401 caatcttcct agatgaaata agtgaaatcc ctcttgaact tcaaggtcga ttattgaggg
    14461 tattgcagga aaaacaagtt atgagaattg gtggtgataa agttattcct atagatgtaa
    14521 aaattatctg tgcttcaaat aaagacttaa aaaatatgat gcgcaatggt ttatttagac
    14581 aagaccttta ttttagaata aatatactaa cattatatct tccttcatta aaagaaagaa
    14641 aagaagatat tataaaatta tcagaatttt ttatacataa atattcaagc aaatacaata
    14701 aaacgccttt aattatcact ccaaatatta aaaaggcact tcttgaacga gaatatgaag
    14761 gtaatataag ggaattggaa ggtatgatgg aaagggctgt tattgtggaa tcatttgact
    14821 cgattttatt agaaaagctt agcaatgaat atacaaataa tatagttgat aaagataata
    14881 gtgattttga atgcagtaat ttagatttaa aaactttaga aaaaaaatat atctataaaa
    14941 tttataacga aaataataga aatactacaa aaacctgtga aattctaaag ataactcgct
    15001 ccactctatg gcgtaagtta aaagaaatag aagatgatgt ttaaaaataa tacatatcta
    15061 tatatatcaa aacgttttat gtttaatttt aatacataag acgtttattt gttttcaata
    15121 aaaaatacaa ttatatgcta aaaagaatct ttgtaagtga aattctcgtc aatcatactt
    15181 ttaattataa gtaatctaca gcatttcaat cgattattaa aaataatcat gataactaaa
    15241 gatacaaact ctatatattg gcatagtaat tgcttttata atacctatat aaaaatgaaa
    15301 gggagtgata ctagatgcac atcttaaaat cagtgaaaaa gataccagga ggacttatgg
    15361 tctgtccctt gttattggga gcactattta atacagtatg tccacaagct cttgaaattg
    15421 gaggattcac aacatcctta tttaaaactg gtgcaatgag tatacttgct ctattttgtc
    15481 tatgcaatgg agctcaaatc aatatcagac aagctggtaa accattgact aaaggtatag
    15541 tacttacagc aacaaaattt ataattggtg cagtattagg tattattgtt agtaaattta
    15601 ttggacctaa aggtataatt ggtattacac ctcttgccat agttgctacc atgactaatt
    15661 caaatggagg tctatttgct gctcttgcag gtgaatatgg agactccaca gatgttggag
    15721 caatatctat cttatctcta aatgatggtc ctttttttac aatgcttgct tttggagtaa
    15781 ctggacttgc aaatgtacct atagtagcac tatttgcagc acttatacca atactacttg
    15841 gatttatact tggtaacctt gatgaagata tacgagaatt tcttgcacct ggtacaacat
    15901 tattaattcc tttcttcgct tttcctttag gagcagcatt aaactttaat caaattataa
    15961 ctgctggact acctggagtt gtacttggtt taggagttac tataataaca ggtatgggtg
    16021 ggtactttgt aatgaaactt atacgtgcag aacatccagc agtaggtgca gctacaggta
    16081 caacagccgg aaatgcagct ggtactcctg aagctttagc agctatagac cctactctag
    16141 ctacaatagc agctgtttca acagtacaag ttgctgctgc tattattgtt acagcaatat
    16201 gttgtccaat gttagtttcc tatctagata aaagagaaaa aaagaaaaaa tctattttta
    16261 aaacaaataa aaatattgaa gtaaattaat acttaaggag gtaaaattaa tgaatgcaat
    16321 tattcatgca aatgaaaaag ataatctagt tacatgtgtc agacctttaa ttaaaggtga
    16381 aaaagtttca attgatggaa agtcttacat agtaaatgat aatatacctg tctttcataa
    16441 gatggctaca gaagatgtaa aaaaaggtga tgttgtatac aaatacggtg aaattatagg
    16501 aattgcaaca gttgacataa aaactggtga ctatgttcat gtacataaca ttgaaagtac
    16561 acgtggtcgt ggagataaaa aataggagga agttaaaatg aaattaatgg gttatttaag
    16621 agaaaatggt cagtttggta ttcgtaatca tgttttaatt attccaacat ctgtatgttc
    16681 aagtgagaca gctacaagaa tagcatcact tgtgcctgga gcaatagcaa tccctcatca
    16741 acatggatgt tgtcaaattg gttctgatat agagcttaca gcaaagacat taataggatt
    16801 tggaaaaaat cctaatgttg ccgcagtttt agtagttggt cttggatgtg atggtattca
    16861 agcaaaagaa ttagcatctg aaatagctac aacaggaaaa aaggtaaatt acgttgttat
    16921 acaagaatgt ggtggaacat taaaaacagt ttctaaggga gctgaaatag taagtaaaat
    16981 ggctcgtgaa gtatcaaaag aagtaagagt tgaatttggt atgagtgaaa ttacattagc
    17041 acttgaatgt ggtggttctg acccaacaag tggaatagct tcaaaccctt caataggcgt
    17101 tgcatcaaac cttcttgtag atgaaggtgg aagtagcata ctaagtgaaa ctacagaagt
    17161 aattggtgca gaacatttgt tggctacccg ttttgaagat gaagaaatga aagataagtt
    17221 tcttaaattt gtaagtgatg tagaaaaaag agcaattgct atgggagaag atttacgtag
    17281 tggtcaacct actccaggca ataaagctgg tggactttca acaattgaag aaaagtcact
    17341 tgggtgtatg tataaggcag gcaataagcc attcaaaggt gctcttgaat atgctgatat
    17401 tgtacctcct gataaaaaag gattatattt tatggatact ccaggtcaag atatagattc
    17461 tatcactggt atggtagcag gtggtgcaca aattgtaatc ttttcaactg gtagaggtac
    17521 tccaacagga agccctattt caccagttat taaaatcact gggaatagtg atacatacaa
    17581 caaaatgcca gacaatatcg atataaatgc aggtagaatt ataacagatg gtgctaaaat
    17641 agcagatata ggtcaagaaa tatttaatga aataatagaa gtctgtaatg gtaaacatac
    17701 caaagctgaa agtcttggtc atagagaatt tggcatttac agaatttcat ctacatttta
    17761 gattgtaaca aaatatcttt tataaatata atacttatgt agatacataa gctaaaagtt
    17821 ctttctaata ctataaaaat tttctatact gaaaaggaac tgtatcaaaa ttattttgaa
    17881 aacagttcct tttttaacct cttttactca aaatattata aaataagatt taaacaataa
    17941 acgtatcttg attaatctct aagaagacat aaataaagct aaatgtaaag tgggataaat
    18001 aaaatttaat atctttgtat gaaaagatat ttggtataat atgtctgaga gaattcttat
    18061 ttgtaaacaa ataaaggatg gaggatgaaa caaaagaatg aactttgaaa acacaaaaaa
    18121 taaaaaaata atagctactt tactattgac actcctttta atcgtgtcat taacatgtgt
    18181 cacttttatt atgaatctaa ataaagtaac acataatgaa acagaacgat atcttgtaga
    18241 agtttcacaa agtatttcca ctacaattaa tgtgaaatgt aaaagtatat ttaggacact
    18301 atattctatg ggagatactt attttgagat taatgatagt gaaaaagaag tcaatagata
    18361 cttatcaaaa aaattaaaat tatttgaatt tgattggtta ggtattatag attctaatgg
    18421 aaattttgta agtgccctta aagatacagg taatgttaaa ggacaagact tttatagaaa
    18481 agcccttcaa ggcaaagaaa caattactcc tgttaaatca caatctggta catatggaat
    18541 tttatattct gtaccactat acaatggtga taaaattgtt ggagctgttg ctgcttggaa
    18601 tactattgat actatgagaa atttattaag tgtagaaagc tttcatggtg aaggattttc
    18661 ccaaattatc gaccaagatg gaaattttat tgtaagttca gcaaacaaaa atgctccaaa
    18721 aaatgtggta aatttttttg acatgattaa acaccaagga aaacaggttg ataaaaataa
    18781 acttgaagaa atgaaaataa acttaaaaaa gaacaaaact ggttctatgt attatacatt
    18841 aaatgatggt atttctaagg caatgcatta tcttccatta caagaagaaa acttatacct
    18901 cctttcaatt gttccaacaa aaacagcaag tgcacagttt gatttacttc taaaaaaagc
    18961 aatcttcatc aatattttaa ttgttatact atttttattg cttattatat tgattatgtt
    19021 tataaatcaa aagaacaggg cacaacttat aaaaatcgcc tatgtagact ctgtaactaa
    19081 aggttacagt aaagcacgtt ttgatattga agctaaaaaa attatacagt catcttcatc
    19141 agaaagctat tcattggtat ctataaatat tcagaaattc aaacttatta atgattcttt
    19201 tggtagtgaa gcaggagata aaacattaaa gtacatacat gatgtcatta gtaattatct
    19261 agaaccagga gaattgcttt gtcgagtttc taatgaccag tttaatgtac ttattaaaac
    19321 tattcctcaa aaagaaattc ttaagtacat agaaaatatc accaatgata ttaatagttt
    19381 caataaaaat gaagaatgta aatattttat agctctatct ataggtgtat ataaaattga
    19441 tgacccaaat ctacctttag tttcaattca agaccgtgca aatgttgcac gaaaaaataa
    19501 taaaggaaac attggaaatc atccacttta tacatgtgtt ttttatagtg atttagagcg
    19561 tttaaaaatg attaaagaaa aagaaatgga aaatagaatg gaggaagcat taaataataa
    19621 cgaatttata gtatatcttc agcctaaaat aagcctcaaa gataatacta ttgtaggtgc
    19681 agaagcatta gtaagatggc aagacccaaa taaaggtctt ataccaccag acgagtttat
    19741 tcctttcttt gaaaaaaatg gttttattac aaaactcgac cactatgttt ttgaaaaagt
    19801 atgcagtatg ataagaaaat ggatagataa tggagaaact ccaatacctg tttcagttaa
    19861 tttttcacgt gctaatttaa ataatataga ttttttagaa aaatacagaa tgcttcgtaa
    19921 taaatacaac attcctgcta agctcttaga aattgaatta actgaaacac ttgtatttga
    19981 aaatctccaa aaattaatta atataataga ccaaatccat gaagaaggtt ttcaatgttc
    20041 actagatgac tttggaagtg gatactcttc actcaatatg ttaaaagaaa taaaagttga
    20101 cacattaaaa cttgaccgtg ctttttttag ctcacctaat gcagataata ttgctgaaaa
    20161 tcatgtaata gaatctatag ttaatttggc aaaaaaatta aatatgaata gtatatcaga
    20221 aggtgttgaa acaatcttgc aaatggatta tcttaaaaaa attaattgtg atatgataca
    20281 aggatatgtt ttttcaaaac ctctacctca agaaatattt gagaaaatga cttttggaaa
    20341 aaaactagaa gaaaccagta tggatagttc cgtttaaata aaataaaaaa cttgtctcta
    20401 taaaataatt ttaatcattt tataaagaca agtcttttta ttttccaatt taattttatt
    20461 ttctaaattt cttacactcg gcttgtttta aattcccttt ttaagaataa taatacaatt
    20521 atcatagcaa taaaatctgc aactggctgt gccaaccaaa caccatctaa attaaattga
    20581 attggaagta caatgattaa tggtataaat aaaataaatt gtcttaaaag agttaaaaac
    20641 attgaatgtt taactttact tatacactga aaatacacag gtcctacaat agaaatcccc
    20701 attataggca atgtaattag atttaggctt atacctctta ctgctatatc catcaaatct
    20761 gaatctttat taaatatacc tacaaatact tctgggaaaa cttgtactac taaaaatcca
    20821 aatgacaata tgacaactga cactatgata gataatatta aagttttctt tgcacgctca
    20881 tattgttttg caccataatt gtatgatatt atagtttgca taccttgatt caatccaaac
    20941 acaggcatca taaacatcaa taaaatagat gtaagtgctg tcatagctcc aatagctaaa
    21001 tctccaccat aaacctttag agaattattt gtaaacatgt gagttatact tatagctact
    21061 tccatagcaa aaggtgtcat tcctattgca aataccttct ttactatatc tttattcaat
    21121 tttaagttac atttttttag ttttaaattg gacttccctc ttataaaata atgtattacc
    21181 caaaagaata ctactatttg acagagtact gttgctatag ctgctccttt tatacctaaa
    21241 ttaaatacaa atataaatat agggtccaat atcaggttta atacacatcc tacaatcatt
    21301 gtccttgctg ctaattttgg attaccttct gccctaattg cattattaag agaaaatgca
    21361 actaaattaa atatacttcc aaccaatatg acactcatat agtcttttgc ataaaatatt
    21421 gaatctttac ttgcacccaa aataaaaagt atatcttcta agaaaactaa tcctaatata
    21481 gttataatta aagagataat tatagatagt gtcaaagcat tacctaatat cttctctgct
    21541 tcttctctat ttctttcccc taactttata gacaatcttg tgctagcacc tactgatacc
    21601 aacattccaa aagctattat tagagtaaat actggcatag ttacaccaag acctgcaata
    21661 gctatagagc caataccttc catagaacca ataaaagctc tatctactac attataaagt
    21721 gaagttacca tcattgctat tattgcaggt atcgaatacc taaataataa aatccatatt
    21781 ttttcatgtc ttaatgcttc ttgattctcc atgttgtcac catttacacc atgtcataag
    21841 ttatacaaat tggtttattt gttcttgggt ctgttgctat ttctgcatca atattaaata
    21901 attcttttag attatccttc gtcataacat catatgcatc accttcacaa actattttac
    21961 ctttcttaat acctatcatg tggtcagcaa atcttgctgc attattaagt tcatgtatta
    22021 ccatgacaat agttcttcct tgttttttat ttagttcatc taataatttt agtatctcca
    22081 attgatgtgc caaatctaaa tatgttgtag gctcatccag taataatata tcagtttctt
    22141 gtgccaaagc catagctatc catgcccttt gtctttgtcc tcctgataaa tcttccatat
    22201 ttctatcctt aaattctgca attccagtaa cttctaaact ccaatttaca atctctctgt
    22261 cttctttact agaattacca aatccacttt tatgaggaaa tcttccataa gaaattaatt
    22321 ctgaaacggt aagaccacta ggagcttgag ggctttgtgg aagtacagcc atatcttttg
    22381 ctatttcttt agacttcttt ttgtagatgt cctctccatt tatatatatt ttcccactat
    22441 tagggctaat aattctacct atagttttaa gtattgtcga ttttccacaa ccattagccc
    22501 ctatgatggt agttattttt ccttttggta tatttaaatt taaatttttt ataatatctg
    22561 tgtttccata tgatacattt agattcttag tatttataca gttcataaca acaccctttc
    22621 ctaatcattt accaacatta aataaataaa gtacggcact cctattatag aaactactat
    22681 acctactggt atttctatag gtgctagaag atttcttgat atagtatctg ctattaaaag
    22741 taataatgtt cctatcaatg ctgatactgg tattaatctt ttatgctttg gtcctattat
    22801 ttttctacct atatgtggag ctattaaacc taaaaatgaa atactacctg ctactgctgt
    22861 cgatacacca gataaaatta ctgcatatat tataagtctt cttctttgtt tttctacatc
    22921 tacaccaaga cttatagata cttcatcacc caaatttaaa acatctatat atttagattt
    22981 ataaatagtt atacccataa aaatcactat aaatggaagc acagctatta catatttcca
    23041 actggttccc caaatgcttc ctgatgtcca tgccataacc ctattaaatt cctgtgttgt
    23101 aaatttcaat tggaatattg tcaaaattga agtaaaagct atgtttacac ctataccaat
    23161 aagtagtaat cttgatgaat ttataccacc tttccatgca agagaatata taagaaatgc
    23221 tccaaataaa gctcctataa gtgcaacaat aggcattgta aatacagtca agttactcat
    23281 accttcatat acattaccat tcataaggta tatataaact actacaaaca atgcagcacc
    23341 tgaatttatt cccaaaattc cagaatcagc taaatcattc tttgtaactc cttgaagtat
    23401 tacacctgct gttgataatg cagaaccaac caaaagtgct attactattc ttggtaatct
    23461 taatttaaat attgcaattt catgattacg ctgaccctgc cctaaaaaag tctttataac
    23521 atccattggt tctatagaaa atgagcccat atttaaactc aataaaaaag tgataaaaat
    23581 aagcaccatt aaaattgata taacaagtaa tgttttagaa tttattttta taatattttt
    23641 catagtacct atttctcccc ctttctaaca aggtatataa atattggcac tcctataagt
    23701 gctgttatag aacctactgg tgtctcatat ggaggattta tcatcctact taatatatct
    23761 gtatatacaa gcaatacagc tcctaatact aaagagctcg gtattatata cttataatct
    23821 gaacctacta ttcctttagc tatttgagga actataagac ctataaaaat aatattacca
    23881 gacactgaca cagatgctcc agtcattaat attacaagta ctatacatat aaatctaaca
    23941 aagttagttt tttgtcctaa tcctattgcc acttcttctc caagacttaa tatagttatt
    24001 cttggagcca taataatagc taaaataaat ccaataccac cagctacaaa tagcaatttt
    24061 ataccttccc acttcactcc tacaagccct cctgatatcc agaaacttaa ttgttgagat
    24121 aggttaaaat acatagatat tgctgatgcc aaagaaatta gcaatgtacc aagagcgact
    24181 cctgcaagag ctaattttac attattaact cttcctcttg atttagaact tataaaatat
    24241 ataaataatc cacttatact tgctccaata aatgcaaaca tcattacact aaaacttcca
    24301 tgtataagtt gaggaagttt tttttgaagt accagtgata tcgaaattgc gaatgtagct
    24361 ccttgtgtaa ttcctataac agatggttca gctataggat ttctcgttat tccttgcatt
    24421 attgccccag aaactgctaa aaatcctcca acaagtgcag ctgctattgc ccttggaagt
    24481 ctaacatcct ttactattct catatttatt ccatcttcca tttttatcaa actatctata
    24541 acagttgata gattcatatc ttttgcccca atagttatgg ataatacaat tccaaataca
    24601 agtacaacta tacttactaa tatcaacaaa taagttatat tttttttact cagcttagtc
    24661 aattatccta cctccttttc ccttttaatc gtcagtataa tatcatctat taagtatttt
    24721 aattttaaga tttattaaaa ataggtgtga aaaatgaata tcattatctc acacctacta
    24781 agttaagaat tactttgtta attcattttt aactgattct aataataact cttttccaat
    24841 tggattgtat gattgactga aaaatggagc agcatcaagt attgttacat taccatcttt
    24901 tactgctctt atttgagccc agatagcact attttctaaa tcttttttat ctgcttctgt
    24961 agcaattaca actatatggt ctgcatctat atctgttaaa ccttccatac ttaccattgg
    25021 tagtgttatt ccatcctgtt ttggcatatt cttaggttta gctaatttca tatcatcatt
    25081 gattagagta cctattccac catcactaaa taccataaat tgacctgaac ttgccaacac
    25141 tggtaaataa gttttttctc cattcttttc tataacttcc ttacctaact ttgtagcttt
    25201 ttcatcatac ttctgtagcc aacttttagc ttcttcttct ttgtcaaata actttgaaac
    25261 atcagttaac ttgcttctcc agtcatttgc ataatctttc atcataacta caggagctat
    25321 ttcttttaat tggtcatata ttttttcttg tctttgactc attattatta aatcaggatt
    25381 tacttctaat atagcttcca tatccatagt atccatcatt gagtgcccaa ctatctttac
    25441 acctttaagc tcttctctta tgtaacttgg taatttatca gtttcatatg agtctacatt
    25501 tgctgttgca acaggcttat aacctgctaa taatagttct tcactacttc ctgatatatc
    25561 aactattttt ttaggatttg atggtatctt aacctctcct ttaacagatt gtacaactct
    25621 tgtctctgat ttatctttat cctctgtatt cttatctgaa catgctgtaa caagtactaa
    25681 cgtagttata atagatataa atattgcaag tgattttatt tttttcatga ttacttctcc
    25741 tacttgttta ttatacttac atgatattga ttatcataag cacatattta ttatagcatt
    25801 tttctatttt tagtcaatat tattttgtaa aaggataaaa attcctaatt aatcttaatt
    25861 atatatagct tagataaggt tttcttatat taaacagtat ttttttaaag aattggacac
    25921 aaatacaatg acttttcagt taaacaatga taaaatgcaa tttatagata atgaatttag
    25981 taaggaggat tcaaaacatg gtacatttag tatattgtga taatgcagga aaaaaaggag
    26041 aaaaggtctt agataaaatc ttggctggaa caaaaacaat ggttattaga ggtgctgctg
    26101 gtagaaaaat accacatagt agagtatttg aagatgagtt actttatttt atggaaaaag
    26161 gaactgcaaa aatatctgca aaagccactg ttaaaaaggt agaaaactat gttaaattaa
    26221 cagaagatga aatttctaaa attttaaatg aaaatcaacc aaaattaaat ttatctgaaa
    26281 agcaaaaagt tcgttggcat aaaaaatgtt tatgcttagt tgaatttgaa aatgttgaag
    26341 aaataacacc tcttgatttt gaccatcaag gaaatatgga tgattggctt attgttgaaa
    26401 aaattgaaga tgtagttgtt ggtactagta taccttacaa ttatgagaag tctaaatttt
    26461 aaagtatcaa taacataata ctatattgct aaactctact taaataaaaa aagagtgcat
    26521 ttaataatta taaaaattat ttttatacac tcttttttaa taataatttt aaattactta
    26581 ctttctaatc tttcatatac atctataaat tcttctgcta attgttgaaa attcatagct
    26641 gtcattaaat ggtcttgtgc atgaataagt ataacactta tttcagtttt attaccatta
    26701 gcttcatttt gtatcaattc tgtttggaat ttatgagctt tatgaattga ttctttcgac
    26761 ttttcaatac attctctagc tttatctata ttcccgctct ttgcttcttt tattgcttca
    26821 aatgctagcc ctttcgcatc acctgcaaat ccaattattc caaaagatat ctctatcatc
    26881 ttctcatcca tttattcgac ctcctaaata tctctatagc ttgatatgac taatccattc
    26941 ttttctaaaa attctttgac ttttttagat gtaagtatct tgtgctcttt cgttctatca
    27001 atagcataag atgtagaatt taaaatataa tcatctaaaa aagctgggtg agacataata
    27061 tccactacat catacttcat tatttcgtct atatttttta taaaatattc ttcacttaca
    27121 ttttccttat aaaaactatc tattaaagga actactttag aatactctaa attatattca
    27181 aatccacctc ttattggaag attatacttg gttacaatct tctctattac tggctttaaa
    27241 cttaataaag tatggatatg atggtgacta tctaaatgag atatatctat tccaagccct
    27301 tttaccctat ctatttgagc acaaagttct ctataaatct catcacaatc cattttttca
    27361 ataatttcgt ctgtaatcct cctaataaaa aaaccgtctt tatcaacaat agtttttaag
    27421 ttagataata atggtctacc acaacttaaa gtcatatgaa ctccacaatt taaagtttta
    27481 ttttctttaa gtaagcctac tccatgttct accccaggca tatttgccat catagaagta
    27541 gacctaacta taccattatt atgagctgaa attattccat agttcacagc ttcacaatat
    27601 ccaaaatcat ctgcatttat tataatttta gtcataccat aacctacttt ctatagacaa
    27661 ctatctatta aatctaggaa gataatcttt atgagcttcc aacatttcgt ctaatatagt
    27721 ttttgctaag tcatcagatg gaatcaatgg gtttatacaa agtgccaaaa gagcagattc
    27781 ataatcgcca tatacagctg ctttagctgc caatacttca aatgatttga tttgacttac
    27841 taatccatgc acagaatctg gtaaatatcc tatacttatt ggttttggac cattttttgt
    27901 tattacacta cttacttcta ccgcttgttc atctttaaaa tctcttatag aacccttatt
    27961 taatgtatta actacttgga tatctttttt gtcgttgtat atagaactta ttaaattaca
    28021 agcagcatca ctatagtaag cccctcctct tttttcaagt tgaggtggtt ttacatctaa
    28081 tttttcatcc ttatataatt caaataattg ttcttccaat tctttaacta cttgacctct
    28141 agcttttccc tctttaaact ctctcaactc atcctcaagc atttctttag ttttatagta
    28201 gtatctatga tatggacaag gtattgcacc caaagatttt acaaattcag cattaaaatc
    28261 aattgccttt atattttgca tacttatatc tgctttgaca aatttatcaa ttgcttcttt
    28321 tgtaacatct tctccatcta aagatacatt tagaccataa accatatgat taagacctgc
    28381 aaaatccata cttattctgt cactttctac attaaatagt ttggcaacat cattttttaa
    28441 atgaattggc acgttgcata gacctatata tcttctaaaa ttagtatatt tgaatacagc
    28501 ctctgttatt attcctgttg gatttgtaaa attcaccatc catgcatttg gacataattc
    28561 ttccacatct tttattatat caaatataac tggtattgtg cgaagggctt taaataaacc
    28621 tccagcacca ttagtttcct gccccataac tccatgagat aaaggaatag tttcatcttt
    28681 tattctcgca tctaaaagac ctactctaag ttgtgttgtc acaaagtctg catctcttag
    28741 agcttctctt ctatctaaag taagatttat tttcatatct actccagctt tttttaccat
    28801 cctcttagct agatttccaa ctatctctaa tttttctttt ccagcttcta tatctacaag
    28861 ccataattcc tttacaggta actcttcata tctatttata aaaccctcta caagctcagg
    28921 agtataactt gaacctcctc caattgtaac tatttttagt ccctttttca tctcattata
    28981 ccatccttac ctataattta atatactcta caaaacccca tacatttatt taaaactcta
    29041 tacatttatt taccgaaata aaactaccta gttgttaatt ttcaatttat tagcttccat
    29101 tttttcagac gctatgacaa atggaatata tattaatatt gataatatta aattaaatag
    29161 tgctaaagct ccaccagtcc agtcacctgt agccattgct ccacctaata taggaggtgt
    29221 tacccaaggt attttaggta aaattactgg tgctactaat ccaaaatcta ttgctaagta
    29281 tgatacagca ctacatatta ctggtgcaag tacaaatgga atcataaata taggatttaa
    29341 aactattgga agtccaaata tcaatggttc tcctatgtta aatattgcag gtggaccacc
    29401 taatactatc atctctttac gtcttcttcc agctattaat aaagctacta ttaatcccaa
    29461 taccattcca gaaccaccta aatatacaaa tgcatcaaag aatgcacctg caagtacatg
    29521 gtatccttcc gttgctcctg cttgagccaa ggcagcattt tctccaccta atttcataag
    29581 tatagtttct gtaaaaggaa gtgctatatt tgcaccatga agtccaacag tccaaagtat
    29641 atgaattata aatgcaataa gcattgtaga acctagacta tcagctacat ttgatagtgg
    29701 tgctcctaaa taagtattta aaatatctgt taagaaactt ccattagaaa gcatttttat
    29761 aaatattcct attacagtaa atatcattat agttaacatt cctggtatta actttgcaaa
    29821 tgatcttgaa actgctggtg gaactccatc tggcattttt atagttaatt tctttacctt
    29881 agataatctt acaaatatct cagttgataa taatcctatt aatatagaag agaataaagc
    29941 tgctgtacct aagtaggttt gttgtatcat tccccatcct tcaactactg tagttcctcc
    30001 ctcaggaact attttaccaa tttgtggagc cattataaaa aagatagata aagctataag
    30061 cccagattgt aacccatcac tctcataaga ttttgctaga aaataagcaa cacctattac
    30121 taagaatact gccattgtac ctattgctcc ccaccaaagg tcgcctccaa atgtggtcca
    30181 gttttctcca aatatacttg ccatcaaatt tttgtatgct tccaatggta agttatttat
    30241 caatgttccc aatgcaccta ccatagttat aggtatcatt actataaatg catctcttac
    30301 tgctactaag tgcctttgag ctcctatttt agcagctaca ggcactatat atttatccat
    30361 aaatgacatg aatttttcca ttttacatcc tccagtacaa ctttattttg aactatttaa
    30421 ctctacagct ctatctaaca cagcttttcc attacatctt ccataatcca tcatatttat
    30481 aacttctact ggaatattat atggttttgc catttcagtt gcttttccta atacatatct
    30541 aacttgaggc cctaaaagta agacatcaca attttctatt tcatttttta agttcacttc
    30601 tgatatagcc catatttttg cttctatacc gttttccttt gctgcatcct ccatttttgt
    30661 aactaataaa ctagttgaca ttcctgctga acaagctaac attattttta tcattttttc
    30721 ccctccaaat tagattcatt aaatattttt taagtcataa gttttttaaa ctatacattt
    30781 aaaatatgtt tttctattaa ttttttctta atgtatatat cttattttta aatgtatata
    30841 catttaattc ttgatattat tatataccaa atgtatatac atttcaagaa aactttttca
    30901 ttttatttaa attttattcg acaacagcat tcaaagttaa tgtatatcca tagtgatatg
    30961 tgtgtgagta ctcaaaaatc tcactatttt gtaacttaca aatttggctt atatataaaa
    31021 gtggctctgg ttcttctaat tttagattat ccatacactc ttcattcgat attacagctt
    31081 gtacttctct ctctgacatg gctatcttgt atccacacac ttcttcaaca aaattataaa
    31141 gagaattttc acaatgagtc ttatttaaat ttggaaataa cttaactggc atataagtaa
    31201 tcatatatga aactcttaca tcattagcta atcttactct ttttatttcc caaacatttt
    31261 cttctaaact tatattcaac ttacttgata aattttcatc tgcctgaact atttcaagag
    31321 ataccaatat attagatact ttatagcctt tactttccat ctctttagta aatccactta
    31381 cagacgatat attatcatat atattatttg caataactat actacctaca cctctttgtc
    31441 tagttatata gccttcttta actagattat taagtgcaga ccttacagtc attctagtta
    31501 cattaaattc ttcactcagc tgtttttcag aagggattaa atccccttct ttcaaactgt
    31561 ctgaatttat taactctcta acatgatttt ctataacttt ataaattggc tctttcattt
    31621 aattcactcc ttattaaatc ttttatataa taagataatt ttatatacaa acaaagaaaa
    31681 tgtctataca tttaagataa tttaaatttt attcagaaat cttgtacaac tttccgagtt
    31741 ttaataaaga tataaataga cttatcatta atataccttt taatatactt gataaggtta
    31801 tactccacca tacaccattt agacccaaca tttctggtct agatataaag taagccaatg
    31861 gtactcttgc accagtcagt atagtaatta taatagaagg tatataggtt ctccctaatc
    31921 ctttgaaagc tcctgttgtt attatttcta aacacataaa aaattgagaa tagcctaata
    31981 ttttaagata aactgctcct ttttctattg cctcactttc atctataaaa atagaaaata
    32041 tactctctcc tgcaaacact aatactaaag tagttattat accaagtaca gaagatacag
    32101 ttatagctat tttgcaacct ttatttattc tagaatactt cttggcacca taattttgtc
    32161 caacaaaact gcctaatgca actgatagcc cttcagccgt catccaggaa attgcttcta
    32221 tttgtgagcc tactttttgt actgcaacag ccacaggccc ccatgatgct actattactc
    32281 ctaatagcat tgagaatact gtaaacatac cactttgtat tgctataggt aatcccaatt
    32341 tatacagaac tttataatat ttagtctcta tttctttaaa tagtcttaat ttaaaatatt
    32401 cttctttact tttaactatt atatatataa aacatgtagt aactactatc tgagcaaata
    32461 cagttgcaat agcagctcct gcaacaccaa gttttggagc aaatccccat ccaaaaatta
    32521 atatagggtc aagtataata ttagttatta atcctactgt attaatacga aaaggagttt
    32581 tactatttcc aagaccattg aaaattgcag taaatactgg attaataaaa taaaatacca
    32641 tacctagagc tactattatc aaatactgtc tagacatggt tataacttct aagtctccta
    32701 atctaaaaaa acctatcaat tgtttattaa gtactattaa agaaattgta tatattattg
    32761 ctagtataat atttatttct attgctgact tcatatatga tttagtagtg cttatattat
    32821 ttgcaccaat actttgtgct acttttatct ctccacctac ttttgaaatc ataataaatg
    32881 ccattgcaag ccatggaaaa aaaccagctg ttccaactgc agctactgct ttacttccgg
    32941 ctttaccaac ccatatcata tctatcatgt tataccccat ctgtataaat gaagtcccca
    33001 ttattggaag tgatagctta agtaattttt ctgtaattct tccttctgtt aaattaagtc
    33061 tgtctttcat tttccacctc ttttatatta aatttatttg cttatatagc tagattaatc
    33121 attttatttg attgagttca ctatccttca atttatatta tcatatctca ggattgcatc
    33181 tcaatcatac ttatgtttaa gatacagtat tttacctatc tatgataaaa ttaatactta
    33241 tgaatataaa tctagccatt tcatcaatac atattctaac ctttaactta acttcaatta
    33301 agtatacata tcgtaaccaa ttagaatatt ttatacggta tcttccatta ataaacaacc
    33361 aatatcaatg atttatatat aattttattt atacataaaa tagtatacta taataataaa
    33421 aaaactatat ttgaatgctt taagcatgtt tactaattgt aatttccaca caaatttgat
    33481 aatatatgaa tatattatgg tgaaatttat agatatatat taattatggg gagattgtgg
    33541 gaggttcttt tcacaagaca tttaagctat gaaaataaat aaaaaattca atagagttga
    33601 tatgcaggtt tcaatactta ctgcaattat tgtaataata tcttcctcat gtgtatattt
    33661 ttttaattat acactaactt ataagagcat gatatactct ttaagtgaga ggtcaaaaca
    33721 tatctatgaa tatgtagaaa gaaatattga taaaaatacc tttactgaaa ttaattctaa
    33781 agaagaccaa tcaaaaaagt cttataaaag ttctaaaatc cttttagaat ctgtaaaaaa
    33841 tactactgga gtcatgtatc tatatactgc taaaaaaaca aaagatggat cactagtata
    33901 tgttgttgat ggtttaaatt catctaggag tgattttaga aatgctggtg atttgataga
    33961 aaaagagatt tggggagacc ttaacaaagc attagataat catatattgt tacctaaaaa
    34021 gattaaatca acatcttggg gatacatatt tatatcgtat tttcctattc acaatgatgt
    34081 tggtaaggtt gttggagtaa taggaattga atttgaagca aaacatcaat acaatacatt
    34141 taaatttata agtatagtta caccaataat agcattatta acttgtctaa tatcagcatt
    34201 gattgcagtg attctattta aaagaatatc taatcctaca tatactgatt ttgctaatac
    34261 agattattta acaggcctaa aaaatagaaa tgcttttgaa atagatatga ataacttaaa
    34321 caattcaaat ctaaagaatc taatatctat catatcaata gatttagacg gtttaaaaaa
    34381 gattaatgat aaatttggcc atcagacagg agacttatat attaagcaag caagtaaaat
    34441 tatacaatat gtaataaata aaaaatatat agtttatcgt attggaggtg atgaatacat
    34501 aattattcta aaaaatttat ctcacaaaga aataaataat attataaata atattaattt
    34561 aaaaatagtt gaagaaaact caactaatga attaaaatta tcaatgtcta ttggatatgc
    34621 tatttttgat gaaaaagtag atgtttcttt atttgataca tatcgtcgtg cagattctca
    34681 aatgtatgat aacaaaagga aaattaataa acaatatcaa taataaattt aaaaagtcta
    34741 ttctttaaat aataaatcac aagaatagac ttttttaaat ttgtgttttt ataagataaa
    34801 ttatttaatt aaagtttgtt cttttttcta aacgattctt tataaattca tatattactt
    34861 tcactaatat atttgtgact aatattaaca cagctagtga tgctgcctgt gcagtactcc
    34921 ccttatcatc tagttgtaca attgatattg cagctacttt tgaacttgca gtatatataa
    34981 aaactaatgc tgatattgtc accatggagt ttaggaaaaa gtacataaag ttctctaaaa
    35041 ctgctggcaa acaaagtggt atagttacgt tcttaagaat tgatgcgctg tttattccca
    35101 ttgatttagc taccatatcc aattctttat ctactttctt aatagcagta gtagctgtta
    35161 taaatgctac tgaaaagaaa tgaactatat tacatataac cattataagt aatgttccat
    35221 ataatccatt aaacaaattc ttaatgtata ttgtatccat aaaattaaac tctaatttat
    35281 taaaaaataa tacataagct atacctaaaa ctaatcctgg caatgccata ggcaatgtac
    35341 ttaaaaaata cccaaatgat tttaaatatg gagctttttc tgttttttca ttcaaatatg
    35401 caaataagaa aacaaagctc gtccctagaa tagctgtcaa tagtgacatt tttattgaat
    35461 ttataaatgg tttaatccca tcaatactgt ttttcataga aaaatgttcc agtgtcagtc
    35521 ttaaatcata tggccaaact gatattaatg aagataagat tacagttaac attacagcta
    35581 ttataccaaa tgcaataatt cctacaaccc ctcctaaaat actatctctt aacttattag
    35641 ttttaacctt atatggaatt gactttgaag ttatatatga attttgattt ttttcaattt
    35701 ttttagttac tataaacgat attattgcag gtattaaaag taatattgat acagttgctc
    35761 ccattggcat attctgttgc cctataattt gcttatatac atctattgat aatacattaa
    35821 actctcctcc tatcaccttt ggagctccaa aatctgtaaa acataatgta aacgatacga
    35881 atgcagaact tattaaagag tattttatac ttggtattgt tatgcttata aattctctta
    35941 tcttgcttat ccccatagta ttactagctt catatagtct ataatcggtt gaacttagag
    36001 atatataaag tatttgaaat gattgaggaa atacatatat aatttgtgcc aatattattc
    36061 ccactgctcc atatattgga acatgcactc caagtaaatt agttaccaaa ccttgatttc
    36121 caaataaata tactagacct attgcatgca tcattgttgg agcaaacata ggaaacatag
    36181 ctaatgattt aaaaaaacct ttaaatttaa tctttgttct agttaatgca tatgcatata
    36241 ctaatgcaag tgttagtgat attacagttg atataactga tacaaatact gtatttttta
    36301 gagaatttaa tagagattca gaagccaagt attcttgaaa gttttgtaat cctacaaaga
    36361 ctccatcttt atctaaaaaa gcctgtacaa atagatatat tataggtgct aataaaaata
    36421 ttactaaaga cataactaat actgtaagca tacatttttt tatatctaaa ttcatttttg
    36481 atttaagact tatactttta gaacttatag cattattatt catacactta tgctccttta
    36541 acttttggat actttaaata gtatttttcg tctatactta tttttacaag gtcaccttct
    36601 actaaattta aattaaccca ctcttttata gaagcatcac ttattatgaa attttcattt
    36661 aatttatctt ttatttcaac tctcaataaa ttccctctaa actctatatt tgatattatt
    36721 ccttggtagt tttcttttgt cgatttctct atttgaacat attctggtct tacagttaat
    36781 atagaatctc cattatcaaa acagtttgta tctcctataa attgagctgt aaataggttt
    36841 tgaggatttt ggtatatttc ttctggagtc cctatttgca ttatatctcc tccatttaga
    36901 atagctattt tatctgccat agttatagct tcttcttggt catgtgttac cattattgtc
    36961 gttatattaa gttctttttg taatctttta atgtccattc taagcttgtg tctaaccttt
    37021 gcatctaatg cggacattgg ttcatctaaa agtaaaaact ttggttcaag agctaatgct
    37081 cttgctattg caatcctctg ttgttgccca cctgataatg ctttaggata tttatgagct
    37141 tcattagtca atccaactgt ttcaagtact tccttaactt tattatctat ttttcctttt
    37201 gaaacttttc tctcttttag tggaaaagct atattgttat aagcagtcat attcggaaat
    37261 aatgcatatg attgaaatac tataccaaaa cctctctttg atggctctaa atttgtaata
    37321 tctttatcct ggagaattat agttccgcta tttacatctt caagacctgc tattattcta
    37381 agtaatgtag ttttaccaca tccacttggc tattattagt tagtccaaat aaataaaata
    37441 cttataacaa ttgaaatacg cgatatacac tgaacctccc atgactaaag tcacagggtt
    37501 cctgtttcat agaatttcgc ataattaaat gttagttcac aatactattc taacttacct
    37561 tgacctttaa atactctgtt cctttttagg aataaaatac tattcatacc tataaattta
    37621 ttcaattttc aaacaatctt gttgaacaat aactaattct attgtattat tttagttgta
    37681 gaataaaact aaatcggcaa aactagagaa atttagtgac gcaaagctat agggactaag
    37741 acttatataa atatcttatg agttatgtca gccagttgcc aaagagatat tgttcttttt
    37801 gtttttatga aagtttttta gggggataat aatttatatg tttagagata aaatggataa
    37861 atgtacacat gtattgactg cttatattgg tagttcatat gattattgtg attttataga
    37921 tacacagtta gatgatttta tactagagta cggagaaaaa gttgtggaat cttgcttgca
    37981 tcaagtaatg gtattggtaa gtaagtataa ttagatagac attgatttct agagaaccct
    38041 ttttagtttt atctactttt aaataatgat atgttaaaaa attaattaaa atatctttgt
    38101 aagaaaggat aataatataa atgtgcttta agacttatat actaaaaaga gttgtaaata
    38161 acaaacaact agaaataact cgaagttttg aattagataa tctcatttgt actgcaacag
    38221 agattttgaa agatgatgag attgatttaa taattattga tgaaaaaaat agtattgttt
    38281 ggagaaatga aaaaagcact ccccagcaag agaatgctta gttatagcta tagaagtgta
    38341 ctacgaatac acttctattt ttttattata tcataaatta ttcatagtat taagtaaaaa
    38401 tagagctaat acaatcagtt ttaaaatagc ttgaatagct ttcttgagtt atttaccttt
    38461 gcataaatta ttgaatattt gaaataaaaa aagataggtt tacccctcat cttcaatcaa
    38521 attaaagtct atatttatag tatataattc tttacttcta tccatttcaa atattgatat
    38581 ttccatatca tatgatttat tataggattt atcatatata ttcttacatt taatattaat
    38641 tgtacccgcc ttaatatttt tcctaatata tataccatct tcattatttt ctctaaaatt
    38701 atctataagt ttactagata attccctaat atacatttca gtatatgcgt ttaaacctat
    38761 ctcaacttct tgtaaagaag aaatatattc tttctcgact ttaatatttt cgttttcatc
    38821 aaattcatca aagaaattat tacatacttc taaatcatca tctgttaaat attcagtttt
    38881 aactatattc agaggttttt cccaaaatac ttctatttgt attgctgctt ctttccctac
    38941 attcacaagt gttaattcta taatatctga acatcttggc acttcgcttg atgtcttaat
    39001 ttcattaaac atacaaggac taccataagt tttatacaaa tatgcatttt tcttaatagg
    39061 aataacctta ggctctcttt ccatagatat actttctttt aattcttcat tatctttttt
    39121 agccatttct ctagttatca atatagcacc taatgttgct aaccctccaa atataccacc
    39181 taaaaaactg ccccaaaaac ttaaccactc accatctgtt gaattatgtg tttttatatc
    39241 ccaatataac accctattta ttaacgatgg taagccaata catataataa gaattgctat
    39301 tacacttata aatatggtta gtatcttatg cttttcaatc caacttttat ttttattgtt
    39361 tatattgctc attactttcc ctccgttcta taatatatat tttaccattt tgtacaaaat
    39421 ggtaaaatat attatgggat aaatattatt tggatataaa ctttcctttt gtattaagat
    39481 attatcaatc tcttatttta tctataatat gttattttta agcctaaaaa agagataact
    39541 attttaatcc tagttacctc tttttatgtt attttggcca tatagatata cctattgtaa
    39601 tagccattgt agcaattcct attatagtag ttatacataa tgcaataatc catttattag
    39661 ttgaatcaat tctatcttct atacctttta tactattctt tatttcactt acatcctttt
    39721 ctgtcacctt tttatgttcg tttatagctt cttttaaatc gctttttaac tcaattcttt
    39781 ctctagctaa atcatttttt agttctattc tatctttgtc taaatcattc ttgtattctt
    39841 taaaaatacc ctttatgtca ttaaattgct tatctatact ttcttttact tccttattat
    39901 tttgatgtac tcttttttca gtctctaata ttcttttttc agtttctagt attctttttt
    39961 cttcttcatt catattacct acctcctctg aagtagtagc taaaaaccaa ttatctccaa
    40021 tacatttatt tttctccatc aaagtactat ttaaagtatt ataatagtct gtatatttgt
    40081 tgattttact tttatccttg ttggaattaa actttattac tttttctttt tctttattat
    40141 attcaccctt cataactatt cttcctctat catagactct aaatgttcaa ttattgattg
    40201 tatttctgat ttagatagtt ctaattccaa agatttttta tcatttctaa atagtttcaa
    40261 aataaaatca ttttctctag ccaaagaaga tatagaatat aagccaattg gattgattct
    40321 ctgaatatat gagttatcta atatatcata tgtactattt gaaaaagtat acaaatcatt
    40381 tttaaagttt tggcttatat ttacattttc accttcatta taaaagtctt tcagtttaat
    40441 tccatactca cctataaatt ctgggtcttc tcccaaaatt tcatttgctt tagctttaaa
    40501 ttcatgaata caatgtggcc aagttggcat ctgcatatat aaattaagta atagtattgt
    40561 cttttcaaat attttgttat ccttttcgta tttttttata cagttaggaa aatacgctac
    40621 caaattagtc ccattttcat aagccatctt aactccccct aaaataatat tatttaatac
    40681 tattctacat tataattact ttcattgcac tattattttt tattcctcct cctaccactt
    40741 attgatatat actcaactgc tcttcatata cctgattttt taaagtttgt agatgactta
    40801 tggttatatt taatatatca ttttttattt tataaattgt tgtgatactg tcataaaatt
    40861 gtagtcaaaa tgtaaaatat attaactcta ttgattttat ttatttataa actccagtgc
    40921 tttataaagt gtatcaaatc tatcattacc ctttatcata gtgtatcttt ctttagtcat
    40981 agaacttatc ttttcacatg ctccaccacc aacgacatat aaattttctg tctgacctgg
    41041 tacgtaatct tttatatcac atatcagtat ttttccatca ttatagcccc aaccaactac
    41101 agttgcaggg attttgtcaa cttctccatc ataaacgatt gtatgtttgt acatgatttt
    41161 tccctcacca ttctctttat tatctattgt cttatttaaa ataccttctg ctattaactt
    41221 agcaactatg tctttatgtc taatataata atctgtatct gctttactat ctacgaaaca
    41281 tacttcaatt aatattgctg gtgcttttgt atgactaagc caataaagac ccctcacatc
    41341 tgattttgca cccctatttt taaatacagt tgataatttt gaattaactc tttcggcata
    41401 taccttacca ttgttagttt tgtatattgt ctctgtaccc ataggattta gagttgtttt
    41461 atttgcgttg aaatggattt gtactgctaa gtctacattt tgcctatttg caattttaca
    41521 ttgttctgct aagtagttat tagatttatc tacttttcca gtatacacaa tagctccacc
    41581 ttgtttcaac catttaacaa ttaaatcagt taaaattcta ttttcttttc cttcgtctat
    41641 atagccagtt gctcctgttc cttttccact taaagtgtgt cctggtacta ttgctatttt
    41701 cattatttat caccatcctt caactgtttg taaacttgat ttgcccctat tgcaactccc
    41761 caacataaaa ttccttgtaa aattgatgaa ggattaaatc ctaacatcca tattgaaaat
    41821 ccaattccta tcacaagcaa tatgattgga atgtatttat tatctaactg tttgtatttc
    41881 ttaaatccaa atcctaacac attaagagca actactaata aaagcagttg ctctggtata
    41941 aaacttatta aattatccat atcttaacct cctaattaat taaaatattc ctttctgtat
    42001 ggcaaatata aagaacccta ctaaagttgt aattataact cctacaagcc acttgagtac
    42061 tcctgtcaga ttttttatat cactacatag gttttgtatt tgtatagcaa actttgcttg
    42121 ctcaatctcg attctatcaa tttgtttgcc gtgttctttt actcttgttt caagtgtact
    42181 tattttttct ttcacaagtt cttcattcat gaaaacctcc tattgctttg tattaaaaaa
    42241 agaacattac ctattttgta agttctgctc cttctactac ctcactatgt tctataatgt
    42301 agttttcaac tgccatcctg tactctgtgt tagtaacatc atcaagttca aatactctat
    42361 tttttagagg atttaatccc ttatttaata ttctctctgc taatattctt actacaacat
    42421 tatttatatt cattataaaa ttcctcctac tttctcattt tcatttaata aaatttgatt
    42481 ttctaactct tgtattctct tttcttcatc tgaaataaat gttggtattt cctctaaaat
    42541 tggttctttt gtttctatat ttatacctat aattctattt cttgtatagt ctatacttcc
    42601 atacggaata tcaacaaaat gtaattccgt tatttcatca tgttctaata tatcccctgt
    42661 tgcttctcca gtttggagta atattttccc ggtttggtca catataattc tatttcctct
    42721 ttccatttaa attaccacct ttcatattat tcataagcat accatgtaaa actttctccg
    42781 actttacaac ggtatactac gctactacta tcagtgtatt catctcgata agtatataaa
    42841 gaaaattctt tgctagtaat agtttttaca aacataaaag cacaaaaacg atattctcca
    42901 ctactcttag gaacacgacc aacagaagca agttgattta aattattaat agcataaaaa
    42961 ttaacagtat acccatttcc ataaaaacaa agtttttcaa caatgacaag actagggatg
    43021 aaatttaaat taataggaac agtaagactc ttagcataat tttcagcact tgaatacctt
    43081 gaataaaaat tttcataatc actttgagta aaagtgtaag tacccttagc ccatctttta
    43141 cgttggctta actgattatt taaattagta atctgatttt gaagttgttc agcagtagca
    43201 tctgaactat caaaacctgt ttttattttc tctgataatt caactaatgt attatttaaa
    43261 tttgcttcta tattttttaa tgctaaagtg tttataatac ttgtttttcc agttttaaat
    43321 cctgcattaa cttcaattag tttagaagat atgtcttgca gattcacatc ttcgggcaat
    43381 ggcattatat tcttacttat acttaacact ttttctgctg tagcattatt actgtctgta
    43441 acaactatct taagtgtgtg tagtgcatta tcttctagtg tatagttaat tgttttctct
    43501 gttgttaaat ctgttgttat agtttctttt aacacatcat ctataaaata ttctattttt
    43561 gtaagcaatg tagggtctgt gtggtcagct ttaaatgtag ctgtaatgga attataagaa
    43621 gatactgtta aaaatggtaa tgcttgtagt aatgttattt tagcataacc ataagcacca
    43681 gcagtatttc caccagattc cataacaaca ttatcaaaat aatattcaga tgttggtgtg
    43741 tagccagtag gcttataact atctttagtt aatacgtagc cacttccacc tccacctgct
    43801 cccgcaccat tcattcctgc accaccaaac cagccacctc caccgccttc gccagttgaa
    43861 tctttagcag aacacccttt tccaaaactt ccgttttctg tgcttacacg accaatacca
    43921 ccttgatatt gagtaccgcc gggacgatgt ctgtcgttag cactataccc agtacctcct
    43981 gctaatcctc ctcctgcacc accagtataa ggataatatg aacctccgcc accacctgcg
    44041 acaattatac gagatagcaa accttgctca ttatcccaag caccaccaac aagtcttata
    44101 tcggtagcac caccaccgta catagaataa taagtaccca taatctgttg atttaaataa
    44161 cctttaccac cgccattaaa accactttta gtgttattac tcgtagatga agaagcaaaa
    44221 ccactttcgc cgacgtaaac atataatgta gtttgttttt ttaatgtaat ttcaccttta
    44281 gaatatccgc ctttagcatc agtataccaa gaagaattgt tgatacctcc agaagaaccc
    44341 cagcattcaa atttatattt gccaggtttc aatataacac tttgtggcga accattgtac
    44401 ccaaagttcc attctgtctg cattttctca ctctccttta acaataagtt atcaactcat
    44461 ttacacttgt tgcaatacta gatatcccac catttacttt ttcttctaaa ttaagaaatc
    44521 tatcttcaat tttcttagac gaataagtgg tcatttcaga tactctgttg tcatctacag
    44581 ttgcatttat aaaatgagtt tctgcatttc catttatcaa atatacgtac attttaatat
    44641 tttcttcatt tctaacaaga atactattat catcaatagc cctagcgttt ggtgtaagtg
    44701 cttcaccaat ttcatcatat aaagctatta gtattctttt agtcaatagt ggatgattta
    44761 tagttacttc atacatatta gtttcattat ttaaagtcca atcagccacc tctataatat
    44821 gtgtatgaga tacatttaca ccacctgcaa taatattatc aattttaata ttctgtttct
    44881 cattttctgt gtcaattcta gtgtttaact ctgttttagc agtttctatg ttgcttgtta
    44941 attctatttt ggttgtatca attttagtat taacagtacc tattttagtt tctaagtctt
    45001 gtatatcttt gagtgttgca aagattattg ttgggtcaat tttaagttct atattattta
    45061 cattagatac aatcagcaca gttttaacct tcatgtctac tactgcccct tgttctatag
    45121 aaggtttata acattcttta tatttagaaa tggcaattag attattttca tcatctaaat
    45181 accctatttc tcttatcata aatccgccta cattacttgg tataagactc tctagtatta
    45241 tacaatttgg tgctgtttca tctgtagttg tattcccaat attaccttcc caaactacat
    45301 tttttagagc tgtttggctt tctgttggag tatattcact acctccacca tcaccaagtt
    45361 gaatttttac aaatccgact ttattgcctg taacacttgc atttgctatc tttgcttttc
    45421 ctacatctgt aattatagtg taataacttt tatctatagc caatatatca cctcctaaaa
    45481 tattgttacc tcttgatatc caactccatt tcctgttagt atatcaattt ctccataagt
    45541 ttctatatct ggcggactcc aagggtatat agttatttct tgacccatta gggttgttat
    45601 tccaaaattc atgtaattat ctttactaac taacactcta gtgtaatcaa gactcatgtt
    45661 gcaaggtttg atgctactta caaaagaatg tacttcctca aaccaatctt gatttctagc
    45721 atcactttca agatgtatgt tataggtaga attatttata gttaattcat aattgccttc
    45781 tccaactata ctatctaacc agttcctaag aaatctctct gaataaggta atttacttat
    45841 atatttacta aaaatcctaa accttctatc ctctaaagtc tcatttgact tgggatttat
    45901 agacattatt ttttcccatc tttttatacc acttatagtt aggtcctcta aaaactggtc
    45961 atttgatagg tcctttaatt tatcatgtag tgtttttatt tctttgtttt ctgcattaaa
    46021 tacttttata tattcttctt tatcctgcaa aacttgtggc aagtaattta ttagattaat
    46081 ctctttatcc aactacctca cctctcacta ctatgctgtt actatctatt gttagattag
    46141 atttaacatc atttgtcatt gtgtttgtaa tatctaacac tccatctata cttaacaaac
    46201 gagtttctat ctgagatata cggactatta aattttcttc atcttcccaa ctcatgttaa
    46261 gttcatttaa atagtcatca attacttctt ctgcaattaa ttttatattc tcccaagtgt
    46321 aaccactctt gtatgttatc tctgctgata tatttatagt tgtacttgta actccttcaa
    46381 cggtgactct atgacctatt ggcgctaaac caaggccttc tccttggttt tgtagagggt
    46441 caatttcttc ttgaactaaa ttaactaaat cactagatgg aactttgaag ttagaattaa
    46501 ttattactaa cttaacagta cctccaccgt tccaaactgg atatacttta actcctccaa
    46561 catcttgtat tttgttaact tcatctttat aattttgcat atttccacca aatgattgtg
    46621 aatttaaact atcataatat cgttgcctta gactgtcctc tgattcttca tcttctccat
    46681 ttatcagtat ttctgtcagt tctgctgttt ctaatttgtc tatatattcg ataggtatta
    46741 gttgccccaa ctcaaaaata ggtcccgcag tctcacattt catcttatat atacattcag
    46801 atattctctc aattgctaca tagttatatt ctcctagatt aaacctagaa tcaagtggaa
    46861 tatctatgtt aaaaactcct tttgcaattg tattagttgc ttcgagtggt gtaattcctc
    46921 tttccttaca tcgtttctcc aagtagtaat aactggcagt atctacgaat gtttggtcta
    46981 gtaattcatc catagcaata taagtttcag ataactctat agcaacagga gcaagagcat
    47041 tatatattat agaaccttct ctcttgtcaa gcgtgctagg tacactatct agcattcttt
    47101 taattatatt ttcaaatgtc ataaattcaa acactaaaca ctcaccaccc tctctgcttt
    47161 gatatttcca tatttggtat ggaccataaa tttacaattg acctttcctt ttatattttc
    47221 aaactcaaaa ttatctacat tttcaatcct atcatcttga attagtgctt ctttgattcg
    47281 tctttcaagt tcggggatta caaaggatat aggctctcca ataaggtcgt tcaactcgac
    47341 tccataattc caactatata ttagatgttg gtatctctct gtgtttaaaa ttaaaaagat
    47401 ggtttgtttt aatgcttcca catcatcaca aataccatct atcttagatt tttctatatt
    47461 taatttaaag gtcttacttg gttcttgcct tacatcaaaa ttaattatcg atacatcttc
    47521 tatatcatag tcaatgttat ctgttggtaa catttcatca catcctatct aaaatcaaat
    47581 attgctgtcc tccttgcatc ctaattaaga ctaatttatc tcctatcttt ttatctgtat
    47641 atcttttaaa tgtatctgtt tgtattagaa aagattcttc aaaagaggct ttttgctcta
    47701 tcttaactac taaaggatta acactttcta tagttccaaa tgcaatctgc attgggttgc
    47761 ttgtttctac tgcatccatt gcagctttct ttattatttg taataaatct tggctcatat
    47821 tatcacctca cttaaaagaa tcttctagct cttgcaaaat catgtttttg tttttgtcta
    47881 ccacttaaac tgcttatttt aactacatca ccagtatttg gtgaatgtat gaacttgtca
    47941 tttcctatac atagtccaac gtgatgtaca tttccttttc cttggttgta tgcaaagaat
    48001 actaaatcgc cagcttttac atcatttatg ttgcataata gttttcctct actatcattt
    48061 gattggtctg ctgaaactct tttgagattt atacctgcac ctcttttgaa tgcccacacc
    48121 ataagaccac tacagtcaaa actctttgga ccattaccac cccatttgta aggcttgcca
    48181 agttgatttt ttgcttcttg aataacttta tttactttac tattattgtt tgttgatgta
    48241 ttagcattgt tgctattttg aacttgataa gttatatctt ttaaattctt ttctgcttcc
    48301 tcgttgcttc taacacctgt acctgcacta ttagaactat atgcatttcc cgttatttgt
    48361 ttataaaact tatttactcc tggtacccaa tgtttattaa gaggactatc ataaagtgga
    48421 gcatatttgt ctctaatact ttctaatgtt tttcttccca tatggatata gtttcttgat
    48481 aaattactta tacctctttt tattccttca tccacagagc caaaagacat tcctttcatt
    48541 ccaaagaaat tatttttatt tttacaaagt gaagaacttc cattaccagt ttcatgtata
    48601 gaaatagcag ccattaaagc tgcattgact ttgtaagcat tagaatattt aacaaatata
    48661 cttcctgtat ttgataactt atttttaaat actttattta atttatttat catatcattg
    48721 tcttctttac ttgtagtact ttgtgcagga ccatttttct tttcatcttt attattagta
    48781 tttccactac tatatgagct tgaagaataa gaagcaaatt catctccatc aacaagagtc
    48841 aaatccataa agtgcgaatt attttcaaat gtgtgcttta ctttctcaac taacatataa
    48901 ttttgtaaat caatatctcc taaatctaaa aaaacaggta ctaaacaacc tgctcttact
    48961 ctaatatctc ctaacacatt ttttaaactt aatgacttag ttttcttatt atatagtttt
    49021 agaagtatat cacatttttg ctttatctct gcttcactca tgtttttatc tactgtatca
    49081 aatagttgta gtattcccca acttctcata tgtgtagaat cttgtgcaat atatacatct
    49141 ctttttcctg actcctcgtt gtctctgaca agtttaatct ttgtgtaagt atcactatct
    49201 attgatgaat tatagtcaaa atcctcaatt acatcattgt tcataaccgt atcaagtttc
    49261 attgatgcaa cattctttaa tgttattctt ccaaactcat catataaaac atacatttcc
    49321 tttttctctc ttagagtatc atctagtgct gttagtatca tgtcaaagag tgttttattt
    49381 tcttctatcc tagatatttt atacttagta tcttctatga cattgtattt taaattaaaa
    49441 tctttagcca acatttttac aagttcactt gcagttttat tactatatac ataagtatct
    49501 ttattcttaa aatatcttag ctggtcgtaa gcaacaattt taatgtgatt ttctttatct
    49561 cttttcttct gaaatatata tccatagaag atacctattc ctttataata cagccttaca
    49621 gaatttcctt cgcaaaactc taatatatca tccataacta ttgtaaattc taacttagaa
    49681 ggtgttcctc ttctttctat ctcccatgtg ataccatcaa ggacaactgg ttcgtagaaa
    49741 tcttcccaat gtgcaataac tagccttaca tccctatcat ttgccagaac taattcatca
    49801 gccaagtttt aacacctgcc ctttgtaaat tgtgtattta ggtacttttt tacccttgtt
    49861 agctttatcc atcattgttt tatttaactc atatactttc ttatataatg aaccattacc
    49921 aagttgcttc tggcagattg accaaaggct atcccctgct tttactgtat atgttttacc
    49981 atttggctta ttggatgaat ctggtctaaa ttcttttggt ttcatgactg gagtgggagt
    50041 cctaccatag tttgtctttt caggagttgc aggaactaat tttttagttg agtaatctct
    50101 atattgcttt aactttattg caactttaac atctgaacca ttgtctgcat cttctactat
    50161 gttatattct tctaatgaca ctttcatatt agtgttaaat agtacttttc cacccatttc
    50221 cctcgataca ataaattgaa atggcttaca atcagttttt agtaattcta gcttacttaa
    50281 aaagaattga acatccctaa aagttccacg ataaaaaggt aatttattat gtgtaaactc
    50341 tgcttcaaaa cttatttcag atagcccttc tttttttaat atgtttactt ctccagtatt
    50401 tatcaaatca actgtcttat ttttatttgt aactttaatc tctaactttg gtggaggtat
    50461 tggtaattgt actccatcta aataaaaatc ataagccacg attacacctc ctctctaaac
    50521 tattccctca gcagatacaa ccatagcatc attcagtttt tctgttagta cattaactat
    50581 accatccaca tctgcatctt tacttatgtt attagtgttg ttcatgtcaa tttttatatt
    50641 tacccctgtg aatcggttta ttgtttcttg ctctgcaatg tctctaagat attttaagtc
    50701 ctcttgactt ttatccatag tctttgccat ttttgcagta ttgcctgctg tgtcctttgc
    50761 tccttttgct gcgtcactca aaggtgaatt taatccagct gaacccaatc catcaccaag
    50821 tccgtatttt ttatcccaaa ggtcatctag acctaaatct ttttttgctt tttcggctat
    50881 cttgctaatg tcaaaagtat ctttaaattt gttttgtaat tgatgtccta cgtcatatcc
    50941 ttttataaat tctgacttta aatttttgta ctctactaat tctggtttcc atgctttagg
    51001 ctcaggcggt ttttgaatgg gtttaaatgt tgtttttgta ccaattacag tatttacttt
    51061 ttgaaattct ttcatttgtg gtaaatcaat tcctggaatt ttattaatct gttgtactaa
    51121 ccaattcaat ccttttacag ctatattaac agcttttata ataccatttg ctagattggt
    51181 agcaaattta tcaaaagctt tgtctaaatt aacacctgcc ttgagtcctg cattagccat
    51241 atcaataaag aaacattgca ctgcatataa tccagttcta aagatatttg ctatttcaac
    51301 cacacagata tttatagcat ttactatccc tacaattacg ttgtaaacaa ctgcacataa
    51361 ccaataccaa gctccaacta taagactgat tgcagaaata cttgtgcctg caaagtgatt
    51421 gtaaactgct actaatataa atacagcaga tattactgca attataccta aaactatcca
    51481 aaaaatggga catgcatata tagcagcatt aaatccccat tgttcagctt tgcctatcgc
    51541 taaagctcta gctgttccta aaattcctct ttgtctaata acttcagatg tccacgacat
    51601 ccaatttgct acagttccag ctatagtaac tgcttgcata ataccaagag ctattatata
    51661 ggtactaata gctgaaacta cacctaaaat tataggtgaa attatactcc aatttcgcga
    51721 aaatacatta gcaacactaa gtgcttgtgt tattatccaa cctagccctt gtacaactaa
    51781 actagttcca acaatcatca cattaaaaaa attctgaaaa gctggactac tcagtaaatt
    51841 aataaatcca ctaaatacat taaacccaac tgctccaagt acatataatg agtctttaac
    51901 atcagttatg aaagttcgaa atcccctgct tgaaactgtg tcctcaattt tcttctgtat
    51961 agctccaaat accataactg cattattttt tacactagta aagatttgac ctagcgtata
    52021 aggcatcttc tcgaactctg cattagtctg ctctgctgct gcaagtaatg agttttttac
    52081 aatatctgct gttaacattc cctctgatgc cattcctctt atttttccta tgtccacgtc
    52141 caaataatct gcaatcgatt ggatgatgtt aggtgctgac tcaaacacag cattcagttc
    52201 ctcacctctt aatacaccag aactcaaccc ttgggttagc tgtaacaatg ccgaattcat
    52261 ttcctcagta cttgctccag caattacgaa ctttttattt agttgctctg caaaacctac
    52321 aatttctttt gtactgctaa acgccttacc tgcgttcatg cctattcgtg aaactatttt
    52381 tgcagtatct aagtaagatg cacgagacct ttcagcagat tggaaaatca tcttatttaa
    52441 tcctccatct gagagttgac catcatttat catactaagt ctcgcgttag tacttgtcat
    52501 ctggtcgctt aaatttccta gacctcctaa cgttcttata cctaagtagg ttgctgctag
    52561 cttctttgca cttccaacta atctatctgt agaacttgca cccttattta tatcctcatt
    52621 aagccttcgc tgttgattat ctgattctct tatttgttgt tctagtctat caaagccagc
    52681 ttctgcacgt gctagttctt ctctagctgt tctaatacta ttagcatcta tagcattgct
    52741 agatgttctt tgtaattgct cgaatgaact taatacaata ttcatagcat tattcatgtg
    52801 tctaaaagca ggtgtcattc cgtcgaaaat tcggatagat gtttgtatag ttgccatttt
    52861 taacctcctt tcttttttaa cataatataa gcacttactt atttttaagt aagtgcttat
    52921 atattataaa tttagcaatt cttttttctt agcatcaaat tcttcttgtg taatagcttc
    52981 catatctaac aaattcttat attttaatat ttcatcagct gtagaactag atatagactt
    53041 ttttttgtct tccattacat tatattttgt aattattgat agtattgata atatttcttg
    53101 agcatcagaa aaagctttct gataaataga agagtttgtt tttactttac tattaattaa
    53161 atttatatat tcaattggat tatttatgtc ctttacagtt atttttattt taaatatttc
    53221 tacaactttt ctacttgttt ttttacctgt aattcctcca actacagccc ctgtacctcc
    53281 gaataagact cctccagtta tagcacgacc taaaccacct ttaactatag tttctccatc
    53341 ttccaaaagt tcaaattcta atatatcatc aaattttatt attttctcta ctaatatttg
    53401 atttctattt ttatatgata tttttaaaag attttgctct tcatcaaaag aaattgaaga
    53461 atttatactt tttgtctcgg tgaacttctc taacaatttt aaatttttct tttcaacttc
    53521 tataaacttt ttcattcctt ctgagtttga catcattttc ataatactag ttacttttaa
    53581 aatattttca gagaaatcta tgtacttgca attacaagct gtacaaaaat tttcaccttc
    53641 tatagatggc ataagtcctt tttcgcttcc gcaaatacaa caaggtttct tattcttttt
    53701 actaaacaat cccatttatt taatccccca gtacaatttt taaatatatt atactatatt
    53761 agtaaaattt ttacaccaga gattatcttc ttctacctct ctttgcatct ttgtcagctt
    53821 ttttagcttc ttctttttct tcttctactt tgatatctat agaagcagca acaaatgctt
    53881 tttcatcaac tggtaaatcc atatattcat gcggtttcca tttaaactta tgaaggcaat
    53941 aatgagctat attagaatca taatcacctt cataaattag ttttttgctt cttctacttt
    54001 atcttcaaaa gttctatcaa aaccatttac ctctcctacc tcacttgaaa ggtctgtata
    54061 ttcgccagga gtcaacattg ttgttaataa ctcctctgca cccattacac cataactatt
    54121 ttgtaattct gcatcatgta aatccggaaa tactatagtt tccacacata atttcaaagt
    54181 gtaagtatta aaatctgttt cactagtgta ttgtcctgta gctttccctt ttttatttaa
    54241 tataggtact cttatagttg aatcttttct taattgtctg tccctatctg aatctattgc
    54301 tttaagttcc cattcgattg cttttccatc ttctcctata aacctttcac ttgccacata
    54361 ctttctattc tctactttta ttgcattttg acttaaaaaa gcgtttaaat ctcccatatt
    54421 cttattctac ctccatcacc aaatattttg tttgtttttc tattgttgca acaccagctt
    54481 catttatttc aaattttatg attattggct ttaatgacga accatcaatt gtatctgttg
    54541 ctaacttatc tgaaatatct ataagatatt ttcctgcctt tttatacatc tcgctgacac
    54601 gttcttccaa aggtctttta ttgctataat caaaagaaat tgaatctttt atctcatatt
    54661 tatccttaat tttaatcatc tcctattctt ataaataaaa aatacacata cataaatcat
    54721 aaatgtgtat tttactccat accatttgct atattaaatt tctcaactaa tttccaattc
    54781 tcaaaagtaa aatccatatc ttcatctaaa tactccccat cagcatcaaa tttagcaatt
    54841 atgcctgagt ccatattgca atcttccagt attatagttt gacgacccac tgaacttgtt
    54901 gggtcttcat tggtaatttg tatatcgaag taaatatcct caccagtttc tttatactca
    54961 tacaacaatt ctctaaatat agaggtatta taataaaatg ttgcatttcc tgaatattta
    55021 cttcctgttg atttatttcc ttttgtagta ctacctaata taggtatctc actcttattc
    55081 ttttccattt tagcttctaa gttaatagct tgcataaaat tatatctttt accttttata
    55141 gttacaaaac actctgcctt agatgcactt attgtatctc ttgcttttat ttgttgtgcc
    55201 attattattc tcctttctta ttgttaacta actgaaacag tcatataaag cttactcata
    55261 gcactaataa cttttacagc atcacttact acaacagtct tcttgtcgct tccaggttct
    55321 acagaaacat catcagcttt gaaatcttct attgctctca tattttgcag ttgttcatga
    55381 tgcttaacta catcattcca aaacgagata cgaccagatt tatcatttgg tacttcaccc
    55441 aagtactttg tattaaataa agtcgctata tcattagcaa tttggtcaag tactctaaca
    55501 ctttggttac ttgaaaaatc gtcattttta tcatctgtaa atgatacaaa agtatttatg
    55561 tcctctaaca catgaacttc atcaccaact ttatgaaata taaatttacc actctttagt
    55621 gcttcttcaa gttgtatttg agtgtaattt acaccaacat caaactcacc atcatacttt
    55681 ttattagtat tagatttatt tatatcgcat cctgctatag ctccagtagc ccaataaatc
    55741 aagctagatt caactaaatc tttatcttta atcttatttt ctacagacac tacaccttca
    55801 taatctgcat cacttttctt atatagtact gtttgaaact ttgctcctac cttatctctc
    55861 attctctttg taaattctac aaataaactt ttaatctctg ttgttgtagc caaacatcct
    55921 aaagcattaa atgaataact ttctatttta tctaagaaag cttgatattc tgctcctgta
    55981 actgcttctc cattagttcc atttgtaaaa gttaatcctg ctgtagcttc taatgttgca
    56041 tccttcttcc aagtgatata gtcattgtct tgtaagtctg taatgacttt agctacttga
    56101 atatctacct tcttattatc taaaagtgtt acaacatcaa acttagcatt atcatctata
    56161 tttgttgtaa ctattatctt taagtcatta cctcttattc cactatactt agctatagct
    56221 atagtacaac tggctttaac gcctttattt aatttataaa aatatcccaa ccttatattt
    56281 ttgaataaat ctctcaagcc tttcagcttc tcatgagtat aatcatatcc aaaatacttc
    56341 actgaatact tctcaaaatc atcacttgtg acttgaaata cttcttcatc tatgccccaa
    56401 tctaactcta aaggcattgc aacaatacct ctatccgata atgaactggt tgccctttta
    56461 gctgagataa aatttatata gctacctggt aatactttat tctgtgttac aaatgttcct
    56521 cctcctaaag ccatctaact cactcctttc ataaaattat ttattatttt ctctacctct
    56581 gagaaagaat ataactcatt ttcttttaaa attgcattta ataagtcttt tctatttaca
    56641 tactttttag aattaactat ctgctcttta gtaaacttat agtcatcttc tttattcaat
    56701 gttttactca aaattatcac ctctcttcaa accaccgaat aactctactg tatccatctt
    56761 atctgtatca ttacttttta tagtaaagta gttataatca acaaagaaat gaagaacatt
    56821 atctacaatt tcaaagttca tgtttgtacc tctgactaaa tctccatcaa tttctatata
    56881 ctctaattcc tccagtagca tctcagctac ctcatttatt tcaaatgatt tatcattact
    56941 tttaggaaaa taatgtacat caaaagaatt tttctttaat tctctgccac ttggatatga
    57001 tactttgctt ggatttaaag gaacaataaa aaaacaaggt tcatttatac cttgctccac
    57061 atcttcgcta taaattgtat attcatttcc aaacgattta tctaatttaa tagatattcc
    57121 atctataata ttattaagca tcaaacactc ctttaagcaa tattaatagc tttttctcta
    57181 taatcttatc aatctgacct tgtaactcca tttctgaaat agttaaaaaa tgttgtcctt
    57241 taacccatcc cttaccattc ttagtcctat gcccaaactc aacatatgaa gcatattctg
    57301 ttggattgat aacctctatg atgtaattat taccactttt atacactgga agtgacctag
    57361 cataagctat tccactccaa ccttctctta gaaatcctgt atcaactggt gttcttctaa
    57421 ttactttacc aagcagtctt gctgctaatt ctcttgctgc atctttgcaa aacttatcta
    57481 aatcaatctt tgtaaatttc tccattcttc tacaagctct tttaaactct ctaaaatcaa
    57541 cactgcccca tctagccatt atgccttgtc cttaagtaat tctaagataa tttcttgatg
    57601 gtttggatat atagctgatt ctccacttct tacatattct ttatcattta taataagttt
    57661 tgaacctgct ttaatgttta tgtttggaga tataaagagt ttaatagtct gtacaagttt
    57721 agctactttt tcatctgtag ttgatgtaat atttttatat gaaagcttac atggttgatt
    57781 ttctaataca atcacttctt tattgttagt tcgttttgtt acagggtctt tgattggctg
    57841 atactcaact atagtacatt tatctctata taacatttct attgcttttc tagtcttatc
    57901 catcattatt tccacctaat ttttctgtat ctatttagtt gtgctttata atctttaagt
    57961 aaagattcct taaattcact agctgaactt ctatatgaaa tagatgtgtc accttctgat
    58021 atagaagaaa tagagcctag tgcaacatct tcgcttccta gactctcatt tttatacatt
    58081 tctatagcca ttcttaaaat agtactattt aattgttctg gtatagtagg tacattacaa
    58141 tagtttttga ctatttcttc tacatcttct agtataaact ctagtattgt atctttagaa
    58201 ctatcactct catttaaccc taagagtctt ttaattttta ttattttata ttccatatct
    58261 atatcttatg tctaaaagct accattctaa tttgtttagg ttcataaaca ggtttccaat
    58321 tagttgcatc tgatagttca gctcttgaag gaccttctgt tttagccata ttttcatttg
    58381 taaacttaac tcctctaggg tgcatgataa aagtctttct atttataata taatcaacac
    58441 cagaaccttt tttcttatct ctgtctattt ctgtagctac aaatcctact ggattaccat
    58501 ttcctaaagc tattgcacct tcaccaaata aatacgaagt aaatactata ttagaaccgc
    58561 ttccttcata aggacaacca tcatcaatta taaccctttt attttgataa aaatatattg
    58621 gaccactatt agaaggttga acagtttcaa ttaaattttg ttttcttagt tcagcttcaa
    58681 cagcactgtg tactgcaact gctgttaaag tttcttttgc atcacctaac ttttgttgtg
    58741 catcaataaa cgctgaacca ctccattttg cagcattacc agaacttgaa gaaatatcta
    58801 gtatatttga tgctaaccta gtttctgcta ctgtttctcc aactgcctta gtagttccaa
    58861 atactccttt aagaatagca attagttctt tttgcatatc tctagcccag aaaccagata
    58921 ctaattcagc aatagcacct gctgggtctt ttcctgctaa agcagcactc aaatctgtag
    58981 cactccacat ttttgctctt ctcataatta ctgcgacatc tgcatttgaa gttattttat
    59041 tattttgcaa atcaacatct tcaattattt gttctgattc acctgttaaa tcctcaaaga
    59101 atggcatatt tacaagtgga cttgcttgag aagctaattt atcaaactca gagttattag
    59161 ttataattcc actttgtaat aatgcacttt tttccattgt tctatttatt acatatggat
    59221 taaacaagct tggaacaatt atatcactta gctttgttcc tccttcattc ccagctaata
    59281 attgtatatt catttttaga cttttatttt tattcatatt tacctccttt atgttattta
    59341 ccagcagcag tcattaattc ttttgctaga gctgggttat cattatatat tttgctttgc
    59401 tctgttaaat taaaactttt ttctaaccaa ggattagaac ctttataatc atctccacct
    59461 ttaggaatat aatttggttt accaccagta aataaatgtg gagagttttc cttataaact
    59521 tttattgtgt cttctaaacc aattactttt ccttcattat caaaattaaa cttttcagtt
    59581 cctccttgtt tataaattat ataatcagca tctacaacac ctaaatcttt taatttgcct
    59641 ttcaattcat attctttttt tgagatttcc atatcctttt ttagcttttc taaatcatta
    59701 ttatgtttat cttttagatt ctctacatct tcttttgtca tacctccttc aaacttttta
    59761 atagtttcat tagctgtatt aagctgtgtt tcaagatttg tataatcttc ttgagtaact
    59821 gtagtctctt ttattttctt ttctatagac ttttgaagag aagctacatc aattttgtta
    59881 tcttctactt ttattccttc taataattct tttaaccaat ccatatttta aatatctcct
    59941 ttcattttta cataataaaa aagcctttta aaagactttt aagtaactta tttactacca
    60001 ataaaaatac ctgttagcga taatacaaaa cagattattc ttcctactaa atatcctgct
    60061 atcatgcctg ctaaattaaa aacaagcttc atacaagtaa aagtattagt atctatcata
    60121 ttagctacat ctaatacatt tgctataatt atacttaaac ctacaataaa gcctaaagct
    60181 atcccaacaa ttataataag aactgatata atatctctaa cacttgattt atttggcttt
    60241 ccaatgtgtc tttttatata tcctcttgtg tcttttttaa acatattttc accccccaaa
    60301 atctactcaa tactttctct taggcattcc cctaactgtt ttacaatctt atctatatca
    60361 actttacaat cacatttatt cattttttct gctagtttat caattttatc atctgctttt
    60421 tctaaagttt ctataaaaaa ctctaattcc tttgtggcat ttttaatatt ttcttgaaag
    60481 tttgttgaat ctaaagtcat ctctgttgat aatttatttt ttcctctata ttctactttt
    60541 tgatatgtca tttcaaatat atctgcttta catggatata tttctccttt tacaccttgt
    60601 ataatgtaat cccctttatt agctctcata gtaccttcta atgtttctaa gtcacaactt
    60661 acatgtccat taatgcattt ttcttttata aaattacaaa ctctatcatt ctcaataaac
    60721 catttcggtt ctacatcata acctagttta aaagcttcta cttcaactgg tttcttcaca
    60781 aatttagcca tattacttat ccccctttaa atttttaatt atatcttcat tgctaactag
    60841 taaagaagat atgataaata tcacacctaa aataaaatta agtagtggaa ataaagccat
    60901 aaaaataaaa ttacactttc ttcttacttt tttattttta agaatcttaa tcaattcctc
    60961 attactatca atcttcattt taaataaata aagccctgta caaaatacaa ttattgataa
    61021 aatatataat ttaatcattt caaatcaccc tctcaataaa tttttacata ataaaagcac
    61081 ctactaattt atcatttagc aagtgcttct atcctttatt attaatcttt cttttaatta
    61141 ttttttttct aatttcttgc gcttctttca cttcttcttc tgttaatgtt ctttccccta
    61201 ccactttagc ttgtggtatt tctgtccatc ttggtgctga aaataatttt tcattatcct
    61261 ttttcatatt acacctcttt cattgttata taatgtttgc catcatattc aaaattatca
    61321 gtagttataa atttactatt ccttttaaat aaaatctctg cttcttgagg attatatttt
    61381 cttatatcct tgccatttgt gcttataata tttaattcaa cttgaccgct tggattgtat
    61441 tcccctctac tggatgtaga tatatattca ttatatacta tttccttacc tatttgatgt
    61501 ttatttaaaa agtctatttt ttctttttca ttaaagaaat acaaggacct attcacattt
    61561 cccttataat taggcatctt atctaatgca ctatctaagt tacttataaa atttttatct
    61621 tcacttgtta atgataaccc tcttctaagt ttctcattaa ttttataaga atcactactt
    61681 acatatttat taattgcaag ttgttcatta tctgataact taatgttttt attaatatat
    61741 ttctcatacc attctttata cttcatacta gatggtacat aatatgtttt tccatcttct
    61801 cctcttgctg ctctatagcc ttcttcatca ctaaaaaaag gagctgttgt tgtcctacaa
    61861 cgacaatgaa atggtggagc tgtaactcca acttgataat ctttcatatc aaatactttt
    61921 ccatctagct ctctacatat atttgaagtt cttaaatcta atgtagcaat aatctcatat
    61981 ttctctacat ctaaatcatt gaaacaatct tttctacttg ctgatgcaaa gaaagctgat
    62041 tcagtcatta ttaaattctt agcttgagat ttagacacat taaatctctt agcaaagtca
    62101 tttactaggt tctttggatt ctcaccccta ataattgatt gtgtcagttt agtatatagc
    62161 tcattgatta aagcaggtct atgtttaccc caaattcttt cactaaagtt taatccatct
    62221 gttgcccatg gtttagagat aactttattt attctgttag tatcaagact cattaaactc
    62281 caaccaacgt ttactccttg ttgaacatta aaagctgtat gataatatcc acttgtataa
    62341 atatctctca ttagtttatc aataccatca agttcatttc catagagaac ttctacttgt
    62401 tgctgtattt gtaactttaa agcttcaagc cttgttatat gaactcttgc actagcattt
    62461 tctaactctt tcatccactt ttgatttata gcattttctt taccatattt aatatattct
    62521 tcgacactcc acttaaactc ttctagttct cttgtattca gcagtttctt agcttctaat
    62581 aaagatattc cttcattttt ggcaaatctg ttataccatg ctaatatatc tttttctata
    62641 ctagacatag ctaatttata ttgtttttct aattcaagat aatattttat acttttgtta
    62701 ttttgagctt cttctaattg ttcaaatctc ttcctccaat aatctttatg tttcatctat
    62761 aacaccatca ttcggtatca aatcatcata ctctctttga gcttcttctt tttccttctt
    62821 aatctgtgct atttcatact ctacatcttc tacaatagga ctatttttac atactgtttt
    62881 atcagaaaca ataccaacgc tttttgcaca tatctctgct aattctaaat cattggcaat
    62941 agcatttctt gtccatgttt gatttactat attacattcc aaattcaaaa ccttgcatat
    63001 cattcttatt agttttccaa aactcaattt aaactcagtc tccataagac ctgctttaag
    63061 ttccaaaagt gagtataaat atttgagtgc tacaccactt gcattaccaa agtcaattgg
    63121 ttgtgggtca acaccttgtc cttgctcaaa tatagccttt cttgtcatca taagtaactt
    63181 ttctctagct tcaactggaa tatcaattgt aagtgtgctt aaaccgcttt tatcatccat
    63241 cccattactt tctacctcaa cagttttata cttcttcata tcttccaaga agctttttaa
    63301 atctgttcct ccataattgg ttaaaataaa tataatctct tgtatatctt ctaaatcatt
    63361 tacaaaacca ctaaaaactt tgtcgtaagt atcaattaac gattttacag tatccaaatc
    63421 acttgtcttt atattattat taaagaatgg aatgaatggt aattctccaa aatcatgttt
    63481 aagtgtattg ctattgtcta atatatctcc atttccatat gttatagaga acatattata
    63541 aacttctagt tcatctatat ctaagtcatc tagttttcta tatgcttggc actctgtatc
    63601 tgtccaatat tcatagatta tatagttgtc accattttca tctatttcat catatactct
    63661 aagtacccct ataagttttt tatttaaatc agaggaccat aaaggtatta cttgtttact
    63721 gtcaaccaca ccataattta acttactgtt tttatctttc catagatgta accatgatac
    63781 tccgctatta cttgcattta tacataagtc tttgcatatt ttgggataga tatcacctaa
    63841 aacttctgta atagctttat ttgttctatt attagataca tcaaaagttg gtggataagt
    63901 aaataagtat gatgcctttt gattaactaa caagctatag aaactacttg atattctatt
    63961 gtcagcattt ctgagtggat tttcagtttc ttcctcttcc ctattagaag ttttaaataa
    64021 tatatcattt ttattcttat agtatctttc agatataatt gatttagata ttacatcaga
    64081 atgataggga acatgttttt taatcagctt cttaactact tctatgttca tctattcacc
    64141 tcacttttat ttaagtattg ataatccctt tcgttttaac attacatctt ccataccata
    64201 tctaacagca tctatagtat gattattttt atctggatac tcatctttaa aattaccttc
    64261 tttatctttt tcaagttcat atcctaaaaa ttctctctta gcatttggac atcttatagg
    64321 gtctattatt atttcttcta cttcctcact taagaatttg attccatgtt ctacactatc
    64381 tggacctttt ctagcaccaa ttatttttaa acctagcttt ttaaactcat ttatacttct
    64441 aggttctgca ctatctgcaa ttactttttt attgcttgtg ttttctttta aaataagctc
    64501 aacagctttt gaatttccta atgctacttt ataaagctca aagaatatat ataacctttt
    64561 tcttgtttta tcatagttca taacaatata agataaaggg tctttagcat atccaaagtc
    64621 aagacctctt cttactctat caaatctatt tatctcttca tttgatattt ctcttaccgt
    64681 tacattagta aatacctctc cacctgtacc agttacaaca cccatataat catgctcata
    64741 cttagtagga tttacttttt taagatgttc agcctccact ataaattgtt ctcctaacca
    64801 ttcttttggt acagataaat aattactatg atgaataaat ttatcttctc tcttttctat
    64861 cacctccata ttagtccaat ttctttgact ttctggtgga ttaaatgagt aaaaaacatt
    64921 atatgtattc ccacctctaa gcaaagattg attaacattc ctaattttat ccataccttc
    64981 aaattcatct acttcttcat accaaacata ttttatataa cctttagaca ctttagtaga
    65041 ttttaatttc ttaggtttat cagctccttt aaataaaatt acttgacctg ttggtttata
    65101 agtcatttga agcttagatt ctggtatttc ccattcattt tgaaccccta atgtgtaaat
    65161 agcccactgt atctgttcat aaacagaacc tctaagtgtg tctttaactc ttctaattac
    65221 aactgcattt gttaatttgc cttgttgagc atctctcatc atacctaaaa caatttctaa
    65281 tgatataaaa gatgattttg tactacctct cccaccttta aaccaataat gagtataaac
    65341 atcttgctta ataagtttat gtacattata gaagcttgga gctataatat tttttaatct
    65401 aatctcattc atctatatca tctactattt gaactatacc agtcccttca acttctacct
    65461 tatcagtgaa caacctatac ctcttaccta ataattcagc agctttgttt ctatctctta
    65521 tacttacgtc tttttttatt atttctggac catattcaga aactacaacc acttcctctt
    65581 ttgcttcatt ccttactatc ttagttaaat actccataac ttcttttgca tctgctatcc
    65641 tatttgactc aagttgacct attctttcat caatgtaact ttttaggtat ggttttgtta
    65701 agttctcagc acctattact ttagcagtct tttcactata tcctgctctt attgctgctt
    65761 ctgttgcatt gccagtttca atgtagtaat cacaaaacct cttttgtttt tcagttaatt
    65821 tagccacatc accacctcac tttgttttaa atataaaaaa ggctaagttt ggggtaaact
    65881 tagccttttt caaggggata tattatacac ttgtttcata ctaccattat atcttatctc
    65941 atagtatatt gatgtgacat gtttctatac taaatcaatc attaatcggt cataaatcgg
    66001 acacaaacaa gactttcata ttagattata ttttttagca aagggaagta ttttatctag
    66061 tgcttttttt ctcttttttc ctacatataa ttcgcttata tttaactcat aacttatttg
    66121 tttatattgt aattttttaa aataccttag ttctattaga tttttctcaa aatcatctaa
    66181 taaatttaac atattattaa tcgattcttt tttaatttgt agatatattt tctcattctc
    66241 caatctttca acatatatta actcattttc tattggtgaa gaaacattat ttcctttagg
    66301 cattccattt aattctattc ctcttaaact actccctctt acttttaact ctatttctct
    66361 aatttcaata tccaaattac tatatgagtt taacaattct tctaattttt catagtctgt
    66421 cacttcattt tcacatcctt gcaaattaac agaattttct ttttaattat tttgttaagt
    66481 tattaatgaa atatagctta ttttttaaat atttttatat tgtataactt cttaattaaa
    66541 cccagtccca gatagtccca gatgtaaaat acatccggga ctgctccaag tctagctatt
    66601 tcaatatatc cagacaataa catttgttca gtcccatact attatatata tattctttat
    66661 ataaagggag caaaatcatc acaaaaaatt gatgattttt tagttaaata tataaaaggt
    66721 caaaaacatc tagggacatc cgggacaacg ttgaaattac tatattacat ctagggacta
    66781 catccgggac tatcccggga ctgctctagt aaatacttta tatttcttac cttgtattct
    66841 tttatctttt acttcatatc caaacttttt gactacttgt cttgaaaact caatgtttga
    66901 tataggttgt aatccattta atatacaata ctcttgatat ttcctatata tttcttttgt
    66961 tgattcattt tctatcttat caacttcttt aaaaaatcct aaaataggat tattgacttc
    67021 ttcatattca agtatttctt ttttaacctt atctggtact gtaaattttc tattcttcaa
    67081 tactcttttt aagccttcta atcctagatt tattaaatat tctatagctt cttgctctct
    67141 taatttgtac tttatataag ggtcaaaatc cttatcattt actgaaaaac tagcattaaa
    67201 aggaataata attaatctat caagtactgc tccagtctta tcttttattc taggtatgtt
    67261 gttagctgaa aataaaaact tactatagtt gttaaaatca aatggattct gaccttttct
    67321 ttcaacattt actctatcgc cacttactag ctttttaaat atagcaggat tagcaataaa
    67381 ttcatctcct atatcatctc ctatatttgc aagttttcca aataattcag cagttttaaa
    67441 tctatcactt aattctttta aatcaagtgc tgatgtattt tcatccccta ataatgtctt
    67501 tatcatatca agataggtag atttaccatt tgctttatct ccagttaata taaaagcttt
    67561 tctaagctca ttacgtctat aaaaacagta tcccactact tcttcaagta acattctaat
    67621 ttcaaaatct ccacatgata atttattcat agttttatca actaactttg aatatgctcc
    67681 tggattatag ttccagttaa ctttatttgt tataataaat tctggtgaaa attctataaa
    67741 agaatcatca actatgttat atataccatt cttaaaagcg attaaattag cttctgacat
    67801 acttgtgttc tcacttatta ataaatttaa ataactaagc acctcactcc tcttagcctt
    67861 atttaaattg cttatattat taatcatttc tgcttctatt cttgcttgac catctacata
    67921 gataccatcc ttatataaat gtaactggtc atttatcttg attacatgat tattattttt
    67981 tatgtattta gcaaactcat caaataaaaa tgaacctttt gaattaaaaa atatcttctt
    68041 ttgaaaggat tcgtctctca aaattacttc aagttcatta tcctgtaatg gagtttttaa
    68101 aacatattta ttaataactc ttattgtttc tcttatttcc tcaacagtaa aatcattact
    68161 ctgtagagtt aaaatataat tatataatgc ttgatttctc ccatctcctt ctccaagact
    68221 taaaaaatca attccgtttt taatcggtgt taaatacatt ggtatttctt gtatttcttt
    68281 actatcgtat aaaatttctc tttcaatatt gttgaacttc aaaattgaat aggaattttt
    68341 acatcctaat tttatatctg aatttaaacc tatagctagt ctacattttg ttctattctt
    68401 ttctaaacta gtatttttaa atagaaaatg cttacctcgt gttgtcttgt aaactctaca
    68461 ttttagcttt aaatcttgca ctattttgta tagaatttca ctactttcaa aatcatcaat
    68521 atcaactaac acagtttctt ctgctaaaac gcctgcaaac tctggtaaat tcttaatctg
    68581 ttcataagtt tttaactttt ttacattttt aaatttctca gctgcctttt tattatttgt
    68641 aattatatat cctttaaata tgtcaaagct caccaatcac cacctcaatt acttaataat
    68701 accccaaact gcttgagtct ttcatttgct aaatctatat accaagtttt atctagcttt
    68761 cttggtactt ttttacctat aacacttcca ttttctataa aacatttatc tggagtatta
    68821 gcaaattttt ctggattttt ttctttattt ttgactttat aaataccacc atcattttta
    68881 ttttttgaag caaatactct aaaacattta tcatttaaaa tcttaccgcc aataaatact
    68941 ttttttgttt ttccctctat agttggacta tataaaccat gtgaatattt actacttatt
    69001 tttactatct tttgaaactc tattaaatca ttacatttat ttatagtttc ttcaataggt
    69061 gtattgttta ccatataatt tttaagtgct ttatttataa ttggtaaatc atagtctaga
    69121 tttcctaaat ctttgatata taatcctttt gcttcaactt ctccatcttc tgttataact
    69181 aaataattgt taacatcctt ttgaaatatt ttagtgtata catcaaaacc taaacccata
    69241 cctgtccttt gttcccactc ataacatata tcatctatta attcgtaatc atctattgta
    69301 tttaacttta caattaatcc atctgtattg ctctgaataa gtttacaata accttctaac
    69361 ttctctatta aatcaagtaa taacagctgt ccactaacac atacattatt agcctgtctt
    69421 gggtcatata aattattgtt tttatctttc attcctccat aagtcttatt aactgccaat
    69481 ttgtaggctg gtcttagagg tgatttttct ttttttaact gtaagttttt gtcataaatt
    69541 tcaacgtatt tttgaggatt ttttatattt cttgagtggt aattatatct aatcataaga
    69601 cttggataga aggaattaac atccacatgt aaaaaataac cttcaccata gtattttgtt
    69661 attgctccat gaacaccacc ccaagcaaat acgtgaggta cattagaaat attaattttt
    69721 agatttttag aatagtcatg atttagtggg ttcttatacc agcttaaaac ttccttatat
    69781 ttctcaattt ttagagtatc tggtatttgt aagtcaaatt catcatcatg ttctttcttt
    69841 gtagcttcta atataattgc tgttagttgt gtttgagttt taccaatata tgatactgga
    69901 agtttaaaag ctttaattaa tcccatatgt gcttcaaatt cggattttct ttcaataaaa
    69961 acatctatag tttgttcgac atcatatcta cagtatttta tagtttcttc tatttcatca
    70021 ttagttaatg gtctatcaat gttaaatgat acattagatt cttttatact atgaccttga
    70081 aaaccttcta attgttttaa tccatgaaaa ctagtcataa catcatagtt attaatttgt
    70141 atgtttctta ataagtttga aaacttccaa ccaggttgac ctttaacaat aatataatca
    70201 tttatttctt ttgcattaaa tccacataat aatcctttaa aaatatattg gtcataatgt
    70261 ctactgttgt aaccaataaa aatatcttct ctatgctcta tataaaatga atttaactta
    70321 tctatatcat ttacaataac ttcttctttt ttatttaaaa catctataaa tacaactaac
    70381 cagtcataag agaatacttc aaaatcataa aaaatcattt agaacacccc tctcgctttt
    70441 gctgcacatt ttctactaca atatatgact ttagagttat ctaacttgta aaatcttttt
    70501 ccacaccaaa cacatcttac aattttacct gggcttataa gttccatttt ttctttttac
    70561 tctcatatta attacctacc tttttaatat tacagctaga tgcatgtata cacctagctg
    70621 taataaaatt tctaagctac ttcaaatata tcttttattg taaaggtatt aaaacctttc
    70681 ttctcaccat attcaatagc aaattcaagt tctccatcta tttcctcagc tatatccatt
    70741 atgagttgtg catattggct gtatgattca aattcaactt caatatcagt ttctaaactt
    70801 cttaaaaatt catttactat atgaatttga aaaccttgct taactacttg attcatgaat
    70861 attaatgaat ctttatactc tccttctagt attttaaacc aacatacaaa cattgggtca
    70921 ccttttttag actcgcttaa ctccatttta tttatttcta cttcataagt gccatgtggc
    70981 acatctttaa atttaccact attttcagat gcttctttta tatcttcttt taatcctttt
    71041 acatctattg ctttatcaaa tttactaaaa tccatatcac ataccatcct tttcttttaa
    71101 atttttaatt aataatcttt cttatataat cactcaaact aatttctctt ttttctagtt
    71161 ttcttgactg gtttaattgc ttcttcttgt tcaattactt cttcctctgt ttgttctttt
    71221 tcagttttct cacttgtttc ttctactata ggagtcatct ctacttcttc attagtttta
    71281 gattttttag gcttacttga tttctttatt tcatttttct ctatactaat atcctcatat
    71341 actttcatta attcattata atcaagtgga atttcattag attttacttt taatctaccc
    71401 cctccaaata tcacttcatt agtcttaaat gataatgttc taacgtctcc atcagctact
    71461 actcttgcaa ctatatcaac catacctgct attttatttg ctgctttttc ttgtaaatta
    71521 ggtttgattg ctgttatctt gtcaccacct tttttggtaa tatctttcga tgtatcctca
    71581 tgtgatatta atattatgtt tttatagtca aggttcataa gtcgttttat agtgcttaaa
    71641 aactccgttc taaccttatc ccatgctcta aaactatcat ctgactcatg agttattccc
    71701 atcttgtcat acatgtaaag gcgacaagct tcgtatgtat cttctaacaa gtcaacaatt
    71761 attgtttcaa aatcattttc ttttttctct aattctctta tagcttcttt aaatacatcc
    71821 catgcaagtt gtctctttgt cattctccct tcaactgtta caatatcttt tatagaaatg
    71881 tatggagcat caacaaactt tatatttcca tctgtattaa gcattaaagg cttttcaaaa
    71941 tcatttgcta atgtagtttt gccactaaat ggtgctccat aaatccataa agttttttta
    72001 ttaattcctt ccacacttct tctttcacta tttggtaata acatataatc aatccccttt
    72061 tcacagtatt cttggtagtc acaccagtta cataatttat tttgattttt ttcaaattcc
    72121 ttgttttcaa gacatctttt tatatctaca agaaaattaa taactttatt tggttcgtac
    72181 tcaaccttca ctatttttat ttcagattta tcaagctcat taagtaatct ttgtctaaat
    72241 tgatgtaagt tttctgtttt cttctgtcta atctgaactt taggtacaaa tacatagtac
    72301 aaatctttta tctcatgatt tggatgttgc ttttcataaa aatacttata tagatgaagt
    72361 tgctcacttt ctaaatatct atctatgttg tttgaatatt taaagtcata aatatcaaat
    72421 actctttctt catcttcata atatatggtt gtttcatttg tatttaagtt tgtatcagtc
    72481 atgtatacat gtggtgctaa caaatctata aaccctataa aatcactagt tgttatttga
    72541 acctcattaa acccttttgg taaaatttct tttacttttg gtattaaata atctaacttc
    72601 atcacttcat taatgtgtaa atcggttata cttggataac taaaataata ttcttttact
    72661 gctgcatcaa tatctttttc aataccagta tgaagtgatg ttcctaatat taaagcattg
    72721 ttagaatctg catttaatat tgttttcacc ttgtcaatat actgtagctt atacttatat
    72781 gggcaattct taaatactcc tatcctacta tgtgagaact gcatttactc accttctttc
    72841 tttatttcta aaatcatctt tttaaatcta tcaaagtctt tagggtatag aataattcct
    72901 attccacctg ccttttcaat ttctttaata ttatactttt gtagttcgct tgcttttcct
    72961 ttttctccct tgacttcaat acctataaat ttaccactac aacaaactaa taaatctggt
    73021 ataccacttt ttgtatatgc tgaacctccc caatatttaa taaaccaaca accttgttct
    73081 tttaaaaact ttttaacttt attttcaaat tgtttttctg cactcatata accacctact
    73141 ttaaagatat ttttatatat gcctttttat ttgatatctt agaacaatct gaataaattt
    73201 ctggatattt ttctttaagt ttcttactat caatagtagt tgtggtactt gcttcaatat
    73261 atatcatttt taaaatatca ttatcaaatg attttatatt atagagttcc attgattttt
    73321 ttaactcttc tttcattttc ttttcttcta tctcaaggct tttcttttgt tcacatatat
    73381 taaatatatt tttaaataaa acatagttat tatctctgaa ttcctctaat cctgcatcat
    73441 ctgcaataat tgtcttccca catgtactac attctaagcc acatatatta ctacaagtct
    73501 cgttatcgcc acattcacta caacaaatat tttcaccttt aaaatcacaa atttcattac
    73561 acttaatcat tttaatttcc tttctcaaac aaattatttg tatagtcaac accactttgt
    73621 aagcttttat atatattttc ttcaacacta ttcctacaaa tcatataata ataaaaacat
    73681 gtgttttctt gacctattct atgaattctc tttttgcttt gcataaataa ctcacaagat
    73741 aaagtaagac taaaatatac aatcttatta cacttttgaa gatttaaacc catagctcct
    73801 gcttgatatt gtacaaatgt aattgagtta ttatgctcct cataattatt taaatctttt
    73861 gtagagccat ttactattga tattggtcta tctcttgata attctattaa tctgtctaac
    73921 tcttcgttaa aattgtaaaa tactattaat ctgtcacctg ttgagtttat taagtctcca
    73981 aaagcttcta atttaaattt attgtattga ctacataatt gtctttcata taacatttta
    74041 gttagtgtag tatctccaac aagttcaaca tcatctgaaa tacttataat tgaatctttt
    74101 ttaaacttcc tatactctct tgtagtacta attttcatta cattatctat ttgttttggt
    74161 aagtcaaata cttcatctga catcataaat actgctccat aatctcttaa cttctttttt
    74221 aatctgtcaa cattcttata acctgttaca accttcattg gaaaaccacc aatatctttg
    74281 tactcaacat caatatattg cttccaatat aaatcttttg atatattcca ccctagtagt
    74341 ttaatttgag aatatagttg ctcatattta ccactacatg gagtaccaga aagtagtatc
    74401 acatttttag ggtttaaact tagtacaaac ttacttcttt tagctttttc attttgaatc
    74461 attgatgatt catctaacat taaagtaaaa tcttttaaat ctaataactc ttttcttcta
    74521 aaagctaatt cataattaat tactactata aatggaactt caacaatctt aaaatactct
    74581 atgccttcac taagtttctt tgtaccattg attatcccca tatctggata atatgtttta
    74641 aagtgatata cccaatcgtt aatttttgat ttctgacaga ttaataaatt tgtattactt
    74701 cctagattta ttaatttctc acttcctaca aatgtcttac caagccccat gtcaaggtag
    74761 tatgcacatt tattattata ttctgttagc tttaaagctt cctcttgatg cttatatagt
    74821 tgcaacttat atcaccttct ttattcctgg tctgataaat cttctgtttt taactttcta
    74881 ctacgtctac ttttatattc ttgctctgct tttatctctg tcattgactc ttcaccaaag
    74941 ctattaaata tagctctaat tgagtcaatt atttcacttg cttcaccttt gatttttata
    75001 ttaacttcaa gcattttaaa tctctccttt ttatgttata attttattaa ctttttttat
    75061 tttgtgtgtt ggttactttg accagcactt ttttattgaa ataatcctac taaacatatt
    75121 gcaaataaac ctaccattat taaaactgct attttatttc ctcctaacct agtctttgaa
    75181 gaatgtaatc accatatcta atatcctctg gtatcaatgc ttgatactca atacatccct
    75241 tatctttgct ataataagct aaatttagtt cctcctcggt tgctactact acaatacaat
    75301 taatattgaa cccaaacctc ttagaactta cactcactac atttcctatt tttaattttt
    75361 ctagattaaa attcactttc aatagctcca tctacatcac cccctctctc tttatcaaca
    75421 taatagttct caatgtatgt atgagttatt agtaccccaa atttctctgt aagaatttta
    75481 gctaaagttt cgcctaatgc atctaaattt ggttcaccaa ctgttgttac tgtgtattca
    75541 ctttttttac ccatttaaat cacccctcta ttttcaaaat attccgtatt taatcattgc
    75601 aatttttact cttcatgtac ttcataaaat aacgtgtcta gcatatataa caaaggacta
    75661 tccttatcta taactaattc ttcttcatct ttaatgtaga attttattaa attttcatct
    75721 atgcaataag ttatataatt atcttcaccg atacacatac ctacttcttt ttctatctta
    75781 ttttggtctg ctatttttat atctgctatt gtatcaagag tatctactat tttataaaat
    75841 atcctttctc tatcattcaa ttcataactt tcctcttcct ctcctatata aacgagatat
    75901 ttgattaatt catcctcttc tatatcacca aaaaacttta gcataaactc aaaagtaaaa
    75961 tcattaaata gtttttcatc tatttctgaa tactcaaaat tcattttttt atagttcaaa
    76021 gctgtactta atgcaatttt ctctaaaata tctctatcca tttctaaaat agaataatca
    76081 ttagctattt cattgttaac accatttata attttcttga aatcatctat catattcaat
    76141 tccttaactg ttaaatctat ctcactttca gttccaacac ttactattct gttattttct
    76201 ttcattttct tattcctcct taaatttaag tttctaaagt tgtacttagc aacttctgaa
    76261 tttaattttc aaaactactt aaagcttttt ctagaattgg cattacattc tcataatatc
    76321 taaaattagg cacttgttta tttgaatgtt tagccttatc ccaaacttta attccgaact
    76381 catctgtttt taaattataa gcatttgcta atcctccaac cttattggct gaaatcccta
    76441 atatcttacc tatctctgta gcagaataag tttttttctc cattttagga agtggtatta
    76501 atgtttctcc agaaagtaat tcagtagttt ttgaatacat aatctgttta tattctttta
    76561 tatctacttt gtcagctaac tctaaatata tttttgcttc tcttgccctt gcatttttta
    76621 atcttgcttg agcattcata tattttattt ctgattcatc cttaatatct ttaggtttgc
    76681 tactattaaa tttattattt tcttttaaac tcttcctcat attaaaatat ccatcaacta
    76741 ttttctcata ttgctcccat gctttatcat cttctagtat tttaagtaac tttgcataac
    76801 ccctttcaga taacaaatat atccctgtca atagaccctt attttttgaa cctctataag
    76861 aattaattgc ttgttgagta aatccgaact tctttatttt ggtgtcgttc aaaccgacac
    76921 ctaacaaatc aattatatct atgtcatttt gaaatctttt tctattctta tttataagct
    76981 catttatatg ctttaactct ttattatgta tttcagctat ttctttaact aacattgctt
    77041 ttttgcattc tccaaaacct ccttcgatat catggaattt cataccatca acttctgtaa
    77101 ttcctatcac ttctatttca tttatatttt ctgcatttac aacttcgttc ataatttctt
    77161 cctccctagt tttttgtatt ttttaaacag ctcttgtttc atataagaaa ctttttaatt
    77221 aataaaaaat tcatctatac ttatattata tgtctgtgat ataattctta aatcttcaac
    77281 actaaaatca cctccagttc catttatatt ttgatttata gcagatgctg actttccaag
    77341 tattttacat aactcagatt gtttaattcc tctttccatt aaaaaaatct taaatttgag
    77401 atatgggtta cgtttacttt tcaagttttt cacccccttc tttgtttcat atttgatacc
    77461 taaattatat attattgcaa gtttcattgt caataacttt ctttattttt tttaaattaa
    77521 atcattgaca atgaaacctc atgttatata atttaagtat atctaaatta taaagaggtg
    77581 taatccatga aaaatacagg tcatattata aagattttaa gaattgaaaa aaaattaacg
    77641 caagatgaac tcgcaaagaa tctaaattct agttttaatt taaaattaaa taaaggtatg
    77701 atttcaaaat gggaatcaaa caaagcagaa cccagatttg aatatataaa atatatatca
    77761 aagtattttg atgtttcaat agactattta ttaggaatga cagagtatag aaatatgtat
    77821 gataactttg ataagaaata tgattctaaa aaattaagtt tagaagttaa agagattgaa
    77881 aaaaacggag aaaagattaa agaaaaaaat aaagtattag aaaataagct tttatctagc
    77941 tttagtgagt taaacgatat tggacaaaat gaagcaataa aaagagtaga tgaacttact
    78001 caaataggta aatatgtaaa taaaaatcac atagatacaa tagcagcaca caatgaacat
    78061 ttacatgaag aaggagaaat tgaaaaaata tatcaagatt tagatgatat ggataattgg
    78121 taaaataggt aggtgaactt atgaatagtt atgaaaagtt actctctgaa gcagatgata
    78181 ataatattat tgttagagaa gtttctttaa tttcaaattc tcatggatta tataaaaata
    78241 atagaatagc tttaaataaa aatacactta ataatatgag tgaaaaagct tgtgtgttag
    78301 cagaagaact agggcatcat tatacttcat atggaaatat attagaccta aataaagttg
    78361 aaaatagcaa acaagaatat aaagctagat tgatggctta caacaagtta attggtctta
    78421 aaggtataat agatagtttt aatgctggct gtaagactat aaccgaaatg gcagaatacc
    78481 ttgatgtaac tgaaaagttt ctaaatgaag ctttagaatg ttataaaagt aaatatggtt
    78541 tttcagctac actagataat tatgtgatat tttttgagcc aagatttagt attatgaatg
    78601 caaatttttt gtaacaattc atagtatatt taagagccgt tcagctcctc ttaaatatac
    78661 aataaggggg aatgtaaaat gttaagagta gcactttata tacgtgttag tacagaagaa
    78721 caagctttaa atggagatag cataagaaca caaatagagg ctttagaaca gtactctaaa
    78781 gagaatgatt ttaacatagt tggtaaatac attgatgaag gttgctctgc aactaattta
    78841 aaaagaccta acttacaacg attattaaga gatgtggaaa aagataaagt agacctagtt
    78901 ttaatgacta aaattgatag actaagtcgt ggcgttaaaa actattataa aataatggag
    78961 acttttgaaa aacataaatg tgattggaaa accattttag aaaactatga ttctagtact
    79021 gctgctggta gattacatat aaacattatg ttatctgtag cagaaaatga agcagctcaa
    79081 acatctgaga gaataaaatt tgtgtttcag gataaattga gacgtaaaga agttataagt
    79141 ggtacaattc ctataggtta caaaatagaa aataagcatc tagttattga taaagaaaaa
    79201 aaatatatag ttaaagctat atttgacgaa tacgagaaat caggttctgt taggacttta
    79261 atagaaacaa ttaataatct tcatggcgaa ttatacagtt ataataaaat aaagaatata
    79321 ctaagaaatg aactttatat aggaatctat aataaacgag gattttatgt tgaagattat
    79381 tgtgaaccta ttatatcaaa aaaacaattt aaacaaatcc aaagaatatt agaaaaaaat
    79441 aaaaaaacta ctcctaataa aaacatacat tatcatattt tttctggtct tttaaaatgt
    79501 aaggagtgtg gttatacatt aaagggtaat tctagtaatg ttggagaaaa actttattta
    79561 tcttatagat gttctacatt ctatctaaat aaaaactgtg tacacaatgt aactcataat
    79621 gaaaaacata tagaaaacta ccttttgact aacttaaaac cacaattaca taaacatatg
    79681 gtgaaattag aagcacaaaa tgaaaaaatc agacaaaata aaaaatctaa caaaaaagat
    79741 gaaaagaaga aaattatgaa aaaattagat aaaatcaaag atttatattt agaggatttg
    79801 attgataaag agacttatag aaaagattat gaaaaattac aatctcaact ggataatata
    79861 actgaagaac aggagagtca aattattgat acatcacata taaaaaaatt cttagatatt
    79921 gatattaatg agatgtatag tgatttaagc agggttgaac gcagacgttt ttggttatct
    79981 ataatagatt atatagaaat agataataac aaaaacatca ctattaattt tatataatta
    80041 tttggactaa catatagtat ccactaggtc cgagtaaaca tagaaattct ccttcttcaa
    80101 tatccaaact aatattattt aaaacccttt tttggtcata acttttaaac acattattta
    80161 tttttaagta actcatatct tatctctcct tatatagtta tttttttatt ttaaatttta
    80221 tatcctactt tttcttctaa aattctttca tctaaattat taatttaaac tttacttact
    80281 ttcagatttt gaaccgtatt ttgattccca agttttaagt actgtacttc tgtttttggc
    80341 agcagagttt aaatcaactt cttttataag ctgttcaaat ggttgtttag aataaccttt
    80401 tggaactgga ttatctgtct ttatggaagt aactgctact tcatgtgcat atctatccat
    80461 agctgaatca cttattgccc aatctaaaaa tagctttgct tcttttttta tattatcttt
    80521 tttaactaag gcatttgctt ctaagtccca gcctgaacct tcctttggaa atacaacctc
    80581 tataggttct ccactagata attgttgtgt agctctatat ccaagtgtaa tacctattgg
    80641 atactctcca gagccagcta acttcgcagg ttttgaaccc gagtgtgtat atgtggctat
    80701 atttttatgt aatttatcca tgtaattgta agcatctttt tcacccatca tttgaataag
    80761 ccctgatact gtaagatacc ccgttccaga tgatgctgga tttggcattg ttataagtcc
    80821 tttatattct ggttttatta aatcttcata actttttgga atatctatac ctagtttctt
    80881 aagttcctta taattaacta ctattgctgt ctctgggaca ctcattccta cccaagatac
    80941 atcatcttca gtatctttaa attttttatc aactttatca taatttttag gcttatatgc
    81001 ttcaagtgca ccatcttttt ttagctctat catgttcatt gctgataatc cccatataat
    81061 atctgcttgt ggattatctt tttctgctaa tagttttgaa gctattacac catgagaatc
    81121 cataactatc tctacatcta tattgggata ctcttctcta aaaccttcca tataataagc
    81181 tatctgctct tcctctagtg ctgcatatat tgtaagttta ttatttcctt ttccttgagt
    81241 agtttgtggt gttgttgata tgcaacttgt cataaatgta atcactacaa tgcacagaca
    81301 agtaaatata aattctttca tatcttcccc ctttgtgttt tttccttttt ttatttgttt
    81361 tttattgttt ttgcttatgt ttatataata cacctaattt gttaatataa agttaagtgt
    81421 aaattaacag ttcgttaatt tttagaaatt tttgttaaat atattatttt tagttaaata
    81481 cagtctgttt ttaaacaata tattaatttt tatagtatct acattttaat ttaaacataa
    81541 aaaataagtc taacctctat aaagtagaat gttagactta tttttataag tatttaatta
    81601 tacaaccaaa tcattttttt tcttttcttc aagtgctttt ttaagcacca tatccttaac
    81661 cttcataagt ctagtagtac ttgctctctc attttcttca agcttcatag ctatatactt
    81721 aatagtctca atgtaatttg gtatcattac attttcaaga gcattaacac gtctacgtgt
    81781 cttttctatc tcttgtgcaa gaagctgtgc acttttttca ctttctgcaa gtcttaaaag
    81841 tggttgcata gcatctgaga aagcttccat agcagaatct aattcacctg atgtaaaagc
    81901 aagaccataa ggataaatat cactttgatt gttttcagtt ttaaagtcaa acacaggaac
    81961 atcaacactc attatatttc tcgtagaaac atctactgaa actgattgct ttggcatcat
    82021 aagtgctgaa cccagatact cctgactcat aactgctctt gcgattataa agtttttata
    82081 agcagtatca agagcatttt ctgcttcttc acgcaatcgc ttattttctc ttacaatctc
    82141 aagaaattgt ttcataagtt catcaagttt atctttaaga agcttatgac ctcttgtagc
    82201 agttttaagg agtttcttaa gtctagtcat ttccatacgt gttggattta tatttaatct
    82261 agccacagat atcactcctt aggcatatat ttttcaaaat attcatcacg gatacgttta
    82321 agttcacttt ttggtaacat actaagaagc ttccatccga tttctaatgt ctgctcaata
    82381 gttctatcag ttctaaatcc ttgtgaaaca tattctttct caaattcatc tgcaaactta
    82441 gcatacatta aatcaatctc agaaagtgca gattcaccaa gtatagccat aagttctttt
    82501 gcatccttac ctcttgaata agctgcaaaa agctggttca ttgtatctgc atggtcttca
    82561 cgagtcttac ctttaccaat acctttatct tttagacgag aaagtgatgg taaaacatct
    82621 ataggaggct gtatatcttt tttataaagt tcacggctaa gtataatttg cccttctgta
    82681 atgtatcctg taaggtcagg aattggatgt gtcttatcat cctcaggcat tgtaagtatt
    82741 ggaatcatag ttatagaccc ttcatgccct ttcatttttc ctgctctttc atacatagta
    82801 gcaaggtcag tataaagata tcctggatat ccacgacgtc ctggaacttc ttttttagct
    82861 gctgaaactt cacgcaacgc ctctgcatag tttgtaatat ccgttattat aacaagtaca
    82921 tgcatatctt gctcgaaagc aaggtattct gctgctgtaa gtgccattct aggtgtagat
    82981 acacgctcta cagctgggtc atttgcaagg tttacaaaca ctacagaacg gtcgattgca
    83041 ccagttgctt taaaatcgct tataaaaaat tcagcatctt caaaagttat accaactgca
    83101 gcaaatacaa cggcgaactt agaatcagtt ccacgtactt ttgcctgtct tgcaatctga
    83161 actgcaagat tggcatgtgg caaaccagac cctgagaata taggaagttt ttgccctcta
    83221 accaatgtat taagtccatc tatagcagag actccagttt gtataaactc ggccggataa
    83281 tcacgtgctg ctggatttat tggagctcca tttatatcaa gtcttttatc tggtataatt
    83341 tctggacctc catcaatagg tctacccatt ccactaaaaa cacgacctaa tatatctggt
    83401 gaaactccaa agtcaagact ctttcctaaa aaacgaactt tactttcagc aaggtttata
    83461 cctgttgagc tttcgaaaag ctgaacaagt gcagtatctc catttacctc tagaactttg
    83521 caacggcgaa tttctccatt tgaaagttca atttctccaa gttcatcaaa ttttacacct
    83581 tctacgccgt ttattaacat aagaggaccg gctacctctt gtattgactt atattccttt
    83641 atcatagttc ttcagccccc ctctttttaa taaggtctgc aagctcgtta tctatttcat
    83701 cttcaattga atcgtaagct gcatctatat cgccttcttc tacatactta gcacgaccaa
    83761 tcttttcaag aactgaaagc ttgataatat cgtttatagt aacattttgc ttgatagcat
    83821 cttgtgctga cttatagaat tttaatataa gtcccatcat tctatattgt ttatgaagtg
    83881 atgtataagt atcaacttca tggaaagagt tttgatgaag gaagtcttct cttatagaac
    83941 gagtaacctc tagtatcaat ctatctccat ctgaaagtga atcaacccca accaattgaa
    84001 ctatttcttg aagttcagat tcaacttgta aaagtttcat agcttgagct ctttgagctg
    84061 agaaattatc atttacattt ttatctgccc atacatcaac tttttcctga tagagtgaat
    84121 aactagtcaa ccagttaatt gctgggaaat gacgtttata tgctaaagat gcatcaagac
    84181 cccagaatac ttttactata cgaagagttg cttggctgac aggttctgat gtatcaccac
    84241 caggaggaga aactgcacca attgctgtaa gtgttccttc tctttcatcc atacctagac
    84301 aatttacctt tcctgctctc tcatagaatt gagcaagacg tgaacctaag tatgcaggat
    84361 aaccttcttc accaggcatc tcctctaaac gaccactcat ctctctaaga gcctcagccc
    84421 atcttgatgt agagtctgcc ataagtgcaa cactatatcc catatctcta aaatattcag
    84481 ctattgtaat accagtgtat atagaagctt cacgtgcagc aaccggcata tctgatgtat
    84541 ttgctataag cacagttctt tgcataagtg actcgcctgt tcttgggtct tttaattcag
    84601 gaaattcaag aagaacatct gtcatttcat ttccacgctc gccacagcct atatatacaa
    84661 ctatatctgc atctgcccat ttagcaagct gatgctgtgt aacagttttt ccacttccaa
    84721 aaggtcccgg tatagctgct accccacctt ttgtgattgg gaaaaatgta tctataactc
    84781 tttgacctgt aacaagaagt gaatctggtg ttttcttttc tctatatggt ctttcttttc
    84841 taactggcca tttttgcatc atagttacag gtatatcatt acctttttca tctgtaataa
    84901 cacaaactgt atcttcaaca gtaaattcac cagaatatat ttcttttata gtacccttaa
    84961 ctccataagg aaccataatt ttacattcta ctactgctgt ttcttgaacg ccaccaatta
    85021 tatctcctgc tacaacctta tcaccaacag attttttagg tttaaattcc cacttagttg
    85081 ttctatcaag tgaagatact tcaacacctt tagttatatt agtacctgaa atatcataca
    85141 ttttttcaag tggacgttga ataccatcat aaatagttga aataagacct ggtccaagtt
    85201 caacactcat aggcattcca agagaaacta cttcttcccc tggtcctaga ccggaagttt
    85261 cctcataaac ctgtatagaa gctttatctc catgcatttc tataatctcg cctataagat
    85321 gtttatctga aactcttacg acgtcaaaca tattcgcatc tctcatgccc tccgctacaa
    85381 caagcggtcc tgacaccttt acaattgtgc ctgttttcat attctctcac ctgcaatcat
    85441 atactttatc aaaatttaaa tattccctcc tatattttat tagcacatat atttagcacc
    85501 aataaaattt gagattgtct tttattcaac tttcatctat tctttaaata atatatctgc
    85561 acctatagca cgtttactag attctcttac ttcattcata cctaatccca tacttcctcc
    85621 aatacctgga ataactataa tggcaggaag ttggtaatct ttgtattttg ctattgattc
    85681 ttttgcaagc aatgatgcct gttctgtaat ataaattatc gcatattcat cttcaaccaa
    85741 cttatgtata ctttttttaa tttcgtcact atcataggct gggaagatat ctattccaag
    85801 agctaaaaat cccatgatgc tatctttatc tccaactact cctaccttat acataagcat
    85861 cccttagcct ttcttttata gtatctgcgt ctatattatt aagcttacta gtcaaaataa
    85921 ttctaattgt ttttatctct gattctttag catataaata tgcaattagt ggttctaatg
    85981 taagaggctt aaattttgct cctctaacat attccataag atagtcatca caaagttttt
    86041 caaagacagt aaaaccacta tccatgccat ttttacagac atcagagtaa gaagtagatt
    86101 taaaacatga tgctggagta tctgaggaaa aagcttctaa gaatttttcc ttatcaagtg
    86161 agccacctga aacaaacaca ttcataaaca tatcaaaatc tttcttcata tttttgactc
    86221 ttataaaact ctttagattt gttaaatcac aaactttcat aacataatct attacaaatt
    86281 tgttttggct ttctttagca gtttctttca tactggtaaa ggttgcttta tctagaacaa
    86341 tatcaaccat ctggccattt tgtgtcttat tataaacatc aaatgcctct aatatagctg
    86401 atgacattat cttaggtaaa tcactaaaac tacgatttgc taaagattct ctaagcttaa
    86461 taagaggaat tgtacctcca tcaattaaat atttctcacc atctacacca gaaatttctt
    86521 ctttaatcag cacttttaaa ttgtgatagt catttttata aagaaataca tcaacaaatt
    86581 tttcttcagg agctagactt ttaagaattt catatgtctt tgataattct tgagtcaaaa
    86641 tattctcaaa attatgtata ttattatttg atgtatcagc ataacctgcc tcagctataa
    86701 ttcttaaaga gtcttcaggg cttttggctt ctgccatttg aataaacatt tgtctgttaa
    86761 gaagctgttt ttcaagcact cttattcgtg caacggcata gggataagtt ttttcttctg
    86821 ccatttttta acccctcctt aattaaacaa aatttctgct gcaatttgtt caatatattc
    86881 atgctctact gcaattatgg cttcaaatga ataattgtac tcaatgtcac cttttttaac
    86941 tatgaaacct ccagtaatat ctctagtttc atcagacact ttaatgcctt tttttgatag
    87001 cacatctttt aatgtttttt tatctttttt agataatact atctctgaat catctgtaca
    87061 atttgatttt tcaatcatgt ttagtataat ctcttcatat tcattatctt taagatttaa
    87121 aagtttgttt ttagcttcta aaattacctc ttctaaaatc tcttgttttt ttgataatat
    87181 ttgcttttta gcctccatat aagctcctga tatttcctta gaagccgctt tttctgcttc
    87241 tgcctctgca agctttgtat aggaagccat ttccttttca gctttttcat tagctgaatt
    87301 tacttttaaa tctgcttcac ttttagcttt atccaatatt tcttgtgctt cttgtttggc
    87361 atcagctata attctgtcaa tcattttttg ttcattaccc ataggagtgc ttcctccttt
    87421 tcattttttt tacttatgaa ttataattta taattaacca attgcaattc cattgtaagc
    87481 taagaaagaa acaagtagtc ctaaaagagc atatgtttca actattgctg caaatgttat
    87541 agctttacca agttcttcag gtctttttgc aactattcca actcctgctg ctgctgcttt
    87601 accttgtgct atacctgata ctaaaccaac taaaccaatt ggaagtcctg ccataagaag
    87661 ttgtaaacct tgagctgatg ttggtattgc atctccacca ataattcctg cttttgataa
    87721 aataaggaaa gctatgataa atccatacag accttgtgta ccaggaagaa gttgtaaaac
    87781 tagaagttga ccgaatttac tagggtcttc tgttacaaca cctgctgcgg cttgacctgc
    87841 tattgaagta cctttagcag aacccatacc tgcaaataat gctgctatag cagctcctga
    87901 tattgccaaa aattgaccat ttcctaacgc gtttaaaaat tccatattta catctccttt
    87961 ttattaatgc ttgtatattt tgttttatac ttaaacggaa caaaaggaac tcctccgcct
    88021 tcataaaact tattgaaaaa ttctacatac tgtaacctac ttgtatgaac atatgcacct
    88081 agtgcattta taagaaggtt tattgtgtgt cctacaacac caattacaac tgcaagtatc
    88141 ggaccagcta tagctcctaa aaggttgata acttgtgcta taactcctgt tgttaaacaa
    88201 agcgccataa ttcttgtata agataatata tcagcaaaat aacttgttat accatagaga
    88261 cttgaaaatc ctttaaaaag cttaacagga atacctttaa agcttcttcc ttgagtaagt
    88321 acaagaccta tagcacctat aattgctaaa tattttccta cttctgaaaa tacacctata
    88381 tcccctgcaa caaaaggtat tataagtaga catacacctg ttatacacaa ataccaaaaa
    88441 cctatgtcaa agattgcatc tattaccttt ccacttctta ttaatgtata tgcttttatt
    88501 cccaaaccta catatatatg gataataccg aacagtaacg acattcccat aagtgtcata
    88561 acatcctcta aaggattaat taatgctttt ataggaatta aatcccccaa aatacccccg
    88621 aatataagac cccatacagt agttgaaact ccacagatac caataagttt aattaaattt
    88681 ccttcacctt tttgtatctt taatttatat acaacaaatc cacagactac tgcaattatt
    88741 aacccatatg cggcgtcact tagcatcatt ccaaagaata caacaaagaa gaaagttaaa
    88801 attgtatttg ggtcaatatc ttttgtactt ggatagctgt acatgttagt tacactttca
    88861 aaaggtgtta ctaatttatt gttttcaagc agaattggga agccttcttc tttacttcct
    88921 tcttcagtct gaacacaaca attaaacttt tctgtaattt ctttaattaa ttcatctgcc
    88981 cttttgcttg gtaaccaacc attaagacag aatgttgttt ttgttttgac aagtctctct
    89041 ataatctttt tttggtctct ttctatagtg taaaaatcat ataggttttc aagcatgtgt
    89101 atactatctg catgtctttt aatttcctct gttttgtcct tagaaacgtt ttcctgtcta
    89161 attatcattt cattgtattt cttgatagct tgtaacggtg taccttcttc atttggtaat
    89221 gaaaccactg aaaaattaaa ttcttttaaa acttctaaaa catcatcaaa agtttctttt
    89281 aaagtaatta aataaacata gttcattaac ttgtcagaat tgacaatccc aataacactt
    89341 tctggtattt catcttctaa ttttactctt aaagcatcaa tgtttgcgct tatgggcaca
    89401 gttccaagta tagtttttgt atacttagtt tccatatttt caagaggaat atcaaagttc
    89461 acccatggtt ctaacatact tttattgttg ttaagtaagt ttatgttaga ccttattgta
    89521 cctatctcct tgtgcaaatt gtttaactcc agagcttcag cataaacttg cccttctttt
    89581 tcactatcaa ttttgttaaa ctctcttttt ggtgcaagta gggatttttt ttgtttcact
    89641 agtgaagaaa caatattaat tgcttggttt acatgagaca ttttctgctc tagcattata
    89701 acttcagatt cttcactatc ttttacaaga taatttttta attcctcctc ctcagtaaga
    89761 aaggcactat catcaatctg aacaaaccca cggttcataa gtagctttaa aatctggctt
    89821 ttttgagctt ctaagccaac aatagatatt ttgttcatat taactattgc catattatct
    89881 cactaccttt ccaataaccg cttcaatagc cttacttttt ctttcttcag cagttttttc
    89941 aattttcaga cattcacttt tagcattagc taagatttta tcaacctctg ctctactgtc
    90001 ggtgactgcc ttctcaataa gagtttcttc cataagcttt gcttgttttt ttacatcagc
    90061 aaatatgctt tcacatttgt ttacagcatc agctctgata gactctgcat cagtaacagc
    90121 ttttactttg atactgtctg ctgtctgctc tgcctcaaca atgcttttta ttatttcaaa
    90181 agccatccaa atcacctctc ttaccttttt actatgtata taaccaatta gattttttta
    90241 ttctaattag attactacct cattgttaaa gtataaacag catttttata taataattaa
    90301 tatttttcaa cgtttatttc ttaataaaac atattttaga atagtacttg cctagattta
    90361 catccttttt tgacttactt ttagactatg acatgagtat ggtttttaaa taccattatt
    90421 ttcaataatt ataatttaaa gcgatatagt ttgtcaatag cgttattttg ttttaaaatt
    90481 aacgttatgt cgacatttta aatttttatt ttattttttt tataatttta atttaattta
    90541 ttacatataa aagtttttta tattcttttt caacctctaa ccattgaagt ttattgtttt
    90601 ttttgaattt ttagaaatat ctcgcactat tttatctaac ttttataaat catcaagcta
    90661 tatcgatttt tgtcacctta tttttaatct aattttttta tatctagtta gaaataaatc
    90721 aatattttta aagattgata aaacttacac ctagttctaa tagttttatt ttaaggcaat
    90781 gtattaatct taagtagata atatcattag ttactctata tattcgacaa cattataaaa
    90841 aaatcctcgt accaatcact ccaatcttca ataggatatg ctgctcctcc atttacactt
    90901 ttcagtagat tggatgtata ttcttctccc atagaaaaaa gttcccctac tgtcatatca
    90961 taacctctag atgtaacaac cttacaaaat gaatccataa catcacgttg ttctcttgtt
    91021 tttataagtt cttttctaaa ttcatcatca ttcttagctt cttctaaaat tttagttaat
    91081 ttttcattca ttatgtattt ctccttttaa gtagtctttc tgtaaacttc aataagcttt
    91141 atataaaaag gaagccatcc taaataaact aagatgactt cgcttaactg ttagcaacac
    91201 atttactagt ataaaataat tggtgtacct ggttctatat tttcatatat tttctttgcc
    91261 ttagaaaaag gtgtatttac acatccatgt gaacctgaag acttatatat acttccacca
    91321 aaagaatttc tccaagtagc atcatgaatg cctatgttcc cattaaacgg aagccaataa
    91381 cttacaggtg aactgtaacc ttgaccagtt aatgaaacat ttctagcctt ataattaaga
    91441 ggatatatac ctgatggtgt agcaaatcct ctagctaaat cacctgttac aacgtctgtt
    91501 gatacaagca tttctccatt tttaaagaac cacatatgtt ggccagaaag actaatctct
    91561 acatatgtat ttccaatatc atctttatta cgagatacag ctttttgtat gtaaataggt
    91621 tctcttgtaa catttttacc agcttttaca acatcaacta atgcttcagc ttctttcttt
    91681 ttatctatca accaaccata aattccacct gaaattgtaa tatctttacc tgtggcagtt
    91741 ttaaatggtc ttgagtcacc aaaagtactg tattttttac ttaaacctct tgtatattct
    91801 accatagcat cattatcaaa agttatgtca taattctttt ctgagtctac ttttaaccat
    91861 ttattaattt cagaaccatc taaagtttcc ttacggtcac taaaatcata tgtaacgact
    91921 acaccaacat acttatctaa tgtcttaata gcttgtttca acttttctga atcctttgtg
    91981 ttgtttggtg cttcataaac tttactttca tccagagaaa tagaagtatt cccagaatta
    92041 attgagtttt gtactaactt ataaaaatca tcttttttca ctttgtttcc aagtacctct
    92101 ggtactataa cataagcgtt tttagtgcta tcatacttag gataagcact cttaggttct
    92161 acaacatttt tactatcaaa acaagataaa gcattaaacc ttttttctag taaatcttta
    92221 ttatatgaaa gagttatcat attattatac tctttagact taaatattcc accaatccat
    92281 ccaatagcgc tctgactatc ttttatcttt tgaactttat catctggtgt aaattttaaa
    92341 tcaatatctt ttgcttttat ttgttctttc ttattgtttc tttcctctaa gtttaaagta
    92401 taggaattag tactagatgt taacaaatca tttacttgct caactgtttt tcctgaagcc
    92461 tttacgccat taatagtcgt tccaaagtaa aaatgatttc taaaaaagat tgccattcct
    92521 atataagcta caaacaaaac acctactact atagctatct taaattttag atttttttgt
    92581 ccactttctt gttttacctc ttttccatca atcataatta aatccttcct tacattgtaa
    92641 ttacctatgt accttattgg tttttaaaca aaaccatgta tgccttattt tatataccca
    92701 aattactgta tcattattta tatttttaaa tatatagtta tttctataaa accattttat
    92761 cttttagata aaatgattat tataaatccc ccctttcaaa atcccttaaa cacaatctct
    92821 gctatattaa tatattacca tacttttaat aatcgtggga ctatctatct atttttgtaa
    92881 cactaaacta ctattttaaa aaagaaacta attttgtgtt agtttcttta tcttaactta
    92941 tttttatatt gaattttagc ttaacataac gttgttatat agattctatt taattatttt
    93001 agtttctata tcttttccat ctgcatattc tttaagtaat tccttagcat atccaaaata
    93061 ttcttcaata tcagattctt gactaaaaga aaatatacaa attaatattt catttgcatc
    93121 ttctgttatc attgctcttt cagaatcact agttggactc ccaaatttac ccactgaatc
    93181 agataatata ggaagatttt ctatatttat taattctttc ccaataccct tatactgttc
    93241 tccttcatct cctacagtaa aacatactgg tgaatgtaat ttgcttacat tatatgtacc
    93301 tactggatat aatgatttta ttgatattaa attgtttatt tctactatat tatttattgt
    93361 ataaagaccc ttcccttgaa taattcttct aaccaatgct tctgaagatg ttctatatct
    93421 acttggattt tttccaagct ctttataagc atttcttgca tctttaattt tatctagttt
    93481 cgtaatgtct tcaactttta gactttgatt tatagtatca caaaactcat ttatttcatt
    93541 aattaatttt tctgagcttt tatttactgc tacttttgct tgaatgcaac ccagcttagc
    93601 attaggccat ctttccttaa gtttgtcatc aatacttata tctatcatac ttaaacaact
    93661 cctatacact aaatttttat taaagttttt atcatctata cattatagta ctattctttt
    93721 gttaataaca tgtttattag caaaataaat ttatttttaa tataattttt ataaaataca
    93781 attatttttt gctttatatt agacaataca ttgataaaat aaaaaaacac taattattta
    93841 gcaatgattt attaaaatca agcattcata atagtgcttt atataaaaat caaattttgt
    93901 tttaaagtaa atctaaaaaa ttcttagctg gcattggtcg tgcaaaataa aatccttgaa
    93961 ctaaatcaca tccaaattgt ttcattaact cagcttgttc tttactctca acaccttcta
    94021 taattacaac taaatctagt gattttgcta gagacactat tgattttgct atattgcgac
    94081 ttctctcatc atgttcaatg ccaccaagaa aagacttatc tagcttcaat atatcaattg
    94141 gcatatctct taaacaacta atagaagaat atcctgtacc aaagtcatcc atagaaatag
    94201 aaaatccata cgtcctcaac tcatttaaaa cattctttaa aatatttaac tcattaatag
    94261 ccacagtttc tgttatctct atttcaatga aatctgaact taaattatac atttttattg
    94321 ttttattgat aaattttaca atatctggtt gatacaactc gaccctagat aaatttactg
    94381 aaactggaac tatcttttta ccttgctttt tccattcata taaatcattg caaacccttt
    94441 caaatacaaa tctcccaatt tttaaaatca acttactttt ctctgctatt ggaataaata
    94501 ctgcgggact tataaaacca tgttctggat gattccatct tattagtgct tcactcccta
    94561 tcatttctcc agttacaagt gaaaacttag gttgataata cacttcaaat tgatttttta
    94621 ccaatgctat ttttatatca tctaaaatca ttgattcctc actaagctta ttcctaacat
    94681 cttcattata aatagcataa tttatatttt tacctttagc aacagaccta gccatatttg
    94741 ctttatttac agccttttga atatctactt caccttcttc aacaaaataa atacccacac
    94801 acagagaaat ttcaaagact atactcaaat tactttcaat attacttcgt atattatcaa
    94861 gttttcttat aattttattt cttccatttt tataatcaca gaaaattgca aaataatcac
    94921 ttgaaagtcg tgcatatacc tcaccttctg ttaattcttc ttttaaagct tttgctattg
    94981 taattaataa attgtcacca aattcatatc caaaagtatc attaatcatc ttaaagttat
    95041 taatatcaaa atatactata atataattta aagatggttt atctaaaaga tacttactac
    95101 attctctata aaatttattt tgatttccta tatatgtaac tttatcttca taagccaaac
    95161 ttaatatttc tttttcatta gattttttta tataaattat ataaaaaata attgcaataa
    95221 atattaatac aatagataac actgcatata cagctctgtt gattatttgt tttgaattac
    95281 taaatacaac agtttctgga attgaaaaaa ttaaattcca gtcttttata taattatttt
    95341 cactattccc attatccata gtggcatatc ctaaatatct tctttcttcc aacatattta
    95401 atacagttgc acctgtttta ttttcttgca attctttttt taatctattt acttcttgaa
    95461 tatcattatc ctgttttaac aatttataaa tattttttga taggctatcc ccttgtggat
    95521 gaaggataat tgtaccatta ttttttacaa cataagatat actattattt tcataaaaag
    95581 atatattaat aagtttcatc agagtattga tattgtaagt acaatataaa actccaacta
    95641 ctttatcatt atttaataat ggtactgaaa tagcaatctt ctttatagac ttatttactt
    95701 catcaacata tggacttgaa acatacttct tacctttaat tgagtttttg aaaaattctc
    95761 tatctttcac tgaaaactta tcacctttgg tattttcagc attaccattt atatcaacta
    95821 ttgccatagt gtaaaatttt tgattttcca tttcatctaa aagatttttc attttttcct
    95881 cattaggtat atctggattt gaagcataat agttagaaaa aatatttaaa acatctaaat
    95941 ctttttcaat ttgtctttgt gctagttgag agccttgtac tgcaacttct tttatatgta
    96001 tttttgcctc tgacataaga agatgttttg tatcttctat atagatatac cccattgtca
    96061 aaaataatga tgttaaaaaa agaattgtaa ttaatgtaaa acttttattt ctccctgtca
    96121 ttcgactcct cccctaatta gtcaatactt catatagata atatatcctt tttataccaa
    96181 ttcatcattt atattgtata taactattct taaatgttac acataaaatc aacataataa
    96241 ccataaaaac attcttttat tattataata acactattta attgaatttt aaattaaaga
    96301 ataaaaacta tccattttct caaacaaaaa aactcttata caataaaact ttgttttatg
    96361 tataagagtt tttattttat ctattttata gcaaacttat cttccataat atgaatttaa
    96421 atacatatct tttatttcat tcataagtgg atatcttgga tttgctcctg tacattggtc
    96481 atcaaatgct tgaattacca tttcatctat tgaatccata aacttagatt cttcaacgcc
    96541 aaactctttt atagatttag gaataccaac tttaagtttt aaatcttcaa tagctaccaa
    96601 taaactttgg aatttctctt catcagaatt tccttttaat cctaaaaatg aagctatttc
    96661 agcatatctc tttaatgctt ctggatattt atattgagag aatgctccca ttttctttgg
    96721 tgcatctgaa gaattaaatt tcataacttc tgttatcaaa agagcatttg caacaccatg
    96781 tggtacatgg tggaaagcac ctaatttatg agccatagag tgacaaacac ccaaaaatgc
    96841 atttgcaaaa gccatacctg ccattgtaga agcatttgcc attttttctc tagcttctgg
    96901 gtcttttgca ccattatcat atgcacgtgg aagatattca aatatactct taatagcttg
    96961 taaagctaat ccatttgtat aatcggttgc aagcatagat acatatgctt ctaatgcatg
    97021 agttaaagca tctataccag aagcagatgt taagcttttt ggcatattca tcatcatatc
    97081 agaatcaact atagccatat ttggcatcag ttcataatct gctaatggat attttactcc
    97141 tgtatcttgg tcagttataa cagcaaatgg tgttacttct gaaccagtac ctgctgatgt
    97201 tggtatagct acaaaattag ctttttcacc cattttaggg aatgtatata ccctttttct
    97261 tatatccata aatctcatag ctaggtcttg gaaatctaca tctggatgct catacaatgt
    97321 ccacattatc tttcctgcat ccattgcact tcctccacct atagatatta ttacatctgg
    97381 attaaattct ctcatagctt tagcgcctat cttagcacat tccaaagttg ggtctggttc
    97441 tacttcaaag aatgtagtgt acttaatatt catttcatct aataaatcag taactgcttt
    97501 agtatatcca ttattgtaaa ggaatgtatc tgttacaata aaagctctct tcttattcat
    97561 tacatcttta agttctttta atgctactcc taaacaacct tttttgaaat aaactttttc
    97621 tggtgctcta aaccaaagca tattttctct cctctcagct actgttttaa tattaagtaa
    97681 atgcttaact cctacatttt cagatactga atttccaccc caagacccac atcctaaagt
    97741 aagagaagga gctagtttaa aattatataa gtcccctata ccaccttgag aagaaggagt
    97801 attaattaaa attctacaag ttttcatggc tgaagtaaac ttatcaagtt tttctctttg
    97861 atttacatca tcaatatata atgaagatgt atgcccaaat ccaccatctt ctactaattt
    97921 ttctgctttt ctaactgcat catcaaaatc acttgccttg tacattgcaa gtactggtga
    97981 aagtttctca tgagcaaaag cttcttctat ttcaactgat tctacttcac ctattaaaac
    98041 cttagtatct actgggactt caaagcctgc aagttttgct atagtacaag ctgtttgccc
    98101 aactatttta gaatttaatc ctccatttac taaaattata tttcttattt tttctgtttc
    98161 atctttatct aataaataag caccacgctc tttaaattct tttttgactt cattgtatat
    98221 attttctaat actataaccg attgttcaga agcacatatc ataccattgt caaaagtctt
    98281 agatacaaga attgagttta cagcagtttt tatatctgca ctatcatcaa ttattgctgg
    98341 agtattacct gcaccaactc caatagctgg ttttccagat gaatatgctg atttaaccat
    98401 tccaggacct cctgtagcaa gggtcaaatc cacttctttc ataacagttg tagttaattc
    98461 taaagatggc tcatctatcc atcctattat accttcagga gctccagcta aaacagcagc
    98521 ctcaagaaca acttttgcag cctctatagt agaatttttt gctcttggat gtggagagaa
    98581 aattattcca tttctagttt ttaaagctaa aagtgcttta aagatagcag tagaagttgg
    98641 attagttgta ggtacaactg ctgcaataac acctattggt tcagcaattt tagtcatacc
    98701 aaatgcttcg tctttctcta taacaccaca agttttagtt tctttatatg cattatatat
    98761 atactctgag gcataatgat tctttataac cttatcttca gcaattccca taccagtttc
    98821 tttttgtgcc attatagcta gaggaactct ttgcttatta gctgccaaag atgctgctaa
    98881 aaaaatttta tctacctgct cttgactata tgtagcaaat attttttgag cttctctgat
    98941 ttttgctagt tttttaacta agctttcaac gttatttaca gtatctaaac caactgacat
    99001 aacttcattt tcttttttat tttctattat tacttgttct ttatgagcca ttttaacaac
    99061 ctcctgagat agttttttat ttattatgtt aatttattaa cattatagca tttacttttc
    99121 ctattttcaa gttatttttt taacatttta ttttttatct aatataacat catttctact
    99181 aataatatct agctttacaa atacttaatt taactagata tcactttatt ttttacgcaa
    99241 atcactaatg aaatcatcta aaaacttaag gataacgtta tttttttaac gtttatattt
    99301 ttgtattttt tgcaaataaa actttataaa aagaattttt aatatgatac tctatcaagt
    99361 ttaaaaataa aaatccttga aaatgaaaat taaaacttaa ttaacaagtt aaagtaaata
    99421 tagttaaatg tacaaacatt tacaacatat agtataatta aaaaaatata tattcatgat
    99481 ttttatataa tatgaaataa aatatattta atattatata gataaatttg aagtttataa
    99541 gaaggaggat aagcatggaa aaattaaaaa caattagcgt tttttctttg attataagtg
    99601 taattttaac gattggaggt attggaatag taacttatta tgtagataat ttgtttatta
    99661 gaggactatc agtatttgtt ttaattatgt cctcttcttt tgtatcaaca acagttagat
    99721 tgatatttga agagtcaaaa cgatataaat tctaatttaa aaattggatt aagtaaataa
    99781 ttttaatata gcaaaaatta cggagattag ctcaaaatag actttttagt ccatgaggca
    99841 tttttttgta tgaaattaaa tatattttca tcatttcaac aagaaaaaga ggcttctctc
    99901 tattttgaga cagcctcttt gctagtattg tatctaatac ataatattat aagaaccaat
    99961 tctattgatg tggacttttt ataacaggct gtagctgttt gttctctaga gcaagttcta
   100021 tagttggaat tattagctca gtatgtgcaa tcatagaatt aggctttgct ttgcaattat
   100081 cttgaccaaa aggtacaaaa tatatatttt tagaattaag gagaatgcca atatttttga
   100141 aattaaagct tagagcatca ttcgttgata ttgatattac tagtggttta tcattacgaa
   100201 gatgaccttt tgctgccatt aatactggtg aatctgtaat accatttgct aattttgcag
   100261 cagtatttcc agtacaagga gctattatta taatatcagc aattccttta ggtccaaatg
   100321 gctctgcctc ttcaatcgta actataggtt tatttcctgt aagttcatat gcttttttca
   100381 taaactcttc agaatttcca aatctacaat cgatattttg tgatacatct gaaaatatag
   100441 tgtgtacatt agctccttct ttaaccaaat tctctaactc tataaatatt ttatcataag
   100501 tacaaaacga accagtaaat cctactccaa ttgtaagtcc ttcaagtctc atttctaatc
   100561 ccttctttca tttataatat tttctatagc gttaacaaga atttcaccag atgtctttgg
   100621 tgaatattta ccaggaagcc caaggcaaag agtcgcatta atccctgctt ctttaacaac
   100681 agaataatct actcctccag gagaagaagc tatatctata atagttactt cttgtgatac
   100741 tttttctaac ctttctttcg ttaaaataca ctctggtatg gtgttaaaaa tataatcaaa
   100801 ttgtaaaagt ttttcatcaa gttgacttaa agaaatactg gaatatccaa atgcattagc
   100861 cgtacttctt gcatcattat ttcttgcgcc aacacataca tttgcatcca aagcgtataa
   100921 tttttttgca agtatttgtg cacatcttcc ataacctaat actaaacagt tactttgatg
   100981 tatattgatt atacttcttt taatagcttc tgctatagcc ccttcagctg tagcaactgc
   101041 atttaaaata gcaacatcat tcattttcat aaaatcataa atctgaatag agtgttgctc
   101101 gcaaaattta caaactttag ttggtatgtt acctccaaat aatatttgat taggagataa
   101161 attaattagc aagttatcaa tagtagcatc aagacaatca tccgtatttt caatattaac
   101221 ttgattcttt gtaaatggaa ttggacataa aataatggaa cttttggata gtgcttcagc
   101281 tagtgaagtt gattttccaa cgattccatt tataatttca tttgatatcc cataagtgac
   101341 tacagaatac cctttattaa ttagtttttt taccatgtac acttgtcgca ggtctccccc
   101401 aataacagtt atatcgtatt gatttgacat attgtaagcc tcctttacta tatacaatat
   101461 gtttttatca atacattggt tcactaaaat tactaaatat tatacttata acatttttaa
   101521 taatgctaat ctatctatct tttcagaaga ggtatatgga aatgaattta aaaagataat
   101581 tttctttggg atttcatttt tcattagatt atctttcatt ttaatcaaca aatctttctt
   101641 cgtaattttg tctatagtta ttacaaataa tacaatttga tttcctctta tagtgtctga
   101701 gtacggcaat acaattgcat cttcaatttg aggaattttt ttaacttcat tttcaatctt
   101761 agtagaacta actttaaatc ctccaatatt tataatgtca tcacttcttc cttcaaatat
   101821 taagtatcca tcattatcat aatatccaat atcattgaca gaataaggtt tggttgcatt
   101881 atatactgca tattctgtat tcacaaaaat ttttccttct ctaatatata tatctattcc
   101941 tggaaatggt ctgcctacac ttagaggttt ttcaattagt tcatcatagc ataaatatgt
   102001 aatataattt aattcacttg ccccatagta taaaataatt tcagactttg gcatatattt
   102061 ttttagattt cttgcagtat cttcaaataa taattgagac cctgtaaaaa tacttacaac
   102121 tttgagtact ggttctttta agtgtttaac caaaagttga agttttgtag gtataaggta
   102181 tatgttagtt acattatatt gttttattgt ccttatccat gatttacaat taagacctga
   102241 acttattaca atactacctc cttcatataa tactgacatt atagaattta gattccctgt
   102301 aaaactaagt gttccattaa caaacaagat tgattcccca gagatattaa aaataccatt
   102361 ttgtatagga aaaaatccag cccaactctc atatgttcta tataatacct ttggaacact
   102421 tgtagaacct gaagataaag ctcccataca aatactttta tctaaataat ttataagctt
   102481 cttatattga tacatatata tattaaattt aggattaaaa atagaaaaat taactttttt
   102541 tgctacttca ttattgttat catcatataa atcaataacg tccatagatt catcagatat
   102601 aatgattgaa atattatttt ttaataaaat atcatctaat acttttttag aaagattata
   102661 atgacaaata ataggaatat tttttgaata attaatagca aaaaaactaa tcaactgaaa
   102721 cattatattt ttagaatata ttaaaattgg gatattttca cctaaagaaa tttgctttcc
   102781 tagttcctca ctataactca atatattttc ataagtatat ttttctccat ctataattaa
   102841 aaaattttta tttttatgcc tctctttttt tattcttaaa agttcataat agttcataat
   102901 ctacaccctt tcaagcagta aagctgaacc tagaccacca gctgcagcta tagagcaaat
   102961 tccatatcta cccttagtct tttctaatgc ttttaaaaga tgtaatgcaa taattgcacc
   103021 tgaagcacca tatggatgtc catacgctaa agctccacca aatatattat atctatctat
   103081 taactctgga tactttcttt gaaacaacac atctataact gcaaatgctt cattaaattc
   103141 aacagcagat acatctaaat aattaaggct ttctatctct aaaagtttat ccattgcttg
   103201 tatcgctgat gttggactta aggttgcatc tgttcctatc gtgcatgtgt taataatttt
   103261 tgctttaggc ttctttttta catgttctaa atacttctta gaacatatta taataaatga
   103321 agctccatca ttaataagac atgaatttgc tgcatttgta atagtttctt ttcctaaaat
   103381 tgatggcatc ctatctaata acctttgact catcttatca cgtatacctt catcataggt
   103441 actattattt ataggagata taatatcttc aagtattttt tcctctcttg cttcttttgc
   103501 tcttttatga ctttccttta cccaaaaatc caagtctgct ttctcaattt gatataactc
   103561 tgctactctt tccgcacctt cgagcatact attttggcta ttatcatcag gagaaaattg
   103621 agcaactgta taatttggat tatttgtatt atatcgctta tcattcttat gatatgtgcg
   103681 cattggttgc agagaactac tttcaaaacc acctgcaata attaaatcac actgaccaga
   103741 tttaaccttt gaaaaagcta tgtctatact catcatagca gaagcacact gcatatccac
   103801 agtaaaagca ggtacttcat ttgacactcc tgctgttaaa gtcattaatc tagctatatt
   103861 ccctcctgtc ccaactgcat ttccacatat aatctcatca attttgtcaa tttcatactt
   103921 tttaattaaa tcttttaaaa cacttgctcc tagtaattca ggttgaacaa attgaaaaat
   103981 tccatttttt agacctatat gacttctcaa tcctcctaat ataaaaactt ccttcataca
   104041 ttacaccctt ccttatatta tagatttatc atagatttct tctgagtaca ttgttcagtt
   104101 tagtgcctaa aaaagatgca ataactgact ttattgtatc tccaattaaa aatggtacta
   104161 ctgctgcaaa aagtgctgct tctactgtca tttgattaaa atagcacata aatactgttc
   104221 ccataaaata tataataggc attccaacaa aaattgttat taatatatat ctcttaatat
   104281 cattatttcg tccttttaat aaactaataa ttagtgctgc aaacaaaaac ccaaaataaa
   104341 aaccacctgt tgggcttaat aactttccaa taccagatgt acctccacca aatactggaa
   104401 tcccaattaa acctatcatt atatatacac caactgtact aaatgcttgt cttggtgtta
   104461 aaatcaaagc tattaaattt atcattattg tttgtgctgt tactcctgct ggagtaaatg
   104521 gcaatggtat atatatgtaa gatgatatac acaataatgc tacacatatt gacattttag
   104581 ttaaatcttg aatatttact ttagtatttt tcatttttat aattcccttc atatgtctta
   104641 tttcatttag tttatatgta catatacaaa gcttctatta aagctttgtt ttagtataaa
   104701 ataaagacgt ttttttgtca actattataa ttatttaggt ttacatttaa tttataagta
   104761 aactttatac tgttacttta tattttaata gtcatttata aaactttgct taaaaacagc
   104821 tctatttaga ctatacttgt aaattataat atgatatatt tttatataag attttatttt
   104881 atataaaaaa tagtaacaaa tagtttatac acaagatatt taaaaggaag tgatgatatg
   104941 aaagttaatg aaaataatat agatgaagag ttagatgaac ttagtaggaa agtttactta
   105001 gagtcaccag atttttggat aagtatttct gacaaaataa tagataaagt atttgatgaa
   105061 atgttattat tttttgcagt taaatataac tatttcaata tagtatgctt tgctattgaa
   105121 aacaattatc tggatttaaa catgccttca aaaaacaaaa aatacactaa tataatggag
   105181 catttgttag atacatcaaa acagaatgaa gataaaaaaa tttataatta tcttctaagc
   105241 ttaaataaag gtaataacct agatgaaaga ccaattttag atgaattaaa ctgtaatatt
   105301 agtagtgata cttttgaaaa aaaagatata tatcttccaa agtacttatg tccaagttgt
   105361 aattctaata tatttgatac aggttataaa gtatcaaatg acataacata taaattttct
   105421 tctaaagaag ctgaacctat tgaaatgtgt agtgaagttt cttctatcag atgttgtaat
   105481 tgtgatgaat tattagaaga tattacactt gataaactat ataacctatg caaaattcaa
   105541 aactgtaata attgtggttc taatttaact aaggtaggaa ttattgcaaa gaaaaaaatg
   105601 aactttgatg agaatactga aaaatttaaa gatgtctcaa cattttactg ttgtggaaat
   105661 tgtgactctg aaataagctt atctcaaaga gaacatttta agatttaaat atttataggc
   105721 taaagtaata agattacatt attagatact gtataagttt tttaaatctg taaaaataaa
   105781 tacacttata agaattaaaa ttgctatgaa actagttctt gatgaactaa tttcatggca
   105841 attttctata atctaataat tattaaattt taacaaacct ttattagcat tccataatta
   105901 tttaaaattc tttcaatact ctatagttta taggtgaaag tatctttaat attatatcaa
   105961 acttattatc tttaaatagt aaatttgtta aatctgaaat acaccataca attttatttt
   106021 cctcttttgt agctatatca attctgatta acttacatct ataataaata tctttatctt
   106081 catatagtct attttaaaaa ttactcttaa aaaatcaact agaaaataaa ttaattatcc
   106141 ttttaataga atgtaatcat attatttact atattccatt atgtactctt taaatcctga
   106201 atcttcattt acttgttctt ttactatatt aaaacctttt ttattataaa acacaactgc
   106261 ttttttatta tctttatata ctgctaagct tagactttta tattttttag ttgcataatc
   106321 taaaagttta cctccgatac ctagattttg gtatttgggc tttataaata aagctcctat
   106381 aaagttttta tctattatgc ttataaatcc ttttatttca tctccatcat catatacaaa
   106441 tgtatctgat ataggtatat attcgttttt aacagtatta tagttatttt gccagtattc
   106501 tttacttata aagtcatgtg ctttgattgt acttttttcc catatttcca tgattttatt
   106561 tatgtcttta ctgtttaatt tctttatcat aaattttgtt tcacctcatt tttgtattga
   106621 ttttataatg tttgtaggta agtgtatttt atttagatat gatttagtta atataaggtg
   106681 gatgttttag tatatgctat tgttgattct acaattttat atactgcttt attaatataa
   106741 aataagtttc taaatactcg ttgatattgc taatattcta cttatctacc acttagttga
   106801 tataaaaatt gaaacttcac tatctaataa tttaattaat gatatgctat tacatttatc
   106861 tatttcataa ccaccataaa tcccaggtgt tgaatttata aatataccag cttgctctaa
   106921 atacatcttg taacttttta tttgcctttc acttacttcc aactcttctg ataattcttt
   106981 gcatttcatt ttgcctctgc tttgaattaa tatcatcatt ctaagtgtat tagctaattt
   107041 actaatgagt aacccccccc taataacatt aattgatatt tttattattt atttctacac
   107101 atatgtacat ataacctctt tatattttat ataagtagaa tttttttata attttgacat
   107161 ttaccatatt atattttata tttgtacaaa attttaatag ttaatacaat aaaaaatatt
   107221 actgaaaaaa taaacatcta taattccagt aatattaatt aattttaaac cctttttatt
   107281 atcatttaat aatagtaact aaaaattgac taaatttaac cttatctctt ttaaataatt
   107341 atttcttaca ataaaaaaat aaactatttg aaccaagaac aagcttccca ttaccaaaac
   107401 agctgatgat gctacttcta tatcaaaaga atttttaagt gcagtaagtg caaatattga
   107461 atgtataaca gccactacat aaggaaacaa aaatactatt ccaatctcaa ttgttgaagc
   107521 ttttttaatc tcattatatg tcatacccaa tttatttaac tgttcatact ttttcttatc
   107581 aacttggcaa tccatataaa atttattata taaaaaacta cttgtagtaa caaagaaaat
   107641 taaacctata aatattgcta aaaatataaa tgtagaatac attaatttcc cagttcctat
   107701 cattaattct ttagagaaaa acaaatatgg ttgcatccct gactcattat taaatttatt
   107761 ttcaaattct ctgcatatct ctatagtttt acttgaatcc tctacttcaa atgcagtaaa
   107821 tctatccact ataaattttg attctatact atcataaaaa ttatccttta ccacatacat
   107881 atttttgtaa tatgctggca taacacattc ttccacttgt tttgccacct ttaaacccct
   107941 attccctaca ataatatttt ctttgacgtt attatttcct ggtaaacttg atgataataa
   108001 tgatatacat tcattatctt caaaacttat agacttaacc cctatagttt ctgtaatttc
   108061 taagtactta gattctttca taattctgac attaaaatca cttttcttgg gaaatacagt
   108121 tttaaattca ccattagtcc ttgtatagtc tacattctct ttttttagat tattttctat
   108181 aaacatcatt ctttccttgt ctttttcttt gctatcaggc tttttagggt cattatgcaa
   108241 tgtcattgtt gaataatata ttgtgttagg atatattaaa ttaatttgac gctctacatc
   108301 tttccaaaag gaataaactg tacctatagc agtaaatgct actgcagaag ttatagttat
   108361 caagaaaaat attctagcat tatcctttac cttataaatc aagttcgaaa tccaaagcat
   108421 atttgtattt tttctataaa atctcttgtt tagttttagc ttcttcataa aaaatacact
   108481 aaattgagaa aagaacaagt aagttgctac tatagtaagg gatgtaactg gaactaagcg
   108541 cagatatgtt gtatattggt cggttgaggt aatagcatta taatacgcta ttataaacaa
   108601 acaaatactt aatatagcaa gcattagtga tgttttaggc tctggttttg gagtttttgt
   108661 acctttaagt aacttcaaca cctgattttc tttaactata aaagaagtaa atattgatgt
   108721 taatacagct aaaatcataa aatagattaa agtagacaat atcgcattaa atggtatata
   108781 gaattttaat ggtgataatt ctaaaaaagt agacataatc actaaaaata tctttgcaaa
   108841 gattaagcct attattattc caattacaga agatactata tttattatca tattttctat
   108901 aaagattaat ttcattactt ggcgctttga tatacctgta atataaagta ttccaaattc
   108961 tttatatcta cttttaagaa acacactaac tgaataaaac acaaagaaga ataagaatag
   109021 atatgcaatt atcttactca tcttgagacc ttcttttaaa taatcaggaa attgagatac
   109081 atctaaatct ggatgacttg taaacataat aaaagaaaat agcagtgaag atgatataac
   109141 aatacttgct aagtatccta aatacgcttt aatatttctt gaaatattgt taatagcaaa
   109201 ctgttttata ttcattagtt atcgcctccc aataatgtaa gtacatccat tatctcttga
   109261 taaaactgct ctctactact acccttatat atttcattat atatagaccc atcttttatg
   109321 aataagattc tactacagta gctcgctgct aatgggtcat gagttaccat catagtagta
   109381 actttatttt ctttatttat cttttgaaat agctccatta caacctttga tgactttgaa
   109441 tctaaattac ctgttggttc atctgctaaa agtattgatg gattgttaat caatgctcta
   109501 gcaatagcag tcctctgagc ttgaccacct gatacttcaa aagttctttt tcctaataaa
   109561 tcttttatac ctaatattgt agatacttca ttcaatctct catcttgctc ttttacactg
   109621 accttatcta atgtcaatgg caatactata ttttctccta tagttaatgt atccaataaa
   109681 ttaaaatcct gaaatacaaa acctaactct cttcttctaa gtaatgcaag ttcctcacct
   109741 cttaacaata aaggattctt gccctttaat tccatagttc ctgtagttgg cttgtcaata
   109801 gtagaaatca tatttaaaag agtagttttt ccactaccag atggacccat aattcctaca
   109861 aattctccat cttctatact aaaatttatg tcatttaatg cgttgaaaat tattttttta
   109921 ccatatactt tacttaaatt atttacagtt aaaattttca ttatttaact atccttccta
   109981 atttaatttt tgaaataaca tatatataat tgttaattat aatttatctt agtttaattt
   110041 ttatagatga taaatctatt ttttctatac actaattatg ttagtaaaag ctaatactgc
   110101 aagtactaca cccattatta ttctgtatac agcaaacact ctcattggtt ttttctttaa
   110161 aaaattcacg aatttttcca taactattat tgatacaata aaagctacta taaacccaac
   110221 taccaaagca atccacaatg ttggtgtcat tattgaataa tcaaattcaa ataaatcttt
   110281 tcctgaagaa gccaccatag ctggtactgc taaaaagaaa gaaaactcag ctgctgtagg
   110341 agaattaagt cctgctatcc atccacccat aatagtagat gcactccttg acatacctgg
   110401 ccatgcagac aaaacttgta atgtcccaac ctttaaagct tgtattggag taattttatc
   110461 tatattatct gtggaatgat tcttttttct aaacaaagtt tctactacta ataataaaat
   110521 cccacccact ataaatccta taattacaga ttgtaaatta aacaatgatt ttatattatc
   110581 gtaaaataga actcctataa tcgcaaatgg tatacaacct ataattacat tcattccaaa
   110641 tctaaaacca atctttcctt cttttccacc agtaaatata aatttaaaaa attctataac
   110701 gctatctttt atctttttcc aataaagtac tactactgct aatatagccc caagttgtat
   110761 tacaacctca aacatttcag caaattgccc cttaaaatct attaaattac caaccaaaat
   110821 catatgacct gtagatgaaa ctggaataaa ttctgtaagc ccctctacta tagctattat
   110881 gactgatttc aatataaaaa taacatctaa actcatcaat aaacatcctt ccttttttac
   110941 aaaatttctt tttttatgtt atttctctta tgttatttct tatattaatt gtaatttaga
   111001 ttagaaaatt taactatctg caaacattac acaaacctta catctatgta aggtttgcaa
   111061 ataaacgctc ttaaattttg attatttaac tatgaatatt tcatttaata aattgtataa
   111121 taaaaaagta caattaacta aaaaccctat tgtaacagat aatttacatc tttatcaaac
   111181 tatttacacc tttattaaac tatttacatc tttattaaag tagattgaaa cttctgtacc
   111241 ttttcctact tctgatttta tacttacttt atgacctaaa tcatcgcata ccttttttac
   111301 tagataaaga cccatacctg tagattctcc aaacttacga ccattttctc ctgtaaaaaa
   111361 tgggtcaaat acccttttta aatctttaga aacaattcca attccttcat ctattatact
   111421 taaaattaca tatttattat tttcttcaga ttttatagtt aggtagttac tataatcttt
   111481 agaatatttc actccatttg taattaattg acctattata aatttcatcc attttacatc
   111541 tgtataaaca taagtaaatt tgtctacttg aatcttagga atcattccac tttttataaa
   111601 taaccttttt tcttcattta caatactaga tacaatttca tttaatttgg ctttttcaac
   111661 tataaagtct ttctgaaaat tatctgccct tgcaaaatgc atagccatat ctaacccttt
   111721 atttaatcta tctatttctt ttcttatatt ttcagttact tcttctccct cataatcttg
   111781 aagctgaagg cttataactg atattggtgt tttcatctga tgaatccatt ggttgatgaa
   111841 agttaaatgt tcactatgta tctttttatg ctcttgtatc attgattgat acaatttatg
   111901 ttgttgtttt aaaataactg atatatttct ccccaagaat gagcttccta aatacaaaaa
   111961 tgactcctcc aaagaatgta ctcctttttc aaacagatta tatacttctc tatttttata
   112021 atacttatat attaaaaaac ataacaatat aaaagaacta aataaaagaa tatataaact
   112081 ctctccaaaa ctaataaact tcataagatt acagtaaata attgtcataa ctatgcctat
   112141 ataatatata aaaatataac ctttataatc ttttaaaaat aacttcatac tttctcctta
   112201 ccaattctta tttaatttat atcctaaccc tcggacagtc tgaacagcat tatctatacc
   112261 taattcctca aatcttttcc ttatcctgct aacatttaca tttaaagtat tttcctctac
   112321 aaactcaata tcatcccata tcttttctaa aagataatct ctacttacta cttttgggta
   112381 tctcttgata agacattcaa tcagtatacc ttctttttta gttataatta gattctcacc
   112441 atttaattct agttctaacc tctctggata aaactttaat ccatctagct ccactattct
   112501 ttcgtctatt ttaggtgaat attcaccata tacccttctt atatgactct ttatttttgc
   112561 cattactaca tcatagtaaa aaggttttgt tatataatca tctgctccac tttctaaagc
   112621 tctaatttgg tctacattac catctctagc tgatataaaa attataggta aattcgactg
   112681 ttgtctaata catctacacc agtagaaacc atcaaattta ggtaaattta catctaatag
   112741 aactaagtgt ggcttaaaac tttcaaatgt aatcattata tcatcaaagt tttcttcaac
   112801 aatcacttca aatccatatt tctcaatata atctttaagt aatgtactta ttgatatatc
   112861 atcttccaca atatatactt tataactcat ataattcctc ctaatatacc tatttactca
   112921 tcatattaac agtccaattt taatatatta taatcttttt acaatatata aatttaatca
   112981 tattactaac ttcacaatta ctgacttcat aagtataacc atattattag acatcttaat
   113041 aaaactctat aaaaaagtat ctttttatga ttaattaatc attattatca actaatcatt
   113101 ctaaaataaa ttgaaattac taattcaaaa tagaaaaagt taccttaata aggtaactta
   113161 aacttttact atatttctta cttagtatta ttttatcata gtttctactt agcattatag
   113221 attaattctt ttatgttcac ttttttctct tgtaacttat tttttattaa gaagtcttgt
   113281 gtatcttcaa gcgaagatat gtctttatct gttatatcta aactaaaatc ataccaagca
   113341 tataattctt tagtttcttc aagacttaaa tcaacttctt tagctacttt ttccatagct
   113401 tcatcaaaat tattatttac atattctaaa gtttcctttt caaccttcat aaatctttca
   113461 actatttctg gatgtttctc tgcaaagtct gtgctaacag cagttactat tataccatct
   113521 actaaacctt caccatttgc tacaagttta ctacctgact tcatagcttt aagagctgct
   113581 ggaccagcaa tcaatgcagc atctacgctg ccatcagaaa gagctgctga tgcctctgga
   113641 atacccatat taacaaattc cacatcatcc atacttaatc cttctttatc aagtgctgaa
   113701 atcaatacct gatgtaatat agtccctttt gggcctgcca ccttcttacc tactaaatct
   113761 gctgctgatt ttattgaatt attattagtc aaaatcataa atccttttgg tgacctgcta
   113821 taagtgttta atatctttaa ctctactcca ttagatgcag ctattaaagc tgatgtacca
   113881 cctagtgcat gtaagaagtc tatttctcca gcagctaaag cttgtgtttg ctctggacct
   113941 gtagtaattt cgtggaaatt aacttttata ttatcctttt taaattcctt tccaaataaa
   114001 tcatcctgtt tttgaattat agaaggaaca tttaatggtg attttacata agttaaattt
   114061 atttctgaaa gtttttctcc attatttttt ttagcacatc cagctaaaga tgctgttgca
   114121 agtgttaata ttgttatacc tatcaatagc ttttttaatt tcatttactt tactccttaa
   114181 aatattatta atttctttaa atgcctttat ttgatttcat tgtcattaaa atatcttttt
   114241 ttaatttaat atagtaatct gaagttaaat ctctattata accatcttct atattaaatt
   114301 cttttacttt tctttcgtct gtgaaaacaa ctattttctt gcctatcttt aacgcttcat
   114361 caatatcatg agttacaaat atcacgcctt tattagttga cttatgtatt cttataactt
   114421 cattttgcat atcaatcctt gtaaaataat ctaatgccga aaaaggctcg tccataagca
   114481 acatatctgg attgaaagaa agagctctag ctatgcttac tctctgcgcc atacctcctg
   114541 acaattcatt tggataagag tttttaaatt tctgcaagtt catcatctta agatattttt
   114601 ctacatcaat attacttttc ctattatatt tatttgattt gttcaaatta tcatttgttt
   114661 ctaagcttct aaaattatca tttataattt tactgctaat tcttttattg tgtttaaatt
   114721 ttctaagcac cttgtttaaa atagtatttt ttctttgatt atgaaaagct atattttcac
   114781 ttacgtttaa ccaaggcatt aatctgctct cctgaaaaac aaaaccaaca ttaggtctat
   114841 actctttatt atcattaata aacctaattt caccactatt tataccttca agtgatgcaa
   114901 ttgctctaag caaggtagtc tttccacaac cactttcacc taaaattact gttatatggt
   114961 ttctatctat gtttaaagag atatcactaa gaactacatg ttcttcattg tcaactttat
   115021 aacttttata taaatttcta attatatatc cagagtcaca tactaaatta ttcatatgct
   115081 tccaccatct ttcccttact taccttcttc acaataatcg aaaatatgta atctgtaatt
   115141 attcctaaaa gtccaattac gattatacct acaataacaa catctgttct agacatttct
   115201 tttccatcag atatcaagta tccaagacca gatgaagctg ctacaagttc tgccccaata
   115261 atggctctaa agctatatcc aagagctaac tttaacccaa cagcaatatc aagaatggca
   115321 tttggtatta ttattttaaa tattatctga agctttgaaa actcaaatac tctacccact
   115381 tcaatcagtt ttgagtcaca atttttaatc cctttcaatg tgcttgtaaa gattgggaaa
   115441 aaggatgcta aaactataat tataattttt gattcctctc ctataccaaa ccataatata
   115501 agcattggta ttaaagcaag gggaggtgta ttccttaaaa aatttattag agatttaaag
   115561 tattcgtata ctccactata aattccaaag aatatcccta aaggcacacc tatagcagta
   115621 cttattgcaa aacctatcaa aactcttttc atacttgcat atacattaat aaatattgaa
   115681 ccatcactta tcatatttaa aaatgtacta tatacctttt caggtgatgg taatatataa
   115741 tcactccaaa taccaagata atttgtaatt ttccataata aaagaattat aaaaaatatc
   115801 aaaacactct ttactagcct taaaaactta ttattaaatt tattgaccat ttacaaacca
   115861 tctccattat tacaaccatc tttacaataa aacatttcta ctatgtcata cttatcttca
   115921 aagccatttc ttattttttg tatttcactt aatatttcgt cttcacttga tacttcaaga
   115981 actttttcaa aagtatcttt gaaatatcct aatggaattg gtgattcatc tatttttcca
   116041 agtgatttta caccttcttg ttcagcaaac tctttccatg tataaaacat agcattaccc
   116101 ttatccttaa acttttcact tgcaaagtct cttaattgtg tacatggaca ggttactacc
   116161 aacatatcat ctttactttt tatatattta tcgtataaaa ccctacaagt ccttactaat
   116221 attggttcta tcataggtac ttcaaaatca tttatcaaat tatttctttt taaaagactt
   116281 atactttctg gacatctaca atccaacatt gtattttcag tcttttttgt atactctttg
   116341 tactgctttt ttacatattc taactgtggt tcacattctg ctattatgta cccctttttt
   116401 atcaaatttg ctttaataag gtgaaacttt tctccataca ttctttctgc cactggattt
   116461 attagaagat atttattcat aacgcctcct attatttaat attgaatatt attatcaatt
   116521 aatagtttaa atgagcactt aaattttgtc aatatattaa ttttttctta ataaaacaat
   116581 ttttatctac attttttaat attttaaatg aaatattaaa tagtatatgt aatttatttt
   116641 aattaataat gcatacatct tactaataat ctatttatat aataatctat aaatattata
   116701 taataatact tatataatta gtattattat ttaatagcaa cagttattca cactaataaa
   116761 agtagaaagt ttttaaaata ttatgaaaca tcaaatttaa ttttaaaatt gcatcaaaaa
   116821 atgaagtctc aacagacttc actttttata actcttataa attattcaaa atatttatac
   116881 ttccctttct acttcaaaac gtaaaaccgt cttcaatgat tcaggcgata cttttctagc
   116941 atcacttata taaatttcac gatgtgtgta agattttctt ataagtttat tttttttgca
   117001 aaattcgttc ataatgtcaa agctttctgg ttcattatca tatgaaccta tatgaagcat
   117061 ttgaacacat agcccttcat taatagaccc aaatctaact ttttcaagaa gattatgagg
   117121 ttttttcttc tttactatat cagtagcttt atccaacagg tcttgtgtaa caaaatctgg
   117181 ctgacgtatc attatagtgt aaattaaatc ttctttaata agtacatcta agcctttact
   117241 tttttctccc ttatcccata taccttctaa aggaaaaacc gtatagtcaa aatacccttc
   117301 tggtacaatt ccttttttag gcatggtttt tattgcatat gccaaagaat aaagtactcc
   117361 tattgcttca gtaaattctt tagaatttgg gtctccactc ccttttaaca tgataaattt
   117421 ctgttctggt atttcaacta ttacaggatt ctttttaggt aaatataact ctttatctct
   117481 ttttctccat tcatatttca taaaaatacc tccatatata ttttatacat tgatattatc
   117541 acgctaaaag tgacaacagt gtgtcataat tataaattat attataaaat cttcatcctc
   117601 taattcctca tacactcctt tttggtatcc attaccctta gttgaaaaaa aatcatgtgt
   117661 tttggtttca gtgctaagac catttaatac aattggattt atagcatcta cagtatatag
   117721 cttctcaaac cctagatttt ctaaagctct attcgcattg tattttaaaa agttcacaac
   117781 ctctttttca agcccacttt ctctgtatat aacatttgta tactctatct cattctccat
   117841 aaggctataa agtatagaat acatcttctc ttctaacatc tccttatcca ttttatcaaa
   117901 tgaatcgtat atttcttgtg ctagcaatcc tatatactta ccatgtaaag actcatctct
   117961 aagaataagc gatattattt ctccactagc taccatcttt ccttgaccag atagatacaa
   118021 tggataaaag aatcctgaat aaaacaagaa actctctaaa aatacacttg taaccattga
   118081 taggtataat ccctcttgat ttgtagtatt ttcgtattga gctaaaacta aatcagcctt
   118141 tctttgtaat gttggttctg tttctatcca ttcaaataat tcatctattt ctaaattaga
   118201 aagtagagtc ataaatatag aagaataact ttttgcatgt atttcttcca tagtccccat
   118261 aaaagacaag acagcttttc tttgtaggtt ttctgttaaa ctcatcatag atggtattcc
   118321 attattcccc tgttttgtat ccagtaatgt taaaccaccc aatacttttt tatataattc
   118381 cttttcttta ttacttagtt cattccatac ctttatgtct ttagaaacag atatttcttc
   118441 aggaagccaa aattgtttta cattttgttc ccaaaaagct tgtgtaaatc catcttcttc
   118501 tctattccag ttaactgcat tatgtatttt atgtaaatta aatgtcatat atttctctcc
   118561 ctatactgaa cacactagac actcatgagt atctcttgtc atctttgttc ttgtgtaata
   118621 taaacttttc aaaccttttt tataggcata tatgtaatgt ctagctatat ctctagttgt
   118681 cttttcatct gtaacaaaca gtgttgttga tataccttgg tcaacatggt tttgaactgt
   118741 tgccactaaa tctatgacct ttctcatatc catcctgtat gctgattgat aatacaacat
   118801 attatcattt gttaaaaatg gcattggata tattgtagta gagtctccat atgttcttac
   118861 ttctactggc tcagtaattg gcattatact tgatgtagca ttttgaacat aactaatgct
   118921 ttgagttggt gctactgcca ttaaatatgc attatatatc cctttttctt ttacctcatc
   118981 caataatttt gtccagtctt cttttgttgg tatataaatc ccttcaaata atgctcttac
   119041 cttttctgac ttaggtagat aagattgttc atagtatttt gataaaacct tgctatttct
   119101 tcccttaaca tattctgatt tatcaaatcc ttcaaaagtt tgatttcttt ctatagctat
   119161 tttcatagaa gctttaattg aatagtatct aaccattgca aaaaatacat tagaaaaatc
   119221 tatagcatca tctgaagtat ataaaatatt ttctcttact aagtatccat gtaaattcat
   119281 agctcctaat cctatagaat gagacttgct gttactattg cttaccgttg gcactggttt
   119341 tatatctgtg ctatctgcta caaatgacag tgctcttatt gctgtttcaa ctgtactttc
   119401 tatagtttta ttatccatta cattggctat gtttaaagaa cctaggttac aacttatatc
   119461 ttgtccccat tcattttttc ctccataccc ctctatttct gaaggtgttt gatattgaaa
   119521 tatctcacaa cataagttag acattttaat aattccaaca tcttttaatg tatgttctct
   119581 attagctgta tctatgtaca ctacatatgg atatccactt tcttgttgca tctgtgctat
   119641 ttttgtcaac atctgcctag gatttatttc tttttttctt atatcactat cattaaccag
   119701 tttatcatac cacttatcca tttctatctc atcaagagaa actccatatt tcttatacac
   119761 agtatgagga taaaatgcat atgctacttc atttttttct gccaactcca taaatttatc
   119821 tggtattata gctcctaatg ataatgtagc aagccttatt ttttcatctg catttatctt
   119881 tttagtatcc atcaacaatt caaaatcagg atggaataca gtaaggtaca ccgcaccaga
   119941 accttgtcta gctcccattt gattaaagta actaaatgat tgttctaaca ttttagctac
   120001 tccaacaaca cctccagctg caccttctat atctttgata gattcgccag atgctctaag
   120061 tttagataaa tttagtgcaa ctcctccacc aatctttgat aagtgatttg atgaagatat
   120121 agcatacgat ataccttctg tactatcttc tacagatagt aaaaaacatg ataccatttc
   120181 tccagccctt tttcttccag catttaaaaa agtaggtgta gctggttgaa attcttgttt
   120241 tactatttta tctgccaagt ttaaagctaa atctttatcg ccatttccta gtgtcaaagc
   120301 tacaattaac actttatcat tatatgtttc taatatttcc tttccatcat tgctctttaa
   120361 tgcataattt tgataaaact tatttgcact catatatgat tgaaattcaa acttatgttt
   120421 atcaatcata tcatatatat ttttaataac atctatgcta tactgattta ttacttcttt
   120481 tgaataataa ccttcatcta ttaaatactt caatctttct tctaggttat taaattttct
   120541 caactttggc tgtataaatt cttctatgta actacttaag gcttccttat ccttttccaa
   120601 ttggtacttg ccttgttcat ttttaattat cacttgattg ttaagctcta tccaattcat
   120661 tatttaccgt ccttttaaca taatcttgtg ccataatttc acttaatttg cttattattt
   120721 cttttggtac ttatcagttg aaatcccaaa attaatctat aattatagaa atgcaataag
   120781 tatttttcaa aaacaaaagc actacatata gtcagtgctt tatctattat atactacata
   120841 tagtatatac acaaattttt ttatatctaa acttttatta ctttataatt gacattattt
   120901 ttatttaaag aaatttttat caactcaaat ataaaacaat acaagcttat tatgtcctgt
   120961 ttaaaaattt aaattatctc taaatagctt aaaaatatat tctgatatat tgaaaaaagt
   121021 actttcaaga tgatatttta tatattattt agaagttttt tatttattgt tatataatta
   121081 aatatatgac tattttgcta ctacatatat aaaaataaat ttatgaaggt gattttaatg
   121141 aaaactattt ctaaacaaga attagaaaaa acacttgaga aacattattt atggcttaaa
   121201 aacaataatg ctggagaaaa ggcagattta aaagaattaa gattagaaaa tatggactta
   121261 agaggatact gcttaagtaa tattgacttt tcgtggtctg accttatcaa tttaaattta
   121321 gaaaaagcag atttagaaaa ctctattttt aataattctt atctttcgga ttgttcatta
   121381 aaaaattcta tattaaaaaa tgcagactta agtggtgcaa gttttagatt ttgtgactta
   121441 tctaactcag atattagagg agctaattta gaaaattcca atttagaata tgctacttta
   121501 aatggagtaa tatcagatga aagtactcgt ttttttaaat tgtattgtcc tgaaacagga
   121561 gcatttatag gctataaaaa atgttttaat tttagaatgg tacaattatt aatacccagc
   121621 gacgcaaaaa gagtgtctgc tacatcaaat gcttgtagat gtgataaggc aaaagtactg
   121681 tcaattacta gtgtagatgg taaagaatct tttaaaagtg ctcgtgcata tgctgatgaa
   121741 aattttatat atagagtagg agaaacgatt gtagctgaag attttaatga aaatagatgg
   121801 aaagaatcga ctacagggat tcactttttt ttaactagag aggaagctat tggttatcta
   121861 taaaatgcta aagttttata aatatataaa tacataaaca aaataacaaa agagtataga
   121921 ttgtaatttc aaaaaaatta taatctatac tcttttttct ataacacata agtacatttt
   121981 atttcataaa ttataataaa ttatttatat ctgcactatt gattatttga gaaactttat
   122041 ctatatgttc tatcttacta tccaaactgt cataatactt cttactctca tctctatttc
   122101 taaaagaata aactttttta tccaatttta aagcttcttt tataatatct atattcctct
   122161 tatttgtctc tcctacacta aatcctgtat ctattataat cttggaatca tttaaatttc
   122221 taatagccaa atcgaaactc tcatcactta taggctcaaa tggattttct gtaaacatct
   122281 ttatccccat agttctacca atttcataat caatatcatt ttcatgtatt attccagaat
   122341 acagacctat acctttttta gtaaaagctc tataaattgg tgttgcttta cccccaccac
   122401 caattataaa aacttcattt ttagatttat tactaatttc tactgaacct aaaagactat
   122461 taaagttttt atcatccaat tcataaagcg aatttataat atcctcatct actacatctt
   122521 caggctggcc ataagctatg actttattat tttttataag agcaacttta tcacaacttt
   122581 ttaatgctat gtctatttca tgcaatgaaa gtattactga tattgacttt tctttactta
   122641 attttttcag tatgtttatg agttccaatc tatgttttat atccaagtga gttgtaggct
   122701 catctaatat aattatttct ggttcttgaa caagagccct tgcaaccaac accttttgtt
   122761 tttctccatc acttagttca tcaaaatatc ttttctttaa atgtaaggca tctacagact
   122821 ccaatgcttc atctaccatt attaaatctt tcttagatag actcccaaaa aatcctgtat
   122881 atggatacct tcctatattg actatatctt gtacagtcat taaatcacct aataatctat
   122941 ttgtaagtac taaagccatt ttttttgata atgcttttct tgatatacaa tttatgttta
   123001 caccattcaa atatatttca ccttttattg gtgatataag tttagataag gaccttaata
   123061 gggtagtttt tccagctcca ttacttccca aaagacatag tatttctcca ttttttactt
   123121 ctacatttat attacttata acaactttgt tattgtatcc tacacttaaa ttattagttt
   123181 tcaacatgtc taagccctat ccttcctttt caccaataac attactacaa ttggagctcc
   123241 taataaagat gttattgtac ttattggtaa ttctactggt gataaaatta ctcttgatat
   123301 taaatcacaa agagctgtaa ctatactgcc taaaaatatt actactggta tcaaaactct
   123361 attatctgat gttttaaata tcatttttga aatttgtggc actgcaagtc caataaaccc
   123421 tataggtcct gcaaatgctg atactattgc tgctaatata ctagatataa atactatcaa
   123481 aactctaaaa aatcttatat ttatgccaat actttttgca tactcttctc ctagtaaaaa
   123541 agcatttaaa ggttttatta tgaatacagt catcaaaaga cctaatatac caactattat
   123601 aagtatttct accttttccc atgtaaatcc agaaaaactt cccatagacc acatagtaaa
   123661 ttcttttaat ttatcactat ttgcaaatga ttgtaacaca tttgttatac cactacatac
   123721 atatccggtc ataattccta ttattaaaag agttgttata ttctttacct tatttgcaaa
   123781 taaaatgact atagacatta caattaaagc tcctataaaa gctgctacaa atatactcat
   123841 tgaatttaca ctctcaaatc ccaatgtgta tcctcccaaa atcatgagag ctactgataa
   123901 agtagaacct gaagatactc ctaatatata cggttcaact attgggtttt taaaaaatat
   123961 ctgtaataaa atacctgata ctgctaggca tgctccacct accatggttg caagtactct
   124021 agggattctt atattgtata ttattttata atgttctgta ttatccatac ctcttaatac
   124081 aacatctatt acttctttaa attcaatttt tacagagcca aatgctacac acactaaaaa
   124141 agtaagtatc atacttataa ttaatactat aaatattgtc gtattcctta ttctcatttt
   124201 attgataaaa tccatttgta tactcctttt agcaaagcta tattaactaa aatctataaa
   124261 acctatcttt ttgtgtcctc tctgtactat ttatcataat ttatataatg tttgattttt
   124321 tcacctgtag tacctgggtg gaacatctca actaaatcta ctattaattc gtctgtctta
   124381 tctactgatt gataataatc tggagcaaac acccataggt tcccgttttt tacaacatcc
   124441 aaatcagcca atacaggtgc actagatttt atagaatcta aatttggtgc ataatctgaa
   124501 cttgatgagt atacaaatat atctgcatct tttgcaactt catgcaattg ttcaatactt
   124561 actcgccctt catttgaatc tattgaagca catgcattta ttccaccagc catttttatc
   124621 atattatcca catatgaatc tttaggagct atataagcac ttccttcata tacagatgcc
   124681 catacaactt taggtttagc tttgtttttt atttttttac ttacttcttc taccttttgt
   124741 acagttttat ttagttcact agtagccata tcttctttat cataaaatgc agctattaaa
   124801 cttgtccact ccattcttcc aaatggattt tgctctttat actcattgtc tacaacataa
   124861 ttaagcccta attcttttaa tttgtcaata aattttgtat cagcctctga taaaccacta
   124921 ctcactatag ttaagtcagg atttaagtct actatttttt cataatctgg tgctaaattt
   124981 gaaccaacgt aatgtatttt tccatctttc attaaatctt taatttcttt aatagtccag
   125041 tactgctctt gtgttgttac ggcttttata ctatctagtt catctattgt tcttagagaa
   125101 caagcctgtg ttgtagatgc tattaataca ttgtccacag gcgttctaac tatattagca
   125161 tttttatatt tttcaggaat tttaatcttc tttgggatta aaatcagttc tcgattatct
   125221 ccatcagtta cttttttaat tccatcttct aaatcttcaa cactaaatcc actagcatat
   125281 tttaattcta atttcttacc agtactagct tgtttattct ctttgtcact tttactacac
   125341 cctataagac ctcctaccat aaaaattacc atagcaatta aaaaaaactg ctttaaaaca
   125401 tttgatttaa atttcatctc tttcactcca atatcttatt ttttatgagt ggctaaaaaa
   125461 ctttaataat atatgctttt taaagtatac ttattaaagt tatcctaaag tcatctttaa
   125521 taagtataac cttttaataa aataaaaaac ttctcctaat ttaataagga gaagttcata
   125581 tatcaacttt acaaaaacga attgatactt cattttatta taaattacaa tctccaccct
   125641 aaattgaact tatataatac tgggcaggtc tcctgactca cggcttttcc tccatcaccc
   125701 ttcccaaaat ttttataaat ttcagtggat tttgatttcg tatccgtata cagtagcggg
   125761 ggctgtagtg aattttcatc actttcccta ttaaactaat atagtaccct agtattattt
   125821 taatttaatt tttattaaga taattgtaat ttattgttga cctctttgca aggttgattt
   125881 aacatatatt taattcattc atcaattttt taatttcaca tacttgtttt tcatttggtt
   125941 ttacaaatgg agcagtcata taatcactta tttgtaaccc tctgatattc atagcttttt
   126001 tcattgctgg tataaatgga ttggttatta agtaaaaatc cattgcttta ttaatatatt
   126061 tttgaatttc tataaccttc tccatatctc tattattgta agcttcagcc catttggagc
   126121 aaacttctgg aattaaattt gataaccccc ctatacaacc tgctccccca gacattagat
   126181 tatgtataaa gttttcatca taaccactat aaaccttaaa ttctgggaac tctattttca
   126241 tagtatttat taaatctctg gtatgtccca tcaaagttac tgtatcctta tatccaacta
   126301 tgtttttatg ttttcttgca agtcttaatg taagttctgg acttaaatca taaccagttc
   126361 tatctggata attgtacaaa tatatttcag cctctgtatt cttagctatt tcactataaa
   126421 ataactcaat actatcatca tcaagagaga aataataagg gcttattatc ataacaccat
   126481 ctgctccact attatgtgca tagtttgaaa gttctataga ttcatttata cacatacgac
   126541 ttgtacctat aaacactttt actctcttat ttacatgact agttactaaa tctataagtt
   126601 ctttttgcat atccatagac atattaaaga actctccagt acttcccatt atgactagtc
   126661 catctacacc tccatctata agatggtcat acactttttt attaccttct ttatctaaat
   126721 ttccttcttc atcaaatatt gtaacaactg gtgtcaaaaa ttctgctttc ataatttaaa
   126781 ctcctaaaat ttattttaat atgttcatta atacatcaga tttagcttta atattaatta
   126841 tattaaaaca gttacttaat gtaatttttt aaaattccaa tactctcaat ctcacattca
   126901 actacatctc cactactcat atatcgagga ggtgaaaatc ccatccctac tccagaaggt
   126961 gttccagtag ctataatgtc tccagcctct aaagtcatac cttttgaaag ttctgaaact
   127021 atgtctgaaa cgtctgatat gaataaccct gtattagaac tttgtctttc ttcaccattt
   127081 accctactac atactttaag ttttatggga aaaggaactg cacttttatg taaaatacat
   127141 ggacctaaag aggtaaatgt atctaatcct tttcctctaa accattgaac atgttctttt
   127201 tgcaactttc tagcagaaat atcatttata acagtgtaac caaagatata atcttctacc
   127261 tcttcttttc taatattaac acctgtttta cctattacta ctccaagttc aacttcatag
   127321 tctagttgat tatttatctc aaaatgacca tctatctcat cttctggacc tattgccttt
   127381 gtcacacgtt ttgtaaaata aaccgttttt tgtggttctt caaaactatc atcaaagtga
   127441 gtttgagttt cttcaagatg gtctttatag ttcactccca cacataagat atcatgtatt
   127501 ggtttttcta taggaacatg tacagtacat ctctctcttt taaaaacatc ataattatag
   127561 aatgtacttt catttataat agttttcaac ttaataatat cttcactaga tacattttga
   127621 attaattcat ttaaatcctt aaaatttcta ctgagattta aagagttaac atctataata
   127681 aataattcat ctttagaaaa aactccagtt cttttacatt cattttctcc ttcagtaaaa
   127741 cttacaaact tcataatctc accctttatt aaaattctat gtatttattt tcttacttaa
   127801 agattataca tagttgcata ctctagctat tgccatttca gtatatccaa gggactctgc
   127861 ttttgattgt tttccatttg ctacatctac aaccatattt aacaaatcat ctgttaattc
   127921 ttccattgtt tgtggaccat atataactgg actagcatca aaatccagat tatcttccat
   127981 atttgcaaaa gttattttat ttccagttat ttttattact ggtgctattg gatttcctga
   128041 tggtgttcct cttcctgtac taaataccac tatttgtgct cctcctgcta ccataccagc
   128101 aacagatgaa gcatcatttc caggggtatc cattataaca agacctttct tatcaatttg
   128161 tttggcataa tcatatactt cacttatttg tctatgacca cctttatgta tacaaccaag
   128221 tgatttttct tctaaacttg ttaaaccacc agctatattt ccaggagatg gattaccttc
   128281 tctaacttct tctccaacca attttaatga attttcatat ctatgtacta tatgtaatat
   128341 tttttctttt acttcttcat ttactgctct cctagctagt atatgctctg cacctataaa
   128401 ttcagtagtt tcacttaaaa ttgatgttgc tcctaaatcg acaagtttat cacttaattc
   128461 acctattaat ggatttgctg ctaatccact tgttgggtca gacccaccac attcagttcc
   128521 tagtataagt tcagatattg gaaattcttc ttttctaagc aaagaagctt cttgtgccat
   128581 ttctctagca taacgaacag ctttttctat agtttttaaa gttccatgtt cttcttgtat
   128641 tacaagagtt tttattggct tatttgttct ctcttttatt gcatcaacta ccaaatcatt
   128701 ttggcaattt tcgcatccca aagatacaac tattacacca tatacatttg gatttgctgc
   128761 ataaccagcc ataacatcca tagttaattg ttggtctgaa tgtacttgtg aacatccatt
   128821 ctgattatta aaggtaactg ccccttgaac ttgtgatgct attattctag ttgtatctga
   128881 tgcacacaca ctcgtaggca atattaatat gtggtttctt ataccaactc ttccatctgg
   128941 tcttttatat ccataaaatt tcatactgat ttcctcctaa aatagtctat atactttcta
   129001 taatttttat atattataat ttttattaca ctcactaatc aaacagctaa aaacctattt
   129061 aaaaactatt tgacactaaa atcaatgaat acaactttta taactctata aatattattt
   129121 tatatattag tcataacttg tttatccaaa tcctctctaa cacttctaac attatgaata
   129181 tgtacatgtt gaccactttt tatctcctga tttgcttctc ctatatgttc accatattta
   129241 gtaactttat caccttgggc catatctttt atagccaatt tatgataaat agttatatca
   129301 tctagtgctg taatcgtttt tactgttttg tcttttaatt taaaactaat ttcactacct
   129361 ttagctattg cttcaatagc tactgcaaca ttatcttttt catcaattat cactgcattt
   129421 atcattattc ttgctctcct ttataaataa tataatttta ttaatatcct aaaatctaat
   129481 taaagaattt attattttac caacaactca ctgtaatata aattaagctg ttattgtacc
   129541 atcctcattt tgttttggga acttaggaca tccatacttc ttagcccacc aactagttat
   129601 aagaggtact aatattgcag tgacaactac tgcggctgcc acttgtgttg tagctgttgc
   129661 aacatatggt tgccatgatg ggtcaactaa tgcaacagca gcaggtacag caattgcatt
   129721 tccagcagtt gtagctacag cccatcctgc atatcctgga cgttttccta taaatttatc
   129781 acagaatact ataaatatac ctcctacaaa tacagatatt aatccaagta atactcctga
   129841 taaacctcct tttagtatac ttgcaagatt tatgctacta ccaagtgcaa accctacaaa
   129901 aggtacgagt aaattacacc ctggctctaa aaactctttc atttttttgt caaaatttcc
   129961 tattatcata ccaacaagta ttggcactat tgcagccaat aatgacaaca atggtacatt
   130021 tgcaagacct gaagtcccaa gagctattaa tgtaaaaaat ggtccatcat ttaaagtaag
   130081 taaactcata gttgcacaat ctgtttcatc tccatatgaa gtcatcaatg aaagatatat
   130141 actaccatta ctatttgtaa ctgcacttat aacagccaat gttgtaagac caaggacacc
   130201 atccattcca aatagctttc ctataagtat acctatcaaa gcacctatag caaatttaga
   130261 accaagaagt ataccacctc tctttaaaac ttttggcatt tctctaaatt gaagctgagt
   130321 tcccaagcat accagttgaa ccccaattat agttgcagac ccaacacttg aaaatactgc
   130381 tgtcgtaaac gaacctattt gtacaatatc tgggcaaaag gtattaatga aagctgctat
   130441 aaacattggc actatcatca tacctgcagg aattttttta ataaaatcca ttatcataaa
   130501 gttaatcctc ctaaaacatg atatttaatt actcttatta agtttttagc tttaattcta
   130561 acggccgttt cggttcgtat ttaagaacta agtttttaat tacgaatctt tgaattaatg
   130621 atagcatttt cctatttatg agtcaataaa aaaaataaat ttttgtcaaa attttttcaa
   130681 actttctgat aataccttgt atattatcaa atgacttcct tatatgcaaa aatacagcgt
   130741 atttaaaatt atatagtatt caaaactata aagtttttat acagtgtaaa aaatagataa
   130801 aatataagtt cataatattt tgatatttac atataaaaat aactattgca tatatttact
   130861 taaattatat aactaaatat cacttacttt ctttaggtac attttggaaa ttagttattc
   130921 cttaatgtac agtctaaaaa aatatctatc tgtatctaaa tcaagagctt atttatatat
   130981 aaatttacat atttattttc tacattgtaa aatatcgtat agtgtgctaa aatcaacata
   131041 ttctaatact ttaaattaat aaaaagaggg ggaaatttat gacttcagat aatcatcgcc
   131101 caacagctag gatattagat attttagaag cattagcaga atccgaaaat ggatatactc
   131161 ttacagaaat agcagatgtt atcaatgctc caaaaagtag catctttcct atagttcata
   131221 cacttaatgc tagaaaatac attactattg ataaaaacac atccaaatat tctataggga
   131281 tacgttctta cacattaggg tcttcatttt ttgaaaaaag aactattttt aactatataa
   131341 ttgacgaaat gactaatata gttaattcct gttctgaaac ttgtcagctt ggtatacttg
   131401 acaataatga agttctttat attggaaaag tagattctcc agaaccaatt agacttattt
   131461 cttatgttgg aaaaaaaata cctgctaatt gtacaggtct tggaaaagct cttttatgtg
   131521 attttgacaa ggaaaaacta ataagcttat atccagatgg tctaaaaggt tttacagaaa
   131581 aatcaattac agattttgat gttttatacg accagcttct tgaagttcaa agaacacaaa
   131641 tagcttcaga gtgtgaggaa tcaatggaac acctaaaatg tcttgccgta ccaataagaa
   131701 aaaatggatg tataagagct gctgttagtg taacactgcc tttatttaga gctaatgacg
   131761 aaaaaataga actgataaaa aaattactct taaatgctca gaaaaatatt caatcaatga
   131821 tggaagaacg taatgaagac attgtaataa attagattaa tattctgtat atggaagata
   131881 tcaaaacata ataattaaaa attttgtttt aaactaatgt atttatttga tttatactat
   131941 aaaaacaaag ttgctgattt aactacagta actttgtttt ttttataata ttttttatat
   132001 ttttattgac atgataaaaa tactatgtta aattctaatc ataatcgtaa ttacgaatta
   132061 agttcttata taagaaccaa caatcctatc tcaatctaag atacgatata ttatgagtaa
   132121 gttagtgaaa attgttagat atatattttt acataaaaat caatgaaaat aaaaggagat
   132181 tttagttatg agcatttatt atgtaccacc aataaattta cttgggaaag gatgtcttaa
   132241 tgaagctaaa gattcaatta aatcattagg aactaaaaaa gcatttattg ttagtgataa
   132301 atttctagtt tcaaatggta ctgtaaaaaa agtaacagat attttatctc agatagatgt
   132361 agactttgtt gtttatgatg aagttaaaca aaatccaact gtaactaatg tgaataaagg
   132421 acttaaaata ttaaaatcag aaaattgcga cttcgttata actataggag gtggttctcc
   132481 acaagactgt ggtaaagcta tctctatatt agccactaat ggaggagata ttagagacta
   132541 tgaaggtatc aacaaaactt ctaaaaaatg tcttcctatc atagctataa ctactactgc
   132601 tggtacatct gctgaagtta caataaacta tgttataact gatgaagaca gacatgtaaa
   132661 gatgataatg gttgatacca attcactagc cacaatgaca gtaaatgacc cagaattaat
   132721 gattagcaaa ccatctaatt taacagcagc aactggtatg gatgcactaa ctcatgctat
   132781 agaagctgta gtagctaatg gtgcttatga tgttacagat tcaactgcct tatatgctat
   132841 aaagcagata tttaaatacc ttccaagagc tgttaaaaat ggtaatgaca tagaagctag
   132901 agaacaaatg tgttatgctt gttttttaaa tggaattgcc tttagtaatg caggtcttgg
   132961 aaatgtacat gctatggctc atcaattagg aggtttatat gatttacctc atggagtatg
   133021 taatgccatg ctacttccaa tagttgagga ggaaaatgct aaatcagccc ctgccaaatt
   133081 ccgaccaata gctgaagtta ttggaatgga tgtaaataat aaatcagata aagagtgtgt
   133141 tgactttgta atagataaga taaaagctct ttctgaagag gttggaatcc caaaatcttt
   133201 aaaagatgta ggtgttgata atcctaattt tgaattgctt gcagaaaact ctatgaaaga
   133261 tgcttgtgct ggtgctaatc ctgttttctt tgataaagat aagattatag aattgtttat
   133321 gaaaatatct taattatgta tatttataag agagtgcctc aaaatatctt tgttttgtta
   133381 atagcactct cttattacac tttttaaata gtactcttta tgagaagtta atatataatt
   133441 ctattaattt aagaattatt atcccaataa aaaactcaaa atttttctta atgaattata
   133501 actgttgttg tatctggtat attatcatat atccactttg cattttccgt acttaatctt
   133561 atacatccat gactaagagc ttcaccaagt ctgccatcta ttatataact tcctgttgaa
   133621 tcatatagta cagaatgata gtaatatcca cctttaattc tagtagcata cttaactgaa
   133681 tactcatccg ttccaaaaga aggttttctt ccacttatat aaaatatacc tgttatagtt
   133741 ggagtctcag gcttgcctat agtacattgc cacttgtaaa gttgtcccca tcctccatta
   133801 tctttcttaa aaatataagt atatttattt ctaaggtctg ttacaattag ataatcgcta
   133861 gtacttttaa tgttattttc gttaacaaat ttaatcatgt cagtataaaa atacttataa
   133921 tctaattcat ttggtttatt cccatcaatt gataaaaaat aattaaaaac atatcctatt
   133981 ttatcatcat atacaacctt actccaatct ccatctactt gaaggacttc aaccctagat
   134041 ttttcaggaa ttactgtaat tatattggaa gttgtagatt tatcttctct taagtttaag
   134101 ttactccaag catattcgct tactgatacc aaatccttat acacatatcc ttcttgagaa
   134161 ttgtacatca ccttaatcca gtcatcttct tcatccaata cttccatttt ggctccctga
   134221 ggtattactg ttatgatact tgaattagta gatttagcag acctcaaatt tacatttgct
   134281 aaagcatatt tatatatagg tgctctatat tttttaatat ttagtttagt taatttcaca
   134341 catatccatc ctctcatatg tctttttaca acattttatg aaattcgata tgtattcgtt
   134401 ctcctatttt caaactttac ttgtattact aagaatattg ctacatatac ttatatattc
   134461 tcacctatat ttatctattt atttaaattt atgatattac attctttaat atactcttca
   134521 attatacctc tagccacatt aaaataactt atacacttgt caactatgac tgcatcacta
   134581 ctaactactc tatctaattt ttccaataca acatctgcat tttttactaa ttctacttca
   134641 gtttcaattc cccaagtttt ggcatgctct aatatcctat actttaaatt tcctgaatta
   134701 gaaactggag catctaaata aaatttaaga ttctgtgcat tgtatttatt aaaaaattta
   134761 cctatcagat tcaaagcttc ttctgtttta tctataatct tataggttcc cctaagacct
   134821 gctaaatctc ttatattgcc atcacttcct attactagag taccaccaga taatgctacc
   134881 tctatggata ttatcaaatt aaagccatct atatttacgg tatcttcttt gattttatct
   134941 agagaaagcc tttttgattg tcttataata tttttttcat cagtacagac tgcccttttt
   135001 aatgcatctc tttgtcttat agaaaactga tatctatcac caacaaaagt aacgactggg
   135061 tctattttgt aatccctatt taataaccat tctatttctt ctttagactt tataagtctt
   135121 gttaattctt tacttgaaaa ccatctttta tcactatcat caaaccctct tttagatatc
   135181 ttatttatat catttcacca ccttgcttta aagatataac tgtactacat taaatacaga
   135241 ttatttcacc ttttaagata atttttaata ccattatctt atccatttag attattcaat
   135301 atttataatt aattataacg cttaacccca cttaataata cagaataata gattctatat
   135361 tatatttata agtttataac ataaataggt agtgttttaa aataaacttt ttagttcata
   135421 agataatctt cttttataaa atcaaatata tttttatcat ttaaacagta aaaaagagac
   135481 ttatctctat tttttgagat agcctctttc taaaatctac ttataatgat aattttaggt
   135541 ttatatatta aacttatgtt atacttcttt tatcatatta ggagatagaa tatcattaag
   135601 agcttctgtc atagttggat gtgcataaac acggtctctt aaatatgtat actctacttc
   135661 taaatctaca gctaattgaa taagatggat aatctcactt gaattttcac atatcatact
   135721 agctccaagt atcttattgg attttttatc tatcactatt tttataaacc catctgcctt
   135781 gccaatctgt ttagctcttg gaattgcttc tactggcatc tttgccacta atacttcata
   135841 tcccttttct ttagcttgtt taacattaag accaactctt gaaaatgctg gacttataaa
   135901 tatagaattt gggatattct ttctatcatt agttgttcta gtcttatctc caaacaactg
   135961 attaataact atgcgataat catccaatga gatataagta aattgtggac ctccatttat
   136021 atctcctata gcccatatat gctctttatt agtcttaaga gtttctgaga ctttaataaa
   136081 tcctctttca tttaattcta tacctgcatt ttctagccct agctcctcag tatttgcttt
   136141 tcttcctgta gctacaagta tcatattact tgttaattct ttagatttac catctacttc
   136201 atattctact attgctaatt cagaaacttc tttaatctct tttatatttg cattattaac
   136261 aatttttaca tttctctttg caagtaattt tattatttct tctgaatcct caacatcttc
   136321 atttggtaaa atgccattat tagagtttaa tattgtaact tctgctccaa atgaactata
   136381 aataccagca aattctaaac ctataaatcc agctcctata attgtcattt ttttaggtaa
   136441 agttcttaga ttcataagag actcactatc atatactata ttcttatttt caattccctt
   136501 aatattaggt ataaatggtc ttgaaccagt attaataaat atattatctg ctactaactc
   136561 ataaatttca ttttcagttt tgacttgaac tgttttttca tcaatgaaag ttcccattcc
   136621 tgtgaatata gttacattct catttgaatt taatttatta tagttagctt ctctgagttt
   136681 tgtaattaaa gtttcttttt tatctatagc tttctcatat tcagcttgta cttcatccca
   136741 agaatttata ttctttgttt ttacgctgtt tgctgaattt tctaagcttt ttgttggtat
   136801 acatgccaca tttacacatg ttccaccata catcttgttt gacttttcta ttaaagctac
   136861 ttttaatccc ctgtttgcca aatcccctgc taatgttttt ccaccttttc caaatcctat
   136921 tattatagca tcaaatgttt ttttcatata aaattcaacc ctttcttgta ttgtttatac
   136981 ttttactata acaagattat ttaggtggta caattaggca cttttttgta accttaaatt
   137041 gatttataaa cttatactta aatactttta tttatttctc tgattttcaa taaatgatgc
   137101 catagttgcc ttatccatag ctcctggaat atactgagtt acatatcctt ccttgtcaat
   137161 tataaatgta gttggaaaag cattaattcc atattgatat gctaatgctc catcttcatc
   137221 aagtacaaca gggaatgtat aaccttggtc ttttaagaag ttaactacat gttcccttga
   137281 accttctcta cctaaattag gtgaagctac tcctaaaatt actacatcat cattattttt
   137341 attatagtct ttatacagtt gttctatata aggcatttct tctttacatg gaggacacca
   137401 tgtagcccaa aaatttaaga atacaacttt gccttcataa tcacttaatt tatgtgtttt
   137461 accatactgg tctgttaaag taaaatcaat agactttatt ctatcttcat cattagaccc
   137521 tttatcatta ttgtcattat tagagtcttt ttgactatca ttaccatcag aattttcttc
   137581 tttatcagta gaattttctc gcttattttc ttcttgcttg ctttcaattt tactattttg
   137641 tgacgtatta aagtgtttgc ttatacttcc aaatccattt accatcatta atattcctga
   137701 tactataagt ataatcccac ctattttttt aataatttcc atgttagatt ttatcttatc
   137761 tatagtttta aatagtttac tgtaaaacat agctgtaatt atgaatggca aaataaaacc
   137821 aatagtatat actgctatta aaagattcgc actaagatga ttacttgaac ttgaaaccat
   137881 gactaataca gatgccaata ttggaccaat acaaggtgtc catccaaaac taaatgtaaa
   137941 acctaatata aaagctgtta ttgctttcat ttctttaaac ttaacattaa atcttttttc
   138001 tctattcaat attgaagatt taattattcc catgtaaaat aatcccatga taataattat
   138061 aatcccacca ataaacatta ttaaatcttt attttcatta aaaaacatac tcaatacttt
   138121 tactgatgaa cccaatataa agaatgttgt tgagattcca agagcaaaaa atatagtatt
   138181 tttaaataaa gaacttccta taaaactcgt ctttccttct tttaaatttt ctacactact
   138241 atttgacaat atactcaaat aaataggcaa aattggcagt atacatggtg aaaagaatga
   138301 tactatacct tctataaata ctaaaaataa atttacattt tgcaaattaa aattcctcct
   138361 tattttattt ccaatattac aatcccattt ctaaattaaa atctaactaa aaaattatgt
   138421 aattttaata catttttcta ctcatagctt aattaaattt tcattactta cagagtaaat
   138481 tttagtattt atcacaattt aaatttttat tgctccacat aatcattttt tccatgacag
   138541 gaagcaatcg taatcctgat tcacttaaaa aatatgttga ctctacaaca ttattaacca
   138601 actttttttg gttgactata atcccctgtt caattaaaaa atctagttgt tgaactaaca
   138661 ttttcttact acagtctggt atagctcttt gtagctctcc aaatcgtttt ttatcttctt
   138721 gtattttcca tataattata gccacccatt ttttacctaa aatatttgat aaagcttcta
   138781 ctggacaatt atatatcata tcatctatgt tgtacatttt attctcctct tttctttatt
   138841 taatttatta aacaaacttt tatagcaata tatttattaa tattataaat atacctagct
   138901 ttatttaatt aaaattttta ttatatatac tcctattaca aactatttta gattttatgt
   138961 aattaatata tcagttttgt aaatacataa caattggtaa cttttttgta actacatcaa
   139021 ctctattaat atacaatctt taactcattt
//
LOCUS       DAMJWC010000002       121681 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMJWC010000002 DAMJWC010000000
VERSION     DAMJWC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 121681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 121681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..121681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.002"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            219..2975
                     /locus_tag="PC503_000142"
     CDS             219..2975
                     /locus_tag="PC503_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526167.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDIIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            3107..3586
                     /locus_tag="PC503_000143"
     CDS             3107..3586
                     /locus_tag="PC503_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526168.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            3602..4024
                     /locus_tag="PC503_000144"
     CDS             3602..4024
                     /locus_tag="PC503_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2526169.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            4064..4855
                     /locus_tag="PC503_000145"
     CDS             4064..4855
                     /locus_tag="PC503_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526170.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            4848..5648
                     /locus_tag="PC503_000146"
     CDS             4848..5648
                     /locus_tag="PC503_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2526171.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            5696..6751
                     /locus_tag="PC503_000147"
     CDS             5696..6751
                     /locus_tag="PC503_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2526172.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(6930..8876)
                     /gene="feoB"
                     /locus_tag="PC503_000148"
     CDS             complement(6930..8876)
                     /gene="feoB"
                     /locus_tag="PC503_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2526173.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(8894..9112)
                     /locus_tag="PC503_000149"
     CDS             complement(8894..9112)
                     /locus_tag="PC503_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2526174.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            9318..9827
                     /locus_tag="PC503_000150"
     CDS             9318..9827
                     /locus_tag="PC503_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2526175.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            9905..10066
                     /locus_tag="PC503_000151"
     CDS             9905..10066
                     /locus_tag="PC503_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2526176.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            10217..10882
                     /locus_tag="PC503_000152"
     CDS             10217..10882
                     /locus_tag="PC503_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2526177.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            10948..12732
                     /gene="pepF"
                     /locus_tag="PC503_000153"
     CDS             10948..12732
                     /gene="pepF"
                     /locus_tag="PC503_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2526178.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            12984..13826
                     /locus_tag="PC503_000154"
     CDS             12984..13826
                     /locus_tag="PC503_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2526179.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      14059..14142
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            14722..15399
                     /locus_tag="PC503_000155"
     CDS             14722..15399
                     /locus_tag="PC503_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526180.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            15471..17486
                     /locus_tag="PC503_000156"
     CDS             15471..17486
                     /locus_tag="PC503_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2526181.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLYFL"
     gene            17536..18216
                     /locus_tag="PC503_000157"
     CDS             17536..18216
                     /locus_tag="PC503_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526182.1"
                     /translation="MQTKILIIDGDKDNCKKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            18734..19180
                     /locus_tag="PC503_000158"
     CDS             18734..19180
                     /locus_tag="PC503_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526183.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIHTYCKHQVS"
     gene            19561..20478
                     /gene="pstC"
                     /locus_tag="PC503_000159"
     CDS             19561..20478
                     /gene="pstC"
                     /locus_tag="PC503_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2526184.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            20480..21304
                     /gene="pstA"
                     /locus_tag="PC503_000160"
     CDS             20480..21304
                     /gene="pstA"
                     /locus_tag="PC503_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2526185.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            21323..22087
                     /gene="pstB"
                     /locus_tag="PC503_000161"
     CDS             21323..22087
                     /gene="pstB"
                     /locus_tag="PC503_000161"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2526186.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            22115..22768
                     /gene="phoU"
                     /locus_tag="PC503_000162"
     CDS             22115..22768
                     /gene="phoU"
                     /locus_tag="PC503_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2526187.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            22926..23795
                     /locus_tag="PC503_000163"
     CDS             22926..23795
                     /locus_tag="PC503_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2526188.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            23882..25318
                     /locus_tag="PC503_000164"
     CDS             23882..25318
                     /locus_tag="PC503_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2526189.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     NLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            25366..26193
                     /locus_tag="PC503_000165"
     CDS             25366..26193
                     /locus_tag="PC503_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2526190.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    26489..26751
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            26827..29493
                     /locus_tag="PC503_000166"
     CDS             26827..29493
                     /locus_tag="PC503_000166"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2526191.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            29918..30628
                     /gene="rgaR"
                     /locus_tag="PC503_000167"
     CDS             29918..30628
                     /gene="rgaR"
                     /locus_tag="PC503_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2526192.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            31674..32705
                     /locus_tag="PC503_000168"
     CDS             31674..32705
                     /locus_tag="PC503_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2526193.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            32838..34136
                     /locus_tag="PC503_000169"
     CDS             32838..34136
                     /locus_tag="PC503_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2526194.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(34250..34495)
                     /locus_tag="PC503_000170"
     CDS             complement(34250..34495)
                     /locus_tag="PC503_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2526195.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            34643..35509
                     /locus_tag="PC503_000171"
     CDS             34643..35509
                     /locus_tag="PC503_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2526196.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(35513..36049)
                     /locus_tag="PC503_000172"
     CDS             complement(35513..36049)
                     /locus_tag="PC503_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2526197.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(36240..36443)
                     /locus_tag="PC503_000173"
     CDS             complement(36240..36443)
                     /locus_tag="PC503_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2526198.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            36734..37498
                     /locus_tag="PC503_000174"
     CDS             36734..37498
                     /locus_tag="PC503_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2526199.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            37887..39200
                     /gene="prdC"
                     /locus_tag="PC503_000175"
     CDS             37887..39200
                     /gene="prdC"
                     /locus_tag="PC503_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2526200.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      39605..39690
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            40272..42446
                     /locus_tag="PC503_000176"
     CDS             40272..42446
                     /locus_tag="PC503_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDF2526201.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQTPDVEKPSDGQ
                     MPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERL
                     KQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTGEVE
                     ISTQQKFKLKSVVKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPP
                     MDDTIINPPVPPTEDAVLNPPVPPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPE
                     LSRDDTIIKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            42853..44613
                     /gene="prdR"
                     /locus_tag="PC503_000177"
     CDS             42853..44613
                     /gene="prdR"
                     /locus_tag="PC503_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2526202.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            45042..46922
                     /gene="prdA"
                     /locus_tag="PC503_000178"
     CDS             45042..46922
                     /gene="prdA"
                     /locus_tag="PC503_000178"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2526203.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            47003..47287
                     /locus_tag="PC503_000179"
     CDS             47003..47287
                     /locus_tag="PC503_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526204.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            47325..48050
                     /gene="prdB"
                     /locus_tag="PC503_000180"
     CDS             47325..48050
                     /gene="prdB"
                     /locus_tag="PC503_000180"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:47775..47777,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2526205.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            48130..48888
                     /gene="prdD"
                     /locus_tag="PC503_000181"
     CDS             48130..48888
                     /gene="prdD"
                     /locus_tag="PC503_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2526206.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            48903..49370
                     /locus_tag="PC503_000182"
     CDS             48903..49370
                     /locus_tag="PC503_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2526207.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            49388..49870
                     /locus_tag="PC503_000183"
     CDS             49388..49870
                     /locus_tag="PC503_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2526208.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            49890..50897
                     /locus_tag="PC503_000184"
     CDS             49890..50897
                     /locus_tag="PC503_000184"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2526209.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            51017..51898
                     /locus_tag="PC503_000185"
     CDS             51017..51898
                     /locus_tag="PC503_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2526210.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            52566..53201
                     /locus_tag="PC503_000186"
     CDS             52566..53201
                     /locus_tag="PC503_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2526211.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            53385..53954
                     /locus_tag="PC503_000187"
     CDS             53385..53954
                     /locus_tag="PC503_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2526212.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            54032..54169
                     /locus_tag="PC503_000188"
     CDS             54032..54169
                     /locus_tag="PC503_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526213.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            54166..55941
                     /locus_tag="PC503_000189"
     CDS             54166..55941
                     /locus_tag="PC503_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526214.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            56366..57673
                     /locus_tag="PC503_000190"
     CDS             56366..57673
                     /locus_tag="PC503_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2526215.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            58001..58540
                     /gene="hpt"
                     /locus_tag="PC503_000191"
     CDS             58001..58540
                     /gene="hpt"
                     /locus_tag="PC503_000191"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2526216.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            58918..60594
                     /gene="bclA2"
                     /locus_tag="PC503_000192"
     CDS             58918..60594
                     /gene="bclA2"
                     /locus_tag="PC503_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF2526217.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(61101..61856)
                     /locus_tag="PC503_000193"
     CDS             complement(61101..61856)
                     /locus_tag="PC503_000193"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2526218.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            62296..63285
                     /locus_tag="PC503_000194"
     CDS             62296..63285
                     /locus_tag="PC503_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF2526219.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(63737..64453)
                     /gene="dapD"
                     /locus_tag="PC503_000195"
     CDS             complement(63737..64453)
                     /gene="dapD"
                     /locus_tag="PC503_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF2526220.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(64677..65426)
                     /locus_tag="PC503_000196"
     CDS             complement(64677..65426)
                     /locus_tag="PC503_000196"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2526221.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(65493..66380)
                     /locus_tag="PC503_000197"
     CDS             complement(65493..66380)
                     /locus_tag="PC503_000197"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2526222.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(66497..67498)
                     /locus_tag="PC503_000198"
     CDS             complement(66497..67498)
                     /locus_tag="PC503_000198"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF2526223.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(67923..68804)
                     /locus_tag="PC503_000199"
     CDS             complement(67923..68804)
                     /locus_tag="PC503_000199"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2526224.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            69127..70320
                     /locus_tag="PC503_000200"
     CDS             69127..70320
                     /locus_tag="PC503_000200"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF2526225.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            70526..71644
                     /locus_tag="PC503_000201"
     CDS             70526..71644
                     /locus_tag="PC503_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF2526226.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            71775..72020
                     /locus_tag="PC503_000202"
     CDS             71775..72020
                     /locus_tag="PC503_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF2526227.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            72007..72753
                     /locus_tag="PC503_000203"
     CDS             72007..72753
                     /locus_tag="PC503_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2526228.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            73038..73913
                     /gene="hslO"
                     /locus_tag="PC503_000204"
     CDS             73038..73913
                     /gene="hslO"
                     /locus_tag="PC503_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF2526229.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            74304..75104
                     /locus_tag="PC503_000205"
     CDS             74304..75104
                     /locus_tag="PC503_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2526230.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            75632..77872
                     /locus_tag="PC503_000206"
     CDS             75632..77872
                     /locus_tag="PC503_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2526231.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            78286..79821
                     /locus_tag="PC503_000207"
     CDS             78286..79821
                     /locus_tag="PC503_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2526232.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            79837..80598
                     /locus_tag="PC503_000208"
     CDS             79837..80598
                     /locus_tag="PC503_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526233.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            80936..81805
                     /locus_tag="PC503_000209"
     CDS             80936..81805
                     /locus_tag="PC503_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2526234.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            82134..82385
                     /locus_tag="PC503_000210"
     CDS             82134..82385
                     /locus_tag="PC503_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF2526235.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            82497..83276
                     /locus_tag="PC503_000211"
     CDS             82497..83276
                     /locus_tag="PC503_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2526236.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFINYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(83411..84061)
                     /locus_tag="PC503_000212"
     CDS             complement(83411..84061)
                     /locus_tag="PC503_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526237.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(84058..84561)
                     /locus_tag="PC503_000213"
     CDS             complement(84058..84561)
                     /locus_tag="PC503_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2526238.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(84610..85125)
                     /locus_tag="PC503_000214"
     CDS             complement(84610..85125)
                     /locus_tag="PC503_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2526239.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            85405..85932
                     /locus_tag="PC503_000215"
     CDS             85405..85932
                     /locus_tag="PC503_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2526240.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            85916..87319
                     /locus_tag="PC503_000216"
     CDS             85916..87319
                     /locus_tag="PC503_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2526241.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(87702..88013)
                     /locus_tag="PC503_000217"
     CDS             complement(87702..88013)
                     /locus_tag="PC503_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526242.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(88069..88662)
                     /locus_tag="PC503_000218"
     CDS             complement(88069..88662)
                     /locus_tag="PC503_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2526243.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            89513..90163
                     /locus_tag="PC503_000219"
     CDS             89513..90163
                     /locus_tag="PC503_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2526244.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            90377..91048
                     /locus_tag="PC503_000220"
     CDS             90377..91048
                     /locus_tag="PC503_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526245.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            91045..92175
                     /locus_tag="PC503_000221"
     CDS             91045..92175
                     /locus_tag="PC503_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2526246.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKLEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            92595..93440
                     /locus_tag="PC503_000222"
     CDS             92595..93440
                     /locus_tag="PC503_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526247.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            93440..94468
                     /locus_tag="PC503_000223"
     CDS             93440..94468
                     /locus_tag="PC503_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526248.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            94471..95484
                     /locus_tag="PC503_000224"
     CDS             94471..95484
                     /locus_tag="PC503_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526249.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLYYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLF
                     FSR"
     gene            complement(96001..97251)
                     /gene="cme"
                     /locus_tag="PC503_000225"
     CDS             complement(96001..97251)
                     /gene="cme"
                     /locus_tag="PC503_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF2526250.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(97337..98083)
                     /locus_tag="PC503_000226"
     CDS             complement(97337..98083)
                     /locus_tag="PC503_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2526251.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(98198..99220)
                     /locus_tag="PC503_000227"
     CDS             complement(98198..99220)
                     /locus_tag="PC503_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF2526252.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTYSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(99220..101640)
                     /locus_tag="PC503_000228"
     CDS             complement(99220..101640)
                     /locus_tag="PC503_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2526253.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSYNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(101726..102646)
                     /locus_tag="PC503_000229"
     CDS             complement(101726..102646)
                     /locus_tag="PC503_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2526254.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            103276..104202
                     /locus_tag="PC503_000230"
     CDS             103276..104202
                     /locus_tag="PC503_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2526255.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(104391..105011)
                     /locus_tag="PC503_000231"
     CDS             complement(104391..105011)
                     /locus_tag="PC503_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526256.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(104983..106566)
                     /locus_tag="PC503_000232"
     CDS             complement(104983..106566)
                     /locus_tag="PC503_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2526257.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(106710..108737)
                     /locus_tag="PC503_000233"
     CDS             complement(106710..108737)
                     /locus_tag="PC503_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526258.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTRILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKK"
     gene            complement(108750..109499)
                     /locus_tag="PC503_000234"
     CDS             complement(108750..109499)
                     /locus_tag="PC503_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526259.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(109798..111450)
                     /locus_tag="PC503_000235"
     CDS             complement(109798..111450)
                     /locus_tag="PC503_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF2526260.1"
                     /translation="MNKKNLAILISGIMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            112038..113159
                     /locus_tag="PC503_000236"
     CDS             112038..113159
                     /locus_tag="PC503_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2526261.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            113195..113608
                     /locus_tag="PC503_000237"
     CDS             113195..113608
                     /locus_tag="PC503_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2526262.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            113601..114140
                     /locus_tag="PC503_000238"
     CDS             113601..114140
                     /locus_tag="PC503_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2526263.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(114340..114825)
                     /locus_tag="PC503_000239"
     CDS             complement(114340..114825)
                     /locus_tag="PC503_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526264.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            115730..116107
                     /locus_tag="PC503_000240"
     CDS             115730..116107
                     /locus_tag="PC503_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2526265.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            116503..118308
                     /locus_tag="PC503_000241"
     CDS             116503..118308
                     /locus_tag="PC503_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526266.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            118385..118924
                     /locus_tag="PC503_000242"
                     /pseudo
     CDS             118385..118924
                     /locus_tag="PC503_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            119547..120761
                     /gene="dpaL"
                     /locus_tag="PC503_000243"
     CDS             119547..120761
                     /gene="dpaL"
                     /locus_tag="PC503_000243"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2526267.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            121091..>121681
                     /locus_tag="PC503_000244"
     CDS             121091..>121681
                     /locus_tag="PC503_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2526268.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT        46625 a        14258 c        20734 g        40064 t
ORIGIN      
        1 tacaataaat atattcttat ataaattcta tgtcagatat atggaaagat aagaaccttg
       61 agattatgtt aaaaaatcta gattttatac ttataaaaag tttgatttta caaacttaca
      121 aaagagaatc aagataggaa tataattatc tttttcataa atatataaat gatatactaa
      181 tattatagta ttattgatat ttgtattgga ggttgaacat gagggatgaa attttaagtt
      241 ttgtaaatga atgtgtatta tttaacaact ttgatgaact taaaaaagaa agtggcataa
      301 taacagaaga tatagtaaaa aagtttaatt taagtagaac tcaatcaagt agattattaa
      361 atgatttagt aaaatctgat aatcttataa agataaacag tagacctgtt atttttttac
      421 ctaaaaataa aataaatgat gtagtaggac ctacaaaaaa aagtatttat gaaaatttag
      481 atgaacttaa aaatgagtgt aaattattaa agcaagagac tgtgtttaat agtatcatag
      541 gatatgataa tagcttaaaa gaagtaatcg aacaaataaa aaccgctgta ctttatccaa
      601 atggcggact tacaataatg ctgacaggtg aaagtggagt aggaaaaact tttttagcca
      661 agataatata caaatatagt gtaagcagta atgtattaga aaaaaattct ccatacaatg
      721 tgttaaactg tgcgcagtat tataataatt tggagttatt gtctagtcta ttatttgggc
      781 atgtaaaagg agcatatact ggagcaaatg aatctagagc aggtctaata gaacaatcag
      841 atggtggtgt tttattttta gatgaagtac atagattaaa tagtgaaggt caggaaaagt
      901 tatttacatt tatggataca ggtacgtttt ctaggattgg agagaatgga gtaattagaa
      961 aagctagggt aagattaata tttgctacaa cagaaagtct atctgaattt ttacaaacct
     1021 ttttaagaag aatacccata aatatttatg ttcccaatat agaagaaaga gggactattg
     1081 aaaaaagaaa gattgtagaa cattttattt atgaagaaag taaggtactt ggtttgccta
     1141 tagagataac tcaaattaca ttaaatgcga ttttaaagat aaaattcaag gggaatatag
     1201 gtgaatgtaa aaatgtaata aaatatgcat gtggacgagc ttatgcaaaa aatcaaagaa
     1261 gaaatggaaa tatttttgtt actcttcaag accttcctag aaatctttat atagaaaatg
     1321 tagatatatt tcaattccaa agtggtaaaa gcaaaagcat tatcttttct cctaaacaat
     1381 ttagtattga aatgtcaaat ggaagaaata aaagaaatat aatctatcaa agtttcataa
     1441 aatgtttaga ttactttgat agactagaaa aaaatgaaat aacaaaggaa aaatttagta
     1501 aaaagagttc taatctaatg attagactaa tggacaattt agtcttttca aataatgatg
     1561 aaaataataa cgtacttatg gagcttataa tatcgataat gcaggatata tttagaaatt
     1621 tagaagttaa taacaatata aaatatgatg ggaataatgt attggcattt tcgtcttatc
     1681 tttatttgaa ggacgaatct tatcaattgt ctgatgagta taaagcttta gaaaataaat
     1741 tactaatata tttaaaaaaa gagagttaca aagaatactc tataataagt aaaatatcaa
     1801 cattaataac gaatagattg gatatgtatc ttaataatgt agatataatc ataatgatta
     1861 tatttattaa atcaacaatt ataagaatga aatttaatca agttaatgcg actattatag
     1921 cacatggata tgctactgcc agtagtatgg cgaatgtatg taatcggatg ttgggtaaaa
     1981 atatatttac agctattgat atgcctatag atgctactat tgcggatgta tcaaaacaaa
     2041 tgtctagata cctagaggga gataggataa agaatggttt aattgtgtta tttgatatgg
     2101 gctctcttaa tcttatatat gaagatttaa agaataagat aaatagccca atgttattta
     2161 tagaccaaat atccactatt tctgcactag aagtaggaaa tttattaatg caaggtaaaa
     2221 acattgaaga gattgcagaa attatggatg aagaaactaa acctaatata caattgtatt
     2281 atcctcaaaa aaataaagaa tatgctataa tatcatcttg ttttacaggg ataggtactg
     2341 ctataaaaat ccaacatcta ctttccgaaa gtttaattgg aatagttgat gtcaaaataa
     2401 taccttatga ttatgatagt cttgtttcta tgggagataa agaaccagtt tttgaaatgt
     2461 atgatgtgat ggctatagta ggaactgcca atccaaatgt gaatggggta gattttatat
     2521 tattagagga tataatatca ggaaaaggag aagatgatgt ttttagaata tttagcagag
     2581 tagtagaaaa tgaaaaaata aagaacataa atgattctat tgtaaagaat ttttcattaa
     2641 ttagagtaat agatagtcta actattttag attcaaaaaa gataatagag agaatagaag
     2701 aaggaattaa tgctatagaa aatattcaaa agaaaaaact ttcaaatgat aaaaagattt
     2761 ctttatatgt tcacttaagt tgtatgattg aaagattagt tagacaaact gaaattgaag
     2821 agtatactga tatggatttg ttaatcaaaa accatcatag tgaagtaaaa ctaataaaaa
     2881 atgcatttag tgtgctagaa aagagttata gtgtgcaaat accaatttca gagataggat
     2941 atatttataa tattatctat ggtctaccac agtaaaatac aagattacaa aataagtgaa
     3001 tgaaatttaa aaaagtatgc cagtatttgg catacttttt gcttttatag ataaatgaga
     3061 gtataaacaa taaaaatttt aatgtatgat ggaggatttg gggaaaatgg tatctttgat
     3121 gagaattgat gacagattga tacatggtca ggttgcatat ggatgggcaa catcactagg
     3181 tataaatgta atactagttg caaatgatga agcaaaaaat gaccaaatga aagctatgtc
     3241 actgaactta gcgaaaccta gcaatgtaac tttatatata aggggggtag aggaatctgg
     3301 agaaatagta gaaaaatttg cttcttcaaa gaaaagcaat gtattagtgt tagtaaaaaa
     3361 taccaaagat gctttagttg tagctaaaaa ttcaggagga gtattaaaag aaataaatgt
     3421 aggaggatta agatatgagg aagggaagaa gaaacttaca gatttagttg ctgttgatga
     3481 tgatgatata aataacttta aacaaatagg tgatttaggg attgatatag aatttagaat
     3541 gttacctaga gacaaaaaga aacaactatc agatttaata aaataattta ggagaaagag
     3601 aatgaaaaaa tttctaattg caacacatgg agaattgtcc agagagcttg ttgacacaag
     3661 taaattaata attggttcat taactaatat tgagtatttt tgtatgacaa cggataaatc
     3721 agcagatgat gctgagaaag aaattagaag tatattatca aataataaag atagtgaaga
     3781 atttgttgtc ttaacagatg tttttggtgg aagtgtggca aacatatgta caaacttact
     3841 tttacaaggg ttcaaatttg aattattgac aggagtaaat ttaccaatgc ttttatctat
     3901 acttttatta gttgaggagg atacaaaact aatagttaaa tcaggattag aggaagcaaa
     3961 aaatggaatt gtttatgtaa atgagttatt agaaaatcaa aacaaaatca aaaatgtaat
     4021 gtaatttaat gtaaattaaa ctaagttaaa atggaggttc aatatgttag tacaagctac
     4081 tatgttagct attatagcag gagttggtat actagatggg cgtatatttg gtcaatctat
     4141 gcttgatagg ccaatagtta caggtatgtt agtaggatta gttttaggag acataaaatc
     4201 aggaattatg attggtgcac agcttgaatt aatttggatg ggaattgcag gaataggtgc
     4261 agctactcct ccagatgtag taacaggagg tgtattaggt acagcttttg ctatattatc
     4321 aggtaatggt gcagaagttg ctttagcagt agcagtacca gtagcagtct tagcacaatc
     4381 tcttggagta ttagttagaa taataaattc gtacttttct caaaaggcag ttttctatgc
     4441 taaacaagct gattttaaga aagttaccat aatgatgtgg ttgccagtaa tattattctt
     4501 tttaagtaca tcagttccaa cctttttagc aattatgatt ggtgctgata aagttacagc
     4561 attgataaat gcaataccta aagttatatt agacggactg ggtgttgcag gaacattgtt
     4621 gccagcagta ggttttgcat tgcttatgga tatgttactt tcaaaaaaga tgtctgtatt
     4681 tttctttata gggtttttgt tagcatctta tggtggatta gatataactg ctatagcttt
     4741 atttggagta tgtgtagcat ttgtactaaa cttttatatc aataacaaag aaaataatca
     4801 aaatcctcaa ttagcaatca atactttaac ggaaggagag attgactttg aataaattaa
     4861 caaaaaaaga attaagaagt atgttttggc gttcatttgc tcttcaaggt gcatttaatt
     4921 acgaaagaat gcaaaactta ggttactgtt attcaatgtt acctgcaata aagaagctat
     4981 acaataagaa agaaaatcaa gcaaaagcaa tagaaaggca tttggagatt tttaatacaa
     5041 cgacagtagt agttcctgct atattaggta taacagcagc tatggaagaa gagaatgcta
     5101 ataatccaga atttgatgaa agttcaatta gtgctgttaa aacagctctt atgggacctc
     5161 ttgcaggaat tggtgattca ttattctggg gaacatttag gattatagca gcaggagtag
     5221 gagtatcact tgcaaaagaa ggtaatatct ttggaccact attattctta ctattataca
     5281 atataccagc atttgccctt agaatatttg gacttaagta tggttatcaa gtaggggtaa
     5341 attctcttga aagaatacaa agagagggac ttatggagaa aataatgtct atggctacaa
     5401 ctgttggttt attcgttgta ggaggaatgg ttgcaactat gttgagtata actactcctc
     5461 tgaaattcaa cttaaatggt gcagaagtaa ttttacaaga tatactagat aaaataatac
     5521 ctaatatgtt acctttaacc tttgcatttg taatatacta catgttaaag agaaaggtaa
     5581 gtgtaacaaa attaactata ggcactatag taacaggaat cgctttacat gctataggtt
     5641 tgttatagaa attaattata atttattgaa tatatagata aggaaggtgt ataaaatgac
     5701 aatacaagat tatatgttag aaacaccagt tagaatgaga gaaattatat ctaatgcaga
     5761 tagcttattt aatgaagtta agagaacaaa tctaaaaaag attataataa caggttcagg
     5821 tactagctat cactcaggag tgcaagtaca accatattta caaaatttat tagatataga
     5881 tgttgtgaaa atgtatccat ttatgataac tgaagataca ttcaagtttg ataatgaaaa
     5941 taccctagta gtaggtgtat ctcaaggtgg gagtagttat tctacataca acgctatgaa
     6001 gttagctgaa gataagggct gtaaaatagc atctatggca ggttgtaaga atgctttaat
     6061 agatgagatt tctgattata tattaacagt aaattgtggt gaagaaaaat ctggagctaa
     6121 aacaaaagga tattattgta caaagttaaa cttaatgtta ttaggtcttc aaatagctag
     6181 agaaaaaggt ataatatcta gtgaaaagta caatgaggaa ataaataaga tattagacgc
     6241 aattaataga tttgaagcag tgtataagct ctctaaacaa tggattgaaa gaaacaaaga
     6301 aaagttagtt aattctaaag aaataagaat aataggtcac tctgatatat atggagatac
     6361 attagaagca gcattaaaat tattggaaac aatgagaata cctgtaactg ggtatgagtt
     6421 tgaagagttt atacatggta tatataatgc tataaatagt gattctacta tatttatact
     6481 agatacagga aaagaaccta gagtaactaa gatgattgat gtactttctg gttggacgga
     6541 aaatgtattt gctataggta gagatgttac agaaaatgat aaaaatttaa agattgatat
     6601 cacagataat ccttactatc aaacatttaa ttttatagta cctatacaac taatatgtgg
     6661 ggaaatacct acattaagag gtgtagaccc aagtgttcca aaagatacta ggttccacat
     6721 gaagttaggt agcaagaaac tgaataagta acaaaaaaag aggttgtctc aaaatagaga
     6781 taagcctctt ttttactaga taagctcttt tttactgttg aaatgatgaa aatatatttg
     6841 attttctata aaaaagagtg cctcatgaac taaaaagtta attttgagac acccactttt
     6901 atcttatttt aaactaaaat atttatatat tagtgtgcat tatttttttt attgctgtct
     6961 tccttacttg agcaagaatt agcacttgga catccagaac aaatagaaca tccactacag
     7021 acatttccgt tttttgtaga cttgaattta ttaaacagaa taaagagtgc aaggactata
     7081 attattccac ctatcaaagc ttctattatt gaattaccca taaatagtac tccacctata
     7141 cttttaacta taaaagccat tatccatgct agtataaatt gatatgcaaa tgatgtaaac
     7201 atcattttat tgccatattc ttttttcata gttgcaagtg cagctataca tggagtatat
     7261 aaagcagtaa atatcaagaa tgtatatgca gtaactccat taaatattgt tggtaagaca
     7321 acagttagat taccatatag tatatttaaa gagtttacta cgatttcttt tgctccaaga
     7381 ccacttaaaa tagcaactga agttctccaa tcatcaaaac caagaggttt gaatatagga
     7441 gatataatat gacctagagt agccaagaag cttacattta tatcttctgt atatccaaaa
     7501 acattgaatg aagaaagtcc ccaaattacg actgacattg caaacatgac agtaacaact
     7561 cttatcaaga aaccttttga tttattccaa gtatttttaa taagtgcatc tatagtaggg
     7621 attctatatt ctggtaattc taatataaat ggttcagcct ctgttttaaa ggctgtttta
     7681 tttaagaata atgcaactac aattgccata actataccca ccaaatacag tgatgtagtt
     7741 actaaagcag cattatgtgg aaagaatata gctacaaata gtgcatatat aggtagcttt
     7801 gctccacaag tcataagtgg tgcaataaga gctgtaactc ttctatcttt ttcgctttcc
     7861 aatgttctag ttgccattat agctggagaa gaacatccca tacccataac tataggtata
     7921 aaagctttac cagatagacc aacctttctc ataactttat ccattaaaaa tgctgttctt
     7981 gacatatatc cactatcttc aaacaacgat ataccaaaga ataatgtaaa tattaaaggg
     8041 aagaatggta aagtaccacc aacacctcca attattccat caactataag tgatttaaac
     8101 catgggctag agttagataa catatcacta acaggtgcag aaatataagc ctctataaga
     8161 ctagcaaatc cctcttgtag tggtcctccg acccagtcaa aggtaaattt aaataagagg
     8221 aacaatacac caataaatat cggatatgct aatataggat tcaagactat attgtctatc
     8281 ttatcactga tagatttctt ttgtgtatat gtagtttttg tacatctcga taaaatggat
     8341 tctaattttt tatatgtttc tgtttcactt ccaaagtttt tctgatatat aaaagctttt
     8401 tgcgtagctc ccttaatctc ttcttctatc ctatcaacac catttttctt ttttgctata
     8461 attggaacaa caattactcc aagttcttca cttaattttt tggcatctat attaactcct
     8521 ttagattctg caatgtctaa catattaagc aatataacta taggcttgtt aaattgcata
     8581 agttgagttg ttaagtaaag gtttcttgat aaattagaag catcaactac atttactatt
     8641 acatcaacat cttcattttc taaatatgat ttagaaacct tttcttcatt tgagaaagta
     8701 tccattgcat atataccagg taaatcgaca acctttatct cttttccaag aaatccttct
     8761 tttttttcta tagtaacacc aggccagtta cctacatatt gatttgaacc tgtaagtaga
     8821 ttaaaaacag tagttttacc gacatttggg tttcctaata atgctacatt aatcacgggt
     8881 agctcctcct ctattattgt aaagaaatat ttttagcatc agattttcta atcgcaaggt
     8941 caaagcctct aaatctaatt ataattgggt ctccaagtgg ggcaaccttt ttaacttcta
     9001 tttcagtact atttatacat ccaagtgcaa gcaatctttt agataattta atatctccat
     9061 ctatactatt aataaatcct ttttctccta tttttaaatc gtaaacagtc attattaaca
     9121 cctcctaatg aaattcatta tcattaaaat tgtaacaagt atgatacaaa aagtcaagat
     9181 ttatagaggt aattgcacat tgaaataact aatatttatt ctaaatagat taaaaatatt
     9241 ttagtctaaa ttaggtgttt ttatatattt tgtattataa tgtaagatga tagataaaat
     9301 ttggaggagt taacttaatg aaaactagaa aaatgacatt tttaggtctt atgatagggt
     9361 atagtttagc tttatatgta ttagagacat atataccaaa tcctcttata gttatatttc
     9421 caggggcaaa attgggtttg agcaatatta taactttaat ttcattaatg ttgttaggtg
     9481 tcaaagatac tgttataatt gttactatca gggtaatttt gtcatcaata tttgcaggcc
     9541 ctttatcata tctactattt agtataggag gagcttatct gagtctttta tttatgtatt
     9601 tagcgagtaa aataaaagat ttatcactaa tagggataag cattataggt gcaatagggc
     9661 ataatatagg tcaattaata gttgcaagtt taatcataga aaatatactt gctatagggt
     9721 acttaccatt tatgttaatg gcatcattag taactggtat gtttgtaggc ttagtatcca
     9781 ggtatacaat acctaaatta aagcattttt atagtaagtt ttattgacat aatattgaca
     9841 aaatataata ttgtttgata aaatgtatat aaaaatatac aaatttgtaa tagtggtgat
     9901 tattatggcg aacaatgaat tagaagcgtt aaaaaatgag attgaagcag ttagggaaga
     9961 gataaataca tacatagaat atccagaaat atttcaagaa gagttagtag aatcaagtaa
    10021 gaaaatagat atattaataa ataaatacat gtacctaagc aaatagccca cagttgtggg
    10081 tttttttgta tcaaaaatta acagatggct atattttaca tatattaata ataatattaa
    10141 gatataaaat agtatttctg atgtgtaaat tatctgtagg acataagttg taattaagtc
    10201 aggagggttt tatattatga ttgatatagg aagtaaggag atagcaataa ggttactatt
    10261 agcactaata ataggaggaa taataggctt agagagagaa aaaataagac agtttgcagg
    10321 atttaggaca catatactaa ttgcaatagg ttcttgtatt gtttcaataa cttcgattca
    10381 attattcttt gattataatt tgtatacaaa tgctgaccca gcaagaatgc ctgctcaagt
    10441 attatctgga attggttttt taggtgcagg agcaatttta aaaaataaag gtggagtaaa
    10501 agggcttact acagctgctg ggatgtgggc aactgcatgt attggtatag cagttggata
    10561 tggttattat gaattggcaa ttctaggtgg attatttgta atgatagcat tatttgtgct
    10621 taggataatc aatacgtttt tatttagcca agaaaagaat gtattgatat taaaattaag
    10681 caatttggat tctatacctt ttttatatga taaatttgaa aaaaatcaac ttatcgtaag
    10741 aaatatggaa atagaatgtc gtaatgaaga atactggaag gttaattttt ttgtatctta
    10801 tgctaagaga atacacttac acgacgttat gaaagaaata aatatgatag aaggagtaat
    10861 aaatgtagat tatttggact aaaatatata caatatattt tgtaaagtga ataaaatata
    10921 aaacaaatta aaatagaggt gtatgatatg ggaactgata gaagtacaat agaagaaaag
    10981 tacaaatgga agatagataa gatgtactcc agtaaagagg aaattgaaaa agacataagt
    11041 aaagtaaaaa atcttatcca agaagtaaaa gaatataaag ggaagctttc tgagagtaag
    11101 gagaacttat ataaagtatt aaatatctct gaaaatgcat ctaggattgt tcaaaattta
    11161 tatgtatata ctcatatgaa acaacatgaa gatactagaa ttaatgataa tcaaggaaga
    11221 gccactaaga cagaaatgtt atctactgat ttaggtgtgg ctacttctta tatagttcca
    11281 gaaatactgg cgatagaaga gaataagtta agtgaatact taaaagatga gaagctatcc
    11341 ttttatgcaa aatatataaa ggatatattg agagataaac cacatacttt gagtgaacga
    11401 gaggaagaaa tacttgcagc tacatcagaa ttatcgacaa ttccagaaaa tgtatacgat
    11461 atgttagcat atgcagatat ggaatttcct gagatagaag atgaggaggg gaataaggtt
    11521 aagctttctc attcaaacta ctctttattt ataaaaagta agaatagtag agttagaaaa
    11581 gacgcttttg aaggtgaatt ttcaacatat gagaaatata aaaatacatt tgcctcaacg
    11641 ctttatggtg gaataaaatc agagatattt tacgcaaaaa ctagaaagta taattcagca
    11701 atagaagcgt ctttattttc agatgatgta agtttagatg tttacaataa tcttatatca
    11761 gctatagata aaagtattcc taatctaaat aaatatgttg agcttaaaaa gaaattttta
    11821 ggattgaatg aaatacacat gtatgatttg tatgttcctt tgacagataa atttgacatg
    11881 gatataccat atgataaagc acaggatatc atattagagg cacttaaacc tttaggagaa
    11941 gaatacttga aggtcataaa aagtgctttt gatgaagggt ggattgatgt atatgataat
    12001 gaaggtaaaa aaggaggagc ttattcttgg ggaagttatg attcacatcc ttatatatta
    12061 atgagctata aaaatgacct taattctcta ttcactttaa ttcatgaatt agggcactct
    12121 gttcacagtc attattcaag aacaagtcaa ccatttttat attcggacta taagatattc
    12181 gttgcagaag ttgcatctac attaaatgaa ttacttctta taaattattt attagaaaat
    12241 tctaagtcta aggatgaaac tatatactta ttaaattatt atttagaaca atttagaact
    12301 acagttcata gacaaactat gtttgctgaa tttgaaaaaa ttgtacatca aagggtagag
    12361 agtggagaac cacttactgc tgatgaattt actaatatat actacaaatt aaatgaaaag
    12421 tattacggaa aatctgcaat agtagataaa caaataggaa tagaatgggc gagaatacct
    12481 catttttatt caaacttcta tgtatataag tatgccacag ggttttctgc tgcaagtgct
    12541 ttaagtcaac agatactttc agaaggaagt actgcagtag atagatatat aaacttctta
    12601 aaaagtggag ggtcagaata cccactagaa caattaaaat ctgctggtgt agatatgacg
    12661 aaaaaagaat ctatagagga agccttaaat gtatttgctg aattagttaa taaactagaa
    12721 aaagaattat aggatgtgat aggttgatag cttcaatgaa gacttctgat aatatgagtt
    12781 gtattatgtt tatatctgcc taaagtaact ttaaaaagtt aatctaatta agaataaatc
    12841 atataaaatt aagtttttac atgtatttaa caatatttac atttacttaa ccctgctcta
    12901 atattcattt aacaaagaat ctgtattatt aaaatataga aaaatgacaa caaaaaatta
    12961 aaatataagc gggggtaagt aaaatgttta aaaagaaaat aggcgttctt ttagctagta
    13021 caatgttagt tggagcttta gcagtaggat gtagttctaa ctcaggaggt tcaggtgatt
    13081 caggagattc aagcaaagtt tctgtttcag gttcaacttc aataggtcct cttatggaaa
    13141 ctatcggaga aaagtttcaa gaaaaaaatc aaggtgttag tgtagaagta caacagattg
    13201 gttcttctgg aggtataaaa aatgctatag aaggaacatc tgaaatagga atgagttcaa
    13261 gagatttaaa agatgaagaa aaaagtgctg gattaaagga aactaaaata gcaatagatg
    13321 gtatagcatt gataactaat actgcaaact cagtaaaaaa tctgacaatg gaccaagtta
    13381 aaggtatata tacaggaaag attactaact ggaaagaagt aggaggaaat gatgcaccaa
    13441 tagtaatagt atcaagagaa gaaggttcag gaactagaga tggattccaa gaaattgtag
    13501 ggtttgattc agaagaacta actaaagatg cacaaataag tgatggttca ggaaatataa
    13561 aaactacagt tgaaggaaat gaaaatgcta taggatatat atcatttgga tatgttgatg
    13621 agaaagtaaa tagtttaaaa ataaatgatg ttgaagcaac tgatgcaaat gtaatagcta
    13681 ataaatatcc aatatcaaga ccatttatat tagttaataa agaagatggt ttgtcagaaa
    13741 aaggtaaagc tttaatagat tatatattaa gtgatgaagg acaagcactt gtttcagaaa
    13801 aaggatttat taaagttaat caataacaag agttataata taaagtaaac atataatacc
    13861 ctgtgagata agctcataaa aatgatgctt taacttgcag ggtattgtct attattgaat
    13921 gtagaaatat aaatatcttt agataaaata ggtattttag tatcttatct ctaagaatat
    13981 ggaaatattg acaaaataat attacaatgt tagaataaaa aagaaattta tgaaaatata
    14041 taaaagattt ttaataaaaa tattttagaa actgagaagt atatcttatt attgggcatc
    14101 tagagatata tggagttagt ggtgcaaccg gctatgaata taatttttat attgcatagt
    14161 ctttttttgt tttaaaatta acaaatatgt tgcaaaattt gaaaataaga gtattagtcg
    14221 ttaagatttt tattgatagg taaaattttg gcttttaaag tagccatttg ttggaaaagg
    14281 gaaatttttt taaaagaata atagtattat aataagaaaa taaagttttt ataaacattg
    14341 agatgcagaa tataaacctt ttgtaacaat atatttacca aaataataca atttatttta
    14401 tattataacc atataaatca tataaatcaa tactcaaact agccaataga caagtttcta
    14461 gaaaaataat aaatttatac gtgaaaatga ctttaagctc cattctccaa caatcggaga
    14521 ctttaattag tatttaataa tgaatcttaa tgtttaatac aatattcaag aattattcaa
    14581 aaatacttaa gtattatagt ctagtttgta aagatattat aaaataataa taccagttat
    14641 atatgaaaat aaaacattat aatttgtaat aactataaaa cttggaatta taattaaaat
    14701 acctttgaat ggagtggtgt aatgtataat ttactggttg tagatgatga tgttgatatt
    14761 ttaaacataa atcaaattta tttttctaat ataggtttta atgtatatac atcagagact
    14821 gctaaagatg ctatggatat agtagagagt atagttttag actgtataat tttggatatt
    14881 tcattgccag atatagatgg atataaaatg tgcaatgata taaaagaaaa ggttaacata
    14941 cctataatat ttttatctaa ttatgagcat gaagaagaaa aagttcgggg atttttagct
    15001 gggggggatg attatataac aaaaccttat agtttaaaag aacttgaact tagaatatat
    15061 gctcgtatga ggcagtacaa aaatattaca tcagttccta atgtgttaaa gttttcagcg
    15121 ttagtaataa atgtaaattc aagaaaagta acttttgatg gagaaagtat agatttaact
    15181 actatggaat ttgaaatatt attgtttcta gctgaaaaca aagaacaagt attttcgaag
    15241 atagagatat ataaccaagt ttggaaaatg cctgatattg gagatcaaca tacagtgcag
    15301 gttcatattg cacagatgag aaaaaaaatt aattctttaa gcagggagca tcaatacatt
    15361 caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg taattaataa
    15421 atagttcttg ttttatttaa tactactatg aaagagatgt ggttgataca atgaaaaagt
    15481 ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca ataacaggat
    15541 taaatcttct gtataaatat gataataaat atacatataa gtctattaga gcaagtaatg
    15601 gaattttaac tatagataat gatactttca ctaaaggtaa acttgtcttt ttgatagatg
    15661 actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag caagatataa
    15721 aaccagaata tgtttttata ggtcaatatc cagatttttc tatgagaaag gggactcagt
    15781 caccatatgg gaatgctact tatcgtatga gaataaaaaa tgaaggcaag gataagctac
    15841 taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat ggagaaatgg
    15901 tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa aattcagtag
    15961 taagttttat tgcaaagaaa aatacagaaa ttataatcaa tgtatcgaat ttttcacatt
    16021 attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata agtaatatga
    16081 tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca atagctatat
    16141 tttcattgtc tgtatggttt ctttcaaaca aaagtaaaat ttacttatat tttggatgta
    16201 tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta ggactgcctt
    16261 tggtaagctt tacatatgcg gttgaagatt tgtcatattt tatggtagtt ttatgtatta
    16321 tttgtataaa tggaagtata tccaaaatag aagaaaataa agtgtacaga tttttaattt
    16381 taccattagg aattacaatg agtatcatat ctatagtgat accaattatt cttcttccat
    16441 atgatatgta ctttgtcaac atatatggga agttaataga catatataaa tatattgtat
    16501 ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc tctgagcata
    16561 taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata ttatttgatg
    16621 cagttacgag taatagattt gagcctatat ttacagggtg gcaaacagaa tattgtgggt
    16681 ttgtaattgt tattttattt tctgttatga tgataaacag gaatagaata ataataaaag
    16741 agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact aatgaactta
    16801 caacattgtt aaatgaacgt aaaagattct tggcagatgt agcacatgat ttaaaggcac
    16861 ctgtttcggc tatacaagca tttatagatt tgataaaggt tggtaatatt catgtagatg
    16921 aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta caaaatagag
    16981 tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt gaaaaaatat
    17041 gtctgaataa ttttattaaa gagatatatg aaaataattt gccagataca caagcatgtg
    17101 gtgtaaactt tgaaacttac gtattggaga aaaaaatata tgcaaagata aataaagaga
    17161 tgcttacaag agcatttgag aatttaattt ataatgcttt gacctttact ccatttgatg
    17221 gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa atttctgata
    17281 atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc tttacagaaa
    17341 gagacaataa tgagccaaaa gggcaagggt tagggctata tattgtcaaa tccattataa
    17401 gagagcatgg tggagaaatc tttgtagatt cagaactagg aaaaggaact gtttttacaa
    17461 taaaattaag tctatatttt ttataataat agcttattta atataaaaga ataatgatat
    17521 ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa ggataattgc
    17581 aagaagctaa aaggatttct ggaggaaaaa ggaataagta tagatttagc atataattgt
    17641 gaagaagcta ttggaaaaat atttagcaat aaatatgatt taatattttt agaaataatt
    17701 ctaagtgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac tacttgtcca
    17761 attgtttata tgacttatat aaatgaagac caaagcattt taaatgcttt aaattctggt
    17821 ggagacgatt acttaataaa gcctctaaat ttagaaatat tatacgcaaa agtaaaagct
    17881 attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa attagaggaa
    17941 tataatagaa ctagtggagt aataaagtta gaagataaaa taataaaatt gactccaaca
    18001 gaaaataagt tgttaaactt ttttatagag aatcctgaaa agactttgac tactaaagag
    18061 atatatgaac atgtatggat gaatgaatac ttagaggata actatagtgt ggtagttgca
    18121 gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa aattataaca
    18181 ataagaggag caggatatta ttttaataaa gaataataaa tatattaata tcattaataa
    18241 ttgttataaa tgtgaaatac taacaatatc taaactaaat tattataaaa tagctgactg
    18301 taatttaatt gataaagcct attcttctag actttgccag ttaaattaca gtcagtttta
    18361 ttatataaaa aaatgcgtaa tggaactatt attttataga ttatatttga aaagatagat
    18421 aaattgtata tctaaatcta tatattattt ttttaccttt aatatatatt aaataataaa
    18481 atagttaaat aataagatta agaatttctt aataaatcca gaagatgctt tcgattatat
    18541 aatattttat atttttatat tattaattat atatgttgca attgctgcac ctactttttc
    18601 tggtgagtat cagacacaat cagatagcat ccttcgttgt acgaaacatg gacatatttg
    18661 tctagcgttt actaaaatat tagctctatt ttctatattt ataataatgt ttgttatatg
    18721 tatttctatc tatttggcaa tttctgattt agcttttggt actgaatgtt tgaaaacctc
    18781 atttcaaatg ttgttttctg tcattagtct agtaaatata aatttactac aagcacagat
    18841 tcttatagct attggtggtc taatttcaat acttgcaatg gttagtttaa cattattttt
    18901 atctgcaaaa tgtaaggatt ctcttacttc tatgctgatt gctttttcta tttgcttaat
    18961 tcctatggga ataggtgtta gttggattgg atacctatta ccgccagggg gaattggttt
    19021 taagattagt ttattatatc aaatgacatc atttaatttc ttacacttag gaggtatgag
    19081 tttttggaca ccacacatta tactgttttt ctcagtgata gaaataccta tttttatatt
    19141 tttggctatt catacctatt gcaaacatca agtatcgtaa caatttgatg gaaataatag
    19201 tgatataaac tagaggatac aataattata tatgtagtat aaaagttaaa tttagttaac
    19261 aaatcttaat agcagatata ggtaataaat tatacataaa ctgtattatt atctatatct
    19321 gctattttaa tatagagaaa caacagtata ttgtaaagta aatgtcaaat atagttttaa
    19381 aagtaaaatt aatgttaaaa agtaaatata attttacact tgcttaactt aatcctaata
    19441 tagatttaac ttaaaaaaag tagaataaaa gtacaggaaa tttgatgaag acgaattata
    19501 aaaaattaaa ttttgaatac agaacgaaaa tcgataagta tattttaatg ggagggtatt
    19561 atgatagtaa aatctagatt agtaggttta gaaaaaaatg acaataatgg caataagaca
    19621 aaatacgtaa ttgaaaaagt agcaaaaaat atttttctac ttagtgcttt agtagcagtt
    19681 gcaagtttac ttttgataat aggatttgta ttttataaag gattaagacc atttatattt
    19741 gaaggatatt catttataga ctttttaact ggtgcagatt gggttccttc tgccaataaa
    19801 tttggaatat catctatgat agtagcatca atatttgcaa cacttggagc acttgttata
    19861 ggagtacctg ttggtatatt aacctctgta tttatagcag aagtagcacc taaaagatta
    19921 gcaaaaataa tgtcaccagc agttgaactt ttagcaggta taccttcagt attatatggt
    19981 gtatttggtc ttgcagtgat agttccaact atacaaagta tatttaatct tccaaaaggt
    20041 caaagtttgt tagcaatagt aatagtatta gcagtaatga tgttaccaac aataatatct
    20101 gtatcagaaa cagcaataag agcagtacca aaagcataca aagaaggttc attagcactt
    20161 ggtgcatcaa aaatagaaac aatattcaaa gttgtattac ctgctgcaaa atctggagta
    20221 ttagccgcag tagtgttagg agtaggaaga gctttaggtg aaacaatggc agtaatactt
    20281 gttgcaggca actcaccagt tatgccaact gcaataacag atagtgtaag accacttaca
    20341 actaatatag cacttgaaat gggatacgca tttggtacac atcaagaaat gctatttgca
    20401 actggagtag tattgtttac atttatatta attttaaact tagttttaaa taaactttca
    20461 aataaggcgg taaattaaga tgagaaagtt caaagagaat ctattgaagt cattagtata
    20521 tctatcagca ctatttacaa tagtatcatt agtagttata gtgggattta tatttataaa
    20581 gggaattggc aacatgaatt ttaatttctt atttagcaat tattcagcat caggtgatgg
    20641 tggtatactt ccaatgataa ttacaacatt atatacagta gtagtttcta tagttgtagc
    20701 aactcctata ggaatattgg ctgctatata tttacaagaa tatgctaaaa aaggaaaagc
    20761 agttacagct ataagatttg caactgaaag tttatcaggg ataccatcta tagtatatgg
    20821 attatttgga ggaattttct ttgtagttac attaaaaatg ggatattcca tagttgcagg
    20881 ttcacttaca gttgcaataa taatattacc agtaataatt cgtacaacag aagaagcttt
    20941 aaaaacagtt cctcaagctt atagagaatc atcattggca ttaggagcta caaaatttca
    21001 aactttatat aaggtagtac ttccaagtgc aataccagga attttatctg gagtaatctt
    21061 atcagttggt cgtataattg gagaatcagc tgcaatatta cttacagcag gtactgtagc
    21121 caagatgcca ggtggaatat ttgatagtgc aagaacatta actgtacact catacttact
    21181 gactaaagag agtggagata tagcaacagc agccagtata ggaattgttt taatagtaat
    21241 tgtattagca ctaaacatgc tagcaagatt tgttgctaag aaattaaata aagctaatta
    21301 ttaaatttaa gaggtgtgaa taatggaatt aatcgataag ataaaaatga gtgtaaaaga
    21361 tttggattta ttttatggtg ataagcaagc attaaagaaa ataaatatgg atataaaaga
    21421 gaataaggtt actgctttaa taggtccatc tggatgcgga aaatcaactt ttataagaac
    21481 gttaaataga atgaatgact taatcgaaga tgtaacaatt aaaggaaaca tttctgttga
    21541 tggagaggac atatatacct cagatgatgt tataaatctt cgtactaaag taggaatggt
    21601 atttcaaaag ccaaatccat ttcctatgag tatatatgat aatgtggcat atggtcctcg
    21661 tacacatgga ctaagagata agaagcaatt agataaaatt gtagaagaaa gcttaaaagg
    21721 tgcagctatt tgggatgagg ttaaagacag gcttaaatca tctgcactag gactttctgg
    21781 tggtcaacaa caacgtatat gtatagcaag agcaattgct atgagaccag aagttattct
    21841 tatggatgaa cctacatctg ctttagaccc aatttcaaca ttaaaagtag aggaacttat
    21901 agaggattta aaaaaagact acacaatagt catagttaca cataatatgc aacaagctgc
    21961 tcgtatatca gatgaaacag cttttttctt aaatggagag gttatagaat ttagcgatac
    22021 aaaaactatg tttaccactc ctgtagataa aagaacagaa gactatataa caggtagatt
    22081 tggttaaaat atataactat aaaggagtta gacaatggtc aataatagct tagatataag
    22141 tattgatact ttaaaagaac aaacagtgct tatgatggaa aaatgtgaag aagcaataga
    22201 aaagtctgtg acttgtatga tagagaagga tttagagggt gcaagaaaag tagtagaaga
    22261 tgatgaagaa ataaataaat taagagaaga aataagagat aagagtatag agctaatagt
    22321 attaaagcaa ccaatggcaa gggacttaag atttatttat tcattaggta atatatctat
    22381 agagctggaa agaataggag attatgcagc aaatatagct agagaaatgt tgaagatagg
    22441 tggagaggct tatataaaag agctaataga tattcctaag atggcaaaag aatgtaagtc
    22501 tatgatgtct cagactagag aagctttaat cttatttgat gcaagtatag cttatgatgt
    22561 tggaactaaa gatgatattg tagatggatt gtatgaacaa gtacaaattg attgtttaaa
    22621 aataatgcat gaaaactcaa ataccataga ccaaggggta aaacttctac ttataggaag
    22681 ataccttgaa agaattggag accatataac aaatgtatgt gagaagataa tttttgcaat
    22741 tgagggtaaa atggttgaga taggataaaa aactgcttta aagcagtttt tttattgtct
    22801 aaattaagaa agaattgata aaaaaatatg attaatgggt aaatttaaaa aattgtgata
    22861 tactaggaac atattaaata tgaggatgcg tattttatat aaggtgcttt ttaggaggtg
    22921 gaactttgaa acttcaaaag atgggtatga ggactataaa aacaggaatt agtgtcactt
    22981 tatgtatgat tcttggtgac tatttagtag agaatatgtt ttattctctg gtagcatgta
    23041 taatttctgt tcaagataca gtaaaaggtt ctttaaagac gggaatcaat agagtggaag
    23101 gtactatttt aggtggtata ataggattca tatttgccat cattaaagct ggagacccat
    23161 ttttatgtgg tctaggagta atgtgctcaa tatatttatg caatctgttt aaaataaagt
    23221 cagtagtagt tgcctgtgta acctttctgg ctatacatct aggtgtagga aatagtgacc
    23281 ctgtgtatta ttctttacat agggtgttag atacatctgt gggtgttttg tttggagtac
    23341 ttgttaatta ttatgttgct agaccaaatt atctaaatag tgttatagat gagtttaaaa
    23401 agatagaaga actttcaatg ttgcttattg aagataaaat tcttagaaaa gaaaatttaa
    23461 atgtagagaa atttgaagaa gaagtagaaa aattagaaga aatatattca aaacttattg
    23521 atgagttgga ttatagtttg agtgaaacta atatagaaaa aattgagaat gccttaagga
    23581 tatgtagaga aatacatttt catatgcagt ctatagagtt acttgaaaat aaactttatt
    23641 tgaaagagca tacatataaa taccttaaga aaacatataa tgtggataag ctagactgga
    23701 atatagatga agaaaaaagc cctgtattca actatcatct aatgaaaata atgattgaaa
    23761 tagagttgtt gagaaaacta aataaatcat attaataata gtagttaaat aataaataaa
    23821 aaatagtatc tttgtaaata ttaaacatat ataagtttaa tttatggagg tactattttt
    23881 tatgaatact agaaatgaca attctaaaat actagaaata tataaaatga agctttttgg
    23941 cgaacttgta aaagcagtgt ggaatgatga catagaggat attgaaaact tacctaataa
    24001 aattttaaat gaaaatttaa aggataattt aaataattat tttagtggaa aatttgataa
    24061 agatactatg gtaaatttaa ttagggtaac tatgggattg gatgtgacag aagatacaga
    24121 taaaaattta aaagagtcac tacatgaagc tgtaaattta gatgaagtca aaagaccaat
    24181 aatatctgta atatcagatg cttgcaaata ttgtgatgaa aataataagg aagatgagtc
    24241 atgtaagata agaagtaagc atattaattg taatgaggaa gatgtatgta gtgcttgtgg
    24301 tgattgtgta tcaagatgta agttgggtgc aatttcagat aaaatagaat ttataccaat
    24361 gataaaattg ttaaaagata taaagagccc tgtatatgca atagttgcac cagcttttgt
    24421 aggacagttt gggaaagatg taagccctgg taaattaaga actgcattaa aaaagatagg
    24481 atttgaagat atgatagaag ttgctttggc agcagatatg cttactgcaa aagaagcata
    24541 tgattattat gagcatatga aaaaggacga agaaggatgc tttataacta gttgttgctg
    24601 tcctatttgg gttagtttga tacaaaatag ttttcctcaa atattggaga atgtatcacc
    24661 atccgtttct cctatgattg cttgtgggag agctgtaaaa attttaaatc cagatgctaa
    24721 agttgtattc ataggtcctt gtatggcaaa aaagaaagag gcaatgttag aagatataaa
    24781 agatgcagtt gattttgtgc ttacatttaa agagttgcaa gaaatatttg atgcattaga
    24841 gttaaatcca gcaataatgg atgagagtaa tagagtagag gcgtcccttt caggtagagt
    24901 ttatgctaga acaggaggtg taagtaaagc agttaagtta tcagttagaa gaattgacaa
    24961 aaatataaaa tttgaagaaa aggcatttga aggaacaaaa gagtgcatgg acggtctaaa
    25021 gaaagttcta aataaagaaa tagaagctac atttatagaa ggaatggggt gtgtaggagg
    25081 ctgtgtagga ggtccgaagc gtattttaag tgtggaagaa ggtactaaga atgttgatga
    25141 atatagtgaa agtacgaata tggaaactcc atttgataat ttaaatgtat tacaattttt
    25201 aacttctttg ggaatcaaaa gagtagaatc tttaggagaa aaagaagaag aaaaggttaa
    25261 aaaaatattt agtagagata taaaaagtaa taagaaagag aataaatata aaaaataact
    25321 ttttaagtct taaacttatg cttttataaa agggagatat gggggatgaa aattaaagat
    25381 aataaggctg tttttcatgt atttataagg atatttctta tagctgtttt aattttaact
    25441 ggaacattat tggaggaaaa aattaataat gttccagttg aaaatataag ttcaaaaggt
    25501 gaaaatacac tggaactgct ttctcaaagt aatactttag gagaaatcat atacaaagca
    25561 tctcaagaag aaacaaaagg tccaggggct acttctgaaa aagtagcata cataacaata
    25621 gatgatggtc catcaaaata tacaaatgca ctacttgata ttttaaaaga aaatgatgtc
    25681 aaagcgacat ttttcatgct taatcagaat atgaaaaacc acaaggaaga agtaaggaga
    25741 gtcttggaag aagaaaactc aataggtttt catagtgtaa gtcatgatat acataagtta
    25801 tataaaagcc cagaagtaac agttggggaa tttaatacat gcaataatac tctacaagaa
    25861 ataactggtc agagttcaaa attaataaga ttaccatacg gaagtaaacc atatatgcca
    25921 gaaggttcat ataataaact tatggcaaat gattatttaa tttgggactg gaatttggat
    25981 acacaggatt ggaagtcttc tacaagtcag atagtaagta atatattata ttatggaaga
    26041 aaaagagatg aattagtagt attaattcat gagaaagagc aaagtttaaa tgctttaaat
    26101 aatattataa gaatcttaaa agagagagga tatacaatat tgccaattac agaaaatata
    26161 acacctaaaa atttctggca agaaaactta taataaattt aaatatagta aaagataaag
    26221 taaattattt ataaaataaa acatataata taaaaaatac gaataagagg tatactgtaa
    26281 ggataatata aaattaatga gaaagcatta aaattaaaat aaaataatct tgcaattatt
    26341 gacattataa gacagaataa ctgtaaaaac atattttaaa atataacaac tatataaaag
    26401 agaatagaca taattaagaa aattcagaaa aaataaaata aaaataattg acaaagagaa
    26461 taatatttgt atataataat atgtaatatt aaagactgag aagaagagga gtaagtaaat
    26521 actactaaaa gagaggaaaa ttcactggct gtaagatttt ctaagtataa gatttactga
    26581 atgtagcttt ggagtttcta aactgaacta taagtaagtt tagacggtta gaaccgttaa
    26641 attctttgag agtcaaagtt gataaaataa cattaaccaa taatttaatg atatgttaat
    26701 gtattttaag ctttggaatt aaggtggtaa cgcgagcttt tcgtcctttt taaagaggat
    26761 gaagagctct tttttatttc taaagatatt taaaaaattt atttataaaa tacaggaggc
    26821 aggacaatgg aaaatacgaa tttatcaaaa acttataacc caaaagattt tgaggctagg
    26881 ctatataaaa aatggatgga tgaagggtat tttaaatcta aaccaaatcc agataaaaaa
    26941 ccatttacaa taatgatgcc accaccaaat ataacagggc aattgcatat gggacacgct
    27001 cttgaccata cacttcaaga tatattaatc agatggaaac gtatggatgg atatgaagct
    27061 ttttggcttc caggaactga ccatgcttct atagcaacag aagttaaagt tgttgaaaga
    27121 ataaaaaaac aagaaggcaa gacaaagtat gaaataggta gagaagaatt tttaaagaga
    27181 gcctgggaat ggaaagatga atttggagga aaaatatcta atcagcttaa acaactaggt
    27241 gattcttgtg attgggataa agaaagattt actatggatg aagggtgtaa tgaagcagtt
    27301 atagaatttt ttgtaagcct atatgaaaaa ggtcacatat acagaggaaa tagaataata
    27361 aactggtgcc cagattgcaa aactacttta tcagatgcag aagttgaaca tgaagaacac
    27421 gacggaaact tttatcatat aaagtaccca ctaaaagata gtgaagactt tttagaaata
    27481 gctacaacta gacctgagac aatgatagga gatactggta tagcagtaaa tccagaagat
    27541 gatagatata aacatttaat aggaaaaaca gcaatacttc cattagtagg aagagaactt
    27601 ccaatagttg cagatagtta tgttgattta gagtttggaa ctggtgcagt taagatgact
    27661 ccagcacatg accctaatga ttttgaagta ggattaagac ataatcttga gcagttaaat
    27721 actatgaatg aagatggaac tatgaatgaa gtttgtggaa aatatgaagg tatggataga
    27781 tttgagtgta gaaaagctat cgtagcagac ttaaaagaac aaggttacct aattaagata
    27841 aaagagcata atcataatgt aggaacttgt tatagatgcc atacagtagt tgagcctaga
    27901 ttatcagagc aatggtttgt taagatggaa gaacttgcaa aaccagctat agatattctt
    27961 aaaaaaggag aattagaatt tgttccagat aaatttgata aaacttattt acaatggcta
    28021 gaaaatataa gagattggtg tatatcaaga caattatggt ggggtcatca aataccagct
    28081 tattattgtc aagagtgtgg agaaatagta gttgctagaa aaatgccaga taagtgtcct
    28141 aaatgtggaa gcactcattt taaacaagat gaagatgcct tagatacttg gttcagttct
    28201 gcattatggc ctttctctac tctaggatgg ccaaataaga ctgaagcttt agattattat
    28261 tatccaacaa gtgtacttgt tacaggatac gatataatat tcttctgggt agttagaatg
    28321 gcatttgcag gtatgttctg tatgaatgaa aagccatttg accatgtttt ggttcatgga
    28381 ttagtaagag attctcaagg tagaaaaatg agtaaatctt taggaaatgg tatcgaccca
    28441 ttggagataa tcgagcaata tggagctgat gccctaagat ttacattaac aactggaaat
    28501 tccccaggaa atgatatgag attctatatg gaaagagtag aatttgctag aaactttgca
    28561 aataagttgt ggaatgcatc aagatttgta tttatgaata ttgatgaaga tataattaaa
    28621 aacatgacta gagaaagtgt taaagaggac ttaactctag ctgataaatg gataatatca
    28681 agagcaaata atattgtaaa agaagcaact aataacatgg ataagtttga tttaggaata
    28741 gcacttcaaa agatatacga ttttacttgg tcagaatact gtgactggta tattgaaatg
    28801 gttaaaccta gattatatgg agaagatgca aatgctaaat ctgcagcatt atatacatta
    28861 acttatgttc ttgaaaaaat attaaaatta ttacatccat acatgccatt tataacagag
    28921 gaaatatata ctcatcttcc tactgttgaa ggatgtataa tagtatctga atggccaaaa
    28981 tataatgaag aagataacat ggctgaagaa gaagatatga tgaacttatt gatggaaggt
    29041 ataagaagta taagaaatgt gagagcagaa atgaatgtac caccttctaa gaaagctaaa
    29101 ttgataataa tcccaagtga agaaaaaata gaagctattg agcttggtaa agactatttt
    29161 ataactttag catctgcttc aaatgtagag atagcaaaag ataaatctaa tgttccagaa
    29221 gatgcagttg gagtagttat tgatggtgtt gaaatattta tacctcttaa tgaattagtt
    29281 gattttgaaa aagaaattga gagattatct aaagaaaaga aaaagttaga aggcgaaata
    29341 aagagagtta atggaaagct tgcaaatcaa ggtttcttag caaaagctcc tgaaagttta
    29401 attgaagaag aaaaagcaaa aaaagaaaaa tttgaagaga tgattaaatc tgttgaggaa
    29461 agattaacaa atttagaatc taaaataaaa taaatataag aattagtaaa aacatacaaa
    29521 aagtatatat tctatacttt ttgtatgttt ttctttatat atatacaaat atgatgttat
    29581 aattctttac agatgtgtta tatttttatt ttatgttgtg aatatatgaa ttttatgtct
    29641 taaaatttat aagcaataaa aatttgatat attatgatgt ttaatatagg gtaataaata
    29701 catattatat ttattttact atattttttt acataatata tctagaaaag tataggaatt
    29761 tatcgtaatt taagtttaaa tattaaagag aatttctata agtagtttaa tcgacaattt
    29821 aaatttataa agaaatttaa atttgaaagc tagtgagtac agtttggaaa ttgaaataaa
    29881 gtaaactaaa tgatatttta gatttggagg tgatattatg ttcagggtag ttatatgtga
    29941 tgacgaaaaa atacaaagaa gcatactaaa agagtttaca gaaaaacttt tgtctgaaag
    30001 atgtctaaat tatcaaatac tggaattttc ctgtggagaa gatttaatat ccaaataccc
    30061 agaaaaaatt gatattatat ttttagatat ccaaatgaaa gatatcaatg gaattgaggt
    30121 ggctaaaaaa ataagaaagt ttgatgaaaa agtagaaatt atatttacaa cggctttttc
    30181 agagtatgcc ccccaaggtt atgaggttcg tgcttataga tatttagtaa agcctataga
    30241 gtatagtaac tttgcaatgg gtgtaaatct ttgtattgat aaccttcaaa gaaagaagga
    30301 gcgttatata gttttaaata gtaaaaaagg atttaataga atactgatag attctatttt
    30361 atatgttgaa actgtaaaga gagatttagt cgtacataca ataggtagag attataaagc
    30421 taatatgagc atgaaacaag cagaaaaatt actgtgtgaa aatggctttt ttagatgtca
    30481 tacaagtttt attgttaatt taagaagaat agaagatctt agggataata tgattactat
    30541 taatgaacaa tttataccta taagtaagta tagacttaaa gatttaaaag tagcattaac
    30601 aagcttgtta tgtgatataa tgtattaatt ttaaaaaggt aattgaaaat atcgtaaaaa
    30661 agatttaatg tcatcacagg gctattgatt gaaactgtct taatatataa aatgttattt
    30721 atattaagac agttttatta tgcaaaatag cagtttatag atttttaata tggtttaaca
    30781 tgtatatgta gaggttccat tatagtagca tgattattaa ttagtagctt gattatcaat
    30841 atactattat tgatttttat atgcattata tgtattttta gaatatgatt acctttttaa
    30901 aataatgatt atttataaaa ctctatagat atttgtttca tttagctacg catactttaa
    30961 ttaattatat taatatttaa tggagtacaa tataaatatt aaagcgacat cttatagttt
    31021 attgaaacta tagtaatgaa ttaataaata gtttaattct atgaaaagat ttccttttat
    31081 gcaatttatt tattgaaata tgatataata tataaaggtg taagtattag ttgttaaaat
    31141 aatatttata ttagttttta tacatacttg gtataagttt ttcatatatt gattaaaatt
    31201 gatgttgatt tattattttt agtatttttt caccttttga ttcatacttt gtagaatggt
    31261 gtattttcta aaactgatta taagacaagt tcattcaaat tagcattttt atatcatata
    31321 aataattgtt ccccctaaat aagatttaga tgtatagtat taaaatcaaa aagtataaaa
    31381 taaaattgat gcttaatcat agataaatat taataaaata tacaagggga ttgtctaata
    31441 aaaagataat ctcctttttt acaaataatt ctaaattgtg atataaatct aaaaatttta
    31501 tcttaacatt taaccattta atgataataa ttgatataat aaatataaat taaatatatg
    31561 gtgtacttat tttatgtttt tagcaagaaa tatagcattt aaaagataaa ttgtgcaact
    31621 taaatcaaag tttaagatga actattaaca tagatatatt aaaaactttt gtaatggaga
    31681 atatatgtga tatgaataat aaagttaagg ttgcagtatt agatacagga atagacaaag
    31741 aacatgatta cttaaaagat aatttagttg gaggaattgc ttttgaatgt atgcatgatt
    31801 atatctttat atcagataaa tttgatgatg aagatggtca tggaactgct tgtgcatcaa
    31861 taataaagaa agagtatgaa gatgtagagt tatttgtaat aaaaattttg agaaaagatg
    31921 gtattacaaa tataaaagtt cttgaagaag cattaagata ccttttagac actaacataa
    31981 gattaattaa tttaagttta tcagtcatag gagtagaaag tgttaagggc ttatttgaag
    32041 tttgctatga attgtttaga aaaggaaaaa taatagtatg ttcactcgct aatgattttg
    32101 acttaagtta tccagctatg tttaacaatg ttataggtgt aagaggattt actttagatg
    32161 gagatgattc attttggtac aacaaaaaat atgatgttca atgtgttatg gatagcaatt
    32221 catatataag ttgtgatata aataattcct atagattacc accaaaatgt aatagttatt
    32281 tatcagcaaa gcttactggt aaaatagcta agatattatc agaaaaacca ggcataacaa
    32341 tatctgattt aaatgataag cttgaatcat tagcaactag aaatcattgg gatagttgtg
    32401 attttgatga gtgtagtaga attgtaaact ttaaattgga tttgtatgac aaagaaaatg
    32461 ctctttttat gaaagttgct gacgttgtta gggattgctt agatattgaa gagaataatg
    32521 aaaaactctt taagggtagc ctttttaata aggagatagg cttggtttat gataattgtt
    32581 ttaatctgtt gaaaaagcta gagcatagat ttgacataaa gtttaattat atggacatct
    32641 caaaatatga cttagtttca atatatacac tgactgaatt agtggaaaga tataaaaact
    32701 tataaataaa gatttgtagc taaatttaat gtagaaggta ttaaattata tgtattcttt
    32761 gtcggtagat taaaagtaaa aaatatacta taattagata gcataagaga aaatgccaat
    32821 acagggggag ttagataatg aaatatgaag aagcattaga gtacatatca caaactaata
    32881 aattcggtat aagattagga ttagaaaata tcggaaagtt attagaatta ttaggaaatc
    32941 cacaagaaac tttgaatata atacatgtag ctggaactaa tggaaaaggt tctgtgtgtt
    33001 cttttgtttc taatatacta agagagtgtg gatataaagt tggtttatat acatctccat
    33061 atttagaaac ttttactgag cgtataagag taaatggaca aaacatacca caggatgatg
    33121 ttgctagaat aattgagtta ataaaagaaa aaatagagat tatggtaaaa gaaggctatg
    33181 catatccgac agaatttgaa gtggttactg caatggcatt ttattactat tcagaacaaa
    33241 aggtagactt tgtggcatta gaagttggtt taggtggcag atatgatgct acaaatataa
    33301 taacaaaatc acttgtaagt gtgatagtat ctataagttt ggaccataca ggtatacttg
    33361 gagatacaat agaaaaaata gcgtacgaaa aggctggaat aataaaggaa aatggagtag
    33421 tactagtata tgaccagact gatgaagcaa aggatgttat aaagtcagtt tgtaaagaga
    33481 aaaaagctaa atatatagaa gttgattttg atgatataaa cataaaaaaa tcagatataa
    33541 attctcaaat atacgattgt actgtaatga aagaaactta tagagacctt gaaataaaat
    33601 tgataggcga acatcaaata aacaattcta tcttggcaat tagtgtaata aaatatctaa
    33661 aagacataaa taaattagca aatataaatg aagaatctat aagaaaagga cttataaata
    33721 ctaaatggcc aggaagaata gaaaagataa aggaaaatcc aatttttata atagatggtg
    33781 cacataatga agatggagca aaatctttgg caaaagcact tgataagaat tttaaaggta
    33841 gaaaattaac cttattaata ggtatgttag aagataaaga tattgatagt gttttagaga
    33901 tattgttgtc acattttaat aaggtaataa caacaacacc aaataaccca agggccataa
    33961 attcagatat attaagagaa aaagtattaa aatatgtaga tgatgtaaca tcaaagcatg
    34021 agatagagga tgcagtaaat tatacattag aaacatcaag tgaggatgat attataataa
    34081 gtgcaggttc attatatatg attggtacag tgagaacttt agtaaagaaa ttataatttt
    34141 ataaaataag tatacaaata aaaatataaa aaagagttgt ctaaaaaatg gacaactctt
    34201 tttatataaa ataagttttt aataatttta ctgatgttta tataagtaat tatatagatt
    34261 gacgtatagc tttagataat tggtctgggc aagaagtacc ttttccacca cagtcaatac
    34321 catttaattt atcagcaact tcaagagcat tttggccaat tattaagctt ctaagtcctg
    34381 ataaattacc attacatcct cctataaact cagcatcaac aatcacatta ttttcatcaa
    34441 cttcaaaaat catttctcta caacatacac cacttggatt aaatgttact ttcattaaaa
    34501 agacctccat taaatattat ttcttttttt aacattaata ataataccaa atatatgcgt
    34561 aataatgcaa ctataaagca taatacaagc taatgaaata atatattatt gtagtatatg
    34621 tattgtagag aggaggggtt atatgaaaat ctatatttct aactacttat caaagagtat
    34681 tagcatagtt gattattcta cacttgaact agaaaaagaa atagtattag aagataatat
    34741 atatccacac catttttgca tagaaaaaga aaaaaattta atatacatac ctagttcaag
    34801 taatgggata ctctatgtct tagatttaag taatgataaa ataattgata ctgtctctat
    34861 aggaggaagt cttagtcaag ttgtacttag cgataatgaa ttgtttgtgg caaatgaaga
    34921 ttctaatagt atatatgtac tagataaaaa cacattaaat ccaataggaa ttattggagt
    34981 tgataatatg ccacatggat ttgactttga tagagaaagc aaaaagttat atgtaccgtg
    35041 tataaactcg atagtatgta tagatacaat taataaaaat atacaaaaga aaataaatat
    35101 ggactttaga gcttggcata tagaacttga taaacaaaag aaagaaatgt atatatcaac
    35161 acttgatgga aagcttataa taatagatga agtaagcatg gatataaaaa aggtattata
    35221 tgaattttta ttaccagtag aaataagatt taattatagt ggcaaaaaag tttatgttgc
    35281 tgatttgggt tataataatg taagaatttt agattataca acgagtagat acattggaaa
    35341 tattgaaata aatgggattc cccaaggatt agaaatatct aaagatgaaa agttactatt
    35401 tgtatcagat acacaagaaa attcagtaaa agtttatgaa actgcaaata acaaattaat
    35461 aaaagaaatc aaggtaggaa aagagcctac aactataatt tgtttgtagg ctttaatgta
    35521 tgtctcttat aagtaaatcg ataacttcgg catacatata agatgcatta tttttccagt
    35581 tattgcaaat aagttttgct tgtttctctg atgaaacatt tagatttaaa tctattaagt
    35641 tagactgatt ttctatgact ctaaggttga caataaattc attatcactt tgttttacaa
    35701 aactagactt tacttgagta tctgctagta gattttcttt gttagaatct atatacttgt
    35761 ctattttttc agtaacacta gtaggtattc gattaaagaa gtattctaga ctttctacgc
    35821 ctctttgagt aagagcataa tattctctgt cagagtcttt atatgtagtc aaaaacttag
    35881 attccataag ctgagataaa agctgttgta atgaaaaata attcatcatc tcagtctcta
    35941 atactacttg agttatttga gaattagtta aatccatttt aattttttct aatatatata
    36001 aaattaaaag tttgtgatag gctaattctt cagacgagtt ttcaaacata aatatcatcc
    36061 tccgtcaaac tatttctata tataatatat taaactaatt tgtacaaaat taaaagaaca
    36121 atttgtattg tattattaat ctttaataat tcatataaaa acaattttat aaataaatat
    36181 agaaaaacag ggctgctaat tagcagccct gttgataccc aggtgtcaaa atttactatt
    36241 tattttccag ccatttgtct ttcagccatt tcaactaatt tcttagtcat atatccacca
    36301 acatatccat tttctctagc tgttaagtta cctttgtcta tgttttcata gttagataaa
    36361 cctatttcgt tagctatttc taatttcatt tggtttaaag cagcttttgc ttctggaact
    36421 actgttctgt ttgaatttga catagtaaat ttcctcctca aataattagt ttatgatgtc
    36481 taacaacact tttatttatg tgatgttaat actaatttct ccaaaataaa aataatatat
    36541 acagaaaaat aaaggtaaaa atgtaaaaaa tataaaaaaa ttaaataaat gagtatttta
    36601 gagagtttaa ttaggtcaat ataggtttta tttttttagt tattgtctta taaattaaat
    36661 attacagtac ttttttgagc tgaaaaaaaa taaattttaa atatagaaga aattatttca
    36721 aagggggaat agtatgaaaa gagaagttaa aaggactaaa gctttgatat atagtgtttt
    36781 atttttttca ttattattag tgttaatatt tgtttttgtt tatggaataa aatacatatg
    36841 ttctaaatct gacaattcaa aaatgcctat atataaagtt gatacaaatg agaaaaaaat
    36901 agctttgagt tttgatgtag catggggaac tgataatatg gatgatattt taaaaatttt
    36961 agataaacat aatgtaaaag ctaccttctt tttagttggt agttgggtgg atgataatga
    37021 agaaattgta aaagctatag atgaaaaagg acatgaaatt ggaaatcatt caaatactca
    37081 tgccaatttg aaggaaatat caaaagaaga cataacaaaa gagatagaaa ctacatcaga
    37141 aaaaatatat aatataacag gaaaaaggac taatttattt agacctcctt ttggggacgt
    37201 aaacaataaa gctatggaca tttgtagtga tttaggttat aaagtaatta agtgggatgt
    37261 agattctata gactggaagg agcttggacc aaatcatgta attgaaaaag taataaaaga
    37321 atctcaacct ggttcaatag ttttattcca tgctaatata aatgatgtag ataactattt
    37381 ggatactata ataagtcgac taaaaaaaga tggatacagt ctagtcaaaa tatctgattt
    37441 gttgtataaa gataattatg tagttgattc caatggagtg caaaaaacta agaattaata
    37501 agtaataaat gtatatttta agtaaagttg tgataaatta tatagtatat gttagaaaag
    37561 tgtcgataaa aagacggtgt ctattttttg acacttttta tacatgtatg caatatcaat
    37621 aattatagat taaattgatt aaaaaagtgt ctaataattg actttttttt gatgggttta
    37681 aaaatttaga agaattaatg aatgctgtaa gacagtattt ccaaagggta taagtttgtt
    37741 taaaagttgg catagaaatt gctttgttaa taagcgatat gttctataga aataaacaat
    37801 atgttaagac cttataatag aaaaatagca ttaacattat ttgaacagct tataaaaaaa
    37861 ttaatatact taagggggcg tactagttga acaaactata ttctatttta ttaaaacaac
    37921 acgttggtgg tccagataag ccagtagtaa gtgttggaga tgtagtaaaa aaaggaactc
    37981 taatcgcaga accaactgga ttaggggcaa atatttatgc cagtgttagt ggaaaaataa
    38041 gtgaaataaa tgaccaagcg atagtaattg aagctgatga agtacaagaa gatacttttg
    38101 aaccattaaa aggagaaggt atacttgact taattaaaga agctggagta gtaggaatgg
    38161 gtggagcagg attccctact catgtaaaat taaacataga tttaaatggt ggaacaatat
    38221 tagcaaatgc agctgaatgt gaacctttat tagctcataa tataaaagaa atagaagaaa
    38281 gaccagaaat agtttatcaa ggtataaaat atgctatgga agttactaat gctggaaaag
    38341 gtatgctagc aataaaaagt aagcatccaa aagcaataga agctttcaaa aaagtaataa
    38401 agccaggaga caacatagaa gttgcagaac tagttgatat gtacccaatg ggagaagaga
    38461 gagcaatagt aagagacgtt ctaggaaaat tacttgagcc aactcaatta ccttcagagg
    38521 ctaatgcagt agtaataaac gtagaaacac taactagaat agtagaggct gttgagcaaa
    38581 aaagaccagt tatatctaaa aatataactg tagttggtca attaaacagt ggaaaagaat
    38641 ctatagtgtt tgaagatgtg ccaattggaa caactgtcgg agaattaatt gaaagagctg
    38701 gtggaataaa aggtgaatat ggtgaaataa tcctaggagg acctttcact ggtaaagcta
    38761 ctactttaga tgctccaata actaaaacta gtggtggtat aatagttact atgccatttg
    38821 ttaatgaaaa gagaaaaatg ggtcttttag tttgtgcatg tggacctaat gaagaaagaa
    38881 tgagagatat agcaactaaa atgggagtta ctgatatagt atcagttcaa aaatgtaaac
    38941 aagctcaaga aattaaaggt gcattaaaat gtgaaaatcc aggacactgt ccaggacaag
    39001 ctcaaaaatg tattgaattt aagaaagctg gagcagaagt tatattaata ggaaactgta
    39061 ctgactgtag taacacagta atgggttctg caccaaaatt aaaattaggt gtatatcata
    39121 ttactgacca tgtaatgaga acagttaatc acccattaat aagaagaata aaaggtgacg
    39181 taagattaaa aataaaataa tagataaata gaagttagac atctttagaa gtaaaactta
    39241 aaagttactt ctaaggatgt tttttaatgt attttgaggg caatatatat attgtaaaat
    39301 aaatggaaaa aatagacaaa atatgctaga tattgtataa tgataataat agctattaca
    39361 attaatattg gacaaaaata atgatactca agtatgtggt ttgtattaat atgcatatta
    39421 tattaagtca actatccgat agagtaaaag gtttttgtga tatttgaaga tactctatag
    39481 tatctttttt attataaaaa ctaatttttg tcttttatta gataagtatc taggatacta
    39541 atttatattt tattgagttg ttaaaaaagt gcacttaaaa agttaaaaaa gaaaaattaa
    39601 aaaacctatt tatagaaact gtgaagtata tcttaaacct gggcacttaa aagatatatg
    39661 gagttagtag tgcaacctgc tataaatata aataggagta acttttaatt gtcaaaaata
    39721 tataaaataa atacataaat aagtaattaa tagaagatag atataaatat atttttgaaa
    39781 tgctccctgc attcataacg agtgtagagt ggcagatatc tgcccaaaac tcctttaatt
    39841 gctggaagtt cctaaagcta actaaaccac aacataatca tgaaataagg ataagtgtga
    39901 tagagtgtgc atttaataag cacttgaggt tacgaaagta gaaaaaatta gttagatagc
    39961 ataaggttaa atcctaagtg ccttgaaaat ggataatcag caggtaagct tcgaaaagaa
    40021 gaaacttcaa cgactagaga gaaatctcgt acctacaagt gtggggaaat ggggagtacc
    40081 taatttatgg ttaggtaatg atatagtctg tgcttaatag aaatattaag aagttcatag
    40141 gagaactggt taggagtaac gaccctaatt gaacacacta aagatgtatt attgaataag
    40201 attcatataa tatttaataa ttttaattat attaagtgaa tacaatatat gtttttagta
    40261 tcaggagaat tttgaaaaca aaaattaaaa aatcaagtat aatcagttta gtaattgctt
    40321 ttagtatggt gtttactgca tttacaccaa tagtatctta tgctgacgaa gtgactagca
    40381 atgatacaat acttaatgga gaagaacaat caaatggtca gacaccagat gtagagaaac
    40441 catcagacgg tcaggtacca gatggggaga aaccatcaga cagtcaagta ccagatgggg
    40501 agaaaccatc agacggtcag gtaccagatg gggagaaacc atcagatggt cagataccag
    40561 atggggagaa accatcagat ggtcagatac cagatggaga gaaaccatca gatggtcaga
    40621 taccagatgg agagaaacca tcagatggtc agataccaga tggggagaaa ccatcagatg
    40681 gtcagatgcc agatggagag aagacatcag atagtcagac gccagatgta gagaaaccat
    40741 cagatggtca gatgccagat ggggagaaac cattagatga gcaaactcca gaagaagaaa
    40801 aaccattgga agaagaaata gttatagagg aaatgagttt aaaacaagat attgataaaa
    40861 ttcttgatat gactttatct caaataaata aaatagtata taacttttgg gaagatgaag
    40921 aagatgtaaa ggcagatgaa caatcagaaa ttaaccaagt ttttacttca gaagactcat
    40981 ttattagctt atggtatgac aaaaaagcaa aagtaaaaaa ttcttgttta ctaaaagaaa
    41041 tagatggttc agatagacct tatcatgatt taagatttga tgatattaca aagactttaa
    41101 cttttgacta tgtaataaag ggtcttgtag gagcaagctc aaaagacgac aaatatgtaa
    41161 tagaaggtga agatggagag caaactgcat tttgttacaa taatcattta agaccaccaa
    41221 gtagtaatgg aaagagtcca tatttaccag cagaagattt taatggtcaa gaaaaccaaa
    41281 atgaagaagc agttaaatct atactatatg caggttctga atttgatgga tttggatata
    41341 agcaacaatt taatttaggt ggagaagaaa atgaattgat gacttactca gctactcaaa
    41401 gtgcaatttg gattattctt ggacaaatgg atgaacaaga aagacttaag cagtatcaag
    41461 gttctataaa cctttgtgat aaacttatag aaagagcaaa aactgaagag gaaagagctg
    41521 agtatcagaa gaagaaagaa gtagctataa atataaaagc ttatttagaa gcattgttaa
    41581 aagcaggtcg tgaagagtta aagccaaatg atacaggaaa acctagtttg agtaatggtt
    41641 taactaagat taactttgaa aaaaatgaag atggtactta tgaaacagaa gctgtagcct
    41701 tagtaggtta tagtggtgta gtaaagttaa gactaccaga tggagtaact gcttatgatg
    41761 gagatggtaa tataataggt acaggtgaag tagaaatttc aacacaacag aaatttaaac
    41821 ttaagagtgt tgtaaaacca gatgccaaag ctaatatttc tgctgtatct tatgattata
    41881 tttttccaaa agctattcaa tattataagg cagtgcttga tttaggacaa aaagaccatt
    41941 catcttcatt accatctagt aagcaaaatt tattaagtta tacaatagag aaaaaaaatg
    42001 gtcaagaagt taactttaat ataggtctac caacagatga tgttgtaaat ccaccagtgc
    42061 caccaacaga tgatacaaat ggacataagc caaaaccatc accaccaata gatgatacag
    42121 taataaatcc accagtacca ccaatggatg atacaataat aaatccacca gtaccaccaa
    42181 cggaggatgc agtgttaaat ccaccagtgc caccaacgga ggatgcagtg ctaaatccac
    42241 cagtgccacc aacagaggat acagtgttaa atccaccagt accatcagta agtgatacag
    42301 tggaaaaaac tccagaacta tcaagagatg atacaataat aaaatcacca aaaacaggtg
    42361 atgaaactca gctaatgtca tatgtattta ttagtgtcat tgcaatttgt ggattagcgt
    42421 atcaatgtaa aataaaaaga aattaatcta gattattatt aagtttaaaa taaaaagtct
    42481 caaattgatt tataagtcat tttggggctt ttttatgtaa atataatatg caaatatagt
    42541 ttgtttaaaa atatatattt taattatatt cttaaattta tgattggata caggcattca
    42601 ttaattgttt gatgaataga aaaatgtttt gaaggtgaaa atagtattga aaaaataata
    42661 tactaagggt ataattcatt tgatttcatt tgtataaatt taattataaa ttttaaagtg
    42721 attatataaa tttaaatgct aattacttaa taaattttaa taataattat ttaataaata
    42781 attattataa tatgctagaa taaatatata taaataagtt ttgatgaggt actactataa
    42841 aggggggact ttatgttttc gataccagaa gtaaaaaaag tagaagaggt aatggataca
    42901 aaatttacaa ctatagacga agacacaaga attgaagatg caataaaaga aatgataaaa
    42961 agcaacacaa aaactctaat ggtaatagat tcatctgacc aattaaaagg cattatatcc
    43021 atgacggata tacataatct ttatgagatg cataaaaagt atgaaggtca accagtaaaa
    43081 cttataatga agaaggatgt aatatatgtc aacgaaggtt taaccttaga tgaatgtaga
    43141 gatataatga tattaaaaaa tatagggatt cttcctgttc ttagagataa taaaattatt
    43201 ggagttctaa aacaagagca cattagggac tatctatata tgcatttaga agattatgga
    43261 ttaactttga agtatattat aggtcaaatt aaagaaggaa tttgtgctat aaataacgaa
    43321 ggtgttgtta tcttgtggaa taagtttatg gaggaaaggt atgatataaa gtctgaagat
    43381 atagttggtc gaccgatgaa tgaatttttg gaaaatacta tttcagaaaa agtactaaat
    43441 agtaaagttg gaatgagtga cttgtatttt acagataaaa aagaaaatat gtatgcatta
    43501 gttcatgcaa atcctatatt ttataaagaa gaatttatcg gtgttgtatg tacagaagtt
    43561 gatgttacag aagctaagat attagctctt gaacttgaaa aagtaaatga tacattaaaa
    43621 tatctaaaga acgaagtcaa aaatttatct aaaggtagtt ttgataagat tttaggtaaa
    43681 agttataaat tggaaaaatc gaaagcgatt gcaaaacaag tggctagaac aaatagtagc
    43741 atatttattt ggggcgaaag tggtacaggt aaagaagtat ttgcaagagc tattcatgat
    43801 tatagtgaga gaaaaggtca atttatacct gttaactgta gtgccatacc aaatgagtta
    43861 tttgaaagtg agttttttgg gtatgaatca ggtgcgttta caggagcaag taaaaagggt
    43921 cgaataggta tatttgaact tgcaaaagat ggaactgtat ttttagatga aattgccgat
    43981 ttacctctta gtatgcaagc aaagttgctt agagtattac aggaaaaaga aataagaaga
    44041 gttggtggag ataccacaat aaaaataaat cctagaataa tatcagctac caataaagat
    44101 ttgagtaaaa tggtaaaggc agaaaaattt agagaagatt tatactatag attaaatgtt
    44161 gttgaaataa agattcctcc acttagagag agaaaagaag acataggatt attggttcat
    44221 agctttttag aggagatatg taaacaaaat aataagcctg ttcttacaat tagcaaagat
    44281 gtaatagata tatttcagaa ttatagatgg aaaggtaata ttagagaatt aaaaaatacg
    44341 attgaaaata ttgttgtatt gtcacaaaat tctaaaatag atgtggatga tgtaccaagt
    44401 tatatgatgg attctacaaa taatagtact gaagaagaag agtatccttt agatttaacg
    44461 aaggcaactc aaaaaattga aataaagaat ataaccaagg cacttaaaat gtctaatgga
    44521 aataaagcta aagcagctaa gatattaaat atacccagaa caactttgta ttataagata
    44581 gaccaataca aaatagatgt gtctaaaata tgacacatga ctaaattttg acaaaatgat
    44641 aaactttaat ttaaaaccta gtaaagccaa cgcttatata agtgttgtgt atatagatgt
    44701 gttaaaaaaa atgaaaaagt gttgattaat tgacactttt tttgtttgag aaaatgttta
    44761 caaatacaaa aaataacata ttttaaataa atatttatat aatatttggc taaaaatagc
    44821 gatagatgaa gaatctatta tagaaaaaat ctttttgtta ataagttggc ataggaattg
    44881 cttataatat aaagtgactt taagtgagaa aaaaataata ttaatcataa caaattatgt
    44941 aggttttaat ttacttaatt tctcagttaa ggggttacct gttgaggaat tgagatttaa
    45001 aataataaat aagaaaataa tgtaaggagg tattttatac tatgtcaata actttagaaa
    45061 cagctcaagc ccatgcaaat gacccagcag tttgttgttg tagatttgaa gcgggaacaa
    45121 ttatagcgcc agaaaactta gaagatccag caatatttgc agacttagag gattctggat
    45181 tattaacaat accagaaaat ggattaacta taggtcaagt actaggagct aagttaaaag
    45241 aaactttaga tgcactttct ccaatgacta cagataacgt agaaggatac aaagcaggag
    45301 aggctaaaga agaagtagta gaagaaacag tagaagaagc agctccagta tcagaagcag
    45361 cagtagttcc agtaagcaca ggagttgcag gtgaaacagt taaaatacac ataggtgaag
    45421 gtaagaacat aagcttagag atacctttat cagtagctgg tcaagcagga gttgctgctc
    45481 cagtagcaaa cgttgctgct ccagtggcaa gtgcagcagc agaagtagct ccaaaagttg
    45541 aagaaaagaa acttttaaga agcttaacta aaaaacactt taaaatagat aaagttgaat
    45601 ttgctgatga aactaaaata gaaggaacta ctttatacat cagaaacgca gaagaaatat
    45661 gtaaagaagc taatgaaact caagagttag ttgtagatat gaagttagaa ataataactc
    45721 ctgataaata tgaaacttac agtgaagctg tattagatat acaaccaatc gctactaaag
    45781 aagaaggcga attaggttca ggtataacta gagttataga tggagctgta atggtattaa
    45841 ctggtacaga tgaagatgga gttcaaatag gtgaatttgg ttcttcagaa ggtgagttaa
    45901 atactactat aatgtggggt agaccaggtg ctgctgacaa aggtgaaata ttcatcaaag
    45961 gtcaagtaac aataaaagca ggaactaaca tggaaagacc aggaccttta gctgctcacc
    46021 gtgcatttga ctatgtaact caagaaataa gagaagcatt aaagaaagtt gacaactctt
    46081 tagtagttga tgaagaagta atagagcaat acagaagaga aggtaaaaag aaagttgttg
    46141 ttataaaaga aataatggga caaggtgcaa tgcatgataa cctaatatta ccagttgagc
    46201 cagttggtac attaggagct caaccaaacg ttgacttagg aaacatgcca gttgtattat
    46261 ctccacttga agtattagat ggtggtatcc atgcattaac ttgtatagga cctgcatcaa
    46321 aagaaatgtc aagacattac tggagagagc cattagtaat aagagctatg gaagacgaag
    46381 aaatagattt agtaggtgtt gtatttgttg gttctccaca agtaaatgct gagaaattct
    46441 atgtatctaa gagattaggt atgttagttg aagctatgga agttgatgga gctgtagtaa
    46501 ctactgaagg tttcggaaac aaccatatag atttcgcatc tcacatagag caaataggta
    46561 tgagaggtat accagtagtt ggtgtaagtt tctcagctgt tcaaggtgct ctagttgttg
    46621 gtaataaata catgactcac atggtagaca acaataagtc taagcaaggt atagagaatg
    46681 aaatattatc taacaacact ttagctccag aagatgctgt tagaataatg gctatgctta
    46741 aaaatgctat agaaggtgta gaagttaaag ctcctgaaag aaaatggaat ccaaatgtta
    46801 aattaaataa catagaagct atagaaaaag ttacaggaga aaaaatagta ttagaagaga
    46861 atgagcaatc tctaccaatg agtaagaaga gaagagaaat atacgaaaaa gacgaaaact
    46921 aaaatttaga tactaactaa gatttagaca ataacataaa tttagatcca agtttaaaac
    46981 agtatagaga ggtagaatta taatggatag gttaaaatat atctcatcag agacttttta
    47041 tgaaggtatt atagttgaca tcaaaggcgg tggagtgact atagacctaa aaggtagact
    47101 tggacaattt aaaataccta atagaatgct tataactgac tacgaactta agataggtca
    47161 agaagttgga ttcatgctaa gctatcctga ggtattaagt ccagagccta atcaagagta
    47221 tgtagaaaat attaggagag aaaaagaaaa acaagcagaa atgcaatcaa aacaagaaga
    47281 aaaataataa ataatcgttt gaaaatagaa gggagaggaa atatatgagc cttacaacag
    47341 tacaaggact tcaatctgaa atattcgttc caataacacc tcctccagtt tggactcctg
    47401 taactaaaga attaaaagat atgactatag ctttagctac agcagctggt gttcatttaa
    47461 aatctgacaa gagatttaat ctagcaggag atactacatt tagagctata cctaatacag
    47521 ctacagttga tgaaatgatg gtatcacatg gtggatatga caatggagat gtaaacaaag
    47581 atataaactg tatgttccct atagatagat tacatgaatt agctgcagaa ggatttatca
    47641 aaggagtagc tcctatgcac tatgcattca tgggtggtgg aggaaaccaa catgtcttca
    47701 ctgaagaaac tggtcctgct atcgctgcta aacttaagga agagggagta gacggtgtag
    47761 ttatgacagc tggctgaggt acttgccata gaactgccgt gatcgtgcag agagcaatag
    47821 aggaagctgg aatacctaca ataataatag cagctcttcc tccagtagtt agacaaaacg
    47881 gaactcctag agcagttgct ccattagttc caatgggtgc taatgctggt gaaccacata
    47941 atatagaaat gcaaacacat atattaagag atacattaga gcaattagtt gcaataccat
    48001 ctgctggtaa gatagttcca ttaccatacg aatataaagc tcacgtttaa aatgtaattt
    48061 atatttgaaa atatagaacc cttctcctac acggttagga gaggggtttt aagaacaaag
    48121 gtggatatta tggaagaaaa aataatgaga agacttgtta taaaaccgtt tcatatgaat
    48181 gaagttaatt tcggttcaaa aacttctata aagaaagatg tacttacaat agatttatca
    48241 agtatagatg aaataaaaga aagagaagag ttaataacag acataaaagt agacattata
    48301 aaacctggag attatgacag agaaattaat actattatgg acattatacc aatatcaaca
    48361 aaagttttag gcagactggg agagggtatt acacatactt taacgggtgt atatgtaatg
    48421 ttaactggtg cagatgaaga tggaaatcaa atgcatgaat ttggttcttc agaaggaatt
    48481 ttgaaagacc aaatggtatt tgggagatat ggaactccat cagttgaaga ttatataatc
    48541 catgtagatg taactttaaa gggaggttta ccttttgaaa gaacacttcc acttgcagca
    48601 ttcagagcat gtgatgattt tatacaagaa ataagagcgt ctttgaaaat ggaagacgga
    48661 agaaatgcta ctcaagttcg tgaatatttt gacaaaattc gaccaaatgc aaaaaaggtt
    48721 gtcatagtaa aacaaatagc aggtcaaggt gctatgtatg acaatcagtt attctcaaag
    48781 gaacctagtg gatttgaagg aggaacatca attatagata tgggaaatgt acctatgatt
    48841 atatctccta atgaatacag agatggtgcc cttagagcta tgacttaaga gaggtggata
    48901 ttatgggaat aggaccttca acaaaagaaa catctcttca tcactttaga gacccacttt
    48961 tagacatagt tgaaagtgat aaggatgtag atttacttgg agtaatagta gtaggaactc
    49021 cagatggaaa tgaaaataaa acctttgtgg gacaaagaac ggccgcttgg ctggaagcca
    49081 tgagagtaga tggagctata gtttcatcag atggttgggg aaactcacat gttgactacg
    49141 ctaacacatt tgaggaaata ggaaaaagag atatacctgt agttggagtt acatttaatg
    49201 ggactcaagc taagtttgtt gtaagcaatc aatatatgga taccatagtt gatatgaaca
    49261 aatcaaaaga aggtattgag acagaagtag ttggagaaaa caacacaaat gaaatagatg
    49321 ctaaaaaagc tttggcattt ttaaaactta aaatgagaaa acatggataa aaaatttaag
    49381 taagggaatg agttttgtgg gaatttctac atcaatgaaa aacacatcac ttcatatatt
    49441 tagagacccg ttactagatt tgatagataa tgattctgac atagacttgt taggagtggt
    49501 tgtagttggg acatcagagc acaatgaatg gaaaacattt ttagcaacta gacttggaag
    49561 atggattgaa tcattgcgac ctgatggagt gattataact ttagatatgg caggaaacca
    49621 gcatattgat tttacaaatg ctatagcaga gtttgtaaaa tcagatatac ctacagtagg
    49681 tcttactatt atgggagcag atggattagt aattaccaat ccatatttgg ataaagctac
    49741 cataattgat tataaaaaga caacaggcta catagaaaca gaagtagttg gagacaatca
    49801 catggatgaa gttgatgtta aaaaagcatt ggctttccta aaattaaaaa tgcgtaaaga
    49861 cgcaaaataa acctaagggg gaatttgata tgaaatttag cagaagtata caagctatag
    49921 actctcatac agcaggtgaa gcgactagaa tagttgtagg tggaatacct aacataaaag
    49981 gaaattctat gcctgagaaa aaagaatatt tagaggaaaa tctagattat ttaagaactg
    50041 ctataatgtt agagccaaga ggacataatg atatgtttgg ttctgtaatg actcaacctt
    50101 gttgcccaga tgctgacttt ggaataatct tcatggatgg tggcggatac cttaacatgt
    50161 gtggccatgg tacaatagga gctatgacag cagctataga aacaggtgta gttccagcag
    50221 tagagcctgt aactcatgta gttatggaag ctccagcagg aataataaga ggagacgtta
    50281 cagttgtaga tggaaaagct aaagaagtat cattcttaaa cgtaccagct ttcttatata
    50341 aagaaggtgt tgaagttgac ttaccaggtg ttggaactgt taaatttgac atatcatttg
    50401 gtggaagctt ctttgctata atacatgcaa gtcaattagg tttaaaaatc gaacctcaaa
    50461 atgctggtaa attaactgaa ctagctatga aacttagaga tataataaat gagaaaatag
    50521 aaatacaaca tccaacttta gctcatataa aaactgtaga cttagttgaa atatatgatg
    50581 agccaactca tccagaagct acttacaaaa atgtagttat atttggtcaa ggtcaagttg
    50641 acagatctcc atgtggaact ggaacaagtg ctaaattagc tactttacat gctaaaggtg
    50701 aattaaaagt aggagaaaaa ttcgtatatg aaagtatatt aggaacttta ttcaaaggtg
    50761 aaatagttga agaaactaaa gttgcagatt tcaatgctgt agtacctaaa ataactggtt
    50821 ctgcttatat aactggattt aatcattttg taatagatga agaagaccca cttaaacatg
    50881 gatttattct taaataagta ataaataaat taggaaatta aaatagaata gtagccactt
    50941 gtcggttgct attctatagc ttttaggcta taagattcag aatatatgaa aaaataaaaa
    51001 aataggagga tggattatgg tagcaatctt aaaggcatta tatgtagtat tcgcagcaat
    51061 ctttgcagtt gtgtttggta aagacgtagc taaagcaaac aaagagggga aactagaaga
    51121 acaaagtact ccaaaagttg ctgtaacagg atttataaca gacttctttg atacattagg
    51181 aatagggtca tttgctccaa caatagcaat gtcaaaggct ttaaagttaa atataccaga
    51241 taaaaaaatg cctggtacat taaacgtagc acatactatt ccagttgtta cagaagcatt
    51301 catatttaca tcaattatcc cagtagatgg tgttacttta gtatctatgg ttgtggcagc
    51361 agcagttggt tcatatatag gtgcaggaat aatagctaag atggacgaga gaaaaataca
    51421 acttgttatg ggtgtaactt tagcattaac agcaatatta atgttattag gtcatccttg
    51481 gattaacgta ttaccaggtg gaggaaatga attaggtctt actggtgcta aattagtaat
    51541 aggtgtaata ggtaacttta tactaggagc tttaatgaca gctggtatag gtctatatgc
    51601 tccaggtatg gcaatggttt atttcttagg aatgtctgca aaagttgcat tcccaatagt
    51661 tatgggttct tgtgcattat taatgccagt tgcaagtatg aaattcataa aagaagatgc
    51721 atatactaaa aaagcatcag ttataatagc tatatgtggt ttaataggag ttttcgtagc
    51781 tgcatatata gtaaaaactc taccaatgga tatattaaaa gcattagtaa tagtagttat
    51841 agcttatact tctgctacaa tgataatggc tgcaaataaa aacaaaaaga ctgcttagtt
    51901 aaagactact tagtgtttat taaatattac agctaataat aaagattata aactgcttta
    51961 aaatattgaa ttaatatttt agggcagttt tttatttact aaattaatat aaagcaatta
    52021 acatgccaat tatgtaatat atatagtgat ttagtagatt taatctaaaa aacgttgtat
    52081 ttttaaagaa taaagcataa tttaaagcta aatatttaaa ttttataatc aataagttca
    52141 ataaatgttc atatattaat acagattaat aaaaatataa cctgtaataa gtctaatata
    52201 acttataatt aagaaaaata agtttataat gactcaatat tcatctgaat tatttcaata
    52261 aatttaattc gttgaagttg cttatataga gtgaataaat ttaagttata tatgacttat
    52321 taattatata ataggatttt tataattaat acaaaactga aataggtagt ttaattagta
    52381 tatgtggtac aaaaagataa taattttata attataaaag tgaaatatta aatgaaattt
    52441 ataactaaat aaaaactttt aaacagcaat caaagatttg taataaaata catcccttat
    52501 aaatatattt attatataag ctgataccag aaatataaga attaacaatt gtggagggat
    52561 aaaatatgat agctgttaaa gatgagaata acgtagtaaa cttaagaggg gagttagaca
    52621 ataagctaga atttagccat gagatatttg gagaaaaatt ttataatatg aaaataaaaa
    52681 taaacagact aagcgattct tttgatatac ttccaatgac tgtatcagaa agacttctcc
    52741 aagatattga ccttgataaa caaaatttag tcaatgtcgt aggccaatta agatcatata
    52801 acaaaacatt aaataataaa aatagattag tgcttacagt gtttgtcaga gaaataaaaa
    52861 gtatagacga ggaaaataaa gaccctaata gtatattttt agatggatat gtatgtaagg
    52921 aacctgtgta taggaagaca cctttaggaa gggaaataac cgatttatta gttgctataa
    52981 acagacctta taataaatct gattatatac catcaatagt ttggggtaga aatgctaaat
    53041 ttgcaaagaa tctaaaggtt ggtgatagaa tacagctttg gggtagggtt caaagtagag
    53101 aatatgagaa aaaaatagat gaaaataatg tggtcaaaaa aatggcatat gaagtatcca
    53161 tatcgaaaat aaaaaaattg gatgaaaata acaatgaata aacataaaaa atagactgat
    53221 ttttatgaat aaaatcctaa taaatttggt ataatatcat attaaaatgt ataaagattg
    53281 tttaaaaaaa tactaatgaa atatctcttg aatagttgct cgccatttat tataatgtaa
    53341 tctgtacata atttataatt gaggaaatga agaggtgaag cattgtgaaa agcatattat
    53401 gtcagataaa taaacagcca gttaaagcta aatatacatc tgatgaatta gaatgttttt
    53461 tggatacaat tgagtataat gtaggtgata aaatattgct tgttggtcat ataggaaacc
    53521 taggcaagag attgagaggt cttggaactt ctgtaactat actggagaat agtaattatg
    53581 aagatgtctg ttattctcta gtgtataatg aaaattgcaa tgtagttaaa ggtaagttag
    53641 agtttctacc atttgatgat aatcagttca acaagataat aatagttgac caatttaatg
    53701 ttattacaga ttgtgaaaaa gcttcatctg aaatacaaag agtgttaaag ggcaatggag
    53761 aggttatatt agaggattta aatttaaaaa atttaaaagt taagttaaac tatcttaaac
    53821 ataaattttg tggttctgtt gcaaagattc actatccaca tgaagtattt aatatatttt
    53881 caagattaaa ctttgatggt atgattaaag agtcaaataa attaaaatat atttatgtgg
    53941 gaaaaagaag ataaatgagt taaaatataa atatggatat aatataaaag actaggttaa
    54001 gcctagtctt ttgttataag gagatgttta gatggaaata aattatgagt taataataat
    54061 tgttatgctc tttgtaatcc tgatgtcaat ccaatttact ttaaataaga tatacttgat
    54121 tcttaaagaa ataagacaaa tacttatgct aaagaaaaat aaggaatgat gattatgata
    54181 ggtttagaat atataaaatc tgatattcaa aatatagctg aagctatagt atcagtactc
    54241 aatatagatg taactatagt aaataaggag ttatttagga ttgcaggtac aggagtatat
    54301 atagacaaaa taggtgagaa agtagataaa tatacggctt ttaaaaaatc acttacagaa
    54361 cagattacaa tactaattga tgacccaaag agtagtgata tatgtaggga atgctataaa
    54421 agtggggctt gtgtagagtt tgcagaggtg tgttgtccta ttatatgtga tggcgattct
    54481 catggtgtta taggccttat agcctttaca aaagaacaag cacaaattat agaaaataat
    54541 aaaagtggtc ttataaactt tttaggcaaa atggcagacc taatatctaa taaattaaaa
    54601 gcacaaatta aaacttatga gcttgaatta gaaaagaaaa aattagagac actattaaac
    54661 aatatggaca aagctgttgt gtctattgat gtggatggaa aaattgataa atataattca
    54721 aaatttaaag agcttttcaa tataaaagat agtataactg gcaaaaacat atttgtcgag
    54781 ttagatttta taaagaaacc ttctataaat aactttaaga aggacaaatc ctgtagtttt
    54841 ttttataaaa gatacggata tgattcgaag ggaatataca acatcaataa aatagtatta
    54901 aaaaatgagt taaagggata tgttattgat tttatagata aaagagatgc tataaaaaac
    54961 tacaataaga tgaataaaga ttatagaata aaattggaaa acataattgg agaaagtgta
    55021 gctataagaa attctaaaaa ggaagcccta atagcttcta aatcaacatc aacagtactt
    55081 attactgggg aaagtggaac gggtaaggag ctatttgcaa gagccataca caaccatagc
    55141 aatagagtag ataatccttt tatagctgta aactgtgctg ctataccgga taatttatta
    55201 gagagtgaat tatttggata tgaagaggga gcttttactg gagctaaaaa aggtggaaag
    55261 cttggaatgt ttgaagtagc tcataaggga agtatatttt tagatgaaat aggagatatg
    55321 agtttgcatt tacagtcaaa gttattgaga gtattacaag aaaaggaact taataaaatt
    55381 ggaagtaaat caaatgtttc aatagatgta agaattattg ctgctacaaa taaagattta
    55441 gaaagaatgg ttcaaaatgg cacttttaga gaagatttat attatagatt aaatgttata
    55501 cctataaaat taccaagttt aagagagaga aaagaagata tcccacttat aatcaagcat
    55561 atggttaaag agtattcaaa aaaattagat aaaaatgtta ttgacataga tagcagggtt
    55621 gttgatgcta tgatggaata taagtggcca gggaatataa gagagttgca gaatattatt
    55681 gaatatagtg tgaatatgtc ttcttcttca ataatcacaa tgaatgtaat tcctcaaaaa
    55741 attaagaata cctctgtaga agagttagaa gttaaaagcg ataggataat tccacttgat
    55801 gaactagaga agattgagat aataaaagct ttaaataagt ataaagatta taaaaaagat
    55861 aaagaattaa cagctaaagc acttggaata tcaagagcta cattatatag aaaaattgaa
    55921 aaatacaata taatttcata gtaatataat aaaaagctat ataaaattta aatttttcta
    55981 aattcataac tttaaagaaa gctttaaact tatactataa gtgttttgca gaatcttttt
    56041 ttatgaatta aaaaatggtt tttataagtt aaaaaataat atatttgagc cgtctcaaaa
    56101 tgatatagaa tctcattttg agactttttt ttgtcttttt gcgaaattgt catatgtttc
    56161 tccattttaa agaatataaa tactctatac aaataaaaaa aatacataaa tagaggcagt
    56221 cataccaatg gttatagaat ataagactaa aaatataaaa agatataaaa aatatggcat
    56281 gtattttgct ataaatatag ataagaaatt atttaactaa ttatttgagt actaaatcta
    56341 aacttaattg ggaggtttat atataatgag agatataaga aaagaattag tggaaatgtt
    56401 aaaggcagaa gttaaaccag cagtagggtg tactgaacca gtagccttag ctctagcatg
    56461 tgcaaaggca aaggaattat taggagaaga aatagttgaa aatcgtatgt tagttagtcc
    56521 tagtatctat aaaaatggta tgtgtgtagg tataccaggt actgaaagat taggattaaa
    56581 aattgcagca gctctaggta tagtaggtgg acattctgaa aatggattaa gtgtgttaga
    56641 aactctaaca aaagaggaag ttaaaatagc tgaggattat atggataata ctccactatc
    56701 aataacacct gctgatacaa gagagaaagt atttatagaa gttgtgttaa aaggaaaaaa
    56761 tcatattgct aaagtgagaa taagaactaa acatgataat tttacgttct tagaaaaaga
    56821 tggagaagta ttattagaca atgaaccaaa agtatcagct tcaaatgatg cggcagaaaa
    56881 agctgaaagt ttaatggata cagtaactat acaagaatta ataaaaaatg tagaagaaat
    56941 tgattttaaa gatatagaat ttttactaga tggagtaaaa atgaatgaag agatggctga
    57001 atatggatta aaacaaaaaa ctggtattgg tgtcgggtat ggaattaaaa agtctataga
    57061 agaaggtctt ttaggtaatg atgttataaa ttatgcaatg atgttaactg ctggagcttc
    57121 agatgcaaga atggcagggg taaaaatgcc tgttatgagt tcaaatggaa gtggaaatca
    57181 tggattaaca gcaattcttc caatcgttgc ttataataaa aaattcccac aatctgatga
    57241 aagactagca aaagctttag ctatatctca tctagtaact ggttatatta agaactatac
    57301 aggaagatta tctgctgtat gtggatgtgg tgttgctgct tctactggag caactgctgg
    57361 tatctcttgg cttatgaatg gtactgaaaa gcaaatagaa ggagctatag aaaatatgat
    57421 agctgactta agtggaatga tatgtgacgg tgcgaaagct ggttgtgcat taaaattatc
    57481 ttctgcagca tctgcagcta tacaaagtgc tataatagct aagcaagatt gttttgtacc
    57541 accactaaat ggtatagttg gttcaagtgt tgagcaaagt atacaaaact taggtagagt
    57601 aagtgacaaa ggtatgtcta taacagatga gataatctta aatgtaatga atgatatgaa
    57661 taaagttgac tagtacttta taatatgttt tgtattatga ggtataacaa aaatagcata
    57721 aataaattta attagtaccc tctaataaaa tatgattatg tataaattta tgtataatag
    57781 aaaaaacttg ttagtgcaag ttttttcttt ttttgtctaa aatatatagt atgtaattta
    57841 gtgtggatat atgaactact taaaatataa gatacattgt taataattgt tgaatgaaca
    57901 taaaaactca ataatattga ctaatattga ataagagtat tgaaaaagtg agcaatctct
    57961 tataaaatta agaaggatta ttacaattgg aggtcttttt atggatatag aaacaaaaaa
    58021 atgggaagta ttgtattcag aagaaaaaat taaagataaa ttaagggaat taggagcaat
    58081 tatagaaaaa gattataaag ataaaaatct tatggtagtt tctctattaa aaggtagctt
    58141 tatattttgt gcagacttag ttagaaatat aaatttacca cttagagtta attttatgac
    58201 tacatctagt tatggaaaca atgaagaaag tactggaagg gttaaagtag tttcagatgt
    58261 gactactgat atagcaggat atgatgtttt ggttgtagac gatattactg attctgcact
    58321 tactatggat tttgtgttaa aacatttaaa agctaaaaat cctgctagtt taaaatgttg
    58381 tgttcttttg gataaaccaa gcagaagaaa agtcgattta gtgccagatt attgtggatt
    58441 tgaaatagaa gataagtttg tggttggata tgggtttgat tttggtgatt attatagaaa
    58501 tgttccttat atattcaatg ttactgatga agatagataa gcaattatat aattttgtgg
    58561 atgccttaat atgattttta ttaatcgtgt tgaggttttt ttatttacaa agtaattaaa
    58621 gtagtattaa attaatttta tgcaatttaa ttatctattt tttataacat aataaaaaaa
    58681 ttttaaataa ttgatggaaa atgagttttt taattgtatt aataattgta aaagagtact
    58741 aataattgta aaagatttta caaaaaagta atgaaattca agaatcaaag catatatgtt
    58801 gatataagca aatagataca ttatcacata agaaattgtc gattcatata attatataga
    58861 gtaatactca atatttatag agtaatactc taactttaaa aaaggaggat taattatatg
    58921 agtgatattt caggtccaag tttatatcaa gatgtaggtc caacagggcc aacaggtgct
    58981 actggtccaa caggaccgac ggggcctaga ggtgcaactg gagcgaccgg agcaaatgga
    59041 ataacaggtc caacaggaaa tacgggagca accggggcga atggaataac gggaccaaca
    59101 ggaaatatgg gagcgactgg agcaaatgga acaacaggct ctacaggacc aacaggaaat
    59161 acaggagcga ctggagcgaa tggaataaca ggtccgacag ggaatacagg agcaaccgga
    59221 gcaaatggaa taacaggtcc aacaggaaac aaaggagcaa ctggagcaaa tggaataaca
    59281 ggctctacag gaccaacagg aaatacagga gcgactggag caaatggaat aacaggtcca
    59341 acagggaata caggagcaac tggagcaaca ggtccaaccg gactaactgg agcaaccgga
    59401 gcaaccggag caaatggaat aacaggtcca acaggaaata caggagcaac cggagcaaat
    59461 ggagtaacag gtgctacagg cccaacagga aatacaggag caacaggtcc aaccggaagt
    59521 ataggagcga caggagcaac aggaacaact ggggcaacag gcccaatagg agcaaccgga
    59581 gcaacaggag cagatggaga ggtaggtcca acaggagcag taggagcaac aggtccagat
    59641 ggtttggtag gtccaacagg cccaacaggc ccaaccggag caactggagc aaatggtttg
    59701 gtaggcccaa caggcccaac cggagcaact ggagcaaatg gtttggtagg tccaacagga
    59761 gcgacaggag caacaggagt agctggggca ataggtccaa caggagcagt aggagcaaca
    59821 ggcccaacgg gagcagatgg agcagtaggt ccaaccggag cgacaggagc aacaggggca
    59881 aatggagcaa caggcccaac gggagcagta ggagcaaccg gagcgaatgg agtagcaggt
    59941 ccaataggtc caacaggtcc aaccggagca aatggagtag caggagcaac aggagcgaca
    60001 ggagcaacag gggcaaatgg agcaacaggc ccaaccggag cagtaggagc aacgggagca
    60061 aatggagtag caggagcgat aggaccaaca ggcccaactg gagcaaatgg agcgacagga
    60121 gcaacagggg cgaccggagc aacaggagca aatggagcaa caggtccaac cggagcgacc
    60181 ggagcaacag gagtgttagc agcaaacaat gcacaattta cagtgtcctc ttcaagttta
    60241 gtgaataata cattagtgac atttaattca tcatttataa atggaactaa tataactttt
    60301 ccaacaagta gtactataaa tcttgcagtt ggagggatat acaatgtatc tttcggtata
    60361 cgtgccacac tttcacttgc aggatttatg tcaattacta ctaactttaa tggagtagct
    60421 caaaataact ttattgcaaa agcagtaaat acacttactt catcagatgt aagtgtaagt
    60481 ttaagctttt tagttgatgc tagagcagca gctgttactt taagttttac atttggttca
    60541 ggcacgacag gtacttctgc agctggatat gtatcagttt atagaataca atagtttata
    60601 tgatgaaaag attataaaat aataaacaat atgatttcat ataccaataa atagaataat
    60661 atttaatagg tttatatgat gaaaagacta taaaataata aacaatatga tttcatatac
    60721 caataaatag gataatattt aataggttta tatgatgaaa agactataaa ataataaaca
    60781 atatgatttc atataccaat aaattaggat aatatttaat aggtttatat gatgaaaaga
    60841 ttataaaata ataaacaata tgattccata taccaataaa taggataata tttaataggt
    60901 ttatatgatg aagagattat aaaataataa acaatataat tccatatacc aataaataag
    60961 ataatcttta agaaaaatga ttatatttaa aaggtaaaca taaaatttat aaacttttag
    61021 aatagaaatc tcaatcaatt agatattcaa attgatgaat atgaatacct aaatagattg
    61081 agatttatta tgtacaaaac ttatcctaat atatctgaca ttttataaag cccagattgc
    61141 ttaccaatta aaaatttagc tgcaactata gaaccgtttg caaatacttc atcagattga
    61201 gaatgatggc ttaatgtaag aacttcatta tcacctgcaa atacaacatc atggtcgctg
    61261 attatattgc cacctcttat agagtgtatt ccaatttcat ttggttttct tttacaatct
    61321 ctaccatatc taccatgtgt attttcactt tcaggcaaga cttctctaat tgcattagct
    61381 atcatagtag cagttccact aggggcgtct tcttttctat tgtgatgttt ttctatgatt
    61441 tcaatatcaa aaccttctaa catctttgaa gcatccttaa ctaattttat taatatattc
    61501 actccaagag atgtatttga tgataataat ataggaatgt tttttgatgc ttcttctatt
    61561 ttatttaagt cattttcatc atatccagta gtagctaata ctacaggtgt attatttttt
    61621 agagcatatg acaatattgg ctctaaagtc tcatgatgtg aaaagtctat tattacatca
    61681 gttttttcag ttacatcagt cattgttttg taaagctttg tatcactatg atgacctttt
    61741 tcatcagcag acctagctac accacaaacc aactctaatt cattatcttt ttttacacat
    61801 tctgctaaaa ctcttcccat tgttccatta tagccactaa ttataacttt caacataaat
    61861 tcctcctatg aaattaataa aaatttgtta tatttctata agtttatttt atcactaata
    61921 taatttatat aaaataatat tagtgataat aagcttacaa tttatcttac attaaaaaat
    61981 ttaagtggat ttttcaaaat atagataaat ttctttttca ttgtataaat gataaaaata
    62041 tatttgactt cataccaaaa agagtgcccc atgaactaaa aagttaattt tgaaatacca
    62101 tattcatata tcatatgatt tatttggaaa tcaatattaa tacattaaaa taactaaata
    62161 catgtatgca taaagatgta taaaaaatat ataaacatat agtattaatt ttaaattcaa
    62221 caatttaatt gttaaaagtg ttattattaa attagaaata tcttaactta atatactgag
    62281 atgggagtga tagatatgtt aaaagaagaa aaaacttatc aagagaaaga cgcaaaagta
    62341 ttcaatggag tggcagcttt gataatgatt ttattatttt tagtagtttc aataggtatc
    62401 atggtttttg ggatagtaaa acttgatagt ggatttactg gaataggttc acttatgtta
    62461 attttgggac ttgtatttat agtagtagat tttatcctat tttttgggct aaaaatgatt
    62521 aatcctaaag aagctatagt tctagttttg tttggtaact attatggaac tataaaaaaa
    62581 gaagggtact attgggtgaa tccattttgt tcagcaataa acccagcagt atcaagaatt
    62641 aatgtatcga aatcttcatc tgatgaaaag gtagatatat caactaattc aaggggcaaa
    62701 aaagtatctt taaaaacaat gactcttaat aatgaaaagc agaaagtcaa tgatttattg
    62761 ggaaatccaa ttataatagg agtggttgta atttggaagg ttatagatgc aacaaaggca
    62821 gtatttaatg tagataatta taatacattc ttatctattc agtgtgattc tactattcgc
    62881 aatgtttcaa gactttatcc atatgatgta tctgaagatg gagatgaaaa atctcttcgt
    62941 ggtagtagtc aggaaatagc agatagatta aaagatgaat tacaatcaag ggttgatatt
    63001 gcaggaattg aagtgtgtga agtgagaatt actcatcttt cttatgcacc agagattgca
    63061 gcagcaatgt tacaacgtca acaagcagag gctataatag cagcacgtaa aaagattgtt
    63121 gagggggctg taagtatggt agagatggca ttgactaatt taagtgaaaa taatgttgtg
    63181 actttggacg aagaacgtaa agcagctatg gtaagtaatc tgttagttgt gctttgtggc
    63241 aataaagatg cacaaccagt ggtaaacagc agttctattt attaaattat aaaaagttta
    63301 atagtttatt ttattgatat atagaaaatt tagtagttca ttttattaaa ttatagaaag
    63361 attaatggtt tgctttattg aattataaaa agtttaataa tttattctat tgatatatag
    63421 aaaatttagt agttcatttt attaaattat ataaagatta atggttttca ctttattaaa
    63481 ttataaaaag tttaatagtt tattacattg atatattgaa aaattgaagg aaataaaaat
    63541 acttgtcagc aagaaataaa aatgatataa gaatgaataa gagaattgta aaaaaataaa
    63601 atgattataa ataaaagata aaaatattgt aaaaaagagg gtgcctctgg tgaattaaat
    63661 tcacacagag acaccttttt aattaatttt ttaaattagt atattattgt ttaattaata
    63721 gtatagtact atttaattaa tctaaatttc taaggtcttc cataagctta gttttgtcag
    63781 ccgttttttc atctttcatt tttataactt tagcaggaga accagcaaca acggcaccag
    63841 cttctacatc agtagttaca acagcaccag ctgcaacaac agcaccttta ccgattctaa
    63901 caccttcaag aataactgca ttagctccta ttaaaacatc atcttcaact ataacaggag
    63961 tagcagaagg tggctctaaa acaccagcaa caacagcacc agcacctaag tgaacatttt
    64021 taccaagagt tcctctagct ccaataacag cattcatatc taccatagaa ccttcaccaa
    64081 taacagctcc tatatttata acagctccca tcattacaac agcatttttt tctatagtaa
    64141 ccatgtctct tattattgca cctggctcaa ttcttgcatg ttcacttaaa gtatttttta
    64201 gaggaatagc agaatttctt ctatcatatt ctacatgagt atctgttata tcatttccat
    64261 gtttatctaa tacttccatt atatcctcat agtcacctac aaatatataa gaaccattac
    64321 ttccgaatac cttaaattta tcagttgatt ggaagtgtaa agagttagta tttacatata
    64381 ccttaacagg tgttttcttt ttaacttctt ttatatacct tgctatttca taagcatcgt
    64441 ttaaatttac catttgttaa ttctccttgt atttcattat atttctttta ttatatactt
    64501 atttgtcaat tttagtatat acttacttct tattatttat attttatttt agttagtttt
    64561 tattgtatag acatagtatt aaataaattt attatatatg tttgatttgt attgcgtatt
    64621 attatatcta tattgcatat gtttaattta tattgtgtat tattatattt atgctattat
    64681 cccaacatgc tgtccatatt ataaaatcct ggtttttgct taactaagta tttggcagca
    64741 gctatagaac cacttgcaaa gataccacga gattgagctt gatggcttat tgtaagaacc
    64801 tcattgtctc cagcaaatag agcatcatgt tcgccaacaa tatttccacc tcttatagca
    64861 tgaataccaa cttcatttgg ttgtcttttt gcactacgac catatctacc ataattattt
    64921 tcaacgtttg gcaaaacctc ttttatagcg ttagcaatca taacagctgt gccacttggg
    64981 gcatctactt ttctgttgtg atgtttttct attatttcta tatcaaatcc ttctagtaat
    65041 ttagctgcat ctttaaccaa ttttactaat acatttacac caagagacat attatatgat
    65101 tggaatacag gaataacttt agccgcttca cgtattttgt tcatttcgtc atcattatat
    65161 ccagtagtag caattactaa aggtgtttta gtctttaaaa cgtaagataa gatattatct
    65221 aaattagagt gatgagaaaa atctataact acatcagctt cctcaactat agtactcata
    65281 tcttcataaa ttttaaggtc gccttcatag ctatccagac ctctagctgc aacacaaacc
    65341 aattctaatt cattatcttc tcttatagta tcggctaaaa tcttacccat ttttccatca
    65401 taaccagttg ctataacttt taacataatt tcctcctatg attaagggct aacttttgac
    65461 caaacttact ttttaccatg cattaatctt tactatgcat taacttttag cccaaagtta
    65521 actaattctt tctttaatac ttctaaattt gctgggtcca tttctgctag aggtaatctt
    65581 aaatctccaa cattgaatcc caataaattc attgcagtct taactggtat aggatttact
    65641 tctataaata aagctgcgat tagagcatcc ataccaagtt gtaattttct agaaccttca
    65701 atatcgcctt caaagaattt agctaccaaa tcgtgagttt cttgagggca aacattagca
    65761 agtactgata taactccttg acctcctaaa gataataaag gaagtatagt atcatcatta
    65821 ccagagtaga tagcaaagtc atctggaact aaactagcta tttctgcaac ctgtcctagg
    65881 tctccactag cttcttttac agcaactatg ttatcaattt tagcaagttc aactataagg
    65941 ctaggactta tatttacaca agttcttcca gggacattgt aaagtataat tggaagttta
    66001 acactgttag ctattgtttc aaaatgacgc ttaagtccag ctttattagc tttattgtaa
    66061 taaggtgtta ttattaatag agcatctact cctaattttt cagcttcttg acttaagtta
    66121 actgagtgca tagtatcatt agaaccactt ccagctataa caggaactct tttattaact
    66181 ttttcaacaa catacttaat agtagcaagt tgttcttcat cagtcatagt attagcttca
    66241 ccagtagtac cacaagatac tatagcatca gtaccattag ctatttggta ttcaactaat
    66301 tcacctaatt tgtcaaaatc aactttgtta tcctttgtaa atggtgtaac tagagcaaca
    66361 gcagaacctt taaatatcat ataaaatcaa tcccctcttt tttatttttg tgttttatat
    66421 tacagttact tctaatgctt gtttttgagt tactattaat attttacaaa attatatatt
    66481 tatacaagtt tgtatattat actaaatcgt atgataaagc catttcagct atttgaattg
    66541 cgttagttgc agcacctttt cttatattat cagcaacaac ccaaagattt acaccattat
    66601 caacactaaa atctcttctt attcttccaa caaacacttc atctctatca tcaaattcta
    66661 cagcagttgg atattcgttt ttagcaggat tatcaactac tacaacacct ggagcttctt
    66721 caagtgtttt tactaaatca tctaactcaa atggattgtt aaactcaaca tttatagatt
    66781 cactatgacc attttttact ggaactctta cagtagttgc agttattttt aaatcgtagt
    66841 tatcaagtat tttcatagtt tcatttacca ttttcatttc ttctttagtg tatccatttt
    66901 cagtgaatga atctatatga ggaagacagt tgtaagagat ttgatgaggg tagaatccag
    66961 taggattacc gttcattcct ttctctaaat cttcaacacc tttaacacca gaaccagata
    67021 cagcttggta agtagagtaa acaactctct taattttgta tttatcatca agagctttaa
    67081 ggggaaccat agcttgtata gtagagcagt taggattagc tattataccc ttatgatttt
    67141 ttatggcttc tggattaacc tcaggaacta ctaaaggcac atctggattc attctccatt
    67201 gactagagtt atctactact aagattccat ttgaagcagc tattggagca tacttttcac
    67261 taatacttcc accagcagag aataatgcta tttgtatgcc tctatcagta aatgaagttt
    67321 cctttaattc ttctactata tattctttac cacaaaacat tactttagaa ccagctgatt
    67381 tagaagaaga gaataaaaat agattttcta ttggaaaatt tctttcttct aatactttta
    67441 aaaatgttct acctaccatt ccagtagcac caactattgc tacatttact tttttcatat
    67501 aaattcaccc caattttaaa ttattaaaac attattttat tttagttata caagtaagat
    67561 atgttaatat ttttatatat ccaaaaactt taatattata ttaacaactt taattatata
    67621 caaaaaacgt acaaaggtat actttgtacg tctaatttat cactcaaagt aaaccctgta
    67681 gctcatcacc tacaaaaata agtgacagta ttacacatgt tatgtgcaat cccagaaaat
    67741 attattgcaa gaaatatttt cttcggctgt aaatcctttt tccaatcatt aacacctgcc
    67801 agctactatt ggatactctt agttacagct acctctaccc taggttaata ggatattaaa
    67861 atttgattat tctaataata atacatattt aagaaaaaat caacttattt atataaatat
    67921 tgctaaaatt taaatccaaa atttgtcaat tcttgtttta acacattaag attagtttct
    67981 tccatttcag ctagaggaag tcttaaatca ccaacattaa aacctaaaat gttcatggca
    68041 gttttaacag gaactggatt tacttctata aataaagcag caattaaagc atccatatca
    68101 agttgtaatt tttttgagcc ttcaatatca ccttcaaaga atttagttac taaatcatgt
    68161 gtttctttag gacatatgtt agcaagtaca gagataacac cacttccacc taatgataat
    68221 agtggtagta tagtatcatc attaccggag tatatagcaa agtctttagg tactaattta
    68281 gctatttctg caacttgagc taagtctcca cttgcttcct tcacagcaac tatattatct
    68341 attttagcaa gttcagccac aacagatggc tttatattca ctttagttct tcctggtacg
    68401 ttgtataaaa taattggcaa cttaacgcta tttgctattg tttcaaagtg aagtttaaga
    68461 cctttctcat tagtcttatt atagtaagga gttattatta aaagaccatc cacccctaat
    68521 ttttcagctt cttgactcat atgaacagac aacatagtat tgtttgaacc agtacctgct
    68581 ataacaggta ttctcttatt aactttttca actgtatatt ttattacagc aaaaatttca
    68641 gattcactca tagtagtcgc ctcacctgtt gttccacaaa caactagtgc atctgtgcca
    68701 ttctcaatgt gatattcgat taattcacct aatttttcaa agttgacatt attatcctct
    68761 gtaaatgggg taactaaagc aacagcagaa cctttaaata acatataatc aaatctcctt
    68821 ttttatctaa atttaatttt ttaagtacaa taataattat agtacaaatt aattaatttt
    68881 aataggtata gttaatatct taactgttta aataagatat ttatattata ttaatattag
    68941 aaaaatttta aataaatgtt ttattctcaa aatatgcata ttaatttaat aaaatatacc
    69001 aaaatggaaa taaaaaataa attttatgag aatttaataa ctaataatta atatatttag
    69061 gttataataa atatgtgcgt aaaatctaac aataagcaat aataccgtaa atttaggagg
    69121 aataatatgg atactttaaa ggaacttttt aaaataggaa gtggaccttc aagttctcat
    69181 actatgggac cacaaagagc agcagagaga tttaagaatg aaaacccaga tgcagaaagt
    69241 tttagagcaa tattatatgg tagtttggca gctacaggga aaggtcactt aactgactat
    69301 ataattgaaa aaactatagc acctaaaaaa gtcgaaattg tttgggaaga agatattata
    69361 aaagattttc acccaaatgg gatgaagttt gaagctttag ataaagataa aaatgtaaca
    69421 gctgaatgga ctgtatattc tgtaggtgga gggactatag cagaagaagg tcaaagaaac
    69481 agtaaaagca atagtatata tcacttagat actatggatg agatagtaaa atggtgcaaa
    69541 gaaaataata agactttggt agattttgtg ttggaatgtg aaccaaaaga cataaaagat
    69601 tatataaaaa ctataaaaga tgctatgaga aaatctattg atgatggact aagtacagat
    69661 gaaataatac caggcaagtt attattaaaa agaagagcaa gtacatttta taatgcatat
    69721 aaaaaagata agagcttctc aacacttgta tatgcatatg cactagcagc ttcagagcaa
    69781 aacgcttctg gtaatataat agttacagca ccaacttgtg gttctgctgg agtaatacca
    69841 ggaatattct ttgcaatgca ggatttctat aattatgatg acgaaaaaat aattgaagca
    69901 ctacttgtag ctggaataat aggtaatata ataaaaacta acgcttcaat atctggagca
    69961 gaggtagggt gtcaaggtga agttggagcc gcttgttcta tggcagcagc agcagtagca
    70021 tacttaaaag gtggaactat agaccatatt gaatatgcgg cagaaatagc acttgaacat
    70081 catttaggaa tgacttgtga ccctgtatat ggatatgttc aaattccatg tatagaaaga
    70141 aatgcaatgg cagctcaaag agcttatgat gcagctaatt atgcattatt aactgatggc
    70201 tcacattctg tctccttaga ccaagttgtt gaaacaatga aagaaactgg tatagatatg
    70261 atggataagt acaaagaaac agctaagggt ggacttgcta aacatttctt ctcttgctaa
    70321 aaataaaatt ttccaataat aattcctctg ttttgattta tgaaacaggg gaattattat
    70381 taatggtgaa ttatttaata atgcaaaata tttttatatt caatttagct ttttattttt
    70441 aattagtata acatgctata taatatttta attataaaga aatatagaaa tattttttaa
    70501 taaattagaa attggaggag attacatgag agaggcatca tatttacaag aacaacttta
    70561 taaacatagg aagtcattaa atcctattgc agagattggg agaaaagaat ataagacttc
    70621 aaaatatata agagattatc ttgataaatt aggaattgag tatgaagttt atttagaaac
    70681 aggtatagta ggtgtaatag aaggtaaaag acctaaaaaa gatattgctt ttagagctga
    70741 catagatggt cttcatagtg aagaaggggt aaaacattta tgtggtcatg atggacatgc
    70801 tactatatta cttggattaa ttgagtattt aaatgataat aaagaagact taaatgataa
    70861 tatagtattt atattccaac cagcagaaga aggtcctggg ggagcaaaag ctttaataga
    70921 tgaaggagtg cttagaaaat acaatattga tgaaatatat gggcttcata tatatccaga
    70981 gttaccagaa ggttatgtag gtacaagaga gggctatttt atggctcaaa taggagatat
    71041 tgacatagaa atagtgtcta aaagtggaca tggggctatg ccacaaaatg gtattgatgg
    71101 tatagtgata gcttcaaact ttgtaagctc acttcaaact atagtgtcta gaaatataag
    71161 cccaatagac aatgcagtgt tgactattgg tagaattgaa gggggagcta gaagaaatat
    71221 aatagctgaa aatataaaga tggaaggtac tatgagatgt ttcagcccag aagtgtatga
    71281 gaaaatgaag cttagagtta gagaacttgc tagagggttt gaattggctt ataactgtaa
    71341 ggttaatata aatattatag atgattatat tgctgttaaa aatgacaagg atttgtatca
    71401 agagtttgta gaggctattg gaagtgatac tgttgtagag ttagagccac ttatgatatc
    71461 agaagatttt tcttattatc aaaaagaagt tccaggatta ttttttatgt tgggttcaag
    71521 aaacgaagaa aaaggatttg taaatggtct tcataatata aactttaatt ttgatgaaaa
    71581 gatatgtgta aatgcattga atgtttattc aaaattatta aaatacaaag aagcaataga
    71641 ttaggaagat aagttataaa gattaaaaag cataaatacc taaatttaaa aaaagtgtat
    71701 taataaatac cccttacata tttgtataaa tttattttaa ttgacaaaaa tacaaataag
    71761 aaggggtgat ttttttgaaa gaaaaagtac aaagagaaaa gaagataact aatggcaaga
    71821 atactaaaat attgacaaat gatgatataa tgaaatatga gatagcctca gaactaggtc
    71881 ttatggataa agttggtgaa cgtggatggg caggacttac agctaaggaa gcaggaagaa
    71941 ttggaggtat gcttacatca cgcaaaaaga ggcttaaaaa gattgtggag gagcagaata
    72001 aaaaggatga gtcaatatag tgattttgcg tttgtatatg atgaacttat gaatgaagtt
    72061 gattataatg gttgggttaa atatatagaa gatataatag atagtgaagg tgtaaaagta
    72121 aaaaatatat tggaattggc atgtggcacg ggtaatctta caattccatt gactaaaaaa
    72181 aattacgata tagctggtat agatatatct gatgagatgc ttagtgtagc aagagaaaag
    72241 gcagaaaaag aaggagtaga attagtttta cttcaacaag atatatcaga gcttgatttt
    72301 gaaatatctg atttggactg tgtactttgt gcttgtgatg gatttaatta tataacttat
    72361 gatgatgatt tggaaaatgt attttcaaag acatatgaat tattaaagaa agatggaata
    72421 ttcatatttg atataagttc tttttataaa ttagccaaca tattgggaaa taacatgtat
    72481 ggagaaaata gagaagatat agcgtatatg tggcaaaatt actttgatga agaagagaat
    72541 ctaattgaaa tggaacttac attctttatt aaagatgaat gtggaaagtt tgaaagattt
    72601 gaagagatac accaacaaag agcatatact gaagatgaga tagttgatat gcttgaaaaa
    72661 tctggattta aggatataaa atattatggg gattttacat ttgacaaacc tagtgaagaa
    72721 agtcaaagaa tcttctttgt atgtaaaaaa taagatattc ttgactatat aagataatta
    72781 ttaaaaataa ccatgatata aaaatatata aaatgcagtt ttatagatta aaagtaaagt
    72841 gatgatattt tatgattttt attttctaat aattataaag ttttatagat aaaaattaaa
    72901 atataataac tattgcttag taaaattaaa ataaaatggg ttttgcccaa ggttaagata
    72961 gataagtatt tatagattaa aattaaggta gtaatataat aaaaataaga caattaacgg
    73021 gacatggagg aatattaatg agagattatg tactaagagc gacatcagga aatggtcaag
    73081 ttagagcatt tgtcgcaact actagaaata cagtagaaga agctagaaga ttacatgaaa
    73141 ctacaaaagt agcaacagca gcacttggaa gaacattaac agccacatct ataatgggat
    73201 taatgatgaa aaatgatagt gataaattga ctgtaataat aaaaggtgga ggtccaattg
    73261 gaactattat cgccacatca gactctaagg gaatggtaaa aggatatgta ggaaatccac
    73321 aagtagaggt tgaagactat ccaaatggaa agttaaatgt agcagcagca gtaggtacag
    73381 aaggtgttgt aaaagttata aaagacttag gtcttagaga accatataat gggacttatc
    73441 cattggtaag tggagaaatt gcagaagact ttacttatta ttttgctgta tcagagcaga
    73501 ctccatcagt agtagcttta ggtgttctta caaaagaaga tgaagtagag tttgctggag
    73561 gatttatagt tcaattaatg ccagatgcag aagaagagac tattgctaag ttagaggaaa
    73621 atgtagctaa attaccttct ataactaaca tgttaaaaga aggaaaatca ccagaggata
    73681 tattaaatat tgttttggat ggtttggaac ctaaaatact tgatacctgt gaagttgggt
    73741 ttatgtgtga atgttcaaaa gaaagagtaa aaactgcttt ggttgcaatt ggtaaaaaat
    73801 cattggctca aataatagaa gaagataaaa aagcagaagt tggttgccag ttctgtaata
    73861 agaagtatat gtatagtgaa gaagagttgc ttgaaatttt aaaggaaatg tagactataa
    73921 aaatagttgt attgatataa gtaatgttat agtaatatag taaagtcgta ttgatatagt
    73981 aattaaagta taatttatta ataatagaca tatttatatt aaaaaataag tttaataaat
    74041 ttttaagctt aataaatttt aagaattaag aagctttctg gctgtaatgt ttgcaatgtt
    74101 gcagttagaa ggctttttta ttttattata gttcgtgtca aagattgtat gaaacaataa
    74161 aatattgtaa aataatttgt atatttagac ctgattgaca caaaggttta taagatattt
    74221 gagttgatta tacgaaattc tatgaagtag taaccctgtg actttaatca tgggaggttc
    74281 agaagaagga gaaaatttta aatatggaaa gtaaaacgaa gtacatagga ataagtatat
    74341 taatattatt gatgatattt ttaattgcaa agaattttaa cggaaaactt gaaataccta
    74401 ttcctgagag taatagtaga aaatttaaat cagcagcagt gttttatcct caacatcaag
    74461 atgatgaggt tttatgggga ggaagtgcca ttgtagatgc tataaaacag tgtggtgttg
    74521 ataatgtata tgtggtatta gtatcagatg gttctggagt taacgttttc aaagctaaca
    74581 caaaatttag aaatttaact aggaagcaaa aggaagaact tagaaataac gagtttaaat
    74641 cagctttgag agagcttgga gtgaaacctc aaaatgtgat tatacttgca gatatagata
    74701 aaaaggaagg cacacattat gaattaatgg aaaagactat attggatttt gaacataagt
    74761 ttaaaggcaa tgtgacccat atagcccatc actataagta tgatgaccat ataatgcata
    74821 gaaagaatgg ggaagtttta aagaaactta aacgtgaagg taagataaaa gatgacttgt
    74881 attttgttaa gccaaaatat gtaaagtata taccaagaaa tgaaagagct atctataaag
    74941 caatggattt tgatgactac aataaggtta agagtgcttg ttatgaatat aaggttgtaa
    75001 attcaaagcg taaaatgtat ggtataggat atatttcggc acatagttat tttgaacatc
    75061 ttctaaatga ccctgaactt acgtctgtat taagtgaaga ttaatttctt ataagtagta
    75121 agttatgttt gataagttga ttggaatttt ctatagtttt gaaggtattg gaaatttagt
    75181 tttatttaaa gatttaaaga tagaggtttt tagtgtttaa aattttaaag ttaagttgaa
    75241 taattgtata gaattatttg tgaaagaaga aacagtgtaa aacatagtat cttatttatg
    75301 gttttaaaat cataggcaag atactttttt tatgtaacta ataccatttt gagattatta
    75361 acttaagaat tttatataat ttaacactca tatataatga tgatatttag gtagaataga
    75421 tgtaattacg cttaaataaa ataactgtat tttttataaa aatccaaacc ctacactata
    75481 ctaccagata aaatctacat gctataattt gacctgtgtt tataaaaaaa ggagtaatct
    75541 aataaaatag tatttcactt atgtataact aacaactatt attacgattt tctctaaata
    75601 atttaaagaa aaataatgca ggaggtaaaa tatgaacaat gaatttataa ttttaaaagg
    75661 ttgcaaagag aacaatttga acaatatttc cttaaaaata ccaaaaagaa aaataaccat
    75721 attcacaggg gtgtcgggtt ctggaaagtc atctattgta tttgagacaa ttgcaaaaga
    75781 atcacaacgc caactaaatg aaaggtttag tacatttgta agaagttttt tacctaagta
    75841 tggagaggtt aaagctgatt gtatagaaaa tttgtcaaca ccaattatca tagaccaaag
    75901 tagacttggt ggaaattcaa ggtcaactct aggtactatt acagatgtaa attccttttt
    75961 aagagcttta tattcaaggt ttggtagtga gtatataggt aatgccaata tgttttcttt
    76021 taataatatt gatggtatgt gcccacactg tcatgggctt ggaaaaaagc tagttcctaa
    76081 tatgaaccaa attcttgata tgaataaatc attaaatgaa ggtgctatat tgctttcagg
    76141 gtttggagtg ggttcttggc attggaatat attcgctgaa tcaggatttt ttgatattaa
    76201 taagaggata tgtgattatt cagaagtaga attggaaaag tttttgcatg gtaaagcaga
    76261 aaagattaag atagaaaatg ctggtcaaac taacatgaca tatgagggat taatggttaa
    76321 atttaatcgc ctatacttaa gtagagaggg agaaatatct gaagctacta agaaaaaatt
    76381 gagtaaactt cttatagaag atagatgtcc tatatgtgat ggaagaagac ttaatgaaag
    76441 agtatatagg tctttaatta atggttataa tatagcagat ttaactagta tgcaaattga
    76501 tgaattggct gaagttatta aaagtataga tgagccagaa gcacaacctt taattaaagg
    76561 aataatagaa aagttaaaca gtatcataga tataggtctt ggatatttaa cactagatag
    76621 agagacatct tctctatcag gaggggaatc tcagcgtata aagatggtta agtatttaaa
    76681 tagtaatctt gttgatttaa tgtatatttt tgatgaacca agtgtaggac ttcatccaaa
    76741 agatgtgtat aaattaaata atcttttaaa aaaattgcgt gataaaggga atacaattat
    76801 agttgttgaa catgacccag atgttattaa gattgcagac catattgtag atgtaggacc
    76861 aaaggcaggt aagtatggtg gagaagttgt gtatgaaggc agttatgaaa atctacttac
    76921 aagtggtact ttgacaggga atgctttaag taaatttctt cctattaaag aaagtgtaag
    76981 agaacatagt ggatatttag aagttaaaaa ttgtaataaa aacaatttaa aaaatgtatc
    77041 tattaagata cctaaaggtg tattgacttt agttactgga gtagcaggag caggtaaaag
    77101 tacattgatt aaggatgaat ttttaaagca aaatcctagt gctgtactta tagaccaaag
    77161 ccctgtttca gcaaattcaa ggtcgagttt ggcaacatat agtggaatta tgaacaacat
    77221 aagaagcata ttttcaaaaa caaatggcgt aaatgcttct ttattcagtt caaattcaga
    77281 aggagcttgt gataactgta agggttctgg aatagtagaa atgaatcttg cttttatgga
    77341 gagtataaag agtacctgca atatttgtga aggtaaaaaa tttaaaaaag aagttttaga
    77401 atataggttt caagggaaga atataattga agttcttgaa atgtctgttt tagaggcaat
    77461 tgagtttttt aatttaaaac agattaaaac gaaattacaa tgtattgaaa aaatgggtat
    77521 tggatacctt actttaggac aaactcttga tactttgtct ggaggagagt gtcaaagatt
    77581 aaagcttgct agtgaattaa ataaggaaag ttcagtgtat atattagatg aaccaacaac
    77641 aggtcttcat atggctgata ttgagaattt tataagtata attgaagaga ttgtagataa
    77701 tggaaatacg gtcataataa ttgaacacaa tatagatgta attaaaagag ctgattggat
    77761 tattgagctg ggacctgaag gaggaacaaa aggcgggaga gtaatatttg aaggtattcc
    77821 aaaacaatta tgtaacaata aaatatcatt aacagcaaaa tatatagtat aataaataaa
    77881 atataataaa attataatga tattttaata aatataatgg gtatataaaa tgataattaa
    77941 acttaacagt aataaataat gtgagaaata ttcaaattta attaaataaa gtgtcagaaa
    78001 tttgtttaaa ttttagtatt ttaacggttc tgaccttttt tcttattttt atggagaata
    78061 tcgaggatgg agtctctaat agttactttt ttgtgtctac ttgcaagttt gattaaaaaa
    78121 tggctataca cacttgtgac ttcagtcatg ggaggttcag attataatct taatatataa
    78181 tttgtgaaat aatttgatga cgatttgctg atgtataaac aataaagatt aactacatta
    78241 aaatttaaat cttgttaagt aaaacttata aaaggagaga gatggatgat aaatgatatt
    78301 ctaaccttat tatctgaaag aagtgatttt tttataaagc tatccataga acatttgatg
    78361 atttctatta tttctataat aattgcgatt gttttgggtg gtataattgg tattattgta
    78421 agtgaatttc ataattcttc taaacctata ttgggaacta tcaattttct atacaccatt
    78481 ccatctattt ctatgctagg atttctgata ccattttccg gaattggaaa tactactgct
    78541 gttattgcac ttaccattta tgcattattg ccaatggtta gaaatacata tactggaatt
    78601 actaatgtgg ataaaaatat tcttgaagca gctaggggaa tgggaagtac agattttcag
    78661 atattgtata aaataaaact tccgttagcc ctacctgtta ttatgtctgg tattagaaat
    78721 atggtgatta tgacaattgc attagctggt atcgcttcat ttataggtgc tggaggccta
    78781 ggtgtagcca tatatagagg aatcacgaca aataacacaa taatgacaat tactggaagt
    78841 atacttattg ctctattagc tttaatattt gattttattt tagggctggt agaaaaattt
    78901 tttcaacgaa aaagaaaaaa gaaaaatagg aaaaaagttt ttgccattct aggaagcctt
    78961 attcttatag taattatctt tacgtcttat ttatttaatc cttcaaagac tcaaactatt
    79021 catattgcta ctaaacctat gactgaacaa tatattcttg gtgagatgtt ggatatttta
    79081 attgaaaaaa acacaggtct aaacgtggaa attacacaag gtgtaggagg gggaacatct
    79141 aatatccagc cagctatgga gaatggagaa tttgacattt atccagagta tacaggtaca
    79201 ggctggaata tggtacttaa gaaaaatgaa ttatatactg aaagtatgtt tagtaaacta
    79261 cagtcggaat acaaaactaa acttaaaatg caatggactg gtatgtatgg tttttctaat
    79321 agctatgcat tagcagttag aaaagaagtt gcagataaat acaatttaaa aaatataacg
    79381 gacttaaaag atgtatcttc taaattgaca tttggagctg aatatgactt ttatgagaga
    79441 gaggatggat atactccatt gtgtaataca tatggactga actttaaaga tacagttgat
    79501 ttagatattg gattaaaata ccaagctatc aatgaaggta agattgacgt aatgcctata
    79561 tttacaactg atggtcagta tagtgtttca gatgttgtag ttctaaaaga tgataaaaat
    79621 ttctacccat cttatcaatg tggaaatgtt gttcgtttgg aagtattaga ggaaaatcca
    79681 gaactatcaa aggtatttaa gatggttgga gatattttga ctgataaaga aatggctaaa
    79741 atgaattatg acgtagaaaa caacaattta gaacctagag aagttgctcg tgagtttctg
    79801 aataagaaag gtcttttata aattggagga aatataatga cacctattat acaatttaaa
    79861 aatattaaaa aacaatataa tgataaaact ataatagata atcttaattt agatatagaa
    79921 aaaggagagt ttttgactgt aattggttcg tctggttctg gtaagacaac actcttaaaa
    79981 atgattaatg gtctgatttt gccagatgga ggaaatattt tgataaacca aacagatatc
    80041 aaaaacgagg acttaattaa attaagaaga agaataggat attgtgtaca gggaagtgtt
    80101 ctttttcctc atatgactgt tgaagaaaat atttcatatg taccaaatct cctaagtaaa
    80161 aagaataaat tagaagtaaa aagtgctgta aacaagtgga tggaaatagt gggattgcca
    80221 aatgatatga aagtgcgtta cccatcagaa ttgtcaggtg gtcagcaaca acgtgtaggg
    80281 attgcaagag ctttagcttc ttctccagaa attttattaa tggatgaacc ttttggtgca
    80341 gttgatgaga ttacacgaaa gcaattacaa aaagagataa aagaaattca taaaaaaaca
    80401 ggagttacga ttatctttat tacgcatgat atttatgaag ctttgatttt gggaacaaag
    80461 actttggtat taaatcatgg agttgttcaa cagtatgata ctcctgagaa tattttaaat
    80521 actcctgcta accaatttgt agaccagtta ttgaatataa gaaaatctat aatagatgat
    80581 gataatttaa aagaataaat ttaaatttaa aatcaaattg ttgtgataaa aactattgat
    80641 ttagagctaa cttcaagttg tatacttgaa gtggaaaagt tagattaagg tatagaaggg
    80701 catttagcag ttggctgtag acgaggtaac tgctgaaggt gctttcaata aatggctaga
    80761 acctgtatct gttgaagatt ataataaatt gaaataagaa gctcaatata cagagtagat
    80821 aggcacttca aatagaagtg tcttttgtgt gccataaaat aaatcaaaat attagcaaag
    80881 aatgtgaaaa acaaaataaa ataatatgct atctttaaaa taggagggat gctatatgga
    80941 taacaatttg attaccattg aaaaaacttt agattatata gaaaaacatc ttttagatga
    81001 gatgttagat ttaaatgtaa tttctaaaga gataggctat tcaaaatacc atttacatag
    81061 aatgtttaca tcagttgtcg gatttagtgt acataattat atacaaagac gtagacttac
    81121 tgaagcagcg agaatgctaa tttttacaga aaaaccaatt attgagattg ctttaatctc
    81181 ggggtatgat acacaacgct ctttttcaag agggtttaaa aaaatgttta aacgtagtcc
    81241 taattttttt agaagacatc aagatttttt accactacaa ttaaaatttg atattcataa
    81301 tagaaaaaaa ttacgtggag atatggtttt agatgttaaa aaagttaatt gtgcagatat
    81361 aaatattgtt ggctattctg gtaaagtaag aaaaggattt catattattg gaaaatgctg
    81421 gagggatttg cataaaaata aagagatgat agaaaataag gtagatttag gttttttaat
    81481 tggagttagt gattatagca attttaaaga gattgagaat actcctacat ttacatacat
    81541 tgcaggtgct caagtagcta cttttggcaa attacctaat ggaatggaaa aattcgtatt
    81601 accgaaaagt aattatattg tttttacttt tattgggaaa aatgaggata gtatgcaaaa
    81661 tgttgtagaa tatatctatc aagaatggtt ccctaattca agttgccagt ttaatgaaaa
    81721 taatttatat gactttgtaa aatatggaga aaaaactgat gagaatggtt tgagtgaaat
    81781 tcagttttgg gttccaatca tttaaaagaa ggtattatgt ataaagtaga tggatttata
    81841 taggcaaagt tttacagcag tatgtattta taaataattt atagtttgta ggaaagaaat
    81901 aattttacta taagattatg ataaaataca caatactatg acaaaatagt gttaaataat
    81961 agatttaatt ttgcatagga aaagttctat aatggtgtgt attcataaat aatttataat
    82021 ctgtaggaaa gaaatagttt tactataaga ttatgataaa atacacaata ctatgataaa
    82081 atagtactaa ataatagatt taattttgca aaggataagg tgttttaata aaaatgaatg
    82141 tagaaaacga attacttaaa aacctagata gattgcatac aacagagtta ggcgttgtaa
    82201 gaattaagaa aaatctttct ttggagacaa atgatgtagt gaactggtgt aaaactaaaa
    82261 tagaatctcc aaatgccatt attaatagaa agggaaaaaa ctggtatata agtgtatatg
    82321 attgtattat aacagtaaac gctcacagtt atacaattat tacagctcat aaagaaaaga
    82381 aatgaattgc aaaatacaaa ggtcaaaagc attttccact gtttgtagta cctatgaaga
    82441 agtatataaa ataatattac ttttgaataa taatttaaat tttggaggtt gaaaaaatga
    82501 atgatactgt aaaagaaaaa ttggcagagt cactaacttc tgatactact gatattttac
    82561 cttatttgcc ttatttatta caagattttt gggaattagg aagttcacca gaacaaatgt
    82621 tacaattatt tagaaagcat atacctttta atgaggatac aaaagttttg gatttagctt
    82681 gtggaaaagg tgctgtatct gtgaagcttg caaaagagtt gaatatacat atcaaaggta
    82741 ttgatttgat acctgaattt attaattatg ctagaagaaa ggctattgaa tataaggttg
    82801 atgctttgtg tgattttgaa atgaatgatg ctaatagttc tgtaaaaatt gagcatgatt
    82861 atgattgtgt gatttttgga gctgtagggg atattttagg taattataaa gaaactataa
    82921 gtaagctatt acctacaata aaaagtaagg ggttcatttt aattgatgat gcatatgtag
    82981 tagataaatc tacaaatgaa cagcttaatt ttgagagggt gtatcccact tacaatgagt
    83041 ggtgtatatt gttcaaagaa ttaggtctga agctaattga atgtatacca tgtttagaac
    83101 ttgaaaatga tgttgaagag gaaatgaatt ggattataac tcgtgcaaat gagctaatta
    83161 aaaaatatcc ttctcaaaaa gatatgtttg aacaatatgt tattagccaa aaaaatgaat
    83221 atactgattt acagcaggac cttgttggag caacttggat tttacaaaaa gaataagata
    83281 aatattagac tagataatca atgttatagt gaattatccc atgtctagtg aatataaata
    83341 acataaaaaa ccgtcaagat gaatagttta ttcgtgcttg acggttttta gtatttgttg
    83401 aagtaaaatt ttatttcttt agtatatcac ttttagtcaa tccatttgat ttagcttgag
    83461 tattccattg atgattcccc ataagtttat ataggaatct agggaagtta ggtgaaataa
    83521 aaatagtact tttgttggaa tcatctatat gtatattatc actaagtata ttttttgaaa
    83581 gttcttttaa tgcaattcct aaatcttttt taggtccttt acccaaaggt acggattcta
    83641 gtgaaccaaa catctcccca gctccaattc caataccttg aacccatgta aagttgattt
    83701 ttttacacca atgctctatc atttgaattg ccaaatgatt atgttcacct tcattgaatc
    83761 cacagttaac tattgcatac actggaatag gttttttatt ttgtgttttt aaaaattttt
    83821 cacatttctc taaaaaatga agtaaatgag atggaatacc atctacataa agaggagatg
    83881 cgattattaa tctatcacaa ttaagtatgg cattaagagc gtcaggatac ttagatgtgc
    83941 tatctacttt aaatgtaaaa actttattat cattttgaat aagttgtttt aattcagata
    84001 aaaaatactg tgaattattt ttatttactt ttggactacc atttatcatt actatattca
    84061 tatggattca cctcttatat cttgtatatt ttcatagaaa caaacagagt gttcttttat
    84121 attgaaattt atagcatttc catttactaa tttcgtagca gtttcttttt cagcttctgt
    84181 aatacaatct ccatagaata tagcttttaa atttatctgt ttatcatatc tgcttttatg
    84241 acgcatcata ttatctttta ttacaaagta tggaagaata taattaatgc ttttatcaag
    84301 tacgtttttg acaaaagggc taaaccctcc gtaacagcat ctgcttatta taataattcc
    84361 atcagagtca tttataagtt tacccatgtt gctgtaataa tcttttacaa cacattcaga
    84421 aggagtttta atccagcaac caaaacaacc aatacatttg tggatttctt ttgtgtttgg
    84481 aagtattttt atattgtcat caagtttggg taataacttt tctaattctt tgtcagttaa
    84541 atcatgtatt aaaagcctca taaagtccat ctccttttat tatgtatgtt tacttctaaa
    84601 aattatatct tatagatttt tcagtaaatc tttacaccaa ttaataacaa aattataata
    84661 gtcaactcca taaatcattg ttgcatacat atatgtatat tggtcaacgc aatgattttc
    84721 ttctgcatca tttttttgtt tacttaattt atttagaagt aattctactt cagttattaa
    84781 catttttaag tttgtttcaa ttatttcttt gggtagatac ttgtaaaaga atatattaac
    84841 aaggtggtct tgctttgttt tagaaaaatt tataggtttc tttaaccatt caagaaatac
    84901 ttctttacca gtattagtta tggaatataa tttttttaat ttgctaccat ctataacttc
    84961 gtgatagtgt atatatcctt ttgtttctaa tcttttaagt gcaggataga tacttccaaa
    85021 gctggcgtca aaaaagtacg aggtactttc tgacattatt tgttttaagt cgtatccact
    85081 taattctttt tccattaaaa atcctaaaat aatgtattct aacatattac ctcctggtat
    85141 caattagata tatatcgatt cgatatattt attattacag ataataaatc ttacgtcaag
    85201 atgcttttta agataagcta aaaagaatta ggagttattg ataaatatgc aaaaaaatta
    85261 atataaaagg taattaaata tcaatgaaga tttaaaaata gttaaatcaa agtaagagtc
    85321 taatatataa aatttatagt aactttatgg tttaaatata aacttgcgtg ctattgacaa
    85381 agtataaaat tagcagtaaa ataattgcat gagcaaatag attattgcga acgcaaaaaa
    85441 ataaggacaa tagatattaa aggagagaat atgagagagc tattaaaatg ggtttccatt
    85501 ataaatagat acaatacaaa ttatattgac aggaaattgg cggatattgg aatcaataat
    85561 agccaatatt tttatgtatt acacatatgt aataatccag gtattacaca ggacactata
    85621 tttgagaaaa ttcttgtgaa tcctagtaat ataacaagag ctttggcaaa tttagaaaaa
    85681 gaaggcttta taacaagaga accaggtgta aaggataaaa gaacatggca tttatatcct
    85741 acagaaaaat ctttaggatg ttatgatgaa atactaaaaa taacaaatgg gtatgttgag
    85801 gagttgttga gttcatttga gaaagaagag caagagttgt ttatgtcaat gttaaagaaa
    85861 gttgcatttt tggctattga tatgaatgaa gaagcaaaat tggaggcgaa ggaaaatgga
    85921 agaaaaatat aaggagccat tggaatatga aaaggtttca aagttattaa ctaagtacgc
    85981 aattcctagt attatagcaa tgttagtaag tgctttatat aacattgttg accaaatatt
    86041 tattgggcaa ggtgttggtg tattgggtaa tgctgctaca aatgtcactt ttccactaac
    86101 aacaatatgt actgcaattg cattattgtt aggaattgga ggagcgtcta agtgttcatt
    86161 ggaattaggt gctaaaaatt cagaaaaagc tacaaaagca gcaggaaatt ctatatgctt
    86221 gatggctgtt tttggaataa gtttatttat agtagtatca atatttttaa caccactatt
    86281 aaaattcttt ggctctacat cagaaatact accttatgca cacacatata caaaaattac
    86341 atcaattgga ttaccatttc ttataatgtc cactggaatg agtaagttga tacttgcaga
    86401 tgggagacca aaagcttcta tgttttgtat gttaatagga gcagttatta atacaatttt
    86461 gaatccatta ttcatttttg tttttaatat gggaattgct gggtctgctt tagcaactgt
    86521 tattgggcaa cttatatctt ttggaataag tgttcattat ataaagaatt ttcaacatat
    86581 taaattacat aagaaaagtt ttaaattaga tagtataatt tataaacata tatttgcgct
    86641 aggttcaagc tcatgtttta atcaattagc aatgactgta acacagatag ttatgaataa
    86701 tacattggca tattatgggg ctaggtcagt ttatggaagt gagattccac ttgcttgtgt
    86761 cggtatcatt attaaagtaa atatgatttt tatatctata attattggta tatcacaagg
    86821 tatgcaacca attatagggt ataattatgg ggctgaaaag tataatcgtg taaaagaagc
    86881 atataagttt gcagtgggaa gtgcaactat tatatctgtt attgcattct tatgtttcca
    86941 attcttccca agacaaatta cgtctatatt tggtaacgga aatgagactt attttatatt
    87001 tgcagaacat tattttagaa ctttcttgtt cttaacattt ataaatggtg ttcaaatagt
    87061 atcatcaact ttctttacat caattgggaa atcagtgttg ggacttttta cttctttgac
    87121 tcgtcaaatt ttatttttaa ttccattgat agtaatttta ccaatgttta tgggaattga
    87181 tggagtaatg tttgcaggac caatagcaga tgcagcagcg gcaatggtat gtatatactt
    87241 tgcagttcat gaaatgaaat cattgactat aaagcaaaat aatttgatga gtaaccataa
    87301 taagattgca gaggtataag acaatattta agaagtatag aaaattaatt taaaaaatat
    87361 aataaattaa tttaggaagt gtagaaaatt aatctaaaga agtataataa actaatttag
    87421 gaagtataga aaattaatct aaagaagtgt aataaactaa tttaggaagt atagaaaatt
    87481 aatttaaaga agtataataa actaatttaa gaaatataga aaattaattt aaagaaatac
    87541 aatacattaa tttttaagta acattaaatt aatgtaagta aaataatgtt catatgaata
    87601 tttaaaggtg cattttctga agctaagtat atgttgtaga gtgttatgtc tctctatcct
    87661 gtgaagttta atagctcaag aaaatgcact atttatgatg attattttgt tttatttcca
    87721 attttggaaa taactattct aattaaatct aaaattatac cataaataag aaaagaaagt
    87781 atagatgcta tgtaccaata aatcgaaatt gaccctgtaa ttgttctaca tgggatttgc
    87841 atacctgaat ccataaaaac aaaaaaacta tcaactctgg aaataataga caaaatagga
    87901 tttaaaccta ttagaacaat actttttgag tcttgaccaa tttgatgcat ataaatctca
    87961 aataatgcaa ttaaaaaaaa ccaagatgta aaagatttaa taattttttt catcaaaata
    88021 cctcacataa tataaattct gtttgcacta tttgcttact acaactattt atctccattc
    88081 agtcacatca cttaattgta atctaggtct tcttgatggt tcttcatcag gataacctaa
    88141 agatattgct gccactaatt gactatctgt atttaaccat tcacataatt cacgatatgc
    88201 aaagtataca tcacaaatcc aaagactacc tagacctaat tccacagctg taagcgacat
    88261 attctgaatt gcagctccaa ttgattgcat atttgccatt tcatagaatc gttcttcagg
    88321 ggatagcttt tctaaaggtg atttacctaa tatatttaaa ataaaaattg ttactggagc
    88381 ttgtttcatg atttcaactg tgtaatttgc accagcgata tgttgacgac ttcctggaag
    88441 aagcccatta tcattaattt cattttgaat acctttgctc atggctttaa gcatagattc
    88501 tttttccttt tcagtgatga caacaaaacg ccatggttgc ctgtttttag atgaaggtgc
    88561 atttattcca gcttcaatta ttttctctat agtttcatgt gaaatgcttt gatttttata
    88621 ttttctgata cttcgtcttt ttgatataga atcacttatc attttaagta acctccgttt
    88681 attttttgga aaaatctatt taatttttat tttctatttt aattatttta gcattaatca
    88741 gaaaaaaagt cattgatttt agtatacaat tattaatgat tatattaaga attgtatcaa
    88801 aaagtatgtg attatactaa gggattatat taaacattat atttaaaatt gtatgaaagg
    88861 ttgtatttaa tattatattg agagatatat atattaggat ttatatatat tcagatttat
    88921 tattatattg agtcttatat taaattaagg actataattt gaaaataagc tataaaaact
    88981 caatattgtt ttgttcaaag ataaaaaaag aatactttag gtgattttta ttaaaaatta
    89041 agagtgataa gattatatac tttataaatg taaatatgac ggataaaaat gataaatata
    89101 ataatatata tatttacatt aggagttttc tatactataa ttatttaaaa ctaaatataa
    89161 atgttggaat tatttaggac ttgaaattgt ctaaaaataa atataagtga tgaagaggtg
    89221 atgtgatgag attagatatg gatagtatgt tatatgtact aatttatatg acattattgg
    89281 tatctatcat tggaagtata ttttattttt gtaaagacct cttaaatcat aaaattaagt
    89341 atgttttaat aagagacata tttgtaaata gaattacata ttctgaagaa cggttgccta
    89401 aacagtatat agtttttcag aaatatgata tttggaggta ttgtagtttg ttttaatttg
    89461 aaatgaatct attataaatt ctaaagttta aaaataaaaa ggagagaata aaatggattt
    89521 catttcaagt atattgcaag gattattaag tatattattt aattttacag gtgattttgg
    89581 aatttctatt gtacttataa ctttaatagt taaattagta cttatgccac tatcattaaa
    89641 acaaagattt tctgtaaaaa aacagcaaga attagctgaa aaaatggaac atataaaaga
    89701 aaagtataag aatgatacta aagaattgga aaagcaaata caagtaagtt ctgtagaaag
    89761 tatgaagagt atgctgggat gtcttatagt tttggttcaa atgccagtag tatatgcttt
    89821 atatcatgta tgtttagata tgacaaagga atttacaaca attataattc catggattgc
    89881 taatttaggt acatttgata atttgtttat attaccttgt atatatacat taattatgtt
    89941 agcttcaaat ttagtgaatt atataccata tttaaaaata aattctcaag taaagtttaa
    90001 caaacaaatg gctgtggtga ctaccataac aagtcttata ctaactgtta gaactccagt
    90061 agccataggt ctgtacttta taacaagtgc aatttattca ttaattgaag atatttgttt
    90121 tagaatatat tttaatcgaa aaaatagaat agtgacaaaa taatataatt attattagaa
    90181 atattttagc ctgctaacat agaaaaagtt agtaggctat ttttatctat gatatcaatt
    90241 ccattaagaa tagtctaaaa aatactatca aaatgctata aaaaatacta tcaaaatact
    90301 ataaaaaaat agttgaaaaa taaataaatt aatataaact aaaataaagc ctacaaaaaa
    90361 gaggtgataa atagaaatgg ctaaaatact aattgtagaa gatgaaaaaa ggatgcaaag
    90421 tattattgta gaatatatgc aaaagggagg atatacttgt ataactgctg atgatggagt
    90481 cgaggcactt acaatattaa agagcaacaa tatagattta atgatattgg atattatgat
    90541 gccgtattta gatggatttt cagtgtgtag agtttcacgt gaaatgacta atatacctat
    90601 tattatattg acagctaaag gtgaagagga ggacaaatta aagggttatg aatatggcgc
    90661 agatgattat ataacaaaac catttagccc caaagtactt ttagcaaaag ttaatgcctt
    90721 gttacgtaga tacactactg atattcccaa aaattcattg agtttaggaa agatttttat
    90781 tatggtagca tcaaggcaag tgtatgtaga agataaattg attgatttaa catataaaga
    90841 atttgaatta ttgcgtttat ttatggaaaa ccctaatcaa gttttttcca gagagaaact
    90901 tttaaattgt atatggggat atgattttga aggaaacaca cgaactgtag atacacatat
    90961 aaaaacctta cgcaaaaagc ttggtagtga aggacaccat atagttacat taattcgttc
    91021 aggatataag tttgaggtta aggaatgaat agtttaagaa agattataga aaaactgaaa
    91081 aatgtagata tttcaaattg gattaaacaa aattttggac tatattcagt tagaaaaaaa
    91141 gtgtttttac tttctaaatt atcaggagcg ttaattatat tattttatct ggttgttgaa
    91201 gaattttcga taaactctaa attagaattt tggatttggt ttataatact ggttatattt
    91261 attatgagta ttgatttctt attgggaaaa tttatttcag aaccaatcac atctataaat
    91321 aaatctgcaa aaagtatgtc ccaacttgat ttttctaatc catgtactgt aaatactaat
    91381 gatgaatttg gagaactttc taggagcctg aatacaatgt ctacaaatct acaacaggca
    91441 ttatcagacc tagaaagtgc aaatattcaa cttgaaaagg atgtaaataa ggaaagaatg
    91501 ctattggaac aaagaaagga gttggtagat acaatttcac atgaaatgaa gactccactt
    91561 ggcattatac gtgcgtatac agaggggctt atggatgaag ttgatgaaga aaaaaagaaa
    91621 aattatatga atgttataat agaagaaact gatagaatga acaatatgat tgtatcatta
    91681 ttagacttat ctgcattgga agcaggagtt tctaaactta acccagagcg ttttgatttt
    91741 atagagtttg ttgaaactgt ggcaggtcgt cttttaattg atataccaga tgccaatttt
    91801 tattttacat atgatttgcc agagtatgaa gtttttgtag tggcagataa aatgagaatg
    91861 gaacaagtag tagagaatct agttattaat gcaaagaagc atgttgtata taatggtaat
    91921 ttagatttat cgattacatg tgaaaatggc ttgcttttat ttgaaattta taatgatggt
    91981 aggtttatag agcaagatga gatttcaaag atttggtcta agttttatcg tagtgttcaa
    92041 tctcagcgta caggaggttc aggtctaggg cttgcaattg tttcacaaat acttacaatg
    92101 caagggttag aatatggagt gaataatcgt gatagaggag tagagtttta ttttatgatt
    92161 ccaattgatg aataatttag tattaattta taaattataa gtatctgatg taaaatattt
    92221 ttctttgtat atgtaagcat ttaaagagaa taaaataaaa aaacttaatg aaaaaagctt
    92281 aatgaaaaag tctaataaaa agcttaatga aaagtcttgt ttttctgatg aaaacaagat
    92341 tttttattaa gctttttatt atttcacttc gatttcacaa gagagacact ctgatttcac
    92401 caaatagaaa taaaataggt taaataaatt aaaaaataga agcgtaatta aataaggtta
    92461 caagggggag tacttatgaa atggtataca tggttgacta ttatattgat aatattgctt
    92521 tctattccgc ttaaaattaa atttataaaa tggtgggata gacgacaaaa aaatgataaa
    92581 ggaggttatg atagatgata aaagtaggag agttaaaatt ttcttatgga aaagataaac
    92641 agatattgca tggacttaat tttgaagtaa aagaaggaga aatctttgga ttccttggac
    92701 ctaatggttc aggaaaatcc acaacacaga aaatcttaaa tggtgtttta aaaggttaca
    92761 atggtcacgt atcccttttt ggtaaggaag ttaaagcata cacagaatct ttatatcaaa
    92821 agattggtgt tttatttgaa tttccttatt tatataccaa tttaagtgca attgataatt
    92881 tagaatattt ttcgtctttt tatcctaaaa atcaaaggag agatatatat gaactcttag
    92941 atttgttaga gtttaagaaa gagtttataa ataagcctgt atcatcctac tcaaaaggta
    93001 tgaagcaacg tattagtatg gcaagagcat tggtaagtaa tccaaagttg ttatttttag
    93061 atgagcctac tagtggactt gacccatctg gagctgtact atttcgtaag attattgaag
    93121 aagaacgaaa aaaaggaaca actatctttt tgactactca taatatgcta gatgcagatt
    93181 taatgtgtaa caatgtggct tttattgcag atggaaagat tatggtaata gataaaccca
    93241 aaaatttaaa aatgaaaaat agcaataata aagttgaagt ggaatttgta tataatggaa
    93301 atcgagatat tgaaattgta gatatacaag agttagaatc tggaataact tttaaatatg
    93361 atgaaatctt aagtgtacat tcaaaagaac ctacactaga agaagttttt attaaataca
    93421 caggaaggat gttagtgtaa tgtactctaa attttttacc ttagtaaaaa aagatttttg
    93481 gatgatgatt tatggtaaat tttttgtgct gacacttggc tctctcatac tttattcgtg
    93541 ttatattaat tttggttatg taaagtttat ggatgaagat agttatcaca ataatgtata
    93601 tctatataat ccagagaata taagcatgag tgcatctcca ttaattaatc aagtttcttc
    93661 tataggtgaa ttaaaagcaa aacttgatga agatacaagt gcagtttgta ttgatatgag
    93721 ttccagtaag ccgaaagtaa ttttacatga aagtattaaa ggagttgacg attatagagc
    93781 tgactatgca ttgtcattat tatcatcaga aaaagaccac aatagcaaaa tatcagacaa
    93841 caatgcaata attcaaatta atgataagga tacatctgag ataaaacaaa gaaaagacat
    93901 gacttgtgag attttattct ttgaaattgt agctattgga tttttaggga ttgcctcttt
    93961 attatttaaa gaaaagcaga tgggagtaat gcgtattact ggtattttac ctgtaaaaag
    94021 aagtcttttt atattatcaa agatatttgc ttttttgata tgtgacctat gttttacagt
    94081 tcttttagta gtatttaata ttggattttt tgaaggaata aaaatacttc cacaagtatt
    94141 agttcaagct agtattttat caattattat gtctttgatt ggaataggat gctcaatgtt
    94201 attgagagat tttaagcaat tttctcttat atatcttgtg gttgctgtat tcataactac
    94261 acctatattt ctatctgcaa atacatcttt tgaaatagat tggattaaat atcatccctt
    94321 ctatcatgtt tatagtcagc ttaaaaatgc gtttttcatg aatttttcaa aagaattagt
    94381 ttattttgta gtgtgttctt tgacaataat agttctattt ttacttgtaa aatatatttt
    94441 taataaagag ttggttaggg agggataatc ttgataggat tacgttacca gttaaagagt
    94501 ataaaaaaag ataaaatgtg tataatttcc ttctttttac cagttgttat ggcgatttta
    94561 ataaatttta tgggaacaat tgatatatct tcattaggag agatacgttt tggtatagtg
    94621 aaggatacac ttcctgtaca aacagagcag tggttgaaga agtatggtat ggtaagtgta
    94681 tatgacacaa aaatgcattt aatacgtgaa attaaggata ttaaaacaga cacaattgga
    94741 gttgttagag atggtaaagg gataaaaact gtgctttatg gaaatgagat taatgctata
    94801 aaaaatgttg gaaagacatt gccagagatg tttagactaa agggtgattt aaaagatgtt
    94861 gaggttacaa tattgcctaa agatagtatt ttaaaagagt ttcaaaatgt ttttattgcc
    94921 atgattttaa ttactgctat gtttatggga tgcaccttta atgcaatgaa tattatatct
    94981 gaaaaagaag atggaatatc atttataaat gaagttttgc cacagagtag aagtcagtat
    95041 attatacaaa aagtattttt gggtctttta tgtgggtgtt tatcttcaat gataactgta
    95101 tttatatgtt tggatatttc aatattagat atgataatga tgttgttact cgttgtattt
    95161 tcagcattta tttcatcact tataggttta tttattggaa agttgtcaga aggtcttatg
    95221 gtaggaattg tttatattaa aatagtaatg attttattta taggtactcc tttgttaata
    95281 tatcttctag gggttaatac cagtggtata gggaatttat actatataat gccttcagtt
    95341 gctacattta atggtattat ggagattatt aatggtaatg tcattattat caaagatatt
    95401 gtaattttgg ctgtacattg tgtagtatgg tttatgatat atattatttt agataaaaaa
    95461 agaaagttat tttttagtag ataactcagt ataattataa ttgggacaat ttaataggtg
    95521 atttaatata ctttgtatag tgtaatttat gtagtgcaat ttgtatactt taatttatgt
    95581 agtgtaatag ttagttttat tttataatta ttcaatataa tttagtaaga agttcagtac
    95641 aattagagct acttagtgga aaacttaata ggtacttaaa ctatataaat actttatttt
    95701 cctccatttg tactataaat ttaatttatg atataaatgg aggtattatt atatgatttg
    95761 ataaatttca tcattataac ctacaagtaa aggtattatt atataaagtt aataaagata
    95821 gtatcaaaat attatttgct ataaagagag gggctcaaaa taaagataaa cctatttttc
    95881 aatgttgaaa tgataaaata tatttgattt catataaaaa attttcttca taaattaaaa
    95941 agtccatttt aagccccctc atttttaacc agataaatcg agttaaacta tttaaatata
    96001 ttactcggat tcatttgact tagatattcc ttgcttgtaa aattgttttg aataggggat
    96061 agccaaagca aaaaataaaa gtataatccc tgctatgatt attaaattat taatagaaat
    96121 tacatctgcc attggtccga aaatcatcat accaagagga ataaaaccag tatatataat
    96181 aataggtaag ctaagaactc gacctagcat ttgtggtgct acatgctctt gcaacatagt
    96241 catagctgat gcttgaatga ttggaattga aaaattcgta aaaaacataa atataaaaaa
    96301 ttgccaagct tgtgttacaa gacctagaat aattgaaaaa atagcatagg ataatattgc
    96361 tagaaaaaag gtcttatttc tatttttaaa accaccaaaa actcctataa tcaatccacc
    96421 taaaaccata cctaaaaatc caatcatttc aataatagac aggtatatat aacccttgcc
    96481 aaatgttcgt tcaataagaa gtcctataag aaatcctgat ggaacacaaa gaagcatgaa
    96541 tgctccataa gtaaaaagca cttttctaat gaacttatct gaaaaacagt actttatccc
    96601 tgataccata tctgcaaaaa atgagacttt ttcagtttgt tttggtatat catgtttagg
    96661 aattttgatg aatatcaata atacaatagc aataattgca gtaaatacat caattaaaag
    96721 aacttgattt attttattac caaatccaag tattgcagca gctacaatag gaactataaa
    96781 ttgtactata gattgtaggc tactatttat accattaaaa cgcattaaat gttcttctgg
    96841 tacaagttga ggaatcattg cgtttacagc aggtgtttgt acaccacttc ctagtgaacg
    96901 tataacagat attactgata tggctattaa ttcacttgtt gtgccatttg atgacatcat
    96961 aaatagaatt agaactaatg tagatatagc aattgttgaa tctgatacaa ttatgagtac
    97021 ctttcgattg tagtagtctg cccatacacc agcaaaaaaa gaaattatca tttgaggtat
    97081 aaaggagcat acagttaaaa ctgttaccca tacacctgat gatgtctgaa gtgtgacata
    97141 ccatatcatt gccatttgta caagtgatga gccaaataag gaaatatatt gacttgctaa
    97201 aaaaagaatg acttttttct tccatgtaga attagtattt ttgttttcca tcctattcct
    97261 cctttgattt gtgtgttgaa tttttcttgc tcttaaggat aacacacaaa tcaaagtctg
    97321 gagttagagt ggagggctag gaaaattgtt ttttcataat ttgaagatga gatttcatgg
    97381 tttttgcatt atgttcagct tctttcaatg aagttatcag tttgtcacac actgagataa
    97441 tttcgtcatc atcttttgga gtgtcaagga cagttttaat attagtatta ggattagaag
    97501 ataaagcatt taacattcgt aaaatagctg aaagagaata gtttgcacaa cgaagtgcgc
    97561 ttataatttt aagtcgtttt atatcttcat cagtatatac acgataacca ttttgttttc
    97621 tttttacttt taacaaacca ttcatttccc aatttcttaa agtatctatt gtaacgttta
    97681 agtgttctgc agtttctttt ctagttaaaa agagtttatt tgtttctgga gtatttccat
    97741 ttaaaatctg tgcaacaata gtaagtgctt cctcggcatt agatttttct atttctaatt
    97801 gttgcaagta ttgatttaca agactaatag ccttatcaaa gtccctattc gctgatgttc
    97861 ttacaatctc aagggcatct tttcttaatc ccctttgtac cacttcaatt ttcaaggctg
    97921 tacgagcaaa tctaaattgt tctatatgaa aatcattaaa gatacgataa ccattggtat
    97981 tacgcttagg tttaggtatt aagtttagtt cttcatataa acgtactgta ttaggatgta
    98041 caccaattaa atctgctacc tctgatgtcg tgtaagtgtc cattagtatt caactccttt
    98101 tagatatata gtattagtca taataacacc aaacaaaagt ctggtgttat aatggagggt
    98161 ttggttatct aagagtaatt aatttatgaa agagtaatta atctattata gaagtaagta
    98221 tatatttttc aataaactcc catctatcac gaggtttaaa cactatttta gatggtatgg
    98281 ctattactaa gtcatattgt ggaatacaac aaatagcatt tcctccagct cccattgctg
    98341 aataccacaa aacaccatct tttttacata gccaccacag ataaccgtat tcattactat
    98401 tcattttaac tgattcttca atccacgatt tagatataat acgtttatta ttccaaatac
    98461 catcatttaa atacagaaaa ccaaatcgca acatatctct agcactcaat gtaagtcccc
    98521 agccacctat agaataaccc tgtctatctt ttgcccaacc cttaagattt tttccaaaga
    98581 aatcttcaaa accaaaatct ttcatatcat aatctggtat aactttcata ccaataggtt
    98641 taaataagta ttcattagca aattcacgag cagattttcc agtagttttt gttataatag
    98701 ctgaaagtag gtgcgttcca gctgaagaat atttgaaagt accaatttcg cctttttgac
    98761 caagttgatt caaggtatat tttatccaat ctttttgttt gcaaagtctt tctaaagact
    98821 cagtcatatt tttaaaaggg tatggtgcag tcattgtaag taggtgacgt atagttactg
    98881 cttttttaca tatttcagaa ggactataag tatattcagg gaaaaaatca acaacctttt
    98941 ggtcaacatc ttttatatat cctttatcta ttgcaatacc tattaaggct gatataatac
    99001 tttttgtaac tgatgcaaca tgaaaagtat catcagcatt atatccatta tagtactttt
    99061 caaagacaac ttttcctttt cttgcaataa ttattccatt tatattacta tattgtgaga
    99121 ttattaaagg ttcaagttgt gagagttttt ctgaactcat gccaacactt gaaggattta
    99181 ctttttcaaa tattaaatct aagcaattgt ttttattcat taaagatacc tccctgttat
    99241 agattttgga ttttctttta gagtttttgg agaaccttct gcaattatat aacctccttt
    99301 gtcaccacct tctggaccaa gctcaacaat ccagtcacaa acatttaata catctatatc
    99361 atgttcaaca acaattacag aatttccatt ttcaaccaat tcatctaata attgaatcaa
    99421 cttagaagta tcgtatagac ttagaccagt agttggctca tccaatacat aaaggatatt
    99481 accatttcgt tttttaccaa tttcttttgc aagtttgatt ctttgggatt caccaccact
    99541 taaagttggt gtaggttggc ctaattttat ataccccata cctatttgtt ctaatacatt
    99601 taagtgtgaa acaatatttg gaatatcctt gaagaaatgt acagattcag aaacactcat
    99661 atttaaaata tcatgtatat ttttattttt atatttaata gataaagatt catcattaaa
    99721 tctttttccc tgacattcac tgcatatatg gtctatactt agattatttc ccaaccagac
    99781 cttttcatat ccactaccac tacatttagg acaagcccct ttggagttaa atgagaaatg
    99841 accagctgta aatcctcgtt ctaacgattc tggctgacct gcaaatagtg tacgtatctt
    99901 atcccatata ccaatataag aagcaggagt tgagttcata tttttgccaa taggagattg
    99961 agatatctct gaatatccag aaatatgttt agtaccaatc agtctatctg caatagtttc
   100021 aacaactgca taatcgtctt cctcacctat ttcactctct gaagaattta tttgattatt
   100081 gatagtatgg ttattaaatt ggcttctaag aagaggaagt agggtgtctg atataagtga
   100141 actcttgcca ctacctgatt ttccagatat tccaaccata gcacccaaag gtaatgatac
   100201 agttacattt ttaagattat ttgtatttgc attttgaata gttatacaag gtattttatc
   100261 agtatgtgta atgtttttat tgcttgttct attaggcatt ggatattttc cagatagata
   100321 ctgtccagtg agtgatttgt cggattgaag tagaccttct aaatctcctt gatatactaa
   100381 ttgaccacct tcaacaccag cttttggacc aatatcaata atatgttctg ccattttaat
   100441 tgtgttttta tcatgctcaa ctactatgac cgtattgcct aaatctttaa gtttctttat
   100501 tgattttaag atgtctattt tttctgattc atgcaatcca gctgttggtt catcaagcac
   100561 ataaattaat gagtccatct ctgaatcgag atgtgaattt aaaaatagtc tttgcatttc
   100621 cccaccactc aaagttgaca tttctcggta taaggataga tgacctaatc gtgattctat
   100681 taaatgttga gttttggata aaatatcatt tacaagattt gtaccaaatg tgtttaaatt
   100741 accttgattt attaagagtt taaggaaatc atcaatttct aaaatcgtca tttttccaag
   100801 ttctccaata tgttttccgt ttaaaagtac tctacgtgct tcttcaccaa ttttaaaacc
   100861 attgcaatct gaacaggcag tcatagtata aactccattt aaatcttcgc cccttttgta
   100921 acgattgtga aatacctttg ataaagagga acttttttta ccattttcat aatgaccata
   100981 gagtacttca tttcttactt cttcaggtag ttgtaagaat tgtatgtcta aataatcatt
   101041 gaatttttta gaaaatactc tcaaatatcc aggtgtaatc tttgctctat ctaagacttg
   101101 ttttagggta tcatgcttat caaggactaa tttttcaata ttaatctcaa aatatgcacc
   101161 atgtccagag cacttcatac acattccatc tgaagagttg tatgagaaat aacttggtct
   101221 taatcgttct tcctcatatc cacaattatt gcaaattaga ttatagctta caggagtatc
   101281 acacatagta cacattattt gaccttccac tgaatacaat agtgtaagca tgttgagaat
   101341 attggttctt gtgcctactg ttgaacgagg attgctctgg cgaataatat tttgttgaac
   101401 agctatagtg ggagctaaac cttgaatatt atcaaactta tcttcactat caatacctgc
   101461 aagtatacct aaagattgca gatattgttt acgcccttcc tcaaatacaa tgtcaaacat
   101521 aaggctagac ttacctgagc cactgacacc tgttgcaaca acaagcttat ctttggggat
   101581 agaaacatct atatttttaa gattgtgtat ctttgctcca ttaattttta tttctttcat
   101641 tggttcacct cattttatca attttatcaa accgtaaaat agggatatat taatccttaa
   101701 tacaagaata gattaggtga ggttattaaa aaggttctat aggtaaatat atatcgacca
   101761 agtgtctatt ttgagggtga ttgtgtgggt tgttaagata tacttcaaaa gggaaggagg
   101821 cacgtagctt ataattacca tttgatagcc attcattata cataaaatcc cacgcatcac
   101881 tatattcaga ttttgaaata tcaaaatgtc ccacaagata ttttccagaa ggtattatca
   101941 tattgccaag attgtcattc tctttgacaa caatgttatc tggaatggtc atgcaaatac
   102001 tagtccttaa ttgatgctcc tgtgtaaatt gtggattatc atgataaatg gctaatattt
   102061 gtgtgttttc aagtccaagt agattctgct cacttgcata tgtgaataac cgttctaaaa
   102121 gttttgggaa agtactggtt agattaccat atgaaccagt atacctagtg taaatagtat
   102181 tcatattatc aagttctaga atttcaattt cacctttaac ctctctagta ttcttacatt
   102241 taggttttga tatgcttcta ttgtactgag aaattttata tggttctttg caattcttgc
   102301 tataattgtt tctatatttt atagggctta ttttatagta atttttaaat gctcttgaga
   102361 aaactgctga atcagtaaag ccaaagtagt gtgcaatatc agtaacagtc atgtcagttc
   102421 tatgaataag aaaagcagtt gcattttcta gttttagcct atttacatat tgtgccaaag
   102481 tttctttttc tattgctttg aagattctat gaaaatgaaa ttttgaaaaa cctgctatat
   102541 tagaaagttc atcaagagaa agaggttcat gtaaatgttc ttctatatag tcttgcactt
   102601 tgcaaatacg atttagatat tcttttttac ttttagcatt tgtcatatat agccctcctt
   102661 attgtgtaaa atgtgtatca attaatttat agcaatatag taataaaatt ttatgttttt
   102721 gtaatttatg ataaataaga tagcgtttaa ttttttataa ttgataaaag atatttataa
   102781 ttaataaaag atatttataa ttaataaaag atataagatg ccttatattt gtctttgcat
   102841 ataagtatag tcttcgtaat aattagtata ccatagtgat ttatttttaa ttgtgtattt
   102901 atataaatac acaacttatg atatggacga attattatgc aaataagctg taattaaata
   102961 aattgcaata taaaccagtt gaaacataag ttagggaaat attatcaaag ttattactta
   103021 gcataagagt atagatggaa taaaataaga ttaaaaaatt acatactaaa tttaataaaa
   103081 tttttatatt aaaaataata ttaagtttat tgtttaaata aaaaagttaa atctacacta
   103141 ttaacttatt atacttaaaa ctttaaaatg aaaatatcaa agaatacttt ttaataaaaa
   103201 taatcattta ataagttatt taaaaatcta aaaactttac aacaaattat ctatttaaat
   103261 tggaggagtg ggaatatgag taatagtttt tatcaattaa attcagcagt attatatttt
   103321 aatgaaaaaa gagatgtaaa tagaataagg tttaatcact atgtaatgag aaaagaaaat
   103381 atacaaagat taaaaggaac tctgccaaga ggacaattta tgatgacagt aaggaaagct
   103441 gcatctgacc ttgatgtatc tatatctaca ataagtagac ttgtaaatga atttatagat
   103501 ttaggtatat tgagattaat aagtagggga gtaaagggaa attgttgttc tgtatatagt
   103561 tatgtttgtt ctgaaagtag taatgcagaa attgtaacaa agaatggtga tattttcaaa
   103621 aatatagaga aatacattga tgcaactatt aacaataacc aaaaaacaat gaaatataaa
   103681 catagaaatg agttgtttaa gaacagtaat accaacatat acagccgtat aaatcaagag
   103741 agtatagaca aagattatga tttgataatt catactgggt atgaaacaga aaatgagaca
   103801 aagaaaaaag aattattaaa aaataattta aataaaaaga atttaaataa aaataccttt
   103861 gaaaattcgg atgaagattt gactgaagat tctacttaca aaaatccaga aagcatacat
   103921 gaaattatta taagaaaatt aaatagtgaa tcaggaaaaa attttaaagc tgatttgagt
   103981 ataactaagg cacttataga taaaagatta aaagaagggt atagtttaga agatttttac
   104041 aaggttatag aggcaaaggt aagaagatgg agatatacag atatggaaat atatatagaa
   104101 ccaacaattc tgtttgggta tgaatttgag tcgtatttaa atgaggagag ttctttatct
   104161 gcttgtaatt atggtgatat gtgttatgaa gatatgtatt gagatattag ttgcttttta
   104221 gttgtttaaa atatgtttat atataaatat aaatagtgta ttaaaatgga gttgtctcaa
   104281 aatagagaga agcctcttct taattgttta aatgatgaaa atatatttga tttaatacaa
   104341 aggagagtgc tttatgagtt agaagattta ttttgagaca ctcacttttt ttaatatact
   104401 ggagaaatat aacccatttt aatagctttt gtaatagcct caactgatga tgaaacatct
   104461 agcttgtcat atatgtgttg taaatgattt gataatgttc tttcacttat atacaattca
   104521 tcagcaatta tttttctttt tttaccacta cagataagct gtaaaattct tttctccata
   104581 gtagttaaat cttcaataat tacttcagta ttttcagatg gaaaacaagt taccccttga
   104641 tagactttta ataatgaatc aattaaacta tcagggctaa tattcttatt gaggaatcca
   104701 tagataccta tttttttagc ctcatgttta taaactggga ggtcgtatcc agtcaagatt
   104761 attattttaa tagttgaatt agtctctaat aaattataag ctacttttaa gccatcacat
   104821 tcacttaagc ctctaaggtt tatatccatt aagacaatgt ctattttttt atcttgaatc
   104881 atttctgaaa gattatggat gtcctgtgtg gaataaaact gttcgatttc tttgtattct
   104941 tctagtgcaa ttgacaagct tttagcaaaa agcatatggt catcaactaa caaaatattt
   105001 ataagaacca tctcctttca tagggattgt aatctgtaca caaactccat gaggtatatt
   105061 atcagaaaca cttatcgttc ctcctagatt ttctacttgt tctttaattg atataatccc
   105121 tttgtgtttt attgtatcaa aagtaatttt agttatatct aaaggcgttt taaaagatgt
   105181 atttgccaca ccattatcac taatatttaa ttttattata tttttttcta gtgctaaagc
   105241 tatccatgca tggctaccat ttgaatgttt atacacattt gtcaataatt ctttaatcag
   105301 tcgatatatc aatatatcat atggttcaac taagaataaa gtatcagaac acttaaatga
   105361 aacacaaata tttttttgtg gaaaggatga agaaacactt tcaattaaat tctgataatt
   105421 ttcttttact gttaaatttt ttaaaataac aggatgatag tcttgcattt gcttccttat
   105481 acatgtattt agattgttaa gtgtttcata tataatatct tgaacatctg ggcgatatga
   105541 cttactcatc atgtttttta ttgaaagcag gttctgtaat atgtcatcat gtaaaaaatt
   105601 agaaaactct gtttttagtt gttcttcttg ttgtaatttt tctaatgcaa aagtatactt
   105661 gctattttta actactttat ttttttcatc tctaaggtta aactccaaaa taatgttaca
   105721 gaggaaaatg agcataaata aaacatttat agctattaat attatagaaa aattcccatt
   105781 ggcaaatagt acgaccaagc taattactaa aatacttata aaaagaaata tagccctttg
   105841 ttttatgtta aaaactgttg aaataggaaa actatcattt tctttaagtg caataccatg
   105901 aatactcata aaaaatacca gtacagttag atagattcca aaattaccaa tatgatttga
   105961 tattcttagt gtaaaaaaat aataagtaag gaatcctata attgttataa atactgaaat
   106021 cgatataggt tttttttcgc tttttatgac aaaaacaacc cttttcaaat gataaaaaat
   106081 aatatagaaa aagcttatta tactaacaac aaactgtatt ccgtacatac aagcatacgt
   106141 tctgttagaa ataaatgctc ctacaattgc accaatgcag gtgataagca ataaaatgtc
   106201 tgttatctta cggaaattgt atccactacc ttgaaacaaa aataaaaata taaatttaat
   106261 agagacatac actataactg tgcttaatat tttaaaaata atagtgccta ttggtgtggt
   106321 tacaaatgat aagagtaaat accaactgtc tagtgctagt aatccacaaa acaatgaaat
   106381 aatgttattt tctcggacat tacaagaggt tatatatgtg atgtctatga gtaataatgt
   106441 tgaaattatt aagggaataa tgctttgaat attcatataa gtttcagtgc ttgtagatat
   106501 tcccatgaag agaagtgata gaatgtagtt tcctaaaaat agtattttta aattaaaatt
   106561 tgtcaatctt atacacctcc ttatgagtta attatattaa ttttatgact aaatcaaact
   106621 taagaattta tagttttaaa ttatatcaaa tacttataaa tgaagtatac caaatcgtca
   106681 cacctttaag cttgacgatt tggcaaatat tattttttta atacaatttt acaacaggat
   106741 ttaatagtaa gtatgtaata tatcaaatat actacagaag ttaagaaaat tgcaataatc
   106801 acaggtatgt attgtgaaag tgaatttcca agtaaattct gcatcaaagc agtcttataa
   106861 accaaggtag caaatataca gtccactata ccaagtaaaa acggaatatt aaaaaatggc
   106921 aatacttgtt ttttaataat ttttttaatt tgtatattag tataacccat tttctgtaaa
   106981 attttataat cagatgttga atctgaaatt gctgatatat tgttaaagta taaaatactt
   107041 ccaacagcaa taaagaataa taccacaaga aatccgatta acagaaatgt agaactatta
   107101 attgataata aatcatttat cctgtgagaa tatccttgta aataagggct tccatctaaa
   107161 taatctgaaa tattactata taaattttca ttatttttaa ttgatttacc attaatactt
   107221 aaaattcttg tcattggtaa tttattttgt gctatttgct catatatact atcattaacg
   107281 ataagtgttc caacgctatt ggcaaaagaa atagcattgt ttaatgatgt ttcccttaca
   107341 gctacaggtg tttctttacc attaacaagt aatggataaa tcgttccatt ttcactatat
   107401 ccatcattat ttggttgata tttcattaaa atacattcat tatcccttaa aggggtaagt
   107461 tgttttagta gctttgttcg attttgtgcc tttaataaag tataataatc agaaaaagat
   107521 atacattcaa atcctgattc tcttgaaata acttctttag aagaactact attggataaa
   107581 ttattcttag atgtaccaat ttcatattca aatggaaggt cttttgatga agattttacc
   107641 ttataaatat ttgtctgtgt aaaaataata tcatctgtat tagacgtata ttgactgaca
   107701 atttgtttta catcttctat ttgtttattt ttttctactc taaattctat ctctgaaggt
   107761 gcaatacgcg aaacagatgc aatagggtag tataaggaca gtgccataac acttgaaact
   107821 gtcaaagtag tagcagagag taatgtaagc ataattagag ttttagagtt tgaacgtata
   107881 cgatagataa agtttggaat agctattatc ttcatatctg tgtagaaagt acgtttattt
   107941 tttttactat tttgcataat atatggaaga aaggaattga taaagagaac tgtaccaatt
   108001 acaatgataa tcatagttat caagcccatt tgataaaatc caatacttac ccatactgat
   108061 ttagctccac gaagaatatc tagtgataaa caatacccgc ttaaaatcat aataaacccc
   108121 ataaaggctg gaatttttct gaactttaat tttttttctg cacttttttc atatcttatc
   108181 aattttacaa gtggagtctt ataaaaaaat ttaccatttg atacagctaa gactaaaaca
   108241 actaatgcta taaagataat tgttttattt attgcattta tattaaaaaa tggtatctgt
   108301 gaattatcaa ttgataaatt aagtagtgct gtaattccaa agacaatacc cttatgtgcc
   108361 aatgctccta ataccaatcc aataataaaa gctccactac aaattaatac attttcaaag
   108421 gtaagtagcg ataatattgt aaacttacga tagccaagta aagcatatat acctaattct
   108481 tttgtacgac gtctcaagaa gaatcgattt gagtatgcca tatagaagat gacaaatgcc
   108541 atcaaaaata tcgaaataac attacacata gattcaactc taccatcagt tgaaattttt
   108601 tctagcatta tcttattaac agaaaatgaa gtaaatgcga aaaatacagt aataacaaaa
   108661 gagactgaaa gtagatatag agaatagaat gaaaagtttt ttttaagatt ctttattgcc
   108721 gtataaaaaa tgttcattaa attatcctcc tatcttttag tatccaattt tgcaatttct
   108781 tgaataatca actcataaaa tgtatgtcta ttattctgtt gtttatttaa ttctttaatg
   108841 atatgaccat ctttaaaaat caaaattcta tttgcaaaac ttgctacata ggcatcatgt
   108901 gttaccatta aaattgttgt tttcaactcc tcatttgctt cctgtagtga gtggagtagt
   108961 tcagtagctg aattagaatc caaagctcct gttggttcat ctgcaaagag aatactagga
   109021 tgttttacta ttgctctaac tgctgaagct ctctgtcttt gcccaccaga taattcattt
   109081 gggtatttat ttaattgaga agctatgcca aatcgttcag ctagactctt taccatgttt
   109141 tctattttat ctggattgag tttctgaagt gtaagaggta ctgaaatatt ctcgaaaatt
   109201 gtaagactat ctagtaaaaa atactcttga aagataaagc ctaaattatc cttacgaaaa
   109261 tcagcagcac aagtgtcatt aagcgatttc aaatttatat tatttatgaa aatatctcca
   109321 cttgttggtt tatcaattgt agataataca ttaagtagag ttgttttccc agagccagaa
   109381 gctcccatta tacctataaa ttcaccttct gatacattaa aggatacctt atctaaactc
   109441 ggctgttgcc ctttattata agttttagtt atgttattta cttttaatat tgtattcatt
   109501 gtatatgtct cctttcgtct taatatagtc aaattatata ttaaccttat tgtttcttca
   109561 tgagtaaatc acgcaataat tctacacaaa ttacttatat cacaatatat tgtttaaaat
   109621 ctaactttat taggtttggg atgatggaca agattttaat ttaaaagagt gcataggtat
   109681 atataatggc ataatgtgga tttaaattaa aaaaaataaa ataaagccat aaatattgaa
   109741 attttcaata tttatggctt tattgcttgt aataattaat agaatatata ttttttatta
   109801 atcatctatt tcaaattcta atattttacc agtaattgca ttaattgtta tctcatattc
   109861 agtttttcct tttattattt caccttcata ttctttgtca tcttcatcat acttaaattt
   109921 tactattttc ccaccaggca ctttatctag cattattgat ttagcttttt cagcactaat
   109981 aatagaactg ttgtcattag tattagagtt attcttatca ttatcatcaa agtcatcatc
   110041 agaatcattg tccatgtcaa tatctacaat tcttccatca aatgcactta tctctaattc
   110101 atatgttttc ttatttttta ttactttagc ctcatattcg ttatcttcag catcatattt
   110161 acaatagatt aaattaccat taggaacagc atctaatgct atagacttag ctttatccaa
   110221 tgatatattt tgtgtaccta aattattatc atttaagtca tcatcttttt caatttctat
   110281 tattttacca gagtaggcat caatttctat ctcatatagg atattatcct ttataacttt
   110341 gcagtcatat tcattatcat cttcatcata ataacaaact aaaatattgc ttcctggaag
   110401 agcttgtttt aatatttctt tagcctgtat taaagatatt tttttagttt tatttcttat
   110461 gttcacattt tttagtttta aaatatcttc aaatgctttt tgattatatc ctcctcctac
   110521 ttgtgttatt tcatctatat ctttattttt aataaattct ttttgactat ttacaaggct
   110581 accattagat atcattatag gagaattttc tttagcagct agtactccta ttgataatga
   110641 atctactaat gcattttctt ggttaatacc atctttagct acaaatacat tatttatttt
   110701 tttatcttta taaaatttat caataatttt tgcattagta ttgtttctat ctgaaccact
   110761 gattctttct ctgtttggat atttctttac tgtattgtct gataaaatct tatttcctcc
   110821 aactatgtaa gattttttta tagacctatt gtttaagaaa tttatactac tatcattgct
   110881 gttttcatct gatactaata ttataggcat attatgtatt gctgctggag aagctatact
   110941 aactgcatca gatagtccct ttagtccatt tacaactgca acattttcta ccttttttat
   111001 cttatctatt tctttaagta catttgtaga catttcatat atattgtttc ctactatttt
   111061 atttattttt atgttaagtg attttatttc attttctact ttagaagaaa tgctatttcc
   111121 actatctaca atgtacacat tatctacacc aagcctttta agctcagcct tagttgaatt
   111181 ttcaatactg ttgttgttta ctaaaagtat aggtgcattc tttagcttag caaatggatt
   111241 tgcacaaagc gcactttgaa tagaattacc attaactata atggctgttt ttgattgaac
   111301 ccatcccaat ttacttactt ctactgctgt ttcatatctt gttttaccta ttaatctttc
   111361 ttgctttgta gtattgtctg caaaaattgc tgaagaacta gaaaaaaaca taatacctga
   111421 tattaatata gctaaatttt tcttattcat atttttacct cacaatcttt aaaaatttgt
   111481 tatttagcat acttaataaa atataatctt aaaatcaaat tgatgctgag tttgaagtta
   111541 caaaatcaac aaataagatt tttttaatac aaaattttcc tttttatatt taacattgta
   111601 tcacaaatat aaaaaggaaa aaacttttta aaaagggtat acactattca ttttttatct
   111661 tataaataag tctttaccac tgttttatat attttaaaat agacacaaga cctatttcta
   111721 aatcttttag gtgaaatttc tttttaaaca tatctaaaaa gtatttgtag taatattaat
   111781 ggactgaatt tcttaaagta tatatttctt tacatgttgg agtttgtgaa gtttgagaat
   111841 tggagggtga aagaaacatg taatggatta atattaaaga actgtatttt tataatattt
   111901 gtcttaaaaa taaaaaaatc tattgacttg aagttaactc caagtagtaa agtataatta
   111961 tacaagaatt atatacttgt aagaatagtt aaagtagaga gaaaaaacaa acaagtttta
   112021 aagggggaag taaaacaatg gaggcaaaaa aattaggatt tggattaatg cgtttaccaa
   112081 taaaagatga aaatgatgtt acaactattg atatggaaca tttaaataaa atggtagaca
   112141 cttttttaga aaggggattt acatattttg atacagccta tgtgtatcac atgggaaaaa
   112201 gtgagatagc acttagagaa tctctagtaa aaagacacaa aagagagagt tttactatag
   112261 ctacaaaact tccattaatg gctttaaaga aaaaagaaga gcaagaaacc atttttaatg
   112321 agcaattaga aaaatgtggt gtagactatt ttgactacta tcttttacac aatataggcg
   112381 tgtcacatta tgaagtagct aaaaaatttg atagctttaa gtttattgaa gaaaagaaaa
   112441 aagaaggaaa aataaagaat attggttttt cttttcatga tagtgcagaa ttattggata
   112501 aagtcttgag tgagcatcca gaagtagact tcgtgcaatt acagattaat tatttagatt
   112561 gggataatga aagcatacaa tctagaaaat gctacgaggt ggcagagaag cataataagc
   112621 ctgtaattgt tatggagcca gtaaaaggag gtacacttgc aaagatacca gaaaaagcag
   112681 agaaattatt gaatgactac aatccagata tgtcaatttc atcttgggca atacgttttg
   112741 cagcaagtaa agataatgtt atgatggtct taagtgggat gtcaaatatg gaacaattat
   112801 tagacaatac aggatatatg caaaatttca aaccattcgt acaagaggaa tataatatta
   112861 tagatgaagc agtagagatt atcaacgaat caattttagt tccttgtact gcctgtcagt
   112921 attgtgtaga aggctgtcca aaaaatatcg ctattccaaa ctattttgcg ttgtacaatg
   112981 cagaaaaaca agctcttaat actggatttt caacacagat ggtctactat aataattata
   113041 ctaaaactta tggaaaggcc tcagattgta ttgaatgtaa acaatgtgaa gaaagctgtc
   113101 ctcaacacat taaaattata gatgctttaa agaatgtagc agaaaccttt gagaaataat
   113161 tcaatctata caatatcaag aggagaagat atgtatgacg atttcagaag ttagtaaaaa
   113221 atacgagctt tcagcggata ctttacgata ttatgaacga attggtttaa taccacctgt
   113281 aaatagaaat aaaagtggaa ttaggtcttt tacagaagaa gattgtgagt gggttaattt
   113341 cataaagtgt atgagaggtg caggtctttc tattgagaca ttaattgagt atgtagctat
   113401 gtttcaacaa gggagcagta ctatcaaagc tagaaaagaa cttttaatag agcagagaaa
   113461 ccaactagca aaaagaatag aagaaatgca aaaaactttg gaacgattaa attttaagat
   113521 tgatagatat gaagaaggta ttattgagaa agaaaaagta ttaaagagca gtagaaataa
   113581 gaaaatggag gcagtatctt atgagtaaaa atgtattaat agtatcagct agtcctagaa
   113641 aaggtggaaa ttctgattta ttgtgtgacc agtttataca aggggtatta gaatctaaaa
   113701 atcaagtgga gaagatattt ttaaaagata aagatattaa ctattgtact ggatgtggtg
   113761 cttgttatga aaaagaagca aattgttcac agacagatga catgggagaa attcttgaaa
   113821 aaatgattga ggcagatgtg attgttttag cgactccagt ttatttttat actatgaatg
   113881 cgcaaatgaa aactatgatt gatagaactt gctctagata tactgaaatt tgtgataaag
   113941 atttctattt tatcgttaca gcagcagatg aaaatgtggc tgatatggaa agaacaatag
   114001 aaggatttag aggatttaca tcatgtctaa atggttctaa ggaaaaaggt atagtatatg
   114061 gtgtaggtgc ttggaatgta ggtgatatta agggaagtaa ggcaatgaaa caggcatatg
   114121 aaatgggtaa gttggcgtag tatgtttgta taaaattgta taaaattgaa tatattctta
   114181 tcatttcaac aataaaaaga ggcttatctg tattttgaga cagcctcttt gtgctatatc
   114241 atttattttt attctatatc cttattatac cctttatttt tttatgccta tttaagtatc
   114301 tgttgttact catatatttt aataattacc cttaaaaaac tatacagatt cctgcataat
   114361 attattttct ttagtaatta atttttctag gtttttccaa tccatttctt ccatatttgc
   114421 aaaataatga ccacttccta tgcaagtcag gtaagacttt ccatctaatt caaacgaaga
   114481 acctccaata cactttgaat tacatttctt acaagtacga gttttagtta tactatcttt
   114541 aatagtttta gagcattcct ccacagcatc tttatatgta tttagatgaa aaagatttgc
   114601 tttaactctc catttttttt cattacattc aatagtaaat aagctacgtt ttggtttctt
   114661 agttgaatat actattttgt aagaacgagc acctgttttt ggttcaattt tacaatctaa
   114721 tgatttacca agttcatgta aatgacatgc aatatcataa tctttaccac ttagtacttc
   114781 taacatttct tctgttgttt ctgctgttaa ttcacttttg ctcatattaa aaaaatcccc
   114841 ctatataaat aataatttca tatgaaaata attaatataa gtatattaaa taaaactatt
   114901 aaaatcaata aaattactgc aatcttacat tattgggcat agaatgagag ctaatgattt
   114961 attagaaata agacttaata gtatgaaaat ttacttagac gtggtacaat tctataaaag
   115021 atttaaaact aggaaaggag aaagttgttg agatacggcc aatataacaa tttatttata
   115081 agttgtaaat ttattatgag attaattaga ttgttaagta atactatcaa aaggtagttt
   115141 tttggatttt cagcaacagt ggtagatatt gataattttt tggttattat tatatttagc
   115201 tgttatattt tcaataggct ctatgataac tagggtaaat aaggtatggg taaaggtttt
   115261 attatttata atagtgggat tgtcaactat agttctttca tatgtaataa cttgattatg
   115321 caaaattcta tgaagcagga accctgtgac tttagtcatg ggaggttcag aatttaaggt
   115381 taaaaaataa ctttaatctg taaattctca aaacaagaat tctcatgttg gtaaatttct
   115441 agatatgaga aaaaaattga catcataaaa aagtaatttt agagcgtttt tttacgaaaa
   115501 aattcagaag taactatttt gaatgacttc acaaaatttt atatataaat aaagtttggc
   115561 acgttaattg ctttaataaa agttaacaag acacaaataa acataatcat ctaagtattg
   115621 attatttgaa gttttagatt tgaagtttaa tctaaaggtt cgtattaata ttggtgttta
   115681 ggaaatttta ttttcctgta aatataactt aataatagga ggtgaagtca tgtcaaaagt
   115741 agtaatagct acagagaaag ctccaggagc aattggacca tattctcaag caattcaagt
   115801 tggaaacata gtttctacat caggtcaact tccaatagat atgaagactg gcgagttagt
   115861 atctgaccca aaagaagcaa caaaagcttc tttagataat gtaaaagcaa tattagaaca
   115921 agctggtaca agtatggata aaatatttaa gactacagta ttcgtaaaag atttaaagga
   115981 ttttaatgat attaatgaag tatatgctac atattttaaa gaaaatccac cagcaaggtc
   116041 atgtgtacaa gttgctcaat taccaaaaga tgcagtttta gaaattgaag caatggcagt
   116101 attataagta ttataacaat aaaaccaata acaaaactaa taaaaattaa aaactaataa
   116161 aaaaagtcta caattaaaaa agtttatatt aaaaaagtct atataaaaat ctatctaaat
   116221 atttaactat tgagcttttc tcatataatg tatattttta tgtcaaaaat atatttgtta
   116281 tatgaggaaa gctttttttt attattgtat tgtgatttat tttattgtct gcatattata
   116341 attaaggtta ctatataaaa caaacttttt ataaattaat attgtctgtt ttaacgcaaa
   116401 tatataaata agtaatgttt tatatatatt ttaaagagtg actatatgtt aaaatatagc
   116461 taaactgata atttggtaaa ttaaattcta atgggggaaa ctatgttaag taaattaaaa
   116521 gaatttcaac aagaaatgat aaaatacact gaaacagtag ctagtgtgtt agatgtagat
   116581 attgaaatag ttgacgatag attaataaga attagtggta caggtctgta taaatcaaag
   116641 ataaatgaaa gcgttgttac tgagggcttt atttatgaca atgttataca gacaggtcag
   116701 gaattagtcg tattggatat atgtgataat cagctttgta tagaatgttc ccattacatg
   116761 aaatgcctaa ataaagtaat aatagcagtt ccaataaagt ataataatcg aactatagga
   116821 gtaattggtg ctattagtac agataaaact aaaaaagtag aaataagtgc aaaaatagat
   116881 aattatttaa aatttgtcaa tcatatatgc gatttaattt ctatgaaaat agaagaacat
   116941 gaagcgtcaa aaaatagcag tagaaaaatg gatatgatga tagaaatcat tgaaaatgtt
   117001 gaaaaaggcg ttataatact agacataaat agcaaaatat cttatataaa caatatagct
   117061 ctaaaaaaat tagatataga taaaaatata atagaaaata tagtaaatat agtatctgtt
   117121 gaatcttcct caaatggaca tgaattacta gaaattgata ttgataacaa aatttataat
   117181 ataaatgcca aaataattcc ggtatatcca tatataaatc aatacgacaa aataataata
   117241 tttgacaaga catatatcaa tcataaagga catggaaaag tgaatagtgg ctggggaaat
   117301 agtgatatag agtctataat tggaaattca gaagcaatgt taaaagtaaa agagagaact
   117361 aagaaattag caaagtcaaa ttcaactgta cttataactg gggaaagtgg tacgggtaaa
   117421 gagctaattg ctagggctat acatgctgaa ggtagcagat ggaacaagcc atttattgcg
   117481 ataaactgtg ctgctattcc agaaaatctc cttgaaagtg agctatttgg ctatataaaa
   117541 ggtgcattta gtggagctag tagtggaggt aaagtaggta aatttgaact tgcaaatgaa
   117601 ggtgttatat ttcttgatga aataggagat ttgtcaatgc ctttacaagc aaagttactt
   117661 agagttttac aagagagaaa atttgcgaga attgggtcaa ataaacttat agatttagat
   117721 ataagagtga ttgctgctac aaataaaaac ttattgaaat tagtaaatga aggtaagttt
   117781 agggatgatt tatactatag attgaatgta attcctataa atttgccacc tcttagggaa
   117841 agaaaggatg atattgaggc aataatgatg aagtttgctt ctaaatattc tttagaatta
   117901 ggtattcagt taaataaaat agaagaaaat gtaatgaata tgttgattaa ctataattgg
   117961 ccgggaaata taagggaact ggaaaatgca gttgaatata tgatgaattt ggttggagat
   118021 gatggaataa tatataaaga tatgcttcca ttagatattt taaactatta taatattaat
   118081 ggaaatattt ataaaaataa ggatgtaaat ataatatttg aagatgatat agttggaggg
   118141 atagtagaga atcaagaaag gatactttca attaaagaat tagagttgac ttacataaac
   118201 aagttgttga ataagtatgg aagagataca aagacgaaga agaagatagc aaaagactta
   118261 ggcataggtt tggctacact atatagaaaa ttggaagagg aacagtagta atataatatt
   118321 aaaatgatag gtatttgtgt gtttttatag ataggtattt ttactttatg gtggaggtgt
   118381 tattatgcaa tatgcgatag agctgtatta tgataaaaaa acggaaaagc aactttttga
   118441 tttatctaaa aaaatcgctg atgaaaaaat tagtacgaag tatttagaat ggaaaacaag
   118501 acctcatctt actttggctt gtttcaatga tgtggatgag gcttgttgta tagacaagct
   118561 aaaggggttt gcacaaaacc ataaggtaat acctgcttac attggttcag taggcatgtt
   118621 taatgatact aaaacggtgt ttgtatcacc tataatgaat agcagtatgt agcagtttca
   118681 gagagaatta tatgaggtac tacaagattt tgattcaaat ggttgggaat ggtaccaccc
   118741 caatcgttgg gtaccccatt gcacaatagc acttactgga gatgatgaaa gtgaggcttt
   118801 ttttcgggca agtgatgtat tactgcgtga gttcaaaaaa ataagtggtg agtttgtctc
   118861 aataggattg gttaaaatta catttcctgt ggaagaaatt tttacagtga atatgaatag
   118921 gtaactttaa ctctgttgtg gatgttatga atattttgta tagtgcattt catcagataa
   118981 atgcgaagtt gcgaatttcg acagctcaat agtcgcaagt agggcacaat ggtacacata
   119041 ttgcactttt gcttattggg gggacgccca tgtaaacttc tgtaagaagc tatgaaaaga
   119101 tttaagccat tttggaggct ttgggtaata aagaatattt gggtaataaa gaatataaag
   119161 tatataaatt tatagagttt atgcgtaaga aggttatagc catatattta tagaaaataa
   119221 aagtagtaat atatctgaca aaacaataga catataaaaa ataagagcat aataaaggaa
   119281 gaattaagat aaataaacga tttctcgaat tgataattct cgtattgata aaaatttccc
   119341 aatatgagaa ttttttcttt tataaatctt atttttcaca ctcaaaattt ataaacttta
   119401 aagaaatttt ataaaagtat gtaattccaa cataaaaaaa ttgtttttag aataaataat
   119461 attggcacgg taattgcttt gctataaggc acaaagataa aaaattaaaa tgacaccgaa
   119521 aaatttgaaa ggggaatata aaataaatga gagaaataaa atggaaatta aataacttac
   119581 ctaaatcaga ggaaaaagaa aaaggaattg aatttttaaa agatgaagag attgcaaagg
   119641 ctaaagcttt tcatgaaagc tttccacaat atgaaaaaac tcctttagtt aaattagata
   119701 acttagcaaa atcactaggc gtaagcggaa tatatgttaa agacgaatct tatagatttg
   119761 gtttaaacgc atttaaagtt ttaggtggtt cttactctat gggtagatac ttagctcaaa
   119821 gattagatac agatatatct gagttagggt atgataaatt aacttcaaaa gaaataaaag
   119881 aaaaattagg agaaataact ttctttacag ctacagatgg aaatcatggt agaggagttg
   119941 cttggacagc taataaatta ggtcaaaaat ctgttgtatt aatgccaaaa ggttcttctg
   120001 aatttagatt aaataaaatc aaaggagaag gtgcagatgc tagtataaca gacttaaact
   120061 atgatgatgc agtaagatta gctaatgatt atgcagaagc tgatgaccat ggagtaatgg
   120121 ttcaagatac agcatgggac ggatatgaag aaataccagc atggataatg caaggatatg
   120181 gaactatggc taaagaagct atagaacaat taaaagaata tggagtagat agaccaacac
   120241 acgtatttgt tcaagcagga gttggttcac ttgctggtgc agttcaagga tatgttgctt
   120301 caatatatga tgaatgccca ataacagtag tagtagaggc tgatgaggct gactgttact
   120361 ataaatcagc agaagctgga gatggaaaac caagatttgt tggaggagat atgccaacta
   120421 taatggcagg gcttgcttgt ggagaaccaa acactatagg ttttgaagtg ttaaaaaatt
   120481 attcatcagc attcgtttca gcaccagact gggtatctgc taaaggtatg agaatattag
   120541 gaaaccctct aagaggagat gagaaagtaa tctctggaga atctggagca gttacaactg
   120601 gagcattagt ttcaatcctt gaaagtgaag atttaaaaga cttaagagaa gctttgaaac
   120661 tagatgagaa ctctaaagta ttattaataa gtacagaagg agatactgac cctgataaat
   120721 atagagatat agtttggaat ggtgaatgcc aaagtaaata aaagacttaa ggaaaagaaa
   120781 atcttaacaa ataaatgaaa aatttaagga aaataaaaac ttaaataagt gaaaacttta
   120841 aataaaataa aaactaaaac aaatgaaaaa tctaaataaa tgaaaaagta aagcaaataa
   120901 aaaagtaaag caaatgaaaa attcaaaata aaaaccaaat aaaattaaaa taaagtctaa
   120961 ataaaaattt aataaataaa atataaagaa ataaaaaatc aatagattaa gtgaaatgct
   121021 aataaattaa aaaaatgaaa tatcaaaata aaacgtcaac aaattaaaaa ttatatgggg
   121081 gaatatcaaa atgttaaatg aaacaagaaa aaaacaatta actgaagtat gccaagactt
   121141 aataagaaat gctagttatt caggtcaaga agaaaacgta gtaaaagcta tagaagaaaa
   121201 ttttgcttta ctaggttttg atagttggtc aagagataga tatggaaata tagtaggatg
   121261 tataaaagga aataaaccag gtaaaaaaat attatttgac gggcatatag atacagttcc
   121321 agttccagat gcaagtaaat ggagtgttcc tccttttgaa gcgagaatag tagatgggaa
   121381 aatatatggt agaggaactt ctgatatgaa ggggcaagta agtgctatga tggctgctgt
   121441 ttcatacttt gcagaagata ctaacaaaga ctttgaaggt gaattgtatg tagcaggtgt
   121501 tgttcatgaa gaaatatttg aaggtgtttc agctagagag ataagtaagg ctgttcaacc
   121561 tgattatgtt gtaataggtg aatcttcaga attaaaccta aagataggtc aaagaggtag
   121621 aggagaaata gtagtagaaa cttttggtaa accagctcac tctgctaatc cagaaaaagg
   121681 t
//
LOCUS       DAMJWC010000003       105822 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMJWC010000003 DAMJWC010000000
VERSION     DAMJWC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.003"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            30..1310
                     /locus_tag="PC503_000245"
     CDS             30..1310
                     /locus_tag="PC503_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF2526269.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNLAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDV
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1573..2964)
                     /locus_tag="PC503_000246"
     CDS             complement(1573..2964)
                     /locus_tag="PC503_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2526270.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2975..4195)
                     /locus_tag="PC503_000247"
     CDS             complement(2975..4195)
                     /locus_tag="PC503_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF2526271.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4209..4997)
                     /locus_tag="PC503_000248"
     CDS             complement(4209..4997)
                     /locus_tag="PC503_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2526272.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5014..6288)
                     /gene="larA"
                     /locus_tag="PC503_000249"
     CDS             complement(5014..6288)
                     /gene="larA"
                     /locus_tag="PC503_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF2526273.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6406..7119)
                     /locus_tag="PC503_000250"
     CDS             complement(6406..7119)
                     /locus_tag="PC503_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2526274.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7244..8503
                     /locus_tag="PC503_000251"
     CDS             7244..8503
                     /locus_tag="PC503_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF2526275.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8783..9349
                     /locus_tag="PC503_000252"
     CDS             8783..9349
                     /locus_tag="PC503_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2526276.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9550..10755)
                     /locus_tag="PC503_000253"
     CDS             complement(9550..10755)
                     /locus_tag="PC503_000253"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2526277.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10858..10964)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11056..11424)
                     /locus_tag="PC503_000254"
     CDS             complement(11056..11424)
                     /locus_tag="PC503_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF2526278.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11476..12753)
                     /gene="obgE"
                     /locus_tag="PC503_000255"
     CDS             complement(11476..12753)
                     /gene="obgE"
                     /locus_tag="PC503_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF2526279.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12864..13154)
                     /gene="rpmA"
                     /locus_tag="PC503_000256"
     CDS             complement(12864..13154)
                     /gene="rpmA"
                     /locus_tag="PC503_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF2526280.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13168..13485)
                     /locus_tag="PC503_000257"
     CDS             complement(13168..13485)
                     /locus_tag="PC503_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF2526281.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13500..13811)
                     /gene="rplU"
                     /locus_tag="PC503_000258"
     CDS             complement(13500..13811)
                     /gene="rplU"
                     /locus_tag="PC503_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF2526282.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13912..15333)
                     /locus_tag="PC503_000259"
     CDS             complement(13912..15333)
                     /locus_tag="PC503_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF2526283.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15351..16052)
                     /locus_tag="PC503_000260"
     CDS             complement(15351..16052)
                     /locus_tag="PC503_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF2526284.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGAESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16054..17898)
                     /locus_tag="PC503_000261"
     CDS             complement(16054..17898)
                     /locus_tag="PC503_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF2526285.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18217..19410
                     /locus_tag="PC503_000262"
     CDS             18217..19410
                     /locus_tag="PC503_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2526286.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19622..20442)
                     /locus_tag="PC503_000263"
                     /pseudo
     CDS             complement(19622..20442)
                     /locus_tag="PC503_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(20572..21363)
                     /locus_tag="PC503_000264"
     CDS             complement(20572..21363)
                     /locus_tag="PC503_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526287.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFVFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(21367..21696)
                     /locus_tag="PC503_000265"
     CDS             complement(21367..21696)
                     /locus_tag="PC503_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526288.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22181..22594)
                     /locus_tag="PC503_000266"
     CDS             complement(22181..22594)
                     /locus_tag="PC503_000266"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF2526289.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(22635..23765)
                     /gene="rodA"
                     /locus_tag="PC503_000267"
     CDS             complement(22635..23765)
                     /gene="rodA"
                     /locus_tag="PC503_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF2526290.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(23850..24134)
                     /gene="minE"
                     /locus_tag="PC503_000268"
     CDS             complement(23850..24134)
                     /gene="minE"
                     /locus_tag="PC503_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF2526291.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24152..24949)
                     /gene="minD"
                     /locus_tag="PC503_000269"
     CDS             complement(24152..24949)
                     /gene="minD"
                     /locus_tag="PC503_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF2526292.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(24973..25656)
                     /locus_tag="PC503_000270"
     CDS             complement(24973..25656)
                     /locus_tag="PC503_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF2526293.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(25754..28732)
                     /locus_tag="PC503_000271"
     CDS             complement(25754..28732)
                     /locus_tag="PC503_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF2526294.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(28744..29232)
                     /gene="mreD"
                     /locus_tag="PC503_000272"
     CDS             complement(28744..29232)
                     /gene="mreD"
                     /locus_tag="PC503_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF2526295.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29247..30140)
                     /gene="mreC"
                     /locus_tag="PC503_000273"
     CDS             complement(29247..30140)
                     /gene="mreC"
                     /locus_tag="PC503_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF2526296.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30150..31160)
                     /locus_tag="PC503_000274"
     CDS             complement(30150..31160)
                     /locus_tag="PC503_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2526297.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31281..31940)
                     /gene="radC"
                     /locus_tag="PC503_000275"
     CDS             complement(31281..31940)
                     /gene="radC"
                     /locus_tag="PC503_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF2526298.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(31985..32569)
                     /gene="maf"
                     /locus_tag="PC503_000276"
     CDS             complement(31985..32569)
                     /gene="maf"
                     /locus_tag="PC503_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF2526299.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(32789..33760)
                     /locus_tag="PC503_000277"
     CDS             complement(32789..33760)
                     /locus_tag="PC503_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF2526300.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(33776..34351)
                     /gene="rsxA"
                     /locus_tag="PC503_000278"
     CDS             complement(33776..34351)
                     /gene="rsxA"
                     /locus_tag="PC503_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF2526301.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(34366..34959)
                     /locus_tag="PC503_000279"
     CDS             complement(34366..34959)
                     /locus_tag="PC503_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF2526302.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(34972..35541)
                     /locus_tag="PC503_000280"
     CDS             complement(34972..35541)
                     /locus_tag="PC503_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF2526303.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(35541..36518)
                     /locus_tag="PC503_000281"
     CDS             complement(35541..36518)
                     /locus_tag="PC503_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF2526304.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(36541..37878)
                     /gene="rsxC"
                     /locus_tag="PC503_000282"
     CDS             complement(36541..37878)
                     /gene="rsxC"
                     /locus_tag="PC503_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF2526305.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38094..39038)
                     /locus_tag="PC503_000283"
     CDS             complement(38094..39038)
                     /locus_tag="PC503_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526306.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39149..40423)
                     /locus_tag="PC503_000284"
     CDS             complement(39149..40423)
                     /locus_tag="PC503_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2526307.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(40555..40926)
                     /locus_tag="PC503_000285"
     CDS             complement(40555..40926)
                     /locus_tag="PC503_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2526308.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41154..41753)
                     /locus_tag="PC503_000286"
     CDS             complement(41154..41753)
                     /locus_tag="PC503_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526309.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(41954..42166)
                     /locus_tag="PC503_000287"
     CDS             complement(41954..42166)
                     /locus_tag="PC503_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF2526310.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(42239..43954)
                     /locus_tag="PC503_000288"
     CDS             complement(42239..43954)
                     /locus_tag="PC503_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2526311.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKVKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(43954..44508)
                     /locus_tag="PC503_000289"
     CDS             complement(43954..44508)
                     /locus_tag="PC503_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2526312.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(44501..45103)
                     /locus_tag="PC503_000290"
     CDS             complement(44501..45103)
                     /locus_tag="PC503_000290"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF2526313.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45112..47760)
                     /gene="polA"
                     /locus_tag="PC503_000291"
     CDS             complement(45112..47760)
                     /gene="polA"
                     /locus_tag="PC503_000291"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF2526314.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            47912..47999
                     /locus_tag="PC503_000292"
     tRNA            47912..47999
                     /locus_tag="PC503_000292"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47946..47948,aa:Leu,seq:caa)
     gene            complement(48186..48629)
                     /locus_tag="PC503_000293"
     CDS             complement(48186..48629)
                     /locus_tag="PC503_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526315.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(48632..48829)
                     /locus_tag="PC503_000294"
     CDS             complement(48632..48829)
                     /locus_tag="PC503_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526316.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49021..49887)
                     /locus_tag="PC503_000295"
     CDS             complement(49021..49887)
                     /locus_tag="PC503_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2526317.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(50113..50982)
                     /locus_tag="PC503_000296"
     CDS             complement(50113..50982)
                     /locus_tag="PC503_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2526318.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(51488..51709)
                     /locus_tag="PC503_000297"
     CDS             complement(51488..51709)
                     /locus_tag="PC503_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526319.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(52210..53190)
                     /locus_tag="PC503_000298"
     CDS             complement(52210..53190)
                     /locus_tag="PC503_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526320.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(53354..54226)
                     /locus_tag="PC503_000299"
     CDS             complement(53354..54226)
                     /locus_tag="PC503_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2526321.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANSKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(54390..54941)
                     /locus_tag="PC503_000300"
     CDS             complement(54390..54941)
                     /locus_tag="PC503_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2526322.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(54961..55863)
                     /locus_tag="PC503_000301"
     CDS             complement(54961..55863)
                     /locus_tag="PC503_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2526323.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(55878..58250)
                     /locus_tag="PC503_000302"
     CDS             complement(55878..58250)
                     /locus_tag="PC503_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF2526324.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(58471..59160)
                     /locus_tag="PC503_000303"
     CDS             complement(58471..59160)
                     /locus_tag="PC503_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2526325.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(59401..60780)
                     /locus_tag="PC503_000304"
     CDS             complement(59401..60780)
                     /locus_tag="PC503_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2526326.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(60774..61487)
                     /gene="rgbR"
                     /locus_tag="PC503_000305"
     CDS             complement(60774..61487)
                     /gene="rgbR"
                     /locus_tag="PC503_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF2526327.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(61737..62297)
                     /locus_tag="PC503_000306"
     CDS             complement(61737..62297)
                     /locus_tag="PC503_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF2526328.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(62392..63195)
                     /gene="zupT"
                     /locus_tag="PC503_000307"
     CDS             complement(62392..63195)
                     /gene="zupT"
                     /locus_tag="PC503_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF2526329.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(63346..64509)
                     /locus_tag="PC503_000308"
     CDS             complement(63346..64509)
                     /locus_tag="PC503_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2526330.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGDNPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(64569..65756)
                     /locus_tag="PC503_000309"
     CDS             complement(64569..65756)
                     /locus_tag="PC503_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526331.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66119..67819)
                     /locus_tag="PC503_000310"
     CDS             complement(66119..67819)
                     /locus_tag="PC503_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526332.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68062..68337)
                     /locus_tag="PC503_000311"
     CDS             complement(68062..68337)
                     /locus_tag="PC503_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526333.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(68456..69028)
                     /gene="mobB"
                     /locus_tag="PC503_000312"
     CDS             complement(68456..69028)
                     /gene="mobB"
                     /locus_tag="PC503_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF2526334.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(69012..70193)
                     /locus_tag="PC503_000313"
     CDS             complement(69012..70193)
                     /locus_tag="PC503_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF2526335.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVISDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(70404..71138)
                     /locus_tag="PC503_000314"
     CDS             complement(70404..71138)
                     /locus_tag="PC503_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526336.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            71500..72405
                     /locus_tag="PC503_000315"
     CDS             71500..72405
                     /locus_tag="PC503_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2526337.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(72565..73407)
                     /locus_tag="PC503_000316"
     CDS             complement(72565..73407)
                     /locus_tag="PC503_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2526338.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(73391..74149)
                     /locus_tag="PC503_000317"
     CDS             complement(73391..74149)
                     /locus_tag="PC503_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526339.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(74166..74636)
                     /locus_tag="PC503_000318"
     CDS             complement(74166..74636)
                     /locus_tag="PC503_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526340.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(74636..75379)
                     /locus_tag="PC503_000319"
     CDS             complement(74636..75379)
                     /locus_tag="PC503_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF2526341.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(75383..75796)
                     /locus_tag="PC503_000320"
     CDS             complement(75383..75796)
                     /locus_tag="PC503_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2526342.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(75822..76574)
                     /locus_tag="PC503_000321"
     CDS             complement(75822..76574)
                     /locus_tag="PC503_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2526343.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(76814..78208)
                     /locus_tag="PC503_000322"
     CDS             complement(76814..78208)
                     /locus_tag="PC503_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2526344.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(78228..78437)
                     /locus_tag="PC503_000323"
     CDS             complement(78228..78437)
                     /locus_tag="PC503_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF2526345.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(78466..79911)
                     /locus_tag="PC503_000324"
     CDS             complement(78466..79911)
                     /locus_tag="PC503_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2526346.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            80021..80815
                     /locus_tag="PC503_000325"
     CDS             80021..80815
                     /locus_tag="PC503_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2526347.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            80866..82188
                     /locus_tag="PC503_000326"
     CDS             80866..82188
                     /locus_tag="PC503_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2526348.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(82289..83506)
                     /gene="cdeC"
                     /locus_tag="PC503_000327"
     CDS             complement(82289..83506)
                     /gene="cdeC"
                     /locus_tag="PC503_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF2526349.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(83689..83869)
                     /gene="ssrS"
                     /locus_tag="PC503_000328"
     ncRNA           complement(83689..83869)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC503_000328"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(83984..84895)
                     /locus_tag="PC503_000329"
     CDS             complement(83984..84895)
                     /locus_tag="PC503_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526350.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDYDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDE
                     ELYNINEQESEYNYNEKNTKTRAKKKR"
     gene            85107..85505
                     /locus_tag="PC503_000330"
     CDS             85107..85505
                     /locus_tag="PC503_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526351.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(85628..86644)
                     /gene="ccpA"
                     /locus_tag="PC503_000331"
     CDS             complement(85628..86644)
                     /gene="ccpA"
                     /locus_tag="PC503_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF2526352.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(86897..87097)
                     /locus_tag="PC503_000332"
     CDS             complement(86897..87097)
                     /locus_tag="PC503_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526353.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(87131..87310)
                     /locus_tag="PC503_000333"
     CDS             complement(87131..87310)
                     /locus_tag="PC503_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526354.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(87492..87698)
                     /locus_tag="PC503_000334"
     CDS             complement(87492..87698)
                     /locus_tag="PC503_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526355.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(87746..88171)
                     /locus_tag="PC503_000335"
     CDS             complement(87746..88171)
                     /locus_tag="PC503_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526356.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            88343..88570
                     /gene="acpP"
                     /locus_tag="PC503_000336"
     CDS             88343..88570
                     /gene="acpP"
                     /locus_tag="PC503_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2526357.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(88714..89718)
                     /locus_tag="PC503_000337"
     CDS             complement(88714..89718)
                     /locus_tag="PC503_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2526358.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(89732..90634)
                     /locus_tag="PC503_000338"
     CDS             complement(89732..90634)
                     /locus_tag="PC503_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2526359.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(90829..92004)
                     /locus_tag="PC503_000339"
     CDS             complement(90829..92004)
                     /locus_tag="PC503_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2526360.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(92091..92936)
                     /locus_tag="PC503_000340"
     CDS             complement(92091..92936)
                     /locus_tag="PC503_000340"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF2526361.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(93034..93831)
                     /locus_tag="PC503_000341"
     CDS             complement(93034..93831)
                     /locus_tag="PC503_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2526362.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(93850..94860)
                     /locus_tag="PC503_000342"
     CDS             complement(93850..94860)
                     /locus_tag="PC503_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2526363.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(94879..95661)
                     /locus_tag="PC503_000343"
     CDS             complement(94879..95661)
                     /locus_tag="PC503_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2526364.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(95720..96856)
                     /locus_tag="PC503_000344"
     CDS             complement(95720..96856)
                     /locus_tag="PC503_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF2526365.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(97565..98032)
                     /locus_tag="PC503_000345"
     CDS             complement(97565..98032)
                     /locus_tag="PC503_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF2526366.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(98111..98653)
                     /locus_tag="PC503_000346"
     CDS             complement(98111..98653)
                     /locus_tag="PC503_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526367.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(98705..99391)
                     /locus_tag="PC503_000347"
     CDS             complement(98705..99391)
                     /locus_tag="PC503_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2526368.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(99391..100251)
                     /locus_tag="PC503_000348"
     CDS             complement(99391..100251)
                     /locus_tag="PC503_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526369.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            100386..101186
                     /locus_tag="PC503_000349"
     CDS             100386..101186
                     /locus_tag="PC503_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF2526370.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            101211..101780
                     /gene="yfcE"
                     /locus_tag="PC503_000350"
     CDS             101211..101780
                     /gene="yfcE"
                     /locus_tag="PC503_000350"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF2526371.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(102115..103167)
                     /locus_tag="PC503_000351"
     CDS             complement(102115..103167)
                     /locus_tag="PC503_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF2526372.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(103374..104600)
                     /gene="pepT"
                     /locus_tag="PC503_000352"
     CDS             complement(103374..104600)
                     /gene="pepT"
                     /locus_tag="PC503_000352"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF2526373.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            complement(104690..105742)
                     /gene="ytvI"
                     /locus_tag="PC503_000353"
     CDS             complement(104690..105742)
                     /gene="ytvI"
                     /locus_tag="PC503_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2526374.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
BASE COUNT        33699 a        19231 c        11305 g        41587 t
ORIGIN      
        1 aaaataatta aagataaaag gagtatttta tgaacatact tggattaata gttgaatata
       61 acccatttca taatggacac atatatcatt tatctaaatc tatagaaaaa acaaatgcaa
      121 cacatactgt agcaataatg agtggaaatt ttctacaaag aggcgaacca gctttatttg
      181 ataaatacac tagagcaaaa attgctgtcg aaaatggtgt agacttagtt atagaattac
      241 caactttatt tgcttgtcaa agtgctgaaa ttttttctca tggtgctata acaattttaa
      301 attcactaaa ctgcataaat tctatatgtt ttggtagtga agaaggaaat acagaaattc
      361 tttataatct agctgaaatt ttagcaaatg aaccaaatga atttaagtta cttttaaaaa
      421 aatatttaga tgatggtctg ttatttccaa cagctagagc taatgcactt tttgattata
      481 tacatcaaga caaaaaaaat aattttatac aaaattattc aaaggaacaa ttatcaaaaa
      541 cattaaattc atcaaacaac atactgggta tagaatacat aaaaaacctc atccatttaa
      601 acagtagtat aaaaccattt actatctcca gggtccaatc agaatataat tccgaagaaa
      661 ttgagagtga tatttgttct gctactgcta taagaacttc acttaaagaa aatacagacc
      721 tttttcattt aaaaaatgtt attccagaaa aaacttataa catcctaaat gaaaaaatag
      781 ataatggttt tttacctatg tttgatgact tcttctttga tattttaaaa acaattatac
      841 ttagagatat ggacacttta aaagagtatt ttgaagtaaa tgaaggcata gaaaacagaa
      901 tctataaaga tatctttaca tctgaatttc tacatgaact acaattagca attaaatcca
      961 agcgatacac tttaaccaaa atcaaacgaa ctctaaacaa tatattgtta ggtattaaaa
     1021 aaagcgacgt gcaacttata aaaaacatag atactatacc ttatataaga atacttgctt
     1081 ttaatgataa aggtagagaa attctaaaag agataaaaaa taaatctgaa ataaaaataa
     1141 taaacaagtt ttcaaatata tcattttcat tagatgatac gatttttaaa acactcataa
     1201 gttatgatat aaaagctaca aatatatata attcaatata ttataaaaac aataaagatt
     1261 tagtaaaagg ccctatggat ttttatactc atccaatata tgtaaagtag ttttttaaaa
     1321 taactatatt tataaaaatc attttattaa ctctttatta tataagatac aatagtctta
     1381 ctttatttat gtacacatgc ttttaggatg acaacatcaa cttaaatatt atgttacttt
     1441 ctaaatttaa gtaaatattg ccatcctaaa aattttacaa tttagcttca gatttaaaag
     1501 taaagtttaa aatattatat ttaaatctaa tttaatattt tttgttttat aaatattatt
     1561 aaattaatat ttctaatata ttttccctgg atttaaaata tttttagggt caaaagctaa
     1621 ctttatattt ttaattaaca tcatataagc atctgaattt gattcatgta agtactcttt
     1681 tttagcatat cctatgccat gttcaccaga aacttgacca ctaagttctc tagatttttt
     1741 atacatatag tcaaaagttt cttttaatct tattttccat gtattatcat ccataccatc
     1801 ttttaaaata tatatgtgta gatttccatc tcctgcatga ccaaaacttt ttattcttat
     1861 ttttaatttg tcttgaagct cgtgagtgta tcttataaac tctgctatct tatctcttgg
     1921 aacaacgaca tcacattcat ccatttgtgt cgtagatgcc tttatagctt ctaaaaatgc
     1981 acctctggct gaccatatag aatcgtttct ttcttgtgta tctgatataa atacatctaa
     2041 tgcaccattt tctaaacata aattagctac tttttcatat tctttttcta tatcttcagt
     2101 gctatttcca tcaaatgtaa gcaaaagata agcatctgat gtattatctg gaaacttttt
     2161 acctaaaaat tcttctgctg ccaatatcac atctctttcc ataaattcta tagccgttgg
     2221 tattgatttt gattttatta ttttaggaac agtttctatt gccattgata aatctggaaa
     2281 tggtataagc aaacttatac ttttctttgg taaaggaagc aattttaata tagctttagt
     2341 aactattcct aaagtacctt ctgagcccac taataaatcc tttatactat atccagaact
     2401 atttttaacc acctttccac ctacatttat aatttctcca tttggtagta caacttcaag
     2461 tcctcttaca taatcccttg taacgccata ttttactgct ctcataccac ctgcattagt
     2521 gtttatatta cctgcaattg tagcactttt ttcacctggg tcaggtgggt aaaataaatc
     2581 tctatcttga acatattgac ctattgtcat caataaaaca cctggttcta ctgtcaatgt
     2641 taaattttca taatcaactt caagtatttt attcatttta catagattaa tcattattcc
     2701 accatttatg gcaacagcag cacctacaag accagtacct tgacctcttg gtgtgactgg
     2761 tatattattt ttatatgcgt atttcattat tttagatact tgttcagttt caagtacatt
     2821 tactaaaact tcagggtact tctcaatccc tccaagttca tcatgtgaaa aatcttcatt
     2881 tatatcactt ccaactaata cattttcttc tccacaagta tctattaaaa aatctatatc
     2941 ttttttatcg attaatttat acatttctat ccccctattt agctgctgat gccatatatt
     3001 tttgattatt atctttgtta ttttctattt tttcaatcaa tttaggaata atatcataaa
     3061 tatcacctat taaagctaaa tgtgctacat caagtatagg cgctttatca tctttattta
     3121 ttgctactat atagtcagca ccctgcatcc ctgcaacaaa ttgaactgct ccagatacac
     3181 cacaagttat tatcaattta ggttttacag ttctaccact aagacctatt tgttttttag
     3241 catctatcca acctgcttct attacaggtc ttgttcctgc cacttgagcg tttaacttat
     3301 cagctaattt atatatcatc tccatatctt cttgtttttt tattgctcta cttgccacaa
     3361 ctatcacttc agcttcttcc agaccaactt ctttattttt ttcttttaca ctcagtacct
     3421 taattttaga ttttagttct tttttttcta ctttacataa agttatcttt cctgtagtat
     3481 tctctatttt ttctggtgct gaaaatattt tatatcttac agtggcaaat tgtggtctat
     3541 tattaggtgt gtttatatga gccattatat ttccaccaaa tgctggtctt atttggtcta
     3601 aatcagtatt tgattgaata tcaagtattg tacaatctgc tgtaagacct gttctaaatc
     3661 tagcggcaag tcttggagct aatgacctac ctaatgtagt tccaccaact aatactatcg
     3721 ttggttttat tttatctata aagttttcta ttgcttttga atatggttct atcctaaaat
     3781 ctttaaattc atcttcatca tatacaaata cttcatccac cccataagaa atcaaattac
     3841 tgcacttatc ttttatgtct tttcctacaa atacacaata cacaggttgt tttatttttg
     3901 atgccatctc acgagcttta cctataagct cgtacgttac aggatgtata tttccattat
     3961 gatgttcaac atatactgca attcccctcc attcatcttt attaatttgt actttactac
     4021 tctctataaa ttcaaatgcg ccttttggtc cacttttgac acacaacttg cacatcttac
     4081 agccagcact tatttctact atacctgact tttcttctat agccccaaaa ggacatattt
     4141 ctaaaattct ctttaagtca gttattttat cttgatttac aactatcttt gacatttatt
     4201 actccccctt acaccaactt taattcctct aatttattta caagtgcaaa acttagttca
     4261 tctgcatttc ctcttacaat atttttatct gtatttggct ttggaggaaa tattcttaca
     4321 acttgagtag gagaaccatt aagtccatag ttattttcat ctttatcttc aaagtcatct
     4381 aagctatata caggtatttc tctatcttta gtattaagtt ttaatttaaa tgaaggtagt
     4441 cttggttgaa aaatgtcttt ttctacagtt attaaacatg gatattcaat ctcacatact
     4501 tgtaaatcat ttggcatatc tatttcaaca actatacttt catctttaac ttcaattaat
     4561 tttgtaacgt tagtaacatg aggtatatct aaaaattcag ctacttcagg tcccacctgt
     4621 gctgtatcac catcagtagt ttgttttcca caaattatta ggtctacctt tcccatcttc
     4681 ttaatacctt gtgatatggt ataggaagta gccaatacat ctgctcctcc aaatctccta
     4741 tcacttatta atgctccttc atcagctccc atcataaaac tttcttcaat taccttcttt
     4801 gcctgaggag gacccatgct aagtactttt agattcgctt tcttatcttc ctttattcta
     4861 agagctgttt ctaaagcata taggtcatag ggattcattt ttgaatctac tccatctctt
     4921 tttagtactc ctgtagtttc atcaacttct actgaagtcg ttccaggaac ttgtttaata
     4981 catgtcaaaa tttccataaa gtacactcct tttttattta actataactg atactccatc
     5041 aggtataact actactttgc tctccttacc aactatacta ttcgccattt ctaaagcttc
     5101 tttaaagtta aatgcatgtt tcatatgcat tttttttatc atttcaggat tacacttatc
     5161 tgttaccatt atcacagtat atttagataa tattctcgct agtatctgaa attcccattg
     5221 gtctggaatc gtatctactc tatcgacact tctaatttta tctaaaagtt gttttggaga
     5281 atctgcattt gctacatttt cataaaaaga ttgacctcca tgaccatcat tacatgctga
     5341 aatcattatt attactccac cgtctttaca agtagcttca gctgctgtca ttcctttaac
     5401 agattgataa atattttggt ctagtggata tccaccattt gtagttacaa caatatcaga
     5461 ttttatagaa tttacttttg ataactctgt tacaaatcta catcctttag tatgtgcttt
     5521 ttcgacatca ccagcaaagg aagcaattat ttttttatct ttatctatta caacattcaa
     5581 tatgaatgct aattttgcaa ctttagctgc atataccata tcctcatgaa taggattatt
     5641 attcaatttt ccagttcttg aattatcact atctataaag tcactacaat gattgtacat
     5701 tatagtcttt gcagatgcga ttcctggaag tacacttttt ctgccacctg aaaaacctgc
     5761 aaagaaatga ggttctataa aaccttctgc tatcaaaagt tctgcctcat atgctagttt
     5821 gtttatatat aaatctccac ctgaaggcaa tatccctact ttacacatag atttatcatc
     5881 agtagatata tgcataacta tatcttcatt atctactatt tcttctccca ttttataaat
     5941 tagctcttcc cttgtacttg gcctatgaaa tccagttgcc actataatct tcacatcaat
     6001 ttctggatta acattcctaa tccttcttaa tataattggc atagttattc tacttggtac
     6061 aggtcttgta tggtcacttg taattatgac tacattcttt ttccccttaa ccagttcttc
     6121 cagagaatta gagcctatag gattattcat agattcttca actatctctt cttgagtctt
     6181 atgttctata taattatccg attttgactc caaaacaccg agaaaacgtt catcaggtat
     6241 ttctaaaatc attccttgtt ttgaatacgg tacttttaac tttaccattt ttaatctccc
     6301 attataataa actataaaat tggtatgtgg tcataccagt tttacattta tatgatagta
     6361 ccattatcta ccatttgcaa gaataattta ttttataaca aacttttaat tttcattttt
     6421 tctataattt ttacttataa aatccatatg ttcctttgct ttctcacatg caagttctac
     6481 atcattttct acaactgcat tgtatatagc ttcatgctgt ttaagcaata tattttcatt
     6541 aaaaggttct gcgattattt tttctcttgc atcttctata aatccatcaa ataattttga
     6601 tgctgtcata aaaagacttt gaattaaata atttttactt aatgttgcta gtttactgtg
     6661 aaatttttgg tctaataaca ccagtactcg attattatct tttttattag tttctaccct
     6721 catttcatct attatatgtt tcaattctat aacttcagaa gaagttattc tctttgaagc
     6781 aagttttgca atctcaattt ctaggattat tctaagctct aatatatctt caagtgtacc
     6841 attattaagt ttaaaaatca tagataaagg ttctattaaa gttttttcta tatttgtaca
     6901 tataaaattt ccttcaccct gtctgctttc tatcactccc atagtctcta ataccctaat
     6961 agcttccctt atggaagttc tactcacatt catttgttca gacagttctc tttctgatag
     7021 taatttatcc ccctttttta actctccatt tagtatttta tattgtattt gctcaattac
     7081 ttgttcataa acttttttac tagctatact attaaacatt ttttcctcca atatgataat
     7141 cgttgttgta atatatatct attatatatc ttaagccatt acattcatat atttttatta
     7201 cttttaatat aatatcttat aactcaaatt tacaggtgat attatgaaaa aaaataaaat
     7261 tattgctttt tttgctccat ctatcatagt tggagttcta gttttaggga ttatcctata
     7321 cccaaatgaa gctataaaat ctgcaagaga aggcttttct atatggtcta atgttttagt
     7381 tccatcacta ctaccattta taattggagc aaacttaatt gttgatttaa aaatagtgga
     7441 tattataggg tttatcatca atcccataac tagatttgta tttaatgttt caggaaagag
     7501 cgctttagct tttgctatat ctacagtatc tggttatcca gtaggagtaa gtttagcttc
     7561 tgaatttagg agtaatggac aaatttctaa gtatgaagca caaagacttg tgtctttttg
     7621 ttctacatca ggacctttat tcataatagg ttcggttggt acaggtatgt tccaaaattc
     7681 aaacttaggt tatttaatga ttctctgcca ttatctagga actatattgg ttggtctttt
     7741 ctttagaaat tatggtaatg aaaatcttcc aaagacaaaa ttggatttaa aaacaaatat
     7801 aaaaaatgta atcaacatta gaaattcaag tgggaatggt ttttttgttt tatttggaaa
     7861 tgctgtattt aatggagtaa atacattact tacagttggt ggatttgtaa ttgttttttc
     7921 agtagtattt aaaatactat ctctttttaa tgtaatctca ttaatagcat cagttatata
     7981 tttgcctctt tcatttttag gtgttagtaa agaactctgt caagcatttg taagtggtct
     8041 atttgaaatt actataggat gcaataaagt atctagtata acaagttctc cagaaatttt
     8101 aagagcatct ttagctagtt ttttgatagg atttagtgga ttatccatcc tagctcaatg
     8161 ttgtacattt ctatcaaaaa cggacataga tttaaaatta tacatactaa gtaaatttgc
     8221 gcatggagtt ttagctgcta tctttatatt tatactttat ccaattgcaa actctgctgt
     8281 gttggtttct agctttgctg atacatacaa cgttatatat aataatttaa tctggtttta
     8341 ttatcttagc tattatgata caattcttca aattgtagta ataatttatc taatctcagc
     8401 cgtatttatt gcaaaaaaac atatgaaaac tttatctaca aatgggaaac taatgcgata
     8461 taaaaatact tttttcacta agaaattttc acgaaaaaaa taaaactaaa aataaaacta
     8521 ataaaactta actaaatact tccatttttt tattatattt gtcataattt taataacctt
     8581 tttaattagt ttaacagcat agttatttca tcacaattta ataattttat tagaaatatt
     8641 tttcaaaaaa ttctccttaa tcacatatat cacacttgta taagtttact gggaaatttt
     8701 tccattatat aatatttcat ttatattata taataaatac cgacctaaac ttaccaaatc
     8761 aaactaagag gagtggttga aaatggcaac aagacctata gaaatagacg aatataaaaa
     8821 gataatggaa ctattacata ctggctttac ttatagtgaa aatggcgttg aaaaaagatt
     8881 tagaaaaaat cctaaagttg cattggcact aatgttagaa gctaatttag gtctaagaat
     8941 atcagatatt ttaagattaa agataggtaa ttttaaaggt aatatgttgg aaataaatga
     9001 aaaaaagacg ggcaaattac agtatagacc agttaataaa aatataattg agtccataaa
     9061 tgaacatgca agaaagtata atcttaaatc aaatgactac ttagtaaata taaagacaaa
     9121 ggctattcaa aaacagttga ggataatttg taaatactta aatctgtata atataagtac
     9181 acatagcttt agaaagctct atgctactac tcaatttgaa aagagtaaca ataatttaga
     9241 gttggttaaa gaacttttaa atcacagctc tgtagccact acacagcgat atataagggt
     9301 aactcagcaa gctattaatg aagctagtga aaatttcttt attggttaat tataacgtat
     9361 acatttttct attatcttat taattcacca gatattaaaa aagagtgtct caaaatgaac
     9421 tttttagttc atgagacact ctttttttat aaaatcaaat atatttttat tatttcaaca
     9481 ctggaaaaaa ggcttatctc tctattttga gacaccctat taaattttca taattcttgc
     9541 ataaacatat taatctatct tcaataattt tttagctgat tcactgtaat tatttctttt
     9601 tacaatttcc aaaactctat caatctcatg ttctgacttt gcacttacaa aaatcgccaa
     9661 ttcttcatca tctataatat cataactatc tacatattta tctaaacatt ctaaaattcc
     9721 atctttatta ttatacccac caaatctaac tactgcacta cactcatctt ctataagtcc
     9781 acttaaatcc aatttccctt ttgaaaaaga ctttatattt gaacttctat tatctattat
     9841 atctataata tctgcataaa cagcacttcc tgttgcacct cttccagctc ccttacctac
     9901 aaaagaaagt tcacctactg aatcacctac taaaataact acgttgaact cattatctat
     9961 ctttgaaagc atattattat tgtccactaa tgctggtcta acaaatccac ttacttctcc
    10021 tgattcatac ttacttctag caaccaattt tatcttacaa tttaattttt ttgcatattc
    10081 tatatctttt tcatctattg aagttattcc ttctaataat aaatctttcc aatatactat
    10141 ttttccataa gataaagtag acaatataga taactttcta gcactatcat atcctaaaac
    10201 atctgcatct ggattaactt ctgcaaatcc caactcttgt gcctgtttta aagcgacatc
    10261 atacggtaaa ttttcatcat acatctttga taatataaaa ttacaagtcc catttaaaat
    10321 agcgtttatg ctctttatat tgttgccttc cagtgattct atcaatggtt ttaaaactgg
    10381 aataccacct gccacagatg cttcaaactt gatgctaaca ttatttaagt tagctaattc
    10441 tataaggtca ctaccttttt cagccagtaa atctttatta gctgtcacta catgtatttt
    10501 tttatttaac gctcttgtta cataatcaaa agctggattt aatcctccaa ttacttcaac
    10561 tagtatatca atatccttgt caaatatatc ttctatatca gtagttatct tatcaaaata
    10621 cttcttatac ttgtgttttt ctttattttt aactaaaatt ccaacaactt ctatatctct
    10681 ttttgaagta ttattttcta ttaaatcaat taatccactt cctactgttc cataccctaa
    10741 tattgctatc ttcactgtaa cataccccca tcattttgat tatattaaat tatttatata
    10801 tataaatata ccaataaaaa aagcttgagt ataaactcaa gccatatgac gggtttatac
    10861 tcatctttca gcataaatgc tgcaggattt agcaccaatg tataattaaa tatactggtt
    10921 gccgggcttc acagggccag tccctctgcc actcttgata agattgctaa tttaaattta
    10981 tgtttaatag tataatacaa tttcttccaa ttgtcactat ttttttaact tatttcccta
    11041 aaaggatata aactattatc taacagctct tttagttggt ttaccctttt ttgtaacatt
    11101 attattttta gtctttgctt tcgcctgttc atgtcctgga aaaagtattt taggctcttc
    11161 aatattcctc ttgtaaatag taaatttaaa accaatagcc tgcacaaatt cagctcttaa
    11221 agcttcacat actgcattag cagtttcttt agtatcaaga cctgcatttt ctaatatagt
    11281 aacttttact aattctctag ttcttaacat accatctaat tgctctaaga aactctctgt
    11341 aacaccttct ttaccaattt gtgtagtagg ctttaaagta tttgccaaag atcttaaata
    11401 cgccctttgt tttcctttta acatattctc acctctataa ttctatactt aaattatcta
    11461 taatctatat ttaaattaat tgtaaaactc aaattctaat tcataaattt taaccacatc
    11521 tccatcttct attcccattt ctctaagcct atcaaaaaca ccttgactct ccatagcttt
    11581 ttggaaatat tgaagggatt ccatatcatc aaaatttaca gaatacatta ttcttctaag
    11641 tgctttacct gtaactacat acacaccatc ttcaatatct atacttaact cttcttcagt
    11701 accaatatca agttctggtc tatacatttc ttcttctgaa actagctcca catcttctac
    11761 ttcttttagc attttagaaa cataggctat tacttcatct atgccttgac gagttgctgc
    11821 tgacatttta aatactgtat atcctctgcc ttctaattca ctcttaaact tctcaaactt
    11881 actctcatct tctaatatat caaatttatt tgcaactaca acttgtggtc tctttgaaag
    11941 cttttcattg tacaatttaa gctcatcatt tatcttgtca aaatcttcaa tagggtctct
    12001 tccctctaat ccagatatat ctacaatatg tatcaatacc tttgttctct caacatgtct
    12061 taagaactca tgacctaatc ctatgccttc agaagcaccc tctataattc caggtatatc
    12121 tgcaagtaca aaactatctc caaacttagt ttgaacaaca cctagatttg gtgtaagtgt
    12181 tgtaaaatga tagtttgcaa ttttgggttt agctttagtt acaactgata gaaatgttga
    12241 tttacctaca tttggaaatc ctaaaagacc aacatctgct atcattttaa gttcaagagt
    12301 tatccatctt tcttctccat ctgtaccaga ttttgcaaaa gctggagctt gtcttactgc
    12361 atttgcaaag tgttggttac ctttaccacc tataccacct tttgcaacta tagctgtatc
    12421 tccttctttt tttaaatctg ctaatacaag acctgtagcc tcatctctta ttactgtacc
    12481 tgctggtact tttaatacta aattttctcc atttttacca gctctttttc ctttgcttcc
    12541 gtcgccacca ttttgagctt gatatttttt ctggtactta aagtccatta gagttctaag
    12601 ccccaaatca acttcaaata tgatgcttgc tccacgacca ccatctccac cgtctggacc
    12661 accagctgga acgtattttt ctcttctaaa tgctaccgaa ccatttccac catttccagc
    12721 cttaacaaat attcttgcct tatctataaa caaattcttc acctacttaa ttaaaaactt
    12781 ttaattagca ttaccaaaaa taccattata aattcatcag tattataaga aaaaggagtg
    12841 cctcaacact ccttttatgt atattactca gctattgcta ctggatatat actaactttt
    12901 tttctcttct tgtcttttct ttcgaattta acagtaccat caactaatgc aaataaagta
    12961 tcatcactac cttttccaac attagttcct ggatgtattt tagttcctct ttgtctaact
    13021 attatacttc cagcagttac taattgacca tcgaatctct taacacctaa tcttttagat
    13081 atagaatctc taccattttt agaagaacct accccttttt tagatgctaa taattgtaaa
    13141 ttcatgttta acatatggag tcacccccta cttttttaaa atttttatat tttttgggta
    13201 ttcccgttta atttctttaa ccgctaattg aaagtgattt agtaataatt gtgcgtcttt
    13261 tacatgtgta tctttgacta tacactctat atgaccttct tctcctacta ctttttcaaa
    13321 ttcaatcttc tgtaatttgt ctaaagaatt tataactgca atagcattag atgtaactgc
    13381 agcacatact atatcatagc ctatttcagc aaaatcagca tgtcccttta aacaaaaacc
    13441 ttgcaacaag aaatcatcat tataataata tttaactttt atcataactt aaccaataac
    13501 taagcgttta ttttttctac aactatctta gtgtatgatt gacgatgtcc ttgttttctt
    13561 ctgtaatctt tttttgcttt atacttgaaa actataactt tcttagcttt accttgttca
    13621 acaactttag cttgaacaga tgctccttct actactggag aacctaattt taattctcca
    13681 tctttagagc aagctaatac ttcgtttaaa gtaacaacat cacctgcgtt agcttctaat
    13741 ttttcaacga ataatacatc accttcagaa actttatatt gctttccacc agtctttact
    13801 atagcgtaca ttaaatacac ctcctcggcc tcaaactcgc cagtacaagg tacttcattt
    13861 gaagatttaa acctttactg tgcggcatta caattattaa ttataaaata tttacatttt
    13921 attgtcaact attttatcga aaataacatt ggttttattg tgctttaatg tactatttgc
    13981 gtttaaagaa atctttatat tatatttttc accaatttta tcaattatat ccatataata
    14041 ttcttttatt tgttcaaaaa taaaatcatt aaattctacc attatgtttt tgtaaacagt
    14101 atgttcactt attctcataa tttctttttc aatactatct agtatataat gtacagattt
    14161 tattgtttgt tcaccatcac aacatggaca agacattaaa taatacttat caatggattc
    14221 tttttctcta cgcctagcaa cttctactaa accaagtttt gtcataccta atacttcagc
    14281 ttttctttta tctttattaa attcttcttc taggatgtgt aaaatctcct tttgatgctt
    14341 ctttttatgc atatcaataa aatcgattat tattatccca gctatgtctc taattctaag
    14401 ctgtcttaca atttcttttg cagcttcaag attagtttta taaacggttt catcaagttt
    14461 accagttcca ataaacttac ccgtatttac atctataacc gtaagagctt ctgttttttc
    14521 aattattaaa taacctccac tctttaacca tactttttta tttaataatt tttctatttt
    14581 agattctatt ctgtataaat caaatacatc tctattttcc tcaagacaca gtttatcaac
    14641 ataagtctta tctatacctc ttaaaataga cttaagttca gagtacttat cataactatt
    14701 ggtaattata gattcaatat catcattcac attatctttt acatatttag ttgcaaaatc
    14761 taaagactta tataataatt tcggacctat accaagttta tattctttta aaatgttttc
    14821 atactttaat ttcaactctt ctatatcttt ctttatttca tcatgagtgc aaccttgagc
    14881 ctcagtcctt attattaatc ctagattttc cttatttact gccttagtaa ttttttttaa
    14941 tctaaatcgt tctttttcat cagtaatttt atttgatatt gtagttctat cattggaagg
    15001 tatatagaca atataccttc cagaaatact aatctcagtg tttaattttg cgcctttagt
    15061 tcctatttct tctttattta tctgaaccaa aatatcctga ccagatttta tagtacttcc
    15121 cttttttaat tgtaaataag caagtttctt aaatccaata tctacaaaac aagcttctat
    15181 tcctggtata acttttttta cgattccacg atatatattg gatacagtct tcttatttaa
    15241 attgtcttca acaaaaagtt ctgttaatct ttcatcttca agtactgctg ttttctggga
    15301 ccctattagg gactcaataa ctatcttttt cacaacttca cctctcgagc ttacatagga
    15361 gtcactaatt ccccatcttc taatacatat aaatctcttc tcaatatatc aacatctaat
    15421 gggtcaatat caagttcaaa catctctaat atctttggta taagtatatt agtatttaaa
    15481 ttagtttttg agcctgtagc tatagtagca gtaagagtaa tatgttcatc ttctaaattt
    15541 aaaacatcaa aggttcttat cataggtctt atatctactt caaccatctt acctttttta
    15601 ttcttttttg ttatgattat ttctttatta ttcataaagt caattacttt tctttttaca
    15661 aactctttcg tcataggtct tttcaaatct atattaaaca aatattctcc atagtctatc
    15721 acagaagaaa gagaaggtgt ttgtctatca atttcttttg ctttgataaa atctatccca
    15781 tctggaagtt gaattgatac tttatttaaa aattcctcta ctgataaatc atcttcttct
    15841 atttcaatat ctacatactc accttgactt tctgccccta aagccaaagc attgccataa
    15901 ctcattttag ggtgaggatt aaatccttga gaatgtgata agtttatttc agctcttcta
    15961 aacgctcttt gtaacaatct ctgaaggtca agatgtgata tatatatcat gtcgccttcc
    16021 tttttaaatt ttactcttat tatcttactc atattagcaa agcccccttc ctatatcatg
    16081 tatatttatt ccacaaccat tgcagttatg tctacaatca gaagtgattt tttctttttt
    16141 agcattttcg tcttctctaa ttaagaattt tttactaata cctacatcta tatggtccca
    16201 aggaaatacc tcttcatagt ttctatttct atgtgcataa aaatctatag aaagattatt
    16261 cttttccata gcttctttcc atatatctaa attaaaatgt tctgcccatc catcaaattt
    16321 agcacctagt ctaaatgcat catatataac ttttcctatt cttctatcgc ctctagctac
    16381 tactgcttcc atcaaactag tctttgaatc atgataattg tattttatat tgttatttct
    16441 taatttattt actaaatgtc tctgcttatt aataacttct tctgtagtat cttgaccatg
    16501 ccattggaaa ggtgtaaatg gctttggtac aaatgtagaa gtactcactg taacactaaa
    16561 acttctcttt agctttcctc catttacttt tctataaata tcaataactt tataagccaa
    16621 tttagctata ccatctaaat cttcataagt ctcagttggt aaaccaatca taaaatacaa
    16681 cttaacacta ttccacccca tctcaaaagc tctttctgtt gcattttcca aatcttcttc
    16741 tgtaacacct ttatttataa catctctaag tctttgagtt cctgcttctg gagcaaaagt
    16801 aagtccagat tttcttactt gttgtatttt atcagcaatt tccattgaaa aattatctaa
    16861 tctaagggat ggaagcgaaa tcccaatatt attagatgca tattcatcta ccaaataatc
    16921 agtcaactct gataacttac tataatcact cgtactaagt gatgataatg atatttcatc
    16981 atatccagta ttcttaacta atttatctaa tatttcttta agtcttttaa cactcttttc
    17041 tcttattggc ctgtatatca tacctgcttg acagaatcta catcctctag tacatcctct
    17101 aaataattct agtactattc tatcatgaac agtatctata taaggtacta ttagtttttc
    17161 tggataatct acagtctcaa catcttttat tatcctttta gtaggatttt tagtaatccc
    17221 ttctctatta ggagttacac tttgaactgt accatcttca ttgtacttga catcataaaa
    17281 acttggtatg tatactcctt ctatgctaga tattttatat aaaaaatctt ctctagtcgt
    17341 tttatttttc ttccattctt tatactcatt tactacttct aaattaacct cttcaccttc
    17401 acctaatatt actacatcta caaaatctgc taatggttcg gaattataag cacaaggacc
    17461 accaaccatt ataaatgggt cttccaaagt tctttcttct tttaatattg gtatattggc
    17521 taaatctaat atatttaaga tattagtgta tgaaagttca tattgaagtg taaaagtgac
    17581 aaaatcaaag tttgttatag gctctcttga ctctaatgca aataatggta tacttttttc
    17641 tctcattata ttttccatat caactgcagg agaatacact ctctcacaaa atacatcttc
    17701 atccttattt attacatcat ataatatatg actccctaag tgactcatac caacttcata
    17761 taaatctgga aagcaatgtg catatcttat caattcacta ttactagtat ctttatgaat
    17821 tgaatttatt tcatttccaa gatatctagc aggcttttct acttttttta agattttttt
    17881 caagtctact ttattcattt attaaaattc ctccaaacaa gctctttatt tttattctta
    17941 tttataagta atattataca cgataaaata ttttctatca aaaatataac taaaatattg
    18001 aatttaaaat acatattatt cacaaaatag aatagctaaa aatatttaag aatattttct
    18061 attaaatttt tattgaaata caattttttt acaaagtatg atatattata aacataaaac
    18121 tattgtttta catgacttat catgacatct tttgtttcat tcacctcaaa atggggtatg
    18181 ttacttatat aatgataaat tttaggaggg ttaaaaatga gtaaagtttt tgaagtaaaa
    18241 aaagatatct actttactgg agtagtagat gaaggtttaa aagtattcga cataataatg
    18301 gaaactgagt ttgggacaac ttacaactct tatttaatca aggacgaaaa aacggtttta
    18361 tttgacactg taaaggcaaa ttttaaagat gagtttttaa gtaatttatc agaggttact
    18421 gatatagcta aaattgacta tgttgtaatt catcacacag aaccagacca tgcaggtagt
    18481 ttaaaatact tattagatat aaatcctaat atagaagttt attgtactaa agctgctaaa
    18541 ctatacttag atggtcaaat aaatagacct tttaactgtc atgtaataaa agatggtgaa
    18601 attttaaata tcggtaaaag aaatcttaga tttataactg ctccattctt acattgggtt
    18661 gatacaatgt ttacttacat tgaggaggac aagactcttt taacttgtga tgcatttggt
    18721 tgtcactttg caagtgttga tgcagaggta gtgaatagtg aagattatct aaaatcagct
    18781 aaacactact atgattgtat agttaagcca tttgctaaac atgttttaag tgctgtagat
    18841 aaggtggtag gactaaacat agaatttgat actatattga cttctcatgg tccaatgctt
    18901 actaaagacc caatggctgc tgttaaaaga tatgttgagt ggtctacaga agctgttaat
    18961 acaactaatc aaaatcaagt ttctatattc tacttatcag cttatagtaa tactttagag
    19021 atggctaaaa agataaaaga aggacttgat aaagaaggtg caaaggctga attatatgat
    19081 ttagaagata tgacattaac agaaatgcac gatacattag tagtgtcaaa agtaatatta
    19141 ctaggctctc caactataaa caaaactatg gttaaaccta tgtgggattt attctctgtt
    19201 atagacccaa tggctaacca aggcaagata gcaggagtat ttggttcatt tggttggagt
    19261 ggtgaaggta taactatggc tgagacttta cttaaatcta tgtcattcaa aatgcctgta
    19321 gaatctctta agaaaaaatt cttccctagt gaagagacat taaaagagtg tatggcattt
    19381 ggtgcagaat ttgcaaaatt agttaaatag ccattaatca aacataatat tatttaaaat
    19441 aaatgatttt atatttaaaa ataaattaaa atggagttgt ctcaaaatta atttttctaa
    19501 tctaatttta agttcaactc cttttttatt ttccaaaatg actaatataa taataaatgt
    19561 accctttcgc acagggtgca ttatttatag tctgttctat ttgtatacta gtatacttgt
    19621 attaattcac gtatctagta tatgctacta gccctattcc agaattagat gttgtttcac
    19681 caatttctac tttaataatt atattatttt tttacacttt tttgataatt ctgctgcaga
    19741 aaggttctta ccagtaaaat ctaaagaaaa tgccttatca tactcaaaag gataactaac
    19801 aggtttgctc tctggtgcta atgcaaccat accatatggt gtattcataa accctattac
    19861 agtaactgta tgctttgatg ggtctaaatt tgaatttttg cttgtaaact taattgtatt
    19921 tattgatgag ttgattaaac tacacggaac tccctcatac atttcaattt ttggacgtag
    19981 attatttcca taaacttcat caagtattgc cccttgttga tctgctatca tagtgtgatt
    20041 cccaggtcca actggcgcag aaggcttagc tggcgtaggt ttcttaacag ttggcgttgg
    20101 attctgtgtc tttactactt cgccaacagc tggatatgct ttcttgtcaa atggtaatgg
    20161 gtgagtaaga ctcttgtata tgatgtctgc tcctgctgat ttgttggcat caatatctac
    20221 atgatacaaa cgtccatcct caaaacgaat aagattccac tgatggtcat ttgttgtact
    20281 atgtacataa taacattcaa ttcccatagc atcacataaa gctttcaagc tcctacacat
    20341 tccagaacaa gcaccttttt tagtaaccaa tgtataagca gtattggctc cctctgctgc
    20401 gttccagtta acatatgttg tgttgttttt aatgtgatta tgtatagata caatccacta
    20461 tggagaaata taaaagaaaa gaatataaca aacaataaaa aataagatga ttcaaatttt
    20521 attttgaaac atcttattta ctctacaaat taaaattatt tggtgaatta tttaattatt
    20581 attttttatt aaagaaattt taaatcttaa tataaaatac gctattatac ataataatcc
    20641 aaatacgaat gctactggaa ttaacatctc cgattcaaaa taaaagaaat attctaagaa
    20701 aatatctgga tttactatat tcccattctt gtctaaaaaa tcttttccat tatatcctaa
    20761 atgctgtata aaattactta tgttattata atctgcttcc ctctcatata ccatattagc
    20821 attcaatcca gaagaactta aattagtgtt tccatctttc atatctatta catatagtct
    20881 aagagctttg actttactat acttatcttt atcaagtatt ttttcaagtt ctaacttata
    20941 ttcaccaatc tttgtcatat catgtctttc tgccaattgc tttatttctc catcaagttc
    21001 ttttcctaaa ttatacatat tatgttgtaa actattattg taataccaca taaatccaga
    21061 aattaaaaat gcaattatac ttatgtaacc taatactttt ttaaacccca ttacaattga
    21121 tttatgccta tccaatgata aagatagttc ttttattata ttacataatt catactgcat
    21181 ttcatcacca tcatcaaatc tttcaattgc ttttttacat gcttcttctt catctaatcc
    21241 ttctaattta aattcatttg cagattctat aagatggcat ctcatttcct gttttaattc
    21301 tatagtactt ttattgtcac attttttata tagtttatct aaatattcat ctattagttt
    21361 cataaattaa tccacctctc ccaaaaattg attcataacc tttttaataa atctccattc
    21421 ttgtttcttt atttctaaaa aatctttacc ttcattagtt aaattataat attttcttct
    21481 tccacctgaa ctttgttcat tgctataata agatttaatt aaatttttag attccattct
    21541 tttaagtgca agatacattg ttccttcttt taattcaaac tcacttcttt ctcttacttg
    21601 ctttgcaatt tcatatccat aacaatcttt cttttctaat atagaaacaa ttaatatatc
    21661 gatataacct tttaacactt ctttatttaa ctgcattatg taccaccgcc ttttcaccta
    21721 ctactctata atgtatagta cttatattta ctataatatt acatagtact ctataataca
    21781 aggtttatat tctacaatag acttaaaaat aataaatagc tgtatattaa tatttaatct
    21841 ataaatacta atatacagct atttatcaaa ttttaaaaat aaatttttgt tttattaatg
    21901 ttgtcataac aacatttact tggttgaaat agtattacct ataagtttaa atatatataa
    21961 taatagactt gattctattt catattatta aaatagagta atagtttaaa ttctactact
    22021 ctatctataa tctatttcct aattatttaa tctcaaattt agctcttcat catttaaatc
    22081 tttcataaga tttctacagg tactagattt attccaacag aaaaactagg gcattaaaca
    22141 cttatatatc tgtttcttta gactgtaata ttaatatttt ttaaatacgt tgacttttgc
    22201 tttttctaac ttctctccat gatagttctc ctctatcaag agcttttata aatatttctg
    22261 ctgaagctag atttgtagct attggaacat gataaacatc acaaagtctt attaacgctt
    22321 gtatatctgt ttcatgagcc tgagatgtca atgggtctct taaaaaaata actaaatcta
    22381 tttcttgtgt tactattaaa gaacctattt gctggtctcc acctaaagga ccagatgcta
    22441 atctatttat atttaattca gtttcatcca ttattctttt tcctgtagtt ccagttgcat
    22501 atagtccata cttttttaaa attgattcat aacctataca aaatccgacc atagtgtttt
    22561 tcatttggtc atgtgctact aatgctatat tcatatatct aatctcctca atttatgttt
    22621 agatgtattt aaatttagaa atttattttc tttcttctca tacacacatt tagtactaat
    22681 cctaagtttg ctaaagatgt caataacgaa cttcctccat aacttacaaa aggtaatgtt
    22741 actccagtta ctggtattaa cgcaaccgtc atacctatat tttggattat ctggtaacca
    22801 aacattccca taacaccaac cactatgagg gttccataaa aatcttttgc atctcttgca
    22861 attgctaaaa gccttaatag gaatatcata aataagatta tcaacactgc cattcctatt
    22921 acaccaagtt cttcacctac aacagcaaat ataaaatcac tatcttgtac aggtaaaaaa
    22981 tcttcttgat tttgacttcc attgtaaagt cctttaccag ttacgcctcc agaaccaatt
    23041 gcaatcagag attgcataac ttgatagttt ccttttagag ttacatcttc tggatttaga
    23101 aaagcttcta ttcttacctt ttgatggtct gccatcatta aatacatcag tggcattgac
    23161 actaatagta tgattattcc tctttttatc aactttgaac taagacctgc tgtgaacagc
    23221 attgcaaata tcatacaaca aaatacaatt cctgttccca agtctggttg tgcaatcaat
    23281 aatccgataa atggaagaga ataaactaca acaggcataa cttcctttaa cgtatttaat
    23341 ttatcctttt tggattcaag tatctttgca taacttagta caaatgttaa tttgactatt
    23401 tcagatgtct gcaagtcaag tggtcctaag ttaatccacg acctagctcc accttttact
    23461 gtcccaattc caggtaataa aactatggct aacaaaataa gacttattat ataaagcgct
    23521 ttataatacc tgcctagaag gttatagtca aaaaataata tgactataat cattcctata
    23581 ccaagtacaa aagctaatcc ttgtttaatc aattgattat atgaacctgt tgaattagca
    23641 tgtgttgcac tactaagtat aacaagccca aaaataaaga tagctaatac tgtaactata
    23701 agtttccagt ctaactgttt tatcaactta attgtcgact tataattaat attgattttt
    23761 ttcaaagaat caccgtcttt ctatctttaa acatataatt aaataaaagg ggcatatacc
    23821 aataaggata tccccctttt aagcactaat tacatacatc tatcttttat attctttagt
    23881 ggtatattag caactaatgc agatacaggt ttgtcatcat gctcacctct gcatttagac
    23941 atttttattt caagaccatc atcttctatt tctgcataat tagctattac tttcaaaatg
    24001 tctgttttta tcatctctaa aagttgtggt gaacaatcta ctctatcatg aactaaaact
    24061 agctttaacc tctctttagc aacagattta ctagttttag cctcgttaga aaaaactcta
    24121 aataaatcta acacagatgt atcctccttt gctacttagc catgctaaac atttttttaa
    24181 gtctaccaaa gaatccatct tcaacttcaa gatcaagtag aggaacttct tcatttagta
    24241 tcctttttgc gatatttttg tatgcttgac cagcaagtga cttagaatca agtatagctg
    24301 gctctccttt atttgttgat ataattatgc tttcatcatc aggaacaaga cctaacaaat
    24361 ctattgctaa tatttctatt atatcttgtt tatccatcat gtctccacgc ttaaccatat
    24421 catttctaat tctatttata actaatctta tctcttttat ttcatttgct tctaatagac
    24481 ctattattct atcagcatct cttactgctg atatttctgg attagtaact acaatagctc
    24541 tatctgcccc agctactgca tttttaaagc cttgctcaat acctgctgga caatctatta
    24601 ttatatactc gaaagattct tttagtttct cacacaggtc aatcatctgc tcaactgaga
    24661 cagcattttt atctctagtt tgtgctgctg gtaataaata tagattatca aatcttttgt
    24721 cttttattag agcttgctta agcctacaag ttccttcaac tacatctact atgtcataaa
    24781 ctattcgatt ttcaagaccc attactacat ctaagtttct aagtccaata tctgcatcca
    24841 caactactgt ttttttattt tctaggctta gcgcagttcc taagtttgct gcggtagtag
    24901 tttttccaac cccaccttta ccagatgtta taactataac ttcgctcata atactacccc
    24961 ctatttttct ttctatttgt ctaactttga caaatagctt tcgattacaa ttcttccatt
    25021 acttacaaag gctatttctg ggctaatttc tgattcactt tcataatttt cttcatcatc
    25081 tggagcttct gcaatattat ctgctatttg taatatttta ggattaagat ttccagcaac
    25141 aacatatgca aattcattgc cttctgcacc tgcatgtaca aaaccttcta ttttacccat
    25201 tacaaaaaca ttacctcctg ctacaacctt agcaccagca tttatatctc ccataacaac
    25261 tgtatttgat tttgaaagga cttttgaacc aggtttcata tcattcaata taactacatc
    25321 accttcaaat tcaatatttt caccagatct tagggtattg acatattttg ttggaaaatt
    25381 actattttct tcaatttttt gatcttcaac aaattccaca tcaaatctag aagtaattcc
    25441 ttctttaagt tctagaatct ccatgtcagt taaacaatca ctattaattt tactaatttt
    25501 agccccatta aaaaagccaa catatgcttc caatttgttt attatttttt cctgtatttc
    25561 ctcaaatgga gcttctcttt ttatatttac tattatccct cttttattac ccttgaactc
    25621 tactagttct tgactacaaa tttctcttaa agacataaca acctccagag tgatatatca
    25681 tttatattct tcaaatacgc tttaaaccct tttatttttt ctatataaag ctaaagttta
    25741 tacatagatt gagctatcta ttaatttgtg actcgaaatt tatattttcg tcagaagaat
    25801 tgttaacatc attcgtcttg ttgtcatttt tactattagt tggctctaat cccatataag
    25861 ttccaataac ttctctagtt ggtaaaagtg agaatacact tgaatcacct tgaggaatta
    25921 cacatacaac agctatttct gggtcatctg ctggagcaaa agcaacagtc cacgtaaaag
    25981 aaccataatc ttgtttaaat ctatctattt ggtcatctgt tatttttgga tttaattctt
    26041 ttatagcttt tcttagatat gaagaattca ccttatcagt gtcctctaat ctaactttta
    26101 ctccatcttc taattcttcc tctaatttct ttctttcttc gtctttcaaa tctttatttt
    26161 ctaatttctt ttttatttcc ttttccttag ctaatgaaag ctctttttct ttttctgctt
    26221 tcatcttatc agctagttta atcgcatcat ttaggttgac attataagat gacatatgac
    26281 tttttaaata ttcatactcg ttatctgtag gtattttccc acttttctca gctgtaccag
    26341 tttttgctgc tacatctatt ggaaaatcag caaaagcact cttcgctgta ccttgtcttg
    26401 caaccaattt catacctttt gttaattctt ttaagttatc tggattttta aaaggtattt
    26461 tttcgacttt cttctggtca ttaattttaa ctgatgaata atcacttgaa acagctctat
    26521 caactacaga taattctact aaattacctc catttgctat agcagctaca tatcttgata
    26581 tttgagctgg tgtataagca ttttcacctt gacctatagc taagttaaat gtatctgcag
    26641 tactccattt tgcaaagtta aaataactaa atactgctaa atctgctact tcttcaattc
    26701 tatcttcttt aacatccaat ttttttagcc tattcattgt ttcaactcta ccaggagttt
    26761 tcttttctgc tgcccagctt acaatctcat tgattctttt ctcatattct ttaggatttt
    26821 tttctctagt tatatcaaca aaatcatttg ccatttctct ttctaaattt gactttagaa
    26881 gagcttgtgt tgatttcaat ttatcttctg tgctaggaac tttacctgct ctttcttcta
    26941 cttcatcttg aagccctgta ttttggtcaa gcccaaataa ttttgcatac tcaagtattt
    27001 tatttgcatt catatctata ccaatgcttt ttccatctgg ccatgtttta cctgtaccaa
    27061 ttgttgccat atatatatta caagactctt gtattgcttt atataagttt gtcataccat
    27121 ggtttcctct accatggttc catacatagt caccaaaaga ttttttacct aacattataa
    27181 ccccagggtc atttatagta aagtttggat ccagaccatt ttctaacgct gccattgaag
    27241 ttaccatctt aaatgaagaa cctggctgaa attccccttg tgtaaccaag tttaaaagtg
    27301 gacttcctgc tagtaagtca tttggatttt ttggttgaag tgctttataa tcctctgtag
    27361 aaataccttt tgcaaattta tttgggtcat aattaggata acttgatgaa gctaatactt
    27421 ctccattttt aacatcaata gctataagag ctgctgactg tgcttttcct gcatatgcac
    27481 taattggttt gtccccaaat ttacttttaa aagtacctcc tttagaagca acttcgatta
    27541 tctgttttaa tgcattgtct gaaacttctt gtaaatcttt atctagtgta agatacacag
    27601 tatctcctga tttaggtttt ttagattcaa tttctttact gattctaccc aatgcatcaa
    27661 ctttaaccat tttataacca tcagttcctc ttaatctact ttcattactc ttttctactc
    27721 ctgcaagacc taccatatct ccagtttcat aacctttttg aaggtatgat tctatttgag
    27781 tggatggcat ttttcctaca tatcctaaca tatgagaagc taatgaccca ttaggataat
    27841 atcttactgg ttctactgct attgaaacac caacaaggtc catagcactt tcttcaattt
    27901 gagcaatcgt agtttctcct acatccttag caatagttac tggattatat tgagaatatc
    27961 cttttgattt tatcaaatcc cttacgacca ttatttttct tgcatcttca tcactcaaac
    28021 ttttatcaat ttctaatgca tcactatttc ttactttttc aaacgcttct ttggcactca
    28081 gtttagtttc ttttatctta taactagcca accaatctct cttatctctt tctgctgtga
    28141 acatccattt actaactaaa ataggtggat aatatccatt ttcatttagt tttgcctgta
    28201 atcttgtcgc atccaatctt ttatcttctt gagataatat tccagctgat ataagtttgt
    28261 ccaccaagta ataaaaactt tccttagcat tataatcatt tggaatacca ttttctgatt
    28321 tatattccct aatatctctg tcatatgtat aatagtactt tccattttct acatatatag
    28381 gaaactcatc tacatattct tcaccatttc tctccagcaa atttataagt tttaatgata
    28441 tttcatttgc tcttgaatgc ttatttgcat ctttcttatt aatatcgtta cctgaaactt
    28501 gaacagtaaa taagttttta tttcctgcca acagtcttcc atatctatct tttatttctc
    28561 ctcttggagc ttctattgcc aactttttat atgttttatt ctcagctaac tcattgtaat
    28621 attcatattt aaatgtagtc atatagatta tttttactaa aatagctaaa aatatcacgc
    28681 ccatgactat cttaattatt tttagtctat caacttgttt attttcttcc atgaaatcac
    28741 caactaatct tctttaagtt ttaaaactgc tcttttagat aagcgatata ttactaaacc
    28801 aattaaacta ttcactattg gtgctactag tagacctttt acaaaaagtg ttgatatgtt
    28861 gtagctttga taaattatac tagatgtacc tatattgaca attgaatcaa ttaaactgcc
    28921 tataaaaatt aaaacgaaag taataatata actaccttta tatagctgat ctctcatgta
    28981 tccaattgca tatgcaataa taaacaaaat taatgcattt acaccaaaaa ttccaccaac
    29041 ggttatgtct ttaataagcc ctattattgc tgctataatc ccaccttcta attcatctaa
    29101 ataaagagag attatggtta catatataag aactaaatta aagcttatgc caaaaatatc
    29161 tatataattt gttatactat tttctatagt cataagcaca atccccaaca gacaaagtaa
    29221 aacttttttc attgttttta tcccctttat cctatatttc ttggttctat gactacaacg
    29281 tcatttatat tcttaaaatc aacataaggt tttacaacta catattttaa tgacttatct
    29341 ttatcatcaa ccactttttc aacttcgcca attggtatac catctgggaa gaatccaaga
    29401 cctgatgttg ttattatatc tccttgaatt acattatatg atgagtcaaa catatatcct
    29461 tgcaaatatc ctttactatt ataactatct ttattatcta aagtagtatt ttgagtaatt
    29521 gtacctttag cattggcatc ctttgctagt ttaaagctta cagatgcctt agaatccaat
    29581 agtgaaattg ccttactata attgttggaa acttcataaa ctatgccaac taatccacta
    29641 ccattcataa ctatactttc tttttttaca cctgaatttt ttcctgcacc tatgacaaaa
    29701 ctctcatacc agtttccatc atttttacca acaacacttg ctgaaatact tgtcgcctta
    29761 tactcttctt gtacaaagtt cagtgtcttt tttaactctt ctagcgattc tgttttatct
    29821 agtttggcat ttaaagctat catatttttt ttaagttttt cattttcttc ttctaatttt
    29881 tttacctttt tagaattatc tttaaaattt gctacatctt taaaaccatt tttgataaaa
    29941 gaaaatccat catttattcc cttacctaca cttgtaatag catctgaagc tactcctaaa
    30001 tttactggac taccactaga aaatttacca attgatatac ccacaattcc aattaaagtg
    30061 atagcaacta cgcccgttgc tatcacttta acattaatcc tttttttctc atttttgttc
    30121 ttgtcaaatc tcaaggccat caccaacttc taattcttag tattcatcat taatactttt
    30181 tcaaagattt cttggtcttc aacagattta cctgttccaa gtgcaacaca atcaagaggt
    30241 gtttctgcta tttgtacaga cataccagtt tcctgtgtaa taagcttatc aagacctcta
    30301 agcaaagcgc ctcctcctgt tagcattatt ccgttttcca ttatatctga ggctaattct
    30361 ggtggagttc tttctagtgt agattttatt gcatctacta ttgaacttac aggttctttt
    30421 aatgcttctc taacttctgt agagcatatt tctattgttt taggtaatcc tgagattaaa
    30481 tctctacctc ttatttgcat atttatttct tcatcatctt taaatgtaga acctatgtta
    30541 atttttacat tttcagcagt tctttcacct atcataagat tatattcttt ttttacataa
    30601 gccactatag actcgtcaaa ttcgtctcca cctattctta tagatttagc agtaacgatt
    30661 cctcctaaag atattacagc tatttctgaa gtacctccac caatatcaac taccatatta
    30721 ccttctggtt cttcaacttt taatccagcc cctatagccg ctgccattgg ctcttctata
    30781 aggaatgcat ctttagctcc tgcttgtctt gcagcctctt ctatagctct cttttctact
    30841 tctgtaactc caaaaggaac acatatagct attcttggac ttacaacacc ttttttatca
    30901 gccgcttttt gtataaaata gctaatcatt gattgagtta tgtcaaaatc agctattact
    30961 ccatctttca taggtcttat agctactata tttcctggtg ttctacctat catttttttg
    31021 gcttcttcac ctactgctaa tacctcttta ctatcatctc ttattgcgac aactgatggt
    31081 tctctaacaa caataccttg tccttttatg taaactaatg tatttgcagt ccctaaatct
    31141 attcccatat cctttgtcat cttattaaaa ctaaaaaaac cttttttttc tttctttttt
    31201 tccttagcca tgattttact ccttcctact attaagaatc atgtttaaaa cattcttcta
    31261 ttattttatc acatataaag tcaaattatc atattttctt taaagctaaa gtataatcca
    31321 tctccaataa ttatatggtc tattatttct attccaatta tttctccaca tttaataagt
    31381 cttgatgtga tatttttatc ttctcttgat ggttctacac ttcctgaagg gtgattatgc
    31441 atcactatta tcttacttgc acttcttctt atagcttctt taaaaacctc tcttggatgg
    31501 actaatgacg agcttaaagt ccctatagat acatctacat cagatattat ctcatttttt
    31561 gtgtttaaaa gaaccgcttt aaaaacctct ttttttaaat accttaggct atccatataa
    31621 tacctctgta tatcccaagg attccttatt ttatacttta taggtttaaa actagctact
    31681 ctagagccta gttctaaagc tgctttaatt tgggttgatt ttgataaccc aattccatct
    31741 atattacaca gctcctctat tgtcatatct tctaaatgtc taataccctg aatatctcta
    31801 tttattatat agttggctaa ttcaatagca tttttattct tgttgccagt tcttaaaagt
    31861 atagccaaca actcagcatt tgataagctt tttacgcctt tggcaagcat cttttctctg
    31921 ggtctttcct ctggtgccat ttcttttacc ttaatggttg aattaaatga ctttttcaga
    31981 taaatcacac tccataaaaa agatttatac taaaatattt ttttaatagg tcgcctaacc
    32041 ttgaaattgg aagaccaact atattaaaat aatctcctct aatttcttca actaacaaag
    32101 ctccataacc ttgtatacca taggctcctg ctttgtcaaa tgactcatta gttttcagat
    32161 aatcctcaat atcctgctct gataacgttt taaatttcac attgctgatt acatagtcaa
    32221 ttaccttttt atcttcgcac aagtttatta agctaatacc tgttatgact tgatgctctc
    32281 ttccagatag tctttttaac atatctcttg cacaagactc atcttttggt tttcctaaaa
    32341 tagcattgtc taaaacaaca actgtatcag ctccaataac aacatcttca ttatgttcag
    32401 atgctacaga catacttttt tcaaaagcta atctcataac taaatgtttt ggtgtttcac
    32461 cttccaatat aatctcatca atttcatttt taattatatc aaatcttaca ttcgtattct
    32521 ctagaatttc tttccttctt ggagaggctg atgccaagat tatattcatt tattcacctc
    32581 atttgtacgt aatttgtacc tatttagtct atcactatat tgtaaaaaat tcaacagaaa
    32641 tgtcgaacct tttttgttac actattgtta tatttattac cattagaata aatatacata
    32701 aaatagaggt atggaaatta ttccatacct ctgttttatg tactcattag agatatggaa
    32761 attattccat atccttattt tgtccatatt acaaaatttt aatagctttc tttggacatt
    32821 tttccataca taaatggcat cctacacatt tatctgcatc taccttatgt ttttctttta
    32881 attctccctc tattgcatca aacttacatt gttttttgca cactgtacat ccaacacaaa
    32941 gttcttggtc aatagtaact ttctttttct tagttatgtc acctgatatt acttttgtag
    33001 ggcattttgc tacacattgc atacaaccta cacacttatt agggtctatc ttagctattt
    33061 tgtcttcaaa tattattgca tcaaatttac aagcttttac acacattcca cagccaatac
    33121 atccagcagt acatttttct ttaacagctt taccaaactc tttgctatta cactctacaa
    33181 ctacttcttg actttctggt tttgtgatta ttataccctt aggacaaact tctttacatt
    33241 ttccacaatt tacacacttt tcttcatcta ttactgctat tccatcaact atagaaatag
    33301 catcaaattt acaagcatct ttacatgttc caagacctaa acatccaaat ttacacatct
    33361 tagcacctga gtttaaaaca tttgctgctc tacaatctga tattccttca tactcatatt
    33421 tatcttttgc acttgaacaa gttcctttac aaataacttt tgctacttgt ttctcacctg
    33481 cttcagcact tattcccatt atttctccaa cttttgcacc aacatctgct ccacctacag
    33541 ggcaaccatt aactggtgca ttgccttcaa ctatcgcatt tgcaagacct ccacaacctg
    33601 gaaatccaca acctccacag ttggctcctg gaagtactcc tagtatagct tccactctct
    33661 cgtctacttc tacagcaaac tttttagatg caaaatctag tactatcccg aagattaagc
    33721 ccataattcc taaaactaat acagctgtaa gtatcaccat tttcacccct cttttttata
    33781 gctttataag tcctgtaaat cctaagaaag ctattgacat taaacctgct gatataagcg
    33841 ttatagggaa acctttaaat gcttctggta tatcagctaa ttctagtctt tctcttatac
    33901 ctgcgaatat tactattgct aaagtaaatc cagctccggc tccaaatccg tttattattg
    33961 tttctactaa attataactt ttttgaacat taactagagc tataccaaga actgcacagt
    34021 ttgtagttat aagaggtaaa taaactccta atgcttgata taaagatgga ctcatctttt
    34081 gaattaccat ttcaacgaac tgaactatag aagctataac caatataaaa gctattgttt
    34141 gtaagaatcc agttccagtt tttactaata aaatctgtat aaaataagtt ataattgaag
    34201 ctagagttaa aacgaacgta actgcaactc ccatccctac tgctgtatca accttcttag
    34261 aaactcccaa gaaaggacat atacccaaga attgagatgt tataacgtta ttaacaagaa
    34321 cgatacttaa aaataaaagt attaaattca tttattacac ctccactatg cttttttact
    34381 tcttaattta ttaaatcctg caaataagaa tcctaatgtt aagaatgcac ctggtggtaa
    34441 tataaatatt aatactggtt ggaaagatgc tccaaataat gtcattccaa ataaactacc
    34501 atttccaagt aattctctta ctgcacctat tattgtaagt gcaacagtaa atccaagacc
    34561 ttgacctaca ccatcaacta ttgaaggcat agctcctgtt ttgaaagcaa aactttctgc
    34621 acgagctaat attaaacagt taacaactat taatggtata tatataccaa gagccttatc
    34681 aagagcagga acatatgctt ttaaaagcat acctactatt gtaacaaatg tagctataac
    34741 tactataaat ataggtattc ttatcttatc tggtgtaatt tttcttatta aagatataac
    34801 taaatttgca catattaaaa ctgctgctgt tgaaagaccc ataccaattc catttattgc
    34861 tgaagttgta acggctagtg ttggacacat acctataact tgaacaaatg ttgggttctc
    34921 atctattagc ccatttttaa atactttagc taaattcata attaaccctc cttatttatt
    34981 aagagcacta ttgaaaacat ctatagcagc atttactcct gtagtaactg ctgtagatgt
    35041 aatagttgca cctgatattg ctaatatttg attatctgct gttgtacttc cttttgctac
    35101 ttcaagaggc tcagcagttt ttcctttgta ttgaccctta aatgcatcat ccttagcttt
    35161 tgctccaaga cctgctgttt ctgacatatt accaatgtca acacctgtaa cttgaccttc
    35221 agatgatata cctaccataa cttcaatttc tccaccatat ccacttggtt tagcttttaa
    35281 agtatatcca accacttcag aaccatctaa accttcatac acttcagcta taagaccatc
    35341 tccaaggcct ttgtaagtat cttccttcat ttctttaaat tcttttgctt ctggaaggac
    35401 tgcttttcta agttcattat ttgcttgtat atttctttgt tctattactg gagctgtaac
    35461 ctgattagta gctccaagag ctaatgcagc tattgcactt atagcaagta aagtaccacc
    35521 taatctcacc atactgttca ttatttagcc acctccccaa atactctatt tctaacaaac
    35581 ttatctataa gtggagcaag acagttcact aatagtattg agtaagatac accttctgga
    35641 tatccaccat acattcttat aacagttgtt ataagaccag ctaatacagc gtatattatt
    35701 tgaccttttt tagtcatagg cgaagttgta taatccgtaa gcatgaagaa tccacctaac
    35761 ataagtcctc cagcaaacag ttgatatatt gcgaaagtta tattaaatcc acctaaaagg
    35821 aatgttaata taaatacagt tgctatgtaa aatactggta taacataatt tattatgcct
    35881 ttatacatta ggtatactcc acctaataat aataatattg ctgatgtctc acctatacat
    35941 ccaccaatat tccctatcat catgtcagca agactaattc cattgctaga aaggtctgcc
    36001 agtcctgctg ctccattttt caaaaagctt aatggagttg ctgtagtaac tgcatctaaa
    36061 tttttaccta tccagttaac acctggttga gtccaagcag tcattgctac tgggaatgat
    36121 gctaataaaa atgctcttgc agcaagtgct ggattgacaa agttacatcc aattccacca
    36181 aataccattt taactactaa tattgcaaat attcctccta ctagacacat ccaccaagga
    36241 agtgatgctg gtacgttaaa tgctaataat aatcctgtta caacagctga aaaatctcct
    36301 atagtacttt tttgcttcgt aaatttttga tataaaaatt cagtacctac tgtaccaagt
    36361 atacaaaaaa acatagcact caaagcatta agtctaaaga agtatactcc tgctactgct
    36421 gctggaagga gtgctataat aacttgtttc attatatatg aagtatcttc attacttctc
    36481 acatgaggag aagatgatac tatcaactta ttttccatcg tttttccccc ttaactttct
    36541 ttatttctga gcagcttgct ttcttctctt tgctcctatt tctctctttg ctgatcttat
    36601 agattgaagt aatggtcttc ttgctggaca aataaatgag caagacccac attctataca
    36661 atccattgct ctatgatatt cagctgtgtc atagtcatct tttaaagaat atgcacttat
    36721 gaaaagtggt tgtaagaatg atggacatac atctgtacat cttccacatc ttaaacagtt
    36781 ttgaatatct ggagtacgtg attcttcctc atccaaacat aaaattcctg aagaaccttt
    36841 gttagtcgct atttcagtag tatattgagc tattcccatc ataggtccac ccattataac
    36901 cttaccaatc ttcttatctt ctttaaatcc accacattgt tctattattt ctgaaactaa
    36961 tgttccaact tttgttatta ggttctttgg ctctttgatg caactacctg ttattgtagt
    37021 gattctttca accaaaggca tacctgtttt aatagactta gctatctgtg ctgctgtggc
    37081 aacgttgtca acaactgcac ctgctgctat tggtaatcca ccagatggaa cttctttgcc
    37141 tgtacacgca taaataagtt gtttctctgc tccttgtgga tatttcactt gaaggccaac
    37201 aacttcgatt tcgctatagt ctttagctac attttgaatt gcttctatag catctggttt
    37261 attcgtttca attcctataa atcctttttt gacatctaat accttcatta atgctcttaa
    37321 accaaacaca acatcttctg gattttcaac cattaatctg tggtctgcag ttaagtatgg
    37381 ttcacattct gcaccattta atataactac ttctgccttg ctatctggtg gaggagatac
    37441 ttttacatgg ttagggaatg tagctccacc catacctact attcctgcct cttttatgat
    37501 acctactata tcttctttgc tcaaatcctc taactgacct tttggttgaa cactctcatg
    37561 taattcttcc ttaaagtcat tttcgataac tacacattga gctgaacctc ctggtacttc
    37621 atgttgttca atagcaataa ctttacctga tactgaagaa tgaacgttac atgaaacaaa
    37681 accttgttgt tcacctattt tttgcccaaa ctttacttca tcaccaactt caacaatagg
    37741 tttagctggt gcccctatat gttgctgaag aggaatgtaa actatctttg gagcttgagc
    37801 tttttcaagt gcctttgtgt tagagtactc ttttctatat ggaggatgta tccctccctt
    37861 aaaagttaag agtttcattg ttttaccccc ttatctataa aaaaacattt tttctgcctt
    37921 ctataagtat actatatata ttaaaaaatc ttaacaattg ttaaaaaaat atccgtattt
    37981 ttataattta ttttataaat caacacctct atattaagtc aaattgagga aaaggattgc
    38041 ttaattaaac aatccttttc atatagcttt ctaaagtcca aattttctgt attttatttt
    38101 atagaattta taaacataga gtactcctgc atggatgata aaagcagact tttacttaca
    38161 ctatattttt cttcatttgc tgcttttgaa gctgtatcaa ttttttcatt cacattcttt
    38221 acatactcta ttaaattatc tttaaataaa cgcatttcag aataatcaat cttttcagct
    38281 tcttttgata tattttgtga tattgccttt ctatttgtca aaatagtatt atatttttcc
    38341 atatctacat tattttcagc attcgaccaa aaacttgatt cttctttaaa gtttgttatt
    38401 aatttattta attctttaga tatactctct atataagcgt agttacttgt atactctaaa
    38461 gacaacatag gtgcatctaa gtgtgataaa aatgcatctg gaaacacctt tcttacactg
    38521 cttatctgct ttctaacatc attttcatca aaagaggaat aggtctgtat tttttttact
    38581 ccatccttct ccataactga aaaaggtatg tcattattaa ctaatgatgt ctgtattttt
    38641 ttcaaatcat cattattatc tattgcagca acttgaatag tatacatatc ccagccttct
    38701 atagtagcta atttgacttc ttctggctct ttagtgttat ttaccgcttt ttctggatta
    38761 gtttcttgtt tatcatctga attggtttgt gatttagatt ttttcccttt ttttattgaa
    38821 tttaattcat cagatatatc tttataagtt atatctgatg aattatttag aaatggtatt
    38881 ttagccgata catactccaa tatcttgcta tcttttattt ttgtataaga ataatagcca
    38941 attagacaca agcaagcaat cgttataaca tatttacgta aatcaatctt atgtctatta
    39001 ttattaaatc ctctgtatat cgtttttctt ctattcatta gtttgtccct cccaaaatta
    39061 tattattaat aaagtatatt tttaagagtc acaatttatg aatataaata attatttctt
    39121 ctaatttttt aataagaaat tgtacttact aaacaaatct tcttgcacca agtaatactt
    39181 tagaccaata tgaactagtt aaattatcca ctttaacctt attaggatta gtctgagtac
    39241 cactacaatg gataaattta ctatttccta cgtatatacc tacatgatta gttgttccat
    39301 caccatcagt gtcaaaataa actaaatctc ctggtgcata atttcccata gaaattgcac
    39361 ttccaaaatt agcctgttct ctagaaactc taggaataga aacgcctaca gaatgtttaa
    39421 aaacatactg tgtaaatcca gaacagtcaa atttatcagg tcctgaagct ccccattgat
    39481 atggtattcc aataagagta tatgcaaaat ctacgattgt tgaacctttt gctgtagatt
    39541 tatctgaatt tccagtaaat gatggctttg agttactatt agattgagaa ttttggttag
    39601 atgatgaatt tggtttttct tttgtatcct cattagtctc agaaatataa ctggcactca
    39661 cccatccaat tgttccactc gataacttta ccttatacca accattactt ttagctttta
    39721 attcaacaac atctccacca tttaattttc ctattataga atagcttgtc ccaggaccac
    39781 ttcttacatt taaactcaca gcagatgtta ccttaccatt cttgccttca attgattctt
    39841 cgctagatgg ttttttatca gaattattag tactatttga attactagaa ttgttcgttc
    39901 caacatcttc tgatgtttta gaaatatatt ggctactagc ccatccagta actccatttg
    39961 atagttttat tttataccat ccattgcttt gttctagtaa ctttactaca tctccattat
    40021 ttgctttacc aactaatgaa tagttagtac ctgcaccact tcttacattc agtctagaac
    40081 tcacatttac tttaccattt ccactaatag ttgtcccact tgaagttgga ttattttgac
    40141 ttgatgtacc ttcagacgaa ccacttgttg atatgtattt tgcacttccc catccaacaa
    40201 cagaactcga tacccttact ttataccatc cattagactt ttctaaaatc tctacagttt
    40261 ttcccttgta taattttgct accttatcgc aatcagaact tggtccactt cttatattca
    40321 aggcacttgc tgttactgtt cccttttcaa gagcacttgc atttatggag ctaacagata
    40381 ctgctactgc cccaattcct aaagctgcta tagctttttt cactactatc actcccccca
    40441 acaaattttt atagtcataa attcataaca ttattatcca tttttagtcc ctacaattta
    40501 atgataactt attttcttat taattgtaaa gaaattataa acatatcctt aaaattagtg
    40561 atttttagga agtatttcaa tccaataatt atctgggtcc gctataaaat aaattcccat
    40621 actttcattt tcaaaacata tgcaatctaa atctttatga agtttttttg cctcatcaaa
    40681 ctcctcaact tctaaagcca gatgaaattc attgtctcct aaattatatg gtctatccca
    40741 atctctaagc caagttaatt ctaatgtatg actagtaatg ccatctccta aataaactaa
    40801 tataaaactt ccatcttctg cttccttgcg ctttacctct ttaagcccta aagctttttt
    40861 ataaaaatct aaactttttt ctaaattagt aacattgaaa ttgttatgac aaaaattaaa
    40921 cttcattttg aaatcactct ccaattttta ttttttttat attatatcat tattataaat
    40981 ttatttaaat catattaagt taaaaatttg aatgatgatg accaattacc aaatcatggt
    41041 aaattattta aaagaatatg tcaaaaaaag aataagctct ttcaaatgca taaaaaattt
    41101 atacccaagt tatacttaat catgcaaatt ggcagaactt attctttaaa actctaactt
    41161 ttaagttttt ctttaataat ataatttatt actttttttc taatatcttc agcattataa
    41221 tcatcttcta cttctatatc caaaagtttt gctattgacc tcatatcttc tctagtcttt
    41281 gacctatagc ttgatattaa ttcatctttt attttctctg gttctaaaag atattcttca
    41341 tctcctcttt tgaaaacaac gtatttttga gcatatgaac ttctattgta gtatatatat
    41401 cttgatattt ttcttaaaat ttgattatat gaaagtcgct tgttaatatc aagttttaag
    41461 tactctgaaa aagcaaatag ctcttttttt gatttaaata atgcttcttt ctttatagtt
    41521 cttgatattg aagttacact ttcttgatat gcacactttt ttaacatttt taaatatact
    41581 ctattaagac caatactttg attgaatttt tttatattat tattaataat cttatccaag
    41641 ttaccttcaa agtatttttt tgctcctttt tgtgatacat aactctcaag ttctttgtgg
    41701 gccatatcaa gtatcatttt ttttaaatcc tctttatatc ccctagattc catgatactc
    41761 cctcccttag ctatttatag tatattcaaa aagctcaaga aatgtgagtc attacaaaat
    41821 ttttttactt tttatgtata tattaattta aaaggggaga taatagtaat gtaaaatcaa
    41881 acatactcaa tctcccccat ttttagacct ctattactcc cccaatagag gtcttttttt
    41941 agtttatcaa tttctattca attcccttta gttcaaatcc taattctgct atcacttctt
    42001 ttaatttttc aatagataca tcatctttca tatctacaga tgcacactta ttttctaaat
    42061 ctacatctaa aacttcaata ccatctatat cttctgttaa tgcagtttta agatggttta
    42121 cacaatgacc acaactcata ccttctacta atagtttctt cttcatttaa ttacctcctt
    42181 ataccctata agggtattct atcatatagt ttatactttt taaatagaaa ttaatcattt
    42241 aatttgattc attcgatttt atatctaaat tagatattcc ctcatataca tcaaaatcat
    42301 ttggagtaat tttacctttt aatctactat tacttacaat atagttgttt ctcacagcta
    42361 aacttataaa tgttgcatta tcttttatat atgtctgtac atctttgtat gctttttttg
    42421 tttcaatttc agacgtagaa cttgtaagtg cagacatata tccatttaac ttatcatcag
    42481 tatatccact actcgctata atactacttg catctggtat aattgatagt ttccatccaa
    42541 ctaatgctaa atcataattt ttagaattaa gagcattttc catatcctta tctgagagct
    42601 gatttactgt actatttatt cctatagctt ttaagttttc atttattatg tttgcagttt
    42661 ttattctctc actattatct ctgtttacta ttatctttaa gttcatttca gaaagacttt
    42721 tctttacttc ctctttttct ctattttttt tctcttcagc ttcttttttg attctatctt
    42781 cttctgcttt tttaactttt gcttcttctt ctggcgtaag cttctttgag ttctttttag
    42841 ctgatttttt ctgatttttt actttattgt cattttgatt tactgagttt acatttgcat
    42901 attctacctt agcaagacac tctatcgcct tatctttatt aaactctaaa tccttcattt
    42961 cactattata gtattttgat tttgaattaa gtggaaaatt aactggagta gcatcatcca
    43021 tataaccttc actaataatt ctatctttat ctatagagtg tgcaattgct tttctaaaat
    43081 taacatcttt gaaaaaagga ttattataat taaataatac acactcataa tctcttcctt
    43141 gatattttgt tatattaaac tctttttctt gaaacttact taaatcattt aatgtaacat
    43201 tggttatatc actatcaaga gccataacca tagatgtcct tgcatcttca ttaggcacca
    43261 tacctacttt tatgttcttc atggtttttg gaacttcttc atagtaatct ttgtttacag
    43321 ataaaaccat tccttctctt tctgtatatg attctatttt atatttccca tttcctatca
    43381 tattattatt cttgtcattt acatcttttg aatctaaatg attttgagat acaattggaa
    43441 aaattaaact atcaattgaa aaagcatatc tagctttaaa ttttattgta aaatctttat
    43501 ctgatttaat attcacagaa gctatatttt tagtaaattc attatatgga ctatctgcac
    43561 ttttttgaat taaaccaata gtatagttta catcatttga agtaacattt tttccatcat
    43621 gccactttgc atcttttagc tttatatcta tactcattcc atcctgagct atattatact
    43681 ccttaactaa ttgaggaatt acattgtagt tctcatctat agtaaataaa ctatcataaa
    43741 ctaaattcat tatataacca acagacttat cagtattagt tataggattt atagtttttg
    43801 gagttaccat tgttaagttt atatacttag catctataga actttgactt tgtaaacttg
    43861 aatcactact actttgtttt gttttagtat tactacaacc agctaccata agagttatag
    43921 ctaaaacgac tgttaagact tttattctct tcattagttt tttcctttct tgccatatat
    43981 cttattataa tgttcgtaat tattttttac tttttctaca tattttgaag tttgcttaaa
    44041 aggtatatca tgtagatttt cgccatcttt actatattca ttattttcta accatttttt
    44101 cacattacct gaaccaccat tatatgcagc tatcactaaa tctaatttac caaattcttt
    44161 gtataactta cttaaatacc aacagccaag tcttatatta gtctctgggt cgaaaatatc
    44221 cacatttttt aaatttagtt cctctgctcc ccaatctcta gttatgtcta atatttgcat
    44281 taatcctttt gcttcctttt ttgaaacagc agaactatta aacttacttt cggctttaat
    44341 aacactgtaa actatatttt catctaaatt aaattctttc gaatactttt ctacatactc
    44401 tgaatatttt ttaggatata aaaatttatg tattactttg ctttccatta atagtgcccc
    44461 aaataagatt ataaaaatag atagaatcaa tactttctta ctattcacgc caattctcct
    44521 tcatgtactc aataaattta tgtgctttac tttctaattc agttattgtt cccgaattat
    44581 ctattatata atcaccatat ttggattttt cttcctgact catctgtgaa tttatcctac
    44641 taagtgcttc ctgctcactg caattatctc tcttttgtat tctactaatt tgtacttctt
    44701 gtttacaagt aactactaat agcttgtcaa ccatatctaa aaaaccactt tctaccaata
    44761 ttgccgcatc taacactact atattttcgc ctttttttct caatttttct atttcactta
    44821 ttattttttc tcttattcgt ggatgagtca agttatttaa ttccttaagt ttttcttcat
    44881 cactaaaaac tattttccca agagcttttc tatttagagt tccatcatca ttttttatac
    44941 tttgcccaaa atggacaaat actttttcca ataacaactt atcctcaaat atcttcctgg
    45001 atataatatc agcatccact ataggaatgt taagatttct aaatatattt gataggctgc
    45061 tttttccaca gcctattcct cctgtaagtc ctaatatcaa cataaaatca cctactttgt
    45121 ctcataccaa gaactaccta catttaaatc tacatctaag tgaacatcca tatttacagc
    45181 attttccatt tcttctttta ctattttctt aactatatct atttcatcat caattgcttc
    45241 aactatcaac tcgtcgtgaa cttgtagtat aagttttgat ttcaaattgt tctcttccaa
    45301 ttttttatga acatttatca tagcaatttt tattatatct gctgcacttc cttgtattgg
    45361 tgcattcatt gcaaatctct ttcctctatt tctttccata aaattgcttg actttatttc
    45421 tggtatatat cttcttctgt ttaaaattgt tacagcatat ccatcctcac tagccttttc
    45481 tactgttgtg tccataaact cttttatttt atggtattta gcaaaataac tttcgatata
    45541 ttctttcgcc tttggaacag gtatatttaa atcatcagct agaccaaagt cacttttacc
    45601 atatataata ccaaagttta cagctttagc tgcacctctc aattcactag taacatcttc
    45661 cataggaaca ttaaaaactt gtgaagctgt tttggtatga atatcttcat gatgtttaaa
    45721 tgcttctatc atattttcat cctgactcat atgtgcaaga actcttagct ctacttgtga
    45781 gtaatcggca tcaaccaact tacagttatc atctgcaata aacacttttc ttatttttct
    45841 acccatttcc atttttatag gtatattttg aagatttggt tctgtagatg aaattcttcc
    45901 tgtagtcgtt atagtttgat taaatgatga atgtattcta ttactttctg gatttattat
    45961 atttaaaagt ccttcaacgt aagtagaatt taactttact atttgtctat actcagttat
    46021 cttatctatt attggatgct tatctcttaa tttttctaaa acatctgcat tagttgaata
    46081 tccagtttta gtttttttaa ttattggaag ctctaatttt tcaaataata taacacccaa
    46141 ttgttttggt gaatttatat tgaatggctc tcctgataat tcataaattt ccttttctaa
    46201 tgtagctatt atttctttaa attcaacact caattcatcc aatatacttt tgtctacttt
    46261 tataccttca tactccatat gacctaagac ttctactaaa ggcatctcta catgataaaa
    46321 aagaccatcc atactcatat ccattagact tctttccatc ataggaactg tttctttaac
    46381 tgtgcatatt atttgaccca tatactctgc taaatcctca aattctaaat cctcatagtt
    46441 tttagattta acaccctttc ctaataattc ttcttttgat ttaacctttt ttgataaata
    46501 cttcatagct attgcactac aatcatatga ggtagatgaa gttgaatcta ttaagtactc
    46561 agctattgtt atatcaaaat acatattttc taagtttata ttatatggtt ttaaagatat
    46621 ataatcatct tttaaattat atccatactt tttaatttca ttatttgaaa atatactatc
    46681 taactttgac acttcatttg aatctacata atatattttt tctccatcta cacttataaa
    46741 aatatatatt atattttttt caagtatatt accttgtcct ctaacagttt ttaaaataac
    46801 ttgtcctttt ttgtttactt catctataaa tttttctata tcttttaatt ttaatatttc
    46861 tattttttct tctacgtgtt ctgtgtcatc tgaatcgacc aaatcaacta atcttgataa
    46921 gagacttgta aatccaaagt atctaaattt atctaaaagt tcatctttat cataatcgcc
    46981 aaaaatcata ctatctaaat ccacttctat tggcacatct cttataattg ttgcaagtct
    47041 tttactttga atagctattt ctttgttttc ctctattttc ttttttacac tacctttaag
    47101 cttatctgta ttctctatta gattctctat actagaaaac tcttttataa gctttatacc
    47161 tgttttttca cctattccag gtactccagg tatattatca gacttgtctc ccataagacc
    47221 ctttaaatcg ataaattgtg ttggagtcat ctcgtatttt tcaattacag aattaaagtt
    47281 gtattcttca acttctccaa ctcctttttt tgttataaga gtagttgtat tgtctgaagc
    47341 aagttgaata gcatctttgt ctccagttac tatgtatacc ttatatccat tttcttctgc
    47401 ttttttagaa acagtaccta taatatcatc tgcctcatag ccatctattt ccaatctatt
    47461 tattctaaat ttatctaaaa ggtcttttaa tggctgtaat tgttctgcca gttcatctgg
    47521 cattcccttt cttccagcct tatactcttt atattctaaa tgtctaaatg taggtgcttt
    47581 tctgtcaaat gctacactta tatgtgttgg tttatatata tctatcattt taaatagcat
    47641 tgttgtaaat ccatatattg cattggtctt tagcccttct ttattattca tttctggaag
    47701 agcataaaaa gctctattta ttattgaatt tccatctatt ataattaatt ttttttccaa
    47761 attatatcac tcctaaaaat tatctatttt tgtaacatat atattatata ccaatatact
    47821 gttatttaat attcccataa taataatagt atattaaaat taaatatgtt gcaaacaata
    47881 tatttttttg ctataataat atacatgaca tgcccgagtg gtggaattgg tagacgcagt
    47941 ggactcaaaa tccaccggac taatactccg tgccggttcg agtccggcct cgggcaccat
    48001 taaaaactcc taaagctatt tattcaatag attaggagtt tttttatttt tgatttaaat
    48061 tttaagttat tttttgaaat tactgtgtct ttttaaaatt tatataatta tataaattta
    48121 tcttctagca ttaatttaaa aactaattta tttttatata attttctatt ttatatcata
    48181 acttattaca actttttatc taatttattg tatacaacaa cactacaaat aaattgaaat
    48241 aaaataagca atccaagaac aactaaaacc cacttgctta ttaccattac agaaaataca
    48301 ctcaatatag aaacaataaa tataagaatt acaagaacat aggacatgat ttgattagtg
    48361 atacgtccag ctttatcacg taacataatt cgtctttcat cattcatctc tatcctttga
    48421 ttttttatct tttcttcata atctactgct ctttcaggtt tactccaata catatattga
    48481 agaatcatac atacacctgg acctaaagca gctccagata atccccaaat aaaagcctca
    48541 aatgaaaact cagtaaatgt agccaataaa acaagtaaaa ttccacaaat aaaatatata
    48601 attccaacat ataacatatt ctttttcatt tttactcctc ctcataaata aatatttctt
    48661 caatactcat atcaaagtat ctagctatct taaaggctaa gatgatagaa ggattatacc
    48721 taccattttc taatgaacct atagtttgtc ttgatacttg caaaatagaa gcaagttctt
    48781 cttgttttat gcctctttct tttcttattt cttctaatct atttttcaca tctatccccc
    48841 tttaatatct caactacgga aagtctactt tccataatta tacaactata ttccatttat
    48901 gtaaagctta ctttccatat ttacaaaaaa ataacagact attttcagcc tgtaatttta
    48961 gaatttcatg ttgtttatta attttaatgt tatttattaa ttccatatta tttattaatt
    49021 ttaacttggt ttctgaattg gaatccaaac ttctgtagta taatcaggag cattgatatc
    49081 gccattggga taaagttcaa tatctggtaa attagcatac acatacccag aacttggtaa
    49141 ccactcagta ataattcttt tttgcaattc ctgtattgcc agagcatttg gcattggaga
    49201 aacacattca aatactgccc atgtgcctga tggtattaag tattcatgag tatcttctaa
    49261 tacaggctta tctgttggag cagcaatata ataatctaaa cccttactat ttgtacacac
    49321 actaactcca agcaatccac aaggttcatt atttattaac tctgaaagtt tatcaattgt
    49381 tccatttttt atgcatttag cccacaactt aggaactttc tcaaagcact cttctacaat
    49441 catgttcata ctttctttta taccaacaat acgaaaccct ttcttttcta caatacgata
    49501 ttgcatttct atatttcctt ttacataaat gcttaatgtc atcttaggat atgcttttaa
    49561 aacaacaccc tttgctctag ctgcagatgg agaaatgtta tgtatatttt gaaaagctct
    49621 attaaaagat gttggtgaat cgtaaccata cttctcagat agttctaaaa ttttgatgtt
    49681 actgttctga agttcaaatg cagccttagt catacgtctt cgtctaatat attcagataa
    49741 tggtacttct gcaatatatg aaaacattct ttgaaaatga aaggttgaac aacatgcaat
    49801 ttttgctgct tctgcataat ccactccact ttcgagattt tcttcaatat aagtaatagc
    49861 ttgatttaat ttatttatcc attccatttg atattacctc caagcaaatt atacagttta
    49921 ataaaataat atacctctct attcatgcac aaaattgtaa gcatttaaat ttataagcat
    49981 ttttcaatca atacaataaa tataaaaatt gtattataca ataaaaaagt tcaataacat
    50041 tatattataa aatgttattg aactttttat aaaaattaat ttaagtgtag ttaaattaag
    50101 tattacacta tcttatatat tacaatatcc tactatctta tagtcttctg gcactttata
    50161 atctttgtct ggagtaccta aattccattt taaatcaaac atagttgcac ttattattgt
    50221 tgcaaaataa agcataacta taccaatgtc tattttttct tcatataaat tagtatgacc
    50281 atcttttcta acagctaaaa ctacagtgcc tccatcaact ataaatctcc atggttgtct
    50341 atttaatgta gatggagcta atcttgcata gtgaaatgca tcaagaagtg ctctttcttc
    50401 taagatttct atacttgcaa catttcccca ttcgttcata taaacaacat cttctacacc
    50461 tagtctagta gaccccttat ctgttacaac ttgcatatca gattttgaat aattttgccc
    50521 agtttttgta gcatttaata ctttagcatt acttacattt tctccatatc caatagctat
    50581 aattcctgtt acctctttat ctgaattaat tccaagtttt tcttttacct tttttccatc
    50641 ttcaaaagta acccaacaag aaccaattcc aagttctgtt actttaaaga ttatactttc
    50701 tcctatgtac cctgaatttt caatgtaatt atcttttatg tcagataata ttataatata
    50761 acttggagaa tctatcatat ttcctttgta ccctgctact ttatctaaat tattaaaaac
    50821 ttcacttcta ttcataattc ttacatcaac atctatttct ggaactagtt tcttacaaga
    50881 ttctgagtat ttcttaattt cactaagata ttcttcttta atatctgtgt tcttatattc
    50941 tctaacagac tttctattta atatgattgt tttataatcc ataattttat cctccccaaa
    51001 ctagtattgt cttaattata tacccattaa tatattattt tactcattta tttaataaat
    51061 aaagattaca attttgtaat tattatttat taataatatt ccacttttac attaataatg
    51121 accagttgtg caaaatccat tgccaaccac caaataaaaa catattataa aggtaatata
    51181 aaataacaaa caaatcttaa caaaaaatta aacttttttt acacgaaaga aggcttcccg
    51241 ttgccttctt tatttttata aaaaaataag ctgtttctaa aatgatttca catttttgaa
    51301 acagccaagt tattctataa tgacaactat aatttgagga tgtgagggag agttgtcatt
    51361 ataaatttag ggtaattata ttatgtttta agctagttct ttctatattt atataataca
    51421 ttttatatat gaattttata tgagattggt ataaatgata tatgaaatta catatgttta
    51481 tattatatta aattttatta ttacattttc cacaacaata ctcatatgtc tccacattat
    51541 ttggaatatt tacaaataca aattctttac agttctcaca atactttaat atagatatag
    51601 ttccacaagt gtaacattca aatattacac aatcctcatt ttcctctact atttcaaact
    51661 ttttactatg ttcaccacac tctgggcact tgtgattatt tacattcata aatactcctc
    51721 cttattagta tagttacatg tcaaaaactt aattaatgta ttctatatta cttattatat
    51781 attctataat aaatcatatt ctaatataat aaaacaaatt aaataaaaaa aaaccataaa
    51841 ttttaaattt atggattaat tcttgtaatg ataactctat ttgaggatgt gagggagggt
    51901 tatcattaca atagggtatt atattatggt ttttaagcta gtctttctac acctcatatg
    51961 atacatatgc tatatgaatt ttatatgatt tttacataaa tattttatga aatttaaatt
    52021 ttttagtcat tttgaaattt gtaaaaagtt ctctaaaaat ccacagcatc ataaacagcc
    52081 aaaatttaag tagaacatca taaaaaaatt tgtccaataa ttttaacaag taatctcacc
    52141 tcattataat tattgacaca aacttaaata aacaatctat aaatcttcta taaatcttaa
    52201 actttccccc tattgataca caatttctag tttgtcaatt ttattttgca tttctaagaa
    52261 aatttcttca acagaattgt taaatatatt gcctaaatag attcttttat ctttttgaaa
    52321 tgaataagat tttacactac catcagaaga aatatataaa tgactccact ctgctccata
    52381 ttttgaaaac ctctcctttg tatctttaaa cctcatatct tctattttta ttgctttttc
    52441 tctgtctcct cttactacag tgtgacccct ttttattaaa ctggttattt ttatatcttc
    52501 ttttaattta atacgtgtat catcattttt tgaatatact ttccatatca ctttatgacg
    52561 ataattatct aattccttta ttaagcttct atcaatagta aaactatctt tagttaccac
    52621 aattaaatca aaatggtcta acatatattg aaatatttct ctcatacttt tattttttaa
    52681 aatatcctca ccaataacct ctataaatct acagcctttc tcatacatgc agttcaataa
    52741 acttgtgatt tcagaaaaat aatcatttgt attattatct ccatctattt ctatagtaaa
    52801 gtacaaagga gtaatgtatg atttatttcc tgttatctca aatacacttg atagtgtctg
    52861 tatatcatct tcaaacgtta agtatacatt ctcataaaac ataaaaaatt ccataacttt
    52921 ttctttcata ttatggatat ttctatatct attggataat atatttatta tatcgtcagt
    52981 agtatttttc ccatcacatt cagccagtat aacaatttgc ttccaactta agctatccac
    53041 atttccgata ctttttttat atccatcttc ttcatcataa ataggaccaa ttataatgtt
    53101 ttcttttggc cacagatgaa ccctagttcc atcttttaat ttcggatatt tattttttac
    53161 agactcataa aatctacttg tatcacccat gattctttac taccccccat agtttaaata
    53221 ttctatgcta aaaatagcac tttattttta ttaattcaac aattattcaa aattggtcat
    53281 tatatatgtt taaatggatt taacatcaac cttatttata tgttattgat gtttatatat
    53341 gttatataaa atcttatttc tcatacttca atgtaatctt aactatctct ggtttacaat
    53401 taagcctaat taaaactttt gagcctccta agcctttatt taaaatcata gtgctattat
    53461 ctttttcata ttttccccag tcatacttag gaaagaactc tctatttgga gataatacac
    53521 ctccaacaaa aggtattctt attatacctc catgaacatg tcctgctaaa accaaatctg
    53581 ctccccattt tgcatatttt tcaaagaaaa atggtgtatg tgctaaaaga atgttatatt
    53641 cattttcatt aactttacct agattgtctt ctacaaaatt gtcacttagt tctaattttt
    53701 tgctattagc aaataaatat ggatagcatt ccaatggtat aattaaacca tataaattaa
    53761 gatggctatt acctctatat attcttacag attcattttc catatttatt attttctttg
    53821 aatatagttc cttaaaataa tccttatata gatgtttata cttttttatt aaagattttt
    53881 gttcatgatt tccaattata tgatatactt catatttttc aaccaaatta tctattaaat
    53941 ctaatgcaac ttgaaaattt ttattttctc catctactaa atctcctgtt ataaatataa
    54001 catctgggtt taatgattca attttatcta tcaatacctt attattttta tcaaacacct
    54061 tattatgtaa atcactcact tgaactattt taaagttatc aaattccttt ggaatttttt
    54121 tgttgaaaat agtatattct gtcgtttcta tatgctgagt ttcatactta tacagaatat
    54181 acaataatat taatactaat actgtcattg aaacctttat aatcatattc tcttcctctt
    54241 tattctattt tgttaatatt attataatgc ttttatgttt tttttaaaac aataacatca
    54301 tcacatacat ataaatcttt tcgacattat aaaaataagt tatccttttc taaaattttc
    54361 atttatttta gaaaaggata actataaaat tatctataaa cctctatatt gtgaaatata
    54421 gtttttcctt tatttaaatt tttatatata tgctctaaag ttccatcaaa cctaatagaa
    54481 tgtccagact ctaaaatata agttttccca tccacattaa ggtcaagttt accttctatt
    54541 acgagtacat actcttctaa aacatgactg tgtgtagatg aaacatgagt acagttttcc
    54601 tcaagctcaa ttataaaaag ttcaaacctt ctttgagggc taaaagggta tattggatat
    54661 aacttcatgt tccctttttg ctcaacaata ggctctactt cttctttctt tataacctca
    54721 taggtatttg tattttcatt taatagtgta gtaaaattta ttttaaatcc agatgaaatt
    54781 ttccataaag tagatactgt cggacttgat tcacctctct caatctgtcc aagcattgct
    54841 ttactgacac ctgtcatctt tgaagctttg tctaaactta tgcccatttc ttgtctcaat
    54901 aaccttaaat tttctcccac attaggaaat ttattatcca tgttaaaatc ctcctgatag
    54961 ctatttgtat tctatgattt ttactcctgt aagttctact atctctttta attttaacat
    55021 atgattgtta caaatttcat caaattcata tatataatct tcaagcccta atgccttata
    55081 tttatcgatt ccaaatttat gatatggaag taactccatc ttgcctcctg gaacattttg
    55141 tttgacaaat aatgcagtat ttcttatatt ttcttcacta tcatttactc cataaataat
    55201 tggcactctt ataaccatag atttattcaa ctttgaaagc ctacatatat tatctaatat
    55261 aattttatta cttactcctg tatattcttt atgaatatta tcatccatag attttatatc
    55321 tacaaatatg tggtctattt tctcaaatac atcatttacc ttattccaat caaaatatcc
    55381 acaagtttca attgcaatat ttatgccttt atcataaaaa atatcaacta attctcttaa
    55441 aaaatcaatc tgaagtgtag gttcacctcc agaaaaagtt atccctccat tagattcaaa
    55501 gaaaaatata aaatcttttt caacttcctc tactatttct tcaacactca tttcttcggt
    55561 cattatacaa atggcatctt taagacatac cttgatacac tctccacata aatcacattt
    55621 attatttatt tgcgctctat caaatagtga acttatattt tgaggacaaa catctataca
    55681 tctattacag gatacacatt tatctttcat aacacctaat tttactatgt tactccagga
    55741 atctggatta gaacaccact tacattttaa tttacatcct tctaaaaata tagtagtcct
    55801 tattccatct ccatcattta ctgaaaaatg ttgtactttt acaactctac cttttttact
    55861 cataatctac ctcataatta aaaattgcta tgtgaatttc tagctattat agcatcttgc
    55921 atttctcttg ataaattaac aaattgagta ctatatccag caactctcac taataaatct
    55981 ttatattctt ctggattttc ttgagctttt aatagagtat catttgatat cgtattaaat
    56041 tgtacatgga atcctcctaa agcaaaatat gatttaatca tagatgttag atttctaagt
    56101 cctctttcag tttccaccaa atcttgattc agtcttaaat ttagaagtgt tccaccagta
    56161 tgaacatcat gatttatttt tgatgcagat ttcattgctg ctagtggact tgttgtatca
    56221 gtaccaacaa atggagaaac tccctctgtc aaaggttttg tcgcttttct tccacaagga
    56281 gttgcgccta cgatttttcc agttggtaca tagtttgata tacccataaa tgcactatta
    56341 aatttagagc caaaaatatc cttgtatttt ctagtttcag tataataaaa atcagaaact
    56401 tcaattgcta atgaatctac ataatcatta tcatttccat acttaggaac atccaacgca
    56461 agttttctta attcttcata accttcccaa tcattattta gtgcttttgt taattcttct
    56521 aacgtagtca ccttatcctc aaatactaat ttttttatag ctgccaatga atttgaaact
    56581 acacctaacc ctataccagt taatacagga cctatattat attttgctcc tcctttactt
    56641 aaatcaactc ccttatccaa acatccatct acacaagtag ataaaaatgg tcttggtacc
    56701 atttctttat gaatttgttg agcaacagta gttcctataa cagaactttt tacaagatat
    56761 gctaattgct ttaaaaactc atccttaagt tcttcaaaag aagtaaattc tgtgatattt
    56821 tttgtatcta accccatttt ttctccagtt aatctactct taccttcatt catagcatat
    56881 tctaaagctg ctgcaaaatt gatatttacg gctgaagtcc actgtcctgt ttttctaaaa
    56941 tgaggaacta cacaaccaca gttactccaa tctctagcat cttctgcatc atatccatct
    57001 tgtaataaca tttgtgcccc tgcactatcg ctgtgtatag cagggaaacc agttccttgt
    57061 tttaccaatt tagcaactgc cattacgaaa ttgtctggtg ctccttgact cactctaaca
    57121 cttaatcctg gttggtgagt ttttacactt tctgtagcct ttaaacacat atatgagata
    57181 tcattcgttc catcagtacc atttctcttt ttaccaccaa cagtaagatt ttggaattga
    57241 ttatatcctg caaagtaatt tgctgtattt gctgatatag tccataccca ttctgataac
    57301 ttaatccaaa gtgcttctat caattcttga gcttctgatt cagttatttt accttctcta
    57361 gcatcatttt cataatatgg atacatatat tgatcaaatc tacctaaatt taatgccaat
    57421 ggattttctg atagaatacc acctaattga acaaaccata caaattgtat tgcttcataa
    57481 aaattagttg gagggtttgc tggtacattc atacatatct ctgaaatttt tataagttct
    57541 aactttctct tttcatctgt ttcttgctta ctcatctctt ttgcaagatt tgaatatctt
    57601 tgtgccaatg tcataatacc ctgtgcaact atagaaacag atttgtaaaa atctatcttt
    57661 tcaatatttt ctgaaactga tatatctaat tctttaattt ttttatctgc atcttcctta
    57721 atccctttat atccttttac aaacaatata tcttgataat ctggtgttac ttcaccaact
    57781 gcctgtctcc acttagaatc attatctatt attcctgtat ctactaatat cttagctgta
    57841 tcttctggga ttcttgctaa gaaaacttct tccaaagatt ttcccttcca atatggaaat
    57901 atttcttttc ttataaattc tatttgttct tttgatatta catatgggtc ttgagttctt
    57961 ttatcaaaag tatccatttc tttgtctacc cattgccaag aaaactctgg tgtcaatatc
    58021 cctgttcttc taaattttcc tgctgtacct actattaatt cattttcaaa gatttttata
    58081 ggaagttctt tacatgtctc caaaaaagct ttagctcttc ttatacagat agcttctccc
    58141 tcagtttttt tatgtgattc tgtaaaaatt ctagcccttt cacaacatat cataggttta
    58201 gaattaatat attcttgtct aaatgcttct attctattag tttgactcat ttaaaatccc
    58261 cctttggata atatatacta catttttgta tgttataaca tactttaatt atattatact
    58321 gtcctttagc ataaaatgga agcaaaataa cttatttttt ttcatctacc ttgaacacct
    58381 atatattaat actttttttg ttaaatttat aaaatctaaa aaaattttct atgatatatt
    58441 ttctatattg ttatagttat gtctaatata ctaatgattt gaaatatcaa atttgtatac
    58501 tagacttagt tttaaaacct tagttgattg tttaactttg ttaacttcaa catgtatatc
    58561 cttcatataa ggaagctcta caacacctac tcccttatta aagtcttctt caaccataga
    58621 aaaaatttct ttctcagtta agttcgtatc agtcaatgat ttaaataaat tgtatataaa
    58681 tttaacatat ttatcactct cagataactt atcatcttct ggatactctt tagcacagag
    58741 aatatctatt gttacttttc cttctttatc gtcttcagac atagaataga ataaacttcg
    58801 aatatttttt tcaggtggtt tttcagcacc atttatagat actacaaagc taccatctga
    58861 ttttgagtta gtaatactat aaccactgtc tattatagct ttcgaaaatc tttgagataa
    58921 atcttttttt acttcttctc tacctttcgc atcattaatc ttttgtgagt aattattaaa
    58981 tagctcaata gattcatctt ttttatcttc aacttgttct ttcaatgaat ctttactaat
    59041 ttgttctgag ctacttaagt tcttatcaga tacaggagac atacacccta ccatcaatgc
    59101 taagctaaga tttaaagcca caattattgc cactctattt atattccttt ttactttcat
    59161 acacaatcct cccatcacac taaccgctct aaagtattat tcattgcact agaatatatt
    59221 tatattttct ttatattaaa gatttattat tcaatacata tcaccttcct atccaattct
    59281 tataacttac tattagtaaa attataagct ccttaataca gaaataagga tgttatcttt
    59341 tgttattaaa agataacatc cttatttttt tgtatcaata catatgtccc aactggtaac
    59401 ttaatcgccc caactgtcag tatcttggtc caatggtata tatatattta gtataaattt
    59461 atcgatacta ttttcaaata ataattctcc attatatttt tgtaaagaag atttaatact
    59521 ctgaatacct attccatgta cgaacttatc cattttgttt gttaacaata tatttttatt
    59581 aaaagtaagc tgatttagtt tactattttc acatttaagt acaaaaaatg accttgttat
    59641 agttccttta attctaatat atttattaat attttcatcc actattttat cacatgcttc
    59701 tattgcatta tccaaaatat tagaaaatat gcttgacaca tctataggtt ttacaaaatt
    59761 tacttttgaa aaatttatag agcaagtaaa tttaattcct ttttttaaac atacttcact
    59821 cttttcgttg attataatgt ctaatatcat atttcctgta ttatagatat atttaaatgt
    59881 ttttatttca tcttttaaat tgttaacata ttcattaatt tctttgctat tgtttctaag
    59941 gttgtctata caataaatgt gattatttat atcgtgatat agtttcttaa ctcgcatatg
    60001 agattcttga atacttaaat aatgcgcata ttgcatatct aacttatttt ttattaattc
    60061 agcttgagat tttaatctat tctcttttat tatttcttta aacaatagta taagaaatat
    60121 actactagct cctaccaatt ttggattaac aaaattatca aaatagtatc cttctgaatg
    60181 taatgaccca aaccgttcta atttttttaa tacataattt acaagcatat tcattgtatt
    60241 aactaataag gcaaataata aatatacata atttctctta tcttggctaa ttaattttat
    60301 agactttcta aaaaagctaa atataagata tataagaata attattaaat tactatatat
    60361 ctgaattttt atagattcta agtaaggtac taataaagat tctttagatg aaataacatt
    60421 acctgtaatt gcaaaaaata gtattctata tataacagca tccaaacatt tataatatac
    60481 actaaataga taaaagaaaa tggaatactt aatataaccc atcttataaa aataattata
    60541 gtatcctccc caagcaataa atgctaatat ataaaataaa tagtttatat tactaaagta
    60601 atttcctcca ttaaataatc tacttatctg aattataata taaataagaa acaagacaat
    60661 atagaatact attttttcat tttttttact atccttttta taaattaaaa ttccgttcat
    60721 tatagaaaac tgtataaata tagataaaac tactaatagc tcagtcataa agtttagcat
    60781 attgtatcac caagaaattt taagaatttc tccttaactt ctttatatct atatctacta
    60841 ataggtacct cttctccact ttccagtatt gcagtattag gctttatatt ttcaacatat
    60901 cttaaattta ctataaaact tttatggcat cttataaatt tatatggatt taattctttt
    60961 tctattttgc ctaaactata ttttatatca aaattcttgt ttattgtgtg tattagcata
    61021 tctttttttt gaacttctat atattttatt tcatttaaat aaatcttata tgtattagac
    61081 ttatttttta ttgtaatatg actttcctta tttatttcaa tatctttgat acaagttagc
    61141 acatgttttt ttagttcttc caactctatt ggctttagta aatacctata agctcttacc
    61201 tcataacctt cttgcacata atctattaat gaagttacaa atattatttc catttcattg
    61261 tctacttctc taatctttct tgcagtatcc attccattta atttttccat ttttatatca
    61321 agaagtaata tatctatatc ttttaaatta ctttccagta actcttctcc agatatatac
    61381 ttttgtatct catattctat acttatatct tttaatatat tctcaaggta atcttctatt
    61441 aaaagttgtg tttctttttc atcttcacaa actgctatct taatcataaa atgcctcctt
    61501 acataatttc tagttaatac aattaaaata tttataatat atttaaagat aattttgtat
    61561 atctgatact ttaggataac atttttaaat tatttttatc aatactcaat cccatacaac
    61621 tattatttga tatttcaatt taaagacaga aattactata attaaaaaca gtacttactg
    61681 acaaaagaag atgtcttaaa atattaaaaa aataatttta ggacaccttc ttttatttat
    61741 ttaaactttt taagccttaa ataatacatt aatctcctat ataattgtac tgcatataaa
    61801 atcaacaata taatctgtag tacaatagca gttacagatg ctccataacc actatataaa
    61861 tttcttattt caatattcaa taaatatata aatattacta ctaacataaa gaatataaac
    61921 atattcataa ataaaattga ctttacttta tttgttttat cagaatcact atataattta
    61981 ggaggtatgt ctttgtattc tttcgaccat atataccatg cagatgtacc cataaaacta
    62041 ccaatactcc taaatacaag attccagcca tttgatttat gttcatcaaa ataattattc
    62101 tctacatcat agtagtaatc aacagtgtat tttatttttc ttggacttcc cttatgaaaa
    62161 taaaatattc ctccaaattt atttatctta tataaattat atcctttagc ttcaatatct
    62221 tctaaccatt tctctatctt atcaggtgaa ctataccagt caaatttgaa ttttattttc
    62281 ttttccatag cactcattct ccaaaatgat atttttaaat agcttaaaaa tctatttaaa
    62341 taattatatc attttgatac taattttagg ttacaatcat atatttaaaa gttatttaaa
    62401 tagtaataaa ctaatagcca taacacccat tcctgcaatc aatccataaa tagataaatg
    62461 atgttccccg tactctctag ctgatggcaa taattcatct agtgatatga ataccataat
    62521 tcctcctaca attgcaaata caattccaag agttatatca tttaaaaaat ttctaagaag
    62581 tacatatcca ataatcgctc ctaaaggctc agacatacca gataaaaagg aataataaaa
    62641 agctttcttt ttatctcctg tggcataata aactggtaca gatacagata taccttctgg
    62701 tatattgtgt attgcaattg caattgctat cggaatagct attgtaacat catcaagagc
    62761 tgatataaat gtagctaatc cttcaggaaa attgtgaatt gctatagcca ttgctgtaaa
    62821 tatacctgtt cttaaaagag acttattttt tttgatattc ttttcttcta tattctccat
    62881 tttctttatt tcatgtggat tttcttcttg tggaattagc ttatcaataa cagcaatgat
    62941 agccatacct ataaaaaaag ctattacagt tgaccaactt cctaatttct ctcccataga
    63001 ttttgtcaaa gcatcttgtg ctttaggaaa aatttctatc atagaaacat aaatcataac
    63061 accagcagaa aatcctaagc ttatagaaag aaacttagta tttgtttttt tagcaaaaaa
    63121 tgctatacaa cttcctatac cagtagataa accagccaat aatgttatca aaaatgcaaa
    63181 tattacatta ttcaaataaa tcaccttctt tttaattgat attgattatc attttcttta
    63241 tgctatcata tatattttat atagtcaata tttataaaaa atatacacaa taaaaaagca
    63301 gagatataaa cttagtctct gctttttctt tatagtatat taaaattatt tatttaagaa
    63361 atccactgca tattgcacat ataaagcagt tccaatttct agagcatctt catctatatt
    63421 aaagcatcca tgatgatgag gataacaagc accttttgac tcatttctag ctcctacaaa
    63481 tgctagtgca ccaggtgcta tattcataaa ctcagctaaa tcttctgctc ctgttacttt
    63541 ttcaaatagt gttatacagt cttctccaaa tagcttaatt gctgcatctg tagctatctt
    63601 tgaacattct ttgtcattta taactgctgg tgttaagtac ccatactcta attcagcatc
    63661 tgctctatat gcttctgctg tagattttgc tatacgttct aaaattccag gaatttgctt
    63721 tctaagctct ggattaaata gccttattgt accttctaag atagcttcac tcgcaattac
    63781 attaaatcta gttccagaat ttaaaactcc aacactcaca actaatggtt ccagaggact
    63841 tacttctcta ctaaccatag attgtagatt cataactatt gctgaacttg caagcactgc
    63901 atcaacacct tgatgaggaa gtgaaccatg accacctcta ccttttacag taattttaaa
    63961 gaaatcagca gaagccattc ttggtccttc ttctaccgat atggtcccag attctacatc
    64021 agtccaaaga tgtattccaa acacactatc tacaccttcc atagcaccat cttgaatcat
    64081 agctcttgca cctttaccaa cttcttctcc tggctgaaaa aataatttta cagttccatt
    64141 gatactatcc ttaatatcat ttaacacttt tgctgcccct agaagcattg atgtgtgacc
    64201 atcatgacca caagcatgca taagtccttc atttttagat ttgtattcta catcagtgca
    64261 ttcaacaact tgtagagcat ccatatcacc cctaagtgct acagtctttc ctggattatc
    64321 tccttttata gttgcaatta cacctgtacc tccagctgat acatatggta tccctatttt
    64381 atcaagttct tctttaactc tctttgatgt tctaacttct tccatacttt tctcaggatt
    64441 ttcatgaaat tcccttctaa gcttaattac atagtcttta taactctttg ttatttcttt
    64501 aatatccatt ctatacctcc aagtagtaca cattcttctt atttaaaata ctttttatca
    64561 attaaatact atattagatt tacaaagata cctgctatta ctacagaagc tattgtaact
    64621 gtagtaaatc ctccaacaag catctttgga agcattttat ccattaaaaa ttctttttct
    64681 tctggtgttt cagccaaagc ctttactgcc tcttcagtta atatatagtt tggtggaaaa
    64741 ccataaagtg atgtaagcga aactgaaaaa gccatttctt tactttcacc taaaagctta
    64801 cctactataa tagagaaaat tcccatacct attacaccaa atattatgat tcctacaaga
    64861 ggaactgcca tttcaacaag cattgctggt gtagcttttg ctaaccctgc aaatataaaa
    64921 gccatcaatg atgtcattaa ccatccaaat gaaccagatt tattaagtgg ttttctatca
    64981 actattccaa gttctgatgc tattacacca aatattaaac atataacata tcttgataca
    65041 acttcatttg taagatttgt aaattgtact gctaaccatg ctacaaatcc taatctaagt
    65101 attatcatat atgtcgtatc atatttttct ggtaagtctg gtattatctt aaatctgctt
    65161 ttttgttcag gtaaatcctt aactttttct tcatctgtat ttacagttac ttttccactt
    65221 ctaaagtctg ataaaagtct ttttccttct tttttaagca ttaatgctgt aataggataa
    65281 cccgcaaatc cttgtgcaac atacatcaaa attgcaagta ctgataaact tgcaagacct
    65341 tttgctgtag cagcatctgc catcattata gatgcaacta gccctccagt aagaggaggt
    65401 gtagctatta ctgctgtatc ccatccaaat actactgtcc ctaatgccaa agcacctaca
    65461 catattccta ctattcctgc caaggctatt actattgttt tccattgacc tgctaattcc
    65521 ttaatactca tcatagttcc catatgagtt attaacaaaa gcatacctaa ttgagctaat
    65581 ggtgttccta aagcggctaa gtccacaata ttttctggga aaaaagtcca aaatcctact
    65641 ataaatataa ttgctgatac aaaaaccgac ggaacaaaag ctttagtttt tgctgaaact
    65701 atatctccta tcgtcagtga tactaaaact agacaaaaag ctgttattgc ctccatacaa
    65761 aatcccccct cataataaat atatttttat aaaatgtatg tatagttatc cattatttta
    65821 ctacttttga aaaacatttc aagtcaaaat tcgatttttt tcataaaatt cgataaattc
    65881 cataaattaa agttagtttt ctaaattatt ctttttgtaa aaacgttatc ccgaccattg
    65941 gctatttaac tctattctta caaagagaat taaatgtaat ttgcaaaaaa taaaacatag
    66001 gatacatttt attcataaaa catcttataa atataaaatg aattgtcttt atgaatctta
    66061 atatatccta tgtttgtaag tttaatgtgt atgttagcta tggtgtaaaa tttgtatact
    66121 agttattgtg taacctacta tatactccat ttttgtttac tagctcttca tgagtacctc
    66181 tttcttcaat tcctttatcc gtcaatacta tgatttcatc agcatttttt atagtagtca
    66241 atctatgtgc aacaactaaa tttgttctat ctttacttaa ttcctctaaa gactcttgaa
    66301 tttctctttc tgttacattg tctaaagcag atgtagcctc atccaatatt attattggag
    66361 gattctttaa aaagattctt gaaattgaaa ttctttgttt ttgcccacct gataatttta
    66421 cgcctctttc tcctatataa gtatcatatc catctggcaa agtctctaca aagtcatgta
    66481 ttctagcttt tttagcagca gctatcattt cttcatctgt agcattaggg ttcccacaaa
    66541 gaatattatc tcttatagtt cctgtaaata aaaatacatc ttgttgaact atacctatat
    66601 tttttctcaa tgattttaaa ctaacatctt ttatactctt tccatcaatt tttatatcac
    66661 ccttatcaaa ttcataaaat cttggcaata gattacataa tgtagtcttt cctcctccag
    66721 aaggtccaac taatgctata gtcttaccag cttttataga taaacttaaa ttatccaaaa
    66781 cttgagtctt atcttcatat gtgaaagata tattttctat ctcaatgtca ccttttacat
    66841 tttcaagttc aataggattt ttagcttctt tttgatggtc ttgttccatt atctctatga
    66901 atcttttaaa acctgtcata ccattttgat attgctctgt aaagtttatt aattttttca
    66961 taggttgtat aaacattttt acatatagta tataagcagc aaaatcaccc aaagtaatct
    67021 ttcctatata agtaaaataa ccaccagcta ttacaactac ccactctaag atatccatgt
    67081 ataaattcat accagagtaa tattctgcca ttaccttata agaatcttgt cttgctcttc
    67141 taaataattt attgcttctt acaaacttat ttaactcttc tttctcagta caaaaagact
    67201 tagttacctt catacctgct atactatttt ctaaagtagc atttacatca cctatagtaa
    67261 ctctactctt cataaaagca atattcatct tatctttttt agctattgca aaccaaatta
    67321 taaacggtaa tatagcaaat attataagcg taagaggaat atttatatct ataagtataa
    67381 agaatgaacc aaccaacatt actatagaaa tgaataaatc ttcaggccca tgatgtgcaa
    67441 gttctgttat atccattaaa tcatttacta ttctagacat agttactcca gatttgttat
    67501 tatcaaaata cgtatttgga agtctttgta agtgtgtaaa tacctcattt ctcatatcag
    67561 cttgcatatc tacaccaata acatgtcccc aatactgcat aaaatagtta agccctgctt
    67621 ttgctataaa tataagtata agtgctactg caaaaactac taacattctt aagtttttat
    67681 ttggaacaac gtcatccatt atatttctag ttatcatagg ataaactaaa tcacataagg
    67741 aaaatagaaa agctgctata aggtctagtg taaaaatttt cttatatggc ttataatatt
    67801 tgacaaattg ttttatcata agtattaaat ccctccttta ttagtacttc taaaaaatac
    67861 ccataaatta gtataacata acaataactt taaatctttt ataaacttac aaagtaataa
    67921 caatcttttt cataaaattg aagatttata tcatatagtt gtatacttga aacaacataa
    67981 aaagagctat atctctatat ttaaaatttt ataaagatac aactctatat ttaatactaa
    68041 atttttttta taaatacaaa actacttcaa tgcatttaat atctttttat ctaatgctgt
    68101 tgtatttata cctgttatat atcctgttgc ctttattgta ggtatatcat aagttgttgg
    68161 tagtatagta gtagatacga ttaaatcagc accttcttgt tttgttgaac attcagcaat
    68221 tttacattgc tcaacttctg cttgtatatt attttcttta accaatcttt ctactctgtc
    68281 acaaactatt gttgatgttg cgattcctgc tccacaggct actaatattt ttttcatata
    68341 ttgtcctcct acaatttctt taatatttta taactcaaaa taaaattgat aaatttctta
    68401 tatctttatt tatataaata attatatcat tttatataag aagaacatct taaaattatt
    68461 cttttaatat gttttttatt tcaacattgc ttatacttaa aatttcattt tttatacaag
    68521 actctatgta ctttgatata tttttataat catttaaatt aaactgttca atattcaatt
    68581 tatattctat atcactgaca atacctatca aatcagactt attagataaa atatcctcat
    68641 acttaccttt tctagttact tccaatcttt taaatctata atttttatat ccttctatga
    68701 taatcaagtc catatcttca tataattgaa tcattttata taatggattc ttctctttta
    68761 gttcttcaat atatgctact cgtttatctg atattataca gacttttctc gccccagatt
    68821 ttctatgttt ataagtatct tttccttcct catccatatc aaaatcatga caggtatgtt
    68881 taataactcc aacacgatac ccttttttat ttaattcttt tattatgcct tcaatcaatg
    68941 tagttttacc tactcctgaa tatgagacaa ctgacaatat attatacata aaattgtgtc
    69001 ctttcataaa actatctaat aacaacatcc actaattgat tttcttttat tgtctcattc
    69061 tttttaatct taatcataca attacttctt agagttgcag ataatctagc ttttgcatct
    69121 ttcttatcat ttagctctac atacaattta ccttcacttg tatatagttt tccacttaca
    69181 aatctatctt tatttgaaag tttattaaat tctcctttaa atatagcttt tatatgatgt
    69241 gttcccttct tatatgttaa atactcaata acaggaacta tcacattatc aaataccact
    69301 attgctgcat gtggattacc agaaagacca aataatagct tttctcccaa tgtacctaca
    69361 taacaagctc caccaggttt aatgtttatc ttccaaaata attctgttgc ccctattttt
    69421 ttgaatacat ctggaattaa atctttatct ccaacagaaa caccacctgt ggtaattaaa
    69481 aaatctacac tctgtaacat attctttacc tttttttcta actccaatat atcatcagaa
    69541 caattgcata ttgtatctgc ttgtattcca agttttaata atcttgaata taaggtatat
    69601 ctattactat cgtatatttt accattctct aaagtctcat ttatatcttg tagttctgta
    69661 cctgtattca aaattccaac ttttaaatca tcataaacag ttactttgga tattccaaga
    69721 cttgctaata ctccaatacc atcatatcct atattctgat ttttattaat aatcaattgc
    69781 ccctttttta tatcctcacc cttaaatatg taattatcgt attcctttaa ttttatattt
    69841 aaagttatca tatcacttat aactgttaca tcttcttttt ttattacaca atttgcaccc
    69901 tgtggtatct ttccaccagt cattatcttc actgcttcat ttttatttaa taccctatta
    69961 aatacatctc ctgcatacaa agtccctata acctttaaat ttctattttc agaatttgca
    70021 ttatatgcat aaccatcata gggtgaccta tcaaatggag gactatcaat tgttgaatat
    70081 atatcttctg caactacctt atttactgca tctataagat ttactatctt gaccctgttt
    70141 attggtaaaa catttttttc aataattttt atggcatctt ctaattctat cattttaaat
    70201 actccccaat atatttttta tttaagatat ttctatgtaa tatattatag attataaaag
    70261 ttggaaatac ttttatctta tatttaatta taactaatag ttatctataa gtgcagttca
    70321 aattttataa atctaataaa aaaactgttc ccagctagaa atttccttct atcttgaaac
    70381 agcatcatat gctttagaat attttattct aataaagttc cttttattat ttttacaatt
    70441 ttatcacttt caatagtttt tatagatttt attttgttat ccacaatact tattgtaagt
    70501 acctcttttt ttaatatttt gttatcttct ttcaatctat aactcttaac tactttactg
    70561 ccttcatgat tatatgctgt taaatcataa ttcgcatctc ctacaatttc atttattctg
    70621 gaatcttcaa caccaacata ctctcccagg tcaatatgtc taaaattttc tagtgataca
    70681 gccgattttt catggtcact tttttcaatc actatactag attcagcatc aatgactgat
    70741 ataccttgtg atgagaaaga attggtttca acattgacaa ctttattttc gttaatatca
    70801 acatataaag cacttccatc tagttcatca tttccagtat attttggata aactaatgtc
    70861 atataacttg atgtatttat atcttgcatt gtatttgatt cttttaaaac tttaggtttt
    70921 atataataaa atgtattata aggtataccc atattcttta taatgtactt ataatcttta
    70981 ttcataattt cattaacatc attttgaact tttgtcatag ttttttgctg tgttgcttta
    71041 cttgctactt gatttttctc tttagtattt tctttatgac atccaacaag tataatacct
    71101 aaaatagtta cacaaactaa tgaccttttt aacttcataa atcaatcctc ctttcttaaa
    71161 ttttatagta tttatctata tctcaattta cagttatctc ttttttcaat aattatattt
    71221 attatattat aaaataatta tataatattt atttgaattt aataagatta agaagctaat
    71281 tgtaattttt ctgtaataaa aaacacttta aagttgaatt ttgaaaattc aatttacgat
    71341 atttttattg taagtacctt acaacattat accaaattat tcctaaacaa tcaaaaactc
    71401 catgaatatt taaaggtttt ctattttaaa aatcaccttt gactattaat ttatcaaata
    71461 tgttataata gttttagata atttaaggag gattaaataa tggattttaa acaacttgaa
    71521 gtatttgttg ctgttgcaaa acatcagagt ttttcaaagg ctgcaagaga acttttttta
    71581 actcaaccta ctgtaagcgc acacatacag aatttagaga gagagctaga aactgttctt
    71641 ataaatagaa gcaacaaagt tattacactc acaaaatctg gtgaaattct ttatgaacat
    71701 gctatatata tattgaataa ttgcaaacgt gcaatttatg atataaaaga atattcagga
    71761 aaaatagaag gtattataga tatagcatgt agttccatac ctgaaactta tattttacct
    71821 gattttatga agagtttttc tatgagttat ccagatgtaa aattttccat aagccattat
    71881 gattctcaat atgctatatc agaaatttta aatgaacgaa taagctttgg attagttggt
    71941 tctaaaatca ataatcctca aatagagtac ctagacttat tagatgatga acttgttctt
    72001 atcactcctt cagattttaa aattgataat aaaaataatt gtatcgatat aggagaattg
    72061 gcttatctaa attttattat gagaaaagaa gggtcaggta caagaaactt aatactaaac
    72121 acacttagta aaaataactt tccagtaagt aaattaaatg taatcgctca tgtagaatca
    72181 aatgaggcta ttaaggaaat ggttagatta ggtcttggag tgtcctttat atcgtacatt
    72241 tcagctatcg attatctcaa tgcaggtaaa ataaaatgtt ataaaataaa ggatgttgat
    72301 tttactagaa agtttttctt catttactct aaaaagaaaa ctttttcccc attagaagat
    72361 aaatttctaa acagattatg tgagtatttc gaaattataa tataataact ttaataaagt
    72421 agtgcttaat tttgagttta taactaatta ataagctaat tataactatc acataaatgc
    72481 ttataaatta ttatgaacca tctttctttt ttatttaatt tagtcaaaaa atccctcgtt
    72541 caaatgaact tgggattttt ttatttatac tactccaata gcagccaata ctatacaaat
    72601 aatcataact gaaattaata tcgtagttgt ctttaccttt tttcctaata accaatacat
    72661 aataccgaat atcatagctg gaagcataca tggcattatt tggtctaagt aagtttgaat
    72721 aggctctgcc cattctccac tacctacatt aacactaagt tttaacatta cattagatgc
    72781 agtcatacct ccaattacca taagccctaa cattgaagct gcttccataa cttttgaaac
    72841 tatacttgaa ccactcacat ctttaaagaa ttgagttcca tacttaaatc ctttatctag
    72901 acatatatag cgtataataa aatgaggaac atttattatt aaaaggaata aaatcggtcc
    72961 cattatgtta ccctgagaag ctaaagctat accaacccca gctgctataa gctttaatgt
    73021 tccccagaaa aatgaatctc ctatcccaga aactggaccc attaaacttg atttaacagc
    73081 atttatacta ttagcatcaa attctttatt ctttgcattt tcttcttcca tagctccaga
    73141 tatacctacc aaaagagtac ttatatgagg agtaactgac ataaattcta aatgtctttt
    73201 taaagcctta gatttctttt ctttatcatc tttatataat ctacggatta ttggtgccat
    73261 catgtatgca tatgctatat tttgcatacg ttcgtagttc caagatgaat ctaatgtcaa
    73321 tgaccttcta aaacatttcc aaaagtcttt cctcgttatt ttactatctg gtgaaattgt
    73381 ctctaatttc ttagaactcg ttgtcatcta ctattacctc cttctctcct acaaagttaa
    73441 catatattaa agctattgct aatccaaaca atgcaactcc tgttactgtt atgtttaggt
    73501 aagcaaccaa tataaatcct aataataaaa atgctactgt tttcttatta agcatcattc
    73561 tagctaacat ggcaaaacct attgctggaa tcacgcctgc tgcaacatcc attccatgag
    73621 ttacatatga tggtataaat gaaagtattt tttctattac tggaacacct aatgaaaatc
    73681 ctatacctac tattattgct aatattaatt tatttcctat accaaataat aattgcacac
    73741 gttctacgcc ttcaatattc ccctcttctg cataacggtc agcaatatga gctccccatg
    73801 taagtactac tgtcattaag aagttatcta taagcaatac tagagttgct ataggaactg
    73861 caagtacaac tgctgctgat acatcttgac ccgttaatat tacaaacgct gtggcaataa
    73921 tagaaccaga cacaaaatca ggaggattac ttgccccaac aggaaatgca cccataaata
    73981 ctaattctaa tgttgaacct attactatac ctgtatgaag attacctagt gctaaaccaa
    74041 caagtggtgc aacaactata ggtctattat gcattgtaga acctacaaaa ctatgcatat
    74101 atgcaaagaa tgcaattaga gttatcaaaa taacttgtgt aaattccatt ttcatccccc
    74161 taaaattata ttaatttcat tacatttgta gcatcatcat caggaactaa ttgtacaaat
    74221 acatttacgc cttctgaatc taactcttta atcatcttta tatcatcttt tgatacatgc
    74281 actgctttag atatattttc acgattatca tctgattttg ttccaccaag gtttatagat
    74341 ttaatagctt ttacctcttt agcaagtctg taaacatctt ctacagattc acaaagtatc
    74401 aataagttgt atttatcagt aacacctgag ttaagtgctt ttatagaatc tgctatgctt
    74461 ttcattacta acttaacatt agatggttta gccattttaa gtcctgccat tcttaattca
    74521 tcttttaata agtcatcact tgctatcaat atacagtctg tacttaaaaa ctttgtccat
    74581 gtaaatgcta cttgtccatg tataagtctg tggtctactc ttactaattt aatcattata
    74641 attcctccct aatttttttg atttcatcca tgaatgtttt tacgtgttct acactaacat
    74701 ccccaaaatc tttgtaatta tctttaaagt aacttcctat tattgccata tctcctaatt
    74761 taagctgttt ttttgcattt tctaatgtaa ctccagcagc tataaccaat gggaagtctc
    74821 ctaaattttt acgaaacagt tctatttttt ccattgatgt ttcttgacct gtagcatttt
    74881 ctgtaactgc tatagcatca catcttgtca ttcctatttt taaatcttct tcaacatcat
    74941 tttctgataa tactggctga tatttaaaac gtacgcctcc aattaaatac gctggacatt
    75001 ttgaacgttg taatttaaaa aactcttcta aagtagcttc atctctaggt ttaacatgac
    75061 ctactacaga atcaacctgt atataactag cattatattt tgttgccagt tcaaatccca
    75121 tagtatcaac atttaaacag tttactccat atggtattga taaattagct tttgatacat
    75181 attcaagtat tctttctaaa tcataataat taccatagta attttctaac attattccat
    75241 ctacaccatt ttcttcaaag attgtaatct cttttttagc tctttcaaag atatcttctg
    75301 gagtatctcc ttttaagtgt atcattgcta taattggttt tttactttta aatactgata
    75361 atattccctt ttttttcata aactaaaata cctcttcttc ttctttaatt tgtaatgtca
    75421 cgctttgtat tcctcttcta gattcttcca ctaattggtc tatatcttca actgttaatt
    75481 catcagaaaa ccttgtaaga agttctaata ccatattcaa attcattcca gaaaataacc
    75541 taacattatg tagattagtt aatcttaaca ttgctgtaca tacacttgct ccatataagt
    75601 cagataaaat tatatattca cattctttat cttctgatat tgttttttct aattctaaag
    75661 caaaatctga agcactttgt ccagggtaca aaccatacga actgacacaa tctgctaaat
    75721 ctcctactat catttttact gcatttaaaa gcccttttga aaagtctcca tgagatgcta
    75781 atattatctt tttcatactc atcctcctac taaattatag attatatttc tgctgatact
    75841 gcatatttgt acttatcact tcttataaat tgctcattgt aatataagac atcattattt
    75901 tctgtataca ccgattgtct tactttcaat agtggcatat tacttgcaca tttaagatgg
    75961 tcagaatatt ctttgtttga atgttttact tcaaatatat tttctactcg tttaggtaat
    76021 gtgcttatat tattagatat aacctccatt aaagatttat cttctaattc ttcttttaat
    76081 aaaaacatgt aatctattct aaaatagtca acttcaaaaa taacaggtac ttcatctatt
    76141 aatctaagtc ttttaataca tattaccttc tcttctagtt caatacttaa agcttcagct
    76201 acttgcttat ctgctttttt tattaaaaca gagattattt tggtacttgg ttttgcatta
    76261 atacgatgac aagaattagt aaaactattt cctgcacatg ttgcttctat tctctctggt
    76321 attgttacat aagtcccttt accacgtttt ttacataata tatcttcttt tacaagttca
    76381 ttaagtgcat ttctcacagt tatacgactt atattaaatt ctttacataa gtctccttca
    76441 gatggaagtt tatctcctgg tttatatatg ccagatgcta tttgtttttt tatgttgtca
    76501 tatagttgtt gatataaagg aacaaaggaa tttacttcta aatccatttc ttttttttgt
    76561 ctcttttcat ccattttgct cacctcccta tgtaacattt ttataacatt atataacaag
    76621 ttctttatta catattataa caagatgaaa tcgttgtcaa ttttttttta aataattttt
    76681 aatttgacag tattttcttt tattttctct agtgtgacaa attgctattt ttacataaaa
    76741 ataagactgt tgtacaacag attaaattgt ttatacaaca gcctttattc acttattaca
    76801 tttatatttt tacttataaa tttatattaa aaaatgcctt atatccctta tacatttcat
    76861 atatgtctac tttagagaca atctcatgtg gtgcatgcat atttaaaact ccaacaccac
    76921 agtctataac ctctgcacct tgatttgcca atatatgggc tatagttccg cctcctcctt
    76981 ggtctacttt tccaagttca gcagtttgcc atattacatt tcctttatta aaaattctct
    77041 ttacttctga cataaattca gcattagcat cattacatcc actctttcct cttgaacctg
    77101 tatacttagt taaaactact ccatttccca tatatgccga atttctcttt tcatatgctt
    77161 ctccaaaatt tgggtcatat ccagcagaaa catcagctga taatacctta ctatttgcta
    77221 aagctcttct tactttaata tcacaataat ctccttctaa agcaatcagt tcagccacag
    77281 tattttcaaa aaactttgag tgcatacctg tattcccttt agaaccaatt tcttctttat
    77341 ctacacataa tgcaactgaa gtaaattctg gttgttcagt ttctagtata gcttttacag
    77401 cagcatatga acatacccta tcatcatgcc catatcccaa caccatagac ctatcaagcc
    77461 ctaaatctct agccttacca gctggaacta cttcaatttc agcacttaat aaatcttctt
    77521 caactatatt gtatttctca tttaaaatct ttaatatatt tgctgttata ggttcttttt
    77581 cttcatcttc taaaggcata tttccaatta atatatttaa agcttctcca ctaattcctt
    77641 ctgatagttt cttttgcatt tggtctccag ccaaatgaat caataaatca gttacacaaa
    77701 atactgggtc actatcttct tccccaatag atatgtccac ttttgttcca tcatttaata
    77761 taactatacc atgtaaagca agtggaatag ccgtccattg gtattttttt attccaccat
    77821 aataatgagt cttaaaaaaa cctagattac tctcttgata cagtggattt ggttttaaat
    77881 ctaatcttgg cgaatctata tggcttccta taatcttcat acctttttct atataatttt
    77941 tacctattac aaaaagtgct actgccttct ctttatttat aacataaatc ttatcaccac
    78001 aacttatgct tcctttttcc atagcttcat ctattgaaat atagttattt tctttagcca
    78061 attttataat ttcttttact gaaagtcttt cagtctttga cttacttaaa aactccatat
    78121 aattgctaga atattgcata atttgttcaa tagtattttc ttttctttca aaatcccaag
    78181 cattcttaaa ttcgtacttt aagttcatat tttcctccta ctaagttcta atttttattg
    78241 tttttcatgt attgctcata ttcttctggt gaaactactt tgacactatc tagtcttgat
    78301 ctaaagtggg ctctaaagtt ttctaaatat tctttcctta aaatttctct ttctttgatt
    78361 tcatcagcag aaaggattcc ctctttattt ttctttgcta attcattaat cctatctaat
    78421 ttcttcttgt caaacatttt ttcctcctaa aaaacctcta tttatttaat aaaataattt
    78481 attgcttttt atatctaact tgtttttata ttcacaaaaa aactcatcta tattatcact
    78541 tattatagat attccctttt ctagttcttc catgcttggg cgagctatat ttatcctaaa
    78601 gaatctatca tccactagat tgtcaaaaaa ataagtccct ggaagcattg acactccttt
    78661 gtttaacata aaatttgtaa atgcttgaga tgtatatcct cttggtaatt ctaaaaaaaa
    78721 gtttattcct ccacaagatt ttctaacttt taatttacca ctcaatttgt cattaatcaa
    78781 gttttttgcc aatttatact tatcagtata tatcttttct atatgactca aataattctt
    78841 ccaatcaaaa ttattcatat agtaatacat tgatttttga attaaacctg gtgttgatat
    78901 atctgatgaa tatttagccc ataaaacttt ttttaacaac tcatttggca tttctacaat
    78961 tcctatccta agacctggca taagtatttt tgaaaagctt tttatatata ctactctatt
    79021 tttatcatca taacttctaa ttgttctatt gtcctttgat tcaaaaacaa aatcacttat
    79081 aaaatcatct tctattatat aaaaatcatg ttcttctgcc aattctatca atttcttttt
    79141 tttatatgtt gagtaagata ttccagttgg attttgaaaa ttaggcataa tgtatataag
    79201 tcttggtttt attttttcca actttaattt taaaatacct atatcaattc catcatctaa
    79261 cataggtata gatattattt ttgcacctct acttttaaac acttcaattg ctccattgta
    79321 agaaggttct tccataaaaa caacatctga ataacttata agtcctttac aaactatatc
    79381 tataccttgt tgagcacctg atattatttg aatattttcc ttagtagttt ttatatttcc
    79441 atcacttaga tactctacca ttttttctct taattcttca gagccaagac cttcatcata
    79501 ttcaaatatt gaactaccat ctttagataa tgccatattt acagcatttt taaatgaatc
    79561 gataggaaac atatcattag atggattccc attgtcaaaa tgaattaaat cttctctttg
    79621 cacaataatc ttatttttcc tgttatctat accgctttta taagaattta aacttgatac
    79681 aaaagtacca ctccctataa ttttatatac atatccttca ttttctaaaa gctcgtatac
    79741 cttaactata gtagtgttat ttacttgtaa aaaatttgat agttttctta ttggaggcaa
    79801 tttttcatgt tctactaact ctttatttat tatcaattct tttatatgat taaatatctg
    79861 tatatattta gttgattttt tctcatttaa atctattctg tatttttcca aatttatcac
    79921 cgctcattgt atttatattt tattgatgct tttatgtata tttgatatta tttagtatgt
    79981 atatataata ccaaaatttt tataaaaagg ggaaatattt atgttttacg actatcacat
    80041 gcactcaagt ttctctacag acggaaaatc tacaatggaa gaaatggtaa aaaaatctat
    80101 tgaactcggt ttggaggaaa tttgtttcac agaccatgtt gactatgatg tatatgctga
    80161 tgattctttt tcaattgtct acgaagatta ttttaagagt ttagagactc ttcaaagcaa
    80221 atataaagat aaaatatcaa taaaaaaagg aattgaattt ggagttcaaa ctcaattaat
    80281 ggatacatac aaaaaggaag cacatcaata tccattggac tttataatat gttctatcca
    80341 tgctatagat acaatggact tataccttgg taattatttt aaagataaaa ctcaacatga
    80401 agtttatgaa aattactatc tttatttata taatattgtt aagaattata aagattactc
    80461 tgtcttaggt catttagatt tgattaaaag gtatgcacct tatgacacta ttttagatga
    80521 tagactattt tctgatataa ttgaagaaac tcttaaacaa gctatttatg atggcaaagg
    80581 tatcgagata aatacctctt gttatagata taatcttcca gacctaaccc catctaagta
    80641 tatacttcaa atgtataaag acttgggagg ggaaatcata accacaggtt cagattcaca
    80701 tcatataagt caagttgcat gtgagtttga ctacatatat tcattactaa aaaatatggg
    80761 atttaaatat gtatctaaat ttaataaatt gaaaccagaa tttataaaat tataaatttt
    80821 tacacctcct tgtgaatata tttaaaagat aaggaggtga tttttttgaa agtaccttat
    80881 ttagtactat caacagttat tttatttata tccaatttta ttgtaagaat atttggtttt
    80941 ttatataaaa tattcttatc aagagcacta ggtgaaacag gtttaggtat ctatcatatg
    81001 atttttaact ttttgatgat ttgcttagct gttacaacaa caggtatacc tactgcactt
    81061 agttgtctag ttgcaaagag aaaagcttta aacgatagac acaatactaa tgctttattt
    81121 atatcaactt tatatatatc atttttcgta gcactaatta tatctatagt tgcatctttc
    81181 aatagttctt ttttatcact taaattttta aaagatgcta aattaaatct atttatacta
    81241 gctgtttgtc ctgctatagt tataataact ctttcaaacg tactaagagg atattactat
    81301 ggcataaaga atgtaaaaat ccctgctatt ggacaaatca ttgaacaaat tggtaaaata
    81361 ttatttgttt ttttactagt tatgtacata aataataaat ctatgaattg ttatatagct
    81421 ctattaggta tatcaatcgg tgagttgagt aatattatat ttatgcttat ttgcttatgg
    81481 cgagattcat catttgacaa taggtatatt ataagcataa aagattttta taattcttct
    81541 atggaaacat taaaaatgtc tattcccata acttgtaata gaatgtcaaa catacttttg
    81601 caatctataa gttctatgat gataccatca agattagcat tatcaggaat gacttatcaa
    81661 caatctttaa gtatgtatgg tattgtcagt gggatggtaa tgccttttat atttttacct
    81721 tttactgttg gttcagcgct tattgtaaat ttaataccaa ctatttcaca agaaatggct
    81781 ctaagaaagc gtaagagtgt aattaaaaaa atcaaatact ccatacttct tactttattt
    81841 gtaggcatac tatcatcaat atttttttat ttctttggaa aagatttatg tatattagta
    81901 tttaaaaata cacttgcagg agaatatcta aaagctatgt ttttagttcc actatttatg
    81961 tccctaaatc aaactctatc tggcatttta cattcaataa gaaaagaatt agcttcaagt
    82021 ataaatacta ttactggcat gttaattcaa ctaatagctt tatatgtatt tcttccaatt
    82081 ccaggactta atatttatgc atacatatac acaatgacga tagtatcaat ctttacttgt
    82141 ctattacata ctatagtgct ttttaaatca ctaaaatcta tacgctagtt ataaaaacgt
    82201 gaaggctacc aatgtaaatt atacactttg gtagccttcc ttagatgatt tttatttata
    82261 atttaaactg tctatatatc ttacctatct atctgtggca acttggcttt ccacttccat
    82321 gattaggtcc acattgcgaa aaatcacata ctttagagaa agtatcaaca agtcttggtt
    82381 ggattggatt tggtgatgct aaaactacta tttgttcact tattaatgtg ctaactgttt
    82441 cttgtaagca aagtactaaa tctatatcat ttggtataat taattcatag aaaggttcac
    82501 aacattcgtt gcattctaat tttaatatag attttcctat acaatctaca gttaagttag
    82561 tttgatattc ttgtcttaaa gtaacagctc ttccgtcagc tggcaagcat attggtgctg
    82621 aaagtgtgtt aaaagtaaat tctacataat caactcttct cttacatcca cctcctgctc
    82681 taactgctgg gaaagctaat gcaacgaact ctgtacatcc acatctacct cttagctcta
    82741 gtactaaatt acgaactgct acagttaatc ctctttgttt ataagctact gatttgcctt
    82801 ttccttgtct acagcactca gcgtttcttt ctccacaaac tgcaaattca aaagttgttt
    82861 cacagtttct tcctactata tctcctaatg ggtctaaatc gaaatcttct aaagttgtca
    82921 ttcctgtgtc tataacgatt ccatcattac ttaagcatat tttttctata gttacacttg
    82981 cttgacctgc acttggaact gaaccaaata cttctactac ttctgtttca aaagttaatg
    83041 gctctccatt tggtcctgtt gcatctgtaa atgtttggaa ttgcatagta tcaaatattc
    83101 tattagcctc tattgcaaat ggcactgcat ttgatacaga gaagtttctt ggagatatag
    83161 gattacagca ttctggtcca catttgtttt caaaacattc atctgaatcc atttcacatg
    83221 gttcacaatc acatttacaa ttgtcatggc atccacaatt gtcatcacat ggattaggtt
    83281 tgcatggatt gcatgggtta ggtttacatg gattacatgg gttgcatgga ttgcaatcat
    83341 catggcactc acacttatta tcagtattac atccattatg atggtgtgat tttttaaaac
    83401 ctctcatgtc ttctgaattt atttcatctg tatacacttc ttcttcattc attgtagaca
    83461 ttggctgatt catcattctt cttttatttt ttttataatc ttgcattttt cattgccctc
    83521 cctgtaagcg attcttatta agtctttggc tttttgaagc ctaattaata ctatgctttt
    83581 ataatcttaa ttgttacttg ctttttgaat ttatcaataa ttaggcgtat ttagtagaaa
    83641 aatgcatatt aataaaaaaa gtactactat ttgaaatagt agcacttttt ttgtcccgaa
    83701 acaccggtgg ctaagtaaat tcacacccta ggcactccca ggtgggtgac ttgccagtaa
    83761 cctttaacgt ccaaactaac taggcatgtt ataatttacc agacacggtc tcccgtattt
    83821 catttgtagg ttgaatttaa aaaagcctta tcgtatgttt caggatttca tattattatt
    83881 atataataaa ttttgaattt tttaaagtgg ttttatatag taattgagat aatcttattc
    83941 tatcattact ttttcttcct tttttcttta tgtatttagt taattatcgt tttttcttag
    84001 ctctagtttt agtatttttt tcattataat tgtattcgga ttcttgctca ttaatgttgt
    84061 atagttcctc atcatatact atatcttcat cattttctat attttcatag cctgtgttct
    84121 tatcttctac taattcatct tcattatcct ccatttcacc ttcgtctgtt aactcatcat
    84181 aatcatcatc caattctttg tcttcacaat ctaattcttc gtcttcataa tttaactcat
    84241 cattattgtc ttcatcatca ttattactat catcacctct taaaagactt cctaacaatt
    84301 tgagattatt catactacca agattgttta tatttgccaa agagctcaaa ctaaatccac
    84361 cttcaccaaa gtcatctggt aaaaataatt ctgcaaataa atctatcttc tttttcattc
    84421 ctatagcttt ttcaactgaa ttttttcttt tttctgggaa tacatctata atttccttta
    84481 tcatcatatt ctttttatca tcactatcca tttttctgaa aaaatccgtt tcatcttctg
    84541 tatctaccat atctatatta tttaattttt ttattcctct aactaaatct aaaacacttt
    84601 ctatttttat tagtattttt ctttcatctc ttgacatgta ttttttagtt cttgttatta
    84661 tttccattcc catttctaaa tcttcttcac ttaaatccat gagccttaaa cctcttttta
    84721 tatcatttgc atcaaacctt aaattgccat gtgtagactg tgaaagttta tcatttgcat
    84781 tttttttgtt ttttctaact ctattatttc cttttgattt atttttatca tcaaatatag
    84841 agatattacc attactcaat gcaatcactc caatcaaaaa tagtaagtta ttcaagacaa
    84901 ttccccctta tattatataa ttgccctata ttaaagtatg tttttcatat tttaatgttc
    84961 catttttaaa gctcagtgca tatatattat ctataagaat ttttatttat attatatatc
    85021 actcacaatt caccacttca atattatttc tatatataaa tagtatgaat ataattcaat
    85081 atatatttat agaaaggggt ttttttatga aaaaattaga tacagagtca ttagaaaaaa
    85141 tggctaaaca aaaaaatatt gacaaggata aaatagaaaa gatggctgat agttacaaag
    85201 gaaaatcaga aaatgaactt atggaggaac ttataaaaat aggtaagaac ctagatggca
    85261 gagatgaagt agtatcaaaa ttcaaagcat ttttagatga aaatcaacgc aaaaaactgg
    85321 ataatataat ggaaaaaatc tcagatgcag aaaaccaaag agatactaaa ccagctaaaa
    85381 ctaagaaggc taaacctact aaaggtaagt caaattcacc tgcaccaaaa aatacaccag
    85441 gtagtcaaca aaaaaaatct aaaagtttat ttaagaaaac taaaaagtct aaccctcatg
    85501 aatagataaa aataaactat ttaagtaatt agataattat ttttagttaa tctattatta
    85561 aatttgatat tattgacata aaaaatcagg tagtgcctta ggcactacct gattgatttt
    85621 aatagtttta tttttttctt tctgtaacac tttctctatc aacaattcta taaggtaatt
    85681 ctattttctt attctcaatt aattccttat ttattaactt tataaccatt cttattgcta
    85741 ctgctcccat atcgtataga ggttgatata ctgtagtaag tttaggtcta tacattctag
    85801 ctatcttaac atcattaaat cctgcaacag atatgtcttc tggaacctta tatccagcat
    85861 cacatatagc atttatagca cctatggcag cctcatcacc tgttacaaaa gccgcatgag
    85921 gtattattcc atcatctaat agttctttca tactattgta tccactctca taatcagttc
    85981 caccatactt aatcaaactc ttgtctaatt ctatattgtt atttgaaagt gctttctcat
    86041 aaccagcaag tctttccatt tctaaaacag tatcatcttt actcgtcatt ataaaagcta
    86101 tcttttcatg acctttcttt ataagatgct ctgtcatatc aaaagtagct tcttcgttgc
    86161 tagtacttac tgtatatata tcataatttc tagcagtttt acttatatat gtcgctggta
    86221 ttccacaatt ttgtatatag ttgatatgtt cttgttcaac tatccatgaa atcataacta
    86281 taccttccac ttgttttgct ctcaatagat ttatactctt aagttcttgt tccttatcag
    86341 agtatgtatt cgctaaaaga atatcatagt catacatttt agcaacctct tctatcccat
    86401 ttaacacctc attaacaaaa gaatctgaaa cttctggaac tattacccct attaattgac
    86461 tcttctttgt tactaagctt ctagcaagtg gatttggtat atatccagtc tcttttataa
    86521 cctctaaaac tttttgtttg acttcatcag ttacaggttt tgaatcattt ataactctag
    86581 atacagtaga tattgacact cctgcttgtt tagcaacatc ttttatcgtt atattgcctt
    86641 tcatcttcat cctccttatt ttactaaatt tatctaaaac tgaaccaaat ttttgaaggt
    86701 tcctatttta actacattta tataagtttt tattttacca taaaagcaag tacatttaaa
    86761 tacattatat tttatattat accctatatt caacaaattt aataatattc attcttaatt
    86821 taaatcatat taaaaaataa aataaaaaaa tgctggtata aaataccagc atttttttat
    86881 tctaatgatt taagtattag cagccgcaac ctacttcacc atcaaagaat ccaccacatg
    86941 aacaagttat tagcaataat attaagaaag gtatccatga cattatgtca atgtctctcc
    87001 agcaatcttc aaaagctaag aataggaaga atagtactat tatccaccat cctcctccac
    87061 caaagcatcc ttcttctcca aaaaatctat ctaacataac aaagccctcc tttttttaat
    87121 aactgtgttc ttattctaag catccaccac agcagcaaag tattaataaa actattagga
    87181 atggtatcca tgccattatg tcaaattctg cccagctatc tccaaaagct aagaatagga
    87241 agaatagtac tattatccac catcctcctc caccaaaaca tccttcttct ccaaagaatc
    87301 tatctaacat tatacgttac ctcctgttga tattttgttg agcttttcgc tcctaacata
    87361 tactatgcat ttggtttcca ttttgctaat gtatttttac tattttttta aattttttaa
    87421 tttgaactaa aaaaggtaaa accataactt gtataagtta ctggttttac ctatttaata
    87481 atcaatattt tttagcaaca acaaccatca tcgaagttaa ataataacaa tactattaat
    87541 ataacccata tccatatatt gtcatcgcat aataagtctt ctaaaatgtc tgtgcataat
    87601 agtaagaata ctataactat tattatcaac attttattcc caaaaaatcc ttcgcatcct
    87661 ccaaagaaac gttccatatt gtcttctaat tttgtcataa ctaatcctcc ttgaatcatt
    87721 aagagactaa gttttgtctc tttaattaaa tatatgtagt aatagacaga taagttactt
    87781 ctaaaaagtt tttattgatt agtttattta tttctttttc accaagttta ttgtatctat
    87841 caacttcatc cagataatct tttttctcct ctgatatagt atagattaaa ctttctattg
    87901 attttatttt gtactcctta tatctttcta tcaagaagga tgtttttgaa ttttctattc
    87961 ctttctttac atgcattaac cttgatatgt agtcttcttt ttcattagat acataactct
    88021 ccttttcagc tacatcttca aggattaaat tggtctccat tacataatcc tctatacgtt
    88081 gcatatctaa agttattgaa ttataataaa aatttactgc tataagtaaa aacattccta
    88141 ctgaagttag taatagtcct acatatttca tagcatttcc tcctaagtta tatttgttat
    88201 caataaagtt tattcatcaa ataatacttt attactacat ttataaaatt ttattatttt
    88261 ttatagattc catattgaaa aattcttgat attatattaa actaacatta aaattaatta
    88321 aaactgcttt aggaggctta aaatgtttga gaaaataaaa gaaataatag cagaacaatt
    88381 aggggtagac aatttagatg agataactat ggaagcatct ttaatggacg acttagaagc
    88441 tgattcatta gatgctgttg aaattataat ggcccttgaa gatgaatttg gaatagaaat
    88501 accagacgag gaagctgaga actttaaatg tattggtgat atatgtaaat atatcgaaga
    88561 aaacaaatag tatcgttttg tctacaaata taaatagtct gtgtaaactt ctacataata
    88621 aattatatta gagttcgcac agactagatt acatttattt acaatatata aaatacacgc
    88681 tcttatattt aatttatata ctaagtatat aaattacttt tcttcataaa acgtaacatt
    88741 ctttattatt atatctatag ttccatcttg attttgtttt acagtatact tcattgggtc
    88801 ttcaaaatca gttagattcc cttttatgtc aaaaccatta tccgttttta tacttctttt
    88861 tttaagcttt ttctcaaccc attttttatc tatactaaaa ctttcgtcaa gacctttttc
    88921 ttccatatgc tctttaaagc tatcctttaa ctcatcatct ttaattgaat tatcaacaaa
    88981 gtcatttata tcaacttcat gtttttcctt cagtgtataa tttaatatac ttcttacatc
    89041 ttcagcttgc tttatatcat tactaagagc attggttatc caattttcag ctgtattttt
    89101 aaataccttg gtcttgtact tatcatcatc tattttttta gcatttaaaa attctgttac
    89161 aaacttagat tctgaccctt ctttttcagc atccttatct aaaagcctta gatgaaactc
    89221 atcatttata ccacttagac taatcaaagc tccttgcttt tgtcttaaag tctctgggat
    89281 accaatttca tttgaaacca tttgaatatt aaatttatca tccacaaatt caattgaatg
    89341 agtgtacaac tttttataat ctaatttcag tattgctaca ctcttttcat ctttaatagt
    89401 gtataaacaa attgccaaat cacaagattc tagtgcagca ttaattttca taacgtcaaa
    89461 caagtaagat gcaatttctt tagaattttt caaaaaagta ctttcatcat atattatttg
    89521 ttcacaacag tttttaatta aattgtcatt ataatcttta aaaacacctt ttcttaaatc
    89581 ctcatctttt gcaattcttt ttatagcttt ctggaaaaaa ccatccactt cttgattaac
    89641 tttgccttca aagtcattta atattggaac atcactattt ttgtccaaaa catgtattat
    89701 aaatttatgt attatcatat atatcacccc attatcttaa tttcgatatt aactctttca
    89761 tatcctctgg tatatctgct ttaaatttca atttttcttt tgttcttggt tgttcaaact
    89821 ctagcttata tgcatgaagt gcttgcctat ttattagctc ttcatctaca taaccataca
    89881 actcatcacc tattattcca tgacctatat gagccatatg tactcttatt tgatgtgttc
    89941 taccagtttc taagcttact tctaatacag ttgcattttc tagtctttct attactttat
    90001 agtgagtaac agatgactgt cctctttcat ctattatcct ctttattgaa tcttctgtag
    90061 gtctataaat tggctcatct atagttccct cattttcttt tataattcca tcaactactg
    90121 ttatatactt tttttcaact ttattttcac tcattgctgt agacaaagta tgatgtgcat
    90181 aagcattttt tgctactata actaaccctg aagtattcat atctaaccta tttacaaatc
    90241 ttatttttac gttttctttt tgattatcta tatagtaact aataccattt gctattgttt
    90301 tatcatagtg gctttttgtt gggtgaacta ccataaacgg aggtttattc accataatta
    90361 tatcaaaatc atcataaatt atctgtaaat ttaaatcttg aggttcaaaa tttgcttttt
    90421 cctcgtctat ttttacttct attaaatcac cactatacac ctttaaactc ggttttttat
    90481 atactccatt tactaaaaca ctcttttccc tcttcatttt tgataatgac ctaactgaga
    90541 aatttagctt gtccaataaa acttctttta aagtcatttc ttcttcattt gtatacgata
    90601 taagattata tctttgattc tcttttttaa acaaactttt acctactttc ttttatatct
    90661 tcctactttt tatatcttca aaatcatgat attatatatt ttacactatt tttgtttaat
    90721 agataataat tatttttaac tataaaaacc tgtaagaata acaaatagtt attcttacag
    90781 gttaaattca taattaaata tttaatttgt aaatattata atctaaaact atctcttaac
    90841 tattaaagta gttcccattc ctccacctat acaaagtgta gcaagaccag ttttagcatc
    90901 tcttctcttc atttcatata aaagtgtagt aagtattctt gctcctgagc atcctattgg
    90961 atgtcctata gctattgctc caccattaac attaacttta ttcatatcta tatttaagtc
    91021 tcttattaca gctacagatt gggcagcaaa tgcctcatta gcttcaacta aatctatatc
    91081 ttcaatagtc atattagcag cttctaaagc ttttttagtt gctggaactg gtccatatcc
    91141 cattatttta gggtcaacac cagctgttcc ataagaaact atagttgcaa gaggctctat
    91201 tcctagttct tcagcttttt ctttagccat tactactagc atagcagcac catcatttat
    91261 tcctgatgca ttaccagcag taactgttcc atctttttta aatgcaggtc ttaacttagc
    91321 aagtttctcc attgtagtgc caggcttaat atattcatct ttatctacta cagtgtcacc
    91381 ttttcttcct tttataacaa caggaactat ttcttcatca aattttcctt cagcttgagc
    91441 tttttcagct ttattttgac ttgcaagagc taattcatct tgttcttctc tagttatatt
    91501 ccattgctct gctatgtttt cagcagtaat acccatgtga tagttattaa atatgtctga
    91561 taatccatct tttatcattg aatcaacaaa agcagcatca cccattcttg caccatatct
    91621 cgcacttggt actaaataag gagacatact catgttttca gctccaccaa ctaacattat
    91681 atcagcatca cctaatgcta taagttgaga tgccattgaa acagatctta atccagaacc
    91741 acaaactata tttatagtca tagctggttt ttctactggt attcctgctc ctaatgctat
    91801 ttgtcttgct atattttgtc caagacctgc tgtaagtact ccccctaaaa gagattcatc
    91861 tatcatatct ggagttatgt tagctctttt tatagcttct ttagctgctg ttacccctaa
    91921 ctctaccgct gaaactgatt taaatgctcc tccaaaactt cctactgctg ttctagctgc
    91981 actggcaatt actacttctc tcatattcat tacccccatt aaattagatt tttcatatat
    92041 ccgaaattgt tttttaaaca attttattta aacttttaat tcccaaattc ttatttatta
    92101 taatcataga atcctatctt agtttttctt cctaattgat tagctctaac cattttagct
    92161 aaaagtggat gaggtctata tttagtatct ccaaattcag tatataaaac gttcattata
    92221 gctaaaacaa catctaatcc gattaaatca cctaatgcta gtggtcccat tggatggttt
    92281 gctcctaatt tcatagcttc atctatttct tctttacttg caacaccatc tgcatatata
    92341 ccaacagctt catttatcat aggtataagt attctattta ctacaaatcc aggagattca
    92401 gatacatcta ctggtacttt attgatactc ttagataatt caaatactgt atcaaaagta
    92461 acttttgatg ttaactgacc acttataact tcaactaatt tcatcatagg aactggatta
    92521 aagaaatgca ttcctataac tttatctggt ctcttagtag aagaagctat ttctgttata
    92581 gataatgatg aagtatttgt tgccaagata gtatcttctt tacataattc atctagtaac
    92641 ttgaaaacat ctttctttat attcatgtct tctacagatg cttctattat taaatccata
    92701 tcttttaaat cttcatagtt agtagttgaa ctaacatgac ttaatatttc tgcttttgta
    92761 gcttcatcca tttttccctt agtaactaac ttagttaaat ttttatctaa taaagctaaa
    92821 catttatcta tagcaccttg agttctactc tttaaacata catcatgtcc acaacttgca
    92881 aaagtttgta caataccact tcccatagtt ccactaccta ttacagctaa tttcatagtt
    92941 ataacctcct gttattttag tatttatatt ctgttaacta gattaaaata ctatttaatc
    93001 tagttaacag caaatatatt tttaattaga tttttaccct tttataaagt tagcttctct
    93061 cttttcaacg aaagctgaca ttccttcttt ttggtcttta gttgaaaaac aaagaccaaa
    93121 taaattagat tctatatcta ttccagtatt tatatcagtt tgagcaccaa gttgtattgc
    93181 ttctttagag tatctaactg caagctgagc atttttagct attatcttag ctaatttctc
    93241 aacttcttct attaaaatgt ctggctcaac gactctattt actagcccta ttttttcagc
    93301 ttcatcagct tttataactt gacctgtaaa gattaattct tttgcttttg ccattccaac
    93361 caatcttgta agtctttgag ttcctccata tcctggagtt attccaagag ttacttctgg
    93421 ctgaccaaat ttagctttag cagatgcaat tcttatatca catgccattg caagttcaca
    93481 tcctccacct aaagcaaatc cgtttacagc agctatcact acttttttac tattttctat
    93541 ttctccaaaa gcttttgctc ctaagatact aaaatcttta gcagctacag catctaaatc
    93601 tttcatgtat gcaatatctg ctccagctac aaatgccttt ccttcccctg tcaatattac
    93661 aacatcaata gtttcatcat tattaatatc tacaaatact tcataaagtt cttctaaagt
    93721 ctttgaattt attgcattaa gggctttagg tctattcatt ttcactgtac atatatttcc
    93781 atctacttca acagctacat tctcataaac tttaacatca cttgtactca taataccctc
    93841 cccaagaaat tagttagcta aaacttcacc tttttctttt gcaacactta actgactgat
    93901 aagttctgga agcactttat gaacatctcc aactatacca acatcagcat atttaaatat
    93961 tggagcttct ggatttttat ttatagcaac tataaactca gcatcttcca taccagctat
    94021 atgttgtatt gctccagata taccacatgc tatataaagg tctggtctta cagttttacc
    94081 agtttgacca acttgtcttg ctttatctaa ccaacctgca tctatagtgg cacgagaacc
    94141 agaaacttct ccacctataa tttcagctaa ttcataaagt atgtctaagt tttcttttcc
    94201 acccattcca cgtccagcag aaactaatat cttagcatct tctattttaa cttgtttttt
    94261 agcttctttt attacttgta caacttgaac taatttatca gcatcattaa attctacctt
    94321 gaaacggtta attacagctt ctttagtttc atcaggttca tttttcttca taacccctgg
    94381 tctaactgta gacatttgag gtctgaaatc tttacaaact attgttgcca ttatatttcc
    94441 accaaaggca ggtcttgtca ttaataataa ttttgtatct tcagctactg caagacctgt
    94501 acagtcagca gtaagacctg tatgtattct agcagaaact ctaggtgcta aatctctacc
    94561 tattgaagtt gcaccaaata atacaactat agggtcagct gcttttattg cttcataagc
    94621 tgcttttgta tatggttcag ttgtatacac tgctaaagct tcatcatcta ctactattac
    94681 ctcatctgca ccatagtgtg ctaatgtatc tattaaacct tctaccttac tacctaaaag
    94741 taatgcagaa acttttgtat cataatcttt tgctatttct gtagcctttc ctagtaattc
    94801 taaagaaaca gtttgaatta cattttctct ttgttctatt actactaaaa cgttacccat
    94861 tctttatccc cccttaaatt atatgatata cttctctttt aatttatcta tgataattcc
    94921 agctgatgtt ttcgcatctt cattgtatat tgtaccagct ggtttaactg attttgtaaa
    94981 tgatttaaat acactagttg gagaaccttt aagacctaaa ttagaagggt caacttctat
    95041 atcttttaca gtccatgttt ctactacatc attttcgaaa gcatcatata ttcttccaac
    95101 tttcatgtat cttggtgtgt tcatatcttt aagagttgtt ataaggcatg gcattttaac
    95161 ttttaagtca tggcaacaat cttcaaattg tctttttact aatacatatt caccttcagt
    95221 ttttatttct tcagcatatg ttattgatgg aagatttaaa tgttcagcta tttgaggtcc
    95281 aacttgtgca gtatctccat ctatcgcctg tcttccagct attataatat caaaatctat
    95341 attttttaat gctcctgcta atgctgatga agttgcccaa gtatcagcac ctgcaaatgc
    95401 tctatctgtt aataatatac ctctatctgc acccattgct aaagcttctt ttaaagccat
    95461 atctgcttga ggaggtccca ttgttataac agttacatga gcacccattt cttcttttaa
    95521 ttttatagct tcttctaaac ctgctttatc atcagggttt attatacttg gtactccatc
    95581 tctaattaaa gtacctgtat taggatctag tttaacttct gttgtatctg gaacttgttt
    95641 tatacaaacg actatattca taaatccttc ctccatatct attttaatat cgacctattg
    95701 tgtatatttt aatatttatc tattttaata attttcctga aataaccatt ctttgaactt
    95761 cactagttcc ttcatatatt tcagttatct tagcatctct catcattctt tctactggat
    95821 agtcacgagt gtatccatat cctccatgaa gttgtacagc ttttgtagta acttccatag
    95881 ctgtttcagc tgcaaataat tttgccattg ctgcttctac tccataaggt tttcctaagt
    95941 ctttatttat agctgcttga tatacaaggt gtctagccgc ttgtacctta acttccatat
    96001 cagctaattg gaattgtgta ttttggaatt ttgataatgg tctaccaaat tgtactcttt
    96061 cttttacata tttaacagtt tcatcaagag caccttgtgc taaacctaaa gcttgtgcag
    96121 ctataccaat tctaccacca tcaagagtag acattgctat cttaaatcct tgaccttctt
    96181 ttccaagtaa attttcttta ggtattctgc aatcctcaaa tattaattca ctcgtagctg
    96241 aacctcttat acccattttc ttttctttaa ctccaaagct aaacccagga gttccttttt
    96301 caactataaa tgctgatatt cctttgttcc ccttagattt atcagtcatt gccattacta
    96361 catatatgtc accagctatt gcatttgtta taaatatttt tgagccatta agtatgtatt
    96421 catccccgtc taaaacagca gttgtttgtt ggccagacgc atctgtacca gcattaggct
    96481 cagtaagacc aaatgctcct aatttttctc cacttgctaa tggtcttaag aatttttgtt
    96541 tttgttcttc attaccatat tgatatatag gccatgagcc aagagatgta tgagctgata
    96601 atataactcc tgtagtacca caaactctag acaattcttc aactgccatt atatatccta
    96661 cagtgtctcc accttctcca ccatattctt ttggatatgg tatacccatc attcctgctt
    96721 ttgccatttt ttccactgtt tcataaggaa atctttcttc ttcatcaagt tctgttgcta
    96781 aaggtttaac ttcattttca gcgaagctta catatagctc tttaagcatc tgatattttt
    96841 tagaatttaa atccataata gcctcctcag tattttataa atattttatt ttcatttatt
    96901 aattaaaatc tcggcaacat ctataataag gtatttgaat atacgtcgag aaatttataa
    96961 ccttaatcaa actacgctct atatttatat gtgattatac taaccaatta tgacattaat
    97021 ttaatcataa attgttaatt taaaatcaac tatacttaaa aaaaatctcg ctttttggaa
    97081 ttttgtgaaa tttcaagtta gaataagatt tctttcacac tggttagaga taaaataatt
    97141 tgtttacgat atttatatta aggtatatta aacattaaat attgtctgta catctgtttt
    97201 ttagccatgt acagaagatt tttatcgtat aaaaattatt ttaatagagc taaataatca
    97261 tatttttatc tgactatttt ttatttttaa atatcttaca tctataatag tatcactcaa
    97321 aggataattt ttcaataatt tctaattatt tttttaacaa tatttattac attttttcca
    97381 cttttttgtc atttttttat tgtttcgaaa aaaaatcaga attttttaac tttattttgg
    97441 attattagtt taaattagat tttcctctta gatttataaa tatttacaca aaaaaactac
    97501 ctctgtatag attgtataca gaggtagttt tttactaatt cctactatag tttactatat
    97561 ttttttacca attcttacaa acatctaccc atttttcaca cttagaaaac ttctccattt
    97621 cttcacatgt aagttctatt gcagagttac tactgccaca tgcaggaaat actgtatcaa
    97681 atcttttcat tgaatcatct aaatagactt ttatagaatt ttttaaacca aatggacaga
    97741 ctccaccaat agcatgtcca gtaaactcca agacttcttc tggtgtcaac attttagcct
    97801 tacaattaaa ttcagcctta tacttcttat tatcaatctt agcatcacca gctgtcacaa
    97861 ttaaaattgc atcatctcct attttaaatg agagtgtctt agctattctt gctggaataa
    97921 ccccagctgc ttcagctgca agttccacag tagcactaga ttgttcaaat tctaatatac
    97981 tgtcttcctt gccaaattgt ttaaaatact ctcttacatt acttattgac attaaatacc
    98041 cctcctagtc tgaactttta taaatttcat attattctta attatatcta taattgattt
    98101 atttttcaaa ttattccata atattagcat tccatgtatc attatttttt ccaactacta
    98161 gataaagtcc ttttgccatt ggaatattga caatatattc tcctttatac tctacactca
    98221 taccagattc attaaagtac ctataatcaa aatttagtcc ttttggaatt acaaaatcaa
    98281 cataaccttg attatttggt tttattccat atttcagagt tctttcagtt atagaatttt
    98341 tttcattaaa taaatctaca tttacatatg cagaacactt attcattccc tttttatttt
    98401 ccacacaatt ttcaaacttc attttagcac tgtttaattt ataactatat ttactattat
    98461 tgcttatttt aaatcttaca atagtaccaa catctctact tctcctgcta tcaaaatcaa
    98521 aaacaatttc ctctaaatga tttatttcat aatctttgac acttaccata tctctatata
    98581 ctaatttatt tatagctatg aatagtgtaa aaatccccaa aataaaaaat gaaactttta
    98641 taaacttctt catttttagt ctccttatat tttgtgctat tgtgctataa tattaatcaa
    98701 aattttaata attaaactta ttcttttttg aaatcttaat agaaaaatac attgatatta
    98761 taaaaattat tattgttaaa aatgtcatac tatataaatt tatatactta gtattagcta
    98821 tatcagttac ataatttgaa agatatactc ctccaacttt actataatta aaatgcttta
    98881 cttgatatac aatcatacta atcatcttca aaagacttcc atatacaaag taaattaaaa
    98941 tacttactat aaaaccacaa actttcattt ttccatatcc aaacttaaaa attaaaggca
    99001 gtaaaatcgt caaaattgct aaaaatatat ttacagaaaa aaatacatca tttaaaacca
    99061 tatttctaaa gaacactagt gatgtcaatt tacttagtaa ggacacaatt attgttacag
    99121 aaattattaa tcctacacct aataaatatt ttgagtaaac tatatcttct atactaactg
    99181 gcatactcct tataaaaatc cttgaatcat tttcataatc acactcaaat gtatttataa
    99241 atatcaaata actaacaaca atacttactg tataatatga aattgaatta aggaaaaaat
    99301 aaaacacaaa aaatagcaat atgtacttta aattacggat accatctgaa ctaatcccta
    99361 ttattaaatc ttttcttatt aaattgaaca tcatctcacc tcatttacat aataatacat
    99421 tagttcttct atagtaggat ttttgacctt atgcttatca atttctatca ataggctttt
    99481 tactttcaag ctatctccaa ctttaacaag tgcctcatta taatatttat actctttcac
    99541 accaactatg ctttctttaa ttgcttctaa ctctgcttta tttgccctaa ttatcttata
    99601 ttcttgttct attaattctt tcttaacagt aaaaatctga tttcctctat ttataaaaac
    99661 aagataatca gcaattttaa ttaaattatc agtattatga gtagaaatta ttacactact
    99721 acttccattt ttcacaaaat cttgtaagta ctgcattatt tcagttctta caattgggtc
    99781 tatcccagca gttggttcat ccaaaatcaa taacttagca ttgtgactaa gtgcacttga
    99841 taacataagc ttttcagatt gacctttaga taaattttca atatgcatat tttcttctat
    99901 atcaaactta ttaaggtatt catcaaacct ttctctatca aaattcttat aaaataaaga
    99961 aactattttt ctaaattcct taacctttaa atgcggataa aattgtaaag aatcatatac
   100021 aaaaccaata ttgtttttaa agcttattgg agaattttca atagtttcat tacaaagttc
   100081 aatttcacct tcatctgcat caataatccc cattataatt tttattaaag tcgtttttcc
   100141 cgaaccattt ggtcctataa tcccaacaat atccccttcc tttaactcta agtttatatt
   100201 atttaacttg aattttccta atttttttgt gatattcctt atgctaaaca catcttcacc
   100261 tcttatgcat ttttttatac ccacctatac atattttaac acattcacta caaaggtcat
   100321 ttataaattt ataaattaag aattataaaa ctatgttata atacaaagta tgaagaggtg
   100381 aatatatgaa aagaattata actataaata caaaccaatt aaataagtcc cttgagacta
   100441 aagaactctt aactagaaaa cttatcaatg ctggctttga agtgtattca gatatttatc
   100501 cagatacaga gcttattata tcaattggtg gtgatggctc ttttttaaga acagttagag
   100561 atttcgattt tcctgaaatt cccataatgg gaataaatac aggtcatctg gggttttttc
   100621 ctgatatttt accagataag attgatagct ttattgaagc ttatacaaaa aaagattata
   100681 ttattcaaga aatgtcactt cttaatgcgg aagtatatac aactactagt ggttctaata
   100741 tgcttgctgt aaatgaggtt gttataagag gagacaagtc taggactata cacctaaatt
   100801 taagccttga taataaacat atacaaaatt ttagtggaga tggtatgatt atttctactt
   100861 ccacaggttc aacagcctat aactattctg ctggaggtag tattgttgat ataaatcttg
   100921 aacttatgca gattacacct ttacatccga taaataccaa tgcatatagg tgctttacat
   100981 caagtataat atgttcaaat gaatctgtta taaagattgc accagaatat agatttgaag
   101041 attctgtatt gattgtcgtt gatggagttg agcacagatt tagacaaatc gaaaatataa
   101101 aagttagtat atctgatgca aaaataaaat tacttagaat gtcaaactat gagttttggc
   101161 atagagtatc tgaaaaattt ttatagactg tacttaggag gatttttaat atgaaaatag
   101221 gaataatgag tgatactcat ggtagcttac tttactttga aaaagcgtta aatgtattat
   101281 ctgattgtga tgttttatta catggtggag atgtcttata tcatggacct agaaatgata
   101341 ttccagaagg atataatcct aaaaaattta ttgagacatt aaataaatta gaaaacattg
   101401 tgattgtaaa agggaactgt gatgcagatg ttgaccagat ggttatagaa catcctattc
   101461 agagtcctta tgtcatgagc caatttggtg aaattagaat tatattgaat catggttata
   101521 tagaatcaga agaagaaatt attgacaaag caaagaaaat gggtggtgac atattagttt
   101581 taggacatac tcatgtaaaa aagctataca tggatgataa tttaatagta ataaatccag
   101641 gaagtacttc tatcccaaaa gatggaagcc attctgtcgc aattatagat atcataaaaa
   101701 ctgatgatga ggatgagctt gaacttgata taaacttaat tgacatcaat actggaaata
   101761 taataaatat caatgattag taaattttta ataaaaataa aataagcttt aatttattaa
   101821 actcataata aaaacaagta aaccatttta tttctatctc aattagaagt ttaagtacaa
   101881 taccttaaac ttctaattaa atagaatctg gtttacttgt tttattatat gctatattga
   101941 aatataactt agtttactta tttcattata tattatactg aaatataact tagtttactt
   102001 attttattat atattatatt gaaacatagc ttagtttact tattttatta tatatattga
   102061 agtgcaactt ggtttacttg ctattattat atattaattt tgatttacac aatattactg
   102121 taaggctaat gcttctgcat atggtttact atttttacct ccaccaactt gtacaaattt
   102181 atcagccttt acttttttta taaaactttt ctgtgcacta cttaaacttc cacttgcaag
   102241 tactacaggt gactttgttt ttgatgctaa tactccagca gcaagcccat caactaaatc
   102301 agcttctcta ccacttccat cttttgcaaa atacatatta ttaaccttac ttgattttcc
   102361 ataaaacttt tctaaaactt tcgcattagt atcttttcta tctgtccctg ctagtctttc
   102421 tgagtttact aactgtcctt caagtttttt acttatactg tactccccac ctactatgta
   102481 tgtcttagtt gagttttgtg taataaaatt ctttgcctca cttcttatgc tatccttacc
   102541 tgtatatatt atagctgtat tatcacttgc agctgggctt gatattgaag ttgcatctgc
   102601 cagtccatta tacccattaa ccactgccac ttttgagaca cctaaatcac cagtatcatc
   102661 tagctgtcta gtaagaagta aagatgtttc ttctctatct gctccaccga ttctactgac
   102721 taatacttcc atatcttcaa gagattcttt tacacttgat gaaatagctc cttcacttcc
   102781 aattaaaata acttctgctg gattaagcct ttttatttcc tctgttacat tatatggtat
   102841 actattttta tttgtaagca gtattggtgc atccaattta cttgccaaag gagttgaagc
   102901 caatgcatct ggcaatgaat ttgagttaac tagaaacacc ctttctgaac cattattcca
   102961 accactttga gatattttta tcgctgtatc aaatctatct tcaccaataa gtttttcctc
   103021 ctttggagat tttctacctt gaagataatt gttcatatct acctgtgcat tttgattttt
   103081 actaatagtg tctgcatata cacaacttgg caacataatc ccaagtgaaa gtgcaaatgc
   103141 tattattttt ttagatttaa ttttcaatac aattccccct tttaaatgtt aatacctatt
   103201 gatattcata ctttttattg ataccctaaa ctaaaaataa ttatctttta taaaaataat
   103261 tacaaaaata gctataccat tttaagtaca acacaagctt ataatcagct tgacttataa
   103321 agaatgatat agctattata actttaaatg cttaattttt aaatactttt taactaaact
   103381 ctttcagcat atttttcagc tattcttaca attagtttag tagctttctc catagaacta
   103441 actggtatac actcattttt cccatggaag tttaatccac cagtaaatat atttggacaa
   103501 ggtaatccat taaaagataa tcttgctcca tcagtaccac ctcttacagg aactaaacgt
   103561 ggttttatac ctaattcctc catagcttct ttagctatat caactataaa cataactggc
   103621 tcaatctttt ctttcatatt gtaataagag tcttttaaat ccaattccac tctattatcg
   103681 tatttcttat ttattttttc tatattctct atcataatag attttctatt ttcaaatttt
   103741 tctttacaat ggtctctaat aatataagcc atacttacat tctcgacatt tccacctata
   103801 gaatttaaat gccaaaatcc ttcatatcct tctgttgttt ctggtctttc atctgctggg
   103861 aacatttctg atatttcagc agctatatgt atagcattta ccattttatt tttagctgaa
   103921 cctggatgaa catttctacc atgtatagta atggttgcat ttgcagcatt aaaattttca
   103981 cattcaagtt ctccaactat tcctccatct aaagtatatg catattttgc tccaaatttt
   104041 tcaacatcaa ataaatcagc acctctacca atttcttcat ctggtgtaaa tcctattttt
   104101 atatctccat gcttaatttc tggatgattt attagatact ctattgcagt cactatctca
   104161 gctataccag ctttatcatc agacccaagt agagttgttc catcagtgac tattaaatcg
   104221 tcacctttaa attcttccaa ctctggagaa tcctttacat acgtaataac atttaacgct
   104281 tcatttaaaa ctatgtcttt tccatcataa ttttctatta ttcttggttt aatatctttt
   104341 ccactaacat cttcaattgt atctaaatgt gatatgaatc ctatagtatc cacaccatca
   104401 gtatttcctt ttaaagtagc cattatataa ctattttcat ctaaactcac atcatcaaca
   104461 cccattgttt ttagctcttc aactatatac ttagctaaaa ctctttgacc ttctgaagat
   104521 ggacagttct cacactgaga attagatgtt gtatcaaatg atacatattt taaaaatctt
   104581 tccactactt tttgtttcac gtatataccc tctttcttaa taagattaat atttttttat
   104641 ttacctgtga ataaaatttt atttttaaaa aatctatcaa ttattataat taaaaaatat
   104701 ccaccttctt aagtatatca tgcatacata ccaaacccaa acaaaaaatt actccaatta
   104761 ttccttttac ttggattcca ataaaaatcg ctgctagggt agctaatgga tttagtccaa
   104821 catttactga tactagttta ggttcaagta tttctctaat caaagacaaa acaaaaaata
   104881 tcacagtcat acttatagct ataaaataat tttttataag gaaataataa acaattactg
   104941 gaagatatat tgttattata cctaggaatg gaattaaatc cattaaagct cctacaaacc
   105001 ctactattag accgtatttc aatccaaata aagcaaaact tccccagatt gcaaaaaatg
   105061 ttatagccat aagtattgta taggccctta tatatccaac aagtgaaagc cctgcctctt
   105121 tctttacgtt ttttaccttc tttctaacat caacagtaaa catattataa aaactatttt
   105181 caatcttatc aaggtctttt gctataaagt acgtagcaat aaacaaggta attataaata
   105241 ttataatata tggaatagaa gtagccaatc caagtatact agtaagaaga ttttttgtaa
   105301 tttgcattac ttcaccactg aatttgttta ctaattgttc tacatcaaaa ttggctattt
   105361 cttgaaatga tttcataaag tcatttattt tatttaaaaa atacataata gtattactta
   105421 tatcctcagg attagcagat atattattta aaaatcccat taattctttc attgaattta
   105481 ttactattat tgtagtaact gtactgacta tagccactgc aagaaaactt agaacaagag
   105541 tagagatacc tttatttata cgaaacttat tttctaactt ttgtgatata ggattaatca
   105601 taagtgctat tatagcacct agaaaaaatg gagctatgta tggaaacgct ttgtaaataa
   105661 aaataaataa caatgtatat atacaaaaaa agatagtgtt gttttttaat ttgtataaaa
   105721 aattattttc tagtatgctc atcttaaaaa tctcctttct tctaatttat atttttattt
   105781 tgtccatttc atactagttt tatttgaata caaaataaaa ag
//
LOCUS       DAMJWC010000004       104648 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMJWC010000004 DAMJWC010000000
VERSION     DAMJWC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 104648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104648
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.004"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            39..155
                     /gene="rrf"
                     /locus_tag="PC503_000354"
     rRNA            39..155
                     /gene="rrf"
                     /locus_tag="PC503_000354"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            275..466
                     /locus_tag="PC503_000355"
     CDS             275..466
                     /locus_tag="PC503_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF2526375.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            621..2030
                     /locus_tag="PC503_000356"
     CDS             621..2030
                     /locus_tag="PC503_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2526376.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            2161..2850
                     /locus_tag="PC503_000357"
     CDS             2161..2850
                     /locus_tag="PC503_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF2526377.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2853..3788
                     /locus_tag="PC503_000358"
     CDS             2853..3788
                     /locus_tag="PC503_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF2526378.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3785..4678
                     /locus_tag="PC503_000359"
     CDS             3785..4678
                     /locus_tag="PC503_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF2526379.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4756..5502
                     /locus_tag="PC503_000360"
     CDS             4756..5502
                     /locus_tag="PC503_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF2526380.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5503..6336
                     /gene="rsmI"
                     /locus_tag="PC503_000361"
     CDS             5503..6336
                     /gene="rsmI"
                     /locus_tag="PC503_000361"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF2526381.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEIRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6359..7063
                     /locus_tag="PC503_000362"
     CDS             6359..7063
                     /locus_tag="PC503_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF2526382.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7251..7679)
                     /locus_tag="PC503_000363"
     CDS             complement(7251..7679)
                     /locus_tag="PC503_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2526383.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7716..9146)
                     /locus_tag="PC503_000364"
     CDS             complement(7716..9146)
                     /locus_tag="PC503_000364"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF2526384.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9278..9862
                     /locus_tag="PC503_000365"
     CDS             9278..9862
                     /locus_tag="PC503_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF2526385.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9878..10399
                     /locus_tag="PC503_000366"
     CDS             9878..10399
                     /locus_tag="PC503_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HDF2526386.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10465..10711
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10795..12732
                     /gene="metG"
                     /locus_tag="PC503_000367"
     CDS             10795..12732
                     /gene="metG"
                     /locus_tag="PC503_000367"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF2526387.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12762..13532
                     /locus_tag="PC503_000368"
     CDS             12762..13532
                     /locus_tag="PC503_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF2526388.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13870..14301
                     /gene="phnG"
                     /locus_tag="PC503_000369"
     CDS             13870..14301
                     /gene="phnG"
                     /locus_tag="PC503_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF2526389.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14316..14891
                     /gene="phnH"
                     /locus_tag="PC503_000370"
     CDS             14316..14891
                     /gene="phnH"
                     /locus_tag="PC503_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF2526390.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTNLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14894..16009
                     /locus_tag="PC503_000371"
     CDS             14894..16009
                     /locus_tag="PC503_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF2526391.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRAAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKIKHPIYEDEEITIGDMLVTECEIVSKASQNK
                     TENSKNNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIKKFEEVSLGDI"
     gene            15999..16868
                     /locus_tag="PC503_000372"
     CDS             15999..16868
                     /locus_tag="PC503_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF2526392.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16861..17727
                     /locus_tag="PC503_000373"
     CDS             16861..17727
                     /locus_tag="PC503_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526393.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQREFKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17768..18481
                     /locus_tag="PC503_000374"
     CDS             17768..18481
                     /locus_tag="PC503_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2526394.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18482..19651
                     /locus_tag="PC503_000375"
     CDS             18482..19651
                     /locus_tag="PC503_000375"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF2526395.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19655..20491
                     /locus_tag="PC503_000376"
     CDS             19655..20491
                     /locus_tag="PC503_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2526396.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20492..21487
                     /locus_tag="PC503_000377"
     CDS             20492..21487
                     /locus_tag="PC503_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2526397.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21505..23193
                     /locus_tag="PC503_000378"
     CDS             21505..23193
                     /locus_tag="PC503_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2526398.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     EFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23205..24272
                     /locus_tag="PC503_000379"
     CDS             23205..24272
                     /locus_tag="PC503_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2526399.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            25036..26103
                     /locus_tag="PC503_000380"
     CDS             25036..26103
                     /locus_tag="PC503_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2526400.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26295..26825
                     /gene="rnmV"
                     /locus_tag="PC503_000381"
     CDS             26295..26825
                     /gene="rnmV"
                     /locus_tag="PC503_000381"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF2526401.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26996..27865
                     /gene="rsmA"
                     /locus_tag="PC503_000382"
     CDS             26996..27865
                     /gene="rsmA"
                     /locus_tag="PC503_000382"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF2526402.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27931..29193
                     /locus_tag="PC503_000383"
     CDS             27931..29193
                     /locus_tag="PC503_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526403.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29344..30459
                     /locus_tag="PC503_000384"
     CDS             29344..30459
                     /locus_tag="PC503_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2526404.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30645..31541
                     /locus_tag="PC503_000385"
     CDS             30645..31541
                     /locus_tag="PC503_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2526405.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31611..32408
                     /locus_tag="PC503_000386"
     CDS             31611..32408
                     /locus_tag="PC503_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526406.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32463..33815)
                     /locus_tag="PC503_000387"
     CDS             complement(32463..33815)
                     /locus_tag="PC503_000387"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF2526407.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            34034..34912
                     /gene="purR"
                     /locus_tag="PC503_000388"
     CDS             34034..34912
                     /gene="purR"
                     /locus_tag="PC503_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF2526408.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            35068..35346
                     /gene="spoVG"
                     /locus_tag="PC503_000389"
     CDS             35068..35346
                     /gene="spoVG"
                     /locus_tag="PC503_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF2526409.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35559..36938
                     /gene="glmU"
                     /locus_tag="PC503_000390"
     CDS             35559..36938
                     /gene="glmU"
                     /locus_tag="PC503_000390"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF2526410.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            37033..37983
                     /locus_tag="PC503_000391"
     CDS             37033..37983
                     /locus_tag="PC503_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF2526411.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38821..38906
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            39068..39589
                     /locus_tag="PC503_000392"
     CDS             39068..39589
                     /locus_tag="PC503_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2526412.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTSATTNSLGNPLTSNTKIDNNVLY
                     IVLIDNTVMDTTK"
     gene            39740..41416
                     /locus_tag="PC503_000393"
     CDS             39740..41416
                     /locus_tag="PC503_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2526413.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41428..42636
                     /locus_tag="PC503_000394"
     CDS             41428..42636
                     /locus_tag="PC503_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2526414.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42651..44363
                     /locus_tag="PC503_000395"
     CDS             42651..44363
                     /locus_tag="PC503_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF2526415.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44356..45264
                     /gene="pilO"
                     /locus_tag="PC503_000396"
     CDS             44356..45264
                     /gene="pilO"
                     /locus_tag="PC503_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF2526416.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45291..45857
                     /locus_tag="PC503_000397"
     CDS             45291..45857
                     /locus_tag="PC503_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2526417.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45894..46421
                     /locus_tag="PC503_000398"
     CDS             45894..46421
                     /locus_tag="PC503_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2526418.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46442..47980
                     /locus_tag="PC503_000399"
     CDS             46442..47980
                     /locus_tag="PC503_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526419.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            48080..49162
                     /locus_tag="PC503_000400"
     CDS             48080..49162
                     /locus_tag="PC503_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF2526420.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            49143..49925
                     /locus_tag="PC503_000401"
     CDS             49143..49925
                     /locus_tag="PC503_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2526421.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            50027..50677
                     /locus_tag="PC503_000402"
     CDS             50027..50677
                     /locus_tag="PC503_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2526422.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50691..51251
                     /locus_tag="PC503_000403"
     CDS             50691..51251
                     /locus_tag="PC503_000403"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF2526423.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51268..54654
                     /gene="mfd"
                     /locus_tag="PC503_000404"
     CDS             51268..54654
                     /gene="mfd"
                     /locus_tag="PC503_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF2526424.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54685..55680
                     /locus_tag="PC503_000405"
     CDS             54685..55680
                     /locus_tag="PC503_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2526425.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55804..56343
                     /gene="spoVT"
                     /locus_tag="PC503_000406"
     CDS             55804..56343
                     /gene="spoVT"
                     /locus_tag="PC503_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF2526426.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56463..58076
                     /locus_tag="PC503_000407"
     CDS             56463..58076
                     /locus_tag="PC503_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2526427.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58183..59631
                     /gene="mazG"
                     /locus_tag="PC503_000408"
     CDS             58183..59631
                     /gene="mazG"
                     /locus_tag="PC503_000408"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF2526428.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59720..59998
                     /locus_tag="PC503_000409"
     CDS             59720..59998
                     /locus_tag="PC503_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF2526429.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            60070..60312
                     /locus_tag="PC503_000410"
     CDS             60070..60312
                     /locus_tag="PC503_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF2526430.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60374..60628
                     /locus_tag="PC503_000411"
     CDS             60374..60628
                     /locus_tag="PC503_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF2526431.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60629..61162
                     /locus_tag="PC503_000412"
     CDS             60629..61162
                     /locus_tag="PC503_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526432.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61168..61452
                     /locus_tag="PC503_000413"
     CDS             61168..61452
                     /locus_tag="PC503_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF2526433.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61565..62485
                     /locus_tag="PC503_000414"
     CDS             61565..62485
                     /locus_tag="PC503_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF2526434.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDKGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62575..64947
                     /gene="spoIIE"
                     /locus_tag="PC503_000415"
     CDS             62575..64947
                     /gene="spoIIE"
                     /locus_tag="PC503_000415"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF2526435.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65298..67190
                     /gene="pepF"
                     /locus_tag="PC503_000416"
     CDS             65298..67190
                     /gene="pepF"
                     /locus_tag="PC503_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2526436.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67304..68269
                     /gene="galU"
                     /locus_tag="PC503_000417"
     CDS             67304..68269
                     /gene="galU"
                     /locus_tag="PC503_000417"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2526437.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68769..70373
                     /gene="rho"
                     /locus_tag="PC503_000418"
     CDS             68769..70373
                     /gene="rho"
                     /locus_tag="PC503_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF2526438.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70526..70726
                     /gene="rpmE"
                     /locus_tag="PC503_000419"
     CDS             70526..70726
                     /gene="rpmE"
                     /locus_tag="PC503_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF2526439.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70871..71764
                     /locus_tag="PC503_000420"
     CDS             70871..71764
                     /locus_tag="PC503_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF2526440.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71782..72630
                     /gene="prmC"
                     /locus_tag="PC503_000421"
     CDS             71782..72630
                     /gene="prmC"
                     /locus_tag="PC503_000421"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF2526441.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72674..73738
                     /gene="prfA"
                     /locus_tag="PC503_000422"
     CDS             72674..73738
                     /gene="prfA"
                     /locus_tag="PC503_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF2526442.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73867..74547
                     /locus_tag="PC503_000423"
     CDS             73867..74547
                     /locus_tag="PC503_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF2526443.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74576..75616
                     /locus_tag="PC503_000424"
     CDS             74576..75616
                     /locus_tag="PC503_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF2526444.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75633..76082
                     /locus_tag="PC503_000425"
     CDS             75633..76082
                     /locus_tag="PC503_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF2526445.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            76099..76551
                     /gene="rpiB"
                     /locus_tag="PC503_000426"
     CDS             76099..76551
                     /gene="rpiB"
                     /locus_tag="PC503_000426"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2526446.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76587..77216
                     /gene="upp"
                     /locus_tag="PC503_000427"
     CDS             76587..77216
                     /gene="upp"
                     /locus_tag="PC503_000427"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF2526447.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77511..78326
                     /locus_tag="PC503_000428"
     CDS             77511..78326
                     /locus_tag="PC503_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF2526448.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78552..78989
                     /locus_tag="PC503_000429"
     CDS             78552..78989
                     /locus_tag="PC503_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2526449.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79174..79401
                     /locus_tag="PC503_000430"
     CDS             79174..79401
                     /locus_tag="PC503_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF2526450.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79406..79792
                     /locus_tag="PC503_000431"
     CDS             79406..79792
                     /locus_tag="PC503_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF2526451.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79795..80499
                     /gene="atpB"
                     /locus_tag="PC503_000432"
     CDS             79795..80499
                     /gene="atpB"
                     /locus_tag="PC503_000432"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF2526452.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80568..80828
                     /gene="atpE"
                     /locus_tag="PC503_000433"
     CDS             80568..80828
                     /gene="atpE"
                     /locus_tag="PC503_000433"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF2526453.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80951..81448
                     /gene="atpF"
                     /locus_tag="PC503_000434"
     CDS             80951..81448
                     /gene="atpF"
                     /locus_tag="PC503_000434"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF2526454.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81445..81990
                     /locus_tag="PC503_000435"
     CDS             81445..81990
                     /locus_tag="PC503_000435"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF2526455.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            82007..83509
                     /locus_tag="PC503_000436"
     CDS             82007..83509
                     /locus_tag="PC503_000436"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF2526456.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83537..84415
                     /gene="atpG"
                     /locus_tag="PC503_000437"
     CDS             83537..84415
                     /gene="atpG"
                     /locus_tag="PC503_000437"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF2526457.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84428..85822
                     /gene="atpD"
                     /locus_tag="PC503_000438"
     CDS             84428..85822
                     /gene="atpD"
                     /locus_tag="PC503_000438"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF2526458.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85825..86085
                     /gene="atpC"
                     /locus_tag="PC503_000439"
     CDS             85825..86085
                     /gene="atpC"
                     /locus_tag="PC503_000439"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF2526459.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86547..86927
                     /locus_tag="PC503_000440"
     CDS             86547..86927
                     /locus_tag="PC503_000440"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF2526460.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86942..87403
                     /locus_tag="PC503_000441"
     CDS             86942..87403
                     /locus_tag="PC503_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2526461.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87424..88014
                     /locus_tag="PC503_000442"
     CDS             87424..88014
                     /locus_tag="PC503_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526462.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQDDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            88029..89186
                     /gene="alr"
                     /locus_tag="PC503_000443"
     CDS             88029..89186
                     /gene="alr"
                     /locus_tag="PC503_000443"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2526463.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEKSVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89219..89506
                     /locus_tag="PC503_000444"
     CDS             89219..89506
                     /locus_tag="PC503_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF2526464.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89475..89858
                     /locus_tag="PC503_000445"
     CDS             89475..89858
                     /locus_tag="PC503_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2526465.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            90029..90856
                     /locus_tag="PC503_000446"
     CDS             90029..90856
                     /locus_tag="PC503_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2526466.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90849..91790
                     /locus_tag="PC503_000447"
     CDS             90849..91790
                     /locus_tag="PC503_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2526467.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEVIIAKRM"
     gene            92213..93307
                     /locus_tag="PC503_000448"
     CDS             92213..93307
                     /locus_tag="PC503_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526468.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93533..93949
                     /locus_tag="PC503_000449"
     CDS             93533..93949
                     /locus_tag="PC503_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526469.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(94131..94700)
                     /locus_tag="PC503_000450"
     CDS             complement(94131..94700)
                     /locus_tag="PC503_000450"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF2526470.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            94854..96011
                     /locus_tag="PC503_000451"
     CDS             94854..96011
                     /locus_tag="PC503_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF2526471.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96615..97085
                     /locus_tag="PC503_000452"
     CDS             96615..97085
                     /locus_tag="PC503_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2526472.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIY"
     gene            complement(97794..98948)
                     /gene="nagA"
                     /locus_tag="PC503_000453"
     CDS             complement(97794..98948)
                     /gene="nagA"
                     /locus_tag="PC503_000453"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2526473.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(99031..99756)
                     /locus_tag="PC503_000454"
     CDS             complement(99031..99756)
                     /locus_tag="PC503_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2526474.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            100025..100954
                     /gene="pfkB"
                     /locus_tag="PC503_000455"
     CDS             100025..100954
                     /gene="pfkB"
                     /locus_tag="PC503_000455"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2526475.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(101083..102000)
                     /locus_tag="PC503_000456"
     CDS             complement(101083..102000)
                     /locus_tag="PC503_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2526476.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            102471..103640
                     /locus_tag="PC503_000457"
     CDS             102471..103640
                     /locus_tag="PC503_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2526477.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            103689..104540
                     /locus_tag="PC503_000458"
     CDS             103689..104540
                     /locus_tag="PC503_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2526478.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
BASE COUNT        41813 a        11415 c        18900 g        32520 t
ORIGIN      
        1 tattaaaaac ttaatagaaa tattaagcat aaagattatg tggttacaat agcagagagg
       61 atacacctgt tcccattccg aacacagaag ttaagctctc tagcgctgat ggtacttggt
      121 gggaaactgc ctgggagagt aggacgtagc cacgtaattt tttttatttt ttgtcaaaaa
      181 aaacaaaaaa tacgtatttc ttttttcatt tcgggaaaac taaacacagg aattatggac
      241 tttataaaaa tttaattctt gaggagtgat ataagtgaaa aaagttgctt taattttagc
      301 tataataggt gcgcttaact ggggtgcaat tggtattcta ggtacagact taataggtag
      361 tatctttggt ggaacatatg aaatggtaag tagaataata tacttcattg taggtttagc
      421 tggattatac ttaataccaa gtttaatgtc tgatgataga gaataattta tgcttttatg
      481 ttaaatacct cattctaaat gtttagaatg aggtatttaa ttttataaaa atattaattt
      541 gtttcttttt taatggtaaa atagataaga attgaagttt taaaaagaag tattatgtaa
      601 aaaaggagta ctattaatat atgtttatta ttaatgaatt aaataagatt gtaaatgaag
      661 aagtaatatc ttttcatatg cctggtcata aaaagggaca ggtttataaa aagttaggat
      721 ataaagatat actaaaaaat ttgtataaaa tggatacaac tgagatatta ggaacagata
      781 atttacactt tccggaagga attataaaaa attcacaaaa aaaagcatca agagtattta
      841 aaagtgatta tacttgctat ttagtaaatg gtagtagctg tggaatacaa tctgcaataa
      901 tgtcagtatg tagtcctaaa agtaaaataa taacaaatag agactgtcat cagtctgtta
      961 taaatggatg tattttagga gatatagata tagagtatgt gccttgtgag ataagtgaag
     1021 agacaaatgt cttaaaaggg atatctataa gtaatgtgat tgatataata gataaaaact
     1081 tggatgcaaa agcagtactg cttacttatc ctacatatta tggaatgaca tatgatttag
     1141 aatacatatg taattatgca catagcaaaa agatggtagt gatagtagat gaagcacatg
     1201 gtgcgcattt agggcttagc gagaggcttc ctaaaacagc tcttgagcaa ggcgcagata
     1261 tagttgtaca gagtacacat aaaactcttc cagcatttac acaatcgtca atgatacata
     1321 tacagggaga ccgagttgat atagataaaa tattgaacat gttaagaatt acagaatctt
     1381 caagcccttc atatttatta ttatcttctc tggaattagc agtagatata tatgaaaata
     1441 aaggaaaaga attaatggaa gagcttttaa ataatattat aactttcaaa aataaagttg
     1501 attcaaatat taatatatac gacacaaatg ataaaacaaa aatatttata tcatctaaaa
     1561 atatgggttt aacaggttat gaactagaaa atattttaag aaacaaatat aacatacaag
     1621 tggagttatc taattattat ggagttcttt taatatgtac aataggaaat actgttgagg
     1681 atttctctag tttagaaaca gcattaaaca atattgtaaa ggaagacttt aaatttgaaa
     1741 agttagaaaa taaaaaatac cctgttgtta ttccaaagaa aatattaaca cctagagaag
     1801 cattttataa aactaaaaaa agtgttaaaa tatatgacag cataggtaaa gtttgtggtg
     1861 aatgtatagt tccataccca cctggaataa gtgtaatatc tcctggtgaa gtaataagta
     1921 aagaaataat agactatcta atgttttgtc attctaaagg catgattgtg agtggattga
     1981 aagatgtaga tttaaatttt atacaaataa tagatttaga agacatttaa aaattatgat
     2041 ataaaagtag atagaagtag atagtttaaa attgtgaaga gaaataaata gactgcttat
     2101 atagagctat ctaataaaaa tactaaaaaa gtaaaaagtg tttgtatgga ggatatgaaa
     2161 atgaaaggta agttaataat tatagagagt ggttcagatg caagtggaaa ggctactcag
     2221 acagaaatat tatatgaaag attaaaaaaa gaaggctata tgattaaaaa ggtagaatat
     2281 ccaaattatg aatctccatc atctgccttg gtgaaaatgt acctaaaagg agactttggt
     2341 aaaaatgcat cagatgtaga cccatatata gcatcaactt tttttacagc tgataggtat
     2401 gcatcattta aaaccgattg ggaggagttt tacaatgaag gtggaataat tatcgcagat
     2461 agatatacaa cctctaatat ggtacatcag gcctctaaaa tggatatttg tgatagagaa
     2521 gagtatttaa attggttagc tgattatgaa tttaatttat ttaagatacc acaacctgat
     2581 tgtgttatat ttttagatgt gcctattgaa tttagtaaaa agcttatgga gaatagaaaa
     2641 aataaaatta caggggaaga aaaaaaggat attcatgaaa gtgacataga gtatttagag
     2701 aaatcttaca acaatgcttt atatatagca gataaatatg attggaaaaa aataaattgt
     2761 gttttagata acaaattaag aagtattgaa agtatacata atgaaattta taaaatagtt
     2821 cttgattcaa taaaacctat ggagagataa atatgtattt tgaaaatatt atagggcaag
     2881 attttgcaaa gaaatattta acaaattcta taaagaaaaa taaacttaat aatgcgtata
     2941 tgtttgaagg aatggatgga ataggaaaaa agaaatttgc agatgaatta tcaaaactat
     3001 tacttgatta tgaaaatctc gaaaatagtc cagactatgt actcataaaa ccagatggaa
     3061 atagtataaa aatagctcaa atcagaaatt tacaatcaga tatagtaata agacctcata
     3121 aagactataa aatatatata atcaataatg ctgaaaaaat gactgtggaa gctcaaaatg
     3181 cacttttaaa gacgctagag gaacctccaa actatgctat aataatctta gtcacaaaca
     3241 acaaggaatc tttattagaa actataaaat ctagatgtga tataataaag ttctcaccta
     3301 taccaattga agacttaaaa cgttatttga taaatacagg tatagaagaa gaaagagctc
     3361 aattattggc tattttttcg agaggaagta ttgagaatgc tctaaatcta tctcagtctt
     3421 ctgagttttc aatgatgaga gaagatatac aacagtatat tcagataatg ttagataaaa
     3481 acatagtgga gattttaaat ataccaaata atatggaaaa atatagaggt aagattatag
     3541 ctttattaga tatgatgata aactattttc gagatatcat cctattaaaa gaaaatgtaa
     3601 acaagaacat gttaataaat gtagataagc tagttttcat tcaaaatatg agtggaaaaa
     3661 ttagttattc tcaattgtcc aagattattg atataataga agatgcaaag agtaaaataa
     3721 aaagcaattg caatttcaat ataagcatac aagttatgtc tttaaatata tacgaggtga
     3781 ttaaatgata aagatagtag gtataaggtt taaaagtgct gggaaaatat attattttga
     3841 ccctgttgat tttaatatag agcaagatat ggatgtagtt gtagaaactg caagaggctt
     3901 ggagtatggg aaagtagtcg ttggtccaaa agatatggat gaaagcgaat tagtttctcc
     3961 tttgaagcca attataagaa tagctacaga agaagataaa aaagtatatc tagaaaataa
     4021 ggaaaaggca aaagaaactt ttgagttgtg ccaacaaaaa ataaaagaac atgagttaac
     4081 aatgttttta atagattgtg agtatacatt tgataggaat aagttgattt tttactttac
     4141 agcagaagga agaatagatt ttagagaatt ggtaaaagac ttagctgcta tatttaaaac
     4201 tagaatagaa cttagacaaa taggtgtcag agatgaagct aaatctatag gaggtctagg
     4261 gccttgtggt agaaaacttt gttgttcatc ttggttaggt gattttcaac cagtttcaat
     4321 aaaaatggca aaagaccaaa gtctatctct aaatccaaca aaaatatctg gaatatgtgg
     4381 gagattattc tgttgcttaa aatatgagca tgatgtatat agtgaagcaa tagaaaaaat
     4441 gcctgttgta ggtgcattgg tgcaatcaga tgatggaaaa ggaaaagttg tagaagtgaa
     4501 tcctttatta gaacaaatta aagtggaatt tcaagacaag acagtaaaga tatacacaag
     4561 agaagatata aaaatactta gagagcctaa aaaatgtgat ggctgtggtg gtaaatgtaa
     4621 ggataatgat ggattagatg aagccacact aagagagcta aagaaattag aagattaaat
     4681 ttaaggtagg gcttttccta ccttttttaa agcaattaat gcttaaagtt attaatattt
     4741 gaggagaatt tatatatgca attaaaagat tcagaaagaa tagatgattt acaattaaaa
     4801 ggccttaaaa ttatacaaga tactaatggt ttttgttttg gtatagatgc agttttatta
     4861 gccaatttta ctaaaataaa aaaagatgcc aaagtagtag atttgggtac tggaactgga
     4921 attataccta ttttgatagc tggaaaaagt gaagctaaaa aaattattgg cgtggaaata
     4981 caagaagatg tatatgaaat ggcaactcgt tctataaaat taaatggatt agaagaaaga
     5041 gttgagatta taaatgaaga tataaaatac atagacaaag tcttagacat aaatggttac
     5101 catgtagtca catcaaatcc tccatatatg catattgatg gaataaaaaa tccaaatgat
     5161 aaaaaagcaa tatcaagaca tgaagtaagg tgcaatttgg aagatgtaat tagagctgca
     5221 tccagattgg ttatgcctag aggaaaattc ttcatgatac atagaccaac aagattggtt
     5281 gatataataa ctttagggag aaaatataaa ttagaaccaa aggttattca atttgtgcat
     5341 ccaagacctc aaaaagcacc gaacttagtt ttggttcaat ttgtaaaaga tggaaggcca
     5401 gagcttaaaa tattggaccc attgtatgtt tatggagaag atgggaatta tacaaaagaa
     5461 ttaaaagcaa tatataataa taaagatata ggagagttgt aaatgagtgg gaaattgtac
     5521 atatgtccaa caccaatagg aaacctagaa gatataacat atagaacttt aagaacatta
     5581 aaagaagtag acttgattgc agcagaagat acaagacata gtataaaact tttaaatcat
     5641 tttgaaatct caaaaccact aactagttat catgaacata ataaggattc aaagggagat
     5701 tatttgataa ataaactaat tgatggtgaa aatatagctc tgataagtga tgcaggtatg
     5761 cctggtatat ctgacccagg agaagagata ataaaacaag ctatacaaaa taacatagag
     5821 atagaagtat tgccaggtgc aacagccttt gtaacggctt tagttggctc tggtatggac
     5881 acacatagat ttgtttttga gggcttttta gatagagata aaaaagttag gaaagcacaa
     5941 ttggaagaat taaaggaaga aagtagaact ataattttct atgaatcacc acatagattg
     6001 aaggatacac taaaagatat gcttaaaatt cttggtaata ggaatatttc tataaataga
     6061 gaacttacaa aaaaatatca agaaataata agagaaaata tagaaactac cataaaaata
     6121 tttgaggaaa aagaaataag aggagaattt gtattaatag tagagggttt tcatggtgag
     6181 aagtcaaaga aagaaaatta tgatgggctt acagataggg aatatgtttt aaaactaatt
     6241 gaaagtggta tgaacaaaaa agatgcaata aaaatagttt gtaaagatag aaagttaaag
     6301 aaagatgtgg tttataaaca agttttagat ttataaaacc tgaatctgag gtgattttat
     6361 ggaaataggg aaaattataa tagagagttt aaagagggaa gatacacata aaatatttat
     6421 agaattagat aataagcatg aattagaaaa aataattcct aaaataagct gtatgaagtc
     6481 tgtaggtgaa tgtaaatatc atgtagtaaa ttgttttgaa cattctataa acgcattaaa
     6541 agaattagaa atagtattaa atgataagga tttttttcca atacatctaa gaaaacatgt
     6601 gtcaaactat ttaaacacat atattgaaga aggaataaat aagttacatg tattaaagct
     6661 gggaacattt ttacatgata taggtaagcc tgacagtatg accttagatg aaaccggaag
     6721 agttcatttc acaaatcatg aaaaaatagg tgctcaaata attgacaata tgggaataaa
     6781 gttagagtta tcaacagaga catatagact tataagtaaa tatgtaagat atcatatgat
     6841 acttttgtct ctatataaga aaaatgattt gagtaggaaa gaattaatta atgtatttaa
     6901 cttagtagat gaggacacta taggtgtaat aatgcttggg tatgcagata tagtgtctac
     6961 agtaaaatta ttgggcaaga gtggagaagt cagtgtgtta aagacatata tggaatatat
     7021 tttaacaaat tacttgtata agagtaatta tacacatgta taaatttagt taatataatt
     7081 gagttttaga tgattaattg aagtttgaaa tatacggatt tcaaaaacat aaaagaagtt
     7141 gtctttgttg taaaattatg aaagacaact ttttttatat caaaaattga aattttatta
     7201 aggatactta atggtctatt aattaataaa ccattagtat ttaatttata ttacaatatt
     7261 gattttgctt gtattggcgt tgatagtata acagaggtct tagtagaacc aattttcttt
     7321 atagtatcaa tcacattttc taactcgtac atatctttta caattacttt taaaagtaag
     7381 caatcatcac ctgttatatg gtgacattct acaatcctag ggtcctttgc agctgactca
     7441 ataaattctg tatatccatt gcttggaaga gaaatatgaa taaatgcctt tataactctg
     7501 cctaatgaat ctgggttgac aatagcttta tatccttcta taacaccaga ctcttctaat
     7561 cttttgactc tttctgaaac tgcaggagaa gttaaaccaa ctatttttcc taagtccttc
     7621 atagaaattc tcccatcatc ctgtaaaatt tctatgattc tgtaatctgt aacatccata
     7681 aataaacagt cccccttaaa taaaaataat taatgctata aaactttttt agaatctatc
     7741 atttgtgttt ttaaatacca aagatttcta gataaatcaa ccttataaat gtgtggtttt
     7801 gaaagtcttt tgtattgttc ccagatagta cttaattcat attgtacatg attttttatt
     7861 tcaagaacag cttttttatt atatttgcat ctgcctttta tatacaatgg tttaagaagc
     7921 tctttaactt tgtaatttgt aaataccttc gttttccatg tataagtagg atggaagatt
     7981 tctaaaggtt tagactcatc tataacttca tcatgtaaca taatcaaatc tgcctctgcc
     8041 ttattgtctt cgttatatat tcttataact ttcttgtaac caggattatt tattttttct
     8101 ggattctcag aaatctttat cttaggttca agaactcctt tttcacaaga tgcagctaat
     8161 ttataaactc ctccaagaga aggtgaatcg aaagatgtaa tgagctttgt acctactccc
     8221 catgaattta tagtagctcc ttctgcttta agtgatgtta tggtatattc gtctaggtca
     8281 ttagatgcag tgatgctgat atctgaaaag ccagcattat ctaattgttt tttagcttct
     8341 ttagataaat aagctaaatc tccagagtca agtcttatac ccataggttt gtatcctttt
     8401 tcagaaatat ttttgaatac ttttattgca ttaggaactc cactgtttaa tacatcataa
     8461 gtatctacaa gtagtaggca tttatctgga taaacatcag catatgcttg gaatgcttca
     8521 agttcattat caaatttttg tacccaactg tgagcttgtg taccaattat aggtatatca
     8581 aacattttcc ctgctagtac gtttgcagtt ccagcacaac caccaactac agcagcccta
     8641 gccccatata tccctgcatc tggaccttgt gcacgacgta atccaaattc aaatacaggg
     8701 tctccttgag ctgcaaagca aactctagag gctttagtag caataagaga ctgaaaatta
     8761 actattgtta acaatgctgt ttcaataagt tgagcttgat ataaaggtgc cttaacagta
     8821 attaatggct cattagggaa catgatagtt ccttcctcaa cagcatatat atctcctgtg
     8881 aatttaaatt cttttaaaaa ttttaagaac ttgtcagaaa ataaatttaa gttttttaag
     8941 tactctaaat cttcatctga aaaatgaaga ttatctatgt attcaacaac ctgatcaata
     9001 ccacaaacta tagtataccc tccatcacaa gcgttttttc taaaaaacat atcaaataca
     9061 acaatgtctt catgaatatt cttttcaaaa tagccattta acatagtaag ctgatataaa
     9121 tcagtaagaa gtgttagatt tctcattatt tctctcctta attattatta aatattaaaa
     9181 attgtaaaaa ctcccacact tatactaaaa cataatatag tacaactttc aagtataaag
     9241 tattacctaa ctatcataaa attatttaaa gaggaggatg attataatag gaaaaatatg
     9301 gttttatatg gtatcgatag gaataatagg aagcttgatt tctaaaaata tgggtgaatt
     9361 aaataaagtt atattaagtg aaacatcaaa aggtatagag tttgcaataa gtctagctgg
     9421 tatcatggca ctctggatgg ggataatgaa tatcgcaaaa gaatcaggtt taattgaaaa
     9481 gataggtcaa aaactaaatc ctataatgag aagattattt ccttctattc caaaaggtca
     9541 taaagcaatg tcttatatag ttatgaatat tgctttaaat atgttgggtg ctggaaatgg
     9601 tgcaacagca tttggtttaa aagcaatgag tgagcttcaa actttgaata acaagaaaga
     9661 tacagccact aatgatatga ttatgtttat ggtaatcaat atatcatcta tacaaataat
     9721 tccatttacc ataatcaaac taaggatgga tatgggggct caaaatccaa gtgaaataat
     9781 ttttacgact ttatttgcaa ccataatatc tacagcagta gcaataataa catgtaaatt
     9841 ttttcaaaga agatatagat aaaggggatg tagatacatg gagatatttt caaacttact
     9901 tataccaata ataattctgt acatagtaat ttatggtaaa tataaaaaaa tagatgtgta
     9961 tgatagtttt gtaaaaggag caattgatgg attaaaagct gcatgggata tcctaccata
    10021 tataataggt atatttttgg caataggaat attcaaaact ggtaaaggtc ttgatatgtt
    10081 agaatggcta tttacaccaa tagcaaatat gatgagtata ccaaaagaat taataggtct
    10141 aataagtgta aaacctttat ctggaagtgg tgctttaggg atgtacagtg aacttgcaaa
    10201 tagagttgga ataggaagtt tagtagaaaa aatgggtgct acgattgtag gttcttctga
    10261 gactattttt tacacaatgg caatatacta tggaagtctg aagataaaaa atactagaca
    10321 tacattatca tgtgctatga ttagccatgt tgcaggtgtc atagcagctg tttttatttg
    10381 ctatgtaata tttgtataat ttgttgacaa tatgggaaaa attttataat atagtgatta
    10441 tatagaaaca aatagtaata caaattacaa gctatgaaaa gaagagtaaa taaaggtttt
    10501 ttctatcaga gagctaggtt aggtgaaagc tagtgtcaaa agctttattg aagatggtct
    10561 tggagctttt tatctgagca agtgtgctag ggtaaaacgg ttggacacgt tatagtctac
    10621 taaggtatct ataaaatgtt tctacatttc atgtgaaaca taactattat agatgaatta
    10681 gggtggtacc gtgaataatc tcgcccctat gttaactcat aggaggcgat tttttattat
    10741 ttaaatgaaa gaatcatatg attacgaacg ataaaaaatt aggaggtaaa taacatgagc
    10801 aaaccgagtt tttatgtaac aacaccaata tactatccaa gtggaggatt acacatagga
    10861 catacttatt caacagtagc tgcagataca atagctagat tcaagcgttt ctgtggatat
    10921 gatgtaaagt tcttaacagg aacagatgag catggtgaaa aaattcaaaa gaaagccata
    10981 gaacaaggaa tgtcagagat agagtatctt gatggaatga taaaagatat aaaggcctta
    11041 tggaatacta tggatatatc ttatgatgat tttataagaa ctacagaaaa aagacataca
    11101 gacataatac aaaagatatt tactaaacta tatgagcaag gtgatatata taaaggtgaa
    11161 tatgaaggta gatactgtac tccttgtgag agtttctgga cagaatctca attactagaa
    11221 ggaaataaat gccctgactg tggaagagaa acatatttag taaaagaaga atcttatttc
    11281 tttagattat ctaaatatga agacagatta aaagagttat ttaaagatga tagtttctgt
    11341 tttcctgctg ctagaaaaaa tgaaatggtg gcaaactttt tagacaaagg attagaagat
    11401 ttaagcgtaa ctagaacgac ttttgactgg ggtataaaag ttccttttga tgaaaaacat
    11461 gtaatttatg tgtgggtaga tgctttatgt aactatataa cagcattagg ttatatgact
    11521 gataatgatg aagaatttaa aaaatattgg cctgccaatg ttcaaatagt aggtaaagaa
    11581 atagtgagat tccatacaat aatatggcca gcgcttttaa tggctttagg tctagaagtt
    11641 ccaaaacaag tatttggaca tggatggata ctatttgctg atgataaaat gagtaaatca
    11701 aagggtaatg tggtttatcc agaacctata atagaaagat atggaataga cacacttaag
    11761 tacttcttat taagagagtt tgcatttggg caagatggaa gttatactca tagaaatttt
    11821 gtaacgagaa taaattatga tttagcaaat gatttaggaa acttaataag tagaactgta
    11881 gctatggttg aaaaatacaa taatggtata ataccaacag caaaagtttc aactgatttt
    11941 gatgctgact taaaagaaca agctgtttca actagagaaa actttgaagc tgaaatggat
    12001 aaaatgcaat tccatgaagc attagagagt gtatggaaat tagttagaag aactaacaaa
    12061 tatatagatg aaactatgcc ttgggcacta gctaaagatg aaacgaagaa agatgaatta
    12121 gacacagttt tatataattt atgtgaatct ataagaataa tcgcaacact aataaatcct
    12181 ataatgaatg agactgctaa taaaatatat gaacatatag gaataaaagg tcaagatgat
    12241 ataactacat gggaaagtac aaaaacattt ggtcttattg gagaaaatgt aaaagtattt
    12301 aaaggtgaac ctttattccc aagattagat gtagaaaaag agatagaaga attaactaaa
    12361 atgttctctg ggaaacctcc agtagaagaa aaacctttag agcataaaga agaaattact
    12421 attgatgatt tagacaaaat agagcttaga gtagggaaaa taataagctg tgaaaaacat
    12481 ccaaaagcaa ataaattatt agtatcacaa gttaagattg gaccagaaac aagacaaata
    12541 gtatcaggaa tagctgaata ctataagcca gaggatttag taggaaaaga ggttacagtg
    12601 gtatgtaact taaaaccagt taaattaaga ggtgtagaat ctcaaggtat gatattagca
    12661 gcaggtgatg atggagaccc atatgtttta ccatttacac aaggggctaa agatggatgc
    12721 gaggttcgtt agtaggtaat taaatagtaa ggagattaaa gatgttattt gactcacatg
    12781 cacatttaaa tgatgaaagt tttgatgaag atagagatga acttattggt tcattaaaag
    12841 ataaaggtgt agatttggtt gtaaatccag gagcagatat agagacgtcg ataacagcaa
    12901 ttgaacttgc gaaaaaatac gactttatat attcagcagt tggggtacat ccacatgatg
    12961 tatcaaaact agatgataca gcaatagaaa ctctaagaaa acttgcaact gagaatgaaa
    13021 aagttgtagc tattggagag attggattag attattatta tgattattct ccaagagaag
    13081 aacaaaaaga gtggtttaag aagcaaattg aattagctaa tgagctaaaa cttccaataa
    13141 taatacatga tagagatgca catggagata cttttgagat aataaagaat actaaaaatc
    13201 ctgaaatagg atgtgtactt cattgttata gtgggaatgt agagttagct agagaatatg
    13261 ttaagatggg ttgttatata tcaattccag gcacggttac ttttaagaat aataaaaaaa
    13321 ctagagaagt agtaagagaa atacctctag aaagattatt catagagact gattcaccat
    13381 atatgtcacc agagccacat agaggaaaga gaaacaatcc ttcccaagta tcttttgttg
    13441 ctgataagat agcccaggaa aaagggatat cttatgaaga agtatgtaga gttacaaaag
    13501 aaaatgcaaa gaaatttttt aatataaaat agacaaatta aatcttataa tgatatatat
    13561 aataagtcat tataagtata ggatgagagt gcctcaaaat gagtttttta gttcatgagg
    13621 cactcttttt tgtatgaaat caaatatatt ttcatcattt caacaatgaa aaagaagttt
    13681 atcatatttt gagatagttt gtttttattt atttaattca tattttaaaa tatattttct
    13741 taacattgtt aaaaaagaat ttacaagaga ttcattagaa ttaactcaac tctaatattc
    13801 acttaactta agttgtttat tatattatta aagagaagta aacgaaaggt agattaagga
    13861 ggttgaattt tgtatacagt tgatagtact aagatattga taaatatgaa cttagagaaa
    13921 ctagaaaaga tatactcaat gataaaagat acatcaagta tttctataat taaagaacct
    13981 aacttggcta cagtaatggt aagagctaat gaaagtgtaa aaaacacaac atttaattta
    14041 ggagagatat tagttactga atgtagtgta aaggtagatg aaagcttggg ttacggaata
    14101 gtttcagaaa acaataataa gaaagccatt tatttagcag ttatagatgc agttttacat
    14161 agcaataaca gtaaatttga tgagttaaag aattacataa ataaaagtgt atatgaagag
    14221 aacttaaggt atgaacaaga gattattgat gaatttagct tgattaataa aacgaaagtt
    14281 caattcaatg ctatggatta aataggagga gaatcatggt aaattataca caagaaatat
    14341 atagaaagat gctagatagt gcttcatttc ctgggaaatt aaataatata gataatataa
    14401 atatagaaaa taatacaaat ctattgaatg gagcaattgg tatagcaatc actttattag
    14461 accaagaagt taccttctat atagaaaatt atactcaaaa agatataaaa aatataagag
    14521 cacttacaat gtcaaatcaa atagattata gaaaatcaga ttatatattt ttagatatta
    14581 attcagaagt ggatatatta cagattaaaa taggttcttt tgaatatcct gatgaaagtg
    14641 caactatagt acatcaagta aatgatttat caacgtactc tcaaactaag tatataaagc
    14701 ttgatttgag tggtcctggt ataaaatcta aaaatagtat atatataaat ggaattagag
    14761 aagaatttat agaaagatta tctagtataa ataaagatta tccaatagga atagatttga
    14821 ttttagtaga taaaaaagga gaaattgcat ttataccaag gtcatcaaaa ttaagttggg
    14881 aggtattata gaaatggctt atgtagcagt taaaggtgga gaagaagcca tattacaggc
    14941 taaaaatata cttgagtttt atagggtaaa aggagatagc ttgcctatag atgtaaagca
    15001 gattgaggaa caaatgtctt atgctgtaga caaagtaatg tctgaaggaa gtttatacaa
    15061 caaggaacta tcagcattgg ctataaaaca agctcaaggt gatatattag aagcctcttt
    15121 ctatgtaaga gctttaaggt caacaatgcc tagaattaca tattcagaac ccataaatac
    15181 agaagaaatg agaataaaaa gaagaatatc agctactttt aaagatatac caggaggtca
    15241 gtatcttggg gcaactagag actatgaaaa tagaatattg aatgtagaat tattagaaga
    15301 agatgaaaaa aagaatagac attttagaga tagttttata aatgaattag aaacagtaga
    15361 tgaaatccct gaatttacaa aaatatctaa tatatttaga aaagaaaatt tattacaaga
    15421 agaagtttgt gaaaacaaat tggaagaagt tattgatgat attacaagaa atagtttaag
    15481 atttccagtt tctagggcag caaagttaca ggcattaact agaggtgaaa gcggagtagt
    15541 atcaggtttt gcttatgcta ttgtaagagg ctttggtgat gaacatccat atataagtga
    15601 acttagaact ggcaatgtgt ttataaaaat aaaacatccc atctatgaag atgaagaaat
    15661 aacaataggt gatatgttgg ttactgaatg tgaaatagtt tcaaaagcat cgcaaaataa
    15721 gactgaaaat tctaaaaata attcggaaga taaaaataaa atgtctttag gatatggtct
    15781 ttgtatgggg aacaatgaga ataaggctat atctatggct atactagaca aatctttgga
    15841 gccaaatagt gaaaaactag cacaagacga agaatttgta ttgcttcata tagatggaat
    15901 agattcatta ggatttatat ctcactttaa gcttcctcac tatgtagatt ttaaagcgga
    15961 tgtagaaaga ataaaaaagt ttgaggaggt aagtttaggt gatatataac tatggttttt
    16021 tagacgaaaa cacaaaaaaa gaaataagaa gaaagatatt aaaagcaata tcaatacctg
    16081 gttatcaagt tccctttggt tcaagagagt tgcctatagc taagggatgg ggtactggag
    16141 gtttacaatt aacactatca ttaattggta aaaatgatgt agtaaaagta attgaccaag
    16201 gaagtgatga ttctacaaat gcttgtaata taaggagctt tattgcaagt gtaagtaatg
    16261 tagaaaccac aaaagataca ttagaagcta cattgattca aacgagacat agaataccag
    16321 aagaaaaact taaatctaat caaatactaa tatttcaagt accaatacca gaaaccctta
    16381 gaatagtaga acctagtgaa gtagaaacaa gaagaatgca ttcagaagaa gattatagta
    16441 ggatgtgggt atatctttat gaagatatag ttagatttaa tgatatatct atagcagttg
    16501 aatatccatg taaagtaaat gatagatatt taatgaatcc atcacctata cctagatttg
    16561 atataaaaaa attaaatatg tcagacaatt tattcttgtt tggtgcaggt agagaaaaaa
    16621 gaatttatgc tattcctcca tatacaaagg tagaaccttt agagtttgag gattataagt
    16681 ttgaagagga aaagtttgaa ggaaaatact gtagtttatg taacagtaca aatacatttt
    16741 tagatgaagt atatgacagt gacactaatg aaaagtacta tagttgctca gatacaagtt
    16801 attgtgaaaa agttagatta aaaaataaca gtatagatgt gacaatagga ggtacttgga
    16861 atgagtaaaa taaatgactc taaaagatta gaaaatatag acaagcaagt attaatagga
    16921 agaaatatca atcttattta tggagatggg tgtgaaaagt gttttgaaag cacaggatat
    16981 gaaagcaata atatatgtaa gtattgtggt tctatagttg catgtaataa tgtaaattta
    17041 gaactttatg aaggagaagt ccttggaatt gtaggtgaat ctggttcagg aaaaagcact
    17101 ttattaaaaa tactgttttt ccaagaacat gcaaatagtg gagaagtata tatatcccat
    17161 tacaataaag acacaaatat actagagctt tcagaccaaa aaaagagata cataaagaat
    17221 cattttatgg gtattgtgta tcaaaatccc caccttggtt taaatttaga ctttagtagt
    17281 ggtggtaata tagcagaaaa attattgatg gcaaatttat ataatgttga aaaaataaga
    17341 gatagaggca aagaactttt aataaaaact aatatacctg tagaaagaat agaccataaa
    17401 ccaaaatact ttagtggggg aatgcaacaa cgagttcaaa tagcaaaagc tctttcaaat
    17461 aaccctccaa tattgctatt agatgaggtt acaacaggtt tagatgtttc tgtgcaagcg
    17521 gaagtattgg atttaataag agaaatccaa agagaattta agatttctat gatagttgta
    17581 tcccatgact ttgatgttat aaagatgctt gctgatagga caattgtaat gaaaaatgga
    17641 agtgtaattg agtctggtct tacagaccaa ataatggagg acccacaaca cccatatact
    17701 cagcaactta taaattcatt gctataaata tcgtttgtaa ataagcaaaa tgggggtttt
    17761 taataaaatg aaagaaacta tacttgaagt aaataatttt agtaaagact ttgagttaca
    17821 tgcattgaac aagactataa cggcatgtag taatataagt tttgaagttt caaaaggtga
    17881 gtttttagga ataataggta aatctggagc aggtaagtct accatattaa aaagtatcta
    17941 taaaacatat ataccaacaa ctggagaaat aatttttaat tcagaaatat atggtaatgt
    18001 agacctggct aaaattggag accgagaaat gataaatctt agaaagaaag aaataggata
    18061 tgtatcacag tttttaaaga cacttccacg aataactgca attgaactgg tagtacattc
    18121 tttaattgag agtgggtttg aaaaggattg ttcgtatgat atggcaaaag atatacttaa
    18181 ccaatttgaa ataaaggaaa atttatggga tgcgtatcca aataattttt ctggtggaga
    18241 aaaattaaga ttaaatttag ctcaagctat ggttaaaaag cctagacttt tgttacttga
    18301 tgaaccaact gcatcacttg ataatcaatc taaaatatat gtaaaagaaa aaatgttgga
    18361 gcttaaaagt caaggaacta caatgatagg aatttttcat gatatagagt ttatggaaac
    18421 tgttatagat aagaccttta ctatgacaaa agggactata agtgaaagtg gggtagccta
    18481 gatgataaaa ctaattcata atgcaaatat tgtattagaa gatatgattt tagaaaatgg
    18541 tcatttaatc atagagggag atacaataaa aaaagtatca aatgataaga ttgattacgc
    18601 atttgacttt aatgagatag atgaaataat agatgcaaaa aacttatatg taatacctgg
    18661 tattatagat attcacagtg atgccattga aaaggaaata gagccgagac caagtacatt
    18721 attaccattt aatatggcat tttatgaact agataaaaaa ctacctgcaa atggaataac
    18781 tacagtttat cattctatat ctttagggga tggagtagga gttagaagta ttgataactc
    18841 tttaaagatg attaaaaata ttgattcata taaaaatata gatagtaaga gcataaatca
    18901 taaagttcat ttaagatatg aagtgttgta ttatgaaggt ttagaaaagg ttttagaact
    18961 attagatgaa aataaaatag actacttatc aataatggac cattctccag gacaaggtca
    19021 gtatacaaat ccaacatttt ataaagagta tgctactaaa gtgtggggag ttacagaaaa
    19081 ttatgtagat acatggttag atgatttagt aaatctgcat gataatttag attggaataa
    19141 aatagctaat attataggta tagccaaaac taaaaatata aatgttgcat cacatgatga
    19201 tgatacatta gaaaaaatgg atttcataaa aaatataggc ataaatgtat ctgaatttcc
    19261 tataactctt gaagttgcaa aacattcaaa gaaattgggt gttctaactt gtttaggtgc
    19321 accgaatatt gtaagaggta aatctcataa taacaattta aaagcaatgg atgctatatt
    19381 ggaagattgt tgtgacattg tgtgttcgga ttatcttcca tcagctatga taaagtctat
    19441 gtgtatagtt gcagaaagaa taaataattt aaataaagca gtcagtttat ttacctcaaa
    19501 tcctgctaaa gcagttggta tatatgatga aagaggtagt ataaaagaaa ataaaaaagc
    19561 agatttagtt ttagtagata ttgatagtga atatccaaag gttgtaaata ctattgtaaa
    19621 tggaaaaaca gtttataaaa gggaggtata aagattgcta acagagttac attgtcatac
    19681 aagtatatca gataataatt ttactactga agaaataata aaaaaagcag cagaaaagaa
    19741 tataaatatc ttagcaataa caaatcatga cacattatct ggattggatg aagctcttgt
    19801 gcttggagag cattatggaa taacaataat accaggtata gaaatttcag cctatgatta
    19861 taaaaataga aaaagagttc atattcttgg atataacata gatttaaaca gtcaagaaat
    19921 aaaaaatttg tgcaatccaa tggtatgtga cagacataaa gcatctgtta agatggtaaa
    19981 taaaattata gatttaggat acaaaatatc tttggaagat gtaaagaaat attcatcaaa
    20041 gactggaata tttaaacaac atataatgaa agctcttata gataaaggat atacagataa
    20101 tatatattca agtctatata aagaattgtt tcatagagga aacggcaagg tatatgtatc
    20161 tttaaaatat gtggattaca gagatgcaat aaaagctata aaaaattctg gtggaatttg
    20221 tgtgttagct cacccgggtc aaatggataa ttttagcgct attgaagaga tggtaaaagt
    20281 aggattagat ggaatagaag tatatcatcc atctcacaac aaagaactag aaaaagagtc
    20341 gctttcttat gctaagaagt ataatctagt ggtcacagga ggctcagatt accacggatt
    20401 ttattctcaa cataattatg aacttggaag caagagctta aataaagaag atttatttaa
    20461 gtttaggtta gctttaggag gggtattata aatgtctttt ttacaagtaa aaaatgtagg
    20521 taaaagttat ggacaagtta aggtgttaaa agacatatct attgatattg aaaaaggaga
    20581 gtttatttgt ttactaggtc caagtggttg tggaaaaagt acactgctta gaataattgc
    20641 agggcttgag gataaacatg gtggaaaaat aataataaat gataaggata tgactaattc
    20701 accacctgaa agtagaaatt ttggtatagt ttttcaatca tatgcattat ttccaaatat
    20761 gaatgtttac aaaaacatag cctttggact agaaaataaa aacataagta aatctaatat
    20821 tgataaaaaa gttaaagaag ttctagaagt tgtagaatta agtggatatg agaaaaaata
    20881 tccatcacaa ttatcaggtg gacaacaaca aagggttgca ttagctcgtg cgattgcttt
    20941 agagccagac tttttacttc ttgatgaacc tttatctgca ttagatgcaa aagtaagact
    21001 taaacttagg gagcagatta gaagtttgca tagaaaacta ggcattacaa ctataatggt
    21061 aacgcatgac caagaagaag ctctttgttt agctgataag atggttgtta tgaatagagg
    21121 agaaataata caagttggaa cgccaaagga ggtatataaa aatccagaaa caccttttgt
    21181 agctgatttt ataggaacaa taaattttat agatgatggt attaataaga tagctattag
    21241 accagaagat ataaaagtag agtctaatag agattctaaa gataaggata taaaagtggg
    21301 agaaatttta gatatcgaat ttagaggatt taactataga attacagttg agtatcgttc
    21361 taagcagatg aaattagatg tagtttccaa agttgcagaa caaatgaaac tgtgtatagg
    21421 ttctaaaata aactttaaga tacctaaaga aggaattgta caatataaat cagagggatg
    21481 tgcttaatag ctaggggtga ataaatgata acatcaaaaa ataaaagaag aataagtgat
    21541 agcacaatac aaaaatattt cttgattttt tcggtaattg tactaatagt atttatatta
    21601 tttccattag tatcattatt aaaaaatgca tttatggata caagtggaaa ttttatagga
    21661 atttcaaact ttagtaaata tgttgaaaat ccaagtctta tagcatcatt taaaaattca
    21721 atttttgtat ctacagtctc atctttaata tcactatgtt tagcatttat atattcatac
    21781 gcaataacaa gaacaaacat aaagtttaaa gaatttttta aaactatggg aatgtttcca
    21841 ctttttgcac caactatgtt atatggtatt tcacttatat acctttttgg aaataaggga
    21901 atctttacaa ccatgggtct ggaagtacca ctatatggtc cattaggaat aattatttct
    21961 cagattctat ttacatttcc acaagctttt ttaatattat ctgtagcact ttcgatggct
    22021 gattacagac tttatgaagc agcagatagc ttgggtgcta gtgaatttaa gaaattttgc
    22081 aaaataacaa ttcctggtat aaagtactca ttacttagtt cattctttgt atcctttata
    22141 cttgcattta cagattttgg agcagctaag gtagttggag gaaactacaa tgtactggct
    22201 actgacatat ataaacaagt agttggacaa tttaacatac caatgggagc tactgtttct
    22261 atggtaatgt taattcctgt actaatagca tttacattag ataagatggc aagtaagaaa
    22321 caaggtatga ccataactgc aaagtctatg ccatataaga ttaaggaaaa taagtttaga
    22381 gatagagtat ttttaatagt atgtagtttt ataacattgc taatttttat tttaatattc
    22441 gtttcagtta taggttcagt tataaagtta tggccatata atttaagctt tacaatggaa
    22501 cactatacat ttaaaggtat tttgggaagt ggaataaaaa catatttaag cagtttgaaa
    22561 atatcaactt taacagcaat atttggaact atatttgtat tttttagtgc ttatatgata
    22621 gaaaaggtgg ataagtttcc taaattaaga caaacagctt accttttatc aatgatacca
    22681 atggccttac ctggcttagt tttaggtata tcatatataa ctttttttaa ctcagcaagt
    22741 aatccattaa attttttata tggaagtaca gcaatattag ttatagtaaa tgtagttcat
    22801 ttttattcag tttgttttat aacctcaaat tcatctttaa aaatgttgga taaagagtat
    22861 gaattagttg caaaatccat aaatattcca ttctataaag tattttttaa tataacagtt
    22921 ccaatgtcta taacatcaat acttgaaata gtagtatatt attttgtaaa ttcaatggtt
    22981 actgtttcag cattaatatt tttatataca cctcaaactc agactgcatc aatatcaata
    23041 ctaaagttag atgagatagg atatatagga ccatcagctg ctatggcagt attagtgctt
    23101 ttaacaaata taatagtaag acttttgtac gaatttgtaa caaagaaatt aaaaaataac
    23161 acacaaaaat ggcagcaaaa agatgttgca taggggaggt aaaaatgaaa tttaagaagc
    23221 tagtttcttt aggagtatta tcaacacttt tattaagtgt aataacagga tgtagtactg
    23281 attcatcagg ttcagattca aagtctgata gtaagacaaa aggggattta acagtttaca
    23341 cagcaattga agaagatagt atagagccat atttagctac atttaaagag aaatatccag
    23401 atattaaatt aaatattgtt agggcatcaa caggagatat aacagcaaga ttattagcag
    23461 aaaaggataa tcctcaagca gatgttgtat ggggagttgc agccacaagc ttattggttg
    23521 cagatgacca ggggatgtta gaaccatatg ctccaaaagg ttctgaagaa atagagtctg
    23581 catttaaaga tgataaagaa gttccttctt gggttgggat agatgcttgg atgacaggta
    23641 taacagtaaa cactaaagaa ttaagtgata agaacatccc agttcctagt tcttacgaag
    23701 atttaataaa gccagaatat aaaggtctta tatctatgcc taatccatct tcttctggta
    23761 cagggtactt aacagtatca gcccttatac aaattatggg ggaagaaaaa gcatggcagt
    23821 atatggataa gttacatgag aatattggtg tatacactca atctggttca gctccagcta
    23881 catcagcagc ttcaggagaa tatcctattg gtatatcttt tggatataga ggtataaagt
    23941 taaaagagga aggctatcca gtagaagtag tatttccaaa agaaggttct ggatgggata
    24001 tagaagcaaa tgctcttgtg aaaaaagata atataaaaga agcatcaaaa gtatttttag
    24061 attgggctat aagtaaagat gcaatgaacg aatactctaa aaactatgca gttactacta
    24121 tttctacagg aaatccaata ccagaaggat tccctaaaaa gccattagag caaatgatag
    24181 ataatgattt aaaatcagca gcaaaaaata gagaagatat actaaataaa tggatatcaa
    24241 aatatgatgg taagacagaa aaagagagtt aagtaaaact atacaaatgg agtaaaaaga
    24301 aaaatttttt ttaagtagat tttattatta taatataagt tgagaataat ataggtcaag
    24361 aaaagtgaat attctataaa aatgtataga gtaagtatac cattcagttt gaatggtata
    24421 ttttttattt ttagagatta atttagaaat agatatacta cagtttaaaa tagtatattt
    24481 taatttcatt attaaagtat agatgttata tataaagtaa ataagatatt aaataattat
    24541 aaactaaagt aaataaaata ttgagcgatt attaaaaaga tatatatata atttaatttg
    24601 agcagtttgt tatatattat aaaaaaagag aaaaataaaa ggtaaattgt ttctggataa
    24661 cttaaaattg gaagtaagaa tatttaacta gagaagaatt atttaagttt aggttagctc
    24721 taggagtagc tgattttata ggaacaatag attttatgga tgatgatata aacatggtag
    24781 caattagacc agaagatata agggtagaat ttaatagaga tttcaaagaa attatagacc
    24841 tcaaactcag accgtatcga tataaaaact aaagttagat gatatagtgt tgtagatagg
    24901 accatcagct gttatggcag tattagtgct tttaacaaat ataatagtaa aacttttgta
    24961 tgaattgata ataaaaaaat taaaaaccaa gacataaaaa tggcaacaaa aagaagttga
    25021 ataagggagg taaaaatgaa atttaagaag ttagtctctt tgggaatatt atcaacactt
    25081 ttattgagtg taataactgg atgtagtaat gtttcatcag gttcaaactt aaagtctaat
    25141 aataagacaa aaggagagtt aacagtttat acagcaattg aggaagatag tatagataca
    25201 tacttagcta catttaaaga gaaatatcca gatattaaat tgaatgtact tagattatca
    25261 gtaggaggta taacagcaag attattagca gaaaaagata atcctaaagc agatgtgtta
    25321 tggggtgttg cagctacaag tttgataatt ttagatgaca aagaaatgct agagccatac
    25381 gctccgaaag gctttgataa ggtaaattct gcatttaaag atgataagaa agttccttct
    25441 tgggttggaa tagatgcttg gatgactggt ataacagtaa atactaaaga attaaaagct
    25501 aaaaatatat cagctcctag ttcttatgaa gatttaataa agccagaata taaagatctt
    25561 atatctatgc ctagtccagc ttcttcagga acaggatatt taacagtatc agaactcata
    25621 caaattatgg gtgaagaaaa agcatggcag tatatggata aattgcataa aaatattggt
    25681 gtatacactc agtctggttc agctccagct atattagcag cttcaggaga atatcccatt
    25741 ggtatatctt ttggaaatag aggtataaag ttaaaaggtg aaggttatcc agtagaagta
    25801 gtatttccaa aagaaggttc tggatgggag atagaatcaa atgcacttgt gaaaaaagat
    25861 aatataaaag aagcatcaaa agtattttta gattgggcta taagtaaaga tgcaatgaat
    25921 gagtattcta agaattttgc agttactaca attgacacgg gaaatccggt gccagaagga
    25981 tttccaaaga atccattaga acagatgata gataatgatt taaaatcagc agcaagaaat
    26041 agagaggcta tactaaataa atggatagaa aaatatgatg gaaagacaga aaaagagagc
    26101 taagccttgc aataaaattt agtacaaaaa gcgcctagaa tataagtttt atatctaggc
    26161 tcttttgata tatttattta aaatgcatat ttctatataa aaataaatag tttagtacct
    26221 tgattaaatt aaataaaaac cttaaaataa agagatgtaa agaaaaacta aaaacgaata
    26281 aaaggtgaat ttatatgata aaagaaataa tagtagtaga gggtagagat gacgttacag
    26341 cagttaagag agcaatagat gcagaactta taactacagg tggatttgga tttccaaaag
    26401 gtgtaatgga gcgtataaaa gctgctaatg aaagacgtgg tgttataata tttacagacc
    26461 cagattttgc aggtgaaaaa ataagaaaaa aaatagcatc agaagttcca ggatgtaaac
    26521 atgcatttct accgagagag gaagctaaaa aggatggaga tataggtatt gagaatgcta
    26581 ctcctcaaag tataatagca gctctgaata aagttagaac tgaaaataca gaaaaaagag
    26641 atgaatttaa gcaagttgac ttaattagaa atggtcttat aggtaatgaa gaagcatcac
    26701 ttagaagaga tgcacttgga aaaatacttg gaattggata tggaaatgca aaacaatttt
    26761 taaatagatt gaataattat ggagttgaaa gagaagaatt tatagatgca ttaaaacaaa
    26821 tctaaacgta atgtttaatg tatgaaaaat atgtatataa aataaattgt ggaattacgg
    26881 ttaatttaag atgaattatt tataatatac accttatttt aaatcaatgt aaatacatat
    26941 aaataagtat aattaataaa attaaatatc aaaataagtt aaaaaggagt aaataatgga
    27001 tagactatct tcacataatg caacaaagga agtagtacaa aaatataatt ttaaattttc
    27061 aaagtcttta ggtcaaaatt tcttgataga tagtaatata attgataaaa tcttatctgg
    27121 agctagaatc acaagaggag ataatatcat agaagtagga cctggtatag gaactcttac
    27181 tcgtgagatg ggtaaaatag cagaaaaagt agtggctata gaaatcgata gaaatttaat
    27241 tcctatattg aaagatacct tgtcagattt agataataca gaggttgtaa atcaagatat
    27301 actaaaagta gacatacagg aattagtaaa agataaatta aatggtgggc cagttaagct
    27361 tgtagcaaat cttccatatt atataactac tccaatagtt atgaaatttt tagaggaaga
    27421 catacctgta acagacatag tagtcatggt tcaaaaagaa gttgcagata gaatgaatgc
    27481 tattccgggt actaaagatt atggggcatt atctatagct gttcaatact attgtgatac
    27541 agagattgtg gcaaaagctc caagacatat gtttatacca caaccaaatg tagattccac
    27601 agttataggt ctacatgtaa gagataaaag aaaatatgat gttcataatg aagacatatt
    27661 ttttaaaaca gtaaaagcat cctttggaca aagaagaaaa actcttctta attcgttggg
    27721 aggtcttggt tttcttaata aagatgaaat aagagaagta ttaaaagaag ctaatataga
    27781 cgaaaaaaga aggggtgaaa ctcttagtat agaagagttt tcagttcttt caaatataat
    27841 aaatacaaaa gtatcttcta aatagaaggt acttttttta attttgttaa catatattgt
    27901 ttagagaaac tgtgttaagg ggggattgca gtgggttcta aaagaaagtt taaaagagac
    27961 tatataatac tagaagctaa agacataaac tttagataca aagaacgagt actgccaaaa
    28021 gcttttgcaa aagttgaagt aaatgatgaa aaagcaatta ttgcattata tgtagaaaat
    28081 ctaaaatatg ttaaagatgg gtataaagca gtagcaataa aagatgacca tggattaata
    28141 gacttaggaa atataatttt aaatgaacaa ggaagaggtg aatttgtttt agatttagaa
    28201 gattatgatg atgagataaa aggtattgca ttattgtatg aaagaaatat acctttaatt
    28261 ggatttaaag gaaataagct tgaaaattat gaggacatat tatttcaaga ggtagaggaa
    28321 gaagaatatg aagaatatga agagttggaa gaagaagacg aagagataga ggagaatgag
    28381 gaaagtgata gagacgaaga tagtgaagaa gaatatatta tagaagaata tgatgaagat
    28441 gagtatgaag actattggga agatgatgaa gatattgaag aaggagagtt aaaagcaaga
    28501 acggaagtag aagattctga tgatgaggaa atagaagagt tcaataatta taaggaaata
    28561 gaaaattata atagggttaa agtacaggaa gaatatatag acatagaata tgatgaagaa
    28621 gaagaggaag aagaagtttt tgaagtaaat agagaagaag ataggtttgt ttcctcaaaa
    28681 cctactaaat caaagaaagt tcaaaaagat cagaataata ttgaaaaaat aaaaagagct
    28741 aatggagtaa gtcaaggaga gagtggaaat aaacaaacca gtacattact tatgccaaga
    28801 caaataaaaa aaggtttgaa attatttaaa gaagtaaaac cttttgtaac agattatata
    28861 gataagacaa gatggtggaa aatagagata aatcctacaa cactgtgtgg atatacaatg
    28921 ccttatttag gatatttaaa cgtattgaat tacactatgt atagtgatgc agttttacat
    28981 tcatataaat acagacacta tttatttgga gttcagtatg atgaatataa taagagaaaa
    29041 cattatattt atgctatccc aggaaataga aatgaacagc cagacaatgg aagcacagga
    29101 tttttaagat atcaagcttg tgataataga acaaatagtt taggatattg gctatgtttt
    29161 atagattcta gacaaagaaa tatagttagg taaaaataat aaaaatgaaa aaatttagac
    29221 tcaattctta ttttactgaa aaaattaatg aaatgtagta caaaacttta aaaactattg
    29281 ataatattta aatattacac tacaatatat cttgaaatac ctattatatt atggaggaaa
    29341 attatgataa acgagcaaag aattttaaat gagtttcttg aattagtaca gatagatagt
    29401 ttatctttaa aagaggggaa tgttgctaaa gtattagtta aaaaattaga agaaataggt
    29461 tgttcagtag taatagacaa tgctggtgaa aaagcaaatg gagaaactgg taatataata
    29521 gctacattaa aaggaaataa agaaggaaag aaaatattat ttagttcaca tatggataca
    29581 gtaactccag gtataggggt aaaacctata gtggatgaag caaatggaat aataaaaagt
    29641 gatggtacta caatattagg ttctgatgat aaagcaggta tagcagctat attagaaggc
    29701 ttaagatata taaatgaaaa taacatagaa catactgata tacaagttgt attctctata
    29761 tgtgaggaat gtggattagt tggagctaaa aatttagact atggaaaaat agattctgaa
    29821 tatgcattta tattagatag tggtggttct ccaggtgaaa taatagtaaa agctcctgca
    29881 caagatgtaa taaatgttaa gatattagga aagactgctc atgcaggtct tgaacctgaa
    29941 gctggaataa gtgctataat ggtagctgcc agagcaatag aaaatatgaa tttacttaga
    30001 atagacgaag aaacaactgc taacatagga attataaacg gtggaacagc tacaaatata
    30061 gtaacaggag aagttaatat agttgcagaa gccagaagtc taaaagaaaa taaattagat
    30121 gttcaaacta aacacatggt agagactttt gaaaaagctg cgaaagattt tggagctcaa
    30181 attgagatag atgttaatag agcatacaca ccaatagatg ttagtgagga ttctgaaata
    30241 ataaaacttg caaagaaggc tttttcaaac ttaggtatag aaggtcatac tgaatctaca
    30301 ggaggaggta gtgatacaaa tatattaagt aagaatggta tcgaagctat aactttagga
    30361 attggtatga aaaatgctca tacactaagt gaacatatag ctataaaaga cttatatgat
    30421 tctgctaaaa tggtagtgga gataataaag gaagcataaa tttaaataat agtgtataat
    30481 atatatatcg cctagcttaa gctaggtgat ttttcatttt atagaagatt gataatctct
    30541 attgaaagca aagagtatac atttgcatat aagagagtgt ttaatttatg ttcaaatgta
    30601 ggttcttaat aatatttaga ttgtttcata agggaggaat aaatatggaa acaaggtatg
    30661 aagaagcaaa taaaataaca atacaatcaa tactttggaa tatagtatta acaataatta
    30721 aggttatagc tggtgttatt ggtaattcta gcgctatgat tgcggatgga ttacattcag
    30781 catcagatat tataagttct ataggagtac taataggcaa ttatgtatct tctagacctg
    30841 gagatagaga gcataattat ggtcatgaga aagcagagac attagtatca tttgtgttat
    30901 caatattgct tattttcgtt tctataacaa taggtataga ggcaattaaa tctttattta
    30961 acttagatgc attaagtgtt ccatcaatat taccattagt agtatcagtt atttcaatcc
    31021 tgataaaaga gtatcaatat agaataacaa taaaagttgc taaaaagata aattcaccag
    31081 ccctaaaagc tgatgcttgg catcacaggt cagatgcttt atcttcagta gctgctttta
    31141 taggtatagg tggttctatt ttagggttta aaccattaga cccaattgcg tcagttgtag
    31201 tggctatatt tgtagctaaa gtaggaatta gtatacttat aagttctgtt aatgaattga
    31261 tggatgtttc agttgatgaa gaagagataa aagaattaaa atttattgta gcagatacag
    31321 aaggtgttaa aaatcttggt gatataaaga ctagaaaaca tggagctatg gcatatgtag
    31381 atttgactat atgtgtggat gaaaatttga cagttaagca aggtcatgat attgctacca
    31441 agcttgaaaa acatataata aaacatatgg aatttgtaaa aggtataaca gttcacgttg
    31501 aaccatgtac taattgccaa ggaaataagt gtaataatta attaaaactt aaaaaaaagt
    31561 gtaaaaagtt atataattgt tttatgatta taaactctag gggtggttaa atgagcaaga
    31621 aaagaaaact aaagaaaaaa gctgcaatat taataggagt agttgttttc tttataatat
    31681 actttatatc ctttagaata ggaataaata tggaaaagga taaaagtgaa gtgccaaaga
    31741 aggtagaaaa agaagaagaa gataataggt ctttaaggac tcaaataaaa gagaagaaga
    31801 aggtttatat atcagataaa aatatagaaa acataaaaat tgaagaagat atgtgggatg
    31861 aaataaagtt atttttctca gattttaaga aagtaagaaa tactacttct tcttacgaag
    31921 cagtttatga aggttattct gatgatggag ttaaattttc tactgacctt aactttttta
    31981 gagtatatac tgtaaataaa gaagaatatt ataaagtacc agttagttct aaggatgctt
    32041 ttaagaaact tttagatgag agtatatata cttcgtttga ccttttaagt cattataaag
    32101 attggaaaga ggttactata actcatggaa aagaaattaa aaaagttcat agatggaaat
    32161 ttgatgattt agcacataag atgatttcaa agagggttgt aggaaaagtt caacctgaga
    32221 aaagtaagga aagaagtgac tataatttta ctataaatat aaaaggtgat aattttgatg
    32281 taaaagttga tacaatggga aaagattatg taaaagttac ttctaagaaa aatgtatctt
    32341 actatgaggt tcatacaagt ttatttgatt accttaaaaa tgagatattt gaaattggaa
    32401 agaaataaga ctttaagaag gctatcaaat tagatatttg atagcctaaa ttattttata
    32461 tattattttt caaccaacaa gtctgcaacc ttataaattg gaccagcacc agcagttatt
    32521 actaaatcat tatccttaac attttcacgt aagtatttta ctatatcttc aaattctttt
    32581 atatagatgg catctacatt gttttgatat aatttctcaa ccaagtcctt agaatgtata
    32641 tctcctgggt ctttttccct agcagcatat atatctgtta tgataacttt atcagcagca
    32701 tagaatgcct ctgaaaattc acctaaaaga gattttgttc tagtataagt atgtggctgg
    32761 aagatacacc ataaagttga tttttttaat tttttggcag cagctaaagt tgcttttaac
    32821 tcagttggat gatgtgcata atcatctact actaaagcat tcttatagta ccctttagtt
    32881 tcaaatcttc ttccgacacc tttataaatt tttatatttt ttcttatagt ctctaagtca
    32941 ataccagaaa caagagctgc cattatggca gaagaagcat tgtatatgtt atgaagacca
    33001 tatacagaaa gttcaaattc tcctaaatct cttccttcat attctattct aaatattcca
    33061 tgaccactat tgtcaaagtg aatatctttt attacagcat cattgtcaga atctctgccg
    33121 tattttataa tagtagcttt aacatcatac aatatgtcat caatattttc atcatcgcca
    33181 tttattatga aatagccttc tgggggtaat aattttccaa atttgttaaa agaagccttg
    33241 atttcatcta ttccagagaa ataatcaaga tggtcttctt caacatttaa aactatagat
    33301 atctttgggt taaaattaag gaaactatct acatattcac atgcttcagt tataaagtgg
    33361 ttggaattac ctatcttaac attaccacct atcatactta agttaccacc aactagtata
    33421 gttgggtcta agtctgcata ttcaaagatt gtagataaca tagatgttgt agaagttttt
    33481 ccatgtgttc cagaaactgc tatagaattt ttatattccc tcatgatttg gcctaaaaaa
    33541 gttgctctgt tcattaccaa tttatttttt tctttagcag ccacaagttc ttcattgtct
    33601 ggatgaactg ctgctgtata aacaaccata tttacatcat ctgatatatt atcttttttc
    33661 tgaccaatat aaatagttgc cccttggtcc ctaagtttgt ctaataggta tgattcgttt
    33721 gaatccgaac ctgaaacttg ataaccttta ttgatacata tttcagctaa tgcactcatg
    33781 ctgataccgc caattcctat aaagtgtata ttcataataa aaccaccttt ctttttaatt
    33841 aagtcctaca atatgaacta tttctgtggt ataataatat aatgttcaat attttataat
    33901 taatatgcat ataatattat atgtatttta tttttgaata taataaaaca taagtaatat
    33961 tataccacaa taagaattgt tatgcattag ttagtttaac gttatataaa ggtacttgta
    34021 ggaggaaata ataatgaaat ttaaaagaac agagagaatt ggagcaatag ttaaaatact
    34081 gtctgataat ccaaataaaa tatatacttt aagttatttt acaaatcaat ttaatgcagc
    34141 aaaatcaaca ataagtgaag atttattagt tgtaaaaaat gtatttgaga agctacattt
    34201 aggtaaagtt ataactattt caggagcagc aggaggagta aaatatatac ctaaaacttc
    34261 tatagcagaa aatgcagagt tcttaatgga attatgcgag agaatatgtg acaagtctag
    34321 aatactatct ggtggttttt tatacttgat tgacctaatt tacgacccta caatagctgc
    34381 taagatagga aagatattcg catcaaatat tgagtatgta gatgcagatt atgttgtgac
    34441 aatggaaaca aaaggtatac ctatggcact tatgactgca aaagctatga atttacctct
    34501 agttataata agaaaagata taaaggtatc agaaggtcct acacttagca tgacatatgt
    34561 gagtggaaac agttctaaag ttgaaagtat gagtttgcca agaaaagctc ttaaaccaga
    34621 tagtaaagtt ataattatag atgatttcat gaggggtgga ggtactataa aaggaatggt
    34681 agaccttatg aatgaatttg gtgcagaggt tataggtact ggagtattca tatctacaac
    34741 gaatccttca gaaaaaatgg taaaagatta tatttcattg attcaattgg atgttaatgg
    34801 agataaaata gtagtagaac caaacttaaa gacttttaaa gatgaatata gaaatgaaga
    34861 tttagacgaa gaagaagatt cagaatttga atttgagata gatgaagatt aataaaaaaa
    34921 atatttagaa aaatatgtaa aaataaaaag aggatatccc tagttgttca tagaattatt
    34981 taaaaaacag tttatattaa tttattccag cgataataat tttaatataa attaatttct
    35041 gtcaaaatca aagggggata ttttggtatg aagataactg acgtaagagt aagaaaatta
    35101 acagaagaag gtaagatgaa atgtatagtt tcaataactt tcgataattt gtttgtagtg
    35161 catgatataa aagttataga aggccataat gggctattta tagcaatgcc tagcagaaaa
    35221 gtaggcgaag gaaatttcag agatatagct catccaataa atgcagaaat gagacaagtt
    35281 ttagaagatg cagttttaca agcgtatcat gaagcattag ttcaatggga agtagctgct
    35341 gaataataat aaatatataa aatggagaga gcccgaacat ttaggctctt tttaaatgta
    35401 gaatttctat taaaatatgt actttttagt aaaaaagtgc tatattatta gtgataatgt
    35461 atatgttgta tacaaattgt tagataaatg tattataatg tatattgatt aagagaataa
    35521 tacgaataaa attaaattag attgaatgga gtgtatcaat gaactttaaa gctataatcc
    35581 ttgctgctgg caaaggaaca agaatgaagt ctaaataccc aaaagttata cataaagtat
    35641 gtggaaaaga aatggttaac catattatag atgtttcaaa aaaatcaggg gtaaaagata
    35701 ctgtcgtgat tttaggacat gaagctgatg tagttaaaga aaagcttgca gaagaaatta
    35761 taatagccat gcaaacagaa caacttggga caggacatgc tgtaaagatg gctaaagaat
    35821 atattaatga tgaagataca atagttgtac tttgtggaga tactccactt ataaaagaag
    35881 agacactaaa gagactattt gaatatcata tagaaaataa atatcatgct acagttctta
    35941 caacaagagt tggaaatcca acaggttatg gtagaataat aagagataag aagggtgacc
    36001 ttcttaaaat agtggaacaa aaagatgcaa attcagaaga aaagatgata agtgagataa
    36061 actctggaat ttattgtttt aatggaaaga gtcttagaga agcactagat ttgctaaata
    36121 ataacaattc acaaggtgaa tattatttaa ctgatactgc taaaataatg agagataaag
    36181 gattaaaagt tggtgcattt gcaggttcaa ctattgaaga acttatgggc gttaattcaa
    36241 gagtagaatt atcaaaggca gaagaaatta tgagacgaag aataaatgaa tctcatatgg
    36301 taaatggagt aactataata gacactaact ctacctatat agaatctgat gttatgatag
    36361 gcaatgatac tataatatat ccaggtgtta tgttacaagg aaaaacaagg ataggttcag
    36421 attgtataat tggaatgaat tcatctataa caaattcaga aataggtgat ggtacagaaa
    36481 taaaaaattc aactataatt gatagtaagg ttggagaaaa ttctactgtt gggccatatg
    36541 catacttaag accaaagagt gacttaggaa ataatgtaaa aataggcgat tttgtagaag
    36601 taaaaaatgc tattatagaa gatggctcaa aagcatctca cctttcttat ataggagatg
    36661 cacatgtcgg taaaaatgta aatattggat gtggagtagt atttgtaaac tatgatggta
    36721 aaaataaatt taaatcaata gtaaaagaca atgcgtttat aggttcaaat tctaatttag
    36781 ttgcaccagt agttgtagaa gaaaaaggat atatagcaac aggttcaaca ataacacatg
    36841 atgtcccaga tggtgctttg gcaatagcaa gagaaagaca agttatcaaa gaaggatggg
    36901 tagaaaaaaa gaatcaaaaa gacgaccaaa gtaagtaatt atgtagttta ttattttggc
    36961 taaaaaattt agctcgaaat tattataaat tatattcatt agtattttaa aattttcagg
    37021 agggttacat aaatgaatac tagcggaagc gagattaaaa ttattgcagg taattcatcg
    37081 aaagagttag cacaaaaaat agctgactat ataggtgtat cagtactaga ttgtgaagta
    37141 ggtacattta gtgatggtga aatatgtgta aacatgaatg agacagtaag aggttgtgat
    37201 gtgtttgtag tgcaatctac taacagccca gtaaatgata acttaatgga gttattaatc
    37261 ttaattgatg cgttaaagag agcatcagca ggtagaataa cagcagttat tccttactat
    37321 ggatatgcaa gacaagacag aaaggctaag gcaagagatc caatcactgc taaattagtt
    37381 gcaaatttaa taactgctgc tggagcagat agagtattaa caatggattt acatgcagct
    37441 caaatacaag gatattttga tataccatta gaccacttac taggtggaac aatattagca
    37501 aattatttta atgaaaagaa aatagaagat ttagtagtag tatctcctga cttaggaagt
    37561 gttactagat caagaaaatt tgctaatact ttaaatggag aagttccaat agctataata
    37621 gataaaagaa gaccgaaagc taatgtatgt gaagttatga acttaatagg tgatgttaaa
    37681 ggtaaaaatg ttatactatt agacgatatg atagatacag caggaacaat agttaatgct
    37741 gcaaatgcac ttaaagagtt tggagcaaaa gatgtttatg cttgttgtac tcatggtgtg
    37801 ttatcaggtc cagctattga aagaattgct aattcagaaa taagtgagtt aatagttctt
    37861 gatactatac aacttcctga agagaaaaga atagataaga taaagataaa aacagtagct
    37921 cctttatttg gagatgctat aagaatgata ttctctaatg aatcagtaag taaattattc
    37981 taatttattg tatttatgag agttgtttaa aaggatataa accttttgag caactctttt
    38041 ttgattttat acttatggaa tgttattttt ttcttgttag aaaggtatat attattgtaa
    38101 aaagagatta tagtttaaaa ttatgtatat ttaagtaaaa taaacctaat aaagggtata
    38161 ttattcaaaa tattatgaat ataaaaaata ttacaaaaaa gtattgaaaa aattcagatt
    38221 atgtagtatt atgtaaatat aaataaagaa agaggtgttt ccaatgggaa ggttagaaga
    38281 tgaaccccta ataattaaat gattcagtca caatctaaag tgaatataaa aatctattga
    38341 aagtttattt ataagaattg aaaatagtat ctattctatc tttagtgttt gtgagagggt
    38401 tctggattat ataagattac tgtaaagagt aattttgcac aataagcata tctgtaaatg
    38461 aagagtttcg tttatataat gattgtggct gaatcataac tataatagat agaatgttta
    38521 taatagatga ttttataaaa tactatattg taatagcttt tagctttcaa ataaatatta
    38581 gcaaaggatg gaaatgacaa tgataaaact aaatgataat ttataaatat ctccttacga
    38641 tatataataa ttgtagggag atgtttcttt ttttgtatag cataattttt ctagaaattc
    38701 tgtttcaata tgtaaaaagt tggtatatat aaatagtata aacagtgttg ctaaaatatg
    38761 gtagatatta tataatataa gtggatatgt atatacatta tgagttatat aatttgaatt
    38821 taataaaata gaaacgttga tttatgttct gtaatgtggg caccttggag catattgagt
    38881 tagtggtgca accggctatg aaattgtatt tatttataaa tactattatt ttcatagctt
    38941 tttttattta aaaaatggtt atatgttaga aataaatttg gttagtacgt ttaaataatt
    39001 ttacttagat ttttaaccag atatattgta agtaagtatt aattaaaaaa tttaaggggg
    39061 aataaaaatg aagttaaaaa agaataaaaa aggtttcact ttagtggaat tattggtagt
    39121 aattgcaatt ataggtatat tagcagtagt ggcagttcca gctttattta gtaatataaa
    39181 caaggctaag gtagcaagtg ttgagtctga ttatagttca gttaagagtg cagcattatc
    39241 ttattattca gatactaata agataccagt tacaccagat ggtcaaactg gtttaagtgt
    39301 tttagagact tatatggagt ctctgcctga taaagctgat ataggtggaa aatataaatt
    39361 gattaaagtt ggtaataaat tggtattaca gataggtaca aatactgaag gagttacatt
    39421 aacagaggca caatcagcaa agttattgag tgatataggt gaaaataaaa tatatacaag
    39481 cgctacaaca aatagtttgg gaaatccatt aacaagtaat acaaaaatag ataataacgt
    39541 tctatatata gtacttatag ataatactgt gatggacaca acaaaatagt taaaacaata
    39601 tttttataaa aatattgtaa atttaatgaa aaatataata taaaagacag gaagaaaatc
    39661 ttcctgtttt tttatactat tttctttaat gttcaattat gaatgatgat ataattgaga
    39721 tagtaaagga gtgaaacctg tggctaaaaa agttagaata ggagacaaac tggtcgaaaa
    39781 aggatatata acagaagaac agcttaaatg ggcactatca gaacaaaaaa acagtggaaa
    39841 aagactagga gaatttctag tacaagaagg gcttatagat agtaacttac taataagtgt
    39901 attaaaagaa ctcttggata tagaaagtat atttttagaa gggacagaaa tagacacttt
    39961 agctacaaaa atggttccag aaaatatatg caaaagatat actgtatttc catttaaaat
    40021 tgatggaaat aaaatatgtc tagccatgtc agacccacaa gatagagaag cagttcaaga
    40081 tgtaaggcgt atgtctggta aagacgtaga gatatttata tcaagtacag aagatataaa
    40141 caaagcaata ggtcatgctt atgcacattc agaaataaat aaggcaatga ctgagtacaa
    40201 caaaaataga actggtggag taagagaaac agtaatactt gaagaagatg taaatgctgc
    40261 tccaatagta cgattagtaa ataacatact agaaaatgct gttagaatgg aagcaagtga
    40321 tatacatata gaacaaagtg aaaattacat gcgtgttagg tttaggatag atggaatgtt
    40381 aagagaatat atgaggatga actcagcacc atataaggca gtaatcagcc gtatcaagat
    40441 aatgtcagat ataaatatat ctgaaaagag aataccacag gatggtagaa tctatttaaa
    40501 agtagataat aaacccatag attttagggt ttctacaatg ccaactaaca gggatgaaaa
    40561 gatagctatg agagttcttg ataagagtaa ttttatggtt agtaaagaag tactaggaat
    40621 agacgaacat ggctctaaga tatatgatga attgataaac actccttatg gtcttatatt
    40681 ggttgttggc cctactggaa gtggtaaaac cactacattg tattcaatgt taaatcaact
    40741 aaatacagaa aatagaaatc tattaacaat agaagaccct atagagtatg aattacctgg
    40801 tgtaaatcaa tctcaaataa atgaaaaggc agggcttact ttcgccagcg gacttagagc
    40861 ttttatgcgt caagacccag atataataat ggttggagag ataagagata ctgagacagc
    40921 agaaatagca attagagctt ctcttacagg acatttagtt ttaagtacat tacatgcaaa
    40981 tacagcagtt ggagcaattt cacgtctttt agatatggat gtggaaagtt ttttaataac
    41041 ttcatctgtt ttaggtgtaa tatctcaaag acttacacga aaaatatgtg agcattgtaa
    41101 ggtttcatat gaagcagata ttggagaaaa aaaggctctt ggtattgatg taaatgaatc
    41161 agtaactatt tatagaggaa aaggttgtga aaggtgtaat aatactggat ataaaggacg
    41221 tctaggtata tttgaaatgc ttgaaattac tccagaaata aaagagttaa tagattcatc
    41281 tgcaaatcaa agagaaattt taaagatggc tagaaaacaa ggtatggtta gcttaaaaga
    41341 ggatatagtt aaaaaagttt taaatggaaa gacaacagta gaagaaatga ttagaataat
    41401 tttgatgact gattaaagga tgatattatg aaaagtttta aatacacagt aataaaagag
    41461 gacggaaaaa agcaaactga tgtgattgaa gccaacgatt ttaatgaagc tagaaatctt
    41521 cttagaaaga gaaatcttag agttattgaa atcaaagaaa gcaaaaataa aaatataaga
    41581 ttatctagta gaaagagaaa aaaagactta ggagctgacc agataagcca cttttgtaga
    41641 cagtttgcta ttatagtatc ttctggtata aatagtattt ctggattaga aacattagct
    41701 agaaggtcaa ctaacattac attaagagaa gaaattaatc gtatagtggc agaaataaaa
    41761 gtaggttcta ctattgcaga ttcaatgctt tcatcaaaat caaagtttcc aaagttactt
    41821 ggtgctatgg tagctacagg tgaagctaca ggtaaattag atgaagtatt aaaaagtatg
    41881 gcttcatttt atgcaagtga acacagggtt aaacaaaagc ttagaaatgc tgcaacatat
    41941 ccattaatag ttttgatttc ttcatttata atgattttta tatttacaac atttatggtg
    42001 cctaagatga ttaattcaat tacaacagta ggagcaactc ttccacttat aacaagaatt
    42061 gttatggggt ttggtatgtt tatgaagaag ttttggataa tagtactttt agttattata
    42121 ttatttatct atcagtttaa aaaatatcta aaaacgtcag ttggaagggc tcataaagat
    42181 agagttataa ataagatacc tgttttagga aaaggaataa attgtatggt agctacacga
    42241 ttttcaagag cattgtatct atttgtatca acaggatacc cattagttca agggcttgat
    42301 tatattatag atagtgtaaa taacaccatg gcagagaaga ttttagcatc agctaaagat
    42361 ggaataacaa gaggagaagg cttagcagaa aatttagaga gatatacgta ttttgactct
    42421 gtgttggtac agatgatagc tataggggag cagacagggg aattagagaa tataagtaga
    42481 cagatggcag aattttatga gtatgaatcc gagatttatt taaataggat ggcctcaatg
    42541 atagagcctg ttttaataat tgcagttggt attatagttg cgatactggt tgtatcaata
    42601 ttcatgccaa tgcttagtat atatgatgcc atgtaggagg gaaaggacaa atgaacaagg
    42661 tttatgtatc atattatggc gattctattt ccatagttga gggcagatat aaacacgata
    42721 aggataagtt ttatgtaaaa aattttaatg tgttttcaat agaggatatt gcacaagatt
    42781 tttctaagga aaagtatgct ctattgagat acgcattaga aaatgttaag ttaaaatcaa
    42841 gacatgtagt tttttgttta aatacaagag atgtaatttt aaaaccccaa aaacttccta
    42901 atatggacaa aaaggattta gacggattta tgaagctaga gatggacgaa atgatggctt
    42961 tggagtcaga tgaatatgta ttttcgtatg aagtatctag tgaaacacct gataattcag
    43021 atggcgatga atcaagttta aatcttatta ttggagctat acaaaaggaa gaggtaaatg
    43081 caattgtaga gataatgcat gaatttgatt tagtattaga tagaatagat acattatcaa
    43141 cagcttactt aagaatgctt aaaaatttag actacaatga tataatggta accaatataa
    43201 gtgacaatag cacaattata aatatatata agaaagatac tttatttatt agtgataata
    43261 tacctataaa gataactgct aaagatatgg acatgcaatt attaaatgta gtagaagaat
    43321 caaaaggtct tatgaattac tattcgtcaa gaaactttgg taaggttacg gatactatat
    43381 taatattagg aaaaagatat tccaataaat taatttatga aacttttagc tctgcatttt
    43441 caagctatgt ttctcaaggc cttactgaga taatggatat atctgatatg ataactggag
    43501 atatagatga agatgatata aattcaattg tagagctttt aggaagtatg atagaaccta
    43561 aagggaaaag agattttgaa aatataaact ttttaccaat ggatatactt agaaaacaga
    43621 taaaagctaa acaaatgaaa aacatactga aaattgctcc aatagttatt ttgattcttg
    43681 ctatacctta tttatgttta attttttcaa ataatttagc aaataaggaa cttgaaaatg
    43741 ttaatggtga aataagaaat attgaatctg catattatca gattggaaat atagaaaaaa
    43801 tgatacagag taaaagcgaa gaaataaagg tatatgatat gttaattggg aaaaaggtaa
    43861 agtgggaaaa tttattggat gatatagata aaaatactcc aagtaaagtt gaactaacaa
    43921 gtttatcaac aacttatcaa aatcttggaa ctaataataa agctgataat tcaaaaagta
    43981 ataagactac aacagataaa tcaagtaaca atgaaacaaa atcaagtacg aaaagtgata
    44041 gtaatggaga taaaacagat aatgatttaa atgaagataa gactacaaat gtgtcagaag
    44101 cattaactgg aaatagtgag actaatagta ataacacaga taaagatgat aaaactccat
    44161 tgtatgataa gataccaaat gttataaata tagaaggaaa tgctaaagat tcctcttatg
    44221 taggtcaatt tttatataaa ttaaagggat tatactattt caaggatgtt aaattacata
    44281 gcataaaaag taatgcagaa gattctaact atacatttag tatgacatta tacctgaaag
    44341 aaggtgtatt aactaatgaa taaagatata tttaaaaaag atataaaaga tatatttaaa
    44401 atggaagtta gtctaaaagg gattcttata aaggttataa ttttattagc tattttatca
    44461 tatggttatt ttggacttta ccctcaatat cagaaatata ttgctacaaa aaattctgta
    44521 aaacaggcta ctgaaaaatt aaatatatat aaagagaaaa ctgcacttat gccaaaatat
    44581 gaaaaacaac ttgaagaagt tgaaagtgaa ttaaaagaaa aaagcaaaaa tcttttatat
    44641 gatatgcaag atggtctttt tttaataggt ttagataaaa aaatgaaggc ttataatatt
    44701 gacttaacca gttatgacgt tggaaatgtt aaagaatacg aacattttta tggtatatca
    44761 acaacaataa gtgttagagg tgattataga aatgtcaaaa aattaatggc ttatttagaa
    44821 gaacaaaaaa atgttactca aatactagat tatacaatga cttcatatat agaaccagaa
    44881 aaagaagagg aagaaacaac aaacaataag gatttaatta aaaatgtgaa cataaataaa
    44941 gatacaaaaa tatactgggt ggaaggcgaa aataagtggc atttatataa ggattgtcca
    45001 ttgataaaag agggagagat tctaaaaaat gacaaacttt tagataggtc tactaattat
    45061 ctatgtaata cttgtgtact tagagctgca acagaaaaag aagcaaaaaa agaagtcgta
    45121 gctccaaagg cagaaggtgt agtagatgct acatttaaat ttataatgta cactaaagag
    45181 aatactacaa tgatacttga tacagataat ccatcttcat ggagaccagg aaaatataat
    45241 ccatttaagt ctagtgcgaa ataaagctaa gtaagcttta aagataggtg atgagtttgt
    45301 acaaaaataa tgaaaaaggt cttactttat tagaagtaat aatagctgtt tttatactga
    45361 caatagtttt aagtatttct tataaagtgt tcaatggtat aacatcagca gtaaaaaagc
    45421 aacagattat tacagatgct caagtaaata ttaatctaat taataagtat ctaaatagag
    45481 atttggaaaa ctgtaaagaa ctaactaaaa ctggttcagg taataattat gaatacaata
    45541 tagagatgcc agataatgtt gtaaaatatg aagtttctat agaaactaaa aaaaatacag
    45601 aggtatattc tgtaacgaga atccaaaaca atacaattga tacagaaaat gaagttagag
    45661 aagagataat ctataatcaa ccactagttc aaaacaataa agaaatgaag gaaacaccat
    45721 ttaaaataga aaagcaaact ggtaaatcta tttatactgt aagtatatac tataatgaat
    45781 cagtgcaaga aagtcataaa aatagcaatt taaataacaa aacttataca tttgatgtta
    45841 tgtcaagaat aggataataa gaatttatta aaaaataagt aggttgataa aatatgagta
    45901 aaaagaatag tgaaagagga ttttccttaa ttgaagtgtt agtagctatg gctattatgg
    45961 gaattgtact atttgcattt tttaatatta tcaatactaa taacaaagca aacactaaaa
    46021 atgacacaga tataacttcc ttaaactatg tccaaagtga aatagaaaat ctaagagaaa
    46081 agataaaaag tggagaattt gattttgata gtttagataa actagaagat ggaactgtcg
    46141 tatatgaaaa attaatagat aaatcaaaaa aagttgtata tgataaagtt cttagtgaag
    46201 gtgatgtgag cttatatgat actccatatg aaaagattac aacaataaaa gatgaagatg
    46261 gtaatttaat cgacaaagga aatattacaa ataagataaa gactattgta gaagataaaa
    46321 gtggtcagat atataaaata gctgtaactg ggaaaagcat gaatgactat tcaagtaaaa
    46381 aagaggttaa aattgtaact gaaatattta aagataaata attttacttg ggggtgagat
    46441 tttgaggaag tggaataaat ttaaaagtga aagaggggca gctttagttt tagttttggt
    46501 tgtagtagca ttgctttcta ttgttggatt gatattttca aatcagatag ctaatagaat
    46561 aaaatctaca aagactacta atgaaggtat acaagcaaag tatttagcag agacatgtgt
    46621 ggaaaatagt attgataaag catatgaaaa attgtatgat gagcttgaga aaatggataa
    46681 tgagtttaaa agtgaaaatc aagaaaaatc catatctagg tcaaaattaa gagatatatc
    46741 agatgaagat tttaataatc aagatgagga aaatattgaa gcagaaagac ttggatatat
    46801 gaataatata aatttctatt taaataaagc ttcttcagac ttggaaaaag ctagtatgga
    46861 attgaaaaag ctatatgatt tagatatgtt ggactataga gacattgaat atgtagatgc
    46921 aaatattatt tcacatagag attctatctt agaaatttgc aagaattata cttctggaga
    46981 tattagtaaa ataaatgaat atattctgaa agaagatata gactcaacta cattgattga
    47041 ggcaaagtta gtgaataatg atattctttt aaaaatgttt ttagaagaaa ataaaattga
    47101 aaatgaacat ttaaattcag ccttttcaca tacttataag gcattagata acatttcttt
    47161 ggcgatgcaa aatatgattg agtatagaca tacgtttcat atagatgagc caaaagtaga
    47221 agtatctaat gggattccag attctcaaca atattatgaa ctaatacaaa atcctataat
    47281 aaatagtatg gagtatatct ggaatagtaa atgggataca ttagaaaaac tattggaaat
    47341 tttaccaaat caaactcaag gatttaattc tttaagagtt catttgagaa ataatgtaag
    47401 aaaatttgag aagttaagcg ataatatatc tagtggtaaa aaaaatacag caaaaaattt
    47461 cttaaagtat aaagagttat tgtatgaaat atcagaccaa tgtaatcaac taaaaagtat
    47521 gtcttatgag aaaatacctg ttaaatatga taacatggct ttgataacaa cttttgacta
    47581 tatacaaaat gagcttttag cagagataaa atgcagatta aaagaattaa aaccacaaga
    47641 aattgataaa acagaaggta ttactataaa aatacctttt tataaggctg actacgacat
    47701 gacaaaagaa ggatggccta aattaaaaga aaatggttca ggggcggagt taagcttaat
    47761 ggtaactggt gataaagatg gaataaaaga agtagaagtt acagatggta aaaaaaatat
    47821 tattggttta ggtgttgaag aaaattcaaa ttcaaagtat aaggttgacg ccattgtaaa
    47881 ctttaatcta aatatagata caaatgtagt tggaaattat gatataaaag ataaaatttt
    47941 gattaatcat gatataagtt catacaaaaa agtaaactaa atataagaag caacttagta
    48001 taaataaata ataaaataat tttattattt actactaaaa aaataagtaa actaatagaa
    48061 gatatggaga gtaaatatta tgtatattta tgatttatta gagcaaggta taagactaaa
    48121 cgcatcagat atacacataa cagttggaac aaatcctgta gctagagtaa aaggtggatt
    48181 tgtaaaacta agtgaacaaa tattgacatc agaagtaaca atgcaaatgg caaaagacat
    48241 agcaggggaa tctatgttta aagtaataga agaacatgga gaagctgatt tttcagcttc
    48301 tttaaaaaca ggagaaagat ttagggtaaa tgcatatagg caaaaaggaa attacgcaat
    48361 agcaataagg actataacag cagaaattcc aacatttgaa aaattaggcc ttccagagag
    48421 tataaaatct tttactgaaa agcataaagg attagtttta gttacaggtc caacaggaag
    48481 tggtaaaagt acaacacttg caagtatgat aaatataata aatgaaaaac aacaaaaaca
    48541 tataattaca cttgaagacc cgatagaata tgtacatcat cataaacaaa gtttagtaaa
    48601 tcaaagagaa gtaggaactg atacagaaag ttttcattca gcccttagag ctattttgcg
    48661 tcaggaccca gatgtaatac taataggaga gatgagagac cctgaaactg tttcaatagc
    48721 attaacagca gcagaaacag gtcatttagt attttcaaca ctacatacag tgggggcagc
    48781 taagacaatt gatagaatag tagacatgtt tcaaccatcc caacagcaac aaataaaaac
    48841 acagttatct acagtttgtg aaggtgtggt atcacagcag ttacttccta cagcagatgg
    48901 gaaaggcaga atagcagcaa ttgaattgat gtttgctact ccagcaataa aaaacctgat
    48961 aagggaaggc aaaacatatc aaattccaaa catgatacaa actggagtta aagtaggtat
    49021 gaaaactatg gaccaagatt taatggaact ttataaaaat ggaaagatta caaaagatat
    49081 ggcacttagt aggtgtactg accaagagtt tatgacaaga atgataggtg gagtaaacta
    49141 caatggatat tataatcgtt aatctatatg tatttatggt gggtatagtg tttggaagtt
    49201 tctttaacgt ctgtattttt aggattccag aaggtatatc tatttctaga cctccttctc
    49261 attgtatgag ttgtaatact agactaaagc caatagactt aataccagtg ttaagctatt
    49321 taatgagtgg cagaaagtgt agatattgtt atgagaaaat ttctagtaga tatgctatag
    49381 tggaattaat tacaggactt ttatttttaa cagtatttat gttatatgga atatctacat
    49441 caactattta ttatttggtt cttgtgtctt tactgattat aattacattt atagatattg
    49501 accactttat aataccagat aaaatattgg tttttggagc tatattttct atgattttta
    49561 accttttatt taaagaaatt ccagttaagg attcaattct aggtgttttt atttgtggag
    49621 gaagtgtctg gattatagtt cttttgattg aatttgtaat aaaaaaagag tgtatgggtg
    49681 gaggagatat caaactattt gcaatgctag gtttttacat gggtgttaaa aatggtcttt
    49741 tgacagcctt actaagcgtt tatgtgggag cagtctatgg aatctgtgta ataattataa
    49801 gtagaataaa aggaaaggaa tataattctg ttataccata tggacctttt atatctattg
    49861 gagcattaat aacaatctta tgtggaaagc aattacttga actttatttt tctatggtta
    49921 tatagatgat agtcaagtta aataaagttt taatttaaaa aaatgaatta aagtatttaa
    49981 taaggacaat attattatta accctattac taaagtgcta caaactatgg agtatataat
    50041 aataatttcc ttattttttg cacatttgat aaataaatct ctatgtgttt tttgtgatag
    50101 agaaaagaaa aatttataca atacgttttt tatttacata ataactgtag ttttatctgt
    50161 attaatatat ctaaaatttg ggattagtgt agaatgtgta caatatatgg ttttaattcc
    50221 atttttaata attatatcca ttgtagatta ctacacaata tatgtatatg atataacaat
    50281 agttagtggt ataatagttc aaggtataat ttttttggtc tttttcaata tagttcaatt
    50341 tgattatata aatcatatat ttggactatt gataggcttt attatacctt atattattgc
    50401 taaactaaca aaaggattag gctatggaga tgtaggtctc tatagcttat gttgctttgc
    50461 attgggaaat aattatgggt tttatgtgat agttttatca tttattttag cgtttttgtt
    50521 ttttattatt ttatacataa ctaaaatatt taaagatgta gatataagaa agcaaattcc
    50581 ttttacacct tttatttcct tgtcaacaat tttaataata tttacagagt ataatatatt
    50641 taatttttat tataatttgt tatacaaatt tatataacag gaggtaagaa atgtacgtag
    50701 tagtagggtt aggtaatcca ggaaagaagt atgagaagac tagacataac gttggatttg
    50761 atgttataga tattcttgct aaagaataca atattagtgt tactaaaata aagcataaag
    50821 ctttgattgg tgaagggaga gtaggtactg aaaaagtatt attagttaaa ccacaaactt
    50881 atatgaattt aagtggagaa acattaatag atatatataa atattataag gttgatttaa
    50941 gtaatatagt agtagtatat gatgatatag atttagaagt tggaaagata cgtataagaa
    51001 aaaaaggaag tggaggaact cataatggca tgaaatctat aactaagtgc ctaggttcaa
    51061 atgactttcc aagagtgaga gtaggtgtat ctaaaccaga agctggtcaa gacttagcag
    51121 actttgtact ttctagattt agaaaagaag aatctgataa cataaatgaa gcattagaaa
    51181 aagcggcaga tgctattgac tcaataataa gagaaaatat agatatgtct atgaacaaat
    51241 ataatggata gtgagaggga gatttaaatg aatgatgttt ttttatatcc tttgcaaaat
    51301 tcaaaagagt ataaagatat aataaactgt ataaaaaata caaaaggctc attattggtt
    51361 aatggacttt taccagtaca aaaacctcat atatcgtatt ctatatttaa tgatttatca
    51421 cgacaaatga tttttataac aagtagtgat ttagaagcaa agaaagtata cgaagattta
    51481 agtttttata tggaagataa agttgaatat ttaggttttc aagatattta tttttatcac
    51541 ttggatgcaa aggacagaaa cgaagaagcg aagaaattaa aagtattgtt aaaactagca
    51601 aataaagaaa aaatcatttt agtaacttct attgaggcag ttttaagaaa atacatacca
    51661 aaacaagttt tgctcgatag tgtatctcat tataaggtgg gagatagctt agacttagaa
    51721 aagttaactg agaaattagt ttcattggga tatgaaagag tttcaaaaat agaggggttt
    51781 ggtcaattta gtataagagg tggaattatt gatgtatttt cacttgaata tacaaatcca
    51841 attcgtatgg aattatttga tgatgagata gattccatac gaacttttga cgtatattca
    51901 caaaaatcaa ttgataaatt gcaacaattc tctataactc catctaggga atttatttat
    51961 cccgaaaaaa ctacagatgc attagttaaa ttaaaaaaag aaacaactaa aaatactgat
    52021 gaaggtacat ttcaaaatat agattatata tcaagtaaga cttattttga aggtgtagag
    52081 aactatatag attatattta tccagaagaa aacaaaagta tatttactta tttagcagat
    52141 gatgcaatag tatttattaa tgatataacg agacttaaag aaagatgcga aaattatata
    52201 aatgagttta gagaaaatta taaattaaat cttgaaagag gtctggctat taaaaaccaa
    52261 ggtaaattgt tatatcacta tacagattta gagtacttag taaaagacaa gtctgtggta
    52321 ttaaactcgc tattgccaaa gtctataaat aacttttcta taaaatctat aataaatttt
    52381 gaaagtagag aagttcctac atttaatgga aaggtagatt tgcttgtaga agaattaaat
    52441 cggctgaaat ataatggata caaaataatt ttagcaacaa ataccttaga aagagcaaat
    52501 aaattaggaa aagatttatt ggacaaaggc ttagaaacga ccatttctaa agatagagat
    52561 attgaaatta aatcttcaca agttataatt gtacctgcac acataaacag tggttttcag
    52621 tataaatcta taaagtttgt tgttataaca gataacgaaa tgataggtgt ttataaaaga
    52681 gcgtctaaga ctagcaataa aaaagttaaa aagggaaaga aaatagaatc ctttttagat
    52741 ttaagtgttg gagattatgt agtccatgaa aatagtggtg taggtagata cacaggaatt
    52801 gaacaaatta cagtcaatgc tattaaaaaa gattatatga aaatagtata tcaaggtgga
    52861 gataatctat atgtgccaat agaccagatg gacaaagtac aaaaatatat tggtgcagaa
    52921 gtagaaaaag ttaagttaaa taagcttgga acaaatgagt ggacgaaagc aaaagcaaaa
    52981 gttaaaaaag aaattgaaga tatgacaaaa gacttgattg agctttatgc aaaacgtgaa
    53041 aaaatacaag ggtataagtt ttcaaaagat acaccttggc aggcagagtt tgaatcgttg
    53101 tttccatatc aagaaacaga agaccaatta aaggctatag aagaaactaa aaaagatatg
    53161 gaatcaagta aggtaatgga taggctagta tgtggagatg ttggttatgg aaaaacagag
    53221 gtagctatta gaagtatttt taaagcttgt atggaccaaa aacaagttgc tgtattggtt
    53281 ccaacaacaa tattggccca acaacattat aatacattca aagagaggtt tgaaaattat
    53341 cctttgagag tagaagtttt aagtaggttt aaaacaccaa aacaacaaaa acagattatt
    53401 gaagatgcta aaaaaggatt agtagatatt ttaattggaa cacatagaat aatatccaaa
    53461 gatataaatt taccaaactt aggtcttgta gtcattgatg aagaacaaag atttggagta
    53521 aaacataaag aagctttaaa gaaaattaaa tctacagtag atgtacttac actttcagca
    53581 actcctatac caagaacatt acatatgtct ttaagtggaa taagagacat gagtgttata
    53641 gaagaacctc cacaagaaag acatcctgta ataacatatg ttacagagag taaggaaagc
    53701 gtaattcaag atgagataga gagagaatta agtagaggtg gacaggtatt ttttgtatac
    53761 aatagagttg aacacattga agaaatggca agtatgattc aaaaactcgt accagatgct
    53821 agagtggctg ttgcacatgg aagaatgact tctaaatcat tagaaaatat aatcctagga
    53881 tttttaaata aagattatga tgtactagtc tgtactacaa taattgaaac tggtatggac
    53941 atatcaaatg caaatacaat gattatatat gatgcagata aaatgggatt ggctcaactt
    54001 taccaattga gaggtagggt tggaagaagt tcaagacaag gatatgcata tcttttgtat
    54061 gaaaaagata aaactttaag tgagatagcg gagaagagat taaaagctat cagagaattt
    54121 acagagtttg gttctggttt taaaatagca atgagagacc ttgaaataag aggagcagga
    54181 aatattttag gttctcaaca acatggtcat atggcagtta taggttatga tttgtacgtt
    54241 aaaatgctta atgatgcaat taaaaaagtc aaaggtgagc ctattgtgga ggaaattgat
    54301 gttgaaatag atttaagtgt aaatgcatac attccagata attatatcaa agatgagttg
    54361 attaaaattg aaatgtataa gaaaatagct tctattgaaa acaaagaaga catgttggat
    54421 atacaagaag aacttgagga tagattctct gatataccta aaccagtcca gacacttctt
    54481 acaatagctt atataaaatc gttatgtaag atattaaaaa tagaaaagat aagacaatta
    54541 aaagatgaaa tattattagt tccaataaca aagtatagaa ctaaacagaa aataggttat
    54601 aatatagtta cagaattaga agaattatta gaaaagatgt gcaaggtaaa ataacttgta
    54661 aatttaagaa gggatgtttt aaatttgaaa aaagtaataa cattggtaat agctatgatt
    54721 ttggtagtat ctgtgactgc ttgcagttct agtaaaggag aaactgtggc aacagttgaa
    54781 ggtacaaaga tatcatcaga tgaatttaaa aaaactatag ctctttataa agattctatg
    54841 gaacaaactt atggaaaaga tatatgggat aaggaagttg aaaagggtgt aaaatacaag
    54901 gacaagttta aagatttaat tcttgaccaa cttataacta cagaagtaat atattctcaa
    54961 gctaaaaaag ataacttact tcctaaaaaa gaggatgttg aaaaaagttt taaagaatta
    55021 aaagacgcta tgggtaaaga tgaaaaatat aaagaacaac ttaagaaatt aggtatagat
    55081 gatgagtttt taagagacca acaagagaaa gatttagcaa tgcaaaacta tcaaagtaac
    55141 tttgctaaaa agactaaaat atcagatgaa gaaatgaaaa aatactatga tacacataaa
    55201 gatgaattta aaaaagatga ggtagaagct tctcatattt tattgaaaac agtagatgat
    55261 aataacaagc cactttcaga taaggaaaaa gctgaagcta agaaaaaggc tgaagaggct
    55321 cttaaagaag ttaaatcagg tgaggatttt gcaaaagtag caaaaaaata ttcacaagat
    55381 acttcagcaa gtgatggtgg taaattagga ttcttttcaa ggggtcaaat ggttgctgaa
    55441 tttgaagatg ctgctttttc tatgaaaaag ggtgaagtat ctgatttagt tgaaactcaa
    55501 tatggatacc acataattaa agtgacagac agaataaatg agcaaacatc atttgaagat
    55561 gctaaagaaa ctataaaaga ccaactgttg aaaaataaat atcaagaaca aatagaaaaa
    55621 ttaactaaag aagctaaggt agaaaaagat gaaaaagtaa taaataaaat cacaatctaa
    55681 gacttaaaaa aagagtaata tgcttaaaaa agctatatct ggataagata tagctttttt
    55741 tgtatatttt tcttaacaat ggtaaaaata aacttaaagt aatttatgga gggattaaaa
    55801 aatatgaaag caacaggtat agttagaaga atagatgatc ttggaagggt agttatccca
    55861 aaagagataa gaaagacatt aagaattaga gaaggagacc ctttagagat attcacagca
    55921 aaagatggag aagtcatact taaaaaatac tctccaatag gtgaattaaa tgaattttcg
    55981 caagaatatg ctgaaacatt agctgaagta ctaggatatg gagtgttgat aacagactta
    56041 gattctataa tagctgtgtc taagcttcct aaaaaagatt ataaagaaaa aagtataagt
    56101 gatgagttag aagcaataat aagtgaaaga acagtaaaat attcaaaaga taaaaacatt
    56161 ttaccattat tcaaggaaga ccaaaaagaa tatactagtc aagttatcat gcctataatt
    56221 agtgcatctg gtgactgtat aggttcaatt gtagttgttt caaaggataa agatacaatt
    56281 gcagaaagtg aagaaaaatc tttaaaaatt gctgctaact ttttaggaaa acaagttcaa
    56341 taattttatc ataaagacct tttacatgaa ggtcttttga agtttttgtg taaaatattg
    56401 aatatagcat taaaaatatg gtatattaaa gtttgttata taaacagtat ggaggttatg
    56461 ttatgaacaa taacaaaaat aaagactcct ttctaaaagg agcccttata cttgggctag
    56521 caggtgtaat cgtaaaaata atgggtggat tttttaggat tccccttgga aacatgattg
    56581 gttcagaagg aatgggatac tatcaggctg cttatcctgt gtatactcta tttttaacat
    56641 tagctactgc tggatttcca acagctgtgg caaaattggt ttcggaaaaa gttgcaattg
    56701 gaaattttaa aggtgcaaat aagatattta aggtatcaca tacagtttta ttcattaccg
    56761 gtataatatc attttgtata ttattttttg gagccgacta catagtaaca aacgtaatga
    56821 aaaatccagg tgcgttatac tctatgaaag ccattgctcc agcattacta tttgttcctg
    56881 caatgtctgc atatagagga tattttcaag ggagacaaga tatgactaag attgctgtgt
    56941 ctcaagttgc agagcaattt tttagagttg tattaggtct tactttggct tacttgctta
    57001 tgaagagtct aggtcagact tttggtgcag caggtgctat atcaggggct acaataggtt
    57061 caatagcatc tatgctttat ttggtgtttg cttatatgct agggagaaaa gagcgtagag
    57121 cagagataga tgcaagccaa agatttaaag atgaaagagt gtcttatatt tttaaaaagc
    57181 ttttaactgt tgccattcct ataacaatag gagcatcagt aatgccactt gtaaatatga
    57241 tagataatgt tattgtaata agaagactta tggaagcagg ctttacatac aaagtggcaa
    57301 attccatgtt tggtcaatta acaggtatgg caatggccac aataaattta ccagcagtca
    57361 taacaactgc aatgagtatg agcttagttc cagcaatttc taaagcatat gcattaggaa
    57421 ataagtcaaa agctagaaaa gatactaaga gtgcagttaa ggtaacttta cttatagtat
    57481 tgccttgtgc gtttggtatg gcttctttag caataccaat aatgggtctt ttatttccac
    57541 atgaaccatc ttctgtagga actattttgt ttactcttac tccatgtgta ttatttttag
    57601 gattaataca gacattgact ggtataattc agggaatggg aaaaccaata gtacctgtaa
    57661 ttgctttatg tgttggtatg ctatgtaaaa ttgtaataag ttatacttta acaggtatac
    57721 cagatattaa tgtactgggt tcagcatttg gtacagttac agcatacttt gtggcagcca
    57781 tgattaactt actatatgtt aaaaaacaca tgaatgtaaa cttttctaaa aaagaattta
    57841 taataaagcc atttataaca gttatgacaa tgtttataat ggttaagttg agttatggtg
    57901 ctttagttgg attcttagga aacagcatat ctacaataat tgcaatatgt gttggtggaa
    57961 ttgtatatgt agtagtaata cttggaatag gtggaattaa aaaagaagag attctaacta
    58021 tgccaaaagg tgataaatta tataaattgt taaaaaaagt taaacttata agataatata
    58081 ggaatatata tgcaaataaa ggaaatacta tacaaatagt aaatctcctt atttgtataa
    58141 taatataaaa ataaagtgaa atttgctaat aggagtgatg ttatgggtaa gataagtatt
    58201 gtaggtcttg gaccaggaga ctattctctt ataagccaag gtgtgttaga atctttaata
    58261 aatagcccta aagttttttt tagaacagag aaacatccaa taattgataa acttaaagaa
    58321 actatacaat acacttcttt agactacttt tatgaaaaag aggaaaattt tgataatgtt
    58381 tatttgaaaa tatctgaatt tatcatagaa gaatcagcaa agggtgacct agtgtatgct
    58441 gttcctggtc atccaagagt tgcagagaag actgtaagta taatagagag attagccaat
    58501 gaaaagcaca tagcagtaga aatattgcct tctatgagct ttgtagacgc tatgtttaac
    58561 tatttggcta tagacccatc tgagggattt aaactggtag atgcttttga aatagaaaat
    58621 tcatatatag acttggatac aagtatgata ataactcagg tatatgataa atttatagca
    58681 tctaatgtaa agttaaaact tatggaacat tatgactata atcaagaagt atgtatagta
    58741 aatggagctg gtgtcaaaga tttagaaagt aaaaagttta taaagctttg tgaattagac
    58801 agaaatgaaa acttttttga ctatttaact agcttatata tacccaaaag ttctaaaaag
    58861 atgtataata cagtacatga cttagaaata atagttaata cacttagaag tccatctgga
    58921 tgtgaatggg ataaaaaaca aacacatcaa tcattaaaaa attctgttat agaggaagca
    58981 tatgaacttt gtaatgcaat tgataataat gatatagatg aaatggtaga agagttaggt
    59041 gatgttcttt tacaggttat attccattgt cagataggaa atgaggaggg ctactttgat
    59101 ttaaaagaag tagtaaatgg catatgtaaa aaattaattc atagacatcc tcatatattt
    59161 agtggtgcaa aattagatat gtctaagttt gagaaaactt gggaagaatt aaagaaagaa
    59221 gagaaaggcg aaagtactat aacagatggc cttagaagga taccaaaaca tttaccagct
    59281 cttatgaagg ctagtaaagt tcaacataaa gcagcacttg tcggctttga ttgggacaat
    59341 gtagaagatg tatttaaaaa aattgaagaa gaatatcagg aattacttga cgaacacagg
    59401 gtcgggaata taaaatacat aaaggaagag ctaggcgatt tattattttc gatagtaaat
    59461 ctagctagat ttttagacat agactcagga gaagccttga actgtactac agaaaaattc
    59521 ataaatagat ttgactttat agaaaagagt gcaatgaact tgaataaaaa attagaagac
    59581 atgacacttg aagagatgga tgagttttgg aatcaggcta aaaaacaata aaattgtgga
    59641 aggaaatttg tcaaaaatct agaactttta tcacaaagat agaagtctat attataaaca
    59701 tttttaggag gtaaatatcg tgaataaagc tgaattagta tcaaagatgg cagaaaaaag
    59761 tggattaaca aagaaggaag cagaagctgc gttaaacgca tttatgagtt ctgttcaaga
    59821 tgcactagta aataatgaaa aagttcaatt agttggattt ggaacatttg agacaagaga
    59881 aagagctgct agacaaggaa gaaatccaag agatccagag caagttatag atataccagc
    59941 ttctaaagca ccagttttca aagctggaaa aggattaaag gatataataa atggataatt
    60001 agaaatcttg tgaaaaagtg tggataaatt tgccacactt tttctataga accaaggaag
    60061 gtgataatta tgagattaga taaattttta aaagtatcta ggattataaa aagaagaact
    60121 gttgctaaag atgcatgtga taaagggatt gtcactataa atggaaaagt tgctaaatct
    60181 tcttcagagg tgaatattgg agatacatta gaaatacaat ttggagagaa gaagatgaag
    60241 tttaagataa atgaagtaaa agagcatgta ttaaaaaatg atgcaaaaga aatgtacgaa
    60301 attttagaat aaaattaata gtcctctagt atattaatag tagtattatt gaaatattta
    60361 ctggggggat attatggaac agaacataac tttgaaagat agatcaaagc tggttatttc
    60421 gggagtcgag cacatatact cttttaatga caaaagagta gagctcaaaa cttctgtagg
    60481 cgagatggta attgaaggcg aaaacctaga tatgagcaag ctaagtatag acgaaaatat
    60541 aattagcata gatggaacta taaattctat ggtatatgca aagcctaaaa agccacaaga
    60601 gagtttcttg aaaaaggtat ttagatagat gatacctttt actcaagatg taagcatttt
    60661 ttatgctact atttatggtg gaatactcat aggggtgttg tttgattttt atagagggct
    60721 aagagggaat tttaaattca tcaattattt tgctataata tttgatgtat tgttttggtt
    60781 tctagctacg gttataatat tcgtaacaat aaaccttaca gaattttttg atttaagata
    60841 ttatcatttt gtggctttgt ttattggttt tattttatac tataacacca taagtaaaat
    60901 tgttttatca attatcaata aaataattcg ttttgtgaga aattctttta aaaaagttac
    60961 acattacata gtcagttttt taaataattt gtattacgtt ataatctatt cactacacct
    61021 actatttgat attatatttt atataccaaa catatttata gcaacaagaa aaagtataaa
    61081 aagaaaatca aataaaaaat taaagaacaa gaaaaaatca aaacctaaga agaaaaaaaa
    61141 taaaactaaa aaaagggtgt aggaaaaatg aacttaagaa aaaaattttc aggacagatt
    61201 attgttatca gtttattttt aggaatatca atttttagta tgatgacagg atttgtattt
    61261 gagtatacaa aagctaagga atataaaaaa gaaatagcaa gtctaaataa acaattaaaa
    61321 aagactgaaa tacaaataaa cagcttaaag aaagatgaaa aatcatatga aggagactta
    61381 gaggatatag caagaaaaag attgaatatg gtaaaaccaa atgaaacagt ttatgtagac
    61441 ataaatcgtt gattaaaact tgctaataag tttacagatg tattgatttt aaaatttaag
    61501 atttaataaa aaagtcattc agttaaggat ggctttttgt ttttattgag gagggaattt
    61561 cataatgaaa gtaggagcta tagatattgg gacaaactca atgagattat tgatagcaga
    61621 ttatagagat gggaatttta taaacagaaa aaaatttgtt aatacaacta gaattggtta
    61681 tggtgtggat agtaaaggat atataaaaga agatgctatc aaaagaaata taaaagcatt
    61741 aaaagaattt tctgataagt gtaatgatga aaagtgtgaa aaaatttatt gtatggggac
    61801 atctgctctt agagacagta aaaatggaga ttactttgtt aaattagcta aagaagaaac
    61861 tggaatagat gttgatatag ttacgggaat agaagaatca aatttgggct ttaagggtgt
    61921 tttagaagga atacaaggtg atgatactat tattgttata gatattggag gaggttcaac
    61981 agaatttatt gtaggtgatt cagaaggaat tatatttaat aaaagtgaga atgtaggtgc
    62041 tcttaggatg acagagaggt ttttgaagca cgatattatt gaagatgaag agtttgaagc
    62101 tatgagttca tttatatatg gtgagattga taaaacgtta aatcatataa aagacaaagg
    62161 attaaaaact cttataggta taggaggtac gattacatca ttatcagcaa tgaatcaaga
    62221 attagagatt tactctatgg aaaaaataca taatagtaaa atacacaaaa aagaaataga
    62281 agaaattcta caaaaattaa taaagatgac attaagtgat aaaaagaact taaaagggct
    62341 acaagaaaaa cgtgcggata ttataactgc tggtgtaaaa atattgaata taataatgga
    62401 aaaattagaa atagaagaaa taaccgtaag tgaatacgat aatttggaag gcttaatatg
    62461 tcaaaagtca aaaaaaatgt attaatattt tttgattttt aaaaccgatt atgacaaaaa
    62521 aaattactcc tctttgttac aattcttaat ataaacaaaa gaggaggttt ttttatgcaa
    62581 agaagtgtag cagttgtgaa gaataagact gtaaaaccaa atgtcataaa attaataagc
    62641 ggatatattg attttactac ggcggcattc gctgtgatgg gatttttact tagtaggtct
    62701 attatagtag actctgtagc tcctttagga attgcctttt ttatatgtgc atcaaagatt
    62761 gataagtaca agatacctgt attcatatca acattattag gaatattgtt atcatctaat
    62821 gattttggaa atgtagcaaa atatgctgtg tgccttacaa tatttatggc tatgaataaa
    62881 aaattaaaat tatcagattc aattgctaag gttgcattta taggtgcaat aatactactt
    62941 ccaatctcca tgggacaagc tttcttttca aataggtatg tatatggtct tcttatagca
    63001 ggagtagaag caataataat gtttatatct atatatgtgt tttcttatgg gataggttta
    63061 atggccaatg tcaacaatag gatgtctgta cggacagaag aagccatatc aataagttta
    63121 ctgctaacct ttagcataat gggaatagga gatatatctc tgtttggaat atcaataagg
    63181 accattttat cgaccgtatt gatattgctg acctcaatag taggtggagc tactatggga
    63241 gcatctagtg gtgtaattat tggtgtagca tccattttaa ataatatgac atcagctgtt
    63301 tatatgggga tatattcttt ttcaggatta ataagtggag catttaataa aataaataaa
    63361 tatttctgta tactaggata tattctaagt tggacaataa tatacctata tacttctggt
    63421 attacttcta atatgatgca attaagagat atactattag gttgtttgat agtactagta
    63481 ttgccagagc gattatttaa taagattgaa aaattaataa aaagtaatgt ggcttcaaat
    63541 gaaatcgtat acgattatat tatgagaagc aaaaacctaa ctaatagcag attgaacagt
    63601 atttataaaa cttatgatga ccttgcagat acatttgata agataagaga aaaagacaaa
    63661 gtgctagacc aaagagacat agctaatgta atagatatga ttcataatga tgaatgtaaa
    63721 agttgtagta tgagaagaat gtgctgggag tcaagattta atcatacata cactatgata
    63781 tataacattc ttgaaaaaat tgaggagaaa ggggagttaa gtctaaacga tatacctaaa
    63841 aattttagaa aggaatgtat gaaaccagag tcaatagtga aaatatcaaa tcactattac
    63901 aaaatgtttg tattagatta tgattggagt gtgaagtttt cagaaagtag aaagttaata
    63961 gcaaatcaga taagaagtat ttcaaaatcc attaaatcct tatctcaaga tttagaaggc
    64021 gacataatgc tagatataga aaaggaaaaa aatatatatg aacagttaga aagatatgat
    64081 ataacagttg ataaagtaag ttacttaaca aaaagtaaca gtgagtttga aatatcaata
    64141 gaaaagaaaa cttgccatga tggatgtatg tgtgaagata aaattgtaaa tataatttca
    64201 gacctagtag gggaaaatat gtctgttaga aaaataggat gtcactgttt aggaggtaaa
    64261 tgcaaggcaa cattcgttaa atctcaaaaa tataaggctg ttacagaagt ttcagcaatg
    64321 tcaagggatg ggcatatcct ttgtggagac aattacacat acatggagat aaatgatggt
    64381 aaatacatga tggctataag tgatggtatg ggaaaaggta aaaaagcata tgaagaatct
    64441 tctgccacta ttgatatact ggaaaaaatg atagatgcaa aaattaaaga tgagatagtc
    64501 attgatacta taaataatat gttgttgtta aagtcttcag aagagatgtt ttcaactctg
    64561 gatttgggaa ttttagattt aaaacgaggt tgtttagaaa ctataaagat gggagcgtgt
    64621 tctacttata taaaaagaga ggatggagaa gttgacttaa tatcgtcatc atcattacct
    64681 gtgggtatat tatcagatgt aaaaattgat agaaaaaatg taaaagttaa ggaaggagac
    64741 tatgttataa tggtttctga tggaattgta gatgcaggaa gaaataacaa tttaggagac
    64801 aattggttaa tatacttctt aaagaatata gagactacaa atccaaagga aatttcaaat
    64861 ttaatattgg atagagcatt agagttacaa gcgttacaaa ttgaagatga catgactgtt
    64921 ttagttacga aaatatgtac aaaataaggt ttacaagatt atgtgtataa gatgtggata
    64981 acttgtgtat aatatgttaa tagacttttg aaaaaagtat agttattaac aaaaataaca
    65041 tataaatcaa caaaatttgt tgataagtat ggcagaaatg ttaataaaat gtaaaaaaag
    65101 aaaaaacaaa agctattatc aaaagagatt catgttgaaa taactaaatt tctaagtaaa
    65161 gaaaacctgt gaatatgttg attattatgt ggataactat taattcgata tttatttata
    65221 tagtatgaat aattgaataa tatatctaaa aaaagccatc ctattattaa gtaaacttat
    65281 tgaaaggatg gctttttatg aatagaaaat tgtgcaaagc aataatacct ttatttattt
    65341 ctattttttg catgttaata ataagtataa aagctgacca aggatatcaa aagaataatg
    65401 atagagcaat tactgtcatg aataataatg atactgaaga tgatgctgaa aaaaaacaag
    65461 aaatagacta tgaaaaaaca tgttggaatt tgcaatcttt gtttaaaagt gatgaccaat
    65521 ggaaaaaaga acttaagagt tttgataaag atactaaaga gttgaaaaat tacataggta
    65581 aagtaacaaa atcgccaaca catttgtctt ttgccttaaa cattaaagaa aaacttgata
    65641 taagactaaa taaactttct gcctatgtaa aattaaaaca agatactaat aaaaattcgt
    65701 ataagtactt agatatgaat gatagtatga gtaaatccta tgggaattat atggggattt
    65761 gttcagattt agagttagaa atactaaaat tatcaaacaa agattacaag aaaattattt
    65821 caaataaaaa tataaatagg aaatatggtg catatttaag agatataaga aggaataaag
    65881 tacattattt ggatgataaa tcagaagata ttctaagcaa agtatcttca ataagtagtc
    65941 ttccaagcca agtatatgaa ttatttagaa atatggatag aaaaactaat ttgacaccag
    66001 ctcaatatgc gagtgaatta gagtcatcag atagagaaaa tagaaaaaaa gcttatcaag
    66061 atgaacttat aacttacaat gataatataa atacaattgc aggtttaatt actggtcaag
    66121 ttaaaaagaa tattttttat tctcaggaaa gaggttatga gtcttcttta gaaatgtacc
    66181 tggaatctga taatgtagat gaaaaagtat acaataattt gataaggact gtaaatagta
    66241 atatggacag tctacacaaa tatatagatt taagaaaaaa agtattaaaa ttagataagg
    66301 ttcattcata tgatatgttt gtgcctatgg ttaaggctgt tgataataat attaattatg
    66361 aaaaggcaca aagtatagta tattcagcgt tgtcaccttt aggaaaagaa tacaatgatg
    66421 tagtatataa agctttcaat gaaaaatgga tagatgttta ttcacatgaa aataaagtaa
    66481 gtggtggata ctgcttatct gtttatgaaa atcatccata tatactttta aattataata
    66541 attcattagg ttcagtttcg actttatcac atgagcttgg acatgctgta tatgaatatt
    66601 taagttctaa gaatcagaat tattttaatt caaatccgtc tatatttact cacgaagttg
    66661 catctacaac gaatgaagca ttactttacg agatgcttat aaaagaagct aaaggcaatg
    66721 atgaaaaagc ttattatata acacagtatt tagacttgat aaaagatact ctttatacac
    66781 aaactatgta tgctgaattt gaaaaaacta tacacgagtt agtagaaaaa ggaaaaagtg
    66841 taaacgcatt agtattaaat gatgtttggg gacaacttct taaaaaatat tatggacaaa
    66901 gctatgaatt agaccaatta tctaaggtcg gatgggctag aatcccacat ttttataata
    66961 gtttctatgt ctataaatat gctacaggtt gtagtgcagg agtaagtttt gcccaagaca
    67021 tcctaaagaa tggttcagat aactatatga gctttcttaa aaagggaagt tcagattatc
    67081 caataaactt gttaaaatca agtggcataa atttaactaa tacaaaaccc atagaaaata
    67141 caatcaaaaa atttgatagt ttagtagcag aacttgaaaa gctattataa acattattgt
    67201 aattcacatg gtaaatatat cgaattaatg ataaaatata ctaaaagttt aaagtcctat
    67261 caagatagga ctttttattt attaattagt gggagatgat tctatgcaag ttaaagttaa
    67321 aaaggctgta ataccagcag caggtttagg aactagattt ttgccagcta caaaggcaca
    67381 accaaaagag atgttaccaa tagttgataa gccaactcta caatacataa tagaagaagc
    67441 tgtggcctca ggaatagagg aaatactaat aataacaggt agaaataaaa aatctattga
    67501 agaccacttt gataaatctg tagaattgga acttgattta gagaaaaaag gtaagaaaga
    67561 attgttggag gtagtacaaa acatatctaa catgattaac atacattata taagacaaaa
    67621 agagccaaaa gggttgggag atgcaattta ttgtgcgagg cattttatag gtgatgagcc
    67681 gtttgcagta atgttagggg atgatattgt agataatgat gtaccttgtc taaaacaact
    67741 aacagatgca tatgaggaat atagaactac aatattgggt gttcaaaagg taaatcaaga
    67801 agatactaat aaatatggga taatagaagc aaaaaatata gaaggtagag tttacaaggt
    67861 aaaagacatg gtagaaaagc cagagtcagg aaaagctcct tcaaatattg ctattttagg
    67921 tagatatata ataactcctg aaatctttga tattcttaag gatttaccac caggtaaagg
    67981 tggagaggta caacttacag atgctttaaa aatattatct aagaaagaag ctatgtatgc
    68041 atacaatttt gaaggcaaga gatatgatgt tggggacaag ctaggatttt tagaagctac
    68101 tgttgacttt gctctaaaga aagaagacct taaggaagat tttataaaat atttgaaaca
    68161 tgtatgtagt gaatttgata aaaataacaa tgtgttatac aataatacag atgaaaaaat
    68221 agatttaatt gaagtcaatg aagctagaga acttgaaatt caaaaataat taatgaaagg
    68281 tgatgtatgg tggcaaaatc aagtcagaaa agaattaata gaataatagc tgttgggatt
    68341 gtgggaatcc tcgtaataac gagtataaca gctgttttga gtatgattgc aactatgtaa
    68401 taagataaat gacagcagtt gatatacata aatataaaaa ccatatataa cttgatgtag
    68461 tcaaaaactt acaatatttt agttatatat ggtttttaga atttataaat gtaaaaaaaa
    68521 atttttataa tagttgcata ttttaaagga aaatattatt ataagatata aatatagtga
    68581 taaatttata aaaacgtgct aagattggac ttgaaataca gtaatatagt aggtaataat
    68641 gttttaaatt ttatttattg accataatat ataaataatg atattattag acttaactgt
    68701 ttaaataaaa cttttctttt tcatgccttc aatttccaaa ataagtatgt atataaatga
    68761 atatatagat gaggaggatt tttttgattt tagatgataa agtattagaa ggattaggta
    68821 gtaagacctt agttgagcta cgagagatag ctaaagaatt aaaaataaaa tcaattacta
    68881 catataagaa aaatgagtta attgagatta taaattccaa aagtaaaaat gaggaaaaag
    68941 taaacgaaga gactaaagaa aaaaatgaag atattaaaga agacataaag aatagaaaag
    69001 aaaatataga gcgtgaaagt atagaaaaag aagttgaata taagagccct accaaatcat
    69061 acaacaagaa agaaatagat acccaaaata tttcccaaaa ccaagaacat agaaatcaaa
    69121 gaaatgacta taataagaca acgagtgtaa atgatagtaa taagtcatca aatatatcta
    69181 atagaatggt cagaaataat aataaaaact attatatgcc taaacaagtt gatgaatcta
    69241 agatagtaga tgaatttaac acatcaaaag aggatgaagt agtaggtgta cttgaaattc
    69301 tgccagatgg atttggtttt ttaagaggtt caaattattt gtctactgaa ggagatgttt
    69361 acgtttcacc atctcaaata agaagattta atatgaaaac aggagacaag attaagggaa
    69421 taactagaca tccaaaaagt ggagagaaat ttagagcact tttatatgtt caaaaaataa
    69481 atgatgaaaa ccctgacaca gctatacaaa gaaatgcgtt tgagacatta acaccaatat
    69541 ttccagaaga acgacttaca ctggaaacta atagaaatga aatagctaca agaattatag
    69601 atttaatttc acctatagga aaaggacaaa gaggattgat agtagcacct ccaaaagctg
    69661 ggaaaacagt tcttttaaaa agcgttgcaa atagcatagc taaaaatcat ccaaatgttg
    69721 aacttatagt actccttata gatgaaagac cagaggaagt tactgatatg aaagaatcta
    69781 ttgaaggaga cgttatatat tccacttttg accaagtatc aagtcatcat gtcaaggttg
    69841 cagagatggt gttaaataga gctcaaagat tagttgaaca tggtaaagat gtagtaattt
    69901 tactagatag tataaccaga ttggcaaggg catataacct tacaatatct cctacaggta
    69961 gaactttatc tggaggtatt gaccctggtg cacttcatgg acctaaaaag ttctttggtg
    70021 cagcaaggaa tattagacag ggtggttctt tgacaatatt aggaacagca ttggttgaaa
    70081 ctggttctag gatggatgat gtaatatttg aggaatttaa aggtacagga aatatggagc
    70141 tacatttaga tagaaaatta gcagaaaaaa gaatattccc tgcaatagat atttacaagt
    70201 ctggtacaag aagagatgat ttattgcttg atgatgaaga aaagactgct ctttggagat
    70261 taagaagaga aatgagtaat aattcagtaa tggaaattac agataaagtc attgaactta
    70321 taaagagaac taaggacaat aaagagtttg taaaatcaat aaagaatttg taaaatcaat
    70381 aatacaaatg caaatatgga ttatataaac taatagaaaa atcacttgaa tggcataata
    70441 agttgtgcta taataatgta gttgataatg taaaaagaaa gttaatataa ttaatttttt
    70501 taaataaaga gaagaggtga ctataatgca aaaggaaata caaccaaaat acaatccagt
    70561 tgaagtgcgt tgtgcttgtg ggaacacatt tgttgctggt tcaactaagg acgaaataaa
    70621 agttgaaata tgttcagagt gccatccatt ctatacagga aaacaaaaga acatagaaaa
    70681 aggtggaaga atcgacaaat tcaagaaaag attcaaaatg gactaatttt tataaaagtg
    70741 gagttggagg aagccaactc ctattttatt acaaaaaaac attcatattc tactttaaat
    70801 tgtctttttg tattataata ataaatatgt aaaattgagt attctaaata caataaaatg
    70861 aggtgagtgg atggcaaaac aagctgtagg tgggcaagct gttattgaag gtgtaatgat
    70921 gcagtcaaaa gacaaaagag cggtagctgt tagaaaaagt gacggagaaa tagcactaaa
    70981 agaagataga ataaaaagtt gggtaagaga taagaatata gataagatac cttttgttag
    71041 aggttctttt gttatgatag atacaatgat tcaaggcata aaaagtttaa acttttcttc
    71101 agagtttttt atggaagaag ctgaagagga taaatttgat ttatttataa agaaaatttt
    71161 taaagataag gcaaatgata taattataat attttcattg gtcatagcaa tgttactttc
    71221 tgctggatta ttcattttta tacctacatt ggtaggagga gctttttcta aagtaatgcc
    71281 taatgatttt atgcttaatt taatagaagg aatcataagg atagctatat tatttgcata
    71341 tatagtattg atttcacgaa gtaaggatat agaaagagtc tttcaatatc atggagcaga
    71401 acataaatct atatattgct atgaaaatga tttagaactt acagtagaga atgctagaaa
    71461 atttaaaaga ttacatccta gatgtggtac aaatttccta tttatagtta tggctgtatc
    71521 aataatattg tttgcatttt ttggttggcc aaatccaatt cttagaatat ttatgagaat
    71581 tatatgtgtg cctatagtag caggtttatc ttatgaggta attagagttc ttgggaaata
    71641 tgataatgga tttactaaaa ttattgcata tccaggaatg atgttgcaat attttacaac
    71701 aaaagagcct gatgatgagc aattagaggt tgctttggaa gcattgaaag cagtagtaga
    71761 ttagagaaaa ggatatttgt tatgacgata aaagatataa ttattaaata ttcagataaa
    71821 ctaaaagata taagtgatac tccaagatta gatacagagt tattgttaca aaaaacattg
    71881 ggtgttgata gattatatat tcacttaaat ctgaataaag agctaactga agaacaaaaa
    71941 acaaaattta tgggttttgc agaagaaaga ttaaatggaa gaccaatagc atatatagtt
    72001 gaaaataggg agtttatggg attagatttt tttgttaagg aaggcgtatt gattccaaga
    72061 ccagatacag aaactttagt agaagaaata attgaaatat gtagagaaaa aaaagatgta
    72121 agtatattag atataggaac tggttctgga gctattacaa taagtttagc aaagtacatt
    72181 gaaaattcta aaatcatgtc ttttgatata tcagagacag cattagaaat agctaaaaaa
    72241 aatgctatta taaatgaagt tggtgaaaaa ataaagtata ttaattctga tttatttaca
    72301 gcaataagtg atagtaacat aaaattcgat atcatagttt caaatccacc atatattaaa
    72361 aaacaagata tagaaactct gcacaaacaa gttaaagatt atgaaccata taatgctctt
    72421 gaaggtggag aagatggatt agacttttat agaagaataa cagaacaagg taagaaatat
    72481 ttaaataagt gtggaatatt agcatatgaa gttggtcata atcaagctga agatgtaata
    72541 aatattatga aaagtaatgg atataaaaaa atatacacaa agaaggatat tcaaggcatt
    72601 gatagagttg ttataggtta caatatatga tataatcaac aattgatatg ttacatttaa
    72661 tcgaggtgaa agtatgttaa aaaaattaga ggtattggaa gatacatata aagacttaag
    72721 tgaaaaaata ggtgatccgg atgtaataaa tgatcaaaaa gtttggcaga aatatataaa
    72781 agaacatgct gacttggaac ctattgttat gaaatacaga gagtataaaa gcgttttaga
    72841 tagtataaaa gaatcaaaag aaattttaca agaagagtca gatgaagaat taagagaatt
    72901 agctaaaatg gagttagctg agatggaaga aaaagtagca cctctggagg aagaaataaa
    72961 aatactatta ttgcctaaag accctaatga tgataagaac gttatagttg aaattagagg
    73021 tggagctgga ggagatgaag cagctctatt tgctggtgat ttatttagaa tgtactcaag
    73081 gtatgctgaa agaagaagat ggaaaataga attattgagt gcaagtgata ctggagttgg
    73141 tggatataaa gaagtatctt ttatgataaa aggtaaaggt gcttattcaa gattaaagta
    73201 tgaatctgga gttcatagag ttcaaagaat accatcaact gaatctggtg gaagaataca
    73261 cacatcaact tctactgttg cagtattacc agaagttgaa gatgtagagg ttgaaataaa
    73321 tccaaatgat ttaagaatag atgttttccg ttcttcaggt aatggaggac aaagtgtcaa
    73381 tactactgac tctgctgtta gggtaacaca tatacctaca ggtgaagtag tatcttgtca
    73441 agatggaaaa tcacaattaa aaaataaaga gcaagcttta aaaatattaa aagctagact
    73501 ttacgataaa gcattggcag aacaacacaa agatatagca gcagaaagaa aaagccaagt
    73561 cggaacagga gacaggtcag aaagaataag aacatataat ttccctcaag gtagaataag
    73621 tgaccataga ataaatttaa ctttatataa gttagatgca ttcttagatg gagatataga
    73681 tgaaatgata gatgctttaa ttactgttga ccaaacagaa aaaatgactg caatataagt
    73741 aatgttttaa agaagctgtt tcttcctaga aattattttc tattttgaaa cagctatttt
    73801 gcattttagg tcatgttatc atattctatt gtatataatt gttatataca agtataggag
    73861 ggttatatga tactaaaagt aacaataatt gggcttttgg caggtgttat agggacagga
    73921 ttaggaggag taatatcagc catttttaaa agagaggtcg ataaatatct aagttttttt
    73981 atgggattat ctggtggaat aatgttggct gtagtggtgt ttgatttaat gaaagaatcc
    74041 atggacaaaa tggggataat caatacagtt atatttacgt ttgttggagc tctcataact
    74101 atgtacataa aaacaaaatt agatgtgtct ggaaatatgg catctggata tcttatattc
    74161 ataagtatat tactacataa tttaccagaa ggactagcca ttggttcttc ttttatgtca
    74221 actgaaagtt taggtattac acttgctata gttataggtc tacataatat accagaaggg
    74281 ttagctatgg cattaggctt agtttgcaat aaaatgaaac taagtaaagt tattttgttt
    74341 actgtaatag ctggattacc tatgggtcta ggaagttttt taggtgttta ttttggagga
    74401 gtatttactt ctcttatagg agtatttctt gctacagcag gaggtactat gatgtatgtt
    74461 gtattggaag aaatttttcc acattcaaaa agtgtgtatt gtataattgg tttcttgtta
    74521 ggtacaatga ttgtaaatta tatataaaat taaaatgaaa gcaggcatac aaaagatgaa
    74581 aactattata agtaatattg atataaataa tattgattat gaggaaataa aaatacaagc
    74641 aaaacttctt agagaaggta aaacggttat ttttccaact gagacagtat atgggttggg
    74701 tgcaaatgca ttagatgaaa atgcagtaaa gaagatttat gaagctaaag gaagacctag
    74761 tgataatcca ttgatagtcc atatatatga aaaagaagaa gtatatgact tagccaaaga
    74821 tataagtgat aaagctaaac ttgttataga aaagctttgg ccaggaccta taacaattat
    74881 attaaataaa aaagatataa ttccatacaa aactagtgga gggcttgata cagttgcaat
    74941 aaggatgcct tctaatgtta ttgccagggc aataataaaa gaagctggta tacctattgc
    75001 agctccttct gcaaatatct caggtcgccc atctccaaca aaagcaaaac atgtatatga
    75061 agagatgaat ggaagagtgg atggaatagt tttaggagga gacagtaatt ttggattgga
    75121 gtcaactgta ttggatttaa cagaagagac tcctatgata ctgagaccag gaagtataac
    75181 taaagaagtt ttagaggaac ttcttggaga agtaaagctt gacccatcat taagtaaaaa
    75241 agaagataat caaaaagcta aagctcctgg aatgaaatat aaacattatt ctccaaatgc
    75301 agatgtatat ataatatctg gaaaaagaga aaatgtagca acaaagatta atgatatgat
    75361 aaaatctaat agagacaaag gtctaaagac aggtgtaatg tgtattagta gaaaccgaga
    75421 gttttatgat ggagaagtaa tcgatttagg aaactctctt gaagaagttg caagtaatct
    75481 gtttgatgct cttatagaaa tggacaaaaa gggtgttgat gtcatatatt cagaagagtt
    75541 ccccaagact ggagttggac aagcaattat gaatagacta ctgaagtcag caggatacaa
    75601 agtgataaag gcttaagagg gagttgtaaa atatgaatat acttattgtg tgtacaggta
    75661 atacttgtag aagccctatg gctgaggcta tactaaggaa agcaattaaa gaatctggaa
    75721 gaagtattga agaatattct atatcatcag caggtatatc tacagcaaat ggaatgggtg
    75781 cttctgaaaa ttctatagaa gtactaaaag aaatcggtat agacttatca aatcatagaa
    75841 gtaaagtaat tactaaaaaa ttaattgatg aatcagatat aatactaaca atgactaaat
    75901 ctcataaaga aattttagta caagcagttc caaaatgcaa agaaaaagtg tatactttta
    75961 aagggtttgc aaataaaaat gaggaagata tatctgaccc atttggtgga aatttggata
    76021 tttatagaag cactatgaga gaaataatgt attctgtcaa cgaaatagta aaaaaaatat
    76081 gaaacggagg ataaacaaat gaagatagga ttaggctgtg accatggagg atataattta
    76141 aaaaaagaaa taataagcta tttagaaagt aaaggtatag agtgtgtaga ttatggaact
    76201 aataatgcta cagattctgt tgattatcct gtttatggag aaatagttgc aaattcagtt
    76261 ataaataaag aagtagatta tggaatatta tgttgtggta cagggatagg aatatcttta
    76321 gctgctaata aggttcctgg gataagatgt gcagttgtat cagatgtatt ttctgcaaaa
    76381 atgtcaaaag cacataatga tgcaaatatg ttatcattag gcgaaagagt tttaggaaaa
    76441 ggtctagcac ttgagatagt tgaagcatgg attaatacgg attttgaagg tgatagacat
    76501 gctagaagag taaacatgat taaatcaata gaagaaaaac ataataaata ataaaaatta
    76561 cagttttatc aggaggaatt atcaaaatga gcaaagtggt agagacaaac catccattaa
    76621 tacaacataa attaacttta atgagagata aaaatactgg ttctaaagac tttagagagc
    76681 ttttaactga aattgcaatg ttaatggggt atgaaataac aaaagatata ccattaaaag
    76741 atgtagaaat agaaactcct attcaaaaaa catcatctaa agtagttgca ggtaaaaaat
    76801 tagcaataat tccaatttta agagcaggtc ttggaatggt agatggatta gtgagcttaa
    76861 tgccagcagc aaaagttgga catgtaggac tatatagaga cccagaaaca ttaaaaccag
    76921 ttgaatatta ttgtaagctt cctcaagaca taggagaaag agatataata gtagttgacc
    76981 ctatgcttgc aacagggggt tctgctgtag cagctataga tttacttaag tctaaaggag
    77041 ctaaaagtat aaaattagct aatttagtag ctgcaccaga aggtatagca gaagtgcaaa
    77101 aatatcatga tgatgttgat atatatgttg catcagttga cgaaagatta aatgaacatg
    77161 gatatataat tcctggtctt ggtgatgctg gagatagatt gtttggaact aaataaaaat
    77221 aaataactat aaatatttat tagggacttt cttatatagt gtatataatt ttatgtaaga
    77281 aggttctttt ttatatattt tttctcaaaa taggaattat tgaattgata aatttctcga
    77341 attgagaata aaaagttttt accaattaaa aaagattgct tattttacaa ggttttatag
    77401 aatagtagtc tattttaatg tggcatgtta gttgcttacg attataggta ttaagtgtat
    77461 tagttaaatt gagaattgaa tattaataat attattggga gtggtaatac atgaagaatt
    77521 gtatagtagt aagaggggct ggagatttag caacagcagt tattcataaa ttacacaaca
    77581 gtggttttaa agtagttgcg ttagaaatag aagagccatt agctataaga aggcaaattt
    77641 ctttttgtga ggctgtttat gaaaaaaaag taactgttga aggtgtagaa tgtatatttt
    77701 gcaatactga aaaagaaata gaggaagttt tatctcaaca taaagtagcc ttgattatag
    77761 acccaaaagg agaaaaatta tctaaattaa atccaatcgt tttggttgat ggaatactcg
    77821 ctaagaaaaa cttaggtaca actaaagata tggcaccact tacaatagct ttaggtcctg
    77881 gattttgtgc aggagaagat gtagatgttg ttatagagac aatgagaggt cataatctag
    77941 gaagaataat aactaatggt agagcagaaa aaaatacagg agtaccagga gcaataaaag
    78001 gtttttctaa agagagagtt atgcattcac agtatgatgg cataatggaa aatgtatgta
    78061 agataggtga tatagttgaa aagggagacc tactttgcta tattaataat tatgaaaaaa
    78121 aacatgaagt tagagcaaca atatctggag tccttagagg tttattaaag gatggagcaa
    78181 aggtaaacaa aaatttaaaa atactagaca tagaccctag aaaagaagaa gttaagaatg
    78241 cttttacaat atcagataaa gctagatgta tagctggagg ggttttagaa gccatactaa
    78301 acaatgggat ttatccccaa aattaattta tattagataa agctattaat attttattaa
    78361 gatgatataa taaatttaat agattaaaga gagcatatga cgggtattta aaatttaaat
    78421 ggtaaaaatg ctcttttttt attggacatt caattaacat gtgtatataa tataaaaata
    78481 agtatttatt taggttgaaa tctaataaat atataatacc agtacataag caaagaggag
    78541 aaaagtaaat tatgagacca tcatgggatg aatacttcat ggaaattgca gaagtagtga
    78601 aaaagcgttc aacttgtatt agaagacaag taggagctgt aattgtaaga gacaaacaaa
    78661 tattaacaac tggatataat ggttctccga gaaatcttga acactgtgaa aatattggat
    78721 gtaagaggca ggaattaaat attccctcag gagaaaggca tgaattatgt agagcattac
    78781 atgctgaaca aaatgcgata atacaagctg ctcataatgg tattagtgta gatggggcaa
    78841 ctttgtatgt tactacaaga ccttgtgttt tgtgtgcaaa aatgtgcata aatgcaggta
    78901 tattgaaaat tgtttatgaa ggtgattatc cagatgatat gtctacagaa ttattaaaag
    78961 aagcaggaat agaactcata aaattttagt ggataaaatt tatatgacaa taaatgtcaa
    79021 attatgacac tgaaatacaa tggtatcaaa tgattaaaag aaagtatttg aaaaatcatc
    79081 agattagtag taagatatat tttataatta aataaattta tgagatagat taattacatg
    79141 ttatttattt tataataatg agggatacta tttatgagta aaagaaatac acatacagaa
    79201 attgcaaagt tgtttagttt aataagtcaa ataggattga tgattgtaat atcaatatta
    79261 ggatgtactt tcttaggaaa atttttagat agtaaattga atactactcc agttctgaca
    79321 ataatatttt tattgttggg tgttggaggt gcttttagtg gtgtttataa aactctaata
    79381 gtatatacac gaaggaagtg atatattgga tataaaatta cttaaccagg taaggtcagt
    79441 aacaaaaggt atagtaatat ttgatgtagt tttaattgtg ctaatgttga taacatcaac
    79501 attaagtaaa ccagtattat taggacttat atttggctct ataatagcta tgttaaattt
    79561 tagattattg gcgatatcac tggaaaaatc agtgacattt cctgctggga aggcacaagc
    79621 ttatgcatca gcacaatatg ctgttagatt atttataatg gcagttgttc taattgcatc
    79681 agctacagta ccacatttaa atataatcgg aacagcattg ggattattga gcacaaagtt
    79741 tgtcatatta tcaaaaaact ttataaataa attaaagagg aaggaggcat aagtatgaat
    79801 caagcgcatt attatctcat aggaaacttt aagattagtg aaacaatact agtaagttgg
    79861 ggaataatgg cctttttagc gatagcatct tattttttga ctagaaactt aaaaaaagtt
    79921 ccaactagta aagttcaaat attcttagaa tttgcagtag gtggtcttgc taaaatggtt
    79981 acagatgtta tgggtaaaaa tacagtaaaa agaatgccat atatgatacc atacatagga
    80041 agcttgtttt tatttttcgc atgttcaaat ttaagcccat tacttggatt aaggtcacca
    80101 acaaccgact tagacacaac tgctgcatgg gcaatgatta cattttttat gatttatttt
    80161 gcaggagtta aatttaaggg gttatcatac tttaaagaat tggctcaacc acttgccata
    80221 atgttaccaa tcaatattat aggtgagtta gctagaccaa tatcattaag tttccgtcca
    80281 tttgggaata ttttaggtgg aacaataata atgggtctgt tttatcaact tttaggtttt
    80341 atatctagtt taataccagg attatcaata ccaattggag aaatattaat accagtccca
    80401 ttacacttgt actttgactt atttgcagga ttgttacaag catatatatt tataatgtta
    80461 acaatggtat ttatatcaag tgcaggagag ttagattaag aaatcaactt atattaagat
    80521 aaaaataaaa taatttaaaa aattaaagtt ttaaggagga aataattatg gaaacagcaa
    80581 tagtagcggc agcatcagca ataggagcag ggatagcagt tgcaacaggt ataggtgcag
    80641 gtataggtca aggtatagca gcagctaaag ctgcagaagc agtaggaaac caaccagaag
    80701 ctaaaggtga tataacatca actttattac taggagttgc tatagcagag tcttcagcaa
    80761 tatatggttt ggttatatca ataatacttc tattcgtaaa tccattcttt aaatacttag
    80821 gaatgtagat ttagtcctta aatattttga gataggttta taggtaaatc atctcaaact
    80881 tataatcatg agatgaactt tatcatctcg tgattataag tagttatgat ttatggaaag
    80941 gaggataatt atggaaaaag cactagtagg tataacgtgg gaatttgtgt tccaaattgt
    81001 taatactttt ataatatttt tacttctgag aaagctttta ttcaagccag tattaaatat
    81061 aattgaatca agagaaaatg atattaaaag tgatttggca gaaggcgaaa aagcaaaaaa
    81121 tgaaggttta gctctgaaaa aagaatatga gtcaaaaatc aattttgcca aggatgaagg
    81181 tcaagaaatc ataaaacaag caactataag agcagagcag aaatcagatg atatagtaaa
    81241 tactgcaaag aaagatgctc ttgatataaa agaaaaagca aacaaagata tagaacaaga
    81301 aagacaaaag gttataaatg aaatcaaaaa tgatatatct aacatagcac tacttgcagc
    81361 atctaaagtc attgaaaaag atttagataa atctaaacat gaagaattga tagaaaactt
    81421 tataaaagag gtaggggaag ctaaatgata aatgtaatag caaatagata tgcagaagcc
    81481 ctatttcaat taggagaaga agaaaattca actgatgtct tattcaaaga actagaaaaa
    81541 gtagtagata tgatgactaa agttagtaaa gatttctaca aagttttaaa atcaccatta
    81601 gtttcaaaat cagaaaagaa aaacttggta gaaattattt ttagtaaaga agtaagttct
    81661 aacataaaaa actttttaaa agttttagta gataaagata gaatatcata tttagaagat
    81721 atcgaattag cttataaaga attattaaat aagaaaaaca atgtaattga tggagtagca
    81781 ataagtgcta ttccaatgag tgaaacagat attaaagaac ttgaagtcaa actttcaaat
    81841 aaatacaaca aaaatgttac tatagaaaat gttgttgaca agactatact agggggagtt
    81901 ctagttagaa ttggaaatga acaaatagat ggcactgtga aaactcgtct tgataagatg
    81961 aaagaaaagc tatctgaagt aatatcttaa gaatggcggt gaacccatga acttaaaacc
    82021 tgaagaaata agttctataa ttaaacagca aataaaaaat tatgagaata aagttgagtt
    82081 gacagataca ggtagtgttt taacagttgg ggatggtata gcgagtgtat atggattaga
    82141 aaaagctatg tctggtgagt tgctagagtt cccaggtgaa atatatggta tggcacttaa
    82201 cttggaagaa gaagtagttg gagctgttat ccttggagat gacagtgaaa taaaagaagg
    82261 cgatatagtt aagagaactg gaagaatagt tgaagttcca gttggagaag ctttaatagg
    82321 tagagttgta aactcactag gtcagccaat agatggaaaa ggacctatag cgtacacaaa
    82381 aactagacca gttgaatctg aggcacctgg tataatagat agaaggtctg tttatgaacc
    82441 attacaaaca ggaatcaaat caatagattc aatgatacca attggtagag gtcaaagaga
    82501 gttaataata ggtgacagac aaactggtaa aacatctata gttattgaca ctatactaaa
    82561 tcaaaaagga aaagatgtta tctgtatata tgtagcaatt ggacaaaaac gttctactat
    82621 agctcaatta gttagctctt tagaaaaagg tggagctttg gattatacaa tagtagtttc
    82681 agcaacagca tctgaatcag caccacttca atatatagca ccatatgctg gagcagctat
    82741 gggtgaagaa tttatgtaca atgggaaaca tgtacttata gtgtatgatg atttaagtaa
    82801 acaagctgtt gcatatagag aaatgtcatt gttacttaga agaccaccag gacgtgaggc
    82861 atatcctgga gatgtattct atttacattc aagattactt gaaagagcag ctaagttatc
    82921 tgatgaattg ggtggaggtt caatgactgc cttgcctata atagaaactc aagctggtga
    82981 cgtttctgca tatataccaa caaatgttat atctataaca gatggtcaaa tatacttaca
    83041 accagagtta ttctattcag gtgtaagacc agcagttgac cctggtatat cagtatcaag
    83101 ggttggtggt tctgcgcaaa ttaaagcaat gaaaaaagtt gcaggaacat taaaacttgc
    83161 atattcacaa tatagagaac ttgcagcatt ctcacagttt ggttctgact tagatgaaga
    83221 tactaaaaag agacttgctc aaggtgaaag aatcgttgag atattaaaac aaggtgagca
    83281 tcaaccaata aaagttgaaa atcaagttat gataatatat gctgttataa ataatcattt
    83341 agaggatatt ccgatagata atatagctag atttgaatca gaattgtatg catttgtaga
    83401 taataattat ccggaaatat caagaaaaat attaggtgga gaagacttca ctcatgattt
    83461 aacagatgca ataaatgaat ttaaagaaaa gtttgttgtt gaagtataat cctttttaaa
    83521 aaaggaggta aattaattgg caggagctgg aatcaaagca atcaaaacac gtatgggaac
    83581 tgttgaaagt acaaagcaaa taactaaagc aatggaatta gttgcatctt ctaagcttag
    83641 aaaagcaaaa gaaaaggctg aagattcaag agaatatttt aatactttat acaatacagt
    83701 aaaagatatt gcccaaacaa cacgtggaat tagaaatgaa tttttaaaag aaagagaagt
    83761 aaaaaataaa tgctatgtag tagtagctgg agacagagga cttgcaggtg gatacaattc
    83821 taatgtatta aaggaatctg tctctcatat gaaaggtaaa aaggaaacag tgattactgt
    83881 tggaaagaaa gcacatgaat ttttttctaa aagaaactac aatatagcaa aagatataaa
    83941 tagtgttgaa gcttgtggat atgaagatgc gacagaaatt tcacaaacta ttattgacct
    84001 gtataaaaaa ggtgaagtag atgaagttta tattgcttat acaaaattta aatctgcttt
    84061 atcacaagaa gttgaaattt tgaaattgct tccattagtc tttgaaaaag atacagacga
    84121 acaaggaatg gcagtaaaag aagaaaaaca aaatagatca aaagtacaat atataccatc
    84181 agcagaagca gttttaagtt atattgtacc tcagtttata tcaggtacag tatatggtgg
    84241 aattttggaa tcttttgcat cagagcaagg tgctagaaga actgcaatgg aatcagccac
    84301 agacaatgcg aatgaaatgc tatctaattt agagttaagt tataacagag caagacagtc
    84361 agctgtaact caagaaataa cagagatagt tggtggagtt gaagctctaa aatagggagg
    84421 ttaggaaatg gcaaatgtag gtaaagtagt acagattgta ggagctgtac tagatgttaa
    84481 gtttgatagt gaacaaagcc tacctaactt attaaatgcg ttagtaataa agttaggaga
    84541 taaagaaata gttgcagaag ttgctcaaca tataggtgat gatactgtaa gatgtatagc
    84601 tatgagtgca acagacggac ttgtaagagg tatggaagtt gtagatacag gagggccaat
    84661 aagtgttcct gttggagatg aaactttagg tagaatattc aatgttcttg gaaaaccagt
    84721 tgatgggaaa ccagctccaa aatctgcacc taaattacct atacatagac cagcaccagc
    84781 atatgatgaa ctagaaacta cagcagagat actagaaact ggtattaagg tagttgactt
    84841 actagctcca tatctaaaag gtggaaaaat aggtctattt ggaggagcag gagtaggaaa
    84901 gacagttcta atacaagagc ttataaacaa tattgctaag caacatggtg gtatttctgt
    84961 gttttcagga gtaggagaaa gaacaagaga aggtaacgac ctttatggcg aaatgagtga
    85021 gtctggagtt ataaataaaa cagctctagt atttggtcaa atgaatgaac cacctggagc
    85081 gagaatgaga gttgctttaa ctggacttac aatggcagaa cattttagag atgagcaagg
    85141 acaagacgtt ttacttttcg ttgataatat attccgtttc acacaagctg gttcagaagt
    85201 ttcagcactt ctaggacgta tgccatcagc tgttggttat cagccaacat tagctactga
    85261 aatgggtgca cttcaagaga gaataacatc aactaagaaa ggttcaataa catctgttca
    85321 agcagtatat gtaccagcag atgacttaac tgacccagca ccagctacaa cattctctca
    85381 cttagatgca aaaacagttt tatcaagaca aatatcatca ctgggtatat atccagcagt
    85441 tgaccctctt gaatctacat caaggattct tgaccctagt atagtaggaa aagaacatta
    85501 tgaagtagct agaggtgtac aatcaatact tcaaagatat aaagaacttc aagatataat
    85561 tgctatactt ggtatggatg aattatctga tgaagataag ttaatagttg cacgtgctag
    85621 aaagatacaa agattcttat ctcaatcatt cacagttgct gagcaattta caggaaatcc
    85681 aggtcaatat gttcctgtta aagagactgt aagaggattt aaagaaattc ttgaagggaa
    85741 acatgatgac ttaccagagt cagcattctt atttgtagga acaatagaag acgctgttag
    85801 aaaagcgaag ggaagtatgt agtcatggcc agtgaatttt cattgaaagt tgtaactcca
    85861 agtaatactt tttatgatgg agatgttgaa atgatagtag ttagaactac aaaaggagac
    85921 aaaggggtgt tgaaaggtca tataccattt gtttcaggta tacctgtagg aactttaaag
    85981 ataaaaaaag agggaagttt taaagaggcg aaaatagcag aaggattcat taatgtaact
    86041 caagataaaa ctgtcatatt gacagaatct gctgagtgga tttaataaat taatttagag
    86101 tataaaaagt cattttgacc aaaaaaactt ttgggtaaaa tggctttttt gcgttttggt
    86161 gttaataaaa taacgataaa attgtaagtt tttagtgata ataaattcac aaaatgttta
    86221 aatttactgc caaattatgt tgtaattaat aagataaaga agatttagat agcttttatg
    86281 taagtgaaaa agtcttcata taagaaatac atataaaatt tttataaaat ttaaaaaatt
    86341 tgcttagttg tgtagtataa taaataatat aatagatttg tatataatat tcattacaaa
    86401 taattttaaa agttacagtt ttattataat gattattaaa ttaagataag taacataaac
    86461 taaataataa tgtgtattat cgatagtaaa tttataaatt cattattaat tattgaaaga
    86521 agtattataa attttctgga ggaacaatga atatatttga tattggcgta gatataattg
    86581 aaattgatag aataagaaag gctgtagaca aaaataatag gtttttggag aagatattta
    86641 cagatagaga aatagagtat tttaattcta agaattttaa agcagaaagt atagcaggta
    86701 atttcgcagc caaggaagct ataagtaaat ctataggtac aggaattaga ttgtttaatt
    86761 ttaaagatat agaagttctc agaaatgaaa tgggaaaacc aatagtaaaa acttataata
    86821 atctagcaaa aatgtgcata gattataatg ttttagaaat aaaagtttca atatcacatt
    86881 caaaagatta tgctatagca aatgcgataa ccataattaa ggactaagga gtgattacat
    86941 tatgatggat aaaacagcaa aagaaataat gacaacagat gtaatagtag caaaacaaga
    87001 tgatagtata gcagatgtag ctaatatgct aattgcagaa aaaataggag gtctgccagt
    87061 tgtagattca gagaatagag ttgttggaat aatttctgaa acagatattc ttaaaaaaga
    87121 aaaatatata gaagcacctc tctatataaa tctattacaa ggattgattt tcttagatga
    87181 cttaaaaaaa gttgaaaaag atataaaaca agtagctgct tataaggttg gagaacttat
    87241 gtctaaagat ataataaagg ttcatgaaga tgataagttt gatgatgtag ctaatgtaat
    87301 gattaaaaaa tcaataaaca gagttcctgt agtagatgat gacaacaaac ttaaaggtat
    87361 aatttgtaga tatgatataa taaaagcttt atacaatgaa taaactgaag taggaggtgt
    87421 gatgtgagaa aaaagtggac catagtatgt attatgttct tggcactggt tataattgta
    87481 ataggatgcc aaaaacgaca gtccacaaaa gaagaagtat acaaagattt tcaaaagcag
    87541 atttctgata tgaattatta cagttgtaaa gctgaagtag aagtagttgg aaataaaagc
    87601 ccacacaatt atgttttaat tcatacttat aaaaaaaccg ataactataa attagaagta
    87661 atttccccaa aacatttaaa agggaaaagt atagaatatc aagatgataa aatattagtt
    87721 aaaaatccaa agattagtga tgtagtggag ttacctaata caggaaaaaa taatcaatat
    87781 ctttttgtag gagactttat aaaaaactat cttcaaaatg aggagatgaa agtaaagtta
    87841 tccaaaggac atttggtttt agagactttt attcctgggg ataataaata ttttaacaag
    87901 caagtattat atgtaaatgc tgacacaaaa aatcctgaaa aaatggaagt gttagataaa
    87961 gagggagtgc caagatttac agtaaaatac aaagattttg aatacagaaa ctaaggggga
    88021 ctaaagacat gcaaaaaata acagtgccta catgggcaga gataaatcta gataacttaa
    88081 gatttaactt aaataatatt aaaaatttat tagaagaaga tattaagatt tgtggagtaa
    88141 taaaagctga tgcatatgga catggtgcag tagaagttgc aaaattgcta gaaaaagaaa
    88201 aagtagatta cttagcagta gcaagaactg ctgaaggaat tgaacttaga caaaatggca
    88261 taacacttcc tattttgaac ttgggatata ctccagacga agcttttgaa gattctataa
    88321 aaaataaaat aactatgaca gtttattctt tagaaacagc acaaaagata aatgaaattg
    88381 caaaatcttt aggagaaaaa gcctgtgttc atgttaaaat agactcaggg atgactagaa
    88441 taggtttcca acctaatgag aagtcagtac aggaaataat agaattaaat aaattagaat
    88501 atatagattt agaaggtatg tttactcatt ttgctacagc tgatgaagta agtaaagagt
    88561 acacttataa acaagctaat aattataaat ttatgtctga taaattagat gaggctggtg
    88621 taaaaatagc tataaaacat gtatcaaaca gtgcagctat tatggattgc cctgatttaa
    88681 gattaaatat ggtaagagca ggaataatat tatatggtca ttatccatct gatgatgtat
    88741 ttaaagatag attagaatta agaccagcca tgaaattaaa atcaaaaatc ggacatataa
    88801 aacaagttga accaggtgta ggaataagtt atggactaaa atacacaact acaggtaaag
    88861 aaacaatagc tacagttcca ataggatacg cagatggatt tactagaatc caaaaaaatc
    88921 caaaggttct tattaaggga gaagtgtttg atgtagttgg tagaatatgt atggatcaaa
    88981 taatggttag aattgacaaa gatatagaca taaaagttgg agatgaggtt atactatttg
    89041 gagaaggcga agttacagct gagcgtatag ctaaagactt aggaactata aactatgaag
    89101 tgttatgtat gatatcaaga agagttgacc gtgtttatat ggaaaataat gagcttgtac
    89161 aaataaacag ttatttgcta aaataaaacc atgatattat aatctgggag gcgattttgt
    89221 gtacgataag agtaaagaaa aaatagaagt tactttacct gactctctga tttctgaagt
    89281 tgatagtata gttcagatgg agaacagtaa cagagaagat tttgcaaaag ctgcttttca
    89341 gttctatata actcagaaaa agaaaattca tattaaagaa tctatgaaaa cgggttatag
    89401 agaaatgggt caaattaatc tgtcactagc tgaattaggt atgacagttg aagaagtatc
    89461 ttctgatgat aaaaatgaag ggaagattgc ccaaggtgag tactaattgt gaaataaagc
    89521 gtggtgattt atattacgct gatttaagtc cagttgttgg ttcagagcag ggaggcgtta
    89581 gacctgttct gataatacaa aatgatgtag gtaataaata tagtcctaca gttatagtat
    89641 cagctataac atctcagatt aataaagcca aattacctac tcatgtagag ataagttcca
    89701 atgaatatgg gcttaataaa gactcagtaa ttcttttaga gcaaattaga actatcgata
    89761 aaaagagact gagggaaaaa attggttgtc tagatgaaaa tatgatgata aaagtagatg
    89821 atggacttca aataagttta ggattgttta ctttttaaag agggatttgt cttttattag
    89881 acaatccctt ttttctttta aatatctctt aaggtttaat tttaatgtac tatgttaata
    89941 aaattaaaaa taacgcaaaa aaatagcata aaagtgatat aataatatgg aattgatata
    90001 aaattacgaa ctcaagggag gtaattgcat gagagaccat aaaggattaa atgagattgc
    90061 gcgtatcata agaagagata tagtttcaat gatacataga gccaaatctg gacatccagg
    90121 agggtcatta tcagtagttg aaatacttac tgcgttatac tttgatgaaa tgaatgtgga
    90181 ttcttcaaat cctaaaatgg aggatagaga tagatttgta ttatcaaaag gacatgctgc
    90241 accagcatta tatgctacat tggctgaaaa aggctatttt gataaggaag aactgaatgg
    90301 attaaggaag ataggaagga tgttacaagg tcatccagac atgaaaggca cgccaggtgt
    90361 ggaaatatct actggttctt taggtcaagg tttttcagtt gcatgtggta tggctatggc
    90421 atcaaagttg gataatgctc cgtggaatgt gtatactttg cttggtgatg gtgaggttca
    90481 agaaggaatt gtttgggaag ctgctatgag tgctgcacat tataaacttg ataatttaat
    90541 tgctttttta gataataatg gacttcaaat agatggagat atagaaagcg taatgagttt
    90601 aggttcaata gttgataaat ttaaagcttt tggttggaat gtaattgaga tagatggaca
    90661 tgattttgac caaatatttg cggctcttga tatagctaaa tcaacagtta aaaaacctac
    90721 aatgatagtt gcaaaaacta taaaaggcaa aggaatatct tttatggaaa atcaagcagg
    90781 atggcatggg acagctccaa gtgatgagga gctagaaaaa gctttgcttg aattaggagg
    90841 tgctgacaat gagtaaaatg gcgacgagag aagcatatgg taaagcatta gtaaaattag
    90901 gtcaaataaa tgacaatgtt gtagtattag atgcagattt atcaaagtct acaaaaacac
    90961 atgattttta caagtcattt ccagatagat tttttaatat gggtatagct gaacaaaatt
    91021 taataggcgc tgcttgtgga ttatcaactg ctggtaaaat accttttgca agtacttttg
    91081 ctatgtttgc tacgggaagg gcttttgaga ttataagaaa ttcagtttgt tatccaaagc
    91141 taaatgtaaa aatatgtgct actcatgcag gtcttactgt tggagaggat ggagcatctc
    91201 atgaaagtgt ggaagatatt gctataatga gagctatacc aaatatgaca gttcttgttc
    91261 cagctgatgg agttgaaaca gaaaaaatta tttttgaaat agctaagtat aatggacctg
    91321 tttatgttag attagggaga agttcagtac cagttttatt tgatgaagat tataaatttg
    91381 aaataggaaa aggtacagtc ttaagagaag gaaaggatgt atcaattata gcttgtggaa
    91441 ttatggtaaa tgaagctcta ttagcacaag aaaagttgca agaagaaggt ataagtgcta
    91501 gagttataaa catgtcctcg ataaaaccta tagacaaaga tttaatatta gaatcagcaa
    91561 aagaaacgaa tgctattgta actgtagaag aacatagcat aattggggga ttaggttctg
    91621 ctgtaagtga ggtagtagga gagtcttgtc caaccattgt aaagaaagtt ggaattaaag
    91681 atacatttgg agaatctggt actccaaatg aattgttaaa aaaatatgaa ttaacttgtg
    91741 atgacataat aaagactgtt aaagaagtta ttattgcaaa aagaatgtaa gagatataaa
    91801 ttattcatgt ttgttaataa tataatatat ttaaaagaga ggtataaagt gttatattaa
    91861 tttatatctc tctttttttt atatgatatc aatatatcaa aaatgtaata aaatattcaa
    91921 atttttacaa aaatagagaa aatattcaaa tatatattga ctattcagaa aaatatgact
    91981 aatatataat ttatagagaa actaatttta tatataatga ctacttagat aaaagaatct
    92041 aaaaaaatta tgagaggagg agtagggtat aaaatcagat tataagtttt aagttattat
    92101 actaaaaagc tataaaacag ttatcatgta ttttatgtta aaggaaattg taggtagttt
    92161 atcgaattgt ttaatcagaa gaaaaaattt cacatgggga ggtaactgag atatgtcaga
    92221 aaaagtaaat gttaaaacag tcatcagttt cgcaggtgcg tatgtagcaa cagtaatcgg
    92281 ttctggattt gcaacaggac aggaaataat gcaattcttc tctttttatg gttttgcagg
    92341 tattattggt gggataattt caatggtatt attctcatgg atgggtgctt cagttatgtc
    92401 aaaaggtaaa gagcttcaac ttaaagaacc tatcaaaatt tatcgtgttt attgtggtaa
    92461 gtatttagga atattctttg aatggtttgg acctttattc ttatttggtg ttttcgtagt
    92521 aatgatttca ggagcaggag caactttaac tgaatactat ggattaaatc catttgtagg
    92581 tagagtaggt atggcagtag tagcattatt aactgtttca ctaggtcttg ataaattatc
    92641 aaagatacta ggtggaatag ggcctataat aataatcttt acacttttag ttggtggtat
    92701 aagtttagct aaaaacatag gtaatatagg agaagctgca caagttctta gcactgtaaa
    92761 gatagctaaa ccagttccaa atgcctatct atctggtgta atatatacta cttataacac
    92821 aattgttgtt atggcattct taactggatt aggagcaagt gctgctaaca aaaaagaagc
    92881 tatttgtggt ggtatattag gtggagtagc acttatggct gcagctataa tgatgcactt
    92941 agctattctt tctgatatag gaaacttata ttcaaaagca ataccatcat tattcttagc
    93001 agataagatt tcaccagtaa ttggagtttt attctcaata attcttatat taggtatata
    93061 tacaacagct gtacctttat tatggtcagt aactaataga tttgtagatg ataaacatcc
    93121 taagtttaaa ttaataactt taatagcagc tatattaggt cttataggtg gcttcctacc
    93181 atttgataag ctggttggta ttttatatcc atatactgga tatatgggcg tcataatact
    93241 ggtttgtgtt ctttatagac agattacaaa aacatctgga tatcaagaag gaatcagtga
    93301 caaataagta ttttttaata ttgtaaactc aagagctata tgaaaacaat gaaaatgttt
    93361 tcatatagct ctttttattt tttagctcgt ttattatgaa atagaaaaaa catgtttttt
    93421 agttacatta catatattta taattatgta taaatatata ctaatcaata atttagagtc
    93481 taagataagt ttataaatca tatatttaga atatatggga ggagtgataa gattgaatgt
    93541 aaagtttaat attaaaggta taatttatgg agttatagct cttgtattcg ttataggggg
    93601 atttatattc ataccaagta tgtttgtaga gaaatctaaa cccatagatt atacagtatt
    93661 acaaagaaat tcaataccag aaaagatatt agatgtgatg gataagtata caaatgaaga
    93721 aagagcatta gcggctaaaa tcgataacaa aatatacatt atagtgacta gaggaaataa
    93781 taaatatggt atagaaatgg acaaaataga aagtgtggtt gaggaaggaa aggatgtttt
    93841 gagagtcaag ataaagtata aagataagga agattctttt ccatacatag ttgttgaaac
    93901 aaatatgagt gaacttccag atagaataga attaaatgcg acgaaataag aaggtatttt
    93961 ataattaaat aactgcatat tgtacaataa agtcatggtt tttattaatg taagtaaatt
    94021 gtatatggtt cttattgttg taaaagccat gacttaaaat gcttataaag taagatatta
    94081 acagtagtat ttattactat attaaatggg gtctggaaat acttaatatt ctaattattt
    94141 ggagtgataa ttctagtttc agtaactatg tagtctaatt gtgcatcatg agtttctttt
    94201 ggaatagaat cgaatatctg gaagtcaaat gctatgccga tagttatagc atcttttctt
    94261 aagttttcta aaaatctatc ataaaatcct ccaccatatc ctaatctata gcaatgtata
    94321 tcatatgcta cagctggtac aattacaaca tctaaggcct taatatcaat tgtaggtgat
    94381 ttttcgttag gttctcttat tccatatgct ccaattctca atccctcttt taaatctgtt
    94441 atttgagtag ggattaatgt atgattttct tttattgtga tgggacttga tactattttc
    94501 tttagagaca aaagtttttt gattaaatta tctgtttgaa cttcattgtt aaaatttaga
    94561 taaagcatta tattagttgc atttcttata tcttccattt gaagtaattt ttcagtgatt
    94621 aaatttgaat tactaagtac gaagtttgca ctcttatttt ttcttgattc aataactttt
    94681 tttctaaatt cttttttcat aaaataattc ctcccttaat atgttataat gtgtacagca
    94741 attgtattta atataaattt tagtataatt tattgtaata aagcaatata tttgggtaaa
    94801 tgtaataaaa ataacagcta gtcatataat aataatagtt tatgtaaaag gagatgtatc
    94861 ttgtgatttc aaagaagaaa gctatttttt taggggtgat tttagtaatt ataacagcta
    94921 tggttacatc agcatttcag ttgacattgg ggaataaagt tgtaatatcg aaagaactct
    94981 atgaagacta taaaaaatat gataagttgt taggactaga atctattata aaacaagatt
    95041 tttataaaaa agtatcagat actgatttgg taaatggagc agcaaaaggt ctatttctag
    95101 gaacaaatga taagtattct ggttattata ctaaagatga aatggagaat ctaattaatg
    95161 atagtgaagg ttcttatgtt ggtgtaggta tgtatatagg ggcatcaaaa gatggtggct
    95221 tagtagtagt tcccatgaaa gattctccag cagagaaagc aggtgtaaaa tcaggggata
    95281 aattagtaaa agtcaatgga aaatctgtct catataaaaa ttcagatgaa gctgttcgta
    95341 tgatgaaggg taaaaaaggt aaaacagttg aactgactat attaagagaa gataaacaat
    95401 tgaactttaa agtaaaaaca gaccagataa ttgagaagag tatagaaagt aaagtaattg
    95461 ataatgattt aggatatata gaaattaccc aatttatatc aagtacatat actgactttg
    95521 ataaagcttt aaaagaatta aaagcaaaaa atatcaaggg attagtaata gaccttagaa
    95581 ataatcctgg tggaatgcta gatatatgta aagaagttgc tgatgagtta attggtgaag
    95641 gaactatagt atatacaaaa gataataagg gaaatactga gtacttgaaa tctgataaag
    95701 aaaaattggg acttccaata gtagtgttaa ctaatggaga aagtgcttct gctgctgaaa
    95761 tattaacagc tgcaatcgtt gataataaag aaggtatttc tgtagggact acaacttttg
    95821 gtaaagggtt ggtacaatca gttgtaagat tgaaggatgg aacaggatac aagttaacta
    95881 ctgctcaata ttttacacct aatggagatt atatcaatga aaaaggtata aagcctacta
    95941 ttgaagaaaa agatgaaaat aaacagttag atgtagcaac taagtggctt agagaacaga
    96001 ttgataaata ggatttaatt tttataaact tatactataa aataaagaac attataaaag
    96061 agatgtctca aaatgaactt tttagttcat gagggagtct ggaaatattt atgtgtattc
    96121 tttaaataaa aatttatttt ttaagtgata attaaatttt tacagacagg gctatggttt
    96181 taaaaatcat agccttattt tgatattttt taaaaacaca ttgcaaccca gttgttccaa
    96241 atattatatc atttactttt aaaatatcgt aaactgcata ctatatattc attataatat
    96301 aatttatcta actagaacct cagtttacta attaaattag atgcatagaa taactttttt
    96361 aaacattgaa aataaattaa actctaaaca catttaaata taaatttata tatcattttg
    96421 acttggttaa acaatttcat acttatcgat ataaaaatag gttataatat aaatgttcat
    96481 tatcttataa cctattttat ataatttatt cctaaaacat gtgaatgttt tttatgatag
    96541 tttgaagaaa ttataaaatc actttataat tgaatattat atataaatta atttaaatat
    96601 agaaaggaaa atatatgtac aacaatatca aaaatatttt aaaagaaaat catataacgt
    96661 ttgaagaata tgaccatgaa cctattttat catttgaaaa agctaaagaa ataagagaaa
    96721 aattacaata tactggagta gaaagtaaaa gtttatttat aaaagataga tctggaaatt
    96781 actatatatt tgtaaccaca gaaggaaaaa aattagatcc aaaaactata aaaaatgttt
    96841 taggtggaaa agtatctata tgttcaaaag aagaattaac acaaaaaaca caatgtttgc
    96901 ctggatgtgt atctcctttt ggatatgaga aaaatatctc tcttgtaata gatcaagata
    96961 tatttaacca tgataaaata atcttttcac cagggatacc agaaaagaca tttattatta
    97021 cagctagtgg atttaaaaaa gtaataaaca atataaacaa tacaacttat aaatatatat
    97081 attaatgaat tttaatcata attgtaaatt agagaaaata acattagaaa tcatgcttaa
    97141 ctatagtgta aataaattat attcaacaca aaagattgat actattatta caatagttac
    97201 tgttaagctc aaattcaatg tattatgagt tattattttt aaattttaat tacaaaagca
    97261 gggtagtttt aactactctg ctttatattt aacataaaat atataaaatc aacaaaatga
    97321 ttttagtcta tctattagat attcttcgct ctcaatgctt aaaactttta gatatataca
    97381 ataagtgctt tcatttgtaa aaatttctat agtattatct tgtttattta cacctacaat
    97441 atctttaaaa ttgatatgat ttttagtatt tttacatttg aaaatatatc tgttatcaat
    97501 caaaatctca tcattagtaa ttgaaatata gggtttatct catgctttat taaaaattta
    97561 tatgtttgct caagataaaa acttacaaat aataatagaa aagttacttt aaatgtacat
    97621 attatcgaaa atattatcac aaaaatactt ataatatata tttgtttaaa ataacctcta
    97681 tcgcaatagt ttattaacga tatggaaata aaagtgttaa atcagatttt ggagaaataa
    97741 ctttaaatat ttccagactc tttttagaca gcctccataa ccttatattg aacctattta
    97801 ttaactttgt acttacagat accatttata taagtttcgt gtatattaaa gtcattatct
    97861 gttactataa agtctgcatc cataccttga tatatagagc cacagacatt atcaatatta
    97921 caacttaaag cagggacata tgtagccatt tttattgcat cttctaaagt tgatatgttc
    97981 caatcaacta tatttctcac agccttgtcc atagttaata cacttccagc taaactccca
    98041 ctatttaatc ttgcaacact attttttaca tttacattaa acttaccaag agtatatttt
    98101 ccatcctcca tagcaccagc tctcatacaa tctgtaatta aagctatgtt attactagac
    98161 ttcgcatcca tcattatttt aacagctatt gggcttacat gatgaccatc acaaattaat
    98221 tcagcataag tatcttttag taccatagca gccccaacca ttccaggttc tctatgattt
    98281 aaaggactca tcccattata tgtatgtaca aacactttag cacctgaatt aacgacttgt
    98341 ttaacttgct caaatgtagc tgaactatga ccaagagaaa ctgatatatt atttttagtt
    98401 gcatatcttg ttaattctat tgaaccttta cgttctggag caattgctat ttttcttatt
    98461 aaatttttcg attttttttg ccataatttt aatatattga tgtcagggtc tttaaaatat
    98521 ttttcatttt gagcgccctt atatttttct gtaaaaaatg gaccttctaa ataaatacct
    98581 tgtatttttg caccctcaac tcgattgaag ctattgctta tattttctac agaatcactt
    98641 agtgtatcta cagaatcagt taaagttgta ggtaggaaag atgttactcc atattttaat
    98701 aagccttttg aaattgtgtt tattgcttca aatgtattgt ccatgacatc tgcacctaaa
    98761 agaccgtgaa tgtgagtatc aactaagcca ggagcaatat atttacctga aaaatctata
    98821 acattatcag taacattagg tctttcttgt tgaaattcac cgaatttgcc attaattata
    98881 ctaaggtaac ctttttcttt gattccatgt ttcataaaaa atttatctgc ataaataaaa
    98941 cttttcaaaa taacctcctt ataattatac tatcattgtg gcattgacgt ttataatatc
    99001 attctatttt cttgaaagtt atttaactta ctatcttaca tgtcttactc tatatacaaa
    99061 tttatcgctt ctagcaacac tcaaagtaaa ttcaataact atattgtcat cattatatgt
    99121 ggtacgaagt aatttcagac aaggtgaatc tcctggtact tccaataact tagcttcctt
    99181 atcagagatt attccagctg aaaattcttc atcagcaact ttaataatct cgccataatc
    99241 ttctctaaat atttcatata aaggtttttg ttcgattttt tcttttgtca atcctataaa
    99301 ttctttcata ggaagatatg ttctttcaag catcatagga aggtcatcag caagtcttaa
    99361 acgcattatt tttatcattt tttcaccagg agttatacct aatttttcag agaaatactt
    99421 tgtactttct actacctcaa atgataatac ctttgtacct ggcttttttc cttgtgttct
    99481 catataatct gtaaaactat aactttccat taagttttga gaattttgac ttagtgcagc
    99541 aacaaaagtt ccttttccat gtcttttgta tatatacccc atatgttcca actcagccat
    99601 agctagtcta actgtggttc tacttactcc atattcatca caaatttttc tttcggaaag
    99661 cattctatcg tttggttcca tctcattttc aatcttagtt cttaatatct caacaagctg
    99721 gtcatatatt ggtcttttat catttctttt tatcataaaa atatagtcct ttctaagtgg
    99781 ttattaccac aatttgatta tagaatatag aattatttat gtcaatgaat aaagtttaat
    99841 caaaattcaa taagtaaggt tattaattta ttataaaatt atggtacatt gacaaaacaa
    99901 gtaaaataat ttatattcaa attggtaata accactttgg gtatattata gatgaggtat
    99961 tttttatttt acagattaat ttattgttta gaaaagtaaa aattaataat gaggagaatc
   100021 tagtatgatt acagtaataa cattcaaccc atctatagat agaatgtata gagtgaataa
   100081 tataaacata ggtgaggtgc aaagggtagt aagtaagaat gcaactgctg gaggtaaagg
   100141 attaaacgta gctaaggtat gtaaaatttt aaaagaaaat cctttagcta tgggatttct
   100201 aggcggattt aatggagaat ttataaaaaa tgaacttaga aaactagata tacaaaataa
   100261 atttacaaaa atagagcagg aaactagaaa ttgcttaaac ataattgagg acaataaagt
   100321 tagtacagaa tttttagaaa aaggaccaat agtagaaaaa agcgatttag agagatttga
   100381 aaatgatata gaggaagtac taaaaaatac taaaatactg gtagcttctg gtagttattg
   100441 tgagaatatg ccgatagact attatgaaaa gataggaaat atatgtagag caaataatat
   100501 aaagtttata ttagatacat caggagaagc attaaaaata gctttaaaat caaaaccata
   100561 tttaataaaa ccaaatatag atgaaataag acatttatta ggaatgaata tagaatcaag
   100621 agaggaaatt atcttgtcag gaaaaaaact tattgaaatg ggtgcagaga atgtatgtat
   100681 atctttagga aaagatggta tggtgtattt aaacgaagat aatgtatatg atgtaaaagt
   100741 accagttgta aagtgtataa atactgtagg tagtggagat agcacagtgg ctggatttag
   100801 tgtaggtatt ttaaggggtt ataaaataga aaatttactt aaatttgcaa atgcttgtgg
   100861 tataagtaat gctttaaata tggaaactgg atttgtagat ttgggagaaa ttgataaata
   100921 tcaagattta gttgaagtaa aaaagttaag ttaaatacat ttaatgggaa tataataaat
   100981 ttaatgttgt tgtaatagat tttaatttta atataaaaga tatagtctta tataaaaata
   101041 ggttagaaaa attcattttt aacctatttt tataataaat atctatttta ctgaatttat
   101101 aattttctct agtaatcttt gagctttgat acactcttct ccattaatag ctggttttat
   101161 attattttct atacaatcaa taaaatgatt tgatatatcc tcaaaaccct tttgttttaa
   101221 tatatttacc catgcaccac tttgctttaa agttaggttt ccaccttctt ctatttccag
   101281 tacattaaga ttcttaactc tttgaatctt accctttgaa agaatttcaa cttgttctaa
   101341 ctttgttcca gaatctctat gcatagaggt gtttatagag aaatttttac ctttaagttt
   101401 atgacttaca aatataagat tcttattgtc tgttaaaaat aaatcctctc cactaatttc
   101461 aacatcttca tttgctaacc ataaagcagt gtcaataaca tgtatatagt catctataag
   101521 agtactgtcg aatctaacat ttcttaagga atttaatcca tgtttacata tattgataga
   101581 tacaatttct gtagcattat ttttaatttc tttgtacata ggacagaatc tacggttgaa
   101641 tccaaccatt aaatttaagt tttttttcgt acttaactcg ataagttctt ctccttgact
   101701 tactgttgaa gcaagaggtt tgtctacata tacatgaaca cctaaattta ataatatttt
   101761 tataatttcg tagtgtgttt ctgtagagct atgtagaaaa atacaatcac attttttagc
   101821 tagggattca atagaatcga atggcatgat tctataatca ctacagactt tttccctttt
   101881 aactttattt ggagtaaaag ctcctacaaa ctcaaatctc tcagacttag ttaatatagg
   101941 taaatatgcc ttttgagcta tggagccaag acctatcatt cccattttta tatttttcat
   102001 aatactttct cctaaggttt ttatatttac agaattgatt ataattcaga cacataaatt
   102061 tgtaaacttt gtatcaaaaa ataaatttaa agcttatata agtaaattag cgaaataaga
   102121 aatattgata aagtaatttt gtaggatatc cataaaattg attgatataa atattttatg
   102181 tattgacaaa aaattcaaat taatttatat ttggattagt ggtaattacc actttggtct
   102241 gaacaagctt ttatcgtaaa ataaaaatac taaagtatat agagtatgat tttattaaat
   102301 ttttaaagat aaactataaa attaattaaa atctatagtg tatattttat agtgagttta
   102361 agtagtacta aaaaatctaa gcaaaaaatt ataaaagagt atattttttt atagtttaaa
   102421 gtggttataa cctcattacc aaatgtaaac gttacaagta tgaaaggaga atgaaaatgt
   102481 ttaaattaga agaacaaaaa ctaaaagatt taggtgcaat aataacaact aatgaaataa
   102541 aacaacagcc tgaattatgg ttagaaactt atgaaatata taaatctaac aaagaaaaat
   102601 taagtagatt catagataca ataagtaata atcatgggca gtttagagtt atatttacag
   102661 gtgctggaac ttcagcttac ataggaaatt caatacttcc ttaccttaaa aataaaaatg
   102721 acataagaaa atacatattt gaagcaatac ctactacgga tatagtttca aacccatatg
   102781 attacttaaa aaaagatata ccaacattat taatttcatt tgcaagaagt ggaaatagtc
   102841 ctgaaagttt agcagcttta aatttaggga ataagattgt agataatttt tatcatttag
   102901 ctataacttg taatccagaa ggagaactgg ctaagatgac taaaaacgac gaaaataatt
   102961 acttgttatt aatgccatca aaatcaaatg atgaaggctt tgccatgaca ggaagttttt
   103021 cgtgtatgat gttatctgct atgttaatat tcgatagttt agaagatgat gtagaaaagt
   103081 catatataaa tgcaataatt gaaatgggaa gaaatgttat agatagaaaa gatgaaatac
   103141 atgagttaat aaataaagat tttgatagag ttgtatattt aggttcagga ggattaggtg
   103201 gtttgacaca agaagcacaa ctaaaacttt tagaacttac agcaggaaaa atatctacag
   103261 tgtatgattc tcctatgggg tttagacacg gaccaaaatc atttattgat gaaaatacac
   103321 ttgtatttga atttgtatct aactgtttat atacaagaaa atatgattta gatgttttag
   103381 aggagataaa aagggataaa attgctaaat tcacttgtgc agtgtcagta gaaaatgaaa
   103441 ataacttctc aggaacaaag tttgagttta aagaaaagta taataaatta ccagatgtgt
   103501 atcttgcaat gccatacata ttgtttgcac aaactatagc attgtttgta tcagtaaagg
   103561 ttggaaataa gccagatact ccatcagcta caggaacagt aaatcgagta gtaaaaggtg
   103621 taacaatata tgaatattaa aagataagat taaaatatta taactaaata atttgggagg
   103681 gtatcaatgt ggcattagta acaacaacat caatgcttaa aaaggcacaa gatgaagggt
   103741 atgcagtagg agcatttaat gtagaaaata tggaaatggt aattgctgtt atagaagctg
   103801 ctgaggagtt aaattctcca gtaatattac aaactactcc atctactgta aaatatgcag
   103861 gtcttgatta ttatctagca aatgcaaagg ttgctgcaga aagagtaaat atacctgtag
   103921 caatgcatct ggaccatggt tcaagttttg accttgcaat gaaagcttta agaagtggat
   103981 atacatcaat aatgatagat ggttctcatg aaagctttga aaataatata tctatatcta
   104041 aatcagtagt aaaagcatgt agtccttctc ttataccagt ggaagcagaa cttgggaaag
   104101 ttggtggaaa agaagatgat ttagatggcg ggaatagtaa tgattataca aatccaaaag
   104161 aggcaaaaga gtttgtcgat agaacaggaa tatcttcatt ggctattgct ataggtactg
   104221 cacatggatt gtataagggt gaacctaaaa tagatttaga taggttatca gaaattaaaa
   104281 atgtagtttc aataccttta gtattgcatg gaggttcagg aatacatgat gatattataa
   104341 aagaagctat aaaaagaggt attgcaaaag ttaactatgc aactgaatta agaattgcat
   104401 atagtaaagg ggttaaaaaa gttttagatg aagattctga ggttatagac cctaaaaagt
   104461 atggattagc agggcttcaa tcagtaaagg attttgtgaa agaaaagatt aaagtgtgtg
   104521 ggtctgtaaa tagagtataa aaataaaata tcctaaattt attttagata agtttaggat
   104581 atttattata tgaaaaattt atattaatta tatgtaaatg gtgtattttt ttcatttaat
   104641 tgatgaaa
//
LOCUS       DAMJWC010000005        93465 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMJWC010000005 DAMJWC010000000
VERSION     DAMJWC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 93465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93465
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.005"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(777..1286)
                     /locus_tag="PC503_000459"
     CDS             complement(777..1286)
                     /locus_tag="PC503_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2526479.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1497..2906)
                     /locus_tag="PC503_000460"
     CDS             complement(1497..2906)
                     /locus_tag="PC503_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2526480.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2910..4040)
                     /locus_tag="PC503_000461"
     CDS             complement(2910..4040)
                     /locus_tag="PC503_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2526481.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(4052..4855)
                     /locus_tag="PC503_000462"
     CDS             complement(4052..4855)
                     /locus_tag="PC503_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526482.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESALKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5237..6118)
                     /locus_tag="PC503_000463"
     CDS             complement(5237..6118)
                     /locus_tag="PC503_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF2526483.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6574..7548
                     /locus_tag="PC503_000464"
     CDS             6574..7548
                     /locus_tag="PC503_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526484.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(7664..8725)
                     /locus_tag="PC503_000465"
     CDS             complement(7664..8725)
                     /locus_tag="PC503_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2526485.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(9337..10188)
                     /locus_tag="PC503_000466"
     CDS             complement(9337..10188)
                     /locus_tag="PC503_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2526486.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10205..11125)
                     /locus_tag="PC503_000467"
     CDS             complement(10205..11125)
                     /locus_tag="PC503_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF2526487.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIKGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11235..12149)
                     /gene="murQ"
                     /locus_tag="PC503_000468"
     CDS             complement(11235..12149)
                     /gene="murQ"
                     /locus_tag="PC503_000468"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF2526488.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12248..13345)
                     /locus_tag="PC503_000469"
     CDS             complement(12248..13345)
                     /locus_tag="PC503_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2526489.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(13578..14924)
                     /locus_tag="PC503_000470"
     CDS             complement(13578..14924)
                     /locus_tag="PC503_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526490.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(15013..15321)
                     /locus_tag="PC503_000471"
     CDS             complement(15013..15321)
                     /locus_tag="PC503_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526491.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15584..15982)
                     /locus_tag="PC503_000472"
     CDS             complement(15584..15982)
                     /locus_tag="PC503_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526492.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(15984..17144)
                     /locus_tag="PC503_000473"
     CDS             complement(15984..17144)
                     /locus_tag="PC503_000473"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF2526493.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17575..18594)
                     /locus_tag="PC503_000474"
     CDS             complement(17575..18594)
                     /locus_tag="PC503_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2526494.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLIKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(18588..19268)
                     /locus_tag="PC503_000475"
     CDS             complement(18588..19268)
                     /locus_tag="PC503_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526495.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GVGYIIQC"
     gene            complement(19420..21327)
                     /locus_tag="PC503_000476"
     CDS             complement(19420..21327)
                     /locus_tag="PC503_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2526496.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAMFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(21328..22080)
                     /locus_tag="PC503_000477"
     CDS             complement(21328..22080)
                     /locus_tag="PC503_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526497.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22396..23550)
                     /locus_tag="PC503_000478"
     CDS             complement(22396..23550)
                     /locus_tag="PC503_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2526498.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(23553..24020)
                     /locus_tag="PC503_000479"
     CDS             complement(23553..24020)
                     /locus_tag="PC503_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2526499.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(24034..24522)
                     /locus_tag="PC503_000480"
     CDS             complement(24034..24522)
                     /locus_tag="PC503_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526500.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24536..25867)
                     /locus_tag="PC503_000481"
     CDS             complement(24536..25867)
                     /locus_tag="PC503_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2526501.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25881..27446)
                     /locus_tag="PC503_000482"
     CDS             complement(25881..27446)
                     /locus_tag="PC503_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2526502.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27616..28401)
                     /locus_tag="PC503_000483"
     CDS             complement(27616..28401)
                     /locus_tag="PC503_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2526503.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28568..29767)
                     /locus_tag="PC503_000484"
     CDS             complement(28568..29767)
                     /locus_tag="PC503_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF2526504.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(30289..31626)
                     /gene="xylA"
                     /locus_tag="PC503_000485"
     CDS             complement(30289..31626)
                     /gene="xylA"
                     /locus_tag="PC503_000485"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF2526505.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(31722..33272)
                     /gene="xylB"
                     /locus_tag="PC503_000486"
     CDS             complement(31722..33272)
                     /gene="xylB"
                     /locus_tag="PC503_000486"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF2526506.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVSSLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSKVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            33480..34640
                     /locus_tag="PC503_000487"
     CDS             33480..34640
                     /locus_tag="PC503_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2526507.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34796..35200)
                     /locus_tag="PC503_000488"
     CDS             complement(34796..35200)
                     /locus_tag="PC503_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2526508.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNANLLSDDE"
     gene            complement(35221..35703)
                     /locus_tag="PC503_000489"
     CDS             complement(35221..35703)
                     /locus_tag="PC503_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526509.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(35723..36532)
                     /locus_tag="PC503_000490"
     CDS             complement(35723..36532)
                     /locus_tag="PC503_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2526510.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(36525..37304)
                     /locus_tag="PC503_000491"
     CDS             complement(36525..37304)
                     /locus_tag="PC503_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526511.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(37304..39382)
                     /locus_tag="PC503_000492"
     CDS             complement(37304..39382)
                     /locus_tag="PC503_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF2526512.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(40181..40702)
                     /locus_tag="PC503_000493"
     CDS             complement(40181..40702)
                     /locus_tag="PC503_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2526513.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            40868..41434
                     /locus_tag="PC503_000494"
     CDS             40868..41434
                     /locus_tag="PC503_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2526514.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(41651..43714)
                     /locus_tag="PC503_000495"
     CDS             complement(41651..43714)
                     /locus_tag="PC503_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2526515.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYSNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(44095..47430)
                     /locus_tag="PC503_000496"
     CDS             complement(44095..47430)
                     /locus_tag="PC503_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2526516.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMMDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTENFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(47480..47908)
                     /locus_tag="PC503_000497"
     CDS             complement(47480..47908)
                     /locus_tag="PC503_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526517.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(47898..48278)
                     /locus_tag="PC503_000498"
     CDS             complement(47898..48278)
                     /locus_tag="PC503_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF2526518.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(48311..49483)
                     /locus_tag="PC503_000499"
     CDS             complement(48311..49483)
                     /locus_tag="PC503_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2526519.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVEVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGEPINNTKKFDMKKIKEISIYLKRGVSPKYVEQSN
                     IKVINQKCIYWRNLKVENCKYYDENLKEKIEDIFLKQNDILINSTGTGTLGRCVKFNK
                     IDNSEYIADSHVTVLRSISNNLNSDYFAALFEFTNIQDTIYRKCVNGSTNQIELSVSK
                     LGEYLIMVPPIEFQNQFSEFVKQVDKLKLKIETNLKELEDNFNSLMQKAFKGELFN"
     gene            complement(49487..50950)
                     /locus_tag="PC503_000500"
     CDS             complement(49487..50950)
                     /locus_tag="PC503_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2526520.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            complement(51460..52329)
                     /gene="gatY"
                     /locus_tag="PC503_000501"
     CDS             complement(51460..52329)
                     /gene="gatY"
                     /locus_tag="PC503_000501"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2526521.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(52349..54265)
                     /locus_tag="PC503_000502"
     CDS             complement(52349..54265)
                     /locus_tag="PC503_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF2526522.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVAKLNNEEIKSV"
     gene            complement(54268..55188)
                     /locus_tag="PC503_000503"
     CDS             complement(54268..55188)
                     /locus_tag="PC503_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF2526523.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(55290..56042)
                     /locus_tag="PC503_000504"
     CDS             complement(55290..56042)
                     /locus_tag="PC503_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2526524.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(56434..57879)
                     /locus_tag="PC503_000505"
     CDS             complement(56434..57879)
                     /locus_tag="PC503_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2526525.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(57901..58254)
                     /locus_tag="PC503_000506"
     CDS             complement(57901..58254)
                     /locus_tag="PC503_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2526526.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(58283..59530)
                     /locus_tag="PC503_000507"
     CDS             complement(58283..59530)
                     /locus_tag="PC503_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526527.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMETMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(59538..59855)
                     /locus_tag="PC503_000508"
     CDS             complement(59538..59855)
                     /locus_tag="PC503_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526528.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            60097..62010
                     /locus_tag="PC503_000509"
     CDS             60097..62010
                     /locus_tag="PC503_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2526529.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGAFILSSKKGYKVNLNTNCQTKIDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLVGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(62133..63287)
                     /locus_tag="PC503_000510"
     CDS             complement(62133..63287)
                     /locus_tag="PC503_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF2526530.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEKLDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLDSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(63566..66181)
                     /gene="mngB"
                     /locus_tag="PC503_000511"
     CDS             complement(63566..66181)
                     /gene="mngB"
                     /locus_tag="PC503_000511"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2526531.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPDRKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLIAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEDWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(66325..68250)
                     /gene="mngA"
                     /locus_tag="PC503_000512"
     CDS             complement(66325..68250)
                     /gene="mngA"
                     /locus_tag="PC503_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF2526532.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIDDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(68380..69105)
                     /locus_tag="PC503_000513"
     CDS             complement(68380..69105)
                     /locus_tag="PC503_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2526533.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(69368..70147)
                     /locus_tag="PC503_000514"
     CDS             complement(69368..70147)
                     /locus_tag="PC503_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF2526534.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(70140..71567)
                     /locus_tag="PC503_000515"
     CDS             complement(70140..71567)
                     /locus_tag="PC503_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2526535.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            71958..72680
                     /locus_tag="PC503_000516"
     CDS             71958..72680
                     /locus_tag="PC503_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2526536.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            72877..74544
                     /locus_tag="PC503_000517"
     CDS             72877..74544
                     /locus_tag="PC503_000517"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF2526537.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(74640..75959)
                     /locus_tag="PC503_000518"
     CDS             complement(74640..75959)
                     /locus_tag="PC503_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2526538.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(76000..76746)
                     /locus_tag="PC503_000519"
     CDS             complement(76000..76746)
                     /locus_tag="PC503_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2526539.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(76990..78999)
                     /locus_tag="PC503_000520"
     CDS             complement(76990..78999)
                     /locus_tag="PC503_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526540.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(79437..80870)
                     /locus_tag="PC503_000521"
     CDS             complement(79437..80870)
                     /locus_tag="PC503_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2526541.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(80957..82873)
                     /locus_tag="PC503_000522"
     CDS             complement(80957..82873)
                     /locus_tag="PC503_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2526542.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQILITFDIESISKEGYCLETPVVVTNYSDYVDILENTQ
                     KHVNNSQELITVLA"
     gene            complement(82947..83807)
                     /locus_tag="PC503_000523"
     CDS             complement(82947..83807)
                     /locus_tag="PC503_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2526543.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(84158..85345)
                     /locus_tag="PC503_000524"
     CDS             complement(84158..85345)
                     /locus_tag="PC503_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2526544.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(85359..86750)
                     /locus_tag="PC503_000525"
     CDS             complement(85359..86750)
                     /locus_tag="PC503_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF2526545.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(87345..89045)
                     /locus_tag="PC503_000526"
     CDS             complement(87345..89045)
                     /locus_tag="PC503_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2526546.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(89017..90420)
                     /locus_tag="PC503_000527"
     CDS             complement(89017..90420)
                     /locus_tag="PC503_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2526547.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(90684..91175)
                     /locus_tag="PC503_000528"
     CDS             complement(90684..91175)
                     /locus_tag="PC503_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2526548.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(91201..92013)
                     /locus_tag="PC503_000529"
     CDS             complement(91201..92013)
                     /locus_tag="PC503_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2526549.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(92026..92985)
                     /locus_tag="PC503_000530"
                     /pseudo
     CDS             complement(92026..92985)
                     /locus_tag="PC503_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(93103..>93465)
                     /locus_tag="PC503_000531"
     CDS             complement(93103..>93465)
                     /locus_tag="PC503_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2526550.1"
                     /translation="QKLSTKLIKENDIICIEDLQVKNMIKNRKLSRSISDVSWSEFIR
                     QLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDIN
                     ASINILKEGLRLITIQNK"
BASE COUNT        30253 a        16788 c         9820 g        36604 t
ORIGIN      
        1 attttttatc ttaatcttct gaatataagt gaatgctatc attttaagta tcttataagc
       61 aatgtaacta tatatctcta ataactactt ttttaacatg cttaaactat ttataagcta
      121 ttatatttat gtattaacct aataactttt tcactaaaaa ataacaatct attcaaagat
      181 aaactatagt acttcttcta ctttgtttca ataaaatact aaataaattt cgtacatcca
      241 caatttttca ggctacacta taaatataca atatttatct tagttataag tttaagaata
      301 tttttagtct tattttgtcg aatatctttt taataaaact tcataattct aagcatattt
      361 ttacactgtg ttttcatgta caaaaataat gcttacaaat aaacaacata aataaaactt
      421 aaataagatg gattctattc aacatagtat ccatcttatt cattcaaaac ctaaaaggat
      481 tttttataat attatatatt ttaaaatcta agtaactcat tatagtatca atttcactta
      541 aagcttacaa tacacttatt aatcttgttt tatattaaaa acatctacaa taacaattta
      601 aatctttaag tgatatccat ctcacaccta aaggagtagg ctctccgcac tattctgtaa
      661 ttcttcaata caatcattat tattttttat ataatttaat tatatatttt attttaccaa
      721 aaccagcata cataaataat acttaaaata gattaaataa aggatactaa aacactttat
      781 tgaggtatat gacttgaaat atatgaacta acttcattag gagaaatatc taaaatagtt
      841 gcaaattctt catttaataa cctttcagct tctttcatta tattatcatc tgcttgatgt
      901 gtttttttac caatagattt tacatactct ctgttattat ctatacttct tactaatttt
      961 attaactctt cacatttacc acctctgagt atttttttaa attgctcact tctcaatttt
     1021 tcattatcta tccatgatgt atccatatta ggaatatcat ttattaatga aagcacatta
     1081 attttagaaa gtaactttct cattggtact ttttcattat ctacaggaat ttttattact
     1141 gtattattag aataaatagg actcaataca taatactctt tttttattcc atttgtaaat
     1201 cgttcatttg ttatatccat gactttgcag actcctgtca taccatacat tatataatca
     1261 tcaatcttaa acaaaaacat caccatcctt aataaaaaaa atagttttga caactaaatc
     1321 caccttgcca aaactatctg ctatatatta tattttaaca cattttgaga cttaaatgta
     1381 agtaaaactt atattattaa aattaaaaaa tacattaacc attgattaat gtatttttta
     1441 gatttttata acaagcatat caaaataaat taatacagct tatctcctgt gaatacctat
     1501 aaaattggtg cttggctatt cattgagtac ccatcatttc ttacatcatt tatttctaat
     1561 atttcatcat ttgttttaac cttagtaagt tttttaactg ctccataagg ttcttttaat
     1621 gaaattttat ctcctcttcc agaaataacc cataaaattt tgtaccctct aggtattact
     1681 tgtagtttat tttcaccttt accatcagta aagtagacta acaaattaat ctttttatta
     1741 ttagcatact caaagactgg agaaaatcta gtacctccac ctatcctaat tctatctttt
     1801 atatcttttt cagttctcac tttatataca cgtctaattt cattatcaca ttctataatt
     1861 gtaatttcat gattatagtt tttcactata ctaagaactt ctttaatagc ttgtttaaac
     1921 tcttcatcac taatacttcc acttacatca agtgcaactg ctatttctga cttatgactt
     1981 ctaagttctc ccctcaaatc taaacgattt ggttgtcttc tatttcttct tgttatagtc
     2041 ttctttttat tattttcaac tgttcccatt attctattaa gatataaatt ccatggcaat
     2101 tcacccttac tatttttaag tgatgatatc atactttcta aataagcagg aactttacct
     2161 ttttgagaac tgttaataaa tttttcagta aattctctaa gggtattttc atctatctca
     2221 ttggattcat cccatatatc atgagttctt tcggggctat aatcaatttc tatatctcca
     2281 tatttatcac tatcatcttc ctcaccatct tcatccactt ccatcaaatc taattcagtc
     2341 tgaatctttt ctacataata ttcaaaaggt tcatatggtt caagttttaa ggaatatttt
     2401 aaatttaccc actctaaggt agttgcatat ggtggtaaat tgtttagaaa tttatttact
     2461 actatatcca ttgccatatt aattgctaat gtactatact ttccttttaa ctcctttgct
     2521 ctcatcaaat gcatagataa tatatgatga atttcatgtt taattgtagt ctccatttgc
     2581 tttatgtcaa gcgttaaaaa gattattgga ttaaaatata taatatattt agctccctta
     2641 aaattcacac ctgtaggact acttatatca aatcttattt ctcttgacat ctgaaacaaa
     2701 aaatatccat aaaaattatc ttcttcttcc ataagactta aattcacttt atctacaaga
     2761 ctaaaaaact catacttaaa atcttgtggt atatctatat caaatttctc attagcacga
     2821 tttgccttta gcatagaatg agtatttata atttcacttg ctttattata aagctctttt
     2881 gcttgtttat caaaataatt ttccatacat tatcccctta ttaaactata agattcaaaa
     2941 tatgatttta caaactcttc attttctata gcttttttat atacttcaat ataactgttt
     3001 ctaatatcct tcataatacc tatcattaaa tctacaggat acatttttaa aaattcaata
     3061 aatctattaa tatagtggtt tgattcatat ttatcattct taatatttaa ttctaagtct
     3121 tttagaatgt tcatagctga tagataaagt cttgtatgac tctcattttt tactctttct
     3181 acaatagact catcaataga ttctcctaaa aaaacatctt cataggatat taatggttca
     3241 gagtttgatt caataaaact tataaattct tctgcaataa ctttacctac attacccttt
     3301 acaacattta aaaatactgc tctaggaata gaattatttt tttctttata aactttataa
     3361 attttagata ctctctcata acttctagga gtggctctta catcatcttc atttatttta
     3421 tgcagatatt ctggaaaagt ggaaataaac tcgataactt ttctttcaat accctcatct
     3481 attgcccatt ttatccattg tgtatggtca ctctccatat ttaaccaaac aaacctattt
     3541 tcttgggctg catccatatc taccacttga taatcaaaat ctgaaccata tttacttgat
     3601 ggattcattg ctgctaaaat ctttacatca tcatgcagtt tatatccatt aatttctcta
     3661 tttaaaatta aattcataag ttcttgctgt actgtatgct cacaacgatt tatctcatct
     3721 ataaataaaa gaactgtctt acttttagat atctcttcat caatttctct taatttgtta
     3781 tgaacagcat acactgttgt tttcttttca gtcttatatc cattagaatt aactcctaca
     3841 taagattcta tagttggaag accacctatt tcaccctctt taagtaagtt tccatcaata
     3901 acaattaaac tccaatcatt ttctttggca agcttatttg ctaaagctgt ttttcctatt
     3961 ccactttcac ctactattaa aggtacttct ccagtggata atattaagtc aacgcttttt
     4021 aatgtgtcta taaaattcat ttttctctct cctacataat ctttaatttc tcatctacag
     4081 ctattttttt tgctgtctta cttccatatt tataaataaa cataatttta tctattggta
     4141 tactttcgct atttctatct ataacactac aattcaaaaa atctctaata tacttttcct
     4201 caacatcttc tttggataat acttctttta atgcactctc taattcatct ttagatactt
     4261 ttttcagaat gtacttaatc actaaaatat tcacttttaa aaattccaac attttatttt
     4321 tatctaaatc agttataaag ctaatagctg cttcattatt ttttatagct ataagttctg
     4381 cattataact aggtgaatct atatatctca aggcatcata acttattctc actgcctcct
     4441 cttgtacact ttcataaggt tgttttataa actttatcga atcataattt tttcttactg
     4501 ctaacagttg taattcttca cttggatttt tagcatattt aattgcccat cctgcttgat
     4561 ttatagccat ttcaataact ttatcagttg ggtttttgat ataatccagt atactccatc
     4621 cctcatttac tgcttttatc atcatatctt ctgttggatt atctataaat ttaattgctc
     4681 taatattatt atctattgct agttcttgca tctctctggt tggattattt atatattcta
     4741 gtacaagccc attttcttta atagctaaca atttcatttc atcagttgga ttatctattg
     4801 tagctataat attgggatta ttttttatca tttcaataac tctcaatttt tccataatgt
     4861 gcctttcctt ctataattat ttttatatct atattaatta taataatcta ttcctattta
     4921 tataattgtt tcttattata attaatatac tttttaatca aatttaaaca gaataattat
     4981 accaatatat aaaaaaattt ctaaaaaaca ataaaattaa gttataaaca ccaatatatt
     5041 tctattattt caataagtat acaattagat tagaatctaa cgctagtaat aaaaaattac
     5101 tttcccaaaa tagatataag cctcatttta tcgttcaaat aatgaaaata tatttgattt
     5161 catgcaaaaa gagtgcctaa tgaactaaaa agttcatttt gagacactca tttttttata
     5221 taaatttata tagtttttaa tcgttcgcat tcaaccactc agttaagact tttatatatt
     5281 tctcattttc ttcaacgaat ggcatatgtc ttgaatactc aaataattcc cacttactat
     5341 taggtattct atcatacata gtctttgcaa tatatggtga acataaatct attgctccac
     5401 tagttactag acaaggctct tttatttcat gtaatctatc tgtaaattca tatccagaaa
     5461 gagttcctgt aggagaaaat tcattttgtc cccatcctac aatatatgct tcagaacctg
     5521 attttttagg tcttctcagg cactctggag aatcttctgt cacttcacct gcacaataca
     5581 tttccataaa tctttctaat gcatcattat attctttgct agagtaatct ccagtattta
     5641 ctgcatcaag taatgctttt tggtcaacct cactcatata tgatattctt cttttttgtt
     5701 ctttctccca aagttttgca gaagaaagag tagatgaaag gatgtaagac ttaatacctt
     5761 ttggtttata ttcaatagca taccaaatag cctgcatacc tccccaagat tgacctaaca
     5821 gatgaatttc atcaagtcct agatgttttc ttagttcaat aagctcctct atccaagtat
     5881 ctgcattaaa tagctcagga tgcccttcta caaatgaatt tccacaacca atttggtcat
     5941 acattattac ttgtctacca ctttcagcta tcttatccaa tacctcaaaa tagttgtgtg
     6001 tagaacctgg acctccatga agtaatacta atggcttctt cccttccgta ttttctccta
     6061 ctatacggta atacgtttta aaacctttaa aaggcatata tccttcagta attttcatgt
     6121 ttatctcctc caatttgtaa ttataaacaa taatcaagtt cattaacaat actatttaaa
     6181 acctcttata catatttgat tatgtatttt aatctttata cctactttta taaatagtat
     6241 aacataaaag ttaaaaatct ctatactaaa ccaattataa aattatatta actatataat
     6301 tttatttttt aataatagta tatacatatt tgattatttt catttgctat ttaaaatcaa
     6361 ttttaagttt tcttcttata ataaacttcc tctttgtggt ctcatgttag tctctaaatt
     6421 taaaatttta caaaaaattt tcataaaata aaattatatt gattgtatct aaacaaatag
     6481 ggcaataaaa taattaagta tagttactta cctttcaagc aatattagtt ttatgttaga
     6541 attttattat attgatttac aggaggtttg catttgaata atattaattc acttaaagta
     6601 ataaaattat ctcttggatg ttctcttgct atatttattg cttggctatt aaaattagaa
     6661 tattcaatgg ttgctggagt tatagtacta cttacagtaa aggacactaa aagagaaact
     6721 cttaaaggct ccattggaaa gatttatggt tttcttttat gtactatttt ttcatattta
     6781 tgttttaata ttttaggata taatttgact tcattttcaa tatttatatt tataattata
     6841 ccactttgtt ttttgttaaa tattcaagat gttattgcta tgtgtgtagt catagcatcc
     6901 cattactacc ttcaaggaga aacttctatc aaatggattt taaatgaagc tggaatattt
     6961 gcagtaggaa ctggaatagg tgtcttaata aatatgtata ttccaacaaa tatacataaa
     7021 atccatgaag ttcaaaaaaa gttacaggaa gaagtgagta ttgtacttat agacattgca
     7081 gatattattg taaatcctaa aaaagaaaat ggatatagta gagatttata tacattaaat
     7141 tcacttattg acagcagtat ttctgaaact tacgataata ttaataatac tttattaagt
     7201 gatactagat tcttcttaga gcatatggat attataaaaa gtcaacggga tatcttagaa
     7261 aatttgtata gttatgtatc tcaactaaat tctacaccac cacaagctca tattctatct
     7321 gcttttatac ataagatagg ttatactgaa tttgaagctg aaacaggcaa tcttcttctt
     7381 gaagaattaa agagactaat gcttagtatg aaaaaccagc ctctacctgt tgacagaaca
     7441 gagtttgaaa atagagctat tttattccta tgcttgactg agttaaaaca gtttttagtt
     7501 aatcgtaaac atgctcagat gcttagagat aataattttt ataaataaaa aggggagaaa
     7561 tctagcagtt gacctgacta caaaatatca gatataatat taaatgcgcc cctagtaaga
     7621 gggcgcaatg tttataactt attctactgt catgattaaa tcattattca tatcgaacat
     7681 acattatttg accaagtcca atattagctt tttcatcagt gatttctatt ttaatagtca
     7741 catcattttt tttacagtac ttcgctaatt ctgcaccaga acgattttta ccactaaaat
     7801 ctaaagaaaa tggcttatca tatttaaaag gatattcaac aggtttaccc tctggtgcta
     7861 atgcaaacat cccatatggt gtgttcataa atcctattac agcaatcgta agatttgatg
     7921 ggtctaaatt tgattcacta cctgtaaatg taattgtatt tactgatgaa ttaactacac
     7981 tacatcgaac accttcatac attacatgtt tttcatttat atcttctcct tttttcccaa
     8041 aatttccaac agcctttgcc ccttcttgat gtggtaacat agtgtgcttc ccaggtggtg
     8101 ctggtttctg tgtctgttct ggttttaccg tctgtactat tgcaccaact tttggatatg
     8161 ctgtcttatc aaatggtaat gggtggctaa gactcttgta tatgatatcc tttcctgctg
     8221 atttattagc atcaatatct acatgataca aacgcccatc accaaaacgg ataagattcc
     8281 actggtggtc atttgatgtg ctgtgtacat aataagattc aattcccata gcatcacaca
     8341 aagctttcat gctcctagcc attcctgagc atgcaccttt tttagtaacc aatgtatagg
     8401 cagtatttgc tccctctact gcattccagt caacatatgt tgtgttattt ttaatgtgat
     8461 tgtaggcaac taaaatctta gcatctgtgg tcatattctt tgtgattttc ttgttcataa
     8521 aatctgctgt tgcttgtgct actgagttta gttgggcttg tgacagcttt ggaccatata
     8581 cgctattggt tccagtgaca tagctttttg gtgtttttgc tgttacctct ttggctgtca
     8641 taccataaac tgtcatactc atacctgaga ttaaaactat tgttgtaatc aataacttgg
     8701 tagctaactt cctaattttc ttcatactta atattctcct ttataaaaca ttgttacttc
     8761 ctattctcta ccattaataa aattaattta ggatttaaaa aggtggattg tcaacatgta
     8821 tatttctcca ttcatacatt cgtgaaatat ttaaatttca tggaaaatct aatagatatt
     8881 ttctagataa tttgtataca atacaactcg caaatcaggg tgtttgctgt tagtttgaga
     8941 aaatgatgat gattaataca ttcggaatct ttgacctata ataaatacca ttgtcttcaa
     9001 tcattaataa tggtaagagt aaagagaatt atcaataata cagttaaaat caactttgta
     9061 tacatttcat acattctctc ccaacaacat tatacttctt ataatttgta tattcaatac
     9121 gttttctggg aaaatatagg atatatctat aaaaatataa aaaaggagtt gaacttaaaa
     9181 tttgattaaa aaaaatcaat tttaagacaa ctcatttgta ttataaaaat gctatatatt
     9241 attattaagt aagtcaatat tttagatatt tatctatttc ttattgactt acgcttatag
     9301 tctaacttat ttgtttagtt gatatataac ctagttttaa gcattattaa tatttaaata
     9361 atcaagtatc ctttttgttt cttgtagttt ctgttctgcc tcatttaagt tttcttgaat
     9421 tatagaaata tatattatat ctatcaacgt aagcattgct attcttgaag aaatagctcc
     9481 ttctctaagc cttttttcta tatttggtac tactagtttt aaatcactaa tcttactaag
     9541 atgattgtca ctatatttag ttatacaaat gaccttacat ccttttaatt ttgcattttc
     9601 tatagacttt attacttctt ttgattctcc agagtaagat attgctatag ctatatcttc
     9661 tttatctaca tttgaagata ccataagttg tgtatgacta tctaaagagg taaatgcctg
     9721 tttatttatc cttaaaagtt tcatctgtaa atctagtgca actaaagccg aaccacctac
     9781 tccaaatata tatacatttt tagcctttat tatctgttca actgcttctt ttattatatc
     9841 tttttcattc aacaaccttg tttggttgat agtctctatg tttttgtttg taattttgtt
     9901 tataacacta tctatattac aatcatagtt ttcatctaca tatgtgtatt cattttcttt
     9961 gcccatcaaa tctttagcta tctcaatttt taaatcccca aaacccgaat atcccatttt
    10021 tctagaaaac ctaactatac ttgctgtact tgtttttgag tttgacgcca attctgatac
    10081 agaaagctta cttatagcct ctgtattatt aagtatgtaa tcagctattt ttttatctac
    10141 ttccgttaaa tcttcatata tctgttttaa ttttaaaatg caactcatac tctatcacct
    10201 ctacctattt actataatat ttcttcttag caagtaaaca tgctcctaaa tctggagtca
    10261 acactggtct cactatacca aatctcgttt tattcaaata ttttttaagt ggctctaata
    10321 ttaaatctcc tgacttaaac actccacctg aataagatac ctttatcttt gtaccttgtt
    10381 caaaatgatg ctctaatcct attataagcc tacttaattc ataagctgca tcatcaaata
    10441 ttttactagc agtattatca ccttcaataa ctgcttttaa acatatcgta gcaaactttg
    10501 ctatttctat tctatctcct tttatttcat catttacata ttttattatg tcataatcat
    10561 tctctatatt aagatgtctt tttattaaat catataattt tgtttttgaa caccttccat
    10621 cagactgcat tgtgaacatt tttaaggtag ccattcctat ataatacgct gaaccttcat
    10681 ctcctaatac atagccccat cctccacatc tgtgaagatt cccatcttta tctaaagcct
    10741 gtgctattga accagtacct gcaattatat ttataccttt ttccccattt aaagaacctg
    10801 ctaatgctat ttctacatca ttacctagag tataatttat atgactatat gcattttttg
    10861 ttgctacttc taatgcatac aatacttctt ttatttttcc atatccagca agtccaacaa
    10921 atgcatacgt tatttcttct acatttatct tagcatcttt acaaacttct tccaacccag
    10981 ttattaataa tttcgttaga ttatcaaatc ctatttgatt ataatgacaa gttcctttgg
    11041 ttatggttcc tactatattt aattcttcat ctactaatgt aaatgttgtt ttcgttcctc
    11101 caccatctac acctaaaaaa tacatactat cctcctacaa tatctttaat aattctttca
    11161 atacttaata tctaaaaata accttccaat gctgtttttt taatattgaa aggttatcag
    11221 tactattatt tattttacaa tttttctatt gattttaaag cttcacttat ataaccttct
    11281 tgtctatcta ggatactctt tgcactatcc ttatctaaac cactttttat cataaatata
    11341 gccaatttaa cgctattatc tgcttcttct aagaattttt ctgcaacatc atattttaca
    11401 tttgtagcta tcattattat tctttttgct ctttcaacca acttttcatt tgatgtctta
    11461 acatctacca tcaagtttga gtatactttt cccatcttaa ccatagaagc tgttgttaac
    11521 atattacata ccattttttg agctgtacca cttttcattc tagttgaacc cattattact
    11581 tctgccccta ctataatgtt tattggtaaa tccgcttttt tactcatttc actattcgga
    11641 ttcatagtta ttgatagtac tgcacacccc aattccttag catactccat tgcacctata
    11701 acataaggag tccttcctga tgcagctata ccacatataa catccttaga tgtaactcct
    11761 ctatctatta tatcttgctt tccaagttct ttatcatctt cagcaccttc tattgcttta
    11821 aatattgctt gatttccacc agctattata gcttgaacaa gctcaaaatc cactccgtaa
    11881 gttggaggac attctgtggc atctagtatt cctatcctcc cactggtacc tgctcctata
    11941 tagaataatc tacctccctg tttcattcta tctactatta tattaacagc ttttgctata
    12001 ctctcctttt gttcttcaac agcataggct acagttttat cttcgttatt tattaattct
    12061 attatgccta atgtatcttc tttatctatt tgcaatgtat tcttatttct accttctgta
    12121 actaaatttt ctaaagtttt tattaacata tcatttcctc attttcttaa tattaaattt
    12181 ttaaacacat tttaattcca actttcataa ttatattttt ataataaatt aatattttca
    12241 taataaatta ttttgttgag ggtttaaaat taaacttttg ccatggttta atataatcta
    12301 atataaataa ttcttctttt cttatatatc ctactacatt cgatttacca ctgtttttca
    12361 tatcagtcaa ggctatttgt aactcccctg cataatgacc atattcacta ctttcaatta
    12421 ctatatctcc tctttttatt attttaggag tattaaatag ttcaaattta tatcctttat
    12481 atttaacacg agattgagta gaccttatca gactatcaga tatgtcccct ctattaaaat
    12541 gtatttcttc aaagagtatc ttcttctcaa cttctcgtat attttcctct attgctacat
    12601 caaatgtaac catatctttt ctcatagaac ctaatacctt tagctcctca tatgttggat
    12661 aacaatttga tattattata tcatttatat tattcatagc tattatatgc tttacttgaa
    12721 tatctatagg tagatttctg tgcatctcaa ttgttggaag cccatcagtt acaggccatg
    12781 gtccaaatgt agtttcattt tgacttgtta caaaaactgc tgttcttaat ccatacttat
    12841 taaatctttc tgtacatttt ataaagtgtt ctaaatttaa tccactatat ctatgtggat
    12901 aaaagttatg acatcctatc aaattttctt tatttggttg gtagtccatt attgtatcta
    12961 tataattagt attattactc atattgattt ctattttaag attttgagga ttaaaagtca
    13021 ttaatgcctc ttcagaacct gtaaatccca tatcaagcct tattccgtct gccttcgtct
    13081 ttttaaaaaa attcaaatct ttgtagctta tttctaattc accaaatact ctgggattta
    13141 catcaagtat tacctcaaaa cctttaaact tagcgtattc atttatactt ttaaattttt
    13201 taattatatt ttctttagta tctttaactg ataataaaca tgaaaatata cgtgtaaatc
    13261 cattttcagc agctttatct atataatcat atatttcctt agatgttgtt ttttctggat
    13321 aaattgatat tcctaatctt cccatctgtg tcatctcctt atatcctata tgtgtttaaa
    13381 tttatttcga attacacgaa acttttttaa aaatttgatg aaaaaaagtt tcatatatat
    13441 ttataaaaaa agaaaagttt accttttctt tttttataaa caatcaacaa aatatcttcg
    13501 ttacttattt cataactgtt atactttgaa atttatacta atctaatata gtttttaatt
    13561 tccaatatag tttctaatta ataagcttct tgctcttcaa ctttttcttc atgaagcaac
    13621 ctcttatcgt acatcttgac aaatggatag taaattatta ttgatatagc tatacataat
    13681 aagttaagaa ctgaagctct ccaatctcca ccagtggcta aatatgcccc tactggtcct
    13741 ggtaatgtcc aaggagcagt aactactact ctggatacta aattagcact catagcaaac
    13801 catgaaactg ttgccattac tattggtgct acaacaaatg gtattattaa tattgggttt
    13861 aatactattg gcgctccaaa tattattggt tcatttatat tgaatattgc tggtattaca
    13921 gttgcttttc ctaaagactt tccataagct gattttgctc taaatgcaag aagtaaagct
    13981 aagcctattg tagctccaga acctccaatc catataaacc attgaaaaaa gggttcagca
    14041 gcaatacctg gaactgcttg acccgcagca tatgaagctg tattagcatc taataattgt
    14101 atccataaag gtcttgccaa tgaacctatt attgatacac catgtattcc aaatgaccaa
    14161 aaaaacgtta ttaaaaatat tagtataatt actgatggta atgtgtcagt ggctgaaact
    14221 aatggagtta ctaatttagc tatgaagcca tgccaatcaa accctaggaa ataagtaaca
    14281 atagccatta aaattattat taatgcggct ggtgtcagag cttcaaaaga ccttgtgact
    14341 gatgctggaa ctgcttctgg catggttatc ttgaatttag atttgtcagt aaatctataa
    14401 atctcaacac ctattataga tgttacaata gcaacaaaca ttgaacctcc accaagatta
    14461 gccattggca tttgccatcc ttgaggaatt gaattatacc aagctaaaag ttctggactc
    14521 ttttcaacta tctttaataa atcaggggta agaccctcta ttgcagtagg aactattgtc
    14581 aaaaggaatg tagctgtagc taataaacct cctgtcaatc catctaactt atatgacttt
    14641 gccaaactat aacctatgcc aaatgtagaa tatactgata taataaaaaa tgtcattcta
    14701 tatggtagta atattgtaac tgcattttcc tttagatact gagttacccc ccatgaatct
    14761 ggtaatggag gaaatgctaa tatcaagaaa aatgacccaa ctattataag tggtaatgaa
    14821 gctacgattc catctcttac agctcttaag tgacgttgtt ctgccaatct ggccatagaa
    14881 gttgataatt tagtgtctaa aaattctgta aatttatcta gcatcttttc tctccttaat
    14941 taatatttat ttttattatc attaaaattt ttataaaatt aactttcttc taatctaaca
    15001 acactgcaac tactatttac tcaacagctc ttgaacttgt tttaataact ttggtcctcc
    15061 taatggacta taagcttgtg cttgtattaa tgcacatggt acactaacct catcagcaaa
    15121 agcttttaaa tagtcaaatc tatgtctaac ttgtggagct accatagcaa tatcccatcc
    15181 atttttaact tcatcctcaa actcttgagt accaacagcc aaaacatcta tatctattcc
    15241 attttttgct ccttcttttt gtaatgcatt aactgctata gcacttgaca tccctgatga
    15301 acaaacaaat aatactctca tattgattcc ccctgttttt ttatttcttt tcaatcatta
    15361 tagcatgtat ttttgattac aggaatacgt ttgtatatat ttttttcata ttttacattt
    15421 taaattgtaa ttttatttca tacatttata tcttgcttta attgctttat ttatctaatc
    15481 attcttttgt ctaaaattac acactactta aaatactcat atcttttctt aaaaaagaaa
    15541 aaagactatc ttattattaa cataaaatag tctcaatact tttttaaata tgtattcctt
    15601 tatatatcca gaagtaacct attattgcaa atgataaagc aaataaaata tacagtctaa
    15661 aaaatcccaa agaaaaacct ctcttagttt caacaaagta tcttgtatat gcaactgcaa
    15721 aagatgtaat taatgaattt cctataacaa ctccaaatct attatctatt ccaaatatag
    15781 ataataacaa aggaaaaact acagtactta ctagagatga aactattaat attaatccac
    15841 ttttaaaact tatagttgga atattataat ctgttctttg atttttctcc atttgtttct
    15901 tagtattttt attacttttt gtactttttg catttttata attattattt ttctttcttt
    15961 tctttttttt attattagac atgtcattta cctccaaaag gtttaggtgt tatattccct
    16021 aaaataactt tatttttagc ccctgttgca gatattacat tagaaaaaga attatttaat
    16081 gtttcattgc ccaagattac aaatgccaaa gcctcctttg catcagaaga atacccatat
    16141 tcatcttgag ttaatacttc aacctctaat aataactctt ttatatatcc tattaaagtt
    16201 agattatgag ctcctccacc tccaattaat aaagtatcta cattaacctt tggaagtatg
    16261 aagtttttat aattataata tatagctttt gccgtaaaca tagttactgt tgctatcaaa
    16321 tcatatttat ctacatgttt atatttgtta agcatgttat ccaaataaac ttgtccaaat
    16381 acctctcttc cagtgctttt aggtggcgct tgactaagat acttatgact catcaaatct
    16441 tttaacattt cttcattaat tttacctttt gatgcaaagt atccattttt atcatacttt
    16501 ctattaaata atctttgaca tactccatct attatcatat ttcctggtcc tgtatcaaat
    16561 gcaaatacat catctatgtt acatgattta ggtattatag taatatttcc tattccacca
    16621 atattttgaa gtgctaaatt tttattgtta tcactatata ataaaaattc actatatggt
    16681 actaatggag caccttctcc acctgctgct atatccatta ctctaaaatt agatattacc
    16741 tttgtatttg tttcatatgc tataactgct ggttcaccta tttgaagcgt tgaagataca
    16801 aaattattat aacttcttgg tatatgaaag attgtttgac catgagatgc gataaaatcc
    16861 aaatttgcta tatgaaagtt tgctttatga cacactgatt ttacagcttt actaaataaa
    16921 tatccaagct taaaatttaa gctacagatt aaatcaacac tcgattcctc ttctatacag
    16981 cactttctta tttcgtcttt tatatcttta ggaatttcta gagttataaa ttctatttgc
    17041 ttaactttag tatttctacc attcccacta atttcagcta gtactgcatc aactccatct
    17101 aaggaagttc ctgacattaa acctacacta tacatagtta tcatcctttt aagtttatag
    17161 ttattcctcc ccaaatcaag gtattaagtt taataatttt agaattaatc ttatttcatc
    17221 tttaattacg ataatttact cttatgaaat taattgagtt aatcttatac acgtttttta
    17281 ccttagctaa atcttacatt aatttatttt cagtgtcaat gtaataccat gtaatttttt
    17341 ttcacaaaca aaacatattc tctctccaaa aaccatatta aaatagttac tacaaataaa
    17401 aaacatacca ggtacctatc tgatatgttt ttcatatata ataattatta ttttataata
    17461 tagatagagc atcatttaag gcactaatta aatcttcact attttcaaga actaaattta
    17521 ttcttattgt atatgtcgat ttgtatatga tgatagattt tatagtctaa taacctaact
    17581 atctaggctt aaataatccg atatatcata aaaatagata ttaaaaattg tatatgaacc
    17641 attttccgaa catacctcaa tctcatgccc taaactatct atcattttct ttacaaaata
    17701 catccccatt ccagtagact tatacaattg atttcttcca tttttccccg taaatccctt
    17761 gtcaaaaacc ctagatatat cttcctcatt tatacctata ccaaaatctt ttatagataa
    17821 taccactcca ttttctaact tttttgaatt aaattcaatc ttaccaactt cctttgaata
    17881 ctttatagca ttattaataa tttggtctaa aacatatgac atgcatttag aatctgtgta
    17941 aacatcattt tctaattcat tcaaactaac ttctacatta ttttttataa gcaaaaatga
    18001 attatttttt atagacattt ttatcaattt ttctaaatta aatttattta taaatacatc
    18061 ttcaaacata gtgttgcttc tactactata caaaatagag tttactaaaa aatttatctt
    18121 tgcaacctga ttcttaatat ccaaactatc ttctatgcta cttaacctat ctgtaattat
    18181 acttaaagaa gatattggaa tttttatttc atgaacccat ttagctatgt actcatccaa
    18241 ttcttttaat gattgtttat aagtctctat gtcactatta ttttttattt ttaagttttc
    18301 tataatatct tttattagat tttcttcaaa agattgtcca tcaactaaat aactgtctat
    18361 ttcaccacta ttttctatac aattatataa atttgtgtaa ctatttctaa aatttatata
    18421 atctataaca aaaaatacca ttattataaa cagtactaaa aaatctaaat atattaactc
    18481 tgaatattta tttttaaaaa tatctatagc aaataagtag atatttatta tactaactac
    18541 aactaaaggt agagcaatat acttagacct acctttcaaa tattttacta gcattgtatt
    18601 atatatccta cccccttctt agtttttata aaatcatcaa aacctagttc tttaacttta
    18661 cttctcaatc tattcatatt tacagtaagt gcattgtctg tcacaaactc atcattatcc
    18721 catagagtca tcataagact ttcccttgat acaaccctat tcttattttt taataataat
    18781 gttaaaattt ttatttcgtt tttagtcaac tctatacttt tatccttata cttatgtttt
    18841 ataatccctt tccccacatc aaacatcaaa tcttcacaat acaaaatact attagaatca
    18901 ctataattat agactcttct tattatacca tttattttgg taaccaatat ttctatagaa
    18961 aatggtttgg taatgtaatc atctgctcca ttatttatac ccattattaa atccatatca
    19021 gaatctcttg atgataaaaa tattaatggt acatttgaaa tagctcttat tttttcgcac
    19081 cagtaaaatc cattatataa tggtaaattt acatctaaaa gtactacatc tggtttttta
    19141 tctataaatt catctaatac tacctcaaaa tcatcaatta attctacttt aaatccccat
    19201 ttttcaagtg ctaatgcaat ctcttttgat aaatcaatat cgtcctctac taataaaatt
    19261 ctatacattt gtatattctc cattatccta atatttcact atgctatgaa ttattaatat
    19321 cataacatat tttatatgaa tttattaccc aaattattta gttaatcaac aaggagactc
    19381 ttattacaag aatctccttt ctctttatta atatatcaac taatttttat acactacact
    19441 cttaaactta ttaacagata ctgctccata tattatgaat attatcaaac atatcactaa
    19501 acttagtata tatataccaa ataaatcggt catcaataaa tctcctgcta atctcaatgc
    19561 aaaataacta gatatagttg cacttaacat tggcaaagta taaaacatag ctacttcttt
    19621 aagtatagct ctatttatat ctttttctgt agtacctatt tttaacaaaa tcttatattt
    19681 ctctttatct tcatatgcat cactatatat tttcatatat attatacttc cagctacaat
    19741 tgcaaagact aagaataaaa acacaagcac tacatatgca aacttcatcc attgactctc
    19801 accttgagct ttatatccat tttgaatata cccatttttt aaacttaaat tcttttcaat
    19861 attgttgaac attacttgac tattttcttc ttgaaatacc tttgcaccat aaaaatacac
    19921 ttgttgaccc ttatctctta gtttaaaata tgtatcatca tttaccacta taatactttg
    19981 attaagtcct gtccctagta ctggaacttt tacttctccc cttgaaatat tatataactg
    20041 accatcaagt tttatcttgg cttcttttgt agctattgat gctatcgttt gagggctttt
    20101 taactctatt acattatttc cactaactaa tctttcacca tactctttta attctttatc
    20161 attgccattc actttaagag tattacaaaa atcactatat ttcattatag tatctgttgt
    20221 atcataagct tcttttatat ctgttttctt taaaattgtt agttctggat ttactgagta
    20281 ctttatctta ttagtatctt ttattatatt ctctatttgt tttttattca cttcatcttt
    20341 atccattgaa actatgctaa tagtgtacac atttctttgt tcttgggcat tcttatgtat
    20401 acgcttcatc gcaactgaag caccaagagt tgatattgtt gtagttataa ttatagctat
    20461 tatagcataa gttttatagt ttttatttaa tcggtagttt atattgttta ttgcaattat
    20521 attatttcca ttaaataata tttttttatt tttgattata atatcaaata taacaggcat
    20581 aactgatttg aataatccat aagtacctac tattattata cctataacag gtagtacact
    20641 agttatatct ccagttctta tattggtaga aagatagtag ccatatccta ttactataat
    20701 tgatactata gctaatatat atatacctat tcctaccttt ggtatttttt cttgtttttt
    20761 agatatattg attagattta ttacactact tctacatatt gttataaaac cttttacagc
    20821 cattattata aatatagaaa taaagattaa agtagcatat agtatagctt ctatactaag
    20881 tccattagat acctttatat taaatccaga taactttatt atcactactt gaaaaaatct
    20941 agatgttatt atccctataa ttattcctgt tatacaagaa cttattccta taagcatatt
    21001 ttctacaaaa tatatttttc ctatagtata taaatctaat cccataaaag acaatattcc
    21061 aatttcttta gacctattct taaaaaatat atttgttgca taccatataa agaaaaataa
    21121 aaatactgat agtatcatta ttacagctac taacactgat agtgtaaatt ttttattttc
    21181 atcttgtaac acatttatag catcaccata tcttaataat tcaaaattag ttagcacaac
    21241 tactgaaaaa accatagata taaaaaatgc tagataagtt cttatgttac tcttaaaatt
    21301 attataagca attccaagta tactcactta catctcacct cccatagagg ctagcatatc
    21361 cataattttt ccataaaatt cttttctact atttcctttg tttaatttac actttatatt
    21421 tccatcattt atcatatata cttcatttga ataacttgct gttagagggt catgtgtaat
    21481 cattataata gtagcgttat tttctctgtt tattttttct aatgattcta aaagttcata
    21541 tgctgattta gagtctaaag caccagttgg ctcatcagca aatatgactg ttggatttgt
    21601 aattaatgac ctagctgctg cgcctctttg tttttgtcct cctgataact gatatggata
    21661 tttatctaaa tgattttcta atccaaattt tttagctata gaaaatacct tagcttctat
    21721 ctccttactt ttcttttttc ctaatgctag aggaagtgct atattgtcca ttagtttcat
    21781 attgtctaat agattatagt cttgaaatat aaaccctatt ttttctcttc ttaattttga
    21841 tagttcatta ttttttactt ttgatatatt aattccatct agtattattt ctcctgaagt
    21901 ttgtttgtca agtgtagaca ttaaatttag caatgttgtc tttcctgcac cagatggacc
    21961 cattattgat ataaaatcac cttcattgac tgtaagagat atatttttta acacatttgt
    22021 tttaaatcct tttattccat aatcttttga tatatttttt atttttaata tttctttcat
    22081 aataatagcc tccagttgct aattttttaa tatatattta ttttaaaggt tttatataaa
    22141 taaatcctta agtaaatatt acattttaac tgttagcatt acacttttgt aacatatgga
    22201 agactattat aattatagta gaaatatctt aaaataaaag catgatttac ttctttgtat
    22261 aaacaaagaa aagaagctcc taagaagcct ctaatctata caattattct tctctataaa
    22321 aaaccaaaat acacattgat tgtggcaaat acagatacta taaacaagtg atattactac
    22381 tatatattaa aacaattatt cctgaagata attcaataag actatcaagc aataagctaa
    22441 gcatccaaaa agacttaata ccattaatgt ataattatac ccaatattaa tgctcaaaaa
    22501 accagcaaca gttggaataa tcagagatga acctcccata aatatactta aagctattaa
    22561 ttggctacta cttctaagtt ttttaggaga aacttcaaat attaatcttt ttgaagtaat
    22621 taaaattaaa ggagtagaaa acacttgaaa aacacacagt ataataatga tatttgaatc
    22681 atttgttaaa gcaaataata gaaactgaac tgttatcata atagcactta attttaataa
    22741 gtttaaactg ctatattttt ttaataaata agaaccagcc agatatgttg gtatctctaa
    22801 caatgactgt aaagaccact ttaaagatat ctgagaattt gtagcattta aagctatcat
    22861 tttatctatt acagtacagt tatttgctac caccattgag tataataaga ataaaataca
    22921 tactagtaag atatattttt tatcttttaa taattcaata atatctttat tagttacatt
    22981 tattttctta ttaatctttt caatatcagg taataatagt atatttataa taagtaatac
    23041 tacaattaaa ccaatcgcta cagataatcc aaaatatgag aatctaagaa tcaagtaaga
    23101 tgctaccata cttccaatag cccatccaat cgacccaaaa gtcttaataa atgacaaata
    23161 attattaata ttatctccac aacctattat ccatgtatca tataaactac agcaagtatt
    23221 taataatcct cctgataaag caacaagtaa taagtatatt ataaaagttg cagattcagt
    23281 agaaaacata ataactgatg caattccata aactgataaa ctaattaaaa caattttttt
    23341 cattgtttga tacttatcag ctaatactcc aaataataat tgaaacaata tattggttat
    23401 tgcatagctc gataatataa ttcctctttc aaacgctgag taacctaatt ttgataagaa
    23461 aggtgtgaat tttgttgaag caaaggcaaa aataatatat gagaaaaaat agaatatgat
    23521 aaatttaaat ttaatcgctt tattaatcat aatcaatcaa aattgataac tttaatacca
    23581 ctatttcctt cctgatttaa gtttgaaaga tgatatttta ccgtattagg attctctaca
    23641 ataactaaag gaatatataa agtattttca agtaacttat tatcaatttc tactaacttt
    23701 tcccccatat taacttcttg accttgttta acttctaatt taaagttttc tttttttgtt
    23761 gttgcactat ccaatccaat atgaataaga atttgaacat cattttgcaa tttaattcct
    23821 atagcatggt tagtttgagc aataaaactt attactcctt tagtcggtga tttaagaata
    23881 ttgtcctttg ctatcatagc aaatccatct cccattacct tagttgaaaa tactttatca
    23941 ggaatttctc caagattaat tatttttcca tcaatgtatg aattaattgt aattgcttct
    24001 ttttttcttt taaagaacat tatagacact cctctacata attaacttta ttctaattat
    24061 cattacaaat aacgatatta agcatactgc aattgaggaa aaaagagcct tatagctctt
    24121 tccccattgt agttctttaa tactgcttat gatttgttta attccaacaa atttataaat
    24181 ataggtaaac atgataacaa tagttattgt gtaaatttgg aatatctgcc ctaataagac
    24241 taaatagaaa gcaatcatgt tttcttttat ctctttattc ttttttatat tgtaaataac
    24301 atatgcactg tatactgcac taaagttaga gattaaattt aaacttgcat taacatcatt
    24361 gtttaaaagt tgtgaaaatg aaatatttgt aaataatgat gtcaattcta aatacactat
    24421 atataaaaca ggtaatatta gaaaacaaac cataaccact gaaagaaata tattttcatc
    24481 ttttaatact gctgtgatat tttttatttt atttgttatc atgtttttgt tctccttatt
    24541 taaaagttgg ccagaaatcc ttattagcca caatcatttc atctaagatt tcttttgcta
    24601 cttttgcact tggaacagtt ttactcatag taaacgactg ccataatttt tgataacttt
    24661 tttctatcca tgcttctaca gctaattttt cagaagcaac ttgttgttcc attaaacctt
    24721 tttggaaagt tggaatttta cctatagaca taggttcaac catatctttt ccaacaaggc
    24781 aaggaatttc aaccattgca tcatctgcaa aattttcaat agctccatta ttaggaacaa
    24841 tcagtaaaaa tctttcctga gtattaaatg ctaatgcaca agctaattca acaataaatt
    24901 gagaatgttc acttgcatca aaccatgtat ctcttgctgt gccatttttt ataattcttt
    24961 cacattcttc gaatgtatcc ttttctcttc tatccataat ttcatttgct cttgtataat
    25021 ttggattagc atgttcaaca gtttcatcag ccattaaata atattttaaa taagtattag
    25081 gtaatgtagt cggttctatt tccaataaat cctttgctgc tctcatagtt tctaaccaac
    25141 tagattcttt gtgttgacct tgaggtgtaa attcctcata tcctttttta gcacaatatt
    25201 cctgtaattt aggcattaaa tcatttcctt ctttgtcctt aatacttgtc caccacccga
    25261 aatgattcaa tccataatat ctaacatcaa agtctttacg agaatttaaa cctaaaactc
    25321 tagcaaatat ttcctctaaa catactggca tatcacaaat attaataatt cttgaatttg
    25381 gtcttaatac acgacatgct tctgcaacta tagctgctgg atttgaataa ttaagcatcc
    25441 aagcatttgg agaatatttt tccatataat caatcatttc gattattgga cctattgttc
    25501 ttaatccata ggcaattcca cctgccccac aagtttcttg accaacaacc ccatatttta
    25561 gtggaatttt ttcatcttgt tcacgtaaag catataaacc aacacgaatt tgtgccatta
    25621 caaaatcaat atcagtaaat gcttcttctg gatttgttgt ataactaaat ttaatttctg
    25681 gatttttctc tctaacaatt attgcacatg cttcagcaac ttttctttgt ctctcatcat
    25741 tattatcata taatttaatt gattcaatag gaaatttagc aacactttca attaacattg
    25801 ttacaattcc agcagtataa gtactacccc caccagcaat tagtatcctc tgtctttttc
    25861 tttccatctt tccttctcct ttataataaa ttttcaaatt cttctcttac acttggtact
    25921 gaaagcccaa taataatctg aatagctttt ccattatgca ctaaaccatg tgcacctact
    25981 gccttaaaat cttcttcttt agaaataatt gagtcatctt tcaaggttaa tctcaacctc
    26041 gtagcacagt ttgtaacatc tacaacattt tctgctccac caactaattt tatgtattca
    26101 gatgcttgtt gagaggcttt actcaattta tttccttttt catctttagt ttctaagtat
    26161 tcatttttag tatatagttt tgtttcttca ctatcttcct ctctaccagg agttttcata
    26221 tcaaacttct taattaagaa agtaaataca aagaaccaga taaatgaaaa tataatccct
    26281 acaacaactt gaacaacata taccttccag tgatacattc caagaggaag ccaatttaat
    26341 acaacccagt taataattcc tccaccaaaa tcaccaacaa ctcctagggc aaacgaaatc
    26401 gtttgcaagc atgcatctaa aaatgcatgt actaggaata aaagtggtgc tacaaataaa
    26461 aatgtaaatt ctaacggctc agtaattcca gttaatactg cagtaagagt agcaggaatc
    26521 attaaaccta atactttttt ctttttttct ggctttgcag ttacatagaa agcaccaaat
    26581 acacctaatg aaccaaacac cttcgataat ccggataatg aaaatccgat tggatacatt
    26641 tcctttagag tcttagctga agtttgaaaa tcctgaatat gagtagccca atatactgat
    26701 gtaccacctg gaacaacaac actatcataa caaattggtg catatacaaa atgatgtaat
    26761 ccagttggta ttaaaatctt ttgtaagaat gcataacacc aaactcctat atttccacta
    26821 tttataaaaa acgtttgcaa atgtctaata acattttgaa tatgaggcca aataaaacaa
    26881 gttaataatg caactggtat cataacaaag aaacaaattg caactacaag tgatgagcct
    26941 ctaaataatc caataaaatc tggcagttct ttatcataaa atctattatg aatataaatg
    27001 acaatacctg atattaacaa agcaccaacc ataccagtat ctaatgtttt aataccagca
    27061 atgcttacaa gtccacttcc agcacttatt tcagctgcga aatcaactcc aaagcttttt
    27121 ccccaaaaac ttaacataga acctacaaaa taattaaaag tcaaatacgt tgctaaagcc
    27181 tccatacaag ctcttgcttg ttgctttttt gcaagtgcta ttggtaaaga aatagcaaat
    27241 aataatggca attgattaaa taccatccaa gctccactag atattacacc ccaaaattgg
    27301 taccaaatat tttctggtgt agcaagtgaa cccataattg actgattttg aaatacaatt
    27361 gagaatccaa ccattatccc agcaaaagca aataatagtg ttggtgtaaa cattgcccct
    27421 ccaaaacgct gtattttctt catcatataa attactcccc tcctcatatt tttagtttat
    27481 ctttggcctt agatatctat tattttaaca ggttaataaa tatatacaat ctttagggta
    27541 cattcggagc ttattcacag tcaaataagt ttttgcacat ttttatgttc aaattctcat
    27601 aaaaaaaaag aatgactaca atttgcaatc aatcccttct gtaatcattc tatgcctttt
    27661 ataaatacta tatttaataa ataataactc aatcaatata aaatataaca ttgtcaattt
    27721 ataactaggg tgcatttgta aaaatgagat attagtcgct gaaatataaa ttgattcatc
    27781 acttaaatca gtcaatgtat tatttttaaa ctctgtaatt gaaattattt tagttcctat
    27841 taattttaat cttctagcaa tattaagtgt attctcattc tcaccactta gggatataat
    27901 aatcataaca tcatttttac tgacaatatt gtaaaaagaa tcatcaaatg ttcttccctc
    27961 aaaatcatat attatttctt gacatgataa gaacattctc tttatctgtt ttgcaaccac
    28021 attttgaata tcacctgaac cataagcgta tattgttctt gattcataaa gaagtttaca
    28081 caatgcatca taatctttat ttttttgatc ttcaacatac ttaattattg aattacatgc
    28141 aatatcaaat gactgatttt ctatgacatg aaccttttct gattcccagc ttaataatac
    28201 tttaaactca ctgaaacctt ttaaatctaa ttttttaaca aatcttgtaa tagttgcacg
    28261 agacacatta catttcatag caagttcatt tattgacatc ttactacaat gttttttatt
    28321 tgcagttata tatttccata ttaataaatc tgtatcattc aatttattat aatttaaaaa
    28381 aatcatttct tctaatctca taaactatta ccccctttaa ttaaaaatcg tcataaatat
    28441 tataccaata ttcaacatta aattacagcg tattcttata tttactattt agcccataaa
    28501 attgactata aaaaatactg ctataattga tgtttaaaaa aatgtagttt taattttatt
    28561 cttttatcta ataattaata ttttcaagtt ctagtgcttt tcttatacaa ttatcatctt
    28621 taaaatcagc agtcctttta caatctttta ctttaaattc tggaatagtt ttaaattcct
    28681 catcacatat tccattctta tttaaataca tacaacttgc cattctaact attagaccac
    28741 tattttttaa attaaacaat acagggtcta tacaccctcc atctccgcca gtagtttcac
    28801 caactaaagt cgcaaattta ttttctttac aaaacattgc aaatgactct gatgatgaat
    28861 atatttttct atcaacaagt aagtatatat tacccttaaa ttttgaatca tctgtagatt
    28921 ttatagtata ggaagtatct tcaaaatcat taaaatcttt tataatttct ttaggtgcat
    28981 tttcctttac acttgctggt aaattttcta caggatttaa ttttatattt cttgcatttg
    29041 tatatttttt tactatttca ttattatttc tataaattct ataaccattt attttgacat
    29101 cattttttat gagtttagat acgattccct gccaatacct atcacttcca cctaaattac
    29161 ctcttatatc aataattaaa gctttatgtt tttctaaagt gttaatataa tctccaatta
    29221 tttttaaatc attatttata gagccattct ttgatgacat tgatggtaaa tacatatatc
    29281 caatctgacc cttaataaca tcctttaaaa ttaattcttt ttttacaaaa atatcatctg
    29341 gcatttttat tttaagattc atagagtcat atctatccac aactttttta tcattaagaa
    29401 aatcatacca atcattatta gagtatgatt tcttaaaaag ttcatatctt ttcttattat
    29461 ctattacttc tgtgtgttta ttatttaaat cagataatat agatgacagt tcttctataa
    29521 attcttcatc attttcagtg ttttttattc gttttgtata ttcatcctta tttgctaacc
    29581 aatcaatatt attaagcctc ttatttacac ctagatatgg atatcctgtc tttacaacat
    29641 tatacacata attaaagtca tccacctttt cctcttcaga caactgattc ttttgagaat
    29701 aagtagaatt acctaataat attataaatg ctaaaataat tactaaaaat aatactttct
    29761 ttttcatgta attctcatcc actttcagat tttatatttt aatacattgt atcattattt
    29821 tattatcacc taaacagtta aaagaaattc ttgaagatat attccactat tattctcttt
    29881 aaaaattttt atttgtattt tcaaaattat ttcatgaaag ttataaaata acaattatat
    29941 tcaaatatct attttactgc tatatcctga aagtaaattc ttatcagtga tatactaaaa
    30001 aagatatgct aaaaaattta tccattataa tgacttaaat ttagatactt tactgatttt
    30061 tatttattag ttgagaaaga tattgataat taaaaatatt gataactata gaaatgatta
    30121 ttttttatag aaattttaag gatataaact aattatactt aagtctatat ccttaattta
    30181 tcatgattat gagaattttt acaaatactt atctttgtcc gttttagaat aaaaacaaga
    30241 acatatcctg ttattttatt caaacatcca agtttaatta ctacacaatt acttattaga
    30301 aattgtatct acttcatata tatatctgtt aagtatagct tctagcattt cttgtcttcc
    30361 agacttattc tttataactg gcatttgcag tgcataagat tctaactctt taaatccaac
    30421 cttaccttct actatatcct tacctatacc ttcactaaaa cttgcatatc tttctttagt
    30481 aaagttttca aatacctcat cttctaataa tttatgagct attaataatc cctttgcaaa
    30541 tgtatccatt cctgcaatat aagctaggaa taagtcttct acctcaaaag atgctcttct
    30601 tactttagag tcaaaattaa accctcctgg tgctattcca ccttgcttta acacttcata
    30661 catagcaagt gttgcatcat atatatttgt tggaaattgg tctgtatccc aacctaataa
    30721 taggtctcct tgatttgcat ctatactacc taaaacattg tttattcttg ctatatttaa
    30781 ttcatgttgg aaagtatgtc ctgcaagtgt tgcatggttt gcttctatat tcattttgaa
    30841 gtatttatcc agattatact ttcttaaaaa tcctaaaaca gtagcagtat caaaatcgta
    30901 ttgatgttta gtaggctctt ttggcttagg ctctattaag aattgtccag tgaatcctat
    30961 ttccttagca tagtctacag ccatttgtaa gaatcttgca aagttatcca tttcaagttc
    31021 tgtattagtg ttaagtaaag tttcataacc ttctcttcca ccccagaata caaaattttc
    31081 tcctcctaag tacttagtta tttccatagc ttttttaacc tgagctgctg catatgcata
    31141 tacatctgca ttacatgttg tagatgcacc atgaacaaat cttggatttc caaacatatt
    31201 ggcagttccc cataataact ttatacctgt cttttccata ttaactttta tatactcaac
    31261 tatttcatct aatatcttat ttgtctcttc taaatctctt ccttctggtg ctatatctct
    31321 gtcatgaaaa cagaaatact caattcccat cttagacata aattcaaatc ctgcatcaac
    31381 tttaatcttt gctatctcaa ttgggtctgt tatattattc caaggtctct ctactgtgcc
    31441 tactccaaat gggtcattac cctctccaca taaagtatgc caatagctca ttgcaaatct
    31501 taagtgttct ttcatagtct tattacctac cacttgttca ggattgtagt atctaaatgc
    31561 taattcattg tcagatttta ctccttcaaa ttttatctgt cctattcctt taaatatttc
    31621 actcatttca tgtcctccta atattttaca catataatat atgtagtatg ttttcttaat
    31681 ttaaaactat tttctatctt tatttttctt tttaagctaa tttaattatt tatttttgca
    31741 ttaactactt catctaataa cttaaagtca tctttcaaag atttgtatat tcttttatac
    31801 aatctatgat atatattgta tgtatctaca ttttcactta ttggttctaa tttagttgaa
    31861 gtttttatta tagcatcaca agctttttgt atattttcat atattccagc tcctactaat
    31921 gcaagaattg caactccaag tgctggtcct tcacttgaat ttatagtata tacatcttga
    31981 ttaaacatat ctgcttgcat ctgtctccat actttacttt ttccacctcc acctgaggct
    32041 cttacttcat taacgtctat attaagattc tctattatat ccatacagtc tttaagacta
    32101 tatgaaacac cttccattat tgaccttgca atttcttttt tagaatggat tggagataat
    32161 ccaaagaaca cacctcttgc ataagggtca agatgaggag ttctttctcc catcatatat
    32221 ggtaagtaaa gcaatccatt acatcctgtt ggtactttac ttacttgatt atttataatc
    32281 tcatatacat cttcacctaa agaatttgaa acttccactt cactttgaca gaaattatct
    32341 ttaaaccatt ttaatgacaa gccagctcct tgagtaactc ccataacatg ccatgtattt
    32401 ggtattgcat gacagaaagt atgaactcta ccttctttat caatttttgg ctcttttgta
    32461 taagcaaata ctacacctga tgtacctata gtagatgaaa ctactccatc tttaactatt
    32521 ccatttccta tagctcctgc tgcttggtct ccagctcctc ctaccactat tgttccttct
    32581 ttaagccctg tcaaacttga tacatctcta gtcacataac ctgtaatctc ttgtgattca
    32641 taaactttac ctaaaagatt tttatctata tttaactttt ctagtacttc atcgctccaa
    32701 tctctttttc ttatatcgag caactgcata ccacttgcat ctgatacctc tgtagcatat
    32761 tcacctgtca atttgtatct tatataatct tttggaagaa gtattttatt agtattttta
    32821 tatatatctg gttcattgtt tctaacccat aatatctttg atgctgtaaa tcctgtaagt
    32881 gctggattag cagttatttc aatcagtctt tcttcaccta ctaaatcagt tatctcctca
    32941 cactctttta ctgttcgttg gtcacaccat attatagagt ttctcaatgt tttaccttca
    33001 ttgtccagca taactagacc atgcatctgc cctgataatc caattccttt tatacattca
    33061 ctgcttatat ttgaactttg aactacttct cttatagatt cgactacagc tttccaccaa
    33121 tcatttgcat cctgctctgc ccaacctgat ttctcttgta taagaggata ttcatatgta
    33181 caacttttta tagtatttcc tagtttatca aataaaactg ttttcgtacc tgatgtacca
    33241 atatccacac ctaatacata ctccaacttc atccctcctt gaatgccact tcataactat
    33301 cgttttccta tcctaatttt tttatatttt aggtatattt tacttgcttt atttttgtta
    33361 gtatattaaa ctaacttatg aactaataat aaaatattta attatctttg tcaatgcaaa
    33421 ataacctttt atttttgtgt aaaaagtatt acaatattat tttaaggagg aatatcaaat
    33481 tggttactga taaatacact attcgagaaa tgaatgaaag attggtactt gaacaaatta
    33541 taaaaaatgg tcctatttct agggcaagta tagcttctac tataggattg aataaagcaa
    33601 ctatatccgc tattaccaaa aaacttattg atgaatctct agttcatgaa ataggaattg
    33661 gaaatagtac tcatagtggc ggaagaaaac ccatattatt agtatttaat aaatgtgcag
    33721 ggatttcttt aagtatggac attggatacg actatatatt ttcttctcta tcttacttag
    33781 atggaactat tataaattct aagaaattaa cagatataca agtaagtaaa gacaatgtta
    33841 tacaattgat agatgaaatt ataaatagtt ataacatatc caaaatagac actccttata
    33901 aggtaattgg tcttactttg gctatacatg ggattacttg tgaaaataaa gtattgttta
    33961 ctccatatta caatcttaat gagattgact tatatagcat ccttagcaaa aagtatgact
    34021 ttcctattca tatagaaaat gaagcaaact taacagcttt agctgagaat actttttcaa
    34081 ctgtacataa ctcactactt agtctcagta ttcacagtgg atttggttca ggcattataa
    34141 taaataataa attatatagt ggcagaaatg gtatgagtgg agaaattggt cacactatca
    34201 tcatgcctaa cggtaaacta tgtccttgtg gaaatcgtgg ctgtttagaa cagtattgtt
    34261 cagaaaaaaa ggtatttgaa cagctttctt ctttagaaaa tattcctaaa atagattctg
    34321 atatagtaaa gcaactatat tatgaagata accataatgc caaaaaagtt attcatgagt
    34381 tttgtagtta cttaacaata gctataaata atgctattac aacttatgct cctgaaataa
    34441 tatatttaaa tagccaaata attagtgata tccctgagat attacagatt acaaaagata
    34501 tgttagttag ctcttttaac aaaggaataa atatagaaat ttcatcatta gggtctgagg
    34561 catctctata tggtggctct gctgtaaata tcaagagctt tttgaatata caaaatttaa
    34621 ctttaattaa tgaaatataa gggttatgac tatatacagc cataaccctt taaattatac
    34681 attctaaaat tagatttatt atatagttta tgcaagatta gctatatttt ttaaaaattg
    34741 tatatcaatt aagtattaac ataagtattt cgttttaaat attaatataa tcttcctact
    34801 catcatcaga taataaattt gcattttgtt caaccataga aatattatct ttacctattt
    34861 tctctaattt tgctgccaat tcctttgtat ctaaaaaagc tgattcaata accataccta
    34921 aatttagccc tgaaataatt ttaattcgac tgtcattatt ggctactaat aaagcagcat
    34981 tgcatggagt tccacctagt aaatctgcca ttataattat ttctgaactt tccttgtaca
    35041 cttctaaagc tttttttaat ttttctattg ttccttctat tccatcatct tgtttcatat
    35101 ttacagtagg ataatctata gaatccccta ttatcatttt tgcagaattt aagacttctt
    35161 cagccatatt gccatgactc atcaaaataa tactattcaa tttaatacac ctctttaaat
    35221 ctataagatg tctacaagat aagttttctt atcatcaggc gtcattatag ttgtaatttc
    35281 aattccttca tctaaaagtc ttttaaatgc ttctttctct tcttcagtaa cactgatatt
    35341 aggtcttaga actgttgtat cttttctact tgacatattt cctacattta tattatgtat
    35401 tttaaatcct gcctctacaa atggaataag gtccacagga gacttaacaa ttaataatac
    35461 attttgtcct tcatactttc ctgcagtaat attttttata gcagtctctt ctgtaattat
    35521 agatgacgct atacctgcag gtgtagccat tcttaaaact tgtttttgaa cagaattgtt
    35581 agctactgca tcatttacta ccattaatct tgtaacaccc aatttattac tccacatagt
    35641 tgcaacttga ccatggatta aacggtcatc tatacgaata tttttaatac ctttcatttc
    35701 catatctaat atcatccttt ccttatttta aaatacctaa tgcatataaa attattgaaa
    35761 caaccattac tcctaaaatt aagtatatag gttttatatt ctttttaaga gcccaataaa
    35821 caatcacaac taaaattgca ggaactaacc caggcataat ttgatctaat atttcttgac
    35881 ctttcattgt aaaatcacct tgttgaaagt tcaaagcaac attagctttt acaactgaag
    35941 gtattaatgc acctacaacc attaaaccta aaatagatgt actctcagtt aaaatcttta
    36001 aacttttttc aattgaagat attagcttag tacctgatgt ataaccagca ttaaatagtg
    36061 gtatacttaa taatttcaat gctacactca ctacaatcca cagtaagatt ccaaatggac
    36121 ttccatctat cgccatatta gctgctatag ctccaaaaat tgtccacgga ataacgacaa
    36181 ataaactatc tcctaaacct gctactggtc ccatcaagcc tgttttaatt gaagcaacag
    36241 cctcttcagt ctcttcactt gataactcct ccattgctac attaataccc aaaatataag
    36301 gggcaaccca aggattagtg ttaaaaaatt gtaaatgatt taatacagca ctttgtaact
    36361 tttctggatt atctttgtat actactttta aaaaaggtag tactgcataa cagtatgcca
    36421 aggcctgcat cttctcataa tttgaagaaa cagaactagt aaaaaaccag cgccataaga
    36481 cacttttttt caccttttca tttgatttat ttaatgatac cttatcactc atcttcgtcc
    36541 atacctccta ctacagtata ttgttgttct tgattttcca aattcttttt gtaaattata
    36601 agtgcaattg ctccaccaat taaagctaca cctaataatg gtactttcat atatactgct
    36661 aaaacaaaac caattactaa gtaactaaaa tactccttag caggaagata tctaagtaat
    36721 aatcctatcc ctactgctgg aagtagtcct ccagctactg ttaaaccacc tgttaaccat
    36781 tcaggtgtat atttcaaaat ggtattaatt aaagaaggtc caaatattac agatagagca
    36841 actggaatac ctgttgtagc tgctgttaat agtactccta acatttgcat ataggttata
    36901 tttttataat ttcctttttt agctccatct tctgctttat gaactagcca tataccaata
    36961 gtatttctaa gaacatctaa ttgtaccatc aataaagcaa ctggaatacc tatagagatt
    37021 cctacagatg cttcttgctt agtcgtaata gttataaatg tggctactat acttgctgtt
    37081 tgataatcag gtattgatgc tccaccaaag ttactaatac ctaatgataa tagctgtaat
    37141 gtacctccaa tatataaccc tgtatttata tctcctaaga taagaccagt aataaaacct
    37201 gctgttactg gttgatatgt tccaaacatt gttgaatttt tttcatagtt tataaaaaat
    37261 ccatatagta cgattaataa taattgccat aattgtggct ccattatgat ttcacctctc
    37321 ccaaaatatt ttttagttct ttaaaattat aactggaatc ttgctttagg aaaataggaa
    37381 tttcttccag tgggcattca acttcataag ttttcccacc ttcataacta actccactaa
    37441 atatattttc ccatgtatgt ccttttggta aatatacttt tctacttcta tctttataat
    37501 tcattattgg agctactaaa atttcatctc caagcatata tgtattatcc acctcccaag
    37561 ttttatcatc ttcaggaaat tcataaaata aagttctcat aactggtgtt ccatcttcat
    37621 gcgcttcttt catcagtttt tttaaataag tttttaagct ctctctaatt tttatgaatt
    37681 ttgtaagaat tacttcaact tcttcaccat aagaccatat ttcattagga gctccagtta
    37741 ccattgagcc tccaccttta tttgataatg gtttactatg aggcaatcta tctccatgca
    37801 ttctcaaaat tggtgaaaaa gtagcatatt ggaaccatct taccataagt tctctaaatt
    37861 ctgggtcttt aggatttcct ccatggaaac ctccaatatc agtagtccac catggtatac
    37921 ctgccagtcc catatttaac cctgtattta cttgattatt aaaagcttca aaactagaat
    37981 caatgtcacc agaccatact aaagctccat acttttgagc tcctgcccaa gctcctctta
    38041 caagagttac aacagactct atgtcattat gtaaaccatc ataaatcatt tttaaataat
    38101 caataggata aatattacca caacttaaaa catttccttt tttatatcta tagttatcaa
    38161 aatcatacac agaatagcca ggttcagcta catctaacca ataatagtca atcccaagtt
    38221 gtttataatt tttatctatt ctatcccaaa catattctct tgcattttca tttgtcatat
    38281 ctacaaagac tgtatttcct tgaatttgca ttgtcattct aacaccacga ttaacattga
    38341 ctaaatagcc attttctaaa taatcattgt agttttctgc atcactttga actgtaggcc
    38401 atacagatac tattggttct actgaatact cttctttcaa ttttttaact aattctttag
    38461 gatttttcca ataatctaag tcaaatttat attcaccttg cttaggccaa tgaaaatagt
    38521 caattgcaat tgatgaaagc ttaattcctc ttttagaata ttccttcaca acatctaaaa
    38581 cttcttctga agttctatat cttagtttac tttgccatag tcctaaaagg ttttcaggca
    38641 tcataggaac agttccagta acttgagagt aatttttatt taactctttt gggctttctc
    38701 cacaagtaat ccaataatct ataaaatttg tagaaaacat cttccattct gtcatatttt
    38761 tagcaaaaga tacttttcca attcccggat tattccataa aagtccataa cctagactag
    38821 aaatataaaa aggaactgat atttgagaat ttctttgggc taactccaaa acagtattct
    38881 ttaaatctaa aaatttatgt tgatattgtc ccattccaaa aatcttttca gaaggctcag
    38941 attcaaatct agtagttact tcaaattctc cactatagct tggtcgatat tctcttgatt
    39001 ttaactttag agtagagtta aagtctttgg taatctcaat tgtccctaca tcttctccac
    39061 catcatcatg ttttacagct cttaatcgaa tatattcttt caataatatt tcatttttat
    39121 cattataaaa agtaattcta tctctatggt ctaagacagc ttttatcttt ccatttttaa
    39181 tgattgcact tccatcttca tttttattaa ttgtaatatc atctttattt aacttaggtt
    39241 tttcgttaag agcatagttt tcatcaacaa aattttggtc tacaaacgac ctaatacgta
    39301 aagagttttt tccccatgct tctattcgca atagttcatt gtcaaatctt ttttcaatat
    39361 agtcttcaga tatttttatc acggctacct cctaaatcaa tggtataata ttctatcttt
    39421 gtgtaactta agttaaataa tgtcgtttag tatcgttatt tataaattag gttttatata
    39481 taattcattt gtacattaaa ctaacttacc aataatatac tttatttgac tttgtttgtc
    39541 aatcgctttc cggattttag taaaattttc taatatattg ctggaaagtt gttcttaata
    39601 tcttttattt atacttttaa tatctgtgat gatacctata tacatctagt ttttttaaaa
    39661 cacatacagg aataacattt gcctattatg tagataatat cggacttgaa aatatgtata
    39721 gtgaccttat aaatacagat aataatatat tagatattgt tcaaaacaat ggattttata
    39781 attataaata atttatgaaa ttatttaaga aaatatacaa ttgtatacca agtcaaaaac
    39841 gacaacaaat aaataaaact aaaaaagatg ttgtctcaaa atatagataa atttattttt
    39901 cattgctaaa atgattaaaa tatatttgat ttaatatact tgatttaata taaaaaaaga
    39961 gtgtctcata aactaaaaag ttcactttta gacactcctt tatatatatt atctacttct
    40021 taattcattt attacctttc tacattttct ttcagctagt ggatacatct ttataagtac
    40081 taattactcc acttaaaaat ggttcctgta ctgtccatca gtcatatttt tctgccaaat
    40141 ataatggtgt ttcataatga gacaataaat atttatatct ctacttatct tctctaagct
    40201 cgtcaaatcc aactataggt atctctaaat tatattcttt aagtagcttt tctagctctt
    40261 ctataaaaat acctttccca tccaccattt gtatatcctt tattttatcc atcaattcat
    40321 tgcaaccact taactcacca aaccaacgtt tagaactaca tgtcttatta taaccacaac
    40381 ttggactgcc atctattgca atgatacttt ttatatcata atcatttttt aaatattcat
    40441 caaactgcct tacatgaggt attaacattt gcctacattg ttctctaaaa aacaaattgt
    40501 caaactgttc ttttacatgt ccccacctat ttattccata cataatcatt tctgggcatg
    40561 gtagttgaat tattccatac cctttattta ttaaatttat cgctatattt tgtgctccct
    40621 taaattctga caatccctcc actttagaat tacaatttaa tatacaatga catactacta
    40681 caatctctct atttcttttc ataataatct ccttagttat tcttaatttt aatgatacta
    40741 catattttga taattatatt atttatttgt tctatatttc caatattcta tatagaaata
    40801 tacaattagt aatcttttat aatctatact atgataaatg tatatatttt tttaggaggt
    40861 attataattg gatactaaaa aagtcacatt ttcttcaatg tgcatagtta ttaatattgt
    40921 cttaggtatg gttatatcta tgataaatat accattatta tttttagata cagttggtac
    40981 tgtacttggg gctgtcgtat taggtccttt ttggggtgct cttattggtg gatgtacaaa
    41041 cttagtttta ggtgttatat caggtcctac aaatatacct tttgcccttg taaatattgt
    41101 ccttggtctt attgttggat atatttctaa gaaaaaaggt tttggttata aagaagctat
    41161 tattacagga gtaattttat ctattgtttg tcctttaatt ggtactccta tttcagtttt
    41221 attgtttggt ggtttaagtg gaagtggtgc tgatttattg gttggttttt tagttcagtc
    41281 tggtcagaag atatttactg ctgcgttctt tccaaggatt cttagtaata tagtagacaa
    41341 acctttgtct tgtattatgg tggtatattt tataagtaaa atgcctaaag gttttataaa
    41401 acaatatagt aaaaatactt ctagttcata ttaataaatc atttattatg taaggtttat
    41461 tactctttaa aatgctatat actcattttt atataacatt tttattaata atttaattag
    41521 atagtatttg tattacttta attaaacgta acctcttgat ataaatttga gctataaatc
    41581 tatatcaaga ggtgctattt tatttttaat ataattaata ttctattacg caaaaaatgc
    41641 atatatttca ttattttatg gaaaatatta cttcatttaa ctctatatca aactcattaa
    41701 gtaaaaatct aattatattt aatttagcct ctgtatttaa atttgtttct aaatatatat
    41761 tttctgatat tttaatacct tttcttaatt tatatgcatc tctagactta atattatcta
    41821 taaaatctct tttataagtt ttgtctacaa tactgttaaa ccttacagaa tccaaatcat
    41881 ataaagtaag agcaacttgt tcataaaatt ctgtccaatt tttagcctta tatgactctc
    41941 ctaatatact aaatgatact atactttcat ttgtaaaatt aacatcatca tcctctaacg
    42001 taaatatatt ttcactgtta cttggaggtt catatgtaac acttggatat ttccaaattt
    42061 ctacagctct atctagtaat atcttagttc tattttttat ttcttcttca ttccatttat
    42121 ctatagatga aatatattta tttagataaa gcctactatc tttaaatcca tcttccattt
    42181 ctttcttttc ttcaaatgtt ttattactta gttttgaatt atatcctgtc aaagttaaat
    42241 ttccaattgt atgtaaatat ttatcatgta tctccttata gttatctcct agtgattcct
    42301 tccatttatt tgttaatgtc tgtggcatta tatgctctat atttagcata ttattattga
    42361 ttaaattttc taaatcaaca atttctttat tactataatt ctctaacctc tcaagtatat
    42421 ataacttatt ctttgactta gtattatata tatctttagt ttcaaaagca tttgaaaatt
    42481 cactgtcagt aggaaatctt tgagatgatt tcttatttat aaaaatatat cttaatatat
    42541 tagaatagtt ttctttataa tcactaaatt ttttaatttc ccttcctaag ttcataaata
    42601 ctttattcag tgcattcgga ggtacatcac atactattct tcttaatata aaacattcta
    42661 ctaaattaag ggattctaca agtacttttt tatttattat accttcatta taatcatcaa
    42721 ataattctaa tataaacgga tatgatacaa atatttcaag tttgtttatc cttttcaaaa
    42781 ctttgtttac atcattatca tcagtacatg aataagatat ctctctataa tagttagaaa
    42841 atttaagtaa atcttttaat aaaatttcta tatctatacc attatctgat acataccttt
    42901 taaaactaaa atatacttta tttttattcg gtatacttct ctcctttata gtcaaatagt
    42961 ctcttataaa actacttacg ttgctacttg tatttttttc aattttatac caataattat
    43021 tataaaattc ctcttgtaac ttagagcttc tacccattaa cacaaagttt cttactctat
    43081 cagcttcact taaatctaag ccagttgaat ttagactttc aaagattaat tgagggtcat
    43141 cttcaccatt ttttaactct atttctacta tagttaattt ctgtatagca tcaaacaaat
    43201 catctattga tatattatct tcttttattc tattataaaa atataaataa tttgaaacta
    43261 tattagaatt tctatctgta ttcatttctt cttcaaatag ttcatagtac gcttttctat
    43321 cttctgctat tggttttaac tttatttttc catctttatc tcttgagtgc ttgtttataa
    43381 gataacactc cttaatctgt tcttctgttg taataattcc ttttgattcc ccaaactctt
    43441 ttattatttg acacatggca atcaataata ttgacacagt agtcactctt tgttgtccat
    43501 ctattattaa atattctttt cccatactat atatagatac aactgaccct aagaaatgag
    43561 ttctaaatcc agaatctatt atatcctcta aatcatcaaa caatctttta cattgttctt
    43621 tcttccagtt ataatttctt tgatatacag gtactacaaa acttttgttt gacccctcta
    43681 aataactaag aaattcaatt tctcctgctt tcatattaac tccccctata agttaaataa
    43741 attccattca taactccatg tatctatata ttatatcaaa attttgactc ataaatgtat
    43801 atgaaagcct tattatatac ctttttatac ctgtttttat tttattaaag taaatacatg
    43861 attattctat aaaatataca aatacttaat tttaaaaatt attatttaat cttcttcatg
    43921 agtaattcat agttatttat caattaaaaa gagatattgc ataattattc aatacctctc
    43981 tttgtatatt tacattatcc atatctagtt atctatttca acccaatatt agactaccta
    44041 ctaataaatt tattctctac atcattaaca ataattttgc actaaataac atcattagcc
    44101 tatctctgat gcattttctt taattttatt tatagtttta atcaatttat ttctctcttc
    44161 aatatgattt tcaaataaat caattatact tccaacagtt ctaaatgggt cttccatcaa
    44221 cactttgtta tcctctataa atccattctt gactacataa tcgactataa gtttaacaaa
    44281 atgtatttgc ttagtattaa agctcttatt atttaaaaac tctgaaaaag cttcatttgc
    44341 agcttctcta tccaatccca ctagtcttct cactaattga cttactggag tatctccaaa
    44401 ctccttctta taatcatcac aattacctaa ctgttttaag agtatttcct ccaacgtttc
    44461 aacatcttgc tttgttatct ttttattatt tcttaattta aatattgcta attcatcttt
    44521 atggctattt aaataatact ctaccttctt tttataattc ttaagattgt ttgcattata
    44581 tacagaatca tttctatctt ctgctacaat catatcttca aaacttgtat aatatatctt
    44641 ttgactagac ttttcaagat acttaataag ctctcttaat gatatacgta cttcttctac
    44701 ctcaaatata tctgaatctt cccaaaaatt ctctgtcatt gctttttcaa tagtatattt
    44761 ttgttgctga atctgtggta tagtcccaag ttttgaaagt ttttctgctg tagccattac
    44821 atgccttata cctttacttg cattattatt ttgtaagtat gcaagttgta tattatacat
    44881 aactacatca aatcttttag ccaattcatc atcactatat gaagttatga gtggtgatat
    44941 atattctctt atctcatttt gtgctactgc tccaatattg ctccaaacat tttcattttt
    45001 atacttatgt acataactta aattcatcct aactatataa ctatcctcat ttaaagcttt
    45061 tacagaagtt ataagttctt ctaacaattc ttttctaagt tctgcatact caccttctat
    45121 atatttaata tcttgaagtt ctttaaccat acttaccttt atattaaata atttttcagt
    45181 aagtgtttct gctttatttc cctcaaatcc tttaggatta aatttaaaaa attcaaaatt
    45241 attacaaaaa tcaaatatta agaatctctc cttatccata tcaacaccta ataaatctgg
    45301 acataatcta gttcctctac ctatcatttg ccaaaactta gtcttacttc tcactttctt
    45361 gaaaaaaaca agatttagta tttcaggtat gtcaattcct gtatcaagca tgtctactga
    45421 aactgctatt tgaggtaatt tattcttatc agaaaaatca tctattatag aatctacata
    45481 atttatacta tagtcaactg cttttacaaa gttcccacca tactttggat acagcttatt
    45541 aaatctttca actattgccc tagcatgctt tgtattcttt gcaaaaatta tagtcttacc
    45601 aatcttttct tctccttcta ttttcaaccc ctctgtcatt agcttattta aaactaaatc
    45661 tattgtgtca gaattaaata gccactcatt tactgcatta ttccctattt cgtctccaat
    45721 actctcatca tcattaaatg tattttcata ttcttccttc tcttcatcag aaagctcatc
    45781 atacttaatt ccatcttcca taatcttagt cttaaactca atactagtat aatctactaa
    45841 atatccatcc tcgactgcct tattatactc ataagcatat gtaggtactc cattttccat
    45901 gtcaaaaact gaataagtat ttttatctat ctcatccttt ggtgtagcag taagacccat
    45961 taagtaagaa tcaaaataat caaagattga cttatacttt ttataaatac ttctatgcga
    46021 ttcatctatt ataattaaat caaaatgacc aggtgtaaac aatctctttc catccttaga
    46081 cttcgtatca tcaattgcat tcatcattgt tggatatgta gaaaatatca tcctagcatc
    46141 ttctgggctg tctttgctat ccaataaatt acataacgcc aagttaggta atagcttagt
    46201 aaaacttttt ttagcttgct ttaccaatgc ttttctatct gctagaaata atatattttt
    46261 aatccaatta tgtcttgaaa gtacatcaac tatagatata gcaattcttg tttttcctgt
    46321 accagtagca cataccaaaa gagttttgcg ttgcttattt tcaagggcct cacatacagc
    46381 ccgaatagct tctttttgat aatatctatt ggatatttca tcatttattg ttacagaact
    46441 taaagacttc ttactctttc ttctatccat cataagttgt aattctgatt ttttataaaa
    46501 tccataaact tttctatctg aatagtcatc ccaaatatac atatcaaaac cattagtcaa
    46561 aaatattact ggtctttgac tatatctctt ttccaaacaa tctgcatata atttagcttg
    46621 ttgttgacca atttttgggt ctttgctcgt tcttttcgcc tcaactactg ctaatggctt
    46681 accattttca ccataaagaa cataatctac atatcctaca ccactttcat taggcatacc
    46741 ttgtacttct atttcctccc ctatatcttt tccaaattcc caacctgcaa gctttaattc
    46801 tatatttata tatctttttc ttgtctcaaa ttcgcttact tcgtctatct tgaaatcata
    46861 gtttacagta ttaacttttc tcttttcagt tagtgacttt cttaattcct cattttcttt
    46921 tattacttct tcaagctttt tatcttttga acttaatctc tcgtaaagat ttttaagttc
    46981 gtctggtctc gtccttttct cttctccatg aagtaataaa tcttcattaa agtcttctgc
    47041 tgtatattca tctgaataac aatagtctat ccaactaaca aattgatgca aattgttaag
    47101 tgaaagtatt gcttctcctc tctctatgtt cgcactagta tgtacagata aattacctaa
    47161 cttaactata tattttaata aaggtaacat atcatagtct ataagttcta taaaactatt
    47221 attatgaatc aacgtactga gattatcttg ataaggcaat actaaatcac tatcattagc
    47281 atatagccat tttactgcaa gctctaaagc tcttcttgtt atagttgcac aagtagatgg
    47341 actaactagt atactttttt ctgcttctaa gcaagcagta ttaaaactat tgaaattttt
    47401 cttcttttgt aaaaaatcaa aattacccaa ggcttttatc ccccttttgt cccttagtta
    47461 aaataaatct ctctaaaaac tatttcttac agctgtttct tatactaaca aatacttctt
    47521 cattttctgt aaacaattcg tacatatctt caaactgtgg tatatcatat ccatgagaat
    47581 catcatttct caattttcta agtgtttcta taactataga agaattttta ggtaataaat
    47641 tgtgatactc acaagctaaa aggtagtcat aaaagttttt agattttatg tttaaatcaa
    47701 ttgatttata atacaacatt gcttttgtta attctagaaa tgataccata tagcttttaa
    47761 agccttcttt tatgtatcta gcccataact caggcatttc ttccttatca tataagattt
    47821 tgaagttttg caggtcatac aagcaagaac caaaatccct atttacttct tctattgagt
    47881 tccaagataa tttgtttcta attaccatac atgtccctcc aatctaagat atctattaca
    47941 tcactgtttt caaaatagaa tttatttata taatccttaa aatctttaga ttcataaata
    48001 acttcacctt ctaaaatagc ttttttaagt gctattgtat aattatctgt aacaattttt
    48061 aggtctacat caatgtctaa tatatttctt agagcttctg tcttagttgc aagttctgta
    48121 attggtactt ttttgatggg aatccaagct atgtctatat cactttctga tgtatgttta
    48181 tctgttccat aactaccaaa tattatgatt gctagagtat tttcttttgg aaatacattt
    48241 attattgagt ttttaatctc atttggtata tttctcattt aatcacctct tgtttattag
    48301 gtaatattgt ttagttaaat aattctcctt tgaaagcttt ttgcattaat gaattaaagt
    48361 tatcttctaa ctcttttaag ttggtttcta tttttaattt taatttatcc acttgcttaa
    48421 caaactcaga aaactgattt tgaaattcaa ttggaggaac cattattaaa tattcaccta
    48481 acttactaac tgataactca atttgattcg ttgaaccatt aacacatttt ctatatattg
    48541 tgtcttgtat atttgtaaat tcaaataacg ctgcaaaata atctgaattt aagttatttg
    48601 aaatacttct taaaactgta acatgactat ctgctatata ttcagaatta tcaattttgt
    48661 taaattttac acatcttcct aatgtcccag ttccagtaga atttattaat atatcatttt
    48721 gtttcaaaaa tatatcttct atcttctctt ttaagttttc atcataatat ttacaatttt
    48781 ctaccttcaa atttctccag tatatacatt tttgatttat aacttttata tttgattgct
    48841 ctacatattt aggagataca cctcttttta aatatataga aatctcttta atcttcttca
    48901 tatcaaattt ttttgtatta ttaattggct ccccaaacat ctcaataaat cttgatttaa
    48961 ctaattcatc caatgcttct atttgctctt ttcttttatt tattaactct tgagctttat
    49021 ttaaaacttc taccatttta ttttgtatac aaattgtgaa atatggtatt tttatatcat
    49081 ttaacttgct tttatttaaa gttgcaccca taactgctct atcagtatta ttaaaattta
    49141 aagttctcaa agcataatat aaatattcag atgttataag ttcattattt tttatttgaa
    49201 agttagcaat tgcttcattt gtaaacatgt cttcttttaa tatggcaact ctacctatag
    49261 acaacttaaa actcattaca acggtatttt taggtactaa tttcatatta gctttttcaa
    49321 cagctaaatc tgttatctct tcttttgatt ttgatatata tttttctttc aaatcagaaa
    49381 ttgataacca tctattacca cttccccaat aatcagaagt atttctagat ggtgttttgc
    49441 caatatttat atagcacaat tcatttaatt ttatatactc cataccctat acctctaaca
    49501 ttctttctaa ttcttctaat ccaacagcta tttccttctc taactcccta actctaccta
    49561 taatcacact aggagcatca taaactactt cctcatacac tacctcttta tacttattaa
    49621 tagataaatc atacccattc tctcttatct cttccacatc aacaaaaaag ctttgttctg
    49681 ttctttttct atctacttcc ccatcaagat tatcaaatct cttaataata tcctctatat
    49741 cactatcctt tatctcattt ctcttatcat ccaaagaata accatcagct ttcatatcat
    49801 agaaccatac cttatcagtt ccacctgtcc ctgttttagt aaatatcatt atagctgtag
    49861 atactcctgc ataaggctta aacactccac ttggcattga tattatagct tccaatttat
    49921 gattatcaac tatttctttt cttatcgatt tatgtccacc tgttgaacca aacaatactc
    49981 catctggcac tatacatgcg catcttccac caatttttaa aactcttaaa aaaagtgcca
    50041 agaataataa ctctgttttc tttgtcttag tcacttttaa taaatctgct gacactgctt
    50101 cataatctaa acttccctta aaaggaggat ttgctaacac caatgtaaac ttatctttat
    50161 ctgtattaac ctccgataaa gaatccttat actctatatt aggattgtca acgccatgca
    50221 acatcatatt catagcacct attctaagca tagttctatc catatcaaat ccatagaaca
    50281 taccattatt aaaatgctcc ttcagccctt gcactaagaa aagacttgaa tgattatccc
    50341 ttaagtattg ttgtgatgat actaaaaaac ctgctgaacc tgctgccggg tctactataa
    50401 tatcttctgg tgttggttta ataagtctta ctatcatatc tattatgtgt cttggagtcc
    50461 taaattgacc attagtacct gctgtagcca ctttggataa taaatactca tacaaatctc
    50521 cctttgtatc tctatcctta cttaattcta aattactaat accatcaact attttagata
    50581 acataagagg cgtaggaatt ttaaatattg catctcccat gtactttgca taagctgagt
    50641 ctttatttcc atgtaatttt tttatgaaag gaaacacttc attttgtact atttcataca
    50701 ttttttctga atttccttca ttagaaaact tactccatct taaatgttga tgttcatcat
    50761 caaatatcct ttcaaaagaa actcccaaaa gagttgcttc tgcttcattt tttgtttcta
    50821 cttcatccaa tcctttaata aataaaagat atgtaaattg ttctataact tctaatggat
    50881 tagttaatcc accagtccaa aatgtctccc aaatcttgtc tactttgctc cttaattctc
    50941 ctgtaatcat atatgacttt ccctccagtg ttcataaaat aatttaaata tatattttag
    51001 tcgtacgcct taataattag tgtcttatat taaattcaaa attttactac acagttatta
    51061 aattattttt cctatttaca tgttttagtt aaaaaactaa tgcaatactc ttattttatg
    51121 attattatac atcccataca aaattatttt atcatatatc cagcatagaa gtcatctacc
    51181 tggataactc ttaccatatt ataacttttt aatattaatt taaacttaga aagaaatttt
    51241 ttatttaatt atatcatctt ccttatttca aatttctcaa ttacaatctc aatcaaaaaa
    51301 taaaataaga tgctgtctca aaatagatat aatcttcttt tttattttcg gaatgatgaa
    51361 aatatattta atttcataca aaaaagagtg cctcctgaac taaaaagttc attttgagac
    51421 accccttaat ttaatcttac ttattctctc cctttattat taacacttca ctatctctat
    51481 tgcttttcct acacatccac aaacttccat cctactctta acaaaatctt taactgactc
    51541 taaacctttt ttaccatatt tcttagggtc aattacctct gggtcagaat taagcacatc
    51601 cttaacccca ttgctataag caatccttaa ttcagttgca taattaacct tgcaaatccc
    51661 tctttttata gattccttaa taacttcatc tggtattcca gacccaccat gtaatactaa
    51721 tggaactgat acaacatctc taatttcaga taatctatct aaatcaagct ttggctctcc
    51781 cttatataat ccatgtgccg tacctattgc tactgccaaa gatgataccc ctgttctctc
    51841 tacaaactct tttgcttcta atgggtctgt atatgctccc ccatcaccac catctaaatc
    51901 gtcttcctta cctccaactt tacctaattc agcttcaaca ggtatatctg aaggcataca
    51961 tgcatctaca acagatttag atattgaaat attatcttcg taactttcat gagaaccatc
    52021 aatcataata gaagtatatc caactctaag tgcctgcata gctagtccaa agcttgaacc
    52081 atggtctaag tgcattgcta ctggaacact tgccttctct gatgctacct ttacattcgc
    52141 taaataataa tctagccctg catactttat tgttgaaggt gttgtttgca atattactgg
    52201 tgatttaagt tcttcagcag cctctattac tgccataacc atctccatat tttcaacatt
    52261 aaatgcacct actgcataat gtccttcttg tgcatctaat aatatttgtt tagttgtcac
    52321 taatgccata atttctcctc ctatatgttt atactgattt gatttcttcg ttatttaatt
    52381 ttgctactat ttctctactt gttttgctat ttaataactc atttaaaaat tcttcattca
    52441 ttaattttga agatagttga gataatgttt ttaagtgtaa attatcacca ttatctgtag
    52501 ctgctatcat aaatataata tgtgctaagc ttccatcttc tgattcaaag tcaaaccctt
    52561 cttttgatac acctactgct acacgtggta cctttactgc atctgttttt gcatgtggta
    52621 tcgctatccc cataccaaaa cctgtagatg atatttcttc tcttttaagg atttcttctt
    52681 taaacttctt tttatctaaa agaacactag atttatcaag tattccaatc atttcatcaa
    52741 ttacatctgt tttatttttt cccttaacat ctaaaattac tgtttcttcg ctatataaag
    52801 agatattatt agatacgttt tccgattctg cactttcatt tttatgttca tcttttgtta
    52861 catttgtatt ttctatagta tttttctcat ttactacttt aggtgtaacc atcatataaa
    52921 gtacagcacc tactaatgaa cctacaaata tacaccctac ccataaaagt ggcttattga
    52981 ctaatcctag aaccaaaaac cctccatgtg gagctggtac ttctattttc attatataag
    53041 ttaaaattga tgatattgat gatgcaatca taagtactgg caacactttt aatggatttt
    53101 ttgctgcaaa aggtattgcc ccctctgtta tatgagtact acctagtata taattgatta
    53161 atcctgctgc tctatcttct tctgtaaatc tatttttaaa taaagtagat gctattgcta
    53221 ttaccaatgg tggtgttata caagctgcag atacacctgc cataaataaa taatttccct
    53281 gtcctagaag catagttcca gttacatatg ctgctttatt tactggacct cccatatcaa
    53341 atgctgacat acatcctatt actattccca aaattatagg gcttgaattt tgtaaccccg
    53401 atagaaagtt catcatagca ttgttaagtg ctgaacatgg cccaccaagt aacaacattg
    53461 ctacacccac aagacctacg ctgacaatag gaattataaa aatcgattta agaccttcta
    53521 attgtcgtgg taattttctt aacaaatgta caaatagttt aactaagtaa cctgctaaaa
    53581 atcctgatat gattccacct aaaaaccccg aacctgtatc aaatgatatc attcctccaa
    53641 caagtcctgc taacatacca gctcttcccg atatagattg agctataaat gctgccaata
    53701 caggaaccat caagttcata gaatatccac caacagattt taatgtagct gctatttgat
    53761 tatattgttc tgaatttggg tcaaatgaat aaatccccca taaaaatgat atagcagtaa
    53821 gtactccacc tgctactact aaaggtaaca tgtgagatac accattcatt aagtctttat
    53881 acaacttttg accaaacgat aaatttcctt cttctgcaat tttactgctt gataagtttc
    53941 cttttctaat agctactttt ccatcaatac atctttgtat aagttcatta gctttatgta
    54001 taccttcttt gacaggtact tctattactg gctttccatt gaatctgtcc atatcaacat
    54061 ttttatcaca agcaactatt attgcatctg ccatttcgat atcttttgct gttaacttat
    54121 tttctacacc tatagctcca ttcgtttcaa cttttatgtc acaccctaat tccctggctg
    54181 aattttttaa tgcttcttct gccataaaag tatgagctat tccagttgga caacctgtta
    54241 cccctagaat cattttcttt cccattttta taccaccttt ctgactctta tattttttat
    54301 ataatcttcc acattctcca aattacctat accattactt tcagccacac ttgctcctgt
    54361 tgctgctgac ctttttaatg cttcttcaat atgttctgga ttttccaacc atatacttaa
    54421 aaaagcagct aatgcagaat caccagcaca tgcagagctg actactgtaa ctggttgagc
    54481 actagcataa taaattgatt ttccattata aaaataagaa cctttttctc ctaaagttag
    54541 caatatattt tgagcacctt ttaaatgtag taatttaagt acatccttaa tatcttcttc
    54601 atctcttaca ataattccaa atatatcttt gatttcttca tcatttggtt ttatcaaata
    54661 tggattatac tgtagtaact cctttaattt tggtgaactt atatcgagta ttgtctttat
    54721 acttttattt ttacaaattt taaatatatc ctcatagtaa ttatcatcaa taccaggagg
    54781 tagacttcca cttattgata agtaacttat atctgctaat gactgtatct tatctagcat
    54841 atctagtttt tgtttttcat ttacatatga cccagagttt acaaatttaa attcatcact
    54901 tccatcattt aaaaatatat ttatacgagt tgtatcttct acccaagtag gcaatacgtc
    54961 aaatcctctc ttttcgcttt cttcaactat atattttcct gaaaatcctc caaaaaatcc
    55021 taatatctta gattctatac cataatgacc tagtacaaaa gttacattta atccctttcc
    55081 attaggagaa tatacagcat ttgatgtacg atttactaat tttctcttta tcccattagt
    55141 agatatattc atatctattg caggatttgt agttaatgta tatatcattg tcttccccct
    55201 tgcttgtgct gtgtatgttt tcattataat aaaaaagtct atgaaaatct tttcacaaat
    55261 agaaaatcga ttttcataga cttttcaatt taattttcag aattattata tctgaccata
    55321 taatctataa ttatcctaga tataatatac aagggcaatc tggaagatac ttcatattca
    55381 gaaattgata tatgttcatg tttgtatcct acaatatata aatccgaata ctttataagt
    55441 tttgcacttt cactacaaca gcaagttata accttagctc caactaaatt ggcattctgt
    55501 gctgattcta caagctctat ggtatttcca ttcaatgaaa atataattat aagttcgtct
    55561 ttttttattg atttagattt tattttcatt atgttggggt catttataaa aacaacatta
    55621 aaatcaagta attgcaattt aagactaaac tcttttgcta catattcagt aagccctctt
    55681 gctaaaatat atatcttact agatttattt atagttttta ttatattgat tagtgtagtt
    55741 aaagatattt gttctataac tctctgtgct tctataaagg atttatttat tatatccccc
    55801 atattttgta tatcatcatt ttcatctttt actgttaatc tatacctaag ttcattgaat
    55861 ccatttaaac cacattttct aattgctctt gaaacggttg ctggagatga atatgtttca
    55921 tgagcaatct ctactataga taattctggt aatattgatt cattttcatt tataaattta
    55981 attatttcaa gttccgtctt cgttagattt tcagaattac ttttgtttag ctcaattatc
    56041 atatgttatc tccccttata taagttttat ttgtctaaat ttatcgagta atataatata
    56101 ttacctctta actacttatt tttatataca attaagattt agtcaatgtc tatatatgta
    56161 aatttataat ataataattt tttgcttaaa gtttattatg ttatcttata gcattttaaa
    56221 ataaaaaaga attgtacctc taccaaaatt tggatgaagt acaatagata ttcctcatac
    56281 tgatatgttt atgattaaaa gtataaatat aaatttcgct atgaatcata taattaataa
    56341 atcattttat ttacaattat aacccccctt ataaaactat attaataata tatacagtat
    56401 ttataagggg ggttgtttat atttaaaaac tatttacttt tctcttaatt cttctccatt
    56461 agttcttatt acattttgat accaataaaa actatctttt ttataacgtt ctttacttcc
    56521 atttccattg ttatctatat ccacatatat aaatccatat cttttttcca tttcttgaga
    56581 tgaacaactt actatatcta ttggcgacca catacaataa gctaatattt cggttccatc
    56641 agctatagct tcacctattt gttctatatg ttttcctaaa taatctattc tgtaactatc
    56701 atgaactttt ccatcttcaa atttatcatg cattccaaat ccattttcag ctatcattat
    56761 tggcttttgg tatctatcat aatattgaga taaagtattg tataatcctt ttgggtcaat
    56821 tgcccacccc caaggatttg cttttaaata tggattcttt atattgtcag ttggattcat
    56881 ggtgttttta cttgctgata ctgttgtaga ataatagtat gataaagcta gaaaatccat
    56941 agtattttct tttaagattt tatcatcacc ttcctccata actatattta tgttattttc
    57001 tttgaaaaat ctcttaatat agactggata ctctccccta aaacttacat cagtgaaaaa
    57061 atattgtagc ctatttcttt ttaaagcaaa tactacattt tcagggtcac aatcttctgg
    57121 ataagatgta caatctgcca tcatcatacc tatcatcata tctgaattta tttcttttcc
    57181 aagcttctta gtcaaagctg tagctatgaa ttgatgatga atagcttgat atctagtctc
    57241 ttctacatta tcaacttggt ctacacaaaa tgcaactgaa ttaaatgatt cataatgtat
    57301 taaatttatt tgatttataa ctatccaata tttaacttta tttttatatc tatttagtat
    57361 taattctgca tatctaacaa agaaatctac cacttttcta ttagaccatc ctttatattt
    57421 taatactaaa ttcaaaggag tctcatagtg aagtagtgtt acaataggtt ccataccatt
    57481 atctattact tcatttataa gattatcata aaactttaat ccctcttcat taggctctaa
    57541 atcatctcca tttggaaata ttctagccca atttattgaa aatctaaaac actttaaccc
    57601 tagctctttc aaaagcttta aatcttcttt gtatgtatga taaaagtcta ttccactacg
    57661 cttaggataa tatccattat tatctttcat agcaaacttt attctttcta tagtcatatc
    57721 agactcataa ggtttagata tatctctatc tttatcatac atatgtacat cagctaaaca
    57781 ccaacctttg ccaccttcat tccatgcacc ttctaattga ttagctgcta cagctcctcc
    57841 ccataaaaaa cctttaggaa acttacccaa tttaatcact ccttatttta tttatttaaa
    57901 tcatttacta ttatttacct tatattctat agactttact attcctacta aagacatagt
    57961 tatatttaac tcgctgaata tggtcataag agtatcttga gcatgtgcaa ataacagcga
    58021 atgtgctctt ttctctccac cagcttcccc ttgtataatc ttggtttgag ctctatgtgc
    58081 ttctgtcata aacccttttg ctttagctag ttttaaatca gcatttctat aatcaaactt
    58141 ttccaaatca ttaagagcat gtttaatttc tgttctagcc tcacctgcac gaagtattat
    58201 ttgcattgct acttctacta attcttcatc tattatatgt tcttcaattg tcatatttat
    58261 aatttccttt caatttctaa atttaaacct cttgactctc taattttatc tcttctttct
    58321 cataagcttt aaaaaatgga taccatatca taaatagcaa tactatattt attgctaaaa
    58381 caataagacc tctaacatct tgatttacca taaaagtaga tataccaaaa ggaacatacc
    58441 ataaattaaa caccttactt ggaattgtaa caaatcccat actcattgat aaataagtag
    58501 ttattgatat tactactgtt cctatccaca taggtaacat taaaaatggg ttccatgcca
    58561 ctggagctcc aaatattact ggttcattta tattcattat agaagggaca atacatgctc
    58621 ttcctattgc ttttattctt ccaactctgg ataaacacat cattataact aatggtaatg
    58681 tagcacccaa ccctcctaaa gttatccagc ctgtttgaat aacttcgtaa acatatatat
    58741 tagttgctac tcctcctgat gctactgctg ctgcattagc tgcaattgca ccaagttgaa
    58801 ttgaataagt tataggagat agtacccacc cacttattcc taaagaatat ataaatacta
    58861 ctaagaagtt taagagtaca aatccaggta atgtctgtgc tatatctgat actggtttaa
    58921 atactctaac tattatttca aacatgtcaa agttgagtcc ataaattaat ccccagccta
    58981 caaacattat cactgttata ggtaacatat tatcaaacca cttgcttaca aaatccggaa
    59041 gtgctgaatc ttctccgaaa aatgaaaaag aaccaaataa agacattatt aatccagaga
    59101 ataatcctgc aactagcgat acaagcattc cttctcctcc aaacctgttg aagttaaata
    59161 tagctccttc attcgtaatc tctggacgaa tcatcattaa cattaatcca gcacctgcaa
    59221 gaccagctac tacactcata ctttcaaatt tcttattctt cattgtttcc ataggcaata
    59281 aaaatgctat aaataatcct aaaagtccaa atgtatattg atttattgga cttaaatcag
    59341 gtaaaaagct tatgtaattc ttcaagacag aaactatagt tactaatgag cctacaaata
    59401 ccattggcaa aactttcatt atagttgatt gaactgattg tacccatata ttcttagtca
    59461 tattatttac aacaggagta aatttttcac ttaaaaaatc tataaattta ttcataaaca
    59521 ctctccccat aaatatttta tttgtttgat attagttcta gtgcttcttc caaagccttt
    59581 gcaccatcta gtcttccata tgcagtttta gatatacatg ctactggaac gttatattca
    59641 ttagcctttt gttgaatttc ttccttcata taatctaaat gtggtcctag taataaacaa
    59701 tctatttctg ataaatactt atctatctct gactcacttc tcgcttttat atctgcttct
    59761 ataccttttt tctttgcact ctttctcata ctagttgcca taaaacctgt acttgctcct
    59821 gaaccacacg ccaaaagcac tcttatattt ttcataataa tacctccaat atttttatcc
    59881 attaatttat ttcttaatga actttttatt ttattatgtt tatattttac ttcccaaata
    59941 agttcatttc acataaatat atttcctaat aataggaaat catttactct taattagacc
    60001 tattaatata gtataatgta tcttataata cgtacattca attatataat tatcatatca
    60061 tacagatttt attttaaaac tatgcgaggg aatctaatga aaacatctaa aaaagagcta
    60121 tttttaaatt tcataaaaac gcaacatgat tggatagatt catccacatt agctaattac
    60181 cttaatgtat caacacgttc gattagaaaa tatgtaaacg agattaattc taatggtgca
    60241 tttatattat cttctaaaaa gggctataaa gtaaatctca atactaattg tcaaactaag
    60301 attgatagtt cagagaatat atcacctgat aacagattaa atttaatttt aaaagaactt
    60361 atagttaata gtaatggaat taatatattt gatttaagtg aagaattatt tgttagccca
    60421 gctactattg aaggggatat agtcaaagct aataaattta taggaagtta taatttaaag
    60481 ataaagcaat cgaaattttt attgaaacta gttggaaatg agtctgcaaa gcgcaagtta
    60541 atgagctcta taatatttaa agaaacggga agtgattttt taagcttatt tgatgtacaa
    60601 aaaatatatc aagagtataa tttgactaaa ctaaaagaaa atataatata tatattaaaa
    60661 aaatacaatt tatttataaa tgagtatgct ataaacaaca tacttcttca tttaatgata
    60721 actatagaca gaataaaaaa gaataattac atagactctg ttgaagtagt aaactacata
    60781 gacaataacg tagatataaa tattgcaaaa gacatatcaa attttttaga atctgaatac
    60841 aatataactt taactagtgc ggaattatac tatttagtat ttcagttaac aaacaaaact
    60901 acagtcttaa actacaatca aatggatact aaatcattgt caaattatat agatgaacac
    60961 tttgttaaat taactaaaaa aataattaaa aatgtatatg acttatatct tatagattta
    61021 tctgatgagg aatttgttgt aaaatttact cttcatgtaa aaaatttaat cagtagagcc
    61081 aaaaataatc aagttttaag aaatcaaata cctcaaaagt taaaagattc ctaccctttg
    61141 atatatgata tatctgttta tatttgcaat cagattcaaa ctttagaaaa tgtagatata
    61201 gacgaagatg aaatatctta tatatctctt catgtaggtt cattctttga tagacaaaaa
    61261 ttattagaag ataaagttct atgtgcatta attactccaa attactatga tttacaattc
    61321 aaaatagtaa gagaccttga gaagagattt aatgaatcca tagaaattat tcagattttt
    61381 tcagatactc ataatcttga ttttgacaat aaggtagaca tggttattac tactttacca
    61441 attaacgata gatgccctat accttttgtt tatgtaaatc cttacctaaa tagaaaggat
    61501 tatgataata ttcaaagtaa atttattcag attaaagata gaaaaaatat acttactgta
    61561 caaaatcatt tagaaatgta ctttagtgaa tctttgttta tgaaaaatat atatttagat
    61621 agtgctaaag attatataag atttatggga aatattctgt acgaaaataa atatgtcaaa
    61681 cccaattata tagatgatgt tcttataaga gaaaaaatgt cttcaactgc atttaataac
    61741 aatgtagcaa ttcctcatag catgaaaatg gatgctttaa aaaccggagt atgtttaatt
    61801 gttaacgata aaccagttaa atggggtgag gaaaaagttc aaattatagc tatgatacct
    61861 ataaatgaaa aagaaaaaga aaaattcaat tacatatttg aaagctttat tgaaatatta
    61921 tctgaatgga ataatgttaa agaacttact aaggcagata actatagtag ttttatgaat
    61981 agaatagctt atcttattca aaatatctaa atccattaat ttatttccaa tatatgtttc
    62041 ttaagttatt aacataaaat agataagctg tcacactaaa aagtctaaat taatatgtga
    62101 cagcttttta cctaatatac cttgttttaa tactacatat tttttgactg ttgtatacta
    62161 gttataagat tgaatatttg tgttgttgta gctgtcatat tctcactagc agttgcttta
    62221 tccattgctt cttctattgt catagctcta tttactatag aaaaataagc atctataccc
    62281 tcttcattac atttaactgc atcttctgtt gtggctccag ccaaacctat tacttttacc
    62341 ccatattttt ttgccagttt tgcaactcct attggagcct tgcccatagc agtttgattg
    62401 tccaatctac cttcaccagt tatgacaaaa tctgcatctt ttaactcttc ctctaattta
    62461 atttcttcta atattatttt tattccagat tctaattttg aatctaaaaa tgctaaaaaa
    62521 gcaaaaccta atcctcctgc tgctcctgct ccttctacat tagctacatc tttacttaag
    62581 taatttttaa ctactttgga aaaatttcta agcccattat ctaacttctc aattatttct
    62641 gatgttgcac ctttttgaga cccgtatatg tatgcagctc catttttccc aaacagcgga
    62701 ttatttacat cacaggctat tttaaactta cattcatcta attcctttaa tctattttct
    62761 atttttatat gtcttatttc atttaaaact tttccaccta atcctactaa cttgttattt
    62821 ttatcataaa actcaaaccc taaggcttga agcataccta tcccagcatc attagtagca
    62881 cttccaccta tcccaactat aaaatttcta tagcctttat ttattgcttc ctttattatt
    62941 tccccaacac cataagttgt agtgtataaa ggatttctaa gttcagtcgg aaccaatgtt
    63001 aatcctgatg cttgagctat ttctattatt gctgtacttg tattttttaa taatccatat
    63061 gttgcatcca cttttttagc tattggtcca gtaacttcta tagtctcttt tttaccattc
    63121 atcccttgaa ctaaagcatc tactgtccct tcaccaccat cagcaagtgg caatatcttt
    63181 acttgcgcat cttctttaac cttcaatatc ccctttttta ttgcatttcc tgcctctatt
    63241 gaagataagc ttcctttcaa agaatctata gaaattaata ttttcatact tatctactcc
    63301 tttttattac tccttatttt aaacatataa ttttataagc ttaatttatc ttttatttta
    63361 tactctacat ctctctttgt atacaactta taccattaat attcttttat cttataaaaa
    63421 gggagtgtct caaaataaat ttcttagttc atgagacact cttttgtata aaatcaaata
    63481 tatgtttatt atttcaacaa tgataaggag gattatctct attttaagat aattcctttt
    63541 tagcactatc taatcatttt tagcactatt taaccagtat agttttaact tggttcatta
    63601 agcactctac atttacagag ttattatcta ttgatataga ttctaattct ttttcattta
    63661 ggttaatcca tttagctgtt ttaatatttt tgttaaatac tatgttagct gattttgttt
    63721 cttctttaga attataaaat ctaactacta atgcctcttc tttttcagcc ttttttacaa
    63781 cacttaacac aaggtcctta ttagtttcct taagtaaact atatgaataa tctacttcta
    63841 tttctgattg attcaatttc atagcattat atggcatttt attataagtt tgtatttttg
    63901 ttaaatactc tttagccata tttgcaacat ttgcttctag tgtagatttt tcatgagtaa
    63961 ctattgctaa gtctattttt atatctccta tcatttgaga atctggagta ggcaacttta
    64021 ttcctgatgg acgacctggg cgtcttgcca tttcttcttt acctaggaat cctacacttc
    64081 taaataatgt tatagctatt gtgtcaaatt tttcccctac tatttcaaac tctcttgtac
    64141 tgtttgtaag aacagctact ccatgctctt tgtcagacaa tccaacgaat gttagcattg
    64201 gatatataga atctggtctt tcactccagt cttcctgttg ccaaacttcc atagcatcat
    64261 catacacact tctctttata tgtccaaact gattatcaga cacagaaaac tttgaagcta
    64321 tatttgttgg tatataagtt ctaaccctac aatctcttgc ttggttattt atgttgaata
    64381 ctacatctat tatagcttta tcatttggaa catttataac tatatcaaag tcaataaatg
    64441 aatctgctct attatttttt ctagcttgta tatcttttgg tacttttaat ctataattta
    64501 tctttatctc attattaaat ctatttttct ttatagtgga atttgctact atattatcgt
    64561 taaatattaa tttctcattt ggaagtggtg aaaaatcata ctcatctcct tcatctcctc
    64621 cattttccat caataataca ttttcaaaag ttttatttaa ttttttatca aatatcttta
    64681 atgtcccgtt ttcattaact tgaatagtat aaaagtcatt atctaccatg tcacatactt
    64741 cataagcttt ttctaacata tgttcaactt cttttatcat atacgcctta taccccattg
    64801 caggtatttt atctttaaag tttattgtat ataccataaa tgaatcatag tttccataat
    64861 gaacaatttg acggtctatt aatcctgcat ctattacttc tttatgtacc acttcaaaat
    64921 ccaacttatt attatcttta tcaaatattt caaatgcttt cattttagtt ataacttggg
    64981 cgctcactat ttcattccta tcgtaaggca ttaagttaaa tgctattaac ttatctaaag
    65041 ccatttcaca actcattgca tcaactattc ttcttttgta aaatgttatt aattggtcta
    65101 ctttttcctc agctaagaaa aatctattca ttatttcctg gtgaacttta tctgaacaac
    65161 aacatccaat gctgtcatga gcatgatttt tcattatttc tttccaaatt aactctatta
    65221 atccatgatg atattcaaat cctagagaat atgcaataga agctagtggc tccaatatgt
    65281 tagttatctt tgattctatt ctagcatttg ctgattttat atccattctt gttgagaata
    65341 tacttctatg aaccctcata tatttcccat ctaaaaattc cccttttatt gtatctatat
    65401 cctcattttt ttctagctct ttaaatatgt tttcatatct acttaagaaa aattttctgt
    65461 ctggataaca ttcttttaat ttatatataa cttcaaatat attcttttga attggcattt
    65521 ggtcatgtcc atttggaagt attatatggt cagtagttgc acccttatca agaaccggta
    65581 aatatttatc cattcttgtt cttagctcat cttcattcat tggtagatat tttcctattg
    65641 cataacctaa tggaagtatt tgaaccaaaa cagaagaccc atcatcactc ttccaattaa
    65701 actctgtttt attagttcct tttctttcag aacatcctct ccaaaacatt gaatatttta
    65761 tatcaaaccc atttagtatt tgtggcattt gagcactttg accaaatgaa tctggtaaat
    65821 atcctatttt catatattct ccaaattcat cacaatcttt tattccatat agtaaatttc
    65881 taagtatgga ttctccacca actaccattt catcagtttg agtataccaa ggacctatta
    65941 ttagccttcc ttcttgaact aattttttta ttctctcctt acattcaggc ttaactgcta
    66001 aataatcttc taatatagca gtttgaccat ccatcacata atatggatag ttatgattat
    66061 tttctaacat atccattatt tcttccatat tatttacaag taatattcta gattcctcag
    66121 ttgagaagta ccattctcta tcccaatgca tatgaggaac tatgtgtaca ttttttttca
    66181 ttgcttatcc tccaaaactt atctgataat attttctgtc taattaaaaa tccaataaaa
    66241 atactactga gtttacaaaa ttttttaata tttattttat cactataatt aaacctttga
    66301 tttaaatatc taataacgta tcttttaatg tatctttctt tgattttttt gtttcctagt
    66361 tattattaat aatattgctg atattatagc tccaagtact gccgcaaaga accatattga
    66421 tgctataata aatcctgaca tacttccctc taaaagcgcc aatgagaata tccccgctcc
    66481 aggcacttga agacctatat tgaagaatgc tactatagac ccagttatgg ctgaaccagc
    66541 taccaatgat ggtataacac ggattgggtc atctatcata aatggtattg caccttcagt
    66601 tattccagcc aatcctaata tccaagtttg ctttcctatt tccttttctg attctgaaaa
    66661 taaatctctg cctaaaacag tagctattgt aactccaaaa gctgaaacca tcttaactga
    66721 tgcaaatatt gcataaggta taaaatttcc acttgctatt gctcctattg caaatgtata
    66781 ggctgcttta tttattggtc cacctaagtc aaatgaaacc atagctccta ttattgcacc
    66841 tagtagtatt gcatttactc cagtcatccc atttaaccaa tttataagac cattgttaag
    66901 tgctgctaca ggctttccta ctacaaataa catcaataaa cctactacca aagaaccaac
    66961 tactggatat acccaaaaac ttacgaatcc agctaatgtg cctttggctg gtatattctt
    67021 ctttaaaaat tttactatat aaccagcaag taaacctcct aacatacctc caagaaatcc
    67081 actacctatt aaatcagctg ctagacctgc tgcaaatcct ggtccaagac ctggtttttc
    67141 agctagtgag taagacatat atgctgataa tactggaacc atcaatgtac ctaacatacc
    67201 tccagaaagc tttcttaatt gccataacca agaaccttct tgattgtata gttcttgtag
    67261 accaaatgct tgagatgcta atactgcaaa tgcaagtatc atacctcctg ccacaataag
    67321 tggtattata tgagatactc ctgtaagtat tgctgatttt acatcttttt tccatgatga
    67381 tttttcacaa tatgatatat cagatgattt ttctatataa tcacctttac cttgtttttg
    67441 tgctacttct aaagcttcgt atattatttc ttttgctctt tttagtggag ctgctactga
    67501 cgtttttatg tttggcaaat gttcaaatct ttctgtattt ttaggtgcta catctgttgc
    67561 atatattatt gcatctgccc tttttattat atctggcgta tgagggtcca ccataccatt
    67621 agctccttgc ttttctacat acacatccac acctatttct ttaccagctt taattaatgc
    67681 ttctgctgac atatatgtat gtgctatacc ggcagggcat gctgttattg ctaatataat
    67741 tttttttgat tcattttgaa tcctaatctc ttcttttatt tgttctttct tttcttttat
    67801 atctaagtta ttaaataact ctttcttagt ttttgaattt aacaacatat tcatataatc
    67861 ttcatttgac agtctagtaa ctaactcaga aagtatttgt atgtgtgtat ttccaccttc
    67921 actttctggt actgctatta aaaatattag ctctacttta ttatttgggt ctacgctttc
    67981 ccaattttct attggtgtct ctaaggtcat agctgcaaat gcagcttctt taactgactt
    68041 agattttcca tgaggaattg caagccctct ttcaaaacct gttggagata aagtttctct
    68101 gtacattaca gcttctaaat attcctcata agatgttaac ttgccttcat catatagctt
    68161 tcttgctaag aactttattg cgtcttcctt tgtttttatt ttttgtttta aaaaaacaag
    68221 gttttcattt gtgattttct taaattccaa aattacgccc tccttaaatc atttaatgct
    68281 atgaatatag cataaaataa attatgaaaa tgtttttttg aaattataca cacaatttct
    68341 tcttaaaaaa taaagatttg tgtatttata cacaaatctc tatcttaacc aatattgctc
    68401 tattattgct ctcataatca tcataattgg aaccttatct gatatattgt acccatttac
    68461 ttgtttaatt gttgaatagc aatataaact tatatctgca atttgttgca attgattttc
    68521 acatatatgt gttaaagcta ctaccttaca acccttatta actgctgtct ttgctgcttc
    68581 tataacttct ttcgtttctc cacttaaact aagtgcaaaa aacatatctt gttcacctaa
    68641 ttttcctata tcatgaagta cttcatgtct ttgactatag taagttatat tatcatgccc
    68701 acctctaatt tcttttacta atatctcaca taaaggaatg ttttgaccta ttccataaac
    68761 tataatactc ctagattttt gaattatatc tgctacttta tttatttttt cataatctat
    68821 tagctctaat gtctttttta tatctgattc aaaaccattt tttggctctt tatcctcatt
    68881 ttttaactct tcttttaaat tattttttag ttgagagaaa ccatcatact ccattttttt
    68941 acatagccta actatggtat ttgggacagt aaaaaattta tctgctaaag attgtattga
    69001 taattttact atttcttctt tgttttttct catatattca attatcatgt cttctgtatc
    69061 tgtaaattta tactcatatt tttttgctct ttcataaaat tccatagttt ctcctccatc
    69121 tattttatta ttcataagta aaattcaaaa atattagcta aaattttcgt taatataatt
    69181 ataatttaat atttttaatt tattaatgca tactactctt tttattatac ataaaaaatg
    69241 tgtacttcct atattgatag agatgattca agtttttatt ttgatacatc tctatcaata
    69301 tttttttaga aaatacacat ttttttcaaa tacttatttt taattaaaac tttaggtaat
    69361 ctattcttta tatataatta ttagacttga aaatatcttt aaaatcaacc aattcaatat
    69421 tatttctttt taaccacatt ttaacttcct tatcacatag cattgcatgt tcatatactc
    69481 tctcttgaat aagagaagat gattttataa gactataatc tataaatcct ggatgagtaa
    69541 ccatcaatgt tatatcttta tctaaattta tatatttttc ttcaaataat ttaacaaaag
    69601 atttatttaa cttgtaaaaa tcattctgag gatatttact tggcatgcta atacatgaat
    69661 ccaaataata gggacaactt ggtataccgt attcttttgc agcatcacac attgctgata
    69721 ttgatacatc ttcttctata ccatgtatat caatatactc aggcaattta ctcatataca
    69781 acttgtaagt ttcaatttga gcacaaactt cttcatatac ttcttcataa ttaaaaacct
    69841 ctttacctgt cagtagttgc gttcttctta ttttgctaga aacaaatttt ccaccttcat
    69901 ctaacaaatt ctttatctta atatgttctt tgcaacaagg ttctcctatt actaaattaa
    69961 catgtaaacc aaaacataca tcatcatttt ttaccatttc tatagcttgt cttgaaaaag
    70021 gcatattcac catgattcca gcacttgtaa caataccgtt cttataagaa gatattatcc
    70081 ctagtgtaac accttctgaa tatcctatat catctgccct aactactaat ttcttcattt
    70141 tatgcatctg cctgctttct caactcatca agttgcattt ccatctcatc ctttacttta
    70201 acaacatccg ttcctatgat gatttgaact gatgtattac tcaatttaat tacccctttg
    70261 gctcctgttt ttttaatatt atcatcattc aaaatagtgg catccttcac ttctaaacgt
    70321 aatctcgtca tacaattatt aagagtcact atattttcat aaccaccaca atttttaatt
    70381 atctgtttag ccatatatga aaaattacca tgagaaagtt ttaaattctt ttctttttca
    70441 ctaactttat cacctatctc tatctcaact tcacgtcctg gtgtttgcac attatctttt
    70501 attattatat atttaaatgt tacataatat aatacaaaga atacaactcc tacaggtata
    70561 actaaccacg ctttatctcc ataactaaaa cttaagacat agtcaattat acttgctcca
    70621 ttaaatgaac ccaagcgagc acccaataaa tatagtacaa ctccacctag accagaataa
    70681 aaagaatgaa ttatatataa ctttggagat gcaaataaaa acgaaaattc tattggttca
    70741 gttactgttg ccataaaaga agtcaatgct ccagcggtca ttgcaccttt tacttcttgc
    70801 ttctttttat cttgtgctgt tttatatata gcataagaaa tagcaggtat tgaaaacatc
    70861 ataattatgt aaaatcctgt ccagaagaat cctgcatttg ggtctcctgc cataaatcta
    70921 ggaatttctc ctcttataac ttctcctgtt gatgttgtat attcacccat ttcaaataat
    70981 atgtaagcat ttaaaacttg atgtaaccca gttggtatta gtgcacggtt acagaataaa
    71041 aacaagaata ttcctattgc accagctcct cccaaccaaa aaccaaattg attcattgca
    71101 gcttgtggat atatccataa taaactaaat atatatgata aaattaaagc aaccactggt
    71161 gatagtgtaa ttacacattt ttctcctgca aagaagctta aaaatgctgg aactttaact
    71221 ttatatgttt tattgtaagt ccatgctata caagctccaa caattatccc accaaataca
    71281 cctgcattta atgtatcatt caataactct aaatttgact taaatatcat atatgcaact
    71341 acggctgcaa ccattacact tgtcttgtct ttagactttg agtaggcact agctgctcct
    71401 aataaaaata agtagtccac atttgaaaat actatattag atatattaga tatagctggc
    71461 acattgagca tatttggacc aaataataat cctaatatac ctgctgctgg cattacagct
    71521 attggcacca gcatagtctt tcctaaaagt gacagttgtt gcatcatttt gtttaagaat
    71581 ctcttcatat ccaatcccct ttctatttcg gtttaatttt ttgtgaaaac gatttattca
    71641 cattttatat tttaaatatt atatttgttt aaacaaattg tcaatatttt ttattcattt
    71701 tatttttatc atttagttta acatataaat ccttttaagt gtattgctat atctagtcta
    71761 tttttttaat tcattttttt tattttaaaa atatgtttaa ccatgtattt gaaacaaccc
    71821 acaaaataat tctattttgt cctttttatg gttgatatga ttctattttc actatacatg
    71881 tctaaacaca tttgatataa tttgttcata tcagttcaat aatattacta aagaccttta
    71941 aggagggata ggggtatatg gctaaaaata aattttcaga gatatatgaa gtattgaaag
    72001 aggaaatact tgatggtaaa tatacaagta atatgatgct gcctactgaa cttcaactta
    72061 ttgaaaggtt ttcatgtagc agaaacactg tacgtagagc aatttctcaa ttaaacacag
    72121 aaggatatgt tcaaagtata aaaggcaagg gtgttgtagt gttagaaaat agttgttcta
    72181 atgatttttt tctaaatatg cacaatttca aaggtgtaga atcgattgta gaagataaaa
    72241 aggttaatac tgctactagt gttctccact tcagcaaaat cttaattgat aataagttat
    72301 ctaaaaagac aggttttaaa gttggtagtg aagtatatta ccttcacaga ctaagatata
    72361 ttgataacat acctaaaatt ctcgacatta actattttct atgtagtata gttaaagacc
    72421 ttgatgtttc tatagcacaa ggctctattt ataaatatat agaagagtgt ctaggtacaa
    72481 aaattgtttc atcaagaaag atatttaaaa ttgaaaaagc tacagaactt gagttaaaaa
    72541 cgctacctct aaatgattat aattgtgttg gtgttattaa aaatagtgta tatactgatg
    72601 atggaaagct ttttgaatat actgaatcaa agcatacacc tgaaacattt gtattcatgg
    72661 atgttactca aagatattaa aaaaattatg tttaattaaa cataattttt ttacgtttag
    72721 acactttatc ccatactaac ctcactattc tatatacaat tatatgttta tacaaataat
    72781 tatttattgt atattttagc tttaatatta gtttaacgct tgacaatttg tttaaacata
    72841 ttataattaa cttataaatt acaggaggta tcaagtatga aaaattggtg gaaaaaagca
    72901 actgtctatc aaatatatcc aaaaagtttc aaagatagca acaatgatgg tataggtgat
    72961 ataaatggta ttatagaaaa attagattat ctgtattctt taggtgttga tttattatgg
    73021 ttgactccta tgtacgtttc tcctcaaaga gataatggat atgatataga agattattat
    73081 aatatagacc caaaatatgg gacaatgagt gactttgaaa aactcttaaa agaagctcat
    73141 aaaagagaca taaaaataat gatggatatg gtcctaaacc atacatctac tgaacataaa
    73201 tggtttaaag aatctaaaaa aagcaaagac aatccatatc gtgattatta tttctggaaa
    73261 gatgctaaac ctgatggttc tgttcctaat aactggatat ccagatttag tggaactgct
    73321 tggaaatatg atgaaaccac taaccaatat tatttacatt tatttgaaga aactcaagct
    73381 gatttaaatt gggaaaatga aaaggttcgt gaagaatgtt acaaaatact agaattttgg
    73441 gctgataaag gtattgatgg ttttcgttta gatgtagtca acctactctc caaaacacct
    73501 ggattacctg atgaccctat aacaggacca aaaggagatg gaagaactca ctacgctgat
    73561 ggtcctcgta tacacgaata tttacataat atgaatcaaa aagttttcaa acctaaaaat
    73621 atagttactg taggtgaaat gtcatctact acacctgaag agtgtatcaa ctatactaga
    73681 gaaaatcgag aagaactatc tatggttttt agcttccatc atatgaaaac agattataaa
    73741 ggaggcgcaa aatggactaa tgaaatgttc tctctggata aattaaaaaa agcacaatct
    73801 gactttcaat ataaaatgta tgaaggaaaa ggatggaatg ctctatttta ctctaatcac
    73861 gaccaaccta gagctttatc tagatttgga gatgatagat tttttcgtca agaaagtgct
    73921 aagatgttag ccataacatt atttggtcta cagggtacta catacatata tcaaggtgaa
    73981 gaaataggta tgacaaatgc ctactttact aaaatagatg aatatgatga tgctgaaagt
    74041 aagaatgcat actatcatat gattaaatct ggtattgatg aaaaggaggc attgcttata
    74101 cttcaacaaa aatccagaga taatgcccgt actcctatgc aatgggataa tactatttat
    74161 aaggggtttt ctaatcataa accgtggtta aaagttaata atgacaatat tagtgtagaa
    74221 aatgagctta atgattctcg ttcagtattt tatacttatc aaagattaat caaatatcgt
    74281 aaacaatatg atatttttac agaaggtact tatagattgt tagatgaaaa tcataaaaat
    74341 ctatttgttt atgaaagaga gtataaaaac caaaatcttc ttgttataag taattttact
    74401 catgataatg tagtatataa attacctgaa acttatttga ataaattaaa ctacacaata
    74461 cttgaaacca attacactag agatataatt gaaaataaaa tggaaataaa accttacgaa
    74521 agtataatga tatattataa ataaagttat ttatgtaaaa atcggtataa caccctggtg
    74581 ttataccaat tttactaaat tcaaagtaat atttatagaa tatctataga ttacaataat
    74641 tatttgactt ctacatcatt atatttcttt gaatatactt tagtcatata gaaatatata
    74701 ggaactacaa ttatcatccc acctaatccc caaactatct tcataggttc atcaatacct
    74761 gcttttatca gtaataatat acttataata actgcaaata ttggtataat tgctcctcca
    74821 ggtattctaa aatttacatc tttaccagca tacttctttc tcaatattag tacagctaaa
    74881 catgtaggaa tatattgaat aaatctagat acaacactta tttgagataa tgttgtgaat
    74941 gaacccgacc atgctattag taaagttcct atgacagata ctataattgc tatataagga
    75001 gctccatttt tattagtttt tcttatagac ttaggcatta atccttgttc aaccaaagca
    75061 gcagcagacc ttggtgtaaa tatggatgat gcaatattta tacctccaac agatactata
    75121 gttcctattg taattatata cccacctata ggacctaaca tcttaatggc agcatctgca
    75181 acaggagtag ctgaccctgc taagccatta cccaacaccc ctatacttat tcccagtata
    75241 agcatatata ttactgatac tacaaacatt accattacca atgctttagg tacatttttc
    75301 ttagggttct ccatatcttt tgctgcaaca gctaaagatt caaatcctgt aaaagcataa
    75361 aataaagtta tagatactgc tacaaaagct gatgacgcac tttgaccttt ttgtattatt
    75421 acaaatgggg taaaattaga accctttata aagaataatc ctacagctat aaataaaact
    75481 attggtaata attttcctat agtcatgata ttatttaagt gcttagattg tttcatcccc
    75541 ataaaattta taatcccaag tcctacaact aatataccaa ttattatatt tttagtaagt
    75601 ggttctgctg cttgtggcca tacagatgat agtgttacag caaagaaatt tgccatagta
    75661 gcccaagcaa tcatactaac tatccacttc ataaatccaa cttcaaatcc aacaaaatct
    75721 ccaaatgcct cttttgcata aagatagggc cctccatcag tatcaaacca actacctgct
    75781 tcagcaaaac ataaagcaat agaaacagct aaaagcatac aaaaaactaa tactaatata
    75841 cttgctggac ctatatctgt ataagcatca ccaggtaacc cgaatatacc tgaccctatt
    75901 attgcattga ttcctaatag tacaatactc caaaaaccta acttaatgcc tttttccatt
    75961 gttattcccc ccaaagccaa cttaatatat ttgtattttt tatttagatg cttctttaac
    76021 tattgccata aatatttttt tcatattatc ataatcccta gtcatcattt ctggatgcca
    76081 ttgtatccct attacaaact cacttccttc cttttctata gcttcaatta aaccgtcttt
    76141 agatgtagct gaaacaatat atcccggtgc tactttgttg acaactaagt gatgaaaact
    76201 attaactaaa acttcttttt ctcctaatat ttcatataat tttgtcccct cctttatctg
    76261 tactgtatgt gtaggtacat tagatagatg ttgctgattg tgtttaatat aagcaccttc
    76321 aattaaagat aaatcttgat acaaactacc tccttcagtt acatttataa tttgttctcc
    76381 tctacatata cctaaaactg gttttttcat atctaaagca tgttttaata atttcatatc
    76441 aaaactatct ctctttggtg atattgcccc caacttatta tgaggttctt ctttccatat
    76501 gagtggattt acatcttgtc ccccagatag tataagcgca tctatattag atacctgctc
    76561 ctttataatc tcatcatcat atacaatcgg tacaatatat ggtatagctt tacacataac
    76621 tactgattgt atataatcat tatttacata agccctttca tagccaggaa acattcctcc
    76681 ttcatcaatt agtaaattac ctgatattcc tattattgga tatttctttt tagccaattt
    76741 cttcacccct taacttattt gtgaacaata aaaaatgcta cttctcttaa agagcaagta
    76801 gcataccaag attttattta tttgaacatt ataatttatt ttagaaatac tttttttgaa
    76861 tacgagtaat ataaataact ttatttactt atattttatt ttaatcctgt ttagtttgac
    76921 ttttttaaat tgttttaagt acaactaata ggtaaaatag gcatttagat tttccttttt
    76981 atcaacctat taaatactgt ttaatatatt ttttcccctt ctatttaatt cacttccctt
    77041 tctaccagat tcacatatta tcaaatccag ctcttttaac atattaagta ttccccttac
    77101 ctcaccttct gttatattgt agcctaattc atttattgaa ttaacaatac catttctacc
    77161 tatattttta ttaagattat tggcattttt taaacactcc attactaact ttactttctc
    77221 tatagatgtt ctatccttta atatacttat ttctttacta aaatcttcag ttatatttaa
    77281 taagttatga ggtaaatcat ttattaaaat aacatcctca gaactcataa tgttaatata
    77341 catagcagta ttttttaatt ctcttatatt acctggccat tcatatgcat taataatgtc
    77401 ttgaacatct tgactaattg ctctcttcct tttcataaaa tgctttaaca taacttctat
    77461 atcttctttt cgctctctta aaggtggtat atttatgggc aatacattta tcctatagta
    77521 taaatctgct ctaaatctat ctccttttat catttctaat aaatttttat ttgtagccgc
    77581 aattactcta acatctatat ctattacatt ttctcctcca accctcatta cttgattctc
    77641 ttgtaatact ctaagtaatt tgctttgtaa gtatataggc atgtctccta tttcatccaa
    77701 aaatatagtt ccattgttag cctgttcaaa taatcctttt ttacctcctt ttaaagctcc
    77761 tgtaaaagca ccttcttcat atccaaaaag ttcactttca agtaaatttt ctggcatagc
    77821 tgcacagttt atcgctataa atggctgact atgtcttggt gatgcattat gaatagactg
    77881 agccatgagt tcttttcccg ttccactttc tcccgttata agaattgtat aatcagattc
    77941 agctattttc atacctaatt tcttagttct ttccatcttc gttgaaactg tttttatatc
    78001 atcaaaagta tatctagcaa cttgtccctt ttctctaagc ttctttgata ggttttgctc
    78061 caattttctt atgtaagtta tttcttgaat acaaaaataa tatccagtaa cccttccaaa
    78121 actctctata ttatacttat ttacgtttaa gtacttatta ttaaatttta taacttcatc
    78181 atgtgcctta ctcaaactaa aaatcttttt aatattctca ttctctaatt catctatatt
    78241 tttccctata atattacttt gaatatctag tatatcccct aaactattat tgcaaataat
    78301 tatgtttccc ttatctgata ccattgccat acctaagttt gataaattta ttatagaatt
    78361 taattcatct gcttttatag taagttcttt atatttagta tttattcctg aatataaact
    78421 aattatttca tctgtatact taattagcct ttcagtaatt tctttatcat ccagtttgag
    78481 ttttgctatt atttgaataa acgttgaact atcaatatac ctatggccta aatcaataac
    78541 ttcttctata tattttggaa ctaaacttgc ctctcctggc gttatagcta tcttaatatt
    78601 tctatattct tcattgggat tgtatggtat aaaattcaga tgatttattc ctatattgta
    78661 taaattagat attgtttcca atacagtatg cttattatcg tttactacta atacatctat
    78721 tccttctggc aatgaaaata acttatatat atccttttgc tttatgctcc tatttatagt
    78781 tattatcttt gagacatctt ctacatattt ttttattttt aatactctat catctatcat
    78841 taccaatatt atgtcatctt ttattaattc cttctctgtt attttattta aataataatt
    78901 ttttatcatt actttatctt taaatatcat ttctagattt ttatttaaga aacattctaa
    78961 tttagacaac ccatcagtta ctactgctat tgttttcatt tgattactcc ttttaaaata
    79021 tactctactc ttttataata tacatctgat tttcacttta acagcacaaa aaattgtaca
    79081 tttagtatac taacatattc ctttattagt tttatgtccc taaatatcat agttgcaata
    79141 tctatcatat ttcttaaact tctataaagc aaaaattgtg ccaaattaat aattttctta
    79201 attttattct aaagttcctc aatagtattt acagacttag cacttatagc ttataagtct
    79261 ttatattatt aatctatttt tataggttaa ttgtacaaat catatatcac ttttacccat
    79321 taaatgcatt ataaaaaaga tggaataacg attcgtcact ccaccttttt tgtaataaaa
    79381 aattgtatat ataaacacta tttactactc ttctaagtac aaacattatc tacatactat
    79441 aacctttcac cattagattc tattacttgt ttataccagt caaaactctt tttcttaatc
    79501 ctagacaagt ctccacttcc atcatcatac ttatccacgt atataaaccc atatctcttg
    79561 gccatctcac cagtagatgc acttactaaa tctatacatc cccacggagt atatccaaat
    79621 aaatcaacac catcttctac agcttccttc atttgctcta tatgtgcttt taaatactct
    79681 atacgatagt catcatttat cactccatta gattcttttt tatcataagc tcctaaacca
    79741 ttttcaacta ccatcatagg tattctatat ctatcataaa tttcatttag tgcatatcta
    79801 agcccttcag ggtctatttg ccatccccat tcactagact taagatatgg atttttcact
    79861 ccacctaata tgttgccact tgtattatct tctttagaat cactacttac acatgtagac
    79921 atataataac taaatgtata aaaatctaca caaccttctt ttaaaatttc taaatctcct
    79981 ttttccattt ttatttcaat attattttct ccaaaatatc tattcatata agttggatat
    80041 tcgccacgca cttgtacatc tccacagaaa taattcatta ctctactatc tctttgagtt
    80101 ttaactgcat catctggatt acaagtataa ggatacattg ttgcaaatat ttgcatacat
    80161 ccaacttgat aatttgaatc tatttcatga gctaacttaa cagccttagc acttgctaca
    80221 aattgatgat gtaacccttg aaaacgaagt tgaggtatat ctacttggtt tataaaatct
    80281 gtagtccctt catttaatat tccttgtgat aagtagcctc ccataggcat tgtagctgaa
    80341 tttatttcat taaatgtcag ccaatatttt acttttcctt tatatctttt aaatattgtt
    80401 tcacagtaat tcatatacaa gtctattaca tctcttgaaa cccatccatt gtatttctct
    80461 gttattgcaa atggtatttc atagtgagat attgttatta atggttctat attatatttt
    80521 aaacattcat ctatcacatt ttcataaaat ttaagtcctg cttcatttgg ttctttctcc
    80581 attccagttg gaaatattct agtccatgct attgaaaatc taaatacctt aaatcccatt
    80641 tctgcaaata aagctatatc ttctttgtat ctgtgataaa aatctattgc ttcatgactt
    80701 ggataaaatg ttcctttttc tataactctc gttattcttt tacttacttt ttgagaacct
    80761 ccagtacaca tatctgaaca agaaggacct ttcccatcta aattccatgc tccttcacat
    80821 tgatttgctg ctgttgctcc accccataaa aaatcttttc taagtgccat aattctacct
    80881 ccaataattt atttatagta actttatttt aaaataaaaa tacatatata taattcttaa
    80941 ttaatagaac tctcttttac gctaaaacag ttatcaattc ctgactatta tttacatgct
    81001 tttgtgtatt ttctaaaata tccacataat cagaataatt agtaacaact actggtgttt
    81061 ctaagcaata tccttctttt gaaatacttt ctatgtcaaa agttattaat atctgacctt
    81121 ttttaatctt atccccttga ttaacaaaag atttgaaata tttaccttcc aactgaatag
    81181 tatttaaccc tatatgtatc aatagttcac aaccattatc agatataatt cctattgcat
    81241 gttttgttgg aaataaagtc attacagtcc catcaaatgg tgccactact tttccttctt
    81301 taggtgttat tgctacacct tttcccaata tacctgttga aaacgctgca tcttgtatct
    81361 gctccaaagc ctttacttca ccttttattg ggctatatac tacttctctt ttgttttttt
    81421 ctataacgcc ttgcccatta tcatctttag aaatttctac tatagcatca tctttccaaa
    81481 aaaataatgt taaaacaaat cctactacaa tagctactat tattgctatt atagttgcat
    81541 aaacaccttt catatctcca gttgttggat ttatataatt aggtatacca aatattccaa
    81601 gtccacccat tacataactt tttacattca ttatccccat tacagctcct gccacaccac
    81661 cacctacaca gctatatatg aatggtgttt ttcttggtaa agttattcca tatattgcag
    81721 gctctgttac accacatatc cctgaaataa ctgcaggtat acacagctct tttatcttct
    81781 tatcttttaa tttaaagtac attgctgcta ctactgctgt ttgtgcaaaa gatggtacaa
    81841 atgctcccac taatattgtg tcaaacccca tagtcataag gtttgacata gctattggta
    81901 ctaatcccca atgtagacca aatattacaa gcacttgcca caataaacca gttaatgcac
    81961 cacataaaat tggtgaaaag ttaaataaag ctaaaaatcc atttccaact atattagaag
    82021 cataggtagc tataggccct ataaccataa atcccaatgg taaagaaact aataaaactg
    82081 ccattggtac aaagaaattc tttactacat ctggtattat tttagcaaac actttctcca
    82141 acttagctgc taataatact attaaaatta ctggtactac tgttgaagtg tagttcattg
    82201 ctattactgg taatcctaag aaagttatat atactggtga ttcaaatatt gttccagtaa
    82261 atagattgta taaaggttga cctgtagatg ctagagtatc taattgaata cctgaatagc
    82321 ataaaactgc acctataagc attccaataa atggttttaa tttgaatttc ttagcagctg
    82381 tatatccaag aattattggc atatactgga acattgcatc tccaattgca tttaacataa
    82441 tatatgcacc atcagtttct ccatacaaac ccaatgctgt aaatactgca ttaaatcctt
    82501 ttatcatacc agcagcacac agaactccta atattggttg aaaaactcct gatattatgt
    82561 ctataaactt attaagtaat ccttttggcg catctgagtc tgaattatct attgtatctc
    82621 ctcctaatcc agccaaatcg cacacaactt cataaacatc tggaacatga ttaccaataa
    82681 ctacttggta ttgacctgca cttttcatta cagtaactat accatccatt ttttttagca
    82741 catcatcatt tgctattgac tcatctttta atttaaaacg tagcctcgtt atacagtgag
    82801 ataaactgct aatattatcc tttcctccta cattcgcaat gatttctttt gatagttgtt
    82861 catactttct cattttttct cctccatttt ctttttgaaa tatgaaggtt tggccaactt
    82921 aatgtcacca cccaatatat ataaacctaa ttattaggat ttatatctga cttaatactt
    82981 ttacttacca ctctttcaac gtgaatagtt aagtataatt tttcctcatc tgttaaatcg
    83041 tagttgtatt ttttatgtat aaattcatcc aacttttcta tgaatttata agcattttta
    83101 tatttaactt ttattacatt taataaatca tcttcattat tttcatgtaa attattacta
    83161 acaattcgtt ctgcaaaata ctttaagtga gtaataaatc tatgataata aactgaatct
    83221 tcatcaaata ctattctgta atggtattta accatatttg aaatttcttg tattatttgt
    83281 gtaatctcat atatagtttt tatactttga tccatttgtg cattaactat atgcagtgct
    83341 ataaatccag cttcatcttc tgatagtcta atttcaaatt ttttttctat ataatccaat
    83401 gcctctaacc ctattttaaa ttcactctta taaaatcttt ttatatccca aagtaataca
    83461 ttttttacac ttactccttc acgagctctt tctattgcag tatacatatg gtctgttaaa
    83521 gaaatataaa tactatcatt taatcttttc cctagttttt ctttagcata taaaattatt
    83581 tcatctgata attccatata tcttatagga atatctgcta ttagttcttt aaatttatca
    83641 gatatatttg ggtctgaaag tttgaatatc ttatcaattt tatcctttga tatatgctct
    83701 cctgtacgtt ttttataagc taaacctctc cccataacta ctatttcctt atgattttca
    83761 tcagttgtaa taattacatt attattgagt attttttcaa taatcattgt gatgccccct
    83821 ttattagcat taagttaaaa taaatctttt ttaattattt agaatattta aaatgtaatt
    83881 tattacataa aaaaaaacct atttattaca cattaaatag actcccatga gtcctgagta
    83941 ataaataggt ttagcttgta tttaaacaat cactatccgt ttgtatttta ttttaattat
    84001 tatttattat atgttagcaa atttattttt tagtgtcaac tttttctcaa tattttaatt
    84061 ttaaataaat tatataaatt gaatcttcaa agtactattt ttatcaataa acaaaataaa
    84121 aaaggtatta ctttctttaa gtaataccca tttattttta atttaagtgg tttttcttaa
    84181 tctcatcaag tagtccatct tctaaataaa tttctaatgc acatcctacc attgccttta
    84241 ctgctttgtg aagtttatca taagcttcct cagaatttgc ataatttaga aattcttttt
    84301 catgaacata taccattgga cttatatcta aggctatttc tgtatacata gtagggcaaa
    84361 cttgacttac attacctata tctgtagaac ctactggacc atctttacct tctaatatat
    84421 ctgttatacc tgcctcaatc aaattattct ttgttatctt ttgaagtact ttgttattta
    84481 ttatgttgtc aaaagaattt tcaaagtatc tataagaaag cttagctcct gtcattaact
    84541 ctgcaccttt tgcacagttt ataacttttt tagttacttc atctaaataa cttctttcag
    84601 cagctcttac gaaaaactta caagctgctt tttctggaac tatatttgga gcctctcctc
    84661 catttgaaac tataccatgt attctaacat ctgattttac atgttgtctt agtgcattta
    84721 tcccagcaaa agtaagttgt actgcatcta gtgcattgac tcccatatga gggtgactag
    84781 ctgcatgtgc tgatacccct tcaaaactaa actctaatga atctatcgcc aaagccttac
    84841 agtttatatt attaaaagct tctatatgca tttgataact tacatcaaca tcatcaaaag
    84901 ctcctgcctt aactaaatca cattttcctc ctgttgtttc ttcagctggt gttcctatta
    84961 gtacaatttt tcctttaaaa ttttctttta acttacttaa tactatacaa gctcctagtg
    85021 tagatgctgc aatccagtta tgtccacaag catgagctgg ttctttattt tctccatatc
    85081 caggaagtgc atcatactca gctaaaaatg ctatggtagg tccatcatta tctcctaatt
    85141 cagctctaaa agcagtctcc atattacaat atggataaac tgtatcaaat ccatattcct
    85201 tcattttttc tactaagtat tttgatgata tgtattcttc ttcccctaat tcaggattgt
    85261 taaatataaa attacaaact tcttcaattt cttttccaag ttcattctct atctcataag
    85321 ctctcttctt tatactctct atcataattt acctcctact agaatcctag atataatcct
    85381 attgtcaaaa atgccattac aagaattgtt aatactacca ttaaaggaat tacgaatcta
    85441 acccactttg accaaggaat attggctact gctagtgctc ccattaaaac acctgatgta
    85501 ggtgttatca agttagttac acctatacca aattgataag ctgtaactat catttgtctt
    85561 gatacatcta ctaagtcgcc aagtggtgca agtacaggta ttgtaagtga tgcaagccct
    85621 gatgctgatg gtattaaaaa tgctattaat ccttctatta agaaagttaa atttataaat
    85681 atagtttttg gtaatccatt taataaattt gctgcagaat ttaaaattgt atctattata
    85741 aatccatttt ctgctattat tacgattcca cgtgcaaatg ctatacacaa tcctgctgta
    85801 attaaatctc ctgctccact tataaatgaa ttaactatct catcttgttt aagccctgat
    85861 gctattcctg atattatacc tatagctgta aatatcattg caatttcagt tatgtaccat
    85921 tctagtctta aaactccata tatcataatc gccataccta ttgtgaaaat ggctattacc
    85981 atggcttctc tttttgtaaa ttcctttata tttgtatcac tattaaccat taattcttga
    86041 tttagtgata tatcatgtac taaagatttt ttagggtctt ttttaacttt attggcatac
    86101 atcataacaa atcctataga tatagccata tatattataa acataacaac tctaaactct
    86161 attccagaac ctggtactat ttgtgataat gcttgtgcta ttcctacaga gaaaggattc
    86221 gtagtagctg ctccaaatcc agctgttgct cctataaata ctgtggccac tgctgtcaat
    86281 gaatcatatc ccatactggt cataagtgga ataaatatca tataaaaagg tagtgtctct
    86341 tcactcattc caaacgtcgt cccacctagt ccaaatagaa tcattgaaat cggtattatt
    86401 aaaaattgaa acttcttcat tttatttaca gtatgagcta taacagcttc tatagctcct
    86461 gttttattaa ctatcccaaa agctcctcca actattaaaa caaatccaac tacttcagct
    86521 gcatctataa acccgtttat aggtgctgta aatacatcag taattccttg tggatttgat
    86581 ggtgcttttt cataagttcc agctacaaca actgaccttc cgtctatatc tactctttca
    86641 aaatttccac ttggcactat ccaagtaaga attgccatta acactattag caaaaatatt
    86701 attgtaagtg tctgtggcat agtaaacttt ttctttttta aactgctcat ttttaatctc
    86761 cccacttttt aaattaaata ttttattatt gcatcccttt atcctatttt gtatagatgt
    86821 aaaaaagctc aacatggata catgttgagc taaatgtgct aaatacaaca tacctgcatc
    86881 ttccctttat cttgtttaag atagctctcc atcaaaattc gggataattt tgatgacagt
    86941 actgtaccta ttaaatacag tcccagcact agcttcggac actagcactt cggcacttac
    87001 tccttttata ttgcctcatt ggtttccaac ctcttcaata ttaatcttag taaatgcaac
    87061 ctctacctca atctgtttgt tagatgaggt aattcttatt aatttttatt aattcaaagt
    87121 aattgtagca taatatgtcg agattgtaaa tattttcagt ataataattc ttactttatg
    87181 atttcattcc atttttcaca aataattttt tctccatata atttaaatac tgtagtatat
    87241 tttaaataca cacaaacttt ccacaaattt taaattatta taataccttt ataataaaaa
    87301 ataaaagcta tgtaaactta tcaatttaca cagctttata tacattaatc tactccaagt
    87361 acagctttaa gctttgatgc tattgtaata actcgtggac caaatataac ttgaactgag
    87421 tttttctttt taacaactcc acttgcaccc aattcattta cccagaagcc atcttcatag
    87481 aatccatcaa ttgaatttag ctctacccta agtctagttg cacagtttgt aacatttttt
    87541 atattattac ttcctcctaa accttctatt atagaatgta caagctttgt atctttatca
    87601 tctacttcct cttctactgc attgttgtat gctgttttac cagcatctac agattgtctt
    87661 tctctatatt ctttcttact ataaagctta acttcttctg aacttcttcc tggtgttttt
    87721 atatcaaact tcttgattgc ccatgtaaat attatataag taactataaa aaatattggt
    87781 atcaaaaata ataatggtaa cgcatccact ttttgtggtt gtaataaatt aggaaacata
    87841 tttctaaatg attctcccat tatagaaaca ttaaacattt ctgtaaatac atacgtcaat
    87901 cctgccagtg gtacatatgc tacaaaatac aataatggtg caacaaatag gaatgtatac
    87961 tctattggtt ccgttacccc taccaacatg gctgttacta ttgctggtat caatatactt
    88021 attgcttttt tcttattagc attatcagcc aacttataca tagctaaagc tgctgctggt
    88081 aatattgcaa aatgtattaa taaacgacct gttgtgaagt tacgagttat ataagatagt
    88141 gtatctgggt ctcccatttg agctaatctt atattattaa caccctcgta aattgctcca
    88201 cctacttcca ttgttccacc tactcttgta tattctatag ggaatgcaat taagtgatgt
    88261 ataccaaatg gtaataatgc tttatccatt gctccaaaag taaatgttcc taataatcca
    88321 ctagaaccta tccaattacc aagtttagat aatgccaacc ctactggtgg ccatataaag
    88381 tacattgctg tacccaatac tattgatgct ataaacatca taatcattga aaatcttgga
    88441 cctgagaaaa aagataatgc actaggaagt tctatgtcaa caaatttgtt atgtactgca
    88501 ctagctacaa atccagctat tatagctcca aatatactac aatcatatga aaagattcct
    88561 aagaaagaac catataaaga acttcgacta tatgcttctg cctctcctaa tccagatgcc
    88621 ataaacgctt ctgctgtaac tgtatctgaa tttataccat ttgctgctaa caatgtactt
    88681 ataactgtgt gcattcctat aaataaaaca attcctccta atgcacccca tcctttttcc
    88741 tttttagata atccaaaggc tatacctgta acaaagaata ttggtaagta tctcattacc
    88801 ataaatccta aatcgtttat tactttaaag aatacattta taaatgaccc ttcttttatt
    88861 agtccgctaa gccctaatgc agaaacgttt tccatatttg caaaagctga ccctaatcct
    88921 ataaatactc ctgctacaac aagtaatata acaggtatca tcattgctcc agaaagtact
    88981 tgtaatttat ccttcatagt attatttcct ccatttttat tgaaatgcca ggctatataa
    89041 tgcatatata tatacttcta ttgctttgta taatgtatct atacttatat tttcatttgc
    89101 ctgatgtgaa tttggattat ccccctctat tgtgggtcca aatgcaactc cattttttaa
    89161 cactcttgca taagatgcag ctccttttgt aaaaagttcg gcttcttttc caaaaccttg
    89221 tttatatgca tttgataatt tatttattaa ttcactatct ggttttacat acagtaattt
    89281 taaatcctta tatatatcaa ctattaaatt ttcttttttt ccaatttcat taattctatt
    89341 agttataaac tcccaactta tacccttagg atatctaaag tctattttca tattcaattc
    89401 atttttctct aagaagatac tcattataca tattgtagaa actcccatat ctacatcttc
    89461 tttatacatc cctaattttt ttccatgatt atcatctgta aagtatgaat ttaaaatatc
    89521 ccttattata acgcctttat catttagttt tttaattttc tctaaatctt ttgctaaact
    89581 aaatgcacag ttatatgacc tgtgtggatt tctcgataaa gccctttctc ctgtatatct
    89641 tactaatact ttaccttcat ctaattcttc tatctctgta taataagcta atgattctac
    89701 taaatctttc ttatcattag ttttaaaaac agcctcaatt ttgtcacata caaatccatc
    89761 ttctttgttt gactttatat caactaaatt gtgatttcta aatttatctt tatctatttt
    89821 ctttcttaga ttgaagtata aaataccttt ttctccattt actattggga agtttccatc
    89881 tggagaaaat gcaaattttg gctgttcatt gacactaaag taatgctcca tacattccca
    89941 agtcgtctct tcagctccac ccactatcaa tctaatcttt ctcttcggct tttcattaag
    90001 ttctcttaag aaaagtaatg catataaaat ccctatcaaa ggtcctttgt tgtcattaac
    90061 tcctctacca taaagatagt tatctttttg acatacttta aaaggtttac tcttccaaag
    90121 ttctttatta tatattggca ccacatctat atgattaagc acccctacta cttcttctcc
    90181 ttctccatat tctatatgaa ttgcatatcc atcaaagtct tttacaacaa aatctttgtc
    90241 ttttgctatt tgaataagct tatcgaaggc atttcttatt tctatcccaa atggttgatt
    90301 tatatctgtt gtactttcat ctctaattga aggtatttca actaaacttc taatatcatt
    90361 tatgatattt tcttgattgg attttaaata atcaataatt agttctttgt ttactatcat
    90421 cttaattatt tatcacccct ttatattaat tttacaaagc atttcagttc atatctacat
    90481 tataaatttt gaatattatt ttttcaatat ttcaaatact tctctaagtt accataatga
    90541 tacggtaaac aatcaacaga ttatgacaaa atcatactat acctattact aatattttaa
    90601 cttatctatt acgtcttttt taatgtaagt ttattccaaa aatacataaa aaaagatgta
    90661 gccttagcta catcttctta tatctattca acttccatta ttatgctatt aatatctaca
    90721 tttccaggtt ctatcctatc ttttactgtt ctcttaacag aatcagcatc atccattata
    90781 actacaggag ttattatatt taaatcattt gacgttataa aatctaaatc tacttccatt
    90841 attaaatctt tagcttttac cttatctcct gcctttacct taacatcaaa cggctttcct
    90901 tctagtgaca ttgtctctaa acctacatgt attaatatat ttgtattatc attactctta
    90961 atcattattg catgctttgt atcaaataca ttgactattt caccatcaac aggagaatat
    91021 aacttacctt cacttggtat tattgctact ccatctccca tcatcttttg ggcaaaaact
    91081 gcatctggaa catcttctaa gttcactaaa tttcccttaa aagggctata tattttctca
    91141 atcttatttt cttttttctt aaatatatta aacataacac actctccaca ttataaaatt
    91201 ttatgataat atttttctta aagcttttgc tacaccatca tttacattag tatcagttac
    91261 aaaatctgcc atagatttta cttcatctgt agcatttccc atagcaatac caagacctgc
    91321 aaatttaatc atggatatat cattttcatt atcacctata caaataactt ctttgctatc
    91381 tatacctaat atatcacaaa attttttaac tgcaatacct tttgaagtac ctttactcat
    91441 aacttcaaag tttatctttc cagaacttac tacttctaaa tcttcttgtt ttttaaattc
    91501 ttcctttgct tctctcaaag aatctacgtt ttctgagaaa agtatacatt ttaaaatttc
    91561 attatcagct ttttctaata aagtttcaca acttgcattt tctattattt caattctgtc
    91621 ttcttcttta tttttactat ttattaatct atatggatgt tcttcaccta tttcattgtt
    91681 ggatataact attttacagc ctttaaaatg tttgtttaaa ttatactttt cacctattgt
    91741 atagattttc tttagagctt ctttgctcaa aaccttctta tactcatatc ccagtaattt
    91801 aaaatatgtc ccattagttg atataatata tatatcatcc cctaaaacac ttgtaaaata
    91861 tttcatagca ttataaggtc ttcccgtaac taaggctacc ttgataccct tttccatggc
    91921 ttcttttagt gctttaatat tttcttctga tacttcaaat cctttaccca tcaaagtacc
    91981 atccatatca gtacaaatta atttatatcg catttgtatc acatcctagt aagatttttc
    92041 taatatttca acaaggtctt ctttctttcc aaaaggtaaa aatcctaaaa ctggacagct
    92101 tgttatttgt tctaattgtt cctttgttac attaaactca gacatttttg tcttaagccc
    92161 cactctcttt aaaaaacttt ctatttcatt tcctaaagtt ttagctgctt catcatcttc
    92221 cactttttct aattcttggt ttagtattct cgctactttg gcaaatttct ctatattatc
    92281 cttatagaac ttttctgcaa attttgggaa cactatagcc aaagcctcac catgaggaat
    92341 atgtgtaact cctcctatta tttcacttag tggatgtggt gctgctgctc cagcatttgc
    92401 cagtgaactt cctcctaatg tatctgctac tgctaacttt gttctgtatt ctatattatt
    92461 tttatcttcc attactttag gtagatagtt aatgactaat tccatagatt tttcagacat
    92521 tatctctgta aaatcattag catttggatt tatataactt tcaaatgcat gagtaaaagc
    92581 atcaaatgct gttgatgcag taattctctc tggcagagtt aacataagct ctgggtcaac
    92641 tatacattct tttgagaaac aattttgatg aaatattgta tttttctcgc ttcctctcga
    92701 tattactgct gcttgtgtaa cttggcttcc tgttccagaa gtagttgata cagctattaa
    92761 tggtaattct ttttcactta ccttatcgta tattttaaat ggatttgtat atgtactaaa
    92821 catataatcc caatctattt tttctaaacc aaaagtcaat gctaatactt ttgcagtatc
    92881 tatacttgaa cctcctccaa cagctaaaac aacgtctaca gattcttttt tagctaattc
    92941 aaacccttcg tttattaatt ctacagttgg gtttggctct actctctgaa cctcccatga
    93001 ctaaagtcac agggttcctg cttcacagaa ttttgcatac taaaatatgt cttactaatt
    93061 ctccacaggc catccccgta gttcctacgg ttcttacata agttatttat tttgaattgt
    93121 tattagtctt aatccttctt ttaatatatt tatacttgca tttatatctc tatcgtgagt
    93181 ttcattacaa ctaggacaaa tccattctct tatatttaag tccttcactt cctcgttttt
    93241 atacccacat ttattgcata tttgtgaact tgcaaagaat ttacctacct ttacaatttg
    93301 tctaccatgc caattagcct tgtattctaa ttgacgaata aattctgacc atgatacatc
    93361 tgaaattgag cgagatagtt tacgattttt aatcatattc tttacttgta aatcttctat
    93421 gcaaataata tcattctctt ttattaattt agtagataat ttttg
//
LOCUS       DAMJWC010000006        90632 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMJWC010000006 DAMJWC010000000
VERSION     DAMJWC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 90632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.006"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(72..845)
                     /locus_tag="PC503_000532"
     CDS             complement(72..845)
                     /locus_tag="PC503_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF2526551.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(845..1231)
                     /locus_tag="PC503_000533"
     CDS             complement(845..1231)
                     /locus_tag="PC503_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2526552.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1256..1573)
                     /locus_tag="PC503_000534"
     CDS             complement(1256..1573)
                     /locus_tag="PC503_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF2526553.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1585..1845)
                     /locus_tag="PC503_000535"
     CDS             complement(1585..1845)
                     /locus_tag="PC503_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF2526554.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1845..2141)
                     /locus_tag="PC503_000536"
     CDS             complement(1845..2141)
                     /locus_tag="PC503_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2526555.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="PC503_000537"
     CDS             complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="PC503_000537"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF2526556.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="PC503_000538"
     CDS             complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="PC503_000538"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF2526557.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6558..7673)
                     /gene="recF"
                     /locus_tag="PC503_000539"
     CDS             complement(6558..7673)
                     /gene="recF"
                     /locus_tag="PC503_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF2526558.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="PC503_000540"
     CDS             complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="PC503_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF2526559.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8034..9140)
                     /locus_tag="PC503_000541"
     CDS             complement(8034..9140)
                     /locus_tag="PC503_000541"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF2526560.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="PC503_000542"
     CDS             complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="PC503_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF2526561.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11360..11497
                     /gene="rpmH"
                     /locus_tag="PC503_000543"
     CDS             11360..11497
                     /gene="rpmH"
                     /locus_tag="PC503_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF2526562.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11575..11919
                     /gene="rnpA"
                     /locus_tag="PC503_000544"
     CDS             11575..11919
                     /gene="rnpA"
                     /locus_tag="PC503_000544"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF2526563.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11951..12202
                     /gene="yidD"
                     /locus_tag="PC503_000545"
     CDS             11951..12202
                     /gene="yidD"
                     /locus_tag="PC503_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF2526564.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12234..12941
                     /locus_tag="PC503_000546"
     CDS             12234..12941
                     /locus_tag="PC503_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2526565.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12910..13539
                     /locus_tag="PC503_000547"
     CDS             12910..13539
                     /locus_tag="PC503_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF2526566.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13651..15030
                     /gene="mnmE"
                     /locus_tag="PC503_000548"
     CDS             13651..15030
                     /gene="mnmE"
                     /locus_tag="PC503_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF2526567.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15128..17020
                     /gene="mnmG"
                     /locus_tag="PC503_000549"
     CDS             15128..17020
                     /gene="mnmG"
                     /locus_tag="PC503_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF2526568.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17013..17732
                     /gene="rsmG"
                     /locus_tag="PC503_000550"
     CDS             17013..17732
                     /gene="rsmG"
                     /locus_tag="PC503_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF2526569.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKDEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17895..18680
                     /gene="noc"
                     /locus_tag="PC503_000551"
     CDS             17895..18680
                     /gene="noc"
                     /locus_tag="PC503_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF2526570.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18815..19588
                     /locus_tag="PC503_000552"
     CDS             18815..19588
                     /locus_tag="PC503_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2526571.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19590..20453
                     /locus_tag="PC503_000553"
     CDS             19590..20453
                     /locus_tag="PC503_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2526572.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20486..21628
                     /locus_tag="PC503_000554"
     CDS             20486..21628
                     /locus_tag="PC503_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2526573.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21762..22337)
                     /locus_tag="PC503_000555"
     CDS             complement(21762..22337)
                     /locus_tag="PC503_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF2526574.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22597..23889
                     /locus_tag="PC503_000556"
     CDS             22597..23889
                     /locus_tag="PC503_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2526575.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            23994..24596
                     /gene="yedF"
                     /locus_tag="PC503_000557"
     CDS             23994..24596
                     /gene="yedF"
                     /locus_tag="PC503_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF2526576.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24669..24932
                     /locus_tag="PC503_000558"
     CDS             24669..24932
                     /locus_tag="PC503_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF2526577.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24947..25132
                     /locus_tag="PC503_000559"
     CDS             24947..25132
                     /locus_tag="PC503_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF2526578.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25235..26431
                     /locus_tag="PC503_000560"
     CDS             25235..26431
                     /locus_tag="PC503_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2526579.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26645..26923
                     /locus_tag="PC503_000561"
     CDS             26645..26923
                     /locus_tag="PC503_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF2526580.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26960..27394
                     /gene="ssb"
                     /locus_tag="PC503_000562"
     CDS             26960..27394
                     /gene="ssb"
                     /locus_tag="PC503_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2526581.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27413..27640
                     /locus_tag="PC503_000563"
     CDS             27413..27640
                     /locus_tag="PC503_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF2526582.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27783..28103
                     /locus_tag="PC503_000564"
     CDS             27783..28103
                     /locus_tag="PC503_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2526583.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28111..29067
                     /locus_tag="PC503_000565"
     CDS             28111..29067
                     /locus_tag="PC503_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF2526584.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29078..31072
                     /locus_tag="PC503_000566"
     CDS             29078..31072
                     /locus_tag="PC503_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF2526585.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31073..31522
                     /locus_tag="PC503_000567"
     CDS             31073..31522
                     /locus_tag="PC503_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF2526586.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31541..32869
                     /gene="dnaB"
                     /locus_tag="PC503_000568"
     CDS             31541..32869
                     /gene="dnaB"
                     /locus_tag="PC503_000568"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF2526587.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33074..33382
                     /locus_tag="PC503_000569"
     CDS             33074..33382
                     /locus_tag="PC503_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526588.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33464..34753
                     /locus_tag="PC503_000570"
     CDS             33464..34753
                     /locus_tag="PC503_000570"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF2526589.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35079..35154
                     /locus_tag="PC503_000571"
     tRNA            35079..35154
                     /locus_tag="PC503_000571"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35112..35114,aa:Lys,seq:ttt)
     gene            35161..35235
                     /locus_tag="PC503_000572"
     tRNA            35161..35235
                     /locus_tag="PC503_000572"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35194..35196,aa:Glu,seq:ttc)
     gene            35240..35315
                     /locus_tag="PC503_000573"
     tRNA            35240..35315
                     /locus_tag="PC503_000573"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35273..35275,aa:Val,seq:tac)
     gene            35349..35423
                     /locus_tag="PC503_000574"
     tRNA            35349..35423
                     /locus_tag="PC503_000574"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35381..35383,aa:Thr,seq:tgt)
     gene            complement(35806..36798)
                     /locus_tag="PC503_000575"
     CDS             complement(35806..36798)
                     /locus_tag="PC503_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2526590.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36807..37865)
                     /locus_tag="PC503_000576"
     CDS             complement(36807..37865)
                     /locus_tag="PC503_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2526591.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            37990..39453
                     /locus_tag="PC503_000577"
     CDS             37990..39453
                     /locus_tag="PC503_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF2526592.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39555..40352
                     /locus_tag="PC503_000578"
     CDS             39555..40352
                     /locus_tag="PC503_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2526593.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40365..42467
                     /locus_tag="PC503_000579"
     CDS             40365..42467
                     /locus_tag="PC503_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF2526594.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42535..43014
                     /gene="rlmH"
                     /locus_tag="PC503_000580"
     CDS             42535..43014
                     /gene="rlmH"
                     /locus_tag="PC503_000580"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF2526595.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43163..43474
                     /locus_tag="PC503_000581"
     CDS             43163..43474
                     /locus_tag="PC503_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526596.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43522..43839
                     /locus_tag="PC503_000582"
     CDS             43522..43839
                     /locus_tag="PC503_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2526597.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44052..44753
                     /locus_tag="PC503_000583"
     CDS             44052..44753
                     /locus_tag="PC503_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2526598.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            44977..46278
                     /locus_tag="PC503_000584"
     CDS             44977..46278
                     /locus_tag="PC503_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526599.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46415..47509
                     /locus_tag="PC503_000585"
     CDS             46415..47509
                     /locus_tag="PC503_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2526600.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            47511..48644
                     /locus_tag="PC503_000586"
     CDS             47511..48644
                     /locus_tag="PC503_000586"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF2526601.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48662..49771
                     /locus_tag="PC503_000587"
     CDS             48662..49771
                     /locus_tag="PC503_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF2526602.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49836..50576
                     /locus_tag="PC503_000588"
     CDS             49836..50576
                     /locus_tag="PC503_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF2526603.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50581..51573
                     /locus_tag="PC503_000589"
     CDS             50581..51573
                     /locus_tag="PC503_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF2526604.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51761..52642)
                     /locus_tag="PC503_000590"
     CDS             complement(51761..52642)
                     /locus_tag="PC503_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2526605.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52915..54303
                     /locus_tag="PC503_000591"
     CDS             52915..54303
                     /locus_tag="PC503_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526606.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYANGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54331..55284
                     /locus_tag="PC503_000592"
     CDS             54331..55284
                     /locus_tag="PC503_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2526607.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            55344..55568
                     /locus_tag="PC503_000593"
     CDS             55344..55568
                     /locus_tag="PC503_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526608.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55561..56073
                     /locus_tag="PC503_000594"
     CDS             55561..56073
                     /locus_tag="PC503_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF2526609.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            56105..56959
                     /locus_tag="PC503_000595"
     CDS             56105..56959
                     /locus_tag="PC503_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF2526610.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57493..58287
                     /locus_tag="PC503_000596"
     CDS             57493..58287
                     /locus_tag="PC503_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2526611.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            58391..59197
                     /locus_tag="PC503_000597"
     CDS             58391..59197
                     /locus_tag="PC503_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2526612.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            59259..59780
                     /locus_tag="PC503_000598"
     CDS             59259..59780
                     /locus_tag="PC503_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2526613.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            60195..62282
                     /locus_tag="PC503_000599"
     CDS             60195..62282
                     /locus_tag="PC503_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2526614.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            62297..62584
                     /locus_tag="PC503_000600"
     CDS             62297..62584
                     /locus_tag="PC503_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526615.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            62611..63882
                     /locus_tag="PC503_000601"
     CDS             62611..63882
                     /locus_tag="PC503_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF2526616.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            63940..64539
                     /locus_tag="PC503_000602"
     CDS             63940..64539
                     /locus_tag="PC503_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2526617.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            64544..65449
                     /gene="dapA"
                     /locus_tag="PC503_000603"
     CDS             64544..65449
                     /gene="dapA"
                     /locus_tag="PC503_000603"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2526618.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            65555..66187
                     /locus_tag="PC503_000604"
     CDS             65555..66187
                     /locus_tag="PC503_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF2526619.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNVRKI"
     gene            66664..69171
                     /locus_tag="PC503_000605"
     CDS             66664..69171
                     /locus_tag="PC503_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2526620.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            69513..71675
                     /locus_tag="PC503_000606"
     CDS             69513..71675
                     /locus_tag="PC503_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF2526621.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            71680..72297
                     /locus_tag="PC503_000607"
     CDS             71680..72297
                     /locus_tag="PC503_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526622.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            72486..72830
                     /locus_tag="PC503_000608"
     CDS             72486..72830
                     /locus_tag="PC503_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF2526623.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            73400..74266
                     /locus_tag="PC503_000609"
     CDS             73400..74266
                     /locus_tag="PC503_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2526624.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            74379..74783
                     /locus_tag="PC503_000610"
     CDS             74379..74783
                     /locus_tag="PC503_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF2526625.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            74947..75396
                     /locus_tag="PC503_000611"
     CDS             74947..75396
                     /locus_tag="PC503_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2526626.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(75552..75929)
                     /locus_tag="PC503_000612"
     CDS             complement(75552..75929)
                     /locus_tag="PC503_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2526627.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            76191..77108
                     /locus_tag="PC503_000613"
     CDS             76191..77108
                     /locus_tag="PC503_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF2526628.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            77592..79010
                     /locus_tag="PC503_000614"
     CDS             77592..79010
                     /locus_tag="PC503_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2526629.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            79086..79898
                     /locus_tag="PC503_000615"
     CDS             79086..79898
                     /locus_tag="PC503_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2526630.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            80321..80938
                     /locus_tag="PC503_000616"
     CDS             80321..80938
                     /locus_tag="PC503_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF2526631.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(81095..81547)
                     /locus_tag="PC503_000617"
     CDS             complement(81095..81547)
                     /locus_tag="PC503_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HDF2526632.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            81995..83353
                     /locus_tag="PC503_000618"
     CDS             81995..83353
                     /locus_tag="PC503_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2526633.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            83626..84006
                     /locus_tag="PC503_000619"
     CDS             83626..84006
                     /locus_tag="PC503_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2526634.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            84131..84331
                     /locus_tag="PC503_000620"
     CDS             84131..84331
                     /locus_tag="PC503_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526635.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            84527..85255
                     /locus_tag="PC503_000621"
     CDS             84527..85255
                     /locus_tag="PC503_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2526636.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            85277..86194
                     /locus_tag="PC503_000622"
     CDS             85277..86194
                     /locus_tag="PC503_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF2526637.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            86336..87520
                     /locus_tag="PC503_000623"
     CDS             86336..87520
                     /locus_tag="PC503_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2526638.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTYLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            87627..87815
                     /locus_tag="PC503_000624"
     CDS             87627..87815
                     /locus_tag="PC503_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2526639.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            87964..88614
                     /locus_tag="PC503_000625"
     CDS             87964..88614
                     /locus_tag="PC503_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2526640.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            88717..89655
                     /locus_tag="PC503_000626"
     CDS             88717..89655
                     /locus_tag="PC503_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2526641.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            89681..90532
                     /locus_tag="PC503_000627"
     CDS             89681..90532
                     /locus_tag="PC503_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2526642.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDSIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
BASE COUNT        34921 a        10423 c        15224 g        30064 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata ccatctttaa aacagtaggt caatactttt
       61 tttatatttt tttataaatt tttttcatat tcttttttca gcttctctac tacctttttc
      121 tctagtctag aaacagtcat ctgtgatatc cctagttctt tagctatact agattgtgtt
      181 ttatcaaaga aaaatctatc tttaaaaatt ttaacttcta attcatttaa agtttcaata
      241 aacttattaa taaaatcttc atactctata cttccaaagt taccttcttc ttttccaatc
      301 ttatcaataa gagttatatc tttatcctct gaatcatcat tacttgatga atccaaagac
      361 attggttgat atccataaga agcctccata gcctctaaaa catcttcttc actaacgcct
      421 atataatcag ctatatcttt tacctttgga tgcttcttat tttcttgttc taatttaatc
      481 ttcgcatcac ttatcttttt gcttaattcc tgtattcttc ttgggactct aagtgtccat
      541 accttatctc taaaatactt ttttatttct cctactatag ttggtgttgc aaagctggag
      601 aactcaaatc ctttctcaac atcatatcta tcaatagcat aaattaatgc caatgaagca
      661 acttgatata tatcttcaaa atcaacacct ttgtttatat acttcttagc taacaatctt
      721 gctaaataca gatgtctttc aataagaata tttctaatgt ctacattttt atttttatta
      781 tataaattaa atagctcttt tgtatccata tttaggtaat gtgtagcatt agctacattt
      841 ttcattaaat atcaactcct aaatatttag tcatttttat ttttgtccct tgattatgtt
      901 ctgattcaat atctacatca tccattaaag ttttaattat aaacaatcca agaccactct
      961 cttttggatt ctctaaatct ggtgtactta ttgagctaac atcatatcct tttccattat
     1021 cttgaatttc tatattaatt gcattatcta aaatattaaa tactatatta aacacatcat
     1081 ctttactgtg ttttattgca tttgtacatg cttcagatac tgctaccttt atatcttcta
     1141 tatcatctat tggaaaaccc atcttattgg caattccaga tgctgttaat cttattatac
     1201 taacataatc tggatttgta gtaatttcca tctttatagt ctcacaagcc aaagtttatc
     1261 cctccacttt aaatatttta tctagacctg ttatagtaaa aatctttctt acgttactct
     1321 taggatttac tatgtatatc tctttttcat ttatttttaa tttttttaat acacctatca
     1381 tagctcctaa gcctgttgag tctatataat ctaaatcttt aagattaatc tttacatcta
     1441 acatattttt ttctattaaa gcatgtaaat gttcctttag tttatctgct gtagaaacat
     1501 caagttctcc atcaagacaa acattccaaa atttattttg tgaatctaaa tttgaatcaa
     1561 tattcataga catgtaaaaa cctcctattt ccttttaata attttaaata tatttcctat
     1621 actcaatatt ttattaatta cataaactat atcatctatt ccctttgata ttgatgatgc
     1681 attttcaaca atatcttgta tatgtctttc attataatct acaatcttat atgccttttc
     1741 aacaacctta tttatgctgt ttagagtttt agctaaataa attgctacta taagagcaga
     1801 gcttcctact aacactgctc caatttgcca cccccatgca ttcattagtt aacatctccc
     1861 tcatcatcaa agcttttact tattactata tcttcttctg aaatctttat atcttcttca
     1921 ttattatcat catccactaa atttattatt ctctctttaa catcattaaa tgtttcatgt
     1981 agaacttctt ttggattttc tttgacatca ttaaacttct cttttgtttc ttttcttagt
     2041 tcagaacctt ttttaggtgc aaaaaacata ccaaatataa accctaaaat agctcctaat
     2101 aataaaaatc cacctttttt acaacttctt ttattgcaca taacaattac tcctttcaat
     2161 tttaaatttt tatctaacta cattatacaa aaagaatagg atatttatcc tattcttctt
     2221 caatatttat tttggcaatc gaaactacat tgacttcatc attcgtcttc attaatttaa
     2281 caccacttgt aactcttcca aacagtgata tttcattgac tcttattcta ataagaactc
     2341 catcagaatt tataatcatt atctcatcat cttcgttgac catatctgca cctacaattg
     2401 taccagtttt ttcagatata ttataagttt taattccttt accagctctt atttgacttc
     2461 tatactcttc tatatttgtt ctctttccaa aaccattctt acttacaact aacacatctg
     2521 tacctttact gcaaaggttc atagacacaa caaaatcttc tttacttaaa gttatacctt
     2581 ttacacccat tgctgttcta cccatatatc ttatatcatt ttcatcaaat cttatagaca
     2641 taccttcttt agttactaaa agtacttctt gttttccatc tgtaagttct actccaataa
     2701 gctcatcatc atctcttaaa cctattgcaa taagaccaga tttatttata tttttgaact
     2761 cttctctctt agtcttttta acaatacctt ttttcgttgc aagtaataaa tattcatttt
     2821 catcattacc atcaataggt attagagtag caattttctc atctgctgac aattgaagta
     2881 aattcactat agcagtacct ttagcctgtc tcttaccttc tggtatttca tatgcattta
     2941 atttaaatac tctaccttta tttgtaaaga ataatagtct actatgagta gttgtagtta
     3001 ccaagtgcct tacaaaatct tcttctctag ttgtaagtgc tgaaatacct cttccacccc
     3061 ttttttgact cttataagta tcagatggaa gcctttttat atatccaaag tgagtaagag
     3121 ttattgctat ttcttcatca cttataagat ctctcatatc tatttcgcct tcagcatgtc
     3181 ttatttctgt tcttctctca tcagagtaat tttcttttat tattgtaatt tcatccttta
     3241 ttacatttaa aagtaatctt tcatcagcta aaatctcttt taatctattt atcttcttga
     3301 ttaaatcttc atattcagct tctatcttat ctctttctaa acctgtaagt ctttgaagtc
     3361 tcatatctaa tatagcttgt gcttggattt cagttaattt gaatttttct attaaaccta
     3421 gcttagcttc ttgcccagtc tttgaagctc ttatcaagct tataacagca tctatattat
     3481 ctaaagcaat ctttaatcct tctaaaatat gtgctcttgc ttcagcttta tttagttcaa
     3541 atttagttct tcttgtaaca acatcttctt gatgtttaat ataatgatat aatatttgtt
     3601 taagatttaa aactcttggc tgaccatcta caagtgcaag cattattata ctaaaagtat
     3661 cttccatttg agaatgttta tacaaattat ttaatactat attagcatta gcatccctct
     3721 ttaattctat aacaattctc ataccatttc tattactttc gtctcttagg tctgatatac
     3781 cttctattct cttttcttta actaactctg ctattctttc aaccagttta gccttattta
     3841 cttgataagg tatttctgta actattattt gctgttttcc ttttggtagc tcttctataa
     3901 aagctctaga cctaacttta acttttcctc ttccagttct gtatgcttct gctatacttt
     3961 cttttcccat tataattgca gctgtaggga aatctggtcc ttgaacaaat tttattaaat
     4021 catctacact acactctgga ttatctatca aatatacagt tgcatcaatt acttctgcta
     4081 aattatgtgg aggtattgaa gttgccatac caacagctat accatttgag ccatttacta
     4141 ataaattagg atatctagct ggcaatactg aaggctcttt taacgactca tcaaagtttg
     4201 gtttaaagtc tacagtttcc ttttcaatat ctctcagtag ttctaatgat aatttactca
     4261 ttttagcttc tgtataacgc atagcagctg gtgaatcccc atcaacagaa ccaaagttac
     4321 catgaccatc tactaaaagt gctctagttg aaaaatcttg tgccattctt accatagcat
     4381 aataaacagc agtatctcca tgaggatggt acttacctaa aacgtcccca acaatacgag
     4441 ctgacttcct gtatggttta tctggagtta aatttaactc actcattgaa tataatattc
     4501 ttctatgaac tggctttaaa ccatctctaa catcaggaag agcacgtcca gctataacac
     4561 tcattgaata atcaatatac gattttttca tttcttccgc tatttcaata gggagtattt
     4621 tgttattttc ttccatgtat actaatcccc tctctctata tatctaagtt tctaacaaat
     4681 cttgcatttt cttctataaa ttcttttctt ggagcaacct tatcacccat aagcattgaa
     4741 aatacttcat ctgcaattgc agcatcttct acagtaactt gtaataaagt tcttgtctca
     4801 ggattcatag ttgtttccca taattgctct gcattcatct ctccaagacc tttgtacctt
     4861 tgaagttcaa caccatttct tccaatttca tctagtaaga tatttaactc tttatctgag
     4921 taaacataat gttccttctt ttgctttgtc actttatata aaggtggctg tgctgcataa
     4981 acatacccct catctataag aggtctcata tatctaaaga agaatgttaa taataaagtt
     5041 cttatatggg ctccgtctac atcagcatcg gtcataatta taattttatg atacctagcc
     5101 ttatctatat caaaatcttc tccaatacca caaccataag ctgttatcat attttttatt
     5161 tcatctgaag atagtatcct atctagtctt gatttctcaa cattaagtat tttccctctt
     5221 aatggaagta tagcttgact atttctatct ctaccttgtt tagctgaacc tcccgctgaa
     5281 tccccttcga ctaagaatat ttcactttta gatggatctt tttctgcaca atctgcaagt
     5341 tttccaggta aagatgtact ttctaataca ctttttctcc ttgttaattc tcttgctttt
     5401 tttgcagctt ctctagctct ttgtgctctt aaagctttat caactatgat tcttgctgtt
     5461 gatgggtttt cttctaggaa agaccccagt tcatcaactg ttacactatc aactatacct
     5521 ctcataaagc tattacctag ctttgtttta gtttgacctt caaattgagg ttctggtaat
     5581 ttaactgata ctactgctgt aagaccttct cttatgtctt caccaagtag gttaacatca
     5641 ttttccttta aaaatttatt tctcttagca taatcattta cagttttagt aagagctgct
     5701 ttaaatccac ttaaatgaga accaccttca tgtgtattta tattgtttgc aaaagaatat
     5761 atgttctctg tataaccatc tgtatattgc atagctagtt caacaaaaca atcatcaacc
     5821 tttttatcta tataaactat gtcatcatgt ataccagttc tagatttatt taaatactta
     5881 atatattcta ccaaaccacc tgtatagtga aattcttttc ttttttcttg tccttctctt
     5941 ttatcttcaa atactatttt tattccttta ttcaagaaag aaagttctct aagcctatac
     6001 tccaatgttt catatttaaa ctctatttca tcaaatattg tctcatctgg cataaattga
     6061 atcattgttc ctttatcttg agattctcca actacttcaa gcttagatgt tggcaatcct
     6121 ttctcatatg tctgcttata tatctttccg tttaaataaa cctctgctac catccatttt
     6181 gacaatgcat taactacaga aacaccaact ccatgaagac ctccagatac tttatatcct
     6241 ccgcctccaa actttcctcc tgcatgaaga ttagttaata ctgtttctaa agttgattta
     6301 ccagttttag gatgtatttc aacaggtata cctcttccgt tatcttttac taaaacactg
     6361 ccatcttcat taatagatac atatatgtct gaacaatatc cttgtaaagc ctcatctata
     6421 ctattatcta caacttcata aactaagtga tgtaaacctc tagggcttgt actaccaata
     6481 tacatacctg gtctttttct aacggcttct aatccctcta atacttgtat ctgacttgca
     6541 ccgtattctt gtttcattta atttcctcca ttctctatgc taataacatc gccattttca
     6601 atattaaata ttgtaacatt tttttcatca aatatttttt tatgtgaaac ttcagcactt
     6661 gttataaaca tttgaacatt gcttaaatta tttactaaaa gtttttgtct tgcttcatct
     6721 aactcactaa aaacatcatc taaaattaat actggatatt cttcaacttc attttttatt
     6781 aattctatct ctgataactt taatgatatt gaagcagttc tttgttgacc ttgtgaacca
     6841 aaaagtcttg catctaaatc atttatgaat atatttaagt catctttgtg tataccatat
     6901 ctggtagtct tagattctat atcattaggt ctattcgatg acaacttggc taaaaattta
     6961 ttatatactg tatctatagt atcttcatca gttatattta tttgattttt atatcgaatt
     7021 gataatcttt caactccatt agtcaaattc atatgcatat tttcagatat attagctatc
     7081 ttttttataa agtctctacg caaaatataa atataacttc catactttgc taacgtatca
     7141 tcatatacat ctaataaagc ttcatcaaca tgtatatttt taagcaccct actcctttga
     7201 gaaagtgttt tattataatt ggtaagatat ttataatatt taggtataat ctgactaatc
     7261 tctttgtcta taaatgccct tctttcttta ggaccctctt taaccaacct taaatcctca
     7321 ggagaaaata taacaacatt taagttgcca agtagttctt gtatcttttg taaaggaact
     7381 ttatttattc ttatcccttt tttatctttt ccaataatta gctctattag actatattta
     7441 ttatattttg aaaaacttcc tccaatatat aagttttcac tattaaatct aaccatttct
     7501 ttatctttgt tagtcctaaa tgattttcca aaagaaagca tataaataga ttctactata
     7561 tttgtctttc cttgaccatt tttaccaaca agtagattta ctttcccatt aaattccaga
     7621 tgcaactttt tataatttct aaaattaaca agttgcaaac ttttaagttt cacaaaaagt
     7681 tctccttttt ttacaatact tttattttag ttccttctat ttcaactata tctcctgatt
     7741 ttatcttttt tcctcttctt aattctattt catcatttac tgtcactaaa ccttcttgaa
     7801 ttaaaaattt tgcatgacct cctgttgatg caatctctgc taatttaaga aattgatcca
     7861 actttatata ttctgattct atagttattt cagtcataat agttcctcct tgtcactatt
     7921 ttaaacaaat tcctattgat acactaaaag tatattatac cataaatatg cttataaaag
     7981 gagttgtcta agattagaaa aattttctac aaaagacaac tccttcatgt ctgctatata
     8041 tttgatgata ttcttactgg aagcagtaag taaatataat taacatcatc tgttggttta
     8101 attatacaag gatttacatt tgtagtaaat tctataaata tttcctcatt atctatattt
     8161 ttcaaacctt cgataaaata tctagaattg aaagctatat ctaggtaatc tccatctaaa
     8221 tctatttcaa cttcttcata cacatttcct ttttctgtat tagaagtaat tgccattact
     8281 ttatctctta tagataactt tataagatta tttttttctg attgagacaa taaagacgct
     8341 ctctctatac tatttaaaag ttccttagta tttaatttaa ctctgctgtt atgttctctt
     8401 ggcaataatt ttttataatc aataaaatct ccttcaagca atcttgtaat aattttcgta
     8461 tcattaatta taaaaatagc atttttttca ttaaatccaa ctttaacatt atcctctcca
     8521 gaaagcaaac tatttacatc tataagtgtc tttccaggaa ttatgacttt tatattttca
     8581 gttaaactat caaccgaaca actttttaca gctaatctat atccatcaat tgctactaaa
     8641 tttaagtttc tatctacaat ttctaaaagt tctcccatta aaacaggttt tgtttggtcc
     8701 tgtgagatag caaatacagt ttgtttaatc atatttttta ggatttcttg aggtatgcta
     8761 tataaatctt cttcatttaa ttctggtaat ttaggaaatt cttttgctgc ataaccttta
     8821 attttaaatc ttgaatttac acaatttatg taaatattat tttctgaatc agtttctatc
     8881 tcaacaaagg aatctggtaa ttttctaatt atatctccaa atagccttgc atctacaaca
     8941 acatcacctt tttctatgat ttctgcttgt acataagttt ctattcctat ttcagcatca
     9001 tatccagtaa gttttaattg accttcttct gtagatataa gtataccttt taataattct
     9061 attgttgttt ttccattaat agctttttga gcaattccaa ttctatttgc taggattttt
     9121 tgattacaaa ttattttcaa tgtggataac ctcctctggc tttttatata taaaaataag
     9181 ttaaaatcat agtagtaata gtagtaggtg ttgttgataa tgttaataag tatgtataac
     9241 attataaata caaagatatt aacatgtgta taagatgtta atatctttgt tattttagac
     9301 ttgataattt gttaataatt tttgttcaaa aaaagtatta acaggttatt caagagatat
     9361 aaacatacaa ttgtgtataa attatccctt caaatctgat ataattttgt ctattttagt
     9421 cttaatttct tcactttctt ctatatcctt agatactttg tcatgagcat gaattactgt
     9481 tgtatggtct ctacccccaa actcttcacc tattttagga agggataaat cagtaagctc
     9541 gcgcgttaaa tacatagcta tctgtcttgg ataagctatt gaacgtgttc tttttttaga
     9601 attaaaatct tccatcttta aattgaatac agaagatact ttttctttta ttctgagaac
     9661 atttatttct tcatttttag aagttgttat aatatctttt aaagcttctg tagcaagatc
     9721 aaaagatatt accctattgc taagagaaga ataagcaacc actctagtta atgcaccttc
     9781 tagttccctt atgtttgact taatattttt tgctatatat gacataacct catttggcac
     9841 atctatacgt tctagttgag ccttttttct aagtatagca attcttgtct caaagtcagg
     9901 tgcttgaata tcagttataa gtcccatttc aaatctcgat cttagcctat cttctagtgt
     9961 aggtatgtct tttggcggtc tatcactaga tataattatt tgtttgtttg cttcatgaag
    10021 agtattgaat gtatggaaaa actcttcttg agttctttct tttcctgcta taaattgaat
    10081 atcgtcgatt agtaatacat ctacgtttct atatttattc ctaaattctt cgtttttatc
    10141 gtcttttata gagtttataa gttcattagt aaatttttct gaagaaacgt aaactacttt
    10201 tgagtctttt ttttgactaa caatatgatg acctatagca tgcattaggt gagtcttacc
    10261 taatccaact cctccataca aaaaaagtgg gttataagct ttagctggag attctgcaac
    10321 tgcaacgcat gcagcatgtg caaatctatt actattacca ataacgaatg tatcaaatgt
    10381 gtattttgga tttagattgg ggtaaagaac tctataattt aaatctgtgc tatcagaatt
    10441 taaatcagca acctcttttt cgctcaatac aaatttaata ttatattttt ttaatgacag
    10501 ttgactaata gcatcttcaa ttaaatgtaa atatctattc tctaagatat ctttattaaa
    10561 atcactagga gccagtaaga ttaaatcatt aagatgtatt tttaatggta cgatgttttt
    10621 aaaaaaggta ttaaaactta ctgaagttaa gtcacctttt attaattgta gggttttgtc
    10681 ccataaagaa actatatcca taatataaac ctccgaacag aataattaat attttccaca
    10741 aagttattaa cagaaaagca aaaatatata taaattttac agaataacta aatttatgga
    10801 taatggtgtt gataaattaa taatagtata aattattaaa aaaatatgaa aagatataaa
    10861 caatatgtag ataaagttat aaataacata aacatacaat aaatggtgat tataactaga
    10921 gtattgtcag taatcttaaa agttatacac aaaagtatcc acaagctgtg aataatttct
    10981 aataagttga taacatttat gcacattatc aacaagtata tttataatat caaaatatat
    11041 gtcaaacttc aatgatttgt aactaattta tccacaatat taactaattg ttgataaaaa
    11101 tataaacatg ttaaaattac tttatttgtg tatataattg aaaaaaataa tttagaataa
    11161 aattaaatag atttttacta gtattttcaa taaaaaaaat acataatata tatatggtag
    11221 attttgtgat ataagcgtcc caaaaactcg ttgacaacag tagtaaaagt atttataatt
    11281 atatgtgtta tgtttacttt gagggtaaag ttattatttt tataaacgga aaataaaatc
    11341 tgaaaggcgg tgcaaaataa tgagtaaaag aacttatcaa ccaaaaaaga gacaaagaag
    11401 taaagaacat ggtttcagaa aaagaatgaa gacgtctaac ggaagaaacg tgttaaagag
    11461 aagaagagct aaaggaagaa atagattaac tcattaatta caaaagggcc gctgcaaagg
    11521 tggccttttt gtgtaaataa ttacaattca tagctgtgtt tatggaggtt aactatggac
    11581 tttaatagga ctaaagggtt gaaaaaagac tctgatttta gaaaagtata taaacacggc
    11641 aaatcttttg caaacaaata tttagtaata tatatactta aaaataaatc agattatagt
    11701 agagtaggta tttctgtttc aaaaaaagta ggaaaagcta ttactaggaa tagagtaaga
    11761 agattaataa aagaagccta cagattaaat attgatgaaa aaattaagcc tggatatgat
    11821 atagtattta tagcaagggt atctagtaag gatgctactt ttaaagacat agacaagtct
    11881 ataaaaaatt tagttaaaag aacggatatt tctatttaat tgtatgctat aaatatggag
    11941 gttaatgact ttgaataaaa taatttatat attaaaggaa ataagtaagt atttatcgaa
    12001 tttatgtatt tatttagtga gattttatca aaagtatata tctcccttaa agggacctac
    12061 ctgtagattt tatccaactt gctcacaata ttcaatagag gcgtttaaga aatatggatt
    12121 tgtaaaaggt atgtatttaa cgataagaag aattttaaaa tgtcatcctt ttcatccagg
    12181 aggttacgac cctctaaaat aaaagagagt aactattagg aggtataaaa aaattgaata
    12241 taataggaaa tttcttagga ttgattctta aggtaatatt tgaatttgtt aatcattatg
    12301 gtatttctat aatacttttt acgatacttg taaagattat tttattacca ttaacaatta
    12361 agcagactaa gtcaacaaag gcaatgcaag atatacaacc tcgtataaaa gagatacaag
    12421 aaaaatataa aaataagcca gaaaaacaaa atgaagaaat tgttaagtta tatggagaag
    12481 ctaaaattaa tccactatct ggttgtttac ctttattaat acagtttcct atattaatag
    12541 gattatttag cgttttgaga gaaccagttg ctcatggcgt ttttgcaaac aaagctgcat
    12601 ttttagcagc tgacaatggg tttttatgga taaaaagctt aacatcacca gattatgtat
    12661 tagcagtatt ttcaggagca agtgcatatg tcatgcaaaa agtaatgaca ccaaaagatc
    12721 agttacaagg ctctatgaaa gtaatgacat atgtaatggc aggtatgtct ttctattggg
    12781 gatttatatt cccagcagga cttacattgt actggacagt aagtaactta ttctcaatag
    12841 ctcaatatta cttaataatg aatcctttaa aagctaaact ggctgctaac tctaaggagg
    12901 aaaaagttaa tgagaaaaag cctaaaatta ataaaaagta agagtaaaga ggaagctata
    12961 agtaaagcta tagcagagtt gaatttaaaa gcagaggata tagaagtaga aatacttgaa
    13021 aatccaagta aagggttttt aggttttata ggtgctaaag atggtactta tgaaattttt
    13081 gttatcgaga gggaagtaga tgtagctaaa aattttatag aggtaatgtt gaaaaatgca
    13141 aatgttgatg ccaaagtcaa tgtatctcaa aaagataatt taatcatggt tgatattgaa
    13201 ggcaaagaag ctgcaagttt aattggtaga agaggggaaa ctttagattc tattcaattt
    13261 ttgactggat tagctcttaa taaaataaat aaagattctc atacaagagt acttgtagat
    13321 atagaaaatt atagatcaaa acgagaagaa tctttaataa gatatgctaa taaagttgct
    13381 agagaagtag cgaaaacaag aaaaactaaa aaattagatt atatgaatcc atatgagaga
    13441 agaataatac attcagctct tcaaaatgac aaatatgtaa ttacatatag tgaaggaacc
    13501 gatccatata gaagattagt aattgagtgt aaaagataaa gtcaacctcc taaacattag
    13561 ggggttttat tttttaatat tattaaatca ttaatgattg gttaaatgta aatctatatg
    13621 taaaaaatta tgaattaaga ggtgataaat ttgtttatag atgatacaat tgcagcaata
    13681 gctacagcac ctggagaagg tggtataggt atacttagaa taagtggaga aaaagctttg
    13741 aaggttgcag aagaaatctt taaatctatg tctggaaaga gtattgaaga atacaataag
    13801 agaacattaa tatatggaaa tatagtggat aatgaaaata taattgatga agttttattg
    13861 gcatatatga aaggaccaaa ttcctataca ggagaagatg ttatagaaat taattgccat
    13921 ggtggattta tttcggtaaa gaagatatta gaattaatac tatcaaaaga tgttagatta
    13981 gcagaggctg gtgagtttac taaaagagca ttcttaaatg gaagaataga tttatctcaa
    14041 gcagaggctg taattgatgt tataaaagcc aaaactgata tagctcatga agttgctcaa
    14101 aatcaattag aaggttcttt atcaaagaag ataagagaat tgagagataa agtcactgag
    14161 atattagctc atgtagaagt tgctatagat tatcctgagg aagatattga gcatataaca
    14221 tatcaaactc ttaaagaaaa aactgatgaa cttaaaaaag acattaaaaa attatatgat
    14281 acagctgaaa gtggaaaaat acttagagaa ggcttaaaga cggtaattgt tgggaaacca
    14341 aatgtaggta aatcttcact acttaattct attttaggag agaatagagc aatagttact
    14401 gatataccag gaactactag agatgttata gaagagtttg taaacataaa aggtatacct
    14461 ttaaaaattg ttgacacagc aggtataaga gatactgatg atattgttga aaaaataggt
    14521 gttgaaaagt ctaaagaatc atttactagt gcagatttga tagtaatggt tttagatgca
    14581 tctagaaagt tgtcagaaga agatatagag atattagaaa aacttaagga taaacaaaca
    14641 atagtgctgt taaataagaa tgatttgaaa caagagattg aagaagaaaa aatacttaaa
    14701 tatgtagaaa ataatagtat aataaaaata tcagctttac aacaagaagg aatagaagaa
    14761 ttgcaagata aaatagagtc tatggtatat aaaggtagta tcaaaaataa ttctagttta
    14821 gtagtaacaa attcaagaca taaagatgca cttagtaaag catataaatc tgcaacagat
    14881 gctttaattg ctttggaaca aagtatgcca tttgactttg tagaagtcga tttaaaaaat
    14941 atatgggact atcttggata tattaatggt gatacagtaa cagaggattt actagataat
    15001 atattccata atttctgtat tggtaagtaa tgtacaaaag taaacttgtt tttattatag
    15061 agatttttaa aaaatttgaa gtgtttctca tgaaacatta attttgaaaa gaaaggaatt
    15121 ataaatgata aagtttgaag caggaaaata tgatgttata gtagtcggag caggacatgc
    15181 tggatgtgaa gctgctttgg ctactgcaag aatgggatat aaaactttga taataacaat
    15241 gtctttggat tccatagcat taatgccttg taatccatca attggaggga ctggtaaagg
    15301 tcaattagtt aaagaaatag atgccttagg tggtcagatg ggattaaata tagacaagac
    15361 atatatacaa agtagaatgt taaatactgc caaaggtcca gcggtacact ctttaagagc
    15421 acaagcagat aaatttaaat atcatgaaga aatgaaaaag acattagaag atgaaccaaa
    15481 tcttgatata gctatggatg aagttgtaga aatacttcat gaaggaaatg ttgtaatagg
    15541 agttggaact aaactaggat gttcatttaa atctaaagct gtaatattgg ccactggagt
    15601 ttatctgaac tcaaagatat atatgggtga agttgcattt tatgaaggtc ctaatgcatt
    15661 ggggtatgca aaatatctta cagatagctt agttgagctt ggccttagaa tgagaagatt
    15721 taagacggga actccagcaa gagttcatag agatagtata gacttctctg taatgtcttt
    15781 acaagagggt gatgaaaaag taactccatt ctcatttatg aatgaaaata tagaaaaaaa
    15841 acaagaacct tgttatttaa caagaactac agaagaaact caaaaagtta tactggataa
    15901 tttaaaaagg tctgctatgt atagtggagt aatagaaagt actggtccaa gatactgtcc
    15961 ttctatagaa gataaagtag taagatttag tgataaaaca tcacatcaat tatttataga
    16021 accagaaggg ttaaatacta aagaaatgta tatacaagga atttcaacta gtttaccttt
    16081 tgaagttcaa ttagatatgt acaaaactat aaagggactt gaaaattgta agataatgag
    16141 acctgcatat gctattgaat atgattgtgt tgacccaact caactaaaaa taagtttgga
    16201 aataaagggt gttgagaact tatttagtgc agggcaattt aatggaactt ctggatacga
    16261 ggaagcagca gctcaagggc ttatggctgg tataaatgca gttagaaaga tagaaggaaa
    16321 agagccattt gtattagacc gttcagaagc ttatataggt gtcttattag atgaccttgt
    16381 tactaaagga actaacgagc cttacagaat gatgacatca agagcagaat atcgactata
    16441 tttaagacaa gataatgcag atatgagatt aactcaaaaa ggttatgata taggattagt
    16501 taaaaaagat agatatgaaa ggttcctaaa taaaaaggct gctgtagaga aagaatttga
    16561 aagactaaaa aatgaaagag ttacaccaaa agaagtaaat agtttgttag aagaaaaagg
    16621 agcaacacca ataaaggttg gaatatctct atatgaattt ttaaagagac cagaggttac
    16681 ttacgaattg cttgaagaat tagggaaagg cgctggagaa gatgtttcaa gagaagttaa
    16741 agaacagtgt gtaataataa ctaaatatga aggttatata gagaaacaat tgaaacaaat
    16801 agaccaattt aaaaaacttg agaataaaaa gctggatgag aaaataaatt attcatctat
    16861 agaaggtctt agattagagg ctagacagaa actagatgat ataaaaccta tttcaatagg
    16921 gcaagcatct cgtatatctg gtgtttctcc agctgatata tcagttttac ttatatacct
    16981 agaacaaatc agaagaacta gaggtggcaa aggtgaataa tatagaactt ctgaaaaacg
    17041 ggattgaagg ttttaatata gatacgaatg acagtatgtt agaaaaattt aaaatctata
    17101 gagagatatt agttgactgg aataaaaaga tgaatcttac tggaatagaa gatgaaaaag
    17161 aagtgtatat aaaacatttt ttagactcta tttcagctgt aaagaatgga tatataaaaa
    17221 atgggatgtc tataatagat gttggtacag gtgctggttt tcctggaata ccattgaaaa
    17281 tatgtttaga tagcttagaa cttactttgt tagattcgtt aaataaaaga ataaactttt
    17341 tagaggaagt tagtagagta ctagagttag ataatattac atttatacat ggaagagctg
    17401 aagattttgg taaagatgaa gactataggg aaaaatatga tgttgctacg gcaagagctg
    17461 ttgctggatt accgattctt atggaatttt gtgtaccatt tgtaaaagtt ggagggtatt
    17521 ttatttgctt aaaaggtccg aatgctaatt tagagctaga agaatcacaa aaggctattg
    17581 atgttttagg attggagtat attgaaaaaa tagatgtaga gttaccagag gtagatttaa
    17641 atcataatat attagttttt aaaaaagtga tggaaacacc agttaagtac cctagaaaag
    17701 ctggtaaacc agccaaaaat cctattaagt aatgaaaaat ttattattgg taagcttaat
    17761 tatttctcag gaaataatta agcttactgt aaaaaaacaa aaataaagga attattaaag
    17821 tagatgcaga aataaatttg tatgtacata tagagaacaa aaataattta tatctaaaat
    17881 aagagaggta tgttatggaa gataaaagag ttatggagat acctatagaa gatgtagttc
    17941 caaatccata tcaaccaaga aaaatatttt cacaagtttc attggaggaa ttgagcaatt
    18001 ctataaaggt atatggtata attcaaccta taacagttag agcaaaagat ggcaaatatg
    18061 aactaattgc aggagaaaga agattaagag cagctaaatt agcagagctt aaaaccatac
    18121 cagcaattat aaataatatg aacgatgaat cttctgctgt tctagcgtta ttagaaaatt
    18181 tgcaacgaga agacttaaat ttcattgaag aagcaattgg ttatgaaaac ttaataaaag
    18241 aacatgcttt tactcaacag caattagcag aaaaattggg caaaaatcaa tctactgtag
    18301 caaataagct tagaatatta aagcttccaa acgatataaa aatgaagcta atagagaata
    18361 atttaacaga aagacatgct agagcatttc ttaaactacc aagtgaagat ttaatgcaaa
    18421 gtgtgttaga caaagtcata aaaaatgaat tgactgttaa aaaaacagaa aaattgatac
    18481 aagatgtatt agaagaaact aaagttcaag aagagcctga taaaaaacag aatataaagg
    18541 gtgctatgag tataagaatt tacataaata ctataaagca ggcctttgat gctatatcaa
    18601 atacaggaat tgatgctaag tataatgaaa tagataaggg agattatatg gaagttgttg
    18661 taaaaatccc taaaaaatag agattactgc ttaccagtaa tctttttttg taatataagc
    18721 cttgtaatat aaattgattt atagacatta tttatactta aaaaacacct attcaacatt
    18781 taaaattaat ttaattctta aaggggggaa catcatgggc aaagttatag ctgtattcaa
    18841 tcaaaagggt ggagtcggga aaactacaac aaatgtaaat ttaagtgcta gcttaggaac
    18901 tttgggaaag aaaatattag tattagattt agacccacaa ggaaatacaa ctagtggata
    18961 tggtattaat aaaaacgaag tagaaaatac aatctatgaa attatgttag atgggttaca
    19021 tattaaagaa gcaataataa gtactgaatt tgagaatgta gatgtagttc catcagctac
    19081 tgaactatca ggtgcagaga tagagcttac atctaaaact aatagagagt atattttaaa
    19141 aaattccata aaagcggtaa tagatgaata tgattatata tttttagatt gtccaccctc
    19201 actggggatg cttacaataa attgtttaac tgctgtagat agtgttttaa ttccaataca
    19261 atgtgaatat tatgctttag aaggtgttag tcaattaatg gagactataa aattagtaaa
    19321 atcaagatta aatgctgata tagaaattca aggtgttgtt ttaagtatgt ttgatggaag
    19381 agctaattta tcaatacaag tagttgaaga agttaagaaa tactttaaag gtagtgtata
    19441 tacaacttta attccaagaa atgtaagact tgcagaagct ccaagtcatg gaaaacctgt
    19501 aatttattat gataaaagat gtagagggtc tgtagcttat ttggagctag cagaagaatt
    19561 tatagattta gaagaggagg aatggtagta tggagaataa gtctaaaaga agtaatagat
    19621 taggtagagg tcttagtgca ttgataccag aaattaaagg agaaacttca gaaaaagaaa
    19681 tagtcaacat agatatagac aaaatatatc caaacgaagt tcaacctaga aagcaatttg
    19741 atgaagaaaa gataaaagta ttgtcggatt ctataaaaaa ttatggtgtt ttacagccaa
    19801 tagtggttaa aatggatgaa aataataaat atatgataat agctggagaa agaagattta
    19861 gagcatcaaa acttgcaaat aaaaatcaaa tacctgctat aattaaagat atagatatga
    19921 aagatataat ggagatagcc ttaattgaaa acttacagag ggaagattta aattcaatag
    19981 aagaggctct agcatataag agtttaatag agcattacaa tgtaactcag gaagaaatat
    20041 cagaagctgt tgggaagagt agacctcata taactaatac actaagactt ttaaatcttg
    20101 gacaagatgt tatagaaatg atagacagtg gtagaatcac agcaggccat ggtaaggctt
    20161 tattgagaat tgcagataaa gatttgcaac ttcaaatagc gaaaaaaata gaagaagaag
    20221 aactttctgt aagagaagtc gaaaatatag ctaaaaaaat atctgaaaat aaacaagaag
    20281 aacctaaaaa atctaaacct aaggatgtat ttattttaga tgttgaagat aaacttagaa
    20341 atatatttgg aacaaaggtg aatatttcta aaggaaagaa aaaaggtaaa atagagatag
    20401 aatactataa tgatgatgat ttaaatagta ttgtatcaat gcttcttgaa tagaacaaaa
    20461 atataaaaca gagaggaaga ttgttatgat ttatttagat aatgctgcaa ctacatatcc
    20521 aaaaccagaa agagtgtata atgctgtttt agattgtatg aaaaattatt gtgcaaatcc
    20581 aggtagagca ggccataaac ttgctatgag agctgctagg gagatatatg atacaagaga
    20641 gaatatagct aagttgttca atgtaagtaa tcctatgaat atagtattta catctaatgc
    20701 aacagattct ttaaatttag cgataaaagg tgtattacaa gaaggagacc atgtaataac
    20761 aacgtctatg gagcataatt cagtaataag acctataaaa gcattggaaa aaaggggtat
    20821 tgaaaatact gtagtaaaat gcgattatga gggattttta gattatgaag atttagaaaa
    20881 atcaataaag agtaatacta aactgattgt aacaacacat gcgtctaatg tatgtggaac
    20941 tttaatagat ataaaaaaag ttggagaaat agctaaaaaa cataatatac tatttttagt
    21001 agatgcatca caaacagcag gtgtttatga tatagacgta aatgaatgta atatagatat
    21061 gttggcaatg ccaggtcata aatgcttatt tggacctcaa ggaacaggta tattatatgt
    21121 aagagaaggg ttgaacttaa atatattaaa agaaggtgga acaggtagta aatcagaaga
    21181 aatagttcaa ccagagttat tcccagataa atatgaatca ggaactcata atactccagg
    21241 tatagcaggt cttaaccaag gtatactatt tatatttgaa agaggaatca acaatataag
    21301 acaacatgaa gaagaattat gtcaatatat gatagacaaa ttagaggaag taccagatat
    21361 aaagatatat ggaccaaagg acagtaaaaa aagagcatca gtaatagctc taaatatagg
    21421 agatatggat tctggagagg ttactttctt attagatagt gattataata tagcgactag
    21481 atcaggaata cattgttcac cactagcaca taccacttta ggtactttaa aacaaggtgc
    21541 agtaaggttt agtataggat atttcaacac aaaagatgag atagataaag cagtggaagc
    21601 tttgaaaaaa atttcaaaaa ataaatagca tgagatttaa taatatagaa ataaaaaaag
    21661 gggatatttc aaaataaaaa tttgaatcat ctcctttttt gtacaaaaaa gaaaaggggt
    21721 tcctaagaac ctctaatcta tttgataata gtttcaagaa attactttaa gtaatctcct
    21781 tcttcaagaa ctatatgacc actttcgtaa ttagaaccat caacagtaat ttttatttgt
    21841 tcaacattca tattttttat gtaagtacga gcaactgaat caagcattaa agtttctgca
    21901 tcactaccta agtttgactt tgtaaagtca gagctaacat ctaatatacc agtttttaca
    21961 ccatcaatgt cttttgtagt aaatgaattt aattttgcag attctggaac aactttaagt
    22021 ttttgaagtt cttcaaataa agtgttctca tcaattttat ttaaatcaac tttattttca
    22081 attaaatctg tcttatctac atcaaaagag taaatagtag ctgattgagt tttagtttct
    22141 tcttttggag taggtttagc tttgttatta ggaacctctt tttcagtatt gttttcttct
    22201 tttggttgct caacatttgt attgctctta gtttcttttt tagatgaatc acttccattt
    22261 tgagcattag tacaaccaac tgcgaatata gatatagata atatacttaa cactaacatt
    22321 attttcttat ttttcataaa aatttctcct ctcttaaaaa ctattcttat atataattat
    22381 agtcgttatg agcaaatata tgaatacaaa atagtaacaa atttaaaaaa tgatttattt
    22441 aaattaataa aactcaaaat aaactaaatt ttagtcattt ttatgggaaa tcatttaatg
    22501 tacagtgaaa atattgtaaa ataaaagtag tgtttttaaa ataaatataa gttataatta
    22561 tattataaaa aaatgtcttc aaaaggtggg aatagtatgg aaattttgag cttaggagaa
    22621 aagattaaaa aattaagaaa agaaaaaaac atgacattaa aagaattagc tggagatagg
    22681 ataacagcag cacaaataag ccatatagag agggataaat ctcatactag ttatgaactg
    22741 ttggaatatc taggcgataa gctagatgta agtgtagaat acttattaga gaccaaggaa
    22801 atgcaatcaa aaaagataac tgataattta atactacaga gcgaaattta tataaaagaa
    22861 aatgaattaa acaaggctga ggaccaaata aaagaagttt tagatatatg taagagatac
    22921 gatttaatgg agaactatgg cagatgtaat tttttaatgg ctaatattaa tttgaaaaaa
    22981 tctaattata atgatgctat agaaaacttt gaaaaggcat tgtacttctt tataaaaaat
    23041 agtgatagtg aaaatatact taagtgttat ttaaacatag ggaaaatata tatgcaggaa
    23101 gacttttata aaggtgctat aagccacttt aattttgcag aggaaatttt gtcagagaat
    23161 aaatttgagg atgttaacat acacaaggaa ctatatagta agatggcata ttgttacata
    23221 aaactagata atccaaatat gtcattgaag tacatagaaa agataaatga aatagataat
    23281 agaaatgata gaaaagaaga tgtcgatatt ttggtgttaa aagcaaataa tatgcttgag
    23341 attggaaaat atgaagaatc aagagattac tttaaaaaag cactaaaaat acttgagagt
    23401 gaggataata aaactggatt agcaaatgtg tatttaacaa tttgtgatgt ttacagaaaa
    23461 ataggtgaaa cagatagagt acttgaatat tcacaaaagg tatatgacat aaagaaaaat
    23521 gatgaagatg aatacatgat gtcaggatta tttaagataa tagaagcata tatagataaa
    23581 gaagattatg atttagctag aaaatattgt aagatagcct tagcttcatc aataaaaaat
    23641 aaaaataaat tcaatgaata taaagcattg agattctatg ctaatatgta taaaaatcag
    23701 aatgaagtaa ctcttgcaat tgaatatctg attaaatgca taaaaatagt atcagattta
    23761 ggcaacaata gaatattggc caatttatat atagacttag gtcaattata ttcaaatata
    23821 tcaaaagaaa aagagttaga atattatcaa aaaggtgtat ttatgtacaa aaatttagaa
    23881 ataatgtagg gtaaataaac ctataagggt atagaaacaa tctataacaa gcaagataat
    23941 atctatgata aaatataaat tgtatgaata tttttaagga gatgaatcag acaatgagta
    24001 taaaaataga tgcgagaggg cttgcttgtc ctaaaccagt tataaataca aaaagagaat
    24061 tggataacct agaagaaggt gttgtagtta caatagtcga taatgaaaca gctaaggaga
    24121 atatattaaa acttgctaaa tctttaagtt gtgaagcaaa tattgttgac gaaaaagaga
    24181 attttatatc tatagaaatt agaaaaggta aaaatatact agataaacaa aatgttgtag
    24241 ataataaaga aagtgaatta gacaatacat gtatatttat atcttcagat aagatgggac
    24301 ttggaaatga cgaattagga aaagtgttaa taaaaggatt tatatataca ttaacagaat
    24361 ctaaacctta tcctaagtat gtacttttag ttaatggagg agtaaaatta agtgctgaaa
    24421 atgaagaaac catagaaaat ctaaaaatac ttgagaatat gggtgtagaa gttttatctt
    24481 gtggtacttg tttagattat tataatttaa aagacaaatt acaagtaggt acagttacaa
    24541 atatgtatac tatagttgag acattaaaga atgcatcaaa taccatttct atataatgta
    24601 tgtttgttta ataatataaa attaataata aagattaact caaatagata gtcagaaagg
    24661 attaagtaat gaatcaaatg tatatagtgt catttaattc gacacatcat gcgataagat
    24721 cagaaaagtt atttggtgaa aatagtctaa aagtaatggc tcttccaaca ccaagagaaa
    24781 taacagcaag ttgtggaata tcaattaaat tttcttttga agatatggaa aagataaaaa
    24841 ctattttagt tgaaaataat gtagatataa aaggaattta ttgtataagt aaattagaaa
    24901 atggctcaaa agaagtagag aagttagatt aggaggctaa ttatttatgc caatggattt
    24961 aaaaataggt gatattgttg aattaaaaaa gcaacatgca tgtgggtgta aagagtttga
    25021 aatcataaga acgggaatgg atataaagat aaaatgtact aaatgttcaa ggctaataat
    25081 gcttgataga gagaccttag aaaagagagt aaaaaagcta ataaaaaagt gataaaaatt
    25141 taacacttaa aaaatgtcaa ataccgtata ttaatatcca aaattttggt ataataagaa
    25201 ttgaagaaaa cattttcatg ggggtgcttt aattatggca gttaaatatg caaaaagaat
    25261 gcaaggatta caaggatcag aaatacgtga gcttttaaaa cttactcaac aaccacaaat
    25321 aatatctttt gctggtggaa tgccggctcc agagttattt ccagttgagg aaatgaaaaa
    25381 agtatcagtt gcagtgcttg aagaaaatgg aagatcagct atgcaatata ctacaacaga
    25441 aggatatgaa ccattaagag aaaaaatagc agctagaatg aatgataaaa acaaaactaa
    25501 tgtaaacaaa gatgatatat tagttacaag tggttctcaa caaggtctag attttgcagg
    25561 aaaagtattt attgatgagg gtgatgtaat tttatgtgaa agtccatctt acataggagc
    25621 tataaacgca tttaaatctt atcaacctaa attcatagat gttccaacag attctgatgg
    25681 aatgataatg gaagaattag aaaagatact agaaacaact gatagaataa aaatgattta
    25741 tgtaatacct gacttccaaa atccaacagg aagaacttgg ccacttgaaa gacgtaaaaa
    25801 attcatggaa atagtaaata aatttgaaat accagtaata gaagataatc catatggaga
    25861 tttaagattt gaaggagaga ctttaccatc tttaaaatca atggatacaa aaggattagt
    25921 aatattctta ggaactttct ctaaaatatt ctgcccagga tacagattag gatggacttg
    25981 tgcttctcca gaaattttat ctaagtttaa ctttgcaaaa caaggtgcag acttacaagc
    26041 atcaactata tctcaaatgg aagtaagcaa atttatggat atgtatgacc tagatgcaca
    26101 tgttgacaaa ataaaagcag tttatgttaa acgtagagat gtaatgctta agactatgga
    26161 agaagagttc ccagaaggat tagtatttac tcatccagaa ggtggattat ttacatgggt
    26221 agagcttcca agtaatttaa atgctaaaga attaatgcca aaatgtttag ataagaatgt
    26281 tgcttatgtt gctggaggag gattcttccc taatggtggt agagaaaata ctttcagact
    26341 taactattca aatatgccag aagaaaaaat aatagaaggt ataaaaaata tagcagctgt
    26401 attaaaagaa gctatgggtg tagaagctta attaaaaata ataacttata tataatacaa
    26461 gggatggttg ttgccatccc ttgtttgttt gaaaagtata taattcacct tatactaaac
    26521 tttgtccaaa atttaaattg acagaaataa gaataaatga taaaatgtgt aggtatgaga
    26581 ttttagtctc atttctctgc tctaagagtg tagagccgtt aagtccaaag ggaggtgaat
    26641 tatagtgaga aattatgaat tagtttatgt ggtaaagcca aactctgatg aagaagtaag
    26701 agaggctata ctaaacaaag ttaaggaagt tgttgcaact gacggagaaa tagttaaagt
    26761 tgatacttgg ggaactaaaa aattagctta tccaatagct aagtttacag aaggtttcta
    26821 tgtattagtt aacttcaaat cagcagtaga cgttcctaaa gagatagaca gaaacttaaa
    26881 gataaatgaa aacgtaataa gacacatgat agttgttgct taataactgg ttttattata
    26941 aaaaataggt ggtgttttta tgaatcaagt tgtattagtg ggaaggttga ctagagaccc
    27001 tgaattaaga tacatcccag gtacaggaac accagtggca tcctttacaa tagccattga
    27061 tagagactat gtaaaaaaag atggatctaa agaaactgat tttatacctg ttgaagtaat
    27121 gggtaaatct gctgaatttt gtgctaacta cataactaaa ggtagattag tagcacttca
    27181 aggatctata agagtagaca attatcagac acaatcaggt gaaaagagaa cttttacaaa
    27241 agtaagtact agatcagtac aagctttgga tagtaagaat aaatcggaaa attcatatag
    27301 agagagtgct ccagcttttg agccaagctt tgaacctcaa ggtttagacc cacaaggttt
    27361 ccaagctata gatgatgacg atataccatt ttaaaaagga gggaaaaaag tcatgatgaa
    27421 taaaaaaaga cgtaagaaaa aaagagtttg tcaattttgt gctgacaaaa acgctaaaat
    27481 agattacaaa agtactcaaa gattacaaaa gtatataact gaaagaggaa agatattacc
    27541 aagaagaata tctggaactt gtgctaagca tcaaagagaa ttaacagttg ctataaaaag
    27601 agcgagaaat atagcacttt taccatatac attagactaa aaaaatgagc cttgtgctca
    27661 ttttttatta tatgtattta tatatctaaa tgaggcgagc tataaagctc gtttttttgt
    27721 ttatatactt aaatatatta ttatttatga tataatatta tatattaagg agggttgtaa
    27781 acgtgaaaat agataaaggt tctgagataa cgagaaacat aaagataata gaatggatga
    27841 aaacagaaat attaatgagt gtaagtgatt tgtttaattt attgtttaaa ggggtaaaac
    27901 cattagatga agcaattcaa gatactttag caaatataat aatgataaca tatctcttag
    27961 caaagagatt aggaattagt tttagagatg tggattataa agtcaaggaa aaaataaaaa
    28021 ttggtataga tgaggaccat agcgttgaaa gatggtatgg agatttatct aatttaaaaa
    28081 aacatatgga taatagggag tgatattaaa ttgaataata aaattagact atctaaggca
    28141 atgtctataa tagttttagc tataataatc gctttagtaa tagcctatat tccaatgcta
    28201 ggaatattta gtatgttagc agctgttcca tatgtaatta taggtgctat tactgataga
    28261 aagtattctc ttatatctat tttggttaca ttttgtgtac tgattctatt tgcagacatt
    28321 tcttatgcat taaatatatg tataatgtat tctttaccag gtatagtaat aggaaagatg
    28381 ctaaagagaa gctttgaaca agaggacagt aataaattcg aaccgatata tggtggaacc
    28441 ataatatttg tactttcaat gcttgtatat ttttttgtat taaagacatt tttaaatgtg
    28501 aatctattag atgaagtttc taagatgata tcagaaattg taaatattca aaaaaatagt
    28561 ttttctgcaa ctgaacttaa agtgtttgat aaaatgaagc cagatgagat tgtaagttat
    28621 tttacaaata tgctaccaat gatgttattt ttacaagggt tgttatcagc gtttgtcaca
    28681 tattatttga gtgtattttt tataaaaagg attacaaaga tgaatataag atttcctaag
    28741 tttgctgatt tttatttacc gggaaatgct atactcacaa ctttcttact ttatttatta
    28801 gtcttattta ttcaaattat tggttcaaaa ttatatacag aattaataat gactaattta
    28861 cagctagttt ttaatttaat gtttgtaatt caaggtatag cagtttgcat ttatttctta
    28921 aagaaatgga taagacaggg accaaataaa attatgtttt tttcagggat aattttatgt
    28981 ttatttggat ttatgggaat atcttttgtt ggtatggtag atagtataat tgactttaga
    29041 aaggtaagaa gctataaatc cacttaggag gatagaaatg agtaataaac aaacctttaa
    29101 attaaatatg ccagaaataa atttatatat aattgttatt ggtatttcta gtataatttt
    29161 gctttattac aacttgtatg tagggtgttt atttttctgt atttttgtat atatggtttt
    29221 tcacaattgg agaactacta atattagacg tcatgaatgg acagagtata ttcaaaattt
    29281 atctttagat atagatgaaa caactaaaaa agccataata aatcttccaa taccattatg
    29341 tattttagaa tttgatggaa atatatcctg gtataatgga aagttttatg atatgattgg
    29401 tcaaaaagat ttacttgata aaaatataga ggatatagtt aaaaatctta atttaagaaa
    29461 agtattaaat gaaaataaag agatgtacac agaaataaac tataaagaaa aagaatatac
    29521 aataatttat aatgttataa aaaatgatca agaaaaaaat cctaaatatt tgatgatatt
    29581 atactggata gacaagactg aatatttaaa agtaaaacaa aattatgatg atgaaaaaaa
    29641 tgcaatgatg ctaatacaag tagatggata tgatgaagta ttaaaaagtg cagcagaaga
    29701 taagagagct ttaattaatg ttgaagtaga gaaaatactt tctgctttag aattaaattc
    29761 aaatggtgca ttgagaagaa cttcaaaaga caaattcttc ttggtaatgc ataaaaaaga
    29821 gttaaaaaaa ttggaagctg agaagttttc tattttagat acaataagac atattgatta
    29881 tggaaataat cttcctgtta ctataagtat aggaattggt atagatggag atacattaaa
    29941 tgagaaccta aaacttgcta cgggtgctct cgatttagca cttggtagag gtggtgacca
    30001 ggctgttgta aaaacaaaag ataaatttgt gttttatgga ggaaaatcta aagctgtaga
    30061 aaagaaaacc aaagtaaaat ccagattaat aggtcatgct ttaagagagg ttatacaaca
    30121 aagtgaccaa gtttatataa tgggacataa atatcctgat atggatgcta tgggagcagc
    30181 agttggtgtt tatgatatat gtaaatcctg taacaaaact gcaaacatag ttttacaatc
    30241 tgtaaatgaa tctatagaaa tatttataaa taaaataaat gaaaataatt actataaaaa
    30301 gttgtttatt ggaaaagagg aagctattga caactgcact aaaaatacat tagttgtagt
    30361 agttgatact catagaccaa attatactga atgtgaagaa ctgttaaagc tatcagagaa
    30421 ggtagtagtt atagaccatc atagaagagg tgtagagttt ataaatgatg cagtgctttt
    30481 attccatgag atatatgtat cctcaacgtg tgaaatggtt acagagttag ttcagtatat
    30541 ggatgaagat gtaacaataa ataaacttac agctgaaggg cttttagcag gtataagtct
    30601 agatactaaa aactttgcat tcaaaacagg tgttagaact tttgaagctg cttcttacct
    30661 tagaaaagtt ggagcagata ctatagaggt aaagaaattc ttcaattctg atgtaaaaga
    30721 tttcataata aaagctgaaa taattcaaag tactaaaata attaataata gaatatgttt
    30781 agcatattca agtactgaga tagatagtat aaatgttata atagctcaaa ctgctgatga
    30841 gttattaaat atcaaagaag tagaagcttc ctttgtatta ggtgaaaaag atgatactat
    30901 atttataagt gcgaggtctt taggacaaat aaatgtacat gtacttatgg aaaaattagg
    30961 aggcggggga cacatagata tagctggagc acagttaaaa aatgtttctc taaaagaagc
    31021 ttataagatg gtaaataaaa taatagagga gtatttggag gaggaagaat agatgaaagt
    31081 tatattatta aaagacgtaa aaggaactgg taaaaaggga gaaatgaaag aagtaagtga
    31141 tggatatgca agaaatttct tatttcctaa aaagatggct gtgcaagcag atagtgtagc
    31201 aataaaagaa ttaaatgaaa agaataaatc taaagaaata aaagcacaaa aagagtatga
    31261 agaagcagtt ttattaggta agcaaatgga agaaattaat atagaaatat attcaaaagc
    31321 aggagaaggt ggaagattat ttggttcaat aacttctaaa gaaattgctg agcaattaaa
    31381 gaaacaaaaa gacatagatg tagataaaag aaaaatatta ttagatgaac caataagatc
    31441 tttaggttca actttcgtag aaataaaaat acatcaaaaa gtaactacta aaataagagt
    31501 ggatgtaaaa gaaaaacagt aataactaga ggtgattaag atggaagata tgacgagaat
    31561 tcctcctcat agtgtagaat cagaacaatc aatattgggt tctatacttc tagataaaga
    31621 tgctataata acggttacag aaactataaa gcctgatgat ttctataaag aggctcacaa
    31681 aataatatat gaatgtatga taactttaag taataaaggt gagcctatag acttgataac
    31741 attaacagaa gaactaagaa aacaagggca tcttaatgat attggaggaa tcagttatat
    31801 tacaagtctt tctactatag taccgacgac ttcaaatgta aaatactatg ctgatatagt
    31861 aaaagaaaag tctgtactta gaaagcttat aaaagcttct aatgaaataa taaatctagg
    31921 atatagtgga gcaactaaga ttgaagatgt tttagaacaa gctgaaaaga gtatatttga
    31981 tatatcacag gagaaaacta gtgatgattt taaatctata aacttagttt tgatggatgc
    32041 ctatgatatg atagaaaaat tatacactaa caagagtgat gtcactggta taactactgg
    32101 ttttaaagat ttaaacaaaa aaataaatgg tcttcaaagg actgatttaa tattaattgc
    32161 agctagacca gcaatgggta aaactgcctt ttctttaaac ttggttcaaa atgcagcctt
    32221 aaaaggtgat gcctctgtag ctgtatttag tttagagatg tctaaggaac aattagtaca
    32281 acgtatgtta tcttcacaat ctagtgtaga attaaaaaaa ataaagactg gaacacttaa
    32341 tgataatgat tggcctagaa ttatagatgc tatggcagta ttatcagatg ccaaaataca
    32401 catagatgat actcctggta taaaaatatc agaactaagg tcaaagtgta gaaagttaaa
    32461 aatagaaaaa ggactagatt tagtgcttat tgattatctt caacttatgg aaggtgaagg
    32521 taataatgaa agcagacaac aagagatatc taagatatca aggtcactaa aaatattagc
    32581 aaaagaatta aactgtcctg tagtagcact atctcagtta tcacgtgcac cagaacaaag
    32641 agcagaccat agacctatgt tatctgattt aagagagtct ggagcaatag aacaggatgc
    32701 agatatagtt atgttcttat acagggacga atattatcat gctgattctg agagtaaaaa
    32761 tataggagaa gtaataatag caaaaaatag acacggtgaa actggttctg tggaacttgt
    32821 ttggcttggt gaagttcaaa gatttgggga taagttgaga gacctataat ctaacgaata
    32881 tccacagaac gtcctttctt tctacaggaa aaatgtggat acatgtcact aaatatgtcc
    32941 aaacattgaa atttagctaa aaaactatcc acactatcca cagatggcct gttgataagt
    33001 gtgaataagt agataaagca agcttttggc ttgctttatc tgtgtataaa tattaattat
    33061 taggaggaat aatatggaaa aaataagctt aaaatatata tatcccaata taattaaagt
    33121 acttgatgaa ataaacttat ttagagtaat tgacaataat ttaagagaat ctattgttgt
    33181 ttatgctaat aatgtggata atcagtatca tataaacatg actaatacaa actttggaaa
    33241 tataattaac atatgtaaat tagaaaaact tttagatgtg gataaattta tggaaaaagt
    33301 tataaaatat gaaaaagaaa taatagagaa agaagagttt tcaaaaatag aagaatatat
    33361 gttaaatatt ggagaatact aaaaaagttg aaaaaaatac gaatgtttga tagaataagt
    33421 aagtaaagtg ttcgagagta tataaaatat agaggtgaat tacatgaaaa cagttgcaat
    33481 tgttggttct caatggggag atgaaggtaa aggtaaagtt atagattatc ttgctactca
    33541 agcagatgta gtagtaagag ggcaaggtgg aaataatgca ggacatacat tagttgtaga
    33601 aggtaaaaaa tacgcattac atctaattcc atctggagtt ttaaatccaa atacagtgaa
    33661 tataatcgga aatggaatag tgtttgaccc taaaggattt ttagaagaat tggaaatgtt
    33721 taaaacggat aatataagta cagaaaatat aaaaataagt gatagagcac atgtcatatt
    33781 cccatatcat aaagaactag atgcattgtc agaagaagcc agaggcgatt taaagatagg
    33841 tacaacaaaa aaaggtattg gaccttgtta tatggataaa acagagagat ctggtattag
    33901 aatatgtgac ttaatggata aagataaatt tgctataaaa ttaaaagctc aaatagatgc
    33961 taaaaatgaa atagttaaaa atatatatgg aaaagaagaa ttatttgatt ttgaaactat
    34021 atataacgaa tatctaggat atgcagagca aataagaaaa tatgtggcag atacgtctgt
    34081 tattgtatat gatgcagtaa gagcaggtaa aaaagtattg tttgaaggag cacaagggac
    34141 tttattagat ttagatttag gaacttatcc atttgttaca tcttctcatc caacatctgg
    34201 tggatttgca attggtgcag gtatagggcc aaatatgata aaagacgttg ttggtatagt
    34261 aaaagcatat actacaagag ttggagaagg accgtttgtt acagagcaaa taaatgaaac
    34321 tggagataag ataagagaac aaggacatga atttggggta actactggta gaccaagaag
    34381 atgtgggtgg tttgatgcag ttatagttaa gtatgcagct agagttaatg gattgactag
    34441 tatttcattt atgttacttg atgtattaac tggatttgat aagataaaag tttgtacgtc
    34501 ttataaaatg ggcgataaga taataacgga tttcccagct tcattagatg atttagcaaa
    34561 atgtgaacct gtatatgaag aattagatgg atggaatgaa gatataactc aaatagataa
    34621 ctttgatgac cttccagaaa atgcaaagaa atatgtagca aaaatagaag aactagttgg
    34681 agtaagtgta gatatggttt ctgttggtcc aaatagagct caaactataa taagaagaaa
    34741 tatatttgct taatatttta tcaattaaat aatttaaaat agttgaagaa gagtatctca
    34801 agataatgtt tatagttatt agagatgctc ttttatattt gacttacatt gattttttat
    34861 taagttaaag ctacttatac atattctaac tgaaattaaa gttgaattta tgtagataca
    34921 tataggtttt ttaaaaagaa ttttgttgaa aataaatggc taaagatgat tttaattata
    34981 ttctaaaaaa agtaaaaaaa actattgact aaaaattata tagacgctat aatataactt
    35041 gtgagtgaaa gaaacgacga aaaaagtcga aaaaatgtgg tctattagct cagtcggtag
    35101 agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc accaaaatat
    35161 ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg cggtaacagg ggttcaattc
    35221 ccctacgagt caccagtatg ggactatagc tcagctggga gagcacctgc cttacaagca
    35281 gggggtcaca ggttcgagcc ctgttagtcc caccaaattt tgaattagag ataaatacta
    35341 gattatatgc tggtgtggct caacggtaga gcagctgact tgtaatcagc aggttgtagg
    35401 ttcgattcct atcaccagct ccacaaagta cataaattca aattaatata attttctatg
    35461 ttacaggata cttttaagta tcttttttta atttcatttt tattgtatta aaaatgaaat
    35521 taaacataca acaaaatttt gaattacttg caatgtgata gttttaaata taaaatttag
    35581 aatcattcta gcataatatt atgtaatata gcaaatttaa tttatagtat caataaatat
    35641 agactactaa gaatgtaaat gatttgttag attaaggtac attagatatg taaatagaaa
    35701 aataaaaagt atgttttaat ttatgtgata taagttttaa acagagaagc aagtttgctc
    35761 ttacctctct atttaaaaat aaaaaaatgt tttttaaggg ctattttatt taaatctttc
    35821 ccatctcaaa tcatctccag taaattctaa aatcctaaac ttatctaata ttctagagag
    35881 agttctttga gtgtaagtat ttcctatttg agatggtgtt aagttggttg aaataatgat
    35941 ttttttacca gcaacaagtc ttgtatttac aatattgaag atttctccac tagtaaaaga
    36001 attattaagt tcagttccaa ggtcatctat tattaataaa tcacaatcaa acaagttttt
    36061 ataattatct tcacttattt gattatttgt gtctcttcta aatttataat cttcaagaat
    36121 atctaaaatt ctaaaagaag tttgatagat tacaacattg cctttatcta acaattcctt
    36181 tgcaatacaa ttgcacatat aggtctttcc tagtccagta gaaccataaa acagtagatt
    36241 ttcactatta tccttcttaa aatcatgaac aaaattttcg cagatactta aattatttag
    36301 catattttct ctaggagata tttcaccatc agagcctttc ttaggagaaa atatattcaa
    36361 gttaaaattc gaaaaatttt cctgacttaa aatcctatct aaattagaca ttttataagc
    36421 ttcatttaca atttcttgtt tgaggcaaga acatttttct ccattaggta aaaatccttt
    36481 atctttacaa gaaatacatt gaaactttat ttccaagtaa tcaagaggta tgttactttc
    36541 agctaaaagt ctttctttct ttacttttaa agattctata ttctctttag tcttctttac
    36601 aatttcatct ttagacttag gatttaaaag tactatctta gctaaactga gacctatttt
    36661 agaaatttca tcatctatag attttatctc agggattcta ttatatacct cattttttct
    36721 atgttctaat aagagttcat tatcatctct tctcttagca tatttagcaa gtatttttct
    36781 tattttatcc tcattcattt aatcacctac ttaaactttt ctttttgact ttttttaata
    36841 atctcatcga gctcatcaga ggtatactga gtgaatgttt cgttgaaatt atgaaactta
    36901 gtttttttgt aagtattgtt gttttgagta gtattaatct gcttcttatt aatattctcc
    36961 ttaactatac gttcttcctc tttttgcttt aaatcattta aattttttat atttttttca
    37021 ttccaatttt taattatacc atttatataa gatatacttg ggtttgaaat attcttagac
    37081 ttagaacatg catttattat caaatctata tccatattaa atttatcaaa ccaggtgtcc
    37141 ataagttctt tttctgattt tgatggttgt cttgaaaatc ccaattcatt gaaaatcgtt
    37201 ttatataaaa tatatcgttc acttcttacc aaaaagcttt cttcaacatc ttttggcgta
    37261 tataaatttg aatcatacca atttctaata atgccttcaa tgtatttaac tggctttgat
    37321 gtaccagttt tatctttgac gtattcatat gcgcaaagta tcatatcggg gctcatattg
    37381 tatttattca ttatatccat aatactcatc ttttcacttg ggtcgagata tcgcccaact
    37441 attttattta tagaattaaa catttttcta atacttggat tttcagaagt agatacaact
    37501 ttatctgtat tagattttat agatgaatta ttgcttaata tattctcaat atagaaattt
    37561 tttaaatcta aaaattctat tgaataatta aaattatcat attcttcatt gtcatgtatt
    37621 tttataatct tcttttcttc ccagaatttc caagcagata acacatcaga caatggtata
    37681 tttaggtttt tggctattga attattgtcg aacttaggat tagaagtaat atcacatgct
    37741 tgtctatatc ctaaaagata aacttttacg tataacccgt ccgccattgg cataaatata
    37801 tctataaaga tattgggaat agtgatttca cctaaatcta tttcattgct ttctttaaaa
    37861 aacattttat cacctcagat taaattatat cattttttat attatatttg tctgtaaaca
    37921 aataaaaggt cacaagatta gcatgtaaat attttctaaa agtattcatt ttgaaaagga
    37981 ggagatattt tggttataaa attcaaccaa aaagtaagaa gaacattatc agtagcgatt
    38041 ctatttatgg tattaataat aggttgcttt atagaaaagg atgacagttt agaaacatac
    38101 aaagaaaaaa ctaattcaaa aataaatcag tataatatgg atgttatatt tgatgatgag
    38161 actaagaggt taatgtgcaa tcagaatgtt gactacataa ataatacaaa atcaaacata
    38221 gataaaatat atttccatat atatccgaat gctttttcca agaaagattt tgctcctttt
    38281 gaaaaaagtg aaatgacaag ggcttatcct aatggattta acgaaggata tatagatata
    38341 aagaatatat taaataataa tagtaaaatg gagtataaaa ttaaaggaga caaaaatgac
    38401 atattagaaa tagaattagg gaaagagtta aaaccaaatg aaagaatgtc attagatata
    38461 aaatataacg taaaaatacc aaattcaatt ggaagatttg gatatggaga aaatactata
    38521 aatgttacta attggtttcc tatagcttgt gtaaatgatg aaaggggatg gaatttaaag
    38581 agttatgaaa ctattggcga cccattttat agtgagacta gcgattttca tgtgaaacta
    38641 ttgattccaa ataaatataa aattgctcat acaggaaaac ttattgatga taaacatgat
    38701 aataagaaaa tgctatatga aatagaagct gaaaacgtta gagattttgc atttatacta
    38761 agtagtaaat ttgatgtaaa caaagtagat tcaaagggag tagctatcaa tacatataat
    38821 ttaaataaaa agctttctaa aaaagcaact gaagtggcaa aagattcaat aaatatattt
    38881 agtgaattat ttggaaagta tccttacaaa gaattttctg ttgtagcaag tgactttttt
    38941 atagggggga tggaataccc tatgcttgtt atgatagacc aaagtttata taatgaaaaa
    39001 aatgaatttt tactagaata tgttattgcc catgagacag cacatcaatg gtggtattct
    39061 gctgttggaa atgatgaaat aagtgaaccc tggttagatg aagcacttac tgaatattct
    39121 acaatagttt attttgaaca aaagtatggt aaagatatgg caaacaagct tataaaaact
    39181 atggagatac agacaaaaag ttatttgagt gaaaatatat ttaagccagc aaatgagtat
    39241 aaaaattcta ctgaatacag cttgaatgtt tatacaaaag gcgcaatagc atttaatgaa
    39301 ataagaaaag aagttggaga taaagtattc tttgagactt taaatgagta ctataataaa
    39361 tataagcata aaaatgctaa tggaagagct tttgtggaac tatggaatag taaaggtgta
    39421 gatataaata agattataag tgaatgtaag taaatagtga atgtaagtaa attttgtgca
    39481 gagtattaaa ttttatttaa tactctgttt ttttggtata atataattta taaggcagaa
    39541 aaagaggtga aggaatgcta aagtattgtt cagtagggag tggtagtagt ggtaattgcc
    39601 actatatagg gtataaaaat actaatatac tagtagatgc aggattaagt ggcaagagaa
    39661 taactacagg tcttaaagac attggtgtag atgcagataa attaaaagga atatttataa
    39721 cacatgagca tgttgaccat ataaaaggag caggtatatt atcaagaaag tttgatatac
    39781 cagtatttgc taatataaaa acatggtgtt ctatgaagga caaattaggt gacatcaaag
    39841 ataaaaatat gaaagtattt gaaaatgata aaacctactc attaggtgat atcatagtaa
    39901 gacctttttc aatagaacat gatgcgtctg acccagttgg atataatttt tatacagaga
    39961 gtgatgaaaa aatgtctata gctactgata taggatgtat aactcaaaat ataaaaaaac
    40021 atctatataa atctaaatta gtagtattgg aatcaaatta tgaccctaat atgcttatga
    40081 tgggttcata tacatatgct ttaaagaaaa gagtaatgtc aagtactggt catttatcca
    40141 atgaagatgc agctaatttc tgcgttgaac ttattaatga aggtacagaa tctatattat
    40201 tagcacattt aagcaaagaa aataattttc ctgagttagc gtatgagact tcaaaaggag
    40261 tattagcatc aaatgatata gtagttggac aagatgtaaa actagatgta ctatcacgaa
    40321 atgatgtttc taatgtttat gagatgaagt agaggtgaat aactttgcta aagagaaatt
    40381 ttgaaaatgt tgaggataat aaaattttat actctataaa gcagggtatg attttagcga
    40441 tacctgctat tatgactggt tcaactgctc ttgtaatttt gaatcttcca ataaaggctt
    40501 atcaagaata tttatcaggc ttgtttaatg gagaggttac aaatattctt aactttataa
    40561 atgattctac tttaggaatt atttcattaa taatattatt aacaataagc tatagttatg
    40621 gaaaaatata tgggagcaag tatacagtac ttgttcctat agttgcaatg tgctcttttt
    40681 tagtattttc acatggtaat gagcttaatt cttatataga aatatttaaa acaaagtggt
    40741 tatttacatc tataattgtt tctatgacat cttctgtatt gtttgtaaaa cttacagaat
    40801 cttttgttac aagtgtaaag tttcatacag aaggggctga tgcagacttt aatatggtag
    40861 tttcggctat agttcctttc ataatagtag tatttttgtt ttctattttt agagtggtaa
    40921 tgataagtct aattggcagt tcaaactttc aagatatatt ttataattta ttttcaaatg
    40981 tttttaataa aatgggaaca aaccttatga gtgctctgtt gtttattttt ttaatgcact
    41041 ttatgtggtt ttttgggatt catggtagta atgtattaga taccgtcgca aaaaatttat
    41101 ttgaaaatag tatggcaatt aacataaatt tagttaataa taatcaatta ccaacagaaa
    41161 tttttactaa gacctttttt gatacaatgg ttttattggg aggatgtggc tctttactat
    41221 gtttagtaat tgcaattttt cttagtgaaa aacgtataaa tgtaagaaag ttagctaaaa
    41281 ttgcttcaat accagctctt tttaatatca atgagatgct agttttcggg ataccaattg
    41341 tttttaacta tattatgttt gtaccttttg taattactcc tataatctta accgttacaa
    41401 gttatgtggc tatgtctaca ggtattgtac catgtacagt ttcagctgta gaatggacct
    41461 cacctatatt tttaagtgga tatatgtcta caggttcaat aagaggtagt ttgttgcaag
    41521 tatttaattt atgtgttggt gttatgattt atattccgtt tataaaaatg tcgcaaaata
    41581 gatatacata tatgtttaaa aataatatag aaaatttaac aaacttatta aaaaggtatg
    41641 aattaacagg tgaacagcct aatcttctaa accataatgg taaaataggt tcaatttcaa
    41701 aaatgttggc atcagacttg aagtttgcta tgaaaagagg agaaatagag cttttttatc
    41761 aaccacaagt caattataat ggaaatgttg tgggagcaga gggattactt agatggaaac
    41821 attcaatagg agggttcatt tatccaccac tagttataat tttggctaaa gaagaagggt
    41881 tcttagatga gcttggagag tatattatta ataaagcatg tattgattta aagaagagtg
    41941 aaaagctatt gagaaatcct gttaagttct ctgtaaatat atctccagac caacttgatg
    42001 accctaagtt accagagcaa ataaaaaata tcattagtag taatgatata aatcctaata
    42061 tgttaggtat agaaataaca gagcaaattg cattatcagg ttcacaaata attattgaac
    42121 gtatcaatgc gatacataac ttgggaataa agttaattat ggatgatttt gggatggggc
    42181 atagctctct tatatatctt caaaataata actttgatat agttaaattg gatggttcat
    42241 tagttaaaga gatacttaca aataaaagaa gtagtgaaat tataatgact attgtaaatc
    42301 tttcaaaaaa tttagatttt gatatagttg ttgagtatgt tgaaaatata gaccaaaggg
    42361 ataagttata tggtttagga tgtgaaatat atcaaggata ttattatagc aaagcaatac
    42421 cttttgaaga gtttgtagaa tatgcaaatc aagaaagaga gatataattt tataagagct
    42481 tgtaaattct agtaatgcat agatttgtaa taaaattaag tttaggagaa atatatgaat
    42541 ataagtatag tagtagtagg taaaattaaa gaaaaatatt taaaattagg tattgatgag
    42601 tttaagaaaa ggctttctaa gtattgtaag ttagaaatta tagagttgga tgatgaaaaa
    42661 gctccagaga atttgagtgt taaggaaatg gaaattataa aagacaaaga aggaaagaaa
    42721 attttaggga agataaagca taatagttat gttatagcct tggctattga tggtaagggt
    42781 ttatcctctg aagagcttgc taagactatg agtgatttag cagttagagg taatagtagt
    42841 ctctgtttta taataggagg ttctttaggg ctttctgatg aggttttagg aagggctgat
    42901 tataggttat ccttttctaa gatgactttt cctcatcaga tgatgagatt gatattgtta
    42961 gaacagattt atagggctta taggataaat aatggagaac cgtatcataa ataaatgata
    43021 cggtttttgt taatttgaca cttaataata ttaaaataac aaaaaagtat tgaaagtata
    43081 ttgcatttaa ggtagaatta aataaaatat tataacatta taatgtttat atggttgtta
    43141 ataaaaattt ggaggaaaat atatgataaa aataatgttg gcctgttcag caggaatgtc
    43201 tacaagttta ttagttacta aaatggaaag tgcagctaaa gaaaatggta tagagtcgca
    43261 aatttgggca ataccagaat caactataca aaatgaaata gaaaaatgtg atgtattatt
    43321 actaggacca caagttagat atgtattacc taaggctcaa gaaattgcta agccatataa
    43381 tataccagta gaagttataa atatgatgca ctatggaaca gttaatggag aagctgtttt
    43441 aaatagagcg atagaactta acaacactaa gtaatataaa ttataatgta tttttaatat
    43501 ataaattggg agaatcaaag gatggatgaa aagactatag aaatatcttt taatataata
    43561 ggttatgcag gtgaaggtaa aggattagct tttgaagcaa taaaagaggc taagaatgga
    43621 aatatagaaa aagcaaaaga attattaaaa gagtctaggg aagttataaa taaagcacat
    43681 agatatcaaa cagaattaat acaaaacgaa gctagtggaa acaggactga aataagtgtc
    43741 atacttatac atgcacagga ccacttaatg aatggcatga attttcaaca gttagctgag
    43801 gaaatcgttg atttacattt gaaattacaa gataaataaa aattaaagat aataaattaa
    43861 gagagttctt aaaagataca ttatgtgtag cacactaatt gttagattat tgattcaata
    43921 tttagtgagt aatacattag gattattttg aggactcttt ttatatttag tttaaagtta
    43981 ataaatattt attattaata atataagatt atatgttata atattataac atataattta
    44041 agaggtgaat catgttaaga aatcaaccat tatatataca agttgtagat atattaaagc
    44101 aaaaaatatt aaataacgaa tataaaattg atgaaaatat tccaacagaa agggagttag
    44161 agcaagagtt tggagtcagt aaaattacta ttagaaaagc tattgagata ttagaatcag
    44221 aaggatatgt agagaaaaaa agtggaaaag ggacaaaagt aataagtaat agccttttta
    44281 ataagctatc aaaagcagag tctttttcaa gtatactttt atctaaaggt cataagttat
    44341 ctaaagagac tatttcaatt gaaaaaataa taaatgatac aaattcacaa gtatttagta
    44401 tatttggaga aaaatgtagc aagattacta gaatgtatta tttagatagt aagccatata
    44461 tattttttac tcattatatt ccttttgatg aaaatctaac tgttgaaagt tttaataatg
    44521 aaagttcttt atatatgtac ttatatagga gaaatataaa tataactaga tttgaagatg
    44581 aattttttat agaagaatca gaactagagg tatcaaaggc tttaaatcta gctaaagaca
    44641 tattattagg aagaaaaaga aagacctatg atgagaatga taatatagtt gagctatcat
    44701 ttgcaagata taatacagaa gtacaaaact atgtaattaa atacgaaata taataagaat
    44761 cctgagttta ttgaaatgat aatatgctca ggatttttgt ttagttgtaa aaataaaaaa
    44821 tattataaca ttataatgtt tacaaccaaa cattataatg ttataatatt tttaataaac
    44881 aagtgatatt atcaattaca taaaaattag tttatgttat gaaatcgtta ttgcattata
    44941 aataaaggat aatatcaata atacaggggg ataactatgg aaaaattcgc aagtttttta
    45001 gagcgcaaga ttatgcctgt agcagcgaag ataagtaatc agagacatat gagagctgta
    45061 agagcaggta taatagcaac attaccacta acaatagtgg ggtcattttt cacaatatta
    45121 ttaaacatac ctattgatgc ttatatggat tttatagctc catttaaagc aatattagat
    45181 ataccattta gatatactgt aggattttta tctctatatg ctacttttgg gatagcatca
    45241 tcacttgcta aaagctacga tttagataca acaggtgttg gtatgcttgc agttatggca
    45301 tttttagttt ctacaatagt tccaactcaa gtagttgaac cagtaggtgg agttatagaa
    45361 gctggtagat ggatggatat ggcaaaactt aattcgccat cattatttgg agctatcgta
    45421 acatcattaa ttacagttga aatatatcgt tttatgaagg aaaagaatat tacaattaag
    45481 atgccagcag gagttccagt agaggtttca aattcattta ctgcattatt accgacagca
    45541 gtaattttaa tgttattctg ggtaataaga catattctag gatttgatat aagtgttgca
    45601 ctaagcgcta tgttatcacc tttaaaagga ttcttatcag gaaatagttt aggtggtggg
    45661 ttactgacag tattcctaat aactttattc tgggtacttg gaatacatgg tccagctata
    45721 atgggaccag taataagacc tatatgggac atgtctatag cagaaaatat aactgcattc
    45781 acagaaggag tatcagctca tgcaatgcca aacatattta cagaacaatt tttacagtgg
    45841 tatgtatgga tagggggagc aggggctact cttgcattag ttgtaatgtt tatgttttct
    45901 aagtcacaat atctaaaaag tttaggtaga ttaggatttt taccagggtt attcaacata
    45961 aatgaaccta taatatttgg agcaccaata gttatgaatc caatactagg gataccattt
    46021 ataattggac ctataataat gacaattcta tcatatgttc ttactattac aggggttata
    46081 cctatgatgg tagcaagatt accatttgca atgccagcac caatagcagc agtaatgagt
    46141 actaactgga gtatactagc aggtatctta gtattaatca actttgtgat atcatttgct
    46201 gtttattatc cattcttcaa agtttttgaa aaacaacaat tacaaagaga acaagaagaa
    46261 atgagtgaaa atttataaaa atacatagat atagaggttt tgtactatat aaaatataga
    46321 aaaagcttat aagttattaa gggtgaaggt aggaggaatg acctttgcct ttaattttat
    46381 atattttaaa taatgtaatt tgaggaggag aaagatggaa agaagattag gaatatcagt
    46441 atatccagag catagtaaca tggaagatga taaggcatat ataaaaatgg cttcaaaata
    46501 cggatttaaa agaatattta tgtgcatgct ttcaattaca agacctaagg aagaagttaa
    46561 aaaacatttt aaagagatta taacctatgc aagagaatta ggatttgaag taatccttga
    46621 tatagctcca aacatatttg atatattaca aatatcttat gatgatttaa cattttttag
    46681 tgagttaaat gctagtggaa taaggcttga ctatggatat gatggaagta aagaagctat
    46741 gatttctttc aatccatatg atttaaaagt ggaactaaat atgagtaatg atgtagcata
    46801 cttggataat ataattactt acaagccaaa tgtaaataat atatatggtt gtcacaattt
    46861 ttatcctcaa aggggtacag gcttgccata tgattttttt gtaagatgtt caaatagatt
    46921 taaaaagtat ggaataagaa ctgctgcttt tgttaattca aaatacgcaa caatagggcc
    46981 ttggaatata aatgatgggc tgtgtacgct tgaaatgcat agaaacttag atattgctac
    47041 agcaaccaag cacttattcg caacaggatt gattgatgat gtaattgtag ggaatgcata
    47101 tgcaagtgaa gatgaattaa aaagaatgtc tgaagtaaat aaatatcaag ttgtatttaa
    47161 tgtagtaact gaagaaaaaa cttctgaagt agaaaagaca ataatggcaa atgagcaaca
    47221 ctttagaaga ggggatataa ccaaccaagt agcaaggtct acagaagtaa gaaaaaaata
    47281 tgctaaagaa aatttcccta agcatgataa tacgaccatc tttaaaagag gagatgtagt
    47341 gattggtaat gatgactttg gaaagtataa aggggaatta cagttgatac ttcaagattg
    47401 tgcagatgaa agaaaaaata aggtgggtag aataaaggaa gacgaaataa tacttttaga
    47461 ctttattgaa ccttggagta aatttaaact tattttagag ggagagtaaa gtgaagatag
    47521 acatattaat aaaatgtgga aaaacagtag ataaaagtat aattgatata gctatattag
    47581 acgataaaat aatagaagta aaaaatcaga tagatgattc taagtatcag gcaaatcaaa
    47641 ttataaacct agatggagaa aaatttatta gtgctggttg gatagatata catacgcact
    47701 gctacgaaag actagacctt tataaggatt atccagatga ggttggaata aaaagcggtg
    47761 ttactactgt agtagatgca ggaacaacag gagctttaga tataggtaaa ttttatgaag
    47821 atactaaaaa atataaaaca aatgtatatg ctttaataaa tattgctaag cagggaataa
    47881 catctcaaga tgaactttca agtatgatga atattgatga atatgaactt agaagagcag
    47941 ttaaaaaata caaagatttt gttgttggaa tcaaagctag aatgagtaaa agtgttgtaa
    48001 tttcaaatga tgttgaacct ttaaaagtag ctaaaagaat aaaaaatgaa cttaatctac
    48061 ctatgatggt tcactttggg agttctcctc caacgataga ggatatattt gactatatgg
    48121 aaaaaggaga tatattaacc catatatata atggaaagcc aaatggaata cttagaggca
    48181 atgaggttaa aaaagaaatc atagaagcta gagaaagagg tataatcctt gatgtaggtc
    48241 atggaaccga aagttttagt atggatattg caatgaaatc taaggatgca ggaatttttc
    48301 cagacactat aagtacagat atatatatta aaaatagaat aaatggtcca gtgtataatc
    48361 tatctacaac aatggaaaag tttatatata tgggctattc acttgaagat ataatagata
    48421 aagttactaa aaatgcagca gatgcaataa gtttaaaaaa taaaggttta ataaaagaag
    48481 gatatgatgc tgatttaact atatttgatg tggttaatga agaaaaagaa cttcaagatt
    48541 ctttgaataa gtcagtaatc acaagtacgt ctataaagcc aagagcagta gtagtcaatg
    48601 gagaatattt aaatataggt aagtctatag gagagaatga gtagaaggga gaaactattg
    48661 tatgagtagt atatttgaaa aatactctgt aagacgtgtt ataaatgctt caggcaaaat
    48721 gactatacta ggagtatcaa cagtagataa ggaagttatt gaagcaatag gtgaagggtg
    48781 taaaaatttc tttataatag aagaacttat aaataaaaca ggtgaatata tagcaaattt
    48841 attagggtgt gaaagtgcac taatagtttc tagtgcatct gctgggattg cacagagtgt
    48901 gggagcaatg atagcaaaag atgatatgag tctagtttac aatgtaaata atcctaagaa
    48961 acaagttaaa agggaaataa taattccaaa gggacataat gttgattatg gagttccagt
    49021 agaagtaatg ataagacttg gaggaggaga agttgttgag gccggttatg ctaatatgtg
    49081 taacaaggaa catataataa gagagataaa tgaaaataca gcagcaatta tgtatattaa
    49141 atctcatcat tgtgttcaaa agagtatgct aagtgtatta gatgcagtac aagttgctaa
    49201 agaatataat ttacctttga tagtagatgc agcagcagaa gaagatttaa atgtatatta
    49261 tgaattggga gcagacctag tgatatacag tggtgctaag gctatagagg gtcctagctc
    49321 agggttagta ataggtaaga aaaaatacat agataatgta aagcttcaat caaagggtat
    49381 aggaagagct atgaaaatag gaaaagaaaa tattgtaggt ctaacatgtg caattgagag
    49441 atatataagt aatgataaag taactttaaa agaaatggag gataagctaa atccatttat
    49501 agacaagata aatactataa agggagtgag tgctagtata actagggatt cagcaggtag
    49561 agaaatactt cgtggagaaa ttgactttaa tgaagatata ataaataagt caacacaaca
    49621 aattataaat gaacttagaa gtggagagat agctatatac actagagact ataaggctaa
    49681 tgaaggcaag attgagattg atataagaag tgtaactgga agtgatttag atactattta
    49741 taataggata aaaaatatag tagaaagtta gagtgtagag taagtgacat tataatgatt
    49801 taataaatta aattttacca atggagggga taaatatgaa ttgtatacca caatattata
    49861 aaaatagagt ttgtttaaat gttcttgcag gaagcataaa aaatgctaaa gaagtatatg
    49921 atgcttgtga cgggcatgta ttgataggaa tactatcaaa gaattatagc actgtagaag
    49981 cagctattga agatatgaaa aaatactcaa aggaaataga taatgcaata tctgtggggc
    50041 ttggagctgg agacccaaat cagtcaaata tggtatctca gatttctaaa gaacttcagc
    50101 cacaacatat aaatcaagtg tttacaggtg tggctacgtc tagagcattg cttggtcaaa
    50161 atgatagtat aataaatgga ttagtttctc caactggtaa accaggattt gtaaaaatat
    50221 ccacaggtcc attaagttca aaagaaaaag atggtatagt tcctatagaa acagcaatag
    50281 ctatgatgaa agatatggga ggaagctcaa ttaagttttt tccaatggga gggcttaaaa
    50341 caaaggatga atatatagaa gttgcaaaag cttgtgcaaa gcataatttt tatttagaac
    50401 caacaggggg tatagactta gataacttca aagagatagt tcaaattgca cttgatgctg
    50461 gtgtagaaaa agttatacct catgtttata catcaataat tgataaagaa acaggtgaaa
    50521 cgaaagtgga agatatagga gtactttata aaataatgaa agaattattg ggatagattt
    50581 atgaatatat tagcttttgg tgaaataatg atgagacttt cagtacctga ctacaagttc
    50641 ttaacacaaa ccaatgaact aaattatata actacaggca cgggattaaa tatattatct
    50701 ggacttaaaa actttggata caatacctat atgttgacaa agttgcctaa taataatgta
    50761 ggtaaagcat caagtgcaaa tataagaaag cttggagtaa aagatgactt tatcacgtat
    50821 ggagggaatc atataggagt gtattttctt gaaaatgggt atggagaaag accttctgaa
    50881 gtgacttatt tgaataggtt aaatagttca ttttgtgaga gtaaattaca agattatgat
    50941 attgataaat gtttagaaga aatggatata gtccatattt gtggtattgc tatgcaactt
    51001 acagattcag ttaaagagat tgctttagaa ctagctagaa aatcttatga aaaggggata
    51061 aaagtattct ttgattttaa ttttagacaa tcattaaatc cagaaaggac ttatgatgat
    51121 ttagtaaatg attataagaa aatactacca tattgtcatg ggctgtttgc tagttataga
    51181 gatataaata agatacttaa tatagatagt ctaaatataa aatctagttc agaattgatt
    51241 aaaaaagagt atgatataga tattgtagct ggaactatga gaagatttga tgatatgaat
    51301 aatagattta taaagggata tatatcaaat gatgatggtt attttgaaag tagggagtat
    51361 aagctagaaa tatatgacag ggttggtgcc ggagatggat atgtagcagg aattatatat
    51421 tcatatttgg aaaatatgaa gagtgaagat atagttgagt ttggggttgc tagttcggtg
    51481 ttagctcata caacttatgg ggataattct ttagtaagca caggtcatgt acttagactg
    51541 atgaataatg aaaaaataga tatattgaga taatacattt gtatataata aaatttttat
    51601 cttttttaga cacatttttg acttgcttat atttgttaaa cagagttatt tttaatgatt
    51661 ataaatatta aattaaaagt taaataataa aatagtagaa aatagcatta actatagaaa
    51721 aaatggttaa tgctattttt atcgttaata ttgattaatt ttatattata gaaatgaact
    51781 tttctaatgc tggatttgta ttttttttat tccatacaac tacaacttca attctatttt
    51841 ctacttcttt tataggtact attgcaatat cacgttctat cattgtatct gtaacacaaa
    51901 atgaaggtaa aatggatatt cccatgttag aagataccaa tgattcaata gtattaagat
    51961 tatttgaacg ttgtaccaca ttaggtacaa accctgcttc acgatatcta ttctgtatca
    52021 ttgacttttg tccatactca tcccctgttt cctttacaaa aataaattta tcatgttgta
    52081 attcaattaa atcgatagaa tcctcattgt aaagtggatg accaggaggt aaaagagcta
    52141 ccaaagaata tctttctaca gttttatatt caaaatcttt taatggttga ttttctggat
    52201 taataacaaa agcgaggtcc atagaattat tttttactaa gtttaaaagt tcggttattt
    52261 cattagtaca aatatccata gatatattag ggtatgtatt agaaaattct tttaaatatt
    52321 gttgaagttt gtttttttca tatcctatta aggttccaat gctcaaagtt ccaaaaaaac
    52381 catgtgcaaa ttgttgtgtt tttgcaatag catcattgat attttttatt atagtacgtg
    52441 cctcagataa aaaaactttt ccagctggtg ttagttcaac atgacgttta cttcttgtaa
    52501 atagagttac atttatttgt tcttctaaag cttttatttg ctgtgtaaca gcagtttgag
    52561 aaatataaaa tttttctgct gttttggtaa aacttagatt ttctgctaca gatataaaat
    52621 attctaattg tttagtattc aaataatcac ccctatttaa acttgattgt ttgtaaacct
    52681 tatttatcta taattaaagc ttattatagt ataagaaaat ttacttttaa agaatattag
    52741 aaaatatttg tataaaaata tatgttttaa gtatatcttt acattagatt ttataaattt
    52801 attaataaga ataacttata tattccaatg aaaacgatat tggatttaag taagtttgtc
    52861 tcataaaatg aaagtatatc aattgataat actttaaata agaagggaga aaaaatggaa
    52921 gataaatttt atgcaaaagg caacggaaat aacggatata ttaaaaatct tgaagtttgt
    52981 tcctttaata acttagatgg aacttgtgga atgtttcaaa tggctctgta caaaagagat
    53041 gaaaaatact atttatatgg atgctgtttt ggaggaaata aaaaaaatgg agtaatgatt
    53101 agcgatatta cagaccctta taatccacaa tttataaaac attttcaaat gttagaccct
    53161 aaagagtatc ctacaacaac aactcccaaa attcaaatag cagatgattt aatgatagta
    53221 gcaatgagtt gtggaagtgg accaggagca cttgttgacc aagctaaatt agcaaatatt
    53281 aagtgtgaag caggaattag aatatatagt ttaaaagaag accctttaaa tcctaagttt
    53341 ttaggatatt gggattgtgg cttaaagcat gtaatgggtg ttcatagatt catgtacaat
    53401 ggtggaagat atgtacattt atcaagtgat tgtgttggct ttgaaggtct gatttatagg
    53461 gtcatagata taataaatcc tactaatcca gtggaaatag gtaaatggtg gagaccagac
    53521 caatatgcaa atggatatcc aaatagaact tttgatgcag gagcacctca ttgcccagaa
    53581 tttatggata aaggatggct tcatggacct ccatttgtaa gagacggaaa agcatattgt
    53641 ggttatggag gagctggttt agttgtatta gatgttgaag atttaacaag accaagatgc
    53701 ttaggtgaat tgccatttat gcctgcattt tctagtagac ttgcaggtgc aagaactcat
    53761 acagcattac cattgccagg aagagattta gtcgttgttc aaaatgaggg agaaagattc
    53821 cagttcttta aaccagataa cattacagat gttcaagcta tgaataatat acatatggtt
    53881 gatgttagtg acccaacaaa accaacatta attgctcaat ttccatatcc tgaagttcca
    53941 aaagatttcc cttatcctaa ctttaatgtt gcgggattag gaaaaccagg gccatttggc
    54001 ccacataatc ttcatgaacc aatggataat aagccatggt tagagcaaag aggagataga
    54061 gtatattgct gttatttcca tgcagggcta agggtttatg atgtatcaga cccatattat
    54121 atcaaagagc tagcatattt tataccacca aatccaaata aaacaccaga agaatcttat
    54181 ttcccaggat tcccaggacc acgcttggca gtaacagaag atcttatcgt tgatgataga
    54241 ggctacatca tcatagatgc tttagatgat ggattctata tattaaaaat gaaagaagat
    54301 taaataaata ctaaagaggg agagttgaaa atgaaaatac taggtatttc ttttggaaca
    54361 aaaaatggaa ataatgacac aatgtgtaaa gttgcactta aaggtgccaa agaagcaggg
    54421 gctgaagtag aatttattca aatgtcatct attaacatta aacattgtac tggatgttgt
    54481 gcgtgtgtta aaactttatt atctgggaaa ggtagtatgt gtgtattaaa agatgatttt
    54541 gaatggttgc ttgacaaaat gaaagatgca gatggtatag tagtttcaga ccctattttt
    54601 gaagaagggg catcaggatt attccatact ataatggacc gttttggacc cagagcagat
    54661 agaggaaata acattatagg aacaaaagtt gcagaagcta taggaggaaa aattccagat
    54721 tcaagaatgc ttaatgataa agtaatatca tttatgggaa taggaggttc tgactggggt
    54781 acaagagttc aatgtgaaca tgctatgcta gctctcatac caatgtggaa agttatagat
    54841 aatgcttggt tcccatgggc aaaggaatta gtaatggatg atacaaggct tgttcaagtt
    54901 catcaaattg gtttaaatat agttgaagca gcaaaagatt ttgaaaaagc ttcatatcaa
    54961 ggagaagaag gtgtatgtcc acattgccac aatagattat tctaccttga gccaggtact
    55021 aaaaaggcaa tttgtgctct atgtggtata gttggagagt tagatactat aagtggaaaa
    55081 actatattta gttttccaga agagcaatta ggtcatgctc atgatacttt accaggtaag
    55141 tttatacatg gtgatgatat taagaaaatg gaaggtcatt atgcagaagt tcgtaaaaca
    55201 caagaattta aagaaagaaa aacatcttat aattttatag agccattaac taaagaaaag
    55261 caagctggag tttcattagg ataataatta aaatactaag actctttttt aaggtatgtt
    55321 agatgttata ggaggcttat tgtatgaatg aaaagtcaag ttttaaacaa attgaaatta
    55381 ttttagcagt tatttttttg gtacttacat attacaaggt tagattaact ccagcattta
    55441 ttgttatatt tataccacta tatttaagtt attttgcagt atctatgatt gtaaatcaaa
    55501 tagcaattaa gctattggag ataaggcaag ctagggaagc tactaattac aatataggaa
    55561 atggatagaa agaaaaaaga aatattaaca ctgtctatgg ggattgcttt actacctcct
    55621 ttatgggcag tattagcacc ttatatagga ataaaaactg gagctgtagc actaatctgt
    55681 gcaggattat atgtaactaa tggtaataaa caaaaagatg gattaaaaat aatgtttggt
    55741 ttttggtgtg gagatttatg ggcagtgtta gccattttaa ttatgggata tatgaatttc
    55801 aatcaaaacc tagaattatt tttaacactt agtatattag gtttttttgc agttgtaatt
    55861 gcatccttat ttgaaaaaat aattttccta ccatcatggc tttgtggttg ggctataggt
    55921 ctaactatta tgacaggtga aaatattatt aatttacaag atatttgtat tcaaattgct
    55981 gtagctatgg cagtaggagt atggtacgtg ggtgcaggtg tagatttgtt tacaatatat
    56041 attttgagta aagataggaa aaagggaaat tgaaagcatg tgaatatact ttgattatag
    56101 gagaatggct atgggttttg aatttaaaat aatgagaagt ttaatatatg taggacttgc
    56161 caaggaagaa tatagaccta agctaatgga ctggttatat cgtcaccata ttccagatag
    56221 tattagcact tttggaccat attgtactaa atatgccttt tatcaagcat atcctacacc
    56281 aaatgaaggt gagcgttttg gtgcacgtaa gatgcaacta acagaacatt attggcttgt
    56341 agatgaacat atgcctgaga tggcaaatag aattatgaca gaatatatgc ctatggatgt
    56401 tctacgttgg caagggtgta taccagatgt agaaaataaa agggttcatg aaaatgcaga
    56461 aagtggagat gcaggacgtg cagtaggtgg agataatgga tgtccaccat ttatatttgc
    56521 ctttgttcca ataaactggg aagaagactt tagaggaaaa ggacgtactg tacaagatgg
    56581 accaaactat cgttggcaat ttatgattaa gtatccagat ggtatctcta aagaagaagg
    56641 agaaaaatgg ttctatgatg aggtagtgcc atactttaca aactgttgct atgttaatcg
    56701 ttttgtcagt agtaaaataa tgattaatta tggagcaact gcttttgacc gtgtatcaga
    56761 actatggttt gaaggggaag aagaatggta taaagctgtg gttgaagaga caaagtcgtt
    56821 tattaaaaaa ccagaatggg cacaagaaga ggagttccca tatttaaaac cacaattcaa
    56881 tatcgcatca gtattcttag gtgatatagc aactatggat gcatactcac agtatcgtgg
    56941 atatatacca atgagataaa aattatagtt tgtgataagt agaggaggca tttactctta
    57001 ctggtagaag aagacttatt gtatccttaa aagtaggtga atatatagtt ttatatttaa
    57061 atttatataa aactaagact aataaatatg aaacaataga attagaataa tttgataata
    57121 tttgttaaaa gagcatttag aatgtgttta aagattaaga tattcctttt atggtagcag
    57181 atagttgaaa taataaaact gttatcatga aaggaatatt tttatgtata ggaaattttt
    57241 aaaaataaaa gttaaatatg tttaagaaca tcttaaagtg aaagaatcat tgttagaaat
    57301 atgtagacaa tatagtcttt ataacgtatc atattaacaa gtttacactt ggattatgaa
    57361 ataaaaagag taattccaaa ggttgtaaat actatgctga ctttgatact tcaaagttta
    57421 ggtgattttg taattgttaa tagaaatacg tttaatgagc ataaagaatt tatctaataa
    57481 taggagaata taatgtatac aattggacaa gtatctaaat ttttaggaat atctagagat
    57541 acactaaaat tttatgagga caaaggatta gtaaatccta agaaaaatga tgaaaatgga
    57601 tatagaatat ataatcaggt tgatatctat gatattgcaa caataaactt ttatagagaa
    57661 attgatatag aaattaaaaa gattcaagaa ataagaaaaa gtaagagtat aaacaattta
    57721 gaactcttac tagaagagaa ggaacaaatc atactaaaag agatagaata taaaaagctt
    57781 ctcttaaaaa aggttcagtt agtcaaagaa gattgtgaca aaataaaaac atattttgga
    57841 aaatacacaa taaaagaaat gaagcctttg gaagtaaaag gtaaaataaa acatgttact
    57901 aactatgagg aatatgaagc cttaaaagag aatacaaaca acttaaaaaa agcagttaca
    57961 ttaactgatt taagaagagt aataaatttt aatgaagaag gtataataga agaaaaattt
    58021 ataattgtaa gggaagtaga tgactacaac aaaatcatag aaggtgaagt tctatctcat
    58081 cccaattgta tttatactat tattgaagat ggcagatggt caactggagg agaaaatatt
    58141 gataataaag tggaagacag attaagagaa atagcaatag aaaatgaatg tgaattactt
    58201 ggaatagtct atgttaatat attgcttact acttatgaag aagggattga gcgtatattt
    58261 ttagagattt atgcacctat aaaataatat aaaagcattg acctgggact tactcatagg
    58321 tttaaactca tgatataagc agttataact tatatagcaa ttaaatatta atttgaaatg
    58381 aggattactt atgagaacag agaaatcatt aaaaaggcct atagccagtt ttattattct
    58441 aacaaatata atttttttac cacttttttt attggtagta gtgactataa tgttaaaact
    58501 tccaacagtg atatctgaca ttgcgttgtg tatatcagcg tggtcatcca cttttgcatt
    58561 tatgatatta tttaaaaaaa tttatccagg taagaaattt ttagtacacg taaaagatag
    58621 atttagaaat aaacttaaat tttcaacagt atctataata attagtatac aagtcctaat
    58681 agctgtagta gttatattta tattagcatc taaaaatcat ggaataatgc ctaactttac
    58741 agtttcatca tggggagcat ttatatattt atttttaaaa aatttatttg caggatcatt
    58801 aggtgaggaa ttaggttgga gaggatttgt tcaaaatcat cttcagaaaa gacattctcc
    58861 tttaaaagca tccataatag taggtttttg gtgggggatg tggcatttac caatatggtt
    58921 tacaacagga ttcaaaggac ttgatttaat aaaatatatt atatttttta tgattgcaat
    58981 tatatcaatc agtattataa tgacaacttt ttataatcta aataaaactt tgataatacc
    59041 tattgtaata catcaactat ttaatttttt aatagggata attaatggag atttaataga
    59101 gcttataaat tactatgcaa tgttatattt aatatttgca attgcattaa tagttataaa
    59161 tccaggaaat gtattatata aaaatattag agagtaatat atatctttat ggtaagatat
    59221 aaagatatta ttagaagaac atccaaggag gaataaacat ggttttactg attgttgatg
    59281 cacaaaagtt aataacaaac gagaggttat ataaatttaa tgaatttgta gtaaatgtag
    59341 aaaatttaat tgatacagct agaaaaaata atatagaagt aatatatgta cgtcatgatg
    59401 atggagttga aaatgaattg actaaaggta aaaatggctt tgaaatatac gaaaaattta
    59461 aaccatgtaa tggagaaaaa atatttgata aaaaagtaaa tagtgctttt aaagaaactg
    59521 gtctattaga atacctaaca aataatggtg aaaaagatat tattattgct ggtctccaaa
    59581 cagattattg tattgatgcc actataaaat gtggatttga acatggattt aatataatag
    59641 ttccagctta ttcaaataca actgttgaca atttttttat gtcagcagaa caatcatata
    59701 aatactacaa tgaatttata tggaatgaaa gatatgcgaa gtgtatttca ttagaggaaa
    59761 cacttagaaa aatgaaataa aaatagagta tgaattgtat atgtacataa gttgatttca
    59821 taaaaaagga tgttaaattc caagttaaaa attagattaa atatattata ttatagataa
    59881 ggcacatcaa ttttatttta aattaatgtg ctttttaatt gtagtaattt atttataatc
    59941 aatatgattt ttattattta aatcaatttt tcttgagttt ctttgtctaa agaaactttt
    60001 tttatttata aaatctacag ttatattata gtatctattt tagagaagtt taatttttgt
    60061 atcaatctaa aacaaaagtt atacttaaat gaaattgaaa acgataaaat tctcaaataa
    60121 aataagtatt gtggaggtga tgaaagaatc caatgataat atgaagacta atcttaataa
    60181 gaaagtaggg gttaatggta gtggacaaag aaattgtatc aattctccag attttattaa
    60241 atagcacatt gattacaact aatggattac aagaggagtc taattcatca aagagacaaa
    60301 ttacttatag aataaataaa atcaatgaca tgcttaaagt aaaaaatgta ccacttatat
    60361 gtttaagagc tgataaagat attatcgtta gaaaagaaac aaaaaaagca attaaagaaa
    60421 ttttagaaaa aaactattct aagaatactt attattttag taagacagaa agacttttat
    60481 atatgtattt aatgcttttt attaacatgg atgatatttc aattaatcat tttataaatt
    60541 ctataaaagt aagtaggtct actgtaaatc ttgatttcaa ggatttgata ccagagcttg
    60601 aaaagaagaa cattaaagtt aagaacaatc gtataaatgg atattacata gttggcaatg
    60661 agatggaaat taggagagtg cttattaaaa atattataga aactttgtct aatgagaaaa
    60721 gttcaagagt atttgatatt tttattaaag aatataattt agatagtttt gaagaggcta
    60781 aaaaaattat attaaagcta ataaaaaaat atgaaattac ttttgttgaa gatagattag
    60841 tagaatttat atatatattt atctttctaa aggcaaggat gtattcaact agaatagtta
    60901 ctcaggaaaa tgtagatatt cctaatattt cagttatgag ttcaatgaag gagtataaat
    60961 ttgctaagga attattagaa gtatatggga gtgaagataa gataaagcct cacaatataa
    61021 tgtatattag tgcttggatt ttaggtatat cagtaggaaa ttatgaagaa gatacagaag
    61081 ataaggatgt aatttcaaaa attgtaaata aaatgatgac aaagtttgga tatttaagcg
    61141 gagtttacta tataagccaa gaaaaaatat ttaaacaatt atattctcat tttagacctg
    61201 cctactatag acttttattt aaattaccta tttataatcc gatttgtgaa aaagtaaaag
    61261 aagaatataa attagtttat agaattgtaa gtaatgcaat gaaagagttt tgcggattat
    61321 ttggagaaga aattcaggaa gaagagttag catatcttac aatgcacttt gcaacacttt
    61381 tttcaaataa aaaagaattt gatggtttta gaaaaagaat agcattaata gtttgttcaa
    61441 atggcgttgg tagttcagct attttacatg cagaacttac aaacttattt cctgacttac
    61501 actttatacc aatgtcggaa tcagttggat tagaaaatat aagtgaacct gtagatattg
    61561 tatttactac taattataac gcagagggtt taaaaacaga tgtaccagta attaaagtaa
    61621 gccctgttat gaccacaaaa gaaaaatata agattacacg tgaagtgtat attcaattag
    61681 gtgatatttt tttaagacaa cctaaaatag atgaggttat ggatataata aaaaaatatg
    61741 caaatgtaac ctctgaaagt attctttcaa gtgagctatt agcttatttt acacagatag
    61801 agaattttac atctaaggaa ggagaggggc ctatgctaag tgagattact aatgaaacac
    61861 tagtaaaaat aaaggtaaaa gctaagaatt gggaggaagc tattagacag tcagcttctg
    61921 tattagttga aaataacaaa gtaactgaag ggtatgtaga tgctatgatt aactcagcaa
    61981 aagcatctgg accatacata gtaattacaa aacatgttgc acttccacat gctagaccag
    62041 aagctgggtc aaaagagatt gcaataggca ttgctacttt agatagtcct attgagtttg
    62101 ggaataacga aaacgaccct gtaaaatatg tattttgtct aagtgcaata gacaataata
    62161 gccatttacg tgctatgtct gagctagttg aactattgga agaagatgag ttttttaagg
    62221 ttttagatag tgctaaagaa gctaaagaaa ttattgattt tataaaaaca cacgaattat
    62281 aaaggaggat ttaattatgt ataaaatttt aatcgcatgt agagcaggag ttggctcaag
    62341 tttaatgtta aaaataaaga ctcaacaaat tattaaggaa aataactttc caattgaagt
    62401 agaacatggt tcattggatt cactaaatgg attcaatgga gatgctgtag aaacattaat
    62461 tgatgttgct gaagaattaa aaaataaaaa tttgaagttt gatataattg ggattcacaa
    62521 tattgttgac cgtaatgaaa taaagacagc actagaaaaa ttccttgctt caaaagaggg
    62581 ataaatttaa gatgataagg aggaatattt atggagttta ttattagttt gctgagtaca
    62641 cctgctgttt tgcttggcgt agttgcatgt ataggattga ttcttcaaaa gaaatcagct
    62701 gttgaagtat ttacaggctc ttcaaaaaca cttatcggtt ttttgatatt tggtattggt
    62761 gcctctgcta tgacaggagc acttcaaaat ttcaataaac tgttccaaca tggctttgga
    62821 attactggtg ttatagcttc accagaagca gctacagcac ttgcacaagg tacatatggt
    62881 tttgcagttt catgtacatt aattcttgga ttcatattaa atttagtatt tgcacgtatt
    62941 acaaagttta agaatatttt ctttacaaca ggtcatagtt tgttcttttc ttgtgtatta
    63001 gttttaatta tgaaagcaca tggatttgat aatacaatca ctattttaat aggtggaact
    63061 atcttagggt ttatgtctgc tgcactacct caattctgtc aaccatttat gcgtgaatta
    63121 acaggtggcg acgaacaagc tattggtcac tttaacatga ttggttatgg tttatcaggt
    63181 tatattgggc gtttattttc aaaacataaa gatgatacaa cagagactat agaatttcct
    63241 aagtggttat caatattcag agacttctta atgggtctat ccatagttat gttaatctta
    63301 ttttatattg caacattaaa agctggtcaa gcatttactc aagaaattgc tggttcaaca
    63361 cattggttgg tttttccgct tatagaggca tttacatttg tggcaggtat gtcaatattg
    63421 atgtcaggag ttcgtatgtt cttagctgaa ataactgcag catttgtaat catttcagaa
    63481 aagtatattc caggttcacg tcctgcgcta gatgttccaa ccgtatttcc atatgcacca
    63541 aatgcagtta ttattgggtt tatatcagca tatgctgctg gtctattagc aattgctatt
    63601 atggcatcat ttcctagtat atttcctgta gtaattattc cagctgctca catatgtttc
    63661 ttctcaggag gtacagctgc aatatttggc aatacttcag gaggatggag aggggctatt
    63721 gctgggtcat ttgttgtggg gttattactt gcatttttac cagttatact atatccagtt
    63781 tatgggactc ttggtataga aggagcaact ttccctaata ttgattacaa cgtagttggt
    63841 tcgatattac ataatatttt acaatttata aaacctattt agactaaatt atataaaagt
    63901 atagtcatag ttactatgat ttcaaggagg atacatctta tggaaaatac attatctgaa
    63961 tttttagata atatatctaa tgaattgtca gaatttattg cctcaataga tgagacatct
    64021 ataaataaag catgcgaatt aattcttgaa gctgaaaaaa atcacggacg tgtacatgtg
    64081 actggtattg gcaaaccagg acatgtatcg ggatatattt catcattgct ttcatctact
    64141 ggaacgtcag catatatatt gcatggtaca gaagcagtac atgggtcaag tggtcaagta
    64201 gttgaaggag atgttgttat tgcaatatca aatagtggtg aaactcaaga gttaaaagca
    64261 actcttaaga ctctaaaagt aaatggagca aagataattg gtgtaagtgg taatgagagt
    64321 tcatttttaa aaaatatttc tgatatattc ctgtttgcag gtgttaagca ggaaggagat
    64381 tgtctcaata aagctcctcg tgcttcaatt ttagctgaaa caataatatt acaatcatta
    64441 agtgttgtat tacaatatgc taaaggtctt aatacacagg agtatttgaa gtggcatcca
    64501 gcaggaagtc ttggaaagtc tattagagag ggaatataat tttatgaaat ataaagggat
    64561 tatatgtgca atgataacac catttgatga aaatcaaaat attaattcac aagcaacatg
    64621 tcaattaatt gattatttga ttgaaaaggg aatttatgga ttatttattt tgggcactaa
    64681 tggtgaatgt catgtattaa cagatgatga aaaagttgaa tttgcaaaga ttgttattaa
    64741 tcatacaaat aatcgtgtac ctgtttttgt tggaacaggg ggtaattcaa ctcgtgaagt
    64801 tgtagattta tctaagagaa tggaagcgat tggagcaagt gcattatcta ttattacacc
    64861 atactttgtt acaccaacac aacaggaatt aatcttacat tacaaaacta ttgctaattc
    64921 agttaattta cctattataa tgtataatat gccaggtaag actggaatta atattgaacc
    64981 agagtcagta cgtgaattat caaagataaa gaatattgtt ggaattaagg atagtagtgg
    65041 taaacttgac aacatgaaag cttatattga agcaacgaag aatgagaatt ttagtgtgtt
    65101 ttcaggctca gattcactta ttctggatag tctaaaagct ggtagccaag gagctgttgc
    65161 agcaacaaca aacttcctca cagagattgg tatctctatc tatgaaaact ttatgaaagg
    65221 ggatttggaa gaagctcaaa aatctcaaag tagtatagaa gaacttcgac gtatactgaa
    65281 acttggaaca attccatctg ttatgaagaa aactattgtc ttgaatggaa ttaatgttgg
    65341 aactgcacga cttcctgtaa ctgaaccaac tggggaagta cttgaagaaa ttaaacgagt
    65401 agttgaaaat tataggacaa tacttaataa aagtagtgag aatagataat ataaataggg
    65461 aaattacact ggtatataat taatatatat attataaaac atgactaaaa ttaatgaata
    65521 agtaaagtgg tttgatgagt atagaggtga taatatgaaa aagatgaata taaccaaaag
    65581 aatgtcagaa tgtggggctc ttgcaattgt aagagaagaa aatcttaacc gtgcatgtga
    65641 aattgctgaa ggatgtataa aaggtggtat aacagttata gaaatgagtt ataccctaaa
    65701 taatgctgga gaaataattc aagggcttaa taaaaagtat ggtgaaatac tttgtgtggg
    65761 agcaggaaca gttttggata gtgaaacagc tcgtcatgct atattacatg gagcccaatt
    65821 tattattgca ccaaattata atgaaggtgt agcgaagatt tgcaatagat atcagattcc
    65881 ttatgctcca ggatgtacat cattgactga ggcagtagac gcactaagtt taggagcaac
    65941 ttttataaaa gctttcccaa tatcagattt ctatggacct aaactagtaa aggtatttaa
    66001 gacaccaata cctgatatgc cagttttagc aagtggaggg cttaatattg aaaacctaca
    66061 tatatggtta gaaaatggag ttgatgtatg tggatttggt ggtttattaa ctaaaggttc
    66121 tgttgaagat attgctaaaa atgctaacaa gattcgtgaa atcattaaaa atgtaagaaa
    66181 aatttaacat agggctgtat catagtatct tataattact atgatacagc ctttttaata
    66241 ttattcaaat ttaaaacagt ttacatttct attatattac atataatttc agtaatttta
    66301 tcttaatttt tctatctgga aaaaaatgat ttaaaactta agttatgata taatttcatt
    66361 aaaagaaggc gatttttagt aaatatgaga aaataatgtg tttttagggg aaaagttaaa
    66421 tacagattta agtgaacaag aatcgataat taagatatta aatggtgaat agggcatcaa
    66481 aaaaattact aaattaaaag ttttagaggg agaatcttag caagtgtgtg tgaaaattca
    66541 atttcaaaca aaaataattg taaatgaaat caatttatac acgttgaaga ttcactttta
    66601 tcattatatt aaaaagcaga gtgaattaaa agtgagtcta aagataggag gataattaaa
    66661 acaatgaaag aagacattag gttacatcga atgtgtaaaa aagaacaagc aacaaagaat
    66721 gaagttatat cagaggatat tctaaaatct atgagtattg gggtcagtaa acatttttta
    66781 gatgattcat ttacaataat atggggaaat acatcattct atcaattatt aggatataca
    66841 gaagaagaat ttttagttaa attttctagt ttaaaagatt attatgaaca gaatctttat
    66901 cattttgaat ctatgaaaaa tcatttttta gaggcttatc atcatggcga aaagagtata
    66961 gaatatcaaa tttgcatttc agcaaataat ggagaccctg tttgggtaat aatgactggt
    67021 atattaattg aatcacaaga taatgagaaa tcaatggtct atatattgta ttcaaaaatt
    67081 aatgagttaa aaataaagca agaagaacta tctgatatgg aaaaagagag tacagagaat
    67141 tttaaatgga tgatgtcaga gtatgctggg aatgtttata ttagcgatat ggatacatat
    67201 gaattactat acttaaataa gcactcatgc aatactttac aggcatcagc aaatgaactt
    67261 attggaagaa aatgttatga ggtaattcaa ggtagaactt cgccatgtcc gttttgtaca
    67321 aattcgtatt taaaaaaaga tgacatatat gaatgggaat tttataataa aaaactgaaa
    67381 cgaacattta taattaaaga ccgtatgttg aattggcaag ggcgaagagt tcgtattgaa
    67441 ttatcttatg atatgtatag tgctgaatat aaattagcaa aaaaagatca ggaaagagaa
    67501 tcaattttga aaactattcc agcaggaatg gttagattag atgcaagaga ttatcttact
    67561 atactttggt gtaatgatat atttttgaat atgattgaat atacaaagga acagtttgca
    67621 gaggaactta ataatcaatg tggatattta ttttctgaag attataaacg tagtaagaaa
    67681 ctggcacaag atttgaagga gtctggggat aatgttgtat ttgaagcaaa aatatataca
    67741 cgttcaaggg aagaacgtat atggactgtt acattgtgtt atatcagtgg ggaagacagt
    67801 tgggatggaa taccatcttt ttatagtata ggtattgaca taacaaagga aagaaaacag
    67861 attgagaaat tacagcatat atcagagaaa gatgcattaa caggaattta taatcgtgct
    67921 gagactgaaa ggcagattaa gaaatatttt gaaaaaaatt taaatgttat gggtgcactg
    67981 tttatgattg atacagataa ttttaaacag attaatgata cagaagggca tatgattgga
    68041 gatatagtac ttactgagat ggcatcaggt atgaaaaaaa taatgcgtga cagtgatgtt
    68101 gttggaagaa taggtggaga tgagtttaca atttttatga agaatatttc ctcagttaaa
    68161 gatgcagaaa agaaagcaga agaactattg tatatgttcc gtcatctatt tcagaaagaa
    68221 aaaagttttc taaaagtaac ttgtagcata ggaatagcta tatatccaaa ggatggtact
    68281 acattcaagg aaatatatgc aagagctgat aaagccctgt atcaagcaaa aaatatggga
    68341 aaaaataatt atgtaatcta caaccaagat tattttaaag aattagaaga atttgattgt
    68401 tcttctcttg gtacagttat tgattcagaa aaacaatacg ctgaatatcc tgataatctt
    68461 acacgttata tattccgtat gctttatcag actgatgata tagaccaggc gattaatatg
    68521 atacttgagg ttgttgggaa acagtttgat gtaagtcgtg tttatatttt tgaaaataca
    68581 gaagatggta gatatacttc taatacttat gaatggtgta atgaaggaat ctcttctcaa
    68641 atggcttatt tgcaaaacag caattatcaa gactatgagg attatgaaaa gctttttgag
    68701 gatgaattag ttttttattg tcgagatatc catacattaa gtcctaaact agaagaattg
    68761 ttttctagtc aaggtatcca ctctacactt caatgtgcat ataaagaaga tagagttttc
    68821 agtggatttg ttggatttga tgaatgcaca ggactacgtc tatggtcaca agaggaaata
    68881 agtacattat cattgatttc tcaaattata tcaatgtttt tacaacgtaa aaaaaataat
    68941 aaacttaatc aacagattca acaataccag aatattttag ataatattga ccagtgtatt
    69001 tgtgtgatta ataaagaaaa taatttttta ttatatgtaa ataaaaaatt taaaaataca
    69061 tattctaaat tccaaattgg acaaccttat tatcttgatt ctatagatat tcataagata
    69121 tccattatat ggaataaaaa agaagcatac ctatgtacta gcacgattta atggtaaagt
    69181 aaagtttata ttggacttaa attaaatttc gttttaaata agatattatt ttagttgctt
    69241 actgaaaaga ctagaatcta tattaatgaa ttatactaat tttataccac tattaaaata
    69301 ttgtttgcta aaaataaaaa atagccttaa aacagttgat tataaaaaat taactgcttt
    69361 aaggctattt ttatctttgt gacgaaatag acacttgcca tttagaatgt gacaatatag
    69421 tagttgttta gaaaaggcac aaagcattat actttaacta aagtaaaatg tattttgctt
    69481 ttagaataaa aacaattagg agggagctat aattgaaaaa gataatatat gtattattta
    69541 caattgaact attaatagta tctttattag gtctaaatat agttaaagat aatgaaatta
    69601 ataatatttt atataacgat acaacaagta tatctgtaat gtttaaagat tataaaaagt
    69661 taaataaaaa ttatagtaag tggattaaag atattgcaga tgaaaataat gtggctatat
    69721 caaagtatgt ttttaataat aatgaaaaat tatctatata tacgactgat acaagtttga
    69781 ataacaatat aaagttaaaa tcaggaaaat ttcctaatac taattcaaat gaatttatta
    69841 gtaatataaa cactaataat agtaatcaag taggtaaatt ctcaactatg agtaaagaca
    69901 tatcaatttt aattagggat tttggtaaaa taagtgaagt tggagaatca ggaatcttat
    69961 atatttcaac tcaaaatgaa gatacaataa ataaaatatt aagagaacta aatgtagaca
    70021 gaagtatttt tgtagcaaga ttacatgata gatatgttaa ctcaaattta tacttaaatc
    70081 cttcaataat tagagattta atactaatta tcctttgttt cttggctaca ataatacatt
    70141 attcaattag tgtgagtaga gaggcttcta ttttaagatt aaatggatac tctaagctag
    70201 atataattgc tagagttata aaaaatatac ttagaattat gattttatca tctgtcacag
    70261 cattattaat atatataatc tatattttaa aattaaatat aggtgttaga gcatgcttat
    70321 actttgctat gttttcgatt atatgtattt tgataaatat tttgatatct atattaatag
    70381 ttggttttaa tagtagaagt tctaaatatg tgctatctct aaatggaaaa aaatcttatg
    70441 gttttgtaaa tataatgcat ttcacattga aaattgtatt tgtatcattt cttatattat
    70501 ccataaataa ctgtatttta aattataata tgctacaaac tcagttagga aatctatctg
    70561 agtgggataa agcaaaaaat gtttataatc ttactcttaa agatacaggc gaacaatctt
    70621 taggaaagga agaagtaatt aaaaatgcca agattaaagg tttctataaa aatttggtag
    70681 aagaaaaaga tgctttctta atagattcaa ctaattttga aaaacttgaa gatggaagtt
    70741 acatgtatga aataaattca aagggtaaaa acccagaagt aagtcaatat ggtaaaaata
    70801 taaaaataaa taaaaactat cttaaagtta accctattta ctcaaatggc aaagaaatat
    70861 ttaatctaat cgattatgac gataagacta taaatttatt agttcctaaa aagttacaag
    70921 tacatgaaaa tgagattaaa aaagagttta gagaattatt ttattttgaa aaaatagaag
    70981 tagaaaatat gtacaataaa gagttaaata gagagttaaa taaaacaaag aagtccgatt
    71041 taaatgttaa tataatatat gtagataata atcaaagcta ttttacttat aactcccttg
    71101 ttatggatga caataggaat ctcattgatg acccaatagc aatagttgac atagataata
    71161 ttgatgattc tttttatctt tcttatatat ctagatgtgt atattttaat tctaagaaat
    71221 tagatgccct tgcagatata agtagcatta ttgaagctca aggtgtagaa gcgcatatcc
    71281 aaagtttaca tgctgtttat aatgagtatg gtttagaaat aaataaacta gaaaaatatt
    71341 tgaatagtga aatttttact ataataataa tagcaatatc aaacttaatg attacctaca
    71401 atatagtagc tagctactat gaaagaaata aatataagtt atatattaaa aaaatatttg
    71461 gttactcaac tacagctaga agtatgttgt taatagtctc attaatatta acaaacatta
    71521 ttccaatagg cattatatca acaagagtag atttaagtaa taatattatc ttatttggac
    71581 ttctaatatt agttatagaa gtaattgtat ctattgtatt agacaagatt atctcaaata
    71641 gttcatttaa taaaattata aaaggagaac attaaaaaga tgatttcatt aataaatata
    71701 tctaaaaaat ttaaagataa atctataata gacaaattta acctagaaat ttctaagggc
    71761 gagtttgtag cgataacagg aaatagtggt tcaggtaaga caactttact taatataatg
    71821 ggattattag aaaaacctaa ttctggtgat attataataa ataatataaa aaatccaaat
    71881 agtaaacaga taagaatttt acaaagggat ttttatggct atctatttca aaattatgct
    71941 ttaattgaga atgaaaatgt tgaaaataac ttgaaaattg ctttaaagta tcaaaaaaat
    72001 atcaatcata atgaaaaaat aaattacgca cttgagtctg taggtcttag aaaatacaat
    72061 aaaaaaaaga tatacgaatt gagtggagga gaacaacaaa gggtagcatt agcaagagta
    72121 atattaaaag aatgtgaagt aatatttgca gatgaaccta caggtaattt agataaaaaa
    72181 aatagagaca tagtatttga tatacttaaa agtctaaata agaatggtaa aactatcgta
    72241 tttgtaactc atgatttaga tttatcggag caggcagata gagttataaa attgtaataa
    72301 tataaactat aataaatata agaaagagat tacagctaaa ttaagtttaa taataatacg
    72361 aatagaattt aaacattaag taaattagta gtttgtaaat ataagtataa tatgatatca
    72421 taaaggctca aaagaaattt tatataataa gaaatctaaa aataacaaat ggaggacata
    72481 taaagatgga aaatttacca aattgcccga aatgtaattc agaatatact tatgaagatg
    72541 gaactctttt agtttgtcca gaatgctctc atgagtgggc attaggattg ggagctgaag
    72601 aagattcaaa tattatcaaa gatgtaaatg gaaatgtatt aaatgatgga gattctgtta
    72661 cagtaattag agaccttaaa gtaaaaggaa gttcatcatc tataaagatt ggaacaaaag
    72721 tgaaaaatat ccgtttaatc catgactcat cagatggaca tgatatagaa tgtaagatag
    72781 atggttttgg agctatgaag ctaaagtctt ctgttgttaa aaaagcgtaa tattataaat
    72841 aagctgtagt gtttattgtt tttcagtaca gtataaaacc ataagaatct attaagtaat
    72901 aaaagtttgt ttatttatct ttatattttc ttatggtttt attaaatata aattttattg
    72961 aacaccaaaa tattctctcc tctacaaata agccaatctt atttaaacta atatactttg
    73021 tactatttat actgaaattg taaatttaaa tgctatgtta tttaggtttg tatagttaat
    73081 ttatatattt ctgattttat aaattgtatt tattattata tcttgattct aaaatcatta
    73141 aaaatttcaa cttctataaa gatttacaat ttatcaaata cattatgagt atataaacaa
    73201 tttattatta cagtgctaca tttaaaataa gtcttagtat aaaggtattg ttacaagtat
    73261 aaagaaactt atgtatgcta ttggaataaa taatacctta aattataatt aagaataaga
    73321 actgttaaat aagggacttg attatcattt agttatagat aatataatat taaaaataaa
    73381 gtttaagagg agaaaaaata tgatagatat acataaaaat atatatgata ataagttatt
    73441 tgaggagcta aagattgact gtaagaagtg ctttggactt tgctgtgtag ctctttattt
    73501 ttctgcttca gatggatttc ctatcaataa ggaatcagga aaaccctgta ttaatttaca
    73561 accagatttt aaatgttctg tacataatag tcttattaag cgaggtttta aagggtgtac
    73621 tgcatatgat tgttttggtt caggtcaaaa agtagcacaa gtaacatata aggggataga
    73681 ctggatgcaa tcaccagaac taacaaatca aatgtctgaa gtgtttttaa ttatgagaca
    73741 attacatgaa atgttatggt atcttaaaga agcatctgta ttaaatatat cagatacaat
    73801 caaatcaaaa attgatttaa taattgaaga aactgaaaag ataactaata tgggcccaga
    73861 acagataatt aatttggata tcatatcaca tagaacaaag gttaatttat tattatcaca
    73921 agcgagtgag tctatgatgg gaaaggttaa atcatttatc aagacttcta ctcttaaaaa
    73981 catgaaaaaa ttaagtaaaa atatagattt aataggagca gaccttagaa aaataaatct
    74041 aataggagca gatttaagag gtagatttct aatagcagca aatttaagaa atacagattt
    74101 gagtggggca aatttaatag gagcagactt aagagattgt gatattagag gtgctaatct
    74161 tgaaaatagt atatttttaa cacaattaca agtaaatact gcaaaaggag attctagtac
    74221 gaagttacca gcttcactaa tacgccctaa atactgggaa aaataattaa attaatacat
    74281 aattttacaa aatatgaact tttttgactt taattcatat tatacattag agattcttta
    74341 caagaatttc ttaatataat atagggagag atataaaaat gagttatcaa aattataaat
    74401 gtgaaagaga ttatgtgtat gatgattata aatacaataa gtgcaacaag tgctataatg
    74461 attatgagga aatgacacat gttcatgaat attcagaaag tgttaagtta gcagaagaat
    74521 gtgaggatag acataaccac cgtgcagcag gggttactgg tgaagttata ccaataaatg
    74581 gaggtacaaa tcatgttcat aaaataaatg ataatgtaga tttccttgac catttccata
    74641 agatatgtgt tacaacaggg ccagcaatta gaatacctgg aactgataaa cacattcact
    74701 taatatgtgg agaaactact gttaatgatg gtcattgtca taaattcctt tttactactc
    74761 aaatagaagc acctttagta taagctgatg tgaattattg tagtgaattt gctagattat
    74821 agtataatat ataatagata atatttaaac ttaatgagga ctatgatatt taaccttcgt
    74881 agtcctttct aagttttgta taaaaaagtg ttatgcaatt aaaagtgata tagggaggaa
    74941 atttttatga aatctggaat aattcttgaa atgaaacaaa taaattcaac agaatatgac
    75001 gaaatgttgc aagtctggga atcatcagta agagcaacgc atgatttttt aacagaaaaa
    75061 gatattgaat ctttgatacc attagttgag attggactta aagaagtaga aaatatagtt
    75121 tgtataaaag ataatgatat aataaagggc tttataggaa tagataaaga taaaattgag
    75181 atgctcttta tagaagataa atatagagga aatggtattg gtaaaaaatt aataaaatat
    75241 gctatagata aatacaatgt aaaatatgtt gatgtaaatg agcagaataa aaaagctgta
    75301 ggattttata ttcacttagg atttaaagtg tttgataggt ctgaaataga tggacaaggg
    75361 aacccatttc caatactaca tatgaaatta atttaaagtt atacttccca cttattcgca
    75421 aaaatattta cttaaatttt tatacaaata aaagtcgtga cagtcttagg acacgacttt
    75481 tttactacac tattaaattg aaatttatct gttctatatt atgattatta gatgtagttt
    75541 ttttatttta actatgtact taaataccaa gtatacccat acctatcaag tacttcagca
    75601 gcgccatcat tttgatgtgg tggtgggtgt ggtaaaaatt cttgtacaag tgtaccacct
    75661 tcggcaagtt ttacagatat ttcttctatc gcttctcgag atggtagaac aacacaaatc
    75721 gccatgccag aaattacaac aggcttgtct gtatccgcac ccattataca accttcgtat
    75781 tttgtgaaag taacacttgc gtgcataata ggattgtttg gattgctgtc taatcgcgca
    75841 aatatagttt ttcctcctcc gaaagcctca gcataaaaat taaatgcttt ttcacaagta
    75901 ccattaaata ttaaatatgg agttagcatg accaatatat cctccttgat atagaataat
    75961 ttatagttgc acctgataat ctaaattatg atttagtaaa ttgtatcata gggaaacctt
    76021 gaagtatata attttttatt attatattat acaaatttat taatttaaaa aaatgttata
    76081 tgtacggaag gtttacagga taaaatataa taaaaagatt aaggtgacat tataaaaaat
    76141 gtatattgac attgacgcta cgtaattgta tatactttgt cttaaaggag atggtaaata
    76201 tgaatattat agaaattcgc tcagataaaa tatacaagaa gataatggat gcaccaataa
    76261 acaaaaaaga agatatatac agatatgaat taatgaagcc ttttgaattt aagtggaagt
    76321 gtatgaatgt tccaatagtt gctagacaga aaggtggata tgatgtaatt atagcaagtg
    76381 aaatgttagg ggttttatcg cctaaggata ttgatgaaaa gcaaaaaaag aatataaatg
    76441 tgttatctgc tgataaaatt tggggcactt gcaaagaaac catagaaaac tctataaatg
    76501 cttttataaa agaagggtat gatttaaaca ttaaggacta taaatattca atattattgg
    76561 cgaatccaaa tagtccttat acaatattaa gtgatggata ctggggtgat ggtgggattc
    76621 ctggatatat atttctatca ttggttccta atgaatatac tatcaataga ttaccagtat
    76681 taatagcaca tgaatgtaat cacaatatta gatttcagtt tatagagtgg aataataata
    76741 taacattaga agaaatgatg ataaatgaag gtcttgcaga aaattttgca acatggatgt
    76801 ttggagagga aatgttagga ccttgggtca gtagaacaga tatcgaaaca ttaaatactt
    76861 atataaagcc aataataaaa agtgctttaa aagaaactgg atttcaaaat ataacatctt
    76921 atctttatgg tgatgatata gctaaaatgc aaggatattt tccagtaggg ttgccttatt
    76981 gtgcaggata tgcttgtgga tattatatga ttaagtatta tttagaaaag acaaataaat
    77041 caataatcga agcgacttta ttgccttata gtgagataat cgaagcagta aaagagtttt
    77101 gggaataaat tttataaatt gcataatttg aaataaatta tgcaattatt ttatttttaa
    77161 gaaaaaataa attgacaata atttataaga aatatacaat aatatatata aagaaatatt
    77221 tcaatattta aaagttttaa gatttcatat ctagagtagc taacattaca tgttagtttc
    77281 ttgttactta tctaattact ttatatttcg tagttatata taaaattact ataaaaaatg
    77341 aaatatatta aacaatcaac tgaaaaatga aatgttaata aaaaaaaatt caaattataa
    77401 atattaaatg aatataatta aaacaaatat ataaatttaa gtataacact cacattttaa
    77461 tgtattgtga aatttttgtt gaactttatg taccataact tataaaattt atgtcatgtt
    77521 atatttgaat aagtaataaa attgtagatg taaattaatc tacaaaattt atatgaaatg
    77581 gagttgatgc tatgacagaa ttaatgatta taagtgggtt agtactattg atttgtataa
    77641 cttctagcaa ggtattgtat aaatttggag taccaatatt attgattttt atcttactag
    77701 ggatgttatt tgggtctgat gggatggtag gaatctattt tgataactat gaactgacaa
    77761 aacaattatg ttctattgga ctaatattta taatgttttt tggagggttt ggaacaaact
    77821 ggaatatggc taaacctgtt gctatacctt ctatattaat gtcttcactg ggtgtaataa
    77881 ttacggctgg ggttacaggt atgttttgcc acatggtaat aggaactagt ttacttgaag
    77941 gtttattaat tggggcaatt gcagcttcaa cagatgctgc atctgtgttt gctgtgttgc
    78001 gttctcaaaa actaaactta aagggttcac ttgcatcatt attagaagtt gaaagtggaa
    78061 gtaatgaccc aatagcgtat atgctgacac taattctttt gacattgatg aataattctg
    78121 gggtagaact tattgcacca atggtaataa aacaaatagc ttttgggtta gctataggat
    78181 ttatactagc aaaattatct gtttatattt taagacattc aaacttcgag atagaaggat
    78241 tttatactat atttataaca gctattgcaa tactttctta tgcatttagc gagtatcttg
    78301 gaggaaatgg atatttaagt gtttacattt caggtattat tataggaaat agtaggatac
    78361 ctcttaaaaa aagtttggtt catttctttg atggaatttc atggattatg caaataatgt
    78421 tattctttat gttaggattg ttatctttcc cttctaagtt accaaatgta tttggtatag
    78481 caatggccat atctatattc atgatagtta ttgcaagacc attagcaaca tttatagttc
    78541 tagcaaaatt taaattctca aataaagaaa aattattcat atcgtgggta ggtcttagag
    78601 gtgcggcttc agtagttttt gcaatttatg ctgttactca aggagtagcc atagagaatg
    78661 acatattcca tataatattt tttatagcgt tgctttcagt aggaatacaa ggttcattga
    78721 taccaactgt agccagaaag ttggatttag ttgatgataa tacacctgta ttaaaaacat
    78781 ttaatgatta tgatggagaa attagctcta aacttatcga agtaaatgtt gatgagggta
    78841 ataaatgggc taataagagt ataatagatt ctaatatacc agacgatata ttaatagtta
    78901 tgataaaaag aaaggaacag gttttaatac ctaaaggttc aaccattata aaaacagggg
    78961 atattttggt attgagtgga gatagaattg aagaattaat acaattataa tttattttgt
    79021 attgacttta acctaagggg aaagtttaaa cttaaattaa tcaaatctaa tgcgcaggtg
    79081 atgagatgtt ttctatagga atgttttcta aaataaataa aataactaca aagacattaa
    79141 ggtattatga agatataggg ttgttaaaac cagaatatgt agatgaattt acaaaatata
    79201 ggtattatac aacagagcaa ttacctaaat tacatcagat aataacttta aaacaaatgg
    79261 gtttatcatt agctgagata aaaaaagctg tagaaaatcc tgaagaagtt gaaaatattt
    79321 taatgaataa agaaaaagaa atgttggatg taattaaaag tgaagaatat aaaataatta
    79381 aactacgtaa ttaccttatg aatttgaaag gagaagtcaa tatgaatgat gtaattatta
    79441 agtctttacc aaaagttaaa gttgcttcta tgagaaaagt gttaaagggg tatgatgaac
    79501 tttttaatct atttccaaat gtaatggctg aagaaatgat gaaaacaggg tgtacatgtg
    79561 cagttcctga ttattgtttt aatatatatc atgatggtga atatagagag actgatatgg
    79621 atgttgaaat gtgtcaagct ataaatgatt taaaggaaga tacggatata ttaaaattta
    79681 aagaattaga tgcagttgaa aatgcagttt gtatattaca caatggtcca tattcaacat
    79741 taggaaaaac ttacgcagat gcatttaaat ggatagagga taataaatat aaagtggttg
    79801 gaaatcctag agaatcttat atagatggta tatggaataa agagagtgaa gaagactggt
    79861 tgacagaagt tcagatacca gtgaaacgca tgttataata tgtctacaaa gtataaataa
    79921 gaataaaaaa ggtggtgtct caaagtaaac attttagttt atgagacact ctttttcata
    79981 tgaaatcaag tatattttta taattacgat tatgaaaaaa ggcttatcta tatttttaga
    80041 cagcctctta tttttttatt ataatagttt tctaaagatg ctctatttat aaatttttat
    80101 taaagacttt ataaataatt gtatttaata tacaaaatat atataaatat tgatgtttta
    80161 tatataaagt tgtatatttt tttaaggata taaagtaaaa aaatatacaa tatcaagaaa
    80221 aaaagatatt gggtatttaa agtaatactt tatttaattt taagtaaatc gggtatctac
    80281 atatatagat actaatttca aagaatagga gggtgtttat atggaaatat tcgcaatagg
    80341 acattcaaat tatccatatg ataagcttat taatatgata aaaaaatatg acataaattg
    80401 tgtagttgac attagagaaa ctccatattc taaatataat attcaataca ataaagaggc
    80461 atttaacgaa tctcttagaa attccggatt tttatatata tacatgggaa aagaatttgg
    80521 agctaaaaga actaataaag atgtatatac gcaagaaggt tatgcagatt ttgagaaagt
    80581 agcaaaagaa gatatttttt taaacggaat agaaagatta aaaaagggtt gtcaaatggg
    80641 ttataggata gttttattag gagctatgca agaacctata agatgtcata gaagtatctt
    80701 ggtgggaaaa gtattaaata aagaaggttt tgatgtaaaa tatataatgc atgaaggaaa
    80761 tttggcatat caggaagata tagaggaatc attattggat aagtatttta gtgatagaaa
    80821 gcaactgagt attgacaatt tattagggag tgcattaacg agagaagaaa tgatacaaga
    80881 aggttataag ctagctaata aagaaatagg atatagaact gagaaactag gtaaataaaa
    80941 atatacaaat agataaaata cagtacttat cttaagtaaa ataatattat gaatttataa
    81001 tagctaggca tgatgtgcca attaaaaata ttctagttat ttaataatat cattaaattt
    81061 agggtatttt ttaatagcac atcatgttgc agttttaaaa aataaaatct ctaatattgc
    81121 cataatcaac tgttctatta agagtaggat gactagatat aaatctaact gtaatttttg
    81181 aatttaacaa acaaggattt gaaattaaaa atactctatc tccattgaca atagaagtaa
    81241 tagctactgg caaaatatct acaaatgtat catatctgtt tttagcaatt tgataaggat
    81301 aatttcctac aaaaacaaat agatttaaat catatatatt atcagtaaac caagcccatt
    81361 gaccataaac tttgtcaata ttcattgtgc ctaaaccaag tgtatcaaag tatgttgcta
    81421 tagttaaata aatattttcc atgttttcta aatatgaaac agtatatctt ctgaaacgta
    81481 tgggtgctgt ggaagaaata ggataaacca tatttacatt tagattattt gcatttaaat
    81541 taaccaaagt atcacatcct aaaattagtc tataaaatac aatatttaaa tggatgcgat
    81601 tttgttacat ctaaagtgta atattttata tattgaaaaa gtggtaaaag tttggatgat
    81661 taaataatat tataaaaaat atataaaatg tacttattgt tattgctaca cgatagtgat
    81721 acaatattaa cgaaatatag ctacttttaa taataacgga aaatatttat attaaattaa
    81781 taaatatttt aaatgtggta tccataaaaa ataataaaca taagataatt ataaagatat
    81841 actgtgttca aatgatatta aacaagattt atattatttg aaagcagtat attataatgc
    81901 gaacaataca attctaaact ttgcattgtc aatttacagt tcgataaact aattaaaaat
    81961 taaatttata taaagaggga aaagaggaat agggatgttt ataaggaaaa atgttataaa
    82021 gttagcaatt cctataatga tagagcagac gtttgtcatg cttttaggag tatttaatac
    82081 aatgatggca ggtcatattg gggaagaagc tgtatctgca gttggaatgg ttgattcaat
    82141 aaacaatata tttatatctg tatttgctgc actatctgtt ggagctactg ttgttgtagc
    82201 tcaacaaata ggaaaaaaag atagtgaaaa ggtgaatgaa actattaagc aggctctagt
    82261 gtctggagta atattatcct ttacaataac aatattgatg tgggttttta gaactggtgt
    82321 aattaattta ttttatggtt ccgcagaaga attggtaaaa tcaaatgcaa aattatacat
    82381 agagtttaca ttatttacgt atccatttat tgcgacacaa caaatagcaa atggtatttt
    82441 aagagggtgt ggagatgtaa agaaacctat gtatgtgact atgtttatga atatagtaaa
    82501 tgtaacattg ggatatatac ttatatatgg tattgattta aatcctctag gaataaattt
    82561 gcaaacacca tcctatggca taacaggtgc agctatatct attgctatag ctagaataat
    82621 tggatgtata gtaattataa gagctttatt taaaggaaac gaatttatat ctatgggtaa
    82681 aatatttcca tttaagattg atgttgaaac tcaaaagtct atatttaata taggaatacc
    82741 agctggagtt gaacaactac tttttaatgc aggtaaattg attgttcaag tatttatagt
    82801 tactatggga acatcagcaa ttgcatccaa tgcaatagga atgtcaattg catccataat
    82861 aaatgtaatt gggaatgctt tagctttgtc tgctacaacc ttggtgggac agtatatagg
    82921 acgtggagat attaaaggag ctaagagtac tttattatat ttaactaaat ttgcaacaat
    82981 ttgtttattt atagtaggag ctatatttat accaattgca ccctggattt caagtatgta
    83041 tactcaaaat gctagtgtaa ttgacatctc aacacaatta attcgaagtg attgtttagc
    83101 tatggtaata tggcctatat cctttgtatt atcagcaggg ctaaagggag ccggtgatac
    83161 tagatataca atgatgactg cagtaatagg tatgtggatt tttagaattt ttacaggtta
    83221 cgtattgggg gttgtattag aatttggagt gttaggaatt tggataggta tgtatactga
    83281 ttggcttgtt agagggactt tatattgttt aagattaaga ggaacaaagt ggctaaaaca
    83341 caaagttgca tagaatatat gaaatcactt ttagatggat aactctattt agaagtgatt
    83401 ttttatgtag ttattatcat aattataagt atgatatata aggtgattaa attacataaa
    83461 taaaggctat aatagtatgg atattataaa ttatatattg agcagaatta cataatttgg
    83521 cgataaatat tagaaatata tatctataga aaataatata tatgggtata ttattaaata
    83581 taaaaaatat taggtattta tttaataata aaggtgggta ttgttatgat aaataaaata
    83641 ggaaaaataa ctctctatgt aaataatcaa gaggatgcaa agttattttg gacagaaaaa
    83701 ttgaactttg tagtaactta tgaaaaggaa atgggtccaa atatgaaatg ggtggaagta
    83761 gcaccaagta aaaatgaatt tacaacattt gtgttgtatg ataaaaatct aatgatgaag
    83821 caaaacaaag agataaatgt atctcatcca tcaataattt taagtacaag agatattaat
    83881 ggaacttatg aacaaatggc aaataacgag gttgaggttg gggaattaat ggagatgcca
    83941 tatggaagga tgttttcttt taaagaccaa gatggaaatg attatttggt cagagaggat
    84001 aaataatttt acaaagtatt aaatttactc aatatctgat ataattagag acaataatta
    84061 ttataaacta gtctaggatt agaattatat aattaaaaat taagtgtaaa ttttgagtag
    84121 aggtgataaa atgtttaaga aaatggcagt actaaaagat atagcaacta aaataggtcg
    84181 taaaaaagcg tatgaactat tagaaatggt tgaaggtaat gatgcctttg tagctgaggt
    84241 aaagataaaa aagaatggaa tagaatctaa aaaagaagaa attatgttaa aagataatca
    84301 aaaaataata ttagagtata tagaaggtta aattttaaat acatataagt tgatatacta
    84361 aatttctgag atgagtttac ataaaactca tcttttttac ttttcaataa ctttgtttta
    84421 ttatttaata tacattttat ctccttagag ttgctgatat ataaaaatta ctgatataat
    84481 aaaagaatgg atattaatgt aatattttat agaaaagagg ggtattatgc ttgaaataaa
    84541 aaatctttcc tttaatgttg agtctaacaa tgaggaacta ggaataataa atgatgttag
    84601 cctttcattt gagaggggaa aacttattgt tatcacaggt ccaaatggtg gaggaaaatc
    84661 tacaattgct aagcttatta tgggaattga aaaagctacg agtggtcaga taattttaga
    84721 tggagaagat ataacaaatc ttagtattac agaaagagca aaaaaaggaa taggatacgc
    84781 atttcaacaa ccaccaagaa taaaaggtat gacagttgaa aatttactta cacttgctca
    84841 tggaaaacca ttgtctactg atgtatgttg ccaatacctt acagatgttg gattgtgttc
    84901 aaaagactat ttaaatcgtg aagttgataa ctctctttct ggaggggaaa tgaaaagaat
    84961 tgagatagca actctttttg ctagagattt aaaggtttct atatttgatg aacctgaagc
    85021 agggatagac ctttggagct ttggaaaact caatgaaagt tttaagaaaa tacatgaaga
    85081 gtctaatcag actataatca taatttctca ccaagaaaga atattagagt tagctgatga
    85141 aataattgtt ctacaagatg gttcagtaaa aagccatgga acaaaagagg ctatattacc
    85201 tgaaatcatg tgtcaagtta attcaagttg tgaattaatg aaagacatga attaattaga
    85261 aaggaaggca aattaaatga acaaaataga tttaaatctt ttagaaaaag ttgctgaact
    85321 tcgtggaact ccattaggag catacaatat acgtaaaaat gggcaaggag tagagagaca
    85381 ttcaactgaa aatgtaacta taattcctaa aactgataaa cctggaatag atattatagt
    85441 aaagccaaat acaaaaggag aaaatgtaca tataccagta atagtaacag aggctggtgt
    85501 acaggatatg gtatataatg attttgaaat tggagaaaat gcagatgttg ttataattgc
    85561 tgggtgtggt atacataact gtggttgtga tgatagtgaa cataatggta tacatagatt
    85621 tttcttacgt aaaggagctc gactaaaata tgtagaaaaa cattatggtg aaggtgatgg
    85681 agaaggaaag agaattttaa atccagttac tattgtcaat atggatgagg attcatattg
    85741 tgaaatggaa acaattcaaa ttaagggtgt agattcaact aaaagagaaa tggatgcaaa
    85801 cctaggtaaa ggagctaaaa tagttgtatt tgagaaatta ttaactcatg gtaatcaagt
    85861 tgcagaatct aatatgaagg ttatcttaga gggtgaaaac tcttctgctc aagtagtttc
    85921 tcgtacagtt gggcaagata attctaagca aaagtttaat ccttgtgtta ttggggattc
    85981 cctttgttct gcacatgttc aatgtgattc aataattatg ggaaattctc aaattagtgc
    86041 tatacctgaa attgctgcaa atcatccaga tgctctttta gtacatgaag cagctattgg
    86101 aaagattgca ggagaccaaa tactaaagat gatgacatta ggtcttactg aagaagaagc
    86161 cgagcaacaa atacttaatt gcttcttaaa gtaaattaaa gattttattt aatttaatat
    86221 aattaatata gtataatata gtgaataagt ctaaaatatt tttattttta ggcttatttt
    86281 ctttatgtaa gaaaagctat tagagaaatt atattgtaat taggatgtgg aataaatgaa
    86341 aaatttactt ataagaaatg ggacaataat atctccaaca gatggtatca aatttgaaaa
    86401 aagagatatc ttggttttac atgggaaaat atatgctatt ggattgaacc ttaaagagaa
    86461 aataagaaaa gaaaaattac ttacaaataa agagttcgag ataataaatg ccgataatat
    86521 gtatatttcc ccaggattta tagatgttca cacccattgt tataagagaa aattacctac
    86581 aggtatggat tctgattcaa ttggaattga aaaaggttct acagttatat ttgatgcagg
    86641 tacagctggt ccctcaaact actatgattt taaaaaaaag tatatggatg agtgtaaaac
    86701 agaagtatat tcttttttaa atgttacaaa tgagggacta aatatattga atgaatcaac
    86761 ttatttagat gttataaatt ttgacaaggt tgagtcaatt gtagaaaaaa atatagaaaa
    86821 gataaagggt ataaaagtaa aagcgagtaa atttcaatct aatgaaagtg gtatagatat
    86881 aattaagaaa tcaaagcaag ttgctaaaaa attaaattta cccttagtgg tatatatagg
    86941 agagtatcca tcatatatag atgaagtaat gaatattttg ggaaaaggag atgtggttac
    87001 accggtatat ggaaatagta caaatggaat ccttaaagaa tctggcacat taagaaaatc
    87061 agtaataaat gcaaagaata gaggagtatt gtttgatgta tgtcatggag tggaccaatt
    87121 tgattttaaa gtttttaaaa aagcaataaa gcaaggttta gagcctgacc taataagtac
    87181 tgatatgcat ataaaaaaca tgaaagacgt aaactattct cttttaaatg ttataaataa
    87241 aattatggaa cttgggatat ccctagaaaa gtgtatagaa aaagtaactg aatacccaac
    87301 aaagattttc gatttacatg gaaataaagg cagaataaag attggtggag aaggtgattt
    87361 tacaatattt acaatggagg agtgtaatga tattataaaa gactacaata ataatgaact
    87421 tgttttaaat aaaaaattaa gattgcaata tactgtaaaa tcatggatga aaagcagtga
    87481 agtttataga catggatacg aaaatactat aataaactaa acaatagtga taaaataata
    87541 aatatatgtt taaattggta tatattggat aaatatctaa ggaaacaaca attaaaaaat
    87601 aataatttta ggggaggtat tttagtatga aagcatttgt tgataaggat gtatgtgtag
    87661 cttgtggagc atgtatagga acatgtccag acgtttttag tatgagcgat gaagggcatt
    87721 cagtagcaat tgaaggagaa ataccagcag atttacaaga tttatgtaaa gaagccgaag
    87781 aaggatgtcc agtttcagct ataacagtta aatagagctg tttaaattta tttttaaaat
    87841 aaatatataa gatttaattg gtacttaagc tatagtatta gaaatttcta ttactatagc
    87901 tttttaaaat agataaactt aatatataag atattacttt ttacaaatat ggaggactga
    87961 aatatgaaaa aaaattatga aatagtatta ttcgatttag atggaacact tacagaccct
    88021 aaagaaggaa taacaaagtc tattcagtat tctttaaata gctttggcat aaaagaagat
    88081 ttggaaaact tagaccaatt tataggacca ccattacatg atactttcaa ggagtattat
    88141 aaatttgaag ataaaaaagc taaagaagct gttgaaaagt atagagaata ttttgctgat
    88201 aaagggatat ttgaaaataa aatttatgag aatatgaaag agatattaga aatgctctat
    88261 aaaaatggta aaatattatt agtagcaact tctaagccaa cagtttttgc agaaactata
    88321 cttagatatt ttgatataga tagatatttt aaatatatag caggtagcaa tcttgatggt
    88381 acaagagtga ataaaaatga agttatacaa tatgtactag acctatgtaa tgtaaaagat
    88441 aaagataaag ttattatggt tggagataga aagtatgaca taattggagc taaaaaaata
    88501 ggtatagatt ctattggagt attgtatggg tatggttctt ttgaagagat tagtgaaagt
    88561 gaacctactt atattgtcga aaatgtagag tctataaaag atattttgtt ataaatatct
    88621 tttatagaca aaaatattac aaaatggtgt cgcatattta aaaatatgat attatagtta
    88681 aggaagtcat ttaaaaaaga ggaggatgca cttaaaatga aatctatttt aattatgggt
    88741 ggaagcgact tcataggttc tgcacttgct aagcgcttga ttaaatgtgg gtatcaaatt
    88801 gatatactta caaatggtaa aaaggaaata gattataatg gttttaaaga acatctaatt
    88861 tgtgatagaa aagttcgaaa agatatggaa aacattatca caggaagaaa atatgattac
    88921 atatatgata tgacagcata tacaaaagaa gatgtaagta atctgattga ttttataagc
    88981 atggataact taaaaaagta tatagtattg tcagcaggag cagtatataa agatagtgga
    89041 agaaatataa aagaagaaaa tgagaaaggt gaaaatgaaa actggggaaa atatgggtta
    89101 aataaaaaag aggctgaaga ttttattata aatagcccta taccatatat aattattaga
    89161 ccaacttaca tatatggtga aaataataat ttatatagag agtattattt ctttgaaaaa
    89221 atagaaaaaa atgaaaagat accagtacca aaaggaaaac aagttagtaa tcaatttata
    89281 tatattgggg atttggtaaa ggtattggaa agcataatga aaaatcctca tgtaagagag
    89341 gcctataatg tgacaaatcc acagttaatt tcttgggatg accttatata tacatgtgga
    89401 gaaattattg gcaaagaacc tataataaaa tatgtagata tggaaaaagt agagtttaga
    89461 gaaagaacgt atttcccatt tagaaatata gactttaatc ttgatataaa taagcttatt
    89521 gaacatgggc tttatatacc aaacgtgtta ctaaaagaag gtcttacagc aacatataaa
    89581 tggttttcag caaataagcc aaaaatgcat gacagaaaaa tgaacaaagt tgagtctgta
    89641 atgcaaatag tttaaaaaaa taaataagta ggtagatatt ttgaactcaa aaattaagta
    89701 ttttttaaaa ttttttatct taatatttat tttgattttt atatactcag ttgcgataga
    89761 gccgagtcta ttaattgtga aaaaatataa tataagtgaa aatggagcat tgataaaaaa
    89821 tgattcaatt gagagtaaat ctgaaagtgt aaaagtagtt caaatttcag atactcaaat
    89881 aggtagtttt tattcaacta agaatctcaa aaaagtagct aataagatta acactttgaa
    89941 tccagatata atagtattta ctggtgattt aattgattac tccaataaaa atccaagtgt
    90001 agatgaaatt acaactattt tatcaagtat gaatgctagg ttgggaaaat tttcagtatt
    90061 tggcaatcat gattatatgt ataaacttcc taggtattat aggcagatta tgaaaaattc
    90121 caacttcaat cttttagtaa atgaaaataa aaaaataaaa ttaaaagatg ataaatatat
    90181 taatatatta ggtgttgatg aaatattaaa tggaaatcct aatataaaat atctggagag
    90241 tcaaatagat aataaaagtt ttaatttatt gttagcacat gaaccagatt tagtagatat
    90301 gcttagtaaa gatacaatga atttagttct atctgggcat agtcatggtg gtcaaataag
    90361 attacctatt aagggagcat tagttactcc tccatatgga aggaaatata ctaaagggtt
    90421 ttatgacata aatggaaatc atttatatgt gagttcgggt cttggaagta caaagttacc
    90481 atttagattt tttaatatac cagagataat agaatttaat attataatct aacataaaat
    90541 atttagaaaa tataattttg ctttttataa tatgtagatg tatatactgt aaaaatggat
    90601 taaaccagta gattgaatga attaatagat ta
//
LOCUS       DAMJWC010000007        85227 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMJWC010000007 DAMJWC010000000
VERSION     DAMJWC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 85227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85227
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.007"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            106..246
                     /locus_tag="PC503_000628"
     CDS             106..246
                     /locus_tag="PC503_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526643.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(421..741)
                     /locus_tag="PC503_000629"
     CDS             complement(421..741)
                     /locus_tag="PC503_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2526644.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(861..1598)
                     /locus_tag="PC503_000630"
     CDS             complement(861..1598)
                     /locus_tag="PC503_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF2526645.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1813..3636
                     /gene="acd"
                     /locus_tag="PC503_000631"
     CDS             1813..3636
                     /gene="acd"
                     /locus_tag="PC503_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF2526646.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISEGNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3851..8149
                     /locus_tag="PC503_000632"
     CDS             3851..8149
                     /locus_tag="PC503_000632"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF2526647.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8353..8814
                     /locus_tag="PC503_000633"
     CDS             8353..8814
                     /locus_tag="PC503_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF2526648.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8844..9998
                     /gene="nusA"
                     /locus_tag="PC503_000634"
     CDS             8844..9998
                     /gene="nusA"
                     /locus_tag="PC503_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF2526649.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10005..10286
                     /locus_tag="PC503_000635"
     CDS             10005..10286
                     /locus_tag="PC503_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF2526650.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10276..10587
                     /locus_tag="PC503_000636"
     CDS             10276..10587
                     /locus_tag="PC503_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF2526651.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10609..12549
                     /gene="infB"
                     /locus_tag="PC503_000637"
     CDS             10609..12549
                     /gene="infB"
                     /locus_tag="PC503_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF2526652.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12592..12972
                     /gene="rbfA"
                     /locus_tag="PC503_000638"
     CDS             12592..12972
                     /gene="rbfA"
                     /locus_tag="PC503_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF2526653.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12953..13936
                     /locus_tag="PC503_000639"
     CDS             12953..13936
                     /locus_tag="PC503_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDF2526654.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEDVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            13949..14854
                     /gene="truB"
                     /locus_tag="PC503_000640"
     CDS             13949..14854
                     /gene="truB"
                     /locus_tag="PC503_000640"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF2526655.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            14985..15914
                     /locus_tag="PC503_000641"
     CDS             14985..15914
                     /locus_tag="PC503_000641"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF2526656.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16018..16275
                     /gene="rpsO"
                     /locus_tag="PC503_000642"
     CDS             16018..16275
                     /gene="rpsO"
                     /locus_tag="PC503_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF2526657.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16515..17360
                     /locus_tag="PC503_000643"
     CDS             16515..17360
                     /locus_tag="PC503_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2526658.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17485..19596
                     /gene="pnp"
                     /locus_tag="PC503_000644"
     CDS             17485..19596
                     /gene="pnp"
                     /locus_tag="PC503_000644"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF2526659.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19862..20605
                     /locus_tag="PC503_000645"
     CDS             19862..20605
                     /locus_tag="PC503_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2526660.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKAGKLSDVFK"
     gene            20763..22010
                     /locus_tag="PC503_000646"
     CDS             20763..22010
                     /locus_tag="PC503_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2526661.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINSVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22045..22290
                     /locus_tag="PC503_000647"
     CDS             22045..22290
                     /locus_tag="PC503_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2526662.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22300..23523
                     /gene="dapG"
                     /locus_tag="PC503_000648"
     CDS             22300..23523
                     /gene="dapG"
                     /locus_tag="PC503_000648"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2526663.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23636..24370
                     /locus_tag="PC503_000649"
     CDS             23636..24370
                     /locus_tag="PC503_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF2526664.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24493..26904
                     /locus_tag="PC503_000650"
     CDS             24493..26904
                     /locus_tag="PC503_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF2526665.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            26907..27965
                     /gene="mnmH"
                     /locus_tag="PC503_000651"
     CDS             26907..27965
                     /gene="mnmH"
                     /locus_tag="PC503_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF2526666.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNDVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            27959..29293
                     /gene="rimO"
                     /locus_tag="PC503_000652"
     CDS             27959..29293
                     /gene="rimO"
                     /locus_tag="PC503_000652"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF2526667.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHKIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29280..29822
                     /gene="pgsA"
                     /locus_tag="PC503_000653"
     CDS             29280..29822
                     /gene="pgsA"
                     /locus_tag="PC503_000653"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF2526668.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30110..31156
                     /gene="recA"
                     /locus_tag="PC503_000654"
     CDS             30110..31156
                     /gene="recA"
                     /locus_tag="PC503_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF2526669.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            31332..32873
                     /gene="rny"
                     /locus_tag="PC503_000655"
     CDS             31332..32873
                     /gene="rny"
                     /locus_tag="PC503_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF2526670.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            33187..35523
                     /locus_tag="PC503_000656"
     CDS             33187..35523
                     /locus_tag="PC503_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2526671.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            35905..37686
                     /locus_tag="PC503_000657"
     CDS             35905..37686
                     /locus_tag="PC503_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2526672.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(37768..38298)
                     /gene="lepB"
                     /locus_tag="PC503_000658"
     CDS             complement(37768..38298)
                     /gene="lepB"
                     /locus_tag="PC503_000658"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2526673.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(38338..39162)
                     /locus_tag="PC503_000659"
     CDS             complement(38338..39162)
                     /locus_tag="PC503_000659"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2526674.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            39419..40327
                     /locus_tag="PC503_000660"
     CDS             39419..40327
                     /locus_tag="PC503_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2526675.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            40471..41916
                     /locus_tag="PC503_000661"
     CDS             40471..41916
                     /locus_tag="PC503_000661"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF2526676.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            42227..42679
                     /locus_tag="PC503_000662"
     CDS             42227..42679
                     /locus_tag="PC503_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2526677.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(43014..44210)
                     /locus_tag="PC503_000663"
     CDS             complement(43014..44210)
                     /locus_tag="PC503_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2526678.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            44595..45545
                     /gene="galT"
                     /locus_tag="PC503_000664"
     CDS             44595..45545
                     /gene="galT"
                     /locus_tag="PC503_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF2526679.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            45706..46458
                     /gene="xth"
                     /locus_tag="PC503_000665"
     CDS             45706..46458
                     /gene="xth"
                     /locus_tag="PC503_000665"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF2526680.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(46550..47326)
                     /locus_tag="PC503_000666"
     CDS             complement(46550..47326)
                     /locus_tag="PC503_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2526681.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKSSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMWKTNQFTLENVKQRKNK"
     gene            47641..49539
                     /locus_tag="PC503_000667"
     CDS             47641..49539
                     /locus_tag="PC503_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF2526682.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            complement(49667..50788)
                     /locus_tag="PC503_000668"
     CDS             complement(49667..50788)
                     /locus_tag="PC503_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF2526683.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            50987..51319
                     /locus_tag="PC503_000669"
     CDS             50987..51319
                     /locus_tag="PC503_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2526684.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            51306..52364
                     /locus_tag="PC503_000670"
     CDS             51306..52364
                     /locus_tag="PC503_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF2526685.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINENSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            52357..53427
                     /locus_tag="PC503_000671"
     CDS             52357..53427
                     /locus_tag="PC503_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2526686.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            53529..54065
                     /locus_tag="PC503_000672"
     CDS             53529..54065
                     /locus_tag="PC503_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2526687.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            54181..54888
                     /locus_tag="PC503_000673"
     CDS             54181..54888
                     /locus_tag="PC503_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2526688.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            54890..55606
                     /locus_tag="PC503_000674"
     CDS             54890..55606
                     /locus_tag="PC503_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2526689.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIASILIILLFMWQIPLCMFLASKFGMFVTVLTNMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            55608..56366
                     /locus_tag="PC503_000675"
     CDS             55608..56366
                     /locus_tag="PC503_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2526690.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            56501..57889
                     /locus_tag="PC503_000676"
     CDS             56501..57889
                     /locus_tag="PC503_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF2526691.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(57965..58786)
                     /locus_tag="PC503_000677"
     CDS             complement(57965..58786)
                     /locus_tag="PC503_000677"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF2526692.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYNRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            59022..60191
                     /locus_tag="PC503_000678"
     CDS             59022..60191
                     /locus_tag="PC503_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2526693.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            60374..60574
                     /locus_tag="PC503_000679"
     CDS             60374..60574
                     /locus_tag="PC503_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2526694.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            60995..61423
                     /locus_tag="PC503_000680"
     CDS             60995..61423
                     /locus_tag="PC503_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2526695.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(61566..62321)
                     /locus_tag="PC503_000681"
     CDS             complement(61566..62321)
                     /locus_tag="PC503_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2526696.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(63022..63528)
                     /locus_tag="PC503_000682"
     CDS             complement(63022..63528)
                     /locus_tag="PC503_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526697.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            complement(63610..63930)
                     /locus_tag="PC503_000683"
     CDS             complement(63610..63930)
                     /locus_tag="PC503_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2526698.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            64099..64296
                     /locus_tag="PC503_000684"
     CDS             64099..64296
                     /locus_tag="PC503_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526699.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            64401..64841
                     /locus_tag="PC503_000685"
     CDS             64401..64841
                     /locus_tag="PC503_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526700.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            65090..65533
                     /locus_tag="PC503_000686"
     CDS             65090..65533
                     /locus_tag="PC503_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526701.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            65538..66602
                     /locus_tag="PC503_000687"
     CDS             65538..66602
                     /locus_tag="PC503_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2526702.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            66616..67044
                     /locus_tag="PC503_000688"
     CDS             66616..67044
                     /locus_tag="PC503_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2526703.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYIGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            67170..67616
                     /locus_tag="PC503_000689"
     CDS             67170..67616
                     /locus_tag="PC503_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2526704.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            67643..67810
                     /locus_tag="PC503_000690"
     CDS             67643..67810
                     /locus_tag="PC503_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526705.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            67810..70263
                     /locus_tag="PC503_000691"
     CDS             67810..70263
                     /locus_tag="PC503_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526706.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MILAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     VWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            70263..70685
                     /locus_tag="PC503_000692"
     CDS             70263..70685
                     /locus_tag="PC503_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526707.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            70967..72496
                     /locus_tag="PC503_000693"
     CDS             70967..72496
                     /locus_tag="PC503_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2526708.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLNVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            72512..72838
                     /locus_tag="PC503_000694"
     CDS             72512..72838
                     /locus_tag="PC503_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2526709.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            72838..73266
                     /locus_tag="PC503_000695"
     CDS             72838..73266
                     /locus_tag="PC503_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2526710.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            73259..74311
                     /locus_tag="PC503_000696"
     CDS             73259..74311
                     /locus_tag="PC503_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2526711.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            74308..75006
                     /locus_tag="PC503_000697"
     CDS             74308..75006
                     /locus_tag="PC503_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2526712.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            75007..75990
                     /locus_tag="PC503_000698"
     CDS             75007..75990
                     /locus_tag="PC503_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2526713.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKVD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            76007..81328
                     /locus_tag="PC503_000699"
     CDS             76007..81328
                     /locus_tag="PC503_000699"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526714.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFIKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDIFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHVFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYICNDVSIIVKNDNTCYVCGFVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAESNEPQA"
     gene            81345..81698
                     /locus_tag="PC503_000700"
     CDS             81345..81698
                     /locus_tag="PC503_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526715.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            81961..82221
                     /locus_tag="PC503_000701"
     CDS             81961..82221
                     /locus_tag="PC503_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526716.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(82442..82897)
                     /locus_tag="PC503_000702"
     CDS             complement(82442..82897)
                     /locus_tag="PC503_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526717.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(83125..83544)
                     /locus_tag="PC503_000703"
     CDS             complement(83125..83544)
                     /locus_tag="PC503_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526718.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            83843..84052
                     /locus_tag="PC503_000704"
     CDS             83843..84052
                     /locus_tag="PC503_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526719.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            84084..84293
                     /locus_tag="PC503_000705"
     CDS             84084..84293
                     /locus_tag="PC503_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526720.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(84510..84908)
                     /locus_tag="PC503_000706"
     CDS             complement(84510..84908)
                     /locus_tag="PC503_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2526721.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
BASE COUNT        34100 a         9272 c        14833 g        27022 t
ORIGIN      
        1 aataaaaaaa tttttattta ttagagtttt tggaaataat aataacagat attataatta
       61 attaacagtt tttgtaagta tttgacaata gagagggtgt aacaaatggg aataatagag
      121 tcagcatcaa aattggctga gatggttcat ttattggctg ttgaaaaggg gataactgat
      181 atagaagcat gggatgaagc tgtgaaagaa tacagcaaaa tttatgaaga aagaagaaat
      241 gaatagaatg ataaaaaatg aaaacttgat gataaaaaat aactttattt aaagaaattc
      301 aatttttata gaagtattaa aaataatata aataaaaaga tggtatttca aatgtaagta
      361 aaaaatcatt ttgggatacc atccttatta tttattttaa taatatataa gtaataaatc
      421 ttacttatcc atatttttta tgtaacctct tttttctaac ttttttatat gctccttacg
      481 tatttcatca agattaatac catattgttc ttctagctta aacatcatag taacacatgt
      541 ctgagctaca tccattagtt ccttagcagt tttctttata atatcaactt catctaaatc
      601 attattttct ccacttagat ttctgaattt acctatacat tcagctaatt caccttgttc
      661 ttcacccatt ttgataaatg tagattctag tgttgggtct aaattattaa gctctggtaa
      721 agatatagtt tttagtttca taaaagctcc tttcaagtta ttcgtattta tactaaaaca
      781 tcataacaaa aataatacta aaaaaaaact ttaaattcaa cataaaaact tacatatata
      841 ataaaaatcg tgaaataaat ctatatttgt cttaatacag cctcatataa aacttctcca
      901 ataggtttat ttattacaag agaagctgac ttatcataga ctgtatttgc tttattaata
      961 agagcaatat aatcaccttt gtaataatct ataaaacttg ctgctgggta cacagctaat
     1021 gatgtacctc ctataatcaa taaatcagca ttacttatag cagaaattgt tttagtaatg
     1081 acatcactgt caagagcttc ctcataaagt actacatctg gttttactat agaaccacag
     1141 ttgtcacagt aaggaatatt acctcccaga tttaacatag attctaagtc aaaaaactta
     1201 ccacatttag tacaataatt tctatgtaca gaaccatgaa gttctagcac atttttactt
     1261 ccagccattt gatgaagtcc atcaatattt tgagttatga cagctttaag cttacccatt
     1321 tcttcgagtt ttgctaaagc tatatgagca ttattgggtt ttgcattagg atatattaat
     1381 ttatccttat aaaattcaaa aaattcttct ggatatctaa caaaaaaagt atgtgaaact
     1441 aattgttcag cagtaaattg tttattgagt ttttggctaa ataatccagt agaacttcta
     1501 aagtctggaa tattagattc agttgaaaca cctgctccac caaaaaatac aatattattg
     1561 tgattagcta ttaagtcttt taagctattt gcatccatag ttacacctcc aaattattat
     1621 atataaattg tactacatat taggtcgttt atgttttatt aatttaaata aatatatagt
     1681 ttaataagtt aaataaaggg aatataaata aaatgtatac agagtataaa tagacaatat
     1741 ttactaaaat aacaagttgt cgtataatta tattaaaatt gttttagtgt ataagaaggg
     1801 cgggggaagt acgtgaagaa aaaagcagct ttagcaacat tggctatgtt acccttaggt
     1861 gtggtaaatg cacatgctga tggagatata ggtatagtga ctataaatta tttaaatgta
     1921 agaaatgaac caactgccga aagtagcata gcctttgttg ctaaaaaaga tgataaagtt
     1981 ttgattaaag actcttctaa tggatggtat aaaataaaag ctgaatctgg acaagaaggt
     2041 tgggcttcat caaaatatat agcaaaatca aatagtgact ctttaagaac gtctacaaat
     2101 aaagaaaaac aagttatttc aaatagttta aatatgagaa atggagcagg tacaagttac
     2161 agagtaataa ctgtactaaa aaaaggtcaa aaagtagaag taatatcaga gagtaatgga
     2221 tggtctaaaa tcaaatatga tggaagacta ggatatgtat ctagctctta tttaggagac
     2281 gtttcaaact caactaataa atcaaaaact aaacaagtga atacaacttc actaaatgta
     2341 aggagtggac caaatacaag ttatggtttg ttaggcaagt tgccaaaagg aagtaaagta
     2401 gaagtaatat cagaaggtaa tggatggtcc aaaataaagt ataatggaaa agatgcctat
     2461 gtatctagta tgtacttatc ggatgtaagt caaagtaatt cagacaattc tagtcaaagc
     2521 aatgataaaa agaatactga taaggtcgta aatacagctt ctttaaatgt aagaagtgga
     2581 ccaggttcta catatagtaa gttgggaaaa gtttataaag gaagtaaagt aactgtacta
     2641 tcagaaagta gtggatgggc taagattaat tttaacaata aagaagcatt tgtagtaggc
     2701 aattatttat ctacttcagc agatacttca aataataact caaatagtaa ctctgataac
     2761 agttctaata gtaatggcaa taattcttca tcatcaggtc aagtaaatgg tatgtcaggt
     2821 ataagtgggg ctaaaattga ttataaatct ttgagttata ctttagaatc tcatataagt
     2881 aaacaagttg agaaagcagc atcaggagga aatgtgatag ctccaagtaa taggaaaagc
     2941 actccaagtc ctgaatttag tactttttca gctcaaagaa caagctcatt tgtaaatgca
     3001 agttcaagtg atatagaata ttatttaaat cctaaaaatt ttacaaatac tactaaaggt
     3061 atgatgcagt ttttaaagat taacagttat agagatggta tttcagaatc aagtcttaac
     3121 tcgtatctta atggtttatc ttctagtgta tttaaaaacc agggagcagc ctttataaat
     3181 gctgccaaga agtataatat agatgttgta tatctagtat ctcatgctat gtgggaaact
     3241 gcttatggta agtctacact tgcccaaggt caaacattaa catcttataa gggacaacct
     3301 cttagtaagc cagttaaagt atacaatttt tttggtatag gagcaataga taaaagtgct
     3361 aatgtttcag gtgcagaagc agcgtattcc aatggctgga ctagtgtaga agctacaata
     3421 gatggctctg caaagtggat atcacaaaat tacgtaaata gttctaagta caatcagaat
     3481 actatctaca agatgaagtg gaattatgat tatacatggc atcagtatgc aactgatgtg
     3541 aactgggcta atggaatttc tggaattatg gaaaatttaa ttggtcttta tggaggagga
     3601 agtagtttgg tttttgaagt tcctcaatac aagtaataca taaataaaaa atatagacta
     3661 tgggtagttt tcattttatt taaattatct atagtctttt tgtatataat ttataatctg
     3721 taaatttaat gctaacaaaa cttttatgtt ataatattaa ttctaagtaa atataagtga
     3781 gtaataggta gaaatagata aaaagtggta ataatatata taaagataat tttgagaaag
     3841 gaggatatat atggaaagta ttaaggaata tttggataag ttagaaatta ataatagtgg
     3901 tcttggaaag caacttaaag aagtttatat aaatagagta gtttatttta aggaagataa
     3961 gatagtttat ttttatctaa cttctaaaga tattgtttct catgaacttt tagataaatt
     4021 taaagaagaa ttgatgtata aactcgatta ttttaaagat atgaggatga agataagatt
     4081 tactggtctt gaaagaaaat ccaataaaga tgttataaaa aaatattgga ataatatatt
     4141 gtatatatta aagtatcttt gtccatctat tgcagggtgg tataaacaag tagaatttct
     4201 ttgtttagaa gaagaattaa aaataaaact tccaaaaggt atattttatg agcgattaat
     4261 gaaaaaaaat gtaacttatg tacttaaaac cgtgcttagc gaagagttgg gattagattt
     4321 aaatataaca atagaaaaag ctgttgatga aaaggtaaat aaagaaagac tcataagaat
     4381 caatgataga gaaatggaag aaaaaattag ggctttagaa attggaaaag ttaataactg
     4441 tgaagaaaat gaagaggaaa gttatgtcat taagtctgat gtagatgaaa atttaatcta
     4501 tggagataat gcaaatgcta tgattgaaaa tatagttgaa ttaaatgcat cttctggaac
     4561 agttgcagtt gttggagata tatttgatgt tgacactaaa gaacttaaaa acggaaaaat
     4621 acttatgata gcttcaatta cagattatac tagctcaata agctgtaaac tttttttaac
     4681 agatacaaat aaggatggag tacttgaaaa tgttaaaaaa ggagcatact taaaaatcaa
     4741 gggtgacata gtttatgata catatcaaag agaaattagt atgatgatta gtgggataag
     4801 aaaagaaact agaatagaga gagaagataa atcagaggaa aaaagagtag aactccatgc
     4861 acatacacaa atgtcttcta tggatgctat ttgttctgtt aaaaagcttg tagagcgtgc
     4921 agccaaatgg ggtcattctg ctattgctat aacagaccat ggtgttgtac aaggatttcc
     4981 agatgctatg aatgcaggta agtcaaataa tataaaaata ctttatggag tagaagggta
     5041 cttggttgaa gatgattctc tcattataga ggatgcaaat gataaagaac tttcgcagac
     5101 atttgttgta tttgacatag agacaactgg tttttctaat acaaatgata aaataactga
     5161 gattggtgct gtaaaaatag aaaactttaa gattgtagat agatttagtg agttaataaa
     5221 tcctgaaaaa gatatttctt ataagataca ggaattgaca ggaataacta atgaattaat
     5281 taaagacaag ccaaccattg aagaagttct tcctaagttt atggaatttg ttggagatag
     5341 tgtattagta gcacataatg cagagtttga tactggattt atatcgcaaa aatgtaggga
     5401 acaaggcttg ttatataata acaaaaaagt agatacactt atgttagcaa gagtaatgtt
     5461 gccaaactta aaaagacata gattaaatgt cgttgcaaaa gaacttggta ttcctctttt
     5521 aaatcaccat agagcagtgg atgatgctga agctacagca cttatattta ataagttttt
     5581 gcagatgctt acagaaaaag gtgcaaaaac tctaagtgat gtaaacaata tacttggaaa
     5641 gattgattac acaaagctta gcacaaatca tataaccttg atagcaaaaa attctatagg
     5701 tataaaaaat ttatataaaa taatttcaga tgcacatgta aatcattttt ttagagcacc
     5761 aagaatcctt agaagtgtat taaatgaata taaagaagga ttaataattg gttcggcttg
     5821 tgaagctggg gtggtttttc aagctgtaaa gaaaaacgtg tctgatgagg aaatgaaaaa
     5881 aataatagat ttatacgatt atattgaagt aatgcctata gataataata gatttatgat
     5941 tgataaagga gaagtaaagg acgaagaaga gttaagggag ttgaatagga aattaattga
     6001 tacagccaaa aaatttgaca aaattccagt agctactggg gatgttcatt ttttagacaa
     6061 acatgaagct gtcttaagaa aagttcttaa atattctcaa ggttttaaag tagatgaaga
     6121 agaaacttat ttacatttta gaacaacaga tgaaatgttg gaagagttta gttatcttgg
     6181 agaagaattg gcatatgaag ttgtagttga aaatagtaat ctgattgccg atatggttga
     6241 agatataaaa cctataccag atgatactta tcctccaatt atagagggct cagatgtgga
     6301 gttaagagaa atgtgttaca aaaaagccaa acgaatctat ggagacccaa taccagaaat
     6361 agttcaaaaa agactggata gagaattaaa ttcaataata agcaatgggt atgcagttat
     6421 gtatattata gctcaaaaac tggttgcaaa atctctttca gatggatatt tagttggttc
     6481 aagaggctca gttggctcat cttttgcagc tactatgagt gatataacag aagttaatcc
     6541 tcttccagca cattatattt gtgaaaacga agactgtaaa tattcattct tttatgaaat
     6601 aggtgaatgg ggctcaggtg ttgatttacc agacaaggat tgtccaaagt gtggaagaaa
     6661 acttgctaaa aacggtcatg atattccatt tgaggttttc ttaggttttg aaggtgataa
     6721 agaaccagat atagacttaa atttctcagg aaattatcag ccaacaattc ataaatacac
     6781 agaagaacta tttggagagg ggtatgtata tagggctggg actataggta ctgtagcaga
     6841 aaaaacagct tttggatacg caagaaaata tgtggaagaa aataatataa gtgtaccaaa
     6901 tgcagaagta cttaggcttt caaatggatg tactggagta aaaagaacct caggacaaca
     6961 tcctggtgga gttatggtta taccagacta taaagatgta tacgatttta cacctataca
     7021 gtatccagca aatgatactt cttgtggtgt tataactact cactttgatt atcattcaat
     7081 aagtggtaga atacttaaac ttgatatact tggacacgac ggtcctacca ttataaggat
     7141 gcttgaagat atgactggaa taaatataac agaaattcct ttagatgata aagagactat
     7201 gtctctattt acatctacag aagcattagg tgttacacca gaagaaataa actgtcctat
     7261 aggttgcctt gctgtaccag agtttggaac taagtttgta cgacaaatgt tacttgacac
     7321 aaaacctact acatttgcag aacttgtacg tatatctggt ctctctcatg ggacagatgt
     7381 ttgggtaaat aatgcacaag acttagttag agaagatata gttggattaa aagatgttat
     7441 atctacacga gatgacataa tgaactattt aatatttaaa ggattacctc ccaaaatgag
     7501 ctttacaata atggagagtg taagaaaagg taaaggttta aaaccagaac acattgaaga
     7561 aatgaaaaaa aataatgttc cagaatggta tataggctca tgtaaaaaga ttaagtacat
     7621 gttcccaaaa gcacatgctg ttgcttatgt aatgacatca tttagaattg catattgtaa
     7681 agttcactat ccagaagcat tttatgcgac ttattttacg acaaaagttg aggattttga
     7741 tgcagattta attgttaaag gattagatgc tataaaatca aaaataaatg aaattgagtc
     7801 actgggaaat gatgcaacca caaaagaaaa aggtatgttg accgttttag aagttgctct
     7861 tgaaatgtat gctagaggaa taaaattatt accagttgat atatataaat cagatgcaac
     7921 tgagtttata gttgtaggag aaaaaacatt acttccacca atggcagcaa tacaaggtct
     7981 tggaggaaat gcggctataa acatccaaaa tgaaagaaaa aatggtgaat ttatatcaaa
     8041 agaagatttg agaaagagaa caaaaatatc aaaaacggta atagaaactc ttactaatca
     8101 tggttcactt gagaatatga gtgagagaaa tcaattgtca ttgttttaag ttagcccaaa
     8161 aagttgcaaa taaaagaatt ttatgatatc atagtataga aaatagtata ctttgcagaa
     8221 actaagagtg agacagctgt tctcactctt ttattttaaa tatattatta aaaagctggt
     8281 ttatttttat taaatatatt ttatttaaga ttatataaac tggtcattta caattgaata
     8341 ggaggaactt taatgaaaaa aaatttagaa gctacaattg aggagattgt aactaaaata
     8401 acggatgaac atggatttga aatggttgat gttgaatatg taaaagaagc aggagaatac
     8461 tacttaagag tatacataga taaagaagaa ggaatatctt taaatgaatg tgaattagtt
     8521 agtagagaat taagtccaat actagatgaa aaagacccta taaaagaaaa ttacttttta
     8581 gaggtatctt ctccagggct tgatagagca ttaaaaaaag acagagattt tgttagatat
     8641 caaggtagag atgtagattt aaaattatat aaaccattaa atggatgtaa gcaatttgaa
     8701 ggtgaacttg taggattaac agaagataat aatataaaaa tcattgcaaa tggtaaggaa
     8761 atggaattta atagaaaaga tgttgctatt gtcagattag caataaagtt ttagtggtat
     8821 attaaatagg gaggatataa aaaatgaatc atgaatttat ggaagcatta gatgaattag
     8881 tagttgacag aggtatagat aaagaaatac ttatagatac tatagaacaa gctcttttaa
     8941 ctgcatacaa gaaaaacttt ggttcagcac aaaatgttag agttgaattt gatagagaca
     9001 agggagatat aaaagtattt tctcaaagag ttgttgttga tgaatcagat ttatatgata
     9061 ctttcttaga aatagagtta gcagatgcta gagagataaa ccctaattat gaattaggtg
     9121 atattataga acatgaagtt acacctaaaa actttggaag aattgcagct caaacagcaa
     9181 agcaagtagt tgttcaaaga ataagggaag ctgagagaga aatagtgtat aatgaattta
     9241 tagaaaaaga aaatgaaata gttacaggag aggttgctag agcaaataaa aatgttgttt
     9301 atgtaaatct tggaagaata gaaggtataa tgactcaaag tgaacaaata ccatttgaga
     9361 attataaagc aggtcaaaaa ataaaattct atatacttga agttaaaaag actaacaaag
     9421 gacctcaaat agttgtatca agaagtcatc cgggtctagt aaagagattg tttgaagaag
     9481 aagttcctga aatatatgaa ggaatagttc aaataaaatc tgtagcaaga gaagcagggt
     9541 caagaactaa aatggcagta agatctatag atgaaaaaat agacccaatt ggagcttgtg
     9601 ttggaccaaa aggacttaga gtaaaaaata tagtggatga acttggcgat gagaaaatag
     9661 atataataaa atatagtgaa gacccagcag agtttatatc agcagcactt agcccatcaa
     9721 aggttgttag agtagatata gatgaagatg aaaagtctgc cttagtaatc gttccagatt
     9781 atcagttatc gcttgctata ggtaaagaag gtcaaaatgc aagactagca gcaaaattga
     9841 ctaactggaa aatagatatt aagagcgaat ctcaagcaga acaagaaatg ttaaatcttg
     9901 aaaattccaa agaaatagaa gctgaggatg ttgaagctga atttatcgac caagaagagt
     9961 tagatacttc agaggataat tttagtgaag aagagtaagg agggatgatt ttgaaaaaag
    10021 taaaaaaagt gcctcaaaga aaatgcatag catgtcaaga tagagactct aaaaaagagc
    10081 ttataagaat agttaaaaat aaagaaggaa aaatattttt agacccaaca ggaagagcca
    10141 atggaagagg agcatatgta tgtaaaagct ctgaatgtct aaaaaaagct ataaagagta
    10201 aagcattaaa taaagctttt aaaatagatg ttcctgatga agtctatgat aatctactta
    10261 tggagttaga agaatatgaa aaataataaa gaaaaagtac tttcgttctt agggctcgca
    10321 actcgtgcag ggaaaatagt gtctggtgat gattcaactt tgcttgacct taaaaaagga
    10381 aaagtaaatt tgattttaat cgcagaagat gcatcaaata atactaaaaa actttttaaa
    10441 gataaatcaa cttttagaaa tattccatat ctattttttt caacaaaaga ggaaatagga
    10501 tttgcaatag gaaaatctcc aagagcagtt gtaggaataa aagatgaaaa tttttctaaa
    10561 aagataattg aactaataga aatttaaaat aaaatagggg gtgatcttgt gtcaaaaaca
    10621 agagtatacc aaatagcaga agaattaaat atatcaaatg aagagcttat aaataagtta
    10681 gctgaattag atataaatgt aactgacaaa gattcagtat tagaaggtga agagttagaa
    10741 ttagcacttg aaatgttagg tgaagattta tctcaagaaa atggaaatgt tatagaaata
    10801 gatggaaagt tgacagtaca agtattagca acgaaattag ataaatctcc atcagaaata
    10861 attatgaagc ttatgaaaat gggaactatg gcaacaataa atcaagagat aagttttgag
    10921 attgctgctt tggctgccaa agactatgga tttgaattaa cagtagctga aagtgatgat
    10981 acagaagctt tagaaataga agctttaatg gaaattgaag aagataaaga agaggattta
    11041 aaacctagac caccagttgt tacagttatg ggacatgttg accatggtaa gacatcttta
    11101 ctagatgcaa taagaaaaac tgatgtgatt tcaggtgaag ctggaggaat aactcagcat
    11161 ataggtgctt cagaagttaa aatcaatgga cacaaaatag tatttttaga tactccagga
    11221 catgaggctt tcacatcaat gagagcaaga ggagcacaag ttacagatat agcaatatta
    11281 gtagttgcag cagatgatgg tataatgcct caaacagttg aagctataaa ccatgctaaa
    11341 gcagcaggtg tacctttaat agttgctatt aataaaatag ataaaccagg tgcaaaccca
    11401 gataaggtta aacaggaatt agcagaccaa ggattattag ttgaagactg gggtggagaa
    11461 gtaatagcag ttccagtatc agctaagaaa aaagaaggaa tagatacact tttagaaatg
    11521 gtattattgg ttgctgaaat ggaagagtta agagctaatc caaataaaag agcagtagga
    11581 actgttatag aagctgagct tgataaagga agagggccag ttgcaacagt acttgttcaa
    11641 ggtggtactt taacagtagg tgacccaatc gttgcaggtg ttgcatgtgg taaagttaga
    11701 gcaatgataa atgcaaaagg taagagagta aaaacagcag gaccatctac agcagtcgag
    11761 atattaggtc tatcagaagt tccacaagga ggagaccaat ttgtcgaagt tccaactgat
    11821 aagattgcta gaagtgtagc agcaagaaga caacaaatag ttagagatga aatgttaaaa
    11881 tcaactcaaa gattatcact agatgctcta tttagtcaaa tgagtgaagg ttctataaaa
    11941 gaccttaata tagttataaa agcagatgta caaggttcag tacaggcagt taaacaatct
    12001 ttagaaaaat tatcaaatga agaagttcaa gttaaagtaa tacatggtgg tgttggagct
    12061 gtaacagaat cagacatatt acttgcagca gcttctaacg caataataat aggattcaat
    12121 gtaagaccag ttccaggtgc agaatctcta ggagaaaaag aaaatgttga tataagaaca
    12181 tatactataa tatacaaggc aatagaagat atacaagcgg ctatgactgg tatgttagac
    12241 cctgaatatg ttgatgaaga aacaggaaaa gctgaaataa gagaaatata taaaatatct
    12301 ggtgttggaa cagtagctgg atgttatgtg actaatggta agatatttag aaattgtaaa
    12361 gtaagattag ttagagatag cataataata catgaaggtg agcttgcagc acttaagaga
    12421 tttaaagatg atgtaaaaga agttaattct ggatacgaat gtggtatgag ttttgtaaat
    12481 tataacgaca taaaagaagg cgatatagta gaagcttata taactaaaga agtagaaaga
    12541 aaattataaa ttcgtatcaa agaaaatcag ttagtaaaga aggtcgatgg tatggcatca
    12601 tataatagaa caagaaggat agcagaagaa ataagaaaag tcgtaagcac tatgcttata
    12661 aatggagtaa aagaccctag aataacatct atggtgagtg taactgatgt agaagttaca
    12721 aatgacctaa gatatgctta tgtatatgta agcattctag gtggagatga agaatccaca
    12781 ctaacaggtc ttaaaagtgc tggaggatat ataagaagag aagtaggaaa aaatataaaa
    12841 cttagatata ttcctgaaat agtatttaaa cttgatgatt caatagaaaa aggaatgtat
    12901 atggatagcc ttataaaaag agttaatgaa aaaaatgctc aacaaaatga ggatgaaaat
    12961 tatgatgaat aatatggata gtattataaa ctatatttat gagggtgact attttatagt
    13021 tacctctcat atcagtccag atggagacaa tattggttct acactttcaa tgtattatac
    13081 attgaagaat ttaggaaaaa atgtatatta tgtacttgat gatgaagctc cattaaattt
    13141 aaggtttttg gttgaagatg taaaaatcta taagtctaat gaatttaata tgaagaacta
    13201 ttctctaatt gcacttgatt gtggggataa gatgagaata tgtgtgagtg atgaaatcaa
    13261 aaataatgca tcaaaattaa tctgtattga ccatcatgct agtaatgatt catatggaga
    13321 tttaaattat gtagatattg atgcatcttc tacatgtgaa ttagtttata atttattagt
    13381 tagatttcag caaataaaag atattaatat tataaatgaa gatatagcaa catgtttata
    13441 tacaggtctt gtaactgata ctggaaactt ttcgtattca aatgtacatg caagtagctt
    13501 tgaaatggca aaaaatttac ttgttttagg tgcacaaaaa aatactataa tacaaaatat
    13561 atatcaaagc aattcttctg gttattacaa attattagga gaagctctaa agggtttgga
    13621 gatatttgat tcaaaggtat ctagtatagt tttaactcaa gacatgatga atagaaataa
    13681 tattagcttt aatgatgttg atggaataac aacatataca agagacataa aaggtataga
    13741 agttggaatt ttatttaaag agaaaaaaca aaatgaaatt aaagtgagtt ttaggtcaaa
    13801 aaattatgtt gatgtaagtg aaatagccaa gttatttggt ggtggtggtc atgtaagggc
    13861 tgctggatgt actattagag atagtattga taatgcaaag aaaatggtac tagaggcagt
    13921 gttaaaatca atttaaggtg acagtaaaat gaataagatt ataagtatat tgaaacccac
    13981 aggtatgaca tctcatgatg ttgtaagtag agtgagaaag attttaaata taaaaaaagt
    14041 tggtcataca ggtactcttg acccagatgc ttcaggtgtt ttaccaatct gtatagggaa
    14101 agctacaaaa gtatgtgaag ttattttaaa caaagataaa tcgtatatat gtgagcttac
    14161 tttaggtata agtacagata cttatgatgc ttcaggtgaa attttaaaaa aagttgatga
    14221 ttttaaattt agtaatgaag acatagaaag agcttttgac acacaaagag gagagataaa
    14281 tcaacttcct ccaatttatt cagctttaaa ggtaaatgga aagagaatgt gtgatttagt
    14341 aagaagtggt agacaatctg aaattacttt aaaaacaaga agagtaaata taaaagacat
    14401 aaaaatacta agtataaaag gtaataaagt aatgttttat gttgagtgtt ctaaagggac
    14461 ttatgtgaga agtatttgcc atgatatagg agaatatcta ggttgtggag ctcatatgtc
    14521 gtttttgaat agaacatctt ctggtaaatt tgacttagat aattcaataa cattagaaga
    14581 attagaatta ttttatgaaa ataaaacttt agacaaatac ttatatgata tagattatgt
    14641 ccttgattcg tttaattatg ttgtattaaa ccctaatgct ataaaatatt atagtaatgg
    14701 tggctcaata gatgataaaa ggtttttaaa gaataatttc gataaagatg atgaatttgt
    14761 aagagtatac agtacagata atttcttagg attaggaaag ttatcaaaac acaataatac
    14821 aataagtgtt aaaagtgata agatgttcat ataaccaatg tatttaaaaa aacaacaaaa
    14881 gagatagtac tataataact tctatagtct atctctttta cttatgctat aatagtttgt
    14941 gaataagtta agagtaaatt atattttagc ggggaacatt tattatggtg attataaaat
    15001 ctataaaaga aatagcaaac ataaaagaaa gtgtcattac cataggaaat tttgatggtg
    15061 tacacaaagg acatcaagtt cttataggaa aaacagttga acatgcaaaa aaagaaaata
    15121 tacagagtat tgtatttaca tttgcaaatc atcctgtaaa ttactttaga ccaaactcaa
    15181 caaaaaatat tataagcaat gatgataaaa taaaattatt agaagatttg ggaatagata
    15241 tagttgtaat cataccattt gatgagtata tgactaaaat acctgcaaag gatttcgtag
    15301 atgagatact agtaaaaaaa ttaaaagcta aaaagatagt aattggacat gactttacat
    15361 ttgcaagggc aaaagaaggc aatgttaatc tattaaaaag cttagaacat gaatttggtt
    15421 ttgaggtaga agtaataaaa cccatcaaaa tcaatgatgt aagagtgagt agtacttata
    15481 ttagaagttt agtatcccag ggtgatatgg ctaatgtcaa ggaatatttg ggtagaaatt
    15541 acaagttaga aggttgtgtt atacattcta aacaccttgg aagaactata ggattcccaa
    15601 cggcaaatat tgaccttaag aataatatgc tcgttccaaa gagaggtatt tatgcttcta
    15661 ttgtacatat tggagatgag acttattttg gtgctacaaa tgtaggctat aacccaacag
    15721 ttaatggaaa aactttgtct attgaaacaa atattttaga gtttgataga gatatttatg
    15781 gggaaaatat aattgttgaa tttttggaaa gaataagaga tgaaagaaag tttaattcaa
    15841 tagatgactt aaaaaatcaa ttgtataatg atacaaatta tgtgtatgaa aactatgttt
    15901 gcaaaaacaa gtaatgtatg ataaaatgat taaggaaaat aaccattact cggcatttga
    15961 atactccaat caatgcttag taataggcgt ttctaaaaaa atacggaggt aatctaaatg
    16021 ataaacaaat cagaaataat aaaagaatat ggaagagctg aaggggatac tggttctcca
    16081 gaagtacaaa tagctttatt aacagctaga ataaacgagt taaatggaca tttaaaaact
    16141 cataagaaag accaccattc aagaagagga ctattaaaaa tggttggtag aagaagaaac
    16201 ttattagctt acttaaagga aaaagatctt gaaggatata gagcattaat agctaaatta
    16261 ggattaagaa agtaatttca ttctttataa aaaagcaggt atagtgtata cctgcttttt
    16321 tatagttaat tcattataaa gtaaaatagt taataataaa agtagtttat atgttataaa
    16381 aaattataaa atgaataata ttgggtaaga atattaaaat agtatacaaa tacataatca
    16441 atttaaaagg aaagacagga taaatataga aattttataa caggataatt agttggaata
    16501 aggaggatat tattttgaaa ataaagttag tatgcgatag tttgtgcgat attccagatg
    16561 aaatatcgga aaaagattat atagagatag ttccacttac agttattttt aatgataggg
    16621 aatatataga aggagtagat ataaagaaag aagagtttta taaaaaagta aaagaaatca
    16681 agcaaatacc taaaacttca caagctacat atatggagtt taaagaagtg tttgataagt
    16741 tcataacaga aggttatcat ataatctgta tgacaggggc tgcaaacgca tcaggaactt
    16801 ttcaaagtgc tatgatagct aaaaatgatg taaatgaaaa tgaaaaaata catatatttg
    16861 atactagaaa tttatctcta ggtagtggac aatatgttat aaaggcatgt gaacttcttg
    16921 aagaaggact gggatttgaa gaaattatag atgaattaga aaatactcgc agtagtgtaa
    16981 gattgctttt tgcaccatat acacttgatt ttttaaagca gagtggaaga gttccagttg
    17041 caactgcttt gataggaaat atgttaaata taaagcctat atttttcttt gataatgggg
    17101 aagctaagtt ggtaaataag gttagaggaa taaagaatat agcaagtaaa ttggtcgata
    17161 taattttaga aatgaatgaa gggtctttag aaggaaaaat cgtcacaata ggttgtggag
    17221 ataatttaca cgattgtgaa atattaaaag atgaagtaaa taaaagaata aaagcaagaa
    17281 gagtattatt tactcgagga ggagtttcta tttgctctca tacaggacca gatatattgg
    17341 ctataagttg ttctaattag tagtaatata aggtttttgc atatatatgt gaagataatt
    17401 ttatattgtt aatttatagt atttttgata atatagtaaa tagagtgata tacgtgtttt
    17461 ttaataagag gaggacaagc attaatgttt gaacataaaa tatttaaaat ggattttgca
    17521 ggaagagaac tttctgtaga aataggaaag atttgtgaaa tggctagtgg tagttgtata
    17581 gttcgataca gtgatagtat ggtaatggta aatacaacta aatcagccaa acctagagac
    17641 ggaatagact tttttccttt aagtgtggat tatgaagaaa aattatactc tgtaggtaag
    17701 atacctggag gttttttaaa gagagaaggc aagccttcag agaaagctat acttacatca
    17761 agattgatag atagaccaat aagaccttta ttcccaaaag gatttagaaa tgatgttcag
    17821 gtagttgcaa cagttctatc agtagaccaa gattgtacac cagatatagt agcaatgata
    17881 ggttcttcaa tagccctttc tatatcagac ataccattta atggaccaac aggttcagta
    17941 tgtgttggcc ttgtagatgg tgcatttgtt gtaaatccaa acgcagagca aagagaaaaa
    18001 agttcaatgc atctagttgt ttcaggtaca aaggaagcaa taatgatggt tgaagccgga
    18061 gctgatgaag ttccagatga ggtaatgctt gatgctattt tatttgctca ccaagaaata
    18121 aaaaaaatag ttgagtttat agaaggtata gttgcagaag ttggaaaaga aaaaatgcct
    18181 gttgaattat accatgcagg agaagaaata actcaattgg ttcgcgaatt tgcaactgat
    18241 aagatgaaaa aagcagttca gacttttgaa aagttagaga gaatggaaaa tatggataga
    18301 gttaaagaag aaactttagc tcactttgaa gaaactttag aagattttga agattttgtt
    18361 ggagatatag aagaagtatt acaagatata ataaaagaag aagtaagaaa acttatagta
    18421 catgaaaatg taagaccaga taatagaaaa cttgaagaaa taagacctat atggtgtgaa
    18481 actggcatga tacctagagc tcatggttca gccatattta ctagaggaca aactcaagta
    18541 cttaatgttg ctactttagg tgctttagga gatgttcaaa aactagatgg gttagatgaa
    18601 gaagaaaaca agagatatat gcatcattat aatttccctg catatagtgt tggagaagct
    18661 agaccatcaa gaggtccagg aagaagagaa ataggacatg gtgctttagc agaaagagct
    18721 ttattaccag taataccatc tcaagaagaa tttccttatg ctattagatt agtttctgaa
    18781 gtattaagtt caaatggttc tacatctcaa gcaagtgtat gtggttcaac attatcttta
    18841 cttgatgcag gtgtacctat aaaagatatg gttgcaggta tagcaatggg acttataaag
    18901 catgatggta aggttgcagt gctttcagat atacaaggta tggaagacca tttaggcgat
    18961 atggacttta aagtagctgg aacagagtat ggtataacag caatacaaat ggatataaaa
    19021 attgatggta tagataaaga aattctacaa cgtgctttaa aacaagctaa agagggtaga
    19081 atccatatac taggagagat gagaaaaact atatctcagc caaaaccaga actttcacca
    19141 tatgcaccta agattgttaa aatgcaaata aatcctgaca agataaaaga tgtaatagga
    19201 cctggtggaa agataataac taagataata gacgaaactg gagttaagat agatattgaa
    19261 caaactgggg aagtatttat atcaggtatt gagattgata tgattaagaa agctcaagaa
    19321 cttataaata atatagtagt tgaaccagaa gtaggaaaaa cttataaagg taaggtaagt
    19381 agaataatga actttggagc atttgttgag atacttccag gaaaagaagg attacttcat
    19441 atatctcata tagctcatga aagagttgcc aaagttgaag atgtattgaa tataggggat
    19501 gaagttgaag ttaaagttac agagattgat gaaaaaggaa gagttaattt atcaagaaaa
    19561 gttcttttac caaaaccaga acataaaaat aaataactta ttatataatt aaaagcaaag
    19621 tcttaggatt ttgctttttt aaatacaaaa aagtagataa ttttaaaatg atagttatgg
    19681 atggcttata gttctttttc tgtcagtctt tactcttata aagaagctat ttaaaagctg
    19741 attaatagaa agctttattg atatatatag aatcacttaa gttatattta gtgcataaac
    19801 agagcttatt tttaatagta ttaaataaga aacaatttgt acataattag ggggagtttt
    19861 aatgataatg atggtactta ataagagtaa gctcaaaaaa atcataatac taattttagt
    19921 agtgttatta gtattatcag gaggggtaat ggtattaaag ttatttaaca acaagccagt
    19981 atttaattta tttaatggtg tagatttacc atatgaaaga ggtacaaagg ataaaagtgg
    20041 atatgttgca ttaacctgta atatagacct tggatgggaa acagagtacg tagaatccat
    20101 tttagaaaca cttaaaaaag aaaatgtaaa gattacattt aatgtaactg gaaaatgggc
    20161 agaaaagaat aaggatgaat tattaaagat aaaaaaacaa ggacatgaaa taggtaatca
    20221 tggatataaa catttagatt attctacatt atcatatgaa gacaattatg agcaaataga
    20281 gacctctaaa aagataattg aagaaattat aggtgaaaaa actaaatttt ttcaagcacc
    20341 agcaggttcc tttggtccag aaacagtaaa ggctgctaaa gcattagggt atacttctat
    20401 caaatgggat gccgatacta tagattggaa atacaaagac caaccagagg taatcattga
    20461 tagaatgaag aaaaaagaca ttaaagatag tagtataatc ttaatgcatc caaccaacgc
    20521 aacgacaaaa tgtatagatg atattatagc tattgtaaga gaaaaaggac taaaagcagg
    20581 aaaacttagt gatgtattta agtagacaaa gtataaatat ttggttaaga ttgtataagt
    20641 tgtagttgaa ttaattaaaa gactgactta taatgtaata catataaaaa ataaatataa
    20701 ttaaaacata gtgttttcaa taatccaata tgaaacaaag aataaattgt taggagaatg
    20761 taatgtataa gacaaaaata ctggaaaatg ggcttacaat aattggtgaa gaaataccat
    20821 atctaaagtc aataacatta ggtatttgga taaatgcagg ctctaggata gaagaagcac
    20881 aggtgagtgg aacttctcat tttatagagc atatgatgtt taaaggaacc aaaaacagaa
    20941 catcaaaaga gattgctagt tcaatagata atttgggtgg tcaaataaat gcatttacaa
    21001 gtaaagaatg tacatgttat tatgtaaaac taatagatga gcatatagat acaggaattg
    21061 atgtattgag tgatatgata ctaaattcta aatttgataa aaatgatata gataaggaaa
    21121 gacttataat attggaagaa cttaagatgt atgaagactc tccagatgac ttatcttatg
    21181 atttattagt ggaaaatata tatgctaatg atggattagg aatgaatata attgggacaa
    21241 aagaatctct atacaatata actagagaat ccatgttaga atacttaaat aagtattata
    21301 ttccaaataa cgctgttatt tctatagctg gaaactttaa ctttgatgat atggtggaga
    21361 aaatcaaatc aaaatttgga cactgggaaa agaaaaattt gagtatagac ataagtgagg
    21421 ctaagtttaa tccttgcttt atatcaaaaa ataaagatac tgaacaggtg aacttagcta
    21481 tgtgcctaaa aggtattcct tttgaaaatg atgaagaagt ctattcaatg gcagtggtaa
    21541 ataatatttt cggtggaagt ataagctcaa ggctttttca gaaaataagg gaagaaaaag
    21601 gtttagtata ttcaatatac tcatcacaga cattatatag gaaatgtggt gaattaggta
    21661 tatttgcaag catgagtaca gaaaatttac aagatgtata taatttaata aagaaagaaa
    21721 ttgaaaatat aagagaaaac tatcttacag aaaaagaaat atctgaaagc aaggaacagt
    21781 taaaaggaaa ttatatattg gatttagaaa gtactagcag tagaatgatg tctactggta
    21841 aatctatgtt acttagtaaa aaagtaaaaa ctacagatga aatacttgaa tgtataaata
    21901 gtgttaatat taattcaata aagaaggttg ttgataaggt attcaatatc gaaaatattg
    21961 gtacatgtat agttggaaga gatgtagaaa agattctaca cttggattaa tattgaaaaa
    22021 agtaaatctc tggaggtata aaatatgaat ttatctgaaa tagcaggtaa ggaaatagtt
    22081 aacttggtca caggagaaag attgggggtc attggagaat gtgaccttat actagatgaa
    22141 actacaggcg gtatattagc gcttctaatt ccaaaagaaa aaggattttt tgccagaaga
    22201 aaagataagt catttttaga agtaccatgg agaaatgtaa aaaaaatagg taatgacatg
    22261 ataattatag aatatgaggg atatatttag gaggaaaaaa tgagtatttt agtgcaaaag
    22321 tttggtggga catcagtaga atcatatgaa aaaatgaatg aagtatgtaa gatagtaaaa
    22381 gcatacaaaa aaaatgatga agaattacaa ttagtattag tagtttcagc aatgggaaga
    22441 aaaggagctc catatgctac agatacactt ataaatttgt gtagtgcagt aaatgatgag
    22501 ccaagtaaaa gagaacttga tttaataatg tcttgtggag aaataatatc aggaacaatt
    22561 cttgctaatt tattgaatgc acaagggata gattctgttt tctttactgg tcagcaagca
    22621 ggtataatta caagtgatga atattctaat gcaaagataa agtatataaa tcctaaaaag
    22681 gtaaaaagag ctttagatga tggtaaggtt gtagttatag ctgggttcca gggtgtaaca
    22741 gatgatggag aaataactac tcttggaaga ggcggaagcg atacatcagc agttgctatt
    22801 ggtaaagctt tagaatgtga aacagttgaa atttacactg atgtggatgg tataatgact
    22861 gcagacccta gagtagaacc aaacgctaaa gtattgagtt ttatagacta tgaggaagta
    22921 ttccaaatgg ctgacaaagg tgcaaaagta atacatccaa gagcagtaca gttggctaaa
    22981 agtggaaata taactttagc cataaagaat acaatgaatc caacttttga aggtacaaaa
    23041 ataggttctt tatgtagaca cttagaagac aatatagaat atgaacaaga aagagatttt
    23101 aaggttgctg ttgcaaataa agatagcgta gcacaagtta agattaagtc agcagaagaa
    23161 gtgtttacag aagtattaaa tgagatagaa aagaaactta taactataga tatgataaat
    23221 ttctttatat cagaaaaagc atttgttgta gaagatgctg atataaaatc attaaaggaa
    23281 atactagata aatttgaatt agattatgaa gtaaatagag actgtgctaa ggtaacattg
    23341 atatgttcaa gaattgctga tgaaatgtct ggtatcatgt caaaggtagt tagaggatta
    23401 tcaaaagcag gggtatccct tttacaaaca tcagactcaa atatgactat atcttgttta
    23461 gttagtgaag aagatatgca tacagcagta catgctatac atcaacaatt ttatttaaaa
    23521 taaactgtat aatacaatta ttttttaatc aaatttaaga atttcatata tatcttaata
    23581 tatttgattt atttggtaaa actaaattaa atataatttt gataggagtt tttttatgaa
    23641 agattataga gaagataatg aaagatttga taaagataat tgtagtgaag aatctagttg
    23701 cgaagagaga gaatgtataa agcaatttgg taccaatgaa atgccacctc aacctcctaa
    23761 agatattcaa tgtataacta taattggaga aattgaggga cattttatag gaaatcctca
    23821 aaaaaaagct acaaagtacg agcatataat tccaatgcta tactcaattg aggaaagtaa
    23881 tgatgttaaa ggagtgttag ttgttttaaa cactgttgga ggagatattg aagcaggttt
    23941 agctattgca gaacttttaa acagtacatc taaaaaagta gttactcttg ttctaggagg
    24001 aagtcatagt ataggtgttc ctcttgctac agcaggagat tactcattta tagcaccaac
    24061 agcaaccatg attatacatc cagtgcgaac tactggtctt gtgattggga taaatgagac
    24121 ttttgagtat tttaaaaaga tgcaagatag aataattcaa tttataataa gaacatcaaa
    24181 tatcaaaaaa gatgtacttg aaaaacttat gcatgaaaaa gatgaacttg taagtgatgt
    24241 tggtagtgta ttaataggaa aagaagctgt ggattatggt cttatagatg aagttggagg
    24301 actaaaagaa gcacttaaaa aattaagaga gcttataaaa gaatctgagg aagaaaaaaa
    24361 taatgattaa aatttgttta aataataaaa tttatgatat aatgatgtaa taaagtagga
    24421 gtgttagtgt taaggcatta gcactttttg ctgtgaaggg gtaaaacttg ctaaaaataa
    24481 ggagtgatat taatggccac gaaaaagaag aaaaaaaaga aggtaaatac cttaagtttt
    24541 aatgcagaat atcataattt aataacaata tttataggtg tatttttatt atatagttta
    24601 aattctaatt ctatgggatg gatacctgtg ttaatgcaaa atctttttaa gggactattt
    24661 ggagggcttt caatagcaat accatttata gtaattataa caggactttt aggatttttt
    24721 gatggaaatg aatatatata taggctaaga aagactaaac tatactacat aattatttta
    24781 tttatatttg tattttatgg attattaaat gcaggaactc ttcctgtaga tagcccacta
    24841 aaaggtaaca tgtttgatga tgttatgaaa ttgggtgtaa gtggacaagg tagtggtttg
    24901 atagcaacaa ctattgcgta ttatatgagt aaaatatttg gtatagcagg tggatggtta
    24961 ataagtatct tcgcacttat actttctgta atgtttatat ttaatatttc tataaaagat
    25021 ttggtgtcaa atgcaaaatc aaaatctaaa gcatctaaag acagcaattt aacgtttaaa
    25081 gataaaattg caaatatgaa aaaatctgca atagatatga tgactgatga agtagatgat
    25141 actactataa ataaaaaacc aggtttcttt aaagggttaa tgtcaaaagg tcttaataat
    25201 gatgatgaag aagatgaata ttttgaagaa gaaaatagtg atggtgtaga tgataaaact
    25261 ataaaaatag ttggatttaa taaggcagaa gatgagtatt tagaaatatt agaaggaact
    25321 caaagtatgc cagagttaga tgttttaaaa gaattacaaa aagctaccaa tgaaaatcca
    25381 gttgtagata ctaaaccaga aaaaaaagtt gatatagcta aacctaattt aaatatagaa
    25441 aaaactcaac ctatgagtat tgtagcagag ccagttaatg aggattattc aaactataaa
    25501 aagcctagca ttgagctttt aaataaagta aataagaagt ctgatgaaaa tggtaaaaag
    25561 aaagtgttga aaaatgcttc tcttttagaa aagacactat cagattttgg agtggaagca
    25621 aaaattaatc aagttacagt tggacctact ataacaagat atgaaataca accaagtcca
    25681 ggagtcaagg taagtaaaat tgtaaattta actgatgata tagctttaag tttagcagct
    25741 aaaagtataa gaattgaagc cccaattcct ggtaaaagtg caattggaat agaagttcca
    25801 aatgaagaag ctcaaatggt tggtgtgaga gaagttctag aaagtgaaga atttaataat
    25861 tttaactctc ctcttgcaat gggacttgga aaagacgtag caggaaaaat tataattgga
    25921 gatataggta agatgccaca cttactaata gctggttcta caggttcagg aaagagtgtg
    25981 tgtgtaaata cattaataag tagtatttta tataaggcaa atcctgatga agtaaaatta
    26041 ctattaatag acccaaaagt agttgaactt gcaaattata atggaatacc acatctattg
    26101 ataccagtag ttactgaccc taaaaaagct gcaaatgctt taaattgggc agttacagag
    26161 atgaatagaa ggtacaaatt atttgcagat gctcaagtaa aagatgtaac aagttataat
    26221 gagaaagcgg aagaaaaact tcctaaaata gtaataataa tagatgagtt agcagattta
    26281 atgatggcaa gtgcaaatga tgtagaagat tatatttgta gattagctca aatggcaaga
    26341 gctgctggaa tgcacttgat tgtagcaact caaagaccat ctgttgacgt tataacaggg
    26401 gtaataaagg ctaatatacc atctagaata gcatttgcag tatcatctca aactgattca
    26461 agaacaatcc ttgatatggg tggtgcagag aagcttctag gtaaaggtga tatgttattc
    26521 tatccacttg gtgcagcaaa accagttaga cttcaagggg cattcatatc agagagtgag
    26581 tcggaaaaag taatcgattt tgtaaaaagt caagttaaag atggaataaa atatgaagaa
    26641 gatataattg aaactatatc taaggttaat acttcaaagg gtagtgatga ggatgagttt
    26701 ttgagtgaag cgatagaatt tgtcgtggaa agtggtcaag catctgcctc tatgctacag
    26761 agaagattta aaataggatt caatagagca gctagactta tagattctat ggaagaaaga
    26821 ggaataattg gagcaagtga gggaagtaaa ccgagaaagg tattaataag caaacaggat
    26881 ttgcagaatt tagaaggtga atagaattgt cagttataaa aatagaaaaa gcacttaagc
    26941 tagataaagt aatatttgta gatgtgagaa ctgaaggaga atatgaagaa gaccatatat
    27001 tgaatgcaat caatatgcct ctttttaaaa ataatgaaca taatgacgtt ggaacaattt
    27061 ataagatgca gggaaaacat gaagcaatac aaaaagggtt tgactatgta tcgtataaat
    27121 taaaggatat atatttacaa gcagcagaac ttgcattaaa ttatgataat attgtcatat
    27181 attgtgcaag aggcggaatg agaagtggca gtatagtaaa tttattatca tcattaggtg
    27241 taaatgtata tcaacttgaa ggtggatata aggcttatag aaattttgta ttagagtatc
    27301 taaggcatgt aatggataca aaaaactttg tatctgttca tggattgact ggtacaggaa
    27361 agactgattt gttacattta ttagatgaaa aaggaataga tgtactggat ttagaaggca
    27421 tagctaaaaa cagtggttct acctttggtt ttataacttt tgataaaaag ccaccttctc
    27481 aaaagaactt tgaaacaaaa ctatttgaaa gtatattttt ttcgaaagag aattatatat
    27541 ttgtcgagag tgaaagcaaa cgagttggaa gtgttacagt tccaaatgaa attttcgagg
    27601 caatgacacg agaaggacat catatattat tagaatgtga tattgaaaat agagttgata
    27661 gactttgtag agattatatt tatgataaag atgaaggtaa tatattgatt ttaaaagaat
    27721 gtataaacaa gtttagaaaa agattgggta ataaagtagt agatgattat attgatttat
    27781 tagaatcagg tgaatataaa gaacttgtaa aaagatatct tttagaatac tacgacccac
    27841 tttatatgca ttcagtagaa aaatataagt atagtaagat tataaatttt aatgatacac
    27901 aaaaagcttt agaagatgtt atagacttat atgagagtat attggaagga gaaagtgaat
    27961 gttaaaaata gcattagaat cattaggatg ctcaaaaaat ttagtagatg cagaaataat
    28021 gatgggaatt ttaaataaca aaggctataa attaattgga gattttgaag aagctgatgt
    28081 aattatagta aatacatgtg gatttataga gtcagctaaa caagaatcta tagatacgat
    28141 aataaacttt gcagagttaa aaaaaactgg caatttaaag ttgttgatag taacagggtg
    28201 tctagcccaa agatattctg aagaattaaa aactgaaatt cctgaaatag atgctatagt
    28261 aggaacagga agctatcaaa atatagataa aatacttaaa gaattaagtg aaatgcataa
    28321 aattgtaagc cttaatgata tagagtttgt atttaatgaa gatttaccaa gatatatatc
    28381 tacacctagc tatatggcct atttaaaaat tggagaagga tgttccaata attgtactta
    28441 ttgtataata ccaaaactaa gaggtaaata tagaagtaga aaatttgaag atataattaa
    28501 agaagctaag aaattagctg aatctggagt aaaagaactt gtggttatag cacaggatac
    28561 gacaaagtac ggttttgatt tatatggaaa agaaagatta tcagaacttt tagaagaact
    28621 tgcaaaaata gatggattta agtggataag ggttatgtat tcatatccag aatctataac
    28681 agaagaattg atacaagtta taaagaaata tgataatata tgtagttact ttgatatgcc
    28741 aatacagcat gcaagtaaca atattttaaa attaatgaat agaaaaacta ctaaagaaga
    28801 tatattaaat aaaatcaatc tgataagaag taatatacca gatgctatac ttagaactac
    28861 aataatagta gggtttcctg gtgaaacaga agatgacttc aaacaacttg tggactttgt
    28921 tgaagaggtt aaatttgata gacttggtgc atttgcatat tcaagagaag aagatacacc
    28981 agcagataga ttgccaaacc atatagatga agaagtaaaa atacaaagaa gagatacttt
    29041 aatgatgatt caacaaaaaa tatctgaaga acttaatgac aaaaagatag gaaaaactta
    29101 tgaggtgtta atagaagaac agatagaaga taatgtatat acaggaagaa cacaaggtga
    29161 tgcagaggaa attgacagta tagtgtatgt aaaaagtgta gacaatcttg aagtaggaga
    29221 atttgtaagt gttcaaataa atgatgcaat ggaatacgat ttaatgggag atgttttata
    29281 tgaacttgcc taacaagtta actttgttta gaatattttt aataccagta tttgttttaa
    29341 ttatgttgct caatatacca aataaatttt taatagcttg tattattttt ataatagctt
    29401 caattactga tgctttagat ggaaaaatag ctagaaaata caatctagtc actgactttg
    29461 gaaaatttat ggacccatta gcagataagt tattggttat ttcagcactt acatgtatga
    29521 tagaagacca tcttgtaagt agttggatgg taattataat agtggctaga gagcttacag
    29581 ttagcatatt aagagctata gctgctgctg atggaaaagt aattgctgct ggaaacagtg
    29641 gaaaacttaa aacgataact caaatggtat ctatagtgtt tttattgtta ggtgctcagt
    29701 ttgaaaatgt attgatatta aatattggtg aaattctcat tcttatagct acactactta
    29761 cattatattc tggatgggaa tatctatata aaaataaaga gctttttatg tcttctaagt
    29821 aaaaaattat gctttaataa ataaaaacta atgattaata aataaaaaat aacaacttaa
    29881 aattttaaaa atgtaaaaaa gggtatacta ttatagtata cctcttttca ttttaagaat
    29941 attttctttt gtgtatataa ttattaataa tggtttataa ataaaatgta atgaataaaa
    30001 atataatcat tagtagcgtt tttaaattga ctaggtttga tttatgttat ataattaata
    30061 tataacaaga gaacaaatgt ttgtagataa atgaagggat ggtatagaga tgagtgtaga
    30121 tcaagaaaaa ttaaaagcgt tgaatgaagc tttaggtaaa attgaaaaag attttggtaa
    30181 aggttcagta atgaaattgg gagaagcaac atctatgtct atagatgtta tatcaacagg
    30241 agcgattggt ttagacatag ctattggtat aggaggtcta cctagaggga gaatagttga
    30301 agtatatggt ccagaatctt ctggtaagac tactgttgcg cttagttgtg tagcatcagc
    30361 tcaaaaagat ggaggaatag ctgcatttat agatgcagaa catgcacttg acccagtata
    30421 tgcaaaagct ttgggtgtgg atgttgataa cctaataata tctcaaccag atacaggtga
    30481 acaggcttta gagatagcag aggcattgat aagaagtgga gcgatagata taatagtaat
    30541 agactcagta gcagcattag ttccaaaggc tgaaatagat ggagatatgg gtgattctca
    30601 tgtaggttta caagctagac ttatgtcaca agcacttaga aagttaactg gttcaattaa
    30661 aaaatcaaat tgtgttgcta tatttataaa ccagttaaga gagaaagtag gaataatgtt
    30721 tggaaaccca gaaactacta ctggaggacg tgcactaaaa ttctattcat cagttagatt
    30781 ggatgttaga aaaatagata caataaaaca aggtgataaa gttataggta gtagaactag
    30841 agttaaagtt gttaaaaaca aagtagcacc accatttaag caagctgaat ttgatataat
    30901 gtatggagaa gggatttcaa aaattggaga ccttttagat atagctgctg atgtagatat
    30961 agttaaaaaa tcaggttcat ggtatagtta caatgatact aaacttggac aaggaagaga
    31021 aaatgttaaa aaattcttgg aagataattt agatttaact actgaaatag atgagaaagt
    31081 tagagcattt tacaatttaa atgaagaaca tgaagaatca ggtacttcag tatcaaaaga
    31141 aattgtagaa gaataagtaa aaatacaaaa aaataactag taattaaaga catgccacgc
    31201 tccctattag cttgacacaa tgttgaaaaa attataaaat taagtgagga taaaatatct
    31261 aaatttaatt ttaattatta ggaatatttt ttaatcatag tgatgacatt ttgggattat
    31321 taacgaagga ggtggatgtc atagatagtg tagtaatgat tgtaataggt gcagctgttg
    31381 gtattatagc tggatatttt gttagaaaaa atatatctga agcaaaaatt ggacaagctg
    31441 aaaacttggc caaagaaata atagataaag cacaccacga ctcagaaaca gtacaaaaag
    31501 aaaaattact agaagctaaa gaagagatcc ataagtggag aacagaagct gaaagagaaa
    31561 acagagaaag aagaacagaa gtacaaaagt atgaaaaaag agtagtacaa aaagaagaag
    31621 tcttagatag aaaattacaa aatttagaat ctaaagaagt aaacctaagt gaaaaattaa
    31681 aggtagtgga aaagaaagaa gaagaagttg aagtaataaa aactcaacag ttagaaaaat
    31741 tagaaagtat atcaggaatt acttctgata aggccaaaga aatcatctta accaatgcgg
    31801 agagagatgt aagacgtgaa atgtctataa tgataaaaga gatagaaagt caagctaaag
    31861 aagaagctga taagaaatca agagaaatta taggatatgc aattcaaaaa tgtgcagcag
    31921 atcacgtagc cgaaactact gtaacagtag taagcttgcc taatgatgaa atgaaaggta
    31981 gaataatagg tagggaaggt agaaatataa ggactttaga aaccttaaca ggtatagacc
    32041 ttataataga tgacactcca gaagccgtaa ttttatcagg atttgatcca ataagaagag
    32101 aaattgcaag aattgctcta gaaaaattaa tagcagatgg aagaatacat ccagctagaa
    32161 ttgaagaaat ggttgaaaag gcgagaaaag aagttgacaa tattataaaa gaatatggtg
    32221 aacaagctgc atttgaaact agtgtacatg ggattcatcc ggaattaata agattattag
    32281 gtagacttaa ctatagaact agttatggac aaaatgtact taaacattct atagaagttg
    32341 ctcatatagc tggtataatg gctgctgaaa taggagcaga tattagattg gctaagaggg
    32401 caggtttatt acatgatata ggtaaggctg tagaccatga aatggaaggt acacatgttg
    32461 aaataggtat ggatttactt agacgttata aagagtctaa agaagttata catgccatga
    32521 gtactcatca tggagattac gagcctcaaa cagtagaggc tgtattagtt acagcagcag
    32581 atgcaatatc agctgctaga cctggtgcga gaagagaaac tttagaagca tatataaaga
    32641 gacttgaaaa attagaagaa atagctaatt catatgaagg tgtagaaaaa tcatttgcta
    32701 tacaagctgg tagagaaata agaataatgg taaaaccaga agctataaat gatgaagaaa
    32761 tacatctatt ggctagagat atgactaaga aaatagagga tgaacttgaa tatcctggac
    32821 aaataaaagt aagcataata agagaaacaa gagctataga gtatgcgaag taaaagaaat
    32881 aatatctaaa taataagaaa atatttttag aaatttaaat ttgccacaag atatgataat
    32941 atatcttgtg gcttttaaat tgtttaagtt taattttata taatgcaaaa ataatctaag
    33001 tgctaaaagt gctacttaca aaagattaat aaaataaagc tttatatatg tattatttat
    33061 ataattatcc aagtttgttt gatataatga agttgtaaaa taaatatatt actacttgga
    33121 atgcttgtac ttaaataaga tgaaaataca atgacgctaa agtgaggatt agagagaggg
    33181 tacactatga aaaaaaatac acttttacat acaaatatta tggtttgcat tattattact
    33241 cttggttttg tggctacctc tataattgga tatcaatcta ataccaatat ttttaaaaat
    33301 gatattgaac atgtatctac attggctgct gaaggtattt attatcagat agataaacta
    33361 ctttcagaac ctataaatgt atctcttaca atggcaaatg acagtctatt aaaaaatttt
    33421 ttagatggtg agaaagaaca tttaaatgat gaagaattta tttataaatt acaagattat
    33481 ctgaatgtgt atagaaataa atattcatat gattctgttt ttttagtatc aactaaaacc
    33541 aataattatt atcattttaa tggacttgat agaaatctta gcgctaataa ctcagagaat
    33601 caatggtatt atactttctt aaagaatgat gatgaatact cattaaatgt tgataatgat
    33661 gaagcaagta acaatagtat tacagtcttt gtaaattgta agataaaaga tgataatgga
    33721 gcaactatgg gaattatagg tgttgggtta aaggttaatt cattacaaat gttgcttaaa
    33781 ggatataatg acaaatttga tgttgttgca cgcttaattg atgataaagg gtttgtacaa
    33841 ttagcagtag ataaaaccgg tcatgagaat ataaattttt ttgaaaattc tagtagcgac
    33901 ttgtctaatt cgaaacaatt aatattaaac aacaaaaagg aacaaaagag tttttggtat
    33961 tcatctgaaa aatcaaaaag ttatattgta tgtcagtaca tacctagttt aaaatggcat
    34021 cttgttctag aaaatgattt tactttaatg attaaacagc ttcatctgca attttttaaa
    34081 ggcattgcag ttatagtttt aattataata tttgtacttt ttactattac acatgtgctt
    34141 aaaaaataca aaaaccaaat aataaagctt agtgtttcac agaaattgga atatcaaaaa
    34201 ttgttgagca aatctactga aggtctttat gaaaatattt ttgaaattga tattactaac
    34261 aataaagctg gttgtgaaga tgagaatagg tattttcatg aatttggatt agggcttaat
    34321 accccatatg atgaagcctt acatacaata gctaaaaacc aaatcaaaga agaatatgca
    34381 caaggttatt tagatacatt tttacctgaa aatgtaatta aacgttataa tagcggaatt
    34441 aataatatca gctatgattt tttaattaaa aaagatgaag aaagttatca ttggattaga
    34501 attaatgcac gaattttctt ttggacatca gatgaatctg ttcgtatgat atcttatcgt
    34561 aaaaatatag atgaagaaaa aaatagagaa ttactacttc tcgaacgttc acaacgtgat
    34621 tctcttacag ggctttacaa taaagctaca acagaggaat ttattcgttc atttttaaaa
    34681 aatgaaagta atcaagattt agaacacgtt tttctaattt tcgatattga taattttaaa
    34741 aatgtaaatg ataaatatgg tcatgtattt ggagactttg ttataagtga atttgcctta
    34801 gaattaaaat ctcaatttcg tgaggacgat attgtgggac gtattggtgg agatgagttt
    34861 gtagtattaa taaaagactt taataataat aactatgtgc ttatagacaa attagagcgt
    34921 ttttgttcta agattaatca gaaaaaattt gttgagcaag cagaattttc tattgcatgt
    34981 agtattggtg tagcaatgta tcctgaacat ggatatgtat actctgaact atatgagaaa
    35041 gcagaccaag cactttacta tgcaaaaagc catgggaaaa attcttatca tatattttca
    35101 gaggattcta ttgatagtat ttcatttcat atagactcta gagatataaa agtattatta
    35161 gaaatggcta ctgatggtgt tgtcaaattt gcttgtatgg aaaacttaaa attactttat
    35221 ttcaaccaaa aaatgcttga atttactgga tattcagctc aaactgttac ttctataggt
    35281 tttgatattt tttcgcctgt attacaagac gacttacaaa tggtactaga tacattaaga
    35341 gaagcaattt ctaaaagaga gacttttgaa atagtttttc gtttttgtca tacagatggt
    35401 catatttttc ctgtaaggat gcaaggtaag tttgtaagtg aattatatca aaatcgttat
    35461 cctgtttttt atgcgattta tacagacata tcaagtatca atactttact agaaaataaa
    35521 tagtaaatac tacagtaaaa tctaaaaata ggatataata gtattaatat aagaagatta
    35581 taaataaaac ctgctaatga aaatagatta tttttagcag gtttttaaat tttttataat
    35641 aaatcttatt tttggctaac aagatttatt ttttttaaga ctttacttat tattttaagc
    35701 attaattatg aaatttatca ttttattatt tacagaaagt attttataac aataaatatc
    35761 tatacttatt gcaaaatttt tttagcagtt ttgtatttat ttgtatttat tttgaattta
    35821 tttactaaat ttgcctataa aaagtatata taaaaatata gttcaaaatg gtataattaa
    35881 gtataacaga aggaggtaat gtaagtgagc caatacataa atataaattc tcagttagac
    35941 gccctaaaat tgaaggagtt cgagaaaata ttttacgaaa atatcaatga ggacgttaaa
    36001 gtagtgccaa aagttactcc ttttaaagga ataaataccg atttgttgta tgttaaagat
    36061 ggaagaattt tatttataaa atttatggat acaacagaag atatattttt tattttagaa
    36121 gaagagttac ttgaagttat gaatgaggaa tatgaacttt tgaaactaaa aatgggacaa
    36181 aagaatagaa atataagtta taactacgtt tacattatgc catacgttga agttgaggaa
    36241 acatatgaat ttgaagaatt tgttaataat aatataatag ataaaaataa gcttcaagat
    36301 ataatgaata agggttcgct ggaggaatat cttaatgatg agaatgatga aataaactta
    36361 aatttatttt tactagacat atgttcagaa tactatataa taaatgataa acttcatcta
    36421 aatgaaaaat ttaaaaaaat ttcattctac aatgatgact ataagtatac agcaactatg
    36481 atggaagacg ttcaaattaa agatgttgtt tctattaaat atgggaatac acttattgaa
    36541 ggtggttctg gtataggcaa aacagcaatt atgctttcta gggctataaa attagcaaaa
    36601 gtatatccac atcataaatt agtcatattt acacatacaa aacaactgtg caatgagctt
    36661 cgagagagga tagagttatt atacaaagat aataacaatt tagaagttca cacatttagt
    36721 tcttttatat ttaaactagc taaaaaattc aatttaattg tagattataa catgttaaaa
    36781 aatgattacg aaaagacctt taataatctt gtaaaacaag cacagaacat tataaaaaat
    36841 aaaaatatgt tcaaggctat ttttattgat gaagcagaaa gctttttaga gtatgaaata
    36901 gattttataa gggagttttt atataaaaca aaattcatat ttaatgtgtg ttcttgtaac
    36961 tccttgaata tctctaatag attgaatata tttaaaaaat tatataatgg tatagaattt
    37021 gatgataaga ttatcttaag taaaaattat agacaagcta aagagattgt agattttaca
    37081 aataaatttt caaataattc taactcatat atcaacgaat taagaccaaa tacagaattt
    37141 agtactttct tttatactaa agcacttaga ggtggaaata agtctgttga tataataaaa
    37201 gtaagtgacc ttgatgacca aataagttct gtaatctggg aaattgagta tttaataagt
    37261 aaaaaaggtc ttgattattc tgaagttgct atcgtttatc cttacaataa gaagaaatta
    37321 aaaagtggaa aaaccattta ctttcaatat atgttaaaaa aagcattgga agaggcaaaa
    37381 attccttata tatgtgcaga agataatttg acaaatataa gtaagaaggt aggaactaca
    37441 atagcaaata tatatgcaat aaagaattta gagtataaag cggtaatagt atgtgaatta
    37501 gagatgttat acaatcaaac tataaatgat attgaacaag attatcaagt aaatgacttt
    37561 gtaggagatt taaataaggt ttatttagct atgagtagag caacagacta cctaagtata
    37621 gtaacaactt ttaatgaaga agcaagtgat ataataagac ttattacaga atcaaaagat
    37681 atttagtaaa aaaatatttg taatttaaga aaataaaaag agactgagat ttgtaaaata
    37741 aactttacca attcagtctc ttatttttta gtctactttc ccaatattat caagaggtaa
    37801 tagtctcacc ataaccttac caagaacttc atcttcatca accataccta catcagggaa
    37861 tctactatca ttactatttt ctctattatc tcccattgca aatagtttac cttttggaac
    37921 aacagtatct atatctccag aagtatagtt attgtgtata tatggttcat ttaataattt
    37981 tccatttaca tacactttag aatttgatat ttttattctg tcaccttcag tagctataac
    38041 tctttttatt aagtcttttt tctttcctgt ttctccatca actaaattgg ttttaaaaac
    38101 tacaatatcg cctttttcag gtttaccaac cttgtatgat atcctattta aaatcagata
    38161 atctttatca tctaaagtag gatacattga ttctccactt acaatagaag gtcttataaa
    38221 ttgtagaatt acaaatgcaa gtacaatagc catagctatt gacttaatcc aatcaaatat
    38281 ttctttttta acactcataa cttttctcct tatcatttgt tattaaatta gaatacatta
    38341 taatagaaag aaataagcaa gaaccactat acccaagact attctataat aaccaaatac
    38401 tttgaagtca tgttttttga tatagtccat aaaaaattta ataactacaa ttgaaacaac
    38461 aaatgctact acagaaccaa cacctaaaat aagccattca aatccagtaa atccaaatcc
    38521 agcttttaga agttttaatg cactagctcc aagcattgta gggatggcta agaagaatga
    38581 aaactctgct gctacatatc tagaagtacc aagtaatact gcacctatta tagtagaacc
    38641 agacctagat gtacctggta taagagctag acactggaat aatcctatac aaagagctaa
    38701 tttatatgta acttgagaaa aatctttata cttaggtttt ttatttctct tttcaagccc
    38761 tatcattatt ataccatata caataagagc aatagcaact actgttgaat taaagaataa
    38821 tctatctata tcatcttcaa acagtattcc aataactcca gatggtataa ctgcaattat
    38881 aaccttaagc cataaacgga ctgtttcttt tttctgctta atattctttg cgctatcaaa
    38941 aggatttaat tttctaaaaa atataacaag tacagctaat attgaaccaa attgaattac
    39001 aactaaaaat gtacttataa atgtatttga aaaattcaat tttataaact catcaactaa
    39061 tatcatatgc cctgtactac ttactggtag ccattctgtt attccctgaa ctatgcccaa
    39121 aatgactgcc ttaaaaattt caagcaaact aaatgtttcc aaatcaaaat acctccaata
    39181 caaatttata gtagcatatt ttattcatag attaataaaa aaatgccacc ttttactaac
    39241 ttataatacc atagtactgt gtagtgcaca atggaagatt gatattttca taaaaccttc
    39301 ataatataac aaaataaact taaaagttat ctattgaata aggggtatat ttgaggggga
    39361 aatatatggt atagtaaaag tatagctatt ttattttatg aaaaggaaag gagttattat
    39421 gtatagtaca aaaatactag atgattatga gtatgaaact tttaatgttt tttctacaaa
    39481 attaaatcca aacacgaaac acgattattt atcaaaggtt atactgttta aagaattttt
    39541 aaaagggaaa gaattgattt atgctacgaa agaagattgt aaaaattttg tagactatat
    39601 acagactaaa tatgcgaaat caacttgtga aaagatatat agttatttac atagttttta
    39661 taacttctta aaaaaagaag gatacataga tataaatcca tttagatatg tagaaaaacc
    39721 cacagtaaca agaataaaaa caaaagatga tgttctaagt atacaagaaa taaataaact
    39781 tataggtatc ctaccaaaat taaatataag agatagagta ataatagtct gtctagttac
    39841 tactgggtgt ttattaaatg aattagttag cttaaagtgg aaagacctta tggtagatga
    39901 aaacgataac tcatatgtaa ggttaggtaa gggaagaaaa gaaagagtag ttaaattaca
    39961 tccatacttt tttaaacttt tagaagatta caggaattat tctgggcttc cagaggtaat
    40021 aatacctagt gatgatttta tttttacaac tcaaaagagt aattctataa cagatagaaa
    40081 tgtcagactt atagtcaaaa aagcattaga tttagctgga ctttctcaat attcagcaag
    40141 agattttaga cattcatttg cagcaataag tttaaggctt ggggcagatg aaagtgatgt
    40201 aaaaaatcag cttggatgga gtgataaata ctatgcaatt agatataagt atgtattaaa
    40261 ttttgttgat agtgaaatag tggattactt aattgaaaaa gataatttgg atataaataa
    40321 aaaatagtaa taaataaaaa atactatata taaatgtgaa caaaaaataa aaaagtcttg
    40381 ttatagttcg taaaattata tataattatt tatgtactaa tgtgtacaca gtaatcacac
    40441 gacaaaagat ttaaggaagg tgctaatata atgatagata ataaatatac tacttactca
    40501 aacccactta cagacagata ttgtagcaag gacatgagtt atatattttc tccacaattt
    40561 aaattctcta catggagaag gttatgggtt gcacttgcag aaggtgaaca tgagttagga
    40621 atcaatataa ctgaagaaca attagatgag ctaagagcta atatagataa tataaatttt
    40681 gatgaagcta gaaaaataga aaaagaagta agacatgatg taatgtctca cgtaaaagct
    40741 tatggtttac aatgtgaaaa agccaaagga ataatacatt taggagcaac atctgcatat
    40801 gttggagata atacagatgt tatacaaatg aatgaagctt taaaacttct aagagtaaag
    40861 cttgtaaatt taataaacaa tttaaaagaa tttgcactta agtacaaaga tatgccagct
    40921 cttggattta cacacttcca agctgctcaa cttacaacag taggaaaaag agcttgttta
    40981 tgggctcaag atttaattct tgatttggaa gatttaaact atagaataga caacatgaag
    41041 ttaagaggag ttaaaggtac tactggtact caagcaagtt ttttaagctt atttgaagga
    41101 gaccacgaaa aagtaaaaga gttagataag aaaatttgta aaaagatggg ataccattct
    41161 tcctatgcag taagtggaca gacatatact agaaagttag attatcaagt aataagcata
    41221 ctatcaggga tagctcaaag tatgcataag atgactaatg atataagact tttacaaagt
    41281 ttaaaagaat tagaagagcc atttgaaaaa aatcaaatag gttcatcagc aatggcttat
    41341 aagaggaatc caatgagaag tgagagaata gcatctttat ctaagtatat aatctctgaa
    41401 tctataagcc ctgcaatggt acaagccact caatggttag agagaacatt agatgactca
    41461 gccaataaga gattggcaat acctcaagca tttatggcag cagatgctat acttgaaata
    41521 gggataaatg taactgatgg tttagtagta tatgaaaata tgataaatag acgtgtaaat
    41581 gaagaacttc cttttatggc tacagaaaca atacttatgg aagctgtaaa aagaggtgga
    41641 gatagacagg aattgcatga aataataaga gaatattcta tgaaagctgc ctatagagta
    41701 aagcatgaag gcaaggataa taacttaatt gaacttataa tgaatgatga ttcatttaaa
    41761 atgagcaagg aagaaatact atctataatg gacccaaaaa actttatagg tagagctcca
    41821 gaacaagttg tagaatttgt aaatgaagtt gtagaacctg ctataaaaga ttataaggaa
    41881 gacttaggaa aagtagatgt agacctaaga gtatagaatt gtacagataa aatataatta
    41941 aaaacggcta tcttatttat aaataagata gccattttaa tgggctagcg tcttctctcc
    42001 accgctgtga agagttcttc tttacttact ataccatgaa tttaataaaa tagctatata
    42061 aataatattt aataggaata atataaataa aaataaaaaa atgataagat tactaattaa
    42121 atttaaacat tcagcaaaaa ctattgtact tgcaatattt ttaatgtaaa ctgaaataaa
    42181 gttatttaga taatttaata aattttaaaa caaccgaggt gattatatga actatatagt
    42241 aaaagatacc ataagttttt tagtaaaaac atttcctaag atttattcta gcctgtactt
    42301 agaagaccta aaaaaatttg caccagatta taatgtaaat aaaacacaat taagagcatt
    42361 agttttcata aaaaattatg gagtaataag tatgactgat ttatgctcta agttaaatat
    42421 agaaaaaggc agtttaacta gtatggttga tgatttaact gataagaagt atgtaacaag
    42481 gaaaagagat ttagttgata gaagaaaata tctaattgac attactgaag agggagataa
    42541 gatagcaact gattttatgg ataaattaag tgatggttta ggagaaaaac tttctaaatt
    42601 aactgaagaa gacagaaaaa aatatttaga agcaataaat actcttcaat atatattaaa
    42661 caaagaagaa tttagataga aaaaatataa aaatttttgt atttaatggt actaagatta
    42721 attctttgtt attcatttaa ctatataatt ataagtctaa atacaatcta aaaagtacat
    42781 cttaaatttt cttgatgtac ttttttataa tttctctaac taaggcaaga caagttttag
    42841 atgctttaat taaagtgaat aaagattact ggccaacact atataaagaa aatgaaaaat
    42901 agtcaggtct aagtcttaat taatatatta attaagaaat gtcccctttt caaataatat
    42961 ctgaaaaggg gacattttat atcattaaat ttatataaat taagtttaaa aaattatttt
    43021 tgtaaagcta catattgctc taaaccttct tttaataatg tagcagctct atgaaggtct
    43081 ttttcattta agatgtaagc taatcttatt tcatcacgtc ctaaacctgg agtagcatag
    43141 aatccttcag cagggcaaac cataactgtt tcattatctt tattaaattc ttttaacatc
    43201 caaattgtga aatcttctgc attttcaact ggtaatttag caactatata gaaagcacca
    43261 gttggttttt tacatataac accttcaacc ttcattaatt cattgtataa tacatctctt
    43321 ctttttttgt actcttcatt aacttctttg aagtaagaaa caggagtttt gtataactca
    43381 acagctccta tttgctctaa tgtaggaaca caaagtcttc cttgacataa tttaagtatt
    43441 tgagcgataa gacctttatt tttgcaagcg atagaaccaa ttctagcacc acaagcactg
    43501 tatctcttag aaacactgtc tattattata actctatcct gtacaccctc taagttacca
    43561 cagcttgtat actcaagccc atcataaaca aattctctat aaacttcgtc tgctattatc
    43621 cataaatctt tttctttagc tatttcagct aggatattaa gttcttcttt tgtataaatt
    43681 gcaccagttg gatttcctgg gttagaaaga attatagcct tagttttatc atctacttta
    43741 gacaatattt cttctttaga tggaaggtgg aaaccgtttt ctgcctttgt tgtaacagca
    43801 ttaacttcta cgtttacaga ttgaccaaat ccattgtagt ttgtatagaa tggttctgga
    43861 actaatagat tatctcctgg gtcacaaact gccatcatag tgaaaagtaa agcttcacta
    43921 ccaccgttag ttactaataa ttcatctttt tcaaaattca tatcgtaagt tttatagtaa
    43981 ttttgaagtg cttctaataa ttctggaata ccttctgatg tagcatattc taagacttcg
    44041 ctatcaaagt ttttaacagc atcaaaaaat cctttaggag tttttatgtc tggttgtcct
    44101 atgtttaagt gatatacttt gattccttta tcttttgctg cttgtgcaaa tggaacaagt
    44161 tttctgattg gagaggcttg cattgcacta actctgtttg aataattcat tttaataccc
    44221 cctatttaat ttaaatacgt atattgtatt atgtaaattg tatgtttgaa tacaagacat
    44281 ctttacaaga taataataac atacttatgg gtaaaaatca tcaaaaaaaa ttaatatagc
    44341 tttaaaataa acttttaaca aattatagta aaatacccat gtttatgcca ctaaattatg
    44401 tattcataaa ttaatttata gtaagataat attctgatgt actgatagtg attttttagt
    44461 tataatcttt cagctataga caaaatatat aataataaat atgcaaaatt ataaaaaata
    44521 ttataaattt atttaacaga tacgataaat atcatataat tatattaaag gctattaact
    44581 aagaggtgtt aattatgaaa gaattaagaa tagatccaat taccaatgat gttgttatat
    44641 ttgctacaga taggttaaaa agacctttag atacagcaga tatcccaaat gaagatgaag
    44701 aaactaatga atatgatgaa gaatgcccat tttgcaaagg aaatgaagct catgcaactg
    44761 atgcattatt tgaaatagat agtgaagaag gatggcttgt aaaatctgtc tacaataaat
    44821 ttcctataat tgatgatatg gcaagagatg tatatggtgt tcatgaagta atgatagaga
    44881 gcgataaaca taatcgtagt ttttataaca tgagtcaaaa agaatttgaa gatgtttttt
    44941 ttatgtatag aaatagattt agagatttgt cgaaagatga taaagtagag tatgttagta
    45001 tcttcaaaaa cttcttgaga aaggcaggag catctttgat gcatccacat gctcaaatat
    45061 tgtctatgtc ttttattcca cctgaaatta cgaatgaact gttggtttca aaggagtatt
    45121 atgacagcaa taaaagctct ttgtatgatg atttaataga aaatgaaata agtttagata
    45181 gaagagttgt ttataatgga gaagcttttt tggtacttat accatatgca accaagtata
    45241 gtggagaagt aagaataata tttaaagata aaatagagtt tggtgagtta aatgataata
    45301 atatacagga gctttctaca atatttgaaa agttgtttaa gaagttatac aatatcaatg
    45361 gatatatgcc atttaattta tgtattcaca ctcatccaac aaagattgaa acaaaatcgt
    45421 attttaatgt tcatatgcac ataatcccaa gaaaatataa ttttggagga tttgaacttg
    45481 gaacaaatat gtatgtttct tcaatgagcc ctgaagattt aacaaaaaag ttaaaaattg
    45541 attaaaacat atatttttag gtattaagta aatagtaatt ttagatgaaa ttatagtata
    45601 gcattgttaa aataaaagta aattaagaat ttacaataaa attgttgaaa agcccccatc
    45661 tttagctatg gggagtgtgt caatgtttag atgaggagta taagtatgaa atttatatca
    45721 tggaatgtta atggaataag agcttgtgtt gggaaaggat ttttagactt tttcaaagaa
    45781 gtagatgcag atatattttg tttacaagaa actaaattgc aagaagggca aatagagtta
    45841 gatttaccag gatattttca atattggaat tatgctgaga gaaagggtta ttcaggtact
    45901 gctatattta caaaaaaaga gcctttaaaa gtaatgtatg gaataaatat agaagaacat
    45961 gacaaagagg gtagagtgat aactctagag tttgaagatt tttactttgt tacagtatat
    46021 acgccaaatt ctcaatctga attaaagaga ctagaatata gaactagatg ggaagacgac
    46081 tttatagatt atttaaccaa actagataat cataagcctg taattgtgtg tggagatatg
    46141 aacgttgcac ataaagaaat agatttaaaa aatcctaaaa ataatatgaa aaatgcaggt
    46201 tttactaaag aagaaagaga gaagttttct aaattattag acagtgggtt tatagacaca
    46261 tatagatatt ttaatcctga taaagaaggt gtttatagtt ggtggtcgta tagatttaat
    46321 gcaagaaaaa ataatgcagg gtggagaata gattattttt gtgcatccaa aaaattagaa
    46381 gatagattag taagtgcgga tatacacact gaaatattag gttcagacca ttgtccagtt
    46441 gaattagaga taaaataaaa attaattatg ataaaaattg ggctgtagat ataaatttaa
    46501 agttaactag ttttttaatc tacatgccta ttttttatct aaataaactc tatttgtttt
    46561 ttctttgctt aacattttct aatgtaaatt gatttgtttt ccacatatta taagctaagt
    46621 taatgatttt tttctcgtct ttagttaatt cacgatttaa aattttccta aattcatcaa
    46681 ataacttatc ataatcaact ctttttttgt tagaatatct tatagtttta ggttttatac
    46741 tcgtataaag atatatatct gggactatac ttggattgta tatcttaata aaaactttag
    46801 cagtataata tgcatcattt aaagcattgt gataagacat tttttcatca agttccaata
    46861 tagaaatagc attttgtagg ccaatgcttt ttcctgctgg attattgaaa tatttagatg
    46921 catgttgttg tatattaata taagatttag gtaaggaatt tgatggtagc ttgtgatagt
    46981 tgatattcct gtataattcc ttcaaatctc cagctcccca aacacataat atagggtctt
    47041 gtgatgatat aaattttata aaattgttgt agacctcagg gaaagtaggc gaatcattaa
    47101 aatcagaact tttaatatta gtcatacgac taataaaggg atgtatgtct ttataaattg
    47161 taggttttac atagctatta aacgtatcta ttatattgaa tttagaatcc aatttaattg
    47221 ctcctatttg tataatttca aaaggacact tttcattgga tacagtttta ttgagttttt
    47281 tatcaaatcc ttggttaaat tccaaatcga aaattatgta ttccataaag tttatctcct
    47341 aaattttttt attatttctt ttactataga ttatattata aataaaatta aattttcaaa
    47401 taaaaatact tttattttag tataccccat atttgtaaaa atgttaaact attgtatgta
    47461 taatattttt tccaataaaa aatattgcga actttttata cttgatatat aataatataa
    47521 ataaaaacac gaataaaaca cgaataattt gcaagaaaaa ttcataaatg taaggaaaat
    47581 gaaatttatc ttgtatttaa caaaataaaa tatacataaa aattatggga gagtggaaaa
    47641 atggatagtc tattatacgt aatagagaaa gataaacaca ctaatgaaga attaagagaa
    47701 atcctaaaaa gcaataaaaa tataagattt gtttccttaa tgggggttga tttaggagga
    47761 aatgcaacag atgaaaagat tcctgtagaa ttatttttgg aggatataga taaatttttg
    47821 gaatcagcta tacagactga tggttcaagt gttgagcttt ataatatagc tacattaaat
    47881 aatgcgaaag tagatttaat gccagataaa agttgtcatt ggtatgtaga ttacaatatg
    47941 gaatatatag acgaagaagt aggtctacct gttggaacat taaagatacc tgcattttta
    48001 atacatgata ataaaaaagt atgttctaga ggagtacttc aaaaagcaga taagtacttt
    48061 aaaaagtcaa tgtatgaaat atttagagaa tatccacatg taataaataa cataggaata
    48121 gattcagtag atgatataga ggaaataatg ttaacagcag ctacagaact tgagttctgg
    48181 gttaatactc ctgaggataa agctgactta gagaaattat atgtatcaca aagcctaaaa
    48241 gagcaatact ggaaaagaac tcatggtatt ataagaactt gtttagagaa aagtttaatt
    48301 atacttcaaa agctaggtgt aaaccctgaa atggctcaca aagaggtcgg aggaatacaa
    48361 agttctatta gtatagatgg aagaacaaac catgctatgg agcaattaga ggtttcttgg
    48421 aagttttcta caccgttaca agcagcagac aatgaattat tagtaagaga tgttatagag
    48481 gatgtattta catcacatgg actagaagtt acatttaaag caaaaccaat tcatggagta
    48541 gcaggaagtg gtggacatac acatgtagga gtaagtgcga agttaaagga tggaagtata
    48601 aaaaatctat ttgcgccaaa agatttaaaa gaagattatc taagtgaact aggatatggg
    48661 gctcttatgg gacttcttta caattatgaa gtattaaacc caattgtaac agcttctaat
    48721 gatggattta atagattagt tcctggattt gaagctcctg tatgcatagt tacatcttta
    48781 ggtcatagtt atgagattcc atcaagaaat aggtcagtgc ttgttggatt aataagagat
    48841 atgaaaaatc caaagactgt aagatttgag ttaaggtcac caagccctct atctaacacg
    48901 tatttagtaa tagcaggatg ttatcaaaca atgttggatg gtataaaagc agcagctaag
    48961 agtggtctta gtacaaaaga acttgaaaaa gagttatcta aaaatgtagg tgaagaaagt
    49021 ttctatttag aaaaagatag agcatataga gatgaaaatg atgtatttga acattatagt
    49081 ttggaagaaa gaaatgcaag atttggaata ccaccggcta cagtttatga aaatatgaaa
    49141 aacttagaaa tatatgcttc aaaattaaaa tctttaaaac aaggtgatgt atttactgat
    49201 agtataatag aatcatttaa gattggagct atagataagt ggcaaaagaa attaaaaact
    49261 agaataatag aggctgggat tcaaaaaata agaagtattg tcaagataca cacaaaagaa
    49321 aatatggatg cgcttgatga ggtagtttgg aactcaatat cggatttaaa gttcaatatt
    49381 atgaaggata ctttaactag agaatcacta ttcactagag tgagagaagc tatagaaaat
    49441 aaggattacc agactgcttc agatttacaa atagaattaa agagaagtat ggaagaaata
    49501 caacaactgt atatgcagta caagaaaaat atatactaat ataacaattt gattttgata
    49561 tgataaaggc aatcaagtat tattaaacac tatgagtaaa ttctcaagtg taaaagcata
    49621 cttgattgcc tttaatttta tgtttgaaat tttttaatag tacaatttaa ctgtaatgat
    49681 tatctattaa ttctgatata taatcagcaa ttttctctgg atgaatgact gttttaaatt
    49741 cttttaaatt ttttttcata aagtttatta tagaatcaaa ttcatttgat actaatttat
    49801 aaaatatgtt tttaaggtct aggtcatcac tataaatcat gccaagaccc ttatctatta
    49861 taaatttagc gttttcaatt tcttgtccaa cttttggcat ttttacgagt actggagttt
    49921 gtgattgaat agcttcaaat atagttgctc ctccaggctt agttagcatt aggtcacatt
    49981 ctcttattag attatacatg tcgtttacaa atccaagtac tttaatattt tttagaggtt
    50041 ttttatgagt tagattgtca tataattttt tgtttttacc agtaactatt gtaatttcta
    50101 tagaattact atgttcttca ataaattcat ctatccaatg cataaaatcc tcatctatat
    50161 caaatagacc tcttcctcca cctagaagta atagtctata tttatcacaa catagttctt
    50221 tactttcaat ttgaaatctc ttatcaacag gaactccagt aacctttatg gagtctggat
    50281 ttattccttt ctgaaaaaat ctatttttta tttcaggaga aggaacaaaa tacaaatctg
    50341 tattttcaaa aacccattcc atactatcta caacatctgt tataactgta agtgtaggta
    50401 tatttatatc aggatttttt atcttaaagt tatttacaca agcagcagct agtggaaatg
    50461 tagagataat caaatctgga tttatatcag caatatactc agaaagttta ggtgtatata
    50521 atttatgaga taaatcatgt cttgaatcaa acgatttctt aaagtaataa tagtaattat
    50581 ataatccagg agtatatttt gtattgtttt cataaagttt taccataggc ttattcatca
    50641 tgggaatact tgcatttata aagttttgta taacaacatt atagttacta tatttttcaa
    50701 taatacattc tttgactgct tttgcagcac ttatatgtcc agcaccaaat tgagcagtta
    50761 ggattaatat tgttttatca tctttcattt tagccaattt atcaccactt tcataaaata
    50821 tatctgatta gagtattata catttataga aggatttaat caacaagaat atttaaaaat
    50881 aactattgtg cagaacatag tactgtgtta ttatgaggat ataagaagtt ttaacatagt
    50941 accttgtaaa acacaatact gtgtatttaa agaaaggatg gagtatatga acacacaatt
    51001 tagaaagggt gttttagaaa tttgtgtact tgctctcata tctaagaaag atatgtatgg
    51061 atatgagata gtacataaca tctctaaagt aatagatgta aatgaaggaa caatatatcc
    51121 tattctaaga agacttacaa aagatttgta tttcgaaaca tatatactag aatctaatga
    51181 aggtcctgct agaaaatact atagaataac ttcactagga aaagagaatt tatccaatct
    51241 gatggaagag tggagagaat ttgtaaaggc tgttgagatt ttaataagtg aagatgaggg
    51301 aggtaatgaa cttgaataaa actgagtttc ttgaaatttt aaaggattat ctaaaaaaag
    51361 atttttctga gagcgaagtt aatgatatat tgagagatta tgaagagtat ttcgtagatg
    51421 gtcttataga gggaaagagt gatatggaga taatagcatc acttggctca ccaaaatcta
    51481 tagcaaaaga acttatctta caaactaaag aaaaaaatat tgaagaggaa aaaataataa
    51541 atacagatgt tttgaatgat aagtttagta aatttaaatc agatatgaaa aaaggttact
    51601 ctatcttaaa agatgaagca aaagaaaagt atagtaaatc aaaagaaaat atagatggaa
    51661 aaataatgaa tacagacata ttaaatggta aatttagtag atttaaatca aatgtaaaaa
    51721 aggattattc tatcttgaaa gatgaagcta aggaaaagta caataaatca aaagaaaata
    51781 taaatgataa acttacacca agtatagaag aaggtgtagg aggattatcc agacaagtta
    51841 taaaggggtt attagtagtg ttatctttat ttctaattgt tccagcattt gcgtttgtat
    51901 gtgctattgt atctgctact attgcattag tatgctcatt aattgctttt gttatattaa
    51961 ttccatttgt gattaaattt atagcaatgg ttccagatgt tatgatgttt tgtattttcg
    52021 caaccatagc atttgtaggg cttgagatac ttgcatggca aattttatta tttgccataa
    52081 aactaggtaa acaattacta aataattata tacattggat aaagagaaaa aatatttata
    52141 taaaggcaaa tgaaaagatg gaaaaaagaa aaaaagctac tttaaatgat gaagatttga
    52201 ataaagacat taatgaaaat tcatataata atgattacta caatagagaa gaagaaagca
    52261 taaaagaaac tgatgaatat aatgatgata gtataaattt tgaggcgata tataaggacc
    52321 ttgaagatat agaaaataag aaaggagaag ataaacatga ataaaaaact tgctatattt
    52381 gctgcagttt tattggtaat aggtataata gggacaacat ggtcagggat tttagttatg
    52441 ccaagcctaa taaactttgg tttagaaaag gaagctgaat taaacaaaga aaacaaactt
    52501 tatcaagaaa aagtaaatat tgacaagtta gatatagctg ttgacaatat aaatgttatg
    52561 ataagaaaaa gttcaaatga agatgtgcgt gtgacaacaa gagggaataa tgaattttac
    52621 aaatacagtg taaccctaca agataagact ttagttgtaa aaggcgaaag aaaatctgaa
    52681 aataaaatta aaaagattag aagtttcgac cacttattaa atacatctat aaatagtatg
    52741 ttttcacgtg attatagaga aattagaata tatgtaccaa ataatgtaga tataaatgca
    52801 tcaagtataa gttcgtactt atttatatct gatgatgtag attcaaataa tataacatat
    52861 aaaacttctt ctggaggttt tagcagagct ataacagaaa ataaagtaaa tagattagaa
    52921 aacttaaact taatatctaa tagcaatctt catctatcaa caaagtcaat tttaggcgtt
    52981 aaaaatgtaa acatagaatc agagtcattg gatatatctt cagagaatgg agatgtattt
    53041 atcaataata tagaagagta tatacctgaa aatgtaaata taaaagagaa aataggtaga
    53101 aattcaaatt atgaaagtga attttacttg tactctgata tgccaattgc taagttcctg
    53161 gacatagaag ttccaaattc taaggtaaga cttgatatac cagtaaataa gtataaattt
    53221 aattgtgata taaagtcaaa agaagcaatt gaagaattta ataatgatga agaatatgac
    53281 aatgattcat atgattatga acataatgaa gaacatagca acaagtatag aaatacgagg
    53341 gaaataaaag ggcttttgaa taaaaatctg tcgaatttag agaaagaata tactataaaa
    53401 ataaattcaa atagcttaga attgtaaata atttactata ataatttata aattgattta
    53461 aaagtataaa aatataatct atactatggt ataataagta tcgaaagaga attaggagag
    53521 ggatacttat gaataaaata gcagtaagtt ttttaataat tgctactact ttattgagta
    53581 cggcatgtat ggattatagc atcagtgcag ttgagctagt tgattctaaa gaatcagcag
    53641 ttgtaaagaa ggatgaagat gcaaaagaag aaacaactag taaaatgatt aattctaaaa
    53701 aaactactaa aatacctata gagataattt caaaggatga gaaaatagta aagtacttac
    53761 agattgatga agaaagttca cttaaggata aactgcgatt aatcttagat acattatcaa
    53821 atgagtattt taatggttta gacatggaag tagaagttaa ggaaaaagat aatcttgtta
    53881 aaataaactt gatagaacca gataaaaaaa gtagagtttc ttggaaagat gattatttga
    53941 atgaacaaaa tataatatat actataaata atattattaa aaatgtcatc caagaagaag
    54001 ataatagcat ttggattgaa gaagtagaga tatactacaa tggaaaatta atagaattaa
    54061 gataaaaaaa gatgtgtttt taacacatct ttttttgttt tttaattctt ataaaatcct
    54121 tatatttatg atttagaatg attcttgtaa ataagtttga caaaagaaag gatgaaaatt
    54181 atgagtaatt atattttgca ggtaaaagga gtttctaaaa aatttaagga gcagatggca
    54241 gttgataaca tttcactagc aattaaatct aattctatat atggattatt aggaccaaat
    54301 ggagctggga aatctacttt attaaaaatg ataactggga ttttaaatcc aacttcagga
    54361 aaaataatgt ttgagggaca tagatggact agaaaggatt tatcaaatat tggttctctt
    54421 attgagtctc ctgctatata tgagaattta acagcacgag aaaatttaaa agtccatact
    54481 actttacttg gtcttcctga ctctcgcatt gaagaagttt tagagactgt agatttaaga
    54541 gataccttta aaaagcgttc aggtcaattc tctctaggca tgaagcaacg ccttggtatt
    54601 gctattgcat tattaaatca cccaaaactt ttaatcttag atgagcctac aaatggtctt
    54661 gaccctattg gtattgaaga acttagagaa ttgattcgtt cttttccaaa acaaggaatt
    54721 acagttattt tatcaagcca tatcttgtct gaagttgaac aagttgtaga tgaaatagga
    54781 ataatttcta atggagtaat gggttatcaa ggagaagtat caaaagaaca aaacttagaa
    54841 gaacttttta tgaaagttgt agctgaaaat agaaagagag ggcagtaata tggaaagatt
    54901 tattagagtg gaatttcaaa agatgaaagg aacttttgga atgaagttga tatggatagt
    54961 tccagtgttt tgtatacttt tgtgtggact aggtggaggg caaaatgctg ctttcaactg
    55021 gtggtatacg acatttcttc caggagcatt aacattaata tcttctttaa tagtattaaa
    55081 agatgaaaaa agtaaatatc gtggtatttt accattgcca attgaaatga aagacgtttg
    55141 gactggaaaa atgatttact gtattatttg ttgttttata gcatcaatta tttctgcaat
    55201 aggtgtagtt tttgttggga taatctataa agaaactatt tcaataggtc aaaatatcat
    55261 tgcaagtata ttaattattt tactatttat gtggcagatt cctctttgta tgtttttagc
    55321 ttcaaaattt ggtatgtttg ttacagttct aacaaatatg ttctttacta ttgttggagt
    55381 tgctgttttc tcaactacag aaatgtggta tatgtttcca tattcgattc cttcaagatt
    55441 aatggctgtt gtattgcata ttctgccaaa tggtcttcct gtaccagagg gaagtgaatt
    55501 tttaaataat gctgttattt tgccaggagt attaatatct attgttttat ttgtattatt
    55561 tgctttagct acaagggttt ggttcaataa tagagaggtg aagtaatatg agacagttaa
    55621 taagaatatt ttgttctgat ttaataaaat taaagagaaa ttttataata ctaatgcaca
    55681 tttgcattgc tttaatgggg atgggattgt ttttatggta ttataaggtt tcaggagctg
    55741 ataatatact aaagatagta gcatatttac aagttatagc aatagctttt cctttattgt
    55801 caagtgttgt gtgttcaatg tttgttgaac aagaatatta tgcagggaat tataaacata
    55861 tgttaacaac atctaatcca aaatatctta ctcttataag taaatatata atcttagtat
    55921 gtcttggttt tgtagcaaca ttagtgtctg tattaggttt taaatttggt atatctaagg
    55981 cttactttac atcaagcttt tatatgattt caattctaat tttaattggg tgtaatttat
    56041 ttgaatacat attacattta ttcttaagtt taaggttcgg aaaaggaaca tcaattggag
    56101 taggtatagt tgaaatgtta ctttcagcat tattattaac tggattgggt tctggtattt
    56161 ggcagtattt tccttgtgca tggggtgtta gatttataac tatttggtcg tctttttcaa
    56221 gttctaaaac ggttgaatat ataaaggttg aatcaataaa agcatatcaa tcaacaggtt
    56281 taatttgtgg ttttgtaaca attttagcat ttgtaatttt atgtatttgg ttttctaaat
    56341 gggaaggtaa aaaatcagaa gaatagagta aaaattgact gtttatttat attattatgt
    56401 taaaatataa cttagcaata aaaagatata aaataatcaa ataaaaaact ggttgggtat
    56461 taattatgaa ttaattaaac tattggagga cagggtacaa atgcttggag gtaaaaaatc
    56521 taacaacaaa aaagttgaaa agttaagaac tatttttata aaatatttat ctttattctt
    56581 tattatgaca atttcaattg tactcctttt aatgttatca ttttctgtat tattatcatc
    56641 aggtgtaatt ttaccagcta attatgcaga aaaacaattt aataaatata aagaacagat
    56701 tatttcaagt gaaaaagtaa ctgaagatat aattccaagt atatatgagt atggggttta
    56761 tactttggat gggaatttaa tttcagggac ctttaataaa aaagaatcaa aagaagtatg
    56821 gaatttaatg agagatattg aagaaaggca tgcatattca gaaagttata taaagttttt
    56881 taagaaagat gaagttttta taataaaata caaaatagta tcagagtata gttctccaat
    56941 tttaagagca tatttaccaa aaccagagac attgggtatg attattttta gtataatatt
    57001 ttttattgaa attgttatat tatcaaaagt atttggcaag aaatttaata ttgaaatgga
    57061 gcttttaaaa aatactacag aaaaaataga acaacaggat ttagattttg ttgtagaatc
    57121 tagtaaaatt tatgaaatta ataatgtcct tttttctatg gataaaatga agttggcgtt
    57181 aaaagattct ttagaaaaac aatggatgct agaagaaaat agaaaggaac agatatctgc
    57241 actggcacat gatataaaaa caccactaac aattatacat ggaaatactg acttattaat
    57301 tgaaataaat gaaaatcctg agttattaga atacatggaa tatatctcaa agggtgtcac
    57361 tcaaatagaa aaatatatta atactttaat agatatatca aaaacagaga atggctatat
    57421 attaaataaa gaagcaatca gtatgagtga gtttataaaa gatgttttag tgcaaataga
    57481 agcattagct agtactaaaa acttagatgt ggagttttat aaacaagata atttgcctaa
    57541 aaatataact atagatagag aactgttatt cagagctatt atgaatataa tttcaaatgc
    57601 tatagattat tcaccaagcc agagtaaact atacataagt gtatcagtac ataataaata
    57661 cttaaaattt gtagttacag attgtggaag tggtttttct aaagcagatt tgtcaaaagc
    57721 tacagaacag ttttatacag gagatttgag tagaaattct aaatctcatt atggaatggg
    57781 actctatatt gtaaataata ttgtacaaaa acataatggg actttatgta ttgaaaattc
    57841 tgtgaaaact ggtggtgcta tggtaacaat tgaaatacca atagtttagt aaataatatc
    57901 cattttgtaa atacctaaat tttatgattt ataggtattt ataaaatgga tagttttttt
    57961 gattttatat attggttaaa tctgataaaa agttttcaaa cataactcca tcatttctat
    58021 cagtatcaaa ttgagatgtg taatttatag ttttatatat aaaatctgtt gcagtattaa
    58081 ccgctactcc caaatcatgt ttatttacta acataccaca aagtatagat gtgaatatat
    58141 ctccagttcc actgtaagaa caattattat atttgactga tgtaaagaat acatggtcat
    58201 tatctctatt gtaagccaaa tttaatatat tatcatcttc taatatacca gtaataacga
    58261 ctttgctagg tcccaaatca gatacagatt ttgcaatata tataagctca tctctattat
    58321 aatcgctttt ggtataatca tttccagtta agaaacaagc ttctgttaaa ttaggagtag
    58381 ttaaatctga atgtttaact aattctttaa tttcctgtct catttcttct gtgaatattg
    58441 gatacataac tccattatca cccatcacag ggtcaactac gataaaagca ttgggataat
    58501 cgtttataaa attagccact atctcaattt gatgctttga acccaaaaaa ccactatata
    58561 tactatcaaa attgactttt aaatttttcc aaacatttga atattttacc atttcatcag
    58621 taaagtctaa gaaagtaaat tcaggataac cagtttgact tgaaagtatg gccgttggaa
    58681 atggacaaca ttgaaccttt aatgctgaaa gtataggtat agcaaccgat aatgagcatt
    58741 ttcctattcc agataagtca ttaattgctg cgactttttt ttgcataaaa aaccctccat
    58801 tagtatgtat taattataat gataccaaaa tatttatata catatatatt actataaaaa
    58861 aaagaaaaaa gtagattata aaataaaaaa ttgtaaaaaa aacagtgtat tgatacaatt
    58921 aatttttaat attggacata ataaaataga gaattattaa atatgaaaat tactatatgt
    58981 gacagaatat tctttgtaat ttgatttgta aggtgtacta tttgggaggt gtagctttga
    59041 aaatactgaa aaataagaat aagtacatca aaggtataat ggcatttgta tttttgtctt
    59101 tagctactac agcaggtgta tttttaatca atgatttaag tatgaaaaat atggaagaaa
    59161 aagtcatgga atctgcaaat gttgaaggtg atgatgtaaa agaccaatat aaactattgc
    59221 ttgaaaactt atttgactac agaaataagg caatattaga gaaaaatgaa aatattttaa
    59281 aaggtcttta tgaaacggat aaaaaatttg gtctgtgggc ttatgaaaat gaagtaaaaa
    59341 agatgaaata tttagaaaac tggtctagta aacaaggtgt aaaatttaaa gacataaaga
    59401 caagggttaa gattaaaaaa ataaaggaaa aagaaaaaga cctctatggt ataatctgtt
    59461 cagtatccac tgaatataag tattcatatg aaaatcaaaa ggacaaagaa aatgccttta
    59521 gaataggtac atatcattat ctaaatgtaa aaattataga taatcaatat gtcataacta
    59581 aagagtggta tacagaccct tttgcagact ctttaaattt agaaaatata aaatctgatg
    59641 atataagaaa ttatattggt caacaagatg gtgtagagtt acagcttaca gatgaacaaa
    59701 aaaaagctat agattatgca cataaatact gtggagccgc agctgatgaa gaacatggta
    59761 tgaaatttaa tccaaactat agggattata atccagaagg tggagattgt gcaaactttg
    59821 catcacagat aatgtttgaa agtggaaggt tcaaaaagaa ctcaatttgg aattatagcg
    59881 agagagcagg tacaaaagca tgggtaaatg cacaagcttt taaaaattat gcactgtata
    59941 gtggaagagg ttcattaatt gctaaaggtt cctatgaaga agtatacaaa gaagcttata
    60001 atttacgtcc aggggatttt gttggttatg agaagaaagg cagaataaca catgtttcga
    60061 cagtgacagg attagactca agaggatatc ctttggtaac ttgccataat actgatagaa
    60121 tgttggtgcc atgggattta ggctggagtg ataagtccat aagattccat ataataaaaa
    60181 taaattatta aaaaattata aagaaaaata aagtgtaaaa gataataatc atttaaaatt
    60241 ataaagtaaa aaaattgatt attaatgtat aaaaataata ataattgaca aacatagcta
    60301 tatatgatag agtagtaata aggttacaga aaagagtagc taaatatttg tgttttttta
    60361 ggaggattta ttaatgaaaa ctggtgtagt taaatggttt aacaacgaaa aaggatttgg
    60421 attcatatct gtagaaggtg aaggagatgt tttcgtacat ttctcagcta taactggaga
    60481 tggatacaaa acattagaag aaggacaaag cgttgagttc gaagtagtag atggagctaa
    60541 aggtcctcaa gctgctaacg tagttagatt ataattaaaa attcatatat attagtgttc
    60601 tagtaatatg agagataagc cgctaatcat ttagcggttt tttcagtttt tgtaaataaa
    60661 attaatagca aaataaatta aaattattaa aataaaatca ttaataatga gataaatatg
    60721 ttaaaattaa tagtgtagag taaaattatt atggctaagt ttaagtcaat taatttttag
    60781 taaattttct aaaaagagaa taagtgatac ttatagacca tataaaaata ttaataaagc
    60841 ataataagat taaaatgagc aaaggaaaaa cgcttgttac agcgtatagt attaagaata
    60901 cttagaaaat aagaaaggag aaagttactg caaaaaagta acattataaa tattgagtaa
    60961 tatttataag ttttcagtaa cggtgggtag tgtaatgaac atattattct ttctaacacc
    61021 aaaaagtgaa gtagcatata tatatgaaga ctacactata aggcaagccc tagaaaaaat
    61081 ggaatatcac aaatactctg caattccaat aataagtaag gatggtaaat atgttggaac
    61141 tataacagaa ggtgattttt tatggacatt aaaaaatgat ttaaatctgg acttaaaggg
    61201 attggaagat gttccagtga cagatataaa tagaaaaatg gataattctc ctgtttccat
    61261 caacgcagat attgaagatt tagttataaa atctttaaat caaaatttca ttcctgttat
    61321 agatgaccaa gacacattta ttgggataat aaaaagaaga gatgtaatag gttactgtta
    61381 tgagataata cgtggatata aaaatttagc taatgataat taaaaatctt atttaaactt
    61441 ttaagctgag ttctttacaa taaaaaaatg ataatatgaa actgaatatt taaactttaa
    61501 tataaaaagc tgtcttttct aataaatatt gtgaaaagac agctttttta tatatgacct
    61561 tatgattaat cgttgtattt tacaaggttt ccgtacttag cattaagagc atttatctta
    61621 tttccataaa cttcattttg tttttgatat aataaacttt tttcaacttc agccttaact
    61681 tcatcaaatg tagactctgt actttcttga aggtcttcta attttattat atggtatcca
    61741 aattgagttt taactggttc acttacttca cctttagcca tagagaacac agcttcttca
    61801 aattcaggaa ccatttgtcc tctaccgaat gttcctaaat caccacccat atctttagat
    61861 gggcaagaag aatgtttaag agctgcatct tcaaaagata tttcttctga ttttatttga
    61921 gcaagtattt ctttagcttt ttcatcacta tctactaata tatgtttagc agttgcactt
    61981 tctggtttag agaaagagct cttattagct tcaaagaatt ttactttttc atcttctgtt
    62041 acattaacac tagataaaac tttatttata gcaaattgct ttaatacatt ttcttctatc
    62101 tttttcattt ctaatttaaa tatttcttct tcatctaatt tttcttcttt agcatctaag
    62161 aagaataatt cttgattcac taaatcattt aataagtgtt tttttccttc ttcagtttta
    62221 aattgcatag cttgataagg gtctaatgat tttaatgcat tttcaatatc aatattagtt
    62281 atctcttttt ctccaactgt tgctaaaact tttttttcca taatagttaa ctccttcata
    62341 gtgtatttca ttattaatat aagactacca tcttaaataa tatcagaaaa taatgtagat
    62401 gtctaatatt taaagccata ttaagtcaaa tagaattaaa tttagtagaa caaagttatt
    62461 acaattaata aaagtgagct cataataccc actacacctt cgtcatcttt aaatttaaga
    62521 gtttttacta ttgaataata aaggtatatt ccagtaaaaa taatctttaa atacaagaaa
    62581 aataaactct ttgggtatat taaaaagcta aaaagtgtaa atataaaagc aagtagagta
    62641 cttatcctgt aaaagaaatc tatttgtgta atgtctttat attttatcat aaacaccgaa
    62701 tataaaatga tgaaaacaat tgcgacgatt gcatatatgg taaataacat attttcaaga
    62761 gtaccatttg aaattactat ccacttatac cacataattg gccaaaataa tagtgctaag
    62821 aacttaaaat aattatcaaa caacttttct ttatacattc atcaaacaac ctttcttaac
    62881 aaaagcatat atttgttttt agaattttaa ataatatgat atcattatta tatattaata
    62941 ttgaatttat agaaaccaaa atttgttaaa ataaatatat agattttact gttaagccag
    63001 ttaaaattac tactattttt attatgaaat tggatcaaat atgtagaaat acggcaaatt
    63061 agttaatatt aaatatttat tatttccaag ttgtaaagac tgttttttta atgatagaaa
    63121 ttctaatctt ttttgaaaga aagtaatatc cacattaagt atgtctgcca tttcataaac
    63181 gcaagtgatg ccagagttaa ttatgtttat tatatcttct tcagtaatta agaactcaca
    63241 agcccatttt aaggctttat tttcgcactt atctataata atttttgtat aataatcgtt
    63301 ataagaggat acatagtatc caaggctagt gaaatgatgt ccaagttctt cagctaagat
    63361 ggatgtcaat ttttttgagt tttgttttaa attactgagt aatgatataa ttttaatacc
    63421 atgtttgttt atatatagtc cttctaaatc acctgcaata taagtggtat aatgaattat
    63481 tatctcttct tgagaagcta attcaaaaag cttatccaaa ttattcataa aaatccccct
    63541 aaaatagaat gtatgtttgc ctttgaatta tattaaaaga gcagaaaaat agactgctca
    63601 tcatatggtt tatttttttt tatatttatt tagtaaaaat tctatataat cattaagttg
    63661 ttcttgtgct tcttcaggta actcttcatg tggatttttt ctatgtgcag ctactgtatc
    63721 aatattttcc ttaactaagg ttcttccaag aaggtaatca actgatacat taaatacatc
    63781 agccaattta tttaaaatgt gttcatcagg aaatctgttt tctgtttcat agtaccctaa
    63841 gactctttgg gaaacgccta ctttttctcc aagttctctt tgagtcaatc caaattcctt
    63901 tctaagttct cttaatcttt tggcaaacat tataacacca ccttatgtat agattataac
    63961 aaattgttct aaaaaataaa actaataaaa tataaaagaa tatttttttc taaaatctat
    64021 tgataaagaa caaataattc tatataatct aagtgaggaa gaacaaaata ttcttaatag
    64081 taatggaggt ataaaacaat gtttaaaaat aacttgaaat attatagaaa atgcaaaggt
    64141 atgacacaaa ttcaacttgc cagaaaggct ggaattacaa atgattatat atctcaaata
    64201 gaaagaggca taaaaaatcc tggacttctt atggctaaga agatttctag tattttagaa
    64261 caaaatatag aagaagtttt ttttatacag ttatagaaca atatgttctt gaaggttgtg
    64321 agattagtaa aaaactgtgc actaaagaga ttattgtaaa tttgaagcta ataataagta
    64381 tataaaaaag gggaagtact atggaaaaca aaaaagatat attatttaaa gaaacagata
    64441 aaagattaca taattataag tatttggata taaagataaa gaatattaac ttggacataa
    64501 aaagatgtga gaatgaatac tctggatgtg gagcaatggt atatacagaa aagactagta
    64561 acacatataa cataagctct tctgtggaaa atgaggtgtt aaaaagagag gaaagattaa
    64621 gaaaattaaa aatggaaaaa gaagatatag aaatagaaaa agagaagata gaaaatgctc
    64681 taacgtgtct aaatgatata gaaatggaat tttttaatct tttttataat agtaagacaa
    64741 aaaacaatat gacatatatt tctatgaaac tacacttaga tagaacatct tgctacaatt
    64801 taaagaaaaa gatgatattt aaattgagtg agatattata aaaaatagga caattttaca
    64861 acactttata tacaccatta caacaatagg caataaaata tgtgagataa tgttattgtg
    64921 aaagaaatcc atattgaagg aggtgataga ttgaaaagaa taatattacc taaaaatata
    64981 gaagatactt gacaggaata aatgagatat atatttaaaa atgacttata tcatttatag
    65041 taagattatc agattaagca agaatattta gtgatagtgt ggtgattatt tgcttaaata
    65101 caaggaaata ttagaaacaa ttattgagat tctcaaaaaa aactttactg aaagtatttt
    65161 tattgatgat gaaagtgtgc aaggctctga agggtcttgt ttttttgtaa gtatactatc
    65221 agttatttgt acacctgtaa tgttaaatac gaataacaaa gatattgtta tctctataaa
    65281 atacttacca aaaccacagt caaagagtat tagaatgtat gaagtttcag atgaattaaa
    65341 taagttattc aacagaaata taaaggtaac agacagaaaa ttaaatataa caaagctaga
    65401 acaaagtatt aaaaaagaag agtcaattta tgtattgaac tttacattta cactaaacta
    65461 tctggatagt gtatatgaag aagatgtagt atatgaaaat atggaagaaa tcaatttaaa
    65521 tttaggagag tgatagtatg gctataggat taccaagtat caacatatca tttaaggagc
    65581 tagctacaac tgttaaagaa cgttcagcta gaggaataat tgcaatggta cttaaagatg
    65641 ctaaggcact aggtcttaat gaaatacatg aaaaagagga tataccagtt gatttatctg
    65701 ctgaaaataa agaatatata aatttagctt tgatgggaaa tgttaacact ccaaataagt
    65761 tattagttta tgtaatagaa ggagaagcag atattcaaac tgcattagat tttttagaga
    65821 ctaaggaatt taactatcta tgtatgccaa aagcagtaga agctgataag actgctataa
    65881 aaaattggat aattaaactt agagatatag ataaggttaa ggttaaagct gtattaggaa
    65941 aagttgtagg aaatcatgaa gggataatta attttactac agaagatgtg ttagttggag
    66001 aaaagaaata cagtgttgat gagtttacaa gtagggtggc tggacttata gcaggtacac
    66061 ctttaagtca atcagtaact tatactaaac ttagtgatgt agtcgatata cctaagatga
    66121 cgaaagttga tgcagaatca aaggttaata aaggagagct tatacttatt aaagaagcag
    66181 gagctataag aattgctaga ggagtaaatt ctttaactga attaacagca gaaaaaggag
    66241 aaatgttcca gaaaataaaa atagttgaca ctttagatat tatacatagt gacataagaa
    66301 aggtgataat agatgactat ataggaaagg ttactaacag ttatgacaac aaatgtttat
    66361 tgatagtagc tataaaaagt tatttagaag aattagaaaa atcagcactt atagaatctg
    66421 attctactgt tgaaatagat tttgaagcac aaaaatcgta tttaaaatca aaaggagtag
    66481 atttatctta tatgacatta caagaaataa aagaagctaa cacaggttct aaagtatttt
    66541 taaaagcaaa aataaaagta cttgatgcta tggaagatat agatttatca atagaaatat
    66601 aggaggatta ttaatatggc aaatatggaa gctagaaatg taatgagtgg tacttgggga
    66661 gaactttggc ttgatggaaa caaagtagca gaagtaaaga aatttcaagc aaagatggaa
    66721 tttacaaaag aagatattat aatagcaggt caaatgggta ctgatacaaa gtatatagga
    66781 tataaaggaa aaggctcaat aactctatac cacgttagtt caagaatgca caagttaatt
    66841 ggagaaaaga taaagagagg ttctgaacct aggtttgttg ctatatctaa attaaatgac
    66901 ccagattctt atggagcaga aagaatagca gtaaagaata tagcatttga tgatttaact
    66961 ttagctgatt gggaggttgg cgtaaaagga gagatagaag cacctttcac atttactgag
    67021 tatgattttc ttgatataat ttagttttat atttagtttt atatttggtt ttatactgat
    67081 atttagtaaa tatatactta ataaattcag atagttaata agtaaaaaag ttagttgatt
    67141 gaatttgatt gataaaggag caaataataa tgagtgaaaa tggattatca aaaaatataa
    67201 acatagtaga tttactttta aattcagata cagaaaactt agaaagaccg agtactatag
    67261 ttgaacttaa gagattatca actatatttg ggcaggaatt taaagtaatg tgtagagctt
    67321 taacaataag taaagatgaa gaaatacaaa atacttgtct taaaattgat gaaaatatga
    67381 aaacggatat agacttaccg gagatgcaga tgcttacaat tatagaaggt gtttgtgatt
    67441 tggatggaaa gcttttattt aaaaataagg agctaatgga taaatttaag gctccaacac
    67501 caaaagaatt agcaagaaaa ttattattac caggtgaaat taccaactta tatagaatac
    67561 ttcaagatgt tatgggttat ggtaaaaatg cagtgataga agaggtaaaa aactaatagg
    67621 gacggatacc aggactacaa taatgtacta ttattggaag aaaaaaggta taagaccgtc
    67681 ccttttttat gcaatggata aaggcgaatt aaagcttatt gaagcttttt tcgccttaga
    67741 aattgaggaa gaagttgaaa aaatgaaaca tggatatgga gtgtgtcctt tgacaggagg
    67801 tggtatgtaa tgggaaatgt gagagaagaa ggtataaata tgtaccttac agataattac
    67861 acaccaaaaa tgaatcaaat tatatcagta actgataatt ttaggagagc aactgtggct
    67921 gtttcacttt ccactaatgt aatggctagt agcataaaaa attctattgg aagtgcaagt
    67981 aatagagtaa acagtttaaa ttcctcgtta agaaaagttc aaactactgc tagtagtgta
    68041 agttcaacta tgacaaaatt aagttctagc ataaatgctg tttcaggagt tattggaagt
    68101 ttaaatggaa gtattatgat actagcaata actatagcta tgattattga ttattttaat
    68161 aagttgattc aaaagaaaaa tgagtttaat tcaaatatta tgattatatt aatatttaaa
    68221 gctaaaagtg atgaagtaga aaaaactaaa aataaattac ttggaaattt aaaaaagatt
    68281 ggtggcaagg tttggaatat cgtaataaaa gcaaaagata tgactaagag agttataagt
    68341 agtatcttgg gaaaattaaa acaagtagag aaacgtcctt atcaaggaag tattaatctt
    68401 aaagatatgg tgagtagtgc tatgggtaga attttgccta agttaatgtt gtttaaaaat
    68461 actttttgga gtggtgtaat agctataaaa gatatggcaa gtggcattat aagtaaagta
    68521 tttcccaaat tgagattatt tgcaggtaag gtatggagtg gtgcaatagc tgtaaaggat
    68581 atggcaagtg gaatacttgg ttcgataaaa gggaagatat ctgatttgac aaatggtgct
    68641 actataggtg tcgctgtgaa aaagggtgtt gatttacttg gtcaggaaca aaatcagaaa
    68701 gttgttctag aaagtgtaat gaaaagaaat actggaaaag ttaatcaaat agatgttgat
    68761 gattattatg gcagtttagt aagaatggca aatgatacgc cttttgaccc tgaagatgtt
    68821 gttgcaatgg gaactaaagc taaaatgatt agtaatatta ctggtggcaa aaaagaaaaa
    68881 gatataactc aagctatggt agatgttaga gctttaaata tgaatacaag tagtgaacaa
    68941 gatgtatcag cagctttctt aagtgcagca aaaggaaaca tggaatctct taatactctg
    69001 gtaggagaaa attataaaac ttttgatgaa gcattggaag gcataagtgt aaagcagatg
    69061 gggttagcta aagaaatgag taatacaata ccaggtataa tatcaggagc tcaaacaagc
    69121 attaacaatg gcttgaagag tattgttaaa ccttttgatg atattttagg tcaaggacta
    69181 aagaaaataa aaacttttat agaaagtgga ttaggcaatt tagctggctt atctgaaaaa
    69241 atggctggta aaataggcaa tgtaatgaat ggtaagataa ttattggcaa caaatatgac
    69301 cagatgcaat ctagaagtgt aaaaaatgga aaagagtttt ctgattctac tcaatatcga
    69361 atttctaatg aggctgaaaa gcgtaaaatg atggttgaaa ataagcaaga acgttttgaa
    69421 aatcatgcag caacaatgat agggaatgca ccaaaagcaa ttgttaacgc aggaagtaca
    69481 ctattacaaa atatcgattt tacagcatta atagattcat tacttccagt agtaaactta
    69541 gtaaataatt tactagatag tataaacaat aaatcaccaa ttgcacaagg attaataagt
    69601 atatttggta caatagtaac tacagcattc caactaatcg gacctgtagt tgaagctgtt
    69661 agtcctatta tcacaagaat ttttactttt ttaggtgaat atgcacctca aataaacaat
    69721 tttatagaga cactgggtgt tatttggaaa actgtatggg agaccttagg acctctgttg
    69781 gaaactggat ggaaaattat agagccaata ttgggagctt tttttaacat attagataaa
    69841 gtatgtaaaa tagttaaaga tatatgcaag tggtggcaaa ctatgattaa taagataaaa
    69901 aatggaagca tcacaggaac agttttaaat ctagtggaaa agagtaaaaa aaattacaaa
    69961 gataatccat atgctggaac aaaggctggt gattctggta aagcttattc aggtaagaaa
    70021 ggtaataatg catttggatt gaactatgtt ccttataatg actatcaaac cagactccat
    70081 gaaggtgaaa tggttttaac taaacaagaa gcaaatcaat atagaagcag aaaaaatggt
    70141 ggaaatataa acatagctaa gttagctgat acaatagtga ttagagaaga agctgatata
    70201 gaaaagataa catcaaaatt agttgcaagt atccaattgg cacagttagg gggtgtctta
    70261 taatggaaat gtggcttaga caagctgaag atagatttag atttccagta tttccatctt
    70321 cctttagtat taatggaaaa gctgctgtaa actcttctag tatactcaaa ataggtgaaa
    70381 tagcaacttt tggtggtgta gctcttaaaa gcatttcaat atcaagtttt tttccaaata
    70441 aagactatac tttctgtgac tatacaggtt ttccatcacc atatgattgt gtaaataaga
    70501 tagaaaaatg gatgaaggaa ggttttatat taagatttac aattacggaa acaaatataa
    70561 atatggaagt cataattgaa gggtttagtt atgaagaaag agatgggact cgagatgtat
    70621 attttacatt agatttaaaa gagtataaaa gaataaagat accaaaagta actccaaaac
    70681 aataactatt atagataata agttataaat aactgcttat agaattaaat gaaaaggcag
    70741 gtgatttttt attattaaga tttgggtaca cataaaaaac ggaagtatat atgacataac
    70801 tgacatagta gacaaggtat catggtcagg tgattataaa tctccatcaa ggacactaga
    70861 gttttcaata atacaatcat catttgatgt aaatttccaa caaatagata taccaatagc
    70921 tagtacagtc tgtttctatg tagatgagaa agaactcttt agaggaatga taattaatag
    70981 gtctaaagat tcaagcagta atgaaattag ttttgtatct aaagatatgg gatttttact
    71041 tacacaaagt gaagtgtcat acaattttaa agataagtta gttgaagaca tagcaaagca
    71101 agtatttgct gaaaataggc tttcagttgg aacaatagca aagaccaatg tcaagtatac
    71161 aaagatgttt ataggagtaa atggttatga cacaataatg agtgcatata cagaagcaag
    71221 taaaaagaca aagaaaaagt atatgataga ggccaattta gataagttta atgttattga
    71281 aaaaggaact gttacattaa atgttatgtt tgaagaggga tttaatatta taaataccac
    71341 cttttcggag agcatggaaa atgtaaaaaa taaagtaata gtggtagacc agtatggaag
    71401 caagattagc gaaaaaatag ataatgaaat ttttaaggaa gtaaatgtaa taatgcaaaa
    71461 agtaattcag caacaagaaa atcaagatgt agatattgat agcgagttta atgggataga
    71521 aaaaagctgt tctcttaaag gttatggaga tgtaagttgt ataactggta gaggagtaaa
    71581 agttaaagat tcttatacaa agcttgtagg actattttat atagatacag acaaacatac
    71641 ttggcaaaat ggagaatatc aaattgagct tgaacttaat tttcaaaatc ttatggatga
    71701 aaagtcagca ggacaggatg aacctaagga agaaagtaac ttagggggag aagattatgc
    71761 aggaggaaaa gagtttacag cagaatttac agcttactgt cctagaaaag aagaaggtgg
    71821 agatacagat tgtagaaaga aaaaacttga cccatctaaa aaaacttgcg ctgctcctat
    71881 ggttggtaaa tatgaacaaa cttattatac aaaagagttt ttaaataaac atcctttatt
    71941 aaactatgga gatgaaatac aggtaattac aggagtttct ggtcgtgatg gagtctataa
    72001 agtaaatgac gtaggacctg caataactat agaaaagaat ggaacatacc atatagatat
    72061 tttatttgga aatgttgaag aagctagtaa atttggaaga agaaaaggaa aaattattat
    72121 tggtggttat tctggtaatg tatctgataa agctaaaata gtaatatcag aagcaaaaaa
    72181 acatctaggt aaaccttata aatggggtgg aaatggacca agtagttttg actgttctgg
    72241 tttaatggtc tattgtttta aaaaagttaa tgttagtttg ccaagaacgt caaatcaaca
    72301 atctaaaaaa ggcaagaaag tagaacaaaa aaatcttcaa gcaggagatt tagtattttt
    72361 tcataatcca gtcagccatg ttggattata tataggtaat ggagaatttt tacatgctcc
    72421 acaaaaaggt gatgtagtta aaataagtaa gttaagtagt agaagagatt ttaatacagc
    72481 taggagagta ttataaaagg atggtgatat aatggctaat ccaataaatg aatttatagg
    72541 aataataaga gaagaaggaa agtatcataa tcaaccttct ttttttattg gaaaaattaa
    72601 aagtaaatta ccagatttaa aaatagagac aaataacatc atattagaaa aagaagatat
    72661 tttgatagat agttggatga ttgatagaca gctagaaaca tttgacacag aaacaaatca
    72721 agaacaccag catgaagtaa aaaatccttt tatagataat tttgaatctg gggatatggt
    72781 aataatgttt agaataggcg aaaaatttgc tgttgtaagt aagttggtga gcttataatg
    72841 agtacaatat ttccttttat aggtgtccca gaggattata tcttacctaa aacagaagaa
    72901 ttgccaatct ttcgtgaagt ggcatgggat tttgaaaaag atgaacctat tttagaaaaa
    72961 ggtgacttta aaataattga aaaaaaagaa gccttaaaag tttggatata caagtgtata
    73021 aagacaaata gatatgaaca tgagatatac tctttagaat atgggacaga gctttcagaa
    73081 ctaataggac aaaaatatac aaaaggtctt acagaaagtg aagctagtag attcataaaa
    73141 gaggcccttc taataaatcc atatatatta gaagtaaacg taaaaagtgc taactttaac
    73201 agagacgtat tgagtgcaaa tgtaaaagta tccactatct atggggaggt ggaaataaat
    73261 gtatagtgac cagacatatg aagtaataaa aaatagaact cttgaaaata ttaatcttga
    73321 tatttataaa ggagaaggtt cttttctaaa caacatggta tctggaaata atctagaact
    73381 ttcaaagata tatctagaac tttcaaagat acataaaatg gcttttatac aagacacata
    73441 taaccagttt ctcgataaaa gagtcaatga atttggtgta tatagaaagt taggtacaga
    73501 gtcaaatgga gaagttgaat ttattggaga gaaaggaact gtaataaata atggcacaat
    73561 aatatcatat agagatttac tatttgtagt aataaaagat gtaactattg gtagtgaaga
    73621 aggtgacaat agcccagttc aagctctgga agttggtaag aaatataatt tacctacaaa
    73681 ttgtgaattt aaactagttg ataatatatc tggagtaaca aagattacta acacaagaag
    73741 ttttgaaggt ggtacagata tagagacaga tgaagaacta aaagaaagat tttataaaat
    73801 ccaaagaaat caagctacaa gtggaaataa agctcactat gaagaatggg ctttggaagt
    73861 agatggagtc tataatgtta aggtttatcc aagatgggat ggtccgggaa cagttaaggt
    73921 cttgatattt gggaaaaata atcaagctgt tgatacagaa acaattgaaa ggtgtcagca
    73981 acatatagat gaagagaagc ctattggacc aactataaca gttgtgacac cattaccaat
    74041 agaaataaat ataagtgcag taatgaaatt agaagatgga tatacattag acaatgtaaa
    74101 agaatctttc ctagaaagta taaatacata ctttagagat attagaggag agataatcta
    74161 tacaaaagta atgggaatac ttataaatac tactggtgta cacgatttaa gtaacctact
    74221 tataaatgga agtacagata atataactat taatgaagat aaaataccta gtgtaacaac
    74281 tgttaatttt agtgaggtgg aaaatcaatg aagctaattg ataaactacc atcatttgat
    74341 agaaattaca ttgtagagga gatacaaggt gcatacgata cagaattaaa tattcttaaa
    74401 gaagatattg atgatacctt taaccaatta tttgttgaca ctgcaacatg gggattagat
    74461 atgtgggaag acatactctg cattgaaaaa aaagaacttg attttgacac aagacgtagc
    74521 aatataaaag ctaaaatgag aagcagaggt actagtacta ttgaagttat aaaaagtata
    74581 tgtgaggcat atacaaaatc agaaacagat ataaaagttt atagtgatga atttacattc
    74641 gtattgagtt ttatagcaaa taattgtgac tataaaactc ttttagattg tagcgatatg
    74701 attgaaagag taaaacctgc tcacttatta cactatttag aaccaataat actagataaa
    74761 agtatggtct attgtggtgg aggtatggta tgtagtgaag aagtaaaagt tcatccatac
    74821 tttgaaccaa ttataaaatg tagcgctgtt gtaaactgtg gagctggaat gttaagtaga
    74881 gaagaaataa aggtttatcc tttaagcatt aaatgcattg aaaataattg taagattaat
    74941 atagctattg caaatgatac aggcgtagaa aatgtagtag tttatcctaa atcggaggtg
    75001 gtataattgg aagaaaaatt ttatataata ttaaccaaaa ttggtagaga aaaaatagca
    75061 aatgcaactg cactaggaga gcttgttgga ttaaccaagt ttcaagttgg agatagtaat
    75121 ggagaatatt atgagccaac agaggaacaa actgctttaa agaatgtagt ttgggaagga
    75181 aatataaatt ctctaagaat tgatgaaaaa aatcctaatt ggatagttat agagactatt
    75241 ttaccaggaa cagttggtgg atttatgata agagaagctg ctgttctgga taatgagaat
    75301 aatataatag ctataggtaa gtatccagag acgtataagc cacgtgctga agatggcagt
    75361 attaaagatt tggttgtaaa aatgatttta caattgtcca atacttcaaa tgttacatta
    75421 gaagtagacc cgacgttggt ttttgtaact caaaaggata ttcaagattt agatgataag
    75481 gttgataaaa atataaaaga aataaaagta aaaattggag aagaactctt atctacagaa
    75541 gctaaaaact tatcaggagc tataaatgag gtagtagaaa aaattaaaaa tatatctatt
    75601 gatgatgtaa taggaggtca aatacaaact gaactatctg tattaaaaaa tagttacaat
    75661 aaattatctg aaaaagtatt agatatttta atatacttag aattagagtc agaaatagat
    75721 gtagatgaag ctggatattg gtatgatacc ttaactaatg ctaaaaacat aatagctata
    75781 gaaggcctta agttagattt aaatagaaag tgtataactg gagaacttgg tagtgttaca
    75841 tttaagaatg tggttctacc atttaatgca aatagagtta gatatataca tgaaatggat
    75901 aataactttg ttgaaacaaa atctaatagg gcatattcaa ttggccagac agatataact
    75961 ttaaataaat attcgtatga aataagataa ttaggaggtt tttataatga aaagaactaa
    76021 actacttcaa agaggtaatt tctttggcga taaaaatatg gtagttgatg aatttgatga
    76081 agggtatgat aattatgact ttattaattt ttttactgga tgttgtaact atacatttgg
    76141 tctaaaaaat aataatatct tgtatggatg tggagataat agtaactttc aacttggatt
    76201 gggagaagac aatacaacaa gaaaattatt tacgaaaata ccaaatatat ctactaatat
    76261 taaaaaagtt gcatgtggag aatctcatgc agttatactt acttcagatg gagaattact
    76321 tgtcgcaggt ataaatacag atggtcaaat gggattggga ttagaaaaag taggaaaaac
    76381 agtttccaca tttgagaagg ttccagaaat aaaaggcgta aaggatattg catgtggact
    76441 tcaatcaaca tatcttttat acaatgatgg aactttatat gttgctggaa ataatttgta
    76501 tggtcaatta ggtctaggaa ctaatggagc atctgcaaat gtaaatacat ttataaaagt
    76561 agatgttgat aatgtaaagg ctgtattctc atataataaa tcagctttta taataaagaa
    76621 tgacaataaa tgttattcta ctggttttaa taatcaaggt caactaggtt taggagataa
    76681 gaataataga gatttattta gcttagtttc tattaatgat gttaagacta tagcttgtgg
    76741 ttctgaacac actgtgttaa tgacgtataa taatgatata tatggttgtg gaaaggaaaa
    76801 atgttttgga aatgcacttc aatcatcact atttactaag atagaagaag taaatataaa
    76861 aactattgca tgtggtaatg gtaatactat gcttatagat aataaaggta ttttgaaggt
    76921 tgctggaaat aatgatatat atcagttagg tatagcaaat tactctgaga atatagataa
    76981 ttcatttata gatttaaaaa atattgtagc taagaatatt ttcattggtt tatcacatag
    77041 catactaatt gattcaaata atgattcata ttgtacagga gataatactt atggacaatt
    77101 aggttcgttt tttgatgata tgcacattgt agaatttaag aaaatggata gtgaaaaata
    77161 tagttatagt aattatataa atttaattaa atctgaggat aaattaactt tattaaaaga
    77221 agaaatggaa ataaaggata ttgaacttcc actagatata cattctgtaa gagatgtcgt
    77281 ttttagtcct tattgtactc tggttatttt agggaatgga gatgtatatg gtctaggaaa
    77341 taatagatac aaaggaatgg gttctgactt accaagtcaa ttaaatgagt tgacaaaatt
    77401 aagtatctct aatgtaaagt ctatagtagc atcaaaaaat atttctggag gaatattcta
    77461 cattaaaaat gatgacactt gttattattc tgggccaaat agtaactcaa tagcaggtgt
    77521 tcttccttct aattcagata tatttaagaa aatatctata gataatgtaa aaaaagttgt
    77581 tataaatact gatttatcaa actggttttc attaattgta actaataata agcaaatata
    77641 tacttctgga aagagttcaa gttatgttaa tggacttagt aataaatcag caagtcaata
    77701 tactgagatt ggtgttagca atgtaacaga tgcatatagt tcatataatg caacatttat
    77761 tgtggctgac gaaaaaaagg tatatgcaac tggtataaat acaaactatt tattgggtgt
    77821 taatcctaat gatggagtca atataaattt aacattaata aataactggt tttatgtaaa
    77881 tccttcagga gcaagttata gtacaaattc ttgtacaaat gatattacta aaattaataa
    77941 tattattata tatgaatata tggctatatt atgtacaaat tatggttctt ttttaactgg
    78001 ataccatggt actttatgga caaagccaag tgattctact tatagagttc aacaacaagg
    78061 aattacacat gctggatata ttagtaatta catatataac tattatccca caaggtgtac
    78121 acaatcatca tattctacaa attttgccta tttgtattat ggagaatcaa caagtaattt
    78181 aaaaaatgta aatccagata atttacttat ttctggaggt tcatcttata tacatcaata
    78241 tggaaggaat tatcttaaca atcaatcatc taataatatt gcagcatcta atataaattc
    78301 aggtcctatt acctctgata aagccatatt tttatataaa gctctattgt atttatcttc
    78361 taacacgtta tatggttttg ggaatatatc tgaaagtgca aaagaactag atgtttcaga
    78421 tacacaagat ggatataatg ccactaatta taaaaaggta atgaaaaata taaaaaatat
    78481 atttatacct ccttatgatt taagtagaga taaaactaga tttgcaatat taactgataa
    78541 gagcttattt atatgtggat ataactctaa gggtacgcat ggtatatcag ttaatagtag
    78601 tttaaattta aataataaga taaattacaa taaaaagaat agcagtagtg aaatatcttc
    78661 taatatacaa gaaatatata gccattcgaa gtctacatat ttattaacta ataataatat
    78721 gctttacagt gttggtttaa atgatgtagg tcaattagga gtgggagatg agataaatag
    78781 aaaggtattt actaaaataa atattgataa tataaaatct ataaatgtaa atagatttac
    78841 tgacaatagt aaacatgtat ttgcgataaa aaatgataat acctgttatg ctgttggttt
    78901 aaataattct ggtcagttag gaataggaga taatgtaaat agaaatgtat ttactaaaat
    78961 aaatgttgaa aatgtaaaat atgtagctgt atatggaaac acatctctat tattaactaa
    79021 tgatggtctt ttatatggag caggtaataa tggaaaagga cagttaggat tgggtgatac
    79081 tacaagtagg aatatattta cacgtatacc tataaatgga gttagagatg tgtatatatg
    79141 taatgatgta tcaataattg ttaaaaatga taatacatgt tatgtatgtg gatttgtaaa
    79201 tggatatttt gggtttactg aaggaagtat aagtacattt acaaaaataa atattgagaa
    79261 tgtaaaatct gttgtaacag caggaagtga agctacattt tttataacaa atgacaatgt
    79321 tatttatact acagggaaaa aagagagggt attcttttca acagaaacta atgatataaa
    79381 gggtatacga gtaattaata atattataaa tgcaaaaaaa atagtagtta atggatatac
    79441 ttcagccatt ttaacaaatg acaataaact atttgttgga ggtcttagtg gatatggaag
    79501 tatagcaaat aataataata caaatagtgt ggaagatgtt aaagatgttt ttgtaacagc
    79561 taataataca ctttatatag ataataataa caatttgata tcatcaggta gagatactta
    79621 tggtatatct gatgaatctt atagggatat gtcagttcca tattataaag tatctataaa
    79681 gaaagatgtt gatactgtat tttctagtta caatactata tttattaaag atatatatgg
    79741 aaaattttat tcttcaacag gagataatag atataatcat ttaggtattc accatagata
    79801 tgataatgat aaaaatgaag ctcttgaagg ttccctacat tcatatttta aaacagataa
    79861 cacatcagat aaaatagttt ttaataagaa aaatgaaaag ctagtaatgt ttaatgataa
    79921 gtatataaaa acaaataata agtatataaa ttataaaaac atatttaaag ataattttaa
    79981 gtatacttca ataatattgc catttgaggt atctgatatt gatatatcaa aaacacattc
    80041 attggctgtt gctaaggatg gcaagttata tggaatagga agtaattcat ataaagaaat
    80101 taatcaaacc cttgaagata tagaattatt aactcttact gaagtaaata tatcagatgt
    80161 caaaaaagtt gcttgtggag ataactactc ctatattatt aagacagata atactctatg
    80221 gtcatatgga aagaatactg agtaccaatt gggagttggc cacaataatg atgtaagaga
    80281 gttacaaaag gttactggat taccttctgt taaagatata agtatatata actcaatgac
    80341 acttgtttta actaatgagg gagagttgta cgctcaaggg tacaatacaa atggattatt
    80401 tggactagga gaaagtgaaa aagataagat aataagaact tttactaaag tattaactaa
    80461 tgttaaagaa attaagtcac ataatgatga ccacatacta gtaattaaaa atgataatag
    80521 tctatggata actggtaaaa ataaatctat gtataaaata tctatatcaa ttactgattt
    80581 atatgaattt actaaaatac caattcctga acatctaaat gatattttag atatagagct
    80641 ttcagatgat acaatataca tgataacaaa agtagataca agtaaagcat ctatagaaat
    80701 agttgaaaaa tcaatatctc aagtgagagt tgtagtacaa gaccctaata atgttataga
    80761 aaaacttgaa atgtttataa atgatgaatt aatatctact aagactaatt tggaaataaa
    80821 tagcattata tttgagatac cacaaaataa aatagtatta ggagaaaata agatactgat
    80881 taaagccagt agtcctacag gcgatttata ttcaagtatg tttatattta aatcagaaac
    80941 agggcttaaa gtaaaaaagg attctatttt aatgataaac aataaagtat attcaatcat
    81001 aaacattact gaaaataaca ctgatttaat agtaacatta aatgagggat taaaggatga
    81061 catgatggaa aacaatccta tatatcaatt aataaataaa actaaagttc aagtaaaaat
    81121 aaataaatct gacttattca aagacatgaa actagttgaa atcaaaaaat cagactcaag
    81181 ttaccaagaa atctatgaat tagaagaagc caacataaaa agtgctcagc ctaaaatcat
    81241 agtagaaaaa ggagataaat ggacagctat aaaacgtcca tctatgattt ttagatatga
    81301 tgctgaaagc aacgagccac aagcttaaaa tggaggtgtg aaaattgttt aaattcgata
    81361 aaaataaaat agaacaaatc aaacaaggta gaaaagtaga aatgcagtat aaagacattt
    81421 cagacataag tataggtcaa gtaaagcaag atgatgatat aacaaataat tttatagcaa
    81481 atgcagaaat atatgagatg ttgttaaatc aaagttctgt caatgaagca agtaatataa
    81541 gctcttttag tgtaagaaaa tctggaggtg agagtggaat ggtagaagta tatgtagctt
    81601 taattttaag aggcaaaaaa acaatagaag aagtaccagc agtaattaga gagcaagtta
    81661 gaattagatg caaagaatta gaaataccag ttgaatagta aatttagaat aactatgtat
    81721 tagttatttt ttttatgtaa agtacaaggt cttaacttta ataagtaagc cttgtactta
    81781 ttttttgtta tattagaaat tgtatatata tttattattt attcaatcta taaattgcac
    81841 ctacaattta aagtacagaa gattaaattg ataatcctga aaatataata ttgcatgatg
    81901 taagaatata acaaaaatta aagctataag tataaaaaat ttagacaata ggaggctata
    81961 atggataaat taataaccga attgagtagt ctaggggcaa taggtatact atgtgctcta
    82021 ttatttaaaa atactatgca ggagaaaaaa gaagatagag acatgtataa aaaaactgta
    82081 gaaaatttta tagaattatc tacacaacaa caagaaataa acaaaaatat acttgttcaa
    82141 atgggtataa tgaaaacaga tgtagaggaa attaaggaag atgttactgg tataaaaggt
    82201 atgttacaaa acggtgtata acatgaaaga gtagcaccag attatatatt gttaggaaaa
    82261 gataaagtag tattgtagat agtaccctat tttattgaga aggatttgat atttaaaaat
    82321 attaattaaa aaaagtaata aaaataatat ataaaaataa tatataaaaa ttaaaaaagg
    82381 agttgagctt aaatttgatt agaaaaaatc aattttaaga caactccttt tttttattaa
    82441 attattgtct attaaccaaa atagctattt tagcatctgg attataactt atttgaacca
    82501 tttgattttt cttaacatgt tcaaggtctt caccaccata agctatttgt aacttaactg
    82561 gtaacttacc ttgttttata atagcaacgt actctttttt accttttttc tctaaactaa
    82621 tcaaattgcc aacataaggt ttaaagttct gatacttttt actagaattt cttatgtaga
    82681 agaaagcacc aacagcaata actaaattta tgccaagtgt aacccaagaa ttgattttaa
    82741 gcatagctcc agcgattatt atcacgaaca ttaaaacgat aggtaatata gctttcttaa
    82801 gaagcaattt acccattatt tcattagcct ttttctcagg gccactcata gtttttgatc
    82861 tagcaaatga ttgcgcgaat ttgtctctta agcccatttt atcctcctaa ttttaataaa
    82921 tatttagtta taataacgag atattacttg aaactaaaaa tttactacat ttatattatg
    82981 tttgactttt gtataaataa ttacattcaa gtaaagcaaa atatactaat tattttatca
    83041 taaaattata aaaaagaaaa taaatgaaat aaaaatatta gaacaaagaa atgatgtaaa
    83101 atcgtatcaa aagcaacata aaaattattt atctattttc tcatctttat ttttgttata
    83161 ctcaattttt cctaaatcct tctctttttc atattcatga agttttaatt caatcatacc
    83221 ttctattttg gctttatcat aatcatttaa ctttctaaaa ttgtttaaaa gctttatttc
    83281 attagagttt atgctattaa gtggatagtt tgaggaggaa tcgcaaatta aatctgattt
    83341 atgtgataga ttatctccat ttaatagcca gtctactgaa acattaaata tctcagctat
    83401 agattttaat atttcataat ttggttttct aatgtttctc tcaaatttac ttaagttgtc
    83461 acagcccaac atttcttcta gttcatattg tttaaggttt tttgcttttc tcaaataaac
    83521 aattctttct cctaaagtat ccataaacac tctccattca attaatgtca aaaagacttt
    83581 ttaagatgta aatagtttca aatttaaggt caaaatgaca taaaaagcat tgacttaagg
    83641 tcaaaatgac tttataatta acttaatgat acgaatttac atcctaattt tagcacaaag
    83701 taatcaaaaa atcttattta gtattaaata aatttatata cttaatatgt gtacatatta
    83761 aaaatatata ctaaatagag ggggtgtgta agctaaaata atataaaagt aaatataaat
    83821 cacttagaaa ggaagttgat aaatggatgc tcgaaaaaaa tggatacctt ttttgggagt
    83881 gcaagtcaag caaagactta ttgaattaaa tatgactcaa agggaattag cgaagaaaat
    83941 aggtgttaat gaaaactatt tgtcagctat tttaaatgga agaagaacag gtaaaaaata
    84001 taaatcatca atttatcaat tacttaatat agaatattca gaagatgatt aataaatagt
    84061 atataaagta ggtgaatatt cttgtgtgta aattggattc agatggggtt atagagtgtt
    84121 gtagagcaat tgatgatttt attacagcac tcagtaatat aaaaagctta aatatggaaa
    84181 gattaaatac tttaactaaa tattctagta catgttcaat ccttcttaaa gaggggaatt
    84241 atgaaggatg tacaattgtg tatagaaaga tgttggaaga attaaaaaca tgagtaatgc
    84301 atttcttagg aatataagtt atacatagag atgtattata tttttcaaag tacttaaact
    84361 aaaatatgga taagataatc taaatattat aaatgtgctt gaaattagac tatacttgtt
    84421 tttaaataat ccaatatcca tattttagta atatactaca aaaaaagaag gttaatagat
    84481 gatgtaaaat cgtatcaaat tatgtatgtt taaaccattt tatcttcatt attattagag
    84541 gaatgctttt ttaagtcttt atattcagat atcttaagtt caagtattcc ttctattttt
    84601 attttatcac gttcgtttag ttgtctgtat agatttaata tcgtcatttc atcattagta
    84661 acatgtaagt aatcttcttt atcttctttt acactactat tgacatttac cttctcttta
    84721 ccatagagaa gccagtcagt cgtaacatta aaataatcag ctattgacat tagtatatca
    84781 caattaggtt ttctatctcc tgtttcatac ttgcctaagt tttcaaattt taaaatatcc
    84841 ataagtttgc gctgagtaag ttttttggag tttctcaaat aagcaattct ttttcctaaa
    84901 gtatccacaa aatacactcc tttcttttta tgagtaatgt ctaaatgaca tttaaaatta
    84961 aaaatatata aatttataat ataaaactac taaattaaag tctaaatgac attttgctta
    85021 aattaatatg ctcataatat gattttaaca tattatagtt gaaaatatat ggtttatttt
    85081 gatttgtata tataacaata ggtttaattg ttatataaat gtaaaggggt gtatgaatag
    85141 attgtataaa tttatttcga taaactaaga ttgctttttg attgtctgta aaagagaaaa
    85201 agattaagag aaaaatagta ttatatt
//
LOCUS       DAMJWC010000008        81272 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMJWC010000008 DAMJWC010000000
VERSION     DAMJWC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.008"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            277..654
                     /locus_tag="PC503_000707"
     CDS             277..654
                     /locus_tag="PC503_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2526722.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            647..1795
                     /locus_tag="PC503_000708"
     CDS             647..1795
                     /locus_tag="PC503_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2526723.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            1812..2414
                     /locus_tag="PC503_000709"
     CDS             1812..2414
                     /locus_tag="PC503_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2526724.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2507..3529)
                     /locus_tag="PC503_000710"
     CDS             complement(2507..3529)
                     /locus_tag="PC503_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2526725.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3858..4040)
                     /locus_tag="PC503_000711"
     CDS             complement(3858..4040)
                     /locus_tag="PC503_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526726.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4353..4772
                     /locus_tag="PC503_000712"
     CDS             4353..4772
                     /locus_tag="PC503_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF2526727.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            4903..6744
                     /locus_tag="PC503_000713"
     CDS             4903..6744
                     /locus_tag="PC503_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2526728.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6771..8658
                     /locus_tag="PC503_000714"
                     /pseudo
     CDS             6771..8658
                     /locus_tag="PC503_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            8666..10666
                     /locus_tag="PC503_000715"
     CDS             8666..10666
                     /locus_tag="PC503_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526729.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            10928..12187
                     /locus_tag="PC503_000716"
     CDS             10928..12187
                     /locus_tag="PC503_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2526730.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            12248..14035
                     /gene="iorA"
                     /locus_tag="PC503_000717"
     CDS             12248..14035
                     /gene="iorA"
                     /locus_tag="PC503_000717"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF2526731.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            14037..14612
                     /locus_tag="PC503_000718"
     CDS             14037..14612
                     /locus_tag="PC503_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF2526732.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14665..15735
                     /gene="buk"
                     /locus_tag="PC503_000719"
     CDS             14665..15735
                     /gene="buk"
                     /locus_tag="PC503_000719"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2526733.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            15953..16654
                     /locus_tag="PC503_000720"
     CDS             15953..16654
                     /locus_tag="PC503_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526734.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            16714..17220
                     /locus_tag="PC503_000721"
     CDS             16714..17220
                     /locus_tag="PC503_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF2526735.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            17395..18417
                     /locus_tag="PC503_000722"
     CDS             17395..18417
                     /locus_tag="PC503_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2526736.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18564..18872)
                     /locus_tag="PC503_000723"
     CDS             complement(18564..18872)
                     /locus_tag="PC503_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2526737.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(18932..19360)
                     /locus_tag="PC503_000724"
     CDS             complement(18932..19360)
                     /locus_tag="PC503_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526738.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(19583..21040)
                     /locus_tag="PC503_000725"
     CDS             complement(19583..21040)
                     /locus_tag="PC503_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2526739.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            21458..22372
                     /gene="nadA"
                     /locus_tag="PC503_000726"
     CDS             21458..22372
                     /gene="nadA"
                     /locus_tag="PC503_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF2526740.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22385..23686
                     /locus_tag="PC503_000727"
     CDS             22385..23686
                     /locus_tag="PC503_000727"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF2526741.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23667..24503
                     /gene="nadC"
                     /locus_tag="PC503_000728"
     CDS             23667..24503
                     /gene="nadC"
                     /locus_tag="PC503_000728"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF2526742.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24759..25091
                     /locus_tag="PC503_000729"
     CDS             24759..25091
                     /locus_tag="PC503_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF2526743.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            25253..25438
                     /locus_tag="PC503_000730"
     CDS             25253..25438
                     /locus_tag="PC503_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526744.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25465..26550
                     /locus_tag="PC503_000731"
     CDS             25465..26550
                     /locus_tag="PC503_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2526745.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26543..27001
                     /locus_tag="PC503_000732"
     CDS             26543..27001
                     /locus_tag="PC503_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526746.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            27036..28127
                     /locus_tag="PC503_000733"
     CDS             27036..28127
                     /locus_tag="PC503_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2526747.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            28132..28356
                     /locus_tag="PC503_000734"
     CDS             28132..28356
                     /locus_tag="PC503_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526748.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28366..28929
                     /locus_tag="PC503_000735"
     CDS             28366..28929
                     /locus_tag="PC503_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526749.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            28890..29519
                     /locus_tag="PC503_000736"
     CDS             28890..29519
                     /locus_tag="PC503_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526750.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            29696..30448
                     /locus_tag="PC503_000737"
     CDS             29696..30448
                     /locus_tag="PC503_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526751.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30461..30946
                     /locus_tag="PC503_000738"
     CDS             30461..30946
                     /locus_tag="PC503_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526752.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            30953..31102
                     /locus_tag="PC503_000739"
     CDS             30953..31102
                     /locus_tag="PC503_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526753.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(31238..32059)
                     /gene="yidA"
                     /locus_tag="PC503_000740"
     CDS             complement(31238..32059)
                     /gene="yidA"
                     /locus_tag="PC503_000740"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF2526754.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32552..34246
                     /locus_tag="PC503_000741"
     CDS             32552..34246
                     /locus_tag="PC503_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF2526755.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYIRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34578..34688
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            34792..35163
                     /locus_tag="PC503_000742"
     CDS             34792..35163
                     /locus_tag="PC503_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF2526756.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            35258..36205
                     /gene="trxB"
                     /locus_tag="PC503_000743"
     CDS             35258..36205
                     /gene="trxB"
                     /locus_tag="PC503_000743"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2526757.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36309..36626
                     /locus_tag="PC503_000744"
     CDS             36309..36626
                     /locus_tag="PC503_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF2526758.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            36895..38181
                     /locus_tag="PC503_000745"
     CDS             36895..38181
                     /locus_tag="PC503_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2526759.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            38293..38766
                     /locus_tag="PC503_000746"
     CDS             38293..38766
                     /locus_tag="PC503_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:38425..38427,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF2526760.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            38798..40108
                     /gene="grdB"
                     /locus_tag="PC503_000747"
     CDS             38798..40108
                     /gene="grdB"
                     /locus_tag="PC503_000747"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:39845..39847,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2526761.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            40364..41896
                     /locus_tag="PC503_000748"
     CDS             40364..41896
                     /locus_tag="PC503_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF2526762.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            41907..43052
                     /locus_tag="PC503_000749"
     CDS             41907..43052
                     /locus_tag="PC503_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF2526763.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            43362..44441
                     /locus_tag="PC503_000750"
     CDS             43362..44441
                     /locus_tag="PC503_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2526764.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            44554..45153
                     /locus_tag="PC503_000751"
     CDS             44554..45153
                     /locus_tag="PC503_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526765.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(45339..46211)
                     /locus_tag="PC503_000752"
     CDS             complement(45339..46211)
                     /locus_tag="PC503_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2526766.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            46628..48031
                     /locus_tag="PC503_000753"
     CDS             46628..48031
                     /locus_tag="PC503_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526767.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            48058..49602
                     /locus_tag="PC503_000754"
     CDS             48058..49602
                     /locus_tag="PC503_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2526768.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            49633..51024
                     /locus_tag="PC503_000755"
     CDS             49633..51024
                     /locus_tag="PC503_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF2526769.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            51217..52713
                     /gene="abfD"
                     /locus_tag="PC503_000756"
     CDS             51217..52713
                     /gene="abfD"
                     /locus_tag="PC503_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF2526770.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            52848..53123
                     /locus_tag="PC503_000757"
     CDS             52848..53123
                     /locus_tag="PC503_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526771.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            53147..54454
                     /locus_tag="PC503_000758"
     CDS             53147..54454
                     /locus_tag="PC503_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2526772.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            54474..55592
                     /locus_tag="PC503_000759"
     CDS             54474..55592
                     /locus_tag="PC503_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2526773.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            55879..56799
                     /locus_tag="PC503_000760"
     CDS             55879..56799
                     /locus_tag="PC503_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF2526774.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            56914..58071
                     /locus_tag="PC503_000761"
     CDS             56914..58071
                     /locus_tag="PC503_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2526775.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(58156..59655)
                     /locus_tag="PC503_000762"
     CDS             complement(58156..59655)
                     /locus_tag="PC503_000762"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF2526776.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            60251..61675
                     /locus_tag="PC503_000763"
     CDS             60251..61675
                     /locus_tag="PC503_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF2526777.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            61710..63839
                     /locus_tag="PC503_000764"
     CDS             61710..63839
                     /locus_tag="PC503_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2526778.1"
                     /translation="MKKKKITSRQKKIILMIVANSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEWVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDVVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            63869..64291
                     /locus_tag="PC503_000765"
     CDS             63869..64291
                     /locus_tag="PC503_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2526779.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            64310..65461
                     /locus_tag="PC503_000766"
     CDS             64310..65461
                     /locus_tag="PC503_000766"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2526780.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      65567..65668
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            65851..66423
                     /locus_tag="PC503_000767"
     CDS             65851..66423
                     /locus_tag="PC503_000767"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF2526781.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            66487..67137
                     /gene="fsa"
                     /locus_tag="PC503_000768"
     CDS             66487..67137
                     /gene="fsa"
                     /locus_tag="PC503_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2526782.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            67289..70213
                     /locus_tag="PC503_000769"
     CDS             67289..70213
                     /locus_tag="PC503_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2526783.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVMKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            70802..71260
                     /locus_tag="PC503_000770"
     CDS             70802..71260
                     /locus_tag="PC503_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2526784.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            71321..71596
                     /locus_tag="PC503_000771"
     CDS             71321..71596
                     /locus_tag="PC503_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2526785.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            71655..72929
                     /locus_tag="PC503_000772"
     CDS             71655..72929
                     /locus_tag="PC503_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2526786.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            73059..74111
                     /locus_tag="PC503_000773"
     CDS             73059..74111
                     /locus_tag="PC503_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2526787.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            74111..75142
                     /locus_tag="PC503_000774"
     CDS             74111..75142
                     /locus_tag="PC503_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF2526788.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            75234..76046
                     /locus_tag="PC503_000775"
     CDS             75234..76046
                     /locus_tag="PC503_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2526789.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            76049..76969
                     /locus_tag="PC503_000776"
     CDS             76049..76969
                     /locus_tag="PC503_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2526790.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            77144..77590
                     /gene="rpiB"
                     /locus_tag="PC503_000777"
     CDS             77144..77590
                     /gene="rpiB"
                     /locus_tag="PC503_000777"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2526791.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            77620..78285
                     /locus_tag="PC503_000778"
     CDS             77620..78285
                     /locus_tag="PC503_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2526792.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIEPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            78395..79897
                     /locus_tag="PC503_000779"
     CDS             78395..79897
                     /locus_tag="PC503_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF2526793.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(80209..>81272)
                     /locus_tag="PC503_000780"
     CDS             complement(80209..>81272)
                     /locus_tag="PC503_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2526794.1"
                     /translation="VFFSNLLNMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYI
                     YYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGD
                     DEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKN
                     NDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIV
                     EFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFI
                     KEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHM
                     EIIIDADLFKVMLTFRRVN"
BASE COUNT        32129 a         8845 c        14653 g        25645 t
ORIGIN      
        1 attttaaaaa aaagtattat aatattcctt gtgtgaaaat ataggaattt ttattaaata
       61 gttttaatgt gtaaataaca ttctacacta ttgtaattaa atatgtaaaa agtaaaatat
      121 ttaaatagat atattttaaa atctaacttt taatattgta aaaaaattag aaatttaaca
      181 aaaagtacaa aaattcacat ttttttcata aagtgtttga ctaaaaaatt cacatgttgt
      241 agaattaagg tagcaggagt tttgagggag gtgtaaataa tgataagaaa aataccacaa
      301 gcagaactaa aagtaatgaa attcatttgg aaagtagatg ttacagtgac atcaaaagat
      361 gttattgaag ctatggaaca aaaatatggc tggaaacaaa ccaccacact gacactttta
      421 tctaggctgg taaaaagagg attcttagat gctcaaaaaa tagacagata tacacattac
      481 acaataagag taaaacacaa agattattta agttttgaga caaaggattt cctaagtaat
      541 atacatgatg actctttaag aagcttaatt tcagcattac atgatgatga aaatataggt
      601 aaagataagc tagattttct agaaagttat tttgataatt taaaggatga ataattatat
      661 gctatatgtt tttgaaaatc ttataaagac aactattgta tgtagtcttg gtatttgtct
      721 attattattt ttgaaaagat atttatttaa gaagtttagt aagagattca attattatat
      781 ttggttgata atagtcttta gaatgttact ttttctattt aattatacaa tagtgtatga
      841 agtaaaagaa cccaaagaaa atgcattagg aaataatatt acacaaattg atatttctac
      901 agataataat cttatgctgt atgtagctta tttatggtta tttgtaacta tagtcattgc
      961 agtttataca tttataaagt atacaagatt taaaaatcta gttgttgatg tatcttatga
     1021 tattgaagat aatgatataa actgtatcta caaaaacttg ttaaaagaat taaatataaa
     1081 aaagaaaatt gaattaagag gttctgatga attgataagt ccagcaggta tgggattatt
     1141 taaatcttac atattcttac cagactatcc ttatagtaaa gatgaactaa cttggatttt
     1201 gaaacatgaa ttaatgcatt ttaaaaataa agatatttta ataaagtttt tagttttgtc
     1261 tgttagaata atatattggt ttaatccact tgtatatgta atgagcaata aagtaaatct
     1321 agattgtgaa ttatgttgtg atgaaagtgt tttggtagaa tgttctttaa aagataaaaa
     1381 agaatatgca ctagcactta taaagtcaat taagtttagt aaaaattata atagtaagat
     1441 tttgacaacc gagtttgata agacaaattt ggaaaagaga cttgagagta ttgttaaaaa
     1501 gaaaggcaaa agtggaatac taattgctgt tttagtattt atgacttcta taacatcttt
     1561 tgttgaagtt gatgctcaag ttagaattga tgagggtaat aatggaatga ataacaatat
     1621 taatgaattt ttattgaata agacgactga taaaattata aatatttatt ataaagatgc
     1681 accaaatgaa attaggaaat tttatgaaga taaatgcgaa ttagaaggta aaatacctag
     1741 agactatgac ataatagaaa tggatatgaa agattataat caattaataa aataattata
     1801 aggaggattt tatgttaaca aaattaagaa aaatagtagc tattatgtgt tgcttattgc
     1861 ttacttttac aagtgtggca tttgctgaca caagtaaaga gaaaggagga agtaaagaga
     1921 ctgttccaga gaaaaaccta gattctttta ctctttctgg gtatatatat acatatgaaa
     1981 atgcgccaca agaaataaga gatgaacata aacaaaattg tgaagagata aatatagacc
     2041 ctaagccaga tgatgagata tttgttccag aatcagctaa tctaatgaat gaggacaata
     2101 gtaaaggtgt ttatgcaagt tatactgttt cttataatat aggtgctaaa actataacaa
     2161 ttatgagtaa tgagtatttg actataagta caacaaaagt tatacgaaag ggtaatagcg
     2221 gaaaagaagt aaaagctgca caaatcatgt taactttact tggttataat gtaggtatag
     2281 atagttcttt tggaagtaag acatataatg cagttgtaag tttccaaaaa aaatacggtt
     2341 tgtctgcaga tggaataatt ggtccagcta cttgggataa attgggtaga ctaactgacc
     2401 ctactctttc ataggattaa aatctaaaaa tatattaaat agtgtctcaa tatgattttt
     2461 caatttaaat gagacactat ttaaatataa atgttataaa actattttac aataaattcc
     2521 atataactct accatctata tccttaacat tttgacaacc agtcaaaatc atagtctcac
     2581 ataactcatt cctaaccttc tctataaaaa actccacacc atcaagacca ccgccaaaag
     2641 aagcagtaac aaaaggtctt cccatcaaaa cagcatcagc acccaatcca agcatcttaa
     2701 ctacatcaac accagtccta actccaccat caacaagtat tgttatcttt ccctttacag
     2761 acttagctat atctggaagt acctcacaag taccaggagt ataatcaagt actcttccac
     2821 catgatttga aacaataatg gcactagcac cagactctac agccatcaaa gcatcatcta
     2881 cagtcataat tccttttata ataaaaggta atctagtgga ttcaaccaat tctctaatct
     2941 catcaattgt tttaggagaa aaaggatttt cttgaaattg attattaata agtccacaag
     3001 catcaaggtc tacaccaact gcaaaagcac ctgcttcttc agacaatcta attttatcta
     3061 ttatctttga attattccaa ggctttataa atacaattcc atttccccta ttatccttca
     3121 atacatctaa attatccagt aaaaaagtat ctacattagt atcgccaacc atagcataaa
     3181 ttccagaatt agaacaacct ctaacaacag gctctatgta ttctttttcg gaaactttac
     3241 cacccatgtt caatatagta cctgatacag gtgcagcgaa tataggagaa ctcatttttc
     3301 taccaaataa ttctatggat gtatctggct ttgaaacatt atgtatgact ctcatattta
     3361 tctttatttt ttctagactt tttctatttt caatgaaaga cgaaccactt cctttaccac
     3421 ccataccagg aacatctcca gcacaagcta atccattaca aattttacat actttacatg
     3481 ttccattaaa gttctctcta gctgatttta gtaagtcatt gtaatccata caaaatctct
     3541 cctttttata atattaaaat tgagtattac tatattgaaa atatcttaat tgtaaatata
     3601 gggatgttat tatgatgagc taaactagat aatacatatt agatattttt tattgttgta
     3661 gatagttaaa ttatatcata ttagatagtc aaattttgaa aaaaactaac ttatttaagt
     3721 atacattttg aaaaaattaa aaaagctata tatagatttt taaagaaatc tatatatagc
     3781 ttttaagttt atgtcaatct tttttgttaa tgaataaata atatagaata caatatacaa
     3841 aaaagtttct tgaaatgcta agataatccc catttacaaa gcaacatcat tatactgtgt
     3901 aaatttgaat caacaatgtt ttcaccatat ttcatcataa aatcctctaa ttgtgtgtca
     3961 ataaatgaat aatatccact tatactatcg atgtatgcag tcattaagtg tatacattca
     4021 tcacttttat ctttatacat atatatctcc ccctatatac aatatataaa tttagatacc
     4081 aaatcgtatc atattaaata gttaagtgtg taacatctat gcagttatat atttatatca
     4141 ttatattaat aactaaagtg agttttgaca atagattttg ggaaactgga tgttcaaagt
     4201 gcaaacttgg attttaaaat cattaattaa gatagcgcat aggaatatat gtatacataa
     4261 cttaattata aagattataa acaattactt ttattaactt tatttaaatg gtagaataac
     4321 ttggagatta ataattataa ggaggatata atatgagttt atataagttt atatatgatg
     4381 ataaggaata tttattaaaa gaggagaact gtagtgcttt aataaatgat gaagaaaatc
     4441 cagttcaagg agtaagtatt tcaaaaataa ttgatatact taatgaagca gaagaagttg
     4501 attttgatgt agaatattat caagaagcat gtccattatg tttagaagga gtaaaagaaa
     4561 agaaaaaatt ctttcctttt ttagaatatc acttttatat tttcagtaaa gatggagaat
     4621 atgtaataag caatatatct gttgattata aaggactatc ttttaataaa ctatcaaggg
     4681 caaataaagt tgataatagt tatattgtaa gtgtgataat ttgcgaaaat tgtcaggatt
     4741 atatagttca gatagaaaat tgtatagttt agtgtaaagt atgtcttaat ttaagagaaa
     4801 tttctaaatt gagacatcaa cttttttcaa aaatagtatg gaaaattact aaatttatga
     4861 gataatgtaa gtcggaggtg agttacaata tatagtaaat atttggaaga gatagatgat
     4921 acaattttag attcaatgtt taaactaacc ttgaatgaaa gattattgac taataacgat
     4981 tttattgaaa ataaaattga tgtagtaaag aatttaattg attgctataa aactgaacaa
     5041 aatagtttaa tgttattaaa atcaaatttt ttgctagctt tattatatgg tattcaaggg
     5101 tttagtgaaa aaatgaaaga gtatattttg atttcctgta aatatattga taaatgctta
     5161 cccaaagatt ataaattttt agcacgattt tattcacaaa tagctatttt aagtttaaaa
     5221 aatgaagatg taaataaggc aaatttatat atggataaat ttaatcttat ttgtgatgaa
     5281 aataattttc taattgaaga aattattttt aaatcacaac ttatttacat taaggcaagt
     5341 aagtgtatag aatcttctgt aataattaaa gaaatagaaa cgttgtatat aaagataaaa
     5401 gaaattaacg attttaattg taaaaaaata tattttttta ttattggtaa aatatatttt
     5461 ttgtttttgg atgatgctct aattgctaag gtaaattttt taaaagcaag aaaatatgca
     5521 gatttactaa aggatatgca agtatcttca ctatgtaata taaagatagg tgagtgtgaa
     5581 tgttcgtttg aaaattatga atgttccatg gaatatttca atgaagtaat aagcaataaa
     5641 aagtatagaa atgtaaatat aattcaaaaa tatagagcat caaacaacat aactaaaata
     5701 ttaataaaga ctagaaatta tcctgtcgca ataaataatt tagcaaaatc tgaagtatat
     5761 ctagaaaaaa ttaaaaatca tagcttaaaa gaagtagaga agtttgattt atttataagt
     5821 ttagccatgt attatgcaaa aagtaatgaa aaatcttttg aacaatcaat atgctattta
     5881 gatagagcta aaaacatatt aaatatgata aaaaatatag aagaatatat aatatatgat
     5941 ttagaaataa tttatcacca ggcaaagata tattatatct ttggatatta tgacaatgcc
     6001 ttaaatacaa ataaaaaact ccttgaaaaa tctaaaaatg ctaaaaatta taattatgtg
     6061 aagttagcat acaagagtat atatttgtgt tttgaaaaga ttcaaaatta tgaaatgagt
     6121 atgaaatact ttaaaatgta ttatgagtta aaaatgatgt atataaaagc tcgaaataga
     6181 aattatatag attccttaaa ttatagacat gagtatatag aaaaagaaat aaataacatg
     6241 agaaaagtaa aacttgattt agataaaaaa aagtatgttg accatttgac aagtgcatat
     6301 aatagaactt ttttgaacga ttttttagaa aaacaagaag ttagtgaata ttgcacagca
     6361 tttatgatag atgtagatta ctttaaagaa tacaatgata cttatggaca ttataatgga
     6421 gatattgctc ttaaaaatat aactataata ataaaaaaat atctaaaaaa agacatgctt
     6481 atgataaggt atggtggaga agaatttctg atattatctg tatgtaaaga ttataaaaaa
     6541 agtaaaatat ttggaagaaa attatgtagg attgtaaaga aatttttaaa taataatttg
     6601 acagttagta ttggcattga tacatgtaaa aatagtagta tagatataaa agaaataatt
     6661 gaaaatgctg ataaagcttt atataaagca aaggaaagtg gtagaaatag atgtttgcat
     6721 tatcatgatt ttaagaattt ttaactgttg aaataggatt ggtgatttac ttgaaaagga
     6781 gtttaataga agatttaaag agaaatataa acaagataga atacgatatg ttgactaaat
     6841 tctatctaaa tttgacagat ttaaactaca tcttggatta tcacaaagac cttttaaata
     6901 caaaattaga agataatagt agagtctata ctttatattt aattagtctt ataaactata
     6961 taaaaaaaga tagagaagca tcatacaact atttgataga gtcattaaag tatattaaaa
     7021 aattgtcatt aaaagatgat tcagatataa tatctaaaat ttatatttat cttactttat
     7081 cagctatttc tataagaaaa tatgataagg taaataattt ttatttctca gcaaaaaaaa
     7141 ttataaggca aaatcattta aatgagttgt tggtattgtt aaatatgagt ttatgtgtgg
     7201 aaataagtgc tttatatcag accaaaacgg atgtaatagc tttagtagaa gaagtgtctt
     7261 tttttaaaac tttaaaaaat aaagctcttg taagtagggc aaattatata tttgggagag
     7321 tttatctata tttatttaat aactttataa aaagtatgga atacttaatt gaatgtctaa
     7381 aattggctca agaaaataat ttatactcta tagaggcttt ttgtaaatgt ataataagtt
     7441 tgtgttattt agagagtgga aataatgtag aagctataaa atacataaat aatgtattag
     7501 atgttgcaca cagtaataac tcaatatcag taactgaaag agtgtctata aaaatagacc
     7561 ttatatgggc atatttaaaa gaagatatga ataaagaagc agaagttatt ttattaaaga
     7621 ctataaaatt aatgaaagtt gttgaaggtg tatataagga ttatttatat tcatttatat
     7681 ttttatattc agctgaaatt gagttaaaga aagataattg tagttttgaa aaggtaaaca
     7741 cctatttaat tttatcaaaa aatatatata aaagttttgg agatgttttt atatataatt
     7801 ctaaactaga ttacatatat aagttgtatg gagatttata tataaaattt ggtaatatag
     7861 atgaaggtat aagttgttat ataaaaggtt taaatttagt taaaaagagt tcattgaatc
     7921 ttagaaaaat atctatattt atatgggcta atagcaaatg gatatgagct aaaaaaagat
     7981 tttaaactgg caatagaata ttataaaagt atggattggt attctgatag gtgggaaaaa
     8041 aataattcct ataaaacatc tcaagcaatt cacaaacaat atgaactcag acaaaaacaa
     8101 gagagtttaa gattactagt ggatgataat aagaaattag aaaatgatat tttaaaagat
     8161 ggacttacta aactatataa tagaagatat ttggaacagc agttggattt atttaatgga
     8221 accagagaca aaaatatggt cgcaatactg gtcgatatag attgttttaa aagttataat
     8281 gataattatg gtcatctagc aggggataaa gttatagtta aggtaactga tattataaga
     8341 agtgtattta tagatattac cgaacacata atcagatatg ggggagaaga aattttaata
     8401 ttagtagatt ctatagaatc aatcggtgtt gaagagattg ataatataga attatatatt
     8461 aaaagagttt tcaaacttct tgaatttgag ggtattgaac atatatattc taaaataaaa
     8521 aactatataa ctataagtgc tggagtaagt ataaaaaggt gtcgtagtag aaaagatgtt
     8581 gaaatattaa ttgaagatgc agataagaac ctatataaat caaaaaaagc aggtagaaat
     8641 caatacatta taatttaaaa ttgaggtgat tttgttgcga aaaaaaatag gaattatagc
     8701 ctctgatatt gaattaaaag aaagaataga agaattatat agagaagatg tagaaaatgg
     8761 aactataata atcgacatac ttaacctaga cttaatggaa aatcaaggtc gtatacttgt
     8821 tgaaaaaggt gcccaagcta taattggtag aggtggaggt tatagcttag taatagatac
     8881 agtaaatgta cctgttatac caatgaatat gaagtcaact gaccttttaa gagcaataga
     8941 aatagcaaag aaatattcta aaaaagtagt attgattctt ggagacaatg aagtttcttt
     9001 tgactatgtt ggctggagaa atgtcataag tactgaaata actgaagaat ggtttgaatc
     9061 taagtatgag ataagaagta aagttgtaaa atatatagac caaaaagatg aagttgtaat
     9121 cgtaggagga ggtttggcat gttcttttgc aaggcaatat ggaattgata gtgtatttgc
     9181 aactgctagt gatgaatcta taagagaagc tgtagaatat tgtaaaaaat tattagatac
     9241 attaggtgaa gaaaagttta ataatgaagt gttacgaaat atacttgatg gtataaaaga
     9301 tggagtaatt gctatagata gtaatggcag tataattttg tacaatgaaa gtgcaaaaaa
     9361 catgcttaaa gtagagagaa aatgtgcact taataaatac atcttagatg tatttcctaa
     9421 aatggagtgg atgttagatt gtttacatga aaaagaggac gtagaagata gaaagataag
     9481 aaatataaat aatctaattg ttaatactag gacaacattg ataaaagttg ataatagtac
     9541 ttatggagtt ttaggaataa tacaagatat aaccaagcta caaaacttag aaagaaaaat
     9601 aagatttgac ttgaatcaaa aaggtctcta tgctagatat acttttgatg attttttatt
     9661 taaagataaa ttaactaaag aatttattga agaagctaaa aaaattggaa aaagtgatta
     9721 tacaacttta ctttatggag aaagtgggtc tggtaaagaa attatagctc atagtataca
     9781 caacataagt aaaagaaaag ataggccttt tgttgctata aattgtgcta ctatagcaga
     9841 aaatttactt gaaagtgaac tttttggcta tgaagaaggt gcatttactg gtgctagaaa
     9901 gggtggaaaa agaggactat ttgaacttgc tcatggaggg actctttttt tagatgaaat
     9961 aaatagtcta tcctttaata ttcaaacaaa actattaaga gtaatagaag aacgtcaaat
    10021 aatgagaatt ggttctgatt atataatacc tctggatata aggattatag cagcaacgaa
    10081 tgaatcttta accgaaaaaa tagttatggg tacatttaga gcagacttat tttatagatt
    10141 gagtagttta gagataaata tacctccttt aagagacaga agagaagata taataccttt
    10201 gtttaacaat tttgtaaatg aagtattaaa ggatgatggt ctcaatggaa taaacagtat
    10261 agatgaaaat tttgttttga ctaaagatga aatggataag ctatataatt atagctggcc
    10321 tggaaatgta agagagttaa agacaatagc tcaaaaatat gttgtgacag gtaaaattaa
    10381 attgagacaa gatagagatt ttaaaactaa aaaattactt cctaactctg aagtagacaa
    10441 atttaattct gaaacgacag caagtgtaga agtccaagat gaatctataa atataagtaa
    10501 gataaatgat ggtaagataa gtatagatat aaaagaagta aataagtatg ttgaagaaaa
    10561 aataataagt atgctttttg ctcagggact ttctaaaaat gaagttgcac aagttcttgg
    10621 aataagcagg acatctttat ggaagaaata caataaaaat atttaaatat aattacatat
    10681 aaattatttt gaagtaatgt taatttttta aaacaagtgt taagaaaaat taacattact
    10741 tttttgcaaa tttttatttt tttagacagg catatatatt tataagaaaa atagttaaaa
    10801 cacttaattt aataatgaaa aaaataataa ttctaaacaa aatcaatttt acataaagtg
    10861 ggatttattg gcatagtaat tgcttaatat ataatgtaag agtaaataca attttagggg
    10921 tgatggtatg agtcaaagta tggttggtaa gcatgcaatg tggccaaaag aaaatgatgt
    10981 tatatttagc atatctggca gagctcaagc agcagagaag gcttttggta tggataatgt
    11041 aataaatgca acaataggcg ctctaatgga tgattcagga aaattgataa caatgaaaac
    11101 tgtatatgaa gaatataaag cattagataa ctgtgagata ggtgcatatg cagctcttga
    11161 aggtcaacca gattacttag aagcagttaa aaaagtattt ttcagagatt acttaccaga
    11221 aggacatata agagtattag cttcaccagg aggaagtggt gcaataaaat tagctgtatg
    11281 gaactatact aatgaaggag atgaggtatt aacatctgat tggttctgga gtccatatgt
    11341 aagtatagct gaagaggcta atagaaaagt agttaattac caactttttg atgaaaatag
    11401 aaggtttaat tttgagtcgt ttaaagaaaa atttgtaaat atagcagaaa aacaaggtag
    11461 agtctttaca attataaaca caccagcgca taatccaact ggatatagtg ttgcagatga
    11521 tgagtgggat aaaatattag acttatcaaa agaagtcgca aaagataaag acaaaaagat
    11581 aatatttttc gtagattcag catatattga ctttgcaggt gatgatgatg tatgtagaaa
    11641 gttttttaag aaattttcta atttgcctga aaacgttctc gtattggttg gattcagtat
    11701 gtcaaaagga tttacagctt atggtatgag aatgggagct ataatttgta tatcttcaag
    11761 tgaagatgta gctgaagagt tccattactc atgtgttcat tcatgtagag caaattggtc
    11821 aaattgtaat agaagtgcta tggcagtatt atctaacatt gtaaatgacc ctaaaaaatt
    11881 caaagaatat gaggatgaaa aagaaatata caaaaacatg cttactagaa gagcagatgt
    11941 atttgtaaaa gaagctgaaa gagtaggatt agaaattctt ccatatatag caggtttctt
    12001 tgtaagtata ccatgtgata atccaaaaga agtatgtgaa gaattgacta aacataattt
    12061 atttgcagtt ccattaaaaa tgggcttaag atttgcagtt tgtgcagttt ctgaagataa
    12121 atgtaagaaa gcaccaagta ttataaaaga agcacttgaa agtttagaag taaaaataaa
    12181 taattaattt cattgaacaa attgggtgga ctatgaattt aataattgta gatggaggga
    12241 attttatatg aaacaattga tgacaggtaa tgaagcaatt gcacgtggag cctatgaggc
    12301 tggtgttaaa tatgcatctg catatccagg gactccaagt acagaaatat tagaaaatat
    12361 agcaacatat aaagatgcaa tagttgcaga gtgggctcca aacgaaaagg tagcacttga
    12421 ggctgctata gggggttcaa ttgcaggagc aagaacaatg gcttctatga aacatgttgg
    12481 tttgaatgtt gcagctgatc caatatttac ttatgcatat acaggggtaa atggtggtat
    12541 ggtacttatt acagcagatg agccgggaat gcattcatct caaaatgagc aagacaatag
    12601 gatgtatgca aaatttgcaa agataccttt atttgaacca tcaactagtc aagaagctaa
    12661 agatatgata aaagaagctt ttgaagttag tgaaaaatac gatacaccag ttttatatag
    12721 agttacaaca agactttgtc attcaaaagg attagtggag tgctatgata gagaagaagt
    12781 tgaaattaaa gagtatgtta aaaatgctaa gaaaatggta actgttccag caaatgctca
    12841 aataagaagg ggcgttgttg aagaaagaat ggaaattctt aaaaaattct caaatgaaac
    12901 tgatttaaac tactatgaaa taaatgatac aaaaataggt gttatagcat ctggtatgtg
    12961 ttgtaatttt gccaaagaag tttttggaaa aaatgcatca tatatgaaac taggatttac
    13021 aaatccatta ccttatgaaa aaataaaaga atttgcagaa aaagttgata aaatatatgt
    13081 tatagaagaa aatgacccat ttatagaaga acaaataaaa gcatatggaa tagattgtat
    13141 tggaaaagat gtaataccac catatggaga aatgacacca gatgttttaa gaaaagctat
    13201 atttggaaaa acaaatgata ctatagaata caaatctgaa ttagtaacac caagaccacc
    13261 aagtttctgt gcaggatgtc cacatagagg attcttctat gaacttggaa agagaaaaaa
    13321 tttaatagtt ggtggagata taggttgtta tactcttgga tttgctcctc catataatgg
    13381 aatagattat gttgtttgta tgggttctgc ttttggaact gcacatggag ctcaaaaagt
    13441 tcttaatatg aaggatgata atgaaaaaag attggtaggt gtacttggag actcaacatt
    13501 cttccataca ggaataaatg gacttttaga tgttgtttac aatagaggta attctatttc
    13561 ggttatatta gataatagaa taactggaat gacaggtcac caagaaaacc caggttcagg
    13621 atatacttta caaggtgcta aaactaaaga agttgatata gaaggattag ttaaagcttg
    13681 tggaatagaa catgtaagag ttataaaccc taataattta aaagaagtaa atgaagcact
    13741 agattgggct ttagctatag aagatgaacc atcagtaata ataacaagat ggccatgtgt
    13801 acttaaaaaa ttctctaaag aagatataga agaatttaat aatccattta agactaagtg
    13861 taaagttgac catgataaat gtataggatg taaattatgt ttgaaaactg gatgtccagc
    13921 tctatcattt gataaagaga ataagttatc aaatatagat agaaatcagt gtgtaggatg
    13981 tggagtatgt gcacaagttt gtccaaaaca agcaatagtt aaggaggaaa aataatatga
    14041 ctaagagtat acttttggta ggtgtaggag gtcaaggaac tatacttgct agtaaattat
    14101 taactatggg attgatggaa gctggatatg atgtaaagat gagtgaaata catggaatga
    14161 gtcaaagagg aggttcagtt tcctcacaag ttagatatgg agattgtgtt cattctccag
    14221 ttatagaaat tggtggagca gatatattag tatcttttga aaaaatggaa gctttaagat
    14281 ggttcaatta tttaaaacca gaaggaaaag ctttagtgaa taatcatagg atagattcta
    14341 tgactgtttt aatcggagga gctgaatatc aagaaagtga tatagatgca gagttaagta
    14401 gattaaatgc aaaagttata aatgcagctg ataaagctga agaactagga aattcaaaaa
    14461 taatgaatgt tattttatta ggatgtctag ttaaatctat gcaattagag tctattgatt
    14521 gggaaaaaat tataagtgaa aatgttaaac caaaatttgt tgaattaaac ataaaagctt
    14581 tccatgaagg tatggaaatg gttagcaaat agtttataat agatataaat agactataga
    14641 aattaaggtg aaaggaagaa aattatgact tacagaatat tagccataaa tccaggttct
    14701 acttctacaa aaatagcagt atatgatgga gaagaacaaa ttcttgtgaa gacgatagac
    14761 catccagctg aagagattgc aaaatataat actatacaag accagtttga aatgcgtaag
    14821 gaagcagttt tgaatattct taaagaaaat agtatagact taaaatctct tagtgcaata
    14881 gtaggaagag gtggagtttt accaccagta aaatcaggag catatttagt aaatgaagaa
    14941 atgattgatg tactaagaca tagaccagta cttgaacacg cttccaattt aggtgctgtt
    15001 gtggcacatg caatatcaga acctcttgga atcaactcat atatttatga ttctgttgca
    15061 gtagatgagc ttatagatgt agcgagaata tctggacttt gtggaatgga tagatcaagt
    15121 gcagggcatg cattaaatac tagagcaatg gctttaaaat atgctaagga taaaggaaaa
    15181 gattataaga gcttaaactt aatagtagct cacattggtg gaggagtaag tatttatctt
    15241 catgaaaaag gaagaatggt tgatatgcta tctgatgatg aaggaccatt ttctccagaa
    15301 aggtcaggaa gagtacctgc tacaaaatta gtggctgcct gttattcagg tcaatattca
    15361 gaaagagaaa tgactaaaaa gataagaggt aaaggtggta tagtttcata cctaaatact
    15421 gtagatgcta gagaagttga aaaaatgata gcagaaggaa atgaagaagc aaaaattatt
    15481 tatgaagcaa tggcttatca gttagcaaaa ggtattggag agttagcaac tgtagtagat
    15541 ggaaaggtag atgctataat tataacaggt ggaattgcat attctgaaat gtttacttca
    15601 atggttaaaa agaaagttga gtttatagca ccagtagaaa ttatggcagg agaaaatgag
    15661 ttggaatcac ttgcttttgg aactttaaga gtactaaatg gagaagaaga agctagaatt
    15721 tatagtgaaa attaataaga aaaactaaaa atgtttatat actaaaaaag tggtatatcc
    15781 gttttttata cacgaaagct tagagtatag gtgaaaatgt ataaaatttg gattgccact
    15841 ttttataatt aaaattttat cttaacctaa taaataattc tgtaaaattt cgtatttata
    15901 tatatatttt attggtattt attgttatta ttattatgag gagtgatttt tgatgggaaa
    15961 aataagttta aaaagtatga taagattatt ttcaggtttt tttatatttg caatttcttc
    16021 tgtgcttatg attaatgcac atgtaggtct tatgccttgg gatgtacttc accaaggttt
    16081 atctataaag ctaggcataa ctataggtca ggcttctata atggtaggag ttgtaattgt
    16141 tatattggat gcagtttttg gtgaaaatat aggatggggt actttactca acatgacatt
    16201 tataggaatt tttattgatt tagtaatatt ttctggagtg atacctcatg caagcaacac
    16261 ttatataggt gtgtttatgg ttgttatagg aattattttg gcagctatag caagttttct
    16321 atacttaggt gtttgtttag gaagtggacc gagagatggg cttatgattg ctcttcagaa
    16381 aaaaactaat aaatctgtac gtcttgttag aacaattctt gaaatactag cattagttgt
    16441 tgggtggtta ttaggaggtt ctgtaggtat tggtacgctt gtaagtgctt taggtttagg
    16501 atatgtatta caaatagtgt ttagaatatt taaatttgac acaaaattgt tgaaacatag
    16561 atttattata gatgatataa gagaatggaa ggaaaagaaa agcaatgaac ataaatgtaa
    16621 atcaagtatt gtaataaaaa atgagcagaa ttaattatgc taaaatatat ttgtagttta
    16681 tctaatttat agtaaagtca aggagatttt gaaatggaat tatgggattt atataatgct
    16741 gatggaatta aaacaggaaa tgttataaaa agaggtaatt ctattgaaga aggttattac
    16801 catttggcag ttgaagtgtg gattttaaat agtaactctc aaattttaat tcagaaaagg
    16861 tctaaaagta aaaagacatt gccaaatatg tggggaatga caactggatg tattgtttct
    16921 ggggaagaca gtttagaagg agcaattcgc gaagcaaagg aagaaatagg gatagatata
    16981 actaaagatg agatgaaagt ttttagaagt atgattcatg aagatactct ttgggatgta
    17041 tacttagtta aaaaagaata tgatatatcc aaagctattt tacaggagga agaagtaagt
    17101 gatataaagt gggtaagcac agatgaaata agacaattac taaaagaggg tttgtttttt
    17161 gaatatccag agatatacga attgctatat gagatagata ataataaatt aaatatatga
    17221 tgtagagcag atttcagtat aagtaagatt atttaaaatg tatcttctct aaattttaat
    17281 attgttttat gaaaattaat aagttatttt tagtattttt ctacttgttt tttgagatta
    17341 aaataaaaag ggcagtcatt ataaagtcat aaaaatttgg ggaggattta aactatggaa
    17401 gataacaaag gattggcacg tgacagttca aaatataaaa ttgtttctat atctgtcgta
    17461 gtaattattc taattacatt ttggtatatg ttaaatatgg tgcttttaac atttattatg
    17521 acttttattt tctataactt gcttgtagcc acaagaaaac gaattaagaa gttttcttct
    17581 ttaaatattc cagattcatt aataattata gtgttatatg cactatttgc tatattgtta
    17641 gtattgatta gctatgcagt tgtaccaata attatagttc aacttacaga gttgagtagg
    17701 gtttttagtg attttgatgt aaatcaattt gctcaatctt taggaccaaa attgtatcct
    17761 attgtctcaa agctggattt taataaatat atttcacaag cagggctact tatagcatca
    17821 acagcaacaa aagttggaag ttttggagta aatatattat tggcattttt actgagttta
    17881 ctccttttac ttgaaaaaaa tgaaattaaa aattttggag ataaactttc tgatagtaag
    17941 atttctttta tttataattc gcttgtattt tttggaaaga gctttgttaa aaattttggt
    18001 gaagtaatga aagtacaagt tatgattgcc tttataaatt ctgttgtttc tatgattttc
    18061 ttaggtttca tgggattccc tcaaatatgg gctttaggat ttatgatttt tgtgttgggt
    18121 cttattccag tagcaggagt tatagtgtct ttgattccat taactgtaat agcatttaat
    18181 acaggaggaa taacaaaggt ttttggagtt ttacttatga tttgtatagt gcatgcagta
    18241 gaaacataca tattaaaccc taagttgatg tcgaatagaa ctaaacttcc agtttgtttt
    18301 gtttttatta ttttacttgt aggagaacat tatttaggtg tatggggatt actaattgga
    18361 gttccaatat ttatgttcct tatggatatt ctgggtgtta aatttacttc taggtaatat
    18421 attaaaataa taatttatct ttatatataa attataaatt gttttaaaaa agaacctata
    18481 aatagacatc attaataaag acatctattt gataggttca attttgcttt gtataaatac
    18541 tataaaacta aataaaaaga aatttatttc atttcaaaag tttcacaact tgcatttctt
    18601 tcatttatat gaactttttc agctttgcaa agttcatttt tattgtattt acattttaca
    18661 gcttcacaat gaatgttatc tgtatcaact tggttagttt cattagaacg actagttata
    18721 ccagatgtat atttgtcttc aaaagaagca caataagtat tttctgtagt agttgcttgc
    18781 attccatcta cttttatact accagcataa caatatccac tagtattata agcacaatta
    18841 gtagcagcac aatttaaatt attatttttc ataaataacc tcctaagttt tatttaaact
    18901 tattatgtga agttatctaa attttataca cttatttaca attacattta tcacatttaa
    18961 caactacatc tttggaagtt tcccttccta aatttttatt aacatgatac acatcaacat
    19021 tttcagttga tccacatata gaacatttaa aattgttttc tagtagggtt ctttctttaa
    19081 ataacttcca atacatagaa ttgatgtaat cattataatt taccttgagg catgtctcaa
    19141 gaaagtttat gtatagattg tctaaatctc ctgtatttaa ttctgtatat tctggttcaa
    19201 aatattcaca acatcctcta aaatcgggct ttgtatctga aataacacat ctaatatcat
    19261 atctatagtc taggctaggc cccttaaatg aaagatgtgt gcaaaaagaa caagatgttt
    19321 ctggtagatt tttttcaagt tcatgtaatt tattattcat aagtattcct ccaaaaaatt
    19381 tattttaagt atataaacga atagattatt ttaaaacttt tatttattta tattagagat
    19441 ttaggataaa tattccaata aggagtaaat acttaagtat ttattactgt attaaataaa
    19501 aaagaggcaa atctaacttg agattgccta cttttttatc attttttaat aaaatttatt
    19561 ctaagtatta ttttatttag atttagtcag ccaacttagt atctgctttg ctttttaact
    19621 ttctaccaga gcgtacagtt aaaatagcat ataatacagt aaatatggca gctaaaacat
    19681 atgatatatt tatgtttaag ttaaatccaa tttgagcatt aaatatataa ctgaatataa
    19741 caaaggaata aaacatacca ggaattaagc ttataatata attcttttct tttattataa
    19801 ggtaaactgt aatcattgca aatgcaaata tggcaatagt ttgattactc caagagaagt
    19861 atctccacaa tatattaaat ccagaagcac taagctttgc aaatataagg atggctatga
    19921 caggaataaa tatacagatt gacaatataa cacgatgttt tttttccttt tggtcataat
    19981 gaaagtaatc tgcaagcatt aatcttaaag atcttaaagc tgtatctcca gaagttattg
    20041 gtaaaacaat tacacctatt atagctatga taccaccaat agaaccaagt aaatctcttg
    20101 caaccaaacc tattacatca ggagaaccta ctaattcctt aggtattcct ttattgtaaa
    20161 tacccatagc agctgcagcc caaatcattg caattaaacc ttctaaaatc atcatattat
    20221 aaaaagtagt ttttccttct ttttcatttg aaactgatct tgctataaga gtagcttgag
    20281 ttgagtggaa tccagaaaca ataccacaag caactgtaac aaagaatgta ggaataagag
    20341 gaataccatc aggatgaata cctttccaat ttgcaagact taaattagct aaatcataac
    20401 cttgtgtaaa gattccaatt ccaacaccag cagcagataa aagtagaata gctccaaata
    20461 ttggatatac ctttcctatg attttatcaa ttggaaatag tgttgcacac aagtaatata
    20521 gaaagataag tccataaact atccagacaa ctggattatt tatagtcgat ttcatattta
    20581 aaatttgagt aacaactaaa tccccaggtg tataaataaa aactgcacca actaaaagca
    20641 ttaaaagaca aaggaatata ttatagactt gaaatacttt attacctaaa aatctactga
    20701 taagagaagg catttgtgct cctttttctc ttatactaat cattccactc atatagtcat
    20761 gcaaagctcc tccaaataca cagccaatag gtattagtat gaatgctatt ggaccaaaca
    20821 atataccttg gataggtcct agaattggtc ctgtaccagc tatattaagc aactcaatta
    20881 gactattttt ccattttttc attgggacat agtctactcc atcactttga gcaagtgcag
    20941 gtgtttttct gtcatctggg ccaaatactt tttcacaata agcaccgtat aaagcacctc
    21001 ctattagtaa tatagccaag ccgattaaga atgttgtcat aatatcaccc catttataaa
    21061 attttttggt ctttgtatac atattatcta aatgtgtaga tttatattga atttaattct
    21121 ggacaaccta caaattctat aaagtattac aactaatata atttcagaaa taaatacata
    21181 tacataacca tgtacttagt atacaggtat ttggtaatat tttcaatgtt atagcaataa
    21241 agaatataga caaaattctg ataatatttt acaaaaaaat taaaaaatat aaaaattagt
    21301 ttaaatagat ggagaaaaaa ggaaaatcaa ttgagaatat aaatgtctat atcttaacaa
    21361 tattaagagg tttaaaattc ttgaagaaag aatagtcaag tgatataatg agtttacagg
    21421 tgtatataca ctagtacata tagaaagcgg tgcaattatg gataaagatt taacatatca
    21481 aatcaaagag ctaaagaaag aaaaaaatgc aataatactt gcccattttt atcaaccacc
    21541 agaaatacaa gaattagcag atgcagttgg tgactcatat tatttaagtg agattgctag
    21601 agattgtaaa gaagaagtgg ttgtattttg tggagtaagg tttatgggag aaagtgctaa
    21661 gatattatca cctgaaaaaa ctgtattgat gccagtaagt aacgctgggt gtgctatggc
    21721 agatatggta gatgaagaag gcgtgataaa attaaaacaa cagtatccaa atgctttggt
    21781 tgtatgttat ataaactcta cagctaaagt taaggcacat tgtgatgttt ctgttacatc
    21841 ttctagtgca attaaaatac tagaaaacat agataataaa gaaattatat tccttccaga
    21901 taaaaattta ggaggatata ttgcagaaca atttccagat aaaaacttta tattttggga
    21961 cggatattgt aaataccata acaatataag agctgaagaa ataattgagt taaaagataa
    22021 gtataaaaat gcagaagtat tagtacatcc agaatgtaaa aaagaaataa gagatttagg
    22081 agattatgta ggtagtacat caggaataat aaaatatgct actaatagta aaaacaaaga
    22141 ctttataata gcaactgaag aaggtatatt acatgaatta aagaaaaata atcctaataa
    22201 aaacttttat attcctggtg gaaaaatact atgtacagat atgaaaaaga caacattaga
    22261 aaatttatat agtacactta aaaatatgga aaatgaagtt attgtagaag atgaaatcat
    22321 ggaaaaggct ttaaattcac tgcttaacat gcacaaatta gcagaaggat agagggatag
    22381 acttatgaat ttagaacaag atgttttaat agttggaagt ggagtttcag gattatactg
    22441 tgcattaaat ttagataaaa gtttaaatgt gctagtagta tcgaaatcaa caattgaaaa
    22501 caacaataca tatcttgcac aaggtggaat ttcaactgct agaaatattg atgatataga
    22561 atcctttgta gaagatacaa tgaaggctgg gcagtataaa aatagagttg aagcagttca
    22621 agtacttgca gatgaatcta tagaaaatgt agggcagata gtagaatatg gtatgccttt
    22681 agacaaagaa aatggagaga tagattacac aagagaagga gcacatagtg taaatcgaat
    22741 agttcatagt aaggataata ctggagaagt tgtttttaaa actttattaa aagaagctaa
    22801 aactagagaa aatataactc ttatagaaga tgcctatctt ttagatatat taaaagatgg
    22861 caataaatgt ataggagcta gaatttttaa atctaaaaaa gagattcatg ttttttcaaa
    22921 aatagtagtt ttagctacag gtggaattgg tgggcttttt aaaaattcta ctaatcaaag
    22981 acatcttaca ggtgatggaa ttgcaatagc tttaagaaat aatataaaaa tagaaaattt
    23041 agaatatatt caaatacatc ctacagcctt ttatgaagaa aataatgaag gtaggagaat
    23101 gcttatatct gaatcattaa gaggagaggg agctaaactt ttaaataaaa ataaagaaag
    23161 atttgtggat gaacttcttc ctagagatgt agtttcaaaa gctatttttg agcaaatgga
    23221 aaaagataaa ttaccttatg tgtatttaga tgcaacacat ttagatagtg aatatttaat
    23281 taatagattt tcttttattt ataatgaatg tttagctaga ggaacagaca taacgaaaga
    23341 atgtataaag gtatctcctg cacaacatta ttttatgggc gggatacatg tagatttgga
    23401 ttcaaaaaca tctatggaaa atttatatgc agttggtgaa attagttgta caggtgttca
    23461 tggagccaat agattggcaa gtaattcatt acttgaaggg cttgtatttt caaaaagagc
    23521 agctaaaaat ataaactcag ttatagataa tgtaaaagtt aagtttatag atgtaccaga
    23581 tatggatata gatatagaac aggtaaaaaa agaaaataaa atattagtca taaaagaaat
    23641 tgaaagaaca agtgaggatt ttggcgatga attatttgat tattgataga atgatacagg
    23701 atgctttgat agaagatgtt ccaagtgaag atataacaac taattctatt gtggatgaaa
    23761 attctaaatc tactgtagat ttaatttgta aacaagatgg tataatagct ggcttaggtg
    23821 tatttaagag agtttttgag atacttggtg atgtagatgt aaaattatat aaaaatgatg
    23881 gtgatagagt aaagaatcgt gaaaagatag ctgtattaac aggtagtact agaaacttac
    23941 ttgtaggaga gcgtgtagca ttgaattatt tacagagaat gagtggtata gctactatta
    24001 caagtaggta tgttgaaaag cttgaaggta caaatacaaa attattagat agtagaaaaa
    24061 cgatacctaa tcttagaata ttagataagt attctgttaa agtaggtgga ggatgcaatc
    24121 atagatttaa tttatctgat ggaatattgc ttaaagacaa ccatattggg gctgctggta
    24181 gtgttaagaa ggcagttgaa ttagctagaa aaaatacttc ttttgttaga aagatagaag
    24241 tggaagtgga aactttagac atggtaaaag aagcaataga agctaatgca gatataataa
    24301 tgttggataa tatgagtttg gaaatggcaa aacaagcagt agatattata aatggaagag
    24361 ccattgtaga attttccgga aatgtaaatt tagatactat agaagatata ggaaaaattg
    24421 gtgtggatgt tgtttctgta ggagcgctta cacattctgt taaagctctc gatataagta
    24481 tgaagaattt gagaaatata taaattttat attgaaataa acttaattaa aatagactcc
    24541 ttaaatttgt tttataaatt taaggagtct attttttatt cattaaaatt aataaaaata
    24601 gaaaaaaatc aatcaataat ttaataaaaa tagataaata ctatatacac ttttaataat
    24661 atagttaata tctattttac agataaataa gaataaactt ataatataat tgtatctgta
    24721 aaattttgta aaatataaaa agtatagggg gaataaaaat gaaagtagct tatattttta
    24781 gtagtactaa tacacataaa attctagaca aaatgataat accacaactt gaacaaggaa
    24841 ctcatggagt agacgttcta gggatgtttt tctttatgga taatacctta tttttatcta
    24901 aaggtaatcc tgtaggcgag agactaagta aattacatga aaaaactgat atgataataa
    24961 tggcttgtga ccaatgtgct atagaaagag gtatagagaa taatttggtt gatggagcta
    25021 caattggatg tttcccaaac ctatatgctt gtttaggcag tgcaggtgtg gaccaagtta
    25081 taacgttata aattagtata ggatacaatc catagaaaaa tttattttct gtggattatt
    25141 ttaagtaaaa gataaattgt ttaaagtagg ggattaacaa atgtctaaaa ttttagttga
    25201 atttataaac acttgaccat cttgtgatga acatggagtg tttataaaaa aaatgtcaga
    25261 aaaatatgct gataaattgg aaataaaatt atatcaagca gggaaagatt tttcgtatat
    25321 aaaaaaatat gggattataa caaaaggaac tttaataata aatcagaaaa agaaatatga
    25381 tagattaaat aaagatacaa ttgaaagggc aatagtagaa gctataaaca ataattaaaa
    25441 gtttaaaaat taggagtatc aaaaatgaat atattagaaa ttgttttaaa tggagttaaa
    25501 gatactatag tagcttctat agttacactg aatggagcat caggatggct tatgataagt
    25561 tttatattgg caggtgtact tcacaatgtt ttaactccaa gaaggtttca aaaacaactt
    25621 ggaaataaga aattttcttc tttaattaaa agtactatct caggaatgtt tttaccaata
    25681 tgtagttgtg gagtaatacc acttggaata agtatgtatt attcaggagc atatttagga
    25741 ccagtacttg cttttatgac atcaactcca ataataaatc caatagctgt agttctttgt
    25801 ctaggtcttt taggtcctaa agttacaatc atttatctaa tagctggttt tttagtacca
    25861 tttttagtag gatttttagg aaattgtttt ggaaaagaag aattatcact tcataatgat
    25921 tcagaggaag aagtaataga attagaagaa gaaaaaagaa gttttatggg aaatatgatt
    25981 gatggtctta aatggtcttt tggtgaatta gcccttacta ttagtaaata tgtagtaatg
    26041 ggtatggttt ttgcaggatt tataacaact atttttccaa atagtataat tcaaaaatat
    26101 ttaggaaatc caggtttgct atctcttgga agtatagcaa tacttgcatg tgttatgtat
    26161 gtatgtgctg taggacatat accgtttata gcagcccttg ttgcaagtgg agcatctcct
    26221 ggtatagcga taacatttct aatagctgga gcagctacaa atctaccaga acttataagt
    26281 atgtttaaac ttattggaaa aagaactgtt attatatatt ctgtaacttt gacactgtct
    26341 tcaataataa ttggatatat aacaaattta cttttagtga ataataactc agtaaattta
    26401 gatgcaacaa attcttcaat acagttggca aataaactaa tgttaaatat acctgatagt
    26461 tttgagtatg tatgtactat tttaattatt ttatttgcat ttaaatcaat aataccaaag
    26521 atgaaagagg tcataggaaa tcatgcttaa aaagatagtt ataatatcct gtatagtagt
    26581 tgtgttaatc attttatcaa aaatagttga tgataacatc aaagaagatg cttctattcc
    26641 aaatgtgaat aaagaaacat tagaatattt tagaaaaaat tataaagaag acataataac
    26701 ttgtgctgaa gaagacttaa ataatgatgg aaaaaaagat ttagtagtta tatataaaaa
    26761 aagcaataat tcaaatgaaa tggtagtcgt agtttctgat aaaaatagcc actatataac
    26821 aaagccaata ccagcaccta tagagaatca aacgataacc tttaaaaata ttgatgataa
    26881 agcaccaata gaagtaattg tatcagggtc taaaaatggt aatgtaggat atgctattta
    26941 cagagtagag ggtaaaaaat ttgttgattt atttggcgaa gatatggaca aatgttgcta
    27001 aaaataaaaa taatacataa aggtgggaaa tttatatgaa attatctaag aagattcaag
    27061 cattaatctt atttggtgta atgggtacat ctatattaac aggatgtagt agtaaaccaa
    27121 aagaaaaaga agaagcaaaa actggaaaag atgattatac aataacagta ggttattata
    27181 attgtgacca tatgactgcg ggaccagtag cagaatcggc aggaatatat aaagatttag
    27241 gtcttaatgt aaaaactgtt ggaaatggta aagttcctga agctatggca gcaggaaaaa
    27301 tggatgcagg ttacatagga actaaggggt tagttggagc aatacctaag ggttcgccaa
    27361 taacaatagc agctaacaac catactggtg gttctgaata tttaatagtt tcaaaagata
    27421 taaaagaacc taaagattta ataggtaaaa aaattgcaac agatatgagt gatttcttat
    27481 ggacaagtga ttatggtcca gaaacaggtc taccaactga cccatcaaaa tatgaagttg
    27541 taaatatgga ttcagacaaa gataaatatt tagctcttaa aactgggaaa attcaagctt
    27601 ttacatcttg tgacccttgg ggttctgtag ctgaaaatga cggtgcagga aaaataatag
    27661 catctactca atataaagaa aaagctaatg gcaaagaata taactgttgt tcattctcat
    27721 taaacaaaaa ctttataaaa gaacatccag atttagcaaa aaaattggtt ctagcacata
    27781 caaaagcaat agaatatata tatacaaatc cagctgaagc agctaaaata tttgcaaaat
    27841 attataatgt agaagaagaa gttgcactta gaactatcta taagaagact gttggagaag
    27901 gtagaactct tacttggaaa gttacaggtg aagaatataa aaataattta caaatgtata
    27961 aagatttaaa ggctttagat gatataccta aatatgaaga tacgattgat acaagcttat
    28021 tggactcttg tggagctgat gattttgaca aatttataaa agaaaaagtt aacccagagt
    28081 ttcctgaagg tatgagttat gaagactgga aagcaaaggt attataaata aatggagaat
    28141 atgaaaaata taataatact ttttatcatt attttgggaa gtatatttat aatatttttt
    28201 aattttgaag ataaagaaga aataaaagga aaattaagaa taggggtatc tgatgatacc
    28261 tctggttttg taataaatta tatggtaaat agagactact ttgaaaatat aaaagtaagt
    28321 gatataatgg atatttttac aattaatgat tgctgagcaa gtacaatgca gtgggctctg
    28381 agttcagagg aaatagatat agcaatcata tgtaaagatg ctgcaaaaca atatgtaaat
    28441 gtaaatagtg gatttgaaat tgttggtact gtagttcaaa attctgatat atttctatta
    28501 agtgataata atcctgaaaa gataggagtc attcaaaata gagattacca gtcagaattg
    28561 gttaaaaaat actacaagaa tgtggaagta gctcccttat tagggactgc actagcatat
    28621 ggattagaaa gtaatttagt agatggtgtt gtaatagatt gcataaagtc aattgggtta
    28681 gagggtaaaa gaaaatctac aactaaatta ggagattatg atacctatgt attagttgta
    28741 aataaagagt ttaaaaaaag taaagcatat agtgatttta taacacttta caataaaagt
    28801 gttgatgctt taaagaataa agctacattt aagaaagtat taaaagagta caggaatata
    28861 agaaatatag atatggagga aataagcaat tggaaattaa aatttctaaa gataaaagcg
    28921 atagattaac taagaaaaaa actgatggta gtatggatat tttatataaa ataatactat
    28981 tagttattat atttttagtc tggcattttg cagcaaaaga tatagggagt tctttgttac
    29041 ttccaatgcc agtagatgta ataaaaggtt tctttttctg tgtgacagat gcagagacag
    29101 tcactaatct ttttataaca ttgcagagag tacttaaagg ttttatgtat gcattattgt
    29161 ttgggcttcc aataggattt attatgggat tttctaaaac ttttgaaagg gttttatctc
    29221 cagtagtaga ttctgtaagg caagttccaa taatggcatg ggttcctctt actatagtat
    29281 ggtttggtat aggagatggt ccaacaatat ttttaatagc tttttcaggg gttttcccta
    29341 taattttaaa tactattcaa ggagtaagag caatatcaaa ggattattat aatgcagcta
    29401 gaagtatggg agcatcgcca attgtgatat ttacaaatgt aattgttccc gcatctcttc
    29461 cagatatact aactggttca aggattgcta taagtacagg atggatgtct gttatctgag
    29521 ccgagtttat agctacgagt gccggtctcg gttactcaat ggtacaagct caaacattaa
    29581 tgcatacaga tgtattaatt gggcttatga tatttgcagc tttaatagga tttataatag
    29641 atagggtatt aaagtttata aataaaatcc tttgtagatg gaggtttgca gattaatgaa
    29701 gttaagtgta agagatataa ataagacatt tgtaaataat agagtacata caaaggtttt
    29761 agaagatata agtatggata tagatgatgg acaatttgtc tgtcttttag gaccatcagg
    29821 ttgtggaaaa acaactttac ttactataat aggtgggttt caaaaatcag aacgtggaga
    29881 tgtttttata aatgataaaa gagttaaaaa accgggcata gatagagctt ttatatttca
    29941 aaattatgct ttatttcctt ggaaaactat aagaggtaat gttctatttc ctatgaaaca
    30001 gcagaaaata ccaaaagaaa aaagagaaga aatgctagaa gaacttttgg ttatgtcaga
    30061 cttgaaagga aaagaaaaac tgtttccgca tcaattatct ggaggaatga aacaaagagt
    30121 ggccatgata agagctttag catgtaatcc agaggtatta ctaatggatg aaccattagg
    30181 agctgtagat tttcaaatga gacaaaattt acaggaagag ctagaacgaa tatggataaa
    30241 gaagaaaata actgcattaa tggtaactca tgatgttgat gaagctgtat atatgagtga
    30301 tagagttata gtaatgtcga gagataaagg aagaattatt gatgatataa atatagatat
    30361 tccaagacct agaattagag gaagccaaaa atatgaagag tacaaaaaca aattaactga
    30421 tactttatca aagtgttatg aagtttaaag aggagtagac atgagtcaaa tagaaaaata
    30481 caatagtttg gataatacac aacagaaaat aagaatctct attatggata tgataataga
    30541 taaaggttct agtgttacac ttcaagaagt gactgaatat gtaagtaaaa agttgaatat
    30601 agaaaaagaa tatatagaaa ggacactaca atattttatt tataaaaata taatggttgt
    30661 tgatgggaat agtataaatt ttatatatcc tgtatcagca ttgccaacaa atcataaagt
    30721 aactttgaga gataatagaa gtttcagtgc aatgtgtgct atagatgcta taggaacctc
    30781 ttgcacattc aaccaagata taaaaataaa ctctatttgt agtgctacag gtaaggaaat
    30841 agaagtaatt ataaaaaatg aaaagattga gtatgtgaat aatccaaact taagagtgct
    30901 tcatataaat cttgataagc atctaaattg ggctgctagt tgctgaaata taatgaattt
    30961 cttctggacg aagagtgatt ttgatgcttg gacaaacgaa gcgggattat ctgatgatga
    31021 agatatatat tgtttagata ttaatgaggc aatagtagaa tcatataaaa tatttaaact
    31081 caaacaaaag gtactatcat agatatacat atatgaaaaa ctaaaaatga cctttagata
    31141 aaaatgatag gtaatatcca tactatataa attagtatag agtagggatg tgaaaagtat
    31201 ttaaatctaa aggtatattt ttagtttttt tagatgatta gatagcctta ttaagtatat
    31261 atttatttat aacctttgca actccatttt cattattagt atcagtaaca taatctgcaa
    31321 tttcctttat actattacgt gcattcccca tagccacacc aagacctgca tactttatca
    31381 tatgttggtc attttcttca tcgccaacag caatagcatt ttctataggt atatttagat
    31441 tcgtacataa tgttttaaga gcagttcctt tattagtagt tttacctaaa aattctagat
    31501 aaaaaggagc agaccttact atagtatatt tattgaataa atttttaggt agttgctgta
    31561 tgatttcttc caatctttct ggttcatcaa ctatcataat tttacagatt ttaatagatt
    31621 catcaatttt atctttttgt atatatttga cttctatatt atttaatttc gcttcatgaa
    31681 gtgtatattt gccaggcgtt tcatttggtg taattaaatt tgtcattgta tttatgtgta
    31741 ttttagtctt atatttttta caaacgttat tatatataaa atcaaaatca tctaaactca
    31801 tttctacatc atgtatgatt ttctcacttt taacttcttg aataattgct ccattaaagc
    31861 atataacata atcaccttca tctgttaaat ttagttgatt tagaagttct tttacaccag
    31921 gaagaggtct gcctgttgtt ataactactt ttgccccagc cctttttgcc tcctgaatgg
    31981 actcaaagac ttcaggagta atcctttttt gtgtatttaa tattgttcca tcaatgtcta
    32041 gtgcgattaa tttgtacata tcaacctcca ataaattata tactcaaatt tcctgtgaaa
    32101 acgttgacac agctagtgtt gaacaaagtt tcagtgggaa atatggtttg ttttgtatac
    32161 tattatatca agagataagt aatttagaaa gtttaataat attaattttt tgataaaaat
    32221 attacttatg tgagatgaga atgtaaaaac tttgtaatca ataattccaa aattcttaat
    32281 tacaaataat ggtatcgttt gcattgttaa tataaataaa tgtatattat atagttagaa
    32341 gtttgaataa atagactgat ggtaatttgt tatattagtt agttttgtgt tataaaatat
    32401 tgtaattcca ttaatcatat gttattattc aacatgatta taatataaag aatatttgat
    32461 atatataata atttataaaa gagtattaca tagtacatat aaatctatat ttataaatac
    32521 aataaagtaa agttgtaaag gagtgcttta aatgaagttt tcagagttta agtatgaaag
    32581 acccaattat aatagtatga aaaaagagtt tttgagttgt gtagaagata taaataattc
    32641 tcgtaattat aaagagcaac aaaaaaatat acataagatt aatttattaa gaaataaaat
    32701 agaaacgttg tcaaatatag cttcgataag atatagtaca gacacattta ataaattcta
    32761 caaagaagaa aaaaattatt gggatgaata tatgcctttg tatgaagaat taaattcata
    32821 tttttataat gccattgtaa attcaaaatt taaatatgat ttgataaaag agtttggaga
    32881 gcaatttttc acaatagtag agtattcttt aaaaagtttt tccaaagaaa taataagtga
    32941 attgcaggaa gaaaataaat tgtgttcaga gtatactaga cttttagctt cagctgagat
    33001 aatgtttgat gggaaaataa gaaatttatc tggtatgggg aaattcatgt attctaagaa
    33061 tagaaaaaca agagaattag caaacaaagc atattataat ttctttgaag aaaatgaaac
    33121 taaatttgat gatatatttg ataaattggt taaacttaga gataagatgt ctaaaaaatt
    33181 aggttttgaa gattttgtag agcttgggta cattagaatg atgagaagtg actacagaga
    33241 atatatgata aaaaatgtta gaaaacaagt actaaaatat gttgttccaa tggcaaatga
    33301 gctttatgaa aaacaagcta aaagaattgg tctagaatat ttaagttaca tagatgaagg
    33361 cgtggaattt ttaacaggaa atgcaagttt aaagggagat tcaagataca taattaaaaa
    33421 tggtaaaagg atgtattctg aactgtcaaa agaaacaaat gaattttttg attttatgtt
    33481 agaaaatgaa cttatggatt tagaaacgaa gaaaggaaaa ggagctggag ggtattgtac
    33541 ttatatacca gattataagt caccattcat tttttctaat tttaatcaaa ctgctgatga
    33601 tatagatgta ttaacacatg aggcaggaca tgcatttcag ttgtatatgt ctagatggat
    33661 tgatatgcca gaaattaatt ttccaacgct tgatagttgt gaaatccatt caatgagtat
    33721 ggaatttata acatggccgt ggatggattt attttttaaa gaagatacag ataagtacaa
    33781 attcactcac ttatcatctt caattaaatt tataccttat ggagtaattg ttgatgaatt
    33841 tcaacactat atttacaaaa atcctaatgt agataagtca aaacgaaaag aaatctggag
    33901 atttttagag aaaaaatact tacctcatag aaaatatggt gataattctt ttttagagag
    33961 aggttgttgg tggtttaaac aaggacatat atttaaaaat ccgttttatt atatagatta
    34021 tgtattagct caaatttgtg cgttacaatt ttggaaaaaa atgattcaag atagagatgc
    34081 aggatggaaa gattatataa atatctgtaa agttggagga acaaaatcat ttttagatat
    34141 tgtgagtatg ggaaatttgt attctccatt tgatgatggc tgtattgagt ctattatagg
    34201 tgatgttaaa tcttggtttg atgaaataaa tgacagcaaa ttataaaaaa ttatgagaat
    34261 tttattgtat aaaagtaaaa aattaaaaaa tatataaaaa gtgattattt gttgtgaaaa
    34321 tagtcttgtt tttaactaaa ttgataaaat aaactaaaaa agatttgtac ttaaaaaaaa
    34381 aagaaaatac aagaaatatg caatatcaac atttggaaaa aaaagtaaaa atgtatacaa
    34441 aatacatata aaaaaactat tgcaaatttt atagaatgtt tatatactta agtcaacaga
    34501 gatagaaaaa agctatttat agaaaacaaa ggataaattg cttaatttta aattttctga
    34561 aaaaaataat aatccggatg aagagtatgg gagactgctt tataaaaagc gaccgaaggg
    34621 acaagtttaa tcttacttac ccaaaagatt agatgaaatt ctcaggtaaa ggtgactgta
    34681 cttggacggg gctctgaaaa tgattttaac agggaagaca aattgggaga tttgtttttc
    34741 ctgtttttta tttatcaagt aataaataaa agtttgaaag agagtaaaaa aatgataata
    34801 attacgaata atccaaaagt aaaagaagaa gttcaaggca gagaagtttt gtttaaagac
    34861 acaacttata ttggaatctt agaagcaagt agagatttga tacatgaagg ttatgaactt
    34921 ttatctcatc cactctatgg gagtgtaaag ccaaatgaaa caccttacag gactgttata
    34981 ctaaagaaag gaaatcgttt ggatataaac tctttaacct taattgaaga agcaatcatc
    35041 actgcaagta aatttcagaa taataaaaag actccaaaat ggacagaaag tgttcaagat
    35101 gattttagag taattgatta tgatatattt tataatacaa tacaaagaat gcagtatgaa
    35161 taaaaaaatt gttaaaaagt tattaaaaca gcctaaatat taaatctaat ttaatattaa
    35221 ataaaatgag aaatttaatt ggggaggata agtcaaaatg gaaaatgtgt atgacttagt
    35281 aataattggt tcaggaccag cagggcttgc agcaggtctt tatggagcaa gagcaaagtt
    35341 aaaaactcta atcctagaaa aagacaagac tggtggacaa attgtaataa cacatgaaat
    35401 tgcaaattat ccagggtcag ttccaaatgc aacaggacca agtttaatag ctagaatggt
    35461 tgaacagtgt aaagagtttg gagcagaaat gctaagagac aacattgttg atactgagct
    35521 agatggagat ataaaagttt taaaagggga aaaggcagaa tatagagcaa aagcagtaat
    35581 aataggaaca ggagcaacac caagaaagat tggttgtcct ggagaaaaag aacttactgg
    35641 taaaggggtt tcatattgtg caacttgtga tgcagatttc tttgaagatt ttgaagtatt
    35701 tgttgtaggt ggaggagaca gtgcattaga agaagcaatg tatttaacta aatttgctag
    35761 aaaagtaaca attgtacata gaagacaagg atttagatgt gctaagagtg ttgaagaaaa
    35821 agcaaaagct aatccaaaga tagagttttt attagataca gtaattgaag aaatcaaagg
    35881 tgatggaata ttagaatcag ttgtatttaa aaataaagtt actggagaaa ctcatgaata
    35941 ctttgcagat gaagaagatg gaacaatggg agtatttgtg ttcgttggat tagatgctca
    36001 aactgattta ttcaaaggta aagttgatat ggatgaaaaa ggttacataa taactgatga
    36061 agatatgaga actaacatac caggcgtatt tgcagcagga gattgtagat ctaagactct
    36121 aagacaggtt gtaactgcaa ctaatgatgg agcaattgca tctatagtag ctgagaaata
    36181 cattgatgaa aaatttggga actagaatct gtaaattaag aaatagtgtc tgtaaattta
    36241 atgaataata tttaaaatta aaattaatat ttaaaataaa aataaaaatt tcaaggggga
    36301 ataagaaaat gttagattta gataaggcta catttgaaga agaagtttta aatgcagaag
    36361 gttttgtatt tgttgatttt tggagtgaag gttgtgagcc ttgtaaagct ttaatgccag
    36421 atgttcataa attagctgag acttatgggg ataaaataaa attctgtaag atggatacaa
    36481 caaaagctag aagattagct ataaaacaaa aagtattagg tcttccaact atggctatat
    36541 acaaagatgg agaaaaagta gacgaagtta ctaaggatga tgctacagtt cctaatatag
    36601 aaaacatgat taaaaaatat ctttaatatg ttgataaatt attaacatta aaagaaaaaa
    36661 tctattttta tctgaagata agaagaaaaa ggtttttatg tccaactttg ttaaaaaaat
    36721 aattttaaat aaaataattt ttttacaata aatatttttt agtaataaaa taaagattta
    36781 aggcataaaa acacaataat atatctttaa aaaaataaga taaattgtaa aatgatataa
    36841 ttttgagaaa aactcaaatg catatacaca aattaaataa caggaggtgc aagtatgcgt
    36901 cttgaattag ggaaaatctt tataaaagat attcaatttg gtgatgtaac agaagtaaaa
    36961 gatggagtat tattcatcaa taagcaagag atgctacaag aaattggtgg agatgagcat
    37021 attaaatcta tagatataga attagctcgt ccaggtgaaa gcgtaagaat aacacctgta
    37081 aaagatgtta ttgagccaag agtaaaagtt gaaggtaatg ggggaatctt ccctggtatc
    37141 atgtctaaag ttgacactgt aggagaagga aaaactcatg ctttaaaagg tgtagctgtt
    37201 gtaactactg gaaaaatagt aggtttccaa gaaggtataa tagacatgac tggagaagga
    37261 gctaagtaca ctccattttc taaattaaat aatgtagtag taatagctga acctattgat
    37321 ggtttaaaac aatacgctca tgaaaaagct gttagaatga taggattcaa agcagcaatg
    37381 tacttaggag aagtagcaag aaatcttact ccagatgaag tttcagtata tgaaactaaa
    37441 cctcttcttg aatcaataaa agaatatcca gagcttccaa aagtaggata tgtttacatg
    37501 cttcagactc aaggtttatt acatgatact tatgtatatg gagtagatgc aaaacaaata
    37561 gtaccaactt tattatatcc aacagaatta atggacggag caattgtaag tggtaactgt
    37621 gtttctgcat gtgacaaaaa cccaagttat gttcatataa acaatggggt tgttgaagac
    37681 ttatatgcaa gacatggtaa agatataaac tttgtaggtg taattataac taatgaaaat
    37741 gtttatctag cagataaaga aagatcttca aactggactt ctaaattatg taaatattta
    37801 ggattagatg cagttatagt ttcacaagaa ggttttggaa atcctgatac tgaccttata
    37861 atgaactgta agaagataga aatgcaaggt gttaaaacag ttatagttac agatgaatat
    37921 gctggacgtg atggaggttc tcaatcactt gcagatgcag atgtaagagc tgatgctgtt
    37981 gtaacaggtg gaaatgccaa ccaagttgta gttcttccta agttagataa agttattgga
    38041 catttagaag tagtagatgt aatagctggt ggttctgatg gaagtttaag agctgatgga
    38101 actattgaag ttgaaatcca agctataaca ggtgcaacta atgaaacagg atttggtcat
    38161 ttaactgcta aaggatatta agaagtattt tattaaacga ttgagtaatg ttaataaaac
    38221 atattataga taattataat aagtgttata gatatataaa aatatattag aaatataata
    38281 aggaggatta ttatgagttt acttagtaat aaaaaggttc ttataatagg tgaccgtgat
    38341 ggtataccag gacctgcgat agaagaatgt gtaaaaacag tagaaggagc agaggttgtt
    38401 ttctcatcta cagaatgctt tgtctgaaca gctgctgggg ctatggactt agaaaatcaa
    38461 aacagagtta aagatgctgc tgataaattc ggagctgaaa atgttgtgat tttactaggt
    38521 gctgctgaag ccgaagctgc aggtcttgca gccgaaacag taactgctgg agatccaact
    38581 ttcgctggac cacttgctgg agttgcctta ggattaagtg tttaccacgt tgttgaggaa
    38641 ccaataaaat cattatttga tgaaagtgta tatgaggacc aaataagtat gatggaaatg
    38701 gttttagaag ttgaagaaat agaagaagaa atgtctggta taagagaaga attttgtaaa
    38761 ttttaatgcc taaaagcaaa aggggtgaaa ctaagagatg ggaaaactaa aagcagtaca
    38821 ttatattaat cagttctttg ctggtatagg tggagaagaa aaagctgata ctaagccaca
    38881 tgtggcagaa actttacctc caataagttt acaacttgat aaattattag gtgaagatat
    38941 tgaaatagtt ggaacagtag tttgtggaga tagctatttc aatgaaaata tagatagtgc
    39001 aagtgaagaa gttttatcaa tggtaaaagg ttttgaacca caacttttca tagctggtcc
    39061 tgcatttaat gctggtagat atggggttgc tgctggaaca ataactaaag ttgtaaaaga
    39121 tgctttgaat ataccagctt taacaggtat gtatgttgaa aatccaggag cagatatgtt
    39181 caaaaaggat gtttatgtag tagaaacttc tgattctgca gcaggtatga gaaaggcact
    39241 tcctaagata gctaaacttg cagtaaaact tgctaatgga gaagaaattg gaactcctaa
    39301 agatgaagga tacatagcta gaggaataag agttaactac ttccatgaag acagaggttc
    39361 taagagagct gttgacatgt tagttaagaa aataaaaggt gaaccatttg aaactgaata
    39421 cccaatgcca aactttgata gagttgaccc aagtaaagct gtaaaagatt tatcaaaatg
    39481 taaaatagct ttagttactt ctggtggtat agttccaaaa ggaaatccag atagaataga
    39541 gtcttcttca gcttctaaat atggaactta ttctatagca ggagttatgg atttaacaga
    39601 agagacttat gaaactgcac atggtggata tgacccagtg tatgcaaatt tagatgcaga
    39661 tagagtatta cctgttgatg ttcttagaga tttagaaaaa gaaggtgtaa ttggaaaatt
    39721 acatgagact ttctatacaa ctgtaggtaa tggtacatct gttgcaaact ctaaaaaata
    39781 tgcttctgaa attggagcag cattagtggc tgatggtgta gatgcagtaa tattaacttc
    39841 tacatgaggt acttgtactc gttgcggtgc aacgatggta aaagaaatag aaaaaactgg
    39901 acttccagta gttcatatgt gtacagtagt acctatttca ttaacagtag gggctaatag
    39961 aatagttcca actatagcaa tacctcatcc acttggaaat ccagcgcttg accctacaga
    40021 agaaaaagcc ctaagaagag gccttgtaga aaaagcatta aatgctttaa ctacagaagt
    40081 agatggtcaa acagtatttg aaaaataaaa ataacacaca catatattat atagataaaa
    40141 atataaacac acactaaaaa taaaaaataa ctatacacaa aaaaataata tagatttcat
    40201 gaatggataa attggagtta ttcattcatg aaatcttaaa aaatgccaaa atacataaac
    40261 aataatagaa tcaaatatac aataaaatac aatgattaga gcttttaata agtttaataa
    40321 gattaaaaaa taagtgttca taaaatttat ggaggtgcac aaaatgactt atccagtttt
    40381 aaaaggggca ggctatgtac ttattcatac tccagatatg atagtgcaaa atggaagtac
    40441 ttgtacagtt gaaagagcaa caaatccaga ttcagaattt ttaaaagaag taagtaatca
    40501 tataagaagt tatgaagatg tagttaacta catgccaaat caagtttata taggaaatag
    40561 aagaccagaa gaattaagag atttaccaat gccatggtgt gaacaaaaga ttgagggaac
    40621 tagaaatggt aagtttggag aaataatgcc tcaagatgag ttcatagctt taatgcaaat
    40681 aagtgatgca tttgatttag taaaattatc acaagaattt attgatgaag taaagccaaa
    40741 aatcgaaaat aactaccctg aaattgcacc atttgtaggt aaattaaagg gtgatgatat
    40801 agaagaaggt aaagaattag tagcaacaca catagctgaa ggattatacc atgatggaaa
    40861 atttgttggt tatgtaaaaa gagcacatga tgtagatgtt aacttaaatg cccatacaat
    40921 gtttgaaaat ctagtagtaa aagcatctgg agttttatct gctattcaaa tgctaagaca
    40981 tagcaaaata gaccctgctg aaatagatta tgttattgag tgttcagaag aagcttgtgg
    41041 agatataaac caaagaggtg gaggaaactt tgctaaatca atagctgaga tagcaggact
    41101 tcaaaatgca actggttctg acacaagagg attttgtgca gcaccaactc atgcattaat
    41161 tcaagcagca gctttagtaa aagctggtat acataaaaat gtaatggtag tagcaggtgg
    41221 agcaagtgct aaacttggaa tgaatgctaa agaccatgtt aaaaaaggtc ttcctgtact
    41281 tgaagatgtt gttggaggat ttgcagtact tgtatctgaa aatgatggtg taaatccagt
    41341 tataagaact gatttaacag gtaagcatac tgttggaact ggttcttcac cacaagcagt
    41401 tatgacagca cttataactt caggtcttga tagagctaat ttaaaaataa cagatgttga
    41461 tgtgtattca gttgaaatgc aaaacccaga tataactaag ccagcaggag caggagatgt
    41521 tccagaagca aactacaaaa tgataggggc acttgctgtt aaacgtggag acttagaaaa
    41581 gaaagaattg aaagattttg tttctaacaa aggattacca ggatgggcac caactcaagg
    41641 acatatacca tcaggagctc cttatatagg atttttaata gatgatttaa ctacaggaaa
    41701 tagaaataga gctatgatag ttggaaaagg tagtttattc ttaggaagaa tgactaactt
    41761 atttgatgga gtatctttta tagctgaaag aaatacaggt gttactgaag agacttcagg
    41821 aatatctaag gatgaaatta agaagataat agctgaatct atgaaaaaac tagcattaga
    41881 tatgttagaa gaataggggt gaggatatgt caaaaaaagt aatcgcagat gtattcttag
    41941 aagtagctaa tgcaatagaa agcggcgaat ttggcaaaaa agtaaaaatt ggtgttacta
    42001 cacttggaag tgaacatggt gtagaaaaca tggttaatgg tgcacaatta gcaaaatcta
    42061 atttatttga tattgtgctt attggaccaa aagtggaaac tgaccttgaa gtagttgaag
    42121 ttaatgatga aaaagaaatg catgcaaaaa tggaagaatt attagattca ggatatattg
    42181 atgcttgtgt tactatgcat tataattttc caataggtgt atctacagta ggtagagtaa
    42241 taactccagc aaaaggaaaa gaaatgatac ttgcaacaac aacaggaaca agtgctacta
    42301 atagaataga ggcaatggta agaaatgcca tttatggtat tgctacagct aaatcaatgg
    42361 gtaacaaatg cccaaaagtt ggaatactta atgttgatgg agcaagacaa gttgagaagt
    42421 gcttaaaaga attaaaagat aatggatatg acatggagtt tgcggattca attagagcag
    42481 atggtggatg tgtaatgaga ggtaatgatt tacttgtagg tgcacctgat gttatggtta
    42541 ctgatacatt atctggaaat atatttatga aagtattttc ttcatatact acaggtggag
    42601 attatgaagc tcaaggcttt ggatacggac ctggagttgg agaggactat gatagaaagg
    42661 tacttatagt atcaagagca tcaggttctc cggtagtagc aaatgcttta aaatacgctt
    42721 atgatgttgt aaagggagat ataagtaatg ttgcaagaaa tgaatttgca aaggttaaaa
    42781 aagcaaaatt tgatgacatt atatcctctc ttactaaaaa agaagttaaa gctgaaaaag
    42841 tagaagttaa aatgccagat aaagaaattg ttactcgtca aatagctggt gttgatataa
    42901 tggatttaga agatgcagta tctgagttat ggaaaaacgg aatctatgct gaaagtggta
    42961 tgggttgtac aggtccaata gttttagtaa atgaagctaa aggagactta gcagttgaaa
    43021 ctttagttaa agctggatat actgcaaaat aagtacattt tttatatgta aataagaaca
    43081 tatagttata attttattga ttataattat atgttctttt tattttatat cttgtcaata
    43141 tttatatatt aacacaatcc atttatttga ttctctagct aatttattat atttattcag
    43201 ttaaaattaa gctttctaac taaataaaaa ctaatgaagt attaaaatga aattgataaa
    43261 atatgaaaaa attttaggaa taaagtatct gttagataaa aataagatta attagtgata
    43321 taatataatt aagataaaat ttattatttg gaggcaaaat catgagcaga gtaaaaaatg
    43381 tagtagaatt gttggaaact aaaggtgttg atgcactata tctaacaaag aaaactaatg
    43441 taaactatat aagtggtttt cctgatgaag aagcatatgc agtgatttgc aaagatggaa
    43501 actttttagt tactgatagt agatatatgg agcttgcaga aaaggtttgc aaagattttg
    43561 aaattataaa ttggcataat tttgatagaa gtgtggcaaa ggcagttaaa agtgtatgtg
    43621 ataaagtggg tataaagaaa cttgggtttg aaagaactaa tatagtgttt gataaatatg
    43681 aagaacttaa aaatctgatt gagaaggata atggagaatt aatacctaca gaaaatattg
    43741 tagagacttt gagatatgta aaagacaaag atgaaatcaa aaatacaaga aaagcttgtg
    43801 aaatagcgga taaggcatta gaagaattga ttccacatat aaaagctgga gttagcgaaa
    43861 ttgaactggc tacaaagtta gagtacttta tgaaaatgaa cggagcacaa aatatagggt
    43921 ttgaaactat actgatatca ggagcaaaga cttcattgct tcatggtaag cctagtgata
    43981 agattataga aaaaggtgat tttgtactta tagactatgg cgctatgtat aatggctata
    44041 tatctgatac aactagaact tttatagttg gaggagcttc tgaaaagcaa ttagaaatat
    44101 ataatttagt taaggaagct caaaatgtag gggttgagaa catgaaagct ggtgtacatg
    44161 cgacaattcc agatgctgag ataagaaaag ttgtcaaaaa atatgaagac tattactatc
    44221 aaggtatagg acatggagtc ggtagagatg ttcatgaaga acctttcatt ggtaattatg
    44281 gtgataaaat catagaagag ggatgtataa taacaatgga accaggtatt tatttccctg
    44341 gatggggtgg agttagaata gaagatactg ttttgattac taaaaatggt ccagaaagac
    44401 ttactaaatt ccctaaagat ttgatgattt tagacaaata atttaattta tatatatttt
    44461 tttacataaa atataacata atctcactat taagctctat ttacatatta tagtaaagag
    44521 ggcttaattt tattgtgaga ggtgatagta tatatgtata aaaaacataa atttataaaa
    44581 aatataaaaa aagcctggta taaaatcaaa ttaattgata gatgccttat aattgtaatg
    44641 gcaatattaa tgtttcaatc tatatataat ttatttgtta atgaagtaaa ttcacaagat
    44701 actacaacta ttgatgtagt agtaagaacc acttcagcag ctatatttgg gtatttttta
    44761 agtgctaatt ttataaagag acctttaagg aagtatacaa atactgatgt atcttcaaat
    44821 ctttttatag ataataattt atccccaaaa ggtcaagagt ctaatcaaaa taatataatg
    44881 aatgtcaaaa ataccattgg atttacttca gaagctgata attatgaaaa gaaaatacct
    44941 attaataata atgaaggttt tgaagaagga gaaactagtg aattgcaaat tattatagct
    45001 actgtaattt gtatagtagc attaacagta ctttttgttg taagaaattt tacaactaca
    45061 acatcagctt ctttaggtac tatttcacag atgagagatt ttgtctcagg atgcgtgggt
    45121 tttttgctag gttgtccaag taaacctgat taaaaaagta ttatcaataa aaggtatttt
    45181 aaaaagtatc agtataataa tatttagatt taaatgtata caattataat tctaaacatt
    45241 ctatattgta tttttatact gatactctaa actatactat ttattaaaat attttaacat
    45301 tgtatttaaa caaaatatta tatctgtata atataaattt agtttatatg aatagatgcc
    45361 atatactcaa taaaaagttt catactatga gatatgtatt gatttcttct ccaaagaacc
    45421 ccaatattcg cagtaattgc acgttctaat ggtattgaac agagattttc tgtattttga
    45481 aatatttctt tatacaatat tgttgaagcc aagtcatttt ctagtaaata acgtatggta
    45541 gaaagttgat ttgagtgtaa aattatattt ggcttagctt tttcaagtct ttttgtaata
    45601 atcttatagt gataagaacc ttcagataag attacaaaag gtacattttt taacatataa
    45661 ttcgatataa tgggatgttt tgccaattca tttttgggat ttgtaactaa gtataattct
    45721 gttttataga ttgtctttga atctatatca tcataaatat cactgtcaat tataccaata
    45781 caaaaatcaa gtgtagattc ttcaatcatt ttagctccaa caaatgttgg aacttcaaaa
    45841 attttaagct ctatatctgg ataaattaca ttaaatctag gaagtatttt tgaaagcaaa
    45901 aacgtaccta aaactgtagg aatacctatt ttgagagaag cttttctctt ttttcctaaa
    45961 tcaagtgcgt cacattgaaa atcctcaaat tgttttataa aatgttttga cttgtctaaa
    46021 aaaatttttc cttcaggcgt taactctatt ttattaccta ttctgtaaaa aagttcaaag
    46081 ccaagttctt tttctaattc tttaattgct aatgttatgg atggttgaga aatatgaata
    46141 ctttccgcag ccttagtcat gtttttatat ttacagacag tttgaaaata gtataaatag
    46201 tttatattca tttggtatta gttcctttca tttacatatt agtgacaagt atataattaa
    46261 caatagcata agttttgtat attgttgtaa aaaaatagaa tagttttaaa ctatcatagc
    46321 ataagttttt gatattttca atctattaag aatagtgcta ttattaaatt aacaaaagag
    46381 aatagctggt atggtttaga gtaaatcaat ctatattaca gttatatcaa cgaatatcaa
    46441 aaaattatct attagaaaat aaaaattatt tttacaatta aattgttaat taaatcataa
    46501 agaaaaaagt gatattaaca agataaaatt tttttaatca gaaatgttaa tttaataaca
    46561 aaatagagta ttggggagaa aggagaaata tattttttaa taatatttgt taatttaata
    46621 acgaaaaatg aaagggagtg atttagtgaa gtttgaattg atggattttt taatgaatcc
    46681 ttttgtcctt atgtttgctg cagtaattac aggaatttta tttggaaaaa ttaaatttgg
    46741 gaagtttaat tttggggtat caggagcatt atttacagga ttatttattg gatggcttgc
    46801 atatagcttg gggaatctaa taatagcaaa aggggaaaca gcagcaggat ataaggcagc
    46861 aactgtaatg atgggtaatg gaattatttc ttctgacttc tttgatttct ttttaataat
    46921 atttgttgca gcagttggtc tattggcagc aaaagatatg aaagctgtat taaagaagta
    46981 tggagcaaga tttgtaattt taggagttct tataactttt ataggtggct ctatgactta
    47041 tgcaatgact ttactatcaa gtgataaagg aagtagtgct tatgaagttt ctggcgttta
    47101 cacaggagca ttaacaagtt cgcctggatt agctgctgct ttagaaacag ctggtaaaca
    47161 tgcagaagat gtatcaaaag aatttgaaaa agcttcaata aaagataaaa aagaaatttt
    47221 aaaagtagtc gacccagaag gcaaattgga tgtgaataca actacatcac tgactcaaga
    47281 gcaaatagat aagtatattg catatgctga agctggtgtt ggtataggtc atgcagtcgc
    47341 atatcctttt ggagttttaa tagtaatctt aggtgtaaat ttccttccaa aattatttag
    47401 gatggaccta aaagaagaaa gaagaaaata tgagaaggaa atgaaggaag caagagatag
    47461 tgtttctggt aaaacgatac cagaagttcc atttaatata ataacatttt tcttgacatg
    47521 tttagctgga tacttagttg gaggaataca tgtatttatg ggaccactag ggtacttcac
    47581 actaggcgca acaggaggtt cactaattgt atctctagtt cttggatata taggtaagat
    47641 aggggtagta aatttcagaa tggaagaaaa ggttttaaat attttaaaac aaatagggct
    47701 agtatttttc ttagcaatag ttggattaag atatggtgga aaagtagttg attcaattat
    47761 gacatctggt atgcacctag ccttagtagc aatagcagta ggtgttacag ctatgatgat
    47821 aggattctta gttggcaaat acgtatttaa attaaattgg attttattat ctggagctgt
    47881 ctgtggtggt atgacatcaa caccaggtct tggagctgct gttgatgctc ttgatagtga
    47941 tgacccagca gcaggttatg gtgctacgta tccatttgca ttattaacta aagttatatt
    48001 ggttatagtt ttacacaaac ttccaatgta aataagattt tatatggggg gatatttatg
    48061 aataatgaag gagcatttga agaattaagt ggaagattaa gaaataaaga attgtgtgat
    48121 ttaataatga atgcagatga agctgctaaa attatagagg atggcatggt tattggagtt
    48181 agtggattta caccttcagg ctatccaaaa gcagtaccat tagcagtttc agaaagagct
    48241 aaaagtggag aaaagataaa attaaccgta tattcaggag catctttagg tccagaagtt
    48301 gatggagcat ggtcagaagc aggtataatt gaaagaagac ttccttatca aactaattca
    48361 atacttagaa ataatattaa taaaggtgtt gttgattata tagatatgca cctaagtcat
    48421 tctactcaat ttttaaatta tggaactata cctaaagtag atgtagctat agtagaagca
    48481 cttgcaataa ctgaagaagg aaatattata ccaactagtg ggataggtaa ttctccatct
    48541 tttataaaaa gtgcagataa agtaatagta gagataaatc ttgcaaaacc aatggaaatg
    48601 gaaggtatgg cagatatata tattacggaa aatccaccaa atagaaaacc aatagaaata
    48661 aatcatccta aggatagaat tggaacaaca tatatacctt gtggtttgga taaaattgca
    48721 ggagtagtaa ttaccaatat gcaagataag acccgtccat tgggagttgt agatgaagct
    48781 tcgaaaaaaa tatcaaataa tattattgct tttttaagag aagaagtaaa ggcaggcaga
    48841 ttatcaaaga atttacttcc tcttcaatct ggtgtaggaa gtgtagcaaa tgcagtatta
    48901 tatggattat gtgaatctga atttgaaaat ttaacttgtt atacagaggt tgtacaggac
    48961 tctatgttgg atttaataag aatgggtaaa gttacaatgg catctactac atctgtaagt
    49021 ccatctccag aaggattaat aaaatttgaa aaagatattg atttttttaa ggataagatt
    49081 atattaagac ctcaagaaat tagtaacaat ccagaaatag ccagaagaat tggtgtaatt
    49141 gcaatgaaca ctgcaattga agttgatatt tatggaaatg taaattctac tcacataatg
    49201 gggtcaaaga tgatgaatgg aattggtggt tctggtgatt ttgctagaaa tggagcaata
    49261 actatattta gtactgagtc aattgcaaaa aatggtgata tatcatcaat agtacctatg
    49321 gtatctcacg tagaccacac tgaacatgat gtaatggtaa ttgtaacaga acaaggatat
    49381 gctgatttaa gaggtcttgc acctagagaa agagctataa aaataataga aaattgtgcc
    49441 catccagatt ataaagaaca acttagggat tatttaaata gagcttgtaa aagtggagca
    49501 aaacaaacac ctcacatatt ggacgaagct ttatcatggc atagtaaatt tatgagtaca
    49561 ggtacaatga aaaaggctga aacttttaaa agtgcattat aaaatattta ataaattgga
    49621 ggtagatttt aaatggaaaa agcagtggaa aactttgaag atttaagtaa ggaatacatt
    49681 aatggttata ttgagagagc aagaaaagct caaagagagt ttgaatgtta tactcaagaa
    49741 caagtagata aaatagtaaa aatagttgga aaagtagtgt attataatgc tgaatattta
    49801 gctaaacttg ctgtagaaga gactggaatg ggagtatatg aagataaggt agctaaaaat
    49861 aaaagcaaag caaaagttat atataacaat ttaaaagata aaaaatcagt tggtataatt
    49921 gatatagata gagaaactgg aataacaaag gtagctaaac cagttggagt agtagcggca
    49981 ataactcctt gtacaaatcc aatcgttaca cctatgagca atgcaatgtt tgcacttaag
    50041 ggaagaaatg caattattat cacacctcat cataaagcaa ttggatgtag tacaaaaact
    50101 gtagagatga ttaatgaaga attagaaaaa ataggagctc cagaaaattt aatacaaata
    50161 cttgaccaac aatcaagaga aaatacaaga aatttaattt catcagcaga tgtagtaatt
    50221 gccactggag gaatgggaat ggtaaaagct gcgtactcaa gtggaaaacc agcacttggt
    50281 gtaggggcag gaaatgttca atgtatcata gatagagatg tagacattaa agaagcagta
    50341 cctaaaatca tagcaggaag aatttttgat aatggtatca tttgttcagg tgaacagtca
    50401 gtaatagtag cagaagaaat gtttgataaa ataatggatg aatttaaaaa taataaaggt
    50461 tttatagtta gagataaagt acaaaaagaa gctttcagaa atgctatgtt tgtaaataaa
    50521 tctatgaata aagatgcagt aggtcaatca gttcatacaa ttgcaaaaat tgcaggtgtt
    50581 gagataccag aagatacaaa aataatagta atagaagctg atggaccagg agaagaggat
    50641 attattgcaa aagaaaaaat gtgtccagtt atatctgcat acaagtataa aagttttgaa
    50701 gaaggtgtag ctattgcaaa agcaaattta aatgtagaag gaaaaggaca tagtgtatct
    50761 atacattcaa atacagttaa aaatatagaa tatgcaggag aaaatataga agtatcaaga
    50821 tttgttatta atcaatgttg tgctactagt gctggaggaa gtttctttaa tggtcttgca
    50881 cctactaata ctctaggttg tggttcttgg ggaaataaca gcatctctga aaatcttgat
    50941 tataagcatc taattaatat ttctagaatt gcttattata tgccagaaaa tgaagtccct
    51001 acagatgaag aactttgggg ataaaattta gacaaaaaat attcattcta aattaaagta
    51061 ggaatatatt ttaatttaga atgaatttaa gacataaatt aaatttaaat tagtttattg
    51121 gactaaattt aaaatattaa gagacatata gaagaaggaa gtattataat ttaaaataaa
    51181 taaaaaaatc tataaaagag aaggagtggt tttattatgg cattaatgac aggagctcaa
    51241 tatattgaaa gtttgagaaa attaaatact aaggtttata tgtttggtga agaggttaag
    51301 aattgggttg accatcctat gattagacca tctataaatt gtgtagcagc aacttatgac
    51361 ttagctcatg acccagaata tgcagattta atgacagtta cttcaaatat cacaggtgaa
    51421 aaaataaata gatttggtca tcttcatcaa agtgttgatg atttgataaa aaaagtaaaa
    51481 atgcaaagac tatgtggtca aaaaacagct tcttgtttcc aaagatgtgt tggtatggat
    51541 gcgtttaatg cagtgtattc aacaacattt gagtgtgata aagcccatgg aactaattat
    51601 catgataatt ttgtaaaata cttaacttat atacaagaaa acgatttagt agttgatgga
    51661 gctatgactg accctaaggg agatagaagt ctatcaccta gtgctcaacc tgacccagat
    51721 atgttccttc atatagtaga aagaagagaa gatgggataa ttgtaagagg agcaaaggca
    51781 catcaaactg gttcaataaa ttcacatgag caccttataa tgcctactat aagtatgact
    51841 gaagcagata aagactacgc tgtatcattt gcagttcctt cagatgctga aggagtgttt
    51901 atgatttatg gaagacaatc ttgtgacact agaaaattag aagaaggtgc agatgttgat
    51961 ttaggaaata aggagtttgg aggtcaagaa gctttagtag tatttgataa tgtatttgtt
    52021 ccaaatgata gaattttctt atgtggagaa tgggatttct ctggtatgtt agtagagaga
    52081 tttgcaggat accatagaca aagttatggt ggatgtaaag taggagtagg tgatgtaata
    52141 ataggagcag cagctttagc agctgattat aatggagcaa acaaagcttc acatataaaa
    52201 gataaactaa tagaaatgac tcaccttaat gaaagcttat attgctgtgg tatagcatgt
    52261 tcatcagaag gtcacaaaac agaagctgga aactatcaaa tagatttact tcttgcaaat
    52321 gtgtgtaaac aaaatgtaac tagatttcct tatgaaatag taagacttgc agaagatata
    52381 gctggagggc ttatggttac tatgccttca gaaaaagact ttaaatcaga ccttaaagtt
    52441 ggaacaagtg gaatgactat tggcgaagta tgtaacaagt attttaaagc ttcttcagtg
    52501 gcttcaacag aagaaagaat gagaatatta agattcttag aaaatatatg ccttggttca
    52561 tctgctgttg gttatagaac tgagtcaatg catggggcag gttcaccaca agctcaaaga
    52621 ataatgattt caagacaagg aaacataaat caaaagaaag aattagctaa gaaaattgcg
    52681 ggaataaaaa aagaggaagc tttaaattta taaaaagttg atatataaag ggaaattata
    52741 tattaatgtg tgttaattaa tgaaaaaata tgtagtataa gagatagtta taaaattatg
    52801 gtggttttta gctaagtaaa gaaattttta ataaggagaa tttacacatg acctgtggag
    52861 ttagattttg tgggggctgt aaccctagat acgaaagagg gaaggctctt acaataatca
    52921 aagagcactt caatggtagg gtagatttta gtatagcaca agagaacgtc gagtatgatt
    52981 tgttacttat aattggagga tgcgcaactc tatgcgcatc ctatcaacaa tataaagtga
    53041 aaaatgaatg tgttaagatg tgggatttta gccatataga aagagttata aatgtgattg
    53101 aatcagcaat ttgtgaaact taaaaaagct aaatgggggg atttcattga gttggcaaga
    53161 attgtatcaa agtaaattat gtagtgctac agaagctgta aaacagatta aaaacggtga
    53221 tactgtagta tttgcacatt gtgtaggtga acctcctgca ctagtagaag ctatgattga
    53281 aaatgctgaa caatataaag atgttgagat taaacatatg gtaagcttgg gtagtggtgg
    53341 atatactgct aagggaatgg aagctcattt tagagtaaat ccaatgtttg taagtggaaa
    53401 tgtaagaaag gcaattgaaa atggagatgg tgattttaca cctgcattct tccatgaagt
    53461 accaaagttg cttagagaaa aaagattaaa atgtgatgtt gttttagcac aggtaactcc
    53521 accagatgaa catgggtatt gtagcttagg aacatcagtt gattatactt atgaagccat
    53581 taaaactgct agaacagtaa ttgttcaagt gaatgaccag tttcctagaa cctatggtga
    53641 ggtagtccat gtatcagagt ttgactatat agtggaaaaa tcacaacctt tatttgaact
    53701 acaacctgca aagattggag aagtagaaga agcaattggt aaaaattgtg cttcattaat
    53761 tgaagatggc tctactttac agctagggat tggtgggata ccagatgcag ttatgttatt
    53821 tttaactgat aaaaaggatt tagggattca ttcagaaatg atttcagatg ggactttggc
    53881 cctttatgaa aaaggtgtta taaatggtaa atataaaaat tttgataaag aaaaaatgac
    53941 agttaccttc ttaatgggta ctaaaaaatt atatgacttt gcaaataata accctgcagt
    54001 agaggtaaaa ccagtagact atgtgaatca tccagcaatt ataatgaaac aacataagat
    54061 ggtttctata aattctgcta tacaagttga tttaatggga caggtagttg cagaggctat
    54121 gggacttaga caatttagtg gtgttggagg tcaagttgac tttatacgtg gagtgtctat
    54181 gggtgaagat ggaaaggcaa ttatagctat gccttcaata actacaaaaa aagatggtac
    54241 agtaatttca aaaatcgtat ctattgtgga tgaaggtgca cctataacga catcaagaaa
    54301 tgatgttgac tatattgtaa cagaatacgg tatagcagaa ttaaaaggaa aatctcttag
    54361 agaaagagca agaaatttaa taaatatagc tcatccaagt gtaagagaac atctagcagt
    54421 agaatttgaa aagagattta aggagaaata ttaataatag aggggtgtta ataatggaag
    54481 cacttagagt agttccaaag atattttact ttgatacatt taaagaattt aatgaagaat
    54541 ttaaaatagg aaaaaatgat ttagtaatta ctaatgagtt tatatatgag ccatatatga
    54601 aacctcttgg aatagataca aatttaattt ttcaagaaaa gtttggaaca ggtgaaccat
    54661 ctgatgaaat gatagactcc atgacaaagg aaatgaagaa atacaatttt gatagaatta
    54721 ttgcatttgg aggaggaaca atagttgata tatgtaagat attagcactt gatgttccag
    54781 aaaagtctat tgatttattt gaaggagaag tatcacctaa aaaagtaaaa gagttagtag
    54841 tagttcctac aacatgtggt acaggtagtg aagtaacaaa tgtagctatt gcagagttaa
    54901 aatctaaaca tactaaaaag gggcttgcag tagaagaaac atatgcagac tatgcagtgt
    54961 taattccaga gacagtaaaa gggttacctt acaaattctt tgttacaagt tcggtagatg
    55021 ctcttataca tgctattgag tcttatcttt ctccaaaagc aagtccattt acagagatgt
    55081 attctctaca agcaataaaa atgattatgg atgggtataa gaagatagtt gataaaggag
    55141 aagaagagag atttaatcat cttagagact ttgtacttgc atcaaattat gcaggaattg
    55201 cttttggaaa tgctggttgt gcagcagttc atgcactatc ttattcaata ggtggagctt
    55261 tccatgttgc acatggtgaa gcaaattatc agttctttac tgaagtattt aagatgtatt
    55321 ctagaaaaaa acctaatgga aaaattataa aatgtacaaa aattttagca gatgcccttg
    55381 aatgtgaccc taactgtgat gtttatggag aattagaaaa gtttttaaat aaattaatag
    55441 ctaaaaaagc tttgagagaa tatggaatgg tggaaagtca gatagatgaa tttacagata
    55501 gtacaatagc aaatcaacaa cgactacttg ctaataatta tgtagagctt agtagagagg
    55561 aaataagaga gatatttgca aatctttatt aatacaattt tttatttata tgtatagtca
    55621 acataaacaa tgctaattat atttatgtac aaataaaaat aagggaactt aaattttaat
    55681 taaagttaag ttctcttatt tttatatgga gttaaatata agtatatttt taatttaaaa
    55741 tatgcttata tttaagtcta ttactttatt tgaaacaatt tgtagaattt caaattcctt
    55801 gacagtaata agtaagtaat tgtataatca aactgcaata tattaataat attagtgaaa
    55861 atgaaaggat tataaaatat gtataaatca gaaaattttt caaaaaaatc tgtattaata
    55921 aattcatttt taagtaaatt tttaaaaata attggatggg gtttggtaag cttatttaca
    55981 ttatcagcct tagtactttc aactatttcc attataattg gatgggctgt aatacttcct
    56041 attcaagtat gtgcagtatt tttacttata ggaggagttt gtatttttaa aggtaagaga
    56101 ttaggagacc aaatttctcg ttataaaaaa tattgtacaa ttataaacaa tagaaatatt
    56161 attccagtag aacttattgc agaaaacaca tctaaatcat taaattttat aataaaagat
    56221 gtacaaaaga tgatagacaa aaactacttt ataaatactt atattgataa aagaaataat
    56281 cagattgtgt taacaaatga agattttgtt ccaccaagat atgaagatgt agcatatgaa
    56341 gtcaaagaag aagaaaagac tgatgaatcc aatgaagttg atacaattat aaataaagga
    56401 atgaattatc taacacaaat aaaagaagct aataaaaata ttaaatcaga atcaatgggc
    56461 gataaaattg tacaagtaga agatgttaca agtaaaatat ttgatgttgt aaaacatgac
    56521 ccatcaaaac ttactcagat acaaaaattt atggattatt atcttccaac cactttaaaa
    56581 ctattaaatt catatcatac attggaagaa caaggaattg atagagaaaa tataacaaca
    56641 actatggaaa gtattgaaaa tacaatgaat acgattgtag tagcttttga aaatcaattg
    56701 gactatctgt ttgaagatga agccattgat atttctacag atattactgt tttagagaat
    56761 atgttagtcc aagaaggatt aacgagtggt aaattttaac ttcaatagaa aaaatattct
    56821 gttattttta aacaattaat tagtcataaa gtataaaatg tgtattatat aagttaatca
    56881 gtactttatg aaggaagagg agagaaagat acaatgaata atttagatga tataccagtt
    56941 atgccaactt tgacacttga cccatttgga gaagaatcaa acactaatga tatagataat
    57001 tctgacttat taatgaaaaa ggatgaaaaa gacccagaag aagaaaaact gtctgaatct
    57061 gaacgcaaga tggtaaagga atttgcggaa aaaatagata ttacaaatac aaatatgatt
    57121 ttgcaatatg gagctggagc tcaaaaaaag gtagcaagtt tttctgaaac agctttaaag
    57181 agtgtaaaaa caagagattt aggagaagtt ggagatatgc ttacaaatct agttactgat
    57241 ttaaaagcat tttcagcaga tgaaaaagaa caaagtggtt ttttaggaat ttttaaaaag
    57301 gcaaataata aaatttcaaa tttaaaaact aagtatgata gtgcagaggt aaatgtggat
    57361 aaagtaagca aagagcttca aaagcatcag gttaaaatat tgaaagatat agcaatgctt
    57421 gataagatgt atgaattgaa cttagcttac tcaaaagagc ttactatgta tattatagca
    57481 ggaaaacaaa aattaaagga tatgaaagaa tatgaaatgc caaagttgag agaaaaagct
    57541 cgtttatctg gttcaacaga agatgctcaa tctgtaaatg atatggtttc actttgtgac
    57601 agatttgaaa agaagattca tgacttagaa ttaactagaa tggtatcgct tcaaatggct
    57661 cctcagataa gattggttca aaatagtaat aatctgatgg cagaaaagat tcaatcaact
    57721 atagtaaata ccattccatt atggaaaaat caaatagtgc ttgctcttgg aatttctcac
    57781 ttaaatcaag ctatgaaagc acagcgtgaa gttagtaata tgacaaatga gcttttatta
    57841 aagaatgcag aaactttgaa gatgggaaca atagaaacag caaaagaatc agaaagagga
    57901 attgtagata tagacacaat taagaaaact aatcaatctc taatatctac tattgatgag
    57961 gtagttaaaa tacaacatga tggtagaata aagagacaag aagcagaagt tgaattatca
    58021 aaaatagaaa atgaacttaa aagtaagctt cttgaattta cagttaaata aaaattatac
    58081 taatataaaa agagactgtc tcaaaataga gataagtctc tttttcattg tttaaatgat
    58141 taaagtatat ttatattata aatttctatt atcttttaac ataacatcat gagctccacc
    58201 ttcaactata ctagtagaag atacaagtgt aagtttagca tttttttgaa gttcaggaat
    58261 gctaagtgct ccacagttac acatagtaga acgaacttta cttaaagaaa gagttacatt
    58321 gtctttcaaa gaaccagcat aaggcacata agagtcaaca ccttcttcaa aagaaagttt
    58381 cttatctcca ccaaggtcat atctttgcca gtttctagca cgagcagaac cttctcccca
    58441 atactctttc atataactac catttatatt aactttgtta gttggactct catcaaaacg
    58501 agagaagtat ctaccaagca ttataaaatc tgcacccata gctaaagcta aagttatatg
    58561 atggtcataa acgataccac catcagagca aattggaata taaatacctg ttttttcaaa
    58621 gtattcgtct ctagcttgag caacttcaat tatagaagta gcttgtccac gtcctatacc
    58681 tttttgttca cgagttatac atatagaacc accaccaata ccaactttaa cgaagtcagc
    58741 accagcttca gctaggtaaa ggaatccttc gcggtcaact acatttccag ctcctacctt
    58801 aactgtatca ccatattttt cacgaatgaa atcaagtgtt attttttgcc actcagaaaa
    58861 accttctgaa gaatctatac ataaaacatc agcaccagct tcaactaaag caggaacacg
    58921 ttcagcaaag tctctagtat taataccagc tccaactaca tatctcttag aagaatctaa
    58981 aagttcaagt ggattttctt tatgagaaga gtaatcttta cggaatacca tatacataag
    59041 attaccatta tcatcaagta caggaagaga attaagtttg tggtcccata taatattgtt
    59101 tgcttccttt aaagtaacat ctttgttagc ataaactata gatgacatag gagtcataaa
    59161 ttcactaact ttagtatcta aatccatacg acttatacga taatcacgac ttgcaacaat
    59221 acccaataat ttaccagttg aagttccatc ttcagtaaca gctactgtag aatgtccagt
    59281 tttttctttt aagtcaagta tgtcttttaa tgtgttatca ggtttaatat ttgaatcact
    59341 tacaacaaaa ccagctttgt gggatttaac acgtgctacc atagcagctt cattttcaat
    59401 agtttgagaa ccgtatataa atgaaatacc accttcttta gcaagtgcaa tagccatttt
    59461 gtcatcagaa acagattgca taatagcaga agtcaaaggt atattcatat aaatatctgc
    59521 ttcctcgccc tttttaaatt tagtaacagg tgtttttaaa cttacattag caggtataca
    59581 atcagtagaa gagaaacctg gtacaagaag gtattcactg aaagtatgtg atggtgtatc
    59641 aaaataaaac gccatttttt aatcactcct tatattttta tactttttat aattgatagt
    59701 attaattata acttattctt taattttatt aaagtatttt gtcaaatatt gagatttttg
    59761 aaaaatttaa actattttaa ttaaatttgt ttaatatata ttgccttata gggtaaagtt
    59821 gtatattaaa taatgtttag tgtttaatag tagctaattt aaaattaatc tttagtgatt
    59881 catataatta catttgtata gtttacattg ataatattac tagagagtgc ataaacctca
    59941 aaaatacaga taaattaaat ctatattagt atatccaaaa gtacatttaa taaatttatt
    60001 taactgaatt attattttca tttctattaa atttaaatat tttataaaaa tagtattatt
    60061 tacaaaatca tatactccaa aatactacat aaataaaatt aaacaaaaac taaaatgaca
    60121 aatgtcatta tctaaagtga catagaaacg gtttcttaaa gttgttacta taaaatataa
    60181 actctataat aaaagtataa caaaagggaa tcatatcgat atagaatata attcaagagg
    60241 aggtaaaatt atgagtagtt ctaatcaatc gacaataaag acatctatac agcgagtagg
    60301 gaaattttta agtggtatgg taatgccaaa tataggagct tttatagcat ggggtcttat
    60361 aacagcatta tttataccaa caggatggat gcctaatgaa aaattgagta ctataggtga
    60421 cccaatgata aaataccttt taccactatt gatagcttat actggtggta aagcaatagc
    60481 aggacaaaga ggtggcgtaa taggtgcagc agcagctatg ggagtaattg ttggtgcaga
    60541 tataccaatg tttattggag caatgataat gggaccattt gcaggatggg taattaagaa
    60601 gtttgataaa tttgtagatg gaaagatacc aacaggattt gaaatgttag taaataactt
    60661 ttcaataggt ataataggta tgcttcttgc aatactagga ttttatgcaa ttggaccagc
    60721 aatagtagca gggacagctc ttatagaatc tggagttcaa tttatagtta gcaaaagttt
    60781 attgcctcta gtttcagtat ttatagaacc tggaaaagta ttattcttaa acaatgcaat
    60841 aaatcatggt atattagggc ctataggtat agctgaggca aaagaagcag gtaaatctat
    60901 aatgttctta ctagaaagta accctggacc aggtttagga gttctattag catattggat
    60961 gtttagtaga ggaagtgtaa aacaatcagc accaggagct gtaataatac atttctttgg
    61021 tggtatccat gaaatttact tcccatatat tttaatgaat ccagttttaa tattggctac
    61081 aatggcaggt ggagcagcag gaatattgac tttttcaata ttaggagctg ggcttgtagc
    61141 agcaccatca ccaggaagta tatttgcact tatggcacta gctccaaagg gaggattact
    61201 tccagtatta gcaggagttg cagtggcaac agttgtatca ttcttagtgg cagcaccatt
    61261 tgttaagaga gcttcagcaa atcaaagtga agaagacagt acttctttag aagaagctaa
    61321 agcaaaaatg agtgatatga aatctgcaag taagaactct gagaaaaata ttgaggaaaa
    61381 acagcttgaa gtaaatgaga ttaagaagat tgtatttgca tgtgatgcag gaatgggttc
    61441 gagtgcaatg ggagcttcca gatttaaaaa tagaataaaa aacttagact taaatataga
    61501 aattacaaat tcatctgttg ataatcttcc agatgataca caaatagtag taactcacaa
    61561 tacattagtt gaaagagttg ctaagaataa ttcaagtgtt gagatagttt caataaacaa
    61621 ttttttaaat gacccaaatt tagatacatt gtttaaaaga ttagaatcta aataaaaata
    61681 aaaagtacca ctaattagga gtggataatt tgaaaaaaaa gaagattaca tctaggcaaa
    61741 aaaagataat actaatgata gtagcaaatt caaagaaaaa cattccaata actatttctg
    61801 agattgcagg gactttagag ttaagttcaa gaactgtact tagagatatg tctggaattg
    61861 aaaaatggtt tgatgaaaat gattttaact ttgtaaaaaa accaggagtg ggattgattt
    61921 tagaggaaaa tatagaaaat caaaacttta taattgagtt gttagaagaa gaaaaaatag
    61981 aaaaagaata cagcaaggaa gaaagaaatt taattatatt atcaaagcta ctagtttcta
    62041 acgagccagt aaaatcctat tattttgcaa aaatattaaa ggtatctgaa tgggtactga
    62101 ataatgattt tgccttagca agtaaatggt tggaaagatt tgatattgag cttgttagaa
    62161 aaccagggct cggtgtctac ttaaaaggtc aagaaaaaaa ctttagagag gcatatgtaa
    62221 atcttatata cgattcattc aatgaaaaag aaatactaga tatggtcaga aatataagtg
    62281 aaaatataca aacagataaa gcaatagaaa ttttaagtga aaatagactt ttaaatttaa
    62341 tggacaggtg cataataaga aaagttgaag ctacattaac aaagaagctt tcagatttag
    62401 atgtaaattt agctgatagt gcatatatag ggcttgtagt tcatatttca ttagccttac
    62461 agaggataaa aaatggtgaa aatataacta tggataaaga gtttctaaaa gaattatcta
    62521 taacagaaga gtttaaatta gctaaagaaa tcgtaaaagg tatggaaaca gattttaaca
    62581 tggatatacc agtagatgag gttggatata taactatgca tataagaggt gcaaagcaaa
    62641 ggtcatcttc aaaccataag gctttaaact tagatgatat agaaataatg gaaattacaa
    62701 ataagatgat agatttggcg gaagatgaat ttaaaataag tttaaaaaat gacgagaggt
    62761 tatttaaaga cctagcaaat cacttagggc cttctataaa taggttgaat atgggattag
    62821 aaataagaaa tcctctttta gatgaaataa aaagcaagta ttcatatgcc tatgatgtag
    62881 ttgaaaagat ttctagaatt ataaaagata aactaaatat aaattcaata cctgaatcag
    62941 aaataggata tattgcaatg cactttgcat cagccataga aaaaaatctt atgatgaata
    63001 ctaatataaa tattgttgtg gcatgtccca ctggaatagg tacttcaaga ttcttatcaa
    63061 ctaagattga aaataaattt cctaatttaa atatacttga aaccatatca gctataaaca
    63121 tagatgaaga gtatttaaag gaaaaagatg ttgatttaat agtgtctaca gttgagttaa
    63181 atacaagttt aaattatata tgtgtaggtc catttatgag tttagatgat gaacagataa
    63241 tcaaggaaaa aataaaatct atagctcaaa ataaattaat caatttaaat gcgaaaaatg
    63301 atactaagag taagaataaa gtatatgaac agataacaga aagtatgaat ataggaaaag
    63361 atattcttca atttttagag gaaattagat ttgaaaaatt tgaaagtaaa gatttaagtg
    63421 agcttattga agactcatca aaaatatttg caaaatctag tgaagatata atctctataa
    63481 aagaatcgtt aaaagaaaga ttaaaaattt caattccata tatagaagaa tcaaaaattc
    63541 tattgttaca ttgtatgagt gaaagaatag atattatgaa gttatcaata ataaaactag
    63601 agaatagaat cgtgctagat tcaaatgaag aaatcgacaa tgtagttttt atgttacttc
    63661 ctaaaaattc accaagttat caaagacaaa taatgagtga aataagtggt tcattaatag
    63721 acaatataat ttttactaat aagataaata aattctctat agaagagatg gcattagagg
    63781 taaaagatat agtttttaat ttttatacaa acagattaaa agcatttata gataaataaa
    63841 attaatatta aaaaggaagg ttgatactat gagtaaagta ttgaatgaga ataatatatt
    63901 tttagggtta gatagtgttt caaaggaaga agctataact ttagcaggaa gaaaattagt
    63961 tgaaaatgga tatgtaaaag aagaatatat accagcaatg ttagaaagag aaaaagtaat
    64021 gactacatat atgggaatgg gagttgctat tccacatggt gtaaatgaag caaaaaaaga
    64081 aatattatct tctggaatag ttatattaca attccctaat ggtatagatt ttgatggaga
    64141 aaaagcatat ttattaatag gaatagctgg tgttggagat gaacatttag aaatactatc
    64201 taatatagca gtagttttag atgatgactt aacagaaaga ctaaaaaatt caaatgacaa
    64261 acaagctttt atggaagctt ttgccaacta atcttaggag ggatttaaaa tgaaaaaggc
    64321 aattcagttt ggagcaggaa atattggaag aggttttatt ggaggcttgt tagttaagtc
    64381 gggttatcat gtagtatttg ctgatgtaaa tgaggagata ttaaactcaa taaacaaaga
    64441 taaaaagtat actatacaca taagagatgt agaatgtata gatgaagtaa ttgataatat
    64501 aagtgcggtt tcatctataa aagaagaaat aatagatgag attgtacagg ctgaaataat
    64561 aactacagca gttggacctt tagttttgac taaaatagcc tctacaattg caaaaggtat
    64621 aaaggctaga aaagaaaagg gattaacaag taatctaaat ataatagcat gtgaaaatgc
    64681 aatatacgca agttcttctt taaaagaaga ggtacttaag tatttaaata aggaagaagt
    64741 agaatattta gagatgtatg ttggttttcc aaactgttca gttgatagaa tagttcctcc
    64801 tggtaaaaac gaaaatcctc ttgatgtaac agttgaaaat ttttatgagt ggaatgttga
    64861 aaaacaagga tttaaagggg aaataccaac tatagttggt atgaatttag ctgataatct
    64921 tatggcttat atagaacgta aattgtttac actgaataca ggtcatgcta taacagctta
    64981 tataggatat ttaaaaggat ataagactat agaagagagt ataaaagata aatttatctg
    65041 tgatatagtc aaaagtgcaa tggtagaaag tggagaagga ttgattaaaa aatacaattt
    65101 tgactcagaa gtgcactata aatatattga taaaatttta aatagattta aaaatccata
    65161 tcttaatgat gatgtattaa gagtcggaag ggaaccatta agaaaactaa gtgataaaga
    65221 tagattgatt aaacctttaa tgacagcaaa atcatatgga ttatcagttg ataatttgat
    65281 tcttggaata ggtgcagcgc ttcattataa taatagtgaa gatactcaaa gtgtagaatt
    65341 acaagagttg ataaagtcta ttggagtaaa aaaagccgtt gctaaaatag ctaatataag
    65401 caatgacgaa gaacttttaa acaatatcga aaaaagttat atatttatga aaaatttata
    65461 aatttacttg aaaaaaagta gttctgataa agtaactata atatattatt ctacacagtt
    65521 tgaattattt gttgaataat agagaattat aatatataat taaaaggaat aaattaatat
    65581 atttacctgt atatgtttga taatatggtt caaatgtttc tactaagcta ccattaatag
    65641 cttgactaca ggagtgaaga agatatagtt tatacttatt ttaaattata tattaagtta
    65701 attactttga attttaagct cctgtctatg atatagacag gagctttttt agtattttaa
    65761 tataaaatac ttacaagaat agatagcaaa attagaacaa atataatttt tttattaata
    65821 taattttaga aagggctagg tggaagttca atgaaggctt tacaagaaaa gatattgaga
    65881 gaaggcagtg tttcaggaaa tgatatacta aaagttgata gttttttaaa ccatcaaatt
    65941 gatgtagctt ttttaaatga aataggaaga gaatttaaag agagatttaa aggagaaaag
    66001 gtggataaga tatttacaat agaggcttca ggaatagcta tagcatcaat tgtttcacag
    66061 tattttgata atgcacctgt agtatttgca aaaaaatcag aatctaaaaa tttggataaa
    66121 gatgtatatg aaactaatgt atattcattt actaaggcaa gagagtattc agttaaagtt
    66181 tctaaaaagt acataaacaa aggcgaaaat atattgatag tggatgattt tttggcaaat
    66241 ggaagagctg ctcttggact taaagattta attgagcaag cagaagctaa cttagttgga
    66301 gtaggaattg tcattgaaaa aggatttcaa gctggaggag cacttttaaa ggctaatgat
    66361 gtaagattag agtctttggc agtagttgaa tctatagata atggaactgt aaaatttagg
    66421 taatttatga tattatatac ttgtgtttag cacatatttt aactatgtaa ttatggagga
    66481 ttttttatga gattttttat agacacagcc aatattgaag aaataaaaga agcaaatgat
    66541 ttaggtgtaa tctgtggtgt aactactaat ccgtctctaa tagctaaaga aggtagagat
    66601 tttatagagg tagttaaaga aataagtgaa atagtagatg gaccaataag tgcagaagta
    66661 ataagtttag aacataaagg tatgatagag gaagcagaaa aattatctaa gatacataaa
    66721 aatatagtta taaagatacc tatgacagca gaaggtctaa aagcggtgaa agtactatca
    66781 agtaaaggta taaagactaa tgtaacgctt atattctctg ctggacaagc tcttttagct
    66841 gctagagctg gagctacata tgtaagtcct tttgttggta gattggatga tatatcacaa
    66901 aatggtcttg atttaattga agaaatcgtt gatatattta gtgtaaatag tattgaggct
    66961 caaataatag ttgctagtgt tagaaatcca atacatgttt tacaagctgc tagaatggga
    67021 gcagatatag caacagttcc tcttaaagtt ataaaccaaa tgattaagca tcctttgaca
    67081 gacaaaggaa tagatagctt tatgaaggat tgggaaggtg cttctttaaa attataatta
    67141 taaactacgc tttataagta tattaaagag gttattatgg aaattctaag taataaggct
    67201 aggctatttt gcctagtctt attttggtgt ataatatatt gaaacatatt attgaaatag
    67261 attaattttt taagtgagga ggcgaaaaat ggataaaata ttaagagaga tacaaagaga
    67321 agataaaaaa aatccatata ctgaccaaga acttgctgaa atgttaaatg tagctaggtc
    67381 tgaagtgata tcagttagga aaaaaaataa tattttagat tcgagagaaa gaagaaaaaa
    67441 aatattaata aaagatatat caaaaattgt aagtgaaaat cctcaaatgt ctgaaagaaa
    67501 aataactgaa atattaatag aaaatggata taatatatcg agaagtgcag tttcaaaatt
    67561 attaaaagag gaaaatttaa atcagtcaaa gattgggatt aaggataaag acccagcatc
    67621 atcaggaaag tatgtgaagg tgagtaaagt tgtagaagaa gatggatttg aagaattgat
    67681 aggtataaag ggaagtttga aagaaaaggt aaatctagct aagtcagcaa taatgtatcc
    67741 tcctaatggc cttcatacta taatatatgg agaaacagga gtaggtaaaa gtgaattagc
    67801 tacatgtatg tataaatatg ctataaaaaa caacattaaa gaagagaaca gcccatttat
    67861 agtgtttaac tgtgcagact atgcagaaaa tcctaatcta ttgatagctc aactctttgg
    67921 ggtagtaaaa ggtgcatata caggagcaga tgcaaataga gaaggtcttg tagaacaagc
    67981 taataatgga atattgtttt tagatgaaat tcatagattg cctgctgctg ggcaagaaat
    68041 cttattttca ttaatagata gaggagaatt tagaaggtta ggagaaagta gttctaatag
    68101 aaaggcaaat gttctcataa taagtgctac aacagaaaat ccagattcta atttacttca
    68161 aacatttaga agacgtatac caatggtaat aaatttacct aatatgagtg aaagaccaaa
    68221 atctgaaaga tatgaaataa taataaagtt ttttgaaaga gaagcaaagc gagtaaacaa
    68281 gaattttata ataactaaag aagttatgtg tgcacttatg aattataagt gtactggaaa
    68341 tataggtcag ttaaagagtg atatacaagt aacttgtgct agagctttta gtaaatcgat
    68401 attttctagc gataaagtaa ttatagattt agatagttta agggattata taaaaagtgg
    68461 atattatgat tgtaattgta aaaatgaaaa gtattctgag ttttcagttg aggatatata
    68521 tatagatatt agtgaattgg tgagtggaaa aaatagaatt ttatctgata atgagataag
    68581 cgagatatat aattatgcag aaaaagagct taaggttttg gaaagtaagt gcttttcaga
    68641 agaagagtta aaaaatgcat ttatagaaaa gttagataag aagtttaatg ctattaaaaa
    68701 caataaaaat ttatctgata gaagaagtcg aatagactgg ggaggacaat taaaagagtc
    68761 tacactggag ataatggata aggtaattgt atttattaag gagcagttta agcatgtaaa
    68821 tcaaggtctg tacttggctc tagcaattca tattgagcat gctataggta ggataaaaga
    68881 tggaaaaact ataataaatc cgagtttaga taaaataaaa gcatcaatgc caatggaata
    68941 tgagttgtca agatatataa tgggtatagt agaagatttg acacaagtaa catttccaga
    69001 agatgagctt ggatatttgg cttattatat aaataaattt tgttataatg aggaaagtat
    69061 aaaagataaa gttaaagtag taatagttac gcatggtaaa gttggaattg aaatgtctaa
    69121 agttgtaaat catattttag gtatagaatg tacactaggt atagaaatag cacttacaga
    69181 ttcaccatca gaggggatag agcatgtatt agaagaactt caaaagatag aagctagaaa
    69241 aggtattcta gttctaattg atatgggttc tttggtaatt cttggtgatg aggttgaaaa
    69301 aaggcttgga attagatgta aaactgtaaa tagagtagat acattattgg caatggaagc
    69361 aggaaaactt gcaacaattg aaggaaaaag tttagatggt ataatagctg atttaaagaa
    69421 aaataagaat tatgctatga taaatacaaa taaatttagt tacagaaaaa acgagtatgg
    69481 aaagaaaaat gtaatcatta ctttatgttt gagtggtgta ggtacagctt taaatttaaa
    69541 agagcatata gaaaaacaaa ttaaggaata tgacacttta attgaagtaa agccagttgc
    69601 ttttttaaat aataatttag aagaagagtt aaatgatatt gaatctgaat ataatattat
    69661 tgctatctgt ggaactattg atatagatta taaaaacgtg ccttttattt cttataatga
    69721 ggtacttggt aaaaatggta ttaataaagt attagagcat ttaaatagta aacaaccagc
    69781 tttaaatatt gaaaaccagt tgaataattt aatacatgaa gatttgattt tatacaattt
    69841 tgaaggaatt tcaaaggagt atataattga tactcttgtt tcaaaacttg aagaaggtgg
    69901 atatgttgac tcaaagtata tattaagtgt atataaaaga gaagcaatgg gaagtgttgt
    69961 aatggcctct aaggtagccg tgccacatgg acttccagaa aacgttatga agcctgcaat
    70021 agcaatcgcg aggttgaata aacctatagt atgggacaat aaatttatgg tggatttggt
    70081 ggtactactg gcacttaaag aaaataataa gaaagaaata cgaagcttat tttcaaagat
    70141 taatgaccag catactttag aagttttatt aaatactgaa gataaaaatg aaataaaaga
    70201 acttttaagc taattattag taccgagaag aaagacaaaa aaatttgctt tagtataaaa
    70261 tttaaaacta ctcaattgct aagtagttaa ttactctata taaggctagt tctatgaaat
    70321 ttatttatat gattttatag aattagcttt tttcttggta aataaaatat ataaatttat
    70381 ttatgtaaaa agtaaatttt attggacaat tctataaaaa tttttcctat atttcttata
    70441 aaatatagaa tatataaaaa atatataaaa ataaattaaa ttcataataa ataattttat
    70501 aaaatagttg ttaaacataa aaaaccattt gtaaaaaaca aaaaaatcat ttctctaaca
    70561 aaaaaaacca caaaaaatat aaaaaagtat ggctagttaa gtgattaaca agtaaaaatt
    70621 aaaataaaaa tcaaaaaaaa tttatcaatg aaagtcagct aaaatcctgg aagagagcat
    70681 tatttttggg aaaacatttt cttttgtttc acaaaaaaag ccactttttg gcacacaaca
    70741 tgctttatat aaagtcaaga aaaactaagg tataagacaa aggcaattag gaggtgtaaa
    70801 tatggagttt ataaattttg taagtgataa agttatagac cttaaaatgg attgtaaaac
    70861 gaaagaagat ttctttaaag aaatacataa taaagttttt gatttaggct ttgtaaaaga
    70921 agaatttgga gaaaaaatat tagcaagaga aaatgtattt ccaacaggtt taaatttagg
    70981 tgattatgga gtagcaatac cacatacaga tgcggaatat attaaagagc aatttatatc
    71041 agtctgtact tttaatgaac cagtagtatt tagttctatg gaagaccaag atgaaaaagt
    71101 acctgtaaat ttggctttcg tattaggact taatcaacca cacagtcaat tatctgtatt
    71161 aacagaatta atgggaatta tgcaaaataa agagttagtt gataagttga tgagttctac
    71221 tgataaagaa gaagttttaa agacactaaa gtctttataa aaataaaaaa gtactaaaaa
    71281 taaaaaatat aaaaataaaa attattagga ggaaataaaa atgaaaaaaa tattagtagc
    71341 atgtggagca ggaatagcaa catcaacagt agtttgtgac aaggtagaga gattagttaa
    71401 ggaaaataat atacaagcag aagttataca atgcaaaata gctgaatgtg caacaaagca
    71461 agaaggagca gatttaatag tatcaacaac tatactacca acaacttata atataccagc
    71521 aataaaagca acagcatata taactggagt aaatacagca gcattagata aaaaaatatt
    71581 agatgcttta aaataatcct atcatagata cattgaaata atattttata aaacagaaaa
    71641 aggaggattt ataaatggat aaattattag cagtagtaca atacatttta aatatgggac
    71701 cgacagtaat actaccaata acaattgtag tactaggaat gatatttaga attaagttta
    71761 caaaagcttt aaagtcaggt cttacaattg gtataggatt tgtgggtata aacttagttg
    71821 taaacctatt aacatcaaca ctagggccag cggctcaagg aatggttgaa agattcggac
    71881 ttaatttaac agtaatagat gttggttggc caacaacagc atcagcaaca tgggcttcac
    71941 cagttgcacc aatattaata ccagtttgtt tattagtaaa cttactatta ttatacttca
    72001 ataaaacaaa gatattaaac gttgatatat ggaattattg gcactttata gtagcaggtg
    72061 cagttggata tatagtaaca ggaagttatg tttgggctat attctgtgca atactaatgg
    72121 agttattagt actgtttatt gcagaaaaga cagcaaaaaa tgttcaggag ttttatgatt
    72181 tagaaggtat agcattacca actggttcaa cagcttcatt tgctccactt ggatatttag
    72241 taggtaaatt tgttgaaaaa ataccaggaa taaataaaat acaagcagac ccagactcta
    72301 tacaaaaaag atttggtata tttggagaac caatgatgat ggggattata ctaggtataa
    72361 tacttggagc acttgcggga tatgatgtag caggaatatt caatgtaggt atatcaatgg
    72421 gtgcagtaat gttacttatg cctagaatgg ttagaatatt aatggaaggt ttaattccaa
    72481 tttcagaatc aataagagat ttcttacaag caaaatatgg agacagagaa ctttatatag
    72541 gtctggatgc agcagtagca actggacatc cagcagttat atcaacagct cttatacttg
    72601 ttcctataac tttgttctta gcagttatac taccaggaaa caaagtttta ccatttggag
    72661 acttagcgac aataccattt tatatggcat ttatagtgtg ttttagaaaa ggtaatatag
    72721 ttcaatcagt tataacagga acaatagtaa tagctatatc actttatatg gctacaaact
    72781 ttgcagatgt tcatacacaa ttattacaac aagcaaatat gatgccagaa ggaacaacaa
    72841 tggttacaag tatagataca ggtggaaact tgctaaaatg gggaatattg aaattatctc
    72901 aattagtttc ttcatttgga atattctagt atgtagttaa tagagattac tcttttttag
    72961 taaagtatgc gaaaatttaa catttagcag ctactaaaaa agagtaatat tttttataaa
    73021 tttttaaaaa tacaaaatac aagaggagga gatttatcgt gaaagcagca gtattacatg
    73081 gcacaaatga tatgagattt gaagatatag aaataaaacc atgtgaaagt gatgaagtaa
    73141 aaataaaagt tatggcagca ggaatatgtg ggtcagatcc tccaagagta ttaaaacatt
    73201 ggaaatatcc agttccagct ataccaggac atgagttttc tggagtaatt gctgaagttg
    73261 gtaaggatgt aaaaaatgta aaagttggag atagagtagt tgcaattcct tttatacctt
    73321 gtaatgaatg tgaatattgt aaaagaggat tattttcatt gtgtgatgac catggaatgt
    73381 taggagctaa aagttttgga gcttttgcag agtatgtaaa tataaaagct acaaatgtac
    73441 ttccaatagg agatatgaac tttgaagatg ctgcaatgat agagccacta gcagttgcta
    73501 tgcatggagt acttaatata ggtgttcaag ttggagacac tgtagctgta atgggtagtg
    73561 gaacaatggg gcagttggta atacaaggac ttaaaatagc aggggcagga acaattatag
    73621 cagttgatat atctgataat aaattaagag aatcaaagga attaggggct gatataataa
    73681 ttaatgctaa agatattaac ccagtagaaa aaataaaaga acttactggt ggaaaaggtg
    73741 ttgacatagc tcttgaatgt gcaggttcaa aaataactca agaacaatgt ttacttataa
    73801 ctaaaaagaa aagtaagata ggatttttag ggatagcata ttcagatata actttatcag
    73861 aagaagcatt tgaaaatata tttagaaaag aactagaatt aaaaggtttt tggaactctt
    73921 attctgcacc atttccagga caagaatgga ctaagggaat caatctagtt aatgaaggaa
    73981 agataaaatt aaaagaaatg gtatctcata gattctcact tgaagatact tacaaagcat
    74041 ttgaaatgat aagagataga aaagaagaat ttaacaaaat attaatttta ccacaagggg
    74101 ttgaaaaata atgaaagcag tagttaaaac taaaccaggc tatgataatg tagaagtttt
    74161 agaagtagaa gaaccaaaag ctacaggaga caaggttaaa ataaaagtag aatatagtgg
    74221 tatatgtggt tcagatatac attcatttaa aggtgaatat gcaaatataa aagccccagt
    74281 aacattaggt catgaatttt ctggaattgt tgtagaagta ggagaagatg ttaaaaatat
    74341 aaaagtagga gatagagtta catcagagac tacttttgca acttgtgaga aatgtatata
    74401 ttgtgaaact aaagattata acttatgccc aactagaaaa ggtattggta ctcaagtaaa
    74461 tggaagtttt gctgagtatg tattatcaag agaagaaagc atacatgtac ttcctgaaaa
    74521 tgtatcttta ttatcagcag cccttacaga gccactagct tgttgtgttc atgcagctct
    74581 tgaaaagact actatagaaa gttctgatac agttttaata ataggaccag gaccaattgg
    74641 tttattatta gctcaagttg ttaaatctca aggtgctaca gttataatgt ctggtgttac
    74701 aaaagataag gaaagattag aaatagctaa aaatcttgga gtagatagaa ctgtaaatgt
    74761 aatggaagaa agtttggcag atgtagtgaa tgaaatgact gatggaaatg gagtaaacaa
    74821 aggatttgat tgttctgggt ttatgccagc agttaacgaa gccttaagac tgcttagaaa
    74881 aaaaggtact ttcgtacaag ttggaatctt tgctaaaaaa ttaaatgaaa tggaccaaga
    74941 agcaataatc caaagagagt tacaatatat aggaagcagg tctcaaaagc caagttcttg
    75001 gattacagca ttagatttaa tggcaaatgg gaaagtaaat acagaagctt tagttactag
    75061 aactgttggt ttagacgaat ttaaagaagg tattacagct ttaatgaacg gggaagaaat
    75121 aaaagtagca gtaaaatctt aaaaaaacat ttgtattatt ttaaaaaaaa ttgtaaaatc
    75181 tactgtagga taaaaaaatg taaggtctta aaaaataaca ggaggaagaa agtatgagca
    75241 ctcttagaga tcattctaat aatattagaa aaaacataat aaaaatggtt gcagaagcta
    75301 aaagcggaca tccaggtggt tcattatcaa tagctgatat gttgacagta ttatattttg
    75361 ataagatgaa cgtatgtgca gaaaatccaa aaatggctga tagagataga tttgttctat
    75421 caaaaggtca tgcagcacca gctttatatg ctacattagc agaaaaagga tttttcccag
    75481 aagaagaatt aataacacta agaaaatttg gttctaagtt acaaggtcac ccagacatga
    75541 aaaaagtagc aggaatcgat atgtctactg gttctcttgg tcaagggcta tctgcagcaa
    75601 atggtatggc acttgcagga aaattagata acaaagacta tacagtatat actatattag
    75661 gtgatggaga aatccaagaa ggtcaaatat gggaagctgc aatgacagca tcacattaca
    75721 aattagataa tttaattgca tttgttgact taaatggatt acaaatagat ggttctaatg
    75781 aagaagtaat gaatgtaagt ccagtagatg acaaattcaa atcttttgga tggaatgtaa
    75841 tagtaataaa tggacattct tttgaagaaa taggaaatgc agttgatgaa gctaaaaaag
    75901 ttacaggaaa accaactgta ataatagcta aaacagtaaa aggtaaaggt gtttcattta
    75961 tggaaaataa tgctgcatgg catggaacag ctccaaatgc agaacaagca gagcaagcat
    76021 tgaaagattt agaaggaggt ctataggaat gggaatagca actagagaag cttacggaca
    76081 agtgttaaaa gaacttgcag aaaataaaga tatagtagta ttagatgcag atttaggaaa
    76141 agctacaaaa agtatatcat ttaaagaagt tgccccagat agattttttg acatggggat
    76201 agcagaaggt gacatgattg gtacagcagc aggtcttgct acttgtggaa aaataccttt
    76261 tgcgagtact tttgcaatat ttgcagcagg aagaggctat gagcaaataa gaaactctgt
    76321 agcatatcca aatttaaatg taaaaatagc agctactcat gcaggtgtaa cagtaggtga
    76381 agatggtggt agccatcaag ctatagagga tatatctcta atgagaggta taccaaatat
    76441 ggttgtatta aatccagcag atgctttaga agcaagacaa gctattctta catctattga
    76501 ttataatgga cctgtttata taagattagg tagagctgca actcctgatg taaacagtga
    76561 aaattataaa tttgaaatag gaaaaggaac tgttttaaga gaaggttctg acataacagt
    76621 aatagctaca ggaataatgg tagcaaaagc cttagaagca gcagaagaac ttgctaaaga
    76681 aggtataaat gtagaagttg ttaatatatc tacaataaaa ccattagatg aagcattaat
    76741 aaaagaaact gctaagaaaa ctggaaaagt agttacagca gaggagcaca gtataatagg
    76801 tggtttaggt tcagctgtat gtgaagcttt agcagaaact aaagatgtag tagttagaag
    76861 aattggtgtt aaagatgtat ttggtcaatc aggtacacca gctgatttat taaaacacta
    76921 tggtttaact acagaagata tagtaaaaaa tataaaagag ttgttataga tataaatata
    76981 tctaaataac aaattgattt gacataagtc aattaaagct gtcttaaaaa tagaaagaaa
    77041 tttctacaat gggacagctt tatttttaca atactttatt tttatgataa ttataaaata
    77101 gtctgaaagt aatcaaaaaa attataaaaa gaggtgctat ttaatgaaaa tatctattgg
    77161 atgtgaccat ggtggttatg aattaaagga atatataaag gaaaatttaa taaataaagg
    77221 tatagaagtt gaagatgtgg gtacaaattc aaaagaaagt gtagattttc caatatatgc
    77281 aaaaaaggta agtcaaaatg ttcaaagtaa aaaatctgat ttaggcatac tttgttgtgg
    77341 aacaggaata ggtatgtcta ttgcagcaaa taagtttaaa ggaatcagag cagctgttgt
    77401 ttctgactgt ttttcagcta aggcaactag agaacacaat aatacaaatg tactttgttt
    77461 aggagaaaga gttattggga aaggattagc aatgagaatt gttgaagaat ggttaaattc
    77521 aagttataat ggagaaagac atgcaagaag attacaaatg attgatgata tagaaaaaga
    77581 aaatttataa atatataatt tataacaagg gggagcgtta tgtctattat ttgtgcttca
    77641 ataatgtgtg cagaccaaat gaagttaaaa gaggaattag aagctcttga agaagcaggt
    77701 gtaaaattac ttcattgtga tgttatggat ggaatatttg ttaaaaactt ggctatggga
    77761 ccagagttat taaaatcaat aagtgaaaat acaacaatac ctttagacat acacttagcc
    77821 acagaaactc cagataaata tattgatatg atgtcttata taaagccaaa atatatttct
    77881 tttcatgtag aatcaagtac aaatgtaaaa gctgatatac aaaagttaag aaattatggt
    77941 atagagccag tgttagcaat aagccctcaa acaagtgtgg ataaaataga agaatatata
    78001 agtttagttg agggtatctt agtaatgaca gtaaatccag ggtttgcagg tcaaaagttt
    78061 aatctttctg tattggataa gttggataaa cttacagaga tactaaaaga ttatgataat
    78121 cctccattta tagaggttga tggaaatata aataaggata ctattaaact tatgaatggt
    78181 aaaaaagtag atatatatgt tgttggtact tcagctttat ttaatgataa gcctccaatt
    78241 tcatataaag ataaaataga agaactaaaa gaaagtataa agtaaccatg taataaaatt
    78301 ataatatgtt tctgtttaat agtaaaaatt taggtggaaa caagaaattt tataatattt
    78361 aataaaaatt ttggttgagt aaggagaatt ttttatggga gacctatata aactacaaaa
    78421 tggtactgat attagaggaa tagcgtatga aaatgattct aaagaagtta acctaactgt
    78481 agaagaagta aaaaaaatag ctaaagcgtt tcatatttgg ttaaaagaaa agactaagaa
    78541 agataaagta actgttgcca taggaactga ttctaggata acaggaagcc aatttagaag
    78601 tactgttatt gaaactttaa ctaatgacga ttgtaatgta attgattgtg agattgccac
    78661 aactccagct atgtttatga caactattat ggatggatac aattctgatg gggcgattat
    78721 gattacagca agtcacttac cttattacta taatggttta aagtttttca cagaaagtgg
    78781 aggtttagaa aaaactgata taaaagagat gttggatata gctgttaaaa atgatagtgt
    78841 agactatgag gaagtaaata aaaaaggtga agttatagta aaaaatttaa tagaagatta
    78901 ttctaattta ttgatagata aaattagaaa aggtgtaaat tcaagtaaaa attatgaaaa
    78961 gcctttttct gggcttaaga tattggttga tgcaggaaat ggggctggtg gattctttgc
    79021 tgaaaaagtt ttacacatac tgggagcaga tacgacaggt agtcagtttt tgaacccaga
    79081 tggtatgttc ccaaatcata tacctaatcc cgaaaacaaa gaagcaatgg aaagcatatg
    79141 taaagctgtg ttagataata agagcgacct aggaataatc tttgatacag atgtagacag
    79201 agctgctatt gtaggtaaaa atggcaaacc aataaataaa aatgctctta tagctgttat
    79261 atcatcaata gtattagaag aacatccaaa aacagctata gtaacagatt cgattacttc
    79321 tgaaggactt gctaaattta taaatgaatt acaaggaaga catcatagat ttaaaagagg
    79381 atataaaaat gtaataaatg aagctataag attgaatagt gaaggtgaag agtgccattt
    79441 agctatagaa acgtctggac atgctgcttt aaaagaaaat tatttcttag atgatggggc
    79501 atatttaata gctaaaattt taataaaagt agcaaagcta tccttggaag gaaagactat
    79561 agaagaattg atagaaaacc ttgaagaagc tcaagaagag aaagaagtta gaataggcat
    79621 taataaagaa gattttagac catatgcaga ggatatatta aaagatttag attctcatgt
    79681 caagagtatt gatggatggt ctgtagcacc aaataatttt gaaggcataa gagttaattg
    79741 tgatgaatca aatggagatg gatggttttt acttagaata tcactacatg aaccattatt
    79801 agctttaaat attgaatcaa ataaaattgg cggagcagaa caaatttatt ctaagttaaa
    79861 acttttctta gaaaaatatg atttaaaagg tctttagggt aaatagaaag aatatattta
    79921 tattgaagaa taaatgtaaa tttgtaccta agattacaaa tattacaaaa ttgtaatctt
    79981 aggtaacaga gatgtaactg attatggaaa cactatgtga tattatagat acagagagat
    80041 gaaatatgtg atgaattata gagaaatata atttaaaatg tattaatatc acaccaaaaa
    80101 ggtataatca aaaaatatgt aaatataaac cccaacattt agaagaagac ctctaaggag
    80161 gtttttttct tgtttaaata acttaaaata tatttttata tcaatatatc aattaactct
    80221 tctaaaagta agcattacct taaataaatc agcatctata attatttcca tgtgtgcatt
    80281 ttctaattca attatatttt gagcaattga taaaccaaga ccagagccat ctgtttttct
    80341 agatatatca ccccttctaa atctttctat taactcttct ggctttagat ttagtttatc
    80401 atttgaaata tttttaaacg ttaatattat attttcttcc tttataaaca tatctatgta
    80461 gaccctagtg ttaggcatag agtattttag tatattgcaa attagattct caaaaactct
    80521 ccaagttttt ttaccatcta tcatggtaaa aacagcatat tcaggtgttt ctattataaa
    80581 atctaaactg ctattttgaa ttttgtcttc aaactctaca atactttgaa ttaaaagttc
    80641 tcttatatcg gtttttgtta tattaaattc tacatctcca ctacttagct tagatgcttc
    80701 aaatatgtca tctattaata attttaatct ttgtgatttt ttatctaaaa tatttatata
    80761 gtcatttata gtctctctgt caaagtcatt attttttaac atatcaacat agcttaatat
    80821 agatgtaagt ggagttttta agtcatgaga tacgtttgtg ataagctctg ccttcatcct
    80881 ttcatttttt atattagcat ctacagcagt ttcaagacca cctgttatat tatttatact
    80941 tttggctaaa gtagatattt catcatctcc tataacttct aatttatact ttaaattgcc
    81001 attttctata ttttttatat tttttgatat gttatttatg taattaaact taacagataa
    81061 aaagttgtat atataaaaat gaaaaactgt gtttacaagt gtaaataaaa ttactatagc
    81121 tattgcctca gcataatata tatacataaa gaatatcaaa acaagatatt ggataatagc
    81181 ttgtacaact atagatatta aaaatactat agctaatttt ttatttatag tttttttatt
    81241 atacatatta agcaagtttg aaaaaaatac at
//
LOCUS       DAMJWC010000009        73541 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMJWC010000009 DAMJWC010000000
VERSION     DAMJWC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73541
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.009"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            99..728
                     /locus_tag="PC503_000781"
     CDS             99..728
                     /locus_tag="PC503_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF2526795.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            796..1629
                     /locus_tag="PC503_000782"
     CDS             796..1629
                     /locus_tag="PC503_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF2526796.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(1725..2513)
                     /locus_tag="PC503_000783"
     CDS             complement(1725..2513)
                     /locus_tag="PC503_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526797.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVSYIARKSTVLKKSK"
     gene            complement(2514..3386)
                     /locus_tag="PC503_000784"
     CDS             complement(2514..3386)
                     /locus_tag="PC503_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2526798.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLIDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(3401..5110)
                     /locus_tag="PC503_000785"
     CDS             complement(3401..5110)
                     /locus_tag="PC503_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526799.1"
                     /translation="MSSIKAISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKINSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(5257..5838)
                     /locus_tag="PC503_000786"
     CDS             complement(5257..5838)
                     /locus_tag="PC503_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2526800.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            complement(5897..6037)
                     /locus_tag="PC503_000787"
     CDS             complement(5897..6037)
                     /locus_tag="PC503_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2526801.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(6049..7365)
                     /locus_tag="PC503_000788"
     CDS             complement(6049..7365)
                     /locus_tag="PC503_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2526802.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(7359..8069)
                     /locus_tag="PC503_000789"
     CDS             complement(7359..8069)
                     /locus_tag="PC503_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526803.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(8508..9083)
                     /locus_tag="PC503_000790"
     CDS             complement(8508..9083)
                     /locus_tag="PC503_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF2526804.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(9376..9654)
                     /locus_tag="PC503_000791"
     CDS             complement(9376..9654)
                     /locus_tag="PC503_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526805.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(9963..10724)
                     /locus_tag="PC503_000792"
     CDS             complement(9963..10724)
                     /locus_tag="PC503_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2526806.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(10893..12968)
                     /gene="bclA3"
                     /locus_tag="PC503_000793"
     CDS             complement(10893..12968)
                     /gene="bclA3"
                     /locus_tag="PC503_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF2526807.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAVGATGIGIT
                     GPTGPTGATGADGATGVTGPTGATGATGADGVTGPTGATGATGFGVTGPTGPTGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGA
                     TGATGATGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDL
                     TNAAGTLTNFAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTA
                     VPGATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAG
                     YASAGIAIN"
     gene            complement(13035..14111)
                     /locus_tag="PC503_000794"
     CDS             complement(13035..14111)
                     /locus_tag="PC503_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2526808.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTDGGFKSDDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(14423..15007)
                     /gene="clpP"
                     /locus_tag="PC503_000795"
     CDS             complement(14423..15007)
                     /gene="clpP"
                     /locus_tag="PC503_000795"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2526809.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(15004..15462)
                     /locus_tag="PC503_000796"
     CDS             complement(15004..15462)
                     /locus_tag="PC503_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526810.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(15685..17100)
                     /locus_tag="PC503_000797"
     CDS             complement(15685..17100)
                     /locus_tag="PC503_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2526811.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            17215..17883
                     /locus_tag="PC503_000798"
     CDS             17215..17883
                     /locus_tag="PC503_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526812.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(18059..18577)
                     /locus_tag="PC503_000799"
     CDS             complement(18059..18577)
                     /locus_tag="PC503_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2526813.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            18729..19052
                     /locus_tag="PC503_000800"
     CDS             18729..19052
                     /locus_tag="PC503_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2526814.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(19057..19641)
                     /locus_tag="PC503_000801"
     CDS             complement(19057..19641)
                     /locus_tag="PC503_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF2526815.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(19690..20145)
                     /locus_tag="PC503_000802"
     CDS             complement(19690..20145)
                     /locus_tag="PC503_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2526816.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            21027..22565
                     /locus_tag="PC503_000803"
     CDS             21027..22565
                     /locus_tag="PC503_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2526817.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(22837..23550)
                     /locus_tag="PC503_000804"
     CDS             complement(22837..23550)
                     /locus_tag="PC503_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526818.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(23998..25377)
                     /locus_tag="PC503_000805"
     CDS             complement(23998..25377)
                     /locus_tag="PC503_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2526819.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(25662..26456)
                     /locus_tag="PC503_000806"
     CDS             complement(25662..26456)
                     /locus_tag="PC503_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2526820.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(26453..27316)
                     /locus_tag="PC503_000807"
     CDS             complement(26453..27316)
                     /locus_tag="PC503_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2526821.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(27294..28289)
                     /locus_tag="PC503_000808"
     CDS             complement(27294..28289)
                     /locus_tag="PC503_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2526822.1"
                     /translation="MSIIELNELTKAYRRFEKKAGFMGSVKSLFNRKYTEKTAILSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            28992..29948
                     /locus_tag="PC503_000809"
     CDS             28992..29948
                     /locus_tag="PC503_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2526823.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(30341..31231)
                     /locus_tag="PC503_000810"
     CDS             complement(30341..31231)
                     /locus_tag="PC503_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526824.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(31409..32107)
                     /locus_tag="PC503_000811"
     CDS             complement(31409..32107)
                     /locus_tag="PC503_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526825.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(32643..33710)
                     /gene="rsgA"
                     /locus_tag="PC503_000812"
     CDS             complement(32643..33710)
                     /gene="rsgA"
                     /locus_tag="PC503_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2526826.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(33707..34108)
                     /locus_tag="PC503_000813"
     CDS             complement(33707..34108)
                     /locus_tag="PC503_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF2526827.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      34905..35001
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            35055..35231
                     /locus_tag="PC503_000814"
     CDS             35055..35231
                     /locus_tag="PC503_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526828.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            35641..36279
                     /locus_tag="PC503_000815"
     CDS             35641..36279
                     /locus_tag="PC503_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526829.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(36752..38110)
                     /gene="rlmD"
                     /locus_tag="PC503_000816"
     CDS             complement(36752..38110)
                     /gene="rlmD"
                     /locus_tag="PC503_000816"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2526830.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(38285..40045)
                     /gene="pyk"
                     /locus_tag="PC503_000817"
     CDS             complement(38285..40045)
                     /gene="pyk"
                     /locus_tag="PC503_000817"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF2526831.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(40097..41056)
                     /gene="pfkA"
                     /locus_tag="PC503_000818"
     CDS             complement(40097..41056)
                     /gene="pfkA"
                     /locus_tag="PC503_000818"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2526832.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(41265..44834)
                     /locus_tag="PC503_000819"
     CDS             complement(41265..44834)
                     /locus_tag="PC503_000819"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF2526833.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(44991..45938)
                     /gene="whiA"
                     /locus_tag="PC503_000820"
     CDS             complement(44991..45938)
                     /gene="whiA"
                     /locus_tag="PC503_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF2526834.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(45955..46380)
                     /locus_tag="PC503_000821"
     CDS             complement(45955..46380)
                     /locus_tag="PC503_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2526835.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(46449..47555)
                     /locus_tag="PC503_000822"
     CDS             complement(46449..47555)
                     /locus_tag="PC503_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF2526836.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(47567..48424)
                     /gene="rapZ"
                     /locus_tag="PC503_000823"
     CDS             complement(47567..48424)
                     /gene="rapZ"
                     /locus_tag="PC503_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF2526837.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(48455..49168)
                     /locus_tag="PC503_000824"
     CDS             complement(48455..49168)
                     /locus_tag="PC503_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2526838.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(49172..50086)
                     /gene="murB"
                     /locus_tag="PC503_000825"
     CDS             complement(49172..50086)
                     /gene="murB"
                     /locus_tag="PC503_000825"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF2526839.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(50359..51129)
                     /locus_tag="PC503_000826"
     CDS             complement(50359..51129)
                     /locus_tag="PC503_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2526840.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            51447..52928
                     /gene="cls"
                     /locus_tag="PC503_000827"
     CDS             51447..52928
                     /gene="cls"
                     /locus_tag="PC503_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2526841.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            53246..53743
                     /locus_tag="PC503_000828"
     CDS             53246..53743
                     /locus_tag="PC503_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF2526842.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            53760..55646
                     /locus_tag="PC503_000829"
     CDS             53760..55646
                     /locus_tag="PC503_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF2526843.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            55669..57450
                     /locus_tag="PC503_000830"
     CDS             55669..57450
                     /locus_tag="PC503_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2526844.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(57590..59386)
                     /locus_tag="PC503_000831"
     CDS             complement(57590..59386)
                     /locus_tag="PC503_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF2526845.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENIILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(59598..60527)
                     /locus_tag="PC503_000832"
     CDS             complement(59598..60527)
                     /locus_tag="PC503_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF2526846.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(60527..62344)
                     /gene="uvrC"
                     /locus_tag="PC503_000833"
     CDS             complement(60527..62344)
                     /gene="uvrC"
                     /locus_tag="PC503_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF2526847.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(62603..65428)
                     /gene="uvrA"
                     /locus_tag="PC503_000834"
     CDS             complement(62603..65428)
                     /gene="uvrA"
                     /locus_tag="PC503_000834"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2526848.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(65447..67417)
                     /gene="uvrB"
                     /locus_tag="PC503_000835"
     CDS             complement(65447..67417)
                     /gene="uvrB"
                     /locus_tag="PC503_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF2526849.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(67604..68866)
                     /locus_tag="PC503_000836"
     CDS             complement(67604..68866)
                     /locus_tag="PC503_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF2526850.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(68929..70233)
                     /locus_tag="PC503_000837"
     CDS             complement(68929..70233)
                     /locus_tag="PC503_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2526851.1"
                     /translation="MKLKRKLATGLAITLLLCSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(70264..71124)
                     /locus_tag="PC503_000838"
     CDS             complement(70264..71124)
                     /locus_tag="PC503_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2526852.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(71168..72037)
                     /locus_tag="PC503_000839"
     CDS             complement(71168..72037)
                     /locus_tag="PC503_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2526853.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(72021..73091)
                     /locus_tag="PC503_000840"
     CDS             complement(72021..73091)
                     /locus_tag="PC503_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526854.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        24103 a        12434 c         8767 g        28237 t
ORIGIN      
        1 caatttatta ttgtaatatt ttgaatatat aataaaatta ataataagaa aactttttat
       61 aaatatactt ttaattgttt aaattggagg aaaaaattat ggatgaaaag ataacaaaaa
      121 ataattataa tgttccattt gactatgttc gaaaaaaact caaagaatta gaccctcata
      181 caattagtaa tttaagtaat atacctttca ataatgattt aaatagattc acactcaatt
      241 tttttgatag acaatatatt atagactatc caagtggaga agtttggaat agtaatggta
      301 gcctttgcaa taactttgag cttaaaatct tgatagttag atatttaatc aatgctaaag
      361 gtattcctag aactaataaa tatgtaactt ttaaagaaat accaggaggc aatgtttatt
      421 atccaaattt tttaaacagg actctatata ggctttcaga agtttttaca tctcaaatag
      481 acaaatataa gttagttatg gagaaaattg gagctgaaaa agtaaacatg ggagatttag
      541 cttataggtt tacatatatg ggtaatacat ctatggtatt tatactttgg tttggagatg
      601 atgaatttcc tccaaattca aatatattat ttgattctaa tatagtttat tacttcaatg
      661 cagaagattt agcagttgtt cctgatacag ctataaatgc aattttaaat aaaataaatc
      721 aattataaat ataaataata ttataataaa gtttttgata gatttaatag aatataatat
      781 gaaatggagt aaaaaatgaa tgtagaaaat caatctttat cagatattga aataatatta
      841 tcacacaggt atgataatgg tgcagactat tggactacac ctgataagcg tttaataaaa
      901 ggttctcctt tctctactct tgatagtgta ctttatctat tagaattagg tgtgaaccct
      961 gatgatactt tacttaaaga atgtgctgac ttgatattta gcacatggcg agaagatgga
     1021 cgtttcaaac tatatccaaa tggaggtatt tacccttgtc atactgcaaa tgctgctaac
     1081 gtactctgtc atatgggata tgcatctgac attagaatgc aaaaaacgtt tcaacatttt
     1141 ttagatacac agtatactga tggtgggtgg cgttgcaata aatttagttt tggtcgaggt
     1201 ccagaaactg aatactcaaa tccactacca actcttaata tattaaatgc attccgtttt
     1261 agtaattatc taaataaaga atcaaaactt gacaaagctg tagattttct acttgaccat
     1321 tggactatta aaaaaccaat cggcccttgt cactatggaa ttggaacctt atttatgcaa
     1381 gttgaatatc ctttccgtaa ttataaccta ttcctttatg tctacgtttt atcattttat
     1441 aattgtgcaa aaaaggataa tagattttta gaagcattga agatacttga atctaaaatg
     1501 ataggtaata aaattgtcgt tgaacgtgta gttccaaaac tatctaaatt atctttttgt
     1561 aaaaaaggcg agtcaagtga aatagccaca acacactatt acgaaatatt aaaaaaccta
     1621 gaaaaataat agttatatag ataaaacata ttaaaaaata gtggctttaa attttttaaa
     1681 gtcactattc tatataaata taacattata aaaaatatat taaactattt actctttttt
     1741 aaaaccgttg attttcttgc tatataagaa actattatta tagaaataac tactagagaa
     1801 cctctattta taaagaaata attctttaat tcattaaatc taacatctat attgttaggc
     1861 atataaaaca tcttttgaat ataaaatcca tttacattaa tcatactaac aaatgggtac
     1921 atatgtaaaa taaaaaatat atcagcaaat gtatatgtaa ttaatattgc tattgttgta
     1981 aatctatttt ttgttaatgt taatatcatt agtggaaatg ttgtatacca taataatgta
     2041 ggaaatgtct ttaaaaacac atctattggc tttacactat aaacaaaatc tattttgtct
     2101 atgttaaaac ctttcactga cgtaaatgta tatactattg taattgaaat taataataat
     2161 acagtatata tagctaatat aacacaccat ctaaatacta taaattgatt atattttttt
     2221 ttattatata aagtaagtat ctcatttata ttacccgaat aatcttttga aaacacataa
     2281 attattgtga ttgctgacat tattggtata aaaacatctg atatctttat aattcctaac
     2341 catcctgcta tagaatatgt atccattata ggtacatcat tataaaatat taactcatta
     2401 taatctaata tgcctgtaat aaatatgcat aagatagaaa taattacaaa tattaacaca
     2461 tgtttaagct ctattttttt aagctcaaat tttattaact ccaatataca catttatttt
     2521 aactccttat gtaaaaagtt tatataagca tcttgtaaag ttgtatctat ccttaagcta
     2581 tctttaagtt tctctgtatt tttacctata tactttactt gcacaccatc tttaactctc
     2641 ctataatcaa taatatcaat attacgttct aaatattcaa attcatcatt agaaactact
     2701 accgaataca cctcaaccat atcaataaac ttattaattg taccatcata taatattttg
     2761 ccttgattta atataattaa tttgtcacag ttaaattgta tgtcttctac tatgtgagtt
     2821 gaaattaata ctatagaatt tttacttatt tctggtaaca atcttctaaa ttcattcctt
     2881 tgctctggat caagaccaac tgtaggttcg tccataacta ttaacttaga atcacctatt
     2941 aaagcctgtg ctatacctag tcgtctcttt acaccacctg agtatgtacc tattttttta
     3001 tttataaact tgtccagatt aacttttgat actacttttt gtatatgttt ctttaaatca
     3061 ttcttagata cacctctcat tttagctaca aattctaagt attcttgccc atttatatta
     3121 ttatacatat caaaatcttg aggtacatat cctacatttg ccttgatttt ctcattgttt
     3181 ttgctatact ttatattatt taattctatc tctccaattg aagtttcata aagagtcact
     3241 aataacctca ttaatgttga ttttccagca ccattaggac ctaataatgc aactactcca
     3301 tctattaggg ttaaatttat attatccaaa gcttttttat ttttgtaatt aaaatttaga
     3361 tttcttattt ctaacttgtt tatcatatta acctccttta ttatttatct attataagga
     3421 tatttcctga aagccaatga taaatagtta tgctaatttt ctctcccttt gagtcttcat
     3481 ataaaaattc attgctaggt aagtcagcaa ctaatatcat attaattttt tttcttttta
     3541 ttgattccat aacattatct acttcatcta catatttttt agcatctaca gatgctttgc
     3601 tatcacctaa tatttcattt cttgtttcaa ttaaaaattt aattttttcc tctatatcca
     3661 tatttacatt actatctgat ggatagatta tttttatatc atcttttacc tcttctttaa
     3721 actcacctgc atatattgca atatcatttg actttccttc aaatatataa tcttttttta
     3781 aaaaattact agtcttattc agtaaaggta aatttgaata gacattattt ttagaactta
     3841 aatttatttt ataagccata caacttgatt gatttacttt tgggtaccac gctaaagaac
     3901 ctggtggaag cataatatca tctttagtag ctatatattt attttgattc caagatgtca
     3961 acacattaat atagccttca tactctatat ctaatgtcac ctcgtcatta ggctctaaac
     4021 tttcctttaa attaacttca attaaatcct tttttttgtt aaattttata ttttccgaat
     4081 ttatttttat atattttata tcaaatattt catctaaaat catattaata tttgttaact
     4141 cttcatttga tgtgtttaat aaaacaattc tatcttttat atttgacttg cttttaaagt
     4201 caatcttcat atcatgcgat tttattttaa tatcactaat attagatttc tttaaatact
     4261 ctccataact acgctcctca tctctatatg ttgacatatc tattgatata taatttaatc
     4321 caataaataa aatactgtac actactataa ctattaatga tttaatctgt ttctttctaa
     4381 tatcatttaa tatcagatat gctactatta ttaaagtaat tgcaaatagt gtaggtataa
     4441 tcttatctat aacatatgct gaattattaa ctttccctac aaaatcagaa tagtaagcat
     4501 atgattgatc ttcaaatatg ttaagtgatt taaataatgc tttaaaaaat ggttctttaa
     4561 tatcaataac tctatccaac atattagttg atgttaaata taaaaatact gatgataagg
     4621 taatctttag tattaaatta tttataataa ctgaaataaa tgatatcact atagataaaa
     4681 tagtaagtgg taaaaaccat tcaaatatca atataaatat agttgattta atcgttacaa
     4741 ttgacaatgt tcttattaaa cttgagtatg ctatagcata tataattggt atgcaacaaa
     4801 atataaagtt gtttctagtt acagcaacag aaatacctaa aaaataatca aaattatttc
     4861 tacataatat ttttacagta tcataacttt ttctcatata aaaaattaca tttaacatgg
     4921 ttaaaatact aattgtcata caagtatata cactcaagga taagtaatca ttaaatgaaa
     4981 ttcctctatt ggatatatgt gtccatcgtt gtatgagatg gtaatttata ataataattg
     5041 ttattgcaaa taaaatattt tttctaatta ttttggttat aaagtctgat atagccttaa
     5101 tactactcat atttatgccc ctcctagcca gtcttttgat acaacctaca atagattcaa
     5161 ctatatttaa taagttcaaa tacttacctt gacattattt ttttaaagtt aatattaatt
     5221 agtgaagtta attaatttag aaaatgtttt ataatcttac tgatcactat taaccttcat
     5281 tccaatatat attaatatag caatccaata tatagaaatt attgcataaa tcacatattg
     5341 ctgaaaaata ttaagtattt tacataaaat aattaaacat attattacga atagtatttt
     5401 ttgcacagtc tttctataat gctttttctc actttcacta agaggtttgt ttctatgttc
     5461 taaaggagct aacttgtaaa ttgttagtat actaataatc attaataata ctaataaata
     5521 cttatattta tttatatcta tattattagc tgaaaaaata gttatcaaat aaataactgc
     5581 aaatgttaat gtacactctt tataattcct agcatgataa cctcctgtga actgtcttaa
     5641 agtgcaataa caacttaaaa atataactgt atgtataaat ctatcaaaaa taattcctat
     5701 aaataatgct accaaaatat taactatgaa ataaatcaaa gtttcaaatc catatctata
     5761 tatttcaaaa tcttcacttt ctacaatctc attattaact aatatattgg caaatttata
     5821 tgataatctt ttaaacatat ttcctcctca acatgtaaaa cctctccttt aataagaaga
     5881 ggtcctttta ttaatgttat ttttttagtt tttgtaaagc ttgtggctct tttgcctgat
     5941 gtgctaccca agaacttgca ctgtttgctg ataatacagc tatcccaaaa cttaatgctg
     6001 agatgttttt aagtaagttt aacgctattt ttttcatttt gtactctcct aactttttat
     6061 tggtatcatt atttttaata taaactcatt atctgagtaa ttaactattg tttcaccacc
     6121 atatttattt actatatatt taatactagc aagtcctatt ccatgtatct tatcatcatc
     6181 cttactagtt tgaatacgtt tatcaataag tttaatatca tttaccttag tatttataaa
     6241 ttttattatt gcaaatttat ttatatatgt agctttaact tctattcttt tttctatctc
     6301 attatttata tccatacatg cttcaattgc attatctagt gaatttgcaa atattgaaca
     6361 tatatcatta tttttaataa agtttaattt agatatattt atgttatctt caatttgaat
     6421 atcatacttt ttacaaatac ttattttttc tgctaaaatt aaatctaatg ttttatttcc
     6481 agtattttta aaatgttcaa attcacttat ctgaaactct aagttattta tatatgatat
     6541 aatttcttct ttagtgtcat aattttttat acaaatcata tggtttttca agtcatgata
     6601 aacatatttt aatctatcat gaacttcgtt tatattttca taattcctgt agtttgtttt
     6661 tattctttca tttataagtt catactctag atttaattta tcgtcttgta caattttccc
     6721 tattactatt aaaagtatta tacttgatga taaaatcaat aaaattgcaa atataaatat
     6781 aaataagttt tctgtagtaa ttgtattgac tcttaaatta tattcaaata taagtaataa
     6841 gctaactata ttagataata taggtattcc tattagtatc atatctttag gtttaaaatc
     6901 taaagataat ttaaaatact taaacaatat aaaacctata aataaaaata cctttgacat
     6961 aataatagct tgtattctaa ataagttttc atgttgtgtt atgttaatat tatttaattt
     7021 atttataaat actactagac ctactgcaga accttcagca accattaatc ctagccaaaa
     7081 caataaacta actattatac ttttatagat tttatcttca tatgatgtta tataaaatga
     7141 tattcctatt accatacata gaagaatctt aatatttgga aacactttaa ctacatttat
     7201 gtatgccata aatataatta taattattgt tgtaaatata tatcttatat tagatatttt
     7261 cctctttcca actaagtgga ttactaaaaa aaatataatc caatctatag tacctgaaac
     7321 taaattaata atattccaaa atcctacact taaatttgtt agcatactat gtcccctaat
     7381 atattagtta tcgcaagctt caagccttta accctatatt tacttattgg aatacttttt
     7441 ccatctacta taacagtact tccactcatt gattctacta attttaagtt aactatatag
     7501 ctattatgac atctaaaaaa tccatattca tttaatatct tttctatttt agatatactc
     7561 attttagtaa tatacatatc atcatgtgta taaatcaata tattcggtct atctgtttct
     7621 atataagtaa tagaatctat tttaattcgg tctacataat tttttacatt tatagttaag
     7681 taattatttc tctttttcat catctcattt atacaaggta atacactttt agaaattttt
     7741 tctttattta ttggctttag tatatatctg tatgctttta cctcataacc ttcttgcata
     7801 aactctacaa atgaagtaac aaatattatt tctaacttat gatcaaactc tcttatcttc
     7861 ctagcagtat ccataccatt tattgttttc atttgtatgt ccataattaa tatgtctaaa
     7921 tctttaggat agttatttag taactcttct cctgctgaaa attcatatat gttataattt
     7981 ataggatatg aacttaatat ttcacttaat atatctttta tttttattcg ataatgtagt
     8041 tcatcatcac atattcctat attaatcaca attcttaaac atcctttctt atatattttt
     8101 aataaaaata tataaatttc tattcatttt acatatttta acatacttct gtagtaaata
     8161 gctatttaga ttttaatttt agctttttgg acattaagta ttactttttg gatttgcaat
     8221 ctattttgat tttcattata atacaatttt ttaatatata ttaaatatat ttagggattt
     8281 taataaaata ttcctcgaaa agtttttaat atctagtttt tgttaaataa aaagtatgca
     8341 ccttcctttt tatagtaata ttttaattat cgctataatt ttgaagaata cacactatat
     8401 tttaaatatt aatataaaac atattaaaaa atagtggctt taaatttttt aaagccacta
     8461 tttttttaaa tgatgttcct gaaaatatat taagttagtt attctaatca atttgaagac
     8521 ttttgcttct ccttgcctat atctaacata atttcataat ttaatttacc tttctttaaa
     8581 tcaactcctg agttacttct aataatccca caatccaaca tttcgtcaaa taccttccta
     8641 gataaaccta gtttctcacg taataatgtt gataccttta actgacatgg atatttacta
     8701 ataatatgaa cttgtgtaag gtcattaata ttaatttctt gtcctactat tttatactct
     8761 ggaataccaa cttctgctcc atttctatgt aaaagttcca tattcatagc atattgctta
     8821 acaagattat aatcgtttgt atggaattgt tctagtattt ctggatttaa gctttttgga
     8881 ttaacacgag aatatatagt tgagttccat gttgaatcac aatttgaaca cttgtatatt
     8941 aaccatatat ccaaatattt atgttgagca ttaaccctaa ataaacctga acaaatatat
     9001 tcagtctttt ttccacattt tttacaatac ctaattacag gtaactggga gatatattcc
     9061 acctcccaag taattttttt cataaatgca atttcctttc tataagatta ctaaattaat
     9121 agaaagttat gaaaaggtgg aatataatca agtatttttt tcaaaacaag acctcctaat
     9181 tttaataaat tttaatttca aacatataaa aagctactac ttcttattag atactttaca
     9241 accagctttg ttagctactg tataagttat tgaaattact taaattatat catccactta
     9301 aaagaaacta tacctcaaac acttttatca aaagaaaatg agccagtata attataaaac
     9361 tatactggct catccttaga tatcttttct tttttcttgt aatacaattc tttggatact
     9421 tttcaaagat aaataatact tttccgataa atattgcaaa tcatatccaa cttgatagtc
     9481 ttcgtaaatc tgcatatttc taattgacaa ctcctcacga gtaggtgtat tacttcccca
     9541 ttctttttta ttattagatt ttctaggaat atagatacat tcaccatcta catattcctg
     9601 tattaattca agtaattctt ctggtaatat atgtattgct tttttatagc tcattttgct
     9661 ctcctattaa atagtaattt ttcattagga atagcaaagg gctatttata tattaaattt
     9721 catagttgca atagcccttg ctatgcaaaa ataaagatta aatcaaacat aaaatctcaa
     9781 ccctccttat atatcacagc gatacatata agtctatcaa cagtataact ggttgtcaat
     9841 caacacaaat tatttatcca ttttttaaac acatttattt agtttttata ttatatttat
     9901 tttgataact aaaatttttt cattataaac tatctttaaa attattagtc aacttaaatc
     9961 cattatcttg atgggtttat tactgaacaa ggaactccaa ctatacactt tccacaaata
    10021 tcacatccac ctatataagt gtattttttt tcatttatca tacacatttc ataacactta
    10081 ttcctattaa atccatcttc ttttaaagct tctttcacgc atttgttgac acattttttg
    10141 caactattat tatgtttata caagcagtat tcattttctg gtcttttagt tggctctaat
    10201 tctaaacttg tgattatgct tcctattctt ccacaacacc ctttttctgt aataagcata
    10261 ttatttaaac caaaagttcc aagacctgct atgaatgcta catgtctttg tgaccagtca
    10321 cttaccaatt tttcactgtc aaaattatac gacccaggaa tagcatatga attagccccc
    10381 atcttctcta gttcttcaca taagaaatca tttaaatttg aaatcaacat attagtttct
    10441 atgtacgctc ttgcccatat ttcagaacat tcaaaccctc caatattact attatttaca
    10501 ctttcatcaa aaggtataaa atatgtaatt atagtttttc cattttccag aaaatctttt
    10561 ggcatagcat gagatgttcc tacaacactt tttagcttct gaaacatatc atcttcagca
    10621 gatgcataag caaacaaaag ttcttgccac tttgtagtta tattatttga tttatgataa
    10681 ttttttacaa agttgttcat tgatatttca atcttatttt tcatagtatc acccctagat
    10741 aattctatat ttccaattta atgttattat tttatattat ataatagtat tttataatat
    10801 gcgcactaat taatattaaa actatgttca tcaatcattc ttaaaaaagc tcctaatatc
    10861 aatacgatat tagaagcctt ttcttatcta atctaattta ttgcaattcc tgcacttgca
    10921 tatcctgcta cagtattaac taatgaaaga cctgaagctg ttgcagtaaa tactagtaag
    10981 aatcgagttt ctgctgttgc tgctatattt aatcctgtta caattccact agaaattgaa
    11041 ccaactgata atattcctgt aagtggtgga gctagtgtaa ctgtcgctcc tggtacagct
    11101 gtaaatgagt tatttggtgc agtagattgg taaagtgttg ctgtaattgt aactgttgag
    11161 ccaacaagtg aaagtgctgc tgttgtactg aagtatgctg aaatagatgt tattgttcca
    11221 gctcttggca ttgaaaatgc aaagttagtc aatgttcctg ctgcgtttgt aaggtctatt
    11281 actccaccaa ctatacttaa tcctggagct gaactaccaa agccaacaaa acctggtgta
    11341 cctactaatc ctccagctat agttgtaagt gatagtggta tacctgatgc aaaaggtatt
    11401 attgcactag cacctgttgg acctgttgct cctgttgctc ctgttgctcc tgttggacct
    11461 gttgctccgg tcgctccggt tgctccggtt gctcctgttg gacctactaa tccatctgcc
    11521 cctgttggac ctgttgctcc tgttgcccct gttgctccat ctgctcctgt tggacctgtt
    11581 gctcctattg ggcctgttgc tcctgttgct cctgctaatc ctgttgctcc tgttgctcct
    11641 gttggaccta ctaatccgtc tgctcctgtt ggacctgttg cccctgttgg acctgttgct
    11701 ccatctgctc ctgtatttcc tgttgctcct gttgctcctg ttggacctgc tactccatct
    11761 gctcctgttg ctcccgtcgc tcctgttgga cctactaatc catctgcccc tgttggacct
    11821 gtcgctcctg ttgctcctgt tgctcctgtt attcctactc ctgttgcccc tgttggacct
    11881 gttgggccta ctaatccatc tgctcctgtt gctcctgttg ctcctgttgg acctactaat
    11941 ccatctgctc ctgttggacc tgttgctcct gttgcccctg tcgctccggt tgctccatct
    12001 gctccggttg ctcctgttgc cccggttggt cctattagtc ctgctgctcc tgttgcccct
    12061 gttactcctg ttgggcctgt tgctcctgtt gctcccgttg ctccggttgg acctattaac
    12121 cctgttgctc ctgttattcc tattcctgtt gctcctgttg gacctgttgg gcctgtcact
    12181 ccaaatcctg ttgctcctgt tgcccctgtt ggacctgtta ctccatctgc tcctgttgcc
    12241 cctgttgccc ctgttggacc tgttactcct gttgctccgt ctgctcctgt tgctcctgtt
    12301 ggacctgttg gacctgttat tcctattcct gttgctccta ctgctcctgt tgggcctgtc
    12361 gctccaggtg ttcctgttgc tcctgttgga cctattaatc ctgttgctcc tgttactcct
    12421 actcctgttg ctcctgttgg gcctgttgga cctgttactc caaatcctgt tgcccctgtt
    12481 gctcctgttg gacctgttat tccatctgct cctgttgctc ccgttggacc tgttggacct
    12541 gttactccat ctgctcctgt tgctcctgtc gctcctgttg ggcctgttgg acctgttact
    12601 ccaaatccta tagctcctgt cgctcctgtt gggcctgttg cccctgttgc tcctgttgga
    12661 cctcttaatc ctgttgctcc tgtattccct gtatttcctg ttggaccagt cggaccggtt
    12721 ggtcctgttg ggcctgttgc ccctacacct ggacctgttg gacccgttgg acctgttggg
    12781 ccggttctac ctcttggacc cattgggcct gttggaccta cacatgatgg tggacagcaa
    12841 tgatggcaat cacagctatt ataatcatca cgaccattgt tacaatcatc atatttatca
    12901 tagccattgt tgtaatcatt atcatcaaat ggtccaaaat atttatttct actcattatt
    12961 aaaagcacct cctgatatat ttgagctttt aagctctata tataatatgt caaatttagt
    13021 atgattgtga cccatcaact atttttaaat ttactaaaat aattttcatt gtgcaaaaca
    13081 gcactatcat taggtttgat ttcttttgtt ttttcatgat aataaatagc tttatctgat
    13141 tctcctaacc tgtcataaca gacacttaat tgtatagatg gtatatatcc ataacaatca
    13201 tctgacttaa agcctccatc agtatcattc ttatctcttg ttaatgctac cttataccaa
    13261 aaaatggctt ctttatattt ttgtctatca aacatatgct ttcctatgtc acaacaaatt
    13321 tctgctcttg gctcatcaaa ttcgaaactt ctaaacaatg aatataaggc acttttttca
    13381 tcattaatta agtaataaca tgtggctaaa tctctgcaag cactgataca atcctcaatc
    13441 catcctcttg atgagtctaa aaacttagta aaaccttcta ttgcttcttt atacctagca
    13501 ttatagtaca actctctaga ataatagaat tggtgtcttg gctccaatgt ttttccttct
    13561 gaaatcattt tttcaaaaat tctaagattt cttagagggt cctgtctatg aagcttttta
    13621 tgagatattg caatgtcaga ataaaatacc tctccaaaaa gaggtactac ttcatgaata
    13681 gggtcaaccc atttatgatt agaacttctt ttaaacaatc gttctctata atatgagaga
    13741 gttgggttac cattttcatc aaaggataca ttgtattttg ccataacaat atcaatggaa
    13801 gtatccaagc tttctttaat ctttaataat ttttctctat cagcttctaa aattatgtca
    13861 tctgcatcaa gccacatagt atagtcttta gaagctttag aaaatgaaaa atttcttgca
    13921 gcagagaaat catctatcca ttcgaaatcg tacaccatgt ctgtatattt tgagactatt
    13981 tcttttgtgg aatctgtaga accggtatct acaattataa tttcgtctac tatatccttt
    14041 acacattcta agcatctgcc tataacttct tcctcattct taacaatcat gcacaaactt
    14101 attgtaatca taatgtacaa ctcctttgtc ttctatatat tgcagacata agtaatatat
    14161 ggtattttct cttgttttgt tattaaattt ataaaaactt ttgacgacag aaagttacta
    14221 aagaacctta tcttttatgt attttttata gtagaattta ttaaacttga aatttggtaa
    14281 taattgtcga aatgataaaa ccatatttaa tttcatacaa aaaagagtgt cccataaact
    14341 aaaaagttca ttttgagaca ctcttattta atattatata tatatttgta aaacagacat
    14401 tttaatatga tactttgata ctttattcat tcctattcat tatataatca atcagcccgt
    14461 actctttagc ctctagtgca gtcataaaat tatctctatc tgtatctctc ctaatatctt
    14521 ctattgattt acctgtattt tcagaaagaa ttttatctaa tcgttctttt attttcaata
    14581 tattatctac agctattttt acatctgttg cttgaccttt agctcctccc attggctgat
    14641 gaatcataat ctctgaattg ggtaaagcac atctttttcc atgtgttcct cctgcaagta
    14701 aaaaagcact catgcttgca gccataccaa tacaaatagt cgatacatca catctgacat
    14761 aattcatagt atcatatata gcaaatcctg atgtagcaga gccaccaggg ctatttatat
    14821 atataattat atctgaatct gggtcttctg attctaaaaa cagtaattga gctactacta
    14881 aacttgcaat agcatcatta atttcttctc ctataaatat aattctatct tttaataatt
    14941 ttgaatatat atcataagac ctttcccctt gacctgtttg ttcaattaca tgtggcacta
    15001 aactcatgct actttcacct cacaattaat attaaagttc agataagaat tgatttcatc
    15061 tcttctttgt ttataattca tatttgcata agaaatacat ttttcacttt gaatttgatg
    15121 atttagattt aaaacaaatc tctgttgaat aggataaaat tcatctttat ttctatatac
    15181 ttgtggagat tctttatata aatttctaaa tgctagtgta aaagattgat gtgtagaata
    15241 tcctactgta atagctatgt ctataatata tttgtctgta aatataagtt gtctagctgc
    15301 ttcagtaagt ctcctcctct gtatgtattg atggatagta catcctacaa catttgtaaa
    15361 cattctgtgt aaatggtatt ttgaataatt agcaatataa gctattttat ctaaatttag
    15421 attttctgta agattttctt ctatataatc aattatctcc ataataacat ctgtatttgt
    15481 tttcaactct atcctctcct tttaagtatt ataacctatg caaaaagttt tttcttaata
    15541 taaattgcta tcttaattta gtgtatagca ataaagtatc gataaaaaaa tatcaggtat
    15601 ttttatacaa aaatattaat atatatttct tttaaagttt aaacttaatt acatctatta
    15661 tatgtagatt gctacatgtt ttatctatgt accttgattc atatgtatta ttttgctgag
    15721 tatttttaca cctttttcaa tttcatcaaa actaagatga gcataaccta gtataatttc
    15781 atagtcatat tctaatatat tctcaattgc atattgttgt ataggataaa cttttatacc
    15841 tgcttcaaaa attttatgaa ttaaactttc cgtaaattta acattataga aatgagcaac
    15901 tatatgaagc cctgctgctt caccttttat tttaaattca tttttaaatt ccgtgtttaa
    15961 aacttttatg aggtacttac gttttctatt gtacaacttc ttcattctaa atatgtactt
    16021 ctctaaacct ccatttccaa taaattcagc taatacatgt tgcaatattg tttctgtatg
    16081 aacatcagag tacattttta aggttttata gctttctaaa atattgtctg gtaataacat
    16141 aaatccaaca cgaatagctg gagataatat tttactaaaa gaacctatgt aaattacttt
    16201 atttggacta agttcataaa gagaactaat tggttgaccc tcatatctaa attcactatc
    16261 ataatcatct tcaattatat agtaatcatt ctctgttgca catttaataa gctctagtct
    16321 tctttgaata ggtaaaatcc ctcctaatgg gtattgatga gaaggtgtag tataaacaaa
    16381 agaaatcccc tttattgatt ttattaagtt ggtattcatt cccttatcat ctactttaat
    16441 tccaacaact gaatatccaa tagatgaaat aacctttaat aagcctttat gaatagggtc
    16501 ttctacagca acctttttat tacttttgta taaaagctgt gaaattaaag ataaaccttg
    16561 tgttgaacca gaaacaatca taatgttttt gggattacat ctaattcctc tagtacgaaa
    16621 taaatactta gatatttcca ctcttaaaac ccatacacca gctgtacttc catatctgaa
    16681 atccgaatct gataaatcat acagtatttg tttatatagc tttgaaagtt ctttgcgtgg
    16741 aaatagtttt aattctggaa ctcctgaacg aaaatctata taattttttt gtttattagt
    16801 atgtaaatct ttttcatctc taaaagtatc atttaactta aaatcaactt tatgccctga
    16861 tattccttta gctacaattg ttccatatcc attccttgtt tccaaatatc cttctgcaat
    16921 taattgatta tatgcatcta aaactgtatt acgagataca gatagttctt ttgataaagt
    16981 cctagatgat ggcagttttt gctcaaactt taagcttcca tccagaatca tatcttttat
    17041 ctcacaataa atttgtcttg ataatgatat attactattt ctattaatcg taatccacat
    17101 tctaatacct ccaaaagtgg ttctataaaa ttactataaa aatggaacta caaaatccac
    17161 ttttaatttg ctaagattat atcataaaat ataaaataaa aaggagtcta tattatgtta
    17221 gaaatatcac ataaagttaa agaaatttat cccaatatta aatttggagt tatggttata
    17281 aatattacac attcaaaacc taataaagaa aattttttag ttcttaaaaa ctctacaatt
    17341 aaaaatatta tagaacaaca cccagaatac aatcgtaaag aaaaaattaa aacagagcct
    17401 gtttcaagtt atataaagta ttataaaaaa ttcaagaaaa cttaccctgt attgcttcaa
    17461 ttagaatcta ttctattaaa atcaaaaggt atcccagatg taggtgtaac aattgagtca
    17521 atgtttttag cagaattgaa aaatcttctt ctaacagcag gtcatgacct tgataaaatg
    17581 gaattacctt tgaaaataga attagcaaat ggaagtgaac atttttatgg tataggtggt
    17641 aaagaacata ttttaacaaa agatgattta tttttatcag ataatattgg tatattatct
    17701 agtattctta atggccctga taatcgaaca gctataacaa aagatactaa aaatattatg
    17761 tattttgtat atggacctga taaaatatca gaaaagcaaa ttcaagacca tttaaatgac
    17821 ataaaacact atatttcaag tgcttttcca gatttaaaag ttaattcaat tgatatattt
    17881 tagttaatat attaaaatcc tcataaatat tttgaataaa taaattagtg aagtatacat
    17941 tctagttaaa ctagatatac ttcactaaaa ttaattatat gtagatatta tttattttga
    18001 attttgttta taataaacac tttattacat ttatcctatg aataacttaa ttttataatt
    18061 aaagagtttc ataagaaaca atttcactta aaggaacacg agttttttca tgtctctctg
    18121 ggctctctgg tatcttagat tcatatccca tcaataatat atttattggt tctagattat
    18181 ctggcaaact aaactcttct ctaattatat ctggattaaa atagcacacc caaacacttg
    18241 ccaatccaag ttcagttgcc tgtaacatca tatggtctgt aactatactt gtgtcaatat
    18301 ctgtaagttg tttcccatca aaaggtcttg tccaaacttt gtctttatct ccacatacaa
    18361 gaattgctaa tggagcatca tatatattgg cagccttaga aagtttattt ataccttctt
    18421 tttcctgaat aacaatcaat ctttgaggtt gacgattacc accagttgga gctattcttg
    18481 caacatctaa aaccttctca agtttttctt tttcaacctt tctatcttga taattacggc
    18541 aagaatatct tttttttgca agttcaacga aattcattta tttacctcct attgttttat
    18601 taggctaagt tgatgattta tttaacctat gctataattt tatcactatg gtactatatt
    18661 acaataatgc acttttttgt aatatagtac ctaaaaagat actttaaaat aaataaagga
    18721 gcccaaaaat gaaaaaatgt ttagataatt acagttgccc aatagaagca acacttgcat
    18781 tgattggtgg taaatataag acacttatac tttggcatct taaagacact atattgaggt
    18841 tcaatgaatt aaaaaaatta attcctaaag caacgcctaa gatgttaact caacaattac
    18901 gtgaattaga atcagatggt ttaattataa gagtggttta tcctgttgtt cctccaaaag
    18961 tagaatactc gctatctgat tttggaaaga gtattattcc aattttagat tccatgtgtg
    19021 actggggttc tgattactta gaaaatctat aaaccattac agtttaaatc ccattgctaa
    19081 tttaacttca tccatttgtt ctttagatgt caacatttct aaaagcttaa aagctacatg
    19141 tggagctgtt tctggacaat atgaggttat aatattttta tctacaacaa ttggttcatt
    19201 aactacattt acatcaaact cacttaactg tctttgtctt ttaccatttt tcaaatgata
    19261 tgtagtagct ttacgatttt ttaaaacacc actttttcca actggcaatg ctgccacaca
    19321 aatagaagcg attatttttt cttttgaatt aaactccctt attagattta aaaaagatga
    19381 atcatatgct tcatcataaa atccaaattc ttcaaatccc ccaggaatag ctagagcatc
    19441 ataatcatca acacatactt cttctatcgt cttatcaact aatacttgta tattaaatgt
    19501 gctcataact tgttttttaa atccacaagt cactacatca atatcatgcc cataatcgtt
    19561 acgagcccat cccataacat ctacaaatac actaaattcc atagtttcaa aaccttttgc
    19621 taaaaaaact aaaactttca tattctattt tcctcctaaa atataattaa cactttacta
    19681 gtaaattatt taaaaaatat cttttattgt attaaattct tctttaattg tagataaaac
    19741 aatggttgta ttagcttttt gaatcccccc aatttccttc aaagtcactg atataaactc
    19801 ttcaagatta cttgtatctt ctgctaatac ttttattaag taatcatact ctcctgaaat
    19861 atgatgacat tctaatacag tatcatattc caatatagtt ttcttaaatt ctttcatact
    19921 tttagataaa tcagtattga taaatataaa agccaaaagc ttatattttg ttttttcccg
    19981 attaatttga atagtgtact tttgaattaa atttgactgc tcaattttcc ttatacgctc
    20041 tgagactgct ggtactgata aattaatttg tctgcttatt tcagaggttg aagccctact
    20101 attctttttt agagaattaa ttatttttaa atctatttca tccagagcta ctcacctcct
    20161 taattattta atacaatttt agctaataat ttacattaag taaataaatt taatcatttc
    20221 aataaaattt aatacaaata tgttattttt ccttaaaatt ttagttttct ttaatcaaaa
    20281 cacatataat acttaaaatt atttaagttg aattaatgtt tttattttgt ataatatatt
    20341 agaaccttaa tatatcattg aaaattcaac aataatagac atatacttct acatgttgta
    20401 atatttatga aaatagtatc cctatatcaa aattataaaa ctcataatct taattttctt
    20461 atagactata aaattttatt gatagcgagt cttcaaataa ctttgtaatg atagatttac
    20521 taaattaata taataatagt aaatataact ttcttattga ctataactaa gtattatgat
    20581 aacataactt aagctataat taataaaaca tattttaaat aaataagata atccacaaag
    20641 tacaaaagta caatttaaat acagataaac tagaattaat actaagatta ggatgtgaat
    20701 aattatgatt tatatagaat tagttaaact tgttagaaaa cttaactcta cacaaatgta
    20761 tacgatgaag cgttgtgtag aggttaatct gaaagcttaa agctttctat cttcatcggc
    20821 aaatataggt ttagtatagt tttttggcta tgcttattta aaattaccta tttgccgata
    20881 gataatatag attttctggt catagacaac aatgcttgtc tatgaccttt tgtttttcca
    20941 aaagcagagg tcggcatttt acaatgccat tcctctgctt tttttatttc cataaatttt
    21001 ttaataaaag aaaaggagtt tgaattatga gtttattaaa agtaactaat ttatcacaat
    21061 gttttatgga taaatcactg tatgagaaag ctaactttga tttattcaaa ggtgaacata
    21121 taggtgtagt tggccaaaat ggtacaggta aaagtacatt aattaaaatt ttattgggag
    21181 aagttgttcc agattcagga gaaatcaagt ggcaacctaa tatcaatata ggccatttag
    21241 accaatatgc agaaatcaat agagatacaa caatatcact ctatttacac actgcatttg
    21301 aagaacttta taaaatagaa aaggaaatga atttactcta tcaaaaaagt gctatatctg
    21361 aaaatgagca atatctaatc aaagcatcag attatcagga acaactaata gcaagtaatt
    21421 tctattctat agataatgaa ataaataaaa tagcaaatgg tcttggatta gattcaatag
    21481 gaatgaatcg tgttgttgga gagcttagtg gtggtcaaag ggcaaaggta attttagcaa
    21541 aattactact ttctaaccat gatgttctat tattagatga accaacaaac tttttagata
    21601 aagaacatgt tgaatggctc tcaaattatt taaatacatt taatggggca tttattgtag
    21661 tttcccacga ttttgacttt ttagaaaaaa tttctacagg tattcttgat atagaatttg
    21721 gcatgattaa gaaatatcat ggaaaatatt cagagttcct taaacaaaaa tcacatttaa
    21781 gagaagatta tattagaagg tatcaagcac aacaaaagaa aatagaaaaa gaagaaacat
    21841 ttatacgtaa aaataaagct ggagtaaatt caaaaattgc aagaggaaga caaaaacaat
    21901 tggataaaat agaaagaata gctcctccta gttttacagg aaaaccaaat attcaatttt
    21961 cagaaattga aatatcggct caaaatgctc ttactataac aaatcttgaa gttggatact
    22021 actattcttt acttccaaaa ttaaatttct ctgttgatgg aggtcaaaaa atagttataa
    22081 ctggttttaa tggaatcggt aaatctacct tgttaaagac attagtcaaa gatattcctc
    22141 gtatatctgg agatttccag ttttcagaac aagttaaaat tggttattat gagcaagatt
    22201 taaaatggga aaatcctgat aaaaccccac ttcaaatagt agcagataaa tatccaaaat
    22261 taaatacaaa agagattaga cgtcatctag ccagatgtgg tgtgaaggaa gagcatgttt
    22321 caaggagtgt atctacttta agtggtggtg aacaatctaa ggttaaatta tgttgtatga
    22381 tgttatctcc ttgtaatttt cttatcctgg atgaaccaac caatcacttt gatgcagaga
    22441 caaaggatgc tttacaaaat gctttgaaac agtttagagg aagtataatc ctagtttccc
    22501 atgaagaaaa attttataaa ggttggattg ataaagtatt taatatagaa aaacaattag
    22561 tataagttta tacacaatat acaatattat ttaattagta tttcaatgca aattttaatg
    22621 ttctagttaa tgtttcactg caaataaact aaaaaaattt tattagaaga taaagtacat
    22681 taccaggata taaacttaat gaggctatct caaaatagag atagacctct tcttcattgt
    22741 tgagataacg aaaatatatt tgattttacc cataaaagaa tgcctcatta actaaaaatt
    22801 caacttgaga tatcttcatt aatattaaaa tctattctaa tcgattctat tcacaagttt
    22861 atatcctagt cctttaactg ttataagtat tttaggattt gaggggttat cttcaatttt
    22921 ttctcttata tgtcgtatat gcaccataat tgtattgtca caaatactac tatatactcc
    22981 ccatacttgt tcatagagtc tttcttttcc tataatttta tttacatttt gagccatgta
    23041 gcttaaaaga tgatactccc ttccagttaa ctcaatctca tttctatctt tatatacacg
    23101 gtttccttct atatcaatag taatatctcc tattttaata acttcactat ctgatggtac
    23161 aatgctttga tactgttgtc tacgtaattg cgctttaact cgaaaagcaa tttctcttgg
    23221 actgaatggc tttgttatat agtcatctcc cccactacta agacctagta ttttgtcaat
    23281 atcatcattt tttgatgata aaaaaagaat agaacagtat gaaaactctc gaattttttt
    23341 acacacttct ataccatcta tatctggtaa cattatatca agaatgacaa catctggaca
    23401 tgctatctta cacagcgaaa tagcatctag accattataa gctttaataa tgtttttaaa
    23461 accatcattt atgagtactt cttcaattaa atctactata tccttttcat catcaacaag
    23521 taatattttt ttattaaaac atgtatccat attgaaatct ctccataaaa atttattata
    23581 ttctaatctt gcagtatcac tatcttgttt tttatattca ctactcttgc ttttacatta
    23641 ctaatagtaa catctctaat agacaaattc aatcactatg aaaattaaga taagtttctt
    23701 taaaataaag tgtatgatac attaaaacct atagaaaatt aatttcatcc aaagtttata
    23761 atattagact aatacactta cagatacaga ttaatacaat agtaaaataa aaggagttgt
    23821 cttaaaattg actttttcta atcaaacttt aagttcaact cccttttaaa cttttatatg
    23881 ttatttttat taattcttta tatcaattat aactttaatt ttcaatagta tatatctccc
    23941 actaattgaa ttacttatta aaacataaaa tatctaccta aactatttat ttaatatcta
    24001 catatattta tatctattct tatacttaca tatacaaaaa atggttaaaa ataaagttaa
    24061 aatctcagca cttggtactg ctaaccatat cccatttata tttaatatat ttggcaatat
    24121 caataaacct atagttataa atccaaatgt acgtagaaaa gataatattg cagacacctt
    24181 tccatttgat aatgctgtaa acatagacga agtaaaaata ttatacccac aaaaaataaa
    24241 actaaaagaa aatatataaa atccagacct tgcaatttca taaactcggc ttcctctttg
    24301 agaaaaaatc tctacaatga ttggtgaaca tgatatagaa aagataaata ccaataaaga
    24361 tgctactgaa ataaataata tacaaatctt aaaaacatga tttaactgcg tattattttc
    24421 acttccatag ttataactta ttattggtgc aacacccatt gagaaaccta tataaagcga
    24481 agttaaaaga aattgagaat aaataattat tgtaatagct gcaaccccat cttcaccaat
    24541 taatttcatc atcatagcat taaataaaaa agtagtaact gctgttgata gttgacccac
    24601 catttcagat gaaccattaa aacaagcttc aaataatatt cttttatcta gtctaggtat
    24661 acaaaattta agtaaccctt tattttttga aaagaaaacc atacctgaaa cggtaggaat
    24721 taggtatcct actccagttg caagtgctgc tccactaata cccatttgta acagaacaat
    24781 gaacacatag tcaagaatta tattagcaca cccagcacct aacactagcc ataatccaaa
    24841 ttgaggcttt ccagctgtta caaataaaca ttgaaataat acttgtagta tatttgcaga
    24901 agcaaaaacc aagataataa aaagatatga acgacaatat ttaattaaaa cttcacttgc
    24961 tcctaaccat ataatgatat aatccataaa tacaatacct ataccagtaa ttattacccc
    25021 aattacaact cctgataata cgattaaaga aaaagcttta tttgctccct caatatcacc
    25081 atttcccatc ttacgtgcta caatagcact tcctccagtg gcaagcatag ttccaattcc
    25141 aactataaga ttaataattg gacatacaat attaattgct gatagagcat ttgtattaat
    25201 aaatcttgat acaaatatag tatctacgat tgtatacaac cccataaaaa tcatcataaa
    25261 aatagtagga aatgcaaact tcaatagagt aaataaatta aatctttgtg ccagtaaatt
    25321 atcttgctca taaagattat cttgttcatg attttctgaa taatatacat cactcatttt
    25381 gtttattttt ctgtacatta attattttta aaatatattc caaacaatta gacatttaca
    25441 gacctccttt ctgcataaga attatatcta attatttgga tatagtttta attaatcttg
    25501 cttttttaca caattatatt tctactaaag aaacttttaa atccttactt taataatttt
    25561 atagctttca gtgcctttag cgcaaatact tgttcacata gtttagtgtc atatgaaacg
    25621 tatttatata tagttataca ttgtctattt ttactaattt attaactact tgcactttta
    25681 taatgtctca tacctaactt ccaaaatctc cacataaaca atgtaaacaa aaatacaatt
    25741 aaaattgagt atattaatcc attaattgtt attgtcccag ccaaaatttg agtcggaatt
    25801 gtcgacataa ttccatatgg taagattaaa tagaataata ctttaaaaac accttcatat
    25861 attacaccag gaattttcat attcattggc aataaattat cttctaatct cattatcgca
    25921 gaagatgata taacaaaaaa tgaaactgtt ctaagtatga tacatacatc ataaaaaagt
    25981 aatgtcatca ataacaccat gaaaatatat attattatca taactaaagt tatctctgag
    26041 tttaactcag atattccata taaaacaata agtatacttg ctagaattaa tggtgatgaa
    26101 ccaatattaa tattttcaaa tgttaaccta aatagtgggt ctaatggttt tgtaatatag
    26161 tagtctaatt ctccttcttg gatttttcgt ggaatatcat aaataccaaa aaagaaaatc
    26221 gtcatattta tcgcatttat taatgagaaa gttcctataa atattaacat ctctccttgt
    26281 tgccatcccc ctattgagtc tacatgagaa tatatactat taaacattag aagttgtaat
    26341 ataaataatg aactatctac aaaaaatgct ccaaaaaaat cgaatctaaa taccatcatc
    26401 tttgataatt tcatttttaa taacataaat attattttca aatttttttt catcatatac
    26461 ccaccccatc aaataatgtt ctcattcttt tatacataac tttatttact acagaaaaaa
    26521 ataaaaccca taatgctaga ataattaatc cttgtattgc ctcattgctg tttctaccta
    26581 ttagtaacat agatggcaaa tatgttgtat aataaaatgg aaataccttc ataactgtta
    26641 ctatagtttc tggtaagagt acaagtggta tcattgttcc tgtaataaat tcaacaatat
    26701 tttcaattat cattttaaaa aaactaatct caagaaattt aaatgacaaa atcccaataa
    26761 agaagtggag tttcatcata aaaataaacc ctagaaaaat catcaaaatt gaaattaata
    26821 tttgaactgg atttgatgta aaggcaaaat ctattttaaa tataaaaatc catacaaatg
    26881 cagaaatcat attaaataca aaataaaaac atgtcattcc aaaattttta gcaataaaat
    26941 aattttgaac attaattgga ataatcatgt actttgaaaa ggtgcccaat tttacacgat
    27001 tacatatctc ttcactggta ctctttgaca tatcaatacc tgctaaaaat gagcttatta
    27061 tatagtaaga caacatagag ttaaatgtaa aaccagagac tattttattt tcaccaaaaa
    27121 ttgctttcca taaaatataa gcaaataaaa tttttacaat cgtaaacacc atattaacca
    27181 ccacatcaaa tctccagata agttgcactt taaagttaat tttggctact tcataatacc
    27241 ttctaatact ctgtttaaat ttataaaaca ttgaatcatt tgaacttgct tcattatagt
    27301 tgctcataat actcatcact tcctttctta tatattctct ctacaatact acctatatct
    27361 tcttcttcaa tcattacatc tttaacatca tatttatcaa aaatccattt aatcgtttca
    27421 tttcctcttt cttttggcac aattactgat atcttatgat ttgtttgttc aacaacttta
    27481 caatcttttg gaaatacaat gttagtttca ttggaaaaac taactgttat ttttttatat
    27541 ttttgaaaat gattaaatag tttctctgta gaaccatcat atattttacg gctattttct
    27601 acaacaatac ttctactaca gagactctta atatcttcca tgtaatgaga agtaagtata
    27661 atagtagttc cttttgtttc atttacttct tttaggaaat acctaatttg tttttgggct
    27721 atagcatcta agcctatagt tggttcatcc aaaaataata tttttggatt atgtagaagg
    27781 gctactatta gttccatttt cattctttct cctaaagaaa gcgtcctaac ttgaacattt
    27841 aaatagtcag atacctcaaa taattcgata aagtaatcca agtttttttt atattcttca
    27901 ttagatatat catataattc tttaaataaa agaaacgtat ctgctggtgt caattcaaag
    27961 aatagttgac ttttttggcc cataacaaca gcatattgtt ttttaaaatt attttctaat
    28021 ttgttagggt aataacccat tacagatatt tctccagaag acggtgcaat aataccagtt
    28081 aacatcttaa taagagtagt tttaccagct ccattttgac ctattaatcc aacaaattct
    28141 ccttcttcta tctttaaatc aaatgacaat atagctgttt tttctgtata tttcctatta
    28201 aataaagact ttacactccc cataaatcct gcctttttct caaatcttct ataagcttta
    28261 gtcagttcat taagttcaat tatactcatt ttaactacct ccatatttca taatttatat
    28321 aaaaaaagtc cacaggtata tatctgcctt tttctgtgct tatatttaac agcacaaaaa
    28381 cagaaaactc ctgtggacta gaaaaattaa tgctctctat ttcaaaatag ttatcaaaat
    28441 aatactatac aaaattaata aaagtgtagc agattaaagc ctactacacc ataatttaac
    28501 aaagtaatat atattttaaa tactatttgt tgtcatatgt cagttatcta taaaggcaga
    28561 ataagacaca aaaattaaat gtattaaaaa tacacttgaa atttctgatt atacagaata
    28621 tatgtgtctc caactattta attgttggtt accattatat aactccgaca tcaaggcact
    28681 cctctcataa tattattatt gatatcatat cataaaggtt atttatgttc aagcatggat
    28741 taatatacta atacatttag cttatttctt caaggttgaa tttaaatttc atttataata
    28801 ttcgtttata aattaaaaat ataatacgta tattaaaact ggtcatttta ctgtaatatt
    28861 tttattgtaa aagatatact tttacctata caggatgtaa tttctttagt tctatattat
    28921 aataatattg taataagagt tcaacttata atacattaaa atataaactg taaatcttaa
    28981 gggggtaatc tatggaaaat aatacaatac aaaaacaatt aagagattta tcaaaaaaaa
    29041 tttggcatat ttatatttta aatccagaag aagaaaacct taaatttatt atttccttat
    29101 tagatgacaa ccttgcatta attggaacag gaaaacatga attttacgaa acattagaag
    29161 aatttattat aggtcttgaa aaagaccaaa cagaatcaga gcaaatagac tttgagatta
    29221 tagatgagtg gtattcatgt accaaagtca cagacgaagc ttttatagta tatggtactc
    29281 tttgggtaat agaaaaagat tacctagaaa aagatatcta tgtagaaatg gatactcgat
    29341 ttactatggt atacagagtt acagatgata tgattaaact tatccatgtt caccattcta
    29401 ttccaaactt tgaccaaatg aaagatgagt attaccctaa aacaataact gaaaaagcac
    29461 aagaagcact agcaatggca aatgaattta aactaaaatc agaaaaagac cttatgactg
    29521 gactatacaa tagacatttt tttgaagtac acataaaaga aatgcttaaa actgtttcac
    29581 atggatactt ttacatcttt gatttagata attttaaaca ggtaaatgat atctttggtc
    29641 atgttcgagg agatgaaata ctaatacatt tttcaaatat tttgactaaa gtattcgtaa
    29701 atgatgctat tattggaaga cttggtggag atgaatttgc tgtttttgaa tatagtaatc
    29761 aatcaaaaga gaatgttgaa aataaggcaa agaaggtttt agaattatgc ctagagagta
    29821 attcttgttc tataggtata tctaaattag aaaataactc tgatactttc cagtctttat
    29881 acaaacaatc ggattatgct ttgtattatt caaaacgaaa taataaagga aactttagtt
    29941 ggttttagta caaaagatat taaaataggc aaatttatta gagtatcttg tcctatatac
    30001 taataagtaa agtaaacaac aagctatctt tgcatatatt tatataaacc aactattctt
    30061 aataaaacta caatagtcaa catgaccact attatagaat ataataaact aaaaacatga
    30121 ttaatattat attttaataa ttttattttt aaaagtaagt ccaaaatgtt atatgttttg
    30181 attaaaactg atgttgatat aaaaaatttt acttaaaaaa acacttagaa aggctttata
    30241 aagagccttt tttgctttta ttgattaaat tttcatataa aattccttat taaatttcaa
    30301 atcaataaaa aaaggctcta taagaagcct ccccctattt ttattgatta aatcctaata
    30361 tagacaatgc cttagcatca tagtaagtag tcatctctct tgttgcatcc tttaatttac
    30421 ggtaatcaaa gtctaatgat ccaccaaaag ctgatatttc agacccatca aacctatacc
    30481 atttcccatc aatttgtata tagttccaag catgatttaa tgatggattt aatatagata
    30541 gtgaatccat tcccattaac cttgttaata aatgaaagct acttgcaaaa cttccacata
    30601 caccacgttt atcaaccaga ttaccataga ctatgttaca atatttagag tctgcatatt
    30661 ttgcttcggt taccaatttt gcagctctat tagctctttc catctcagat gcatttctcc
    30721 agtcaaagct atttaaaaaa ttcctgatta ctgtaagtgt atcttgagct tgtttgtaag
    30781 aaatccaatt tccatcagct attacttcta tagggtcaag ttttccaaag cctattctct
    30841 gatatgagcc acctgacaat gctgccgcat aaaatcctag cccttccata cccttattta
    30901 tataataata tttaccatct gctcgaagct caactccatt gggatttcct ccatagagta
    30961 aatcccatcc ctctttacct gttgtattaa gaccaagttg tgttaacatt cctttaagag
    31021 gatatttagg gtcataatta gcacctttac ttattgcatt tgtttgcact ctgccatcca
    31081 ttgtgcctat attagtctga ttacgttcat ttgcactctg ttttttcaag ctagatgttt
    31141 catcttcttg atatggctct gccattactg tcatactcat catcaatata ataatcatgg
    31201 taatcatagt agttaatata ttcttcttca tactactccc ccttatttaa ttctttttaa
    31261 aacataaaac tattaactca taaatatatg gttattagta aattgaaatt aagtctggtt
    31321 cataaattat tggtttaata gaagtgtatt gaaattgtac ctttatattt tcattatata
    31381 ataaacttat ttttttaaaa catattgttt aaatcagtac atttatatgt tttttttgtt
    31441 catctgtttt atcaaatata ttagtctttg aattttgttt gtattcttca gcatttttat
    31501 ctaacttttc tattctcgac tcaagtttca ttatttcttc ttgtgttaaa tttataaaat
    31561 ttttaagcat attttcaagc tcttcacgag ttttacctac taaagataag tcctcagata
    31621 ctttctcttt tttattagaa tcctctttat aatccttttt ttgttctaac tcttctaatt
    31681 tttcatcatt taatatttct tcttcaattt tttcattaga ctctttagtg attaaagatt
    31741 ctttttcatc atttgtattt agataagttg aattttcatc taacattgta cttttatttt
    31801 tctcttctat aatgctattt ttaataccta tttctatatt agaaaaatta ttagttgttt
    31861 ctcttatttc tgatttacat aagttcttaa ttgcgtcatt tattttttta gtataaacct
    31921 cttgtctata ttttaaatct ctaattctat cattaagttc ttgcttttgt ttcataatat
    31981 tagataaata agtgtctttt cctacagttt catttttctt aaccatactt tcatttattc
    32041 ttgtattatt tatattactt tcatatctaa atgaatattg acttctatat tgactagata
    32101 ttttcattta tttcacctcc ttaaaataaa tttatgttta taaaaaccaa cttaacttaa
    32161 ttatatttta tcatcaaaag tatacattta caaatattag ttaatagttt tataggttcg
    32221 agcattattt tcaacaaaaa atttttatta taaattaaaa caataatttt tataaatata
    32281 ttatttgtat tttataattc atatattttt actttataaa ttagcaatat tgcagttttg
    32341 ctcttaagaa acatctctat catacataag catatactct attatgtatt agtataaata
    32401 tgccttttct tatcttacat aagacctctt tataaaggag cctatcgtaa caaatatgta
    32461 tacattatca catgtatata tcatcatata aaaaatcaaa ctttattaaa aaaattaata
    32521 aattgcttta aataatacca caaaccaaat ttgccatcaa aatcacatta aagtaacaaa
    32581 ttgatggcaa atttaatata ttaatagtat atagactcat agaatgaaca aaaaaactac
    32641 acttatcttc taatcttctt atttattttt gagatatttt taaatttctt ttcttttttt
    32701 gctaagtatt cgcttttatt gtctgcaaat actgcttcag ttttaagcct acgataggat
    32761 tcccatcttt taggcgaaag ttcttgatga gcaatagctt cccagatagc acagcctggt
    32821 tctgaggtgt gagtacaatt acgaaaatga cattttccga aataagcttc tatatctgca
    32881 aaacttttat ctaaaccttc tgaaacatcc cacattccca actctctcat acctggtgtg
    32941 tcaataacaa taccaccacc tgaaattaaa aatagctctc gtctagtcgt ggcatgtctt
    33001 cctttatcat catctatgcg aatttccttt gtatttaaaa attctccacc catcagacaa
    33061 ttaattaatg aagattttcc aactcctgaa gaaccaagta aggcaacagt acagcctggt
    33121 ttaatatact tagaaatctg tttataacca tctggctcta tagatgaggt aacaactaca
    33181 tctacaccca aggctataga attaactact tgtaatttac gatgcacatt gtcacataag
    33241 tctgatttag taagtactac tactgggata gctccacttt cccatgttaa agacagatac
    33301 ctctccaatc tatgaatgtt aaaatcctta ttcagtgaca tgcacaaaaa aacaatgtca
    33361 atattagctg caaccacctg ctcctcattt acctttccag cagccttacg cacaaacaag
    33421 ctttttctat gaagcacatg atgaataata gcattaccat ttttattatt gcaacgatcc
    33481 aacataacga aatcaccaac tgtgggaaaa tcagattgta tagtagcctc aaaacgcagc
    33541 tttcctgaaa cctctgcaaa cagtacacca tttacacata cagcttgata aaagttcttt
    33601 tcctgcgaga taatccgagc aaggtataaa tcatgatatt ccatactttg agtaataaaa
    33661 tttctattta gaccatagtc ttgtaaattg atttgtttca taccattcat tctgtttcct
    33721 ccttttccaa cttttcaatg attctttcta gtgggaaagg gggctgtgcc agtggtttta
    33781 atgcaattga cattaatttc actgaattat catcagctgc aatacgatta gaactaagat
    33841 gtccacagcg tgtacaacga tgaataattg cccactcacc attttttctc acccacactc
    33901 caataggttc catattagca tcacaatctg cagcacggtc accaggaatg atatctacat
    33961 gaagactatg taaacaatgt ggacaatgat ttctatgttg tgtaccagct ccttcaggaa
    34021 ctacaaggca accacaattt ttgcaaataa agttatccat acaggaattt tcctgataat
    34081 aagctcgttt tctattttta taattcattt ttatttcctc cgtatcgtgt attttctaca
    34141 aaaaaagtcc acaggtattt atatctgcct ttttatgtgg tatacatatt tacctacaca
    34201 aaaacagaaa acccctgtgg actagaaaat ttagtatctt ctatttcaac ataattatat
    34261 tcaaaataat actgtgtaaa attaataaaa gtgtagcaga ttaaagccca ctacaccaca
    34321 atttaacaaa gtaatatgta atattattat ttgttgtcta atgttagtta tctataaagg
    34381 cagagtaaga cacaacaatc aaatgtatca aaaatacact taaaaattct gattaaacag
    34441 aacccatatg cgtctccaac tatttatttg ttggttacca ttatatataa ctctgacatc
    34501 aggcaagaca ctccttcact aataattatt attgaaattt tatcataaaa tataagtatg
    34561 ttcaagtata atttaatata ttcatatatt tatgtttgtc tcattttctt attctataaa
    34621 atctagtggt attttgaaat ttaatgttca cctagtatta ataataaaaa ttaactgcta
    34681 ttatttgttt tctcatttta tgcctgttgc tcaatttatc tcacttaaat taataacaac
    34741 tgtcttttca tacaaaacct acaatcaagt ttttccatat attctacatg catagtctat
    34801 tttttttgat ataaaataac gttcatattt gtaaatttat ttaattttca aataagtata
    34861 ttgaataata agcaattcta ttgtattatt gtaattgtag aataaaacta aatcggcaaa
    34921 actagagaaa tttagtgacg caaagctata gggactaacg cttataaaat aaactatgag
    34981 ttatgtcagc cagttgccaa aaagagatat tctttttgtt tttatgaaag ttttttaggg
    35041 ggataataat atatatgttt agagataaaa tggatagatg tacacatatg ttgactgctt
    35101 atattggtag ttcatatgat tattgtgatt ttatagatac acaactagat gattttatac
    35161 tagagtacgg agaaaatgtg gtagaatctt gtttgcatca agtgatggta ttagtaagta
    35221 agtataatta aatagatttg gttttctaga gaaccctttt tagttttatc tactttaaat
    35281 agccttatgt tagaaagcta attaagatag atttctagta ttcataattt tattttttat
    35341 ttaaaataca tataataaag atgtaaattt gtatcaaata ataaatatga gaacttaaat
    35401 tctcttatct atgtgaaaat aaacatctct taaaatgaaa ttctgtaaat ataaatgatt
    35461 ttttagtttg aaggattaga ttaacaaaat tataaatttg caaataagct atattaaaaa
    35521 atataataat tttttatata acttattctt ttataacttt taattttaaa agaggagaat
    35581 gtatataaga gtattcaatg tactagaaaa aatcaaaaga aatattagaa gaaatggata
    35641 ttgagtaatc aaagaaaaga ttttgatatt acaaatgata tgtttcaaga aagcattcct
    35701 atcacaacaa aaattattct tgaagacatg ccttcaaatg atgaattaaa tcatgttttt
    35761 tcaaaaggtt gtgaacgaaa aatgaaaaag agaaaaattg tattaatcac actactatta
    35821 ataggtgttt tgttattagg aagtatccta tataatcttt ttttaggaaa aacagctaat
    35881 atttcaatgc taaaggaatc ttggaatttt gatataccaa tacctaacaa agaaattgaa
    35941 gtatttgata ctcaagatag tattaatgga gatggacaaa gttattttat tcaaggattt
    36001 tctgaaaaaa atttcaaaaa agtttttaat ttaaaaggtg gtatagttgt aagcaaagat
    36061 aatattaatg aaatagaaaa atatattgat aaatttaaaa gagattctgt taacattaat
    36121 aaaagtaata aaaataaaat tgaagaagat tttaaaaaat ataagttaga agttaaaaaa
    36181 gatgataagt atatatataa gagaaattat gagaactacg tagttttaat tataaaaaaa
    36241 gatgaacaaa aattatacag tttaatatgg aatcagtagg tacatatgta ttattaagaa
    36301 ttataaataa taaaaataaa ttttagtcaa tatacaaaaa ccttttaaat tgtctggaaa
    36361 tcacctcttc atttgttata aaaacataca acaaatgaag aggtgatttt atggttttaa
    36421 aaaaaataat tataagtgga tatgtgcttt cacatgttta tcaacatttg taatgcctat
    36481 atttgctaat gaattataaa aatattaaat aatattcaac tatagattat gtaaattact
    36541 ctatgaaaaa aatgagttgt ataaaatctg gctactgtag attgactatt tcttttaaaa
    36601 ttacaattat aataagtttt atagaattaa aaataaaact ttagagattt ttgataacat
    36661 tgtagactaa atttgccacc gaaatcgctt tacagtggca aatcggtggc aaatacaata
    36721 tattattagt atataatcta tataaacatt actattgttt gattatctta gctacagttt
    36781 ccacatgtgt agaatgaggg aacatatcta caggttgtgc ctcaacacat ttaaatccgt
    36841 gaacatttag ataatctaaa tcccttgcta aagtagaagg attacaagaa acatagacaa
    36901 ttctttccgg attcattgaa acaatagtct ctaatacctt ttcgtcacat ccctttctag
    36961 gtgggtctac aacgactaca ttggcagtct taccctctct atacatctta ggtacaattt
    37021 cctctgcctt tccaacataa aattcagcat tatgtatatt gtttaattta gcatttatct
    37081 tagcatcttt tatggcatca tctataattt ctattccata aaccttttta gccttttgtg
    37141 ccaaaaataa agatattgta cctatcccac agtaaatatc aaaaacagta tcagtatcat
    37201 ttaaatttgc atattcaaga gccttatcat acaatacttt agtttggaca gggtttactt
    37261 ggaaaaatga taatggtgaa atctcaaaca ctaagtctcc tatataatcg tttatttttc
    37321 catctccata tataactata ttttctcttc ctagaatagc attcgtatct ttttgattta
    37381 catttacaac caaagtctta aatccaggta tattttcctt aagcactgaa gctaattctt
    37441 taagatatgg aagtttgttt ccatttgcta ctaatacaac cattacttct ttagttgtaa
    37501 aacctatttt tgttactaaa tgcctaatca accccgtgtg agtcttttca tcatatatgc
    37561 ttaccttata ggcccttata tatgttttta ttattttaac aattttatca tttatctcat
    37621 gttgtattac gcatttttct gtcgatatta catcatgagt cttcttttta tagaagccaa
    37681 taattggaat accattattc ttttgtattg gaaattgtgc tttatttcta tatctatatg
    37741 gattatccat tcctatagtg tcatgaactt ctacatcctc taacttacct attctcgaaa
    37801 gtacttgttt aacttcattt gttttcattt caagttgttt attataatct aagtcttgta
    37861 tctgacaccc tccacaatcc ctaagattgt cactacacac tcttttcacc ctgaatggag
    37921 acttttctat tatctcaaca atatctccca cagcataatt tttctttact ttattaatcc
    37981 taactttaac tttatcatgt attaatccgc cctctacaaa aactgtaata ccattgtact
    38041 ttcctactcc tactccgcct tgaccaatgt ctactatatc tacaatatac atctcgtttt
    38101 tcgaaagcat aaatcaccct ccaatcaatc tattatattt aaatctttac aaactttttt
    38161 ctttaaattt atattaaaat attgctatta attaaactat attttttact aagctacaat
    38221 attttatttt accaaaaaaa aaggagctta taaagcccct tagtaaataa atttattatt
    38281 tttcttataa aactctagtt gaacctctat ataccacgcc tcttgatgca tccacagtta
    38341 caacttctcc atcttttact agatttgtta tatcagctgc agacacaata actggtatat
    38401 ctaaatttat acctacaata gctgtatgtg atgtcattcc accattctca gttactacag
    38461 ctcctgcttt ttctatataa ttgttcattt cagcatcagt agcagtagaa acaagtatgt
    38521 cgccttcatt aaagtctaca caagcatttc cattctttat tatacgaact ttaccttcta
    38581 ctgtttgagt acctacacct ataccttgca cgatttcttc gcttattaca tgaaccttta
    38641 ttaaattagt agttccactt actcctactg gtactccagc agttataact actaattccc
    38701 cattatctat ataatcagct tgtctagctg cctcaattgc cttttctata acttcatctg
    38761 tatttcctgc aacagaagac ttaactggat atactcccca tgtaagagct aatttattca
    38821 tagtcttttc attatttgta gtagctatta ttggagattt tggtctgaat ttagatacca
    38881 ttctagcagt atatcctgaa gaagtagatg ttattatagc tgatgcattt aaatctactg
    38941 ctgttgtaca agttgcatgg cttattgcat ctgttacagt aacattgtta gtaccatttt
    39001 cctttagtaa tctatcataa tctaaagtct cttctgttct ttttgctatt gtagccatca
    39061 tttttactgc ctctacagga tattttccag cagcagtttc tccagataac attatcgcat
    39121 ctgttccatc atatatagca ttggcaacgt ctgtaacttc tgctcttgtt ggtcttggat
    39181 ttcttatcat agaatcaagc atttgagtgg cagtaacaac tggctttgct aattcattac
    39241 atttttttat catcattttt tgaactattg gcatctcttc agttggtatc tcaacaccta
    39301 agtcacctct agccaccatt ataccatcag aaacttttaa tatttcatct aggttctcta
    39361 caccttcttg gttttctatt ttagatatta tttgtatatc agttgcatta ttgttctcta
    39421 atacttctct tattgctagt acatcagatg cctttcttac aaaagaagca gctatataat
    39481 ctattccttg acttattcca aactctatat cacttatatc tttaggagtt attgctggta
    39541 aatttatctt aacaccaggt acatttactc ctttatgatt tttaactatt cctgaatttt
    39601 caacaacaca aactatatct tctccattta tttcttttac tcttaagcca actaaaccat
    39661 catctattag tatagaatct cctgatttaa cgtcttcagc aagaccttta tagcttactg
    39721 tacacatttc tttagtcccc ataatatctt tcatagttat agtgaacttt tgcccttctt
    39781 ctaaaaatac ctctgggtct tcaaagttac ctgttctaat ttctggacct ttagtatcta
    39841 ataatatagc aactggctta tttaattttt ctctaacttt ctttgccata tcaattcttt
    39901 ctttatgttc ttcatgcgaa ccgtgagaaa agttaaatct acacacattt agaccatttt
    39961 gcataagttg agttaaaact tcctcacttt gtgatgctgg acctagtgta caaacaattt
    40021 ttgtcttctt tacattattt aacatatttg ctcctcctga gatattattc cacagattta
    40081 tttttaatac taaaacttat atagataata tttttgccat ctcataagct tctttatcaa
    40141 atactttctt ttgagctaaa gcttcactta tttctaaatc aattattttg ttttctttta
    40201 ttcctacaac tctagctgat tttccatcta ataataattc tactgctctt actccaagtc
    40261 tacttgctag tattctatca gatacagttg ggcttcctcc tctttggaca tgccccaata
    40321 cagtgactct taaatctgct cctgactctt ttttaagttc cttttctaaa tcactagcac
    40381 ttccgactcc ttctgctaaa acgattatac tatgtctctt acctcttttt tgagtagtct
    40441 ttaatcttag agcaacttca tctactgtaa tttctacttc tggtactatt atagtttccg
    40501 ctcctcctgc aagacctgca tataaggcta aatctccaca gtgtcttccc ataacttcta
    40561 ctatgttaac tctttcatga gatgatgatg tatctcttat cttacctata gcatctataa
    40621 tagtattcat tgcagtatca aatcctatag tataatctgt atatgctaaa tcgttatcta
    40681 tagttcctgg tatgcctata gctgggaatc ctaagtcact aagtttttgg gctcctgcaa
    40741 atgaaccatc tccaccaatt acaactaagc aatcaatttt atacttttta agaattttta
    40801 ctgcttttaa tctaccttct tctgttttaa attcttcaca tctggaagat tttaatatag
    40861 ttcctcccct gtgtataata tctccaacag aagataagtt catttcagtt aaatcttctt
    40921 ctagtaatcc cttatatcct ctattgattc catatacttt gcatccataa tatattgctg
    40981 atcttacaac cgctctaatc gcagcattca ttcctggagc atctcctcca cttgttagta
    41041 atcctatagt tttcattttt tacctccttg gattttatgt caatttttta ttataatcat
    41101 tgttattgta ttctaatgga ctttttttgt ccctatatca ctttttaatc ccatcaagac
    41161 taaaaaaatt aaatgtcctt aaatgtccat tttgtgatat tatatcacaa aacggacaat
    41221 atttttcata ttattataat atatttagat ttttatataa aaaatcaagc ttttactttt
    41281 atgttatctt taggaagtaa ctcttctaag ttatttataa attcatcaca tatacaagtc
    41341 aatgccccgg tcattttata tgctttacgt ttaccattta tattttcatc catagggtat
    41401 aagtatatac tgtcattacc tggatattgt ttggctattt ctacaatatt attagttgta
    41461 tcagtatcag acatactatc tattttcaaa tacaattttt taccactttc tggcttaata
    41521 ttttctacat ttctagttct tcctgaattg tagtttctat ctgcaaagtc agtatcatca
    41581 tttatatctt ttatctctct agctataagt tttgcatttt cgccttcttt tatacttaat
    41641 gttcctttta catatattat attatcttca ttcaaaatga cattatactt ttgtaataat
    41701 tgaggaaaaa ctattatttc tatagcacca tacaaatctt ctaattcaat aaatgccata
    41761 atttcatttc gttttgttgt tttaatagtt ttagttacaa tcattccacc cattataaca
    41821 tctgtttcat tcatttgtag gtatgactct tcttcctctt ttaatgaatt taattttcca
    41881 ttatccatag atgttttttc ttgtagttct ttttcaaatt gtgataaagg atgtccactt
    41941 acatacattc ccaagacttc tttttcaagg ttaagtctct ctctttcttc gtactcttgc
    42001 cttttaggca aactgtatat ttgttgaaaa tcactatctt cctcactatc tccaaaagca
    42061 tcaaataaag aaatttgacc ttgaacattt ttctttctat ccatagatac actttctaat
    42121 aaactttcat aaccagccat cagactagct ctattttcac ttatattatc aaaagctcca
    42181 cattttatta gactttctat tactctctta tttgtatctt tttggtctaa tcttttgact
    42241 aaatctacta aatctacaaa taatccatta gattctcttt cagcgattat attgtttatt
    42301 atatttacgc caacattttt tacggctgct agaccaaatc ttatattgtc gccttcaact
    42361 gaaaactttg aaaaactttt gtttatatct ggaggtaata catctatttc tagtgcttta
    42421 cattctctta tatactcaac taccttatca gtatttccca ttacactggt tatcaatgct
    42481 gccataaatt caactggata atatgttttt agataagctg tctcatatgc taaaacccca
    42541 tatgcagctg catgtgattt attaaatgca tatctagcga agtctatcat atcatcaaat
    42601 attttattag ctatttcctc ttctacacca tttctgatac accctgcaat ttctatatta
    42661 ccatcttcat caaatttacc atgaataaaa tattgtcttt cttcttccat cacgtccatc
    42721 tttttcttac tcatggctct tctaactagg tcacttcgtc cgtaactata accacctaaa
    42781 tctctaacga cctgcataac ctgctcttga tataccaaac aaccatatgt aacttccatt
    42841 ataggcttta atttttcatg tagatatgtt acatcttttg ggttgctttt attttttata
    42901 tatgcaggta tagaatccat tggacctggt ctaaataggg atattcccgc tacaatatct
    42961 tcaaaattgt ctggttttag ctgtttcata aaacttctca tgccagcact ctccaattga
    43021 aacaccccta gtgtatttcc tgatgaaagc atttcatata ctttcgggtc gtcataatcc
    43081 atctttgaaa agtctatttt ttctgtgtaa ttttttataa ctctattttt ttctattaaa
    43141 tcaagagtat ctcttataac tgtaagagtt cttagcccaa gaaaatccat ctttaaaagc
    43201 ccaagttctt caagtgttgt catagtaaac tgtgttgtga ttgcatcttg atgtttgtac
    43261 aaaggtacat attcatctac gggatttttt gatataacaa ctcctgctgc atgagtagaa
    43321 gcatgtctta gcattccctc tatctgtttt gatatattta ttatttcttt tgtttccggg
    43381 tcttggtcat acaattcttt aagattagga tttgtatcta gggccttatc tattgtcatt
    43441 cctaaagcaa atggtatttc cttggctacc ttgtcaactt tattgtagcc tatatccaat
    43501 acccttccaa catctcttat tgcagctttt gcacccattg ttccaaaagt tattatctgg
    43561 gctacatggt catcaccata ttttctcttt acataatcta taacttcttc tcttctctca
    43621 taacaaaaat ctatatctat atctggcatg gatatacgtt ctggatttaa aaaacgctca
    43681 aataatagag agtactttat tgggtctata tcagttattt taagtgtata tgctactatc
    43741 gaaccagccg cactacctct acctggtcct actataatat tattttcttt agaaaaattt
    43801 ataaaatccc aaacaattaa aaaatactct acataaccca ttttttcaat tacatctaat
    43861 tcataattta atctctctag tatctcatta ctaggattat catatctctc ttttaatcca
    43921 ttaaaacaca actcccttaa ataagtttct ggtgtatatc cttctggaac atcatactta
    43981 ggaagatgta tagtattaaa atcaaactcc acattacaca tatcagctat tttcacagta
    44041 ttgtcaatag cctctaatgc atatggaaat aattcttcca tttcttctct tgattttaaa
    44101 taaaactcat cactaccaaa tctcattcta tttgggtcat ttaatgtttt tcccatttga
    44161 atacacataa gtacatcatg tattttcgaa tcttctttat ttacatagtg aacatcatta
    44221 gtagcaacta gtggtatacc agtctctttt gataatttta ctaaaccaga gtttacttct
    44281 ttttgctcag gtaaattgtg atcttgaatc tccaaaaaga aattttcttc tccaaatatg
    44341 tctctgtagt caagagcaaa ttgttttgct ttttcataat ttctattcat taaagcacgt
    44401 gctacatctc ctgcaaggca tgcagaaagt gctataatcc ctttgttatg ttttttaagt
    44461 tcttccatgt caactctagg cttatagtaa aaaccttcta cgtatgaagt tgaaactatt
    44521 tttattaaat ttttatatcc ttccatattc ttagctaaca gaactaaatg tccttgatat
    44581 ttgtcatagt ttgggtcttt atctctcaat ccacgtgcag ctgtatagac ttcacaccct
    44641 ataattggct ttattccttc ttttatagct gttttgtaga aatctataac accaaacata
    44701 caaccatggt cagttatagc tattgagctc atgtttagtt ccttagccct ttttataagt
    44761 tttttcaccc tcgaaaaccc atcaagtaaa ctatactcag tatgtacatg aagatgagca
    44821 aaatctttgt tcattaaatc acctcctgct ttataatttt aattttacca caaatatatg
    44881 tcctaaaaca aaaacagaga cttttatctc aaaataggaa ttaacttcaa cgtataccat
    44941 tatatgttat aaattaatgc ttattctgag attgtcccct caatttattg ctatgatttt
    45001 tttttcaaat ctgttgcaat ttcttctatt tttctaagtc tatgattgac tccagatttt
    45061 cctattggtg gttctaacat ctctccaagt tctttgagag tcatatcctc atactcgatt
    45121 ctaatcttag ctatctcttg taaattttct ggcaaactgc taattcctat agtctcttgt
    45181 atgagcttaa tattttctac ttgtcttact gctgcattta ctgttttaga aaggttagct
    45241 gtctcacaat ttactatcct gtttacatta tttctcattt cttttactat tttagtattt
    45301 tgaagactta aaagagcgtg gtgtcctcct ataatactca acaaatctga tatttgttca
    45361 ctctctttga tataaacaac gtgattattt tttctagcca caattttact attaaaacct
    45421 aaagagttta taagttcttt tagagaatct gcaaactcct cattattagt tacaaattcc
    45481 atatgatagt tcttttctgg gtcgcttata gaacctccac caagaaaagc tcctcttatg
    45541 aaagctctct tacatccttc atgcttaatt aagttctctg aaattttgtt tatagtaaaa
    45601 aatccttctt tatcttcaag tatacctaac ttttttaata acatttctga acccatttcg
    45661 cttgttacca ttaatacata actgttattt ctctttagca tttgattctt atttactgag
    45721 attgtagtat tgatattaaa attctttttt aataatttaa atactttacg ggctattgaa
    45781 tttaactctg ttgttatctt tagatttagc ttcttatatc caacaatttg tatacttccc
    45841 cctgatttaa ctagagctga caattcagct atattacaac attcattccc agatataact
    45901 cttgctagtt catttttggt ttcagttgaa aaagacatat ctatcaccta ttaactaatt
    45961 tttctttaac ctttttttta tttcttgtaa ggcaaccttt attatctcct tttcatcatc
    46021 atacctagct aagtctacta ctctatctag gtggataaat ttagcatcaa taaagccttc
    46081 ctctttttgt ggaatagtat ccatattctt tgcttgcatc aaataccaaa aaactgtttt
    46141 atgaactgct ctattttcat cccagttttc tttgaatgta tagtgtattt cacctaaata
    46201 tttcaatata tctgctttta ctccagtttc ttcacttact tcacgtaatg ctgcctcttg
    46261 gttattttcc ccttcttcta cttttccctt gggtaacacc caatctccat tgaacttcct
    46321 tagtaaaaga atcgtattgc caaacaggac tacaccacca gcactaacct cttctctcat
    46381 cgatgttcac tccttaaaac taacataatg ataaggattt ctacacaatt ttttaaaatc
    46441 cttttttact aacttttgtt gtaattatga tttagggcta actcaataac tatgttagat
    46501 atatactttg catcatgtct tatataatta ttttttattt caattaaatt cttctctaca
    46561 gtttttatac ccatctcttt taatttatct ttttgctttt tatctaacaa gacttgctct
    46621 gctccatctt gtttatataa gtcaagcatt tcttctggca atatctcatt atttgcgatt
    46681 acataatcta ttaaattctc atcagtgtgt tttactatag cattaacatg ctctaataca
    46741 ttgtaccctt ctgtctcacc tggttgagtc attatatttg ctatatatac ttttggagct
    46801 acagacgatt taatagcgtc tacaatcccc tctacaagta aatttggtat tatacttgta
    46861 tataaacttc caggacccat aattataatg tcagcatcat aaatagatgc aataacatcc
    46921 tttaatggtt ttacatcttt tggatttaaa aaaattttat caatagagct tttttgaatt
    46981 tttgactctt caggtatact agattctcca tttattatat tgccattttc taatttggca
    47041 actaaattta catcttccaa agttactggt aaaactcttc ctgttatagc aaaaatttca
    47101 cttaatttat atacagcttt ttcaaagttt ccatacaacc cattcatagc agccaaaaac
    47161 aaatttccaa aactctgacc ttttaaaagc ccttctgtaa acctatattg cataacttca
    47221 ttcattgttg gctctatatt tgcaagtgct aataaacagt ttcttatgtc tcctggtggg
    47281 agcattccta agtcttctct caatacacct gaacctccac catcatcagc aacagttaca
    47341 attgcagtta tattttgcgt agtgtgttta agacctctta aaaataccga ttgaccagta
    47401 cctccaccta tcacaaccac atttggttct ctattttcaa caatagacct ttgaaatagt
    47461 tttacttttt cattttttgc ttttttatat ataaataacg atacaattaa tgcaatccaa
    47521 cctaaaattc ctacaataat aagtaattta gccatgtttg cctccattat cgcaacatag
    47581 agtctctatg tttctttaca actctatatc ccttattaga taaatcctcc gctataagat
    47641 ttgttatagt aactgaccta tgtcttccac ctgtgcatcc aacaccaatt actagatgtt
    47701 gttttccttc ctctatatat tgaggtacta aaaaatgaat catatctaaa agtttcacat
    47761 aaaattcttc actgatttta gaattcataa cataatctct aacttcttta tcatcaccag
    47821 ttttagctct taactcttca acataatagg gatttggaag aaatcttaca tcaaatacta
    47881 aatctgcatc agcaagtata ccatgtttaa atccaaaaga tactacagaa atagttaggt
    47941 ttggattatc ttcaccagaa gaatatattt tctttatttc ttccttaagg tctttaggtt
    48001 tcatgttagt tgtatcaatt atacatgtag ataactcctt taaaggttcc attatctttc
    48061 tttccatttt tataccttct ggaatctgca tatcttttgc caatggatga tttcttcttg
    48121 tcattttata tctctttagc aatacatcat cattacaatc caaatatacc atttcatatt
    48181 cataattttc tttttctaaa taatttaagc tttcatgaag cgcttcaaaa aactttctcc
    48241 ctcttatatc tatccctaga gcaactttat caatacttga atttggttga taacataatt
    48301 ctgcaaattt agttatcaaa gcaggaggta gattatctac acaataaaat cccatatcct
    48361 ctaaagctct cattgtctca ctttttccag atcctgaaag acctgtaact ataacaaatt
    48421 tcattgctaa ctcctccctt ttatcttatg tttattatat tataatgttt tctactaacg
    48481 atatatccag attagagtca gatatagtct tcatagctag ttcaaaatca ccaactcttt
    48541 ctggacaatg tgcatctgag cctattataa atttattttc tagccctttt attttattta
    48601 attgatttac attcaaaaaa gaatggctac tatttatctc aagtctagta tttgtctttt
    48661 ttgctgtctt tgctacttct tctatataca catcgccttt atctcctgga tgagtaatta
    48721 taaaaatatc attattactt atcgcattta ttacagcttt tgtattatat tcttttgctt
    48781 tttcagtttt aaaaatatag ttattacaat gatttaataa gcttcttaat gatgttggag
    48841 tagaaccaaa atgatatcca gccataatat aatcaaaatc tctaataaat ttatcatcca
    48901 tatctatatt tcctttatca tctaatatgt tacactccat acctaaaagt atatttatat
    48961 cagtgtactt atcatttaaa taatctactt cttctctcat tttgagaata tcttttttct
    49021 ttacaccata tgcaatatgt ttataactat ggtcagatat tcctattgtt tttattcctt
    49081 tagaaatggc tacctttaca ttatcctcaa tagtcccttt gccatgacta tataatgtat
    49141 gtgtatgata atcagccagt attttcattt gttaatcctc tccaagtatt ttgacttctt
    49201 cttccaacat aaccccaaac ttggcatata cagcactttt tataacatat attaaatcca
    49261 aaatatcttt agcacttgct tctccttgat tgactacaaa tccacaatgc ttctcagata
    49321 cttgtgctcc tcttaaagta agacctctca atccagtttc ttctattaat ttacctgcaa
    49381 aatatcctgt tggtctctta aatgtacttc ctgcactagc aaaatttaat ggctgtttag
    49441 ttattcttct cgtcgctaaa tcatccatta aactttttat ttcatcataa tttccttctt
    49501 gtaattctaa ttctgctgat aaagctatat atccgttttt cgatattata ctttttctat
    49561 acccaaattc catctgttca tttgataatt caaatatatt gccttccata tccatcagtc
    49621 ttactgactt cactatatcc ttcatttcac caccatatgc tccagcattc atggctaatg
    49681 ctcctcccaa tgtgccaggt attcctgatg caaactcaaa cccttttaat tcttgctttt
    49741 ggagagcttt ccctaaaact gataataaag ctcctgactg agcagtcatc ctagtatcat
    49801 ttatctcata agaattgaaa ttatcagcta attctattac cactcctctt attccaccat
    49861 ctttaattaa aatgtttgaa ccatttccaa ttattaaata cggaatagac tcttttttta
    49921 ccaacttaag tacatttttt aattgttctt cagttctagg tctaactaat atatctgctg
    49981 gtcctcctac cctaaatgaa atatgttttt tcataggttc atcgactttt atatcctctt
    50041 tacttaatat atttaataaa tttatatata tatcttgatt attcattgta tttcctccca
    50101 aattatactg aactttagct gtcattatta tttaaattac attaatatat agtattaact
    50161 atattcaata atatatgatt ttgcttatca tatggatttt atattttaag cttcttaatt
    50221 acaaactata ttcaataaat atataataaa gtaaaaaaaa aaaaataaca acatataaaa
    50281 gaatataaat aatttaaaaa aagcatcaat atcactgata tcaatgcttt aaaaggcaat
    50341 ttaattcgta ttatttatct aactattttt gacatagcaa agataataaa tccctccaac
    50401 tactatggaa cctccaacga tatttccaag tgttacaaat accaaattag ttataaattg
    50461 aaccatagtt atatttgctc ctaatgccat tcccattggt ataaaaaaca tgtttgcaac
    50521 actatgttgg aatccacata atacaaatag cattattact gtccaacatg aagccaattt
    50581 tgacattata tcttgagatg ctgtagccat ccatacagct aaaacgacta gaatattaca
    50641 aagtattgct tttaaaaaca ttgatgctat agttgaatta accttagctt ctgccacagc
    50701 tatagctttt gtagctgcat ctcctgtcaa tgtagaagaa taaaacacaa gtgcaactag
    50761 caaaattgaa cctactaaat ttgcaaaata aaccagtccc cagtttctta acatttttcc
    50821 taatgttatt tttttgtcca taagtgcaat agccattaaa gtgtttccag tgaataattc
    50881 tgctcctgcc actactacaa gcataagacc tactggaaag accatagcac ttaaaaagct
    50941 agctacccct gggtctatct tgccaaaagt ttgactaact atcatactcc ccaatgcccc
    51001 aaaacctata aatgctcctc caaataaacc taatagaatt gcattttgtg tcgaaatatt
    51061 tgctttttta atgcctgcac ttatagttgc ttgtgcagtt tccccaggtg tcaagaatcc
    51121 tttactcata aatccttccc ccttaaaaat tatactttcc cttgtctttt tatggcaata
    51181 attatataat aacaatatga tatataataa attttattaa cataaaaaat atactatata
    51241 cttatatata cttgtctcat ataattatac tatttattat ataacaactt tgttaatttc
    51301 gaaataattt atattgaatt tgaaaaattt accttttgat tatttatttt actttttaat
    51361 tattgaggta ttatatataa tagatatatg tttgtgttat tatatataat tacttatttt
    51421 aataaatatt tgaaggaggg aattttatgt ttgatatatc atttttcgaa atgtcaatat
    51481 atgaaatagc agttactaca atatatataa ttaatttcat ggttatacta aaccttatct
    51541 ttagagaaaa aagaaacata aatacaactt taacatggct tcttatatta gtattgattc
    51601 ctgctcttgg attcatactt tatatagctt ttggcagaaa tatttcaaaa aacaatatgt
    51661 ttagattgaa agaaaaggat gataagataa tcaaaagtaa tatactagat actcaggtta
    51721 aactccaatc tacatctgaa attgattcag atatacatca acataaggat atgatttatg
    51781 cattggctaa ttcaaataat gctcattata ccaataataa cgatgtgtgg atttatgctg
    51841 aatctagtca attttttaac agtcttcttg aagaacttaa aaaagctaaa aaatatataa
    51901 acatacaatt ttacattttc aaagatgaca aaatcggaac tgaaataata gacattctta
    51961 tagacaaagc taaagaaggt gttgaagtaa gacttttatt tgatgcagtt ggtggtagaa
    52021 cactaaaaaa tagtacactt tccagactta aagaaagtgg tgttaaagtt ggaagcttct
    52081 tcccatcatt cttgaaaatt gtaaacttta acttaaacta tagaaatcac cgaaaaattg
    52141 ttgtcattga tggtaaggta ggatttgtag gtggatataa tgttggtgat gaatatttag
    52201 gtagaaatcc aaaatttggt ctatggagag atacacatac taagcttact ggtgattgcg
    52261 taattgacct aaatatgaga ttcatccttg attggagata tacaactaaa gaagacttag
    52321 atttagaaaa atactttata gaagaagata caaattctaa tcatccttct gaaaatattg
    52381 ggattcagat agtatcaagt ggtccagata tatcagaact tgatgagatt aaatatggtt
    52441 accttaaaat gattcagaaa gctagaaagt atatatacat acagagtcct tatttaatac
    52501 ttgactcaac ttttatagat actttaaaaa tagcctgttt atctggtgtt gatgtgagag
    52561 tgatgattcc ttctaaacct gaccatccct ttgtatactg ggcatcatat tcatatgctg
    52621 gagaactttt aaagtttgga gctaaaatct atacttatgg tcaaaatgca tttttacatg
    52681 ctaagacaat agttatagat gactctatat gctctatagg aacagctaat atggatatca
    52741 gaagttttga gcttaatttc gaagttaatg catttatgta ctcttcaaaa aaagcattgg
    52801 aacaaagaat tatatttgaa aatgatattt taaattctaa ggaaataaca ttagatatat
    52861 ataattctag gtctacttat ataaaaatca aggaatcaat ttcaagacta ttatcagcag
    52921 ttttataaat cttttatttt ataaaaattt tacattttgg tttatttttt aaagtttttt
    52981 atatgtatta tttttttttt attgaattta gctcattttt tttatttttt ttaactattc
    53041 tgaattattt tatattataa tagactagta tagtttttat ttttaatagg taactttttt
    53101 gcattgtttt tataaataaa gaaattgttg tatattattc tttctttatt gttttggttt
    53161 tgttcaccca cataatgttg gggtcaactc atggttaatt attttatgaa aaataataac
    53221 tttaaaaaga aaagggggat ttgttatgtg cgattttatt tcacacaaca agcaattatt
    53281 tgacgaacta gatatattta ttgactctct tgcaacaaag gaaggtgcgt taatacaagt
    53341 tctacatgaa gcccaaggta tatttggata tcttccaaaa gaagttcaac ttcatgttgc
    53401 tagaaaactt ggagtagctc ctgcaaaggt atatggggtt gttacattct attcttattt
    53461 tactacagaa cctgtaggta agtataaaat cagtgtctgt ctaggaactg tatgttttgt
    53521 aaaaggtgct gacaaaatct taagtgcttt tgaaaaacag cttggcataa aagttggaga
    53581 aactactagt gattttaaat tttctttaga aggtttaaga tgtttggggg catgtggttt
    53641 agctccagtt gttactgtaa atggtaaagt ttatggtaaa gtgaaacctg accaagtaag
    53701 cgaaatatta gatacttata gagaattaga attgaattgt taagaggggt gaataaataa
    53761 tgcgtaaagt aaattcattt gatgaattaa aagttttagc tgatgagctg aaacctaatc
    53821 ttagcttaag aaaaaattat tctaaggaaa atgtattaag aagagaatta cttgtttgtt
    53881 gtgatactgg atgtacatct tcaaacagtc tagaaatagt tagtgaatta gaaaatgaaa
    53941 taaagaaatc aggaatccaa gataaagtta gtgttcgttt gacaggttgt tttggtttct
    54001 gtgctcaagg tcctattgta aaagtttatc ctgataacgt tttctacgta aaagttgagc
    54061 catctgatgc tgaaaagata gttcaaagcc acttaattag aaatacagtt gtcgaggaat
    54121 tattatatga ggaagaatct ttaagtaaaa aagttgaaga acaagaagaa atgtctttct
    54181 acaaaaaaca gttacgtata gctttaaaaa attgtggtct tatagaccca gatagtatag
    54241 aagaatatat tgccaatgat ggttatttag ctctaggcaa atgtttaact tctcttactc
    54301 ctcaagaagt tattgcagag gtaaaaactt ctggccttcg tggtagaggt ggtgcaggtt
    54361 tccctactgg ctctaaatgg gaagctgctt caaaaaatcc agctggtcca acagataaaa
    54421 agtttgttgt atgtaatgct gatgaaggtg acccaggtgc atttatggat agatctgtac
    54481 ttgaaggtga ccctcatagt gtactagaag ctatggcaat atgtggatac gctataggtt
    54541 ctgatacagg atacatatac ataagagcag aatatccaaa atctatagaa agattaaaag
    54601 tagccatagc tcaagctgaa aaatacggtt tacttggcga aaatatctta ggcactggat
    54661 ttaactttaa attagaatta aaatatggtg caggtgcttt cgtttgtggt gaaggtacag
    54721 cgctaatgca ttcaattgaa ggtagacgtg gtgaacctag aatgaaaact tatagttctt
    54781 ctaagagtgg tctatggaaa tctcctactt gcttaaataa cgttgagact tttgctaaca
    54841 tacctgcaat tatacttaag ggtggagatt ggtttgccaa cttaggtact gaagattcta
    54901 gtggtactaa agtctttgct cttggtggaa aggtagaaaa tgtaggactt gttgaagttc
    54961 caatgggtac tactttaaga gatattgtat ttgaaattgg tgggggaatc cctgaaggta
    55021 agaaatttaa ggctgttcaa acaggtggac catctggtgg atgtatacca actgaacatt
    55081 tagacactcc tatagacttt ggttcattaa gttctatcgg ttcaatgatg ggctctggtg
    55141 gtatgcttgt tcttgatgaa tctgactgta tggtagatat agccaagttc ttccttgagt
    55201 ttactgttga agaatcttgt ggtaaatgta caccttgtcg tataggtact acaagattat
    55261 tagaaatatt aactaaaatt acagaaggta atggtactct acaagattta gatgacctag
    55321 aaaaccttgc tgaaactata caaactgctt cattatgtgg tcttggtaaa gctgctccaa
    55381 accctgtttt aagtactctt caatatttca aagatgagta tatagctcat gttgtagata
    55441 agaaatgtcc tgctggtaaa tgtcagaact tactttctta ctttataaca gatgactgta
    55501 agggttgtac aaaatgttct agagtgtgtc ctgctggttg tataacaggt tctgttaagg
    55561 aacaacatac aatagatact tctaagtgtc taaaatgtgg tgcttgtata gataattgta
    55621 catttaacgc tataatcaag aaataactta tttggaggag gaataacaat gagtttagtt
    55681 aatttaacta ttaatggcaa acacgtttca gcacctagtg gaacttctat cttagatgct
    55741 gcgaaattaa taaatataaa aatacacaac ctttgtcatt tacatatgaa tgaaatagat
    55801 aagcttgaca cttgtgcttc ttgtcgtgtt tgtatggttg agacagagag aggattagtt
    55861 ccagcttgtg gaacagttat aaaggaaggt atgaaagttc agactaatag tgctaaagca
    55921 ttaaatgctc gtagaactat tgttgaatta ttgttatcag accatccaca agattgtttt
    55981 gtctgtgaaa aaaatggaga ttgtgaatta cagactatag ctgctgattt aggagtaaga
    56041 aaaataagat atcaaggttc taaatctttt gcaggtaaag atacttctac taaatcttta
    56101 gttaaagacc attctaagtg tatattatgt agaagatgtg agactgtatg taatgacata
    56161 caaacagtag gagcattatc tggagttaat cgtggattta atactttagt tagtacattc
    56221 tttaactctg atatggttga aacagagtgt acattctgtg gtcaatgtat atctgtctgt
    56281 ccaactggag cattaacaga agtagataat gtacctaaac tttgggatgt tttaaataaa
    56341 aaagaaaaga ctatagtagt gcaagttgct cctgctgtaa gagttgctat tggtgaagag
    56401 tttggattag aaccagggtc aatctctaca gggaaaatgg tagctgcttt aaaagcactt
    56461 ggatttgaac atgtatttga tacaaacttt ggtgcagatt ttactataat ggaagaagct
    56521 actgaattta tagaaagaat ccaaaaaggt gaaaatcttc ctatattaac aagttgttgt
    56581 cctgcatggg taaacttctt agagcacaat tatccagaca agttaaactt agcatctagc
    56641 tgtaagtctc ctcaaggtat gtttggttct atagctaaaa actactatgc acctaaaata
    56701 ttaggaatca atcctgaaga actttatgtt gtatctgtaa tgccttgtgt agctaaaaaa
    56761 tatgaagctt caagagaaga attaagtgaa tctggaatac tagatgttga cctttctata
    56821 actactagag agttagctaa gatgataaaa gaagctgcaa tcgatttacc taatcttcaa
    56881 gaccaagatt ttgataatcc tctaggaaaa tctacaggtg ctgcatctat atttggagca
    56941 agtggtggag ttttagaagc tgccctacgt acttcatatg agaagataac taataagact
    57001 ttagataatg taaacttcac taatgttaga ggtcttaaag gaattaggga agcaagtata
    57061 gatgttgatg gaactacagt taatgtatgt attgtaaata cacttaaaaa cgctagaaag
    57121 attatggata aggtcagaag tggagaatgt aaataccata tcatagaagt tatggcatgt
    57181 cctggtggat gtgttggagg tgctggtcaa ccttatcacc atggtaatac tgaaatagtt
    57241 gatagacgtg caaatgcgtt atatgaaata gatagaaata aggctattcg taaatctcat
    57301 gagaatcctg atttacaagc tatttataaa gacttctttg gagaaccaaa tagtgatgta
    57361 gctcataaat accttcatac tcattacttt gataagagtt gtgtctatgg agagtgtcca
    57421 caagaatgtg cttgtgaaga agctaagtag tcataacaaa gtataaaatt tattcttaaa
    57481 aaaggattgt cttaaaatac ttttacgtaa tttaagacaa tccttattaa tttcacaaat
    57541 taaattatat ttctaaatag acttatttat taattaacct atctattaat taaagaatac
    57601 ctgccattct cataagttgt tttgcatttg tagttttaca tcttccatct tttatcttat
    57661 agtcaaaatg aattttatcg tctacatagt actctgagaa atgatagttt acaacttcaa
    57721 catctccgct acctgaaagg tcacatagct caaagtcatg tgttgtcacc atacttataa
    57781 cccagggttt tgataatttc tttactgcct cacttgctcc aataattcta tcagcagagt
    57841 tagttccctt aaaaatttca tctactagaa ccaacattgg cagttctttt aaactatatt
    57901 gaatcattga ttttattcta agaatctcag catagaaagt tgatattcct tgacttacat
    57961 catcttgtat tctcatagaa gtaaatatag ccatacaggt cgcatcaaaa ctcttagcgc
    58021 atactggagc acctgcatat gccagcacta agtttacacc gatacttctt aaaaatgttg
    58081 tctttccaga catatttgaa cctgtgataa tacaagtctg agaatttaat tgtatcgaat
    58141 ttgctatgac acttttttct gctattaatg ggtggtatac ctcttcaact ttcaatcttg
    58201 gagtatcttc atattttatt actggaaaac atgtattttc ctttacatga gaaacaactg
    58261 ttaaacttat tagagcttca aattctccaa tagattcaaa ccaatctcta atttgatttc
    58321 catatatacc tttccatcgc tccaaagctt ctgcacaatg atagttccac atcaaaacac
    58381 cacaggcaat tatatatagt atctgattat accttaggtt tacagcattt cctattgaat
    58441 ttaattgttt aacacctctt gaaactccac ttcccttaga aagtttatct tgtaattctt
    58501 tcaaatatgc actctcaaac gtctcttttt ctaaaacctc aaacattttt tcatatactt
    58561 gtatacttct actaaatgaa aataatggag caagagtttg cataagtctt ggatatccaa
    58621 aaccactaaa ccctaactgg attataaaaa gtaaaaaaac aggtaaaaca ggtaaaaatc
    58681 ctaacataca aaatataaaa gataagattg ttgcagttgg taaaccccaa gtaaaaatat
    58741 gcatccattt tggtatatac acattcttat tttctccata ttctataaac gattctatac
    58801 tactatctga attgtttttt tgctctttac caattatatt actgagtgtt tgaatatgaa
    58861 tagaaaaatc atcttttgat aaaagttctt ttatagctct ctgtctttct aaaattatat
    58921 tctcatctgg attttcattc cacaaatatt tggctaaaaa atttttccca taagatgtat
    58981 tagctacaca gatatattga tacaatgatg ctcttccaaa taagtctaaa tcttttgctt
    59041 gcgaattttc atcttttaag tattctttac catctatttt aaattccttc caaccatctc
    59101 caaatctctt aatatactta tttaatactt cgctcttact tttaaaatat gtttcttctt
    59161 cttttacttt actatgaata actaagagtg ctataaatat tattattgat aaaactccaa
    59221 caaaaatacc tactatattt ttattataaa atccaatagc aagccctgct atcactatca
    59281 aaaaagatat taatcttgct gtacttatgt tatttgactt tttacttaag agcaattctt
    59341 tttcagtact actttctaaa agtttactaa aatattctat tcccataaaa aattccaact
    59401 ttcttgttat ataatgaaac tcaaatataa aattaatcta gtattattat aatctaacac
    59461 tgtactttaa attatcctta tataatatat cttattaata aacattatat atacaacttg
    59521 attttaattt ataaggtgta ggacataatc ctaatcaata tttaattaaa tgatgtgtag
    59581 tccactatta ttcagtacta cttagtatcg attaattttg ataatttttt agtaaattct
    59641 tgagctgcat cgtatcccat tcctctttgt ctaaaattca ttgctgctac ttctaatatc
    59701 atagcagtat ttcttccagg tttaacaggt acaactaatt tctctacatt aacaccaagt
    59761 atttcttcat attctttatc cagtcctagt ctatcataat acttagtttc atcccaagct
    59821 tctaaatgaa ctactaaatc tatcatttta gaatttttga ttgcccctac tccatataaa
    59881 cttctaacat ctattattcc tattcctctt atctcaagaa aatgtcttat tagttcaggt
    59941 gactgaccca caagcatact ttcatctaat tttcttattt ctacagcatc atctgcaact
    60001 aatctattac ccctttgaat cagttctaat gctgtttccg actttcctat actactttca
    60061 ccttttatca gtacacctat accataaata tctactagca caccgtgaat tgttgtatgt
    60121 ggtgctaact tattatccaa atagtttgac agtctattta taagtctagt ggtatttcta
    60181 tttgtgctca aaagtattct tttatatttt ttagcctttt caattacatc tggcttgatt
    60241 tccaagtctc tagaaattat taacgctggt atttcatatg agaaaaatct atctagtact
    60301 tcttcccgaa tatgactatc cattaatcca aaaaaattat attctgtctt tccaactatt
    60361 tgtattcttt catatgcaaa ataatcaaaa tatcctgcaa actgtaatcc tggtctattt
    60421 atatcttgag agtagacata ataatctaca tcatcaggca tgtatactac ttttaacttc
    60481 aactctttta ttatctctct tattgatact ttattgctag tttccattaa ttttcttcct
    60541 ttctaaaaaa attataaaca ttatctgcaa tgcttttatt cattccatct acttctaaaa
    60601 gttcttccat agtagctttt tttatagcat ctacatcttt aaagtgattt aataatgatt
    60661 tctttctttt ttcacctatt ccttgtatat catctaagat agattttgtc aaagctttat
    60721 ttcttagact tctatgatat gttattgcat aattatgaac ttcttcttgt atactagcaa
    60781 taaatctata taaattagtt gttttatcta gttctatttc tttttctttg catatcaatc
    60841 ctttagttct atgcttatca tctttgtaca ttccccaaag aggtatatct acatcattga
    60901 gttctagtac tttttttact gcactaactt gtccttttcc accatccaac aatatcaagt
    60961 caggtaaatt tccatgtttt aatcttctat ctacaatttc agccatagaa tcataatcat
    61021 taggtccaat aactgtcttt attttatatc tcctatattc cttcttatct tttttagcat
    61081 tcgtatacac taccatagaa ccaatcgaat ctacaccttg tatatttgat atatcataag
    61141 cctctattct tattggcaac ttttctagat ttaatatttg ctttaattct tccaatgctc
    61201 caatactttt ttcatatttt cttttattca tatcagaaaa tttttcaaga tattctacag
    61261 catttttcct aaccatttca actaagcttt tcttctctcc cttttgagga actcttattg
    61321 ttactttttg ccccttttta gatgacagcc attcttctaa tatagaacta tcttctatct
    61381 catcttctat aattaattct ttaggtatat actcttgttc attataaaat tgttttacaa
    61441 atgaacttaa tatagaagct cttggactat ccattacccc ttctaatata aaatgttccc
    61501 tacctacaat cttaccattt cttataaaaa atacctggac acaagcttca ttatgagctc
    61561 ttgccattgc aaccacatct tggtttaagt cacttacagt agcatctatt ttttgtttct
    61621 gtatcatctc ttcaaggctc tttatcttat ccctatatac agcagcctct tcaaatctaa
    61681 agttcataga actctcattc attttttcct ttaaaagttc catcaatttt tcttctttac
    61741 cagataaaca cattataatc tcttctatca tttttccata ctcttcttta gaaacatttc
    61801 ctgtacaagg tcctaaacat ttatttatgt gtagatttaa acaaggtctt gtcttattct
    61861 ttattgcttt atctatatct attttacagc ttcttattgg atacgtacta cttataagct
    61921 ccaaggtatc attcacagca gttatattgg tatagggccc aaaatacttt gccttatctt
    61981 taagaactct tctaactttt aagattcttg gataatcttc attcgtagtt acttttatat
    62041 atggataagt tttatcatct ctaagcacta cattatactt tggtctgtat ctttttatta
    62101 aattacattc aagtattaat gcctctaact ctgaatccgt tataatatac tcaaacttat
    62161 atatattctt aaccatagat tttactttag atgtatggtt ttttgaagat tgaaaatact
    62221 gccttaccct attttttaga gatatggctt ttcccacata tattatatgg tcgtatttgt
    62281 ctttcattaa atatactccg ggctcagaag gtaatttttt taaatgctct tgtatatcaa
    62341 acatctcgcc ctccaaaaca ttaaatttta tactaaaatt ataccctaaa atatgaattt
    62401 taaaaagtta tacaatttcc agtgctttaa acaagttaaa gcccatattc ccttctataa
    62461 ttgatttgaa aacaatgtta accatgaaga gtaatatgga ctttactttg tattactatt
    62521 tacaacttat atttgactaa tttacttata acaaaacagt ttatcgtata tctgctctaa
    62581 aatttttcac aatttatata acttaagaaa aatatttctt taagaattga cctgtataag
    62641 aaccatcaac tttagatact tcttttggtg ttccagttgc aactatagtt ccacccttat
    62701 ctccgccttc tggtcctaag tctattacat aatcacaagt ctttataaca tctaaattat
    62761 gttctatgac tataattgta tttcctgtat ctgctagtct ttgtaatact tggattagct
    62821 tgtctacatc tgccatatga agtccagtag taggttcatc taatatatac aaagtctttc
    62881 ctgttggtct tttactaagt tcagcagcta attttatacg ttgtgcttct cctcctgata
    62941 attgagttga aggctgtcct aatttaatat atgaaagtcc tacatccatt aaagtttcta
    63001 attttctttt tatatttggt atattttcga aaaactcaac agcttcttcc acattcatat
    63061 ctaatatatc agatatagtt ttatctttgt attttacttg caatgtttct ctattgtatc
    63121 tttcaccttt acaaatttca caaggaacat atacatctgg taagaaatgc atttctattt
    63181 ttattattcc atcaccctta caagcttcac atctaccacc ttttacatta aaactaaatc
    63241 tacctttttt ataacctctt gctttagctt cattagtaga tgcaaaaata tctcttataa
    63301 aatcaaatac acctgtataa gtagcaggat ttgaacgagg tgttcttcca ataggacttt
    63361 ggtctatatt tataacttta tctatacttt caattccttt tatctcctta tgcttaccag
    63421 ctctttgctt aagtctattc actttacttg caacaccttt gtaaagtata tcgtttatta
    63481 atgtactttt tccagaacct gaaacacctg ttatgcatgt aaacttacct aatgggaact
    63541 ttacatcaat atttttcaga ttattttctg atgctttaac tatttctata aaacttccat
    63601 ttccttctct agtagtctca ggaagcaata tttgtttttt accacttaaa tattgacccg
    63661 ttattgagtt ctcattttca attatttcat ctaaagtacc ctgtgcaact atttcaccac
    63721 catgtatacc tgcacctgga ccaatgtcta taacataatc agcttctctc attgtgtctt
    63781 catcatgctc tacaacgatt aaggtatttc ctaaatctgt tagatgtcta agagtagtta
    63841 taagcctatc attatctctt tggtgaagcc ctatacttgg ctcatcaagt acatataaaa
    63901 ctccaaccaa tgcagaacct atttgagtag ctaatcttat acgttgcgct tctcctcctg
    63961 ataaagttcc agcttttctt gataaattta aataatcaag acctacatct cttaagaaca
    64021 tagctcttcc ttttatctct tttataatct catgagctat aaatctctgt ttttctgtaa
    64081 gatttatatt ttccataaag tcaatcaatt catttacaga taagtttgta acttccatta
    64141 tattttttcc atcaactaaa acagataaaa cttccttttt aagtctcatc cctttacact
    64201 ttggacatgg tctctctgcc atgtattctt caatcttatc tctcatgtaa tctgaattag
    64261 tttctctata tcttctctct aagtttacta ttacaccttc aaagtatgat ttataatttc
    64321 tagttcctcc aaattttgac tcataagtaa actctacaat tatattatct ttaccataaa
    64381 gtaattcctc cacaaaatca tctggtaaat ctttaaacgg tgttgtcaaa gatacattaa
    64441 aatgctctgc taaacttttt atcattttac tgtaataagt gtcatcatta acacctgttg
    64501 aaccccatgc tgccactgca ccttgtttta ttgataaatc tttgtttggt actactaatt
    64561 ctgggtcaac ttctttactt tccccaagac cattacaaac atcacaagca ccaaagggag
    64621 cattaaatga aaacattctt ggagataatt cttctatgcc aattccatgt tctgggcatg
    64681 caaatttagt tgaaaaaaga atttcttctc catctattat ttgggctatt acaagaccat
    64741 cagatagctt aactgcagtt tcaattgaat ctgctagtct tgattctatt ccatctttaa
    64801 ttactattct gtccactaca acttctatat tatgtttttg atttttattt aagattatat
    64861 catcactaac ttcatagttt tcaccattaa ctctaactct tacaaatcct tcttttttga
    64921 tattatcaaa gactttttta tgtgtacctt tttgtcctct aacaattggt gaaagaattt
    64981 gtaatttcgt tctatctgga aaatctagca ttttatcaac tatttcttga atagtcatct
    65041 gacttatttt ttcaccacat gtagggcaat acacatctcc tactcttgca aataatagtc
    65101 tcaaataatc atatatttct gttactgttc caaccgtaga acgtgggttt tttgaggtag
    65161 tcttctggtc aattgagata gctggtgata aaccctctat atattctaca tttggctttt
    65221 ccatctgacc taaaaattgt cttgcataag cagatagact ttctacatat cttctctgtc
    65281 cttctgcata tattgtatca aatgccaaag aagacttccc agaccctgac aaacctgtaa
    65341 aaacaataaa tttatctctt ggtaattcta aatctatatt ttttaaatta tgttcttttg
    65401 ctcctcttat tataatttta tcttccataa tgttgttttt acctttctat ttttccaatt
    65461 tttcttctaa ttgtttcact ttatctctaa gttctgctgc tctttcaaat tgtaagtttt
    65521 gagcagcttc catcatctct gattttaatt tatctatatt agctcttatt tcgtctttat
    65581 catctgtatc agatattcca tatacaactt cttcctctgc aaccttagta gcttctatac
    65641 tatctcttat atttttctgt atagttttag gaatgatatt gtgctcttca ttatataaat
    65701 tttgtatatc tcttcttctc tttgtttcat caatagcatt ttgcattgag tcagttatcc
    65761 tgtctgcata cataattact cttccatttt catttctagc tgcacgtcca atagtctgta
    65821 ttaaagctgt ttcggaacgt aagaaacctt ctttgtctgc atctaaaatt gctataagtg
    65881 aaacttctgg tatatccaat ccttctctaa gtaagtttat tcctacaagg acatcaaact
    65941 tccctaatct taaatctctt attatttctg ttctttctaa tgtaactata tctgagtgta
    66001 aatatttaac ttttatccct atttctttaa gatagttagt caagtcctca ctcatttttt
    66061 tagttaaagt ggttataagc actctttcat ttttttctat agttttagtt atttctccta
    66121 ccaaatcatc tatttgatta tttataggtc ttacttctac aattgggtct aaaaggccag
    66181 ttggtcttat tatctgttct gctattgtct ctgagtgttg aatttcataa ggccctggtg
    66241 tagcacttac aaacaacatt tgatttatat ttccttcaaa ttcttgaaaa tttaatggtc
    66301 tattgtcaag tgcagaaggt aatctaaaac cattctctat aagtgatgtt tttctagacc
    66361 tgtctcctgc atacatacct cttacttgtg gtatagtgac atgtgcctca tctacaatta
    66421 tcaaataatc atctgggaag aaatccatta aagtatatgg tctttctcct tctgaccttc
    66481 ctgtaatatg tctagaatag ttctctatcc cctgacaaaa tcctatttcc tttaacattt
    66541 ctatatcata cttagttctt tgttcaattc tttgtgcttc taatagccta tcattttcct
    66601 tgaaaaattt aatttgttct tgaagctcgt tttctatttc tacaattgcc ttttcaattc
    66661 tttctggcgt tgttacatag tgagatgctg ggaatataac aacatgattt ctagtaccaa
    66721 caatcttccc tgttacataa tcaatttctg ttattctatc tacctcatca ccaaaaaatt
    66781 ctattcttat tgctttttca tcattactag ctgggaatat ttctagtata tctcctctaa
    66841 ctctaaaggt acctcgtgta aagtttatgt catttctttc gtattgtatc tctattaacc
    66901 tttttattac atcatctctg tctctttgca tacctggtct tatagataac ataagttctt
    66961 tatagtcttt tgggtcacca agtccatata tacaagatac agatgatatt attatagtat
    67021 ctcttctctc taaaatagat gctgtagcag aatgtcgaag tttatctatt tcatcattta
    67081 tgcttgcatc tttttctata taagtgtcac tgtgagctac atatgcttct ggttgataat
    67141 aatcatagta acttacaaag tattcaactg cattgtctgg gaaaaattct ttaaactcac
    67201 tgtaaagttg tgctgctaga gttttattat gagccattat tagggtaggt ttcttaactt
    67261 gttgaatgat atttgccatt gtgaatgttt ttcctgaacc cgttacacct aataatgtcg
    67321 aaaatttctc atttctattt atagaatcca ctattgattt aatagcttct ggttggtcac
    67381 ctgtaggttt gaagtctgat tttattttaa aatccatagt atcactcctt ttttcgaaca
    67441 ttagttcctg acatgtatta ttatatcata cctttataaa attgtttaag ttattttaaa
    67501 tattttaccc atttaaattt tacttaaatc taaaacataa aaaaagactt ctatctttgc
    67561 aatagaagtc tataattcat ggaaaataaa tactttattc aacttacata ataaaatcaa
    67621 atgcttcttt ttcaactcca tctaatttta aattaaacat ttttaatata gttgctgcat
    67681 gtgctctcag gtctccttct tctataacca caccaccttt aatatttggt ccaaaagcta
    67741 taaatggagg tctattacct ttagtaggta aatgaccatg tgtcgcaaca gcaaacttgt
    67801 aatcttttat atctgaatct tttataatac ttccttcgaa atcatttcca aatgaaattc
    67861 cttcaagacc ttcaattacc atttcaaaat caccttcaag accaaggtta gatgcttcct
    67921 ctttggtaaa aatattctct atgaataatt cttctttaaa ttcttcaagc agttctctta
    67981 actctgttaa cctatctaag ttatttacta ttatttgagc tgatattcca gaagaattta
    68041 cataggcatc aaaatcctta acttctccat tttcaacttt tataaatcca tttgatttaa
    68101 gcaagacatt tggatttata actttatcaa ctctaagatg accatggtcc ccaagtatta
    68161 taaaatttgt atctttgtat gtacctgcat cctttgtagc ctgaataata tctcctagcc
    68221 atttatcatt catttttaat gctttatcta cttcgtcatt aaataagcca taattgtgtc
    68281 gtgtatggtc caatgtagct aaatgtatta gcattaaatc tggtttatat tcctttatta
    68341 tatctactga acagtttact ccaaataaat ccatgttggg ttctaatttc caatcgatat
    68401 aatgacaatg tctattgtaa ataccgtcca ttataacctt actggaactt cgttcaaaag
    68461 tttctcttgg gtcatcttct ctactaggag cccatatttc tgcaatatta taatctatat
    68521 ttggatttgc tcccattaca ggccataata cactagaggt agttagatta ttttcttttg
    68581 ctacatctat aatagttttt gcttttatgt cctttgagta ccagtaccag tctttatttt
    68641 ctttatttgg gtcaaatttt tcattatgat atataccatg ttttttagga tatactcctg
    68701 taaccatact agtatgacac ggatatgtca gagtgggata aacacaattt atatttttta
    68761 ctatggagca attttctagt atagatttaa agtttggtag attttttaca aattccaagt
    68821 ctttttcaaa taaagaatct actgataata ctataacctt tgtcatttac attacctctt
    68881 catttatata ttattgaata cttttaatca acttacaagt ctatataatt atttatttgt
    68941 tttatctatt actgcttgca ttgcagaagt tcctttgctt actacatctt ttggatttgc
    69001 atttaaatca gtaagcccct ttttaatctc atccattagc ttatcagttg cttccttgta
    69061 tccatttaac attggaagtg caacagcata ttgtaattgg tcagttgcaa ccttatattg
    69121 aggtttttct ttatataatg tttgtaactt ttctgagttt gttgcatctt cagttgttgg
    69181 taagtatcct gttgatgaac taaactgaac gattttatct gtttgtgtca tccattctat
    69241 aaattctgca cttgcttctt tttctttatc tgttccacct tcaagcataa ctagattagc
    69301 tccacctgta ggagttgcgt atttttgatt ttttggtaag aatgctgttg atatttcaaa
    69361 cttaccttct gtttgttgca taagtcctgc taaatctgct gttgatgtaa atatcatacc
    69421 tactttacca tttacaaaat cttgttttgc tacgtcccag gcattataat cttctccagg
    69481 aggcattttc attattccag ctttcatcat atcttgccag aacttaactg gtgcttgtcc
    69541 tgcctcatta ttaaatgcta cttttttacc attagttatt tctcctccac tttgcattac
    69601 catagcttca tagaaccaaa tatctattgg tgtttcaaaa ccataagtat cttctgattt
    69661 atttgtcatt ttactagcat aatccttaag ctcttcccat gattttggac ctgaagggtc
    69721 aagacctgct ttagttgcca tatctttatt tatgtataat attggtgtac ttctattaaa
    69781 tggcatacca acaaacttat cctcataata tgaatttgtt aaaagaccag aaaagaatct
    69841 ttcttgatat gttttatcaa aatatttact catatctact aaagcacctg ctgatgcgaa
    69901 tgtacctgtt tgagttattt ctaataatgt tacatctggt tggtctttag atgttaaggc
    69961 tgcctgtagt tttgttgcat tttcatagta atctttctgt tttaacatat ttacttgtac
    70021 atccttatgt tcactattaa attggtcaac cattttttga gcagtttctc cattagttcc
    70081 acctaaagga gcccagaaat ctatcttcgt aatattgcta tcagtctttt ctcctttaga
    70141 tgcatttgca tcattagaat ttgaacaccc aactaaagaa cataataata atgttattgc
    70201 taatcctgtt gctaattttc ttttaagctt cattttcatc ctccaaattt agtctttaat
    70261 tttttatttt attcctgaat acataaaagc ttcttttact tttttattcg caaatatata
    70321 aacaagaatt attggtaaaa ttagaattat atttcctgcc attattacat tccatgcagt
    70381 aattccttct gaagatttaa ggagcgcaac tcctattggt aaagttctta ttgcatctgt
    70441 atttgtcatt actaagggcc agaaataatt attccaatgg tatataaaat taaataatat
    70501 aaatgttatt actgctggtt ttgccatagg aaccattatt ctaaacatta tttttaagtc
    70561 agaagcatta tctagtttag ctgcttcaat aatttcatct gaaatctgca taaaattctg
    70621 tctaagcaga aatatcccaa atgaagatgt cataaatgga attataagtg gaacataagt
    70681 atttataaat ccaaacttac tcatcatcat atagactggt agaaaagtta cttgtggtgg
    70741 aatcataagt cctacaagca aaagcccaaa tagcattttt tcacctttaa atttaatctt
    70801 agaaaatgca tatgctgctg gaaccataac taaaaattgt acaattaaaa cacttcctgt
    70861 tacaaataca ctgtttagca aatatctaaa aaatggacct gaatgccatg ctgtactata
    70921 attttctaac actatatcat ttggtataat agtgggcggt aattgcatca tttcttgtgg
    70981 atttttaaag gatgtagata gcatccatat aaaagggaat ataaatattg cagataaaag
    71041 taatagaatt aatatttcta ttgattttga tgctattttt tttatatcaa ctttgtcttt
    71101 tttgataggt tgtataatat ccattgtctc ctccttttgg ataaacctta taatatctac
    71161 tttttcttta ttgataatga actttctttg ataagagtct aaagttagca tatgtagcaa
    71221 tcataactat agctaacaaa aacatactcg ctgcactcgc ttgccctatg tcatagtata
    71281 taaatccaga ctcatatata taataagata acatgttagt tgaacccact ggcccacctt
    71341 gtgtcattat acttatctca tcaaatactt gaaaagatgc agttgttgtt gttatcataa
    71401 gaaaaaatat tgttggtgat aatagtggca atgtcacttt aaagaaattc gttattttgt
    71461 ttgcattatc taatttagat gcttcatata tatagtttgg tatggattta agacctgata
    71521 acactattaa gatattatat ccaagagtct tccatattcc tattagaatt agtgacatta
    71581 aagctgaact ttcacttgaa agccactttg atgttggtaa atgtaatgtc gatagtatcc
    71641 agtttaaaaa gccatattgt ggctccataa tccaaagcca caatacagct acagatacta
    71701 gtgaaattac atgtggtgta aagattatac tttgcgttaa attgtgtatt atagaatttt
    71761 tatttagcca aacagcaagt actatggcta gtgatataga tatagtcacc ataaaaaaag
    71821 tataaattgc agtgtttgtt atagtttgta taaactctgg attctttaaa agttctgtat
    71881 aattgtttaa gcctacattt tcaaaggttg aactaagaag actaccagat ttgaagctta
    71941 gagatatcgt cttaattatt ggatagacta taaacaataa agttcctata atagcaggtg
    72001 ttatatataa atatgcttta ttaaattgct ttttcataaa tatctccttt gattttagaa
    72061 tacatacttt tacatacttt tacatcttct attctttctc catttttatc aaaataatat
    72121 aaatcttttt ctaatacact tattcttaaa gttcttccaa tatcaaatat atcattttcc
    72181 gttttgactc ttatctctct attaagaaca gataaacaat atatagtttc atttcccaac
    72241 acttctttag ttacaacttt tccaaataga ctaaatacat catcattttt cccatctatg
    72301 tttatactct ctagtgttgc tttttctggt ctgaatccaa atttaatatc attttttata
    72361 tctagtatgt tcatacaagg actccctata aattgagcta caaataaatt tttaggattt
    72421 tgatatatct tctttggaga acctatttgc attatctttc ctttgttcat tataactatc
    72481 ttatctgcca ttgacattgc ctcaacctgg tcatgagtta cataaacaaa tgtagacttt
    72541 agtttttgat gtaattgtat taattctgtt ctcatttgat ttcttaattt agcatctaaa
    72601 tttgacaatg gttcatccat taaaaatacc tttggatttt taaccatagc tctagcaagt
    72661 gccactcttt gtctttgacc tccagataag ttgcctggtt tcacatttaa atattctctc
    72721 aatcctacta catcaataac ttctgttata agtttttctc ttttttcttt ttctactttt
    72781 ttgtttttaa gaccaaattc tatgttttct ctaacagtca tatgtggata taatgcataa
    72841 ttttgaaata ccatagctat atccctttta ctagcatccg tttttgtaac atcattttct
    72901 tcaatcttca acctacctga agttatatct tcaagacctg caatcattct taacgtagta
    72961 gatttaccac atccacttgg gcctaccaat actgtaaaag aaccatcttc tatagtaaga
    73021 tttaaatttt ctataactgt atttttttta ttataagatt ttgttacatt ttctagtctt
    73081 atatctgcca tttttatcct cccaaaatat ttaatttaat tctacgattt acttatagat
    73141 taataatact cttaatttgt aaaggatata ttaagacaaa gtgaatatat ggtaaactta
    73201 ttaaaataaa ggttaaatta taaacatttt ttgttaaata tactgaagtt aagatgatat
    73261 acagcttatg ttagctataa ttttctatat ttttcatatt catggtttgc tatcacaatg
    73321 taattttaat ttatgaagag tcatataaaa ctatttattt tttatataat ttggtttgaa
    73381 agtaaaaaag acctctatgg gggatagagg tctttaagtg ggggagattg agtaatttat
    73441 ttttgctata ttaagtttta caattatatt atgtcccaaa tttacaaggt ttaaacataa
    73501 aaaataaaaa ttttttaatt tttataaatt tacccaaaaa a
//
LOCUS       DAMJWC010000010        71391 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMJWC010000010 DAMJWC010000000
VERSION     DAMJWC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.010"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            168..1229
                     /locus_tag="PC503_000841"
     CDS             168..1229
                     /locus_tag="PC503_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF2526855.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEISKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            1320..2933
                     /locus_tag="PC503_000842"
     CDS             1320..2933
                     /locus_tag="PC503_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2526856.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            3208..5193
                     /locus_tag="PC503_000843"
     CDS             3208..5193
                     /locus_tag="PC503_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2526857.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            5198..5632
                     /locus_tag="PC503_000844"
     CDS             5198..5632
                     /locus_tag="PC503_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF2526858.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKNLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            5661..6221
                     /gene="srlA"
                     /locus_tag="PC503_000845"
     CDS             5661..6221
                     /gene="srlA"
                     /locus_tag="PC503_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2526859.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            6285..6653
                     /locus_tag="PC503_000846"
     CDS             6285..6653
                     /locus_tag="PC503_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF2526860.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            6678..7244
                     /locus_tag="PC503_000847"
     CDS             6678..7244
                     /locus_tag="PC503_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2526861.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            7285..7650
                     /locus_tag="PC503_000848"
     CDS             7285..7650
                     /locus_tag="PC503_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2526862.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            7751..8524
                     /gene="srlD"
                     /locus_tag="PC503_000849"
     CDS             7751..8524
                     /gene="srlD"
                     /locus_tag="PC503_000849"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF2526863.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            8873..11017
                     /locus_tag="PC503_000850"
     CDS             8873..11017
                     /locus_tag="PC503_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2526864.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            11105..11440
                     /gene="spoIIAA"
                     /locus_tag="PC503_000851"
     CDS             11105..11440
                     /gene="spoIIAA"
                     /locus_tag="PC503_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF2526865.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            11454..11882
                     /locus_tag="PC503_000852"
     CDS             11454..11882
                     /locus_tag="PC503_000852"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF2526866.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            11905..12669
                     /gene="sigF"
                     /locus_tag="PC503_000853"
     CDS             11905..12669
                     /gene="sigF"
                     /locus_tag="PC503_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF2526867.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAIKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            12949..13386
                     /gene="spoVAC"
                     /locus_tag="PC503_000854"
     CDS             12949..13386
                     /gene="spoVAC"
                     /locus_tag="PC503_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF2526868.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            13553..14566
                     /gene="spoVAD"
                     /locus_tag="PC503_000855"
     CDS             13553..14566
                     /gene="spoVAD"
                     /locus_tag="PC503_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF2526869.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            14580..14942
                     /gene="spoVAE"
                     /locus_tag="PC503_000856"
     CDS             14580..14942
                     /gene="spoVAE"
                     /locus_tag="PC503_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF2526870.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            15125..16141
                     /locus_tag="PC503_000857"
     CDS             15125..16141
                     /locus_tag="PC503_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2526871.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            16516..17358
                     /locus_tag="PC503_000858"
     CDS             16516..17358
                     /locus_tag="PC503_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2526872.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            17373..17837
                     /locus_tag="PC503_000859"
     CDS             17373..17837
                     /locus_tag="PC503_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526873.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            17824..18996
                     /locus_tag="PC503_000860"
     CDS             17824..18996
                     /locus_tag="PC503_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2526874.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            19040..19975
                     /locus_tag="PC503_000861"
     CDS             19040..19975
                     /locus_tag="PC503_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF2526875.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(20249..22942)
                     /locus_tag="PC503_000862"
     CDS             complement(20249..22942)
                     /locus_tag="PC503_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2526876.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            23156..23854
                     /gene="yunB"
                     /locus_tag="PC503_000863"
     CDS             23156..23854
                     /gene="yunB"
                     /locus_tag="PC503_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2526877.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(24066..25073)
                     /locus_tag="PC503_000864"
     CDS             complement(24066..25073)
                     /locus_tag="PC503_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2526878.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            25301..26185
                     /locus_tag="PC503_000865"
     CDS             25301..26185
                     /locus_tag="PC503_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2526879.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            26387..27937
                     /locus_tag="PC503_000866"
     CDS             26387..27937
                     /locus_tag="PC503_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2526880.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            27966..28613
                     /locus_tag="PC503_000867"
     CDS             27966..28613
                     /locus_tag="PC503_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF2526881.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(28755..29015)
                     /locus_tag="PC503_000868"
     CDS             complement(28755..29015)
                     /locus_tag="PC503_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2526882.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            29232..30515
                     /gene="hflX"
                     /locus_tag="PC503_000869"
     CDS             29232..30515
                     /gene="hflX"
                     /locus_tag="PC503_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2526883.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            30523..31200
                     /locus_tag="PC503_000870"
     CDS             30523..31200
                     /locus_tag="PC503_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2526884.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            31286..31729
                     /locus_tag="PC503_000871"
     CDS             31286..31729
                     /locus_tag="PC503_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2526885.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            32034..32678
                     /locus_tag="PC503_000872"
     CDS             32034..32678
                     /locus_tag="PC503_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2526886.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(32764..33141)
                     /locus_tag="PC503_000873"
     CDS             complement(32764..33141)
                     /locus_tag="PC503_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2526887.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(33141..33527)
                     /locus_tag="PC503_000874"
     CDS             complement(33141..33527)
                     /locus_tag="PC503_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2526888.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            33706..34461
                     /gene="nadE"
                     /locus_tag="PC503_000875"
     CDS             33706..34461
                     /gene="nadE"
                     /locus_tag="PC503_000875"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2526889.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            34544..35263
                     /locus_tag="PC503_000876"
     CDS             34544..35263
                     /locus_tag="PC503_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2526890.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(35430..36434)
                     /locus_tag="PC503_000877"
     CDS             complement(35430..36434)
                     /locus_tag="PC503_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2526891.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            36700..37596
                     /locus_tag="PC503_000878"
     CDS             36700..37596
                     /locus_tag="PC503_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2526892.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            37717..38979
                     /locus_tag="PC503_000879"
     CDS             37717..38979
                     /locus_tag="PC503_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526893.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            39055..40248
                     /locus_tag="PC503_000880"
     CDS             39055..40248
                     /locus_tag="PC503_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2526894.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            40877..41671
                     /locus_tag="PC503_000881"
     CDS             40877..41671
                     /locus_tag="PC503_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2526895.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDVAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            41766..43106
                     /locus_tag="PC503_000882"
     CDS             41766..43106
                     /locus_tag="PC503_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2526896.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            43243..44475
                     /locus_tag="PC503_000883"
     CDS             43243..44475
                     /locus_tag="PC503_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2526897.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            44515..45657
                     /locus_tag="PC503_000884"
     CDS             44515..45657
                     /locus_tag="PC503_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2526898.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            45668..46462
                     /locus_tag="PC503_000885"
     CDS             45668..46462
                     /locus_tag="PC503_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2526899.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            46473..47495
                     /locus_tag="PC503_000886"
     CDS             46473..47495
                     /locus_tag="PC503_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2526900.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TIRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            47594..48970
                     /locus_tag="PC503_000887"
     CDS             47594..48970
                     /locus_tag="PC503_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2526901.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(49302..49646)
                     /locus_tag="PC503_000888"
     CDS             complement(49302..49646)
                     /locus_tag="PC503_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526902.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            50134..51144
                     /locus_tag="PC503_000889"
     CDS             50134..51144
                     /locus_tag="PC503_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2526903.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            51280..51768
                     /locus_tag="PC503_000890"
     CDS             51280..51768
                     /locus_tag="PC503_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2526904.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            51944..53872
                     /locus_tag="PC503_000891"
     CDS             51944..53872
                     /locus_tag="PC503_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2526905.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            54049..54459
                     /locus_tag="PC503_000892"
     CDS             54049..54459
                     /locus_tag="PC503_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2526906.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            54481..54783
                     /locus_tag="PC503_000893"
     CDS             54481..54783
                     /locus_tag="PC503_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2526907.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(55000..55692)
                     /locus_tag="PC503_000894"
     CDS             complement(55000..55692)
                     /locus_tag="PC503_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2526908.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(55718..56905)
                     /locus_tag="PC503_000895"
     CDS             complement(55718..56905)
                     /locus_tag="PC503_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2526909.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            57241..59118
                     /locus_tag="PC503_000896"
     CDS             57241..59118
                     /locus_tag="PC503_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2526910.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMTDSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            59475..60881
                     /locus_tag="PC503_000897"
     CDS             59475..60881
                     /locus_tag="PC503_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2526911.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            60909..61757
                     /locus_tag="PC503_000898"
     CDS             60909..61757
                     /locus_tag="PC503_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2526912.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            62418..63110
                     /locus_tag="PC503_000899"
     CDS             62418..63110
                     /locus_tag="PC503_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2526913.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            63107..64042
                     /locus_tag="PC503_000900"
     CDS             63107..64042
                     /locus_tag="PC503_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2526914.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            64190..65113
                     /locus_tag="PC503_000901"
     CDS             64190..65113
                     /locus_tag="PC503_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2526915.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            65097..65867
                     /locus_tag="PC503_000902"
     CDS             65097..65867
                     /locus_tag="PC503_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526916.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            65877..66659
                     /locus_tag="PC503_000903"
     CDS             65877..66659
                     /locus_tag="PC503_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2526917.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            67036..67572
                     /locus_tag="PC503_000904"
     CDS             67036..67572
                     /locus_tag="PC503_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2526918.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            67604..67993
                     /locus_tag="PC503_000905"
     CDS             67604..67993
                     /locus_tag="PC503_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2526919.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            68030..68416
                     /locus_tag="PC503_000906"
     CDS             68030..68416
                     /locus_tag="PC503_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2526920.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            68543..69985
                     /locus_tag="PC503_000907"
     CDS             68543..69985
                     /locus_tag="PC503_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2526921.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            70282..71097
                     /locus_tag="PC503_000908"
     CDS             70282..71097
                     /locus_tag="PC503_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2526922.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT        26937 a         8258 c        13091 g        23105 t
ORIGIN      
        1 atcctgtata cataaaaaat aaaaaattgt cgctttaaag tataaaacag attatatgtt
       61 aataatgtgg tgaaattata cccatatata aataaaataa aacaaataaa tagctaatta
      121 aggagaaaat attttttatt ttttgtttag gataaataaa ttttattatg gaaaaaagaa
      181 aaagcataca tcttcacaaa ctgaatattt atttaatagg gggaggtgat agattgttta
      241 tcacagtggt attattttta gtaggtttcc tattaattac taaaggcgca gatatcttta
      301 taaattgtac tgtagagata agtaaaaaaa cgaatatatc agaaattata cttggagcta
      361 ctatagttag ttttgcaaca acattacctg agtttacagt gtctctactt gcttctattg
      421 atggtcatac tactatgagt ttaggaaatg cagttggttc tataatatgt aatacagggt
      481 tagcattagg gttggttgtt tttataagtc catttaatgt agataaaaaa atgttttttt
      541 ctaagtcttt actattaata gtatccgtta tagttttaat tttattgagt ttagatggag
      601 ttataacaag aggtgattca ttattactta taataatatt aatcttttat atggttaata
      661 attatagaag tgtcgttgga aaatctgata ctaaaaatag aaatattaaa aataacacta
      721 ttaaagacat atctactaaa aaagggaaaa attatagagg tttttccgta ttagaaattg
      781 taaaaatact attacttttt gctacaggat tgataatgat gataataggt tcacaaatcc
      841 ttatagagag tggagtaata atagctagtt ttttaaatat acctcaaggt atagtaagtt
      901 taactataat agcacttgga acttctctgc cagagatagt ttcgtcgatt actgctataa
      961 gaaaaaatca tcatgaaata tcagtaggaa atattttggg tgcaaacata ttgaatatag
     1021 tatcagtaat agctgtatca gcaataccaa ataacatacc aatactatct caaaatagac
     1081 aattggatat accattcatg atattattat tattaatagt aataatacca acacttaaat
     1141 ctaataaact tagtagaata caaggtatat tgatgttatt cacatatttt ctgtacatat
     1201 caattttgta tttcatgtat attatttaac tatactgttt aaaatattaa ttgcagaata
     1261 tcctaaaaaa gtatataatg gataggttaa gattaattga taacggagag gaataatata
     1321 tgaatataac aaagtttgaa gatttaccaa taagtgaggg aataaaaaaa gctatagctg
     1381 aaatggggtt tgaagaacca tctcctatac aagcacagtc tatacctgcg attttgtcag
     1441 gtaaagacgt tataggacaa gctcaaactg gtacgggaaa aacagctgct tttagtatcc
     1501 ctatactaga aacaatagac ccaaataata gaagtttaca agctgtagtg ctttgtccaa
     1561 caagagaact ggcaatacaa gtatcaacag aaataagaaa gttagctaag tattcgcacg
     1621 gaataaagac attacctata tatggtggtc agccaataga tagacaaata aaatctctaa
     1681 agagtggtgt gcaagttgta ataggtacac caggacgtac aatagaccat atcaatcgta
     1741 aaacattaaa gatggataat gtaaaaatga ttatattaga tgaagcagat gaaatgctag
     1801 atatgggatt tagagaagat atagaaatga ttttaagtaa gattccagaa gaaagacaaa
     1861 caactttctt ttcagctact atgccaagag gaattttgga attaactaag agatatcaaa
     1921 aagacccaga gcatataaaa gttgttagaa aagaacttac agtttcaaat acaaagcaat
     1981 actatataga aactaggtca tcaaataaat tagaagtatt atgtagatta gtagatgtat
     2041 atgaccctaa actatctgtt gttttctgta atactaagag aaaagcagac gaattggtag
     2101 gagatttaca agcaagagga tattttgcag atgcattaca tggtgactta aaacagactc
     2161 aaagagatat agtaatggat aagtttagaa atggtacaat agatatactt gttgctactg
     2221 atgttgcagc tagaggtata gatgttgatg atgttgaatg tgtattcaac tatgacttac
     2281 cacaagatga agaatattac gttcatagaa ttggtagaac tggtcgtgct ggtagagaag
     2341 gtatgtcatt tacttttgta tttggaaaag aaatgagaaa gatgaaagat atagaaagat
     2401 atactaaatc taaactaata aagcataata taccaacaat aactgatgtt gaagagaaaa
     2461 aagtaggtac tttctttgca caagttaaac aaactataga agaaggtcac ttaactaaac
     2521 aattacaatg gttagaaggt ttctgtaatg atgaagatta tgcaatggtt gatatagctg
     2581 ctgcacttgt aaaactatct ctaggtgaag aaatgaaaga agaaataata gaagaaaaac
     2641 ctagaagaga gcgtggagat agaaaaggtg gtactggagc taaagatggt atgattagat
     2701 tatttatcaa tattggtaga aatcaaagag tacaagcaaa agatatagtt ggtgccatag
     2761 ctggagaagt tggaatacca ggtaaagtag taggtactat agatatatat gataagtata
     2821 cttttgttga aatacctaaa aaagatgcaa aaacagtaat tgaaaagatg aaagatatta
     2881 agataaaagg taataagatt aatatagaaa aagcaaataa gaagaaaaaa taacgtatag
     2941 tatacaaaac tataattaga aaatatataa aataatatat tggatattta aaaagcctga
     3001 tgtgttttca aaacagatag tagataatct gtaagagtta acagcataag gcttttcttg
     3061 ttttatatga tgttataatt ttccagattg ttgtgaaaaa tgtatattag ttcctttttt
     3121 tcaaatctga tttgaaaaag agaatattaa ttatctatat agtttagatt ataataaaaa
     3181 atgtaagata acaaagggga gaaaaagatg tcaatgactt atatggaccc tagggttttt
     3241 ttgattttag aaatggtgtt agaagaagac acaaatactc tagaacaatt ttcaaatgtt
     3301 ttgggtgtta gtactaggac tatcagaaac tatataaacc agattaatcg agaattaaaa
     3361 ggtggtattg ctaaaatagt taaaaatgaa aaaggtacat atagtataag aattgaggat
     3421 gaaagtaaat taattgagat tgtaaatttt aatagaggaa agctatcaaa ttttataaat
     3481 ttaaattcac ctgatgaaag aataaattat gttcttgata ttttaactat gaccaacaat
     3541 ccaattacca tagatgattt ggctgaagag atatgtatag gaagaacaac attaataaag
     3601 gatttaaaaa aagcagacag aattttagct gaatatgatt tagaattaaa aaggaagcca
     3661 aatataggta tgattttagt tggtgaagaa atggatataa gattattaat ccttgataga
     3721 ttgtatgaaa attatattga tgtcttggaa aacgttaatc agataaattt agttaaagat
     3781 tatgatattg aatgtcttag agatgaatta aaaaagttat ttaaaaaaga agaactctac
     3841 ataacagaac aggtcttgag agatgttgaa agatatataa tcatgtctgt cttaagaaat
     3901 ctaaatgggt acaaatttga aaagatagat aagagatttg aagtgataag atgttcagat
     3961 gaatatactt taggattaaa gctcaaagct ttattggaaa agatatttaa tatagtttta
     4021 aatgaaaaag aaaccatatt tttgacaatg ccattaatag gtagaaaagc tcctagtaca
     4081 aaattagcac ttagcagtat aaagataaat gatagcgtaa aggaagttgt agatgaagta
     4141 actagttttt tattagagac ctcagggatt gattttaaag aagataaaaa gcttatagaa
     4201 aatttggaat atcacttgta ttttgcactt aatagaatga gattcaacat aagggtaaaa
     4261 aatcctcttt tacaagaaat aaaggaaaga tatacatttc catatagtgt tgcaaagata
     4321 gctgcaatga taattgagga aaagtttgac ttgaaaatat gtgaccacga aataggatat
     4381 atagcattac attttggaag ttattttgaa aaaaattcaa gaaaagttct aaatgtaaat
     4441 agggtagctg ttgtttgtgg aacaggtctt gggactgcac aacttattag aataaagata
     4501 ggaaaaatac ttggagaaag tgtagaagta aatacttttt ctgatataga agctaaagct
     4561 aatttagatt tattaaagta ttatgattta gtatttacaa cagtagattt caaaacagac
     4621 ttagatgttc caatttttag agtaaatgcg ttatttaatg aagaaagtat aaagaaagag
     4681 atagaaaatg caatactttt gaaaaatagt ataaatctta agtctataaa aaagattgaa
     4741 aaaaatatcc cttttatagg taaattaatt gaagaggata agttctttat attgaataag
     4801 agtacgttta tggaaaattt agaagatatg ttagaaaaat tagttcataa aggaattatt
     4861 gatatagagt tcaaaaaaaa ggtattaaaa agagaaaaga aatcttcaac agcattagat
     4921 aattatatag cattgcctca ctcagttaat actaatgggg aaaatcttta tctggcattt
     4981 ggaatattag aaaaaccagt gatttgggat acaaaggaaa ttagaataat aatattgatg
     5041 ataattccag ataagaatgt agatagtaca gacctgataa taaaaagtta tgaagaagta
     5101 cttgaagtag ggagagataa aaagatggta gaagaacttg ctaaggcaaa atcatttgat
     5161 gaattttata aaataattac caagaggagg taataatatg gacccagtaa tttttattat
     5221 agcatcactt attacagtgt atttattaaa tatttttctt ggatacttac agcttaaaga
     5281 ttttaataaa aattatattg aactaaaaag aaaaggaaga gtggcaattg gcagaaaaaa
     5341 aggaagaatt tcatcgggta caattgtgtt gatacttata aatgatgatg gtgtgattgt
     5401 cgagactaga aaaatgcaag gtgttacagt attggcaaga gtaaagtcat ttgaaggttt
     5461 ggtaggaaag aacttagagt atatagaaaa atcagattta actgtttaca ataaactact
     5521 taaaaaagca atactagatg cagtcaaaca gtacataaca tttgagaaaa ataaatgtga
     5581 agatacaaat aatctgagta ctgatgaaga gtgtaggatg gaagtagttt aaaaaaatat
     5641 atttataagg aggagttaat atgacgcaat tttttcaagt attagcaagt ggtgcagata
     5701 gttttatgaa tttatttagg gcaggtgggc aacaatttgt aggttttgta acagatatag
     5761 taccactttt agtagcatta ttagttacaa tgaatgcaat tatcaacttt attggtacag
     5821 atagagtcga gagacttgca aaaaaatgtt ctgcaaatat atttactaga tatttgatat
     5881 taccagtcct tggtacattt gtatttgcaa acccaatgac actatcatta ggaagattct
     5941 tgccagaaaa gtttaaacct agttactttg cagcagcaag cttttcatgc catacaatga
     6001 atggattatt cccacatatc aatccaggtg aactatttat atatctagga attgcaaatg
     6061 gtataacaac tttgggattc tcaacagcag atttagcagt tagatatttg ttagtgggta
     6121 tagttgcaaa ctttattaaa ggtgtagtta ctgactatac aacaaaattt gtagagaaac
     6181 aacaaggaat agcattaaat tcagatataa agattggata attactttaa ggtataaata
     6241 aatttttcaa ataaaaagat agtgtataga ggaggataaa ttatatggca tttaacaaag
     6301 ttaaaatagt aaaaggttct ggaggatggg gtggaccatt gataatagaa ccaacagaaa
     6361 agaagaataa ggtagtatat gtgactgggg gagcaaagcc agaaactgca gtaaaaatag
     6421 ctgaacttac aggatgtgag ttaatagatg gattttcaca gggtgttaaa gatgatgaaa
     6481 tcgcatgtgt aataataaat tgtggtggaa cattgagatg tggtatatat cctcaaaaga
     6541 aaataccgac tataaatata atgaaaacag gaaaaagtgg accattagca atgtttataa
     6601 aagaagatat atatgtttca ggggtaaaac caacaaatgt agagcagtta taattgaggt
     6661 agtaggaggg aagaaatatg gcttatgata ctaaaaagaa gataagtgag cagagtcaag
     6721 gaattgttgc aaaaataggt atagcactag gaaatgtgac aagtactctt tttcaagctg
     6781 gtagggatac tatagataca ttaatacata ctatactgcc ttttatggct ttcgttgcag
     6841 tcctaatagg tataataaat caatcaggta taggaaattg ggtagccaat ttacttactc
     6901 cattaatcgg aaatgttgga ggtttagttg tcttatcaat aatatgttca tttccgttgt
     6961 tgtctccgtt tcttggacca ggagctgtta tagctcagat agtgggagta ttggttggta
     7021 cagaaatagg aaaaggaaat attccaccaa gtttagcatt accagcattg tttgcaataa
     7081 actcacaagc agcttgtgac tttataccag taggtcttgg tcttgcagaa gctgaacctg
     7141 atacagttca agtaggagtt ccgtcagttt tatattctag atttttaaca ggtgcaccaa
     7201 ctgttctatt agcatggtta gcaagctttg ggttatataa atagaagaat actttataaa
     7261 taattagaga gaggttcagt tgatatggaa ttaatataca gtactcaaat aaataaaata
     7321 ggagataatg caaatgaatt tttacaacat aatatgtttg taactttcaa agataatgct
     7381 cctcaagagt tagaaaatta ctgttatata cattctgaaa ataatttagt aaaagaaata
     7441 cttacggatg atgtgctatc aataaataat gttgattaca aaattacttc tgttggtgag
     7501 ttagtaaacc aaaatctttc agaattaggt catataacat ttaagtttac aggtgaaaaa
     7561 gatggagcaa ttggaggaac cttatatctt gaagaaaaag aaatagcacc tattggcgta
     7621 ggtactatac taaaaataat tagaaaataa aatttaaaac gaatctaatc atattataag
     7681 taaattatag ataaaagtca atttaactaa tcaagttaac ttttaatgtg ataaaaaagg
     7741 ggaaatgaaa atgagaaaag tggctttagt cgttggagga ggaagaagtt taggtgaata
     7801 tttatctaaa catttagcta aagtaggtta tgatgttgct attgcagatt taaatgaaga
     7861 caacgcaaaa aaagtagctg aagaaataaa aactgaattt ggttgtaaat ctgtaggata
     7921 tagttgtaat gccatagatg aaagacaggt tataagtact gtcaaagcta ttgaaaatga
     7981 ttttgataga atagatttat tagtgtacaa tgcaggagtg gctgtaagta aaaaaataac
     8041 tgattttgga tacaaagatt ttaaatttat tgtagacgta aatttaaatg ggtactttct
     8101 atttgcaaga gaagtatcta aagtcatgat agcaaaaggt attgagggta gaataataca
     8161 gataaattca aaatcaggta gagtgggaag caagcataat tcaggatatt cagcaggtaa
     8221 atttgctgga gtaggactta ctcaaagttt agcgctagat ttggcagaac ataagataac
     8281 tgtaaatgca ctgatgctcg gtaatttact tgattctgat atgtttgaaa gtttaattcc
     8341 tcaatatgca gtaaaattgg gaatacctga atcagaagtc aagcaagttt atatagataa
     8401 agtaccttta aaaagagggt gtagatttat agatgttgca aatatgctta cattttatgc
     8461 ttcaaaggaa gctgaatact gcactggtca atctataaat attactggtg gacaagttat
     8521 gtaaggtttt tatggagtgt ctcaagatga actctttagt tcatgaggca cttttttgta
     8581 taaaattaaa tatattttca gcatttaaac aatgaaaaag aggtttatct ttattttgag
     8641 atagcctcat ttttgtaatt aaaaaacata gtgtttaagt aaacatataa gattgttagt
     8701 tttttaaaag agaatttttt aataatatta tatttatgaa gtatttttaa acttattttg
     8761 ataaaatata gctatgtttt atatactgta gttttgaaca tagaaagttt aataaattat
     8821 agtatatatg ttaattttta ataaggtaag aaagtagaaa gaaggatatt ttatggatat
     8881 aataaaaaaa ttaagtcatg ggtgtacatt agattgtcat gactgttgta aattcaatgt
     8941 ttatactaaa ggaaataatg tagtaaaaat tgaaggagat aaaaatcatc cttatacaaa
     9001 aggttttata tgcaaaaaag ggatggccca tttagataga ttaaatcata aagatagaat
     9061 aaagactcct atgcttaaag ttgatggagt atggaaagag atttcttttg ataaagctat
     9121 agaaataatg gcagaaaagc ttacatacta taaagaaaag tatacatcaa agtctgtcat
     9181 gcattatgac caatatggaa gtgggtctgt gctaaaatac ataggagata tattttttaa
     9241 tttttatgga ggtgttagca gacataaagg tggtccctgt tggagtgcag ggatgcatgc
     9301 tcaaaaatat gattttggag tagctaagag tcatgctata gaagatatgt taaatagtaa
     9361 aagtatattt gtgtggggaa aaaatccagc atatactaca attcatacta tgcaaataat
     9421 taaaaaagct aaagaaaaag ggataaagat agtagtgatt gaccccatat atacaaaaac
     9481 agctcaaata gcagataagt atgtacaagt aaatcctgga acagatggag ctttagctat
     9541 agctatggca aaaattatag tagaagataa attatatgat gaagaatata taaactcgta
     9601 tgttattggt tttgaagaat ataaaaaata tttatcttca ttggaattaa gttttttaat
     9661 tgatgaatgt ggtgttaaag agaatgatat aagagagtta gtggatttat atactaacaa
     9721 atattcaagt ataaatgttg gatatgggct tcaaaaatat aaaaatggtg gaaacacaat
     9781 aagagcaata gatgctttag gtgctataac tggtcaaata ggatttagtg gtggaggggt
     9841 aaactatgct aataaagttt atccgagtgt tataaattct gacccttaca atagccaatc
     9901 atatggtgaa gatagggagt tttatgtaag taatatcagt aaatttatag aagaatcttt
     9961 aaaaaataca tcaaataaag taaattatgc atcagatgaa cttgatatga catcaaataa
    10021 agtaaattat gtatcagatg aacttgatat aacatcaaat aaaacagatt atatatcaaa
    10081 tgaattgtat aatttatcta ataagtcaat caaaggtaat attcctataa agatggctgt
    10141 aataactaaa agtaatatgc tgaatcaact gccagattta gtagaattgg agagggtgtt
    10201 ttcaaaaatt gaatttaaag tatgttttga tatgtttata actgatacag ctactttatg
    10261 tgacatgttt ataccgtgta caaatacact agagagtgaa gatataattt atagctcaat
    10321 gaccaatcca tatataacct ataatgaaag agctgtaaag ccagcacata aattgatgga
    10381 tgaatattac ttctttatgg agctagctaa aaagatggga ttaaatgatt atccttttgt
    10441 agaaaagaga acttatttag aaaaagtgat tgaaccactt aagcgttttg acaaaaatct
    10501 ggatatagaa aaacttaaaa acaattactt tactatacat aaccctgttg cttgggaaga
    10561 taagaagttt gagactccat ctggaaaata cgagctttat tcagaaagta taaaaaactt
    10621 gggaataagt ccaacacctg tatatataag caataaatat aaagaaatag aagataaaaa
    10681 tatttctttt agattattaa ctaatcatca tgcagatact ttatttagtc agcattttat
    10741 ggacaaaaaa tctatagctc aagcatatat aaatcggaga atggctaaaa aagtaggtat
    10801 tgaggacaaa gatattgtga tattgaggtc aaaaaaagca aaaataaatg tacaaataaa
    10861 tatagatgat ggagtaggta attatatagt aaaaatgtat gttggttggt ggaagaaaca
    10921 tggaaatcct aatagtttaa cagacactgg tatatcagat tttgggggtc aggtaacata
    10981 taatgaaagt atggtagaaa taatacgaca aaactagtta aatttcattg aaggaataaa
    11041 aatataatta tagaattgat taaaagttac tatttttaca aaactattga aggagggatt
    11101 tttgatggta aattattcct tagaacataa gaatctatac atagaattta tgtgctcaga
    11161 actagaccac catgtagcca atgaaataag ggaagaaata gataacttat taagtgtaaa
    11221 tcaagtaaaa aatgttgtat ttaattttga aaatattaat tttatggatt cttcaggtat
    11281 aggcgtcatc ataggtagat ataaaaagat ttctaatgaa gggggacgag tttcagtaat
    11341 taatataagt tcacgagtta agaagatttt tgatttatct gggttaaata aaattattgg
    11401 catttatgat acgtatgaag aagctctaag ttctttgtag ggaggagtat gtgatgaata
    11461 atattatgga agttaaattt tcggcaatat ctgaaaatga aagtttagca agagttatag
    11521 tagcatcctt tgcagctaag ttagacccaa cagtagatga gttagtagat ataaaaactg
    11581 ctgtctctga ggctgttacg aatgctataa tacatggata tgaagaagac agttctaagt
    11641 ttgttttctt aagatgtgag atagaaggaa atactataaa gattatagtt gaagatgaag
    11701 ggtatggaat agaaaatgtg gagaaggcaa tggaaccact ttatacatca aaaccagaac
    11761 ttgatagatc aggaatggga ttcacagtaa tgaaaagctt tatggacgat gtagaggtaa
    11821 gttctgtaaa agataatggg actagaattg aaatgactaa aaaaataaat gtgcctaaat
    11881 aaagtccaaa agtgaggttt tattatggaa gtaactgttg ccagagaaga aaaaaaacct
    11941 cttcttagtc atgaagagac tctagaactt attgaaaaag ttcaaaatgg agatgaagag
    12001 gcaaaagaaa tattaatatc aagcaattta ggtctagtta ggagcgttgt atctagattt
    12061 ttaaatatag gatatgatag agaagattta tttcagttag gttctatagg cttaataaaa
    12121 tcaatatata aatttgaccc aaaatttaat gtaaaattct ctacttatgc agtaccaatg
    12181 attttaggtg aaataaagag atacttaaga gatgatggta tgataaaagt atcaaggtcg
    12241 ttaaagcaaa tagctataaa ggcaaagatg gaaagtgaag ctttaactaa aaaattaggt
    12301 agagagccga gtatagaaga attagctaaa gcaatagatg tagaaaaaga agatttagta
    12361 atggctatgg aagctaattt caatgttgag tatttgcaag gagttattca tgaagaggaa
    12421 ggttctccaa tatgccttat tgataaaata agcatgaaag gagaaagtga agaagaaaaa
    12481 gtagtggata acatattgtt aaaagacata cttggaagac tggataagag agagcgtcaa
    12541 ataatagttc tcagatactt tgaagacatg actcaaagtg aaataggaga gatgctcaat
    12601 atatcacaag ttcaagtatc taggatagag aagaaagtat tgtctaagtt aaaagaatat
    12661 atatcgtgat aatacttatg atatgtagaa taataaaata taataaatat attactaaaa
    12721 taaaatgtaa taacttttta tgttaagttt ttaaattatt aaaagatatt aaaataataa
    12781 aaagcattaa aaaagtaaaa atataaaaac aaggtgtctt tatggaaaaa tagatttttt
    12841 ctttattagg catctttttt attttttgac caaactttag atagtcaaaa taaataatag
    12901 gtttattttt ttaaaattaa caaataatac tttagagagg tgtttagtat ggataaaaat
    12961 tataaaaaat atgtagacca aataagccca aaacctacat atttaaaaaa ctatacactt
    13021 gcatttattg taggtggaat tatttgtatg atagggcaag caataaatga tttgtatatg
    13081 aaagttggag gtcttgataa actaggtgct agttctgcaa catcaataac attaatattt
    13141 ataggggcat ttttaactgg attaggagtt tacgacctaa taggaaaaag agctggagct
    13201 ggttctataa ttccaataac aggttttgct aactcaatag tatctccagc aatggagtat
    13261 aaaagagaag gctatgtatt aggtgtaggt gcaaacttat ttaaaattgc aggaccagtt
    13321 ttagtttatg ggataggttc ttctatttta tgtggaatta tttattatat ttttaagatg
    13381 ttttagatga tttttattta atttaaattt tattaattat gaagaaggta taaaatctga
    13441 aaatagctac taaagtaact aattgaaaaa taattctgca gatttaatta atatttttaa
    13501 ttaatattaa aaatttgaat agtaaaatgc aaaattaaaa aggtgtgaaa atatgaaaaa
    13561 taaaagaatt ggaaaaagaa cagtcaagtt agaaaataaa ccaaccataa tatcaactgg
    13621 aactatagta ggtcctaagg aaggtgaagg accactaaag gactattttg atatgattat
    13681 gactgacgat ttatatggtg aaaagacttg ggaattagct gaaagtaaaa tggtagagac
    13741 tgcatctcaa caagctatcc aaaaggcagg taaaaaattg tcagatgtaa attatatgct
    13801 aggtggcgat ttaataaatc aaatagttcc agcatccttt gcagcaagag aactggctat
    13861 tccattttta ggtatatatg gagcttgttc tacaatggca gaaggtcttt gtataggttc
    13921 tatgcttata gatggtggtt ttgctgattt agtactgtca ggtacatcaa gtcactattg
    13981 tacagcagaa agacaattta gattcccact tgaacttgga aatcaaaaac caatgacagc
    14041 ccagtggaca gttacaggag caggaagtgt attattagct cctaatggag acggtccaaa
    14101 agtaaagtat gttactgttg gtaaagtaat agatgagggt attgatgatg gtaataatat
    14161 gggaccagct atggctccag cagcaataga tactatctac tcttactttg aagatactaa
    14221 tgatgaccca aatagctttg atataattgc tactggagat ttaggtactc ttggaaaaca
    14281 gatagcagaa gactttctaa aagaaaaagg tgtagatata tcaaaagttt atactgactg
    14341 tggtatagag atgtttaacc ttaaagaaca agatgtccac tgtggtggaa gtggatgtgg
    14401 gtgttcagct acagtgtttg caggatatat atatgataag ttgagaaaaa aagaatttaa
    14461 caaagtaatg cttgtatcaa caggagcact actttcaccg acaagtacac tacaaaagca
    14521 gacaatacca tgtgttgcac atgcagtagt aatagtaaat gagtaggaag tgatataata
    14581 tgttaatgga ctatgtaaga gtatttattg taggtggaat tatatgttta atagcccaag
    14641 taatgatgga ttatttcaaa atgcaaactc catatgttat ggtaacgtat gtaacaactg
    14701 gtgtagtttt aacttttcta ggactttatg agccattagt taagtttgca gcagcaggtg
    14761 caacagttcc tataatagga tttggatatt cacttgctac aggagtaata aaatcaattc
    14821 aaagtgatgg ttttttaggt atttttttag gaggtacaac tgctacagct ggtggaatag
    14881 cagcagctat attctttgga tatattatgt cagtagtatt tactccaaaa gcaaaaccat
    14941 aaatctttat taaaagaata ataagttttt gaaataataa ctttttataa agcaggtgga
    15001 tatcttttag attccacctg ttttttatat aaagaagcgt ttacataatt gaagttgaca
    15061 attatttaca acatagtgta gtattatatt atcaaaataa aatgaagtga agtaggggat
    15121 aaagatggta actattaaag atattgcaag gaatctaggt atcagttatt caactgtttc
    15181 taggtgctta aacaataatc ctaatgtatc tgaaaaaaca aaaaagaaag tggtagaaga
    15241 ggcaaataga ctagggttcc attttaatgt aaatgcaaga aatttagcaa aaaaagaaac
    15301 taacaggata ggggtaatct tttcaaataa ttttaatcat caagatacta gaaagttttt
    15361 tagtgatata atggatagtt ctataaattc tattgagact aataaatacg attttataat
    15421 acagcctaat aataacatta gtggtgatag taatgtatat aaaatggtaa atggacaaat
    15481 ggttgacgga ttagtaattg tgtctcaatc aataaaaaaa gaagagtatg attttttaaa
    15541 agacaataat tttccacatg tatttatata ttttaaacca tcttttatag gagaagtaga
    15601 taatttcttt tgggacgata acgtgtatgg aggttatata gctaccaagc atttaattga
    15661 ccatggtcat aaagatataa taacagtaac ttcagatgat aagagttcaa aaatgcatga
    15721 agatagaacc aagggatatt tgaatgctat ggaagaagca aatttaaaga cagaagtcat
    15781 taaatctaaa atggattttg aatctcaagt tgaattttta gaaaaataca ttgataaaat
    15841 aaaaaaagct tcagctatat ttgtacaaca agatgtacca gcgatttcta taatacaaga
    15901 gttaaaaact acttatggta taaatgtacc agaagatatt tccataatag ggtataataa
    15961 tattgaatta atatcatatt ttaggtcgca tttatcaaca atagatgacc caagagagca
    16021 agttataaaa aatggagtag atagtttagt aaatataata aataaaaaga gtacagaaca
    16081 cattccaaga aaattatatc caaggttaat aatacgaaat agcgttaaaa gaataaagta
    16141 gtaagctttt aagtatcaaa cgtttattaa aaatattata gattatgtga agttttttaa
    16201 caaataatat aaataaaaat taaaaggagt aggtgtatat aagtacattg tactccttta
    16261 tttattgaga tagtttttat aatatgaatg aataatttta ttcaattatt tgaaaatccg
    16321 ttattttaac aatataaatt aataaattat ttgtatttta tatcatgaat ctataatatt
    16381 tttttgattc ataactaaaa gtatataaaa atgatgaata aatatatatt atacattatc
    16441 aatgataggt tatataataa aatcactaac aattatatta taagaaaatt ataaaaatta
    16501 caaggaggta tagaaatgaa agaaaaagca gggattagaa atgccataat agcagccttt
    16561 ataatcacaa tattggcaga attaattgga cctatttcat ttaaagttat gggaattaat
    16621 gtaactttac ttagtatact atgggctata ttcataggaa tggctgtttc tcctcattta
    16681 ttagggagag ttataccagc cttaaaaaag tttatagggg ataatgaaat aaatgtatct
    16741 ccatatttat tatctttgac actatatcca ttagggataa tgtttggaat taatgcaggg
    16801 cctaaagttg gtatattact tcaagcagga ccagcacttt tattacaaga atttggtcat
    16861 atgggtacaa tgttgatagc attacctgtt ggagtagcat taggtcttgg aagaagtgca
    16921 ttaggtggta ctttttcatt atgtcgtgac acagcactag gaattattgg agataagtat
    16981 ggattaaact caccagaagg tataggaaca ctaggaactt acataagtgg tagtatattt
    17041 ggaacattat tattttcatt tttagcacca gtgggtgtac ttttaggatt tcatccatat
    17101 gctttagcaa tggcatcagg aatgggtagt ggttcaatga tgggagctgc aacagcatca
    17161 ttaatgaata cagttccaca aatgtcagag cagattttag catattcagc tactagtgga
    17221 ttgattacag ctgttactgg aatatatata gaattattct tatctttacc agtagccaac
    17281 tactattata gcaaagtagc tccagttatt gaaagattta gaggaagaaa aacaagaaga
    17341 acaagtaata aattgtaaag gaggatatat atatggaaaa aacttttaag actattatgg
    17401 agcagataaa aatagtattg tttatatata ttattatttg ctttggacaa atgatagcac
    17461 ttaagactca ggctcaagat ttgttgattg gaagtgtatc tggatttttg ttggtgataa
    17521 ttgctattat aataaagaat tttgttaaaa aacctaattt accaggtttt gcatgggcta
    17581 cattagttgc atttgtttta tcgcttccaa tatctccagt gggggatatc atagcaacaa
    17641 atgtagggaa aatcaatttt atgtctacag taacaccatt attagctttt gcaggaatct
    17701 ctgtaggtaa tcaattagat atattaaaga ctttgagttg gaagttagta gttatatcat
    17761 ttatagttat gacatctact tactttggtt ctgcttttat atctcaaaca gttttaagat
    17821 taaatggaat gctttaagga ggtagtaaat atgaatgaat taaaagcaaa aattaaagag
    17881 gaaataaagt tattatctga agagaaaaag acatcatttg aaaaagtttc tgactattta
    17941 ttttcaaatc cagaattagc atttgaggag tataagtcac aaaaagcatt atgtgatttg
    18001 ttagaagaaa atgaatttaa tgtaactaaa ggtgtaggag gattagaaac atcttttgaa
    18061 gctgtgtatt caaatggaac taatgggaaa acagttgctt ttttagctga atatgatgca
    18121 cttccaggaa tgggacatgc atgtgggcac aatatcatag ggacaagttc tgttggtgca
    18181 ggtatcatat taaaagaaat catgaaaaaa cataatatag aagggactgt aaaggttttt
    18241 ggaacacctg cagaagaaag agtaggtgga aaaataacta tgattaaaga aggtgtattt
    18301 aataatgtag atgctgcatt aattttacat ccaagtgatg cttcaatgcc tgatgatata
    18361 tcatttgctc aagttaattt aaaatttgat tttactggta aggcatcaca tgctgctgct
    18421 tttccttggg aagggaaaag tgccttaagt ggagtaatag cactatttaa cagtgtaaat
    18481 agcatgagat tacatcttaa agattatgca agagtacatg gaattataac tgatggaggt
    18541 agcatacata atataattcc tgaaaaatct acagctatat ttaatgtaag agccttaagt
    18601 atagaatatt taaatgagat ttgtgaaatg cttaaaaatt gtgctaaagg agctgcaatt
    18661 tctactggaa ctaatgtaga aatagttcaa ttagatgaaa tatacaaaga gattaagaat
    18721 gattctgaat tagtgaatat agttagacaa aattttgaag ttttgggtga agactatgtt
    18781 gaaagagatt taagtcaagg tataggttca actgatacag gaaatttaac tcatgagata
    18841 cctgcaatac aagcatatat aaaattaaaa gaaaatactg caactcatac agatgaattt
    18901 gctgttgcag ctggtggtga agaaggcaga gtagcactta taaaagcaat taaggtgtta
    18961 gcaatgtgtg gagtagatat tttgtatagt aaataatata taattttaaa atatattaag
    19021 aaaggaaatc ggattagaca tgatattaaa acaagtaata gaggtttatg acattttaga
    19081 taaagcaaat gctaatgggg aagaagtaaa aacttactta caaggttatg gtgaagtaga
    19141 tgtaactgta aaagaattgt cttcaagtaa aggttcaaca gatttagtaa agcttacaat
    19201 tcctggaaaa aatggaaaat taaaaggtgg agatgctcct actcttggta ttttaggtag
    19261 actaggaggg attggagcaa gaccagaagt tataggtttt gtctcagatg gtgatggagc
    19321 attggtagca attgcagtgg ctgctaaact tttggatatg caacgaaaag gggatatatt
    19381 agatggtgat gttgtaattt caactcatat ttgcccagat gctccaacta aagaacacta
    19441 tcctactcct tttatggatt ctccaattga tatgatgact atgaatgaaa atgaagttga
    19501 tagtagttgt gatgcaatac tttctataga tactactaaa ggaaatagag taatcaatac
    19561 tagaggattt gcaatatcgc caactgttaa agaaggctac atattaaaaa ctagtgataa
    19621 ccttttagat attatgcaga ctgtaacagg gaaatctcca tttgtattcc ctttgtctat
    19681 tcaagatata acaccatatg gaaataatct gtatcactta aatagtattt tacaaccagc
    19741 agtagctaca gatgcaccaa tagtaggagt agcaattaca acagagatgc ctgttgctgg
    19801 atgtgctaca ggtgcaacta attttagtga tttagattca gctgggagat ttgcaattga
    19861 agttgccaag ctatttggta gaaataagtg tgatttctat gataaagaag agtgggaaat
    19921 gcttattaag agatatggca aattaaatag atttcaaaca tttggtatac agtaattaga
    19981 aaaatattaa gtttatataa tttgtgatat aactatttaa gaatatataa acaattagga
    20041 ataaaagtaa gaataaagca cttagttaaa aactttaaaa ataaaatatt tatttgttta
    20101 tataaaaagg aggattctgg ttattgggat tctctttttt atgaatacaa ataatatatt
    20161 gtaattataa aaaaaggagc gtttcaaagt gattttttta atcaccttga gacaactcct
    20221 tatattttta tttaaattct attttttatt aagttgctgg agttccacca ccatcaggag
    20281 gagtagtaga gccaccacca ttatttccac caccatcagg aggagtagta gagccaccac
    20341 cattgtttcc gccattatca ggaggagtag tagagccacc accattattt ccgccattat
    20401 caggaggagt agtagagcca ccaccattgt ttccgccatt atcaggaggt gtagaaccgc
    20461 caccattatc acctgtgtta ttattgttat tattattttc ttctggttgg ttattgtctg
    20521 gtttttttgt atcttcagat gatggttgag aacttacttt agtaggagca gtaccttcaa
    20581 taaatgctgc tttagagcca gaagattgct ttcctccatc ctctaaatta atttttgtaa
    20641 aatatacatt tttaggaact tcaaattcag taaccgttaa attagcatgt attttttcca
    20701 taattttttc ccatagtttt gcagtactag tacttccatg tggtacttct ctacgtttta
    20761 tagtgttacc agaatcatct tttctaccag catcatctcc aatataagtt gcaccaacat
    20821 aataaggagt gtaaccgaca aaccaagcat catatgcact atttgtagta cctgttttac
    20881 ctgctacagg cattcccttt ggaagtgtag caacaccacc agtaccttca gtaattacgc
    20941 tttctaacat atctgtaaca acataagcta cttcagggtc tacaacttta tgttcttcag
    21001 gagcattttt aactaataat tgaccatcaa aggtagttat agtagtaaaa atagaaggtt
    21061 ctacataaat accgtgattt gccaatgtac cataagcagc agccatttga agtggagtaa
    21121 taccattcgc cataccacct agtgtcaatg atgggaattt tctatcactt gcttcagatg
    21181 aacctgagtg attattcttt aaagttgtta taccaaagtt ctttaagtaa tccatcatta
    21241 tatctacaca ttcatcataa gagtctccaa gcatttcagc agttttgaca gctatcgtgt
    21301 ttgaagattt agcaagtgct ttacgtaaac tcatagaacc atgaccagca gtagtagttc
    21361 ttggattcca tttattattt tcttcaaact tatatcctcc tcgagaatca cttagagcag
    21421 ttgcttgtgt tatttttaga gtatcaatag ctggcgtata tattgctaaa ggttttatag
    21481 aagaacctgg ctgatgaggg ttagtagcac gatttaaagt ttttctacca cttatatttc
    21541 ttcctccagc tagtgctctt atttcaccat ttttataatc taagattacc attgcagctt
    21601 gcggttggct aactccatca ggaccgacca tatgtcctgg gaaattgcta tttctatcaa
    21661 attcttcttc taaagcatct tgcattttag ggtctatagt tgtgtttaca attagaccac
    21721 cattgtagaa taagttttga gcttcatcat ttgtatgtcc ttgttccatt aaagcattta
    21781 taacttcact ttcgataagg tcttctacag atgaagaaac tttatctgat gattgaggca
    21841 attttatttc tattttagct ttgattgctt catcatattc actttgtttt atatatttca
    21901 attctaacat tttctttaaa acaatttctt gtcttttttt agcttcagga ttacttacag
    21961 cctttctaac aactaatgta cctgctttta attgtctata agtatcatta gatataagct
    22021 cccaagattt tattttttca atcatatcaa agtccacttg agtagggtca tctaaatcat
    22081 catcagttgt gttaacaaaa aataataatt tattctctaa atcctcctta gtttcatttc
    22141 cctctaactt agaagtttta taggctgaaa atcttgatgg atttttagtt gaaccagcaa
    22201 gaagtgctga ctctgctaga gtaaggtcag ctgcagactt atcaaaataa ccacgtgcac
    22261 cagcctcagc acctgctaga cctctaccaa cgaagaagtt atttaaataa gtttctagta
    22321 ttttatcttt acttactgtt ttactcatct catgtgcata gtaaatatcc tttattttac
    22381 gaggtatagt ttgctgttca gttgttaaca gcattttgga tacctgcata ggaatagtac
    22441 taccaccttg cttagtacct gtaagggtct ttaatactga cctaaataaa cctttaatat
    22501 cgacaccctt atgctcataa aaacgctcat cttctattgc aattacagca tgttgaagat
    22561 aaggggaaat cttatctaat ggaacgggtg tctttttatt tacacttgga gctgtagata
    22621 atgtttttcc attagcgtat ttaatagtag ttgtttggtt cgtctgttta tctaaaacag
    22681 cttctgtaac tggagttaca tctcttagtg acgcaaatac tagaccagca gtacctgctg
    22741 taccaacaac tagtaaaact aaaaatacta tcccaaatac tcttagtttt ttaaatttat
    22801 cgcttttttt agattttttc ttgttttttg ttgaacgagt cttgttagct gaagttctat
    22861 taattggttt atttgtatta ccagatgagc taactttttt tctcctgatt ttatttccat
    22921 ttttatcatt atcgttattc ataagatttt aacctcctta cttaatgcaa tattataaca
    22981 caaataggag tagttttgta attaatagaa aaaatgaatt tgctataata ttctgtacat
    23041 tgtatatgta taaacgtaat atattaaaaa gtctatattt ttattttatt tatttttgac
    23101 aaatattata aaaattatgc caaagctaca tataaataaa taggagggga taattttgaa
    23161 tagaatagta gatagaaaaa caaaaaatga atttagaaaa atcatagcta tttttttagt
    23221 aattcttttc ttgtctgtat ttataggcag ttttatatat atagataaaa ctttaagacc
    23281 gacaataaca gttttagcag agactaaagc tcttgaacta gcaaataggt cgataaataa
    23341 agctgttgct gagatggtag aaggaaaaat aaattatgaa gatttaatgg atatacaact
    23401 tgataataat ggtaaaataa ctatgataca agcaaacact ataatgatga atgaaattgc
    23461 atctgcaata gctttagaaa tacaagatga attaaaaaag gataagacag caagttctta
    23521 catacctata ggaacagcat taggaagtcc tatattagct aaatacggtc ctaaacttga
    23581 agtatctatt gaacctatag gaacagtatc agtaaacttt aaaacggaat ttgagtcttc
    23641 aggtataaat caaactagac atagaatata tttagaagct caaacacaag ttaaagtagt
    23701 aataccactt ataacttcaa caaaacaaat taaagctcaa atacctattt gtgaaactat
    23761 aatagtaggt gatgttccag aaagttatgt aaatattcca gaaaaaaatc taggaaatgt
    23821 tttacctaac actggaaaga ataccaacaa gtaatgtaaa gttgtatatt tttaaataaa
    23881 ttcaaaataa tagtttataa ataaaatttt tggaaataat attaatataa ttttaataaa
    23941 aatttatatt ttatactatg taaaatatct aatatatttg gtctgtaggt taaataaaag
    24001 tacctttaga ccaaatatat tattaataac ttaataacat cttaaaactt atttatttat
    24061 attatttaca acatccattt aataaataca ccataaccta cagctgggtc gttttcaatt
    24121 gcatgtgaca ctgctccgat tattttatta tcttgaacta ttggagtacc actcatacct
    24181 tgtacaatac caccagtttg agctaaaagc tttttatctg taattttaat tttaaaactt
    24241 ttactttctg gatgtttttg gttttctata tctataattt caatattata ttttttacac
    24301 ttattaaagt tatcttgtaa aattatttga gcttttccta atttaacttc atctaaagat
    24361 gctactttat atttttttaa cttggaaata tcaaagttat taatttgacc tcttattcca
    24421 aaatcagtat tttctgtaaa gctaccaata atattttctc gttttgcatt tatacatcca
    24481 acactacctt tataagattt ttctatatta aggtgcttag ttgtagaaat tgaacctgtt
    24541 ttaataggta tttttcttgc attaccaaca cttattggat gacctacagc tccaaactct
    24601 gatgtatctg gattgatata cgttaaagta gcaaatccag aaagtaaatt gttaaaacta
    24661 attttttcta atatgtgttt ggtagttttc attgttataa gttgtccacc tctatttaat
    24721 aaaatagata cttgtttttc ttctggtaaa gcatttaagg tattggcaaa gtcactatat
    24781 ccatcaactt cagcattatt tacctttact atagcatcac ccaatctaaa tggagatgct
    24841 tctccaggat ttctaactat gatatttttt aattctgcgt caatttgaag tacgtttcca
    24901 attggtatta aatattcagg ttcatttttt tgtaaatttt gtgcataaat taaattattt
    24961 gagaaaaaat ataataaaaa taaaaatgtt aaaacaattg taaattttga cttagctaag
    25021 ttggtttttt tacttaaagt attattttta aaatgaaaat ttttaagttg cataaaacac
    25081 ctctttctta ttaaattatt ttaataatag aattgaagtt ttcttgctgc ttctatatta
    25141 tgttgtgcaa gaatcatgtt ttgatgcttg gaaaactagc tcaataacac cttagttttc
    25201 ataaaaataa ataaaataaa tagtgtatat gataaaataa atacatattc atataaataa
    25261 aaataaacaa taactgtcta gcataagaaa ggagcaaaaa atgaaaaaat atagattgtt
    25321 agttacttgt ataattgcca tgggaatcat aattatagga acatcaaatc cagttagcaa
    25381 tttttacaag actacaaatt tgattagttc aggaaatatc acaaatgaaa aagcagataa
    25441 agatgaaaat tcaaacaaaa ataataaaga taaaaatgaa gacaaatcta attctaaaag
    25501 taataaagat aagtcatcag aggacaaatc gtcagataat aaaaatgaaa ttcaaaaaaa
    25561 taaaaaactt ttaatttgta tagacccagg gcatcaagga aaaggagata gcaatttaga
    25621 accagtagct ccaggttctt cctctaaaaa agcgagagta tcttcaggaa cagagggtat
    25681 tgctacaaaa aagccagaat atgttttaaa cttagaagca tctcttgttt taaagagtat
    25741 attagaatct aaaggttata atgtaataat gactagagag acacatgatg taaatataag
    25801 taattcagaa agagcaatac ttgctaatga caaaaaagca gatatggttg taagaataca
    25861 tgcagatagt ttaaataatt cttcaaaaac tggagcatct atattgattc ctgaaaaaga
    25921 tggaaaatat acagctccta tatatgaaga aagtaataaa tgtgctgaat ttatcaaaca
    25981 gaatatggaa caatcaggta tacaaatcaa tggaatcgtt caaagaggtg atttgactgg
    26041 attcaactgg tcaaaagtac cagctgtatt agtagaaatg ggatttatga gtaactataa
    26101 tgaagaccaa atgatgtcaa atccagacta ccaaagaaaa atgatgcagt gtatagctga
    26161 tggattggat gcgtatttta aataagatat gaatagagaa aaagttaggt tggtattatt
    26221 tgcctaattt ttatctctat tttttattgt acataacaca aagaagaagt ttattttagg
    26281 ttaaattgtc gtaaatataa ctaaaaatat tgggaatact tgatttaagt ttaaaaagaa
    26341 tatattatag tatagaatgt gtaaaatttt tttgagaggt gttgaaatgc tagtagtaga
    26401 aaatgtgagt catggatttg gtgcgagaac aatattagaa aatgtatcct ttagacttag
    26461 aaaaggtgaa catattgcac tagttggtgc taatggagaa ggaaaatcga gttttttaaa
    26521 tataataaca aagaagctta tgccagatgc tggaaatata aaatggtctt caagagctac
    26581 agtaggttac ttagaccaac atacggtatt aagcaaggga aaaactataa gagaagtgct
    26641 tagagaggct tttaagcata tgtttgactt agagcaagaa atgattgcta tgtatgacaa
    26701 aatgggagaa gctagtgatg atgaaatgag taagcttctt gaagaaacag cagagataca
    26761 aactatactt gaaaatagtg gtttttatat gatagatgca aagatacaag aagttgcaaa
    26821 tggtcttggt cttggagaaa ttggtcttga taaagatgta actgacttaa gtggagggca
    26881 aagaacaaaa gtacttctta ctaaacttct acttgaaaat ccaactattc ttatattgga
    26941 tgagcctaca aactatttag acgaagagca tataacatgg cttactaagt accttcaaga
    27001 gtatgagaat agttttgtct tagtttctca tgatattgaa tttataaata atacatgtaa
    27061 tgtaatatat catatggaaa atggagagtt aaatagatat aaaggaaatt atgatgaatt
    27121 tgtaagactt aatgatataa agaaacgtca agaagaacaa gcttatgata aacaagttga
    27181 agaaagaaaa agactagagg attttgtagc tagaaataaa gctagagtag caactagagg
    27241 aatggctaac agtaggcaaa agcaacttga taagatggaa atattagaaa gaccaaaaga
    27301 aaaaataaaa cctacttttg cttttaaaga tgctagagca gctagtaaaa taatttttga
    27361 aacagaaaat ttagttttag ggtatgatga agcattgaca aaaccactta atttccattt
    27421 agaaagagga aaaaagattg ccttaaaagg aatgaatggt attggaaaat ctaccctatt
    27481 aaaaacttta cttggaataa taaaaccatt tgaaggaaat gttaaattag gtgactattt
    27541 ggaagttgga tattttgaac aagagagttc aagagaaaat agtaatacac ctatggatga
    27601 agtttggagt gaatttccag ggcttacaaa ctttgaagtt agacaggctc ttgcaaaatg
    27661 tggacttaca aatgaacata taacgagtca aatgagagta ttaagtggtg gagaagctgc
    27721 taaggttaga ctttgcaaag taatgttaaa aaatataaat ttcttagtat tagatgagcc
    27781 tacaaatcat ttagatgttg aggcaaaaga tgaattgaag aaggctatca aagagtttaa
    27841 gggaacagtt cttttagtat gtcatgagcc agaattttat tcagaaattg ttgatgatgt
    27901 atggaatata gaagatttta caactaaaat cgtgtagtga tttaacttat tgctgggggg
    27961 atttcatgaa aaagtttcta aatgtacttt tttcaatttg tattagtatt gttataatag
    28021 taggtgttat taattttact gttggattta aacaacttta ttattttgac attgattact
    28081 taaatatatc agagttatct ggtttatcta aagatgatat aaaattgaac tacgattatc
    28141 taattgatta taacttaaat aagaatgtgt ctgagttcaa attaccaaca ttaaaatctt
    28201 ctccacaagg gaagatacat tttgaagaag tcaggaatat atttcaaaat ataaataaat
    28261 tagctaaatt attattggta gtttctttag taggaattat attgagtgta aaaaataaaa
    28321 atataaaaat cttaaaaact acatcaataa cacttataat tatgccatta ttattaacag
    28381 ttccaatttt attaaatttt gaaaagtcat ttattatttt tcataaatta ttatttagaa
    28441 atgattattg gatatttaat cccgatttag acccagttat aaatatattg ccagaggaat
    28501 ttttttttca ctctggaatg atgattttaa tattaatttt gttagtaagt atagtactgt
    28561 ttgtaatgta taaattatgt aaatctttat caataaaaat atttcaatgt taaatagagg
    28621 gatattttta tttccaaaat aagataataa aaaaggatta gattaaaagt tatacaataa
    28681 aaatagctgt gcaataatat ttagactatg aaagtagttg aaaaatattt atgcacagct
    28741 atttataata gaatttactt tttactagtg attttaacta aatcttgaaa tttactcata
    28801 atgtaattgt aattatcttt tttatgaggt aatatacaac tactgcaatc tttgatacct
    28861 ttatctgtat acctaaagtt tccaccacag ttttctccta aagcatacaa aggacaatag
    28921 caaaatagac agttaaactc ttctggttta ttagttttat gacaagggaa aaattcgcaa
    28981 tctttgtgat taaaaaactt ataattttcg cccatatttt cctcctaatt aaataaaatt
    29041 taaatttttt atactatata agattttggt gataatataa ttatactaaa taattttatg
    29101 aatagtcgat aatatagtat tattaatcat agtattaatg gtataattag tcaacagaaa
    29161 aataatgtaa aaataatgta agtgtatttt gtaattagaa tatgttttat aacaaaaaat
    29221 gaggtgatta agtgaaagaa attcaagaaa aagcacttct tgtaggtctg aatttgacta
    29281 caatagtgaa aaaaaatgat gatatagaca ctaatgaatc tatggaagaa ttaaaagaac
    29341 taacaaaagc tgctggggca gaagttgtag gtagcttaat tcaaaataaa cactctgtag
    29401 atgcagctta ttatatagga aaaggtaaag tagaagaaat aagagcctat agtgactctt
    29461 tagatgctac tttagtaatt tttaatgatg aattatctgg tgctcaaatc agaaatatag
    29521 agaatgttgt tggaagaaaa gtaatagata gaactacttt aattttagat atatttgctc
    29581 aaagggcact tagcaaagaa ggtaaattac aagttgaatt agcacaatta aaatatagat
    29641 tgccacgact ttatggaatg ggtggtgaga tgagtagaac aggtgcaggg attggtacta
    29701 gaggtcctgg agaacaaaaa ctagaaatag ataagagaca tatacttaat aaagcagcag
    29761 atataagacg tgaacttaaa gaagtaaaaa agaatagaga gacacagaga gttaagcgtt
    29821 taaagtcaaa tataccgatt gtagcacttg ttgggtatac aaatgcagga aaatctaccc
    29881 tgttgaacga attaataaag acacacaagg attatgaaca agaaaaagaa gtttttgtaa
    29941 aagatatgct ttttgcaact ttagatgtaa ctttgagaaa ggctcttttg ccgaataaaa
    30001 aagaattttt agtagtagat actgttggat ttgtaagtaa acttccccat gatttagtag
    30061 aagcgtttaa ggcaacattg gaagaagtac agtatgcaaa tttaatctta catgtaattg
    30121 atgcaacaaa tactagttat gaattgcaaa aaagtacgac tgaaggtgta ttaaaagaac
    30181 ttggtgtaaa tgataaaaaa catatacttg tatataataa agtggacaag ctagaattgg
    30241 atatataccc taaaagtcaa gaagatattg tgtatatttc tgcaaaacaa ggcataaata
    30301 tggataagtt attaaatatg atagaaattg ctttaatgga aaatacttat tcagtaagtt
    30361 tgatgttacc ttatgagaga ggtgatatat ttagtagaat aaaagataaa tataatgtgg
    30421 agaattttga gtatggggaa agtggtataa cgctagatgc agatttagat gaagaagatt
    30481 ttaatatcta tagagagtac atactagaaa aataggttga atatggatat aaactgggaa
    30541 aatatagata atcttgaaga ttattttata acctatcttc tttataaaga atctaaaaca
    30601 gtatctcaaa ttagtaaaat tagaaatatt tcaagtactg aagcaagtga gcaacttata
    30661 caagcaaagt taaaaataaa ggaaatgcaa aaagatgatt ttgaggcatc taaggatatt
    30721 ttggataaat ttctagaact agataaaatt aagagacttg attttatgga tagcttagat
    30781 gacgaaaaaa tggtatactt taagagaaag gttttcaaaa gaatccttgt agaaaaaaat
    30841 gctgaagatt taattgtttt aatttgggcg acaggtgagc taaaagatga taggtttttg
    30901 aaattgcttc atcagctcac aaaccacaga cactcagata ttagaagaat aacttattca
    30961 gcaatcagaa agattgaatc accaagtagt agagaagtac tgcaaaaagg tctctacgac
    31021 aaaaatgcac agactaggca gtactgtgca aaagctcttt caaaattggg agatgaaaac
    31081 agtttaaaga ttttacagca gttgaaagac aagaataaga attttgaaaa agaatatgtg
    31141 cttagagctt atgacgaagc cattaagtca ttggaaaatg caaaaaattt gaaaaagtaa
    31201 ttttttatta aagcaatttg tttacttaat gatgtatttc taaagtttaa caaggtaata
    31261 aataaattaa tgggaggggt ttcaaatgat agtaagacgt tgtgcaggtg gagtagtgtt
    31321 ttatgctaat aaagtactta ttgtaaaaaa tgataggggt gaatggacac ttccaaaagg
    31381 aaagatacta ggagggggac ttccatatga gagtgctgtt caaagagtta aagtagaaac
    31441 tggcatagat gctaaaatga tagatgtggc tggcgatact atgtatgaat ttttctcaag
    31501 aagtagacaa caagaagttt gtaatgcaat aatgtggtat gttatggaag cttgtaacac
    31561 tgattgtgta cttgctcctg aatttcaaga aggtggattt tataaagtaa aggatgcttt
    31621 agaaatgtta tcacatcata aagagcaagc tttagtagaa gtatcttata aaaagtttaa
    31681 ggaattaaag aaattagttt cagagggcga tgatgttcca gcaaattaat tgtgaattta
    31741 gaggattctg aggaagggat agccccttcc ttttttaatt gaagcagttt taagcgtaaa
    31801 ttatatagtc tctttaaact atgatttatc aatttagaga tttagtagtt tatatttaaa
    31861 atcagtaaga tatatttaaa ataaaaatta aaaagtatac aattttatta tataattgtc
    31921 ttatgatgtt gattaaagaa gtattaaaag tccatttatt tttaaataga atgattttat
    31981 aaatatatat ttgatgtgta tattagaaaa tgattaaaat aggaggaaat acaatgagca
    32041 attacaggac attacatgaa tttggaacgg atgaaataac gattgaaaag tctgttttta
    32101 ttggatatgc taagcctata aagagtgaag aagaagcatt agagtttata aatgaaataa
    32161 agaaaaagca taaagatgca actcataatg tgtgggctta tactgtaggt aaaaatatga
    32221 atatacaaag atatagtgat gatggagaac cacaaggaac agctgggata cctacattag
    32281 aggttataaa aaaagaagat ttgagagatg tagcggttgt tgttactagg tattttggag
    32341 gaacaaaatt aggtgcaggt ggtctagtta gagcttatac aaaaggtgct aaactgggac
    32401 ttgaagcagg taagataatt tataaggtaa tgtatcaaga agttaaggtt aagatagatt
    32461 atactcaact tggaaaagtg caaaatgagt taatgaattt ggggtatttt ataaaagata
    32521 ctgtatatga ggataatgtt gaaatagtag tatattcaag attagaagat gtagagaaat
    32581 tatcagaaaa aatgattgat ataacaagtg gaacaggaaa aatagtttta ggagaggaat
    32641 tttatttgtc tgaacaaaat ggagaaattt taatataatc taaaaggtta ttagaatagt
    32701 taatacctca aatagccaat tagtattttt aagtgaaaag ccattaaatt gatttaatct
    32761 aaatcaattt aatggctttt tatcggattt tgcacagaat ccttttttta cttcaaataa
    32821 accgactaaa agtaaaaata tcccaaatat tttttttaat atatctgaag acagataatt
    32881 agctaatagt gaaccaaata cagctcctaa aaccccaaac acagctatag gtataaccaa
    32941 tttaaaaatt acatttttat tttttatatg tatagcaagt gctataagtg tcatagggat
    33001 agatgaaagt aaatttacgc tttgtgctat tttagtgtct atgccagcaa gtaaaacgag
    33061 tgcaggtata aggattgttc ctccacccat tcccattcct ccaataattc ctgcaaaaaa
    33121 tccaattaga gcaaataaca ttaaaacacc atccttaatg ctgcaattat cataattatt
    33181 ccaaaagaaa ttctaagaaa ctttccagta accttattta gtaatttagc tcctataata
    33241 ccaccaagaa tacttccaac tgcaacttta attgttaagt taacatcata agtaccttta
    33301 gatacatata aaacagaact tgctgtcgtt aagaatatta ttatagaaag agcagttgca
    33361 tgagatttat gttcttctac cttaacgatg tcatttaata ttggaactaa aagagtacct
    33421 cctccagaac caaaaactcc atttataaat cctgtaaaaa ctccaattat cgtatttttt
    33481 aaattaaaat caaagtattt tttctttaaa tcatcagttt ttttcataaa aatcaccttc
    33541 tgaaatagtt ttaccaaaat aggcaaatta tatttatata aaataagatt aaatataatc
    33601 tttcatgttt gtttaatttt gcataaaaaa aaacatatta aaacaacata ttaatatatg
    33661 gtataatata ttaaaacaaa gtagcaaatt tgagaggaga taacaatgtc aaatataaaa
    33721 atacaaatag acaaaactgt agaatggctt ataaataagg ttaatgaggc aaatgcaaaa
    33781 ggattaattg ttggtgtatc tggaggaatt gattcggcag tagttgctaa tttaattaaa
    33841 aaggcatttc cagaaaactc tatgggagtt ataatgagca taaaaagtaa tcctcaagat
    33901 agagaagatg cacttaaggt tatagaggga tgtgatatag aataccttga tttagacctt
    33961 atagaaccac aaagtgctat attagacatg gtagtaggaa atttaaaaga taaacattta
    34021 tatagagaag aatatttaaa gatgacagat gcaaacttaa gagcaagagt aagaatgagt
    34081 acaatttata caattgctaa caatctagga tatctggttg ttggtacaga caatgctgca
    34141 gaaatacaca caggatattt tactaaattt ggtgatggtg gagttgatat tttacctatt
    34201 gcaaatttaa ctaaaggaga ggtgtatgaa tgggcaaaag agcttggtgt tcatgaagat
    34261 ttaataaaca aagctccttc agcaggtctt tgggaaggtc aaacagatga agatgaaatg
    34321 ggaactactt acaatatgat agatgctgta ttagaaggta gattggatga agttcctaaa
    34381 agagaccaag agataattga aagacttcat agattaagtg aacacaagag aaaaacgcct
    34441 gcacaacctc ctaagttcta atttactatt tataagattt gtgataaaat ttacaagtga
    34501 tgaaaattag aataattaat tgtacgtatt aaggagtgga aatatgggac gtataggtaa
    34561 tataattaat agaaaaggta aacaagatgc tcaaagagca aagatattta ctaaacatgc
    34621 tagagcaata gcagttgcag ctaaggaagg tggagcagac ccagagtaca atgcagcgtt
    34681 aaaaacagct atagaaaaag ctaaggcaga taatatgcca aatgataata tagatagagc
    34741 tatcgctaaa ggtgctggag caggtgctgg agaagactat gaaactatag tttatgaagg
    34801 atatggacct ggtggagttg ctgttatagt agaaacttta actgacaaca aaaacagaac
    34861 tgctggtaac gtaagatact attttgacaa aaacggagga aacttaggaa ctagtggatg
    34921 tgtgtctttc atgtttgata aaaaaggaca aatattagtt ggtttaggag atggagtttc
    34981 agaagaagaa ttgatggatg ttgcattaga agcaggagct gaagatttca taacagaaga
    35041 agatggttat gaaataataa ctacaccaga agatttttct agtgttcgtg atgagttaaa
    35101 agctaaagga tatgagttta tatctgctga tgtgaagatg atacctcaaa ctacaactgt
    35161 attgactgaa gaatctcatt taaaaatgat gaataaatta gttgatatgc ttgaagaaga
    35221 tgatgatgtt caagatatat atcataactg ggaagtagaa taaatagtat aagcatattg
    35281 aaatttataa gtattgaatc aattttaaca tgtgataaat tttatagaat aagaaacact
    35341 aaaatagaca tacgcacctc taacctatat ttgcataata atatgtaagc ataggtaagg
    35401 ggtgttttta tatttatagg ttaagaaatt taaagtaaat tttgagctgg actcgattgt
    35461 ctataaataa ttgatgggta tataacttgt tgctgaatac catttatacg cccagttact
    35521 gtatcaataa tcatcctaag actacgttct gctgtctctt ccatttttaa atctataact
    35581 gtcaaaggag gaatacttct tgccattagt cgtgaaggtc cattacttgc tgcaaatatt
    35641 tgaatatcct ctccaattac aattcccgat tcatgaaatg cattcatcat accaagagct
    35701 accacatcat gattacaaaa aattactttt tttagtgaat tttttgcaag cattttttga
    35761 gcaatatcat atccactatc tattttatta gaacaataat atatagaatc tgatagatgt
    35821 attccatgtt ctttacatgt ttttaaaaaa gatttacccc ttaaagtcat acatgtaaag
    35881 gaagttgggt tgaatacaac agcaatatca tttttaccat tttgaatagc atgtaaagct
    35941 gctatacgac cagtttcctc attatcaata gatacacttg aaaaaccagg tatttcacga
    36001 tttacaacaa ctacaggaat tttaggttta ttttttacta gatattctat atcatcagca
    36061 ttgatacctg ttaaaacaat tccatcataa taattatttg caaaaaagta ttcatcatca
    36121 catagatgac caactttgta aggtcgtatg atgatattta tgtttaaatg ttctaaagaa
    36181 attatgtggt ttattgcttg aagtatattg gttgatgcca actcaaatcc ctcatcctgc
    36241 caataaaaag ctattttaat attattatgt ttaataggag tagagcgttt atatccaagc
    36301 ttatcagctg aatttaatat aagctcttgt gtatgtagcg gaatcctgcg ttcatttcct
    36361 ttaccactta agacgtacga gacagttgct gaagaaagac cacagtcttt tgcaatatct
    36421 ttgattgttg ccatgataaa atcctcctta aatagttgct taaatttgct tataccaata
    36481 atcttaacat atattcaact aaagaacaat attctacaag gtgcatattt tacaggatta
    36541 gaataaataa attaaaaaaa acttcttact tatgttgaca taatttagtt tataggatta
    36601 taatatgctt aaataagctt atgattaact tgaattaagc aaagttaagc aggaacatgc
    36661 aatgctagct tgcaatgtga ctgcaaaggg ggaaaaggta tgagtaaggt aaatatattt
    36721 gaagttggtc ctagagatgg atttcaaaac ctgaaagagt ttttagaaac tgataaaaag
    36781 cttaagatta ttgatggtct tattgcttct gggattaaac aacttgaaat tagttcattt
    36841 gtaagcccaa aagcaatacc tcagatgaaa gatgcaaaag aagtagcaac ttattgtgta
    36901 gaaaaatatc ctgatgtgaa actttatgca ttagttccaa atttatatgg tgctaaagtt
    36961 gcatgggagt gtggtataag agatatatcc tatgttatat ctttgagtga aactcataat
    37021 aaaaaaaata taaatcgtac ccatgaagag tctattgatg agcttaaaaa aataatgaat
    37081 acttatccag acatgaatat atgtattgga atggctactg tatttggatg tccttttgaa
    37141 ggtttaccaa aaattgaaga tgccataaga tttgctaaac gcctttggga aaacggtatc
    37201 agggagataa atctagcaga tacaataggg attgctgacc ctaagcaagt aagagaaact
    37261 attagtgcat tagttgaagc tttaccagaa tgcagatggc aagtacatat tcatgatact
    37321 agaaatatgg gaatggttaa tactcttgtg gctattgaat ctggaattac tactgttcag
    37381 tctacacttg gaggattagg aggatgccca tttgctcctg gagcatctgg caatactgca
    37441 actgaagatt tagtatatat gcttgaacgt atggggtatg atacaggagt tgattttgtt
    37501 aaacttcttg aattatcaaa atatcagaag agttttgtaa atggagtata tagtggtcat
    37561 catgtaaata taaagtctga tagttgtaat tgttagttct attgattaat cgattaaaaa
    37621 aatatgctga ttggtaaaat agatttattg ataaaaaata taaattataa aatacattat
    37681 ctaataaaac aaataaaaaa attgaggggg attagtatgg atattatagc tttactttta
    37741 tttttaggag ttattattat tgcatttgta cgtaagaata atgcaggtat tttggctcta
    37801 gctattggtg tcatagctgt tagaattttt ggaatggatg ataaagaact ttatggagct
    37861 ataagcaact caatgtttac tacacttgtt ggtataacac tactctttgc aatagtgaac
    37921 tcaacaggag cattaaagct tgttgcagaa aaaattgtag ctgcttctgg taaacgtgtt
    37981 tggcttatac ctatagcagt ttttatagca ggatttgttg ttgctggtgt tggacctggg
    38041 gcaattccag cacttgcaat tatcccagca atggctgttc ctgtagccat aacagttggt
    38101 tataatcctg taatgcttgc acttataggt gaatgtggat taatggcagg tcgtatgact
    38161 cctattactc cagaaggtca aattataaca accgttgcag aaggggttgg aattgaaaat
    38221 gttatgccta ctatcttagc ctgtcaaact ctttctacaa ttgtattttc aatagtattg
    38281 tttataattt tcaaaggata taaacttaaa aaacctataa atgttataga tagtaagcaa
    38341 atagaaaaat tcaatataaa gcagataatt tctctaataa gcatagtagt tatgattgct
    38401 tttatcataa tttttgatat gaatgttggg cttgcagctt ttgcagtttc agctgtactt
    38461 atttttttca atattgctga tgaaggagaa tgtatcaaat caattccatg gagcacgata
    38521 gtaatggttc ttggagtagg tgcaatgatg acaatcgtag atgcagcagg aggtattgac
    38581 ttgatgagta atgcattatc atcactgatg aatagtaaaa cagctactcc aattatgagt
    38641 atttcagcag gacttatgtc tatggttagt tctgctttag cagtagttta tccaactatg
    38701 atgcctatgt gtgttgacat agctaaggca gttggaggag tagacccact agcacttatt
    38761 gctgcagttg gtgttggagg ttctcttgct ggtgtaagcc cactttctac tggtggggca
    38821 ttgattttag cagctatggg ttcaagtaag aaagacttta ataaggaaga acaaaataag
    38881 gtttttgtac agcttttcat tatgagtgca gttggcttat tggttattgc agtagtatca
    38941 atattatcat ttaatgcaat aacacattta atgaactaat tagaataact gaaaataaat
    39001 cattaaattt aacttttaat attaatcaat ataatataat ttggagggga agttatgaaa
    39061 aaaggagcat taagcaatat aaaggtactt gaccttacaa gagttcttgc aggtccatat
    39121 tgtacaatga tgttggcgga ttttggagct gatgttataa aaatagagat gccaagaaaa
    39181 ggtgatgata caagaggttt tggacctttt gtaaatggag agagtttata ctatgcaaat
    39241 ataaatagaa ataaaaaagg tatcactcta aaccttaaat cagaagaagg aaaaaatata
    39301 tttttagaaa tggtaaaaca tgctgatgtt gtagtagaaa attacagacc aggtgtaatg
    39361 gaaaagttag gtctgggtta tgatgagttg gctaaagtta acaatcaaat aatttatgga
    39421 gctgtatcag gatttggatg ttatggacca tattcagaac gtccaggtta tgatattatt
    39481 gcacaggcaa tgggtggtct tatgagtata acagggcaag aaggaggaga accaacgaga
    39541 gttggtaatg ctatgggtga tgtactaggt ggaatgaatt taactattgg tatactcaca
    39601 gcactcaacg ctagaaaaat aataggaaaa ggacaaagag tagatgtttc cctcgttgat
    39661 tctgttgtat cgtctctcga aactggtata cagagatact ttgattcagg acaacctgaa
    39721 cttatgggta atagatatgc ttcagcctat ccttatgact cttttaaggc aagtgatgga
    39781 agttttgtaa taggctgtgg taatgacaaa ctttttgaaa agttatgtaa aaaagttctt
    39841 tttagagaag accttttaat agatgagaga tttaaaacaa atcttaatcg ttgtgaacat
    39901 tacaaggctc ttaaaccaga aatagaaaaa tggtctgtta agcatacaat aaaagaagca
    39961 gttgacttaa tatcagaggc tggagttcct gctgctccta tctataatct tgattgtgtt
    40021 acaacagatg aacatatagc aaaagcaaga gaaatgattg tagatattag tcatcctatt
    40081 ataggaaata tgaaagtcaa tggaaatcca gttaagttga tgacaacaaa agctaaaatt
    40141 gatatgccag caccatctct aggggaaagt aacgaggaga tttataatgg ttggcttggt
    40201 tttgatagtg ataaaataaa agatttaaaa gaaaatggag ttatttgatt aaaaaatagc
    40261 taaacacact tgtgacttta gtcatgggag gttcagttag aataatatca aaaaatatta
    40321 aatcaatact gtaaataaaa tatagaattg tcagaagcat ttaagatggg aaaagctact
    40381 tagacattga gtctttgtgg cttttcctat tttcattaag aattttatat tatcagaata
    40441 gatatgtact aaactaaagt attaacaatt taaattaata gaaaataaac tacctaatta
    40501 tgttgaataa agactacttt agtgaaaata aacttataga gatgctattt aaattatttt
    40561 aatggaaata tcaaaaatga gactgcattc tcaaaaatga gactgcgttt tttaagtatt
    40621 ttctcgaaaa tgagacaaaa atattgtttt atgggtttta ttgaagaaaa attcttctgt
    40681 gaattacaat ttaatcaatt ttaaagttga aaattattaa aaatttagtg aaatttatgt
    40741 atatttcgtt tattttatta aaaataacaa ttttttacta aaaataaaga acttcaatgg
    40801 tgattggcat agtacttgct attttatatt aacaagaaat gtagaaaaaa taacaatgta
    40861 taatgggggg aatatgatgg aatctgtaat ggaaaatttg aacaatctta aggtggaggt
    40921 taaggacaaa gtctgtgtta ttactataaa tagacctaaa gctttaaatg ctcttaatag
    40981 tgacactctt agggaactat cacaagttat tgatgtagta tcagaaaatg aggcaatatt
    41041 aggagttatt attactggag aaggtaaagt ttttgtagcc ggtgctgata tacgccagat
    41101 gcaaaactat aaaagtgagg aaggcagaaa atatgcaggt tatgctcagg gaatttttga
    41161 taaaattgaa gctcttgaga aaacagtaat agcagcagtt aatggatatg cattaggtgg
    41221 tggatgtgaa cttgctatga gttgtgatat tagaattgca tcagaaaagg ctatatttgg
    41281 acaacctgaa gttaatttag gagttattcc atgttttggt ggaactcaaa gattatcaag
    41341 acttgttgga actggaatag ctaaagagtt aatttttacg gggagacaag taaatgcaga
    41401 agaagctaaa tctattggac ttattaataa agtggttcca agtgatttac ttttagaaga
    41461 gtctatgaag atgatgaacc aaatagttga aaaagcgcca atagcaataa gatatgcaaa
    41521 agttgttatt aacaaaggga tagatatgga tttaaagaat gctcttgaac tagagaaaga
    41581 tgttgcaggt ttaacttttg ctacaagaga taagcaagaa ggaatgaatg catttataga
    41641 aaagagaaag ccagtttttg aaaataaata gctattataa ctaaaattgg aacaatgtag
    41701 aatatattca aaatctaaat ttcgtgaaaa aatacatata gtttaatttt aaaaggagtt
    41761 aatttatgaa tacgggagta attataagtt tagtagggat tatcatagct ctatctcttc
    41821 tagttgtaat ggttatgaag ggaataaata tttttattat agcaattgta tgttcatcat
    41881 tagttgctat aacaggaagc ctaaatgtgt atgatgcact taaagtggat tatatgacag
    41941 ggtttgttgg atttcttcag gcaaatttct ttattttcct aacagggaca ttaatgggaa
    42001 aaataatgga gattactggt ggagcaaaat ctattgctaa gatgattgta agatggattg
    42061 ggaaggataa agcactactt tctattccaa tagcttgtgg aatattagcc tatggtggag
    42121 taagtgtttt cgttgtaagt tttgcagtgt ttccgatagc tttagaaatt tttaaagaag
    42181 ctgatttgcc acgaagattt ataccagcag ctttgacttt tggatgctca acttttgcta
    42241 tggttgcacc aggggcacca caaattcaga atattgttcc agcatcaaca ttagggacag
    42301 atattatggc tggagcagta aatggtttta tatcatgtgc agtaatgttt atagttggaa
    42361 gtacaatttt gtacaaaatg gtttcaaaag aaaaagccaa tggtggtcat tttatagcac
    42421 atgaatcaga tatatttgat gaagcagaag caactaattc taagagagaa aatggtccca
    42481 atggtgtaat tgccttaatt ccattgatag tgtcgatttt aataattaat gtaaaagtta
    42541 atggaaaagc gatagtacca attgaggtgg gagtatttat tggagcttta ttagtatatt
    42601 tattgttaaa taaatatcaa gataatacta aaatagttgg acatgttggt gatgcatgta
    42661 aaactacagt agtagcaata tgtaatactt gtgctgtagt tgcatttggt tcagtagtaa
    42721 aatcagcagt tggttttgac ttcatagtta atgctatgac taatattcct ggtcctccta
    42781 ttgcaggggc tgcagttgga actacagtta ttgcaggtat ttgtgggtca gcttcaggtg
    42841 gactaggaat tgcagctcca cttcttggac cagtattttt agccaagggt gtttccgctg
    42901 cagcattaac taggactatg gcaatttcat cagcagcatt agattcactt ccacacaatg
    42961 gatatattgt tactgtaaca aatggtcttt gtaaagaaac acataaggat gcctatatgc
    43021 caatattctg ggtaactgtt ttaaccccat ttattggaac catagtagca gtcctactgt
    43081 ttacaatgtt cccgggattg ccataggaga aaagataaaa ggtataaatt atattttgat
    43141 attataaaat caattttcaa aatatataca ataaatttca tgttttaata ctgtaaatat
    43201 gtatttaaaa taacaaattg accatataag gaggaattga aagtgttaaa taaaccatta
    43261 gagggagtta aggttattga cctaacgtat tttgtagcag gtccagggac ttctaaaata
    43321 ttagctgact ggggtgctga cgttattaag gtagagccaa gctttggaga cccaggaaga
    43381 aagacagggg caacaatgac aatgccaata gatgattata ataatccttt ttacagcaca
    43441 tataattcaa ataaaagagg tttgtctata aatcttaaga gtgaaactgg aattgaaatt
    43501 atggataagc ttttaagcga agcaaacgta tttgtttcaa gttatagaac aggagcatta
    43561 aaaagactag gtcttgatta tgaatcatta agtaaaaagc atccacacct tatctggggt
    43621 cagataaatg gttttggcga ttttggacct gctaaggata atgcaggatt tgatacagtt
    43681 gccttttggg caagaagtgg ggctatgctt gatatagcag aaaaagatac aagtccaata
    43741 aatccaccta tagcctttgg agatgcaaca acttcttgta gtttatctgg aggaatatgt
    43801 gcagctttgt accagcaagc taagactgga aaaggacaaa aagtaatggc atctttattt
    43861 gggcaagcaa tatggaatgc atcatcttta ttagcatcta cacagtttag tgatgagtat
    43921 ccaaaaacta gaaaaaatgc tatttcacca gtaataaatt cttatcgttg taaggatgga
    43981 aagtggatat tcttaagtat tttagagcat gaaagatatt ttgaggcact ttgtagatta
    44041 tttggaagag aagacttaat aaaagaagag aaatttgcat cttcagtaga aagtaagaaa
    44101 aatgctacag aacttattaa tattttagat ggtgaatttg caaagtttac tcaaaatgag
    44161 atggttgaaa aacttactgc tgctgatata gctcatgaaa aaattcaaca tgttaatgat
    44221 gtagtgactg atgaacaggc tattgctaat aactatatat atgaacatac aagtaaagat
    44281 ggaaataaga caatgcttgc atctactcca gttaaatttg gaaatattga agttaacatg
    44341 acttgtgatg ctccacttat aggagaacat tcagatgaga tattgagaga acttggatac
    44401 agtgattctg atatagagac tctaattgaa tctggaattg taacaatgaa taaagaagca
    44461 tgtgaaatat gttaataaac atgtgaagta tgttaataaa taggagggaa ttttatggat
    44521 tttagattaa cagaagcaca attaatgctt caaagagtag caaaagaatt tgcagagaat
    44581 gaaatagcac caatagctgc tgaaacagat aaaacaggta tttttccaag ggagcttttt
    44641 agcaaaatgg ctaaaatagg atttaatgga attggaacac ctgtagagta tagtggttct
    44701 ggtggggcag atatagaaaa ggtaattgtt gttactgaga ttgccaaaaa atgtgcagca
    44761 tctgcagcaa tattatcaat acacacaata tatgctcaag ctattttgaa atttggtact
    44821 gaggaacaaa agaaaaaata ccttccaatg atggctgaag gtgggtgtgt aggtgctttt
    44881 gccttaaccg aacctaatgc tggttcagat gctgcgagag ctgcaacaac tgcaattatt
    44941 gatgaagaaa ctgatgaata tgttttaaat ggaactaagt gttttatttc tggtggaggt
    45001 caagcagaat cattaataat atttgcattg acagacccat caaagggaat aaagggaatg
    45061 tctgctatca ttgtcgacaa aggtactcca ggtttttcaa taggaaaaat tgaagaaaaa
    45121 atgggtattc atggttcaga aactgcagag ttaatatttg ataactgtag agttccaaag
    45181 tctaacttat taggaaaaga aggtaaagga tttaatatag ctatgacttg tttagatgga
    45241 gcaagaattg gagttggagc tcaagctgta ggaattgctg aaggggcttt agaagaaagt
    45301 atcaaatatt ctaaagaaag agtccagttt ggcaagccaa tttcagcttt gcaaggtatt
    45361 caatggtata tagcagatat ggcgacaatg gtggaatcag caaaattatt agtatattat
    45421 gctgcagatt tgaaagctag aggagaaaaa cacactaaag aagctgctat ggcaaaatac
    45481 aatgcgtcac gtactgcaag agaggttaca aatttagccc ttcaaatcca tggtggatat
    45541 ggatatatga aggattatcc attagagaga atgtacagag atgccaaaat aacagaaatt
    45601 tacgaaggta cttcagaaat acacaaagtt gttatttcaa gagcagtact aggataggag
    45661 gaaaagaatg aatatagttg tttgcttaaa gcaagttcca gatactaatg aagttaaaat
    45721 aaataaagag acaggtactc taataagaga tggtgtacca agtataatca atccagatga
    45781 tagaaatgct ttagaagaag ctctaaaaat gaaagatgaa ctaggagcag tgattaaggt
    45841 tataagcatg ggacctcctc aagctaaaag tgctttaaaa gaagctttgg caatgggagc
    45901 tgatgaagct tatttaatct cagatagagc ttttggtggt tcagatactt gggctacatc
    45961 tacaattatt gctgctgcta tagagaaggt tggaaagtat gatgtaatat tctgcggaag
    46021 acaagctata gatggagata cagctcaggt tggaccagag gttgcagaat ttttagggat
    46081 accacaagtt acttatgcga aagaagtaaa ggttcaagat gacaaattac tagtaactcg
    46141 ttatacagag acaggggatt atttaataga agcaaagatg ccagttttat taactgctat
    46201 aaaagagtta aacaatccaa gatatccaag tgtcaaggga atcttagaag cttataataa
    46261 tggagatgca aagattactg tattaacact tgcagattta gatgttgata caactcaaat
    46321 tggattaaag ggttcaccta caaacgttta taagtctttt gtaccagtta aagacaagca
    46381 taatgaaata atagaaggta taaataaaaa agaaaaagct gagaaactaa tagaaatact
    46441 attcgatttg aaactagtat aggagtgtta agatgatgag agcaaaagtt aatcaaggta
    46501 taaatttaaa tgattataat ggtgtttggg taataggaga gcaaagggaa ggtaaaatta
    46561 atcctgttac gatagaactt attggtgaag gaagaaagct tgctgaccaa ttaggaaaag
    46621 agcttgcagt tgtgatagct ggatatgaag tagagaaaga agtgaaggaa ttacttcact
    46681 atagtgttga taaagtatat tacatcaatg accctcttct taaagatttc actactgatg
    46741 gatatgcaat ttcaattgca aatttaatcg aaagaaaaaa gccagaggtt gtattggttg
    46801 gtgctacttc tataggaaga gatatagcgc ctagaattgc aggtaaggtt ggaacaggtc
    46861 taactgctga ctgtacaaaa cttgaaatag attcaacaga taataagtta ttacaaacaa
    46921 gaccagcatt tggtggaaat ttaatggcca ctattgtttg tccaaaaaat agaccacaga
    46981 tgtcaacagt tcgtccagga gttatggcaa aagctgtaag aaacgaatca gagactggaa
    47041 ttttagaagt tgttactcca gaacttactg aaaaaatgat tagaactaga ttagtagaga
    47101 tacttccaca agaaaagaaa tctgtaaatc taactgatgc tagaataata gtatcagggg
    47161 gaagaggatt aaaaagagca gaaggatttg agcttataaa agaattggct gataaattgg
    47221 gggcagagat tggtgcttca agagcagcag tagattcagg gtggatagaa cattctcatc
    47281 aagtgggaca aacaggaact actattagac cagaactata cattgcatgt ggaatatctg
    47341 gagcaataca acatttagca ggtatgagtg attctaaata tatagttgct ataaataaag
    47401 atgcaaaagc ccctattttt agtatatgtg actatggaat agtaggagat ttatatgaaa
    47461 ttatacctga aatgatagaa tcattaaata ggtaactttt agaaaacatt gaatatgtag
    47521 aatgataagt cttataatat tgtattgtaa gacttattat ttttgctgaa ggttatagtg
    47581 gggagatgaa acaatgaaag agcagtggta taaggatata tttgcaagag tattatctat
    47641 gactgatgat ggttttattg ttgtaaatac aagtggagta ataatagata ttaatgataa
    47701 atattgtgac tttttaggaa aagaaagaaa agatataata ggacaaaata tacaaagtat
    47761 tataccaaat acaaaaatgc tagatgttat gaaaaataag tattgtgaag aaggagctat
    47821 acatcattat tcaggtggaa atacaaaaga aaaaagtgta atagtaagta ggtcttatgt
    47881 ggaaaatgac aatggagaag tagttgcagg agtagctcaa gttaaattta gattgcaatc
    47941 atttgatgta gctaaaaagt taatgtcaga atatatggag ctccaatatt ataaagagca
    48001 gtttaaggat aactgtggtt ttgacaagct cataggtgaa aatagagact tcatagaact
    48061 taagaaaaca ggtgtgaaag cttctaaaac aaactttcca gtacttttaa cgggtgaaac
    48121 aggcacaggt aaagaagttt ttgctagagc aattcacaat aatagcagta ggtcagataa
    48181 acctatggtt agtataaatt gcgctgcaat accagaagaa ttattagagt cagagctatt
    48241 tggctatgac gaaggagctt ttacaggagc aaaaaagggt ggtaaaaaag gtaaattttt
    48301 agttgcgaat aatggtacaa tctttttaga cgagataggt gacatgcctt tgaccatgca
    48361 agcaaaactt ttaagagttc ttcaggaaag tgagatagaa ccagtgggag gtcttaaaac
    48421 tataaagata gatgtaagag taatctctgc cacaagaaag aatttaagta aaatggttga
    48481 agagggatta tttagagaag acctatacta tagattaaat gtaataaaca ttcatatgat
    48541 ggaattgaag gacaggcaag atgatatttt attgctagca aattatatat taaacaaatt
    48601 aaatgttgaa tacaaggaat tgaaggtttt aagtgataag gttaaaaatt gttttattaa
    48661 ctatacttgg ccgggaaata taagagaact acaaaatgta ataaaaagtg cctatgctgt
    48721 aagtgatgat atggtcatta tgatgtgtga ccttccatct aagatggata atatcagcag
    48781 agtagctcaa tgtaatgtgg atagcaattg ttcaattcat gaaatggttg agaattatga
    48841 aaagagctta attattgatg tgttaaggaa gtataattgg aaatgttcta aggcagcaga
    48901 ggttatggga atacacaaga gtcttttata taagaaaata aaaaagtatg aaattgaatt
    48961 aaataattaa gataacttga attaaggcaa tgctaaaaaa gcgcccttat tcaaagcgaa
    49021 ctgtataaac tgttttatgc agttaaaacg tgtaaaagta gatgtgaagt actaatgtca
    49081 atcattagta cttttttatt atatttataa ttactatcta tatttcagta tcttttgata
    49141 tctaagatta ttatgtttaa tttagtatat aacaaaaccc tcttagttat ggacagtttt
    49201 ttatatttta actgtctact aagaggggat agtttagttt aaatttagag taaattttat
    49261 ctagcattta taaaaaatat tttgaatagc ttttttgtta tttagtcata attttctact
    49321 tctttatcaa gttctttgcc acaagaatca cacttatata tagcattgta tccgtaatca
    49381 tattcatcaa ctattttctt ttgtctaaat acaccaccac actcacatag gaaaccaatt
    49441 tttataagtg taacgataaa ttgtgatttt ataaatttta tatcattgca tttatcgtta
    49501 gtgtaaaatg tataaatata agagttatcg cactcatctc ttaattcaaa tctttcaata
    49561 tatgtgttat tttttaattc ctcaaattct tctttagtta aatatgattt ttgttgcaat
    49621 tcatgtaaac gcttaatttg gtccattatt tatatcctcc caataatttt agtattttaa
    49681 gcttagataa ggaatctaag ttttattaaa tttatcccaa ggaattattt aaatcatatt
    49741 tagttttatt aattacaaca tatataaatt acacgaaaat aaaactaatt gtaaaaataa
    49801 tatcctgtga aaacctaaac tactaacccc ttactaaccc gaaaactaaa aaaagaaaat
    49861 atatccaaat ataagtgata tataaataaa gatgtttcat ataaatttaa ctttaaatat
    49921 tctgacaata atatatataa atatattata gttaaaatat accacatatt ttgggtattg
    49981 tatactggaa ttagagtaat taatttattt tttaacatac aaatgatttt atgaaaaaaa
    50041 acaagactca aaaattttta tattctttga tagaataaaa ttgagagtaa atttattgaa
    50101 ttttataaaa tttataaggg gtgagtctaa gatatgcatg aagataaaaa tgatatattt
    50161 gaatcaatag atactgagga ttttgataat aaaacagaag aagaatgttt agagctagta
    50221 agaaaaaatg gattgaattt aatatacata aaaaatcaaa cagaagagat atgtctagag
    50281 gctgttagac aaaattgtaa tgcaataaaa tgtgttcaga atcagacaga aaaaatatgt
    50341 atagaagcag ttaaacaaga ttggagaatg ttagaatttg tggaagagcc aacagaagaa
    50401 atttgcatgt tggctattaa ccaagatgga acagcattaa aatatataga aaatcagaca
    50461 gaggagttat gcttaagagc cgttgaaaaa aatggtgcag ctttggagta tgtaaaagaa
    50521 caaacagaag aaatatgtat agaagcagtt agaaacagcg aatttggatt ggcaagagtg
    50581 aaaaatcaaa cagaaaaaat atgtatggaa gcagttaagc attgtagcta taatctaaaa
    50641 tgggtagaaa atcaaacaga agaaatatgt atggaagcag tgagacaaaa tgggcttgat
    50701 ttgaaatttg taaaaaatca aacagaaaca atctgtttaa gagcagtaag acaaaatgga
    50761 atggcattag aatttgtaaa ggaacagact gttggtatat gcttaaaggc agtaagacaa
    50821 tatggaatgg cattaaaatt tgtaaaggaa caaacagaag aaatttgtac agaagctata
    50881 aaacaagata aaagagcact tagttttgta aaaggagata aggaaaaata taaggctcta
    50941 tatgataata atgaaccatt tgcaaagaga tatgttagaa atgtaataga aaaagaaaac
    51001 agagcattga ttaaaaaagg agaagaaaat gcaaaaatca aaattgcagg aaaactttat
    51061 gatagaggca tgtcttttga agatatatca gatatagttg agattgaaat aagcaagtta
    51121 aaagtgagtt taggtgtttt ttaaagtaat aaatgtaggt gttttttatg ggaaatagtt
    51181 aataaaaaaa taatcgacta gctctttgta ggacagcaaa attagtgata taatttgatg
    51241 tataataaat tatttttatt agataagggg gaattaaagt tgaagattac agtattatac
    51301 caaacaagaa gtggaaacac agaaagggtc gctaagctga tagaagaggg cgctaaaaag
    51361 gtggatggag tagatgtaaa gcttatgaga cttgataata ttgatttaga ttatttaaat
    51421 gaaagtaaag cagtaatatt tggaacacct acttatttag caaatacaac ttgggaagta
    51481 aaaaaatggt ttgatgaaga ttcaaaaaaa gttaatttag ctggaaaatt aggagctgtt
    51541 tttgctacat gtgattatat atgtggaggt ccagatgttg cgatacttac tatagtagga
    51601 catttgatgg ttaaagggat gcttgtgtat tctggaggtg gttctttagg aaagccattt
    51661 atacatttag gacatgtaca ttcaattgaa ggtccagagt tacaagatga gaaggctata
    51721 atatttggtg aaagaattgc tactaaggca aaagaactat ttgcttaatt tctatatgca
    51781 tagtaatgat tagagtaaat ttagggtttt aatggagatt tgaagtaaaa gttataaaat
    51841 aaaaaatttt ccataaaatt actcaagatg aattataata taattataaa taaattatat
    51901 tattaaaata tttaaaatca aacgtcaata gcgagggaag tttatggtat ggcatataga
    51961 atatgagatt ttttctgcaa ttatagttat ttttttaatg gtatactttt ttagaagtaa
    52021 atttatacct actttacaaa acaaaatata ttgtgcactt ttaatattct catttttatt
    52081 tataatttca aatattttag gttcattttg tctaaataat atagacaaaa ttccaatttt
    52141 tattactttt ttattgaatc agatatactt attgttattg ccaataccag cagcacttgt
    52201 atcattttat gttatggcta ttatttatca agatataagg tatatgaaaa aaagattatt
    52261 atttttatct ataccactta taatttgtat aatcttatct attacaaatc cttttacgca
    52321 tattctattt ggattgtcaa aagaaacagg ttatatacga ggttgtggat atgttgcaac
    52381 ttttgcatct tttttctttt atgcaatata ttcagcattt ttatctttta aatatagaaa
    52441 agcaatgcat gaatcaaaaa tatgggctat tagaggtttt cttatagttt caattgtggc
    52501 aattatctta caggcaattt ttttacagta tcttcttaca ggaactgcat gtgcatgtag
    52561 tttacttttg acatatcttt ctatgcagaa tcgaggtctt attattgatg accttactgg
    52621 tgtactcaat agacaatctt ttattcaaga gctagatttg aatatcaata ctgaacaatc
    52681 aggatttatt attacaattg cgcttgatga ttttaagttt atgaatgaaa cttttggaac
    52741 aaaaaatgga gatattgcac taaaagaagt tggaaaatat ttgattcaga tacatgatgt
    52801 aaaccatgta tatagaatag ggggagatat attttctatt gttgtcaata gtcaattagg
    52861 tatagaacca gatgatatta tcagaaagat agaagaaaga tttaaaaagc cttggctagt
    52921 agaagagata agttttaatt tagcaactag tattgctgtt gtttattacc cagaaaatgc
    52981 agaaacgaca gaagatgtaa ttgttgctat agatttctct atacatgaag caaaacgctc
    53041 tgagtcaagg cgagttgttt atgcagatgc gtctataagt gaaaagataa agaagaaaca
    53101 tgttattaaa aattgtttaa aagaagcatt aaaaaatgat gggtttgaag tgtactacca
    53161 acctatattt tctaatagca ggggcaggtt tacttcagca gaggcattac ttaggctaga
    53221 acacaaagag ttaggtttta tacctcctga tgaatttatt ccaattgcag aacaaacagg
    53281 attgattaac tcaattggat tagtagtctt tgagaaggta tgtagattta tagctagtga
    53341 tgagtttgaa gatttaaaat tggataatat agctgtgaat ctttctgtag tacaatgtat
    53401 gcaaaaaaac ttagctgatg atttacttta tcttatgaat aaatataatg tatcaccaac
    53461 taaatttaaa cttgaaatta ctgagactgt ggctatgggc tcttttaata taattaaaga
    53521 aacaatggaa agattaattg atttaggtgt taagtttgca cttgatgatt ttggaattgc
    53581 ttattctgga gttactaata tgctttcttt accattttca gtaattaagt tagataagag
    53641 tttgatttgg tctatgaatg aagatagtag gcataaactt acagttgaga cgattatagc
    53701 acttataaat aaattgaata tgaaggctgt agcagaaggt gttgaaacca ttaagtgtgc
    53761 tgaagattta atagctatgg agtgtgaata tttgcaaggg tattattttt ctaaaccagt
    53821 tccagaagat gtttttaaaa atttgttgaa agaaaatact tttacaagtt aacacccttt
    53881 atttttttaa ttacaacttt gttcattgac actgccagcg atatattata aaattaacac
    53941 aataataaat attaaattta ttatacatat tattaatatt aattaatgga gtaaagattt
    54001 attatatatt ttatttaatt atcctaaagt gagaaaggaa gatgtgacat gaataaaaag
    54061 aaaatattag tgccaattga tgggacagaa agaagtatgc attctttgga atttataaaa
    54121 ggaatattta aaaaagatga agttgaagta gaaataatga atgtaaaaga actagtattt
    54181 attgatggca tatccctggc tgaagagata aaaaattctg aaaatttagg aagaagaatc
    54241 ttggataaag cagcagagat aatgggagag tatgatgtta aagtacattt tacttttgga
    54301 tatccaggag atgagataat tagaaaagca aaagaagata atgtagattt tatagttatg
    54361 acaaaatcta ctaaaaaagg tcttacaaga atgataggtt cagtaacagc aagtgtagtt
    54421 aaacaagcaa aatgtatagt gatgattgta ccggagtaga attagaaagg tatttgaaat
    54481 atgaataaaa agatagtagc agtttgtgaa agtgaaagaa gtttaaattc tcttaagaca
    54541 gctgcaaatg atttaggatt tgatttagtt tatgaaattc aagaaaatga taatataaaa
    54601 aatgaacttt ctatttatga tatagaagat gcatccatag tgttatttgt tacaagtgat
    54661 tctatagaaa gcatagagaa gattgataga tttatagata gagaatttta tgaagttgat
    54721 ccaaagtata taatagagga tgcaaaatct atagtaagtg aaattttaat agacttaaat
    54781 taatcgtggg tgtcgcacta agaatagagc gacgcctttt tatatatttt acacaagaaa
    54841 taaagaggtt gtatcaaaat atagataaga gtctttttca ttgttgaaat gatgaaaata
    54901 tatttgattt catacaaaaa agagtacctc ataactaaaa agttcacttt gagacactcc
    54961 atttttatat gttagttgca tttaaggtaa aatagaagtt taatcatgtt gaaataactg
    55021 aattacatct tctaaatgat tgtacattga tgtataacct aagtaagagt ctttactatc
    55081 aaatgcaatc attatcttgt tatggtggct aatcatatcc ttgagagaat ttctatattt
    55141 aaaaccaaag tattggttag aagaaactgt tttaggtatt aactcataat attttataaa
    55201 aattggatta tgagaagcta aaattatctc tttgtgaaat tgcaagtcag catcataaca
    55261 ttcttctatc aaaccatgag aaaccttatc caattcctct attgacttta ggtaagtata
    55321 ttttattttt tgaagttctt tagatgtagc atttaaaatt gctagtttag tagcttcgct
    55381 ttcgataagt tgtcttgctc ttaaagattc tacataaaat tcttgtatgt tatgattttt
    55441 atagatttca ccatcatcaa ataggtcaac ttttttaaat ccttcaacta taggacttga
    55501 ataaggcaca gctctaagta ttccttcctt acagagtata tttatggcat ttcttacagg
    55561 tattctactt atgttaaata ggtcagcaat ctttctctca cttggtaatt tactattaat
    55621 tttaaaagtt ccatttagaa tgtttaattt aatataatca ataatttttt cagtggcatt
    55681 taagcttttc ataaaaactc ctaaacatat aattttttta tgattgtatt atatcatagt
    55741 taagagttaa atctactttt ttataatatg tataagacag gatagaggcc aaaatagcta
    55801 taatagccaa gataaagtat ccatattgta ttgaagtata ttccgatatt ttaccaacta
    55861 tcattggaaa tacagacatt cctatagcat aaattgcttg aaaaaaaccc attgcagtag
    55921 atttctgatg ttttggtaca tttttcatag actcgctagt aaggtaagaa aggagtatac
    55981 ctgtagatat acctggtagt acttgtagta caaatattat attaatattt tttattgttg
    56041 gaactaaaaa gcaataggct gaaactaaaa taaaaactaa aggaatccaa aattttggtc
    56101 catacttagt acaaaattta gtagaagcaa agccagaaga agcaacagca cacaccatgt
    56161 aaaatataga agatagacct atgagggtag aactagaacc taagttttta agaatttgag
    56221 tagtaaatga cattgttgta gacatttgaa taccctgttg aattaatgcc ataaaggaaa
    56281 aaaatacaag tcttttatcc ttgcagatag ataaatattt tttaattgat attttttcag
    56341 gtattttttt agaattatga ttttttatat ttaaggctag aatcgttcca ataactgaag
    56401 acaatacact catgatacat aaggctgtca ttcctaattt ttcataaaat aaagtactca
    56461 taacaaatcc aatcaacatt cctagattgt ttaccaatat tatcgtactt gtagcttttt
    56521 gttgatgttc tgtagaaaaa aagttggtat agtgaaccat gtaagaaatc caagttgatg
    56581 atgatattcc agataaaatg ttagctataa gaaaaccatt gcctccagga gaaaagactc
    56641 ttataagaga tgctaaacca gcaaagaaaa ttccagacag tataaatatt ttatgtttat
    56701 ttatggaatc agcaaatact ccaacaggaa gccttaataa acattgtgat attccatatg
    56761 cacctattat tataccaatc atatttgtag atacattaca tgcacttaaa tatggatttt
    56821 ggaaaggtat atatacatat tgtgaaaacc agaaaaatgt aacaatagaa agtaaaagta
    56881 atttttgatt agatattttt ttcatattat cctccatgtg gtatttttat aatgcaaata
    56941 atataccatt tagatttttt aatcaagtac tttctctatt aaaaaaaatt taaatatata
    57001 attattattt acaaaaaaat tatactttat agttgaatta agaaaacgct tatgatacta
    57061 taaagttaac aaatttgaat atataacagt agacgtgtta ctggtaatgc aggcaagatc
    57121 gaatcaattt ttatagatta tctatagagt actatgggta taatctattt atttggttcg
    57181 atttttttgt ttaattggcc ataaaacaaa aagcctatag ttgaaaatgg aggatttttt
    57241 atggattata aaaatatagc tcaagaaatt ctactaaatg taggaggaaa agagaatgta
    57301 aatgaagtga ctcattgtat gacaagactt agatttaaag tcaaaagcgc ttctaaagtg
    57361 aataaggata aattatctaa aactgaagga gtaataactg ttgttgagag tatgggtcaa
    57421 atacaagttg taattggaaa taaagtaaaa aaagtatatg atgaggtcat aaaaattgta
    57481 cctcaatcaa ataacatagg taaaaagaat gaaagtcaag aaaagcaagg tataattaat
    57541 tctatattat cagcagtagc tggtatattt acacctacaa tacctgctat agcaggggtt
    57601 ggtatgatta aaggtatttt atcagttctt gctatgtatt atatgaataa aaatggagta
    57661 gatataaaag aaacgcaaag ctatattatc ttaaatgcta tgactgattc tatattctat
    57721 tttatgccta ttatactagg atatactgcg gctaaagtat ttaatgcaaa taaaataata
    57781 tctatggtat taggagctac actttgttat ccaactttta ctgctttgat ggcaggtgaa
    57841 gaatctgtta gatttttagg attggcagta acaaaagcta cgtatacatc atctgttatt
    57901 ccaataatta ttgctatatg ggctctttca tacgttgaaa aagtattaga aaagtatata
    57961 cctgaggtaa ttaaaataat aatggttcca actttatcat tggtagtaat gttacctgca
    58021 acattatttt tatttggacc aatcggaatt tatataggaa atgtcataaa cttttcttat
    58081 aagtatattt atgaattaag cccagcattg tgtggagcat ttgtaggtgg gttatggtgt
    58141 gtgttagtta tatttggtgc tcatagagca ttattaccaa taggtataag tgatgttgct
    58201 caaacaggaa gacaaaattt attggcgttt gcaggagctg caaacttttc acaagcaggg
    58261 gctgctctag gagtattctt taaaactaaa aatcaaggac taaaaacaat ttctatgtct
    58321 gcaactataa cagctttatt tggtataact gaacctgcaa tatacggtgc caatcttaga
    58381 ttaaaaaaac ctatggtatg tgccgtaata tgtggtgcat ttggaggtgc gataatggga
    58441 atgggtggag cttatggtaa tgcatttgca aaccaaggtg ttttaactat acctgtatat
    58501 gctgaagcag gtgcattagg tttcttaagt tatctaggtg gttgtgctat agcatttttt
    58561 ggttcagcta tttcaactta tctagttgga tttgaagatt tggaagagtc ttctaataag
    58621 gaaaattcat ctataaaagt agaaacgaag gatggtgtta ttgatataac ttcacctgta
    58681 gagggcgaat gtatagaatt gtcagaagta aaggatgatg tatttgcttc aaaagctatg
    58741 ggagaaggta tagctgtgtt acctacaaaa ggagtaataa cagcccctac tgattgtgaa
    58801 gtagcttctt tatttccaac attacatgca ataggattaa aattagataa tggagcagaa
    58861 atgttaatac atgttggaat caatacagta gagttaaatg gtaaatactt tacaaaacat
    58921 gttaatcaag gagatttagt gaaaaaaggt gataaactta tatcgtttga tatagataaa
    58981 ataaaaaagg ctggttatga tgtaactacg ccagttatag taaacaatac atttgatttt
    59041 gggcaagtag tttcttgtaa atctagttat gtttcaacca atgataatat aatttcatta
    59101 gtattagctg gtaattaagt taatttgact agagataagt aaattgattt aaaaggaaat
    59161 aagtaaatca acaattaaat acatctaaaa gtaagtttat tgcaatgaat tgttaaagaa
    59221 aataattaat atggagtaaa tctattgcaa tgaagtaaca aagaaaataa ttaatataga
    59281 gtaagtttat tgtaatgaat tgttaaagaa aagagttaat atagagtaag tttattgtaa
    59341 tgaattgtta aagaaaataa ttaatatagg gtaaatctat ctcaatgaaa taacaaagaa
    59401 aagagttaat atagagtgaa cttattgcaa tgaatcaaca aagaaaataa tcaatataaa
    59461 aaggagaaat atttatgaat acaggatttc caaaagactt tttatgggga gcatcatctt
    59521 ctgcatttca agtggaagga gcttgggata aagacaataa aggaaaaacc gtagccgact
    59581 ataattcttt taaaaagtct catttacagg cagatactaa agtcgcatca gacttttacc
    59641 ataattatga agaagatatt gaattaatga aagaattagg gatgaaaaca tatcgttttt
    59701 caatttcatg ggcaagaata ataccagatg gtgaaggaga gataaaccag aaaggtttag
    59761 aattttataa taagataata gacaaactga tagagtgtga tattgagcca ttcgtaactt
    59821 tataccattt tgaccttcca tttaaattag tagagaaata taatggttgg gaaagtagag
    59881 aaactgtcta tgcttttgaa agatttgcta aaatatgctt taagcatttt ggagataggg
    59941 taaagtattg gcaacctcat aatgaacaga atttaattgt tagagtggag gagagaatta
    60001 atatatatga tgaaacagat tcatggaaga tagataaaat gcgtgctcag atggattata
    60061 atctttgctt agcacatgca ttagcagtca atgcatgtca tgagatgata aaagaaagta
    60121 aaattggagc agcagtatca tcatctgtaa catatcctct tacttctaag ccagaagatg
    60181 tatatgcagc tagaatgaat gataatttta aagtgtacta tatgcttgat atgcatcatt
    60241 atggagaata tccagggtat tatatgaagt atcttgaaaa aagaaatata gttcctcaca
    60301 tggaagatgg ggataaagag atacttaaaa aagctaaaat ggattttata gctgtaaatt
    60361 attataggac aaattgtgca gaagctttac ctgaagattc acaacatcca tttggattaa
    60421 gagaaggaac tgttgatttt agtatgtatg gactatttaa aatgtcaatg aatcctaact
    60481 tagaggcttc tgagtatgga gcagcaatag acccatcagg tcttagagtt gccttaaatg
    60541 aatattggca aagatatcac ttacctgtta taataacaga aaatggtcta ggagctaaag
    60601 atatattaga agatggaaaa attcatgatg actatcgtat agactattta agaagtcata
    60661 taaatgcatg taaactagct attgaagatg gtgtagagat gattggatat tgtccatggt
    60721 catttacaga ccttttaagt tcttctcaag gttttaataa gcgttatgga cttgtttata
    60781 taaatagaac tgaccatgaa gttttagatt taaaaagaat caagaaagat agtttttact
    60841 ggtataaaga agttatagag aacaatggaa tagtaaaata aacataaata tatattgagg
    60901 gttttagtat gtacattaca aaggtattaa ataattcgtt gctacttgca aaggatgata
    60961 atgatgaaga aataatattg atggggaaag gcattggcca taattataag gccgggtctg
    61021 agttaaataa aaaagatata gaaaagattt ttgttcttca tgatgaaaat ataaaaaaga
    61081 gtattataca attggcaaca gaaatagatg cagaatattt tggtatagct caaatgataa
    61141 ttgcatatgg aatagaaaaa tataacttaa aacttatgaa ccatatatat ttggccttaa
    61201 ctgaccacat tgcctttgca gtgagacgtt ttaaagaagg tataatgatt gaaaatcact
    61261 atttgttcga aatcaaggaa tttaatccaa aagagtatga tataggaaaa tatgctatta
    61321 ctgtttttaa ggaggttctt ggtttagacc taccagaaga agagattggt aatatagcag
    61381 gccattttat aaatgcacaa caagataatc cttatagtga tagaaataag agaagtgcta
    61441 aaattgtaaa tgctattttg caaatagttc attatcactt ttctattgta tataataaag
    61501 agtcatttta ttataggaga tttgtaatgc atctaaaggc cttttcacaa agatttctgg
    61561 ctaatgaacc atcaagagaa aaaatagatt ttatatatga gcaagttcaa aaaaattgta
    61621 aggaagagta tgaatgtgtg aaaaaggtag gagcttatat gtataaggaa tactccagag
    61681 aattaccaag acaagaggag ttatatttga tgattcatat tcataagatt ttaggagaat
    61741 tatgcgaaaa tagttagaat atcttaatat gctagtaata ttataaaaaa ttaaaaatta
    61801 actgcacttt aaatatgaat aattgcatta cttaaggggg ttgtcttaaa attgattttt
    61861 ttaattaaat ttgaagctca actccttttt taaaccttta tatcattaca actttaatgt
    61921 ttatacgact gtactttaga tgtatatcta ctttttacat ttctcaacat gcaaacctac
    61981 cattttttgc agtatgttaa ttgaaataaa ccattgagtt aaccctaaat ttattctgga
    62041 cttataggaa tagttccaaa gatactttaa aatattttct ggaataattg cttatttcac
    62101 atatgtttta ttgtgatgtt ttgatttaat aaattcttca actctgtata tagtaaatgt
    62161 attatcatgt ttgttttatt caagcacact tataatacgc ttgatttttt cacaatgatg
    62221 aaatatacta atgggtgtta taggtataag aatcgcatta cacttgaaga agtaagtgat
    62281 aaatgaggta taaatcctca tatgataaac tactatttca ttgaggaaca tattctaagt
    62341 gatgtcaaga tactacaata tgactaaatt cctagtgata aaaaagtcta cgaatgagtg
    62401 tagaaagggg aactaagatg aataaagttt taattataga tgatgataaa gatctttgta
    62461 ttttgttaaa aaagagtatt tcaattgaac agattgaagc aaactattgc cattctggga
    62521 gagatggact ggttgaactt tcaaaacaag attatcagtt agtagttcta gatgtgatga
    62581 tgccaggtat ggatggtttt gaaactatgg aacaaatacg aaaatatagc agtattccca
    62641 tcttaatgct gacatcaaaa agcgataatt acagcaaagt gcatggattg cgagctggtg
    62701 cagatgacta tctaaccaaa ccatttgaaa ttacagaatt tactgctcgt gtactgtctt
    62761 taatccgacg ttacacccgt tttaatccaa aaaatgagga gccacagcaa ctttctttca
    62821 aaggtttgtt gattgacctt gaccagcata cagttactac caatggcgaa cctatgttgc
    62881 ttccacccaa ggaatttggt gtacttcttt actgtgcaag gcatcagggt aagattttga
    62941 caaaacagca gatttatgaa gccgtgtggg gtgagccata tgtatatgat gacagcaata
    63001 tcatggctat tatcagtcgc ctaagaaaaa aaattgaact agacccatca tctcccatct
    63061 atttgcaaac aataaaagga attgggtatc aattcaacac ggaggtatga aaatggatga
    63121 acaaacgata attcttttct tactcttgct gtcgattggt ctactttttc tttccatatt
    63181 tgctttttcc aagcttgggc atatttacaa gcgcctaaaa gatatagagg agatactggc
    63241 tgatgtacaa attggagacg aaaatcgtaa aatactaatt aagccatgtg atgttatggc
    63301 tccattggtt tatcagctta atgagattgt ctacgattat gaaaataagt tactttctct
    63361 gaaaaagtcg gataaagcta gcaaacaact tatgacaagt ttatctcatg atgttcgtac
    63421 accattaaca actctgattg gttatctgga tgctgtacac agtggtatag ttatcgaaca
    63481 agagcgggag gaataccttg aaatcgctag gcgtagagcc tacgacctca aggattacat
    63541 tgatgttctt tttgactggt ttcggttgaa ctctgatgaa tttacgctgt caatagaatc
    63601 tgtggaaatt gcagagttgt cacgcaatat tttgaaagac tggattccta tattccatga
    63661 aaagaaactg aattttgaaa ttgatattcc agaaaatcga ctaatggtaa acctcgaccc
    63721 agatggatat tcccgtgtgg tcaataatct ggttcaaaat gttcttgctc acagtaaggc
    63781 tcggcaaatc aagattacca tgagtgagga ttccagaatg gtattactcc gtgttgagga
    63841 tgatggtgtt gggattgcca gagaaaattt accacatatt tttgagcgac tgtataagtg
    63901 tgataaagga cgttcagaaa aaggaagtgg tcttggtcta tctattgtca gtcaaatggt
    63961 ggagcgaatg ggtggtcagg tttccgtaga aagtgagatt ggaaagtata ccgtatttac
    64021 agtgagctta ccattaatat aaaattgttt ttcccccatg tgacatgtat acacatgggg
    64081 attttttgta agttataaag ttgcaaggtt aatacaaggt tgttgcaagg ttaatgtaag
    64141 attgaggtgg tatgataact ttaataaaca aaggaggctt ttattattta tgaataattt
    64201 aattattgaa acaaaaaatc tcactaagca atatggtgct caaaagagcg tttctaattt
    64261 gaatattcac gttcagaaag gtcgcattta cggattgcta ggaagaaacg gtgcgggtaa
    64321 gacgacaact atgaaaatgt tattgggtct aacaaaacca actactggag aaattaaaat
    64381 atttggtcag gacattcaca ataacgagaa gaagcttctt cctcgaattg gatgtttgat
    64441 tgaatcacca gggttttatc ctaatctgac aggaacagaa aatctcaaaa tctttgcaag
    64501 gcttagagga ataccaaaaa aaaatgcagt agaatcagca ctggatgtag tcggtttgcc
    64561 aaacaatgac aaaaagttat tttctcaata ctctcttggt atgaaacaga ggttggcgat
    64621 tgctcttgcc attatgcatg acccacaact gttgattttg gacgagccta tcaatggact
    64681 tgatcctatt ggtattgcag aagtaagaac gtttattcgt gatctctgca cagaacgagg
    64741 taaaactatt ttgatttcca gtcacattct ttctgaaatt gccttgttgg cagatgacat
    64801 tggcattatt gaccatggta ttttgttgga ggaagaaagt cttgcccaat tagaagaaaa
    64861 aaacagtaaa tacatacatt ttgctgtatc tgatgcagca caggcagcaa ggcttctgga
    64921 aacccaactt aacctgaaaa atttcaaagt agcagataat tacaatatta tgctatatga
    64981 tacagatgtt tctgttgcag aaataaatcg tgctttcatt ctaaacaaca ttgaggtatc
    65041 agaatctcat ttatgcgaag atactcttga agattacttc aagaaagtaa cagggggtga
    65101 aggaattgct tgatataatt tcatgtgaat tttcaaaact caagcggtta aaatttatac
    65161 tgatttctat tttaggtgct tgcttatttc caattcccgc aacaattttg attgcaaagg
    65221 acaacttgcc ctttgagcaa ttgttcaaat tagttgtcaa ttttggatat tttttgctat
    65281 taccaattgt attaagtatt gttgctagcc aactattttt tatagaaaga gataatgatg
    65341 tattaaaaaa tcttgcaaca gtgccagtgc aaaaaggaaa actggctctg gcaaaattgg
    65401 ctgtgttgct gtttatatca ttgttctact ctgttgcagg gttaggagct actatcattg
    65461 gaggtttcat tgttggaata gtagaggggg ttgctgtaaa attaggaatg agcattgctt
    65521 ttggaattat gttttttgtt actgtacttc ctgttgtggt actcattgta tatttcaatc
    65581 gcagctatat tttttctatt atactttctt ttgtatatgc tattttcaat tttagtatat
    65641 ccttaaatat tatcaatttt gaaccaaata acccaatatt aagtgtatta cctgctcctg
    65701 ttataatgcg ttggtggatg gcattttggg gagatcccac tggcgaatac acggcactta
    65761 gacagccata tttgctctca actcctgctt gtgtaggtat tttatgtttg ataaccatta
    65821 tagcagtcct gctgatttgt atgatataca aaaagcagga gaattaggag gtatctatgc
    65881 ttgatataat tactacagaa tttcaaaaaa taaaaagata taatattcta tggattggtg
    65941 ttgttgctgt tctgttttca gcactattgg cagtttttca ggttgtaagt tcacacggca
    66001 gtgaccctct aacgtatgag agctttgcaa acggagttat ctggaataat ttcagtctta
    66061 gttttccatt tgggattaca cttattggag gatatcttat taaccgtgaa tatacagacc
    66121 aaaccttaaa aaacatccta actgttccta tttcattacg caaattgcta gtgggaaaat
    66181 taattgcggt tggaggaatt actgtattgt taagtctttt cagcttctta tgcacattta
    66241 ttttggggtt gttgttttgc aatatcaata tatctgttac actcgttgta aaatccttag
    66301 ttcagatttt gtctgttaat ctgtattgtt atgttgctgt tttgccgatt attgcttatt
    66361 ttggtcgtaa acaaaatgca tttctgacgg gtgtagggat tgcatttgta tacggttttt
    66421 gtggtgtgtt tgttgctgga agaaatctga cagactttta tccaatcaca gcaggtcttg
    66481 gtctagttgg atacaacaat ggtgctggta ctgtttatca gccacttatc ggtgctatga
    66541 ctttgattgt aattctaatc ttgacaacta ttctacttgt atttacacct aattatgata
    66601 aagttatgac catatctaag aaaaaaggga taaagcataa aaagtattct cataaataac
    66661 ataaatattg tttctattat ttaagttgct agacagtgaa aagaaaaaat ctgtcgtaca
    66721 gtgtctatat gctcatgtat tcaagaagct acagttttga tttttcataa ctgtagcttc
    66781 tttttgtatt tattaaatca cgactatcat aatacttgca ataggtatag cgacaagaga
    66841 gagtactgtc atatgtgttt tatatattac attaagtata ttctaaaata tatgttttaa
    66901 ataatatatt tgaaaatagg aatatttaaa taaaaaaaat aatattatat atagttgaca
    66961 aaaattggca aatgagataa tatataaata tagaaatagt aatcattact attattaaaa
    67021 agggaggaat taattatgaa cttaaaagga actaaaacag aaaagaattt aatggcagga
    67081 tttgcaggag agtcagaagc aagaaataaa tatacatact acgcttcaaa agcaagaaaa
    67141 gaaggttata atcaaatagc tgctatattt gaagaaactg ctaacaatga aaaggaacat
    67201 gctaaattat ggtttaaact tttacatgat ggtatgcctt caacagagga aaatttaaag
    67261 gatgcagcag caggtgaaaa ctatgaatgg actgatatgt atgcaaaatt tgctaaagaa
    67321 gctagagaag aaggatttga caagatagct tatttatttg aagctgttgg aaaaatagag
    67381 aaagagcatg aagaaagata cttaaagctt ttagaaaact taaatgaagg aaaaatattt
    67441 aaaagagatg aagaagttgt ttggcaatgt caaaactgtg gtcatgtgta tgtaggtact
    67501 gaagcaccag aaaaatgccc agtatgtgac catccaaaag cgtatttcaa tataaaagct
    67561 gaaaattatt aaaaattatc attattaaaa aggaatgtta actatgaaat tttctaaaca
    67621 acgagaactg attttaaatg aaatattaaa taatccggtt catcctactg cggattacct
    67681 atatgaaaac ttaaaaaaag ataatccaaa tttaagctta ggaactgtgt atagaaattt
    67741 agctcagcta acggaacatg gctttataag aaaggttagt attccagggt atccagatag
    67801 atttgatggt cgaatagata atcactatca tatcatatgt gaagtatgtg gagaggtata
    67861 cgatttagaa tccgaagttc ttaataattt acaagaatta atatctgagg agacagacat
    67921 aaaaataaca tcttataaca taagttttaa agggatttgt aataattgta aaaggtgtag
    67981 ccaagtaggt tagttttcaa attctaaaaa taattaatga ggtgagttta tgtgtagtga
    68041 acaaaaattt tttatatgtg agacttgtgg aaaccttgta ggaatgatac aaagtggtgg
    68101 tgtacctatt ttctgttgtg gaaaacctat gaaggaactt gttcctaata caacagatgc
    68161 agcagttgaa aaacatgtac ctgtaattga agtggatgga aataatgtta ctgttaaagt
    68221 aagtagcaca actcatccaa tgactaaaga acatcatata gcatgggtgt atcttatgac
    68281 tgaacaaggt ggtcaacgca aatgtctagc agtagatgga gaacctgtag ttaaatttgc
    68341 tttgaatgat gatgataaag tgatttctgc ctatgcttac tgtaatttac atggattatg
    68401 gaaggctgaa ctgtaatatt taaataaatt gagtcaaaaa ggaggctata aatgtatttt
    68461 catacaaata gcctcctata aatttatata aattcaagtt ttaattttgt ttaatgtcaa
    68521 tataatataa ggagaaaata atatgtcaat ttataaatgt agtgtttgtg gatatattta
    68581 tgatgaatct aagaatgata aaacatggga tgaattaagt gaagattggg aatgccctgt
    68641 atgtacaaaa ggtcgtagtt attttggaaa gataagtact gtttactatg aagaagatga
    68701 aaagatagca gaagacatag ttgaagatga atctaaatta aatactgaaa aagagggaga
    68761 tttaaattac ttaagtacat atttaagaag agatgatgaa gttgagaaac atatggatat
    68821 aattcacgaa atggctgtta caggaaaatc tataatagaa cctatgagaa ctaaactacc
    68881 agtaatttct tgggatgata ttttaattat gggtgctcaa ttaaatccat tacctttaaa
    68941 tgagcatgat gaagtaaata caacaacaat aataggaaaa aaagcaaaga aacctatgat
    69001 tatagaaaat ccagtttata tttcccacat gtcatttgga gctttgtcta aagaactaaa
    69061 aatagcttta gcaaagggtg cagcccaaaa taagacagct atgtgtagtg gtgaaggagg
    69121 tatattacca gaagagaagg aagcttcata caagtatatt tttgagtatg taccaaataa
    69181 atatagtgta actgaagaaa atcttaaaaa ttctgatgct atagagataa aaattggtca
    69241 aggaacaaaa cctggtatgg gaggtcatct tcctggcgaa aaagtaactg aagaaatagc
    69301 aaaagtaaga aataagcctg taggtcaaga tgtaataagt ccatcttgtt ttgaggaaat
    69361 acaatccaaa gaagatttaa agaaacttgt agatgaactt agagaagttt cagaagggcg
    69421 tccaataggt gttaaaattt cagcaggtca tattgaaaaa gatatggaat ttatagctta
    69481 tgctaaacct gattttgtaa ctattgatgg tcgtggtgga gctactggag caagtccaaa
    69541 gttgcttaaa gatgcaactt caattccaac aatatttgct ctttatcgtg ctagaaaata
    69601 catagataca catggattag atatagattt ggttataaca ggtgggcttc gtatatctac
    69661 tgattttgct aaggcaattg ctatgggtgc tgatgcagtt gctattgcaa gttctgctct
    69721 tatggcagcg gcgtgtcaac aatatcgtat atgtggttct ggtaagtgtc ctgtaggagt
    69781 agctactcag gatgaggaat tgagaaaaag attacatata gaaaacagtg ctaatagagt
    69841 ggcaaacttt ttaaatgtaa gtttagaaga acttaagact tttgctagaa tttctggtca
    69901 taaagatata catgatttaa gtgttgatga tttatatact gttaactctg aaatatcaaa
    69961 ttatacaaac atacagcatg tatagattga agtttgaaac tattagattt tagatagcta
    70021 taaaagtaaa tgataaatat attttataaa agagagtgtc ttaaaatgaa ctttttagtt
    70081 cataagtcac tctttttttt atgaagccaa atatatttat cattttagca atgaaaaaga
    70141 atcttatctc tttattttga gatagactcc ttctatttat gaaaattaaa gatattaaat
    70201 tgtaaaatat tctgtgatgt cgtactatta aactaaagat tctgtacttt aaagtaaata
    70261 aaaatttaag gagtgattat tatggaaaga ttgaagatac aagttttagt tgacaataat
    70321 acttatattg atagatactt tgttggagaa ccagcagtaa gctattatat tgagattgat
    70381 ggaaatagga ttttgtttga ctcagggtat tcagatgtat tcatatcaaa cgctgaaaaa
    70441 ttaaatatag atttaggaaa tttaactcat gttgtttttt ctcatgggca taatgaccat
    70501 acaagaggta tccagtttct agaaaatagg tatgatttat ctacagttga acttatttca
    70561 catcctaact gttttatacc tagaaaacat ggagagaaaa gcataggagc tccattttct
    70621 gctgaggaaa ttaaaaatat ttttatgtat aatcctaagg ataagccatt taatctaagt
    70681 aagaattgtg tgtttttagg tgaaatacct tctataaatg attttgaaaa aagagctaaa
    70741 attggtaaat gtaaaatagg agatttgtgg gaagatgatt atgttttaga tgattctgct
    70801 atagtttgta aaactgataa aggtattttt attgttacag gatgttctca tagtggaatt
    70861 tgtaatatag tagagtatgc taaaaaggta tgtggagatg atagagttat tggtatacta
    70921 ggtggttttc atctttttga attgaataat aggttagata gtacaataca atatttggat
    70981 aaagaagaaa tgagaatgtt gtacccttgt cactgtgttt cttttaaggt aaaagcgaag
    71041 atgaatgaaa tattgaatat aaatgaagtt ggagtagggc tgaccataag tatatagtat
    71101 ttgaaagtat ataagattta agttgaaggt taaaaagata ttttctatag aaaatatctt
    71161 ttttgttacg tttattttaa gagaaatcaa tatactttta tatgaaatat tgtaaaaaaa
    71221 tttattttta atgagaatat attttcatta ataaacaatt ttattatgta ttaataatgt
    71281 tagaataaat ataaataaat caaagttact tacattacag tatatttttt cacaaaatat
    71341 attgatttat tcttttaaag tttgataatt ccaatgaatg taataaaaga a
//
LOCUS       DAMJWC010000011        67571 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMJWC010000011 DAMJWC010000000
VERSION     DAMJWC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67571
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.011"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(403..1125)
                     /locus_tag="PC503_000909"
     CDS             complement(403..1125)
                     /locus_tag="PC503_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2526923.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1184..1861)
                     /locus_tag="PC503_000910"
     CDS             complement(1184..1861)
                     /locus_tag="PC503_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2526924.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1889..2704)
                     /locus_tag="PC503_000911"
     CDS             complement(1889..2704)
                     /locus_tag="PC503_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2526925.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2930..3140)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3858..5924)
                     /locus_tag="PC503_000912"
     CDS             complement(3858..5924)
                     /locus_tag="PC503_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2526926.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(6001..9030)
                     /locus_tag="PC503_000913"
     CDS             complement(6001..9030)
                     /locus_tag="PC503_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2526927.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(9083..10543)
                     /locus_tag="PC503_000914"
     CDS             complement(9083..10543)
                     /locus_tag="PC503_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2526928.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10635..11009)
                     /locus_tag="PC503_000915"
     CDS             complement(10635..11009)
                     /locus_tag="PC503_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526929.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(11185..11925)
                     /locus_tag="PC503_000916"
     CDS             complement(11185..11925)
                     /locus_tag="PC503_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2526930.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11946..12734)
                     /locus_tag="PC503_000917"
     CDS             complement(11946..12734)
                     /locus_tag="PC503_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF2526931.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12822..12912)
                     /locus_tag="PC503_000918"
     tRNA            complement(12822..12912)
                     /locus_tag="PC503_000918"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12876..12878),aa:Ser,seq:gct)
     gene            13171..13935
                     /locus_tag="PC503_000919"
     CDS             13171..13935
                     /locus_tag="PC503_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2526932.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(14216..15331)
                     /locus_tag="PC503_000920"
     CDS             complement(14216..15331)
                     /locus_tag="PC503_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2526933.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15372..16898)
                     /gene="glpK"
                     /locus_tag="PC503_000921"
     CDS             complement(15372..16898)
                     /gene="glpK"
                     /locus_tag="PC503_000921"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2526934.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            17191..18288
                     /locus_tag="PC503_000922"
     CDS             17191..18288
                     /locus_tag="PC503_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2526935.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRY
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(18779..19291)
                     /locus_tag="PC503_000923"
     CDS             complement(18779..19291)
                     /locus_tag="PC503_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526936.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19844..20725
                     /locus_tag="PC503_000924"
     CDS             19844..20725
                     /locus_tag="PC503_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF2526937.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKSVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(21038..21817)
                     /gene="hisJ"
                     /locus_tag="PC503_000925"
     CDS             complement(21038..21817)
                     /gene="hisJ"
                     /locus_tag="PC503_000925"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF2526938.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22363..22713)
                     /locus_tag="PC503_000926"
     CDS             complement(22363..22713)
                     /locus_tag="PC503_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF2526939.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22729..23145)
                     /locus_tag="PC503_000927"
     CDS             complement(22729..23145)
                     /locus_tag="PC503_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF2526940.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23164..23355)
                     /locus_tag="PC503_000928"
     CDS             complement(23164..23355)
                     /locus_tag="PC503_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF2526941.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23506..24321)
                     /locus_tag="PC503_000929"
     CDS             complement(23506..24321)
                     /locus_tag="PC503_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF2526942.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVKGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24368..25306)
                     /locus_tag="PC503_000930"
     CDS             complement(24368..25306)
                     /locus_tag="PC503_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2526943.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25303..26175)
                     /locus_tag="PC503_000931"
     CDS             complement(25303..26175)
                     /locus_tag="PC503_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2526944.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26200..28128)
                     /locus_tag="PC503_000932"
     CDS             complement(26200..28128)
                     /locus_tag="PC503_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF2526945.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28240..28617)
                     /gene="gcvH"
                     /locus_tag="PC503_000933"
     CDS             complement(28240..28617)
                     /gene="gcvH"
                     /locus_tag="PC503_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF2526946.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28704..30830)
                     /gene="cdhC"
                     /locus_tag="PC503_000934"
     CDS             complement(28704..30830)
                     /gene="cdhC"
                     /locus_tag="PC503_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF2526947.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(30887..31693)
                     /locus_tag="PC503_000935"
     CDS             complement(30887..31693)
                     /locus_tag="PC503_000935"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2526948.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31743..33110)
                     /locus_tag="PC503_000936"
     CDS             complement(31743..33110)
                     /locus_tag="PC503_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF2526949.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33141..34085)
                     /locus_tag="PC503_000937"
     CDS             complement(33141..34085)
                     /locus_tag="PC503_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF2526950.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34105..34875)
                     /locus_tag="PC503_000938"
     CDS             complement(34105..34875)
                     /locus_tag="PC503_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2526951.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(34931..36316)
                     /gene="lpdA"
                     /locus_tag="PC503_000939"
     CDS             complement(34931..36316)
                     /gene="lpdA"
                     /locus_tag="PC503_000939"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2526952.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTIKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36360..37241)
                     /locus_tag="PC503_000940"
     CDS             complement(36360..37241)
                     /locus_tag="PC503_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF2526953.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37276..37950)
                     /locus_tag="PC503_000941"
     CDS             complement(37276..37950)
                     /locus_tag="PC503_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF2526954.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(37987..38859)
                     /locus_tag="PC503_000942"
     CDS             complement(37987..38859)
                     /locus_tag="PC503_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF2526955.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(38951..39583)
                     /locus_tag="PC503_000943"
     CDS             complement(38951..39583)
                     /locus_tag="PC503_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF2526956.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39688..41364)
                     /locus_tag="PC503_000944"
     CDS             complement(39688..41364)
                     /locus_tag="PC503_000944"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF2526957.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41613..42392)
                     /locus_tag="PC503_000945"
     CDS             complement(41613..42392)
                     /locus_tag="PC503_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2526958.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42702..44621)
                     /gene="cooS"
                     /locus_tag="PC503_000946"
     CDS             complement(42702..44621)
                     /gene="cooS"
                     /locus_tag="PC503_000946"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2526959.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(45228..46139)
                     /locus_tag="PC503_000947"
     CDS             complement(45228..46139)
                     /locus_tag="PC503_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2526960.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46255..46833)
                     /locus_tag="PC503_000948"
     CDS             complement(46255..46833)
                     /locus_tag="PC503_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2526961.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            47059..47982
                     /locus_tag="PC503_000949"
     CDS             47059..47982
                     /locus_tag="PC503_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2526962.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(48154..49296)
                     /locus_tag="PC503_000950"
     CDS             complement(48154..49296)
                     /locus_tag="PC503_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2526963.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELRINK"
     gene            complement(49314..51068)
                     /locus_tag="PC503_000951"
     CDS             complement(49314..51068)
                     /locus_tag="PC503_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF2526964.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            51204..51410
                     /locus_tag="PC503_000952"
     CDS             51204..51410
                     /locus_tag="PC503_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526965.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51415..52338)
                     /locus_tag="PC503_000953"
     CDS             complement(51415..52338)
                     /locus_tag="PC503_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526966.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52592..54292)
                     /locus_tag="PC503_000954"
     CDS             complement(52592..54292)
                     /locus_tag="PC503_000954"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF2526967.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(54754..55167)
                     /locus_tag="PC503_000955"
     CDS             complement(54754..55167)
                     /locus_tag="PC503_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2526968.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(55235..57613)
                     /locus_tag="PC503_000956"
     CDS             complement(55235..57613)
                     /locus_tag="PC503_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2526969.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            57932..59383
                     /locus_tag="PC503_000957"
     CDS             57932..59383
                     /locus_tag="PC503_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF2526970.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59587..62100)
                     /locus_tag="PC503_000958"
     CDS             complement(59587..62100)
                     /locus_tag="PC503_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2526971.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(62323..63144)
                     /locus_tag="PC503_000959"
     CDS             complement(62323..63144)
                     /locus_tag="PC503_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2526972.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63662..64138)
                     /locus_tag="PC503_000960"
     CDS             complement(63662..64138)
                     /locus_tag="PC503_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF2526973.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(64172..64750)
                     /locus_tag="PC503_000961"
     CDS             complement(64172..64750)
                     /locus_tag="PC503_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2526974.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(64854..67436)
                     /locus_tag="PC503_000962"
     CDS             complement(64854..67436)
                     /locus_tag="PC503_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2526975.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSSISMDLYTSSSLGIPKELMGSNTNNIYTLSNTSKIDTLNKNHSNTA
                     VTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNIDCYLNA
                     FNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVTEYCPMG
                     VVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLDNLYELE
                     EIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKRATDLYKKLDEIGTVAGHYY
                     KGVE"
BASE COUNT        21014 a        12639 c         7422 g        26496 t
ORIGIN      
        1 atatattata ttatacatat acttattttt actataaaag ttaaatttat aagcttactt
       61 gttataaaaa taacttttat aatttatttc aaaaaaaata ttgatttttg tgtcgcattt
      121 tgttataata aattaaggtt atccccctgg taaccctagt tagttaatat atctattccc
      181 aatacccttt cataaggata tattttatat ttattaaaaa tcggattagt aacggaaatt
      241 aattcggtgg aaaaaaagag cttaccccga gctctttttt ttctgcaaaa aatcgtaaaa
      301 ataaagttaa tattaatata actttaattt taaaattaat attaaccatc actaaaaaag
      361 gatgtattga atttctaata tcaataacat cctttttata tattatagca cttttgctaa
      421 aaatgctttt gttctttcat gttttggatt tccgaaaact tcttctggag tattatcttc
      481 aagtatactt cctccatcta taaaaataac tctatctgca acttccttag caaatcccat
      541 ctcatgagtt acaattgcca ttgtcatacc ttctttagca agttctttta taacatccaa
      601 aacttcgttt accatttctg ggtcaagagc agatgttggc tcatcaaaca acatcatatc
      661 tggttccata gcaagtgctc tagctattgc tattctttgc ttttgtcctc cagataattg
      721 tgatggatat gaatcttttt tatctaaaag accaactcta ctcaacaaaa tttctgcttt
      781 tttttctgct tcttccttag tcatcttttt taatttaatt ggtgctaatg ttatattatc
      841 taaaatagtc ttatgtggga ataaattaaa gttctgaaac accataccta tattttgtct
      901 aacctcatca atattagttt ttttatcgac caaatttttt ccttcaaata ttatttctcc
      961 acctgtaggt atttctagta aattcataca tctaagaagt gtacttttac cagaaccact
     1021 tggacctact ataaccatta tttcgccttt agcgatttct aagtctatat tttttaatac
     1081 atttaaatct ccaaaagatt tacttaaatt ttttattgta atcatattat cactttcctt
     1141 tttactattc tatgttttcc ctaaatgcta aacatgctct catctagtta gacacagata
     1201 gtttcttttc taataatcca actaatcttg atagagtaaa tgttataaca aagtaaattg
     1261 ctgctgctac tattaatggc tctaatgctc taaatgctgc attttttact atatcagcag
     1321 tacgcattat ctcaacaact cctattacag atattattga agattctttt acaagtgtaa
     1381 taaactcatt tgctaatgaa ggtaatatat tttttatagc ttgaggtatt attatatatc
     1441 tcatagttga ccaataattt aatcctaatg atctacttgc ttccatttgt ccattatcaa
     1501 ctgattgtat acctgatcta agtatctctg ccacgtatgc accagagttt actgataatg
     1561 caaatgcact agctataaat tcacttggta taccaaacaa catagggaat cttattccta
     1621 attgaggtaa accaaaccat actatatata tctgtactaa taatggtgtc cctcttaaaa
     1681 cctcaatata gattgatgat attgctctta ataccttgct ctttgatatt tttgccatac
     1741 agataattat acctattata aatccaaagc ataatgccac aagagaaatt gatactgtca
     1801 cacctgttcc ttccaaaaaa gaagtcccaa atctacttaa aaaactaaaa tctaaactca
     1861 taatttcatc tcccacataa ctttcttact aatttgaagc agcttcagta gatgcttcat
     1921 ttaaaaattc ttctatcttc ttgccatctt gtaattcttt tatctttttg tttaataatt
     1981 ctataaaatc tttgttattg tcagattttt tgattgctgc tgccatacct tctgttacat
     2041 ctttcccaac ttcagtattt gccattttta ttccatcata ttttttaaca tttattaaag
     2101 aaactgcttc attagtaaca actgcatcta tgtttccatt ttttaattct gtaattaaat
     2161 caggtattgc tttcaaagat tttgtagttg tcatttttaa agtgttaact acatattctt
     2221 cttggatact tcctgcttga actccaactc taagtttctt taaatcatct tcagttttta
     2281 ctttgtctat atctgcatct ttaactataa ctgcatttct acttaaataa tataattctg
     2341 aaaaatcaac actcttttct ctctctggtg ttggagacat acctgcaaga acaatatcaa
     2401 cttggtctgc atttaaagca cctattaatc catcaaatga catatcctta atttcaacct
     2461 ttacaccaag ctcttttgca aattcttcag ccaacattat atcgaatcct tttattgaat
     2521 cttttccatc tactacctta tgaaattcaa atggaggaaa ttctgcacta gtaccaacaa
     2581 ctaattttcc attgtctttt atttgttcta actttgtttt ttctcctcca ccactacatc
     2641 ctactagcga taatgtcaat cctaatacta atcctaaact taataatttt ttaaatactt
     2701 tcattttaac tacccctctc ttttaattat aatttccctc agattttaat acttaaatgt
     2761 ttcgagttac aaaaaaagtc tctcagtctt taatgactaa gagacgactt taccgcgtta
     2821 ccactcttat tgataaatac ttatattact ttcaaaattt gtgactgtta gcatttaagc
     2881 tgtatggata cttttatttt taaatcaaaa aagtccctta gctttacagc taagagacga
     2941 attatatccg cgttaccact ctttttgata agtaagtact tatcctctca atcccttaag
     3001 gcgggtaaac caattatcat actaaagttt ctgataatct cctccagagc tctcttcaca
     3061 tagacttcat tgctaggctt acaccaaccc ctaactcgct gtaaatccat atatgctact
     3121 ttctctatca ttggatttgt ttccttaaat tgttaataca attgtacttc cttataatat
     3181 ttttgtcaat aagtttttta tttttttaat aatttttact tgtaaattat ctaaatacta
     3241 ctgtttatat ttattgatat tagttttgta attataaata gtatatttca tatttttaga
     3301 tatttcttaa ataatactaa ataatatctt tcacattgtt gctttttctt aaacaatact
     3361 aaataatatc tttcacattg ttgcttttct taaattacac taaataatat ctttcacact
     3421 gttgcttttt ctttaataat actaaatagt atctttcaca ctgttgccct ttctttaata
     3481 atactaaata atatctttca cattgttgct ttttcttaaa ttacactaaa taatatcttt
     3541 cacactgttg ctttttcttt aataatacta aatagtatct ttcacactgt ttctctttct
     3601 ttaataatac taaataatat ctttcacatt gttgcttttt cttaaattac actaaataat
     3661 atctttcaca ttgttgcttt tctttaataa tactaaataa tattttccac attgttgctt
     3721 tttctaaaca actataaata atatattaaa cccttatttc tttttctaat aagttaaata
     3781 atacatttta cacatatcta tttgtcttgc acataataaa taatacatta tatttctatc
     3841 taaatttaga ttctaaatta aatagtataa attatattct tcaataaaca agttttcaaa
     3901 tccaagattc gctctctatc tttaaacttt attgtaaaca taattccatc ttttttaatt
     3961 atttctcctt catgaaattt tttatggtat accttatccc ctacaccaat actgtcaatt
     4021 tcttttttcg ttggagattt tatatcatta ataaataatg atttatcaac tttcttacca
     4081 tacttattta aagtagagct tatacataac ttttcttcag ctcttgtaat agcaacatac
     4141 ataagtcttc tttcttcttc taattgttct tcttttttct cttccttaca aatatcatat
     4201 gatttttcat gaggtattgt tccttcattt acacctataa tataaacatt tctaaattct
     4261 aatccttttg cactatgcat agttgtaaat atgacaccct cagtctgctt attcttgtta
     4321 ttttccgtta actcagtctt tactctatca atatgctcta aaaactctgt aacagtatta
     4381 aaattagttg ctgaactctc aagttcattt aatatctcta caagtccatt agtctttatc
     4441 tttctgttgc tacaataatc taaaacatat ctatcataat caagactagt tctaatataa
     4501 gatattgcat ttttaggatt taaagtattt aaataactta aatctatttc caaatcattt
     4561 attgttttaa cttgtttagg atgaagatta cacttattta ttaatgctgt tataaagtct
     4621 ttttcatcct taaccatatt tatactgtct ttggatatat atctaaaagg cttgtttata
     4681 attctcaacc aatctttatt tgattttgga ttaataccta ttcttaaata ggctagtatg
     4741 tcttgacttg cccaatggtc atatattgta attactgagt cttttactac aaatggaatc
     4801 ctcatatcca taaatacatc tactaatgct cttgactgta tattagttct ataaattact
     4861 gcaaaatctg aatactctac ataatctttt tgtatttcgt caattatttc cctggcaata
     4921 tataaggctt cttcctctga atcatgcgga gaaatatagg taacacttcc tccatccccc
     4981 tgactacact taatgatttt ttcatatcta tttttatttt tgtcgataag tctatttgca
     5041 gtatgaacta tctcactttt agacctgtaa tttatatcta atattatttt tttagtatta
     5101 ttaaagtatt gttcaaattc aagcaaaaaa tctggtctag cacctctaaa tccatatata
     5161 ctttggtctt catctccaac tgcaaatata ttgtttaatg ggctacaaat taactttaaa
     5221 acttcaaact gtactttatt tatatcttga aattcatcta tcaatatata tttatacaca
     5281 tttctaacca tttctagtgc agacttattg ttcaaaagta aataataagt tcttataagc
     5341 atatcatcaa aatctatttt attaacttta gatttttgtt cttcgtataa gttgtatact
     5401 tttaaaaact catcttttgt taatacttct gaattaaatt catttttatc cataagttca
     5461 ttttttacat aggaaatttc atttataact tgtcctatat tctcatcatc atcagcattc
     5521 tctatattta aactttttag gattgccttg attgtcattc gctttgactt ttcatcaaat
     5581 atactgtcta agttgtatct ttcaaagtat cttagaattt taaaaaatac agagtgaaaa
     5641 gtaccatagg ttaccttatt aagtcttatg tcatcactta aattcaaagc tctatttttc
     5701 atttctattg aagatgcctt ggtaaaactt attgccaaga ttcttgttgg tgctatgttt
     5761 ttgtttacaa ccatattggc tattctatat gtaattactc tggtcttacc tgaaccaggc
     5821 cctgcaagta tcatgcaagg cccatctata tgctcaactg cttctaattg attttcattt
     5881 aactttctta tatctatatt tgttgtgatt attagctcca ccaccttgat ttataattat
     5941 attattttct ttttaattat aaactaaaag ttcataaaaa taaatttaat ttttcctcta
     6001 ttaaaccaca tcattcctat tttcatgaca tatcttgagt tcttttttaa ttttgtcgct
     6061 tatatcttca ggtataaatg atggtttact aatatagtag ccttgcatat aatctactcc
     6121 aagattaatt agtgtttcca tttcaccttt tgtttctaca ccttctgcta tcactttaat
     6181 atttctttcg ttagaatatg agataagatt ttttaatatt ttctgtctgt tttcatcttt
     6241 atcaatacct cttacaatag acatatcaat ctttacatag tctggcatta tatataatag
     6301 tacagcatct ccgttgtaac ctgtcccaaa gtcatctaaa gcaatttcta tattccaatg
     6361 gtctatatat gctttctttt tctcaataaa atcttcatta atcttatcat tctctgttat
     6421 ttctagtact actctattta aatattcacc atataaatct tcaatttcct caaaatctac
     6481 ttttgacaaa ttattattag gaatagaatt taagaacagt ttgcaatcgc caaatttttc
     6541 tttgtatttt ttaaatgatt taagtgcttt aaaccatgta atacgctcaa tttgatataa
     6601 tttagactgt gaacgagcta atctaatgac atctattggc gaactaaaag tttttatttt
     6661 aggtctcata agtgcttcat atgcaaaaac tttaccttta caatctacaa taggctgaaa
     6721 tgcatactca actaattgac catcaattaa cttgtttaat tcttctctat tactcaataa
     6781 gaatgaatcc ttattatata tattaatatc aaattcacta acttcaccct tgattgtatt
     6841 tttaatttga tacatagcaa aatctgcgta tctcattaat tcatcatagt tggttgagtc
     6901 atcagggtac caggaaattc ctgctgatgc ccttatttta aattctgttc catcatgaag
     6961 ttttaataag gtattattca tctgtttctt aacagaatta ataatatctc ttatactatc
     7021 tttactttca tatccatata taaatacata aaactcatca cctgaaagtc tagatactat
     7081 accattccat gatataaact tcttaagtat gtctgcagca cacctaatat attcatcacc
     7141 agcatcatgt ccatatgtat cattaatata ttttagatta tctaaatccc acataataaa
     7201 tgctgctatc ttaagttcat ctttattctt aaatttttct tgtatctgtg aatgaaaagc
     7261 tctcctattt aaaagattcg ttaaaatatc aaaatctctt tcatattcta tcttcctttt
     7321 ctcaataaat tcttttgtta catcaacaac aacaccaaga acctttagct catcttcaaa
     7381 gatattcatt cttatccact taagtttttt atctttagat tcaaacttat atatatatgt
     7441 attttctgtt tcataacttt cttgcaaata tttatctagt ccccttaatt ttttcaggaa
     7501 cttatttttt tccatatatc catattcttc aaatttgatt tcagtagtaa acacgctaaa
     7561 aaattctttt gtacaaaaaa cattctctgc gtttttgtat aactcaaaag ctccaattgg
     7621 catatctacc atttcaataa tctgtgataa ttttgacgaa gaatctgcaa catttgcact
     7681 gagcaactct atagctgaag ataattcatc tatttcagat atatttatct tatcaagatt
     7741 tactggtttt gatggattac tgtttctaac tttgttggct aaaagaacaa ttggttttgt
     7801 aaataatctt gatgcaatat aaatacctat tagacctatt aataaagaaa ttgctataga
     7861 tattataact aatttctcta ccctttttga aaatgacaaa agactttttt cttcaataat
     7921 acccaaaaga gcccaacgtt cattttcaaa tggagtattg gagttatata aatctaagta
     7981 ttgtacacta gcataaatgt tgccattacc acattcatta tctttatttt taatcttata
     8041 tatattttta tacgattcct tctgctctaa attagaatgt aaaccatccc aaaatttttc
     8101 ttttaatgag tatccatttg aaattacatt ttcaaaggcc atatcattat ttctatctac
     8161 acctaaaata taattaccct ttttattccc atttatctct gagtatggaa gtaattctct
     8221 taaataattt acacttaaat ctattccaag tactccatat acagttccat cttcataaat
     8281 aaggggaact gtatatgtca taagcctatc acctgcattt gtcaataaaa acttacttcc
     8341 ccagtatcct aaattagaac ttgatacatt tggattatca attgcagctc taaatggttt
     8401 ataaaaaaaa tcatctccat cttgctcatt ttcactttta aatgaaaact taggttccca
     8461 ataactgtcc atagatattc caaaacttct tgctatatct gatgaacctc tctcaattaa
     8521 caaatcagaa ttatcatttg gattaaactt agggtctaaa tcccttatat acaatcctgt
     8581 cctacttatt tcacctttac tatctattga cttatcgtta atatttttgt cacttaggat
     8641 tataaaagct cctgtaacag aattttttct caaaagatat attaaatcat ttgatatgct
     8701 ttttataata tctttgttaa tttcttcatt gttgcctaca tcctcaatta aggcattttt
     8761 ttcatttaat acttttttta cagaggaatt aattgtagct tccgtttcac ttgtatttga
     8821 ccatctttgt aacatttcat tttgtatata atttttacga ttaattactc tttcatttaa
     8881 gatgtcaaac gaattatcat ttaatttctt aatagttcct ccccataaaa ttgtggcaca
     8941 aaataaactt gtttgaatta gcataacaat aattagggga aatatcatct ttttcattat
     9001 tgaattgttt tttcttagat tgttttccat acccattcca cctatacctt tgtgctcgtc
     9061 aacacactaa ctgccaattc atctattttt ttatagcatt ttcaagctca gccttaaaac
     9121 tttcaaacca agttttaaaa tttttatcat tattaaattg tgctactgca tccttcttag
     9181 aagttccact ttttactaat tcatttattt tatttgaatc ttctttagct ttatcaagca
     9241 ttgaatattc aagtatttgt ctagctttag ttccaccatc aaatgcttta ttagtatata
     9301 aattacaact gttaatctgt tcaatagatg aggctattga accttcaact ttatcagaca
     9361 aactcaaatt atctttcttc ataacttctt ttataacatc caaatcattc gtttttttct
     9421 ttactggtaa gtatccagaa gcaatagaga attttatatt aggttcttta tctgtaaacc
     9481 attttaaaaa ttctactgat gcatattctt cttctttagt agattttgtt acagccattc
     9541 ctgcaccttg ttgtacagca tattttcctt ctcctttaaa acgtggtgct tgaaaaacag
     9601 atgtttcaat attataactc tcattatcat ttagcattac tctatctgga aagtatgctg
     9661 ctcctgaact agaacctaca agagctaata tatcacctgt ttttgcatca tcagaacgaa
     9721 acttaccata agaagcaaaa tatccattta tatatggtac atagaaatta tcccatagtt
     9781 ttttcataac tttttcatca atatttagcg taactttacc atctttaaca gaaaaaattt
     9841 ctactcctag ttgtttactt cctataataa tataatttgc taaagcatct cttccaaaaa
     9901 atgctttacc atcattaggc tctttcgtta aactatctgt ccattcataa tatttttttg
     9961 atgtctctac taatccttca attgttttta tatcatttat atttgaattt gtagcttttg
    10021 caaatttatc ccaatcagtt ttatttaaca tcaaaatttc agttgatttt gcaattggga
    10081 aaagtttaaa ctcatcctta gaatttattc tgccttcttc tacatattcg tctatgtatt
    10141 catttaattc ttctttactt atgtacttat ccatatctac tagtaaccct aatttatcca
    10201 tttcatatgc agtatctgag tatgctgcaa atatatttgg tacatcttca gaaccaactt
    10261 ttttatttgc agaatctaaa actttctctg ataaatcaac tacattacct tgactgaatg
    10321 cttcaacaat aattcctttt tcagcaccta cagtgtcatt aaattcctta acaagcttat
    10381 caaaagccat tttctgctgt ccattataat aatgccaaat ttgtattgat gtcggatttt
    10441 ctgggtctaa cttataatta tcttccttct ttaaactaca tcctgtaagt aataaaacaa
    10501 tcattgatgt gataattaat tttgcaaact tacacctatt cataaaatct actccttcaa
    10561 attataaaat ttataatagc attaaaactg taacttcact atttatatta attatagaac
    10621 gtttattgat atatttaaac aggatttaca acatatttaa aagcaattaa gaaacatact
    10681 attacaaata tagaaaataa agcttttaca taatttttat ttctaaatgc accaaatgac
    10741 accaatcctt gttgaatagc tactgtaatt actaaaagta tcattattat attaagttga
    10801 accagtttaa ataagtaaag caatgaaaac actactagaa gtacacataa tacaatacta
    10861 gatttattaa taatatcatc aatcttatct actttcttag attgcttatt aattttattt
    10921 aatttttctt tatttaaatt ctcaactttt ttattatacc tttctcttgt tttatcttta
    10981 tatttagtat ttttattttt atttcccatt tattttccat cctctataaa ttttttaatt
    11041 gagcttatac attatttaaa tattatatat ttaagatacc atatattcct acaaaaaggt
    11101 aacttactat gtatctattt ttgattttcg cataaaaaag ccatctcctt tagaattaat
    11161 tctgtattga gacagctaat ttaactattt atcctttgaa acattttcta cattatcata
    11221 tttactatca actaaaacta tatcaactct tctatttttt gacctacctt cttcagatga
    11281 attttctgct attggtctaa actcaccata tcctacagca gataatttat ctggtgctat
    11341 acctgcattg tcaataagaa gttgaacaac attggttgct ctcataactg ataaatccca
    11401 atttgactta aactctgaat tttttataga catattgtct gtatggcctt ctactctcat
    11461 gtaactattc atttcattta acatcttacc tatttgaata atcttatctc tagaattatc
    11521 cttcacaata gctttccctg tatcaaatag tattgtatct ttaaggctta ttactaatcc
    11581 tctatcttga actcttaatg atactgaatt agccatacca ttttcgttta aatacttctg
    11641 aatttcttca ccaatttttt taaacttagc attttgtaaa gtatctaaat cattacttcc
    11701 tggttcaact actggttcta tcttgctatt accaccttca ataactccag aagaaccacc
    11761 aaaagcagaa tttagagatt gagataattg tttatatttc tccgcatcaa cattactcat
    11821 agaatacatt attacaaaga aaatcataag taatgttatg aggtctgaat aagttaaaag
    11881 ccatcgctca ttgttttctt ctttttcatc ttcatcatac aacataaaca ttccatcctt
    11941 ttatattatt cagctctacc accaatttct tcaagttcaa ttagttcttt tgaatttaaa
    12001 aatattttta atttttctgt cattaaatta gaattatcac cctcaagtat ggataatatt
    12061 gcttctatca ccaaaagtct ttcacttact tcttgttgat ttatagcctt aagttttgat
    12121 gctattggta accatattaa attggcagaa ccaacaccat acaaagtagc caagaatgca
    12181 acagaaattt gaggtcctaa tgcatctgga ttacttgaaa gattacctaa aatatgtact
    12241 aatcccataa ctgtacctat tatccccagt gtaggtgcat atccacctgc tgaatcaaaa
    12301 attgctattc cttctttatg tcgttttgat gttatctgta tctgtgattc caatatattt
    12361 cttatagtaa ctgcatccac tccatctacc ataagttcaa gcccttttct aataaaaggg
    12421 tctaattcat cattctcact tatttctttg tcaatactaa gaagcccctc tttcctagcc
    12481 tttgttgcaa tttctttgaa atagattata ttttctatgt tattaggctt tttattttta
    12541 aaagctaata acattatctt tatagacttt ttaaacacag ggaatggagt cgaagctcca
    12601 acagctccta tagttccacc aaacacaaca agtgctgatg aaaatacaaa taatgctcca
    12661 acatgtcccc catcaataac aaaagcaact accaaagatg ctatccccac tatgaaaaaa
    12721 attaaagttg tcatctattc cctcctttct ttagttatac atatctaatc atttatgaca
    12781 ttataaaaag actatcttta ataaaaatag cctttaataa ttggcggaga aggagggatt
    12841 cgaaccctcg caccggttac ccagcctaat cccttagcag gggatcctct tgagccactt
    12901 gagtacttct ccatatctct atactaataa attatataat aaaatcatat tttagtcaat
    12961 tgttttataa aatttgagtt attttgaatt attaaacatc tatttttact tttttgctta
    13021 aatgtaagtt ttaaatatgg taaaattatc ttgcataaca cttataatat tatttgataa
    13081 atatacatac attaacaaat atacctaaac tctgacttaa ttgtaagtta tgccaaaact
    13141 aaaataatac tagtccaagg aggatatttt atgttaccac aggaaagata tgagaagatt
    13201 ttaagtattc tcaaatcaga taatataatt aaaataaatg acatagttca aatgtttgat
    13261 atatcaatag aaactgcacg aagagattta gcccatatgg agagtatcgg tcttttaaaa
    13321 agagtttatg gtggtgctat accagttata gcaagtagcg tagaacttaa ctatgttaaa
    13381 agaaaaaaaa taaactcaaa cgataaaaaa cagattgcta ttaaatgtag tgagtttata
    13441 aatacaaatg atactatttt tatggatact ggaactactg tacttgaagt ttcaaaaaat
    13501 ttgaaagata aaaagaatct aactgtaata accaactcaa ttttagttgc aaacgaactt
    13561 atgaatacta atataaaagt atatgtgctt gggggctatc ttagagaaac tgaaggttct
    13621 ttttctggtc cgcttacact gtcagctatt gaacaattta atgttgataa agctatttta
    13681 ggcgctggag gtatcactct tgaaaatgga atctctgact atcacttaga agaagcactt
    13741 gttagaaaaa aaatgattga aaggtctaga aaatctatag tagttgtcga acctcctaag
    13801 tttggtataa attcatttgc atcagtagct cctatagaac atatagatac tattattacc
    13861 tctgctagta tagaccataa tataataata gagttttctc aaaaaggaat acctttagtc
    13921 atagctgata attagcttat atgattgatt tttagttcct tgatgtaata aattaaaatt
    13981 aaggagccaa ataattattt atttagctcc atttatgtct aaactatact ttatatttta
    14041 attatgtaac tactttcagt tagcttatca tttttagtta tttgattgcc attttattta
    14101 atttataagt tttagttatt cgattatttt ttaattgtct gtctttttaa tttattttta
    14161 gttatttaaa ctcctacttt aaaataattt aaatttgact taagtattgt ttattctaca
    14221 ctgcatcttt cttcatttta atactttgtt cttcttccaa ggttaaatct tttgtcataa
    14281 gtatagcaag tgcaattgcc aatactcctc caaccaattt tccaattaca acaggtgtaa
    14341 tcatctctgg aactactcct gctgtaaatc ctaaatggtc ccccaaagct gctgtagcac
    14401 aaaccagcca agcagtattt actactttcc cctttggact catatctttc atcattttat
    14461 atactggaat actattggct aaagtaaaaa ctaatcctgc tgcactagtg gcatccatac
    14521 ctaattttcc acccactatt gtaagtggtt tattaagaac tttaactaat aaatgtaata
    14581 ttggaaaagt acctaataac acgattgcaa tacttccaat tacttgaata ccttctctta
    14641 taggtgtcat gccttttata agtactatac ctgttatttc ttgaaatgct gctgctccca
    14701 aacctatcgt tatcaatata gatataaatt ttccaaaaat taatgaccca tttatcataa
    14761 gagtagaatt aaattttaaa cctactgcca atattactgc caatattatc actggtatca
    14821 tatttataat taccattgat aagttaaatc ctgctattaa tcctcctata atacctccaa
    14881 agggtattgt tatcaagcct atcagtaacc cttttgcaaa gaatggtctg tcttcatatt
    14941 ctataagacc tagtcctact ggaattgaaa atactaatgt acatccaagc atggatgaca
    15001 caaccaatcc tgcaagcatt cctgcctctt tattgtgtgc aagttccata gccaatggat
    15061 accctcccat atcattcgct aaaatagttg caaacataga tgggtcagct ccacagagat
    15121 tgaagattgg tattattata ggacctagta catctgaaat tactggagct aaacaaacta
    15181 taccaaccat tcctaaagcc aatggaccca ttgaattaaa cccttcttca aactgctcgc
    15241 caagtccaaa tttatttcca attattctat ctaacgctcc taaaagcact cccacagcca
    15301 ttatgtataa tataatttta tcaaagggca tttttaattc ctcctataca tgtaaaatac
    15361 tctattgtaa cttaattagc acacaccttt ttggtatcgt tttcccaatt catagctctt
    15421 tttactgctt ggttccatcc aagtaatatt tcttctcttt tttgagtagt catatttgga
    15481 atatattttt tgcttattgt aaattcactt ctaatttcat caatactgtt ccagacacca
    15541 caagaaagac ctgccatata tcctactcca agtactgtcg tctcaggatt ttctgcaatt
    15601 tcaattggta tacctaatat gtcggattga aattgcattg taaagttatt tttagtaatt
    15661 ccaccatcta ctctcaacat ttttattttt ttccctgagg ctaagttcat agaatcaaca
    15721 acatctttga cttgaagtgc aacagactca agagtcgctc ttactatatg ctctttttta
    15781 gtacttcctg ttatcccaac cattgtacct ctagcatatt ggtcccaata aggtgctgct
    15841 atacctgcaa atgctggtac aaaatataca cctccagtac ttgatatgga atttgccatg
    15901 tcatcagttt ctgaataatt ttttataact ccaatgccat ctctaagcca ttgtattgca
    15961 gcacctgcta tatacactcc accatcataa gcatatgtaa ctttatctcc tattttccaa
    16021 gcaacagttg tcaaaatacc attacctgct atatttagtt cctcacctat attcatatat
    16081 aggaaacatc ctgtaccata agtattttta accattcctg gttcaaaaca tccattgcca
    16141 aataaagctg ctggttggtc taccattgaa gcagtaattt ttatagaaac cccacaaaat
    16201 gcctccttat ctgtagttcc aaaatcacca ctcgtaggca ttatatctgc taaaatactt
    16261 ctaggtactc ctataatgtc aagcaactct ctatcccaat ccatatctct tatattaaaa
    16321 agcattgttc ttgctgctgt agatacatca gttaaaaaag attttcctcc tgtcattttc
    16381 catattaacc aactatctaa tgttcctgca agtacttctc catttttaat tttttctttt
    16441 acacctttta cattatctat tacccattta atttttgtac ctgagaaata tgggtctata
    16501 attaacccag tcttatctat tatcttattt tctaaacctg gtatattctt taaattttcc
    16561 acataatcat aagttctcct gcactgccac acaatagcat tgtaaagtgg tttacctgta
    16621 tttttatccc ataacattac tgtttcacct tgattatcta taccaattcc ttttatatca
    16681 ctttcattga ttccattttc aaaagcctgt tgtaatacat tattactcac agtttttgta
    16741 ttattccaaa tttctatagg gtcatgttca acatatccag attgtggata tatttgagta
    16801 tgttccatat aatcgctaaa aacaaactct gatttttcgt ttatcaatac tgctcttgtt
    16861 cctgttgttc cttggtcaat tgctaataca tatttcactt taaatgtcct cctttatttt
    16921 cagaattaat aaattctttt ttattttttg aatatataat ctattcaagt tatttatatt
    16981 ttatatcatc atgtggattt atgcaatatt cattacaata ttttttgtta tttttaatta
    17041 tagtgattga aaaagtattt ttattgaaat attgttgcaa tatttattat tttattctat
    17101 aatctagtta aaataacaca taatatttta atatttacac ataatcagtc attcaaaaat
    17161 ttaaatttaa ctttttaagg aggctttaca atgaaaaaaa catatctatt cagtcctgga
    17221 ccagtaatgg ttacagataa agtcagaaat tcacttcttc actatgatat atgccataga
    17281 ggaaatgagt ttatggattt attcaaagat acacaacaaa aaatcaataa actatataat
    17341 gcaacttcta attactactc attaattgta tctggctctg gaacatctgt aaatgaatgt
    17401 gtactatctt ctatctttga caaagaagat gcagttctgc tagttagtaa tggtgttttt
    17461 ggagaaaggc tagaagaaat attatctact tataatgtaa aaacatataa acctaatttt
    17521 gaatgggcag aatacccgga cctagacatt ttagaaaaat acataattga aaactctgat
    17581 ataaaagtaa ttgctatggt gttccatgaa actagttcag gaatgataaa tccagtccct
    17641 gaactaggaa aacttgctaa gaagtataac aaaatatttt ttgtagatgc aataagtgcc
    17701 tcagcaggtg aatatattga tgtggaagag tttaatatag atataataac aggtgttggt
    17761 ggcaaagctc ttggagcatt tccaggttct gcataccttt gtgctaaaga gagtatttta
    17821 caaaatatta aagaaaatca atgtaagaat gtgtatctta atctttataa acactataaa
    17881 gttgctaaat catcttctca aacaccaaat acacctaatg ttactttaat atttgccctt
    17941 aatgaagctt taactgagtt tttggaagat gacagtaaaa tagaaagata caaagaatgt
    18001 tctgctattt taaggtatgg tatggaagaa ttgggtctaa catttttact tccagataag
    18061 tatatgtcta atacagtaac atctgtattt ctacctaaag aaatcaatgt aaatgagttt
    18121 atattagggc tagaaaggga aagtggctat gttgtctatc caggaaaagg caaattccta
    18181 gatgctaaca tattccaagt agcaaatatg ggagaaatat atccagaaga ttgttataaa
    18241 ttcttagata tcttaaaatc aaaattggag ataaaaaaag ttatataaca gtttgtttgt
    18301 aaaatcctac aatatatcag tataaattaa atagactgat ttttttaaat tttcctataa
    18361 taaattatat tttatatttt tgtataaggg tgaactataa tatgtaaagt tcacccctat
    18421 ttcaaatctt tttccttcaa tataatcttt ttcttttaat ttattttata tttttgacgc
    18481 aatcgttttt tattcaatca ttttatattc ttgatacaat cattcttaca cttaattatt
    18541 ttttgttttt gacacaatcg ttttttgttg aatcatttta tattcttgat acaatcattc
    18601 ttacacttaa ttattttttg tttttgacac aatcgttttt tattcagtca tttaatattt
    18661 tcaacacaat cattcttaca ttctattatt gtttgttttt gatacaactg tttttattca
    18721 gtcatttaat attctcaaca caattacctt ttcattcaat caaagtaatc tttaagcatt
    18781 atttttcaag ctcatcaaag taattatata cgataacctc acctgtctct ttatctgtag
    18841 tctttataat gcccttagct ccatttacct cttcttttgt aaattcatca tctaacacaa
    18901 ctttgaattt atcttccttt ccataacctt gttgaaattc atctctcaaa attgcatttt
    18961 tttctgcttt tggcttcaac tcaaattcaa ttccagattt catttcatca aaataattta
    19021 atactacaac ctcattattc attttattag ttgtctttat aatcccttta gctccattta
    19081 cttcttcttt tgtaaattca tcatccaatg ttatattaaa tttgtcttct tttccatatt
    19141 cctcttgaaa atccctcttc atttcattgt atttagtttc aaactcttta ctcttgttta
    19201 attccatagc tgatacattt gtcaatgatg ctccaattgc cattactgtt aatgccatta
    19261 ctataccact tttaaatttt tttactttca tatcttacct cctaaattaa atgttctcaa
    19321 tgaaattata taaagaaaat cctaagtttt acagtttcat tcttgtaact aaaattacta
    19381 ttatgtaacc aaactttttg cttcaactat tccttaaaag ttgctttttt gaggaatagt
    19441 tgaagttaaa taattagatt ttatctatat ttatagattt aaaatcaaat ttatccatat
    19501 aaataaatac ttatttttgc aaaataaaaa tttttaatta ctccaatcct tcttatttac
    19561 ttaaaatcct atgataagaa atttaaaagt ctttaccttc tttaacaata atttatttac
    19621 ttttaacata caaaatatag agagtatatc aaaactattt tactgaatat tctaaaaata
    19681 agtaccccct attagtatat atatttacat attaaaaaaa agttttaaat aaagttatat
    19741 tttttacaac agttttgtaa ttaaaaacat attgaaggta aatttaaagg tactatatac
    19801 tataaatatg tcgacacaat aaatttaaaa aggagaacta aatatgaaaa aaagattaat
    19861 aataatgata ttgtctgttg tcttagtact atcaagtata cttacgatat ttgcatattc
    19921 aaatattaaa tataataata acaaattgat atattctaat atgatagata aaaaaactca
    19981 aaatagtgta aaggaaatcc taaaagaaaa taaaattaat gaaaaagaca tagatacatt
    20041 tattaaatca gtcaacaatt ataataaatt gcaagttaaa atacttcaaa ataatataaa
    20101 tatatctaaa tctggatatt cttcaatcaa tgcaaaacaa gttccatata acctagaaaa
    20161 attgcaagat aattgggtga aaaaattccc tgattatatg gatgtaaatt gtagaataac
    20221 tgcttttaga ctttttaaag attttataaa ttcaaataag aaatttactg gagactctat
    20281 tgatttgaat gtcgacttgg acactataat gaataataaa gatgctaaat ttagcaccaa
    20341 agatgtagaa aaatttatca acttcttttc tgcaatacca gctaaagata cagatgatac
    20401 aatcaaaatt gcagaacaaa taaaaaatga atggaaaaaa agaaaaatat cttttaaaaa
    20461 taataaaaat atatctatta taaatggatt tcttcgttat ccagaaacta aaaatgtatt
    20521 tataggtcat acaggcatat gtattaaaac taaaaatggc attctatttt tagaaaaata
    20581 cggtgttaca tcaccttatc aagttactaa atttaaaaat aaagaagatg taaaaaatta
    20641 tatgtttaat agattgaaga tgtcagaagg tgaaattgaa ttacctgacc ctataataat
    20701 ggaaaacgat aaacttatga aataataact ttaaacgcaa aatagtattt ataattacta
    20761 agtcaatata atagagaagg tctatagatt tgtgtaaata caagcttatc tacaatctta
    20821 tataagaatg tttatataaa taagatagat taattctaag tcctattatt ctattgaatt
    20881 ttattattat tttatttaga ttctattgtt attttactta gaacttatta ttattttgtt
    20941 taagttctat tactattttc aatcatataa atttacaaaa gactgtacat aaatttattt
    21001 tatacaaact tatctacagt cttttgtgtg aatatatcta aataatatcg tatttattta
    21061 tttcctctgc acagtgagaa tcagaaccta aaactaatgg aatatcgtat ttttttacca
    21121 agtctaataa gtatccatct atataaggct ctttgcagta ctcttttcta tttccagaaa
    21181 cattataatc aagttcataa cctttttctt taattaactt tattaactct tcaagaattt
    21241 tatttccttt ataatcgtat ggaaatacct gattaaactt tctaactaaa tttaaatgac
    21301 ctattctttt tggtttatgt atacctaaat ctgaatttac agcttttatc aatgtttcat
    21361 aatacttatt ataaacagct tcaatacttc ctaatttgtc gattaaattt tgaaactcct
    21421 ctacactgta atctacacaa taataatcat catcaatctt aattatatgt actgataaaa
    21481 gagaatcctc taattccttt ccatatttat ttaaattctc ctttatccct tcttcgtatc
    21541 cttctataaa atccacttcc gacccaacat ttatcttgat tttaccctca tacttttctt
    21601 tcaacttctt gacatcatta aaatactttg gtaaatcttc aatactcata caactatcat
    21661 tttcaggagc agggtctcta aatccatttg catacggaaa atgttctgta aatgtcattt
    21721 ctgttattcc aacatccatt gctctttgta catatttttc aaaatcatcc ttacttccat
    21781 gaggacaata aggtgaatgt atatgaccat ctttcataaa taattcactc cttttttaaa
    21841 gaaaaaatct aatataaatg cataaatctt ttaacttcaa aataatattt ttaatcatgc
    21901 taatttttat tatatctaat attagagtaa ttttaaactg ccttttaagt atcttatcat
    21961 tagtactatt ttcaacttaa cattaatatt attttttaac ttaacattaa tactatcttt
    22021 aaatagtaat actcaatata taattactta acataaaata actcaaattg cttgatgagg
    22081 cttttgcagt atttaaagaa tatataatta tttaacatta aataatccaa tcttgtaata
    22141 aaatttactc attaaagtat attacagaaa atacctcaaa ataaactttt tagttcatga
    22201 tatactcttt tttgcatgaa attagatata tttttatcat ttcaacaatg aaagggaggc
    22261 ttatatccat ctttagacaa ccccttagat aaaattttta ataattaaac atcacaaaat
    22321 ataaaaatcg cttatatcaa acgtataagc gattaattat atttacatat gttttttagc
    22381 ctctaacaac attttattag cttcttccat atactctata gccttttcaa tactctttgc
    22441 tgtttcttct tttccaatag ctctagcctt ttcaacccac tctctaaatc cttcttcatg
    22501 agtttcattg tgatttatcc aatgtactaa aagtattttt aaagtttttt catccttaga
    22561 ctctgatgat tcctcatgac tatgttcgtg gtcgtggtcg tgagcatggt catgtggatg
    22621 ttcatgacat atatctccat gagtatgttc gtggcagtgg tcatggtcat gatgtccatg
    22681 atgatatctt acaatctctt tatcaaaaat cattagttat tccccctgtt attttatatt
    22741 aaactctttt tttataaggt ttacagaatc ttttacaagt agtgctaatg gtttaccttc
    22801 taatccaact aactccacat tttctggcat aataggtaaa agtatcttaa gtgcctcact
    22861 gtctgcaata gcttcactta tattacaagt aacttctccc atcatagaat taggtattat
    22921 tacagaaata ggtgcaacta ttatatttgc ttttttagct gatactacta tagcattttc
    22981 ccctgtagct cctttattag catgagcttt catcatagaa ctagttgcta tagaattagt
    23041 ccctagtgca taaatttcta catatgtagg taactcttct ctcaaagaag aaactatctg
    23101 ggctccaata cctccaccca ttccatctat cactgctatt atcatatgaa attcccctat
    23161 taattaattt tcttgtatta ttatcttatg gtccatcaat cttatttctt taattatccc
    23221 atctattatc ttttgctctc ctaataaatc cgttaaataa atctttccat cacaagggtc
    23281 tatattaacc acattttcca taaccttttc taactcatta ttacttttac aaatgaaagc
    23341 tgatgattca cacatataaa tctcctccta atatgatttt tattaaaaat caaaaaaaga
    23401 ttcccttagg tatttcaata caccaaagaa accttcatga tttcagtttt tgtatattat
    23461 tataccttaa gtatatcact ttaatttatg taaagtcaat taaagttaac gctttttatt
    23521 atactcttca ttcttgtatt tttcatatag ttctttaact aattgcttct cataatcagt
    23581 caaatcgccc ttcacaaact caacattaaa ttgttcagct aatcccttta ctatgttttt
    23641 ctgtagaata tctatgtcta tttttctgcc aatttcattt tctattccac ttgctttttt
    23701 agctgtaaat ttcatagctc tttctttcaa ttctggtgtc ttagttttta ttaatttaaa
    23761 caatttttct acatcaaaat ccagtattat tgaaccatgt tgtaataaaa caccatcttt
    23821 tctactttga gcacttccaa ttaccttctt attattaata gtaacttcat atgatgcatg
    23881 tgcattaaaa catgcagctg ataaattttc cctacttatt ctctcgcctc tatttaaatt
    23941 atctgtttct ataccactta gattcaaccc tttaactaga ccttcactta tatatctata
    24001 agataggttg atgctcttat cgattaaagg attatcttct cctataatta tactataggt
    24061 tagctcatta tcatgtaata cagctcttcc acctgtaatt cttctagtat agtctatatt
    24121 catacatcta cacttatcta aatctatctc atcttccaat ttctgaaaat atcctatact
    24181 caaacaagct ggttcccatg tataaaatct aagagttggc ttattatgtc ctttcttata
    24241 tgcagtaaat atagcttcgt caattgccat attcattgct ccttcatatg atttattatg
    24301 tataactctc cactgattca tgattattac gcctccattt ttagtataaa tatatcctag
    24361 aaatcctcta tagatttatt tctcttattg ctaaatctat ctcactttga tttaaaggtc
    24421 ttgaatagtt gtatatagta cttcctggtc tttcattata gtatggtcta ttacaatcct
    24481 tacaacctct tatttcaaaa ggatagcctt tgtttatgtc ttttaaaata tcattgtcaa
    24541 gctttatact atttaagtat ccatttttaa acttaaaata ctcttttgga taacctttat
    24601 ttatcatata agacattaac tgtacccttc tataactttc tatgcttggt tgatttatct
    24661 tttccatttt agttcctcta actggagtaa atgcaaataa actaatcgtt acatcatttt
    24721 cctttaaata agtatataaa ttgtatatat cttcatgact ttcacccata ccaactatta
    24781 tatgtgtact tattttattg ggatatgatt ttgacatttc agttataaat tttaactttt
    24841 catcatagtt atttcctttt attttttcat atagttcttt atttgctgca tctattgcta
    24901 ttcctatttt atcaactcct gctgaaaaaa acttctttat ctgttcatca ttttctaatt
    24961 ttgcagatag tgaaattggc atgtctatct taccacttat atagtttata aagtctaaaa
    25021 cagagttatg tgcttcttca cttgccattg attgaataca tattctcttt atattttttc
    25081 ctttataagc ttttaaagca tctaatattt cttcttttga aaactctggc caaattactc
    25141 ttgataattt atcttttcta gtactacttt ctattgattg agaacaaaaa ctgcatttat
    25201 ttatgcattt ttctccaatc attatatatg ctgtggtagg aggtatatcg ctttttttgt
    25261 ttaatatccc aagttctatt gctgtcccaa ctgatagtct aatcataaaa cgcaacactc
    25321 cttacactca tttattgtca tattcatttc tatagcctta ttctttgcag accttgatgg
    25381 taatactatt ctattgactc cacacattat agataattgg tctagctctt ttctatacac
    25441 tcctcttggt ctcatacaac ctagattaat ttcagtatct ggtaaattaa ttctagcttc
    25501 acataaaata tctgctaccc cttctaactc aggaggttct acattttcat actcagtccc
    25561 ttttgttgga ataaggacta taaatgtaag cttattagga ggattttttt gtaggtattc
    25621 tataatttca tattcaccct ttatttgtcc tccttttaaa ccaatacata tatgtggtgc
    25681 tacttctgta tgttcttgta ttgtattata gacttcaata taatcttctt tactcttttt
    25741 catcttataa acttctctta ttgtctcatc atcaaacact aaatcaaaag aaactatatc
    25801 taaatactta cacaactcta caatgctatc tttatccata agacctaaat gagcattcaa
    25861 tctatatcct tgctctttta agtttttaat ggtattaata tgagtattta tagggacatc
    25921 tccctcataa ctacaaccgc cactcaatag aaagctagtt atattccttg attgtacttt
    25981 ttcctcatat tcttctattg gcaccatatt gtttaagtag tgaccgttgc aatgggcaca
    26041 tttcaaacta cattgattgc ttgtagtact aagagctagt gtctggttag gataagcaaa
    26101 ctctatttta tttccaaaat tctttaattt aatatcaaat gctattttca ttttttcaga
    26161 tagattctta ttcatagttt attccttctt aagtacattt tactcttcta gtaatttctt
    26221 tgctgttggg aactgctcta tattcgtatg tggtaagaaa catgcagaaa taaattcatc
    26281 catataactt ggatatacac taagttcaac ataagttatt tgattaccta tttcttcaag
    26341 tttatttttt gcatctttac ttataagcgc taagtaagaa ccaacaagtg aactattccc
    26401 tatataagta aatttttctc tatcaatatc aggaagtaac cctataatta ttgagttttc
    26461 tatgtctagg ttgtttccta taccacctgc tatataaacc ctatctaata tactaaaatc
    26521 catacctaaa ctatctacaa gagtgtatgc gcctgaatat atagctcctt tagctctgat
    26581 gaaattatct atatcaactt cattgactac tatatcattt tctaaatcaa attcttcttt
    26641 aaatgctaat acatactctc ctatctcatg ctcattaaat ctaactctct tattatctaa
    26701 atccctgtat attttacctc ttctatctat tacaccttta gtaatcattt gacagattaa
    26761 atcaattata ccagaaccac atataccaac tggtgcacat tcatcaataa tctttaatgt
    26821 tggctctaaa gtatctttat caataattac tttctctatt gctcctgctg atgctctcat
    26881 tccacagctt atccctccac cttcaaaagc aggtcctgct gaacatgcac agctcatcat
    26941 ataatcttta tttccaaata caatctctcc attagttcct aaatctataa ataaaacatt
    27001 ttcttcactt gaccatatcc ctgctgataa tacacctgct gttatatctc ctcctacata
    27061 acttgcaaca gatggagcta agtacacata tgcactgtca tttacaaaaa gaccaacatt
    27121 ttcacccata agttttggag attttaaaaa tggtggtatg taaggttctt gtcttaagaa
    27181 gtctgtatac acacccaaga ataaacttgt catagttgta tttccggcag ccactaatgt
    27241 aactacatct tccttatcta ttccatttct ttcatatatt gtttttaata gtggatttat
    27301 agtttcctca actatagctt tatgaagtgt ctctaatcca tttttcttag ttgaatatat
    27361 aattctattt ataacatctg ctccatattt tatctgtgca tttccagaag atgctttatc
    27421 tactacctct tttgagtata ggtctactaa acaaacaact actgaagttg taccaatatc
    27481 tattgcaact ccgtataagg aattttcttt atttccttgt tctatattta tgattgtaag
    27541 tttcttttgt ttttgaacat atgttattgt aaccttaaaa tcactctttc taaatacagt
    27601 tggcattttt ctaagtatat ccaatctaaa atctatttca ttatatccta ggttatttct
    27661 aacatatctt tccaatctat ctacatcact tatattatca tctaaatttg gttcttccat
    27721 ttctatgtat ttctttttta tatttgtttt aaattgaagg ttatgttctt caattatttt
    27781 tttagctctt tcaaaaattt ccctatcctc ttttttatta ctaccttcta tcttcatacc
    27841 atgcatagaa gatgatactt tagaaggaac ttcaatttct atatctgata ttacctttgt
    27901 acaacaagct agtatataac cttgctccca ctcatcatct gttatatgtc ttgttttttc
    27961 tgtatcaact tttccattca ataattttac tttacacttc ccacaagaca cgtttccatt
    28021 acaaggagca tctatgaata tatctgcatt tcttgcaacc tctagtaata tatccccctc
    28081 attacaataa acctctttat tgtttggtgt aaaacttact tttatcatgt tatccctccc
    28141 aatttgttct atatatgata aaaggaaagt atagctaaat ttgcgtgcac tcaaatttta
    28201 ctatactttc cccaattata ataatatctt aatctttaat tattctaatc cagcctcgta
    28261 ttctttatca cttaataacg tatcaagttc agccacatca gctagtttta cttttaatat
    28321 ccagttttca tatgggtctt catttataca ttctggctca tcttctaatt tttcattaac
    28381 ttccaatacc tcaccattaa caggagatat taaatcagaa gctactttag aagactcaac
    28441 tactccaaaa tctactccct tagttacagt atcttctact tctggtgttt caacaaacaa
    28501 tatttctcct aattgatctt gagcatagtc tgttatacct atatatacaa catctccatc
    28561 aattactttt acccactcat gatctttaga gtattttaat tctggtaata atttcatttc
    28621 gatagacccc caatattata ttattgatta aattacttaa atcatattaa tattatatca
    28681 tattatttta aattttccat caattacatt acactttcca tagctaatgc tggatgacct
    28741 ttttcttcta agaaagctaa tactccttca gaatcgtcag ctatagtttc atcacaaacc
    28801 atatcacaga agttttctat tccagtcatt tctttaactg tagcatttaa tttatcagct
    28861 acataatctt ttaattcttt tggcatccaa actattcttt ctggtccacc ttctgcataa
    28921 gcgaattttt tagaagatat aaaatgtctt ccgtgtccca taaatcctgg agtttgaact
    28981 cctccacctg tcatagaagc aagttctccg aaagtcatac caactggagt aacacttgca
    29041 aattctctgt taactacaac aaatccattt gcttctggca ttataccaca gatacattcg
    29101 aagcatccac aagaagtcat tgggtcttct agtatagagt ataatgtaac agattcaact
    29161 gcaccttgag atatttggtt tacagtttca tttactgaat tccatacacc tgttctatca
    29221 tctaagcact cgcctttttc tattggttga caaggacctg ttgggtctaa ttctttagta
    29281 gccttagcat ctaaccagct aactgctcca caaagaccaa gtctttcagg agtaacaaca
    29341 caaacgtgag ctggtgcaaa tgattgacat aagttacaag aatagaaagt atcaacactt
    29401 tcatcaacta atgaagctaa tctttcatct ctagcattgt acttagctat tgcttctcct
    29461 tttaattcag aaactttttc agcatctgta attatagtta tttcacactt atcaactact
    29521 gattcaaatt catctaacat cttagcatat aaaacttctc ctatatgctc aagtctaaat
    29581 cctttatcaa atgcatcttt agagattctt acccaagcca tatctctttg tccaacgtgc
    29641 attacacctt ctatatagtt taagaagtag tggaaacgtc tttcaagaac tggctcgaaa
    29701 tcttcttgca tatttttacc agctatttta actattacag caagtggtaa tcttaataca
    29761 ccatctgcat caacttcatc tatatttggc cctattattt ctatcttatg gtcttcaact
    29821 tctgttgctt ctttcttaac aacaagctcc caagcttcag ttctgtttcc accaaactca
    29881 gcaaacatat cgctctttct aattctctca ccttcaaatg ctgctgcaaa tgaaactggg
    29941 ataggtattt cagtaacttt tatttttatt cctctagctt ctaatgaagt agctactatc
    30001 ttatcgtaat ctttttgagt taataggttc attggaactt caagaactgt ttggtcagtt
    30061 ataactggga atcctaaagc tattgctcca gcacctgcag atacaactaa ttcacttaat
    30121 ggtccaaatg cattaacaaa tgcaggaact ctattagctg tgtactctaa taatccgttt
    30181 aaatcaccag gagttaatcc accgaatatt aatgctgctc ttactgcaac agatacaacg
    30241 tgtataacag aagttacatc atatcctaga ggtataactc ttagctcaag acccattttt
    30301 actccagctt ctatagcttg gtctataact ttaccaacta agaaagttag taaaccttta
    30361 gattggtaat cttttataac ttttgctgct gattctgcat ctggacactc accaagaaca
    30421 actgcaacac caggtatatc tcctgtaact aatggtacac caagtgatct gattataggg
    30481 tcagttatat gacctgcaca tggctcacta tatggagcat ccatagttga atattttaat
    30541 gcttcaatta cttctgctgc taaagctgta gctaaaccag cattaaaagc atgttctagt
    30601 aaatgagttc tatttattaa agattttact acttctaaag caccttctaa gtcccctaaa
    30661 gtgttcatct tttgtcctgt tgcagcatat atacaaggta atgaatatgc tgtatcaggg
    30721 aaagcaactt tatgctcttt tccattcttt tctatagctt cagctaacat agcttgagcc
    30781 gcacctaaag cttgttctga ccctgtaaag attatattat atagattcat tctatttccc
    30841 cctttaatat ttacacctat tttttattaa ctatacccta aaaaccctag aaagcaaatc
    30901 caccttcatt taactctaag aaagagtctg catataaaga tgccccgttg attatgtcac
    30961 aagattttac agttttcatt aattctgggt cacatggatt cattatagct gaactaaatc
    31021 cattagccat tgccattgct aagaatgcac tatctaaaac aggtctaaca tgcttaggac
    31081 atccattaga tacgttagat aatcctcctg tagttaaaag tcccatctca gtcatcattt
    31141 ttatagcttc taaaacttct acttgttttt cttgcatacc ttttataact aagcataatg
    31201 ggtcaaatag tatatcagtt ggctccattc ctaacattaa gcctttttct aatatttctt
    31261 ggcagtaagc catacgctca tcattatctc ttgggatacc ttcttttgca cataaaccta
    31321 taaccattgc ttcgtattca gctgctatat ctattaaatc aaatcttgag ccagcatcag
    31381 cagagtttat tattggtttt gcattagttc tatcataaac tttaagtcca gcttcgatag
    31441 cttttttatt agctgtatct aatgctatag gaacattgtt gaactcagat tgaagtaatt
    31501 tgattcccca tgtcattatt tcttcgccat ctctttcggc aggtcctata ttaaaatcta
    31561 tatagtgtgc tcctgcttct aattgctctt ttgctctttt taagattgga gctgggtctc
    31621 tttctgctaa tgcttttctt attgaaggtg atatacaatg tattctctca cctataatca
    31681 taaatttttc catttataat gtcccccttt aaatttaata ttaatagtta gttaatattt
    31741 tattagtttg tttggcatgc tttttcttgg tatcctttta agaacttagg taattccata
    31801 gattcctctg gtcctataac tacattccat cctggtaagt tatcttctat atcaccttta
    31861 agtactgcaa cttttcctgg aatgataagg tctttacaat tagttacttc ttctacctta
    31921 ctttctttaa tgaaagcaga gattgagttt ccaccaaatt taccagcagc ccaagatgta
    31981 agaactgaat atccacctgc atctggtatt actaaccata ctggaacttt tgatctttct
    32041 atatcaccag caactatgaa gtaagttaat gcaaagtcaa cagtaactaa tactggagaa
    32101 ttttcatctg gattgttgat tggataaatc tttggttcaa ctctcattgg tctttgtggg
    32161 tcagtgtata tgttttgtct tagtgcaaat aatggtaatg ccttagcata actaatatca
    32221 tctattacta ttatagaacc gtattttata gtgaatattg atgataaagc aacttccatc
    32281 atagggtttg aattagataa tctatttgca aatactattg aaggatatcc aaatgttcta
    32341 tcttgctctt ttaaagctgt tcttctaact tgtatagcat tagtgtaagt atcttttatg
    32401 ttttctcctg ttacatctaa tactaattct ttatatccag cggcttgaat taattcaact
    32461 gtttcatata attcttctaa gctaccagct tttacaccta atggtaaact tgctccttta
    32521 actacttcta tcatatcttt gtagttctct ttagttgctc catataccat tggtctagca
    32581 tcttttaata cttcaacagc ttctttaact acttgtgcat catcacaagc taaaatataa
    32641 gctacttcta atccactgcc ttttatttta tctattaatt ttaaatacgc atctttatct
    32701 ccacaatact ctaaaacagc catttcaact ttcatttgtt caccaattct tacatagtca
    32761 acttttttca tgttagctat tttagcatct actgcttcat cactcataca agtacagaat
    32821 gaaactgcat atctatttct acttactaat gttttttcat gtctaaataa tactgtttct
    32881 ccacctagtt catactcaga tgcaccagca ccaactttta aagctttcat taaaggtgca
    32941 gtagcctctg ataattttgc tatagcgtca tcagacatat gtgggcattt acctacttct
    33001 acagctcctg aagcaacctt catagagaaa gccatacaag ttgggaatcc acaatcctta
    33061 cagtttttct ttggtgttaa tttaaatata tctaaagctt ttaatgccat tattttttcc
    33121 ccctaacctt aacaatttaa ttaagctaat gcgttaacca attcttttat agtttctatt
    33181 gattttggat gacgaagtat aactgcgttt gaaccaccta ctaaaacact tgctgcagtt
    33241 gaaacttcca ttgctatagt tctttcttct ggacaacccc aatctggctc atcttctatt
    33301 ggagctatag cttctttaac atgacctact tcaaaagcta ctggtgttat gataggcatt
    33361 tgtaatgtct tatcattttg accaaatgct gcaagtctaa ttctatccat agtagatgca
    33421 acgtactcat atccataacc aactgctgaa catccaacat tcataactat attttcacct
    33481 ttaacgccta gttgagttaa caatacgttt aattgtttag ctaggtttat atcaacagaa
    33541 gattcagctc ctactttatg tgcataagcc ataccagctg atgctcctac tcctttgtag
    33601 ttatcttcta ctgctgacat aaataagcag ttatgtccat ccaatgtttg agctaatttt
    33661 tcaaataatt taccatcttt ttcatgattt cctgaaccag ctacaactaa aggtaatttt
    33721 attgcttcaa ttactgcctt agctacatca gcacattcat caactgactt atctaatcca
    33781 tttgggtcag aaccatcaaa ttttaaacaa ataaaatctg cttgtgtatt agcttcaaca
    33841 tatttagccc actctactgg acaattagct acatctttgt ataattcctt atatgaatca
    33901 gtccagcttt caggataaac gtctgatatt tgtataccta tttttggaga attacctact
    33961 tctccatcaa aactataaaa aggtaataca ttttccccac ctaatttaat tgctttttcc
    34021 cctattccta cttcaacttc tgatattttt ccagaatatt tttgagtaga cattttaaat
    34081 gccatatttt tttccccctt aagcctattt taattctaat ttagcaaaaa tttctttcat
    34141 agccacttta gattttgaat cttcaggtaa attaactaaa ggaatacctg tagaatcata
    34201 ttcatatatc aattcatcca taggtacaac accgattagc tctaggttat gcttttcaat
    34261 ttcttcttta acaccatcat tcataacccc atttggaact ttatttacaa tcaaaagtat
    34321 tcttccaaca cttaacttta gttcctcagc taaatctctt attctagcaa cagcttgtat
    34381 gctacgtctt gagcaatcac taaccaataa aagtgtatca acatgtctag tgacttttct
    34441 acttagatgt tccataccag cttcgttgtc catgactaag tatttgtaat gaccagatat
    34501 tttgtttact tgttctctaa gtatcccatt tacaaaacag taacatcctt caccttctga
    34561 cctacccatt actaataagt catatccttc gccttcttcg attatagaat ttaatctaaa
    34621 ttgaagatat tgtgcctttg tcataccacc agggaatgca ttgcctaact tttctctttg
    34681 atttacttct tctcttattt ctcctattgt tgcttcaact tcgataccta acacttcatt
    34741 tatgttagca ttggcatcag catctacaac taatactggt ccctttttgt ccttaaccaa
    34801 ataatcaatc aaaagccctg tgagacttgt tttaccagtt ccaccttttc ctgcaacagc
    34861 tatattgtat cccattttaa gacttccccc ttaaatctag ccacagagcc ttatgtactc
    34921 tgtctgtcta ttataattta ggtacagaat gaacacattc tccatgtaca tcatgaagtg
    34981 cttccattag cccttcagat aaacttggat gtggatgtat tgcatcccct acttgttcta
    35041 ctgttaatcc tagatgaaca gcaagtgaca actctgtcaa taaatctgta gcatgaggtc
    35101 ctactactgc tgcacctatt atcttatcag tttctttgtc agctataact tttacaaatc
    35161 cttggaaatg tcctatagct tgtgcttttc caagacctct aaaatcaaat tgacctacat
    35221 tgtattctac accttcagct tcaagttgct tttcagtctt accaacacca gcaacttcag
    35281 gttcagtata aacacatctt ggaattgctc tataatctac taccttagtc ttacctaaag
    35341 cattttcaac tgctacgata ccttctttag aagcaacatg tgctaggaaa ggagtatcta
    35401 ttatatcgcc tattgcgtat ataccttcta cattagtttc aagatgttca ttaactacta
    35461 cttttcctct ttccatttca attcctatat cttctactcc agaattgtca aggttaggtc
    35521 ttctaccaac acatactaat gcatattgtg cttctataac ctttccatta gaaagagttg
    35581 caacagcctt accatcaact acttcacaag tttgtactcc aatacctgta ataaccttaa
    35641 ttttatcttt cttaaattgt ctaagtagtt gtttagctac atctttgtct tcatttaata
    35701 gtatttggtc aaccatctca actatagtta cttctgttcc taaggctcta aagaactgcc
    35761 ctatctcaca tcctataact ccaccaccta ctattaacat agactcaggt atctcttcaa
    35821 gtccaagaac ttcatcacta gttattacaa cttttccatc atatgggaac attcttggta
    35881 caactggaac agaaccattt gctagtatta tcttatctgc ttttatagtt tctactgttc
    35941 catcatcttt agttacttct atagtgtttt tatcaattaa ttttccaaaa ccattaacta
    36001 agtttactcc tcttttttca aataagaact ctataccact tattaattgg tttacaactt
    36061 tattttttct ttccattatg gcagtgaagt ttggcttaat tgtaccatct atttctatac
    36121 caaaatcctt tgcttctttt acagtattca atactcctga agaagcaaga agtgctttag
    36181 ttggtataca tcctgcattt aagcaagttc ctccaactct tcttttttca acaactgtta
    36241 catctgcacc aagcatagaa gcttttatag ctgctacata tcctcctggt ccaccaccta
    36301 ctactactat cttcatcttt aattccccca aacctaatat aatctacaat cttgcaatac
    36361 tataaacctg cggcatccag tatagcaggt atattctctt ctgccccaat tgccattata
    36421 tgaacaccat cacataaatc ttcttctttt aattgtttga taagttcccc tgccattttt
    36481 attccttcac ttacccagtt ttcttttcca gctgctctta atctttcgat ttgttcatct
    36541 ggaacaaata ttcctggtac atttgcagtc ataaatttag ccattcctgg tgattttaaa
    36601 ggtactattc ctgctaatac cttgcaatcc atatcccttg ttaattctct aaactttctc
    36661 attgtattta tgtcataaag tgcttgtgtt tggaaaaatt tagcccctgc ttttattttc
    36721 tttttcattt ttaataattg aacttctatt ggagaatatt ctggagttac tgatgctcct
    36781 agataaaaat ctggagaacc ttttaactta ttaccagcca tgtccgtacc tgccattaaa
    36841 gtctcagcag tttgaagtat ccccacagaa tctaaatcaa acactccctt agcttgtgga
    36901 tggtctccta cgctagtatg gtctcctgtt agtgccaaca gattgtttat cccaaataca
    36961 cctgctgaca acatttctcc ttgtatagct attctatttc tatctctccc tgttatttga
    37021 ataactggct ctaatccagc atcttttaat aatttacatg tagcaagaga agttgctctc
    37081 ataactgccg attgaaagtc tgttacattt gctgcatgaa ctcttccaac taacggcttt
    37141 gcacattcta ttaaatgtga aaggtcagtc ccttttggag gagccatttc agtagtaact
    37201 gcaaattttc cactttctaa tgtttctctt aataagctca tctctaatcc cccttttaac
    37261 cttctaaaaa aacttttatg aatttgctgc tgcttctttc tttttctttg cacttaaact
    37321 tcttggatta ttttgcttag aatagtcttt tggtggtctt atttctgcta agttatctaa
    37381 ttgtcctata gcttctagtc tttcatatat ctttatccaa gcacaatcat tctctgagtt
    37441 tacttcacac ttaccatttt tagctccacc acaagcccca ttcataagac ctttagcaca
    37501 catagttact ggacatatcc cacctgtcca accaagttca cagtctccac aagccttaca
    37561 ggcttcttca tattctccaa ctctttgtac ttcccctata aacaaagtat tgttggctgg
    37621 ataaactggc ttatctttta aattcttaac tattgtctgt gtaccatctc cacatgctaa
    37681 agataaaact gcatcagctt ccttagtctc ttcttttaga gcctttaaat cctttttaga
    37741 ctttaaaagg ttacaagcag ggtcaagcat tacatatcct aagatttttt tgccttcacc
    37801 ttcaagagtt tccttcattt ttaaaacttc ttcttcccca ccacttttac aagttgctgc
    37861 acattgatta caaccaacta aaaccagctt gtcaaaatct tttaagtacc ctagcacttc
    37921 ttctaatggt ttattttcag aaattatcat atctacttcc cccctaaacc ttccacatat
    37981 atatatctat ttattgtttt gtaatttgca agccttaact acatgttttg caagtataga
    38041 tgttgtaact gaaccaaccc ccgctggaac tggagttatc attgatactt tgtctaaaac
    38101 tgcatttgta tcaacatctc cacataaatt tccttcttca tcaacattta taccaacgtc
    38161 tataactacc gctccatctt taacaaaact ttcatcaacc atcttagctc taccaatagc
    38221 tgctattagc acgtctgcct ctgctgctac acctgataga tttttagttt ttgaatgaca
    38281 tattgtaaca gttgcgtgtt cacttaataa aagcattgat actggctttc caactaccat
    38341 tgatcttcca agaactgtta ccttacttcc ttttaaatca acattatagt gttttaatat
    38401 ctcaactact gctgtaggtg tacatggtgg aaatccactt ttatcccctt ccattacctt
    38461 agcagagttt attggactaa aacaatctac gtctttttcc ggtgcaataa catattttat
    38521 aacttcttca tttaagtgtt ttggaagagg tctaaaacat aatataccat taacattttt
    38581 gtcatcatta actctcttta atacatcaat atattcctct tgtgttatat cctcagctaa
    38641 ctctaacact tctgttgtta tacctatgtt ttgacatctc tttagtgctc ctctttcata
    38701 agataaatca tcacttcttg ccccaactct aactattgtt agtttaggat ttataccttc
    38761 tttaattagt aaatcgactt cttttattaa ttcttcacta atcttatcag ctacaggttt
    38821 tccttttata atttgtcctt tagttgacat tccttccata cattcacaac tcccctacaa
    38881 gcaaacttaa attaatttat tctatatacc acatattaat aacatagtat ctactttcgt
    38941 catttaaaaa ttattttcca agagcttttt caactttggc ataaacttca tcacaaattt
    39001 ttacaccatc ttcaactaac ttatctactt ctgtttttac cttattaaca tattctttat
    39061 cttgtataga atttatattt ataactacat ttaattgtcc accaagtata gcagctctta
    39121 aacactgaac tcctacacca acatcactta tagcaagtct tgaaccttta tcaactaaat
    39181 cttcatgtaa cttaatagct tcatagcaaa ctcttactat gtttaatggt acttcacaag
    39241 caacttttaa tgccttttcc attgtttctg cttttattct tttttcttct tctgtttctt
    39301 taggaagccc gtaagctttt gataatggta agaaacattc tgcatcatca tctatcattt
    39361 ttaataaatc tttttctaac tttcctgcct tacttaatat ctcttttaca ctttcttcat
    39421 actcagcata cttcttcttc cctattgtaa ggttacatac catactacct aaagccatac
    39481 ctattgcacc tactagtgca gcagctcccc caccacctgg tactgcttct ttggaagata
    39541 gtacttctac aaaatcaaca caagttttat ctgctatttt catgataatc ctccttgaaa
    39601 ggatgtagga aaatatctca aattgttcga gatattttac gaactatttt aagatatctc
    39661 ctactcttta tttataaatt aatttcctta gaataatcca gctattactc cattttcatc
    39721 aacatctatt ttttctgctg ctggaacttt tggtaatcct ggcatcttca ttatttctcc
    39781 agtaagtgca actataaatc cagctcctgc tgaaattgtt gcttgtctta cagttattct
    39841 aaatcctgtt ggtctaccta atttagtttg gtcatcagtt aaagaatatt gagtcttagc
    39901 catacatact ggaactttag taaatccaag tttttctaag ttagctattt ccttatcagc
    39961 ttcaggagta taatctacac catctgctcc ataaatctta gtagctatag catttatctt
    40021 gtcttttata gataaatcat cttcatagca gaatctaaag ttattttctt cttcatccaa
    40081 taatcttaaa acttctttag ctactgcaat tccaccttct ccaccttttg cccatacttc
    40141 agaaagagca acattaacac ctaattcctt acacttgtct tcaacaagtt taagttcagc
    40201 ttcagtatca agtgggaatc tgttgattgc aacaactgct ggtaatccat atacttgagt
    40261 tatgttttca acatgtttta ataagtttgg aagtcctttt tcaagagctt ctaggttttc
    40321 gttatttaag tctgctttag caactccacc attgtatttt aatgctctta cagtagcaac
    40381 tattataaca gcatctggtt ttaagtttgc cattctacat tttatatcta agaatttttc
    40441 tgctccaagg tcagcaccga aaccagcctc agttattaca taatctgcaa agtgcatagc
    40501 cattcttgta gctataacag agttacatcc atgagctata tttgcgaatg gtccaccgtg
    40561 tacaaatgat ggtgttcctt caagagtttg aactaggttt ggttttaaag catcttttaa
    40621 taatgcagcc atagcaccat tagcttttaa ttgtctagct gttacaggtt caccttcgta
    40681 gctgtatcca actattatgt ttcctaatct ttcttttaaa tcagatatat cacttgccaa
    40741 acagaacgct gccattattt cagaagcaac agttatatcg aatccatctt gtctaactgc
    40801 tccatcacct tttttaccca taccatcaac gatatttcta agttgtctat cgttcatgtc
    40861 tacacatctt ctccaagtta ttttcttagg gtctattcta agtgcatttc cttggtgaat
    40921 atggttatca agcatagcag ctaaaagatt gttagcagct cctatagcgt gaaaatctcc
    40981 tgtgaagtgt aagtttatat cttccatagg aacaacttgt gcatatcctc caccagctgc
    41041 tccaccttta acaccaaata ctggtcctag agatggttct cttaaagcaa ctaatacatt
    41101 tttgtctagt ttagcaaatg catcagcaac acctatagta gtagtagttt ttccttcacc
    41161 tgctggagtt gggtttatag ctgtagttag tattaactta gcttttttac cagtctctct
    41221 ttttagtaga ttgtagtcaa cttttgcttt gtatttacca taaagttcta catcatcttc
    41281 acctagtcct aatttttttg caacctctct aatatcttga ggcttagctt cttgagctat
    41341 ttcaatgtca gatttaaatc ccataactga atctcctccc acaacctaaa tagatttaaa
    41401 atataatttt tgtaaaaatt gtattaatat gtaaaaatta tattttataa gataattata
    41461 catgtaaaat tacttaaaaa ctagctacta agctattaaa atattcaaac ttaatagcta
    41521 gttatttatc taattactta cttattacct atctattgcc tatgtctaac ctttaaccaa
    41581 cttaaaatcc caaatcaaaa tttctatcta ttttatttat ccttaagtga cattaattta
    41641 tcttttattg ctttaatctg ttctttcgtt gtttcactag aatcatatgg agattgatta
    41701 gctctatcag aatcaataac atcttggtta taataaataa atcctaaaga ttctccatct
    41761 tctaagtttt ggattataaa ttcttcatct tccttatttc taattttatt tcctactaca
    41821 aatactttat ttacacctat atcatgtcca agtttcttaa cttttctata agtctgtaga
    41881 cttctctctc ctggttctac aactactata aaagcatcta caccttgggc tgttcctctt
    41941 cctaagtgtt caattcccgc ttccatatcc ataaccacta catctttatt ttgtagtatt
    42001 aaatgtgagc agagtctctt caaaagaaca tgctctggac atacacatcc agtaccacca
    42061 gaatctacgg ttcccaatgt aagtaatctt actccattgt attctttaca gaaattttca
    42121 gggatatcgt ctactttagg attcatctta aacatttttc caaatgaacc tacagaagca
    42181 gctgttctat ctgaaactaa ttttttcatt tctgatatag gtactattga ttcatatact
    42241 tcttttggaa aacctagtgc taaagctaaa ttagcatcag ggtcggcatc aacagcaaca
    42301 actctgtatc cgtcttcagc aaacatccta gagagcattg aagaaaaagt cgttttacct
    42361 actccacctt tacctgttat tgctatcttc ataatcccta ccacctttta ttactatttg
    42421 ctttttagta gttaatttta cagttaaata ttttttatac tctatatttt tatacactaa
    42481 aaataaacta cagctagtcc ttacaggaac caattaaatt taccctacta gcttttcaaa
    42541 gcagcatgta tagttttatt attctttaat attgtttata ttttatttat tcagtatatt
    42601 cattatattt tgatgttctt tactttaata tttgacttta ttcaacttta ttcaaccaga
    42661 aacttcttat aaaaacgttt attctataac ttcactattt tttaagcttc agccttttct
    42721 gccatctttt cttcaactaa tgcttcaaag tgaacacgtt ttttctctat atcttctatt
    42781 attgtagctg ctaactcttt tggatttgta tttacagtaa atgtagctcc aactttatct
    42841 tttaattcac tagttaatat atccactgct cttgaagaac cagctattgg aggcattatt
    42901 cctaaataag tgtctatacc agaagctaca acatagcatc ctatagcaac tgctttttct
    42961 gacatccact ctggagctat acctacaact ggaaggtcac acatatccat atctaagtaa
    43021 ttagctgctg ctccaactaa atctagtata cgacttatat caacacaaga acccatatgt
    43081 agtactggtg ggattcctac taatttacag acagttgcaa gacctttacc tgcatatttt
    43141 tcagccgcat cagattccat taaaccaaac ttagctgctg ctgaagctcc acaacctgta
    43201 gtaactacta ttatgtcgtt tttgattaat tctttcatta ttgttacgtg agcctcattt
    43261 gaaactcctt tagcattgtt acatccaact acaccagctg ctcctcttaa tactccagat
    43321 tttaaacagt ctgttaatgg cttaactgtt cctgctgggt ctatatgaga gtttacaact
    43381 ctgtctaatt gatttactac tgcttctaca ctatacccaa ctgttgcgcc tgattttaat
    43441 tcaggtataa gtacttttga tttatctcta tttttaaagt ttaaaatagc ttctttaact
    43501 attgctttag catcatcaag tgcttgttct tctctaaatt caatataagt tgaacctgtt
    43561 atcttagctt ttggagaagt tgttacaaat ttagtatggt aacaatctgc aactctagct
    43621 aatgcaggga atatacattg aacgtcaact attacagctt caactgctcc agttattatt
    43681 gcaagttctt gttgatggaa gtctcctgct atttttacac catgtctcat tgtaatctca
    43741 ttacctgtac aacacatacc tgctaagttt attccatcag caccaacttc tttagctaaa
    43801 gctactaagt ctggctcttc tgatgctaaa actatcattt ctgataatgc tggctcatgt
    43861 ccatgtaata ttatgttaac tttattttct tctaatactg ctaaattcgc ctctgttctt
    43921 cttggcactg gagttccaaa taagatatcg cttagacgag tacctatcat agaaccaccc
    43981 caaccatcag ccatagaagt tctaagactc atgtgtatta aactatctat atcaccagta
    44041 catcctatat gagtagagtg cattattgtt gcaatttctc tatctatagc tcttggctct
    44101 atagcgtatt ctttccatat tttttgtctt ggttctggtg cattttttat aaatcttaat
    44161 gtcccaaaag gttttccaaa ttccattaat gcaatttctg ccacttcatg tgctacatca
    44221 tagatatctc taccttctgt ctctacatcc cattctttag ctaaagtaat taacttagct
    44281 tcgtctctta ttttatagtt tccatttgga tcagctaatg ctaatgtatg tgctatatct
    44341 ctagcatggt ctgaatgggc agctgtccca ccagcaacca ttcttgcaaa gtttctacct
    44401 actatagtat gctcatctgc tccacataac ccccttggag tcttagggct tattctacat
    44461 ggtcccattc cacatattct acagcaaaca ccttgaagac caaaaccaca ttgtgcctta
    44521 aagccttctt ttctatcata cattgtttct acgccttctt ctctagcttt agctatcatc
    44581 ttctggctgt ttaaatcaat tgttaacatt ttttcatcca tattcctatc cccttttttt
    44641 gatttttaaa atcccccagg tgactgactt catgtcataa aataataaaa taaatgcttt
    44701 ctaagttgat tatatactaa ttttcagtgc tttgctttag atttaaatat ttttttaaca
    44761 aaattagata atacataaaa attttatttt ctacacttaa tttaagttga ttttatcgct
    44821 tgtttttggc tatttgttaa tatctaaacc tacttttttg atacttcagt ttaattaaat
    44881 tatgttttga tttttttaaa tcaaatttga aatttttcta gtcattttta tattattgca
    44941 gattgtttgt gtatttatta tctttcacta ctgtttggac ttattacaga tttttactcc
    45001 ctaaacttaa ttagtaaaaa cttcttagaa tagcattttt tggactaatt tttttgaatt
    45061 tttttatttt tcctacttta atattaatta tagcttcaaa ttgaacattt gtatatattc
    45121 atttgaagct ataattattt tttatataaa acttttttaa tacagcatta atttagacat
    45181 tttgactatt ttttctactt taattcattt atttcaagcg atttatccta tttcatattt
    45241 ttagctacaa tagccccata tgcaatagaa tataatttag attcatgtga atcagctctt
    45301 gacactaaaa ctataggagc ttttgcaccc ataattatac ctgctgattt agagtctgcc
    45361 atatatgtaa aggctttccc tattccatta ccaacctcta ttgttggaac caatatgata
    45421 tctacatctc cagatacttc acttttaaac ccttttatct cactagcttc ttttgaaaca
    45481 gctaaatcaa aagccagagg accttctaca attacatttt caccaaattc tccttcttta
    45541 caagcttttg ctaacatatc tgcatctaca gttgcttgca tcttaggatt tactttctct
    45601 ttagctgcca aacatgcaac ttttacagtt tccattccta aagcttttgc agcttttata
    45661 gaatttttta atatctttgc cttttgttca taatcaggag ctatattcat acctccatct
    45721 gtagttataa gtaatttatg gtatttttct aactcatata ccataacatg acttaataaa
    45781 ctatcagttc taagaccata gtctttattt aacacttctt ttaatatgac agatgtatct
    45841 aataatcctt tcattacaaa gtcggcttct ttacttgata ctaatttaac tgctatttct
    45901 gcacactctt tgatatcatc cttatccact attttgatac cacttaaatc aaatcctatt
    45961 tcttttgata tttctcttat tttgccttca tttccaacca atataggagt aattatattt
    46021 ctttctacag catcctttat tgccattaaa acttctttat catgagctgc tgctacagag
    46081 agtacaattt tctctcctcc cttaagttgt tctaaaatat catctaattt ttttatcaaa
    46141 agtaacccct cccttatata tatttaacta aataatacca tatttgctat accttttctc
    46201 aatttatttt ttatgttata aagaatttat ataactaaaa gacagtttaa tattttattc
    46261 tgggatttca tcaataactc ttaaaagctt tgcaggaaca ccacctacaa tagtattttc
    46321 tgcaacattt tttgttacaa ctgctccagc agcgataatt gcattatctc caatagtaac
    46381 tcctggaact acagttacat tagcaccaat ccatacattt tttcctattg tgattggaga
    46441 aggataagtt gtaccacgtt tctctggtgc aataccatgg ttaagtgtag ccaataccac
    46501 attatgccca atttgcgtat tatctccaat ctcaatcccc ccctggtctt gaaaatggca
    46561 actgctattt ataaaaacat tttttcctat tgtgatgttt tttccacaat ctgtataaaa
    46621 tggtggaaac ataaaaaatg attcatctac cttttttcca attaactcag aaaataaact
    46681 acggacttct tctggttcat gataagaaga atttaactta cttgtgattt tcattgcttc
    46741 attactcaac ttaaccataa attcatgtat ttctgattta ctagaaacag gttttctttg
    46801 attgatatgt gttaaaaatt cattgatatt cattttatac atcctttcaa tatgtgcttt
    46861 aatttatttg tacattctaa ataatatttt aataaaaatt aatttaattt atttttatta
    46921 aaatatcatt gcttctttta gtgtaatata caattatatc tatatcaaat atctatagta
    46981 aatacttaac tatacttaaa aagcatataa attgatataa ttatataata gataagttaa
    47041 tattgaggag ggataattat ggaaataaga gtattaagat attttttagc aattgcaaga
    47101 gaagaaagta tatctggtgc ggcaaccttt ttacatataa cacaaccaac actttctaga
    47161 caaattatgg aacttgaaga agagttggga gttaaattat tggttcgagg aaatagaaaa
    47221 atcaccttaa caaatgaagg taggctttta cataaaagag cagaagaaat tatatcatta
    47281 gttgataagg ttgaattaga atttgacaat cccaatgaga ttattagtgg tgatatatat
    47341 ataggaagtg gtgaaactga agctatgcga cttatagcta gaactgccca tcattttcat
    47401 caaaaatacc ccaatgtaag atatcacctt tttagtggga atgctgatga tgtgactgaa
    47461 aaattagaca agggactgct tgattttggt attttaattg aacctgcaaa tatacagaag
    47521 tatgattatg cacaaattcc tgctactgat gtatggggtt tactaatgcg taaagatagt
    47581 gcccttgcat cacaaagcac aataaatcca aaagatttat gcaatatacc tcttattatt
    47641 tcaagacaga cacttgttga taaagcaatt tctaaatggc ttcaagacag taatgaaaaa
    47701 ctaaacatta ttgcaacata caatttagtt tataacgctt ctcttttggt agaagaaggt
    47761 ctgggctacg ctctgtgttt agatagactc gtcaatacta cagaaaacag taatctttgt
    47821 tttagacctc tatctcctcc tttagaagct aaattaaata ttatatggaa aaaacatcaa
    47881 atattttcaa aggcagcaga aaaattttta cttcaaatac aaaaagattt ttcttctatc
    47941 atgttggata catctaagtt ggatacacct aaagaaaaat aaatcataat aaaaggtgag
    48001 agtgtctcaa aatgaacttt gcactgtata aggcactctt ttttatacaa agtaaaatat
    48061 atgttcatca tttcagcact aaaaaagagg cttatctcta ttttgagata gccccactta
    48121 accaataaaa ttaaatacaa cttaacaata tccttactta tttattctaa gttctcttag
    48181 acaagcaata gtaatttcat cttgtggatt taattcataa gctctttcta tatagtaagt
    48241 tgcatcatca atatcaccat tatttaaata agccattcct aaattgcaaa gtatttctgg
    48301 gtcttccttt atcttagccg cttgttcaaa atactctatt gctttatcta aattattctt
    48361 ataagcctca caaagcccca attccactat agtatccact tgattaggct ttattatcaa
    48421 tatcttctca agatacatct tagcctgctc tatttcgccc atacccttat atccaagtgc
    48481 tatcataaac agcaagttcc accaatccat atgttcttct tctaatggaa gtaacttctc
    48541 taatccttcc ttaaacttac cttggaatac aagtgtatat ccttcttcat attgaacttt
    48601 aaagtccatc ttgcccagat tctcttgtac ctcagctact aaatcagcat ctaaccctag
    48661 ccttaacgct tcttcccaag tcagcttagt ctttaaatat tgaccttgat tataataatg
    48721 gtagcctaag tgataataac ctaatgcaaa attctcatca acatcaatta ccttttcaag
    48781 cttagccatg gcttcaagta agaatgcatt cattgcctta tcatccatat ctttttgata
    48841 ctgtttagct atctcttggc aaacaatcgc atagttatac attgcatcta aatcatctgg
    48901 atacattgtt ataaatgctt ttatatatat taaagaatct gtatgttcac caatctcaaa
    48961 gtattttctc gacatatatc ccatatacga tttcaaatcc aaatcaatat cttttgataa
    49021 agcatttaaa aacttctcat actctgcatt gtttttaaac ttactatcta ttccaattat
    49081 atatatcatt gcatctgcta tagacattga atttaactta tcttgagcag tcttttcttt
    49141 tatccctttt actaatacct cattttttat aggtacatct aatccacctt ttggcacttc
    49201 atagcttttt aatttaaact ctccaccatg ttttatagtt ataaaagcta attcttctgc
    49261 tttttttagc aaatattttt ctatcttaaa atccatttta tcctcctaaa tacttaaatc
    49321 tctactttat gagttttaga tttctcaaat atttttttat catcatactc aaataagact
    49381 acattttcta cttctcttat ttctgtattt atatcatttt ttaaatccac aacattaaat
    49441 ctaaatggct caaaatgaac atattttatt atatgtttag ctggtttatc aacaaaacta
    49501 ggtaaatatg ttgataagtt atcattatct tgtaaaaata catggcatct attcttaaaa
    49561 tcatccacat ctagcttatt aaaaaactgt ggtatatttg atgttttacc cagtgatata
    49621 tagtcatatt ttaatatatc gttgaataca tcattatcta tgttgatttt ttcattatag
    49681 aaatccatca atattttata taactgattc tttccttgtg ccaaatcaaa gtagccattt
    49741 tcatcaaaat acttggcaaa aacctcaaag aatttaaaag ggcttttttt ataaaatctg
    49801 cctataatat atctcataga taacacaaag tttttagaat tgtagtatct ctccagtata
    49861 tcttctatat cctttagctt caaagtttct tcatagctta tataattatt gtataaaaac
    49921 tcatatggag cataatcctt atatttaaaa ccatgctcat ctgcaacttt tctcatacct
    49981 gtccctttaa tcatctttaa aaagcctaat tgcaaatgct ctatacctag attaaataca
    50041 tcattaaaag aattttcaaa gctcttataa tcttcataag gcagtcctgc aattaagtct
    50101 aagtgctgat gtatatttct ataagatgct acagtttgta caacatgaga caacttttta
    50161 aaatcatccc ttctacctac tgcatcaagt gttttttcat tcgttgactg aacacctatt
    50221 tcaaattgaa aaagaccttc tttacaatca gccaaaaact caagcatctt atcatctatc
    50281 aaatacgctg taacttcaaa atggtaagtt gtatatccat tatcattttt cataaggaaa
    50341 tccatgattt ccatagccac ttttctattt gcattgaatg tcctatctat aaactttatc
    50401 tgtgatactc ttgcatctat taaagctttt aaatcactct ttatcctgtc taaactaaaa
    50461 taccttagac ctggaatagt agatgataaa cagtattggc agttaaaagg gcaacctctt
    50521 gatgattcat aatacactat tctattttca tattcttttg gattcaagtt ttcataagga
    50581 ctaggaatct catccaaatc ttgaagtaat tccataggct tattcactat tatctcattg
    50641 ccttgtctat atacaagtcc atttacatca tttatttcca tctttccttg caagtgaagt
    50701 actaagtctc taaaaattaa ttctccctct ccataaagta tataatccac aaaatcatac
    50761 tttttcattg cctcataact atcataactc acttccggtc cgcccaaagc tattttagta
    50821 ttaggtctaa ttttttttag attatcacaa agtttaacta tatctcccac attccagata
    50881 tatgttgaga ataatattat atcatattca tttttatata tatcctttaa aatatagtcc
    50941 aaatcgttat ttatcgtgta ttctttcata ttaacttcta tcaaatctct tacaaattct
    51001 tttagatatc ttatagccaa atttgtatga ataaacttgg aatttaatgt tgttaataaa
    51061 attttcaaat atttctcacc tctttttaag attatactgt ctttttgtac cccttatagg
    51121 ttaaaatagt atatgtaaag tctaaataat atctatataa ttaatttatt aatttcaagt
    51181 aatgtgagga aaggaagttt tttatggaat taattgaaaa agtatctatc aactctttat
    51241 caaaaagaga tttactactt attataaagt ctcttgaata cactaatgaa aatactcaaa
    51301 ttagtgattt cattgacctt aggaataata tagtaaagga attatgtttt ttaactgaca
    51361 ctaaggaaaa agatttttta gattatctag aaaaaaatag cacactctaa taacctaaac
    51421 ctttttaaac tttaatatat aaatacctga tttagaattt atttttatgc ttaatatatt
    51481 atcattaaag gttttcgaca taactgttat ttgattaaat atagggtcta ttatagtatt
    51541 accttcttca agtcttataa gacttcttgg gtctatgctt ttattatatg ccttaactcc
    51601 aattttatat tttctcaatt taacaacata ttcggacata gaaaaaataa aatctatatt
    51661 atcttcattt aatttactat cttcacccaa aatggataat atagattttt ttatgctatt
    51721 aattccttca ttttctacag ttctatcttc catatataca tcatatagaa catttaaaac
    51781 atttaataaa atactttctt catcataatc ttcagatttc aaatcaatgt acttatcaat
    51841 taattgtatt gctttaatcc ttgccatctg aaactttaca acatctgatt tgtctaattc
    51901 tatagaaaat cctattatct tgtctttaat actctgtagt aattcgacat actctatttt
    51961 actattattt ataagattgt gcataatgga attatacacc acagaaccta ataaataatc
    52021 aaataaaagt tcttcttttt taaaataaat aacatacttt tttattagtt taataacctc
    52081 atcttcactt ttttgaatat tagtatttga taaaattagt ggtaataaaa tatttaaaaa
    52141 attgatattt cctatttttt ctccataaaa tctatagtaa ataagttcat ctctcagtct
    52201 attttcgtct atatacacac atctttgcgt tttatcatct attaaggatt ttgtatttat
    52261 tatagttaaa tctttaagag ccctacttgc actactaaaa gaagatgtgt agactttttt
    52321 tagtaattcg tcattcataa atatatcctt tctgaaaaat tgaatgtaaa taaattgtta
    52381 ttaaaaaaaa agagacagcc cgtttaagaa gctgtcatat atagggggat agtagtgtac
    52441 aaaaatcatt gtaatctact atctatatat tattatacga tactactttt ttatatgtaa
    52501 agcatcagtt ttcgacatcc ctatatttta cagttataca aattgcgtac taagttcaat
    52561 tttattcttt ttatttcaac attttatcat gctacattct ttcaggagcg tgcattccca
    52621 acaatttcag agaattttct aaagtttgtt ttgttgctaa aactaatgca agtcttgctt
    52681 ttcttatttc caaattttct actaaaattg gattgtcatg ataaaattta ttaaacgctt
    52741 gagctaaatc tagcataaat ctagtcacta tatgtggctc atttttcttt agagcaagta
    52801 aaatattctt attgaatgat tctataactc taagaacttc tgcactatct tcatcagcta
    52861 atagactata atctatatca gaagtcactt ctacttctgc ttttcttaaa actgcacagc
    52921 atctagcatg tgtatactga acatatggtc cagtctcacc atcaaaacta agcgttcttt
    52981 cccaagagaa ggtatagtct ttaattctac tattagataa ctcttggaat actactgccc
    53041 caacacctac ttgcttagat atttcatcca catttttagc atttgggttt ttagctagta
    53101 taatttcctt agttttatct atagcttgat ttaaagcatc ttctaaaaat actactcttc
    53161 cttttctagt cgacatagta ccttcttcaa gtgcaaccat accaaatcca acatgaatta
    53221 aatcttttgc ccaatcatat cccataagct caattacctt aaaccattgt tggaaatgta
    53281 agttttgttg agaaccaact acatatatac acttgtcaaa atcataagtt tcttttctat
    53341 atattgcagc agctaaatct cttgtcatat ataacgttga gccatcattc ttagtaataa
    53401 gtgctggtgg cattttatac tcttctaaat caacaattct tgctccttta gactctttta
    53461 aaagattttt ctcttctaat agttcgataa ctctgttcat tttatcagaa taaaaactct
    53521 ctcctgctaa agaatcaaat tctatatcta aaagtttata cactctgtta aactctttta
    53581 aactctcatt tctaaaccat tgccataatt cttgtgcttc ttcgtcacca ttttctaatt
    53641 tattaaacca tgctcttgct tcatcttcca tttctgggtg ttgttcagct tcatcatgga
    53701 atcttacgta taattttagt aattctggaa ttggattaga ctctactact tctttttctc
    53761 cccacttttt aaaggccact attaacttac caaactgagt tccatagtca cctaaatgat
    53821 ttattcttat agtcttgtat ccttgcgaat catatatctt atataaagca ttacctataa
    53881 ctgtagttct tatgtgccct atatggaaag gttttgctat atttggagaa gaatattcaa
    53941 ctattacagt tttatctttt ccaaaatcac tatgtccgta attttctttt tcatctaaaa
    54001 cttttttaat tacagtttct gctaattgag atttatttac aaagaaattt acatatccgc
    54061 ctaattgtat tacttttgtt atctctccac ttggttctat actttccgcc aattcacttg
    54121 ctatcatgtt tggagctttt ctaaacactt tggctaattt aaagcatgga aaagcatagt
    54181 cccccatatc cttatttggt ggaacttcta taagtgcctc tatctcttct ttcgataaat
    54241 cttctatttt ttctttaagg caatttgata ttgccacctt aaaatcttgc attctgttgc
    54301 tcctctctac attgttcctg gtttatattg tgcttatctc tttatgttaa atcaaatttc
    54361 gtgttttttc aagtatttca ttacagtgta aaacacttta gtaattatgt tttctgtata
    54421 tattaaaaat actataattg cagtttttaa tcacactatt attgattttt tataagactt
    54481 ttttctattt tattgtttct tgtactatcc agttgacttt atatactttt tttaatcttt
    54541 tatctatttt catacgtcaa tgctaatttt atatactttt cttttaatct tttattaatt
    54601 tttatacatc aatgttaact ttatataagt ttttttaatc ttttatctgt tttcatacat
    54661 caatgtcagc tttatatact ttttttactt ttttatctat ttttatacat caatattagc
    54721 tttatatact ttttttaatc ttttatctat tttctataaa tctttttcac tcttaacttt
    54781 tattccttct tcttctaata gccttgctgt tatacctttc cctggtatct ttttacctga
    54841 aaaactacca tcatatatta gattacatcc acaagagggg ctaccctctt ttagtattgc
    54901 ttcgctacat acatataaat ttgctatttt tagagtttca ttagcccctc ttacaaagtt
    54961 ttctgttaca tccttattat ctttagtaat tacttttcca tcaactatct cagcaggtgg
    55021 tcttggtgta gatagaccac ctaactgctc tgggcataca agtgtaaatt ctttgccttt
    55081 taaatattcc ttgacttttt cattatcatt attatcgcca ctatatttac aatttattcc
    55141 tattaaacat gcagatacca atatcataaa aatgtgctcc tatacaaatt cttaatatat
    55201 tctcatacaa attactaatg tattcttata caaattattt taatttaaca attgttactc
    55261 ctgctccacc ttctccatat tgaccacctc tttgtgattt tacatgtcta tttcttctta
    55321 aaatgtcttg tagccctgct tttaatactc ctgtacctat tccatgtatt actgttacag
    55381 actctaaacc tgccacatat gcatcatcaa gatacttttc tacttccatt atagcttctt
    55441 ctaggtttaa ccctctaagg tcaacttcat tttttacact accagatttt gaccttataa
    55501 tgtttctcgt tgatttagtt acatttgttg aaacatcttt gcgtgttttt tgtaaagact
    55561 taaaaggtag agtcatcttc attataccaa tttgcactac tgcttctttt ctctttttat
    55621 ctactgaaac tacactacca ttttgattta aagttattac cttaacttct tcacctggct
    55681 ttaagtcttt tatctcctta tttgatacct ttggaactat catacttttt actgttggct
    55741 gaagacttcc catagagctg gtcaattctt ttctaagttc ttctatctta cgattctttt
    55801 cttttgaagc tctttcttgt tcaagacttc taagttcttt tattataata tctacttctt
    55861 ctttagcttg tcttataatt gaaaatgctt ctgatttagc tttttcaatc atcttatctc
    55921 tttgactgac caatttttca agcttttcgt catactctac tttcagtttt tcaatctctt
    55981 cttttaatct ttcagcttct tctctatctt ctactgcttt gattctattc ttttcaacat
    56041 tctgtaacac atcttctaaa gctatgtttt ctgtatttat atattcttta gcacgtgaaa
    56101 tcacataatc acttagccca agttttctag aaatctcaaa cgcatttgat tttccgggaa
    56161 cacctataag taacttatat gttgggctta aagtttctat atcaaattca actgctgcat
    56221 tttctacacc tggtttagta agagcataat ttttaagctc actatagtga gtggtagcta
    56281 tacatttagc tcctacagaa tttatatctt ctaatactgc tattgcaagg gcagctcctt
    56341 caacagggtc tgttcccgct cctaactcgt caaatataac taaagagtct gctgttacgt
    56401 tttgtaatat agatactata ttcgtcatat gagatgaaaa tgttgataga ctctgttcaa
    56461 tactctgctc atctcctata tctgcaaata cattatcata tacacacata ctacttccat
    56521 aatcagcagg tatatgaagt ccactttgtg tcataagtgc aaatagacct acagttttta
    56581 ttgtaacagt cttaccacct gtgtttggac ctgttatcac caatgtatgg aagtctcttc
    56641 ctaaataaat tgtatttgct actaccttct ttttatccag cagtggatgt cttccatttt
    56701 ttatgtttaa atatttatcc tcatttaaag ttggttctat tcctctcatc tgtatagaaa
    56761 gttttccctt tgaaaatgca aagtccaatc ttccaagtat ctcttgatta gaaattaagt
    56821 cttcactaac ttctccaacc atagcagaaa gctctgataa aattctttct atttcttctt
    56881 gctcacctag ttttaactgt ctcaattcat tgttcatctc tactatagtc attggctcta
    56941 taaaaagtgt cgcaccagaa gatgactggt catgcactat accagctact tgcgacctat
    57001 attcagattt tacaggtact acaaatctat cacctcttag agaaattatt gcatcttgta
    57061 agtacttttg ataagtagtt gaacttatta ttgaatttaa ttttgaccta atggattgat
    57121 ttttttgggc tattcttctt ctgatatctc taagtgtact tgaagcattg tcagatattt
    57181 ctacttcact aattatagca ttgtatatct ggtcttctat gtccttgtat acatatagag
    57241 aatttgatag agattgtatt attggataat taaaatcttc ttcatcacta ctagataagc
    57301 tatttcttaa tcttctagcc actcttaagg tatctgctat cataatcaga cttcctgggt
    57361 caagagaagc acctatataa gctctcttta ccttatcttc tatatcatga ataccttcca
    57421 accctactga acctctcttt ataataattg attgagcttc actagtttct tctagcatag
    57481 atttcacttc tacaaaatca gtatttggta ctaaattttc tatatatttt agacctaaag
    57541 aagatgaggc tttcttcttt aacaaatcta ttattttatt gtattctaga actcttaacg
    57601 atttctcatt cattttctat attcaccatc ctcgatattt taactttttt atttaatttt
    57661 aaaaatgtat gttttcaagc atttccaata aaaactgcaa gttttatttc tttttcattt
    57721 ctaaaattat tatatttttt ctcttttaga tatattttac acatattttg tattatacta
    57781 tgtatgtagc tatctatata ttatacataa acatgcttta tttgtaatat aatctgttaa
    57841 aaaatcttct ttaatatttt taaaggagtt tattttagct tataaaaaaa aatagctact
    57901 tatatagata aattaaggag gaacatgagt catgggaaac gtattagaag gattaaaacc
    57961 agaaagtgtt tttaaaaact ttgagaaaat atctcaaatt cctagaggtt ctggaaatga
    58021 aaaaggcata agtgattttt tacttagctt tggtaaaaat ttaggtcttg aaactattca
    58081 ggatgaaagc ttaaacataa taataagaaa gcctgctaca aaaggatatg aaaattgtcc
    58141 aggtgtagtt cttcaaggac atatggatat ggtttgcgaa aaagaaaaga atgttgaaca
    58201 tgattttctt aaagacccta taaaattaag aattgatggt gacatgatat atgctactgg
    58261 aactactcta ggagctgaca atggtatagc tgttgctatg ggtatggcta tattagaaga
    58321 taatacttta gagcatcctg cactagaagt tttagttact gttaatgaag aagatggtat
    58381 gaatggtgca gatgcactag accctagctt aattaaaggt caatatatcc taaatatgga
    58441 ctccgaggag gaaggatact tattagttag ctgtgctggt ggtaaaactt gtgttgttag
    58501 tttacctgtt gaatacaagg aagttaaagg tgacaaacaa ggattattag ttgaggttac
    58561 tggactatta ggtggacact ctggtatgga aattgtttta caaagagcaa atgctaacaa
    58621 agcaatagct agagtattaa gtgtattgaa tgttgattat gaattagctt ctgttgatgg
    58681 tggtactaag cacaatgcta tacctcgtga agctaaatgt gtaatagctg ttaataaagc
    58741 tgatgttgaa tctgctaaaa aacaaataaa tgacatttta actgcattta aacatgagtt
    58801 tactacttct gaccctggca tgacttactc agtagctgaa acttctgtag acaaagttct
    58861 tactaaagat tgtaaagaaa aagttgttca aatgtcttgc ttaactcctc atggagttca
    58921 atcagtaagt cttgatatag aaggattagt tgaaagttct actaacttcg ctataatcga
    58981 aactaaagaa tctactattg aatttttaac ttctgttaga agttctgtta tgtctattag
    59041 agatgaaatc gctgatagaa taagactttt ggctcaagct ttaggtgcta attacgacct
    59101 tatagctcaa tacccagctt gggaatttaa aaaaggctca aaattagaaa aaatatgcag
    59161 tgaaacttat gagaaattaa ctggtaaagt tcctactgtt atggctctac atgctggtct
    59221 tgagtgtgga ttattacttg ataaacttcc tcatgctgaa gctatctcta taggaccaga
    59281 tatgtttgat gttcatactc caaatgaaca tgttagtatc ccttctgtag ctaatgtttg
    59341 ggattatgtt attgaaatat taaaatctat gaaccaatat taaatttaag ttttgattct
    59401 aagtagattt taattttaag taatctatat aaaattaact ctgtaaatta atactactgt
    59461 tagtataata tttactttca atattaactt atagaaataa agcctaatga tagataataa
    59521 catgtatcat taggctttat tgtaatttaa atattattaa gctttattct gttttaaaat
    59581 taattcttat actattttaa atctatttct tccttgtctc ttagaatcat aaagagcatt
    59641 atctgctatt tgatacagtt catcatactc ttgaccaggc tttgctataa ctacccccat
    59701 actaatagat aaactttctc catttggcaa cttaatgaga tgaatatgat tgtatacatc
    59761 attacattta ttaataagtt cttccttatt tattatatca ttgatataaa cactaaattc
    59821 atctccaccc aaacgaccta ctatatcatt ttttgcaaaa ctttcatcaa gtacctttgc
    59881 aacatcaata agtactttat ctcctaacaa gtgaccataa gtatcattaa tcgacttaaa
    59941 ataatcaata tctataatca ataaagcacc atttttttca gttgataaat tcaacaaatt
    60001 ttgtgcagtt aattttctaa tatatgctgc attataaata ttggttaaac tatccctttg
    60061 agccttatct aacaatctat tcttttcctc tttttcagaa tcaatattac atattttccc
    60121 gattacatac attggtattt ttctatcatt ataaattatt tttgaagtaa ctctaatcca
    60181 atgaaaagta tcatcaagca taatagaata catttcagtt gttccatttt cttgtgattt
    60241 tattacatca aaaaactttt tattatattc tttccttatt ttatctcttt cattttctat
    60301 attgccattt tcactttcct tatcattttt atccaaacca taataagtct caataccctt
    60361 ttctggcata gaaattatca atttatcttg cttataatca tactcaaaaa agtattcact
    60421 tgtcatttca tacaactgag tatgtttttt gagttctaaa gatatcttct cgttcatact
    60481 tgtacgagta tgcaaaccaa atgccataaa tccaataata caaattaata aactggctac
    60541 aataaaaata gtctcaattg gattctgttg cataatataa agcaacgaga agtcttgtct
    60601 atatgtagta ttttggtaga caattgattg cattttttct gatgaaatac ttataatagc
    60661 tttattaaat atattcaata attcttgttt atctttttta attataccaa aacaaatact
    60721 ctttgcttta taagtttgag gaactagacg cacattttta tacttaggtt gattcatata
    60781 gtactgcata gaataacctt cgccataagt gtaatctgca tagcctttat taacagcttc
    60841 tatacactct tctaaattat cataccaaac tatattctct tcaaactgac cataataatt
    60901 aatacctttg gctagagcta cacgttttcc atctaaacta ttctcattta atttattatt
    60961 aatcatcata gtatattgag tagaaagaaa aggccgagac ataactatat tatgttcacg
    61021 agagtattca taatcataaa tcattcctgc tacaatatca atttcacgct ttttagtcat
    61081 gttttctaaa tcttcttgag attttacagg cacaagttca aattctaagc ctgttttatc
    61141 acatatatga tttaacaaat caattgatat acctcttaat tcacctgtat ctttatctat
    61201 attttgaaat ggtggtttgt ttaaaagtac tcctactttt aatttttctg tctctttaat
    61261 gtaatcagtt tcttcatcag ataaaaacat ttgattgttc tctggtgtaa agtatttttc
    61321 atataaagta gttgaaaaat atgggtcttt ctgttcaata ttattaattg ctgagttaag
    61381 cttttgagtt aaatttgtac tacctttagg agtaatgaaa taaaatggtt ttgatgaaaa
    61441 ttttgctaca gtacgtacac cttctagtgg gttcatacta acattaagaa gtacatctgc
    61501 tttaccactc tttagtgctt ctagttgctc atcatttgtt ttacaatata ccaattcagg
    61561 tgacataaga ttcattttac aatactcatc taactcttta agtctagtat cagaattttc
    61621 tattacagca atacggattt ttttcacatc ttgtgaactc attatgttat caatatctgt
    61681 attttcatat aatgcttgta gtactgtatt tgctactcca taactatttc ctgcataatt
    61741 atatattttt tgcattggct cattgtataa catacctccc attatatcaa tttcaccatt
    61801 ttctaacatc ttcattaatt ttgtaataga ttcatttatc tctccaggaa cttgaacaaa
    61861 ttcataattc catccagtat actgtgcaat ttctagtaaa tattcatatg tatacccaaa
    61921 atagttacct tgctcatcta tttcagttaa acctttttga ataggataag caacacgaat
    61981 ggtacgatta tcattaccta tagcgttgat accaaaagaa aatatgcaag aagtgaatat
    62041 agatgtaatt acaataatta ataaaagtaa tttttttaaa ttcactacac aatcctccat
    62101 atagttaaga tttacagtat aaattactgc ataaacttgt agacatgtaa aaatagatta
    62161 gtatataaaa ggatatataa atctacttag aaatttaaat atccttaata tatacaatat
    62221 atttaaatta taactcattt atatgtctat tacaacaaat ttaccctgct aaatacctac
    62281 tctatatccc ataattttac aagttgtagt gaagtttaag ttctatctca cctcaaattt
    62341 agcagtgttt ctatttacag ttcttttata tttcacatct ggataaccca atataaatga
    62401 agtgataaca gcttcgttct cgctcattcc taacagttct tttatctttg gctctacatt
    62461 tgatgccata acaaaaaatc cattataaca aattcctaat ccttgagaat atgccataag
    62521 ttccatatta gatgcagcca gtcctccatc tacataagca cttccaccta gagacatatc
    62581 tcctacaact accataagta gtggggcatc ataaaataaa gaatcatttc cgttctcttt
    62641 atatcttttg tacattttct taaatgtatt tttatagata gaacgtacag ggtcattgtc
    62701 atcagtatct aatgccaaat tataaagacc ttgtattgcc agttctttca cttcttttag
    62761 cttttctttt actaatatgt atcttatagg ctgtctatta ccacctgttg gtgtgtatct
    62821 accagcttcc actatgtttt ttattttttc ttcttctacc tctatatctt tatattgtct
    62881 tatacttctt ctaaatttaa taaaattcaa taacttttcg ggttctaatt caaaactttc
    62941 acgattgtat tctattactt catttttatc aaatccttgc atttctattg catctgttgg
    63001 gcaaattgcc atacagtgac cacagttaat acagagaata tttttaacct ttgctttatc
    63061 atccttaact tttattgcat ttacaagaca gtctgattca cacatcccac agcctacaca
    63121 tttttctaaa tttatgtcta tcattccaaa ttattcctcc ttttaaaaaa tttactttag
    63181 tataaaacaa atagttgtct aagtcaattt ttattttttt aacaatatac tagccttaac
    63241 tacactttaa tggagaaaaa tatacataaa ttggaactta aattagaact tattcaaagt
    63301 aaaagataaa agaagtagat gtctaaaagt gaacttttta gttaattaga tattctttat
    63361 tgtatgaaat caagtggata tttatcattt caacaataaa aaaggcttac ctctattttg
    63421 gatatgtccc tgtcaagtag acagactaaa aaaaggctat ctttatgcac tgagatagcc
    63481 ccttttccca actactattg tttatcttaa tattagtcaa taaatttaat ttgctataac
    63541 ctgtaagtta cattttaatt tgatgtaact ttaaattaca tttttaagta atatctttaa
    63601 attatattct taaaatatat cattaaacta cattttaatt aatctaaaaa ctatatctta
    63661 attaatctaa gaaacttaca ttataatctt ttagtttccc attatcatat acaatctttg
    63721 cactaaagat atttccagtc ttagcccaat ttaagaacag cctgtcacct tcccacatat
    63781 ttaaatcgaa tattttatca ttatcaaccc aaattaaatt tccttcttta caatcattta
    63841 aatctttttc agataattca ccttcaaact catctgagaa atacaaaaac atataccaat
    63901 cttcttcatc tttaaatttt ggaaaagtta tcaacccttt atatgacaat gatttaagag
    63961 taagaccagt ctcttctttt acttctctaa ttacacattc ttctggagtc tctccttgct
    64021 caaactttcc tccaactcct acatacttac cttcatgtat atcatctttc tttttatttc
    64081 tgtacaacat caaagtcttg tcatcttttt ctatataaca aatagttgta agtttcatgt
    64141 atctcgcctt gctttctctt tatattctca actaattatt ttcagcactt tcaagcacat
    64201 cacttatatt cttcattgca ttaagagaaa gctctgcaaa ttcatcaaat ggaatcccta
    64261 tatcttctat acttctcatt gcatctctat ttacatttga agcaaatctc gtttctttca
    64321 ttcttttaat aacagactta gtctttacac tggtaagttt tttatctgga taaactaaag
    64381 ctatagcagt tataaaccca gttatagggt ctgctgcata tattgctttt tccattaggc
    64441 tagttcttgt aactcccatt ccatcatgat gaccaagtat tgctctatac atttcttcgt
    64501 caccgaagtt ttctttttta agcagttcta ctgttgttgt agcatgtccc tcacatattt
    64561 ctcctggctt tcttccaact atatctgaat ccaaatcatg taaaagacct gccactgccc
    64621 actcttcttc tttttctggc tctagtcttt tggctaattc tctcataaca gcttcaacag
    64681 cataacaatg ttttctcatt ctatcagttt ctaaatactt aaataaaatt tctaaagctt
    64741 cttctctcat tttcaccaat ccccctgttt tttcacatat atgatatttt tatatattaa
    64801 tacacataaa ttcaagtttt tatatatatt catgtatatt tttcatgtta tatctattct
    64861 acacctttat agtagtgtcc tgcaactgtt ccaatttcat ctaatttctt atacaagtct
    64921 gtagcccttt ttccaagttt ataattatta ctcaatacct caatgtgagc ttcaataacc
    64981 tttttaacca tctcactatc ttcaactgta aaatctatcc taaatacatc tattccaatt
    65041 tcctctaact catatagatt gtccaacata caagtaacct tcgaattgta aattgtactt
    65101 ctacagaata tatcttgtgt tatcctataa cttgcatccg taaagtctct taaagcataa
    65161 ctactttcct tacatttagc aactctcttg tcctttttac aatccctaac aactactccc
    65221 ataggacagt attctgtaac catcatagga gcatatccat atattactgc ttcaatttct
    65281 acatctgtat attttaaagt ttgtttaatt tcatttaagt ttagttcttg tgacaaacaa
    65341 actgtacttg ctccctcttc tttgaagtgg tttatacttt cactattgaa tgcatttaag
    65401 tagcaatcta tatttaagtc ttttttctta aagtattcca tagagcccca gttaccaatt
    65461 tgaaccttat taattccttt tatattatcc aatatctcaa attgcttgta ctctttattt
    65521 ctaacaatcc ttggtgctga atagattaat tttttgtcag tgactgctgt attagagtgg
    65581 ttcttattca aagtatctat tttacttgta tttgacaaag tatatatgtt atttgtattt
    65641 gaacccatta gttctttagg aatacctaaa gatgaagaag tatataaatc catagaaata
    65701 cttgaatcta tagaaatact tgagaccatt tgtaaagctt ttgataatgt atttatatct
    65761 tcataataga ttaaatctac attataattt aatactgctt ctaattgctc caagttctta
    65821 actttaactc taatcttagg aactgtatca agttttttct gtttatttac tctatttggc
    65881 tggtatttta atctattctt cttaaatttt ctatctttta tctttattct ttcttcatct
    65941 aaaagctcaa tacaatccct tctcatctga tttaacacac ttataggcat acttacacct
    66001 tcatccaggt caatttctat ctcttttaac ttatatggtg tatttccaag cttttgaatt
    66061 tgtgtttcta ttttttcttt acttaaagcc acctttatag ctttttcaac tattttgtct
    66121 ccttctacca ccgatttatt tccacaaaaa tcacttataa aaagctctgg ctttttacct
    66181 agtttaatac tcacttttgc acgtatatta gtttttatga actctttatc ttgctgaaat
    66241 gtagcttgta ctctatccat caattcgctg tcagaagtct tatatataag ctgatttctc
    66301 tttgcttctc caacaaaatc taattctatc aaatcccctt tatgtgctat tgtagttatc
    66361 tctccatcct ttattattct tccaatagta cctccaccta agttaattcc atcacctttc
    66421 ttaagcgtat tttctagcat tactctaagt cttttgttct ttctattata atctaaaact
    66481 tttccaatat atagcccttg attattaggt ctattagagt tcattatatc cttaccaact
    66541 tcacctaata tatatccttt tgtaaacttt ctattaaata tggtatacaa attatttatt
    66601 atttcctcag aaatacttat ttttttctta tctacaaatt cattaatcgc ttctctatat
    66661 cctgaaacca cagtagctac atactctggc tttttcattc taccttcaat ttttaaagat
    66721 aatacacctg cttcaattat tttatccaaa tcttctatag tacttaaatc tctaggactc
    66781 aacaaataat ctccattact ttttactact tctcctgtat ttatatctat caactcatac
    66841 ttttgtctac atggctgtgc acacctacct ctatttcccg acctattgcc tatcatacta
    66901 ctcataaggc attgacccga gtaacataca cataaagctc catgtacaaa aacttctata
    66961 tctacagttg tattttcaca aatccatttt atctcatcaa catttaattc tcttgctaaa
    67021 acaactctat caaaccctac actctgaagg tattttacat cttctaagga atgtgctacc
    67081 atttgagtgc ttgcatgtag ttcaaagtca ggtaatagtt tttttataag tcttgccatt
    67141 cctatatcct gtactattaa agcatcaata tctatatcgt ataaaaattt tacatactct
    67201 acaaaatctt ctatttcata ctgttttatc aatgtattta cagtaacaaa gacttgcact
    67261 ccccttatat gagagtattt aacagcctca atcagctcat ttctatcaaa gttatttgca
    67321 gatgctctag cactaaagtc tttaccacct aaatacacag catttgctcc gttttgaact
    67381 gctgctttta atgaatcaaa agagcctact ggtgcaagta attctatttt tttcatattt
    67441 ttctcctcta tttatacttg ttaggttaat ataattatat ctataactta aatatttgta
    67501 ttaaatttat atatttctta ctatatttta aattcttcaa tcaatttata tattagttat
    67561 ttatatttgg t
//
LOCUS       DAMJWC010000012        66656 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMJWC010000012 DAMJWC010000000
VERSION     DAMJWC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.012"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            125..871
                     /gene="cdtR"
                     /locus_tag="PC503_000963"
     CDS             125..871
                     /gene="cdtR"
                     /locus_tag="PC503_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF2526976.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
     gene            1260..1442
                     /locus_tag="PC503_000964"
     CDS             1260..1442
                     /locus_tag="PC503_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526977.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            1778..3345
                     /locus_tag="PC503_000965"
                     /pseudo
     CDS             1778..3345
                     /locus_tag="PC503_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(3997..4998)
                     /gene="trpS"
                     /locus_tag="PC503_000966"
     CDS             complement(3997..4998)
                     /gene="trpS"
                     /locus_tag="PC503_000966"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF2526978.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(5021..5719)
                     /locus_tag="PC503_000967"
     CDS             complement(5021..5719)
                     /locus_tag="PC503_000967"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF2526979.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(5762..6002)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6093..7496)
                     /locus_tag="PC503_000968"
     CDS             complement(6093..7496)
                     /locus_tag="PC503_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2526980.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            7993..9069
                     /locus_tag="PC503_000969"
     CDS             7993..9069
                     /locus_tag="PC503_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2526981.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(9172..10014)
                     /locus_tag="PC503_000970"
     CDS             complement(9172..10014)
                     /locus_tag="PC503_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2526982.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            10198..10770
                     /locus_tag="PC503_000971"
     CDS             10198..10770
                     /locus_tag="PC503_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2526983.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(10933..11205)
                     /locus_tag="PC503_000972"
     CDS             complement(10933..11205)
                     /locus_tag="PC503_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526984.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(11332..12204)
                     /locus_tag="PC503_000973"
     CDS             complement(11332..12204)
                     /locus_tag="PC503_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2526985.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(12500..15607)
                     /locus_tag="PC503_000974"
     CDS             complement(12500..15607)
                     /locus_tag="PC503_000974"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF2526986.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(15700..15932)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16107..16634)
                     /locus_tag="PC503_000975"
     CDS             complement(16107..16634)
                     /locus_tag="PC503_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF2526987.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(16669..17454)
                     /locus_tag="PC503_000976"
     CDS             complement(16669..17454)
                     /locus_tag="PC503_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF2526988.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(17464..17721)
                     /locus_tag="PC503_000977"
     CDS             complement(17464..17721)
                     /locus_tag="PC503_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF2526989.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(17740..18198)
                     /locus_tag="PC503_000978"
     CDS             complement(17740..18198)
                     /locus_tag="PC503_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF2526990.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(18238..18942)
                     /locus_tag="PC503_000979"
     CDS             complement(18238..18942)
                     /locus_tag="PC503_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF2526991.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(18952..19587)
                     /locus_tag="PC503_000980"
     CDS             complement(18952..19587)
                     /locus_tag="PC503_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526992.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            19968..21008
                     /locus_tag="PC503_000981"
     CDS             19968..21008
                     /locus_tag="PC503_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2526993.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(21471..22826)
                     /locus_tag="PC503_000982"
     CDS             complement(21471..22826)
                     /locus_tag="PC503_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF2526994.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(22852..23121)
                     /locus_tag="PC503_000983"
     CDS             complement(22852..23121)
                     /locus_tag="PC503_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2526995.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(23411..25366)
                     /locus_tag="PC503_000984"
     CDS             complement(23411..25366)
                     /locus_tag="PC503_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2526996.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKLVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(25549..27024)
                     /gene="spoIVA"
                     /locus_tag="PC503_000985"
     CDS             complement(25549..27024)
                     /gene="spoIVA"
                     /locus_tag="PC503_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF2526997.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(27196..28491)
                     /locus_tag="PC503_000986"
     CDS             complement(27196..28491)
                     /locus_tag="PC503_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2526998.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDESGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(28675..30084)
                     /locus_tag="PC503_000987"
     CDS             complement(28675..30084)
                     /locus_tag="PC503_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2526999.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGC"
     gene            complement(30136..31275)
                     /locus_tag="PC503_000988"
     CDS             complement(30136..31275)
                     /locus_tag="PC503_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2527000.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            31594..32244
                     /locus_tag="PC503_000989"
     CDS             31594..32244
                     /locus_tag="PC503_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2527001.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(32401..33420)
                     /locus_tag="PC503_000990"
     CDS             complement(32401..33420)
                     /locus_tag="PC503_000990"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2527002.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(33451..34065)
                     /gene="plsY"
                     /locus_tag="PC503_000991"
     CDS             complement(33451..34065)
                     /gene="plsY"
                     /locus_tag="PC503_000991"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF2527003.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(34100..35419)
                     /gene="der"
                     /locus_tag="PC503_000992"
     CDS             complement(34100..35419)
                     /gene="der"
                     /locus_tag="PC503_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF2527004.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(35453..36781)
                     /locus_tag="PC503_000993"
     CDS             complement(35453..36781)
                     /locus_tag="PC503_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF2527005.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(37019..37219)
                     /locus_tag="PC503_000994"
     CDS             complement(37019..37219)
                     /locus_tag="PC503_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527006.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(37221..38153)
                     /locus_tag="PC503_000995"
     CDS             complement(37221..38153)
                     /locus_tag="PC503_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2527007.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(38198..39130)
                     /locus_tag="PC503_000996"
     CDS             complement(38198..39130)
                     /locus_tag="PC503_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2527008.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(39185..40474)
                     /locus_tag="PC503_000997"
     CDS             complement(39185..40474)
                     /locus_tag="PC503_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2527009.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(40503..41195)
                     /locus_tag="PC503_000998"
     CDS             complement(40503..41195)
                     /locus_tag="PC503_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527010.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(41210..41971)
                     /gene="pgeF"
                     /locus_tag="PC503_000999"
     CDS             complement(41210..41971)
                     /gene="pgeF"
                     /locus_tag="PC503_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF2527011.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(41968..42429)
                     /gene="nrdR"
                     /locus_tag="PC503_001000"
     CDS             complement(41968..42429)
                     /gene="nrdR"
                     /locus_tag="PC503_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF2527012.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(42451..42714)
                     /locus_tag="PC503_001001"
     CDS             complement(42451..42714)
                     /locus_tag="PC503_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2527013.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(42818..43591)
                     /gene="sigG"
                     /locus_tag="PC503_001002"
     CDS             complement(42818..43591)
                     /gene="sigG"
                     /locus_tag="PC503_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF2527014.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(43683..44405)
                     /gene="sigE"
                     /locus_tag="PC503_001003"
     CDS             complement(43683..44405)
                     /gene="sigE"
                     /locus_tag="PC503_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF2527015.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(44430..45302)
                     /locus_tag="PC503_001004"
     CDS             complement(44430..45302)
                     /locus_tag="PC503_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF2527016.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(45592..46866)
                     /locus_tag="PC503_001005"
     CDS             complement(45592..46866)
                     /locus_tag="PC503_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2527017.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(47150..48307)
                     /gene="ftsZ"
                     /locus_tag="PC503_001006"
     CDS             complement(47150..48307)
                     /gene="ftsZ"
                     /locus_tag="PC503_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF2527018.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(48497..48850)
                     /locus_tag="PC503_001007"
     CDS             complement(48497..48850)
                     /locus_tag="PC503_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF2527019.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(48949..49623)
                     /locus_tag="PC503_001008"
     CDS             complement(48949..49623)
                     /locus_tag="PC503_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2527020.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VDLFAK"
     gene            complement(49628..50326)
                     /locus_tag="PC503_001009"
     CDS             complement(49628..50326)
                     /locus_tag="PC503_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2527021.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(50349..51089)
                     /locus_tag="PC503_001010"
     CDS             complement(50349..51089)
                     /locus_tag="PC503_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF2527022.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(51359..52585)
                     /gene="murG"
                     /locus_tag="PC503_001011"
     CDS             complement(51359..52585)
                     /gene="murG"
                     /locus_tag="PC503_001011"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2527023.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(52603..53733)
                     /gene="spoVE"
                     /locus_tag="PC503_001012"
     CDS             complement(52603..53733)
                     /gene="spoVE"
                     /locus_tag="PC503_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF2527024.1"
                     /translation="MPKENLKKQIDIRVKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(53785..55140)
                     /locus_tag="PC503_001013"
     CDS             complement(53785..55140)
                     /locus_tag="PC503_001013"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF2527025.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSDNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(55159..56127)
                     /locus_tag="PC503_001014"
     CDS             complement(55159..56127)
                     /locus_tag="PC503_001014"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF2527026.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(56168..57541)
                     /locus_tag="PC503_001015"
     CDS             complement(56168..57541)
                     /locus_tag="PC503_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF2527027.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVIDGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(57708..59687)
                     /locus_tag="PC503_001016"
     CDS             complement(57708..59687)
                     /locus_tag="PC503_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF2527028.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(59699..60046)
                     /locus_tag="PC503_001017"
     CDS             complement(59699..60046)
                     /locus_tag="PC503_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527029.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(60527..61462)
                     /gene="rsmH"
                     /locus_tag="PC503_001018"
     CDS             complement(60527..61462)
                     /gene="rsmH"
                     /locus_tag="PC503_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF2527030.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(61492..62238)
                     /locus_tag="PC503_001019"
     CDS             complement(61492..62238)
                     /locus_tag="PC503_001019"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF2527031.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(62632..63918)
                     /locus_tag="PC503_001020"
     CDS             complement(62632..63918)
                     /locus_tag="PC503_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2527032.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(63933..65198)
                     /locus_tag="PC503_001021"
     CDS             complement(63933..65198)
                     /locus_tag="PC503_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2527033.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            65514..66611
                     /gene="ychF"
                     /locus_tag="PC503_001022"
     CDS             65514..66611
                     /gene="ychF"
                     /locus_tag="PC503_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF2527034.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        21395 a        11797 c         7260 g        26204 t
ORIGIN      
        1 caagcataaa tataccttaa ttctaactat ccttaatctt atttatctcc tagtgttatt
       61 ttatgtattt tctataaaat acttttgttt ttttactttt gaatttttta taggagggta
      121 tttagtggat atattaatct ttgataatga tgtttgtttt ggaatgaaac taaaagaaaa
      181 aataaataat attttaataa aagaaggttt tgataatgat gttgtaagat tatatcataa
      241 tgcaaatttg ttattaaaag agcttactga aaaaaataaa gtaagaatat attttatagt
      301 tgtagacgca aaatataaga taagtaatga attatgtgat ggattatgga tagcacaaaa
      361 aattagagaa tcagattata ttagtccaat catatttctt acaaatcata tagaaatgat
      421 tttagggatc ttcgattata ggttagaagt tatggacttt atactaaaac atgatatgga
      481 aattgctgaa agtaaaataa aagcttgtat taaaattgct cacaaaagat acattaaaga
      541 aaaaaattat cgctctaatt tttttactat ctattcagat ttctcactat ggaaaatttc
      601 atttgatgaa gttatatatt ttgaaacaag cactattcca cataaaataa aattagtgac
      661 tacttctaga atatttgaat tctataaaag tttaaagtct ttaccagatt tagatgcatg
      721 ctttatccgt gtacataaat cttttgtagt taataaatat catattgttt ctctcgacct
      781 aaagaaaaat aatattaaaa tgagtaatgg ccatatatgt cgtatatcta atacatatag
      841 aaatatttta aagaatatta ttaaaacata ataaatagaa aaaggagatg tctcaagata
      901 aaaatttgaa ccatctcttt tttatacaaa aagagtaatc cctaagaatc ctctatataa
      961 taatcatatt gtgaaaaaac acatactgac tatatcatat ataactacta ttagatatta
     1021 taacaattgt tcctagatta tgattcgata agatagctca ttaaatcata aaagtacgaa
     1081 atagtctctt taaaatattc agttgttatt ttgtactgac atatcatata aatacatatt
     1141 tttatgatat atacctacat attttatgaa atttatataa aaaattctta tttagattat
     1201 ataatctaaa taaattaaaa ttcaaaagtt aactaaacta atatttgtag ggagaataaa
     1261 tgaaaaaatt taggaaacat aaaagtatta gtaattgtat atctatattg ttgatattat
     1321 atctaacttt aggtagtttg ttacctaata acatttatgc acaagattta caaagctata
     1381 gtggaaaagt ttgtaatact acttacaagg ctcctataga aagatcagaa ggattttttt
     1441 aaagataaag aaaaggctaa agaatgagaa agaaaagatc aaaaacttga aaaatctgaa
     1501 aaagaagtat taggatcata taaaaaagat tctatagaga taagcaaata ttctcagaca
     1561 agaaattatt tttatgatta tcaaatagaa gcaaattctt gagaaaaaga atatagagaa
     1621 cttcgaaatg ctatatcaaa aaataaaata gataaaccta tgtatgtata ttattttgaa
     1681 tctccagaaa aatttgcatt taataaagta ataagaacaa aaaatcaaaa cgaaatttca
     1741 ttagaaaaat ttaatgagtt taaagaaact atacaagaca aattattacc atacaacaga
     1801 taattcaact gctgttcaaa atagcaatgg ataatcatga aatactggat taagtataaa
     1861 caaaggagaa tctgcatata taaatgcaaa tattagatac tacaacacag gtactgcacc
     1921 tatgtacaaa gtgacaccaa caacaaattt agtgttagat ggagatgcat tatcaactat
     1981 caaagcacaa gaaaatcaaa ttggcaataa tctatctcct ggaaatactt atctcaaaaa
     2041 aggattttca cctatggctc ttaacacaat gtatcaattt agttctagac tgattcctat
     2101 aaattataat taatttaaaa aattagatga tggaaagcaa attaaattag aaacaacaca
     2161 agtaagtgga aattttggta caaaaaatgg ttctggacaa atagtaacag aatgaaatag
     2221 ttggtaagac gatataggtc aaattgacag tatttctgta tctattatat tagatacaga
     2281 aaatgaatct tacaaaagaa gaattactgc taaaagttta caggtcccag aagataaaac
     2341 acctgaactt acaattggag aagcaattga aaaaactttt ggcactacta aaaaagatgg
     2401 tttgttatat tttaataata taccaataga tgaaagttgt gttgaactca tatttgatga
     2461 taatataggc aataagatta aagacagttt aaaaactttg tctgataaac aaatatgtaa
     2521 tgttaaactt gaaagaggaa tgaatatact tataaaaaca ccaacttact ttactaattt
     2581 tgatgattac aataattacc ctagtatatg gagtaatgtt aatactacaa atcaagatgg
     2641 tttaaaaggc tcagcaaata gattaaatgg tgagacgaag attaaaatac ctatgtctga
     2701 actaaaacct tataaacgtt atgtttttag taaaattcaa aaaatccttt aacatataat
     2761 tcaataattg taaatataaa agtaaaagaa gaaaaaacgg attatttggt actagaacaa
     2821 ggatatacaa aatttagtta tgaatttgaa actactgaaa aagattcttc taatataaat
     2881 atagcattaa ttgatagtga tacaatatac ttagataact tatctattac agagctaaat
     2941 agtactcctg aaatacttga tgaaccagaa gttaaaattc caactgttca agaaataata
     3001 gttacacata aaatatattc tgcagatttt aaatttaatc caagtacaat aaaggcttat
     3061 ataaatggta tgtattttac accaacataa actaataaag aagctctcga ttatgtccaa
     3121 aaatatagag ttgaagctac tttacaatat tttggattta aagatattga aactaaagat
     3181 aaagaattgc gtaattattt aggagataca aatcaaccta aaactgattg tgttaatctt
     3241 aggagttatt ttacaggtgg agaaaatatt atgacataca agaaattaag aatatataca
     3301 attactcaag atgatagaga gttattggtt cttagtgttg attagtatca aatgatttaa
     3361 atttatcccc acaatacaat atgtatttac cttataaagt attaaaaaat taactttata
     3421 aggtattttt tatttaaata ttatcttctt ctaatatatt cttttttaga actatattgt
     3481 attaaaaaga taattatctg tatcatatca cctatatata aacataaatt catttaatta
     3541 tataaattta aaaaatattt ttttgatata ttattgacaa ttttcattat aagagttaaa
     3601 attaactcat aaattacata ttgggtataa aatacaatgt atgttagaag ttgtttcaga
     3661 aggctatggt tttctgattt ttttatgctc agtagtgata tgcaaaaaag acaaagttga
     3721 catcagttaa cttttacctt tattctactt tccccaaagt aagaataatc taaccccttt
     3781 gagatgagca aaagctcatc tttttttatt atcaaaagat gctgtctcaa aatagagata
     3841 atcctctttt tcattgttga aatgattaaa atatatttta tttcatacaa aaaagagtgc
     3901 ctcatgaaca aaagttcact ttgagactct ctctttcata tcatatacct ttttaataac
     3961 tttaaaattt atttatcaag taaagatagc taataattag tatcttctct ctataaatcc
     4021 aactttttta taaacttttc taagagtttt tctagcttgt ttttcggctt tttctgctcc
     4081 catactatat attttttcta aataatcttt attattaaga aggtcaacat atttttctct
     4141 tataggtctt aaagcttctg atactacttc agccacatct tctttaaata tgccataacc
     4201 ctttccttca tacatgttta caatctcttc tacactcttt ttacttaaat tagaatatat
     4261 atcaattaga tttttaatac ctggttgttc atcattgtat tttacaacac ctaaagaatc
     4321 agtaacactt ctttttatct ttctctttat agaatctgaa tcatctgcta atagtataaa
     4381 tgcattttca tttgaatcgg atttactcat ttttttagtt ggctcttgca aactcatcac
     4441 tcttgctcca ccttttgggt agtatccttc tggaactaca aaagtaggtg aaaatctatt
     4501 attaaatcta tttgctaaat cacgagctaa ttctaaatgt tgtttttggt catctccaac
     4561 tggaactagg tcagtttgat acaacaatat gtcagcagcc ataagaactg gatatgtgaa
     4621 taaacctgca tttagatttg cttcactctt ttgtgattta tctttgaatt gagtcattct
     4681 acttaattca cccatataag tcatagtatt caatacccac ataagttcaa catgctcttt
     4741 gacatgtgat tgtataaata tagtattttt ttctgggtct aatccacaag ctatatattg
     4801 agcaagtaat tctatagtat tggctcttaa aactttaggg tcttgaggta ctgttattgc
     4861 atgcaaatca actatactat aataacaatc ataattgtct tgaagttcag tccagttttt
     4921 tatagctcct aaataatttc ctaaagtcat tttgcctgat ggctgtgcac cactaaatat
     4981 aacttttttt tcactcattt ttttgtacct ccttatatat ttatattgat tttaacatat
     5041 ttaaaactat gtctttagag ttattggcag catcatgtac aaatacatca taagtaacat
     5101 cagcacttcc atctgcctta tcagacattg ctcttattat tacaaatgga gtattattta
     5161 aatagcatac atgagctata gctccacctt ccatttctcc acaatatcca ccaaaatcat
     5221 ttactaattc ttcttttaat tctttagaat ttataaattt atctcctgta actactcttc
     5281 cttttaatac tttatgagtc tttacttctt ccacagaaga tttgtaagca gcatctataa
     5341 gtctttcatc tgctttaaat acagaagtct tcattcttgg tataactccc ttagggtctc
     5401 caaatgctgt agtgtctaca tcatactgta tagcatcagt tgatattact atatcattaa
     5461 catcaagttt ttcgtttaaa gctcctgcaa cacctgtatt aacaatagca tcaaccttaa
     5521 attcgcttat tagtatctgg gcacaaagag cagagttaac cttacctatg ccacacttta
     5581 ctaacactac attcttacct tccaaaattc ccttataaaa ttctaagcta gcttttttta
     5641 tagtctctct aatatccatt aaatcaacta aaatactaac ttcttcatcc attgcaccta
     5701 taattcctat tacgttcatt tttcctccta aattttctat attaaaaaat ccgtcctaaa
     5761 tcaataggac ggatatattt tccgtggtac cacctaaatt tatatacact caaaattgaa
     5821 tatatatatc ttaatatatg ctataacgtg catacacgat atcaaatact ctgtaatatt
     5881 aaattacatt tcattttact cctcaaagac ccattcaata aatacttttt attaagttct
     5941 cagcatcctt aattctctgt gcaaaaatat atttatttac tatttcttat ctcaggattt
     6001 aatttattaa tttctttatt ttataatatt ccttacacta taaattgtca actatatatt
     6061 ataatatcca aaagaaattt ttaaaataca ttttatttag ctgttttctt ttcatatcta
     6121 ttccataacc atagaccaga taatataact agaagacctc caccaatcat ctctatctca
     6181 tatataacat tttcagcaaa tgtaggcata actggtgctg cagataataa tatacccact
     6241 acagttacaa ctaaaaccat ttttgctaaa cctaggcaag tacttgttga ttttgccata
     6301 gtataaggtc taatttcatc tggtctctct tttcttagtt taatataaga agcatataac
     6361 aatacatatg ggaataatgc agttaatgct gtcatagtta caagaacatt gtatatagca
     6421 tcaacagaag gcattaatgt agtcaccaat agtattatag taactattat tgcttgaagt
     6481 ataactgctt tagaaggtat cttgtgttca tttacctcta ctaaactatc tggaaatatt
     6541 ccttttttaa cactaccaaa taacattttt attggtgatg ctatgtaaag aactattgct
     6601 cctaatactg aaaaagctat accaaaagct attaattgaa ccaaccaaga accaattcct
     6661 aaagacgcac aaacagcaga aagtgcatct aatacacctt tagaagcagt aatttggtct
     6721 ggtggtatta tcattgttat tgcaattgaa cctaatacat ataatgaagc tactattcca
     6781 gctgatatta atattgcctt agggaagttc ttttcaggct tatctatttc tgttatgaag
     6841 ttagcagcag tctctgctcc tgctaaacca aacattatag ctgatatagc aacaaatgca
     6901 tccatattaa gttttggagt cattgaagct attgtgtatg tagaagctat atcatgtttt
     6961 ttcaacacaa atactgctac aaatgaaaat attataagta tagcacttgg tattgttgaa
     7021 cctaatgcac ctgtattagt aaatattttt gtaaaactta ttcctttagt tgctataaga
     7081 gataatgccc agaatattat taaagataat ataagtacaa acatcttatt atcagcaagg
     7141 gctggatttc ctattgtata agaaacattt actgctaaga aagttaaaaa tgaagaatac
     7201 caaaatattt tagctgtcca gtttaaccaa gaaactaaaa atccatactt ttctccaaag
     7261 gcttccttaa cccaatcgta aagacctcca tcaccttttt gatatgtaga agctaattca
     7321 gcacaaatta aagctcctgg tacaaagtat ataaatgaga ataataacca cataggtatt
     7381 gcacctaatc ctaaaccaaa gcttgatgct gtagatttag ctatccatct tataccatat
     7441 aaagctgata cattcataaa taccaaactc cataggccta tttttttctt ttccatccta
     7501 atttaatttc ccctctctat taattatttt aaatttaatt tcaaaattaa taaaatagat
     7561 tcattattat taaactgata tttttcaaaa tatttgcata ttcaaaaaca gttttaataa
     7621 taaaccttaa atactttgaa atcaaatctt attaaaaatg ataaatttaa aagttttacc
     7681 actttaattc taatgatact aaatttttaa aattgtttca atattatttt attataaaat
     7741 tttatttatt atttttcatt agtatataaa aagataaaat acataacttt atagacttaa
     7801 tttattactt ttatagaatt ttcacaataa aaagtcattt tacttccgta tttaatgcaa
     7861 aagtagaaat taaacttaat ataaaaaata tataacaaat tttttttata tttctagaag
     7921 aaaagtatac tcttttttgt ttaataatgc taaaattgat ttgtattgaa ttttgattag
     7981 gaggaaatta ttatgaaagc tcaaagatta aatgctgtac ttgaacaaat gaaaaaagat
     8041 gatatttctc aaatgttagt aagtgaccct acttctatat tttatcttac aggagtacta
     8101 atccatccag gcgaaagact attagcatta tacttaaatt taaatggcaa taataaatta
     8161 tttataaatg aattattccc agtttcagaa gatttaggtg ttgaaatggt ttggtttaat
     8221 gatactcaaa atccagtaga aataataact gaacatatag acaaaaatgc tactatgggt
     8281 gttgataaaa actggccagc tagattctta ttaaacttaa tagaattagg tggaggaagt
     8341 aagtttgtaa attcatctta tataatagat actttaagaa tgtgtaaaga tgaagaagaa
     8401 aaagagttaa tgagaatagc ttcaaaatta aatgacaagg ctatggaaca acttaaagct
     8461 actgtttctg gtgaacttac agaaaaacaa cttgttggta aattatctaa aatatatgaa
     8521 gacctaggta ctgatggatt ttcatttgac cctattatag gttttggacc taatggagct
     8581 aatccacatg gtgaacctgg aaatgcactt gtgaaaccag gagatgcaat aatcttagat
     8641 ataggttgta taaaagataa ctattgtgct gatatgacaa gaactgtatt ctataaagaa
     8701 atacctgaaa aaggtagaga aatatttgaa atagttcttg aagctaataa gagagctgaa
     8761 gctattgtaa aaccaggtgt tagattctgt gatatagatg ctgctgctcg tgactacata
     8821 actgaaaagg gatatggaca gtacttcact catagaactg gtcactctat aggacttgaa
     8881 gttcatgata aaggagatgt atcttctata aatacagata ctgtacaacc aggaatgata
     8941 ttctctatag agccaggtat atatttacca ggtgagttcg gagttagaat agaagattta
     9001 gtacttgtta ctgaagatgg ttgtgagata ttaaacaaac atgacaaaga aatatgtgta
     9061 gttggttaat tctaaaatca atttgataaa attaaaaagc catataaaaa tgttttaaac
     9121 atttttatat ggctttaatt tctcaatcta tgatttattt caatccatta tttatattgc
     9181 agttattaag attgcaccct ttgaagtata tgtccccatc actgaaccaa tttcacagat
     9241 tacaacatct ttgtatttta catccttttc cataacttcc cttacctttt gagccttttc
     9301 tgggcaatta gcatgtccta taaataaaac cttttcttct ttatctttaa tttttgactc
     9361 tactaaagta atcagctttt tcaaactgtt tccttcacct cttgccttat ctataggagt
     9421 tacaacgcca tctgcaactt gtattatcgc cttaaaattt aaggtattta taatttttcc
     9481 tgctattgga tttattctac cacccttaat agcattttct aaagtttcaa gtgttccaaa
     9541 aaatggagga ttatctttat atttatttat tattgaaaca atctcttcaa tttcttttcc
     9601 ttcttttatt aatattgctg cttttaacac taattgtcct attccaattg acccactaag
     9661 tgaatctata acctcaactt tcttgttatt tccttccttt tcaaacatat cttttgctaa
     9721 aagtgcacta ttataagtcc cagataatcc tgaacttata ttaatcacta atacactttc
     9781 ttcctgacaa tggtatgctt ctaaaaattt atcaggagaa ggacatgatg tttttggtag
     9841 tactttactc tcactcattt ttctatagaa agtttcatta tctatttcct ttccagatat
     9901 ataactttct tctccaaaag atacatttaa accaacaact tctatgttgt atttttctat
     9961 tatatcatca ggtaagtcac atgcactgtc cactatcaat tttattttat ccatattaac
    10021 ctcactataa gatattattt tatttattca gtcggtcgta cgaccgattt aattattatt
    10081 ttatatattg aatgaaaaaa agtcaataga tatagattct cgctttattg acaataaata
    10141 tccataagct tataatgtta ttaatttgtt ataaatatac atggaaaggt aggttttatg
    10201 aaaacaaata atatgaaaca ggctatttta tcatctgcaa ccaatttaat agccaaaaat
    10261 ggagttcaaa atactagcct tgctgatatt gcaaaagatg taaatataag taaaggtact
    10321 ttgtattatc actacgcatc taaagatgat attatatatg atattgcgga tactcattta
    10381 gaagttataa ctagtgctat actaaactgt gtaaaaaatg tcaaatcaaa aaattctcaa
    10441 atagaaatgg ttaacttaat cttagagaaa atatctacta tagaaagtcg tggtagggta
    10501 catatgtatc ttatttgtga ggcaattact tcaaataatg atttaaagga aagaataaga
    10561 ttaaaatata ttgaatggag aactactctt aaatctgaaa ttgttgaatc actagaaaaa
    10621 tataatagta gcgaaaatga acaggatgct gaatcatttt cttttttact catgtcaata
    10681 gttgatggtt tagttgtcca aagtttatta aaaacagaaa aaatacctta tgaaaatata
    10741 gcttcttttt tagttaatca ttggatttaa acttaatact tagataatta ataaaagtga
    10801 actatttaag ttatctactt taacagttca ctttcttatt tattctcaat aatttttact
    10861 taaaacattc aatttttatt taaaccttca tggaatcaca aaataaaaat ctcttataaa
    10921 tttaaaatgt ttttatttat gttcatgtgt atgcccatct gaatgttcat gaccatgtgt
    10981 atgtgtatgc tcatggctat gctcatgagt acctgaaaaa ccatcatcat gattatggtc
    11041 gtgacctaca ccatttacat gctcatgttc atgcccatga ctgtgagaat gttgatgtga
    11101 atgttcatgg ttatctcctc cacagcatcc ttctcctcca gtcccacaac acccacttgt
    11161 atgtggatta tgatgatttc ttactacaaa tctctctctt aacataattc ttatacctcc
    11221 tagtatatta ttgagtactt catgtacccc attaactaca gtatacatct aactaggtat
    11281 aatctcaata catatggcat tttttaacat atataattaa catatataat cttaaagaaa
    11341 tttatcctta aaacctccac cttttacttc ttcaacgtta ttgacagaaa taaaagcttc
    11401 actatccata tcataaatta aatctttaaa tttacctatt tcatttgcag atattatgca
    11461 ataaatcatc tttttcttat tttgtgtata tgcaccttct gcctccaaaa aagtgactcc
    11521 tctacccatt ttattcatta tcactttgga tatttcatca tatttatttg atattaaaag
    11581 tatagatttt tttctatcaa agcaatcttt tcctatatcc atagtaaaag aaattatata
    11641 cattgtaatt aaagtgtaca tcaccaattt agctccaaat aaaaaagctc ctgcacatac
    11701 tacaaaaaaa ttaataaata aaaatgtatt tttcataggt atatcatact ttcttttcat
    11761 tatggctgct attatatcaa gtcctccagc agtagctctt gctttaaaag ttaaccccat
    11821 acctatacca gttaatgcac caccataaat acactgtagc atagtatcat ctattgggaa
    11881 atatttagca atatcttgtg ttagccccag tgctagagaa aatagtaaca tattgacaaa
    11941 acttattagc aaaaatttat tatcaaaata ctttctagct ataataaata ttggtatgtt
    12001 catcaagaaa cttgatattc cctgattaat accaaataat ttgtataata taacacaaat
    12061 tccagctact cctccactta ataacttggc tggtgctaga tataaattta ttcctaaggt
    12121 tgatagaatc atacccaata taataagaca atattgtaaa aatatattat tatcaatact
    12181 tagcttttta ctttcaccat acatcaaaac gcaccccttt gcataataaa taaaccaccc
    12241 tgcataacac acgataaatt tacaaataaa tttatcagaa gtagtttcct aaaaatatta
    12301 ttcatcctca cttaaacgtt tattcattaa tattctatca catgacataa ataatttata
    12361 tgatttatat agatttattt attgtaaatt ttggaatatt aaaacatttt attgaataga
    12421 taattatatt acataaaaaa tccctataga aatctataaa ctaatttcta tagggatttt
    12481 ggttaactaa ctattatttt tattttttta taacttttat acctgtcata tggtcattta
    12541 agttttgttc ctctaaagat ttatcatcta ctctgtttat ttctaaagct aaagtttcag
    12601 acttgatata ttcattaaaa tggtcaacag ccttagcaat ttcatcatca ccacagtatt
    12661 ctattactat attatctaat acttcaaagt tattagattt tcttaattgc tgtactttag
    12721 atataaattc tctagcataa ccttcattaa ttaactcttc agttagctta gtatctagta
    12781 taacaaaaag attgttttca acagatacat taaatccttc cttagcagtt atacctatta
    12841 atactaaatc cttattaaat tcaaaagctt caccatctaa atcaactgtt aaagtctcac
    12901 ctttttcaag tttattagca gtttcatgag catttaattt acttaatgct ccaacgaata
    12961 aattcatctt agaacctaat aatggccctg cttccttaaa gtttggtttt aaactaaagt
    13021 tcatatactc atctaaatcc ttagcaaata ttacctcttt aacattaagc tcttctttta
    13081 ttaaatcaac tacatcactt attgtatctt caaacttacc atctactaac actttttgta
    13141 atggttgacg aacttttatt ctttctactt ctcttgaagc tctacctaaa gtaactaagt
    13201 ttttagctaa atccattttt tcttctaatt tagtatctac taactcttca ttacatttag
    13261 gatattcagc taaatgaaca gatacttctc ctgttaagtt tctatacatt tcttctgaca
    13321 tatatggtgc aaatggagct atagctctac aaagaccatg taacaattca taagttgtat
    13381 tgtacactgc ttttttatct tctgttaatt cagttgccca gaatcttctt cttgaacgtc
    13441 ttatatacca gttagataaa tcatcattta taaaatcttg tatcattctt aaagttttat
    13501 ttaactcaaa tatagctaaa ttttcttcta catctttcat taaattattg aacttagata
    13561 atatccatct atcaagttct ggtctatctt tatattctac aaaaaattca gttggattta
    13621 tatcatctgt gtttgcatat aaagtaaaga agttatatac attcttcata gtacctataa
    13681 atttactttg gatttctttt aatccatcca tatcaaattt agttggagtc catggtggag
    13741 aaacatatag taaataccat cttaatgcat ctgctccata ttggtcaaat aattccattg
    13801 gatttactgt atttcctctt gatttactca ttttcttacc atctttatca agtacaagat
    13861 ctggaactaa aacactctta tatggtgctt ttcctaatac aaatgttgat actgcaagta
    13921 atgagtagaa ccaacctcta gtctggtcta taccttctga tatatagtca gctgggaaca
    13981 attggtcaaa gttttcctta ttttcaaatg gatagtggtg ttgagcaaat ggcatagccc
    14041 cactatcaaa ccaacagtct ataacctctg ttactcttgt cattggtttt ccacattttt
    14101 cacattttaa gtgtatatca tctacatatg gtctatgaag ttcaactgtt tctggattta
    14161 catcttctat agctttttca gctaattcag ctcttgaacc aactgaatct gtatgaccac
    14221 attcacatct ccatatagga agtggagttc cccaatatct agttcttgat attgcccagt
    14281 catttagatt ttctaaccag tttccaaatc tcttctctcc tacaaaactt gggaaccatt
    14341 ttacaccatt attattttct attaatttat ctttaagttt agtcatctct atataccagc
    14401 ttggttttgc atagtatact aatggagttt gacatctcca gcagtgtgga taattatgaa
    14461 ctactttttc tttgctatat aatttatttt cagaagctag ccattttatt atttcaacat
    14521 ctagcccatc ttccattaca aatctacctt cccaaggagt agatgtaaat ttaccagttt
    14581 catctactgg ttgaataact ggtaaatcat atcttttacc tgtgttgtag tcatcttcac
    14641 caaatgctgg tgctgtatga actataccag ttccatcttc agtagttaca taatctccta
    14701 ctgtaataaa aaatgctttt ttgtcaactt ctacaaaagg cattaattgt tcatattcta
    14761 aaccttctag gtctttacct ttcatttctt ctaaaacttc ataatcttca cctagtactt
    14821 tatcagctaa aggtttagat acataatata cctcatcacc ttttttaact tttaaataat
    14881 ctacatcagc atttactgtt aatgaaacgt ttgatggtaa agtccatgga gttgttgtcc
    14941 atgctaagaa gtattcatca gcatcttttt tcttaaattt agctataact gtattagttt
    15001 ttacttcttt atatccttgt gcaacctcat gactagcaag accagttcca catcttgggc
    15061 aataaggaag tattttatgt ccttcatata tatatccttc tttgttgaat ttgtttagta
    15121 tccaccatac agactctata tagttattat ctaaagttat atatggatta tctaaatcaa
    15181 cttcataagc cattctctca gtcattattc tccattgttt ttcaaatgag aaaactgact
    15241 ctctacattt ttggttaaat tcagctattc catattcttc tatttgttgc ttgctagtaa
    15301 gacctaactc tttctctact tgtatttcaa ctggtaatcc atgtgtatcc caaccagctt
    15361 ttctctttac ttgataacca gacattgttt tatatctaca aactgaatct ttaagcgttc
    15421 tagataaaac atggtgtact ccaggatttc cattagctgt tggaggtcct tcatagaata
    15481 cgaaacttgg gtcatctttc cctttttcta aagttttttc aagtatattt atgtctttcc
    15541 aataatcaaa aacttgtgct tctgcttgtt ttacagaact gtctaccaat ggcttaaatt
    15601 tcgccatgta aatcaccctt tcctactaaa tattataatt ccaaaatttt ttattctttc
    15661 acataaattt aaatactaaa aaactcgccc cctttaaacc aaagggacga gttataaatc
    15721 gcgttaccac cctaattcta tatgtaaact aaatactagc tacatataac actctaatag
    15781 tataacggta ctaaccggca cagcttagta gaatttaatc gttcagcctg cagctcaaga
    15841 gtgattttta tctttataaa ttcattggtt ctcagcatac ccaattctct gtaaaattat
    15901 ctaaagataa atgtctctat caacgctttt aaaaatttat ctgtgtttat atgaaattct
    15961 ataacaaata atttgaatag tcaatatatt tttgaaaaat ataataattt ctatttttct
    16021 tacattttta tcctattttt aatctttgtt atagatttct caaactcaca caattattct
    16081 acataaaaaa taaacaaatt acaagcttat tctaaagttg tagcagcttc atcattacta
    16141 taattataca ctgttgttcc ttcaaatgca tttacacatt tttcatctac atcataaaaa
    16201 atctcatcaa cacttcttat ttcatcttct aacagtgatt taaatttatt tctaaatatc
    16261 ttaaattctt tgactaaagc atcatactct tttcttatct ctataacacg gttattagct
    16321 tgttctataa tttgtctagc ttttaaatca gcttcttcaa caattatctt agccttttta
    16381 ttagccgcgc tacaagtgtc ttctgctgca ctttgagcag ttattaaagt agcttttagt
    16441 gtttcttcaa tattttcata cttgtttact tggtcttgat ataaccctaa tttttcttta
    16501 agagctgtat tttccctaca tagagattca taatcttcct tgatgatatc taaaaattca
    16561 tcaacctctt catctctata ccctcttaaa ccttttttaa actctttatt ttctatctca
    16621 attggagtta gcattacatt tcctcccagc tataatttaa attagtcctt atacaattaa
    16681 tcttgcttga acttttattt ttcctttttt agtaatatct cctatttgtg ttaccttagc
    16741 tcttcctttg cctctaatag aaatcaaatc atcgtttttt actattttag aagttgaagt
    16801 tatcttttca taattgacat ggactttttc tccatttatg tattttgcac tatcttgtct
    16861 agatatattg taaataccac ttatcacaca atctaaccta tctgaagata ctgtaaatga
    16921 tacttcttta tattttgaag aactattaac aatattttct ctggaaattt cctttacaat
    16981 tacattattt cttgaaacct tttctaagtt tacaattata aaatcgcaaa tatcactact
    17041 tacaactact tgacaaaagc tatcatgtat aattatatct ccaatttttt ctctttttat
    17101 acctagaccc agtattgacc ctaagtaatc tttatgagat atatttttaa atttgaaatt
    17161 cccttctatt tgtaaaaatc taagagtatc ttctatatct tcatattcca tgtaaaatgg
    17221 ataaataaat acagtgcttc tttcagcttg ttcataacct ccatccacac tgtattttat
    17281 ttcatttgta gaatttaata ttgctacagc atttttcact tcatatggat taagaaactc
    17341 cgtagactta acatcatagt tttttataca actattagcc ttgtctatca ctttaaacat
    17401 tttatttttc aagtctatat cctttatgtg atttgttagt tttaatttat ccatcctatc
    17461 accttagaat ataaccaata ctaattgtct taggaacatc aataatacta ttgcaattaa
    17521 aggagaaaaa tctataggtc catttgtata tttatacatt atagacctta ttggcccttc
    17581 tattggctct gtaagatttt ccaaaatatc aaaaatttta ctttgtcttc catttggaaa
    17641 ccaagtcatc aagcttttta taactatcat ccatgctatt atatctaaaa gataataaag
    17701 tgcaattctt attgttccca tatattaacc gcctttttac tatttatttt gccaagggaa
    17761 gaatgcttta ctttctaatt cttttttcat atttgcatct atatccacat tattaggagc
    17821 tagtataaat attgatttag aaaccttttg tatacttcca tctaagacat aaactgcccc
    17881 attcataaag ttaaatatag atttacgaac ttcagaatta gtcaatcctt ccaaattcac
    17941 tataactgcc cttctttgtt ttagatggtc tgctatagtt gcagcttcat cataaacctt
    18001 aggttcaact attacaactt tcatttggct agttgtatgt aaatttacaa ttttatttgc
    18061 ttttgcagta ctaaagccac tgttcatttc ttcttcttga actatatcgt ccatgccact
    18121 ttcatattca tcttcaatgt aatcttcttc ttcatcaact atccaattct taaatttaga
    18181 tattattcca tttgacatta ttaacttcct ccttaaaatt tattcaaatt tgagtaatta
    18241 ttttttattg tagtttcttt ctccaaagat tgatgttcca actctaacaa tggtagcccc
    18301 ttcctctata gcaatttcat aatcgtgact cattcccatt gacaaaacat ccatccctac
    18361 attagggatg tttagttctt ttatttgttt tgataaatct ttaagacctt taaatacacc
    18421 tcttatctca tcttcatctt ctataaaagg tgccattgtc attagaccct ttatttttat
    18481 atttttatat ttttctgaca cttctttgac aaagtctaca acttcttctc tatcaagtcc
    18541 atgcttagac tcttctttag atatattcac ttgtactaag caatctattt ctctgtttat
    18601 ttgttctgca cgtttttgaa tttcttcgca taatgcaatt ctatctaaag agtgtatcat
    18661 acaaacttta tcgattatgt acttaacttt attggtttgc aaagttccta tcaggtgcca
    18721 gtttaattta tcacctataa tatcatactt tctagctaat tcttggggtt tattttcacc
    18781 aacagaagtg attccttccc tcattgcctc attaactaag tctacatcaa cagtctttgt
    18841 gactgccaaa agggtaatct ctttgctgtc tctatctact ttttttgcag ctttatcaat
    18901 tttgtttctt atctcagaca aattatcttt aatagaaccc attattatca cctactttat
    18961 ccttatattt gtgtttatac tgttaggtct taaaattatt ttgtcatata gattaacact
    19021 tgtaactcca tttatgtcat ttttataata atccacaaat acagaagatt cattctcata
    19081 agttattcct tctaatatga caaattttac actttgtgat tgttcatcaa ttacatatac
    19141 accacgttta ttgtcttttg tttttataga agttttaggt atttttaaac attccatctg
    19201 attatatatt atatcaaatt cttcgacact tgtatcctga tttgcaacaa tttggttact
    19261 tatttttaat tttaccatta ttttattatt attttcatat attttgtaaa cttttgcatc
    19321 tagtttttgc tcatgatatt caattattac attttgattt ttttcaaagt tattagaatc
    19381 ttctttactg atgtatgtag atagataatt actttggtca ttggcatctt tttctatagt
    19441 tccttttaca tgaatctttg catcaacttt ttcatttttt aacaccaacg tatctacatt
    19501 tttgctaatt atcattacta atatattaaa tactaaatat ataagaatac caagtatcac
    19561 taatctggta tattttacct ttttcaaaga ctctccccct ataaaattac tttcattata
    19621 agtacttctt ctaaaaaatg tttattcctt ttttataaga taatatttta cgttctaata
    19681 attatttttt ccatattaaa tttatttttt atcaatcttc ctatacaaga ctgcattatt
    19741 tatatataat tgtattataa agtataagtt taatttacat tttatacgtt aagcttactt
    19801 tatatatttt tatagttatt tttattttta gatgcaatat aaaaccaatt aagatttaaa
    19861 ataacttttg ttatgttgac atttatttag gtaatcattt atgaattagg ataacgttat
    19921 cacaacaaaa gtttatgtcc taaaaaaaat acaaggagga ttttcttatg tcagaaattt
    19981 tattaggaac aggtttactt ttattggttc tatgttgttt cacaattttt agttacaagg
    20041 ccccatatgg tatgaaggct atgggagctc tagcaaacgc tgcatgtgct actttcttag
    20101 tagaggcatt caacctttct ttacttggtg atgttttagg tatggaattt tttagaagtg
    20161 ttggagctgc taatggtagt cttggtggag ttgctgctgc tatacttgtg cctttagcct
    20221 taggtgtatc tccagtttat gcagttttaa taggattatc ttgtttagat ttttctatat
    20281 tatctggatt cgttgctgga tactttgttt ctttcttaat taagtttata gagaaaaaag
    20341 tgccacctgg agtggattta gtggttgtaa ttcttctatg tgcaccacta tctcgtctta
    20401 tagcatcaaa tgtagaccca ttagttaata gtacactact acaaattggg caagttttga
    20461 tagaagctac caacattagc cctataataa tgggaattat actaggaggt ctaataacag
    20521 tagttggaac gtctccactt agttcaatgg ctcttacatc tataattggt cttactggtc
    20581 ttcctatggc aataggagca ttaggtgctt ttggttcagc ttttatgaac tcaacactat
    20641 ttgcaaaatt gaaattaggt tctaaaaaag atattatatc tgttgctatt gaaccattaa
    20701 cccaatcaga cataatttca gctaatccaa tacctatata ttctactaat ttctttggag
    20761 gagccttttc tggtatcatt gtagccttga tgggtcttgt aaacatgaca ccaggtacag
    20821 ctacacctgt ggctggtttt gctataatgt ttgcttataa tccagttcaa caagttctta
    20881 taacagctgg tttatgtgct ttattcaatg taattgcagg atttttaggt tcaaaaatat
    20941 tcagtacctt taaagttctt actgctggtg aaatacgtgg tactgatgta gaagaagaaa
    21001 ttgcttaaaa aacaataaga tttataaatt tatatctcaa gtagtagagt tttatattgt
    21061 aggcaatttt attaattgca aacgttttat tttttattta tgtttatgat tattatgtgt
    21121 gttgaatatt tagataaatt tttatttatt atttttattt agatttttgt ttagtttttt
    21181 atttggttga tatattagga ataaaaatta gtatagttta ttactagtta gatggcataa
    21241 ctttttagat acataaaaaa ttttatatta attagatatt attaaaataa aagcgataca
    21301 tgaattttta aatgtccatg tatcgcttta tttttgccat aatcttaata actgattttt
    21361 aaagtttatt atcttaacaa agttcattat cttatataat atttaaatgc ataggcttct
    21421 ttaatttaac catctaaata tttaattaaa tattattata tgtaatataa ctaattttta
    21481 aatgaatgta taggagctgg aatccttcct cctctttgag taaataattc agatgaattt
    21541 gtatttatag gcattactgg tgctcgtcct aaaagtcctc caaattctac catatcacct
    21601 acatcacatc ctggggctgg tataattcta acggctgtag tcttattatt aatcatacct
    21661 attgctgcct catcagctat catggctcca agcgtacctg ctgtagtatt tcctggcaca
    21721 gctatcatat caagacctac agaacaaata gcagtcattg cttcaagctt atctatactt
    21781 aaagcacctt taataacagc atcaatcata cctgcatctt cagatactgg tataaacgct
    21841 ccactaagtc ctccaacatg tgaacatgcc attactccac cttttttaac agcatcattt
    21901 aaaagtgcta atgctgctgt agtcccatga gtaccaacaa cttcaagacc catttcctct
    21961 aatatatttg ctactgaatc accaatagca ggtgtaggag ctagtgataa gtctattatc
    22021 ccaaatggaa catccaatct actagaagct tcctttgcca caagttgtcc aactcttgta
    22081 attttaaatg cagtcttttt aactgtttct gaaacaacat caaaaggctc tccctttact
    22141 ttctctaaag ctctcttaac aacaccaggg ccacttacac caacatttat aattctatca
    22201 gcctcaccaa caccatggaa agctcctgcc ataaatggat tatcttctac tgcattacaa
    22261 aatactacta attttgcaca accaaaacct tttgcatctt ttgttaattc tgcagtttct
    22321 tttatgattt ctcccatttc tttcactgca tccatattta taccacatct tgtagaacct
    22381 acatttactg aagcacatac tttattagta cttgctagag cttttggaat tgacttaatt
    22441 agtatcttat caccttttgt atatcccttt tgaactaatg ctgagaatcc accaataaaa
    22501 tctataccta aatcctctgc agccttatcc aatgtctgtg caaactttac atagtcattt
    22561 tcatctgttg cacctgcaat aatggaaatt ggagttactg ataccctttt atttacaatt
    22621 gggataccaa attcacgctc tatatctttt ccaaccttca ccaaatcttt agcagaactc
    22681 ataatcttat tgtatatttt ttctctagct ttatctccat cagggtctat acaatctaat
    22741 aaagaaatcc ccatagttat agttcttata tccaactgtt cttcatctat catctttatt
    22801 gtttcaagta tatttcctac attcactatt atcacctccc cttactgtct actacagatt
    22861 atgcattgaa ttaaatattt cttctcgctg aatttttaca tccactgata atttcttacc
    22921 tctttcaacc aagtcctcaa ccgttttctc aaaagaattt aatgatttct ctaaatcaac
    22981 tatcataatc atagtaaaat aatcctgtaa tattttttgt gatatatcta ctatgttgat
    23041 attttgcttg tataattcat cactaattcc tgccactata cctggtttat cctttccaat
    23101 tactgttaaa attgctttca taataatatc ctcccttatt tttttataaa tcttatattt
    23161 ttacaaattg aactatgttt taacatatat ttcatttatt tgttagtaaa ccacttttta
    23221 tgtatatatt taatatattt taatacctat acattcattt gtcaattttt tttcaatatt
    23281 ctattatttt tatactattt agaaaattca tatattatat atgttttctc aacaataaat
    23341 acagttttca taataatgaa aggtattact tagcaatcgc atgattttct aaataatacc
    23401 tttctaaaaa ttattttttt aattttatga atttaattat actttttcta gtatcaggat
    23461 ttacaattaa tatagaacca atcataattg gtgttagtat acaaaataaa aaaataatat
    23521 ctttttttag attatattct ttagattcta atttataatt attatttatt attccatcat
    23581 aatcacttat atttgactta tttttatttg tatcttgatt tttgttagaa atactttccc
    23641 tataaggaaa agaatgttca ttggtaccaa atactaattt tgagcttaaa tcataattat
    23701 catcattttc tgtaattgaa tttttattgt aaaatccttt ttctttatca gaattatttt
    23761 ctttattacc gtctttaggt atatcatgag gatttttatt ttcattgcta tcagtacttg
    23821 attctacatc atctttagga gtatttggtt gtttctcatc agaattatca ttttcattat
    23881 tattattttc attattattg ttttgattgt tattactatc attattttca tttccattat
    23941 tcccatcttg attgttatca tcctcatctc tatccgggtc gtctctacct cctcctccac
    24001 ggtcaccatc aatatcatca ttttcccgtt catcatctgg tgtctcttgg ttgtctccgc
    24061 ctcccattat aaatcctggt ttaaaaacta tatttgaata cccttctttt aatcctccta
    24121 ccacttttac tctaaaacaa cgcaacttaa aatcttcaaa aaaaagtata gcttgatctc
    24181 taatatcctc ctgttcttca gatatccaat tgattccatc gcttgaatat tcaacaaaaa
    24241 ccttacttgc actatacggc atatcataaa ataaaacagc tacatatcca ttttttgtat
    24301 tttgaaattc cagttccaaa ttgtctattg gttttttctc tataacagat acattcaaaa
    24361 taggaactac atcatcattt attataattt tttctttatt taacatttct gttttaaact
    24421 ttcctgttat attaaaattt tctccctttt ccaacttttc ataataatca gtaaaatccc
    24481 attctacatc tatatcaagt cgattaccac tagatgtttc taataccata tatttgggaa
    24541 attttatatt ttctatttta tcatctttac ttacttttat ttcatcacta aatacaccaa
    24601 ttcccctatg acaacatttc acaatatcat agccagaatc ttcagctata gagggtataa
    24661 gctcattata atcatcaatt atataaactt tcttactttc tgatataatt gattgtgcca
    24721 acttattatt atcttttagt aacccacttt cattgttgct actatatgct tttattgaag
    24781 tttcttctat ctcaacatca cctttagaat aaacacctat agcatgttct ccattcactt
    24841 caatatcctt atttagtatt ctaatatcat tttcagtata aattcctatt gcatctttcc
    24901 catttgcctt tattttttca acagattcgt aggatgattt aatatgtaag tctcctcctt
    24961 cttcaacgta taaggctgtc ccatcagtag caattatgtt gtttatacca atacttatac
    25021 ttccaccatt ttctatatgt attactcctt cttttcctcc ttcacctatt atattcaatt
    25081 cattatcatc aataataaat ctcccatgat tttttatcaa tattttatat ttgttggtat
    25141 ctattgtaaa attactgtca taaggaatat aaaatctaaa ctcttcatct attaccatat
    25201 cacaagaaag agtataaact atttcttctt tattattttt attttcttga acccaccttt
    25261 caaaatcttc aagacaattt tcctcttgtc caaaaacttt atgtggaaaa cttataaaac
    25321 acaaaactat tatactcata aaaataaata tctcatactt tttcatctta cactcctaga
    25381 aattttttag ctttgaaaca atctgtcgaa acatacactt cacccactat aatttttcca
    25441 caattatcaa ttattgtcaa tttataaaag tatctttatt aattgttata aataaaaagc
    25501 tacttactaa agtaaacaga cgtttcactt taataagtag ctatattttt ataacaaaat
    25561 agttataata ttagaacttc cttcatttac aattttttgt aaagtctttt gcattttaac
    25621 tcttatctct tctggcatag tatataattt actttgtaat tgctctttta ctaagtcatg
    25681 tagtgattta ccaaacatat ttgattccca taaatctgct ggttgctctt caaatacttc
    25741 cataagatat tttatcatct cttcaccttg attttgattt ccaactattg gagaaacctc
    25801 tgtagatata tctgctttta taatatgaag tgatggtgca ttggctttta acttgatacc
    25861 atattgtttt ccttgtttca ttatttctgg ttcttccaga ctaagttctt ctaaggaagg
    25921 agctactact ccatatcctt ttatcttggc atctattaaa gcactttcta ttttatcata
    25981 ctcattttta actttagata gtctagttat cagactaagc agttgataat ctccttcaat
    26041 tttaaatcca cttttttctt caaggacatt atagaataaa tcttgctttg tctgtaaatc
    26101 aatatttata acaccttctc ctagctctac attatcaaca cctgtatctt ccaaaaactc
    26161 taactcagaa aatccttgta taataccttc tatatccctt attttaccta tatctataat
    26221 actttgtttt aatgttgtta ttatgctact ttttatccaa tgatttcttt caagaccttc
    26281 aacccatttt ggtaagttga ttcttatttc tgtaagtgga aaatcatata atacagcttc
    26341 cataacctcc tctatatctt cttcttccat ttcaaccaca ttcattggaa gaactggaac
    26401 ttcatacttt tcttccaatt cacttctaag catactcgtt tcctcacttt ttggacttaa
    26461 cgtatttaaa accactgcaa atggtttttt aagatttttc aattcttgta taactctctc
    26521 ttctggttct acatagcttt ttctgtcaat tccagtaact gaaccatctg tcaagacaac
    26581 tatccctatt gtagaatggt cttttataac ttttttagtt cctatctctg ctgccttttc
    26641 aaatgtcata gcttcttgtg accaaggagt ggatactaat ctttgttttc caccttcctc
    26701 atgccctaaa gctccttcaa ctatgtatcc aacacaatct accattctta cttttaaaga
    26761 tactgtgtct tttattttta tttctacacc atctgctggt acaaattttg gttctactgt
    26821 cattatcgtt ttacctgaac cactttgggg tatctcatct cttgttctat cctttttaaa
    26881 ttcattgtct atattaggta taaccaactt ttccataaat tttcttataa aagttgattt
    26941 tcctgttctt acaggtccaa ctactccaat atatatatcc ccctgagtcc ttttggatat
    27001 atcttcgtat atgttattat tcatattatt cctcctatac atctaatctt attaaattat
    27061 atttagagtt aagggttaat attcttaaaa tagaaaaata aagaccagca atattaattt
    27121 aatttatata tagaaatttg taaatttcaa tgtaaattaa attaatattg ctggtccaaa
    27181 tagtagtgta ttatattaac tgactttagt agtattttca tttgaattat tattcatctc
    27241 aataagttct ttacgtcttt cttttgtcat gttcatccat ataaatgtaa acaccaatcc
    27301 aattatggct actatagtaa gaactatgaa gtagtaccta tatccagtta cacccggaaa
    27361 tgcatccaat atcttccctg ctgctaaagg acaaagtact tctggaagat atcctaacgt
    27421 agcaactatt cctatagcag ttcctgatat tgataatgaa taattacctt cttcaagtaa
    27481 cgaatagtgt aaaccttgaa ttgcatacat agatacatat attgcaacac atccaatcaa
    27541 tagtatataa atcatagatg attttgttgg tgtaaatatt acacctaaaa gacctgcaat
    27601 cataagtata aatccataag atataatctt tgatgaacca actttatctc caagtaatcc
    27661 agaagcagct gatgctactg gtctacaata ctgagctaat attgagattg cagatgcaaa
    27721 caccacagta gctccaaatg cttcagttga ataaggcgta aaataataaa atgacatatt
    27781 agctgaatat gaacaaaaca ttattattgt tattatccat gtatgaggca tttttattac
    27841 tgcaaaaaag gcttctttat caaattttgc tgatacctct ttttcattat cctttaattt
    27901 gaaaaatact aatactccaa ctattacatt tattgctgag tataatacta taatagctgt
    27961 aagaccagat tcatcactta cttttgatga aatataccca aatagtatca atactagaga
    28021 tagatgaatt gcattggtaa ttccacgacc actttccata aatccaaaag cttttccttg
    28081 ttcattttca gatgctaaca ttctaacagc ttttacaaga gctggccaaa aagtaagtat
    28141 tgttgttatt ccccataagg catggattaa aaacacaaca atatatggag gataaagtgt
    28201 taatacaaga ccagatattc ctgtaataat taaagaacct gaaagcaatt ttctggctga
    28261 aatacggtct gctaaaaaac caccaaaaag gtatgatacc attgcaagta gaccataaat
    28321 gcttcctaag cttcccattt gtgtatttgt aagattaaat gcttgtgcaa aagtatcata
    28381 ataataattc tttaaatatg gtaaagcata tataaatgct cctgctacaa agagtattat
    28441 caagactttg aaatttttcc aaatgcttgg tttatttact tcaactgaca tacttcctcc
    28501 ttatgtaaat acctgtaaat tttcataata attaattatt gcttatttta ttgtttattc
    28561 aatatttagg aatatttatt aatatattag gttaatctat caataattta tggtgagtta
    28621 tgagctaaaa gtaaactctt ttagctcacc ataataatta tatttttatt tatactaaca
    28681 tccagagtta ttagatatct ttttttcata gttcttccat agcattaaac ctgttattat
    28741 aacaaaaaga cctcctccta tcatttcaat ctcatagatt atattatctt ttaaagtctc
    28801 cataactggt gccgttgaga aaagtatgcc aactacagtt actacaagta ccattctggc
    28861 aatattgata caaactgaat cactttttgc aattgaatat ggtctttctt catttggtct
    28921 tgtctttcta agtctaatat aagatgtaaa aagcaagaca tatggaaata atgctgttaa
    28981 tgctgtcata gtaacaagaa cattgtatat attatctact gatggtaata agtttgttcc
    29041 tacaagaagt agactcacta ttatagcctg aactattact gcatttgatg gtatattgta
    29101 tttatttgta acagtcaatt gcttaggaaa tacaccttct cttacatttc caaaaagcat
    29161 ctttactgga cctgctatat aaagtattaa tgctcctagt actgataaag ttattccaaa
    29221 tgctactatt cttataaacc aacttcctat acctaaatct tgtgcaactt tagctaatgc
    29281 atctagtatc cctgtagatg ctgcaatttt atctggagga agtatcattg ttattgctac
    29341 tgaacctaag atatagattc ctcctattaa aacagccaca gttaatatag ctttaggaaa
    29401 gtttttctta gcattatcca tttcggttat gaaattagca gtcgtttcag ctcctgataa
    29461 tgcaaatatt atagcagata tagaaactaa tgaattggca tctatttttg gtattatatt
    29521 ttggattgta tatatcgatg ctgatggagc ttttttgaga ataactacag acataaatgc
    29581 catcactata agtaatatag caggaattgt agaacctaat gctcctgtat tcgtaaaaaa
    29641 ttttccaaat gccatcccac gagtacttac taaggacaac agccaaaata ttatgagtga
    29701 aagtgctaaa ataaacatct tattgtttga taaatctgga tttccaagca tatatgcaat
    29761 atttatcgct aaaaaagtca agaaagaaga ataccaaaat atctttgatg tccaatttag
    29821 ccatgacacc ataaatcccc acttctctcc ataagcttgt ttaacccatt ctccaagtcc
    29881 accatctttt ggatatgttg cagccaactc tgcacatata agtgatgcag gaacaaagaa
    29941 tataaaagca aacaataacc aaactggtat agaaccaaga cccaatccaa aactagaggc
    30001 agtagattta gctatccatc taatcccaaa tagtgctgat atattcataa atactaaatc
    30061 ccaaaatcca attttctttt tcactgtaat tcctccaatt tcaaatttat tcagactcat
    30121 acacaatgta ttgacttaaa tatcaagtat aagttcttca acacttcttg gataattagt
    30181 tataattgta gcaccattct tacctactat tgctgtatct gagtgtctaa atcctccaac
    30241 tccaggtata tatatccctg gctccataga aaataccatt ccttcttcta atattaattc
    30301 attgtcaaat cttaaatatg gctcttcatg ttctgataaa cctaaaccat gaccaattct
    30361 atgatttgaa tataactcta gaccatactt tgcaacaaca gctcttgctg cttcatccac
    30421 cattcttgct ggtataccag cttttattgt atctaatcca gcttgttgag cctctactgc
    30481 aatcttaaac acttcttttt gtctttctgt tggtttgcct ataataaaag ttctttcatt
    30541 ttctgctcta tagttttcat accaaacctg tctactatgt attactatat ctcctctttg
    30601 aagtattcta gtattggaat ctaaatgagg ttgtgctgtt ctatcaatcc ctgaacaagt
    30661 ccagtttgca aatcctatat atgtatcagg ataattttca gaaacatatt ttagtaaagc
    30721 attatcccct gcaacgtcaa actccaattc actcatccca actctaacat tttctaaaga
    30781 cccttttatt cctatatcag ataggtaacc tgctatcttc aaaaattcta tttcttttgc
    30841 atcttttaca tatctcattt caaatatttt acttccaaca tctttgatag caaatgactt
    30901 atcagttata tactctgaaa agcttgcaga tactatatct ttttctattc caacagttgt
    30961 tcctttaggg tatttattta aaattatatc taagtaatgt ttatgtgata ttccatgttc
    31021 tttcatttct ggtatttcat aatacacata tacattatca acttttgcaa cttctttagc
    31081 atgtaattct tctaatccag gtactattaa ttctatttta tcttgagtta ctactgttac
    31141 aattggtcta gaataagtta ttgctttaaa tccactaata taaaattgat tgtctggttc
    31201 aaatattaaa gcaatttcaa tgcttttttc attcatgtac tttctcaatc tttctagtct
    31261 catattattt gacataatgc acctctttct taatattcag ataatttatt caatacaaca
    31321 aggatgaata tattatttta aaattcttaa tatttttagt acttgtcgta tttgtatgta
    31381 aattaatttt atttgtgatt attttatcat aatcatgatt attttgtcaa tcatgatttt
    31441 attttaaaaa attttttata ttctagtgat tttaaattat ctaaaatata acgagtatac
    31501 attgtatttt gtaatattat tcttgattta tggtaagttt aatgataaaa tcacgattat
    31561 ataaactata ttgattattt gtaggtgaat aaaatgacaa ataaagaatt acaaaagaaa
    31621 aggatattga tgtatttcat agaagctgct caaaatatta tggaaaacga aggtatagaa
    31681 aatattacac ttcgtaaggt tgcagatatg gctggctata atagttcaac tctatataaa
    31741 tactttaaaa atttagacca tttaatatca tttgcatcta taaaatattt taaagattat
    31801 aacttgaata tttcaagatg tatagaaaat gtcaatgatg aatataagaa atatataatt
    31861 atgtggaaat tattttgtaa gcattctttt gataatgctc aagcttttta ccaggtattt
    31921 tttaacttgt ctagtgatga acttagctat ataacaaaac aatattatga tatgtttcca
    31981 gaagatttag gtattcatga tagtgacata tctttaatga ttacaggaga aagtataaag
    32041 gaaagaaata agatactatt aaacaatctt gtagatactg gatatatacc agctaaagat
    32101 ttagacataa tcaatgatat aattatttct ttttatcaaa atctattatt cttaaaaaag
    32161 aacacaggaa aaaattctga tgatgatgaa ttaactatga aaatgatttc ttctattgaa
    32221 tacataataa aacatgctaa ataaaattaa aatatggctg tctcaaaata gagataagcc
    32281 ttttttattg ttgaaataat aaaaatatat ttaatttcat ataaaaaaga gtgcctcgta
    32341 aactaaaaag ttcattttga gacaccccta aaataaattt attatttatt atacaatagt
    32401 ttatatatca tcacctaaaa ctacttcttc catttcatgc tttttacttc tcatcattag
    32461 ttctattcca acttctttag gatttgaacc tttctttatt acagaatata tagcattagt
    32521 tataggcata tctatatcta atttttcagc aacatcatgt gctacttcag tagcagttat
    32581 gccttctaca accatcttta cttcttttaa agtatcttct aaactcatcc ctttacctat
    32641 gagtatacca gctcttctat ttctactatg catacttgta caagtaacta ttaaatctcc
    32701 aatacctgaa agacctgcaa aggtagacat attagctccc atagcaattc caagtctgct
    32761 catttcacta atacctcttg tcataagggc agcttttgca ttatcaccat accctaatcc
    32821 gtcacatatc ccagctccaa atgctataat attttttaat gctcctccaa gttctactcc
    32881 aactatgtct ggattcgtat aaactctaag tttagggctc ataaataaat cttgtatcat
    32941 ctgtgctatt tttaaatctt tagaagcaac tactacggta gtaggaatat cccttgctac
    33001 ttcttcagca tgagatggcc cagatagtat tacatatgga ttttgtggta attcttcttc
    33061 acagacttga gataatctaa gcccagtccc tttttcaaga cctttagcta cattaacaat
    33121 aacttgtcct tcttttataa atggttttat tttttggcaa gtacttctta cagcctgtga
    33181 tggaactgct aaaactatta ccttacaatc ttttatagtt ttttctatat cagtacttat
    33241 agttatatta tttggaaata atactcctgg taaatagtct gtattttctt tagttctgtt
    33301 tattttttta gcttgttcct cttttcgagt ccacatgctc acatcattac ctttttttgc
    33361 aagccctaaa gctaatgcac ttccccagct tccagtacct aatacacata ctttctccat
    33421 gtttaacacc acctgagtat aatatattta ctattctttc ttttgaccaa tttttctctc
    33481 tgtcccattt aataatcgct ttatatttgc tctgtgatta tatattactg atgcagttaa
    33541 gaacagagct actattaaac cagctttatt ttttaccata atcataaata ttggtgaaca
    33601 tcctattcct acaacagaac ccaatgaaac atactttgtt atagctacca ccaatataaa
    33661 tactgctaga cacattagtg ttattactgg atttacagct agcattgccc ctagtgaagt
    33721 tgcaacacct ttgcctcctc taaatcctaa aaccgctggc caattatgac ctgctacaac
    33781 acatataact gccagatatc cagctaaaag agtatctatt ccaaccaatc ttgctgcaaa
    33841 ttctgatatt aaaacagcca ttacaccttt aagaacatca cctaaaaatg tcattgctcc
    33901 tgctcttttt ccaagtgtcc taagtacatt tgtcgaacct gcattaccag aaccttgagt
    33961 ccttatatca accccagcaa ttcgctttgc aactatgtat gaggtagata tatttcctaa
    34021 aagatatgca actacagcaa taattatata actaaatatc tccactgaat ttcccccctt
    34081 tagttatatt ttaagatatt tattttttat ttttttgtct atactcaaac tttatggaag
    34141 ttccttcaaa tccaaaattt tctcttatct tattctcaag gtatctttga tatgagaagt
    34201 gagttaaatc cttatcattt ataaacaatg taattttagg aggtctaatg tcagtttgag
    34261 tcccatagta aatttttaat cttctacctt tgtcagatgg tggttgattt aacattacag
    34321 cttctccaat tacttcattc agtgctgaag ttgatattct cttagaatgt tcatttgaca
    34381 catattcaac tgtatctagt atcttgttca ttctttgatt agtttttgca gaaacaaata
    34441 cgattggagc atacatcata aatggaaatt tttcttttat atcttttgtg taattgctca
    34501 tagtcttatt atctttctct attaaatccc atttattgat tacaaatatg catccttttc
    34561 cttcatcatg tgctatacct gcaacctttg tatcttgttc tgttacacct tctaaggcat
    34621 ctattactat caatactaca tctgctctat ctacagcact catagccctt attacactgt
    34681 atttttctat tgtctcatat attttacttt ttcttctaag ccctgctgta tctattagaa
    34741 gaaatttctg tccatttttt tcaaaataag tatcaattgc gtctctagta gttcctgcaa
    34801 ttggacttac aattactctt tcttctccaa gtatcttatt gagtatagaa ctttttcctg
    34861 catttggttt acctgttata gctactctta ttatatcttc ttcatactct gtatctaatc
    34921 ctgctggaaa attttcaact atctcatcta ataaatctcc aaatcccata ctattggctc
    34981 ctgaaactgc aaaaggcgtt ccaaatccca actcataaaa atcgtatata ttatcaaatt
    35041 gactttgact atcaatctta ttaaccacta agattactgg tttttttgtc tttctaagca
    35101 attgtgcaat ttctttatca gcagctgtta ttccagcttt accatcaact ataaaaagta
    35161 ttacatgtga catgtccatt gcaagcatgg cttgatttct catttgagat aatattatat
    35221 cttcgctatc aggttcaatt cctcctgtat ccactaatgt aaaatattta tctaaccatt
    35281 ctacttcagc aaatattcta tctcttgtaa ctccaggtgt attttcaact attgatatcc
    35341 tttttcctgc aaatttatta aatattgtag acttaccaac gtttggtctc ccaactacag
    35401 ctacaactgg cctacttata ctcattttat ttctccttcc atcttttgtt ttctatttta
    35461 aaattttatc cacaaaatct tttccttcat tcaaacaagg gataattttt attctcataa
    35521 gttcttctaa ttgatttaat tcaatattat ctaagaaaat ttcttcatct gcttttagca
    35581 tacttcttgt tatataaaga gcttctccta attctttatc ttcaagttgt tcttttaaat
    35641 ccttagctgt taaaagacct gatacagtta ttgtctctcc aaaaaacttg tttttgattt
    35701 catatacatt tacttgaaga tttttaaact tgtccatcat agcatctgcc atactctgta
    35761 taaattcata tgcagaatga ccagtagcta ttgatacttt cttctctctt tttagaatct
    35821 tctcaggcaa tatatttaga tactcttcaa tctctgtttt taacttacgt atcataccta
    35881 caccatcttc aaactgtaaa aaaccttcat attcttcata tccaggcaat tcactattag
    35941 atagtatata aaattcatct gataaaaatg caaatcgagt acctaatttt tcaagatatt
    36001 tctgttgtat ttgatgtatt tgctctatag ttttacttgc gctcttatca ttaaatatat
    36061 ttaattctac tagattttct ctatgctttg taatcccaac tggaactatc gcaacactgt
    36121 ttacatacgg ataaagttga gctagttctt ttattgttct atccaattcc tttccatcat
    36181 ttatacctgg acataaaaca atttgacagt tcatttctat atgagcatct gccaatctct
    36241 tcattatacc atataatttt cctgcaaatt tattgcttat cattttttgt cttaactctg
    36301 gattagttgt atgcacagat atatttatag gacttattct atattttata atattattta
    36361 tatcttcttc actcatattt gtaagtgtga caaaatttcc ttgtaaaaaa gataatctcg
    36421 aatcatcatc tttaaaataa agagtttctc tcataccttc tggcaattgg tctataaaac
    36481 aaaacataca cttatttcta cagcttttag cttggtcaat tatcggattt gtaaattcaa
    36541 cacccaaatc ttcatcatag tctttttcta tctcgtatat gtagacttcg ccatcttttt
    36601 tttgtatttc tacatctaaa tattcatcac ttagtaagaa tctatactct attatatcat
    36661 gtattggctg ttcattcaca gatataagta aatctcctac ctctataccc atttcttctg
    36721 caatactatc tttataaacc ttacttataa tattatttac tttttttaca tttacttcca
    36781 atattttcac cactcttttg tattcatcaa tgcttattat aatgtatttt aatatgcaat
    36841 ttatttattt attatatttt atgatagcat ttttaagcat ttcatgtcat aataacacat
    36901 tttaattcta atagtcaata taagtaaata gctataaaat agattagaac aaataatatt
    36961 caaatttaag tttcttaaaa atttaaatat tatttgttct taaaaaaatt ttataaattt
    37021 aatgttttac tatgattaac gtcccatttg tcatatcatg aaccattcca cctacacact
    37081 ttgacatcaa caatgcctta ttttgtaagt ctttctcatc atttgcataa aatattggac
    37141 aacctccacc atttttcata ttcttatcaa gtgtaactat agctagggta tattcattta
    37201 aacctatatc cattcccatc tcatgcactt cctttctttc ctattttata attttttagt
    37261 gataagtttt ttcctttaga gcttgaaagt attgggcatg actttacagc ttccattact
    37321 ttttccacat tcttatctac tggtaaataa gcaatcatta tactttcatc ctctttattt
    37381 cttctaggta atggtacgaa tgaaggttct ccataatctc catataaacc taaccttgaa
    37441 tatatattgt atactattgc ttgtctttga ccggagtcaa ataatattcc tgcattagca
    37501 taatccttat ttttaggaat tatttgtatt cctacacctc tattaatata tacttctcta
    37561 tcgcttttta gacctatatt tgttatacct tttaaatctc ccacctttag tatagattcg
    37621 tccacaaaac taatttcagc aggcattaca tcagctatgt ctccaatact ttttctagta
    37681 agaagttttt ttaatataaa ggctaacact aatccacaaa ttgaacttat taccaaactc
    37741 atcccttcac ttattttcgt ttctgcaagt attacataat acaatcctat tgttaaaaaa
    37801 gatgtaacta tacacatata atttcttact tcataggttc tagctatctc ttctatgaat
    37861 gcagctcctc tctttacaag ttgaacttcc tctaaatttt gcaatgtatt tcttctattt
    37921 gctctcactt gtctaaattg ttctgctgct agagataaaa aagttataga tgtataagaa
    37981 cgatttataa gagctggaac caataatgct cctaatgaag aagcgacgaa tgctaatata
    38041 agttgagata gtaaaacatt tggttgcgtt ggatactgtt tttggtctaa attcaacatt
    38101 ataattctag atgttatacc aataataaca gcaacaaaaa atactctatc cattaaatca
    38161 ctcctaaaat atttaatttg aaattttaca tgtaaatcta caaagtcttt ctagaaaaat
    38221 cactctgctt tccttttgat gtttctatga taggtgtact tttcactaca tctatcatga
    38281 catctatatc tttgagtatt ggcatatatg gtataaccac agtacttttt tctaaattgg
    38341 tcttagatat agcaacaata tcaacctcat ctacatctct atctatcccc atatgaataa
    38401 atagattatg tattatagct tgtctttgcc ctatatcatt tactattcca aatgcaccta
    38461 aatctcttgg tataacttct atggccagac attcatttct atacttttct cttgtacttt
    38521 ctagacctat gttagttatt attacaccat ttaccattaa aataggtcct tcaaaactta
    38581 tttttgcagg aactatatct gctatatctg ctatactgtt ccttcttaaa aatcttctaa
    38641 aaatcaaacc aacaatagct cctgacacaa tagctaggat tgtgcaataa aaaaagctaa
    38701 ggccatactt tcttgcaaaa acgatataaa ctatcgaaga taccagtgca gaaaaaagac
    38761 ttatataact tctagattca tacgtagatg ctatttcttc aacgtaagcg tctccttttg
    38821 gtactaattc ttcattatcg atattcttta gtgttattct ttcttgttct gcaagacctt
    38881 gaaactgttg tattgctact gcaaaaaatg tcaaggctgc aaactcctta tctataagtg
    38941 caggtaatgc tatagcacct aacgaagctg aaagcccaga tataattatc tgttctaaat
    39001 aatcttgtgg tcttgatggg tattgtttgt ctgtaactct taaaactaat cctctacata
    39061 atattcctac aactaatgca actataaaag agtgtctaaa taaatttgca ttcaataaac
    39121 tttcttccat tttctcagct ccttctctta tatagtttgt gcaaaaaaca aaaaaaattc
    39181 ccttctattt aaggaaattt ttttgtaata ttgtaactat aaattcgcta ccaatgccaa
    39241 gttcactttt tacttttata catccattta gtgatttgac tatatgcttt gttatagcca
    39301 atcctaaacc cgttcctcct acatccctac ttcttgcttt atctacccta taaaatcgtt
    39361 caaatatgcg ttctacatct tcttttggta tccctacacc attgtctata actttaatta
    39421 cgattttttc ttcatctttt aacactacaa cttgtacaat cccattatct tgggtatact
    39481 ttatagcatt atcaactagg tttaagaaca cttgctttat atagtcttta ttggatagta
    39541 tacttattga tttatcatca catttatata aaacttctat atttttttca ctagctgaat
    39601 gttgagttat ttcatatacc tctttaaata catcatatac tacaacattt tccataagaa
    39661 gagtatcttt attttctaca aatgataaca gcaatatatc atcaatcaac ctttttaatc
    39721 tatctgattc gctttctatt atttctaaga atctatttct agtattcaca tctatatttt
    39781 catttgactt tagtgtttca acaaacccac ttatagatgt aagtggtgtt ttaagttcat
    39841 gacttacatt tgcaacaaaa tcacttctca tattttcaag tttaactttt ttagtaatat
    39901 cttctatatt tactatcgaa cctattatta cgttgttagt attctgaaga taaactgggt
    39961 ctacttttat cttatatacg atatcatctt tagtagtaat attagcagtt tcattatctt
    40021 tagaaccaat aaattgaagt atttgtttta atatttcttc ttcttttatt acaacattaa
    40081 tattatgacc ttcaactaat tgatttggtt cactctttat catttctttt gcttcatcat
    40141 ttatcagaag tatatttcca tttacatcta tagccaaaat tccatgagat atactcttta
    40201 atatagacct taactgtaaa tgtttatact gtacttcttc taaggtttta tccatattct
    40261 ttatcatatg attaaaattt ctagctaatt cgccaagttc tcctttggct gatatgttaa
    40321 gcctagcatg atattcatta ttacttactt tttttgagac gtatataaac tcttttaaat
    40381 atttccttaa tgttattgtg tatcttacag ctaatataac aatggctatg gacaacataa
    40441 caataaaaaa atatatacta tttaaatctt ccacaagata acactcctaa aatataacct
    40501 ttttaatcta ttttgtatcc tacacctctt atagtctcta tatatttttc cgatttatct
    40561 tcatcttcta ttttttttct taaatatctt atatgaacat ctactgttct agtttctcca
    40621 tagtattcat acccccatat tttatccaaa agataatttc ttgaaagtac ttttccttta
    40681 ttttgaatta ataattttaa caattcaaat tccttaagag ttaactctat cttttcagag
    40741 cctttggtaa cttcatgttt tgataaatct agttttaaat tacctgtagt aagtatattg
    40801 ttttcttcac ctaagctagt caaattatat ctccttaaaa cagaactaat cctagctaac
    40861 aactctttta tactaaatgg cttagttata tagtcatcag cacctatttc aagcccttca
    40921 accttgtcat tttccatatt tttagcagta agcattataa caggaatatt ttttaagtcc
    40981 ttatcacttc ttatttttct caaaacttct attccactta tatttggtaa catccaatct
    41041 aaaagtatta aatctggttt aatttcctta gcctttataa atccgtcaaa tccatcatat
    41101 gaataactaa cttcgtaatt tgacacctcc aaattgaatt ttaatagctc aactatatgc
    41161 atttcatcgt ctataacaag cactttagta ttcattaaaa agctcctctc tattttatct
    41221 gtagtaccgt tcctattcgt tctgatgcct tattatgttt tctataagag tggaatttat
    41281 ctgctctaca actagtgcat aaatttaaat ttattatatt ttctttttta actccactac
    41341 atctaagcat atactcatta attttccata aatctaaata gtaacttccc tcttttatta
    41401 tatagaactt ttcatcatta tttgtaagaa ttgtgttaaa tttttctact aaatcttcag
    41461 acacttcata acaacatggt ccaattgatg gcccaattat acatactaaa tcttcaggaa
    41521 ctgttttata gcattcagac attaatttta ttgttttatg acctatatta ctaaaagtcc
    41581 ctctccaacc tgcatgagcc agtcctatgg ctttattttt agcatctata attgatatag
    41641 gtacacagtc tgctgtaaac agtaaaagtg gtactttttc caagtttgtt ataagtgcat
    41701 ctccatctct tcttttccct atagtatctt tattgactat attaactata tctgaatgta
    41761 tttgagaatt actagttaga ttttcaaatg tcaaatcaca ttctttacat acttttaaca
    41821 tatcttctct attttttgca tctatattct tacatgttat aactagattt acagaattta
    41881 atttttcatc aagttcttca caattaccac ttaaattaac atactcttta atatcttgta
    41941 cattttttat atttatataa tctttcatca tttgtctcct ttttctatca gtatactttt
    42001 aagttcattt acaaaagtat ttatatcttt aaattgtcta tacacagaag caaatcttac
    42061 ataggcaacc tcatctaact ctttcaattt atccattacc atctcaccga tttttttggt
    42121 ttcaatttct tctataaaac atttatttat ttcattttca atatgtacaa caatactttc
    42181 aatctcgtca atagaaacag gtcttttttc acatgctttt agcaatccat attttatctt
    42241 ttctctatca aaatattctc tactattatc ctttttaatg accattaaag gagttgtttc
    42301 tattttctca tacgtagtaa acctcttttt acatgattca cactcacgtc ttcttctgat
    42361 agattttaaa tctgtatgtc tagaatctat tacctttgat tctttataat tacaataagg
    42421 acattgcatc tatattcctc ctttgtttaa ctatatctca aactcatcta agcttaattc
    42481 tgaacctata tttactatta ttgtatcaca acctatttta agtatatcat tccaaaatat
    42541 aacttcttca tcccctcctc ttgaaaaaaa acttctactt ccatctccaa aaatggtaaa
    42601 tgagactacc ttaccttcgt gaatatccat gtctatgtct attataaacc ccatcctttt
    42661 tccatttttt acatttataa tttctttttc cattatatca gaaactctaa tcatattgta
    42721 ctcacccttt ctttaaaaat aaatatgtat cgaagtaaaa aaaaatgacc tatataggtc
    42781 atttaaatta aaataatgtt tacagtccat ggattactta tacatatttt ctcatatttt
    42841 ttaaagcatt tttttcaatt cttgatactt gtgcttgaga tataccgatt tcatcagcaa
    42901 cttctatctg agttcttcct ttgtaaaacc ttaaatctaa taccaacttt tctctactat
    42961 ttaatttctt aatagcttct ttaagtgata tttcttgcaa ccaattttca tcagtatctt
    43021 ttttatcttg aacctgatcc ataacgaata ttgcatctcc attgtcttga tatactgggt
    43081 caaacagaga tattgggtct tgtatggcat caagtgccat tacaactgat tctacttcta
    43141 attctaattc ctttgctatt tctgatactg taggttcttt agaatttgtt ctaattaatc
    43201 tttctctaac ttgtagtgcc ttatatgcta tatcttttaa tgacctactt actctaattg
    43261 ggttattgtc tcttagatac cttctaattt ctcctataat cataggaaca gcataagttg
    43321 aaaaccttac attttggctt aaatcaaagt tatctatagc ttttataaga ccaatacaac
    43381 ctatttgaaa taaatcgtct atattttctc ctctgttgtt aaactttttt attacactca
    43441 agactaatct taaattccct cttacaaact gttgtctggc ttcttcatca ccatttttta
    43501 tttgtaataa aagttccttc atttgcttat ttttaagaac tggaagttct gatgtattaa
    43561 caccacatat ttcaacctta ttaacttgca tatattttca gtcctctctc aaaagtattc
    43621 atctattgaa attatttaca tttccaattt ttttatactt tttaagaaga attaatttag
    43681 cattatacaa attttttcat ttctttttgc aaccttgaga ttattttctt ttcaagtcta
    43741 gatatgtagg actgtgatat tccaagcatt ccagcaactt ctttttgtgt tttttcaata
    43801 cctttatcaa taagaccaaa tcttaattcc ataatttgct tttctctgtc acttaatctg
    43861 tcaagtgcca taaccaacaa atctctatct atttcttctt caattatttt gtatatttca
    43921 tcattttctg tacccaatac atcagataat aaaagttcgt ttccatctaa atctatattt
    43981 aaaggttcat caaatgatac ttctgttttc tttttattat tttttcttaa gtacattaat
    44041 atttcatttt ctatacatct cgaagcataa gttgccaatt ttatattttt attcagttta
    44101 aaagtattaa ctgcttttat caaacctata gttcctattg aaatcaaatc ttctacatct
    44161 atacctgtat tttcaaattt tctcgatatg tagactacta atctaagatt tctttctatt
    44221 aaaattgact ttacactttc atctgtttct agcttttgta aaagctccat ttcttcttct
    44281 ggtttcaatg gaggaggaag tatatttgcc cctcccatat agtatattcc ctttggcttt
    44341 attattttta atttaatacc taacatagta ataaagctta ttattctttc tttcaatcgt
    44401 aacattcctt gtccccctta aattttcacc taaaatccag gcaatatatt tggattcatt
    44461 attgctccat attctctatc attaaaattt gaaataccaa gtattatatt tcctatcttt
    44521 tgctcatcta cttctatata gtcagctttt aagcctatta ttatgcttgt cttattactt
    44581 ccagcatgtt tataaggtat tattctaact ctacctgaag ttttatcatc taaacttcct
    44641 ataatttctt gtgctttctt catatctata tcttcataat taatatttaa tagtttttct
    44701 ggaataaatc cttctaacac actagactta actattatta catcactttg acttattggg
    44761 tcttttaaca aattaccact atctactaaa gccttacagc aaaaactttt ttctagtaag
    44821 tttatattta tagtctttgt aagctcctta atgtacttaa gcattttcaa atctttataa
    44881 atgtatttta ataattcaca actcacataa gtacatgcaa ttaagaaaga tatttttaag
    44941 tgacttattc ctgtaaaata aattataaaa taagtgcttc cagaaataaa aatgtttact
    45001 agataaaaaa ctaacgctac atgaacataa tcttttttgc tcttacttct aaatgaaatt
    45061 aaagttatta tactcatgat tattatttta aatggtacag taaatagtat attcattgat
    45121 ggatacaaat aagcaacaga ataggcacct cctaaactag cccccaataa cttatttttt
    45181 ttaggattat atcttttagt aagaatagaa gtacaactta taataatata atttattact
    45241 aggttttcta taacatagta ctcaatatac accatgtatc cccccttaaa acctttaaac
    45301 atattataag atagtatgta caaaatttta tgtcactttt gatggtcgaa tccaaaacaa
    45361 attctattta aaaagaacaa tgatatatgt cttatacttt atgtcgtcaa aagatatttt
    45421 tttaatacca aacaaataga cttttttgta gaatccaata tatctaggta gaagttattc
    45481 actctacttt tggtatattt acaaaaaaag actacataat ttaataatat atcaagtaaa
    45541 tcttttactt atataaaatc aaattatata gtctgtaaat tcaaatataa attattgtgc
    45601 tagtaatcca tttgcatatt ttgcagattc atttagtgct tgttctggag ttatgtctcc
    45661 agctatcatc atttgaagtt gtttccataa atattcatat atctctactc catgaggtcc
    45721 aactgtcaat ggtctataca tatgtttatc tcttgtcacc atttcttcaa atcttgggtc
    45781 tccttggtat ttttcacctt tagcaactgg agctctaggt atttctttgt ggaaagcttc
    45841 cattgattct ttgcttagca tatactcaag aagtttaaat ccaagttctt tatttttaca
    45901 tgctgacatt aatgttaaat catctactga agcaaaactt ccaactgtct tatcttctaa
    45961 tgatgttaca tatccccagt ttaaatccgg gaatgattta tcaaaagtac ttgtagcagc
    46021 agaggatagc attatagtaa atgcagcttt tcctggtcca aatacacttt caatcatttc
    46081 attactatct tttgataaag catcttctgg aatatacttt ttcatatcat ttataaagtt
    46141 tgcagctttc aagccttctg cattattaaa tttaactgat tttaaatcat cattatatat
    46201 atctccacca gcttgccata aatacggata ccagttccag tttaagcttc caaatacttt
    46261 agaaccccaa ccttgtgcaa gaccccactg gtcgattttt ccatctccat cagtatcttt
    46321 tgttgctttt tcacagattc ttttaaaatc atcccatgtt tttggaggtt tttctcctaa
    46381 tttttctagt atatctttat tgtagtacaa tacgcctgga ttagcagctt ctataggtaa
    46441 accataaata ccacccatca tttttgcatc atctaagtat agataattat ctgaagttcc
    46501 tgatttttct aaataaggtg ttaaatcttc taccgcaccc atttctataa attgaggaaa
    46561 catctctgca tacatgtatc ctatatctgg accttcacct gcacttattg ctgttgcata
    46621 tttttctgcg tagttatccc atggtactat ctgaaattca atttcacagt tattttcttt
    46681 ttcaaatttt tcaaatatcg gcttccatgc atctgcatca tggtctgtta atggtgcaga
    46741 ccatacaact aatttttctt taccctcttt gcctttagaa tcttcttttt ttgaacatcc
    46801 tgcaagaatt gatactgata gaatccctac cataactaaa gaaagaacct tttttagttt
    46861 aatcatgctt aatccccttt cagactttaa tttgtctttt tcctcaaatg tttacattta
    46921 attcagattt aatattaaca aataagatta ctcttgtcta atcataaaaa actatactaa
    46981 ctcctataac tatatttttt ttctatacct attagattta attcatacta aaaacttact
    47041 ttttaaattt tatcaatatt taaaaatttt tttaagtcta gccacaaact aactatctaa
    47101 attgagcaaa ataaaaagaa gtctattgac ttctttataa gcttacatat tatcttcttc
    47161 ttcttaggaa tgtaggtatc tccatgctct catcatcatc ttcttcaatt atacttgcct
    47221 ttttaggagg ctctattttt tcctcagcaa ttacttcttc ttcaatttct tttacagctt
    47281 gttttactgt tgtatttaat gaagaacgta tgcttgattt aggtttagta tctaaatcta
    47341 aggcaccatt ttgtaatcct tcaaatcctg tcgcgattac tgtaatcatt atttcatcac
    47401 ctaaatcttc ttttatagaa gctccaaata taacatttgc ttctgggtca caggattcca
    47461 taactaaagt tgatgcctca ttaacttcaa ataatcctaa gttaggacca cctgtaacat
    47521 taagaagtac tcctttagct ccttgtattg atgtttctag aagtggagat tgaatagctt
    47581 gtcttgcagc atcaattgct ctagtttcac cactagcact acctataccc atatgagcaa
    47641 gtcccttgtc tttcattata gtagtaacat ctgcaaagtc caagtttatt aacccttcaa
    47701 ctgctataag gtctgaaatt gattgtatac cttgttttaa tacatcatct gcaactgcaa
    47761 aagcatctaa cattgatgta tttttttgta ctatctgtaa aagtctatca tttggtatcg
    47821 ttataagagt atctactttt gatttaagtt ctgctattcc accttcagcg ttcttcattc
    47881 ttatcttacc ttcaaatgca aaaggtttgg taactacacc tactgtaagt atccccattt
    47941 cttttgccaa gcctgcaacc actggagcag ctcctgtacc agtaccaccg cccattccgg
    48001 ctgttacaaa gaccatatca gctccttgaa gtaactttac tatttcatct ttactctcct
    48061 cagcagctct tttccctact tctggatttg ctcctgctcc aagtcctcta gttaattttt
    48121 ctcctatttg aactttatat tcagcttttg atgtatataa agcttgttta tctgtattta
    48181 ctgatataaa ttcaacgcct tttagttgag cttctaccat tctattgaca gcattgtttc
    48241 caccgccacc tacacctatt actttaattt gtgcacattc ttctaattct acgtcaaagt
    48301 ttagcatcat aaaccccctt ctctcatgat tcaaagttat cgtatgtatt aattatatca
    48361 ttttcttctt ttattttgtt aacctttaag taacatattc cacaaaaacg taaattttcc
    48421 tttttaaatt tcttacttat attgtcaaat attactcttt aagtataaaa taatttacgt
    48481 atatattaaa tgctctttaa tttttacgtt ttttgttcat aatattacta ataatatatc
    48541 gtctaattat agataagtta ttaaacaatc tcataccaaa aactaataca gcaacatagt
    48601 aaagagaaac tcctaacttt tctcctatat aagtcaataa tatagccaat atagcattac
    48661 ctatgaaacc agtaataaaa attacattat catagttatc ttcaaaattg gattttatcg
    48721 ctccaaaaat agaatccatt attgcaagaa tagctactga catatatatg gaataatcca
    48781 tagaatatgt aaatggaata tagtaaccta ctactacacc aaatgctaat cctcctaaaa
    48841 cccataacat aaatcttcac ctctttattt tactttgaaa cacaactaca ttacaatcct
    48901 ttttattaat tttttttact ttttctttat ttttttgtat ttttcgtttt attttgcaaa
    48961 taaatccact ttatttccat tattttcctg aacttttata ttaattccat atatatcctt
    49021 aagagattta gcatatgatt ctggagagtt tatagctgca ctcaataaat ctatatctcc
    49081 tatagctttt attataaatg gttgtccata tgtagtatca tttactgtaa tagtagctcc
    49141 tgaacatttt atcttacttg ttgctagtac tctttctcca tttatagaaa ttgctcttgc
    49201 tccagccttt tttaaatcat ttaaaaccct caaaatatct atatcatgta taatcaaatc
    49261 gtttggattc tgtccgtctt ttaactctct ctcactatcc ctcatagtaa tagttatgcc
    49321 tggccctgta acagttgaat aaccacttaa ttctttaact tcttcaagct ctttttgcat
    49381 aagtgtttgg atagattcat ttccattctt ttttgcttct ttatattcat tcaaagtttt
    49441 tttgttgttt ttaagagttt cttttaaatt ttttatttct ttttttgtat tttctacctc
    49501 actttcaata ctttcagttt gacctaatgt tatgtatact ctatttgggt ctagtgattt
    49561 tatataagtt gatatgaaaa cgcctaatat gaatgctcct aatataacta ttttcttttt
    49621 catactatta tttcccctct gctttgttta tatcactatg accatttatt tctatattgt
    49681 cttctttggt cacttttact ttggcattat aatatgtttc tatttcccag acaataccat
    49741 actttatatt aagtgccgaa gccaatgtat cagaatcacc aattgctttt attataattg
    49801 gttcttttat gacagtgtca ttcatataaa gcttgtcttc ttttaaatac atatatgtat
    49861 tagaaactat tctctggtcg tttatagata tggcacttgc ttgtgctgaa tttaatttat
    49921 ttatcattga caataataaa tcataattat atagtatact atcattttta tcagagtttc
    49981 ctaagtcttt tgtagaattt atctcaattt ttatgcctgt tccttcaaca tctgtatatc
    50041 cagctaatgt ttcatatttt tctatttctg acttaagtat gtcttgttct ccttcattgt
    50101 ttttgcctct ataagtctct atatctttct tcacactatt aacttctgat tgtagattct
    50161 ctttttcttt ttttaaagat ttaagttctt ctgtaagttg ctctcctctt ttaaaagttg
    50221 tcatccctct attttctata ttaataattt taagttgtaa actaacaaga acacccaata
    50281 caatacttcc tatgattata cttttattta taaatctttt tttcaatata tcacttcctt
    50341 acaattgtct atccttctgg actatacact gccaactttc catagttaag atttatagtc
    50401 cctccattag tatttttatt ttgcaggtca atcagaattt tacttaccct agatatatta
    50461 taatctaagt tatcatcatt agaaagtaag atttttatat tacttcttgt aagcatttct
    50521 atattgcttt ctttttttaa gtttacataa tttatttttc tataaattcc ttcttctttt
    50581 aaataattta aagttttaaa tacattctcc ttagttttat aatttttaaa ttttatagat
    50641 ttattatcat caatgctata atctacatct actatcaagt cttttttact ttcattagaa
    50701 cctcttagtt cttccaataa atttcctttt ttatctatat aacaataatt atcttcatct
    50761 tttaatactg caaatatttc tttttctttt aaacttataa ttatcttatt gggaagtttt
    50821 ctttttattt ccacattttc tatatatgga ttttttataa gtttattttt catatcttta
    50881 aaattgtatg caaaaatatt ttcatttaga tttacattta gttctttcat tatatttgat
    50941 ttggtcaccc tcttatttcc aattacatct attttcttta catcaaataa atcacttttt
    51001 acaattatac atatacaaaa agataacata agtataaaaa ctaaaactat catgacatta
    51061 ttcgtattta actttcttct ttttttcaaa tataatcaac ccctttggtt aataaataca
    51121 cctttagagc ttgtttttcc tacaaaaaaa ttataatatt taaagtcaaa tttttgcatt
    51181 ttattacata acatccaaat aaggtattaa attttataaa taaatcaata tttcatcaaa
    51241 ataaacatag catactacat actatttata tatttaaatc tgtatacata caaataaacc
    51301 cctaatttat aataatttag aaaatctaat atattataaa ttaggggtaa atatttactt
    51361 atcttttctt tattcctatt accttagctt gaccttctat acttggagtc gtttcttttt
    51421 ttatttcttt tacttcctta ataacttttt ctttttttgt ttttttagaa gttgactttt
    51481 gtgttgaatt gtatactttc attatctcat catatataag gtctatggct tcaggcttac
    51541 ctatagtttt acttgcattt gccatatcaa ccaaaagttc tctatctcct aaaagtttaa
    51601 atactgctgt atttaggctc tctggagtta gatttttttc taaaatagca attcctgccc
    51661 cttgtttttc tatactcttg gcattatact cttgatgatt ttcagcagta taagctttag
    51721 gtattattat agatggcttt ccaagagccg ttatctcagc taatgaaatt gctcctgcgc
    51781 tacctataac caaatcactt gctgcaagtg catttgccat atcttctaag taaggcacaa
    51841 ctttttggta tggtttaaga tttatatcgc taatacttcc cataaattca tcataatagc
    51901 ttttgcctgt agcaaatata aaagctatat cttcatttac catattcttt attacaagtc
    51961 tcattgcatc atttattttt cttgaacctc cactaccacc atagcaaagt accattcttt
    52021 tttcgtcact tattgataga ttctttcttg caatattttt tcttgataat aaaatttctt
    52081 ttctaactgg atttcctgta aaaactaatt tatcttctgc tgcctctgga aatcttttat
    52141 gcgaatcttc aaaacttgta agtacctttg taactgtttt agataaaatc ttattagtta
    52201 caccaggaaa agaattttgc tcatgtatta tggctggtat tttccccata gatgcattaa
    52261 ataaaacagg tccactaaca tatccaccag ttcctataac tatatctggt ttaaatttct
    52321 taacaatctt tcttgattgc tccaaacctt taaaaagctt aaaaactctt tttacattat
    52381 cgaaatctat ttttcgctta aaaccttgaa ctgttacagt ctttaattca aatccatact
    52441 taggaactat ttctgactct attccctttt ccgtcccaac aaaaattatc tcagcgtctg
    52501 gatgctcatc tcttattttg tttgcaatag ctatagctgg atacacgtgc cctccagttc
    52561 caccgcctga taataaaact ttcatcaaat catcatctcc tgttaattaa ttttgacatg
    52621 ctttgagatg tttaacacta ttcctacagc tcccataaag atggtgagtg aagttcctcc
    52681 ataacttata aatggtagtg ctacacctgt agctggcatt gatgatgtcg caactgctat
    52741 atttaaagct gcttgtattc caatttgtgc acctatacct ataacaacca tacaagcaaa
    52801 tacattagaa gtcttcaaag ctattcttac acatctgtag actaaaacta caaatagcat
    52861 aataactatt atacaaccaa tcaatcctaa ctcttctcct attatagcaa atataaagtc
    52921 attttgtggc tctggtatat aaaaatactt ttgtttactc tttcctaagc ctagaccaaa
    52981 caatccacct gaacctagtg catatagacc ttgtattacc tgatacccct taccaagagg
    53041 gtcttgaaaa gggtctaaaa atgatgtaac acgactaagt ctatagggtt cagcaattac
    53101 taatgcagca aataaagcag ccccactccc tatcatagca aatacaattt tcatatccat
    53161 tccagcaaca aatatcatta caaaagtaac tagaattaca gtacctgctg ttgacaaatt
    53221 tggctgaagt attatcaacg caaaaaatat ccctggaact acgagaagtg gtacaacacc
    53281 ttttgtcaaa gattttattt tatcataatt tttttcaatt aattttgcag ttaatattat
    53341 tgtagcaaac tttgcgattt ctgcaggttg aaatgttaaa gctcctattc ccaaccatct
    53401 ttttgctccg tttgcttcta tccctaaagg ggtcaaaact aacaataata atactactgc
    53461 tatagctcca attgctgtag catttttctt ccaaaaacta taatctattc ttgatgtaat
    53521 aatcataact ataaatccaa gtacagcata tattacattc ttttttagaa aatagtacgc
    53581 atcattgtgt ttaaatgaag attgtataaa acttgcacta aacaccataa ctattcctac
    53641 aaatactaaa agcatagtag tgtaaaacac tactccatca aattcagtct tcacccttat
    53701 gtcaatttgt tttttcaaat tttctttagg catccaacta atctacctcc attcttccat
    53761 ttaagtaagt ttagaggtaa gagattattt taaattgttt acattatctt tgaagtcttt
    53821 tcctcttact tcaaaacttt catacatatc ccaacttgca caagctggtg aaagaagcac
    53881 tatatctcca ctttttgaaa tttcataaga agtcttaact gcttcttcca tatcttttac
    53941 tatatgtatg tcattaaatc ctttattttt agcacaattt tctatatttg atgcagtttc
    54001 tcctaataag accaatgatt taacatatga ctttgcagtt tcaagaagtt catcaaaatt
    54061 acttccctta tccatccccc ctgctataag tattataggt ctatcataag actgtatagc
    54121 ttttatagtg gaatctggat tagttccctt tgaatcattt acatatatta cattgtctaa
    54181 atttcttaca aactcttgtc tgtgttccac tcctttaaat gtcataagta catcctttat
    54241 aacttctaaa tcaattttgc agacatatgc tattgctata gctgccatac aattttctaa
    54301 gttatgacct ccaggtaaac ttacatcatc tttatttaga aatttgattt tatcatctat
    54361 atctattatt atgtcattat tttctaaata tactcctcca tttacttttt tagttcttga
    54421 aaagtaaatt actttggcat tgcatttatc agctaaagat tttactatct catcatcata
    54481 gtttaataca cagaaatcct caacagtttg gttcataaat atatttgcct ttgcttctat
    54541 gtatttttcc atagtatggt gtctatttaa atggtcctct gtaatattta atattgcgct
    54601 tactttaggt ctaaattcat ctatactctc aagctgaaaa ctgcttagtt cagttactaa
    54661 cacagactct tcacttgaag tttctatagt atctattaca ggatttccta tattaccaac
    54721 tacatatgta tctcgttttg ctcttgaaaa aatttctcct accaaactag ttgtagttgt
    54781 ctttccattt gtacctgtaa tccctataaa aattggatta tccgatagtt taaaagctaa
    54841 ttctacctca ccaattatat acttgcctga attttttaat ttcaatatga atggtaggtc
    54901 tagtggtaca cctggagaca ctacaaccat atctatatca tctacatctt ctgggtgatg
    54961 tcctaatatg tattttatgt catttataga tttcaattca tcaagtatat ttctcaattt
    55021 attttcatct tttatatcat ttacgattat acttgcaccc aatttatcta aatgtttaat
    55081 tgtagatata ccagtttttg caagtcctac taataaaact ttttttcctt ttaagtccat
    55141 ttttcattcc ccctagccct aaaatactgc tattatactt atccaagcta aaacaactgt
    55201 tataatccaa aaaataaata caactcttgt ttctggccaa ccacactgtt caaagtggtg
    55261 gtgtattgga gccatcttaa agaatctctt tcttgttgcc ttaaaatatc caacttgaat
    55321 caaaactgat agagcctccg caaaataaat tcctccaatt ataggtatta taagcactga
    55381 gttagttaga actgaaaatg ctacaactgc acctcctaat gccattgaac ctgtgtcgcc
    55441 cataaacact ctagccggat atgaattaaa tcctaagaaa cctaaacatg ctccaacagt
    55501 tgctgctgct aaaactgcga cttctgtatt tccagcaata gaacttgcaa atagcataaa
    55561 gaatacagaa actattaatg ttactcctga tgctaatcca tctaatccat cagtcaagtt
    55621 tacagcattt actattgcta cgattataaa catcattatt ggtatatata atattccaac
    55681 atttatcaca aaatctgtaa atggtatcat aagttgtgaa gcacttgatg atgatgtata
    55741 ctgataaaaa gcaacataaa aagataatgc aacttgaagg attatttttt gatatgcttt
    55801 tagtccaagt gatcttttta gctttatttt tataaaatca tctaaaaagc caataaaacc
    55861 aaaacctgca atacatataa gacctactgc catatcatga ctaactttta ctcttgtaag
    55921 tccagttatt agaattgcaa caatcattat aattccaccc atagtaggtg ttccgttttt
    55981 agctagatgt gtttggggtc catcatctct aactgtctga ccaaatttaa attttctaag
    56041 cattggtata aatattggtc ctattataat tactattaaa aacgcaatca atgcggtgta
    56101 cgtaagctct gttattccta acatcataaa actcctctcc cttgtcaatt aactcattag
    56161 tttaagctta tttatttaga tattcgacta ttttttctaa tctcatgcct cttgagcctt
    56221 ttactaaaat agtgtctcct gtttttacta attcatttaa cttgttaaac acatcttctc
    56281 tattctcaaa gtgatatata ttggctgaat tgaatcctaa ttgttttgct tcttctccaa
    56341 taaacactga attttcacct atagttatta taatatcagt attattcata gatgattttc
    56401 caactaatct atgaccatac tctgaaattt cacccatttc tagtatatct ccaagtatcg
    56461 ctacccttct acctttatat cttccaagta tctttaaagc agcatccata gaatctggac
    56521 tagcattata tgaatcatta attattgtta atttttcatt ttttattatg tctagtctca
    56581 tttttgtccc tttaaaattt tttaaacctt tttttatata atctaaagaa atatttagac
    56641 acaaaccaac taatatagca gacattgcat tatatatatt atgttctcct attgttggta
    56701 taaatatttc ctcttttttc ccatctatta cacatataaa tgttaaacta tcctcttcca
    56761 tagtataact ttcacaataa acatcattgt ttttattaaa gccaaatgtt tttaacttat
    56821 atacatgttc tttttctttt aatgtagata aaaacttatc atctccattt acaattaaag
    56881 tatttgtttc atcaaagttt gaagtaatct ccatctttgc tttcaaaata ccctcttgtg
    56941 aacctagttt ttctacatgt gataatccta tattcgatat gactgcaatt ttaggattta
    57001 ctatatccac taaatatttt atttcattga atccagacat acccatctct attacagcac
    57061 actcatgttc tttatttaga ttaaataaag tcaatggaac tccaaaatga ttatttaagt
    57121 ttttttcatt ttttagtata tttaactttg cagatatggc agagtaaatc atatctctag
    57181 tagtagtttt tcccacacta cctgtaacac ctataaatgg aatatcaaat ttttctttat
    57241 agtattttga aatatctcct agagccaaag atgtatcttt tacctctatt aaatttatat
    57301 ccgaactttc taattttatt ccattacttt cattttttat aaaagtttta catccactat
    57361 catatgcaga cttcataaat gtatgcccat ctaaattttc tccaactatg gctacaaatg
    57421 cattttgggc atttgcctcc ctgctatcta taactatatc acttacacag tcattataat
    57481 ctccatatat taacttccca ttagttgcaa gtactaactc ttttattgtt aagcactcca
    57541 ttattaaact cctcctttaa aaccttagct atattctctt agcaacaaaa ggcaatgtat
    57601 accgttatat atacattgcc tacgataact cttaacttta taattatata ctatatttct
    57661 gtttttttga agatgtttat gggtatatgt taattatctg ttacttttta gttttcaaaa
    57721 tatagggtta tacttgagtc ttcattaact tttactccag gttttgggaa tatatccttt
    57781 acctttgtat cttctggaag ttctatatct gcatctaagt ctggttttaa cttcgcatcc
    57841 tccaatgcct ttacagcatc tcctattttt agatttctta catctggcac tttaacttgc
    57901 ttcttttcat actcagcttt ttcttcttct ttatatactg gtttaactcc caaatatttt
    57961 aaagagtcat tcattatttc tttcactatt ggtcctgctg tagtactacc aaatgcactt
    58021 actcctgttg gttcgtcaac aatagcaaga actactattt gcgggtcatc acaaggtgct
    58081 attccaacaa atgaacatat atactttcct ggagcatact taccatctat aactttttga
    58141 gctgtacctg ttttaccacc aagtctataa cctggtatat acgctatctt tcctccacct
    58201 tcagttacaa ctgattctgc aatttctaac atttttttag atgtttcttt agatataaca
    58261 cttcttactt tttttggttt tactgtttca gttatatttc ctttattgtc agtataagat
    58321 tttaccactc ttggttgcat taaatctcca ccattagcta ttgatgatat agctgttata
    58381 agttgtattg gagttactga tatagattga ccaaatgata ttgtagccaa ttcaactggt
    58441 cctacatttt tttcgttata cagtattccc ttagcttctc ctggtaaatc tatacctgtc
    58501 ttatccataa gaccaaatga ttctatataa tcatacattt ttccaacacc taatctgctt
    58561 cctaactcaa caaatactgg gttgcaagag ttttgtactg cttgtttaaa ttcttgtgtt
    58621 ccatgaggtc tgtaatgtct ccaacattta atctttcttc ctccaacagt tacactacct
    58681 gtacatgtga atttttctcc atctttaatt actccttctt caagagcact ggaagatgta
    58741 ataagcttaa atgtagaacc tggttcatat gtatcactta ctgctggatt tctccacatt
    58801 tgataatagc cttttatttt atctttatca ttatattttt caagttcttc ttgataatat
    58861 ggatatattg gcgtccttga gtcattaggg tcataatctg gttttgatgc taaagcaagt
    58921 atatcacctg ttttagggtt catagctatt gcagtaacct tttttgcatt atttaactca
    58981 taagctttct gtactgcttt ttcagtatag tgttgaatta cttcatctat agacaacaca
    59041 agaccattac cttgtacagg ctcataatat ttttccattc cttgtggtat ttctcttcct
    59101 gaagcatcag tacttactat aagttttcca ggctttcctt ttaacttttt atcatattgc
    59161 atttctacac cagatatacc tgttgcatct gaagaagtat gtcctaacac atatggtgca
    59221 aaattcccat atgggtaata tctttgatta tcttctgcca cccatattcc acttaattta
    59281 gcatctctta tttgacttgc cttatcatca tctatccatc tttttacttt tacaagagcc
    59341 atattttttt tgcttattaa agcgtaaata tctttataat cttcatccaa aatctcagct
    59401 accttttcgg ctgcttcttt tttatcttct acttccacag gtttacacca aacagtatac
    59461 ttagttacac ttactgctaa ctctttcata tttctatcat atatagttcc tcttttgggt
    59521 tctattggta tatctcttgt ttgttgttct agtgcttttg tactcaacca atttcccttc
    59581 ataagttgta gatacccagt cctaataaca aggcaaaaaa acaatgcaca tgctagaata
    59641 agaacgagta ccagcctttt cttacttatc ctctttactt ttctcaaatc tattccccct
    59701 agttatccac atctatatac tttatttgtc catcttttgg atagtccata ttgagcaatt
    59761 ccttagcctt tagctcaatt tcttttattg atgttttttc agtttctttt gcctttagtt
    59821 cctctaatac tatctctttt tttcttaaat ctttttgtaa ataatagata tcgtacttca
    59881 tttccgagat ttttgaataa ccacatagat tcaatattat tactgaaaaa gttgcaatca
    59941 gtaaaatgca tttagctcct atttttttct tatttctctt tttataatta ttcttttttt
    60001 tatttttata ttcatttaga ttatgtattt tataattttt tttcaaattc tcaccccgat
    60061 agtatatagt ttaaattttc ctctatacta tatttgttat taatcatatt tcttcctcta
    60121 aaatttcatc gctaaattaa tacactatta cacaatctaa ttgtattttt ttctatacac
    60181 aacaaaaacc tataaattca cttatacttt tatatgaatc tataggttag atattaattt
    60241 ctatttattt ttatcacttc tagtattttt agataatttc ttccataaat ataatatgta
    60301 actaactatc tactctctga ttcctaagtt ctccattata ttacttaata ccatctatat
    60361 ctatattttt atatctaaat tttcattata tatctcaata acaaagaaca tttcttatag
    60421 tgttaattgt tttttaattg ctttaccagt gcaacaaaat atataatact ttttaattaa
    60481 ttataataat cttatatata agattattct ttagccttat aactacttat attttttctg
    60541 ctactcttag cttagcactt cttgaacgtg gatttacttc tatttcttcc tcactaggta
    60601 atataggttt tctagttatt attttcacct cagattcttt atcacattgg catataggta
    60661 aatgctgtgg acatatacaa tctgatgcta aatgcttaaa tgcatttttc actattctat
    60721 cttctaatga atggaatgtt attatacata ttcttccacc ttcattcatt atagaagaag
    60781 catcatttat catctttgta attactccaa gttcattatt tacttctatt cgtattgcct
    60841 gaaaagttct tttagctggg tgaggtccat ctattctggc tttcttaggg atagcttttt
    60901 taattacatc tactaattct cctgtagttt ctattggttt gtttgctctt tcttcaacta
    60961 taaatttagc tatacgctta gcccagttat cttctccata atcttttatt atcttagtta
    61021 attcatcttc tgtataagta tttacaacat catatgcaga aaactcacac ctaacatcca
    61081 ttctcatatc aagtggtgca tcttgcatat aagaaaatcc tctatcagct tcatcaagtt
    61141 gatgagatga aactcctaaa tcagctaata caccatcaat tttgtaaact cctatttttt
    61201 ctaattcctc ttttatattt tcaaaattgc tgtgaacaaa cttcactcta ctttcatatt
    61261 cactcaatct ctcttttgct gtgcttatag catttttatc ttggtcaaac cctataaata
    61321 atcccttatc tgacagtttt tttactattt ctttagaatg tcctgctcct cccatagtac
    61381 agtcaacata cacgccatct ggctttatat ttaaattctc tatacactca tttaaaagaa
    61441 ctgatacatg atgaaattcc atagttacct cccttaaatt cactttttaa actattcttc
    61501 actaatatta tttttatttt tctttgataa ataaacatgt gcaattatgc caccaataac
    61561 tccaattaga cttataactt gtgccattct aagtggtcct aacattaaac tatctgttct
    61621 taatccctct ataaaaaatc ttcctattga atataaagtt atataagtaa ctataacttg
    61681 accttcatat tttttatttt ttctaaatag taataaaact ataaatattc caaaatccca
    61741 tatagactca tataaaaaag ttggatgtac ctttactcca tcaaccatta ttccccaagg
    61801 taaattggta gcacctccat gtgcttctcc attaataaaa tttccccatc ttccaatagc
    61861 ttgtgctaaa ggcattccaa gtataactgt atcagccatt tttaagaagt taatattttt
    61921 aatcttagtg tatatataac cagctaatat tccaccaatt aaccctccat gtatagcaag
    61981 tccaccacct ctaaaattaa aaatttgaga catattttga gcatagtaac tccaattaaa
    62041 tacaacataa tagattcttg cacagattag tccaactgga attgctatta tagctatatt
    62101 taatacatca tcttctttaa ttcccactct ttttgcttct tttattgcta ttaaagttcc
    62161 taaaatcatt ccacatgcca taagtattcc ataccacatg atgtctatgc caaacagtgt
    62221 aaatgctact ctatccataa cgtcacctct ttgtattaat tgaaaatatt tccaaagcaa
    62281 tatgctataa ttacaattaa ttgtaattat actaaattat gataacacat taatgttaat
    62341 tctacaaaaa atattaaaat ttattctaca actccctaca ctatattata tctaattact
    62401 ataaaatttt ttaaactaaa tctctcatga ctaaagttac aagtgtacat agatattttt
    62461 taatcaaaaa gattgatgca tatatacatc aacctcttct aattcttatc tatagctctt
    62521 aaatttttac ctcaatttat ataaatatat tttataaatt tgttttacca aaataaacat
    62581 ttaaaaacat aaactaatac ttaattagtt attcttatta tgattaagtt tctatttagg
    62641 ctctacaata gaaataacac aatactcttc tttaaaatgc tcttttaatc tttcttcaac
    62701 ttcctcaaaa gtaatatctt taataatatc taaataatcc aatagattta tatccttaaa
    62761 aacataagat ataaaactat tacctataaa gtttatagaa tcaaagcact taataaatga
    62821 ccctattttt ttctttttag ttctctcaaa ctcttctttt gataatcctt ctttttttga
    62881 tttttctata taatcaagaa ttatttcttt tactttttta ggctctttag aatctccagc
    62941 tattatgcta aaagcataat ccacttgaga cgaaaatcca gctccaaaat tttcatttat
    63001 taaaccttgc atatacaaat cttcataaag cttacttcct tttttaaata acatccctac
    63061 aagtatatca gttacaatct ctttacgtaa aagttctttc ccttttaaac caacattgct
    63121 atctttaaaa cctatgttga acataggcat agatataggg aatttttcta taacctcttt
    63181 ttcttttaca ctttctggtt cttctggata aaatctttct atactcttag agagtctgtc
    63241 tactttgtaa ttgtttgact ttttagttac atctataact ttttctacat ctaagtcacc
    63301 aacaacaaat aaagccatat ttcctggatt atagaaagta ttataacatt tatatagctc
    63361 ttccttagtt atcttatata tactatcaac agtacctgct atatcaattc tagcaggata
    63421 atttacatac attgccttca agcaattaaa gtatacattc caatcagggt catcattgta
    63481 catttttatc tcttgtgcta ttataccttt ttccttttca acattttcat ctgtaaaata
    63541 aggtgtttga acatagtcaa ttagatgttc taaactctca taaaaatttt cagtagcaga
    63601 aaataagtag gctgtcattg taaaattagt aaatgcattt gcatttactc ctaattttga
    63661 aaatttatca aatgcatctc ctccatcagg ttgctcaaac atcttatgct ctagaaaatg
    63721 tgcaatacct tcattcactc taattttctt atcttctcca attggtacaa attctaagtc
    63781 atttgaacca taattagtag ccaaaatagc atactttttc ataaaacccc ttttaggcat
    63841 aaaatataca tctaatccat tttgcaattt ctcataataa acttcttctt tcaatatatc
    63901 attaactatt ttttccatag acatctcctc cattaatttc tcaagaagta tacagtatca
    63961 agctctatat tttttatagc ttcaactata tctttttttg taaccttttc tatactagat
    64021 attatgtctt gtacttcaga atttgtcttt gccatagact gagagaaaac aaaatcagac
    64081 ataccaccta tattatcagt tatagatttc atagaattaa ctaaagcaag tttactgttt
    64141 tctaattctt catcagatat atcacctgct tttacacttt ctacttgttt ttttatcaat
    64201 tctacagctt tatcataatc tttagtttct ataccagatg atataaacat gatactttta
    64261 tacttctcta ttgaagagaa tatatagtaa cataaacttt ctttttctct tacattaaca
    64321 aataatttag agtgtggacc accacctaag acattgctcc caactactaa agcataatat
    64381 ttatctatgt ctgcataatc cacatttgct ctataaccca taactaactt accttgagtt
    64441 atttccattt gttcatctat aacttttacc tcatccacat tttttataaa atctgctctt
    64501 ggtatattta taatttcttc tctttcaaat tttagatttt tacttattat atctacaact
    64561 ttatcttcat caaaattacc ttctacaact atatctatag gtgatgtttt aagtatgttt
    64621 ttataatgtt catataactc tcttgaagtt atactatcta tttcatcttc ataaccaaat
    64681 tcacttacac tatatctctc tcctttacac atagcctcaa tacatttatc ttgcgcatat
    64741 tcctttttat catttattat tgattgtatc ttttctctta aattctcttt ttcaatattt
    64801 aaatattctt ctttaaaccc accatctaca acaagcgtat tatttattac ttcattaaaa
    64861 aattctacta cttcttcaaa tatactctca tctaaatact tttcacttat gttaattact
    64921 ttaaaactca atacttgacg ttctccacgt tttacagcat cagctcccat agatgaacca
    64981 tataaatcat ctaatttatt ggatattgct ctagcactag gatatttagc gcttccactt
    65041 gctattattg atggtattag agcatttttt gtagtttctt tttcatccaa tagtctctga
    65101 acatataaac ttataagatt cgatttaaac ttttctgttt ttatcaaagt aagattaata
    65161 ttattaccta aatttattat ttttttagta ttaaccatat gtacctccta tttttattta
    65221 aacatcaatt ttaaaattga aatttattta ttttttaatt acatatactc acatataaaa
    65281 accttctatt taattatatc ctttttatta ttttctaaaa gcaatatttt tatttaaatt
    65341 aaatacaaat attatttaaa tcaatatgct ttaaagtcta gtttacaagc ttgatatata
    65401 tgatgtataa tcaatatgta tgtctataat taaaacaatt ttgcaatcct atagattgat
    65461 tgtttaaagt tatataaaga atataaaaaa gaataagaga gaggacgatt aatatgaaat
    65521 taggtatagt tggtttacca aatgtaggta aaagcacact atttaacgca ataactcaag
    65581 caggtgcaga atctgcaaat tacccttttt gtacaataga cccaaatgtg ggagttgtat
    65641 ctgttccaga tgaaagatta aacaaactac aagaattata taattctgaa aaaatagttc
    65701 ctactgctat agaattttgt gatatagcag gtttagttag aggagcttct aaaggagaag
    65761 gtttaggaaa taaattctta tcacatataa gagaagttga tgcaatagtt catgttgtta
    65821 gatgttttga ggatgaaaat gttgtacatg tagatggttc tgtagaccca cttcgtgata
    65881 tagaaactat aaacttagaa ttaattttct cagatataga gattcttgaa agaagaatta
    65941 ataaaactca aaaagctgct aaggctgata aaactttagg ttctgaactt gatttattaa
    66001 aatcaataat gtctacttta gaagaaagta aatgtgtaag aactatggaa tttacagaag
    66061 atgaacaaac attcgtaaat tcattggatt tacttacatc taagcctgta atatatgctt
    66121 caaatgtatc agaagatgat ttagctgata atggagaaaa taataaatat gttcaacaag
    66181 ttaaagcatt tgcagaaaca gaagatgccg aagttgttgt agtatgtgca caaatagaag
    66241 cagaaatttc tgaacttgat tctgctgaag aaaagaaaga gtttttagaa acattaggtc
    66301 ttgaacaatc agggcttgat aagcttataa aatcttctta tgctttactt ggtttaattt
    66361 cattcttaac tgctggtcca aaagaagtta gagcatggac tataaaagtt ggaagtaaag
    66421 ctcctcaggc aggaggaaaa atacattctg atatagaaag aggatttatc agagcagaaa
    66481 caatagcctt taatgatttg gttgagcatg gtactatggc tgctgctaaa gaaaaagggt
    66541 tggttaaatt agaaggtaaa gaatacatag ttaaagatgg agatgtaata ttatttagat
    66601 ttaatgttta aaatgattaa tcgtatacac tttgactatt atatataata actaaa
//
LOCUS       DAMJWC010000013        64169 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMJWC010000013 DAMJWC010000000
VERSION     DAMJWC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.013"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            124..1320
                     /locus_tag="PC503_001023"
     CDS             124..1320
                     /locus_tag="PC503_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF2527035.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1413..1937
                     /locus_tag="PC503_001024"
     CDS             1413..1937
                     /locus_tag="PC503_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF2527036.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1962..2138
                     /gene="rpmF"
                     /locus_tag="PC503_001025"
     CDS             1962..2138
                     /gene="rpmF"
                     /locus_tag="PC503_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF2527037.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2345..2902
                     /gene="fapR"
                     /locus_tag="PC503_001026"
     CDS             2345..2902
                     /gene="fapR"
                     /locus_tag="PC503_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF2527038.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2913..3935
                     /gene="plsX"
                     /locus_tag="PC503_001027"
     CDS             2913..3935
                     /gene="plsX"
                     /locus_tag="PC503_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF2527039.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3961..4947
                     /locus_tag="PC503_001028"
     CDS             3961..4947
                     /locus_tag="PC503_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF2527040.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5056..5985
                     /gene="fabK"
                     /locus_tag="PC503_001029"
     CDS             5056..5985
                     /gene="fabK"
                     /locus_tag="PC503_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF2527041.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6001..6951
                     /gene="fabD"
                     /locus_tag="PC503_001030"
     CDS             6001..6951
                     /gene="fabD"
                     /locus_tag="PC503_001030"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF2527042.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6951..7700
                     /gene="fabG"
                     /locus_tag="PC503_001031"
     CDS             6951..7700
                     /gene="fabG"
                     /locus_tag="PC503_001031"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF2527043.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7754..7978
                     /gene="acpP"
                     /locus_tag="PC503_001032"
     CDS             7754..7978
                     /gene="acpP"
                     /locus_tag="PC503_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2527044.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8007..9245
                     /gene="fabF"
                     /locus_tag="PC503_001033"
     CDS             8007..9245
                     /gene="fabF"
                     /locus_tag="PC503_001033"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF2527045.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADLMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9471..11189
                     /locus_tag="PC503_001034"
     CDS             9471..11189
                     /locus_tag="PC503_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2527046.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11220..13220
                     /locus_tag="PC503_001035"
     CDS             11220..13220
                     /locus_tag="PC503_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527047.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13571..13816
                     /locus_tag="PC503_001036"
     CDS             13571..13816
                     /locus_tag="PC503_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2527048.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13851..14576
                     /locus_tag="PC503_001037"
     CDS             13851..14576
                     /locus_tag="PC503_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2527049.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14598..15911
                     /locus_tag="PC503_001038"
     CDS             14598..15911
                     /locus_tag="PC503_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2527050.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKIYGENLKKIV"
     gene            16117..16656
                     /locus_tag="PC503_001039"
     CDS             16117..16656
                     /locus_tag="PC503_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527051.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16745..18730
                     /locus_tag="PC503_001040"
     CDS             16745..18730
                     /locus_tag="PC503_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDF2527052.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18954..19922
                     /gene="spoIIIAA"
                     /locus_tag="PC503_001041"
     CDS             18954..19922
                     /gene="spoIIIAA"
                     /locus_tag="PC503_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF2527053.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19912..20433
                     /locus_tag="PC503_001042"
     CDS             19912..20433
                     /locus_tag="PC503_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF2527054.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20450..20647
                     /gene="spoIIIAC"
                     /locus_tag="PC503_001043"
     CDS             20450..20647
                     /gene="spoIIIAC"
                     /locus_tag="PC503_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF2527055.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20663..21049
                     /gene="spoIIIAD"
                     /locus_tag="PC503_001044"
     CDS             20663..21049
                     /gene="spoIIIAD"
                     /locus_tag="PC503_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF2527056.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21134..22339
                     /gene="spoIIIAE"
                     /locus_tag="PC503_001045"
     CDS             21134..22339
                     /gene="spoIIIAE"
                     /locus_tag="PC503_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF2527057.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22399..23016
                     /locus_tag="PC503_001046"
     CDS             22399..23016
                     /locus_tag="PC503_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF2527058.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23028..23582
                     /locus_tag="PC503_001047"
     CDS             23028..23582
                     /locus_tag="PC503_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF2527059.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23609..24298
                     /locus_tag="PC503_001048"
     CDS             23609..24298
                     /locus_tag="PC503_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF2527060.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNVDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24408..24770
                     /locus_tag="PC503_001049"
     CDS             24408..24770
                     /locus_tag="PC503_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2527061.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24855..25361
                     /gene="nusB"
                     /locus_tag="PC503_001050"
     CDS             24855..25361
                     /gene="nusB"
                     /locus_tag="PC503_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF2527062.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25345..26415
                     /locus_tag="PC503_001051"
     CDS             25345..26415
                     /locus_tag="PC503_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF2527063.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26412..27617
                     /locus_tag="PC503_001052"
     CDS             26412..27617
                     /locus_tag="PC503_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF2527064.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27619..27834
                     /gene="xseB"
                     /locus_tag="PC503_001053"
     CDS             27619..27834
                     /gene="xseB"
                     /locus_tag="PC503_001053"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF2527065.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27837..28724
                     /locus_tag="PC503_001054"
     CDS             27837..28724
                     /locus_tag="PC503_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF2527066.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIGKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28754..29191
                     /locus_tag="PC503_001055"
     CDS             28754..29191
                     /locus_tag="PC503_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF2527067.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29225..31090
                     /locus_tag="PC503_001056"
     CDS             29225..31090
                     /locus_tag="PC503_001056"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF2527068.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31223..32035
                     /locus_tag="PC503_001057"
     CDS             31223..32035
                     /locus_tag="PC503_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HDF2527069.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32055..33734
                     /gene="recN"
                     /locus_tag="PC503_001058"
     CDS             32055..33734
                     /gene="recN"
                     /locus_tag="PC503_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF2527070.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33948..34814
                     /locus_tag="PC503_001059"
     CDS             33948..34814
                     /locus_tag="PC503_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527071.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34907..35398)
                     /locus_tag="PC503_001060"
     CDS             complement(34907..35398)
                     /locus_tag="PC503_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527072.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35459..35899)
                     /locus_tag="PC503_001061"
     CDS             complement(35459..35899)
                     /locus_tag="PC503_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527073.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36060..37118
                     /locus_tag="PC503_001062"
     CDS             36060..37118
                     /locus_tag="PC503_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2527074.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37260..38084
                     /gene="spo0A"
                     /locus_tag="PC503_001063"
     CDS             37260..38084
                     /gene="spo0A"
                     /locus_tag="PC503_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF2527075.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38497..39618
                     /locus_tag="PC503_001064"
     CDS             38497..39618
                     /locus_tag="PC503_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527076.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39636..40511
                     /locus_tag="PC503_001065"
     CDS             39636..40511
                     /locus_tag="PC503_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF2527077.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40535..41227
                     /locus_tag="PC503_001066"
     CDS             40535..41227
                     /locus_tag="PC503_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2527078.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41235..42059
                     /locus_tag="PC503_001067"
     CDS             41235..42059
                     /locus_tag="PC503_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2527079.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKNLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIVFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42064..43131
                     /locus_tag="PC503_001068"
     CDS             42064..43131
                     /locus_tag="PC503_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF2527080.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43133..43669
                     /locus_tag="PC503_001069"
     CDS             43133..43669
                     /locus_tag="PC503_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2527081.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43737..44342
                     /locus_tag="PC503_001070"
     CDS             43737..44342
                     /locus_tag="PC503_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF2527082.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKSR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44354..45268
                     /locus_tag="PC503_001071"
     CDS             44354..45268
                     /locus_tag="PC503_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2527083.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAAEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45310..46482
                     /locus_tag="PC503_001072"
     CDS             45310..46482
                     /locus_tag="PC503_001072"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF2527084.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIEGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46529..47341
                     /locus_tag="PC503_001073"
     CDS             46529..47341
                     /locus_tag="PC503_001073"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF2527085.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47545..48870
                     /locus_tag="PC503_001074"
     CDS             47545..48870
                     /locus_tag="PC503_001074"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF2527086.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49083..50162
                     /gene="mltG"
                     /locus_tag="PC503_001075"
     CDS             49083..50162
                     /gene="mltG"
                     /locus_tag="PC503_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF2527087.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFSYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50334..51008
                     /locus_tag="PC503_001076"
     CDS             50334..51008
                     /locus_tag="PC503_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF2527088.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRKYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50995..52242
                     /locus_tag="PC503_001077"
     CDS             50995..52242
                     /locus_tag="PC503_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2527089.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEIYEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52314..53984
                     /locus_tag="PC503_001078"
     CDS             52314..53984
                     /locus_tag="PC503_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF2527090.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDIDKSMKKELEKNGIMVEEKTMRYAKDGL
                     LSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKT
                     VDNKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQND
                     ISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNT
                     NEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGL
                     DEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNM
                     NTIKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLN
                     KKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54081..54365)
                     /locus_tag="PC503_001079"
     CDS             complement(54081..54365)
                     /locus_tag="PC503_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2527091.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54388..55905)
                     /locus_tag="PC503_001080"
     CDS             complement(54388..55905)
                     /locus_tag="PC503_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2527092.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKAYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56030..56851)
                     /locus_tag="PC503_001081"
     CDS             complement(56030..56851)
                     /locus_tag="PC503_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2527093.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57042..58469
                     /locus_tag="PC503_001082"
     CDS             57042..58469
                     /locus_tag="PC503_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HDF2527094.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISVNALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     gene            58619..58771
                     /locus_tag="PC503_001083"
     CDS             58619..58771
                     /locus_tag="PC503_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527095.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     repeat_region   59425..59717
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=59425..59453
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60004..60228)
                     /locus_tag="PC503_001084"
     CDS             complement(60004..60228)
                     /locus_tag="PC503_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527096.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            60939..61094
                     /locus_tag="PC503_001085"
     CDS             60939..61094
                     /locus_tag="PC503_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HDF2527097.1"
                     /translation="MALDVKIEVKIIKDVVILNITHWKKETSLLTVKIARSQGDLSYV
                     KYFANES"
     gene            61340..61591
                     /locus_tag="PC503_001086"
     CDS             61340..61591
                     /locus_tag="PC503_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527098.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(62801..63184)
                     /locus_tag="PC503_001087"
     CDS             complement(62801..63184)
                     /locus_tag="PC503_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527099.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63311..63655
                     /locus_tag="PC503_001088"
     CDS             63311..63655
                     /locus_tag="PC503_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527100.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            63838..64053
                     /locus_tag="PC503_001089"
     CDS             63838..64053
                     /locus_tag="PC503_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527101.1"
                     /translation="MHINQTGFISNELGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVRGGSSWAFNFIVQP"
BASE COUNT        25708 a         6655 c        11503 g        20303 t
ORIGIN      
        1 gtttaatgta tacaataata tatctataac aaaataataa aagatagagt tttatttaga
       61 catttattac aaatcaaaat ttattacata ttatttataa aaaaatctaa ggaggaaata
      121 ataatgaaaa tattagtatt aaactgtggg agttcttcat taaaatatca attaatagat
      181 atgaataatg aagaagtttt atgtatagga ttggttgaaa gaataggaat agaaggttct
      241 atattaaaac atgaaaaagc aggtagagat gataaatacg ttgttgaaca accaatgaag
      301 gaccacaaag atgcaatagc attagtttta gaagctgttg ctcatccaga atttggtgca
      361 gttaaagaaa tgaaagaaat agatgcagta ggacataggg ttgtacatgc tggagaaaaa
      421 tttgcaactt cagtagtaat aactccagaa gtagaagaag ctttaaaaga atgtatagat
      481 ttagctccac ttcataatcc agcaaacata atgggaatag atgcttgtaa agctatactt
      541 ccagatgtac caatggtagg tgtatttgat actgctttcc atcaaacaat gcctaaatct
      601 tcatacttat atggtttacc tcatgagcta tatactaaat atggggtaag aagatatgga
      661 ttccacggaa cttctcataa ttatgtatct caaagagcag cagagatatt aggaaaagat
      721 ataaaagatt taaaaatagt aacttgtcac ttaggaaatg gtgcttctat agctgctgtt
      781 gatggtggaa aatgtgtaga tacatctatg ggattcactc cattagaagg attaataatg
      841 ggaactagat gtggagatat agacccagct atattaccat tcttaatgag aaaagaaggt
      901 ttagatgctg atggattgga taaattaatg aataaagaat ctggagtata tggaatgact
      961 ggaatttcta gtgacttcag agatatagaa gatgcagcta aaaatggaga cgaaagagct
     1021 caagctacat tagaagcgta tgttaaaaaa gtacaaaaat atataggcgc ttatgctgct
     1081 gaaatgaatg gattggatgt tgtagtattt actgcaggcg ttggtgaaaa tggaaaggct
     1141 ataagagcag atattgcttc taacatggag tttttaggaa tgaaattaga taaagaagct
     1201 aatgatgtta gaggaaaaga aacagtaata tctactgctg attctaaagt aaaaatgctt
     1261 ttaataccaa ctaatgaaga attaatgata gctagagata cattaagatt ggtaaaataa
     1321 ttaaattaaa cctatgccta tcaagtaaaa atacttgaca aacaaatgct agatttgtat
     1381 aataaatttg gtgatatgtt gaggtgaact taatgaaagt tagcatagaa aaaataaata
     1441 gaaaagaaac tgacaaaata gacttgaatt tttgtgaaaa aattgatact attagttatt
     1501 gtgatgagat ttacaaatta gtatcacctg taaatttaaa agggaaagtg tcaaagacta
     1561 ataaaggttt gtatctagat atagatgtca attttacaat tgttgacaat tgttcaagat
     1621 gtcttaaaga agtagaaata ccactagagt attctataca aggtttttta gtaaaagaag
     1681 aagattatga tgaagatgag tttgaggaat ttgatccttt tatattcgat ggtgaagaaa
     1741 tcgaccttat tgatataata gaacagacat tagattttaa tgtacctcat aaagttcttt
     1801 gtagtgaaaa ctgtaaaggt ctttgtcaag tatgcggggc aaacttaaat gaagaagagt
     1861 gttcttgcag tgaaattaca aacgatgagg aatacataga tcctcgtttt gctaaattaa
     1921 aagatttatt taattaaatt ttgactaagg aggtggcgta aatggcagta ccaaagcgta
     1981 aaacgtctaa atcaaacaca aaaatgagaa gagcagctaa ctcaaagatg gaagcaacag
     2041 gatttgtaag ttgcccacaa tgtcatgagc caaaattacc acatagagtg tgtccagact
     2101 gtggatatta taaaggtaaa gaagttgtgt ctaagtaata gcttctaaaa agcatgtaga
     2161 gtatactcta catgtttttt ttgtacatat aaaaaaataa gataatttac tagagaaaat
     2221 aagtggattt tatgcatatt aaaaaataga aaaataataa tataagtatt gaaaattttt
     2281 gtgtgttact atatactact attagtagct ggtactaatt acagctataa aatttggagg
     2341 gaacatgaaa aagaaaagta aagcccaaag acaaaaagag cttatagata tgctaaagac
     2401 agatcctttt tatactgatg aagaattatc aagtctgttt gatgtaagta tacagaccat
     2461 aagattagat agaatgagtc taaacatacc agagctaaga gaaagagtca aatcaatagc
     2521 agaaactcag agttcaaaag taaagacttt aggagtaaag gaaattacag gagaaatcat
     2581 tgatttatct gtagggcgat taggtatatc tatgttagaa gttacacagg acatgattta
     2641 ctctaagact aatactttaa aagatacgta tattttttct ctagcagatt cattggcaat
     2701 ggctataata gatgcaccta aggttattat gagagttgca aatgtaaaaa gttttaagtt
     2761 gatagaacaa caagataggc ttatagcaaa agcagaagtg tatagaaata tagataaaaa
     2821 gcattatgta aaagttgtta tcaacaataa agcccaagag caaatattta gaggaaagtt
     2881 tatctttgaa gaattagatt aggagggaaa ttatgaaaat agtaattgat ggaatgggtg
     2941 gagataatgc acctaaatct aatgtagaag gcgcagtaaa tgctataaaa gaatatcagg
     3001 ttgatttaat aatcacagga gataaagatt tacttgaaaa ggaattttca aattatgaat
     3061 ttgatagaaa taaattagag atagttcata ctactgagat tatagaaaac gaagataaac
     3121 cagtaaaggc tataagaagt aaaaaagatt catctatggt agtagcatta aatcttgtaa
     3181 aagaaggaaa ggcagatgct ataatatcag ctggaaatac aggagcctta cttgctggtg
     3241 gattatttgt tgttggtaga ataaaaggaa tcgatagacc ttgcttatgt tcagcaatac
     3301 caaatgtaaa gcgaggaatg acacttatag cagactgtgg cgcaaatgca gattgtaaac
     3361 ctaagaatct agttgaattt gcagctatga gtaatattta ttcaagaaaa gttttaggtc
     3421 ttgaaaatcc taaggtagca ttagcaaatg ttggactaga agaaggcaaa ggcaatgatt
     3481 tagtcaaaag gtcatatgaa gaaattaaaa aattagattt aaattttata gggaatgtag
     3541 aagctagaga agttataaat gcatacacag atataatcat atgtgatgga tttacaggta
     3601 atatattact taaatctgct gaaggtgtag cactttcagt tatgagtctt ataaaggaaa
     3661 cttttatggc cagtacaaaa agtaaaatag gagcattact tataaaggat gatttaagaa
     3721 aattaaaaag ttttatagat tattctgagt atgggggagc tccactttta ggtctaaatg
     3781 gaggagttat aaaagctcat ggtagttctg atgctaaagc tataaaaaat gctataaatc
     3841 aaggaataaa attttcaaag ggaaaagtcg ttgaagatat taaccaattt ataagcaaat
     3901 acaatgaaga aaataaaaat aacgaagatg aataaactcg ttttggaggt ttaatatata
     3961 atgaatacaa aggctggaat attaggagta ggaagttatc tacctgagca atcatatgat
     4021 aattttcact tcgaaaaaat aatggataca tcagatgagt ggataagtac tagaactggt
     4081 attaaggaaa gaagatttgc caaagagtct gaagcaactt ctgacttagc atctaaagct
     4141 gccttaaaag ctatagaatg tgcaaagtta aacgtagagg atatagagct gattatatta
     4201 gctacaatta ctcctgatat gtctttgcct tcaactgcat gtatagtaca agatgcaata
     4261 ggagcagtaa atgctactgc atttgatata tcagcagctt gttctggatt tgtatatgga
     4321 gtaactattg caaagcaatt tgtggaaaca ggttgctata aaaatgtgct tgtaatagga
     4381 gcagaaactt gttctaagtt tttaaattat gatgatagaa caacagcagt attgtttgga
     4441 gatggagctg gagcagctgt tattggccct gtaaatgagg gtggaatact gtctacacat
     4501 atgggctctg atggtaaagg aaaagattgt ttaaaagtac ctgctggagg ttcaagactt
     4561 aaggcaagta aagagactgt agaagctaat ctacatacaa tagaaatggc aggtagtgat
     4621 gtgtttaaat ttgcagttag aaagatggca gaaacttctt taagagctct tgaaaaagca
     4681 aatctaaata caactgatat agactactta gtgccacatc aagctaatat aagaatcata
     4741 caagcttctt ctaagagatt agagcttgat atgaaaaaag tttatgtaaa tatagacaaa
     4801 tatggaaata tgtctgctgc atctatacca gtagcattag atgaagctta tagagaaggt
     4861 aaaattaaaa agggtgataa tgtagtttta gttggctttg gtggaggtct aacttggggg
     4921 gcttcagttg tcaagtggac tttatagtat aaaatatcta aaatgattta attaacaaaa
     4981 ttaaacttat acacaaaata aagttgatta ataataaaaa gtttactttt atgatttcaa
     5041 gtgaaggaga attgtatgaa taaaatttgc aaaatattaa atataaaata cccagttatc
     5101 caagggggaa tggcatgggt agctactgca tcattagcaa gtgctgtatc taatgcagga
     5161 ggacttggca taatagcagc aggaaatgca ccaaaagaag ctataaagaa agaaattgtt
     5221 gagtgtaaaa aattaacaga taagcctttt ggagtaaatg taatgcttat gtcgccattt
     5281 gttgatgata taattgattt gattatagaa gaaaaagttc aagttattac tactggtgct
     5341 ggaaatcctg caaagtatat ggatagatta aaggaagctg gaacaaaggt tattcctgta
     5401 gtacctacaa tagctttggc acaaagaatg gaaaagctag gagctacagc agtaatagca
     5461 gaaggtactg aaggtggagg acatatagga gaacttacta ctatggtctt agttccacaa
     5521 gttgctgatg ctgtaaacat acctgtaata gctgctggag gaattgtaga tggtagagga
     5581 attgcagcat catttgcatt aggtgccagt gcagttcaag taggaactag atttatttgc
     5641 agtgaagagt gttctgtcca ttcaaactat aaaaacttag tactaaaagc aaaagataga
     5701 gatgcaattg taacaggaag aagtactggt catccagtaa gaacattaaa aaataaacta
     5761 tcaaaagaat ttttaaagat ggaacaaaat ggagctactc ctgaagaact ggataaaaaa
     5821 ggtacaggag ctttaagatt tgcaacagta gatggagaca tagaaaaagg ttcatttatg
     5881 gcaggtcaaa gtgctgctat ggtaaaagaa ataacacctt gtaaggaaat tatagaggct
     5941 atggtaaatc aagcaagaga gattatgcca gcaatagaac tgtaaatcag gaggagcaag
     6001 atgggaaaag ttgcactagt attccctggt caaggagctc aatatgtagg tatggccaag
     6061 gatttatatg aaaataatgc tgttgctaaa agtgtaatag atgaggctag tgatgcctta
     6121 aatatggatt taaaaaacct tatgtttaat ggaaatgaag aagaactttc taaaactgaa
     6181 aacactcaac ctgctatggt tacacatagt gtagcagtat taaaagcggt acaagctcaa
     6241 atagatttaa aatataatgc atgcttagga ttatccttag gagagtatag tgcgttggtt
     6301 gcagcagatg caattgactt taaagatgct gtatgtttag ttaaaaaaag aggtaagttt
     6361 atgcaggaaa cagttccagc aggtgttgga gctatggcag cagttttagg tttagataga
     6421 aatgtacttg aaaatgtggt taaagatata caaggaggta ttgtagaagt agcaaattac
     6481 aattctcctg gacaaatagt tatatctggt gaaaatgaaa agatagaaga agcaatggta
     6541 aaatgcaaag aagcaggagc aaaaagggca gttaaattaa atgtaagtgg accttttcac
     6601 tcatcaatgt taaaagaagc tggtgtaaaa ttggccagtg aattagaaaa agttaacata
     6661 actaaaccta aagttgatgt ggtggcaaat gtaaatgcag attactataa aaacgaaggt
     6721 aaagacctgc ttataaaaca agtaagttca tctgttcttt gggaagattc tatagaaaga
     6781 cttttaaatg atggatatga tacttttata gaaatgggac ctggaaaaac tttaaaagca
     6841 tttattaaga aaatagcttc caataaaaaa gcaaatgtca atatttataa tatagatggt
     6901 atagattctc ttaatgaatt tgtacaaaat tatagaaatg gagagatata atgataaatc
     6961 ttacaggaca agtagcagtt gttactggtg gttctagggg tataggaaaa gaaatagcaa
     7021 aaaaactagc atcttttgga gctgatgtag taatcaatta tacttctaaa gaagatgaag
     7081 cactaaaaac taaaaatgaa atagaaagta tgggggtaaa gtgtacctct ataaaatgtg
     7141 atgtgtctaa atttgatgaa gtgaatcaaa tgatagattc tgttgtaagc gaatttggaa
     7201 aaattgatat attggttaat aatgcaggca taactaaaga tggtctgctt atgagaatga
     7261 aagaagaaga ttttgataga gttatagata taaacttaaa aggtgtcttt aattgtacaa
     7321 aagcagttac taaacctatg atgaaaaaga agtatggaag aataataaat atgacttcag
     7381 tagttggaat tatgggtaat gcagggcaaa ctaattattg tgcatcaaaa gcaggtgtaa
     7441 ttggatttac aaaagcttct gcaagagagt tagcatcaag aaacataaat ataaatgcag
     7501 tagcacctgg atttatagaa acagatatga ctaaagtact aagtgatgat gtaaaagaat
     7561 caacactagc aaacatacca aagaaatctt atggtaaacc agaagatgta gccaatgccg
     7621 tagcattttt agttagtgac atgtcaagtt atataacagg acaagtaata aatgtagatg
     7681 gtggaatggt aatgcaataa taatttaaaa agtagagaaa tctattaaaa taaaaaattt
     7741 taggaggtac acaatgttta ataaagttgt agaaataata atagagcaat taggagtaga
     7801 agataaagaa ataactatgg aaacatcatt aatgaaggat ttagaagcag attcattaga
     7861 tgcagtagaa ataataatgg cacttgaaga tgaatttggt atagaaatac cagatacaga
     7921 agcagaaaac ttcaaatcta taggagatat agttaagtat atagaagcta ataaatagtc
     7981 gagctttaaa aaagtggagg tatccgatga ataaaagagt agtaataaca ggacttggat
     8041 gtgttacgcc gttgggaaca ggaaaagaag agttctggag taatataaaa tctggagtat
     8101 ctggtataga taaaataact aattttgatg ctagcacata tcaaactcag atagcaggag
     8161 aagttaagaa ttttcatcca gaagaatata taagtaaaaa ggaattgaag agattagata
     8221 aatttgctca atttgcaata gtatctgcta aattagcagt tgaagatgca aatcttgatt
     8281 tagataaagt tgatagagaa cgttttggtg ttataatagg ttctggaata ggtggagttg
     8341 aagctataga aactcaacat aaaattcttt tggaaaaagg aaataaaaga gtaagttcac
     8401 tttttgtacc tatgatgata ggaaatatgg cagctggtca agtttcaata tttttaggag
     8461 caaaaggacc taacactaat gtatgtacag cttgtgcatc aggaactcat tcaataggtg
     8521 atgcttttaa ggtaattcaa agaggtgatg cagaccttat ggtagcaggg ggttctgaag
     8581 ctgctgtaac aggtcttgct tttgctggat tctgtaacat gaaggctatg tcaactagaa
     8641 atgatgaccc taaaactgca tcaagaccat ttgataaaga cagagatggt tttgtaatgg
     8701 gagaaggagc aggtattgtt atcttagaag acttagaaca tgctttagca agaggtgcta
     8761 aaatatatgc agaagtagtt ggatatggtt taactgctga tgcataccat atgacaactc
     8821 cagctgaaaa tggagaggga gcagctaggt ctatgaatat ggctttgaaa gatggaaatg
     8881 ttccattaga agaagtagat tatataaatg ctcatggaac ttcaacttat tacaatgatt
     8941 tatatgaaac tatggctata aaaactgtat ttggagaaaa ggcatatgac ttatgtgtgt
     9001 catcaacaaa atctatgact ggtcacttat taggagcatc aggtgctata gaggctgttg
     9061 tttgtgctat gagtatagaa gatagttttg tgcctccaac tataaacata caagaagttg
     9121 gtgaagattt ggatttagat tatgttccaa atcaaggtaa agaaaaaaat attagatatg
     9181 cactatcaaa ttctttagga tttggtgggc ataatgctac aatagtacta aaaaaatatg
     9241 tataaataaa tattaaatat aaaactaaaa aacaagcact tgttttaact gtataaattt
     9301 atattagctt aaatttaaag tctcctaaat tattttagga gattttttta ttaagattta
     9361 agtctaggat atgttgtaaa tcattttgat atattgtatt attaattatt aagaggttat
     9421 ttatatatgc aagttttcat tctacaatat acaaaaggag gactaaaatt ttgaatttta
     9481 gactaccaaa gaaaaggtta cccaaaaaga taatttttat atgtataata cttattagta
     9541 ttattttgtt tataaagtat gaccaaaatg gattgaaaga aagagaaatt ataaataagg
     9601 gaaaatatat gtctgaaagc cttgtggcag ataaggagta tgatgaagca aaaaaagtgg
     9661 ttaagacttc ttttgaatct attccagaaa aaaaatacaa taaagtatat aatgaagttt
     9721 gggatatgtt aaagactatt tcatatgttc cagatggaac gaagatagtc attgattctt
     9781 tagaaaagat gagagaatca gatgtgaaat tatctgatga atgtagattt aatatagaaa
     9841 aaagattagc atcagtgtat ataatggata ataattattc taaggcagta gatttaactg
     9901 taaagtctat aaagttggct gagaaattgg ggaataatta tgaaaaagca agactagatg
     9961 ttgatttggc gagcatattt ttaaagatag gtggctatga aacaggagag aaattaataa
    10021 aggattcttt taaaatagat attgatgaag gtgaaaaaaa tggaatggtt agattatatg
    10081 ctattataaa tctagcagaa atatatgtag aagagggcga atatgataaa gctattgaaa
    10141 taagtagcag gataaaagat tataaaaagt ttgtaaatac ggataattac aatgattttg
    10201 atataatggc ctctataatg cagtcaaatg cgtatgtggg caaaaataat atacaaaagg
    10261 caaagacttt tttagaaaaa gctgattatc ttataaaatc agatagaaca gtttatatat
    10321 tagataaaga tatgtactat tatatggcaa tgggaaactt agaatataaa agcgaaaatt
    10381 ataattctgc aatagataat tataaaaaaa gtttagagat atctactaaa agaaagttaa
    10441 cccaggagaa aataaaaaat ttaaataaga tattaaatat atatgaaaaa caaggaaata
    10501 tagaatcttt aaatgagtat caaaagatgt taataaatga atataaagag aacaaaagta
    10561 taagagattc agagactagt ttctatataa ttgataaagt atcaaacgaa agtaagctat
    10621 ttgaaaaaac taaaaaagaa ataaaatatt ataaaatatt atttacagta attttaattg
    10681 ctatattagg gtctactttt ttatacaacc gattgaagta ttttaaagca caaaatttac
    10741 atgatggtct tacaaatgtt tataatagaa aaagttttga tattatgtat gaaaagtaca
    10801 gagagaaaga tgataatttt gcacttgtga tgatagatat tgataatttc aagctcataa
    10861 atgataatta tggacataaa tttggtgaca ctgttataaa gggaataaca aataccattt
    10921 gtgttatgtt agaacaagat gataaagtct ttaggtacgg aggagaagaa ttttctgtat
    10981 taataagaaa taaatctggt gatgaagtag cagatataat tgacagtata agggttgcaa
    11041 ttgcaaataa aaagtggaat gatgatgtga ctgtgactat aagtgcaggt gtagctcatg
    11101 tttcagatag caaagatgta ctagaagaag ctgataaaaa tttatataaa gcaaaacaac
    11161 ttggtagaaa taaagtagta tataagtaat tatatactat ataaataaga ggtataaata
    11221 tgaaacaatc aatagctata gtaactgata aaataactaa actatcatct ttcttagaag
    11281 aaaatatacg tttggtttta ggtaattata ttgatataaa ccactattat ctggaagttt
    11341 taaaagagaa tgataaaata caaggtgatt ttgtactagt aatgaatgat gatagattaa
    11401 acagtatgag aaagcattta gtacaagata gtaagattat agtgataagg agaacactta
    11461 aagaaaatga aatatatgga ttattttcaa taccaaatgg aactgaagta ttggttgtaa
    11521 atgatacaaa agaaactacc ttagaaacga taagcttatt ttacaaaata ggagtaaaaa
    11581 atttaaagtt tactccatat attgaaggaa aaatttataa aaatatagac atagctataa
    11641 cacctggagt aaagggaaaa gtaccaagtt atataaataa agtaatcgac cttggaaata
    11701 gatatattga tatatctacc tttatagaaa taataaatgg tcttagaata gatgttaaag
    11761 aaatacgtaa aaatttaatg gcatattctg agagtttaat aagtttagat aatggagtta
    11821 aagataatta taggcaactg tttttaaaaa tagaagaaca agatgttata ttgaatctat
    11881 caaaagatgg aataatattt acttcagcag atggtataat aaacacattt aataaagaag
    11941 ctttaaaaat tttaggtata aatgaaaatc cacaaggcaa aaacatagaa gatatcattt
    12001 ctgaagattt aaatatttta cttgaagaca aagaaataat tgatgaagtg gtatttacaa
    12061 ataaaaaata tataaatgta aataaaaaaa gtattttttc tatggggaat aaagctggga
    12121 tatattataa cttacaagaa ataacgtata taaaaaaatt agaacaaaat cttactaata
    12181 aattaagaga acaaggtcag atagcaagat atacatttaa agatataaaa actaaaaata
    12241 aaaatatggt aaagtgtgta gaattggcta aaaaaatatc taaatcagac ctttctgtat
    12301 taataatagg agaaagtggt actggtaaag aattattatc acaatcaatt cataatgctt
    12361 ccaatagaag taatcaaccg tttatagcag ttaattgtgc agcagttcca gatagtctat
    12421 tagaaagtca actgtttgga tatgaaaaag gctcttttac aggagcttta agagaaggaa
    12481 aaaagggtct atttgaactt gctaataatg gaactatatt tctggatgaa attggagata
    12541 tgcctccatt gctacagaca aagttactaa gggtattaca agaaaagcag gttatgccta
    12601 taggttccca taatgttata aacatagatg ttagggtcat agcagcaaca aacaaaaact
    12661 tactaaagat gattagagaa ggaaaattta gagaggacct gtattataga ctaaatgtat
    12721 tgccaataga tgtaccatca ttgaggaata gaaaagaaga tataataaca cttatgaatt
    12781 tctttttgaa aaacaatata agactttcgc cagaagttat aactatttta gaaaaatata
    12841 attggccagg aaatataaga gagttacaaa atgttgcttc ttatgtaagt ctaatgtgtg
    12901 atagtatggt ttttagagat gacttaccac catatataag ggtagaatgt gctaacaatt
    12961 atgaagatgg atttggttat acaagaaaag aatttgagga aatactgagg attctatatg
    13021 aaagaagaga gtcatcctct ggaattggaa gagggtttat aatcgaaaag cttatacagg
    13081 aaggtattga gatttctgaa agcaaagtta gaaaggtgct atcttattta agtgaatgtg
    13141 gatacatatc atctaaatct ggtagaggag gaagtcaaat aacctcagag gggataaaac
    13201 tttataataa tataaattaa gctaagtatt tgatattgaa atcacatatt ttgaatttag
    13261 atatttaaat aataataaac ttttatattt atagagatta atttatatta tgtcagaaag
    13321 aatattgtaa tttataatta aatattaata ggtttttaaa ataggattag ataggtaata
    13381 ggttaagtta gaataaccca ttacctattt ttatttgtaa gaaaagtgta catagaatta
    13441 gaagtaaaaa atacaactaa taaaactatt gaaaatacta gataaataat aaataaaaat
    13501 aattatagat tttggcatac atattgctaa ttatagagat aagacgacaa aataattggg
    13561 aggtttaatg atgaaataca aaacaacagg gacttgtgct acagaaattg aatttgaagt
    13621 aaaagaaaat aaagttacaa atgtaaactt tataggtgga tgtgatggaa atttaaaagg
    13681 gctaaaagta ttagttgaag gcatgaatat agaagatgta atacaaaagt taaaaggaat
    13741 agagtgtaaa acaaagccaa catcttgccc agaccaactg tctctagcat tggaaaatta
    13801 tatgaatata aagtaataca taaaacaatc gattagttag gagtttaatt atgaaaccaa
    13861 taatagggat tttaggaaat ttaataataa tggaaaatgg tatgtttcca ggtcttgaaa
    13921 ggtcatatgt aaataatgat tatataaatg cagtgctaaa aggtggcggt agtccagtaa
    13981 taattcctgt aaatacagat aaagaagtta taaaaaaaca gattgaaatg gttgatggag
    14041 tcttaatatc tgggggatgg gatatcaatc ctcaactgta tggagaagaa acaagagaag
    14101 aaacgacatt tatatatcca gaagtggatg aatttgattt aattgcaata agtatagcat
    14161 tagaacttaa aaagcctata ttaggtgtat gtaggggact acaaatttta aatgtaagtt
    14221 taggaggaac tttatatcaa gataataatc ttatagaagg aagttatata aaacatacac
    14281 aatcttctaa aagacatgta gctactcata aagttgatgt taaagaagga agtattttag
    14341 agggaatttt aggaaaacaa ttacttacaa atagttatca tcatcaaagt gtcaatcagc
    14401 ttggaaaagg attaaaagcc atagcatact caaaagatgg tataatagaa gctattgaga
    14461 aagaggatga aaattttgta gtaggagtac agtggcatcc agaaatgatg gtagattact
    14521 gtgataaaat ggaaaaacta tttaaatatt ttataaatat ttgttcgaat ttataatata
    14581 ccttgggggg attgaacatg aacgaaaaga acaaaatggg attaataagt attatacttt
    14641 taggtattaa tgcagtagta ggagctggag tttttctatt accaggagat gcaatgaaat
    14701 catttggtgt agcaagtata tttgtatata tatttgatat gttgttagtt ttatctatgg
    14761 cattctgttt tgctgaggtt gcaggtaaat tcaataaaaa tggtgctgcc tatgtatata
    14821 caaaagaagc ttttggagat ttttgtggtt ttgaagtagg tcttatgaaa tgggtaatag
    14881 gatgtatttc ttggggagct ttaatagtag gttttcctac atcattatca gcagtatggg
    14941 ctccagcagg tgaaccacat atacaaaaaa ttataattgt agctatgata gttgggctta
    15001 caattataaa cttattaggt gtatctctat caaaaattgt acaaaatgtt ataactgtag
    15061 gtaaactaat tccattaata ctatttatag gaataggtat attttttata aaaggagtta
    15121 attttacttc ttcaacaatg gtacctccag gagctggagc aacagagttt ggagcagcag
    15181 cacttttaat gttttattca tttacaggat ttgaatctat agcagttgca gcagaagata
    15241 tggaaaatcc acaaaaaaat ataccaatag caattataag tgtaatagta attgcatcaa
    15301 taatatatat attaaatcaa gttgtatgtg ttggtatact aggagattcg ttatctagta
    15361 catctacacc agtggcagat gctgcaagaa tatgctttgg aaatatggga gctggattgg
    15421 ttacctttgg aacattggtt tctgttggtg gaatttgtat gtgtggtgct tttgtaaatc
    15481 caagaagttg tgtagcttta gctgatgata aaatgttacc gagaatattt gcaagaaaag
    15541 ataaaaaagg tacaccatat gtagcgataa tagctactat gttaatcact ataccaatag
    15601 ctctatctgg aagttttgct gaattagcag caataagtgc agttgctaga ttcatacaat
    15661 acataccaac atctttatcc gtattagtgt ttagaaagaa aagaccagaa ttagtaggta
    15721 cttttaaaac tccttttgga gcagtgattc ctctaattgc tgtatgtgtt ggaacatggt
    15781 tgttattcca agcatctatg catcaattaa ttatgggatt aggagctttg gcaattggag
    15841 taccattata ctttataatg aagtcttata atagaaaaat ctatggtgaa aatttaaaga
    15901 aaatagttta attatgttat aacaatttat tgagttaaaa ttagacattg gcagaaaatt
    15961 aaatacaaat aagtatctac aaggctatat taaaatatta ttaatttttt attttaatat
    16021 agccttatat tgttatcaat aaatgaaaaa tattgtaaca acagaagaac aatagtatta
    16081 tgtttataga caaaaaactt attaggaggt aaatttatgc caacaataac attaaaaaat
    16141 ggtgtagacg tacttattag agaaggtgta agagaagatg ctcaaagcat tatagatttt
    16201 tataatgaag tgggtggaga aactcatttt ctgtcatttg gaaaggatga atataaaata
    16261 tctttggagg aacaagaaaa tgctatagaa tcagcaaaag catctgataa ttctgttaaa
    16321 ctgattgcat ttatagatgg tgaaatagtt gggattgcaa cgattgattc taatcaaaaa
    16381 gcaaaaggaa agcatgttgg agtattagga attgttgtaa aagaaaaata ttggggaatt
    16441 ggattgggta aaaggcttat gttagacctt atagaatggt gtaaatcaaa tggaataacc
    16501 aagaagataa ctcttgtcac taatgaagaa aattataatg ctataggatt atacaaaaaa
    16561 gttggatttg aagtagaaag catactaaag aaagaatgtt attataatgg tgtttatact
    16621 gatttaatag gaatgtcact tttattggga atataattag tgtacatttt atctcgaaaa
    16681 aagtatatta agtatggtat aattaaaaaa gaatataact taatataatt ttggaggacg
    16741 aattatgaaa aatctgtgta aaatatcaga tgattattta aacagcaagc ttaagtattt
    16801 aaagttatta tcaaaacaat atccaagtat atcaaaagca agtacagaaa taataaattt
    16861 agaggctata ttaaatcttc caaagggaac agagcatttt ataacagatg tacatggtga
    16921 atatgaacca tttgtacatg tattaaaaaa tggttctggt gtaataaaga gaaaaataga
    16981 agaattgttt tcaaatacaa taagagacag cgaaaaaaaa atgttagcaa ctcttgtata
    17041 ttatcctgaa caaaagttag acctaataat taagcaagag gaaaatatag atgattttta
    17101 tagaataaat atttatagac ttatagaact ttgtaaatat gcttctagca aatatactag
    17161 gtctaaagtt agaaaactgt taccagaaaa ttttaaatac ataatagaag aacttttgca
    17221 tgagcatgtt aaaagtgaac ataaagaaga gtattataaa agtatagttg aaacaatagt
    17281 tgacatagga atagctaagg agtttataat tgctatttct acagttatac aaaaattggt
    17341 tgtagataga cttcatgtaa taggagatat ttatgataga ggtccaagac cagatataat
    17401 tgtcgataag cttattgaac atcattgtgt agatattcaa tggggaaatc atgatatatt
    17461 gtggatgggt gcagcctcag gtgaaaaaac ttgtatagca aatgcactga ggatatcagc
    17521 tagatatgcg aatttagaca ttgtagaaga catatatgga ataaatctat tgcctttagc
    17581 cacttttgct atagaaatgt ataaagatga cccttgtaaa gaatttattc caaaggttaa
    17641 tgaccaaagt gtaacaacaa cagaaaagtc tttaatggca aaaatgcaca aagcaataag
    17701 tataattcaa tttaagcttg aaggtgaggt tatcagacga agacctgaat ttgaaatgga
    17761 acatagactc ttgcttaata tgataaacta tgatgaaggt acgattaatt taaaaggtaa
    17821 aacatataaa ttaaaagata cttatttacc tacaatagac aaaaaagacc catataaatt
    17881 aactatggaa gaaagaaatg ttattgataa attagtatct tcatttagag gtagtgaaaa
    17941 actacaaaaa catgtttcat ttttgttttc taaaggaagt atatatttaa aggctaactc
    18001 aaatttactg attcatggat gtgtaccgtt aaatgaagat ggaagcttta tgtctatgaa
    18061 tataatggga aaagagtata aaggtaaggc tcttatggat aagatggagt ctctagcaag
    18121 agaaggattt ttctttaaag ataaggcaga agaaaaactg tatggcatgg atattatgtg
    18181 gtatttatgg actgggaaat gttcatcatt atttggtaaa gatgatatga ctacatttga
    18241 aagatacttt atagctgaaa aagagactca taaagaaaat aagaacccat attttaaact
    18301 tagagaaaat gagatggctt gtaaaagatt atttgaagaa tttgatttag aacttgatga
    18361 atctcatata ataaatggtc atgttcctgt ggagagtaaa aatggagaga gcccaataaa
    18421 agctaatggt aaaattctcg ttatagatgg tggtttttct agggcttacc aaaaaactac
    18481 tggtatagct ggatacactt tgatatacaa ttctagaact ttgcaattag tatcgcatga
    18541 accatttaat tctgctgaag aagccattgc aaatgaaagt gatatcttat cgacaactgt
    18601 tgtagtagag cataaggcaa agagaaaaat ggtgagagat actgatgaag gaataaagat
    18661 acaagaggaa atagaagatt taaaactact tttaatggct tataagaaag ggctaataaa
    18721 agaaatgtag atgttataga ggcacttcat gattgaagtg tctttttgtt aatacttatt
    18781 aaatatatta taaagattaa taatagtagt ttatattata cttactaagt gaatccaaga
    18841 taaatgggtt cacttttttt atttataaac attattaaaa aaatatagat gttttggtta
    18901 tattccttgt cctttataaa tagaattata taaacaaagg aggaggacaa gagatgaata
    18961 aactttctga tgaaataata aactctcttt ctacaactat aagagaaaag gtagaaaaag
    19021 tctcaaacaa taatctgaac atagaagaaa ttaggttacg ctcacaaaaa ccattgatac
    19081 taaatgcaaa ctctaaagat tatttttaca atcaaaaaac tatgacactt gatttaaatc
    19141 aacaaaactc atatgtagta acaagagaag atgtagagca aacttttcaa ataatatgta
    19201 aatattcaat acattcattt atggatgaca taaaaaaagg attcataact ttgagaggag
    19261 gtcatagagt agggttagtt ggaaaagcaa tagtagaaga tggacaagtc aaaaatataa
    19321 agcatatatc atctttaaat ataagggtat caagggaaat tattggatgc tcggataaga
    19381 ttttaagtca tatcataaag ggaaaaaatc agattaataa tactttgata atatcaccac
    19441 ctcaatgtgg aaaaacaact ttaataagag atatagtaag aaatttaagt aatggtaatg
    19501 aagattatgg atttaaaggt ttaaaagtgg ctttagtaga tgagcgtaat gagatagcag
    19561 gagcttatct aggtgttcca caaatggatg tgggaataag gactgatata atagaaactt
    19621 gcccaaaaga cttgggtatt acaatgcttt taaggtctat gtcaccaaat gttattgtga
    19681 cagatgaaat tggaagtgaa aaagaaataa aggcattata cacagcatta aatggaggta
    19741 taggattaat aactactgtg catggagatt caatagagga tatacaaaat agaaaagaat
    19801 taaatagact tctggataaa gagttattta aaaaggttat aattctttct gcaaaaagag
    19861 gagcaggaac aattgaaaaa atttatgatt tagaagaaaa gagatggtat tttgcaaatt
    19921 aaaataatta ttatagcttt cttgatagga agtagttatt tgataggtga acaaatatac
    19981 aaaacttata ctcgtagaca taaacaatta aacgatttaa taagagtttt agaaattttg
    20041 aggatggatt tatcttttgg actttataca ttagaagaaa tctttaatag gataggtgga
    20101 aataaagagt tttgtttttg gaaatttttc tatcaaatat cagaaggact tcacaatgaa
    20161 caaagtaaaa ctttggaaat aataatatca gaaaatattg atgtcttaag taaagaaact
    20221 tatctaggca ataaagaaat tgaggaactg aaaaatctaa tacttacttt agggaaaagc
    20281 gatatagagt cacaacaaag aatgatagat ttatctatag aaaatttgaa aaaacaaacc
    20341 tatgagacaa aggaagatat aaacaaaaaa ggcgtattgt ataaaaaatt agtgacattc
    20401 ataggtatag gtatatgtat tatattgatt taatatgggg aggtttatta tggaaatatc
    20461 attgatatta aaggttgcag gtgtcggtat tctaatatca gtattgaata tgatattgga
    20521 aaaaacagat agaaaagatt gggcaggtct tactacatta gcaggtgtaa taatcgtatt
    20581 gggtatggta ataacagaaa taagtgactt gtttaatact gtaagaacaa tgtttcaact
    20641 ttactaaaga ggagggagta atttggaaat aatgcaatta ataggaattg caatcatttc
    20701 aactacactc tgtttagtaa ttaaaaaaga tagaccagag atagcaaatt tcatagctat
    20761 aataactgga gtaataatac tattgtcagt tatgtttaag ctaaatttta tagtagatag
    20821 tatacaagat ttggctaaca aggctaacat cccaactatg tatatatcat taataataaa
    20881 attaattggg atagcatact taatggaatt tgcgatacaa ctttgtaaag attgtgggga
    20941 aggaaacatt gcttcaaaac tagaatttgg aggtaaaata atagttatgt caatgtcttt
    21001 ccctatactt ttgtccattg tagaaatggt ggtgaatata attccataga tgtgtatctt
    21061 ggaatgaata taagtatatt agagagcttt cgttgtattg aggtttatag agtgaagaga
    21121 ggcatggttg cttatgaaaa aaagattttt accaatgatt ataggttttt tatttacttt
    21181 cttttttgta aatatctttg ctattatgat atttgctaat gaagtaccaa gtagtgaaga
    21241 taaagaatat ggtgaaacaa aaaatagcat agataagtat atagatggtc aattagacaa
    21301 gctagatata aatgagattc aagactatat aaataaagaa atagttatta atgatgttaa
    21361 tttaaaatca tttgtaaaag atttaattag tggagaaaaa aatatcttag atttattcaa
    21421 taaagatgga ttgaagatat tgatgtttga tgaatttaaa gcaagtttaa aggtagtagc
    21481 agtaattttg gtactggctc tgttatcatc tattttaaag agtctggaaa actctttttc
    21541 atcaggtgca gtaagtcaaa tagcaacata tataatattt atcacaatgg tatcacttac
    21601 acttattggt tttaaagatg tattacagat ttgctatgat gcaatagacc atactgtagg
    21661 tcttatgcaa gttataatgc caatattaat aacattttta cttttaattg gattcccaat
    21721 aacgtcgact actttgaatc ctatcttcat aggaggagta acatttataa atgtattttt
    21781 taaaaatttt ctatttgtat ctattactgt tgcatttgga attttaataa taaacaattt
    21841 atcaaaaaat ataaggctaa agagattttt ctcctttgta aaacaaataa attatgtttc
    21901 tattggagct atgtttactg tttacttagg tcttgtatcc atacaaggat tgtatgtaac
    21961 cagttttgat aaattcagtg taaagactgc taaatttgct ataggtaatt ttattcctgt
    22021 tgtaggtgga tttgtatctg actctgtgga tattttatta tcttcatctc agcttataaa
    22081 aaatatattt ggaggaatag gacttatctt acttgttgga atttgcttac ttccagtaat
    22141 aaaaatttta tcagtaatag tagtgtacaa attagcagca ataattgtag agcctgttgg
    22201 agaggatgga atatctaatt ttttaaatga agtggcaaat ttaatgataa taatgctagc
    22261 atcagtaatt gctataacag taatgttctt tgtaactgta gctatcttga cctcgataag
    22321 tgtcgtaagt caagggtaat ttatatatca gtgaaaaata attacattta atctaatgtt
    22381 tttagagagg aggatgctat gttagagggc ataaaggcat ggatagttag tgttttgata
    22441 ggagcattta tagtaaatat agtagatatg attttaccaa gttctaagat aaaaccttat
    22501 gtcaacctag ttttaaactt tatgtttgta tttattgtaa taactccagt agtaggattt
    22561 ttttcaaaag atatgagttt agaagataga atattaaaat ctatgggaaa ctacaacaag
    22621 cagtatgtag atagtacaaa tgctttggca aaagagactg gaaataatag tctatccaag
    22681 ggatatgagg atgggttaaa agaagtactt aaattaaaac ttgatgaata tggttatgat
    22741 ttagaagata tagagcttaa tggggcaaat ataaataata taaaaataaa agaaaagaat
    22801 aatagtgcaa aaagtaataa cagttccaat gaagaaaata aaaataatag tactaaaaga
    22861 gaggaagaaa acataaactc taatgacaaa gaaaattcta aacaagtctt caaaaaaggt
    22921 acagagtatg ggttgaacct aaatgaagaa aaattaaaaa acgacttaat aaaggtgctg
    22981 gatgtttcta tagaagatat acaaattgat aaataggagt tgggagaatg ttgaaaaact
    23041 taaatgacaa agataagaga aaggtatatt cactaataac tatagcagga atatgtgtgg
    23101 tttcattagt attattatct tgttttccta gtagcaaaag cgataaacaa gttggaaaaa
    23161 cagagactaa taaaaatgct gaaaagcaag tcactaaaga acaagaaaaa gatgatttag
    23221 agtcaaaatt aacagcaata ctatctaaaa ttgatggtgc aggagacgtt gatgtaatgg
    23281 ttacatttga atcaagtgaa gaaatacaac ctgcttttaa ttcaaataat acaacagaaa
    23341 caacagagga aaaagatgca caaggtggag aaagaacagt tacgacttct agtgaaaata
    23401 aaacaatgat aacttcaaat tcaagtgacc ctgtagttat aaaaactaca gagccaaaga
    23461 taaagggagt gatagtggta gcaagtggag caagtgaccc aagtgttaaa gagacacttt
    23521 atagtgcagt acaaacatca ttacaagtag ctggtcatca agtagaaata tattctaaat
    23581 aaatacatat aaccgggggg ataaatgaat gaagtttaat tataagggaa gaggatttgt
    23641 aataataact ttaactgcaa tgttagtggt agtaggaaca gtgaattatc aactaagtaa
    23701 gaaatcttta ttagaaacat caaaagagtt taaggcatat gaagaagcac agttgcaaaa
    23761 aaatactgat gagagtgata gtagtaagac agaggattct agtaatgtag ataaacaaga
    23821 tggtaaggaa agtgctgata ttgatatagt tgatagcaaa gctagtaaag taaaagaaaa
    23881 ggcaactgag acaagtaagg aaataaaagc tcaattatca tcagagaaaa atatgaaaaa
    23941 ggcatcttat attttagata tgaaaatgaa tagagaaaaa caaagaaatg agttagttca
    24001 agatttaaat gaaatgataa ataatccatc tacaacagaa gaatctagaa aagaagcttc
    24061 taatatgaaa ttaaatatag ttaaaattca agaaaaagaa cttcaaatag aaaacctttt
    24121 gagtacaaaa gggtatgaag aagcgttagt ttatataagc gataacaaag ttaatgtagt
    24181 tgtaaatgaa gctaaattag aaaagaaaga tgcagcaaaa atatttgatt tagttgcaga
    24241 acaagccaat gtgaagtatg aaaatattaa acttacaaat aataatagta ataagtaaag
    24301 tataaacctc agaattaact gaggttattt tcttgcaaag tagacttgta tttggtatta
    24361 ttatacttat aaaaatagtt ccttaaaatc aggaggtaag ttttaatatg gaagataata
    24421 aatttggaca agtaaaaata tctaatgatg taatagctac aatagctggt ttagcagcat
    24481 tagaagttga aggcatagaa actacagcaa cattaacaga taagttgtta aaaaataatg
    24541 gagtaaaaat acaaatcgaa gaagaggatg ttaatttaga tgtaatggtt acgataaagt
    24601 atggaatgtc aataccagat acagctttta aagttcaaga aaatgtaaaa aatactgttg
    24661 agacaatgac aggactgaag gtttctcaag taaatataca cattcaagga atcagcttta
    24721 agaaggataa agttgataaa gaagaagcaa aagcaactaa gaaaaattaa tattagccct
    24781 ctgaaaagtc agagggtttt ttgctggtaa ttgattttat atggataatt aaacttaaag
    24841 gagaattttg attgatgaaa aaagataggg cacaaaagag tacaacaaga gaatatataa
    24901 tgaaacttat ataccaaata aatattaata aagaagattt tgaaacttta gaagataaag
    24961 tagataattt tttaaaagat aattcagaac atattataaa tagatataaa gaacttgcac
    25021 ttcaatactc aaaaaataca aatttaaagt tagaagatac tgaaattgaa gatgttatag
    25081 acaaaaaata tataaataca gtatgcaaag cattgaaaga aaatcatgac aaaatagatg
    25141 agttaataaa taagcatgct aaaaactgga cagtagatag aatgccaaag gtagatgttt
    25201 ctatacttag attgtctgtg tgtgaaatac tttatttaga cactcctaat aaagtatcaa
    25261 taaatgaagc agtagaactt gcaaaaatat attgtgatga taagtctcct aaatttataa
    25321 atggtatatt gggaagtgtt gttgatgaaa ttgggaaata atataataat tggaattgat
    25381 actagctgct atactacttc tatagcagct atctctttag ataagaaagt tatattcaat
    25441 gaaaaaataa tgttagaagt aagggataat tcaaaaggtt taaggcaaag tgaagctgta
    25501 tttcaacata tcaataattt agggattctt agtgatagga taaaatcttt taaagataag
    25561 tttaatgtag aaggagtttg ctcatcaaaa aaaccgagac ctgttgaaaa ctcatatatg
    25621 cctgtattca atgtaggtca taattttgga aaattattgt ctagtatata tggttgtagg
    25681 ttttatgaga ctactcatca agagaatcat attgaagcaa gtttattaaa tagtaaatta
    25741 aaaaataata ataaatttat ttctgttcat atgtctggtg gtactacaga gatactttta
    25801 acaagcaaac aagatagtca tcacaatgta tgtgatacta atttaggtaa aattgccaaa
    25861 ataagtatta aaaaagatga taaaagtaag ttatacaata attttggata taatatagat
    25921 ataattggag gaagtaaaga tattagcttt ggtcaactta tagatagagt aggaattaag
    25981 cttggatata aatttccttc aggaaagtat ttggatgaaa atgctttaaa ttgtaatctt
    26041 aaaatagaaa gtggtctgaa aacttctgta agagatgggt atatgaattt atcaggatta
    26101 gaaaatcagg taaataagat tataaatgat aatggagata atactaatca aaaagaatat
    26161 atatctaaat tggtattaga ttcagtagtt agaaatatgt ttaaatcttt agtgtattta
    26221 tgtgaaactt ataatgtaaa tgaagtagta tttgctggtg gagtttctgc aagtaagtat
    26281 attcttagag aattaagcat gaagttaaga aaaaagcata tagaagctta ttttacagaa
    26341 ccacaatatt caactgataa tgctgtcggg tgtgctataa taggattgaa taacttttta
    26401 ggagaaagag tatgaaacta agagctttag atataagtga agcaaactca tatattaaaa
    26461 gaattttaat aaacgaccca atactttcta atcttaaagt taaaggagaa atttctaatt
    26521 ttaaggttca tagtagtggg aatgtatatt tatcacttaa agatgaaaca tcaaagttaa
    26581 actgtgtaat ttttaaaagt aattttaatc gcaatttaaa attagataat ggtgtaaaaa
    26641 ttatagctaa tggatatata tcagtctatg aaagagatgg tgcgtatcaa ttatacatta
    26701 atgaaattga aatagaggga ataggaaatt tacacataga gtttaataga ttaaaggaaa
    26761 aacttaataa agaaggatta tttgacccta aatacaagat acctatacct aaaatgccaa
    26821 actcaattgg cgttataaca tctccaacag gtgctgttat aagagatata ataaatgtaa
    26881 taaaaagaag atatccgaaa gttaatataa agctttatcc agtaacggtt caaggagata
    26941 aatcagctga agaaatctgt gaagcaatta gatttttcaa tcatatgaag aatgttgata
    27001 cacttatagt tggtagaggt gggggttcga tagaagaact ttggtctttt aatgatgaaa
    27061 tggtagcaag agaggttttt aattctcaaa ttccgataat atcagcagtt gggcatgaaa
    27121 cggattttac tatttgtgac tttgtgtctg atatgagagc cccaacgcca tcagcagcag
    27181 ctgagattgc tactccatca ttggatgata taaactataa acttggaaac ataaaaagta
    27241 ggatgagtaa gtctcttaca aatcaaatag agctagacca atataggtta gaaacagtat
    27301 ttaataagat aaataactat ttagattcgt acacaataaa agataaagtt atacaattag
    27361 acaaaatata tgataaaata atttttggaa tagaaaataa tttaaaatta gaagatgaaa
    27421 aattagtaaa aattggagca ttactccata atttaagtcc attagctact atggatagag
    27481 gttatagtat aactcaaaaa aatggaaaag taataaatag tataaaagga ttaaaaataa
    27541 aggatagtat agatatagta ttaaaagatg gaaatttaga atgtatgata gataaaattg
    27601 aaaataaaga gggatagtat gaatttaacc tacgaagaag cttataaaag attagaaagt
    27661 attttaagtg aattagaatc taaaaatgct agcttggatg aatctttaag cctatatgaa
    27721 gaaggtataa gcctttataa acattgtaat aagcttttag atgatgctaa attgaaaata
    27781 agtaaattta atcaattggg aatagaagaa gactttaaaa tagaggagga ataaaattgg
    27841 aatttaaaca atgtctaaaa gaaaaagcaa gttttgtaga aaaagtactt aaagaatata
    27901 tgcctaaaga agaagggtat caaaaaactg ttattgaagc tatgaactat agcttaagtg
    27961 ctggaggtaa aagattaaga ccaatactta cattggaggc ttgtaaaata gttggaggta
    28021 atgaagatga agctattcct tttgctattg caattgaaat gatacataca tattcactaa
    28081 tacatgatga tttgccagct cttgacaatg atgatttaag aaggggaaga ccaacaaatc
    28141 ataaagtata tggagaagct atggggattt tagcaggaga tgctttgtta aactatgctt
    28201 ttgaagtaat gcttgcaggc tcaatcaata aagaaaatcc agaaaagtat ctaaaagcta
    28261 taaatgaaat tgccaaaggt gctggtatat atggaatgat aggtggtcaa gtagtagatg
    28321 tagaaagcga aaataaacaa attggaaaag aaaaattaga ttatatacat atgaataaaa
    28381 ctgctgcaat gatggtaggc tgtatgagag caggagctac tataggtgga gcaaattctg
    28441 aacaaatgga agaaataact aaatatgcaa aaaatatcgg attatcattc cagatagtag
    28501 atgatatact agacatagta ggagatgaag ctaagttagg taaaaaggtt ggaagtgata
    28561 tagaaaatca taagtcaaca tacccatctc ttttaggttt agataaatct aaagaaattg
    28621 cacataattt gattgatgaa gcaaagaaaa gtatagaaaa attatctgat gatgtagatt
    28681 ttttaaaggg attggctgaa tatataatag atagagaata ctaaaatata cagctaaaat
    28741 cgaggaggga aaaatggatt ttttttcgga gatttttaac aatggggctt tgggaataag
    28801 tctgattgct tgtttcttag cacaatttat aaaaatattt actggtaagg aaaaaagaat
    28861 tgagttatca agaatactta tttcaggagg tatgcctagt tcccatagtt cttttgttac
    28921 aagtttagct acagtggtag gtattgaaaa agggtttaat tctactgatt ttgctataat
    28981 taccgtgctt gccttaatta taatgtatga tgcagcaggt gttagacggg ctgttggtaa
    29041 acaagctact atattaaatc aaatggtggc agatatacag catggaaagc atatagagca
    29101 gaagaaatta aaagaattaa taggtcatac accactagaa gtttggtttg gagctttact
    29161 tggaatagta acagctttaa tattgatgta aattgaaaat ttacagaata aaggtgagga
    29221 taatatgtat aaatatttag ataaagtaaa ttctccaaag gatataaaaa atatgagtat
    29281 agaagaaatg gatttacttg caaaggatat aagaaagttc ttagtaaaat ctgtttcaaa
    29341 gacaggagga cacttagctt ctaatctagg agtggttgag ttaacattag cacttcataa
    29401 agtatttgat agccctaaag ataagattgt atgggatgta gggcatcaat cttatgttca
    29461 taaaatagtt actggaagaa aagattgttt tgtatctttg agacagttta atggactaag
    29521 tggttttcca aaggagaatg aaagtcctca tgatattttt gatacaggac atagcagtac
    29581 atctatttct atagctacag gtattgcctg tgctagggat ataaaaaaag aaaactatag
    29641 tgttatatct gtgataggag atggttctat aacaggaggt atggcacttg aagctttaaa
    29701 tcaattagga tatatagata ccaatatgat agtaatcctt aatgataatg agatgtccat
    29761 agataaaaat gttggaggaa tgtctaaata tctgtcaagt attataagaa actcaacagt
    29821 tgagaaaatg acagatgaag ttgataaaat tttaaatgtt acacaaacag gtgaaatttt
    29881 atctaagact gcacatagat ttaaagataa actaatgtat agcttttctc ctcaggactg
    29941 ttcatttttt gattcattag gtataagata ttatggacct atagatggcc ataatactaa
    30001 agaactaata gatatattga gaaaagctaa acacaaaaaa gggcctgttc ttttacatgt
    30061 aattacgaaa aaaggaaaag ggtacagatt tgcagaagaa caacctgata aatatcatgg
    30121 agtatcaaag tttgatataa agacaggtgt tacatctgca aaagttaagt ctatgtcaat
    30181 tagtgttgga gaaaaacttg ttgatatggc taatagtaat gaaaatatag tagcaataac
    30241 agctgcaatg ccatctggta cagggttaaa cctgtttgaa agtgcatatc caaaaagata
    30301 ttatgatgtt ggtatagctg aacaacatgc aacaggattt gcagcaggtc ttgcaaaaaa
    30361 tggtatgaaa ccttactttg ctgtgtactc atcatttttg caaagggcat atgaccaagt
    30421 tattcatgat gtatgcataa caaaaaagcc agttactttt cttatagata gagctggatt
    30481 agttggaaat gatggagaaa ctcatcatgg tatgtttgat ttaagttact taaattctat
    30541 tccaaatatt gtagtaatgg ctccaaaaga cacaagagag atggagctta tgatggattt
    30601 gtcattaaaa ttagattgtc cactagcaat tagataccca agaggaagta gttattacct
    30661 agataaggga gagtatggag agattgtact gggtaaatat gaggtattag atgacggtca
    30721 agatacagtc atactttgta ttggaagtat ggtaaaacat gctttagagg ctaaagaaat
    30781 attatcaaga gaaggaataa atccgacaat agttaatgct agattcttaa agccaattga
    30841 tgaaggtatg ttaaaagcat tattaaaaaa tcataaaaat gtagttacta tagaggataa
    30901 tattgtaact ggaggatttg gaagtagaat aaataagttt attatagata atgaatataa
    30961 cgtaaatata cttaatatag caataccaga agaatttgta aaacatggca atatagatga
    31021 attatatgat tttgtaggat tatcgccaaa aagtattgct gataaaataa ggaaattagt
    31081 tattgagtaa aaatctaatg tagatattgt aaattaaaat ttatataaaa tatagaattt
    31141 atcaattaga ataaatatca agtgtgttac ttcaagctac tttagttatc attaaagtag
    31201 cttttaacag aaaggtaatt gtatgaaaaa aagaatagat ttattattag tagaacaagg
    31261 gtactttgaa agtagagaaa gagccaaaaa agcaataatg gctggattgg tttttgttga
    31321 taatcaaagg tgtgataagg ctggtacaga agtaaaagaa gattgtagta tagaagtaaa
    31381 aggaaatcca ataccatatg tcagtagagg tggtttaaag cttgaaaaag caatgaaaaa
    31441 ctttgatttg actattgatg gaaaggtatg tatggatata ggggcatcca caggtggttt
    31501 tacagattgt atgctcaaaa atggagcaat aaaagtattt tctatagatg ttggttatgg
    31561 tcaacttgca tggaaattga gacaagatga tagggttgtg tgtatggaaa gaaccaatat
    31621 aagaaatgtg acaatagaag atacaaagca gtttgctgat tttgcgtcaa ttgatgtgtc
    31681 ttttatatcg ttaaagttag tacttccaaa ggcaaaggag ttagtacgtc atgatgggga
    31741 agttgtcgct ttaattaaac ctcaatttga agcaggaaga gaaaaagtag gtaaaaaagg
    31801 agtagttaga gaaaaatcta cacatataga agttataaaa atgatttctg atttctcagt
    31861 cgaaaatgga tttgagattt tagggttaga tttttctcct attaaaggtc ctgaaggtaa
    31921 tatagaatat ctaattcatt tgagaaatgg aaatgaagga tatgaatttg atggtgagac
    31981 atacaataac aaaatagtag aagttgttga agcttctcat aatttagaca aataggttaa
    32041 aagggggctt agatttgatc ctcgaattat atatgaaaaa ttgtgcctta gttgaagaac
    32101 taaggttgaa tattgataaa aacttaaata tacttacagg tgaaactggt tcaggaaaat
    32161 ctataataat agatgcactt ggactttgtt taggtgataa atatgatagg tcttttttaa
    32221 gaaaaggaac agataaggga cttgttgagg ctgtattttt ttcagacaat agatatctta
    32281 aaaaaatatt agaagaaaat gatataagta tggaagatga taatttattg gtaataacta
    32341 ggttgatata ctcagatggt aagagtactg ctagagtaaa tggaaggact gttaaagtgt
    32401 ctcttcttaa agaaattgca tctacactta tagatataca tggtcaacat caaaatcaag
    32461 ctttgtttaa taaagatact catttaaaat ttctagacct ttttggagaa aatgaattgg
    32521 aagagtttaa aattgcttat aaaaatgtgt accataagta tagtgaagta aaaaaagctt
    32581 taaattgctt gacagaaaat aaagatgaga tgcaaattca acgagaaata gatttattaa
    32641 gatttcaaat aaatgaaatt gaagctgcaa atctaaataa gaatgaatat gaagatttat
    32701 taaaacaaag agaagtttat agaaatagtg aaaagatata taataatcta aattcgagtt
    32761 atagcaagtt acataatggt gagtataatg ttattgacct aataggtctt gcatctaagg
    32821 aacttaatga catatctaaa tatgacagtg ttttaagtga atatagtgat actgtagaaa
    32881 gaatcatgta tgagttacaa gacatatctg gtgagataag aaattacaaa gataatatag
    32941 actttgaacc ttatgagcta gagcagattg agcttagaat cgacgagatt aataacttaa
    33001 gaagaaaata tggagacagt atagatgata tatttgagta ttatggaaaa attaaagata
    33061 gattagatga aatattaaac agagatgaaa gagttgaaca gttaagaagc aaactgatga
    33121 atatagaaga agatttaaaa ataaaagcca gtaaattgac taaagcaaga atagaagtag
    33181 caactacttt agaaaaaata cttcttgatg aattaaaaag cttaaatatg aaaaatgtaa
    33241 tgttcaaggt taattttgaa aaaggtccat ttactttaga tggagtagat gatattgaat
    33301 ttatgatatc ttttaactta ggagaagata ttaagcctat atataaagtt gcatcaggtg
    33361 gtgagatgtc cagatttatg ttagcgttta aaaccatatt ggctgatata gatgatattg
    33421 atacattagt gtttgacgag atagatactg gaataagtgg gatagcagca cagatagttg
    33481 gtgagaaatt gagtgatata gcaaagaaaa aacagataat atgtataact catttacctc
    33541 aaattgctgc aaatgcagac actcattatt gtatagagaa agatacttca aataatagga
    33601 cgtttaccaa tgttagtaag ttaaatgaat ctcaacgaaa aaatgaaatt gccagactta
    33661 tagcaggtaa caatataaca gaaaaaacta ttgaacatgc aagtgaaatt attgagttgg
    33721 ctaaaaaatg ttagtgaaaa acaagcattt taataggtgt aaagaatttt tatagaaatg
    33781 ctttacatct attttttatg atgaaattat tttaaaatat ctagtgccta tattgaagaa
    33841 aagtagattt aaaaatagaa gaaaatttgt ataaatttgt aactttgaaa tttctaaatg
    33901 cttaagtata atattattta ttaaggtagt agtgaggggg acataaaatg aataaaaaag
    33961 atactatgca cttaattttt acaattgtaa tttttatttt attatggtat attgtggtag
    34021 cagtaagtga gattaataaa aatattgaaa gttgtagtaa taaattagat tatttgtcac
    34081 aagagattat gagtactaaa tcggatatta gtaatactat aaatgaagaa atgtcaaaaa
    34141 gttatataac aaagagtatt gacttaaaag taaaaaaaat cgagaaaaaa gagtgtgtta
    34201 ttgatgtaga tgttcaatta agtaaacttg gaaaaaatgg aaaagtattt tttatgtata
    34261 aagaagatag tgataaatgg aatgaaactg agatgacaaa acatggagaa ttatcatatg
    34321 catgtgaaat taagataaat acaggaagtg aatatgacta taaagtagtt acaagtggag
    34381 ctatatctga aagttctgat gtgcaaaaat tgactaaatc tgattatatg cctgaacaac
    34441 ccatatttaa ttctgggata agagataata gagaatactt tattgaaata gtagaaaata
    34501 gtaatctttt caatcatgag agtgaaaagt caaaaaataa agtttatgat aatattagat
    34561 tagaaaaagt agatattatt gtaaatgaag gaaaaaaaga cactatatac aaagccaaat
    34621 tagctgaagg cttagatgat ggcaaaacta ataattcaaa tagaaatcaa gtgaattatg
    34681 aagtaagttt tcctaaaagg gatattgatg acataattta tattaaagct aaacttacat
    34741 acaataatgg agtagaatat acaaaggata taactgaaga tataactatg ggattacaag
    34801 atttagaaaa ataaatacat atttaaataa atattcaaat agatttgttc aataaaatag
    34861 agtataaata aaactgtagt agttttactt atactctatt aaaaaattat aattttaatt
    34921 ccatatatct agccccttca attggattat aagtataagg ttctatatca taaaaaccaa
    34981 acttttcata taatccttgt gcacttttca tgcttggaag agtatctaat ctcatgtgtg
    35041 tatatccaaa ttttttagct tcttcaatga tttcttccaa tagtattttt cctattttta
    35101 atcctctaaa ttgatttctt acatataatc tttttaattc acatatttta ccttcaagtt
    35161 tttttaaagc aacacaacct gccaaatttt catcaacaaa tgccaatatc aatgagcctg
    35221 aaggtttttt atattttcct ggaagtgttt ttaattcatt attaaagtct tgaaaacata
    35281 agtctatatt tagagaattt gaatattcag taaatagaag ttttacgttt tcaaggtttt
    35341 ctaaatcttt ttcttcaaca aattgtaaag ttatattttg agccatttta tccgccatta
    35401 tataaacatg tttatataat gacttcacct ccttgatata tgtatatttt tcttaatatc
    35461 aattagattt taataccatt actttttcac caccatagtc aagctctcca ttaaactcaa
    35521 atccaaaatc tttataaagc ttaatagcca ttttattgtc ttcgaatata ctaagatata
    35581 gttcatcaca gttatattca tttttaagat gatttacaag aaaatctaat gatgcttttc
    35641 catatccttt accttgatat tttgaatcaa tcataaatct atcaagccaa actctatcat
    35701 cttctaaacg accatacata gcaaatccta ttaaagaatt ttcatcatat attccaacag
    35761 gtacccaagc tgttataaat ttagattcag caatagaaag tgcattgctt tctatataat
    35821 ctaactgact tttatctaca gacaaactaa ctaaatcatg ccaattattt atgtctgcaa
    35881 ttcttacatt taatttcaag atattaccgc ccttcaaact ttttgttaca atctaatact
    35941 atcatattat gtattaaaaa tcacttatta agattttaaa taaacttttt aaatgaataa
    36001 attctcagga aaaaggaatt ataaatacat aataatacag cataggagta gatggatata
    36061 tgaacaaaat aaataaaaat ttcaaaaata tttggataat attaggagct gtatcgattt
    36121 ttaccatggt tataattttt aataaaaatt gtaatgttaa taaagagact caaatagaag
    36181 cttttacaat taagaatcat gataaaaaat ttgtatatcc tatgggaaat ataattggag
    36241 taaaagcaaa tacagatggt gtattggtct taggatatga ggaagaggat gtagactata
    36301 ttggaggcat acaaatcggt gataatatag taaaaataga taataaaagg ataaaaaata
    36361 gtcaagatgt atcagagatt ttgaataaga ttaaaaaaag taaagttgaa gtgacttttg
    36421 agagaaaaaa taagtataaa acagaagtaa tagagactaa aaaagaaaat ggcaagtata
    36481 aacttggatt atgggtaaga gataaaatat ctggaattgg aactatgact ttttacgacc
    36541 ctagtatgga aaagttcaaa gcaatcggtc atgccataaa agattcggat actaatgaac
    36601 tattaaagat aaagcaagga tatatatata agccagaaca attaaaaata gtaaaagcta
    36661 gtaatgaaaa agtaggtaaa ataaaaggag attttaatga cagcaattta atgggtaatt
    36721 tctcaaataa ttcagagtta ggtataagtg gtaatattac agaaaaccat aataaagagt
    36781 ttaatgtagc aaataaagaa aagcaattaa tagaagttgg aagaccgcaa gatgtaaaaa
    36841 taggagatgc agtaattctt tttgaggata aaaacaaaaa tataacaagc tatgatataa
    36901 aaatagaaag tatagtatat gataaaggaa attatagaga tatggtaata aaagtagtag
    36961 atgacaagtt attggaatac acaggaggta tcgtacaggg gatgagtgga gctccaataa
    37021 tacaaaataa taaaattatt ggtgcaataa ctcatgtttt tagagataat ccgaaaaaag
    37081 gatatggtat ttttatagat gaaatgataa aattgtaggt gaggcattaa aaaattttat
    37141 tattttatca attatctagg aggaatataa ttttggagtg tcgaatatgc tttagagtag
    37201 ataattagga agcaattgtg taaaaagttt agttttctgt aataagaaga tgttttttaa
    37261 tggggggatt tttagtggaa aaaatcaaaa tagttttagc agatgacaat aaggattttt
    37321 gtcaggtatt aaaagagtat ttgtctaatg aagatgatat cgatatatta ggcatagcta
    37381 aggatggaat tgaagcatta gacttagtaa aaaagacaca accggactta ttaatactag
    37441 atgtaataat gccacatcta gatggattag gtgtaattga aaaattgaat actatggata
    37501 tacctaaaat gccaaaaata atagtactat cagcagtagg tcaagataag ataactcaaa
    37561 gcgcaataaa tctaggagca gattactaca tagtaaagcc atttgatttt gttgtgttta
    37621 taaacagaat tagagagcta gtttctaata gagttacaca agttgagcca aaacctagac
    37681 cagttcaaga gactcaaatg actagaagtg attttgttaa gaatgtagga aatatagaga
    37741 cagaaatcac aaatataata catgaaatag gagtaccagc tcatataaaa ggatatttat
    37801 atttaagaga agcaataaaa atggttattg ataatgttga gcttttaggt gcagtaacaa
    37861 aagagttata tccaagtata gctaaaaaat tcaatacaac accaagtaga gttgaaagag
    37921 caataagaca tgcaatagag gttgcatgga gtagaggaaa agttgacaca ataaatcaat
    37981 tatttggata tacggtacac aatactaaag gaaaaccaac taattcagaa tttatagcaa
    38041 tgattgctga taaattaaga ttagaacata gtatggttaa ataaacaaga cataaaaagt
    38101 aaggcttttt aattaaggca ttggctataa atgcgtatta caagcagcga aacggtataa
    38161 ccactagggt tataccgttt cgctatttta ataaatataa aaattttctt tattatttgc
    38221 ttactatatc aatataataa ttttattata ctatggatat agtatgtgtc tttacaagtt
    38281 gtaaactgac agtggtttat tttttaatat aaatattgac tttgatgcag gtaaactttg
    38341 tatttttaag cgtattatgg aatatgttaa ataaaaaaat gatgaaatat agtattgtaa
    38401 atgccaaaga tgcaaaacaa acttaaaaca tttattttat tgttaagtaa tgctataata
    38461 taatgtgatt ttaataatga tagtggaggt ttaaatatga gagtcgaggc ccctataaaa
    38521 gtagatcgaa aaaccaaaaa acttgctaaa agagttgaaa gtggggaaat agcagttata
    38581 aatcatatag acatagatga agttgctgca aactctttag tagaagctaa aataaaactt
    38641 gtcataaatg cggctccttc tataagtggt aggtatccca ataaaggtcc agggatatta
    38701 actgaaaata atatactaat aattgataat gttggagaag agttatttga agaattaaaa
    38761 gaaggagaaa ctatagaagt tgtagatgga aagatatata gaaaaggaaa atttttaggt
    38821 gcaggagaag ttttagacaa gtatgaggtt tcacaccaaa taaaggctgc ctatgagaat
    38881 ttagctgtag aattggatag atttatagat aatactatag attatgctaa aaaagaaaaa
    38941 ggatttatac ttggagaagt agaaattcca aaagtgaaaa ctaattatgc taataaacat
    39001 gtattgatag ttgtaagagg tcaggactac aaagaagatt taagtactat gctttcttat
    39061 atagaagagg taaagccagt attggttggt gttgatggag gagcagacgc tttaattgag
    39121 tttggatata ctccagatgt gattgtaggt gatatggata gtgtaagtga tgaagcttta
    39181 aaaaaggcta gtgaaatagt agtacatgct tatacagatg gaagagcacc aggtcttaag
    39241 agggttgagg aattaggctt agatgcagtt gtatttcctg cgccaggaac tagtgaagat
    39301 atagctatgc ttatagccta tgagtataag gctgagttaa tagtagcagt tggtacacat
    39361 tcaaatatga ttgattttct tgaaaaagga agaaaaggta tggcaagtac ttttttagtt
    39421 agactaaaaa taggttcaaa gcttatagat gctaaaggcg ttaatttgtt atacagaagt
    39481 aaattaaaaa taaagtacat atgggcatta atagcaacag cattatttcc tgtgttggta
    39541 gttgcatcat tgtcaccagg agttcaacag ttcatacaac taatgcaatt aaagtttaga
    39601 gtattattac agatgtaaat tttaggagga taaatatgca tattaatatg aaatattata
    39661 tagtcactat aggggctata tttatagctt tgggtatagg catgttagta ggatttaatt
    39721 taaataataa tcaacaatta agtgaacaac aagcaaatat aataaatgat ttggatgata
    39781 agtttaatat cttaaaagaa aaaaatgata aacttgacag tgacttagca agtgtaaata
    39841 gagattatga agaggcagtt aattttataa ataaaaatgt agataagatt ttagctggtt
    39901 cgctgaatgg taagagtata ggaataatat ctgctaatga aaatgacgat tatacaaaaa
    39961 atatagaaga cataataaat aaatctaatg gaagcattgc atttaatata atattaaaag
    40021 aaaacataac aaatccagaa aagttaaagg aaatgtcaac taaactaggt acagatgtaa
    40081 aaaatgcaaa tgatgcagtt aattatataa ttgacactct taaaaaggaa gatgcaagtg
    40141 acattttaac atatcttcaa gaactagatg taataaagtt taattttatt ggagatacat
    40201 atctaaaata tgattccgtt gtaatagctg gtggaaatga tgcaaaagac agtacaaaac
    40261 agtttgaaaa aatagaaaaa tttgtagttt caaaacttaa atcagagaat aaatatttag
    40321 tagaagttca aaatacagga gttaaaactt cttatgtaga actatattct aaaaacaaag
    40381 ttgcaactat agacaatatt gatgaaggta taggaagtat atctctagcg attcttctac
    40441 aacaaggtaa tatagttggt aattttggta gattggatac tgcaacttca ttgttgccat
    40501 ctattaaata gaaataattt taaggagaga aaaaatggat tcttatataa gtataataat
    40561 accagcttat aatgaagaaa gtagaataaa atatacatta gaaagcatat tggacattaa
    40621 gcaaataaat gaaataatag ttgtggatga tggttcaatt gacaatactg ctaaggttgt
    40681 atctgagcta gaaaatgaaa agattaaatt ttttaagtta gataaaaata gaggtaaagg
    40741 atatgcttta aattatggta tcaagttagc aatgaaaaat gcagatatta taggttttct
    40801 ggatggagat ttaggaagtt ctgctaaaga agttgaaaaa ttaatagtac ctatattaaa
    40861 tggtgaggcg gatgttacaa tagccaagtt tcctcctgca aagagaaaag gaggtttggg
    40921 atttgtaaaa ggtttagcta aaaattctgt gtttgagatg actggtgttg agttagatgc
    40981 aactttatca ggtcaaagaa tatttaaaag agaagtttta gaaaagtttg atgaaatacc
    41041 ttttggatat ggagtagaag ttggaatgac cattgatata ttaaagtatg gatttaaaat
    41101 taaagaagta ttagtaaata tgactcataa tgaaacagga agaaatttaa aaggttttat
    41161 tcatagaggg aaacagtatt atcacataaa aaaggtttta ggacaaaaaa agaaagaatg
    41221 gaggtaatat cttagtgaaa gattatatac tttataccat tttattatta actggattat
    41281 ttggaaccta tgctgtaatt ccactattta aaaatttatt gataaatgga aatgtactta
    41341 gaccaaacta taaaaaagat atgataccag taagtatggg aattgtattt ttgcctatga
    41401 ttgtaatcaa tggaataata cttgctttct ttactacaga atttaagaat ttagcgtata
    41461 tatttatgtt tatgtttggt atgatatcca tgttttttgc agggatacta gatgatgtca
    41521 ttggaaatag agatgtaagt ggtttaaagg ggcattttaa aagtttattt aaaggaagtc
    41581 ttacaacagg aggttttaaa gctttatttg gtggatttgt agggcttata gtttctgttg
    41641 ctatatcaaa agacataatt gatataatag taaatacact aataatagct ctatcaacta
    41701 atttaatgaa tcttttggat ttaagaccag gaagggcaat aaaagcatat ttattcataa
    41761 tggtaattgt atttttaaca ttgacaggat ttgttcaagt tcttccatta cttatagtac
    41821 caaatgtact tgcatacttt aattatgatt taaaagcaag ggctatgatg ggagatactg
    41881 gttcaaacgt ccttggaata tctattggaa tgctcatttc ttttgggtat ccatttaaca
    41941 ttagattagg atggttaata tttgtagtta ttatgcatat attcactgag aaatactcat
    42001 taactaagat aatagaaaaa aataaactat taaattttat agataaattg ggaaggtagt
    42061 attatgataa gcaaaagagt ggggattgtt gaatcaatag taagtcaaac tgaaactcta
    42121 gatgatataa gagtaaatat aaatggagaa atacaaaagg catataatta tccaaaaata
    42181 tctggaacta taaatatagg tgacgaagtg gttttaaata caacagcagt agaactgagc
    42241 ttaggtacag gtggatacca ttttgtaata actaatttaa ataatataga atctacttta
    42301 actgaaggtg gacatataat gaaacttaga tatacgcctc ttcaaataaa agtggattct
    42361 gttgaggaac aagaaagtat ttatcatgat aaatttgcga attttaaagg attagaaggt
    42421 ctttctgttg tagtagggac tcttcatagt atgttaactc catttgcagc ttcatttaaa
    42481 agaaataatc caaataaaaa attagtgtat ataatgactg atggagcatc tcttccaatt
    42541 tatttaagta aaaatgtgga tactttaaaa gaaaaaaaat taatagatag tacaataact
    42601 ataggaaatg cgtttggtgg agattatgaa tgtataaata tatatactgc attaattaca
    42661 gcaaaagaaa tactaaaagc ggatgcagta tttgtcagta tgggacctgg aattgctggg
    42721 acaggaacaa aatatggatt tacagggatt gaacaaggct ctattcttga tgctgtaaaa
    42781 aaacttgaag gaagagcaat tgcaattcca agaattagtt ttgctgacaa acgagaaaga
    42841 catcaaggta tttcacatca tagtatgact gtatttaaag aaattgtaaa tgtaaatgta
    42901 gacataccaa taactatata tgatgatgaa aaattgaact ttataaaaga gcaaatcaat
    42961 ttaaatggtt tagacaaaaa gcataatata atttatatag ataataataa aacgaaagag
    43021 gatttagact attttaatct aaaagtaaag agtatgggaa gaaattatga acaagatgag
    43081 gcatttttca aagctgcaag cacagcagca tattacttaa tggaggttta agatggtatt
    43141 agaagaaaaa actattagta gtgatagggt ttatacaggt aaagtaatta ctttaaaggt
    43201 tgatactgtt gaaattccag ggcaaggata tcaaaaaagg gagttagtag aagttggtgg
    43261 agcagtagga atagttgcaa tcacagatga taataaagtt gtgttagtta agcaatttag
    43321 aaaacctata gaaaagccaa tctttgaaat tccagctggt aaactagaaa aaaatgaaag
    43381 tccaaaagaa tgtgctgaaa gagaattaaa agaagaaact gggtatagtg caaaaaatat
    43441 taagctaata cataaatttt tcacttcagc aggtttttct aatgagataa tgtttgtata
    43501 tttagcaaca ggtcttactc caggagagaa taatttagat gcagatgagt ttttagatgt
    43561 ttatgaaatt gagcttgaag aagcatataa catggtatta aaaaatgacg ttgaagatgc
    43621 aaaaacatct attggattat tattagtaaa agatatgttt aaaaattaat atttataaaa
    43681 tgaataaccc tttgtcctaa agcatattat tttataaagg acaaggggga attaaattga
    43741 gaagaacata tagaaaaaat gattttagag aattaaatag acaaataatt attataggat
    43801 tgttgtttat gatgtctatt gttgttgggt cttacataaa taaaatattg ccaggttcta
    43861 gtaacaatat attaaacaat ataaatcctg ctgtagagta ttataatcta aatataagca
    43921 taaaagatac agtgatacaa aatttaaaat cagatgcaat ctttatgggc tcaatagctc
    43981 tattaagtct atttgtagta acaattccag cagtgttggt agcttttgta ttaaaaggga
    44041 tgtcaattgg ttatacaata aatagttgta tattggcatt aaaatttaaa agtataaaaa
    44101 tgattttaat aatattattt aaaaatttga ttattattcc atgtgcaatc atattagcat
    44161 taattagttt aagttatttt aaagaaatgg tttatgaatt taaaaagaaa agtagaaaaa
    44221 atatgcaatt tttaattaag aggtatatac taaatattat aattataata gcactatcat
    44281 tggggttgca attaatatta aatactgcaa gtattggtat tattaagttc ctagctaaat
    44341 aaaggagttt ataatggata ttatagaggg atatatagat tacataaaag ataaaaaaaa
    44401 attatcagag aatacagtgg catcatactt tatggatata aaaaaatata tggaatatat
    44461 aaatcaaaaa agcattaaac tagtagatat agtagaaaat gatattataa gttacttaat
    44521 aaagttggaa aaagataatg tatcaatagc tacaatagcg aggatgatat cctctataaa
    44581 atcttttcat gattatttat ttttaaatca tatatgtaca aataatcctg caaaggatat
    44641 aaaaaaacct aaaataaaaa aagaaaatat aaatatactt acagaagaag aaattgaaag
    44701 actattaaat tttccaaagt taacaacacc taagttgatt agggacaagg ctatttttga
    44761 agtattatat ggtactggta taaaagtatc tgaattagta gagatgaata tagaggatat
    44821 tgacctagat attgattata tatattgtaa ttcatgttgt aaaaatcaaa gagtgatacc
    44881 actttgtgat attacaaaac tttacttaga aaagtatcta aaagaagcaa gacctaaaat
    44941 ggctgcagaa ggtgaaaaat cattattcgt aagttcatta ggtcaaaggt ttacacgaca
    45001 aggtctttgg aaagtcataa aaaaatattc taatctagcc aatatagata aaaatataaa
    45061 tcctacaatg cttagacatt catttgctat tcatttgtta aatgaaggtg ctaacattgc
    45121 tgttgtaagt aaaattttag gaaatgttaa tttatctagt ttgcaagtat atttaaatca
    45181 tatagataaa aacgtgagaa gagaaataaa ggagaaacat cctagaaatg atgttgatgt
    45241 agaattacaa aaagcagaag ctaaatagac tatatagcaa attttataat ttagaaggag
    45301 catatttata tgagcagagt aatttggatt gtaattgata gtgttgggat aggagcatta
    45361 cctgatgctg aaaaatttgg tgatagtaag gatgtaagta cccttggaaa tatatttaag
    45421 gaatatccag atattcagat tcctaatatg agaaatttag gtataggaaa catagaaggt
    45481 atagattttt ttgaaagtat aaaagaacca ataggttgtt ttggaaagtg taaggaaatg
    45541 tctcagggaa aagatactac tacaggtcat tgggaaatga ctggtataat agttgacaaa
    45601 ccatttaaga catttgaaca tggattctct aaggagataa tagaagagtt tgagaaaaaa
    45661 actggaagaa aagtagtagg aaataaacca gcttcaggaa ctgtaataat agatgagtat
    45721 ggagagcatc aaataaaaac tggagatgta atagtgtata catcagctga tagtgtattt
    45781 cagattgctg ctaatgaaga agtaattccc ctagaagaac tctataatat gtgcaaaatc
    45841 gctagggaaa taatgatggg ggataatgca gtagctagag taattgctag accattcata
    45901 ggtaagaaaa aaggtgagtt tgtgaggact tcaaatagaa gagattattc actagaccca
    45961 tttgaaccaa cagttcttga taatataaaa gaatcaggac ttgatgtttt agcagttgga
    46021 aaaatagaag atatttttaa tggaaaagga attacagatg ctatccacac taaaagcaat
    46081 atggatggag tggatgaaac tttaaattat atgaaacaag ataataaagg tctaatatat
    46141 tcaaatctcg ttgattttga ttctaaatat ggtcatagga gagacccaga aggatataag
    46201 aaagctcttg aagagtttga tagtagactt cctgaaataa tggctaatat gagagaagat
    46261 gatattttaa taatcaatgc agaccatgga aatgacccaa catataaagg tacagaccat
    46321 acaagagaat atatacctgt tatgatttat ggcaataaga ttaaaaaagg ttttaattta
    46381 ggagtaaaag atacttttgc tgatattgga gcaactgttg cagatatact aaatgtaaag
    46441 ttgcctaaac atgggtcaag ctttaaagaa gatttatttt aaactataaa atgataaaaa
    46501 cttagcttaa taggatggag agattggaat gtttgaaaag atagcacaaa gtagtaaatt
    46561 tataaattct aaaagtaata taaaacctaa gattggtttg atattaggtt ctggactagg
    46621 tgatttagca aatgatatag aagaccctgt cacaattaaa tatagtgaaa ttccaaactt
    46681 ccctgtatca acagtagcag gacatgctgg acaacttgta attggaaaac ttgaaggaaa
    46741 agaagttatt gctatgcaag gtagatttca ttactatgaa ggatattctc agaaagaagc
    46801 tacttttcca gtaagggtta tgaaagaatt aggagtcgag attcttatag taactaacgc
    46861 tgctggaggc gtaaataaag aatttaaagc aggagatttg atgcttataa gagaccatat
    46921 aaactttagt ggaagtaatc cattagtagg aaaaaatgat gacagatttg gtgctagatt
    46981 tccagatatg tcagatgcat attcttctaa atatgtagat gtagttaaaa actgcgctaa
    47041 agaatgcaat atagatgtca aagaaggcgt ttatatgttt tttagtggtc caaactatga
    47101 aacaccagca gaagtgagaa tggcacaaat tttgggagct gatgctgtag gtatgtctac
    47161 tgttccagaa gtcatagtag cttctcactc taatatagga gttattggta tatcttgtat
    47221 aacaaatatg gctgctggca tcttaaatca accactaagt catgaggaag taatagaaac
    47281 tactcaaaaa gttaaatcag aatttatgaa tttagttaaa acaacggtta aaaatttata
    47341 agttaaagct tattatagat tttttgagga agtttataat aaaatagtta atgtttaatt
    47401 tgaaaagaat taataaaaag ctgtcttgat atagaaagtt atttctaata aaggacagtt
    47461 tttttataat actacaacat ttgaaagtgt tttaaagttt aatatttatt taaattatta
    47521 taggttagaa tggagatttc aattatgaga atgtatgata ttataaaaaa aaagagagat
    47581 aacctagagc ttagtaaaaa agagataaac tactttatag aaaactattc aaagggagat
    47641 atacctgact atcaagcttc tgcactatta atgtcgattt atttaaataa gatgaataaa
    47701 caggaaactg tacatcttac agaagcaatg atgaactctg gagacatgat aaacctatct
    47761 gagatagatg gaataaaggt agataagcat agtactggtg gtgttggaga taagactacc
    47821 atagctctta tacctttggt tgcttcatgt ggagcaccag ttgcaaagat gtcaggtaga
    47881 ggtcttggtc atactggtgg tactattgat aaattggagt ctataccagg tttttcgaca
    47941 gaaatggaga taagtaaatt tattgattct gtaaataagt ctaaaatagc agtttgtggt
    48001 caaagtgcaa aggtagcaat tgcagataag aaaatatatg ctcttagaga tgttacagca
    48061 actgttgata atatatcatt gatatcatca agtgtaatgt ctaaaaagtt agcttcagga
    48121 gctgatgcaa ttgtgctaga tgtaaaaact ggtgatggag catttatgaa gacattagaa
    48181 gagtcttttg agttagctaa atctatggtt gatataggta ctggtatgaa tagagataca
    48241 atagggattg taacagatat ggatgaacct ttaggttttg cagtgggaaa ctctttagaa
    48301 gttatagagg caattgagac attaaaagga aatggaccta aagaccttgt tgagctatgc
    48361 gaagtattag gagcatatat gttggtttta tcaaaggtag cacatgattt tgaagatggt
    48421 gttgaaaaaa taagagaatc aataaaatct ggtactgcta tacaaaaact caaagagttt
    48481 atagagaatc aaggtggtaa taaagatgta gtagatgatt attctttatt caaaaaatca
    48541 aagtataaat atccagttaa atcaactaaa tcaggttata taagcaaaat taaagctgaa
    48601 gatgttggtg tatcggctat gattcttgga gcaggtagag aaactaaaga tgatatttta
    48661 gatttatcag cagggataat tttagaaaag aaagtaggag attatgtaaa tgaaggtgaa
    48721 gttttagctt acatgtatta taatgatgaa caaaagcttt cattggcaaa gggaagattt
    48781 attgattcct actctattgt agattcaaaa atagaaaaaa ataaattaat atatggtatt
    48841 gtaactaaag aagagattaa aaagttttag aaaattttag aaaagtgatt ataaaaggcc
    48901 taacatgtca aaaataatgt taggtttttt attttttgat aaactataaa ttataccaaa
    48961 aatatatatt ttaaaacatt ttttacaata taaataagtt tattctacaa gatgattgaa
    49021 aattaaagta tctagtttta taatagaaaa tggataaata tacataagga gtagattata
    49081 ttatgaactt taaagaaaat agattgaaaa tagcagtatt aataattgtt attttgatta
    49141 tcttagcagg tatatttgtg tttatacaaa taggtcctta tgataaaaat aacaaaaaag
    49201 atgtaattat cgacgttcca agtggagcat ctgttggaaa aatatctgac atattatatg
    49261 aaaataaatt aataaagaat gaactattat ttaaactttt ggtaaaggtt agcaataaag
    49321 ctccgtctat aaaatcagga acatacttac ttaatcaatc gtattcaaac aatgatataa
    49381 taagtctttt agtttcaggt aaaatatatc aggatggtat aaaagtgact attccagagg
    49441 gagctacatc taaagaaatt atagcaatgt tagtaagtaa aaatttagga gataaagcta
    49501 cttttgaaaa tttaataaaa aaacctcaag aattttatga taaattttca tatttgaagg
    49561 aagatggaat aacctcttta gaagggttct tgtatccaga aacttattat tttaattcaa
    49621 agaaacaatc agaagaagat attttaagcg aaatgttaaa agtatttgac agtaaataca
    49681 cggacaagtt taaaaagaaa caaaaagaat taaatatgac tcttcaagaa gtaatggaaa
    49741 tggcatcaat aattgagaaa gaagctgttc ttgacaaaga cagacctata atagcaagtg
    49801 tgttttataa tagacttaag gtaggtatgc ctcttcaatc agatgctaca atacaatata
    49861 tatttgaaga gagaaagaaa attgtaacat atgatgattt aaaaattgat tcaccatata
    49921 atagttataa aaataaggga ttacctccta caccaatatc aaatcctggt ataaaatcta
    49981 ttgaagcagc attatatcca gagaaaacag actatttata ttttgtagct aagattgatg
    50041 gtggaaataa ttatagtaca aactatcaag accatttaaa atacgttaaa gaatataaag
    50101 aagcaaggga taaacaatca aaagatacaa aagcaacaaa taaagaaaat acaaaaaaat
    50161 aaaccatgat tataaaaagt ctaacagggt aagaataatg ttgggctttt ttattgaaaa
    50221 ttgttattct tagatttata ataaagaaag tgtaaatata tataacaata tgaatttaaa
    50281 aaataataaa ttaatataaa acttggatat ttattatttt agggagtgtt tttatgagta
    50341 atatagttaa tgatttggtt gaagattata taagagtgac attaaaagaa aaagaaggat
    50401 ttttaaaaga tttagaaatt tatgcagagg aaaatagtgt tcctataata cataaagaag
    50461 tttcagattt attaaaagtc ttgttaaagg ttcaaaaacc aaagagaatt ttagaagtag
    50521 gatgtgcaat tggttattct tctatttttt ttgcaactat tataggaaaa gatgcagata
    50581 taataactgt tgagagaaat gaaaaaatga tagaaaaagc aaaagaaaac ataaaattag
    50641 ctggatttga caataacata actatactag aaggagatgc agaagaaaaa cttagtcaag
    50701 tccaaggtga atttgacctt atatttatag atgcagccaa aggtcaatat aagctatttt
    50761 ttgatttagt tatagataaa ttaaaagatg ggggactttt agtatctgac aatattttgt
    50821 ataaaggtat ggttgctcat gatgattttg ttgtaagaag aaaaaagact atagttaaaa
    50881 gaatgagaaa gtatttagat tatatatgta attgtgacta tttaagcaca tcattggtac
    50941 caataggtga tggtgtagca ctaagttata aagaaagtaa aagaggtgat gtagatggaa
    51001 ttaaataaag tagaactttt agctccagca ggtgatttgg agagattgaa aatagctata
    51061 acatatggag cagatgccgt ttatataggt ggagaaattt ttggaatgag gtctgcagcg
    51121 aagaatttta gtaaggaaga tatggcagag ggagtagctt ttgcacatga aagaggcaag
    51181 aaagtattcg taacagtaaa tataatacct cataatgaag attttctaca attagaagac
    51241 tatttgttgg aactagaaga gataggaata gatgcagtta taatagctga cccaggagtg
    51301 cttagtgtca ttaaaaaagt aattccgaat atggaaatac atttaagtac acaagcaaat
    51361 acaaccaatt atctaagtgc aaacttctgg tacgagcatg gaataaaaag agttgtagtg
    51421 gcaagagaat tatcttttga tgaaatatat gagataagag caaaaacacc tttagatatg
    51481 gatatagaag cgtttatgca tggtgctatg tgtatttctt attctggcag atgtttaata
    51541 agcaactata tgactggaag agatgcaaac aaaggttctt gtgctcaatc ttgtagatgg
    51601 caatatcatt tggtggaaga aaaaagacct ggtgagtatt ttccaatata cgaagatgaa
    51661 aggggtacat tcttctttaa ctcaaaagat ttatgtatga tagagtatat accagagtta
    51721 atcaaatctg gtataacaag tttaaaaata gaaggtagaa tgaagactgc atactatgta
    51781 gctactgttg taagagcata cagaatggca atagatgaat tttacagaga cccagaaaac
    51841 tggaagttta atccaatgtg gatggaagaa ctaaaaaaag gtagtcatag acattttaca
    51901 tcaggttttt acttgaataa accaacaaca gaagaccaaa attatcaatc agcatcatat
    51961 gttagaaact atgattttat aggtatagtt agagaaacag aagatgaaga tggtcttatt
    52021 gttgttgagc aaagaaataa aatgtgtgtt ggtgatgaaa tagaagttat gggaccatat
    52081 aaagaaacta tgtttactaa aattgaagaa atgtataatg aagaaggaga agctatagaa
    52141 tcagctcctc atcctagaca aatagtgaag ttaaagctat cagtaaaagt tggtaaagat
    52201 tatatgctta gaaaagttat agaagaaaag gttgaagaat aataaaaaat tgataaaaat
    52261 agtattagcc ccttagaaat tgtcaataat gaaattatct aaggggtgat ttcatgtcaa
    52321 aaaagaagac tccatttttg aaaaaagtgg gaaagagaag ctggtgtata tttactataa
    52381 ttttaataat ttatagtgtt ttaatttata ggctagttga tatacaagta ttaaaaggtg
    52441 ataaatacaa acaaagtgtt gaatcacaaa gcgttgagaa agtcgagtta aatagtggaa
    52501 gaggaataat ctatgataga aacaacaaga agcttacaga tacaagtaaa tctcaggtat
    52561 taattgttga aaaagaaaaa ttaaataata actataaaat tttggagctt attaagaaag
    52621 ctactaagat gaatgattta gatatatata aagctgtaca agagcaattg acacgcccta
    52681 taatacagat tcagactaaa aatatcgata tcgataagag tatgaaaaaa gaacttgaga
    52741 aaaatggaat aatggtagaa gaaaaaacta tgaggtacgc aaaagatggt ttattatcac
    52801 atacaatagg atatataaaa gaagatgata aatcaggtca atcaggaatt gaaaagagta
    52861 tggatagtgt acttagaaat tcaaatgaaa agtatataag tgcttttaaa gctggagatg
    52921 caggaaatga aaaatctcta aacatactaa agggaagtgt aaaaactgtt gataataagg
    52981 ataaagatag acatctaaaa actactattg attataacat tcaaaaaaaa ttagaacaaa
    53041 tactaaataa agaagaaaat cctacagcag caataatctc ggaagcatct acaggtgaaa
    53101 ttcttgcaat gtgctctaga cctaattttg accaaaatga catatcaaaa agtttaaaag
    53161 gaaaaaatgg agaatttgaa aatagagtta taaaagcgac atatccacca gggtctgtat
    53221 ttaagatggt agttttattt tctgcacttg aaaatggtgt tatagatgag aactatactt
    53281 acaactgtac aggtaagact aaagttggga atactaatga aatactgcga tgtaataaaa
    53341 gagatggtca tggtttccaa aacttaagac aagctttttc taattcatgc aatcctgcat
    53401 ttttagatat agctatgaaa cttggaaaag aaaagatact caaatctgct gaaaaattac
    53461 atttatttga aaaggttgat attggtcttg atgaagaaaa aattagagaa gctccaaaaa
    53521 acatatcaat aagaaattta gctataggtc aagaaaatat agaatttaca ccacttcaaa
    53581 taaatcaaat gactcaaata atagctaata atggaacatt caaaccacta tacttatata
    53641 aaagtcttgt ggacaataat atgaatacaa taaaaactta taagtcttca aaaaaagaag
    53701 aacttatttc tccttatgtg tgtacacaag ttaaagaata tatgaagtct gtatctagga
    53761 ctggtacagc taaagaccta aaagatattg aaggtggttg tggagttaaa actggtacag
    53821 ctcaaagtag tttaaataaa aaagctatag accacggatg gataacagga ttttatcctg
    53881 aagaaagacc taagtatgta ataactgtgt tagtagaagg aactcaaaaa ggaaataaat
    53941 ctgcaacacc tatatttaag gaaatatgtg aaagtataaa ataaattatg tactataaaa
    54001 tttaaggata tatcgtaact ttgattttag atagaaaatt ttgtctaatg atgtacgata
    54061 tatcctttta aaatatagta ttaactttct tgaacaagct ctttttctag ttttttaaga
    54121 gctttttttt cgattctaga tacatatgac cttgatatat cgagtttttg tgcaatttct
    54181 ctttgtgtct tatagccata aggagttaac ccatatctta actggacaat ttctctttct
    54241 ctaggagtaa gaattttgtt tagttgttcg taaagttttc caacttgaac ttttagttca
    54301 acttcatcaa gaacatagtt agcctctgta ccaagtatat ctaaaagact tatttcatta
    54361 cacactactc tttatatgtt attggtatta ctggtcttca tgtaatttca aatggaccat
    54421 taattcaaaa gaatctagtt tttgttcttt agacttataa taaactgctt tatcaattac
    54481 agattttagg agtttatttt ttccaaggga atctgaatca tggtaaagtg ataacacagt
    54541 tttaatatct tctattattt tagaattgtc ttttttaaca gtactcaatc tattttttac
    54601 tgtcttaatt gaatctttaa tttcttcagt tcttgaactt atattgttgg acctttcaat
    54661 aaatgtatct tcatcatata ttcctcgttc tagtaaatca tataacttat ttttttgctt
    54721 gcctaattct tttaattcag tttctaagcc ctttaagact cgtttttgaa attctatatt
    54781 actatcttta ttatttttat ctaagtctat atcagatgct tttaattgat atttttttac
    54841 agtgtcttcc aaagatttta aaatggcagc ttcaataaat tcaaatcgag aacttttatt
    54901 gcaaccagga tgataacaaa ttatatagtc gtggtctgca tatggtctat atactaatgg
    54961 tctaccacaa tttttgcaaa tcactattcc tgcaagtgga ttttttattt gattaccata
    55021 gctgacatga ccattttttt tgagtatatt ttgagctttt ttccatgtta tttcacttat
    55081 taaaggttca tgctttcctt ttgcctcaat ccattcatct ttaggtctta gtttaactgt
    55141 ttttatttta tttggatttt tagatttttt gtagtccttt ttttgccact gaatgtagcc
    55201 acaatatgcc ttatttttta ttatatttgt aattgcagaa ttgtaccaat tagcacctgt
    55261 agcagtttta atgcctaagt tatttaggta ttttgatatt ttactacaac ccatatcttc
    55321 attaatatat aagtcaaaga tagtcctaac tacatcagca tctttatttg gtacaagtat
    55381 tctttctttt ctaccagttg ttacagcatc atatccaaat ggagcagagg ttcctatgaa
    55441 attcccttct tcaactgatt ttattctacc tctttgcatc cttcttgata taagttttaa
    55501 ttcttttctt gccataaatg cttcaaattc tgaatactcc tcatcaaatt catctgttag
    55561 gtcgtatgtt tttctaggtg tgatgatttt ggtcttactt tctttgaatg tttctaatat
    55621 gataccttgg tctttcatgt ctccacgacc aagtctgtct aagtccatta ctaagactgc
    55681 atcatattta ttttcttcaa cttcttttag aagttcaagc attttgggtc tatgtattat
    55741 actttcacca gaaactaatt cttcttttat ctcaattaca tctaagtttt gttcttttgc
    55801 tagttttagt agggttgatt tatgtctact taaagtttca aattcgcctt gtttttctgc
    55861 ctcttcatca gcacgggatt ttcttaagta tatggcaaca ctcataataa gtaatcacac
    55921 tccttatgca ctattatata gtaaatcaat agagtttaaa atatagaaaa taagcatgtc
    55981 aaaagttaat ttaacttttg acatacttat tttctataat attaatgcct tataatcctt
    56041 taatatcatt tagattagtt tttgcatatt cattatccgg gttaagttca agcgccttat
    56101 tgtaagattc tctagcttta ttaaattctg atttactcat aaaaataaca cctcttaaat
    56161 tgtaagcatc actagcgtct attttataag cttcattatt tttatctaga tattctaagt
    56221 atttatcaat tgactttaaa gcctcatcat atcgttgtaa ctctatataa atatatgatt
    56281 gtgtataata tgcaagtgga tttttatcat caatttctat agcttttttg atatcaatag
    56341 cagctttatt ataatcctta tcttcatctt tttctgtttc tgacctagcg attttgacat
    56401 aattagagct aagagctctt ttaaagtctt tatgccataa taatttatat tcattatctt
    56461 cgattataaa atatctatca aaatttgcag tatcttcttt attttcagtg atatacttta
    56521 tagtatcagt ttcttttatt ttaacaagat ttgtgtactc tttattagaa tatttgtatt
    56581 tctctacttt attttcttca ccaagtttat aatcttttag ggtttgaagt ttaaataaag
    56641 tatcttgata ttcttcaaat ttttctagac tgacactttc cttactgtct ttacttaata
    56701 aattatatgc tacttcgtag tctttgattt ctatactatc aaggtacttt ttagctactt
    56761 ctgtagcact ttcttttgga gcacatccaa ccattgatat cataattaaa aatgatacta
    56821 atattgctgt tattttttta ctgattatca taatataatc ccccttatat tgtctctcat
    56881 taattttatt ttatcaccat attctaccaa agtcattaat ttaagagtga tatttttcat
    56941 taatattata ttaagtaata ataacctttt aaatttatgg taaaattttc ctgaaaagta
    57001 ttatataatt taggtgaaaa tatttaagag aaggagatat tatgaaaatt aaaaaattat
    57061 taacaatagg gttatcttta tctatattta ttgctagttg ccctatatct gtaaatgctc
    57121 ttgataaaat tgaatcaatt aaaggtgcag ataaatacga aactgctggt ataattgcag
    57181 acaaacaaaa ctatactaca gctatattaa ttaatgcaga cagtacaatg gctgatggat
    57241 taagtgcaag tggacttgca ggagctataa acgctccaat tcttttgact aagaaaaata
    57301 acataccaaa tgctacactt aaaagattag aaaaggcaaa aaaagtatat ataattggag
    57361 gagaaaactc tattgataaa tatactgaaa ctgttctaaa aggcaaagga atagagatta
    57421 aaagacttca aggtagtgat agaattaaga caagctataa tgtcgcaaaa gaaataaact
    57481 caattaacaa agtaaataaa gtcatattga ctaatgcatt taaaggagag cctgatgcaa
    57541 tgagtgctgc acctgtagca gttagagata aagcagctat agtattaact gatggaaaaa
    57601 gtgttccatt taatacaact ggtgtagaaa gttatgtaat aggtggtact tcatcaatga
    57661 atgacaaaat agttaaggat actaattcaa ctagattagg tgggacagat agatatgata
    57721 ctaacaaaaa gataataaat aaattttata gtggagtaaa agaattttat atagcaagtg
    57781 gtactgattt agtgtatgct cttgttggtt ctactgttgc taaaaataat gctattgtgt
    57841 tagttgataa tgatagtaat aaaagtgtat tgaaaagtac aactaaatta actgctatag
    57901 gaaatttgag tgatagtata ttacagcagt gtttaaatgt aacaaaaaat ataggcgatt
    57961 ctaatactgg aagagaatat acagtagaag atgctgctaa tgcagtgaaa aaactattag
    58021 gtgtgaagaa attttattac gaacctaatt attcagaaga tgaagattta atatttctac
    58081 tagataaaaa ttttgatttt tcaggaaaag agtactatgt atttgcttac attaaacagg
    58141 gtgcagaggg tgatgttaga tactgtgtag ctaaaaatga tatgagcaaa gtttatacat
    58201 atgatgttaa tggtaatatg aaagtatgta atccagatga ttataaaaat aaaggaagta
    58261 taacagagga acaagcaaaa cagatagcat taaaagaatg tgctaagaga cataaagtca
    58321 gtatcaataa cttagtagtt gatatgatag attttagaga tgatatatat agtggtaatg
    58381 tctatgctgt taaaatcaat tcaaaaaata gtaatggtac ttttggttgg ttttttatag
    58441 atatagaaac tgggaaagtt tataattaaa attagaactt ttaaacaagt gtttttaatt
    58501 atataattta ccataatatg ttataatatt tttagcaaga agatttaact tacaatctat
    58561 agagtggagt tcatgtacaa aagattatcc tcccaacgat tcgaagggag gtgagttcat
    58621 ggataacttt ttgtttaatg ttttagctag tttaacagct agtgtggtag tttacttaat
    58681 tagtaaacta ttcaaaaaag caaaaagcca ctctcgcaca aagagtgact tacgagttga
    58741 atttaaattt atatttaaat ccaaaaaata aactctgttt atgatgaact ccactctaac
    58801 gcaaaataga ttgtagttct tcttgctttt attataccac aaaacattat aaataaaact
    58861 gttgtttata aaaaaatgca aagtaaaatt ttttataaac aatgataaaa attttattat
    58921 agagctatta acttattaaa tatctgtaaa tgagcagata tttcataagt taatatttat
    58981 tgtttacata aaatatttgg taaaaataag taagttttat atgttataat agttgtagca
    59041 agaataataa tctaaagtgg caagcatgtc agctggtgtt atatcagttt atatttatga
    59101 taaaataaaa atctcccaaa cgccaataag aatgatttaa aaaaataata ttttcactta
    59161 aaaataatca ctctttatag gagtaaatta ttttcttgat tttattatac tacaaattgg
    59221 tacagatatt taaaaataat atattcataa tattataaat agttttgcag tgagcgatat
    59281 ttttgataaa atagggctta acagttgaaa cataaggcat tgagggtata tgataaatat
    59341 tatcatttgc actactcgtg gttcactgca aatttgagag aattgtatag atgtaagtct
    59401 tggaaatgct caatttattt tggggtttta tattaactaa gtggtatgta aagaagtgtt
    59461 gatatttata ttgtctatcc ccgctagctt gttttatatt aactaagtgg tatgtaaagt
    59521 cgtaaattac gaccgtacct ttcgtaaaat aacaatcgtt ttatattaac taagtggtat
    59581 gtaaagcttt ttgagtatga gtacaagcat aggaaaatta atagttttat attaactaag
    59641 tggtatgtaa agaacaaaaa agatacatct gtaactaatt tttatactgt tttatattaa
    59701 ttaagtggta tgtaaagaca gatataatat caaaataagg ttaggacttt taaaagcata
    59761 gccatatcag taaaaattta attatcattt aaaaaataaa tttttattta aagaatacac
    59821 ataaatattt ccagactcaa ctctcttaaa ctattttcat atcttttagt agataccttt
    59881 gttgtttttt aatctttagc aacttgttct tgagtgaacc tcttattttt tctaagttat
    59941 ttcaagcttt tcaaaaaatt ctctatttat attcatcaca catataatac aattaattca
    60001 gctttaattg ccaatattta gtttttctgt atctgataaa ccaagaatat aatcagtata
    60061 taaaccaaaa attttagcaa atattattaa cccatcgtct cttgttggtc tttcaccaga
    60121 ctctattcta ttcataacac ttgtatttat atttgttttt tcaagcaatt ctttttgaga
    60181 actattcata ttttccctaa tatatttaat cctttgattt acatccatac ataattatct
    60241 cgaaaagttt ctgttttgga aatattgtta ttgaaatata gcaattaatg tgaatatatg
    60301 aaaaagatac actatgattt tataaaaaag aagacataca taaaatttat acttacaaag
    60361 tgttgcaaat gagttaggtt ttaaaaatgc atcaatttat tttaagtaca ggaaagggga
    60421 atattcaatt agagttgata tgttacctat aaactatcta agatacttga ttatgatata
    60481 gaaaattttt ttacaaatta aatttctaag atagaaattt aattaagagg atgatgagga
    60541 tgaataattt acaagtaata taaagaaata ataagagaat tttaaatgca tagcaactag
    60601 cagatatata tgaaaatgat gtaaacaata tataaactaa cttcaataga aataaagaga
    60661 atgtaaatta tgttttatta caattcgagt atttgaaaga atttaagaac taatctatta
    60721 atagtcagtt gatttcaaaa cattctagtc aattatacct ttggatcgaa agatgtgcaa
    60781 atagacactg caaaatatta gatattgata aaacttggga acaatttgac aatttagaga
    60841 aaatatattt caagattaag cgagagaaac taagctgtat agaagatgta ttaatagaaa
    60901 atttaagatt taaggataca aattaataaa gcaataatat ggcattagat gtaaaaatag
    60961 aagttaaaat aataaaagat gttgttatat taaatataac acattggaaa aaagaaacaa
    61021 gtctattaac agttaaaata gctagaagtc aaggtgattt aagttatgta aaatattttg
    61081 ctaatgagag ctaagagctt cttaacaaga gttttggtgt gtctcttgaa acaaggttaa
    61141 caattaataa aagacgaatg gcagaagaag gcgtatgtaa gtttaaaaga gataagttaa
    61201 acaaactaga tactatgtaa gaggataaga aacttataga agaatatgtt acttttgtaa
    61261 aggatttagc tttaaaatat agaatataaa gtgattttaa gtaaaaattg taacaattaa
    61321 ataagtataa gacaagttta tgagttcata ttttataaca aggggtgatg ttatgaaaat
    61381 actacaacaa tttaaaccat acaaatatga taaagaaaaa aatatagaat atgatgaaaa
    61441 aattatagct aatcaaaaca cagaagttta tatagtatat ccacgtatat ctgatgaaga
    61501 aaataggaga agatgggaag agttcaatga agtagctaaa gaagtagcta ttaatatagc
    61561 tatgaagaaa gttgagacag tagaaagtta agagaataga gaagttgcta atacttagca
    61621 ctttctcata gaagaaaatt ggacaactat ttttaaataa ttaggaataa aaaagttaaa
    61681 tcatatttga aaaaaggcga taaaattgtt gagtattgtt attagtaata agaatatatt
    61741 aactatgtat taaaagaaat tataagtttt tagtaaatat agtatttaag gatattaaaa
    61801 ctggtaaaaa atatcattta gactattaaa taaaaaagtg ctggtcaaag tagcaacaca
    61861 ataaataaaa aaacttatag aaattataag ataaaaagat gagatttgaa atggtcgaag
    61921 ttaatataaa aattaaaggt gaagtaagtg aaataattaa ctcaattaga ggtatattta
    61981 atagctttga tgaagaatta atattagata taaaatcaga gtaagaatat aaaggtagat
    62041 acgtagaaag ttataagtaa ttcaagactt aaattaattt ctagtttttt taatgcaaaa
    62101 atttaataaa tttcaaaata taataattct gacatctaaa aagagctatt aaaaatgaat
    62161 aatattgact attaagatat gaatagtgta catatattaa attaagatat caagtaggtt
    62221 aattttatat aatgatgggg ctcaaattga agaggcgata taaaaatgta ttaatatata
    62281 taaatataag aactataata catattaact gtaaaattaa gtttatagag ttatatttaa
    62341 catttaatga actgaaaaat aaattagcaa ataatgaaaa aacaacagta ataaatgaga
    62401 ataacaaagt attttcagga ttagtggatt tttctaattg agctttaatc ctagtttgtt
    62461 caatttcgat atttctaata ttatcaattt atttgtaata attatcaatt tttgcgaaat
    62521 atttttgata atttatagaa ctttatatat tttccttgaa gtatttttcg cccttattgt
    62581 ttggtttcca attttaaaac tcataaactc ccaataaatt catgtataat ataccttaat
    62641 ttataatata tttaagagtt tatttcagta atttttcgaa cgattttgat atatttcatt
    62701 tatagttttc aaaaacttat acaaaaaaga gtgtttcatc tttctaaaca ctctttttat
    62761 aagaatttga ataataattt tttaaaaatt gataatatgg ttatttcttt ttcaagttta
    62821 tagtttcctc atttccattc caagatataa ttagcttgta actagattct ctatttgaat
    62881 aaagacctgg tctttgtatt tttattgctt tttcttgacc tgcttctaaa atttcatttt
    62941 ttacaactac aactgcatct tcaccatcta taaattgata ggaataatta aatttttgtt
    63001 caactacatc tttactattt ttatatttta tttctaattt tgagtgtcct tcagtagtta
    63061 caaatttagc tttccaattt tctgattctc caataaagac atttttatca ttttttatat
    63121 taagtatagc tatcacagag attattaaaa ctataagaat acctataaaa aattttttcc
    63181 tcatatcaat ccctcctttg aataattata acatgagaat agttattcaa tactaatttt
    63241 aaaaatattg tggatttata ttctattaca atagaatgtc tgttataaca aataaaaagt
    63301 aaggattaat atgaattata ggttaaaaaa atctgtaaca actattttat ctttactcat
    63361 aatgacaata ctattaccaa caaatgcaag tgctagtaag gtagaagatt catctatgaa
    63421 agtaatgtat tcagagaaac aagtaacaga catggacaaa ttatacgata tggctaaaaa
    63481 tggaattact gatgttaaaa gttccaatga aaaaggtata atcaaaaatg caagaacagg
    63541 agagtccata tacgttgatt ctatatcaac aactcaatta ttagaagtta aacaatctaa
    63601 aaatttaaca tcaaagatat attctaagac agtttttttg atactaatac aataaagcct
    63661 cttagaaaag caagtatatc agaagatgga tgggataaaa ctggtggtgt aaaagcatct
    63721 ggtacagtta catatacaat atcaaaagga gatggagcat ttcaatatat ttccgttagt
    63781 aaagtttctg gaaactggtc tattgcagac ggccagattc gtgtaacaaa tagaagggtg
    63841 catataaatc aaactggatt tatttctaat gagctaggaa ttaagcagca acaaaagaaa
    63901 gagccaacat caaattcttt ctcatataat gcaccttcta gttggaaacc agtaggtaga
    63961 gattcagttc aatacaattg tgggtttgaa ttaattgcaa cattagtaag aggaggaagt
    64021 tcttgggcat tcaatttcat tgttcaacct taaaatattt taagtgaatt ttattaaaat
    64081 caaagatata catatacttt aaaattagag aatgtaaatt aatttgtgtt tttaaagata
    64141 attcctatgt tatagtaaca attgcttat
//
LOCUS       DAMJWC010000014        63209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMJWC010000014 DAMJWC010000000
VERSION     DAMJWC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 63209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.014"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            32..718
                     /locus_tag="PC503_001090"
     CDS             32..718
                     /locus_tag="PC503_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527102.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
     gene            729..1970
                     /locus_tag="PC503_001091"
     CDS             729..1970
                     /locus_tag="PC503_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527103.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            2041..2724
                     /locus_tag="PC503_001092"
     CDS             2041..2724
                     /locus_tag="PC503_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527104.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            2721..5054
                     /locus_tag="PC503_001093"
     CDS             2721..5054
                     /locus_tag="PC503_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2527105.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSRLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(5162..5724)
                     /locus_tag="PC503_001094"
                     /pseudo
     CDS             complement(5162..5724)
                     /locus_tag="PC503_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5838..7187)
                     /locus_tag="PC503_001095"
     CDS             complement(5838..7187)
                     /locus_tag="PC503_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2527106.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKFFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(7224..8444)
                     /locus_tag="PC503_001096"
     CDS             complement(7224..8444)
                     /locus_tag="PC503_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2527107.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIEIKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            complement(8813..10825)
                     /locus_tag="PC503_001097"
     CDS             complement(8813..10825)
                     /locus_tag="PC503_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527108.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            11296..11946
                     /locus_tag="PC503_001098"
     CDS             11296..11946
                     /locus_tag="PC503_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF2527109.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(12086..13462)
                     /locus_tag="PC503_001099"
     CDS             complement(12086..13462)
                     /locus_tag="PC503_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2527110.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(13478..15391)
                     /locus_tag="PC503_001100"
     CDS             complement(13478..15391)
                     /locus_tag="PC503_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2527111.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            15527..16159
                     /locus_tag="PC503_001101"
     CDS             15527..16159
                     /locus_tag="PC503_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF2527112.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            16298..16837
                     /locus_tag="PC503_001102"
     CDS             16298..16837
                     /locus_tag="PC503_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2527113.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(17013..17183)
                     /locus_tag="PC503_001103"
     CDS             complement(17013..17183)
                     /locus_tag="PC503_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2527114.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            17468..18535
                     /locus_tag="PC503_001104"
     CDS             17468..18535
                     /locus_tag="PC503_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF2527115.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            18705..20606
                     /gene="cooS"
                     /locus_tag="PC503_001105"
     CDS             18705..20606
                     /gene="cooS"
                     /locus_tag="PC503_001105"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2527116.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            20599..21072
                     /locus_tag="PC503_001106"
     CDS             20599..21072
                     /locus_tag="PC503_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2527117.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            21047..22273
                     /locus_tag="PC503_001107"
     CDS             21047..22273
                     /locus_tag="PC503_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2527118.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRILKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(22412..23599)
                     /locus_tag="PC503_001108"
     CDS             complement(22412..23599)
                     /locus_tag="PC503_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2527119.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRIVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            23872..24696
                     /locus_tag="PC503_001109"
     CDS             23872..24696
                     /locus_tag="PC503_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2527120.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GSNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            24825..26090
                     /gene="gluD"
                     /locus_tag="PC503_001110"
     CDS             24825..26090
                     /gene="gluD"
                     /locus_tag="PC503_001110"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF2527121.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            26303..26893
                     /locus_tag="PC503_001111"
     CDS             26303..26893
                     /locus_tag="PC503_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2527122.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            27224..28357
                     /locus_tag="PC503_001112"
     CDS             27224..28357
                     /locus_tag="PC503_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2527123.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMREEHKINCEFLGLIPKDSDKIGVGIEYYDSLLND"
     gene            29273..30295
                     /locus_tag="PC503_001113"
     CDS             29273..30295
                     /locus_tag="PC503_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2527124.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            30591..31511
                     /gene="pyrB"
                     /locus_tag="PC503_001114"
     CDS             30591..31511
                     /gene="pyrB"
                     /locus_tag="PC503_001114"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF2527125.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            31550..32242
                     /locus_tag="PC503_001115"
     CDS             31550..32242
                     /locus_tag="PC503_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF2527126.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            32235..33137
                     /locus_tag="PC503_001116"
     CDS             32235..33137
                     /locus_tag="PC503_001116"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2527127.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            33222..33806
                     /locus_tag="PC503_001117"
     CDS             33222..33806
                     /locus_tag="PC503_001117"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF2527128.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            34020..34946
                     /locus_tag="PC503_001118"
     CDS             34020..34946
                     /locus_tag="PC503_001118"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDF2527129.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(34998..35888)
                     /locus_tag="PC503_001119"
     CDS             complement(34998..35888)
                     /locus_tag="PC503_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2527130.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            36076..37107
                     /locus_tag="PC503_001120"
     CDS             36076..37107
                     /locus_tag="PC503_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF2527131.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            37401..38276
                     /locus_tag="PC503_001121"
     CDS             37401..38276
                     /locus_tag="PC503_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HDF2527132.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            38294..39784
                     /gene="cls"
                     /locus_tag="PC503_001122"
     CDS             38294..39784
                     /gene="cls"
                     /locus_tag="PC503_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2527133.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            39977..40261
                     /locus_tag="PC503_001123"
     CDS             39977..40261
                     /locus_tag="PC503_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF2527134.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            40294..41922
                     /gene="groL"
                     /locus_tag="PC503_001124"
     CDS             40294..41922
                     /gene="groL"
                     /locus_tag="PC503_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF2527135.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTESAVADLPEKEDAGMPGMGGGMPGMM"
     gene            42184..42924
                     /gene="larB"
                     /locus_tag="PC503_001125"
     CDS             42184..42924
                     /gene="larB"
                     /locus_tag="PC503_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF2527136.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            43008..43742
                     /gene="larC"
                     /locus_tag="PC503_001126"
     CDS             43008..43742
                     /gene="larC"
                     /locus_tag="PC503_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF2527137.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            43772..44191
                     /locus_tag="PC503_001127"
     CDS             43772..44191
                     /locus_tag="PC503_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF2527138.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCSES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      44251..44352
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            44573..46108
                     /gene="guaA"
                     /locus_tag="PC503_001128"
     CDS             44573..46108
                     /gene="guaA"
                     /locus_tag="PC503_001128"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF2527139.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            46647..48077
                     /locus_tag="PC503_001129"
     CDS             46647..48077
                     /locus_tag="PC503_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2527140.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFLLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVSIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKSDGMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(48225..48575)
                     /locus_tag="PC503_001130"
                     /pseudo
     CDS             complement(48225..48575)
                     /locus_tag="PC503_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            48570..49091
                     /locus_tag="PC503_001131"
     CDS             48570..49091
                     /locus_tag="PC503_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2527141.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKIFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIMSGILGIFFYL"
     gene            complement(49220..49456)
                     /locus_tag="PC503_001132"
     CDS             complement(49220..49456)
                     /locus_tag="PC503_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527142.1"
                     /translation="MLECFIAKDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSKKFCQEAYDWFVENQ"
     gene            complement(49766..53194)
                     /gene="uvrA"
                     /locus_tag="PC503_001133"
     CDS             complement(49766..53194)
                     /gene="uvrA"
                     /locus_tag="PC503_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2527143.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEALNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNHLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQAPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            53513..55747
                     /locus_tag="PC503_001134"
     CDS             53513..55747
                     /locus_tag="PC503_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2527144.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            56003..58033
                     /locus_tag="PC503_001135"
     CDS             56003..58033
                     /locus_tag="PC503_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527145.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            58030..58482
                     /locus_tag="PC503_001136"
     CDS             58030..58482
                     /locus_tag="PC503_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527146.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            58484..59539
                     /locus_tag="PC503_001137"
     CDS             58484..59539
                     /locus_tag="PC503_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF2527147.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            59606..59914
                     /locus_tag="PC503_001138"
     CDS             59606..59914
                     /locus_tag="PC503_001138"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF2527148.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            60018..61283
                     /locus_tag="PC503_001139"
     CDS             60018..61283
                     /locus_tag="PC503_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF2527149.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            61371..62087
                     /locus_tag="PC503_001140"
     CDS             61371..62087
                     /locus_tag="PC503_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2527150.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHELEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(62282..62575)
                     /locus_tag="PC503_001141"
     CDS             complement(62282..62575)
                     /locus_tag="PC503_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF2527151.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(62581..62796)
                     /locus_tag="PC503_001142"
     CDS             complement(62581..62796)
                     /locus_tag="PC503_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527152.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
BASE COUNT        23981 a         7270 c        10459 g        21499 t
ORIGIN      
        1 agtaaaaaat aaaaaaatgg aagtgattga gatgagtagt atattgttgg ttgaagatga
       61 tttaagtttg atatatggat tagaatattc tatacaaaag aatggattta gtgttgatgt
      121 agcaagaaca gtagaagaag cattgcaaat ttataaagaa aaaaattatg atttactgct
      181 tttggatgta tccttacctg atggtgatgg ttttgatatt tgtaaaaggg taagagaagc
      241 ttctaatgta ccaatcatat ttttaactgc ttctgatgaa gaagtaaatg tagtgatggg
      301 acttgatatg ggtggagatg attacataac aaaacctttt aaattaaatg agttaatttc
      361 aagaataaaa gctttactta gacgttataa ttttacaagt gaaaatgtaa ctgaactaaa
      421 atcaaataat attactgtta aattacttga aaatcgtgtt tttaaaaatg aaattgagct
      481 tgaacttact acagcagaat ataaattatt atgcttactt atgaaaaata aaaatattgt
      541 acttacaaga aaaaatatat tggataagtt atgggatgga aatggtagtt ttgtagatga
      601 taatactctg tcagtatatg taagaaggtt aagaaataag attgaagata atcctgaaaa
      661 tccaaaaaat ctattaacag ttagaagaat gggttacaaa tggaatgtta taaagtgagg
      721 gtgttaatat gaaggtattt tctaataaag acataaaaat attttttttg gtgattatat
      781 ccgttttatt gatgtttata gtagtaggtc aaatagtagt tataaatata actaatgatt
      841 ataaaagtgc actgttagaa catgattata atatagctgg atacttaaat agtatgggtg
      901 ttgataaatc aaaaatacca gcagtattta ctactaatga agataaatat actttaaaag
      961 gaaaagaaat cttaaataca gctagatatg actttggtac agatgatagt tttatgccaa
     1021 gtgtgaaatt gtttcaaggt aaatatataa aaactatgtt tttgtattta tttgtgttct
     1081 ttactatgat tatttttata ttgtatgtgt atttttttag gcaacagaac aagatagaag
     1141 aagctagtta taaaattgat tcatttatga atggaaatat aaatgtacgg ttaaatactt
     1201 atgaagaagg tagtttatca aagttatttg gttcaataga tgctatgtca acatctctaa
     1261 acacacatat attgaaagaa aagcagaata aagaatttct taaaaataca atttcagata
     1321 tatcacatca actaaaaact ccacttacag cattgatgat gtataatcaa atattgcagg
     1381 aagagagtca taatagtgaa attgttgaga attttgtgca gaagagtcaa aatgaattag
     1441 agcgtataga atcattgata caaaacttgt taaagattac aaagatagat tcaaagacaa
     1501 taattcttaa caaagctagt gttaacgtaa aaaagttgat tactaaaatt ttatatagtt
     1561 ttgaaactag agcagaaaaa gaaggaaaga gtatctctat aagaggtcta gaaaatacaa
     1621 acttgttttg cgattatgaa tggatatcag aagctttaag caaccttata aaaaatgcat
     1681 tagataatac aaaagagaac gataaaataa tgatagaatg ggttgaaaca cctataacaa
     1741 ctattatttc agtgagtgat accggaaatg gaattcatat tgaagatata catcatatat
     1801 ttaaaagatt ttataggagt aagttttcaa aaagtaatca aggccttgga ttagggttgc
     1861 cactagttaa atctatcata gaacagcaca atggaaccat aactgtagaa agtaattttt
     1921 tacaaggaag tacatttact ctaagttttt taaagcttac taatatgtaa gataggatac
     1981 atcttacagt aaggtgtatg aattattctt atattaatca tcagaaagga gatagagcaa
     2041 atggatattc ttgtggttaa taatttatgt aaaacatatg gaaatggata tacaaaagta
     2101 gaggcattaa aagatgtatc atttacagtt tcaaagggag agtttgttac tgtagttgga
     2161 gaatctggct caggtaagag tacattatta aatcttttag gaggtcttga tactccaacc
     2221 tcaggaaaaa tatttgttga tggtaaagaa atatgttcaa tgaaagaaga aaaacagact
     2281 atttttcgac gtcgtaatat aggttttatc tttcaatcat ataatcttat acccgaatta
     2341 actgtggaac aaaatataat atttccttta ctactagatt acaaaaaacc agacactatt
     2401 tatctagatg aagtattgac aattttaggt cttaaagata gaaaaagtca tcttccaaat
     2461 caattatctg gtggtcagca acaaagggtt gcaattggaa gagcattgat tacaaagcca
     2521 tcaattatat tggcagatga gccaacagga aatcttgaca gtaaaaatag cagtgatgta
     2581 atttcacttt taaaagtgac agcagaaaaa tataaccaaa ctattattat gataactcat
     2641 aatacaaata tagcttctac agcagatagg atactacagg tttctgatgg aatgcttaaa
     2701 gacctagggg tgaatagaga atgagaagct atttagaact agtaccacaa tatgcaaagg
     2761 tacataagaa aaaaaataga actacaattt tatgtattgt cattgcagta tgtttagtta
     2821 ctgctatttt tggactagca gacatggcta tacaatgtca aaaagtacaa tttataaaag
     2881 atgatggaaa ttggcacata gtacttaaaa atcttaatga agaagctata tcagaaataa
     2941 gtagtagagt agatatagct cactatggta gaggacaagt cattgataat ggagagttta
     3001 aatcaaagga gattttgata caaggtttag atgaagattt agcaaaacaa ttaggtctag
     3061 aaataataaa aggtcgttat cctgttgtgg agaatgagac tttaatagat gtagatgcag
     3121 ttaaaagctt taatctaaaa gtaggagatt ttatcaaaat aaaattagca gatggtagaa
     3181 ataaaaatta taagatagta ggtgaatatt catcattatc aagattaaga gcctcagata
     3241 agcatggatt aatgctttca atattaggta cacaagctat caaaaaatca gaaacatatg
     3301 attattatta tattacattt aaagacaagg ttaatattag aaaagctact tctgatatta
     3361 agaatacctt caatttaagt gataaacaaa tcggtaaaaa tgaaaaatta ctttctatta
     3421 taggtcaagg tgactctgat tattctaaac cactttactt aacagcagga ggacttttta
     3481 tacttgtgtt aatagcaagt attatcatga tatataatag ctttaatatg ggtgtaatag
     3541 agagaataaa gttttttgga ctattacgtt gcttgggagc atcaaaactc caagtcaaaa
     3601 aatttgttgt tttagaaagt ttaattctaa gtgtaaaggc tattccacta ggattgttat
     3661 taggatgtat tgtaaccatt atatcctcta tatttctcaa atatgtgaat acagagttat
     3721 ttggttcgat gccaatttta aaggttagct ttattggtat tgtgtttgga ataatagtag
     3781 gatttttaac agtaatatta tcagctattg ttccagcaaa aaaagcttct ggggtgtctc
     3841 cactaagtgc tatacgtggt aatctaatgt tcaaagaaat tttaactagt ggaaaagcaa
     3901 gtaaaattgc taacgcagga agttctaaaa ttgatgtttc tatgggaata aatcatgcct
     3961 tttcaagaaa aaaatctttt atacttatga cttcttcatt tgctattagt attgtattgt
     4021 ttttaggttt tagtgtattt atagacttta tgtatcaggc acttaaacct ataaaaccag
     4081 aagctgctca tatatctatt gttgacgctg actttaagtc tgttcttact aaagacgata
     4141 ttaatgaaat aagtaatatc aaaggaataa aaaaagtata cagtagaatg atgacggatg
     4201 tagaggctac atacaataat aaggaggcaa catctcagct aatttcttat gaaaaaaatc
     4261 aatttgactg ggccaaaaag tatctagtaa aaggggaaat caatgaagat aaattagagt
     4321 cagaaaatat cggattggta gaagaaggtc atgggtttaa tattggagat aagatatata
     4381 ttaaaaatgg aaattctaag aaagagatag aggtagcagg tatactttct tcaatttcat
     4441 ttgatgttaa agacaaatat attggaaata ttataacatc tgaaaatact tttactagta
     4501 taacagatat aaaagactat ataataattg atactcaagt tgatgaagat gctcctgaag
     4561 atttaatcca aaatataaga aatgttctag atgataattt agaggttcga gataagcgac
     4621 aaggtaactt agaggctaaa aattcatttt acactatggc agtttttgta tatgggtttg
     4681 tatttataat tgcgattata agtatgttta atatcataaa cagtatgaat ataagcgtta
     4741 caagtagaat aaattactat ggtattatgc gtgcaatagg catgtccaat aagcaattaa
     4801 gaaaaatggt aatagtagaa tcaagtacat atgctgtaag tggctgttta ttggggagtg
     4861 tacttggatt aatattacat agatatatat ttgtatcctt agtaacatta aaattccata
     4921 tagactggca aatacctttt gatttactgt ttatcattgt agtaactatg ataataataa
     4981 ctttgcttgc agtaagaaaa ccaattaaaa agatttgtga attagacata atagaggtag
     5041 taaatgcaca ataaatataa gtagtaattt aaatagaggt agtaatttaa ataaaaaatc
     5101 gaagtaaata tgaaatagaa aatatctttc ataatttact tcgatttttg tgttatataa
     5161 tttactttag ataagttcca tcttcatctt gataaattaa gtctttcttc ataagtactc
     5221 caagagcacg tttaaaattt tcttacttga attaaataag atagaaatat ctttaggatc
     5281 agatttatca ttgaatctca tatatccatc tgaaccttct aaatagctta aaatcttatt
     5341 ttctaaggta tcaagttcat cttttctgtt tcctctagga gaaagtccta atttaccatc
     5401 atcgtatatt tttataacat gtaaattttc aagaacatcc ccagctttta attctgtaaa
     5461 gtattcatta tgaaggatta caccagcata tttattgtca acacatatca tagcagagtt
     5521 gttggtttgg aatccatata caactccatt tacaacatct cctacattgt aagtatggtc
     5581 tgtttctaaa tatgaatcta tgtctgtagt agcagctatt cttccgcttt tatccaagta
     5641 tatatagaat aaatattttt catctctaaa caatggataa gtcttagctt taaaaggaac
     5701 tagtatgtct tttgtaagtc ccatatctat aaaagtacca atatccgtgt tatcaactac
     5761 ttttagatac gtaacatctc catttctaat tatttctata gtattagaaa aataattttt
     5821 aaatagtttg taaaatatta ttgaattttt tctctcgaaa tatataattt agaatcttct
     5881 gatttatttt tatgctcgat ttccttattt tttttcataa atatatatag aggagctatt
     5941 aacaacattg cccctaatcc tattaaaact ctattttgag ttataggttt tgaaatatct
     6001 tctgcccaag cttgttgtaa caaccataag ctacctaaaa tagctaccat tggtataaca
     6061 ggaccaaatg gaatcttaaa agaggcctta acatctgttc tttttcttaa aactattact
     6121 gataaacaag ttggtatgta ctgagcaaat cttgcaatta cactcattac tgcaagttgt
     6181 tcaaaacttc cagttagcac aagtggtata caacaaatta aagatattat tattgctaca
     6241 tatggagcac catatttatt tgtttttcct ataaatgcag gaagagaacc ttcttctgct
     6301 agagaagaac cacatttagg agttactatt gatgaaccta tatttatacc aaatatagat
     6361 attaatgttg ctacagatat gaaaaattta ccataattgc ctaaaaatac acttgaagca
     6421 tctgcaattg gaatactgtt ttcaaatagt ctatctccaa gtatacccat acagacaatt
     6481 tgaattaata tataaattat tgcacatata aatattgtgg ttattaatgc gactggaaga
     6541 ttttttttag gattttccat ttctccactt gccacaataa atgattcaaa gccggtaaat
     6601 gcgtaaaata ctaatataat ggctggaccc atactagagt taactacatt tcctgaagga
     6661 acaatattta caaattttat aaagaatatt ccaactatta taaaaactat taatggtact
     6721 aatttagcta tagttattac attattcatt atctttgtgc ttttaattcc aaataagcta
     6781 tttattgaaa gtagtgttac gagtattgca gctatataac ctttgtattc agtggcagat
     6841 tctggccaaa atgaacctaa agctgttgca aatcctactg ctagagtaga ccatgatata
     6901 attctaataa cccaagacat tgtaccaact tcaaatccta taaaatctcc aaaagctttt
     6961 ttggagtata gatatgctcc tccattctta tcaaacatgc ttccaacttc tgcaaaacat
     7021 aaaagtattg atagaactaa gagtgtagca aaaatgtata taaacatact gttttgacct
     7081 gctagattat aaactttacc tggtagtaag aatatacctg aacctattat gctattaatc
     7141 cctaataata tcatactaaa tagacctaat ttcttagctt tttccatatt aatttatctc
     7201 ctattctttt attaattact gtactaatta aaatacaaag tattcattac atgcatcata
     7261 acacctattg gtaaacaatc ttcatctata ttaaagctag aggtatgaag aggtgaaatt
     7321 aagccctttt cctcattttt acatcctaaa tggaagaatg ctcctttaca atgttctgtg
     7381 taaaaagaaa agtcttcacc acctaaagac gggtttggtc tcaatataaa tttttcctct
     7441 ccaagtaatt ctttagtatt tgatataact gtatctacta attctttttc atttataaca
     7501 gcaggatagt tttcatcact tacatgtaaa gtcccaacac aaccaaatgc agatgcagtg
     7561 tctccaacaa ttttagctat tttatcaatc ataaagtttc ttgttttgct atttaaggtt
     7621 cttaaagtgc cttctagttt tacatcttca catattacat tgtgtgcatc accaccatat
     7681 attttaccta tagtcaaaac agcagcatta tttggttcta agtttctact tattatagtt
     7741 tgtaatgatg taacaatttg tgaagctgta actattgcat caataccatt ttcaggatat
     7801 gcaccatgag ctcttttacc tttgatactt atttttatag tgtctacact agcatttaat
     7861 gtatcatatt ttatttcgat aaatcctgtt tcgatatgtg gcataacatg aagtccgaat
     7921 atataatcga ccttaggatt ttctaaacat ccatcttcaa ctaagaattt tgctcctcca
     7981 aaaccttctt ctgctggttg aaataagaat tttacattta cattaagttt atcttttatt
     8041 gaatgtaaaa ctttacatgc tccaagtagc atggttgtat gtgcatcatg gccacaagca
     8101 tgcatttttc cagaatgtat tgatttataa ggtatgttgt tttcttcttc aataggaaga
     8161 gcatccatat ctgctcttat acaaatcgtt ttatctgcac tttcttttaa aatatatgcc
     8221 ataattccat tgtgttttgt aaattccata taatcaattc cgatttcttt taaataagaa
     8281 attaccttct gtttagtaag attttcttca agagctaatt ctggaatttt atgtaattct
     8341 cttcttatgt ttataagcca tggttttata gaattacaac tttctattac aaaatctttt
     8401 cctaattctt tggtttgata ttttaatttc aaagcctgtt gcatttttat tcctccaatt
     8461 gctttttatt gttttattaa tataataagc aattattatg ccataatttt cgatggagaa
     8521 ctttgttttt tataagaata ttgaataaat ataatcattt atctatatgt atagtataaa
     8581 aaatgattgc atagtttcaa ttttcagtaa aaaatattat tttgaagaaa atatatttta
     8641 tatgctagtt tatataaaaa aaataggaaa taaaaaaatt atcctattcc tattaattcc
     8701 tattatttat gtacaaaata aattataatt tcagggtact tgaaaaataa aaaaacctat
     8761 tgaaggagta ctttaatcct gaatagattt ctttgtttga taaattataa ttttatagac
     8821 ctttatattt taatttattg taaaaatctt ctcctttttg agttatttta cttccatatc
     8881 ttcctgaact acaaattata agttcttctt tttttagata ttcaaatatt tttttaattt
     8941 ttccttctgt aatttgaagg ttcttatcga gtagtgcttt taaaattaat cctctaccaa
     9001 taccaacatc tgattcctta tttaaaatta gtatctctaa tatattcaat atatcattct
     9061 tactatattt tagttttaat gatgtatttt tgttatctga agaccttaag tttggaggta
     9121 aatctttctc taatacaata tcttcacaca taatgtttaa ataggatgta acattttgga
     9181 gttctcttat attacctttc cacatatagt tttgtataag tttttttgct tctggtgtga
     9241 ttactaattt cttattaatt aaatcttcca taataattaa tatgtcttct tttctttctc
     9301 ttagaggagg tatatttatt ggaattgtat ttaatcgata atataaatcc tctctaaatt
     9361 ggctattatc aatcatttgt tctaaattct tatttgtagc agatatgatt ctaacatcta
     9421 tattaattac attgtgagac ccaacaggca ttatctgctt ttcttgaaga actctaagta
     9481 gttttgtttg taattctaaa ggcatatcgc ctatttcatc taagaatatt gttccattat
     9541 tagcaagttc aaataatcct tgttttccat cttttagacc tccagtaaaa gttcccttgt
     9601 catatccgaa tagctggctt tctaataaat tttcaggaac ggctgcacaa tttactgcta
     9661 taaagggttg attttttcta tttgagttgt tatgtataga ctgagctatg agttctttac
     9721 cagttccact ttcacctctg ataagtatgc ttaagtcaga tttagaaacc ttcttagcta
     9781 aatctataca ttcaaacatt ttaggactat ttgtttttat atccttaaat gtatattttg
     9841 ctatttgtcc tttttctctt aattttttag tgagattttg ttctaatttt tttatgtatg
     9901 ttatttcttg taaactataa tatgtgccca ttttttcatc tctattgtat atgttttttt
     9961 tatttacatt tatatatttc ttattgaata cgacaacttt atctagtatc tctttctcac
    10021 tcaataaaac ttttaaacta tctacaaata tatcctcaat gtattttcca tatatatcct
    10081 catttatgtc taaaatatct tttactttac tattatatgt atttatttca ccatcttttg
    10141 aagtaaataa tataccatct tttgataaat tcaatattgt atctaattct tctattttta
    10201 aaaataattc cttatattta tcttttatac cagtatctaa acttattatt tcttctgagt
    10261 atttaactag attagattgt atttcctttg aatcaatttg taataaattt attatttcta
    10321 taaatgtaga aatatctata tatctgtgac ctaaatcaaa tatatctgag ataaagctag
    10381 gtactttttc tggaactcct ggagttatag ctatttttat atttttatag ttattatcat
    10441 tcatatatgg aattggtcta atattagtca ctccaatttt ataaaataaa cttatagttt
    10501 ctagagtagt ttcatcagaa tcatttacga ttagaacatt tgtaccctgt ggtaaagata
    10561 gtagattata aattttatct tccctaaaag ttcttcttac cacaatcact tttttcttat
    10621 ctagtatatt atttataatt ttgtctaatc tttctactga cattactaat atcacatcat
    10681 catttataat atcattatca tttatttcat ttatgaagta tctattaata tttatagaat
    10741 ctccaaaaac taatttcaaa ttattttcta aaaagtctat taaatctttt ctactatcat
    10801 ttaccagagc tactgatttt ttcatttatt tctccttata taataaatag tttccaacaa
    10861 aatagttgta taaagcaata taattttgat aatttaaatt tatcaaataa aaaagaaagt
    10921 gtctataatg actttataaa agttgcatta agacactttc tttcttataa ttaaaaatct
    10981 tgtcaccaaa tccccctaat tgttgcttaa aacttaaact gtatgtatat ttttcatttc
    11041 tattcgatta aattataata tacacccaaa aaaatttatt ttaataaatt ctattgataa
    11101 tataattttg taaatataga attatattaa aataaattat atattaaaat atatatgtat
    11161 aagtttattc tgcgtcagta gaatgaattt gtcaagttta atttagttgt aattttatct
    11221 tttattaaaa ataatataaa ttaaaacata taaataaaat attttataca atatattgta
    11281 aaggaggtaa ctttgatgaa agcagaaaaa acaagtatat atccaattat taaaaataat
    11341 ttaaacaaaa tatcaattgt tgaatataaa aagggtcaaa gatttgtagc atcagataaa
    11401 gacttacaag aagtgttctt tataatagag ggagttgcat tagtggagtg tactactaga
    11461 ggaggaaata aatttcttgt tgacattgta cctgaaaatg aatttatagg caaaattagt
    11521 tacatatatg aacataattt gaaatgtgat atatttgcaa agaccaatat aaaattattt
    11581 cgatttgaaa aaaatgtatt tgaagagttt tatctcaaac cagattttat tgcactattt
    11641 cacagaaaat gtacaagaag aatatatgaa ttatataaaa ccagaatggt aagagaacta
    11701 ttttcttgca cagaagttat tgcctattgt atatcaaata aacaagaaaa taatgtctgc
    11761 aatataaaag ctattcgtaa tttcagtgaa atctattcaa ttagtagaaa aagtagatac
    11821 cattctctgc taaagttaac tgaaaaggag atagtaaaaa aaatgggtaa tacatatgaa
    11881 attttaaact atgatgaatt acataaattg gcatttgaag taaaagaatt tttggaagat
    11941 gagtaaaaat tgttacttaa tcaaaataaa gtataataat ttctgtaaaa aatagaaata
    12001 gtctcactga aaatcaaaaa tactttagtt attttcaatg agactgttta gaaatattgt
    12061 atacttataa tgtatagtat aattattaat caatttcctt tactatatta atagcccatt
    12121 ttttagataa tgctctagga acaccaaata taaacttaac cacttcttca ctataagtga
    12181 gcaaaacgag tacaaatata ggtgcacctt taaatgcagc tataaaagtt agaggaatag
    12241 aagctaacca catacatcct aattctaaaa atagagcata tttagtatct cctccacttc
    12301 ttaaaatacc aattataacc aatgtattaa aagatttaag agccattagt attcccatta
    12361 taaagaatat cttagttata tcagaagcta agctatcaga aacactaaac atttttaata
    12421 ataatggtat atttaaaatt aaaataattc caagtattaa accagctgaa aatacaagta
    12481 tagaaaactt tttagcatat tcaatggctc ttttaatatg gtcagctcca agttcatttc
    12541 caagcataat agatgcacca gatgcaatac atacagctgt cattatgaag aaattacctg
    12601 tactggttgc tatctggcta gctgctatag cagaagtacc agctcttgca tatgcaacag
    12661 aatacaggac agttccaatt gcccatacag agtcatttac aaatatagga aagctttttg
    12721 atgaaaaaga ttttataaaa attttatcaa tagcttttag attttttaga ccaaacttta
    12781 atatatagtc ttttttataa aggtaaacat aagtaatcat taaaattaat tcacatattc
    12841 tagcaataac agtagctaga gcagcacctt ttacacccaa tgcaggaaga ccgaagttac
    12901 caaatataaa tccataattt aaaataacat ttgttacaag tgcaaatgca ctacaaatca
    12961 tacctaactt aggatttcta acacctcttg aaccagtgct aaatacagta cttacagcaa
    13021 ttaatggata actaaatact gcaatactaa agtaatctat acaaagtttt accacctcag
    13081 aatcatacga aaatatgtgt ataattggct ttggtgttag taaagcagga ataacaaata
    13141 caaaacttaa aacaattgcc aatacacaag taagacctgt gacttttctt atattactca
    13201 catccttctt tccataaaac tgtgaaataa aaactccagc acctcctgtg ataccagata
    13261 aggacatatt aaaaagaaag aaaaattggt ttgcaactcc aactgaagct acagatgttt
    13321 cccccaaact acttatcata attgtatcta ttacatttac agaagtagaa attaagttct
    13381 gtatgataat aggtatacat aaagatagaa gtattttata aaatctttta ttttcgtctt
    13441 ttaaagaaaa tagttcttgc aaataatcct ctccttttta cataaattct tcccactcat
    13501 catatagaga ggcaaggtta ttttctaaat taattttttc ttggctaact tctttagctt
    13561 tatctggatt agagtatact tcttcttgac ataaaagtat atctaatttt tcaatttcaa
    13621 tctctaactt ttcaatttct ttttctatat tttgtctttt tattctattt ttcttttcta
    13681 tttctctttg ttctctctct tttctttttt catcttttat ttgagttcta gttttttctt
    13741 ctttttcttc tataatactc atctcttgga tttgcctttt tttatctata taataatcat
    13801 aatttcccag atattcagta attccatttt catctaaaac taaaatttta tcaacaacag
    13861 tatttagaaa gtatctatca tgtgatattg taaatatagt cccatcataa ttagttaatg
    13921 cctcttcaag gacttcctta gaatcaatat ctaggtgatt agtaggctca tctaataaca
    13981 ataagtttgc atttgatagt ataagtttaa gtatggcaac tctagctctt tctccaccac
    14041 tcaatgtaga aatcttctta aaaacttctt catctacaaa taaaaatgcc cctaacatat
    14101 ttctcaaagt agtttgagta agatgagtat tattttccca aatctcatca attattgtgt
    14161 tatctaaatt aagagttttt tgttcctgat ggaagtagga aacatgtaca ttagttccaa
    14221 atttaatatt gccactaaga ggttgtagtt cattagttat tattttaaat aatgtagatt
    14281 tgccaacacc atttgcacct ataagtgcaa ctttttcccc tctatatata tctaaatcca
    14341 agtctttaaa aagtattctt tctccataac ccatagatac atctctaatt tgaagaacat
    14401 cattaccact ctggacagaa ggcgtaaatt gtatacgagc ttttttccta taagcttctg
    14461 gtttatctaa aacgtctacc ttgtctaatg ctttttcttt acttcttgca cgctttaggt
    14521 gtttttctct accataagct tttagtcttt caattgattc ttcttgcttt tttatttctt
    14581 tttgttggtc ttcaaatttc ttaagctcta gttctttttc tattttagat aactcaacaa
    14641 atttagagta gttaccatta tatactttaa gttttttgtt gtgaacttca aaaattctat
    14701 ttacggattg gtctaagaaa tatctatcat gagatattaa catgacagtc cctttatatt
    14761 gttttaaaaa tacttctaac cattctattg cttcagagtc taagtggtta gtaggttcat
    14821 caagtaacaa tagagttggt ttcttaagaa gtaattttcc taaaagaact ctagtttttt
    14881 caccaccaga aagtatgctt attggcttat ccatatcatt gtcactaaat cctaatccct
    14941 ttagaactcc tttggcttca gatttatatc catatccatt taaatctgaa aataattcta
    15001 gtttatgtga atattcatcc atgatttttt ctataattgg agagtttgtt tttgtacttt
    15061 cttcagatat tttaacctcc aattctctta aataggattc catttctatc aaatttttaa
    15121 aaacttctag tacttcttcc aaaatagtat tatccgaata aaaattggta ttttgttcta
    15181 aatatccgat ttcacaatct ttagaagtgt aaatatctcc actatcatat ccataaattc
    15241 ctgaaattat tttaaataaa gtagtttttc cagtaccatt aacaccgatt ataccaattt
    15301 tatcgccttc atttactgta aaactaatat tttctaatat agaatctata ccaaaacttt
    15361 tatttaagtt attacatgac aaaacaatca taaatttcta cctccttgaa ctatctaaaa
    15421 ttataatgtt ttgatataat ataatcaagg ttatatgtat tagttttgaa aaagaaatat
    15481 tttattgtga atcaaacaaa aaagaggaca cttttaggag gtgaagatgt tgggaaataa
    15541 aaatatatca atggcagtta taagaaggct cccaaaatat catagatatc ttggagactt
    15601 attagatagg gatatacaaa gaatatcttc taaagaattg agtgatataa tagggtttac
    15661 cgcttctcaa ataagacaag atttaaacaa ctttggtgga tttggacaac aaggatatgg
    15721 ttataatgta gaagctcttc atactgagat aggtaaaatt cttgggttgg atcgaccata
    15781 caacgcagtt cttgtaggag caggtaactt aggacaagct atagccaatt atgcaggatt
    15841 tagaaaagct ggattcgaga taaaagcttt atttgatgca aatcctagaa tgataggttt
    15901 aaagataaga gagtttgaag tattagattc agatacttta gaagacttta taaaaaacaa
    15961 taatatagat attgctgtat tatgtatacc taaaaatgga gcacaagaag ttattaatag
    16021 agttgtaaaa gctggaatca aaggtgtatg gaattttgca cctttagatt tagaagttcc
    16081 gaaaggtgtt atagttgaaa atgtaaactt aacagaaagt ttatttacct tatcgtattt
    16141 aatgaaagaa ggaaagtaga caacttaaac atattaataa tgagcagttg tgaagagtat
    16201 tgagaaagtc agaagattta atattaaatc ctctggcttt ttgaaatatt aggataaaaa
    16261 tttaaataat gtatggaaat aaacaatatt aaggagagtg gtttttgtgg aggaattatg
    16321 gaaaaaggca attgaatttc atggtcatga atgtccaggg ttagctatag gatttaaagc
    16381 agcacttgca gcaagagaat atttaggatg taaacagtca ggagatgagg aaattgtatg
    16441 tatttctgaa aatgatgctt gtggaataga tggtatacaa gtcgtgctaa gttgcacaat
    16501 gggtaaagga aatttactac ttaggatgac tgggaaatca gtatatcatt tctttaatag
    16561 ggaaaatgga aaatctataa gaatatatgt aaagtcaaag ccatttcaaa tggatagaga
    16621 aggatacaaa aagtacttat tagaaagtga ttttgaagaa atatttgaga ttacagatac
    16681 taagttaaga cttcctgaaa aagcaagaat atttaaatct cttaaatgtg aagtgtgtgg
    16741 tgaatttgca tctgagcaat atataaggat tgaagaagga aagaaagtat gtcttgattg
    16801 ctttaataaa tatgaaagat tttatgagga gtattaaaat tataaattag attaaagtta
    16861 aaagtattag atatgtgcta acagtatttt aagatgaatt aggtagcaac ataataaagt
    16921 atataaataa tattaattga atcatacata attaaaaaga ggctgattag tatttataaa
    16981 ataaaatcag tctctttatg aataacgaat tattattctg gttgaggtgc atctacagga
    17041 caagctcctg cacaagaacc acagtctata caagaaccag catctataac atatgcgtcg
    17101 tctccagctg atatacagct aacagggcat tcagcctcac aagcaccaca gcttatacaa
    17161 gcgtcagtaa ttttatatgc cattttgaaa tcctcccttt tatatgtatt gtaattcaat
    17221 aacattataa caaatattat tgaatataac aattaaatta attctacaac aaaaacttta
    17281 ttatgatatt cttgttttaa agttttacaa taaagtttaa tctgcttata tttttattta
    17341 ttttaaagaa gtttatttta aaaataaaat taaatttaaa aagttatgta ttgattatat
    17401 ttaaaaatgt tatactctaa aaaagtatat tttatttaaa aatttattaa tacaaaggag
    17461 atttactatg aaaaataaat tagtttacat atgtattatg agtctattgc tatttgtagt
    17521 aggatgttct aataatccaa ataaggaaag taccattaaa aaagactcta agaataacca
    17581 aagccaagtt aaagaagaaa aaagagaacc tgtgaaaaaa gatataacta taagtttcgc
    17641 tggtgatgta actatgggga actataaagg ttcatcatat tatggcagtt ttgaccatga
    17701 atttaaaaga caaggagaag attacaatta ttttcttaaa aatgtaaaac ctgtatttga
    17761 aaaagatgac ttaacagtgg ttaatttaga aggtccactt actacagcgt caaatgcaaa
    17821 agaaaaaaaa tttgcattta aaggaaagcc tggatatgta aatattttaa aatctggaag
    17881 tgtagaggca gtaagtattg caaataatca ttcagaagat tattttgaag aaggaatgaa
    17941 agatacacag tttatattgg acgagaataa aataaattat tttggattag ggaaagatgc
    18001 tgttgtagat gtcaaaggaa ttaaagtggg tctattaggg tataatggat tatcaactga
    18061 atataatgaa aaaaatttaa aacaaatgga agatgatatt aagtccttaa aaaagaaatc
    18121 ggatgttgtt gtagtgtact ttcattgggg gatagaatta gattattatc cagataaaaa
    18181 acaaaaagat tttgctcatt atgctataga caagggagca gatttagtta tggggtctca
    18241 cccacatgtg attcaaggaa tagaaaagta taaaaataag tatatagctt atagtctagg
    18301 gaatttttgc tttggaggaa ataagaatcc ttctgataca gatagttata tatatcaaca
    18361 aacctttact ttttcagata ataaattaac ttcaattaaa gagccaaata taataccaac
    18421 ttcaataaca tctagtaact ccagaaataa ttatcaacca aaaatattgg atggaagtga
    18481 gaaggataga gttttaaata aacttgaaaa aataagcaaa gatttaaata aataaaatgt
    18541 aaaaaaaaat aaatatatat atttatttta ataatttata ttttgtttag ggtatggtaa
    18601 atcgtggtat taaataagta gattttaata gttaaattat agtcaattat aataaagcta
    18661 tttaatctac ttttttaata taaaaatata agggggaatt tgtaatggct tgtaacactt
    18721 gtaaaatgtg cgaaagtgca gacaagaaat tagaaagttt tgtagcttca aaggatgttg
    18781 aaacagcatt tcatagaaca gaagatcaga aagttaagtg tggttttgga cttcaggggg
    18841 tttgttgtag actctgttca aatggaccat gtagagtaac tcctaaatca ccaagaggta
    18901 tatgtggagc agatgcagac actatagtag caagaaactt tttaagagca gtagcatcag
    18961 gagcagcttg ttatttacat gtggtagaaa atacagctaa gaatttaaaa aatgttggaa
    19021 taactaaagg tgttgttaaa ggagaaaaaa cattaaatca attagcagag atgtttggaa
    19081 tagaaagtga tgaaaagtat gataaatgta taaaggttgc agacaaagtt atcaacgatt
    19141 tgtataaatc aagagatgat aaaatggaat tagtagaaaa aatagcttat gcacctagag
    19201 tgaaaaagtg gaaagagtta ggtataatgc ctggtggtgc aaagtcagaa gtttttgatg
    19261 caatagtaaa atcatcaaca aatttaaata gtgacccagt agacatgcta gttaattgtt
    19321 tgaacttagg tatatcaaca ggattatatg gtcttacact aactaatctt ttaaatgatg
    19381 ttatgttggg agaaccagtt ataagaatgg ctcctgtagg atttaatgta atagacccag
    19441 actacataaa tataatgata acaggccatc aacattcaac atttgcaaat ttccaagata
    19501 gattaaaaga tgaagatgtt ataaaattag ctcaatctgt tggtgcaaaa ggctttaagc
    19561 tagtaggatg tacatgtgtt ggtcaagatt tacaattaag aggagaacat tatcaagaag
    19621 tatttgctgg acatgcaggt aacaatttta caagtgaggc tgttttatca actggagcaa
    19681 tagatatagt tctttcagaa tttaactgta ctataccagg gcttgaacca atagcagata
    19741 aatataaagt aaaaatggtt tgtttagatg atgttgctaa aaaagcgaat gcagaataca
    19801 taggtttaga cagaagtaaa ttagatgaac ttagtaacac tttaatagaa aaagcattgg
    19861 agtcttataa ggagagaaga ggaagtattg aaatagatat accaaaagac catggatttg
    19921 aacaatcttt aactggtgta agtgaaaaga acctgaaagc gtttttagga gattcatgga
    19981 aacctcttat taatttaatt gcagaaggaa aaattaaagg tgttgcagct gttgtaggat
    20041 gttcaaatat gacagcagga ggacatgatg taaatactgt tgaacttact aaagaattga
    20101 ttaaaaaaga tataatagta ctatctgcag gatgttctac tggaggatta gaaaatgttg
    20161 gtcttatgtc acctggagca gaagaattag caggagaaaa cttaaaagaa gtatgtaaga
    20221 ctttaggaat accaccagta ttaaactttg gaccatgtct agctatagga agactagaaa
    20281 tagtagcaac agaattagca gctgaacttg gaattgacct accacaatta ccattagtgc
    20341 tttcagctcc acaatggttg gaagaacaag cattagctga tggagcgttt ggtcttgccc
    20401 ttggcttacc tcttcattta gctttacctc catttataac aggaggaaaa ttggtgacag
    20461 aagtattaac agaaaaatta aaagacttaa caggaggaca tgttatagtg aatccagacc
    20521 ctaaatcttc agctaatcaa ttagaagaaa taataataga tagaagaaaa aatttagggt
    20581 taaaggatgt ggaatgcaat gcatagaatt tttataaata aagatttatg tacaggatgt
    20641 aagagctgtg tactagcatg tatgctaaaa cacaataaag attatgacat gtacactctt
    20701 gatttagaaa atatagataa tgatagtaga gggcatatag aattagatag taaacataat
    20761 aatccagttc caattctttg tagacactgt gatgaacctg aatgtgtatt agcatgtatg
    20821 agtggtgcaa tgcataaaga tagtgaaagt ggaatcgttt catatgatga agagaaatgt
    20881 ggttcatgtt atatgtgtgt aatgtcttgt ccatatggat tattaaagcc agatgataga
    20941 agcaagcaga acatacttaa atgtgattta tgtaaagatg aggagtatcc tagatgtgta
    21001 gctaattgcc caagtggagc aattgaatta cagaaggagg aaaatgatga attatgtagt
    21061 gttaggggct agtgcagctg gtataaatgc agtaaaaaca ttaagagaat tagataaaga
    21121 ttcaaatata gtagtaattt ctaaagatga aaacgtatat tcaagatgta tgttgcatca
    21181 cgttatatct gaacacagaa ttttaaaaca aataaatttt gttgatgaag attttatgga
    21241 gcaaaataat gtaaaatgga ttgcaggtaa gactgttaaa ggtatagaca taaataaaaa
    21301 ggtagttcag acagaagaca ttactgtaaa ttatgataaa cttttaatag ctacaggtgc
    21361 atcttctgct attcctccta taaaaaattt aagagatgga aattttgtat attctgtgag
    21421 aaacatagat gatatttata aaataaaaga aaaagcacaa aattctaaaa atgtagttat
    21481 aataggtgct ggtttagttg gtatagatgc attagtggga ttatttaaat atgagcagtt
    21541 aaatatttct gtagctttta tggaaaagta cattttagat agacaattgg atgaatatac
    21601 agcatcagtg tatgaaaata agttcaaaga aaaaggtgta aaattttacc caagtgcatc
    21661 aatacaagaa attgtattgg ataacagtaa aaatgttaca ggtgttgcat tttcaaatgg
    21721 tgaagtttta gatgcagaca tggtaattgt tgctacaggg gttaaaccaa atgctgactt
    21781 tttagatgga acaggaatag aatatgatag aggtataata atagatgata tgtgccaaac
    21841 aacacaaaaa gacatatatg cagcaggaga tgttgtaggt aaaaatgcta tttggcctct
    21901 ggcagtaaag caaggaattg tagctgccta taatatggtt ggaaaagata agaagataga
    21961 agatgaattt gcttttaaaa acagtatgaa tttcatggat ataccaacta tttctatagg
    22021 aatgaataca cctgtagatg atagctataa agtgctaact agacatggaa ttaatgatta
    22081 taaaaagttt gtttttaaag ataatgtaat ctatggagca gttatacaag gagatatttc
    22141 atatgtaggt gtattaactt atttaataaa aaataaagtt gaaatatatg atttagaaaa
    22201 taggatattt gatatatgtt atgcagactt ttttaatata aaagaaaatg gagaattttg
    22261 ttatagtgta tagtatatac gtggagtaag gtttataaat acagtaaatc aataaataga
    22321 gttattctaa aataagaaaa atgacaaatc ttatttagaa atagctctat tttttgtaat
    22381 taaatttaaa ttatattcaa tttgtaaaat attattttga acaattatac atatactctc
    22441 tagttagagg taaatcattt tttatacctt tagtgaaaag tatttgatgt atatctataa
    22501 taccagtgtt gaaagcagca gcacaagaac aaaggtataa atcccacatt cttataaact
    22561 tatcatcaaa catttcttta atctttggaa gattctcaga gaaatttttt tgccagtata
    22621 gtaaggtttt tacataatgt aatcttagac tttctacgtc tatagtatga tatttgtaat
    22681 cactacaaat atgtatcatt tctcttaggc taggaataac tcctcctggg aaaatatatt
    22741 tttttatcca agggtctcca taagattcct gcaatccact tatatagtga agtaaaaaca
    22801 atccaccatc ttttaaaaca gcatttacgt ttttaatgaa aagttcatag ttttctctac
    22861 caacatgttc aagcatccca acgcttacaa ttctatcaaa cataaggtct gattttttta
    22921 attctctata gtccataagt cttacttcaa gatagtcttg aaggttctct tctttaattc
    22981 ttgcgttaaa ttccttaaat tgctcttcgc taagtgtaat tccaacgccg tgaattttat
    23041 atttttttgc agcttctatt agtaaaaatc cccaaccaca accaatatcg agaaggctca
    23101 taccttcctc taaatttagt ttagttaata tgtggtgaac tttattgact tgagcatcat
    23161 aaagagtatc attatcattt ctaaagtatg cacaagaata actaagtgtc ttatctaacc
    23221 ataagctata aaaatcgttg ccaatgtcat agtgggcatg tatttctttc ttttgatgtc
    23281 tcattgaatt tgatgagtgc aatagatgtt ttacagctga attatcaata ttgaatttgt
    23341 ctatttgttt taaaagtaga tttaaagtta agaataaatc tccctcaact tcaatgtctc
    23401 tatttatgta ggcttctcca agtgctaaag atgtactttt taatagttca gacttgctaa
    23461 tatcattatt tactataact ttgaactgag gggagccctc tccaattaga aattcttcct
    23521 catctttaag cctaactaga aatggtgttt caccaaattt ctctaaatag tcttttaaaa
    23581 aattttttgt aatattcata ttaccagctc cttctaatgt aaatccagta agtttccctg
    23641 cttaaaatat attatagtcc tttttttaaa aaagtaaaat tttttcaata aattttttat
    23701 ttaaaggaaa tttatttttt ataaagaaat ttcatgttgt agtatatttt ttgcttataa
    23761 attttggtac tggatataat attaaactgt taatgatata ataaatttaa tctataaagt
    23821 aaataaaatt ttgtaataaa tagttaaagc tattttataa ggagatatat gatggaagta
    23881 tatgctttgg ttgggtcaag tggcacaggg aagagcttta aggctttaga gttcgcatat
    23941 gaaaatgata tagaatatat aattgatgat gggattttaa tatacaaaaa caaggtttta
    24001 gctgggatat cggcaaaaca agcaaatact actatagaag cagttaaaag ggctattttt
    24061 tataatctgg agcatagaca agaagttaga gaagcaatta aaaaagaaaa tataagaaaa
    24121 attcttatta ttgggacatc aaaaaaaatg gttaatcaaa ttgtagagag attgtcaatt
    24181 ggaagggttt gcaagtttat aaatatacaa gatataagta ctaaatatga aatagaaata
    24241 gcaaaacaag ctagaaaaga aggaaatcat gtaattcctg ttccagcagt tgagataaaa
    24301 agtatggcaa gtggtcttag tataaattct ttgaagagac tttttagaaa aggaagtaat
    24361 aggaatatgg tagttttaga aaaaacaatt ataagaccaa cttttagtta tataggaaag
    24421 ttttatatta gtgctgatgt aattaaacag attattgaat atgaagtata caactttgga
    24481 agcattgata gaataaataa aatcaatata gagaattgca ataattttat gaatattttt
    24541 gtaagtataa atatcaatga tttagaaact ataaaaaaaa ttgaagacat acaacagaca
    24601 ataaaaaagt ctattgagaa aatgacttta gttaatgtac aaaaaataga tattaacatt
    24661 cataaaatta aaaaaataaa cttcctccaa tgttaaaaaa taaactgaga aaatgatata
    24721 ctaatttgca ataaagtgtg ctataattaa actgtaaatt taggaaatgg ttttttctaa
    24781 atggagtata cataattata acgtatttat aagggggctt tcaaatgtca ggaaaagatg
    24841 taaatgtctt cgagatggcg caatctcaag taaaaaatgc atgtgataaa ttaggtatgg
    24901 aaccagcagt ttatgaatta ttaaaagaac ctatgagagt tatagaggtt tcaattccag
    24961 taaaaatgga tgatggttct ataaaaactt ttaaaggatt tagatcacaa cataatgatg
    25021 cagtagggcc aacaaaaggt ggaataagat tccatcaaaa tgtttcaaga gacgaagtaa
    25081 aagctttatc tatatggatg actttcaagt gttctgtaac aggtatacca tatggtggag
    25141 gtaaaggtgg aataatagta gatccatcaa ctttatctca aggtgaatta gaaagattaa
    25201 gtagaggata catagatgga atatataaat taataggtga gaaagttgac gttcctgcac
    25261 cagatgtaaa tactaatggt caaataatgt cttggatggt tgatgagtac aataaattaa
    25321 ctggacaaag ttctataggt gttataactg gtaagccagt tgaatttggt ggttctttag
    25381 gaagaacagc tgctactgga tttggtgttg ctgttactgc aagagaagct gctgctaaat
    25441 taggaataga tatgaaaaaa gctaaaatag ctgttcaagg tataggaaac gttggttctt
    25501 atacagttct taactgtgaa aaacttggtg gtactgttgt agctatggct gaatggtgta
    25561 aatcagaagg ttcttatgct atatacaatg aaaatggttt agatggtcaa gctatgttag
    25621 attatatgaa agaacatggt aacttattaa acttcccagg agctaagaga atatctttag
    25681 aagagttctg ggcttcagat gttgatatag taataccagc tgcattagaa aactctataa
    25741 ctaaagaagt tgctgaatct ataaaagcta aattagtttg tgaggctgct aatggaccaa
    25801 ctactccaga ggctgatgaa gtatttgctg aaagaggaat agttcttact ccagatatat
    25861 taactaatgc tggtggagtt acagtttctt acttcgagtg ggtacaaaac ttatatggat
    25921 actactggtc agaagaagaa gtagagcaaa aagaagaaat agctatggtt aaagcatttg
    25981 aatctatttg gaaaatcaaa gaagagtaca atgttacaat gagagaagct gcttacatgc
    26041 attcaattaa gaaagttgct gaagctatga aattaagagg atggtactaa gatttactct
    26101 taataaataa taggatataa ttatttaaga tataaagggg ctgtacatag tacagccctt
    26161 aaattatgtg gcttacaatg aagtaagcta tttttgtttt aacttataaa aaacttgata
    26221 aattatgtaa tttagaatgt attttttacc accacatgat tacaaattag aagagttaga
    26281 ttagattttt agacatgaac ttatgcattt taaaagcaaa gaccttaatt taaagtatct
    26341 agtattattt ttaaaaatag tatattggtt taatccattt atatatataa tggaaaaata
    26401 tatggatttg gattgtgaac tttattgtga tgagagagtt ttaaaaaatt gtactgtaca
    26461 acaaaagcaa gaatatgctc taactattgt aaattcaatg aaaagaagta caaatttttc
    26521 aaataaattt gtagctggat taaataaaca atctgatatt agaaaaagag taataaacat
    26581 gttcagtgaa aaacataaaa atggtatctt aagggctttg attataagct tgttttcttc
    26641 tattacattt tttaaattcg attcaactag tattattgaa gagaatgatt tcttagagag
    26701 gtcaagatat acgtttgaag gaaggcaaga agacatgttt gtaacaatag attttatata
    26761 tgcagatgta cctataaaac ttagaaaaga gcatgaagaa aactgtagag tcaatggaat
    26821 agtaccaaaa gattcagatt caatagaaat tattcctaga ttttataaag attgtatgga
    26881 tttaaaaaaa taagttagac ttaatattga tgttgatatt atgaattttt tatatttaag
    26941 caattgaaaa ttttattata gattcaattt tatatgtgtt taagtatgaa atttatagat
    27001 agttgaaata attaaatatg attgatgcat aggaatcatt actaagctat aattaattat
    27061 aagggagttt aaataaatta tgagttacac aattataaaa tgataaaaaa tagttatctg
    27121 ttacaaaaaa tgtatctttt taattaataa agataatatg aaaacttaaa aggcaaataa
    27181 acttaaacat aaaatactct taaataagat aggagaaaaa tgtatgtcta actttattct
    27241 aaatgggatt tttagaacag ttatagtaag tagtctaagc attcttatga tattgatttt
    27301 caagaaaaat gtatttaaaa gatttagcaa aaaatttaat tattatatat ggatgatagt
    27361 tgttattaaa ttatttttac catttacata ttatactttt acaataaata tcttgagaag
    27421 taaaaaacac attaatatta ataacataaa tttagaggga tttaataatg tttcaactat
    27481 aagtaataat attatattgt acacttggat tataactgta gtagtttatt taatttacac
    27541 tatatttaaa tatataaaac ttaaaaattt aataaatgac ttatcttatg atgttgatga
    27601 tggagagatt gtaaatcttt ataaaaatat attagaagaa tttaatataa caaaagatat
    27661 aaaactcaaa tactcttatg aagttgaaac accagcattt tttaattcat gtgtgctttt
    27721 gccaccacat gagtataaat tgaaagagtt agactggatt tttagacatg agcttatgca
    27781 ttttaagagt agggaccttt atttaaaata tgtaatcctg tttttaaaaa cagtatattg
    27841 gtttaatcca tttatatata taatggataa acatatagat ttagattgtg aactttattg
    27901 tgatgaaaga gttttaaaaa atcgaaattc agaggaaaaa aaggattatg ctttaacaat
    27961 tctaaatgca atgagaaaag gttcaaatac ttcaaataaa tttatagctg gactccataa
    28021 gcaatctgat attaaaaaga gagttatgaa tatgtttaat gaaaagtaca agaatggtat
    28081 attaatggca ttaactttat gtttattatc ttctattact tttttgaagg ttaattcaac
    28141 gagtattgtt aatcttaata tattgccaaa aggaatggaa gaaaaagatg ttactaatag
    28201 tgcaattgtt acaatgatag aatttacata tgcagaagct cctaaaagta tgagagaaga
    28261 acataaaata aattgtgaat tcttaggttt aatacctaaa gactctgata aaataggtgt
    28321 tggtatagaa tattatgaca gtctattgaa tgattaaata aatattattt taacagatat
    28381 taattataaa gttttgaata gtaatttgtt gagaaataaa tatatcctta taaaaataga
    28441 tacttatata ccaagaataa aaaatagtca agatagtaca caaggatata cttataaaga
    28501 actcaaataa gtgaaataaa ttattaatta taaggtttat aattttaaaa aattagataa
    28561 attcaggtgt aaaatactat aaaacacaat tcggaaaagt gtatgttgaa cttcatttaa
    28621 aatggaattt caaagttgct atagtaagta gtttaagcat tcttcttata ttaatctttg
    28681 agaataatgt atttaaaaaa gttagtaaaa aatttaacta ttgtatatta atgatagttg
    28741 ctattgatat attatctaaa aaaattaagt atgaaaagat tactgctagg acaatctttt
    28801 catacttaat ttttaatatt tatattatcc aaaattttca tctttttaac ttagaatttg
    28861 agaatcacta ttaggaaata ggctttgatt tatgtagggt taaaaatttc acagaatatc
    28921 taactttata ctaaatccat caaaaaatat acgccatata aaagcgcata aaaaaacaca
    28981 taaaacaata tttatgcgca ctttaacctc gaatggtaca aaattcttta cttttacaga
    29041 cccatattat ataattaagt aaataatgta tatttaggtg acatattgga taagctaatt
    29101 tatttatttt attaatataa tgatactata aaagttatat aaagtggttt acaaaaaagt
    29161 tacagataga gcttttatta atgtattgtg tattagtatt ttatccttag gtacacttca
    29221 cctacaaaat agaatcataa gataattatg ggaaaatttt aggaggttta tcgtgaagaa
    29281 aaagatatta ataccagtat ttgcatcagt tatggcatta tcagtaagtt caattgtaaa
    29341 tgcagatgaa gtaaatgatt catctcaaaa taaggatgat aaaacaaata ctgaattaaa
    29401 tttaggtgaa tataaagaag taaaatataa agttgcaaaa ataaaagatg gagtagctat
    29461 aaagataaga gaagaaggtc aagttcaaaa catagcttat tctggagatg aatttacggt
    29521 tttaggaact caaggagaat gggttaaggt taaagttgaa gatggcgaag gttggttagc
    29581 tactagatat gtagatatat ctgaaggtgt aggatatact aacgctgata aagtaaactt
    29641 aagaaaagat aagagtgaaa gttcagaagt aattgaagag ctggaaaaag gaagttcttt
    29701 attggttttg gaagataatg gagattggtt aaaagttaaa gatggggaaa cagaaggata
    29761 tgtaaaatca tcttatatat ctgataaagc tcctgtaata gaagagccac aagtaaaccc
    29821 aagtattgac caaaatgtag attctacaaa taataatcaa caaaacaatg caaatactaa
    29881 tcaacaaaat aataattcaa atgtgccaac agctaactct aatgcagttc aagctgtact
    29941 taacttggca tattctaagc aaggttgtcc atatgtttgg ggagcagaag gaccaaacac
    30001 ttttgactgt tctggattta cacaatatgt gtatagaaat gcagtaggaa agaatatacc
    30061 aagaacatct aaagcacaat ctaaatatgg acaaactgta agtaaagcaa atttacaacc
    30121 aggagactta gtattcttca caactaatgg ttctggttct gttagtcatg ttggaatata
    30181 tgtaggtggg ggtaatatga tacattcacc atcaacagga aaaacagtta gtgtaactag
    30241 tataaattca tcatactata cagcaagatt tgttacagca aaaagaatat tataatcggt
    30301 ttgtaatatg acaaattgat aaatacataa atatatataa acgctctata ttatatttaa
    30361 tttaatcatg gaaacaaaaa atgattatat tttaaatgta ctatagagcg tttttgtatc
    30421 actttaaatc taatcaagat tcaagttaat atgactgtta aataggagcc ttttcatatg
    30481 atgattattt gcgcaatccc ttgacaggat agggcaaagg tggtaagcta ctaacagtac
    30541 aaaaatactt ttaattttag ttcagagagg ctaaaaaagg aggacgaaag atgttaaaat
    30601 caagaaattt aatccagcca gaagactttt caatagaaga aatagatgaa atattagaat
    30661 tagctcaaaa aataattgac aatccgtcaa aatattctcg tatatgtgaa ggaaaactat
    30721 tagctacatt attttatgaa ccatcaacaa gaacaagatt aagctttgaa tctgctatga
    30781 acagattagg aggacgtgta gtaggctttt cagagccaaa ttcatcctct gcatcaaaag
    30841 gtgaaactct aggagataca atgaggatag tatctggtta tgttgatata atagctatga
    30901 gacatcctca atcaggtgca gcttcagaag cagctagata tacggaagtg ccatttataa
    30961 atgcaggaga cggcaaaaac cagcatccaa ctcaaacact tacagactta cttactataa
    31021 aatcattaaa aggaacttta gaaagccata caataggatt atgtggtgat ttaaaatatg
    31081 gaagaactgt gcattctttg gttaaggcta tggcaagata taaaaataca aagtttgtat
    31141 ttatagcgcc tgaagagtta aaaatgccag attatataaa agaagctata aagggacatg
    31201 catattatga aactaataat ttggatgatg ttataggaag cttggatgtt ttatatatga
    31261 ctagagttca acaagaaaga tttgaagata aatcagagta tgaaagactt aaaaactatt
    31321 atattttaaa taaagctaaa ttagaaaagg catctaaaga tatgttagta atgcatccat
    31381 taccaagagt aaatgaaata gacatagatg tagatagtga tgatagagct gtatatttta
    31441 aacaagctaa atatggaatg tatgttagaa tggctttaat aataaaactt ttaggtataa
    31501 atgaagacta atagttatca tataatagta aaacaaagga gattttggga tgtataaaat
    31561 tctggaaaat atatatatag gcgaagatat gtatagaatg aaagtaaaag gtaattttga
    31621 aggtaaaatg ggacaattct atatgttaag agcatgggat acttatccag tactttcaag
    31681 acctataagt atacatgata tagatgaaga agggataact tttctttata aagtagtagg
    31741 agaaggaact caaattttga gtaacctaaa ggtaaatgat aatataaaat tagaaggccc
    31801 ttatggtaat ggatatgcta aggttgatgg aaaggtagct ctagtaggag gaggaatcgg
    31861 tgtagctcca ctatatttgg ttgctaaaaa tataaaaaat tgtgatgcat atcttgggtt
    31921 tagagaagat gttatattag aagatgaata taaacaagta tgtaataaag tctatacaac
    31981 agtaggaaat acttttgtaa cagatataat tgatgttgag aaatatgatt atatattaac
    32041 atgtggtcca actccaatga tggaaaaatt agttaagatg gtagaaggta ctaaaacgag
    32101 aattatggta tctcttgaaa accatatggc ttgtggagta ggtgcctgtt tagtatgtac
    32161 gtgtaaaact aatggaggaa ataaaaagac ttgtaaagat ggtccagtgt tctggggaga
    32221 ggacgtgatt tttaatgggt aatttaagtg tgaaatttgg aagtgtagaa tttaaaaatc
    32281 cagtaataat ggcgtctgga acttttggat ttggaaaaga atataatgag atttatgata
    32341 tacaaaaact tggtggtata agtagcaagg gtcttacttt aaataaaaaa cctggtaaca
    32401 atggtatgag agttcatgag acatcatccg gtatgatgaa tagtgttggg cttgaaaacc
    32461 ctggagttca aggatttata gactatgaat tacctttttt tagtaaacta gacttagtca
    32521 gaatagctaa tgttggaggt gggacattag aagactactt attaggggtt caaatgttaa
    32581 atgacaagcc tatagacatt attgaattaa atatatcttg cccaaatgtc aaagctggtg
    32641 gaatggcttt tggtataaaa aatgaagtgg caagagaagt tgttcgtgag gtaagaaaca
    32701 taacgaaact gcctttagta ataaaattat cacccaatgc agaagatatt gtaggaatgg
    32761 caaaagtttg tgaagaagaa ggtgctgatg gagtttcatt agttaatact tttaaagcaa
    32821 tggcaattga tataaaaaat agaagaccag tatttgaaaa tgtatatgct gggttatctg
    32881 gaccagctat aaaacctata gctttgagaa tggtacatga agtgtgtaaa aatgtaaata
    32941 tacctgtaat gggaatgggc ggaataacta aagccacaga tgctatagag tttataatgg
    33001 caggagctac ttgtatccaa gttggaactg caaattttat gaatcctaga ataggtattg
    33061 aaataataga tggaattaat gaatttatgg atagagaagg aataaaaagt ttagacgaaa
    33121 taagaggaat tatataaggt agaataaata gtattttaaa gataaaaaat atagattaaa
    33181 taaacaataa ttttataaca ttaacatgga ggaaaaataa tatgagtaaa gtagatgtag
    33241 tggatatatt aaagaaaagt gatgcattgt tggagggaca ttttttatta tcttcaggaa
    33301 aacacagtaa tagatacgta caatgtgcaa aagtattaag atttccagaa tatgctgctg
    33361 aggtattaag tacagttgtt gaacaaataa aagacttaga tatagactta gtagtaggac
    33421 cagctatggg tggagtaata gtttcttatg agttaggaag acaattagga aaagaagctg
    33481 tatttactga gagaaaagac aatacaatgg agttaagaag aggatttgaa gttaaaaaag
    33541 gagcaaagat aataattgct gaagacgttg taactactgg taaatcaact atggagacaa
    33601 aaagagtatt agaagcctta ggtggagaag ttgtaggtgt tgcatgtata gcagatagaa
    33661 ctaatcatga tataggtatg cctatatata gtgctataaa acttgatatt caagtttatg
    33721 aatctgatga gtgtccttta tgtaaggaag gaaaattacc agttgttaag cctggaagta
    33781 gagagttcaa ggaattaggg atgtaataaa aacttaatta tttatagtgt tacttaaaaa
    33841 atgtaaattt tttagagtaa aaatttgtaa tataacatat aacttaaaaa taaaaagcag
    33901 ttagccttat aaatgaaggt tagctgtttt tttgttaaaa atatatttac aaaataagag
    33961 atagtagcag tacaatataa gtataaggta aaagtattat atattaggga ggggtaagta
    34021 tgaaaaatca attaaatgaa aatcataaaa aggttgtatt ttttggagta ggtgctgtag
    34081 gagctacttt tgcagaacaa ttttttaact ctaaatatga ttttaaaatt ctttgtgata
    34141 atgaaagaaa gaaaagatat ttagaagaag gatttataat aaatggaaaa aggtatgatt
    34201 ttgattatgt aactaaagat gagtataaac aagaggctga ttttataatt ataggtctaa
    34261 aatataataa tttaaaagaa aatataaaag aattagatgg attagttgga aaaaatacag
    34321 ttataatgtc tctgctaaat ggagttgata gcgaagagat aataggagaa agatttggaa
    34381 ttgaaaaaat ggtatattca tatgttacca atatagatgc aaagaaaatc aataataata
    34441 ttatacacac tactaatggg ataattgtat ttggtaacaa agataatagt gaagatagaa
    34501 aaactaatat aataaccgaa gtctttgatg atgtaaatat agaatatact ttatcaaaag
    34561 atattcaacg agatatgtgg tggaagtaca tggttaatat tggtgtaaat caaacttcag
    34621 ctatacttgg tgcaccttat ggagtttttc agagttctga gcatttaaga gaattagcaa
    34681 aatctgcaat gagggaagtt gttgctatag cacaagcaaa agacatatct cttacagaag
    34741 atgatgtgga acattcatta catagaatac tagaacattc aaaagaagga agaacatcaa
    34801 tgcttcaaga tgtggaagct catagactta cagaagtaga tatgttttct aagaatatct
    34861 gcaaacttgg aaaaaaatat aacataccta ctcctataaa tcagactttc ttttatatga
    34921 taaaagtaat tgaaagtaga ttttaaaggg tctttgtaag aaatattgat aattattgat
    34981 tttaaatttt attaatgtta tatactattt aagttactaa atatttttaa ctcttcaatg
    35041 aaaatagttg ctgcttttga taaagttata tcttttggaa atatatatga gaaatgtctg
    35101 ttgtagctgc ttccaagctc tatgacagac agctcattgt ttagaacagg taagcttgtc
    35161 actagattag agactattgt aattcctaaa ttatttctaa cagattcttt gacagcataa
    35221 ttacttccaa aaaccatcat actttttgga ataatttctt taacacttaa aaacatatct
    35281 aaataatctc tggttccaga accatcctcc ctgactatcc atttttggtt ttgaagttta
    35341 tcaaaactaa aatcttttaa taaatgactc ttgtatggaa gtgctaaaac catcttatct
    35401 tcaaaaaaat attcttgaat aaatgaaggg gaagagcaag tgccttcaat aagaccaatg
    35461 tctaaaatat aatccttaac atgagaagat acgattgatg tattttttat aaaaacttct
    35521 acatctatgt caggatactt tttagaaaat aatgctagaa aatttggtaa aatatactct
    35581 ccaatagtta aacttgcacc aatctttaag tgaccagtta tagcatctga aacttggctt
    35641 acatcatgat aagtaatatt taaaagattt aatatttctt tagctctttt gtacaagatt
    35701 tgtccacttt ctgttataaa aatggttttt tgtttaatag acctgtttat aagcacaact
    35761 ttaaaataat tttctagatt ttttatgtgt ttacttacac ttggttgtga tagatttaaa
    35821 tattccccag ctttagtaaa gtttttgtat tcaacaacag ctacaaatgt ttttaattct
    35881 tcaaacaatt ttttgtctcc tttacctaat gaaattttac attttttata tactttctac
    35941 agataattat actatatata ataaccatta aaaacattaa tcattacgat attatatatt
    36001 tattttactt atggttatta caattatata ctattgctat gaagaaaact atattaatta
    36061 taaggtaggt atattatgtt aaagaaaaaa agcagtttga cattaaaaac tataagggaa
    36121 atattaccag gactgtttgt atcagtatta gtaggttata ttagtatatt tatttctatt
    36181 ttaattccta aggtaggggc agcatcaatt tctatatttt taggtatgtt tgtaggaaac
    36241 ctatttttaa atcaaaaggt atttcaaaaa ggttataaat tttcagagac agatttgtta
    36301 tcatattcaa tagtactatt aggagcaaca ctcagtgtat ctaccttaat agacttaaaa
    36361 gtttcaggaa ttttatttat aatattgcaa atgacaataa caataatagc tgcactttat
    36421 ataggtaaaa aactaggatt tgaagaaaac tttagatttc taatggcaag tggaaatgca
    36481 gtatgtggtt cttctgcaat aggagcaaca gttccagtgg ttaatgcgac agataaagaa
    36541 aagggaattg cagtaactat tgtaaatgtt actggtatat ttcttatgtt tttacttcca
    36601 ataatatctc aatttttata tagccatgaa cttgtaaaaa cttcagcaat gataggtgga
    36661 actttgcaat caattggtca ggttgtagca agtggagcaa ttgttggaga aaatgtaaaa
    36721 gatttggcta ctatttttaa gatagtaaga gtaatatttc tagttgttgt tgtattagta
    36781 tttggacata tgaaaaatca atctaatagg gaaattcttg aagaagaaaa ggatgagata
    36841 aaaaagaaaa aagtgactat accatggtat gtaattggat tctttataac ttgtgcactt
    36901 ttttcaatga acattatacc aaaagaagta tctgtgttgt gcaaagaaat aagtaacaaa
    36961 ctagaaataa tagctttagc agcaattgga ttaaaggtta atgtaaaaga tttagtgaaa
    37021 caagggaaag aagtttcttt atatggttta tttgtaggta tagtacaagt tgtatcagct
    37081 gtagttttaa taaaaatatt tatatagcat aaaaatagta tttgtaatat taatttgatt
    37141 aactaaaata atatgatact aataatttat aatataaata aaaaatgaat ttcgataagt
    37201 ttaagtgggt ataaacttat agaaattcat tttttattta aggtaaaaat ttaaagtaaa
    37261 atattatttt acataataat aaccttataa attttgaaat tacttatctt tgtgttaaaa
    37321 taagtaaaat gcacatatta gagctaagtt tttaagtaaa taaacaaaat gaaaatataa
    37381 atattaagga gatttggtat atgaatgttt atgaaaaagg taatggagtt atactagaag
    37441 gagtaacaga ttttgaccca gtacatatat ttgagtgtgg tcaatgtttt agatggcaca
    37501 aacaagaaga tggctcatac actggagttg caaagggaag aatattaaat gtcaaaaaag
    37561 agaatgataa aatatattta aataatacta atttaaagga gtttaacagc atttggtata
    37621 attactttga tttaggaact gattatacag aaataaagaa taagctaaaa aatatggatg
    37681 aatatttaaa taaggctact gaatttggat ggggaataag aatattaaga caagatggat
    37741 gggaaatgct tatatcattt ataatttcct ctaataatag gattcctatg atacaaagag
    37801 cgatagaaaa tttatcaaga aagtttggta agtatatagg tgaatatgaa ggtaatgaat
    37861 actatgcatt cccaacacca gaagaactaa ataaggcctc acaagaggaa ataagagcat
    37921 gtcaaacagg ttttagagat aagtacataa aaagtactac acaggcagtt atagagaata
    37981 atgatgaggt atctgaatat acaaatttaa gtacagagga ttgtagaaaa gagcttttaa
    38041 aatttaatgg agtaggacca aaagtatgtg attgtattgc attatttggt atgcaaaaat
    38101 atgattcttt tccagttgat gtttgggtta agagagttat gcaagaattt tatatagatg
    38161 aagacatgag tttacctaaa atgagaactt atggaatcga taaatttaaa gaaatgtctg
    38221 gatttgctca acagtactta ttttactatg caagagaact cggtatagga aaataaatta
    38281 agggggagaa attatgggag taataggaac aatatttctg ttctatttaa ttatatcata
    38341 tctagctgga gccataattt ctgtgattat attgcttgaa aatagagacc ctgcaaaaac
    38401 aatgtcttgg ctattgatgt ttattatatt tccaggtgta ggtttaatga tatatgctat
    38461 ttcaggtaga aatattagaa aaagaaaatt atttaagact caaaaactag ctaataatat
    38521 aaaagaaaag aaactatttg atacattaga aaagataaca gaaatagttg aattagaaaa
    38581 agaatctata aaacaaaata agcttttaag agatgaagag gatggtagtt atagaaaaag
    38641 ggtaataaat atgttgttaa agactggtat gtttcccttt actaaaaata ataaagtgga
    38701 tgtatttgta gatggaaatg aaaagtttaa aagacttata gaagatataa gagaagctaa
    38761 agaccatatt catttagagt actttatcat caaagatagt gaaataggta gggtgttaaa
    38821 agaagaactt ataaaaaagg ctaaagaagg cattaagata agaattttat atgatgatgt
    38881 aggatgctgg agattttggt ttaatagaaa attttttcga gaaatgaggg aagtaggtat
    38941 agaaattgca gcatttttac ctacaaaatt tcctataata ggagggaaat taaactatag
    39001 aaatcacaga aaaattgttg ttattgatgg aataattgga tatacaggtg gaataaatat
    39061 aggagatgaa tatttaggca aaaatgataa gtttggatat tggagagata ctcatattag
    39121 aattaagggt atttctgtat acatgcttca aatgacattt ctgattgatt ggtattatac
    39181 gacaaaagaa gtattagtga ctaaaaatta tttcccaagt gtagggaatg ttggtgaaag
    39241 tatgatacaa gttgttgcga gtggtccaga cagtgactgg gaagatattc attatgctta
    39301 tttttctgca atatgtcagg ctagaaaaaa tgtttatata gaaactccat attttattcc
    39361 agatgaaagt ctactaaaag ctataaagag tgctgctctt agtggagttg atgtgagaat
    39421 aatatttcct aaaattgcag accacaagat agtaaatata gcatcttatt catattttga
    39481 agaaatatta agagcaggtg gtaaagttta tttatataat aaaggattta tacattctaa
    39541 agtcgtaata atagatgata aaattgcttc tgcaggtaca gctaatatgg atttaagaag
    39601 ttttatgctt aactttgagg taaatgcatt tatctatgat gaagaagtta ttagggtaat
    39661 gacagatgat ttctttgagg atttaagtca ctgtgaagaa cttaatttgg aggtatttaa
    39721 gaatagaaat atcatacaaa aaatcaaaga atctgtagca agattatttt caccaatatt
    39781 ataaaaaatt attaaaaaag gtattgaaaa ttatgtgtga ttggtatatt ataataattg
    39841 ttagcactct attagataga gtgataataa ataaaaagta tatatataaa tctacatata
    39901 taagtagtat taatttaaaa ataactaaaa acataggcga actagtctat acttaatatt
    39961 ttaggaggcg tgaataatga aaataagacc attagctgac agagtagtaa ttaaaaaagt
    40021 agaagcagaa gaaaaaactg caagtggaat agttttacca ggagcagcta aagagcaacc
    40081 tcaaatagct gaagttgtag aagttggacc aggtggaata gttgaaggga aagaaataaa
    40141 aatggaattg acagtaggag ataaggttat attccaaaaa tattctggaa cagaagttaa
    40201 gatagaagga caagaataca caatactaag acagagtgat gtattagctg ttattgaata
    40261 aatatagaat aaatttatta ggaggggttt aaaatggcta aagaaattaa attttcagag
    40321 gaaacaagaa gagctttaga agctggtgta aataaattag cagatacagt aaaagtaaca
    40381 ttaggaccta aaggaagaaa tgttatatta gataaaaaat ttggttctcc acttataact
    40441 aatgatggag taactatagc aaaagagata gaactagaag atagatttga aaatatgggt
    40501 gctcaattag ttaaagaagt agcaactaaa actaatgatg tagctggaga tggtactaca
    40561 actgctacag ttttagcaca agctataata agagaaggtt taaagaatgt aacagcaggg
    40621 gctaacccaa tacttttaag aaaaggaata caaaaagcag taacagtagc agtagaagaa
    40681 ttaaaaaatc aatcaagaat agtagaaaca caagaggcta tatctcaagt tgcttctata
    40741 tctgctggtg atgaagaagt tggaaaatta atagcagaag ctatggaaat agtaggtaaa
    40801 gatggagtta taactgttga agagtctcaa actatgaata ctgaattaga tgctgttgaa
    40861 ggtatgcagt ttgatagagg atttgtttct gcatatatgg ttacagatgt agataaaatg
    40921 gaagcagttt taaacgaccc atatatatta attactgata aaaaaatatc taacatacaa
    40981 gaattattac cagttcttga acaaatagtt caacaaggta aaaagttatt gataatagct
    41041 gaagatgtag aaggtgaagc attatctaca ttagtagtaa ataaattaag aggaacattt
    41101 gatgtagtag cagttaaagc tccaggcttt ggagatagaa gaaaagaaat gcttcaagat
    41161 atagcaatac ttacaggtgc tcaagtaata tcagaagaat taggttatga tttaaaagaa
    41221 gctgatttat ctatgctagg tagagcttca tctgttaagg taactaaaga aagtactaca
    41281 atagtagatg gttctggaga taaaaaagct atagaagata gagtaactca aattaaacat
    41341 caagtagagc aaactacttc agattttgat agagagaaat taatggaaag attagctaaa
    41401 cttgctggag gagtagctgt tgtaaaagtt ggagctgcta cagaagtaga gttaaaagaa
    41461 agaaagttaa gaatagaaga tgctcttaat gcaactagag cagctgtaga agaaggaata
    41521 gtagctggtg gaggaactgc ttttgttagt gttataccag caataggaac actaattgag
    41581 agtttagaag gagaagttaa actaggtgct caaatagtta aaaaagcgtt agaagagcca
    41641 ttaagacaaa tagctataaa tgctggtctt gaaggtgctg taattgtgca aaatgttgtt
    41701 aattctgaag cagaaactgg atttgacgca ttgaatgaaa aatatgtaaa tatgatagaa
    41761 gctggtatag ttgacccaac taaagttagt agaagtgctt tacaaaatgc tgcatcaata
    41821 gcaagtactt tcttaactac tgaatctgct gttgctgacc ttcctgaaaa agaagatgca
    41881 ggaatgccag gaatgggtgg cggaatgcct ggtatgatgt aatttaaaaa atttaaaata
    41941 taaattttaa tataaagaac tatttcgact tagattttaa actctaagtt gaaatagttc
    42001 ttttgtatat atctaatttt tgtatatcta taaattcaat acacatattt agataatcag
    42061 tatctagttt gtaataatat tttagagtag tattgttatt ttttaggtta tgattttaga
    42121 tatatattaa ttaaggtata attgttgata gagaataaat caaatttaaa aggatgcgat
    42181 aatatggact taagaaaatt gcttgaagaa gttaaaaatg aaaatattga tatagatttt
    42241 gcgttagaaa agttaaaaga tttaccttat gaagaccttg gatatgcaaa tatagaccat
    42301 catagagaat taagaaatgg gtatccggaa gttatttatt gtgaaggtaa gagtgatgag
    42361 catattttag ggattattga taaaatgaat caaaaaagtt ctaacatatt ggggacaagg
    42421 tgcagaaaag aaacttttct gaaaattaaa gaaatctata atcatgctga gtacgaagag
    42481 gcgtctaaaa ttcttaagat tcaaaatcat gatatagaga atataggaaa aggtaaaatt
    42541 gtgattgcta cagggggaac ttctgatata ccagtagcag acgaagctta tcatacagct
    42601 aagtttttag gtaatgatgt tgatagaata tatgatgttg gagtggcagg tatacatagg
    42661 cttttaaata aaagacataa aatagatagt gctagagtaa tagtagccgt tgcaggtatg
    42721 gaaggtgctc ttgcaagtgt aattggtgga ctggttgatg ttccagtaat agctgttcca
    42781 acttctgttg gatatggagc aaattttgga ggattagcag cattgctagc tatgttaaat
    42841 agctgtgcat ctggaatatc tgttgtaaat attgataatg gatttggagc aggatattta
    42901 gcatcaatga taaataaact gtaaatacat tgatataaat taaacaaaac tatataataa
    42961 aatttaattt ctattatatt tttactatta aaattgagga gacatatatg agtgaaaaaa
    43021 tactttattt tgatataata agcggtatat caggggatat gacccttgca agtttattaa
    43081 atttaggtgt gcctaaggaa atttttttgg aggaaattca taaactaaga atgagcgatg
    43141 aatttaatat aaacatcagc tcgaaaactg aaaatggaat agtaggtaca aaagtagaag
    43201 taattacaaa agaaaaacat acacatagaa atttagtgga tatatttgag gttatagata
    43261 aaagcactct aaacgaaaat gtaaaatcta aagcaaaaaa aatatttatg gtaattggag
    43321 aagcagaagc aaaagttcat ggaactacaa tagacaagat acattttcat gaggtagggg
    43381 ctatagattc aattgtagat atagtaggag cttctatatt agttgactta ctttgtgtag
    43441 ataaagtttg tgctagtaca gtgtctgttg gttcaggatt tgtaaaatgt gaacatggaa
    43501 ttatacctat acctgcacct gcaactatag aaattttaaa aggtgtgcca attaaattaa
    43561 ataatgtaaa tggagaatgt acaactccaa caggagctgc aatcataaaa gttttgtgtg
    43621 atgagtttgt agatgagctt gaattttctc caaagcaaat tggatatggt ataggtcata
    43681 agaagtttga agtaccaaat atactcagaa ctgtattagg tgaaaaaaaa aagaagaatt
    43741 aatttatgaa attagtgcaa acattgatga tatgtcttca gaaatctatt cttatttgta
    43801 tgaaaaaata ttagatgaga aagcattgga tatttataca gagagcattt atatgaagaa
    43861 gaatagacca gcaacaaaag tatcaatttt atgtagtgaa tcagatttag aaaaatttat
    43921 taaaatatta cttttagaaa ctagtacttt tggagtgaga tataatgcat ataatagaga
    43981 aattctagag agaaaatttg taaaattaga tacaaaatat ggagtggtta cagtaaaact
    44041 agggtattat aaaggaaaac tagtcaaggc tactccagaa tataatgaat gtaaaactat
    44101 agcaaaaaat gaagatattc ctataaaaaa agtgtttgct gatataaatt ttagaataaa
    44161 agaagaattt agtgaaaact tattgacata agtaataaat tttgataaat taatattcag
    44221 ccttattaaa taaaagtaaa cagaaaaaaa tatataaaat ataaactcac tcgtatatgc
    44281 tcagaaatat ggtctgagag tctctaccaa gataccgtaa atatcttgac tatgagtgaa
    44341 attattatac caaaagacct agttaagtaa atgtgtaggc tgagttaaac tccctatgtg
    44401 ttggctataa gataaaggta ttttggaagc ctgtatagta atttcacttt tgctagaaat
    44461 tatggaagtt actatacagg ttttttgtgt aaaaagattt aatataattt agactgtatt
    44521 gtgttaaaat aaatatataa aaactatatt atacaaggag agatgtgaat ttatgaaaca
    44581 tgaattagta cttgtaatag attttggagg acaatataat cagttgatag ctagaagagt
    44641 tagagaaaac aacgtatatt gtgaaatact tccatgtact gcaagcatag aaagaataaa
    44701 agaaaaaaat cctaaaggga taatatttac aggcggtcca aatagtgcgt atttagaaga
    44761 ttctccaaca atatcaaaag aaatatttga attaggagta ccaatacttg gaatatgcta
    44821 tggtattcaa ataatgtctc atgtattggg tggagttgta agaaaaggta ataaacaaga
    44881 aaaagaatat ggaaaaacag ctataactta tggaaaatca tcattatttg aaggaataac
    44941 tacaaatagt gtatggatga gtcatacaga tttaatagaa aaagttccag aaggatttac
    45001 tatagttgca aatactaatg attgtccagt agcagctatg gaaaatgtag aacgaaacct
    45061 atatggagtt caattccatc cagaggtgga acactgtttg gaaggggata agatacttac
    45121 aaacttctta tataatattt gtaaagtaaa aggtgactgg actacagatt cattcataga
    45181 agataaaata aaagaattaa aagaaaaaat aggcgataaa aaagctttat gtgctttaag
    45241 tggaggagtt gattcttctg ttgctgcagt tcttattcat aaagcaattg gggacaactt
    45301 aacttgtata tttgttgacc atggtttact tagaaaaaat gaaggaaatg atgtagaaag
    45361 aatatttaga gagaaatttg atataaattt aataagagtt aatgcagaag atagattctt
    45421 atctaaatta aaaggagttt ctgaaccaga agctaagaga aaaataatag gtgaagaatt
    45481 tataagagta tttgaagaag aatcaaataa attaggaaaa atggatttct tagtacaagg
    45541 aacaatctat ccagatgtta tagaaagtgg acatggaaat gctgctacta taaagtctca
    45601 tcataatgtt ggtggaatcc cagaagatgt agacttccaa gaaattgtag aaccattaag
    45661 agagttattt aaggatgaag ttagaaaaat aggattagag cttggtatag aagaaggatt
    45721 aatatttaga catcctttcc caggaccagg tctaggaata agagttatag gtgatgtaac
    45781 taaagaaaaa tgtgatatat taagagaagc tgatgctgtt tatatggacg agcttagaaa
    45841 agcaggttta tacagagaaa tatggcaagc ttttgcaaca ttaccagatg ttaagactgt
    45901 tggagttatg ggtgatgaaa gaacatatgc ttatttagtt ggtttaagag cagttacttc
    45961 ttctgatgga atgacttctg actggtataa gatgccttat gatgtattag aaagaatttc
    46021 taatagaata ataaatgaag ttgatggagt aaatagagta gtttatgata taacttctaa
    46081 acctcctgga actattgaat gggaataaaa tatagaatgc caaaaatcca cataaataca
    46141 ggatttaagg tctctcttac ttctatgtta tactggtttg atactatcaa tatttgccag
    46201 tatcttatgg attaataagt aaaaaacatc ctgctgaatg ataaattcag cggggtgttt
    46261 ttattttgtt ttagaactcc tttgctctga aactcgaagt atttaacact gatgattttg
    46321 ttatctttta gttccttttg tgtcatgctc tgaaagacaa attgatacaa taaaaaagta
    46381 atttcttaat cattgatgga gatatgtatt tatgttactc ttgatggtaa tttgagtaat
    46441 attgttcata gctttttata ttcaattaat tagaaaacca tttggtataa tcataaataa
    46501 acttgatgat ataatagaaa agatttataa ttattagaag tatataaaag tattttatgt
    46561 ctatgaaatg tatgtctata aaacatatag atgacttttg tatattaatg tatgaatatt
    46621 gatattatag aagaattgag ttgtcaatga tactaaatca aatatttata gaagctggag
    46681 ggattatgag aaataaaata attataggaa ttactttttt acttgtatta ctaatgtctg
    46741 gatgtgcttc aaaacaaacc gcagaaataa acgtattagc aactactgat ttacatggag
    46801 ttatacctta tgagttaact tcttatgtaa aagaagaaag aaaaaaagat aaaaatctaa
    46861 ctttagtaga tgcaggagat ttttttgata gtggagaagt gtttggttct agcatggata
    46921 gttattttag tgctagatat aaagatggtg ataataacac tgaaagttat attgagacgc
    46981 ctatttcaaa agatatgaaa gaggtaggtt atgatgttgc agttcttggg aatcatgaat
    47041 ttatatccaa caataaattt tatctagata atatgatatc tgattttgag aagcaaaaaa
    47101 taaatatttt atcggcaaat acgtataaaa aaaatggaga cagttataca aaaccataca
    47161 taataaaaaa tattaataca cctgaaggaa acgtaaaact aggaatttta gggcttacta
    47221 taaaagaagt tggtgagagg aaacagtgga aagatggaaa acttgttgac tctaagtctt
    47281 tagaactaaa agaccaagag ggctacaatg gtgaattgta tatgaatgat ttagtagaag
    47341 atgctaaaaa gtgggttagt ataatggaaa aagagaagcc tgacattata gttgctgtgg
    47401 cacatacagg tgagaaacct aagaaaccta aaaacccagg aaatagaata caagacttag
    47461 ctcaacaagt tgatggaatt gatgctatag ttgcaggtca taatcatgtt caaattgagc
    47521 aacatgatta taaaaataaa tcaggagaaa atgttatagt tactgagcca ggaaagcatg
    47581 gggaatgtat ttctaagatt aattttaaat tagaaaaaaa caatgataaa tggaatatag
    47641 ttgacaaatc tagtaaatta attaaatttg aaaaaaatca agaaagtgat aaatttggag
    47701 aatttatttc ttcaattaat aaagtaagta aagataagaa agaaataaga ttatcagaag
    47761 taaagactcc tgaatgggat aaaatatatg tttttaaatc tggaacatct gcagatgata
    47821 tatataaaac aataggatat aaatggagaa atatatcatc tccaaagagt gatggcatgg
    47881 tgcagattgt tgtaatgaat aataataagc ctgttagcta tatatatggt gaagctgaag
    47941 ttatgccaat taatataaaa tgtgatgaat cagagtataa agataatgtt gtaactattt
    48001 atcctaataa aaatgataaa tttaaaattg aaaaaggtaa acaagaatat agtattaatt
    48061 taaaacatat acaatagaaa cttttatctt atttaagttt agattgtact taaaataaag
    48121 tgtgtattat tttaaaaatt gatgataatt aaaatcacaa cattaaggaa tagtacacac
    48181 tttttatgct aaaaaataga atgttaaaaa attaaacctt taaattaaag tacattgctt
    48241 atattatcca atattatctt caaaggttgt gtaatatttt tatccttatg taatattgct
    48301 aacattttat tttccatatc tatcccatct aattcaatca atcgcaattt tttatgtaag
    48361 agtgaatcta ataataaatt ttctggcaaa atggttatac ctaaccctgc ttgtgcagct
    48421 ttaataagtg caaaagaatt aacactttcc caaacaggat aagctttttg gtttgaaaga
    48481 gataatacac tgtccaaagt atcgcgaatg gcacttcctt gctcacgtaa caataacgga
    48541 aacgtgcata actgtcgtag agataaggct tgtttagtat tggtggtggt tatgcaatca
    48601 tacctttaat ccaagagaaa gtagtaaatc aaactggatg gataagtgag aaaatattta
    48661 cagatattat aactatttca caaatgacac cagggccact ggctgttaat acttctactt
    48721 ttgttggact tcaaattgga gggttttggg gagcagttgc agccacttta ggttgtgtat
    48781 tatgtggtgt agtaatatct ctatttttat ataatttttt tcaaaagcat cagaactcta
    48841 cttatatatt tgaaatatta aatggtctaa aatcagcttc attaggttta attatctcag
    48901 ctgcggctac aattataatt cttgcattat ttgggacgaa taaagtgtac ttcaattcta
    48961 tatttgagat gctaaactgg actgcactaa taatcttttt tgttacacta ctgatagtac
    49021 gtaagtggaa aattaatcct attgtgatta taataatgag tggtatactg ggaatatttt
    49081 tttatttata agtttttgct aagtaaagga tatctatttt tttatatctt aaatccaaat
    49141 agccaataaa gtaaggctat ttggattttt aataaattct gaaaagataa tcagaaacct
    49201 atataacatt taaattatat cactggtttt ctacaaacca atcataagct tcttggcaaa
    49261 atttcttact atctatatag taactattat gaacattatt aatttcaaca agtttctttt
    49321 tacattttag tgaattataa tagctatcaa aatattgggt tttaaaatat ctatcatgaa
    49381 gtgttttaaa gacaagagta ggtatgttga ctccatcttt tatcttacta tcttttgcaa
    49441 taaagcattc taacattgta ttaattatct ttgtactatt tttccaaata tgaggatttt
    49501 tcttttcaaa tattttataa aattcattat catagacttc attataacct ttatatttag
    49561 gtggttttac tgttatgtga aaattaggaa gaaacttaaa gaaaaaatat aataattttt
    49621 atgttctgtt ttatatatta ttcatatttt atcacagata atatactaaa gttaattttt
    49681 ttattgtaca actattataa taattcttct ataatataag acattctata attttatatt
    49741 taagttcatg tgtatttaat tgtttttata taaaatgtcc agtaatacta tttggattta
    49801 tttttatttc atcaggagtt ccagaagcaa caatttcccc tccatttatt ccactgtctg
    49861 gacctatatc gataatccaa tcagaagcac gtataacctc tgtattgtgt tcaataatta
    49921 aaagtgaatg ctgttcattt acaagttttc taaaagtaat taacaaattt tctatatctt
    49981 taaaatgaag tccagtagta ggctcatcca atatgtacag cattcgtttt ttagtttttg
    50041 tccctaattc ttttgctaat tttatccttt gagattctcc tccacttaat cctaatgtat
    50101 tttgtccaag ctttagatat ccaagtccca cttcatctaa taaggagagt tttctatata
    50161 tatcagagca atcgctaaaa aatgtttttg cttctgctac ttccatgtca agtatatctg
    50221 caattgtctt tcccttgtat tgtatagaca gtatttcttt ttgatatctc ttaccttgac
    50281 attcactaca agttacccat tggtctgcca tatattgcag aataattttt gttttaccta
    50341 atccttgaca gtttgggcat tgcccctttt tgctattaaa gctaaaatag ctttcatcca
    50401 ataatttttg ttttgcttgt ggagtttcag caaatagaga acgaatttca tcaaaaatat
    50461 tgatatatgt agcaggtgta gaacggctag attttccaat aggtgcttgg tccattaaga
    50521 taaaatcatc aatagcatca aatccagtaa attcagtata atttttatct gggatagatt
    50581 tttgtttcaa tttttcttct agagcaggaa gtaaactgtg aaatacaaga gagctcttac
    50641 cagaaccact aacacctgta atagagcaca tacagtttaa gggaatttct acatcaatat
    50701 tttttaagtt atttgcatgg catcctttta agcttaacca tttacttggt ataattttat
    50761 tttgtgaact tattttattg tatgtactta aatatttacc tgttatagag tttggatttt
    50821 ttataatttc ttgggttgta ccttctgcga taatgaaccc cccttttgta ccagcacttg
    50881 ggcctacatc aataatataa tcagcagaca gtattgtatc tttatcgtgt tccacaacta
    50941 taacagtatt acccttatct cttagctctt ctatcatttt gatgattaaa ttatggtctc
    51001 ttgggtgtaa accaatagat ggttcatcta aaatgtaggt taagcctact aattcacttc
    51061 ctagctgact tgataatcgt actctctgca gttctcctcc agataaagtt ggagctgttc
    51121 tatctgttga tatatagcta agacctacct ttaatagata actaactcga atttttaatt
    51181 ctgttaagat atcatttacc aaagagagct catttttttg aaggtgattt ggtaattcac
    51241 acaaccaatt ccataactgt tctatcgtca tttttgttag ttcagggaag cgataacctt
    51301 tgattgtagt gaatctagcc tcaatgcaca gcaattcgcc accacatgta ttgcaaggaa
    51361 ttttgttcat atattgatgc aaggtattat tttcagaact agattctcta aaaagtcttt
    51421 gaatgtggtt gattgctcct gaagcaggtc ttctaatctt tgattctcgt ccctttgatt
    51481 caaagctaaa ttcatatatc ttatcgtctg taccatataa gattgcatct ataaaatctc
    51541 ttggtaattc attccaaggt atatctaggt ctatattttt atcttttgct attgcatata
    51601 attcacctac catccaatta ccatttggct ttttccccct caattttcca aaatagtaag
    51661 tagctccatc taatattgaa atagttgggt cttttacaat taattgagga ttaacttgat
    51721 aggtaaaacc taatccatta caatcgtgac aagctccagt atgggagtta gcattgaagg
    51781 ttgaagtatt tatcttagaa aaaatagttt gacaatgtgg acaataattt tttgtattat
    51841 tctttttttc taatggaatt ttgcaatatg gacagtaact ttttccgatt gatacaaata
    51901 acattcttaa ataatcccaa atgcttgtaa gagtaccaac agtagagcga ggattttggc
    51961 ttcctttttt ctgttcgatg gctatagtag gggttaatcc ctgaagtaaa tcaaattccg
    52021 gtttttgaag ctgttctgaa agttttgctc cgttacttag attttcaaaa taacgtcttt
    52081 ttccttcttc ataaatcgta tcgaaagcta aagaagattt tccactacca cttacacctg
    52141 taataacagt tatttgattt tttggaattg taacttcaac atcctttaaa ttgttttgcc
    52201 ttcctccttt taaatagata gagcttttat tatgacaaag tgaattttta attgatttat
    52261 ttattgcttt tgtaaatttg aatttctttt ctagttcaag aggattgcct aattctttta
    52321 tttccgaaat acctaatatt tttaactgag aaaagattga tttcaaataa tcttcaggca
    52381 atttttctat taacaaatta agggcttcta tttttatatt tccgcttgat aatatctctg
    52441 ccatttcatc taataaattt ttttctgctc ttgttaattg attgtatttt ttggaactta
    52501 attctgtcca taaatcccat ggaagcaatt ctaaaccaat catattatta aagtcatgta
    52561 gaagattacc ctttacagaa tgccaacctt tccaattttt attatatcca aagtcatctg
    52621 gatgagcatg tccttgccga catcttatcc aggcttctga accagttaaa aaaccatctg
    52681 tttttccgac atcatgagtg tcaaaattaa tttgaaaata atttttttgt atgtcatcta
    52741 tttgtgcatc tattcttatc catctctttg ttagagtatc atagtattct acaagccagt
    52801 ggtcttcata agtaagctca ctttcaaaat aattagcaaa acctgctctc attctagcct
    52861 caaaacctcg atatcttagg agcgatacaa gaagtaaaga ataatctctg cacattccaa
    52921 caagcctttg ttttgggttt cttggaatag ttagtgggtt agaatttatt tcaaatattc
    52981 tttttaacat ttgaggaatt gtacgaagca attcctcatc agattgttgc ttattaaagg
    53041 atataccata taattttcct tggtctccat gaattactag gctttgaacc acttttaata
    53101 actcaattgg agtctttggt aaatcttgat atttattttc aaatttttta ggatttgtga
    53161 tgatactttg atttttatag ttatttattt tcatttatat ttcacctctc taaatggatg
    53221 atataccctg acatggtgtc atatgcaagg acaatttaga tttttggcca aaatttaaaa
    53281 aataaataaa aaatgataca gtgataaatt gtaatacaaa tatagtttca aattgcatat
    53341 aatataatta tttaataaaa ccattatcta ttgaatgtta atgaaatgtt aagatggcat
    53401 tcttgaatat taagaaatag aatactataa tatagtgtga aggattttta gtaaaaaaat
    53461 ttgtaagtgt taatatacat taaaaaatag gtttataatt tggaggaaaa aaatgaaatt
    53521 atcaaggtat aagaaaaata gtttagttct gtctataatt ttatgttcac ttattatttc
    53581 aatccttgta attactgttt ttaataccgt aaaactacac aatatatcta ataaacaatc
    53641 taaaaactat ttaaatgatg tatctacaca gattgtaatg aatgttgatt ctaaaatcaa
    53701 atttatttta tccgacttaa gaataatggc agattttatt aagcaatatg aaggtgatag
    53761 tcgatatgag tatttatcta aaagaaagac tagttataag tattatgatg ttggaataat
    53821 agatttagaa ggtaaagctg agtttttaag tggaaaaaag tttgacttaa agaatactgt
    53881 ttcctataaa aaaggaattg aaggtaaaga atactcagaa gtaatagagt caatgggttt
    53941 tgttctttat agtgtaccta tatttaatga taatcatgaa gtatctagta ttttaatagg
    54001 tgtatccaat aaagaaagta tgaatgagat tcttaatata gataacttta atggaaaagg
    54061 aactattgaa attattaata gtaagggaaa acctcttttc ataggaaaaa atactgaatt
    54121 aataaaggac cttagccata aatataagag ttctggagat gaaccttggg cacaaaagat
    54181 gcttgaggat tttaaaaatg ataaatcagg gaatattaca ataacctcat caaaaggtgt
    54241 acaatgctta ttaacttatc atccaattac aagaggttta aatgattggc attttcttct
    54301 catagtacct gaagatgctg tacttggtga acttaataaa ttaaactctt ttacaataac
    54361 aatgacattt ataattacat gtattattgg aattataaca ttaattttat atattataag
    54421 aagaaaatat gtaaatcaaa tagaaaatat tgcatattta gatagtataa caaatggtat
    54481 aaattcaact aagtttagta tgctagtcaa acctttaatt tcagaatcac ctgatagtac
    54541 ttatatgatg atagcaatga atataaaaga ttttaagcta ataaatgatt gtttcggtag
    54601 tgaaaaggga aatatgacac taaaacatct ttacaatatt ttgtataaaa acattgatga
    54661 aaatgaagaa tttgtgtgcc gtcatgatgc agaccttttc tatttgctta ttaagaatag
    54721 accagtgtta gaagccctgg agttattata taaaatagaa gctgacacaa attattttaa
    54781 taaaaatagg gaaaatccat actttttaag actatcagta ggtatttaca caattgaaaa
    54841 tcataatgaa gatttaatta caatacaaga ccatgcaaat acagcaagaa aaagctttaa
    54901 taaaactcat caaagtgatt tttcttttta tagtgatata gaaagaaaac gattaatatc
    54961 tgaaaaggaa atttcaaatt taatggaaaa agcccttgaa aataaagaat tttttatgtg
    55021 cttacaacct aaaattgata taaaaagtgg aaaaattagt ggagcagagt ctcttgtgcg
    55081 ttggaaaaat tcagaaaagg gcataattta tccaagtgat tttattcctc ttttcgaaaa
    55141 aagtggattt atatgtaagt tagatttata tatactagaa gaaacatgca aattgatttc
    55201 taagtggata aaagaaggta aagaagtgtt gagaatttct gttaatgtat cacgtcaaca
    55261 tctgaatgat aaattgtttt tagaaaaata taagcatata tgcaataaat acaatgtacc
    55321 aacatgtctg atagatttag aacttaccga atctattttc ttagaaaatc cagaagctat
    55381 agatataata gaggatattc attctaatgg atttaaatgt tctatagacg attttggatt
    55441 tgggtactca tcattaggaa tattaaagga ttttaaagtt gacataatta agttagaccg
    55501 ttcattcttt gttagcaaaa ataatataga ccgtggtaag gtagttatta agtctattat
    55561 tgaacttagc aaaaggctag gtatgaaagt aactgctgaa ggaattgaag aattagaaca
    55621 agttgagttt ctaaaaaatg tgggatgtga ttatattcaa ggttatgttt tttcaaaacc
    55681 attattaatt tctgattttg aaaattttgc atatgaaaat aataaaatta aaaatatcca
    55741 ttattaaatg tacaagataa aaaatttagg caagttatat aattaaaaat ataacttgtc
    55801 ttttttattt atatatttaa taaaaatata tttgcagatt ttgtaaaaat aattttcaaa
    55861 tgttgtaagt tgtggctaaa gctttattgt attattctga atatagaaag atagttactg
    55921 tcttagataa aaactgaaac atacataata atataaaatt tgctatatta ataactctaa
    55981 ttattttgga aggagggaaa atatgataag tgggagaatg ttactcatca tgaattttct
    56041 aaaaggaaaa aataagacaa gttacaagga tattagcaaa caacttagta tagaagaaag
    56101 aaaagttaga tatgatataa ataatttaaa tattgttttg cgttcattaa acaagtcagt
    56161 aatacaaaag atgaacaaag gtgtgttaat tattcctgat gacttccaag tagtatgtat
    56221 aaataataac gaatatgtat tttccttaac tgagcgagta tctattatga aaattatatc
    56281 aatgtttaaa atagataatc taaacttaga aaaattaagt aaagaatttc aggtttctag
    56341 aagttcaatt aaaaatgacc ttaatgtttt gtcaagtgaa ttagaaagaa accaaataac
    56401 tattacttat gataaatctt ttaaaataag tggagaagaa gacattatat ataagcaaag
    56461 attgaacata ttaaaatcgt attcttatct ttttggtaag gaaaaatctg atttaagtgt
    56521 atttgagaag tatttagtga atgtaattga aaaaatattc aaagggattt atttgattga
    56581 tatatataat tggtctatga atttattatt gcaaatggga tggactttaa atgatgaatc
    56641 ttttacatgg tatgtgtcaa acattttcct ttttacatgg tatatacatt cagatgaaaa
    56701 acatccttta gaatctgctt cattaagtga gccgtgtttt gaaaataagt ttgaccaaga
    56761 atttgaaaca attattcaaa aaaagttgac taaggaacaa atttttctgt taaagagttt
    56821 tgtatttttt acaaataaat atgcaagttt aaacgaggat atggatttga ttagtacaga
    56881 aattatagtt caagatctaa tttacaatat gtcagaaata ttagagatta gctttaaaga
    56941 agatatgatt ctttataaag gattactcaa tcatattgcc ccattgatag agagaatcaa
    57001 acagaatata cagatttatg aggaattact tcatgtaata ccagataaat atcaatatgt
    57061 acttgaagct actaaggttt ctattcaaaa aaacagagtt ttaagtcaaa taaagaatga
    57121 aaatgaaaca atacttttgg caatacattt cttaggaagt atacatagaa atgagaggaa
    57181 taactacaaa aatatattgt tagtttgtgg atttggatat ggtgtaattg ctatgttaaa
    57241 ggatagttta gtaaatgatt accagataaa tatagtagag agtattccat catataagtt
    57301 acaagattat aaagaatggg aaagtattga cttcattata acaacatcaa agatagtaat
    57361 agacttgcct aaaacaatta ttgagataaa tccattttta caagaagagg attatttgaa
    57421 gtttgaagaa aaagggataa aaagaaagaa cgtcttaact aattatatgt caataaaaaa
    57481 aaggttggac tttttagaag aagatgccca aaaaagagta ttaagtatta tatgtcaaga
    57541 acttggatac agtgatgaga gaatattatt tagacaactt aatttaagtg atttaatagg
    57601 aattgatacc ataaggataa ttgatggaga tatgaaatgg gaagatgctg taaaaattag
    57661 ttcaaacata cttgctaatt gtgattttgt atcagcacaa tatgctgaga atattataga
    57721 tattttaaaa aatgtgggtt tttatgctgt aaaagataac gaatttgctt tactacatgg
    57781 caatgatagt tcattagtca aagtaagttc gataagttta ttaatatgta aagaagcagt
    57841 tagttttgga gataaaaagg ttaaaatcat attttgccta gcaagcagag ataaaaaaga
    57901 gcaaattcct gcaataatta atctaactaa aatggtttat aagactaatt ttattgctat
    57961 gttagaaagt gcaaagacaa aagaagaagc agaagtttta attcataaat atgagaagga
    58021 ggtcactgta tgaataaatt agttaatgta aaatgttcat ttaaaataca tgttaattca
    58081 aaagaagaag ccattatatc gttagttgat gtagtgtcaa aagaaggata tttaatagat
    58141 aaaaatcaat ttttaaaaga tgttttaaag agagaagaaa cattgtcgac ttatattgga
    58201 catggtatag gtcttcctca tagtcaaagt gtaggtgtta aaaactcttg tattacaata
    58261 ggaaagcttg atactcctat tgaatggaca gaagaaggag aaaaagtgga tttaatattt
    58321 ttgatatcag taacaaaaga caatgaaaat aatcttcatt taaagatttt atcaaaatta
    58381 gcacgtttat tgatgcatga aagttttaga aatcaaatta gatgttcaga tgaacaaact
    58441 gtttataatc ttataaaaga aaaaatagag gaggaagatt aaaatgagaa ttttaaagtt
    58501 tttgcaaaaa catcttatga cagcaacatc ttatatgatt ccatttgtgg ttgcaggagg
    58561 aatattattt gctttatcag taactttaag tggacaagct gctgttcctg aaacaggctg
    58621 gttggctaaa ctgaatcaaa ttggagctgc tggcttggct ttattcattc ctatattagg
    58681 tggatatata gcatttagta tggcagataa accaggatta gctccaggta tgataggtgc
    58741 atatttagca aaagaagtaa atgcaggttt tataggtggt atcatagcag gatttatagc
    58801 aggatttgtt gttttacaat taaagaaaat taaattagct cctacaatga gaactttagg
    58861 ttctatattt atttatcctt tagttggtac attgattaca ggtggtataa ttgtattttt
    58921 aattggagaa cctatagctt cttttatgac atggatgaca aactggttaa atggaatgtc
    58981 tggtgtttct aaaattcctt taggtggaat cttaggagga atgatagcct cagatatggg
    59041 tggccctata aataaggttg ctgctacttt tgcccaaact caagttgaca cacttccata
    59101 tttaatgggt ggagttggcg ttgcaatttg tatacctcca attggtttag gattagctac
    59161 attattgttt ccaaaaaaat ttagcaagga agaaagagat tcaggtaaag cttcactatt
    59221 aatgggatgt gttggaatta cagaaggagc tattccattt gcaacatcag atccagttag
    59281 agtaatacct tgtattatgg ctgggtcgat tgtaggaaat attatggctt ttttattagg
    59341 atgtttaaat catgcaccct ggggaggtct gatagtgtta cctgtagttg acaataggtt
    59401 ggggtatatt gcatcagtat taactggagc agtagttgtt gcggtattaa tgaaattagt
    59461 aaaaaaagac gtgaaagaag atgaagaaat tgaagaagat ttagatgaat caattgaatt
    59521 aatatttgaa gaattataaa tataaatgga aggaatttgt ataaaaaagt aaatataaaa
    59581 ctataaattt aaaggagata agaatatgaa aattgtagca gtaacatctt gtcctagtgg
    59641 agtagcacat acttacatgt cggctgaatc acttgaatta tcagccaaaa aatttggtat
    59701 agaaataaag gttgagactc aaggaagctc tggaatagat aatgaattgt cacttaaaga
    59761 tattgatgaa gcaacttgtg taatattgac taatgatgtt gagattagaa atatggaacg
    59821 ttttaaagga aagaaggtag taagaatgag tgtatctgag ataattaaga aatctgatgc
    59881 attaattaag aaaataaaag atacttttca ataaaaattg atttatttta catataactc
    59941 aaagatgttt ttaaagaaat ttttattaaa agcatctttg aaaatatctt aaaaatagaa
    60001 taaaaggaga tatagtcatg aaaaagttac caataaagac tgtcgtgcaa agattactaa
    60061 acttacaaga agaggggaaa agtgcaactc ttttaggaat tggtcctatg tcaccaaact
    60121 tgttacaagc aagttttgaa ctagcaaaag atgatgattt tcctttaatg tttatcgcaa
    60181 gtagaaatca agtagatgca gatgaactag gtggcggtta tgtaaatggt tggaatcagg
    60241 aaacttttac aaaagatatt aagaaggttg ccgacaaagt tggatttgat ggtttatatt
    60301 atttatgtag agaccatggt gggccatggc aaagagataa agagagaaat gaccatttgc
    60361 ctgttgatga agcaatggag ttaggaaaaa aatcttattt agcggacatt gaagcaggtt
    60421 ttgacctatt gatgattgac cctacaaaag acccatttga aattggaaaa gtaattccac
    60481 tagatgtagt actagaaaga actgtagaat taattgagta ttgtgaaaac gagagaaaaa
    60541 gacttaatct accagacata ggttatgagg ttggtacaga ggaaaccaat ggaggtctga
    60601 cttcaactga gacgtatgaa acatttataa ctagactaaa ggttgaactc gataatagag
    60661 gtttgccaat gccaacattt atagttggtc aaactggtac tttaactaga aagacagaac
    60721 aagtaggaac ttttaatttt agaaatgctt atgatttagc tcaaatggct aagaaatatg
    60781 gagttggttt aaaagagcat aatggcgatt acttagatga tgtaacttta ttagaacata
    60841 taccatctca aattattgct acaaatgtag ctcctcaata tggtactgaa gaaactaggg
    60901 catatttaaa attagcagaa gttgagtgta aattagaaaa agagggctta gttgagaaaa
    60961 cttctaatat cagacatgtt cttcttgtta atgcaattga atgtggacgt tggagaaaat
    61021 gggtagtagg agaacaaaaa aatctaacta ctgaagagat atttaaggat gaagttttat
    61081 ctaatgaaat actagatatt gcaggacatt atacatttaa taatgatgat gttaaaaaag
    61141 aaatagaagt gctttatgat aatttaagta agaataatat tgatggtcaa agatttgttg
    61201 tagaccatat taaacgtcct ttgcgtgatt atgcagaatg ctataactta aaaggtgtta
    61261 ctacgaggat tttaaataaa taataggact tatagtggtg agtattgtta tactaggtat
    61321 ttatagttat aattatactt accactatta aatttaggag gactaatatt ttgattaatt
    61381 taatttttga tgtagatgat actttatata atcaattaac gcctttttac actgcatata
    61441 ataaagtgtt ttcttcaata aaggatattt ctattgaaga tttatatatg agtagtagaa
    61501 agtatagtga tgaggtattt catatgactg aaaatggaga aatgccaatc aaagaaatgc
    61561 atatttatag gataatgaaa gcttttgagg agttgggaaa ttctattaca gaaaaagatg
    61621 cacaaagttt tcaagatgag tatatatatc aacaatcaca aattacacta ataccagaag
    61681 ttgagaggat tttaaatttt tctaaagaaa gaaatattaa tctaggaatt ataactaatg
    61741 gcccatcaaa ccatcaaaga atgaagttaa agcagttaaa tattgaaaac tgggttgata
    61801 aaagtaatat ttttatttct agtgaggttg gattttctaa gccagatact aatattttta
    61861 gagtagctga gaatgttatg aatttagata gagaaaatac atattatgtg ggtgattctt
    61921 atagaaatga tgtattaggt gctaaaaaag ctggttggaa gagtatatgg ttgaaccata
    61981 ggggacatga gttagaagag ttgttttata aacctgattt tgtaattttg gaacataagg
    62041 atttgatatc tttatttata aaaatatgta gttataaaaa tatgtagtaa aaaaatgtta
    62101 ataatagaat tgtataaaat aattaataat aactatataa aattatatgt ttagattgtg
    62161 agcaatctat tttatgttaa aaatagatta tttagaagaa ggggaaatct taaaaaaatt
    62221 tgaatatccc ctttttatta tttaattaaa atgaaatagt tagaaatata ttttatttag
    62281 tttagtcaat aacattttgg gattctttat aactacatgt taactgttga ataggtttat
    62341 catatggttt aacccatcct ttattaatac ttaattctgt aagtgctgtg tgaccttcta
    62401 ccatttgagt taatgaagct gaatatatag ctcttagttc aggtgtacta cttgtcaatg
    62461 cagaattaag atacatattg gcagatgctt tagcagatga aagcatactt aacattatta
    62521 ctttatcgtc tatataagta ttgttcttaa ttagattttc tatcatattt ctcatgttat
    62581 ctatacctcc tcagaaatta gtatttcatt ttcaactata aattgttgta tagctttaat
    62641 tcttccttct gttgctaata tactagattc tgattgtctt tttagatctt catctgatat
    62701 taacatattt attgctcttt gcataagtaa tccgtcagac tccattttta taattgctgc
    62761 taaagatatt ttttcagttt ctgaaagtat tctcatttaa tcatctccta tattgtaatt
    62821 tatgctttaa tagtatgtct ttcttttcaa ggaaataacc attacacttt tttacagtat
    62881 tttatattct cgttatatca aaatttagtc gacttaatat attaatataa ttttgtagga
    62941 tatttatcat taaatatcta taaaataaat tgtttgaata ttcataaagc aaaatttatt
    63001 tgtatgtact tcttcaagag taaatatgag ttttttcaaa aaattaattt ttatgataat
    63061 tattaagggc tatatttttc ttaaagttgt gattatcatt attaatttac aataaaattg
    63121 ccgaaaagcc ctctccttta ggtgtaggga tgaaaggtaa ggtcttaata taaaaaagtt
    63181 agaataatgc ttgtaatcta ataccgcta
//
LOCUS       DAMJWC010000015        62036 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMJWC010000015 DAMJWC010000000
VERSION     DAMJWC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.015"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(372..2156)
                     /locus_tag="PC503_001143"
                     /pseudo
     CDS             complement(372..2156)
                     /locus_tag="PC503_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
     gene            complement(2940..3128)
                     /locus_tag="PC503_001144"
     CDS             complement(2940..3128)
                     /locus_tag="PC503_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527153.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3154..4293)
                     /locus_tag="PC503_001145"
     CDS             complement(3154..4293)
                     /locus_tag="PC503_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2527154.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDELYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFISKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4830..5669)
                     /locus_tag="PC503_001146"
     CDS             complement(4830..5669)
                     /locus_tag="PC503_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2527155.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5693..6451)
                     /locus_tag="PC503_001147"
     CDS             complement(5693..6451)
                     /locus_tag="PC503_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2527156.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6498..6971)
                     /locus_tag="PC503_001148"
     CDS             complement(6498..6971)
                     /locus_tag="PC503_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527157.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(7000..7416)
                     /locus_tag="PC503_001149"
     CDS             complement(7000..7416)
                     /locus_tag="PC503_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527158.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIVINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7463..8515)
                     /locus_tag="PC503_001150"
     CDS             complement(7463..8515)
                     /locus_tag="PC503_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2527159.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8911..9591
                     /locus_tag="PC503_001151"
     CDS             8911..9591
                     /locus_tag="PC503_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2527160.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9724..10044)
                     /gene="sugE"
                     /locus_tag="PC503_001152"
     CDS             complement(9724..10044)
                     /gene="sugE"
                     /locus_tag="PC503_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF2527161.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10426..11253
                     /locus_tag="PC503_001153"
     CDS             10426..11253
                     /locus_tag="PC503_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2527162.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12075..12749
                     /locus_tag="PC503_001154"
     CDS             12075..12749
                     /locus_tag="PC503_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527163.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            12737..13897
                     /locus_tag="PC503_001155"
     CDS             12737..13897
                     /locus_tag="PC503_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2527164.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            14113..14640
                     /locus_tag="PC503_001156"
     CDS             14113..14640
                     /locus_tag="PC503_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF2527165.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFSSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            14926..15594
                     /locus_tag="PC503_001157"
     CDS             14926..15594
                     /locus_tag="PC503_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527166.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            15597..18065
                     /locus_tag="PC503_001158"
     CDS             15597..18065
                     /locus_tag="PC503_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527167.1"
                     /translation="MKNYLSLSIKELKSQKFMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(18305..19729)
                     /locus_tag="PC503_001159"
     CDS             complement(18305..19729)
                     /locus_tag="PC503_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527168.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(19748..20440)
                     /locus_tag="PC503_001160"
     CDS             complement(19748..20440)
                     /locus_tag="PC503_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527169.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(20492..21271)
                     /locus_tag="PC503_001161"
     CDS             complement(20492..21271)
                     /locus_tag="PC503_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2527170.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(21268..22038)
                     /locus_tag="PC503_001162"
     CDS             complement(21268..22038)
                     /locus_tag="PC503_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2527171.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(22035..22739)
                     /locus_tag="PC503_001163"
     CDS             complement(22035..22739)
                     /locus_tag="PC503_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2527172.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(22994..23506)
                     /locus_tag="PC503_001164"
     CDS             complement(22994..23506)
                     /locus_tag="PC503_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527173.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSDCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            23832..24089
                     /locus_tag="PC503_001165"
     CDS             23832..24089
                     /locus_tag="PC503_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527174.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            24232..24858
                     /locus_tag="PC503_001166"
     CDS             24232..24858
                     /locus_tag="PC503_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF2527175.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(25105..25884)
                     /locus_tag="PC503_001167"
     CDS             complement(25105..25884)
                     /locus_tag="PC503_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2527176.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(25952..26413)
                     /locus_tag="PC503_001168"
     CDS             complement(25952..26413)
                     /locus_tag="PC503_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2527177.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(26389..27066)
                     /locus_tag="PC503_001169"
     CDS             complement(26389..27066)
                     /locus_tag="PC503_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2527178.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            27299..27685
                     /locus_tag="PC503_001170"
     CDS             27299..27685
                     /locus_tag="PC503_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2527179.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            27688..29487
                     /locus_tag="PC503_001171"
     CDS             27688..29487
                     /locus_tag="PC503_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF2527180.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(29842..31716)
                     /locus_tag="PC503_001172"
     CDS             complement(29842..31716)
                     /locus_tag="PC503_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2527181.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(31721..33385)
                     /locus_tag="PC503_001173"
     CDS             complement(31721..33385)
                     /locus_tag="PC503_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2527182.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(33399..34220)
                     /locus_tag="PC503_001174"
     CDS             complement(33399..34220)
                     /locus_tag="PC503_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2527183.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(34319..35083)
                     /locus_tag="PC503_001175"
     CDS             complement(34319..35083)
                     /locus_tag="PC503_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2527184.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(35080..35829)
                     /locus_tag="PC503_001176"
     CDS             complement(35080..35829)
                     /locus_tag="PC503_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2527185.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(36333..36938)
                     /locus_tag="PC503_001177"
     CDS             complement(36333..36938)
                     /locus_tag="PC503_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527186.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            37117..37755
                     /locus_tag="PC503_001178"
     CDS             37117..37755
                     /locus_tag="PC503_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2527187.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            37887..38549
                     /locus_tag="PC503_001179"
     CDS             37887..38549
                     /locus_tag="PC503_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527188.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            38549..39730
                     /locus_tag="PC503_001180"
     CDS             38549..39730
                     /locus_tag="PC503_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527189.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(39911..42571)
                     /locus_tag="PC503_001181"
     CDS             complement(39911..42571)
                     /locus_tag="PC503_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527190.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(42568..43251)
                     /locus_tag="PC503_001182"
     CDS             complement(42568..43251)
                     /locus_tag="PC503_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527191.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKQFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(43595..44548)
                     /gene="blaCDD"
                     /locus_tag="PC503_001183"
     CDS             complement(43595..44548)
                     /gene="blaCDD"
                     /locus_tag="PC503_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2527192.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(45089..47203)
                     /locus_tag="PC503_001184"
     CDS             complement(45089..47203)
                     /locus_tag="PC503_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HDF2527193.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(47461..48321)
                     /locus_tag="PC503_001185"
     CDS             complement(47461..48321)
                     /locus_tag="PC503_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527194.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(48916..49278)
                     /locus_tag="PC503_001186"
     CDS             complement(48916..49278)
                     /locus_tag="PC503_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2527195.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(49512..49976)
                     /locus_tag="PC503_001187"
     CDS             complement(49512..49976)
                     /locus_tag="PC503_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2527196.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(50405..51826)
                     /gene="nhaC"
                     /locus_tag="PC503_001188"
     CDS             complement(50405..51826)
                     /gene="nhaC"
                     /locus_tag="PC503_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2527197.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(51856..52920)
                     /locus_tag="PC503_001189"
     CDS             complement(51856..52920)
                     /locus_tag="PC503_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF2527198.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(52905..54314)
                     /locus_tag="PC503_001190"
     CDS             complement(52905..54314)
                     /locus_tag="PC503_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF2527199.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(54314..56518)
                     /locus_tag="PC503_001191"
     CDS             complement(54314..56518)
                     /locus_tag="PC503_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2527200.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(56512..56886)
                     /locus_tag="PC503_001192"
     CDS             complement(56512..56886)
                     /locus_tag="PC503_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF2527201.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(56964..58394)
                     /locus_tag="PC503_001193"
     CDS             complement(56964..58394)
                     /locus_tag="PC503_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF2527202.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSYFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(58387..58695)
                     /locus_tag="PC503_001194"
     CDS             complement(58387..58695)
                     /locus_tag="PC503_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF2527203.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(58839..59906)
                     /locus_tag="PC503_001195"
     CDS             complement(58839..59906)
                     /locus_tag="PC503_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF2527204.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     NVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(60162..61535)
                     /locus_tag="PC503_001196"
     CDS             complement(60162..61535)
                     /locus_tag="PC503_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527205.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGREITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        20900 a        10472 c         7291 g        23373 t
ORIGIN      
        1 gcctcagctt gtacttctgc ttgtatttcc ccatctgttg atttggctgg tactactaca
       61 tctatttctc ctgtatctgc tgttttacca cttgattctt gtgttactgt aaataccaat
      121 gttactgttt cctctgtatt tggaggtatt attgttccat cttcctttat aacactctta
      181 ttgcttgatg tttttattgc tatagtatat ccacttgata ctgatggcat agttaattta
      241 gttgcatctt ttgctggtgc aggaacgctt gttatttttg ccacttcatt gtctaatgct
      301 gcttgtaatt cttcatctgt tgatttagct ggtactgtta cagataattc ttttgtatct
      361 gctgttttac cacttgatgt atgtgttacc gtaaatacta attttactgt tgttgctgta
      421 tttggaggta ttattgttcc atcttttttt ataacactct cattacttga tgtttttatt
      481 gctatagtat atccacttga tactgatggc atagttaatc tagttgcatc ttttgctggt
      541 gtaggcacgc ttgttatttt tgctgcttca ttatttactg atgtttgatt agaagaactt
      601 cctcctgaag atgagcctcc tccatgtgaa gaacctccac ttgatgaact tcctcctgaa
      661 gagttagaac ttggactatt tccacttatt gttggagaat tatctccctt aacactactt
      721 attgtacctt tattatctat agtagtccct ttagaattat ttgtaactgt agttatctta
      781 ccaccattag tcacttttac ttgacttgct ccagatgcta ctgttaaact accaatctca
      841 cctttagaat tattttctat cttggctcca tttttatcat taacctttaa gttagttatt
      901 tttccataat taacaaaagt tccatctttt acatcatcta taactacatc atccactttt
      961 gcatagttat ttacatcacc attaggcatg ttgatagtca cagtctttgt atatgtacca
     1021 tttaagttta ctgttactgc tttatcagtt tgtattgtaa atgcttcttt aacctcacta
     1081 gttggcttaa agtttataac atcattagca gtagctttat ctatagctga ttttaattca
     1141 gaaattgttt tagcttcaac tgtttttact tcttgtaatg acttcatttc attaaatgct
     1201 gtctcattac cattcccacc aactttagtt atcttatcaa aactcttaga gttaactaga
     1261 gatttttgtg aagctgataa gttctttcca actaaaacta ctggtgattg atttttagca
     1321 cctaatacac ctactgctag tgcatctata agttggtctt gtttattcat accatcttta
     1381 gttacataag cattttttaa atctgtcttt ttataaaatt cttttattac ttttgcattt
     1441 gtatcatttc tatctgttcc acctagtctt gtactatttg gtagtttatt tttaacagct
     1501 tcagaaattg aactctctcc acctactaca taagattgag ttattccagc atcctttata
     1561 aatttgtctg caactgctgt tccattttta gaatcagcaa gtattactgg catattgttt
     1621 tgtgcagctg gtgctcctac acttacagca tctgcaagtc ctttttcacc attaactaca
     1681 gctattttct taacatcact tatagcatct aatttctttg ctaattctaa ggatgtttga
     1741 tatctctcag ctccagagat tctctcaaaa gatattttta aatcttttat ttctttttct
     1801 atatttgtac ttaatacaga agttccacct attaagtata cttttttagc ttttaatctt
     1861 tgtatttctg ctttcgtctt atcatttaat ttatctttac ttgttaaaag tattggagca
     1921 ttttttgctt ttgcaaatgg tgttgcagat agagcatctg ctatagatga gtcgtttacg
     1981 attactacct catcagcatt tttccatcca tcttgactta ttttaacagc agtttcatat
     2041 ctttcttgcc ctgttaaatt tgttgccaca gtttgtgcac tagctatgcc tgctgttgaa
     2101 cttccagcta tcattgtaac tgtaagcatt gcagcaatct tctttggtat tttcatttta
     2161 ttttcttccc ccttgtccat ttgatattac ttaatttttt aactttgttc ccgttctaat
     2221 tctaaaggat acttaatatc taattttaaa gaggtttcta actataatga tttcataatt
     2281 aatttgtaat tattttgtta cattgcagtc attatgtaag gaataaagaa attttcttat
     2341 tgattgaaaa atttgtaaat ttatatttta aggtaagttt gatttttatg ttaatgaatt
     2401 gttataaaaa atagggtttt gtataaaaaa agtagccttt agaattaaaa gtgctactct
     2461 ttttacaaat aaattttatt atttatactt gtaattatat attaaataac caattttatc
     2521 catatgaaaa acaaataatt gcgatatttt tttaattatt ctttatattt acattttaat
     2581 tcaaattact tttgtaaaga ttatatctgt tgcatatact actttaagtg ctaatatctc
     2641 tccacctcaa ttagaatcct cgttatctca atagacgttt tctactgtca aagttaccaa
     2701 catttgaaac ttattaaatt tttatataaa aaagacctag aatataaatt ccaagtcatt
     2761 ttttattaaa tttatttttt acaatataat attgtcatga ttaaagaaca caaatcatac
     2821 acaaattggt cataaatctt acataaatca tctacaaaaa atacattatt tatattaaat
     2881 ctatataact aaattaagag catattgtac aatatgctct tagaaaagat atttcttgtt
     2941 tatagtttat agtatttctc tatgattttt atttttatca tttcaaaaat aaaaattaag
     3001 attacagtta ttatcatatt ttgtgtacta ttttctataa tattataatg aaacaatgaa
     3061 aaaacaataa ttaatgaaat tacgtttata gccccagaaa tcaaaaatgc ctttttctta
     3121 ttattcatat attccctctc cagattatct aaattagtct atatcaagca tttttaagta
     3181 cttatcatta actttatata tatttttttc tttagacaaa atctctatct cttcaagatt
     3241 attaaacact tccatcaact ggtcaactaa ttcaatttcc tttattccag cctttaagta
     3301 tctactttta ttctttttta tataattttc taatgtcata gaatagttat ctttattgca
     3361 aatatatttt aatatatgtt cttctgttgc tgatagagtt atgtcatttt caaacaattc
     3421 ttcttttaat atactttcta aagattttct atcatgcata ttacgcatct cattaataga
     3481 ttgtattata gacttgagca taaattctat aaatacagtt aaattatttc ctttgttttc
     3541 tacatcaagt atagccttat aatacttagt tctgttttta gatatcatat atgatattga
     3601 aaaatccttg aaagtatcat atcctttatc aatcaaatat agatatgata aggctcttga
     3661 tgttcttcca ttaccatcac taaaaggatg aacatataca aagtaaaaat gaattatagc
     3721 acttttaatt aaattactta ctttgctatt ttccataaaa tctattaatt tactaataaa
     3781 gtcatatatc ttcaaaggtt caagccctgt atgtataatc tcaccttttg aatcacatac
     3841 atatactttt tcagttctat actcatattc ttctgaatcc aagcagtttt cgcccaatat
     3901 atgatgcaaa tcatatataa atttgtgact atacaattca tctaagttat ctaatccata
     3961 ttctaaggct ctatgattat tgtaaatcat atattcactt ttattacttg gtttcatctt
     4021 tcctctaatt atagattttg caatctttct agttgaaaaa gcaccttcta ttacactaga
     4081 ataataagac tctagtgcca aatcattttt atcttctatt gttttaaata tcttacttga
     4141 tgttaattta tctatttcat ttattaaatt taatatattt tcagtttcat gatagtatag
     4201 ttctttatta tcaaaactat ttatagaaag tacgatttta tttccagtaa agtatttgtt
     4261 tttgtattct tctattgtca gtttaatcac caccttagat tatctttatc tattaatatt
     4321 aacaaaaagt attaattttt acactatttt tgattatttg ttttataatt atcaaactca
     4381 atttagcgtt aaagcataat aaattttaat aaataatgca aaaatttaag aataagcatt
     4441 taaaatatat gttacaggaa gtttacaact attatttata atacattagt tatatattat
     4501 aatatctcga caatgtctta acaatatctc gattatatat tttaatatgt aactaatatg
     4561 ttataatatt ttaattaaat taaataaatt tatatttttt tgaaattact taatatttta
     4621 tataaaaatg aaaaagcacc tcattctgat taaaaatctt tctgagatac tttttaaaat
     4681 attaaatact acatatagct tacataagtt taaaatttaa tctattataa aattacccta
     4741 attgccaaac tttttaatat aaattttcca acatcctaca aatataatca atagatatag
     4801 aatcctaact tacaccaata tatatttatt taaaatagtc ctaaaatacc tgtaatagct
     4861 cccactacta tcagtataaa cattattttt attggagaaa gacctttttt taatgcaaag
     4921 agtactaata aagtaagtac caaaggaatt aatcctggaa atatcttatc aagtaaatcc
     4981 gtttgaagac taaatttaaa atcaccacta gtataactta ttggtgtaga taaattgata
     5041 aacctaccta caagcccccc catgactaag gtacctagta tagaagcccc ttctataacc
     5101 ttatttacta ttccaccttg aagtatactt tcaacagctt ttttcccata cttatatcca
     5161 tttgtccaca ttccaaaaga aattgaagtc attattatat attgagctat tacaaataat
     5221 ataggtcctg caattgatgc tcctccctca gttaaaccaa tacaaacagc taacactata
     5281 ggagttataa ctccttgagt taaagtatct ccaattcccg ctagtggacc catcaagcct
     5341 gttttgatag cattcatacc atctccactt atttcatctg ctccattagc tttttcttct
     5401 tccatagcta ttgttattcc atgtataaca catccacata taggttctgt gttaaaaaat
     5461 gctagatgag tctccacttc ttgttttaac tcttccttat ctggatataa ttttttaagt
     5521 actggcaaca ttgaatgtga aaaagctgtt gattgcaatc tttcataatt gtaattagat
     5581 tgtgcaaaga aaaaccatct taaccatgat tttattacat ctttcttgct taacgttttc
     5641 ttagatactt cattttttat atctgacata atattttccc cctcacatgt atttaagatg
     5701 tagcactatc ttttccgtac ttaattgaag taattgtaag agcaagtatt actccaataa
     5761 cagatattac tattatatct actttaaaat aaacagccat tagtattcct aatatgaaaa
     5821 agggcatagt aaacttattt ccaatcaatt ttaaattcat agcaatccca agtgctggca
     5881 acatagcccc aattacatta aatacatgta acacattatc attcattact tccaacatac
     5941 catctatcgc atttggacca aaataaacaa ctaataatgc tggtataaaa ctcattgcaa
     6001 ataacagtat ctgtggtggt actatattta taaatgctac tctatcaaca ttcccttttt
     6061 gaacctctct atcagcccaa tgtgcaaaaa aagaatttac tgtcatcttt ccaatccaaa
     6121 gtacagttgc aacagttccc aatggtacag ctattgccat tgcagtactt acatctagct
     6181 tagatgctat agctaaagca gtacctacat atcctgcaaa agctgggtcc cccatctgag
     6241 ctccccctgc tgatataaaa cctagatata tcatatttat acctgctcct ataattgctc
     6301 cttgaacagg gtctcctaat ataattcccg ttacaaatcc agccaataga ggtctattcc
     6361 atgtaaaaaa tccaacataa gtcaaccacg gactccaaga aagataataa aaaattgcta
     6421 ttaatactgc ttgaattagt gaaatgtgca tattcttcct ccctattttc ttttaaagat
     6481 ttacaagata gtcttcttta caataatgtt cctacatcaa ttttctttgc atctggtact
     6541 atttgtataa agcatttaac atcttttgat attagctctc taaatatttc tttttcttca
     6601 tctgacacag atatattttt ataaaaactt tttctaccaa gccctgctcc catacctcca
     6661 acattcaatt cctttaaatc taccccacta tttactaaac ctaagacagt tttagggtat
     6721 ttgaccaata ctattaaatt ttcatctcca ttatgtgatt ttaagacttc agcacctgat
     6781 tctacatcat gtacttcaac cttaacagtt gatggagctg ccatttgtaa aacttgaact
     6841 ataaatgggt cctttactac taaatcatcc acgattacta tcctttttgc tgatgtaatc
     6901 ttacaccaag cagtaataac ttgcccatgt attaatctat catcaattct tgttaatgct
     6961 atattactca taattattcc tccagatttt taatttattt tacaacttta aaacagtttt
     7021 aacatctttg attcctgata tcccaacttc ctcacataaa ttcttcaagt cttttaactt
     7081 catagtatct ctgtttaaaa ataactctaa aagcataggt aaatttacac ctgtcaaaca
     7141 ttctaactca cataccttag caaatttatt tattacaata gcagatgtat taaatggagt
     7201 tccgccataa aaatcaagca atactaaaac cccttcatcc ttatatttct caattccatc
     7261 ttctaacttt ctactaaact catctatgct gtcaccatgg tttaatccta aagtttctac
     7321 attttcctgt ttgcctacta ttaattcagc actttctaac attgctttag ccatatttcc
     7381 atgtgtggct ataattattc ctgccatatg aatcatacct ttcttaacct tttttatatg
     7441 gattattatt tagtactcta atctaattat ctatattaat cattatctta ccaaagaaaa
     7501 tatccctttt gtatactttt tcaaaataag ctggtacttc ttctaaattt attctatgtg
     7561 ttactaattt ttcaacattc atatcaccct tttgcatatg atacaatcca gcactccatt
     7621 cttttcctgg gaatggaaag gagtttccaa accaagttcc ctttacagtt aattcacttc
     7681 ttactatctt ttcaaattgc tctctagtca aagctacatc cccatatggt acacctgcat
     7741 acaatactgt acctcccttt ttagctagca acagtacttg accacatgtc agtggagtac
     7801 cagccgattc aataacaata tctgcaccat ctccatcagt taaccttttt atttcttcta
     7861 caatattctt ttcttttgca tttatacaaa tatctgcccc taactctttt gccaagtcta
     7921 acttctcatc aaatacatcc acagctatta tttttgtaga accaaatatt tttgcccatt
     7981 gtattgaaaa taatcctatt ggacctgtac caagtactac aacagtatct ccaactttag
     8041 cttctgacct aaaaagacca tgtcctgcta tacatactgg ttctagcgca gcggcagtct
     8101 cataacttat ctcatctggt atttttatta aatttctctc tttcaccttt gtatactctg
     8161 caaaacaacc tccaagttct ttatttccta ttattgctac attattacat cttgaataca
     8221 agcctttttt acattcatca cattcaaaac atggcatagc tggacaaaca gcaactctat
     8281 ctcctatttt aaaactcctt acttctttac caacctgtgc cacttctcca gaaaattcat
     8341 gccctaaaat ttctccaacc atatgtggac ctgtctttga atattttgat atatcagaac
     8401 cacatattcc agctactttt actttaatta ttacatcatc tttttctaat atttttggta
     8461 catccacatc ctccactctt gtgtctctta taccatagaa tctaactgac ttcactatta
     8521 accaccccta ctttttattt gagaatatat ccctattgtt tatatgttaa atatctaaag
     8581 caactttcat gccaatatat gtaagcattg tattcatgca ttttataaaa ttatcattaa
     8641 atgtgtgtca aagtgtgtca aaagtttctt atattaaaac ttatgtgtgt caatataaac
     8701 gacactaaca ttttatatta gttctcttat tataagtttt ataaaatgta ctttttttgt
     8761 tatttttata aaattgttcg gaaatttccc ttctatttgt gatataatat taaatataag
     8821 gtatcaatat aaattttcat gcgaatatca gaactttttt gacactaatg ccttattcaa
     8881 tataataatt taactttttg gaggttgttt atgaaaaaag tgtatcaagg aaagactaaa
     8941 gatgtttttg aattagataa tggaaattac ttacttaaat ttaaagacga tgtaactggt
     9001 aaagatggag tatttgaccc aggcgaaaat agtgtaggtc taagtataga tggaattggt
     9061 agagctaatt tagagacatc tgttaagttc tttgaaattc taaacaatgc tggaattaaa
     9121 actcattatg taagtgctaa tttagaagaa gcaactatgg aagttctacc agcaaaagtt
     9181 tttggtaatg gattagaagt tatttgtcgt tatagagctg taggtagttt cttacgtcgt
     9241 tatggttcat gtgttgaaga aggtgctaaa ctagattgtt acgtagaagc aactttaaaa
     9301 gatgatgacc gttgtgaccc tcttataaca tctgaaggtt tagaagcttt aaacattatg
     9361 actcaagctc aatttgattc aatgaaaagc atgactcaaa aaatttctaa catagttcgt
     9421 gatactatag ctgaaaaagg tcttgagctt tatgatatta aatttgaatt tggattctac
     9481 aatgatgaag taatcttaat agatgaaata gcatctggaa atatgcgtgt ttataaagat
     9541 ggtgtaatag ttgaccctat ggatttaact gctcttttat tagataaata gtatatacat
     9601 ataatttaca aatataataa acttataaat aagataagct atgaagtaaa gactttttaa
     9661 atgttgatta tttttaaaca ttttctcgcc tttaatttca tagcttattt aaattaatat
     9721 actctaatta gtagataata gctttaaccc tacaattccc accacaataa aacctataca
     9781 tgcaattctt gatatactaa taggctcatt taaaatagcc atgcctacaa tagctgtacc
     9841 gacggtacca attccagtcc atattgcata tgaagttcca agtggaagat gttttagtgc
     9901 taatgacaaa aaataaaaac ttacaatcat tccaacaaca gtaagtatac ttggagttaa
     9961 tttagaaaat ccatgtgaat tttttagttg aaaagcccaa aacacttcaa acaaacctgc
    10021 aacaaacaaa aataaccatt tcataaattc atccctcttt tcaaatatgt ctcttatttt
    10081 tccaataaaa taacctgaga aatattataa aatatctccc aggtttttgt ccttccgtgt
    10141 tcacaacaaa aactatgttg tgggttttat ctcggaccag accaatcatt aataattgcg
    10201 gaaccctata aaactctatt aattattcta ttttatctat aataatacta tcaacatata
    10261 taaaaaaagt caatatatgg gttccatata taataaaaat aacttttata taccttttaa
    10321 tattcttatt cacttctctc catacccatt tgggtcaatc taagaatatc taatttttat
    10381 ttaatatgtt ataataacat aaaaatattg aaaggagtaa tttctatgaa tttctataaa
    10441 attgcagtat gtcagatgat tactacagaa aataaaattg aaaatatcaa tcatgctgta
    10501 gatatggtaa cagaagctgc catcaatgga gctaaaattg tagttttgcc agaaatgttt
    10561 aactgcccat atgaaaataa atattttcct aaatttgctg aagaatatcc aggtgaaaca
    10621 acaacgatat taagtaaatt agctgagaaa catggaattt atctagtttc tggtagtatt
    10681 cctgagttag aagatggaaa aatctataat acttgctatg tatttgataa aaatggagct
    10741 ctaattggaa aacatcgtaa aatgcactta tttgacattg aagttacagg aaaagttagt
    10801 tttaaagaat cagatactct tacagctgga aatgatgtca ctgtaataga taccgaatat
    10861 ggaaaagttg gtatagctat ttgctatgat attcgtttcc ctgagttatc acgtttaatg
    10921 gctcttaaag gtgctgaaat cgttatctta cctgctgcat ttaatatgac tactggtccc
    10981 gcccattggg agttatctat aagaatgcgt gctttagata atcagatatt ctatgttggt
    11041 gctgcacctg ctagaaatat gaatgcttct tatatagctt ttggaaattc aagaatttca
    11101 gacccttggg gaagaataat tgctcaagct gatgaaaaag aatgtattat ttatgctgac
    11161 attgatagag atttaattcc tgacataaga caacagttac cacttcttaa gcacagaaga
    11221 actgatttat atgaacttaa tactttgaaa taaaacagaa cataacccca taaatcataa
    11281 attaagtgtt aaaaaaattt atggggttct cattaatttg atttaaaatt aatttcataa
    11341 aaataatgct aatattaatt taattaaata atactaataa ttactaatga ttatgctaat
    11401 tatcagcatt tactaattta atcactatta gttatttctt ttattaaata tctttacttt
    11461 tttacttatt atgtcttcta gctttacatt tggattatgg tatttctttc tatttttagt
    11521 cacatctttc tattgaatta cttgcttaaa acaccaatgc acacatgcca gataatgttc
    11581 acaattattt agaaatcttg ctctaccttc ttcaatgttg atattatctc tcctagttga
    11641 tattatcttt cctaaaattt cttttaatta aaaaacaaca ttagttgata tatcaagtat
    11701 attttaagca actgaaaaaa acaataataa ttgatatatc aactaattaa tgtagattaa
    11761 ttcattttta taatttatat actttttaat taatctacct tatttaatta aaatccttcc
    11821 tttctattta tccattttca acttaaatta taagatttca tcagctatat ttttgcatac
    11881 caataattat taaatatcaa atatatattc tattaaaatt tctaataatt tcatccttga
    11941 tttatttaat atataaaaat atactaactt taatgattaa gttttgaaat ataactaaga
    12001 atttgataat ttattgagat ttttatacta aaatatacat actatacaaa cttaatttag
    12061 aagggagcat tcttatgaac aataaaatac tcgtcgtaga tgatgaggaa ggtataataa
    12121 cactcttaaa agattacttt gaaatgaatg gttatgaggt ttacactgct caaagtggaa
    12181 aagacgcatt aaaaaaaata tctaaaaatc cagatatcat tctacttgat ataaacatgc
    12241 ctgaaataga tggaattgaa gtttgtaata gaattagaga ttatgtatca tgccctattc
    12301 tatttcttac agctagaatt gaaaatactg acaagataaa tggttttcgt gctggtgctg
    12361 atgattatat tgtaaaacct tttgatttag acgaacttgg agctagagta tctgcccatt
    12421 taagacgtga acaaaggaag tcaaatcaaa ctaaaattaa attttataat gatttaacaa
    12481 tagattacga aaaaaggtta atttgtatat ataataatca gatttcactt tcaaaaaagg
    12541 aatttgatat agtagagctt ctctctatga atcctggaca agtatttgat aaagaaaaaa
    12601 tatatgatag agtctgggga tacaatagca atggaaatag tgatgttata atggaacaca
    12661 ttagaaaaat acgaatcaaa ctatcaaaac atactcttga aaattatata gaaacagtct
    12721 ggggagttgg ttataaatgg ataaaataaa taatatgtca ttaaaaaaag ctttctttgt
    12781 tcttacttta tcttcactaa ttatagcatc agtgcttact actttcgcat acattttact
    12841 taataatcta tataattcta tacaagataa gtatttaaaa acacctataa atacaggtat
    12901 tataaccata gttcaaaaca atgtgaacca atttagtgat tatgataaaa cattacttaa
    12961 tataatcaac atacttcagc ttgtacttcc acttatcttt tttataggac ttttattatt
    13021 agctgatata attttttaca aggtaaaatt aaaaacaccc atagaaatac tcaataaagg
    13081 tgcaatggaa atatccaaca acaatttaga cttttgctta gaatataata ataatgatga
    13141 attaggtaat ctatgtaatg cttttgaaaa aatgaggtct gaactaaata aaaacaacat
    13201 aaagatgtgg actatgatta atgatagaaa acaacttaat gctgcttttt ctcatgattt
    13261 aagaaatccc ctaacagttc taaaaggtta ctcaaactat ttaacaaaat acataccaac
    13321 aggtaagctt agtgatgaga agattttatc aaccacacaa cttatgtctg agcatattaa
    13381 cagaattgaa tactatgtag aaaatatgag taatgctcaa cgattagaag atttagttgt
    13441 ttcaaaatct atgtcgaata taaacaagtt tatagaaaac ttagatgaaa atatatctat
    13501 cattgctaaa caagaaggaa aatcttttac acttaaaagt caaataaata atataaatct
    13561 attttttgat gaaaatatca ttcttagagt cgtcgaaaat ataatatcga atgcttttag
    13621 atatgctaga aataatgtat ccatacttat atatcttgaa caagaactcc ttacctttgt
    13681 aattgaagat gatggtatag gatttagtaa ggaatctcta aaattagctt taagaccttt
    13741 ctatagagat aagactttaa atgacagcaa tgcacacttt ggtatgggtc tttatatctc
    13801 aaaaatatta tgcgaaaaac atggtggctc tatttctatt gaaaataatt ctactaacag
    13861 tgctaaaatt actgctaaat tctcaacaag aaattaaaat gattttgtaa gctttcactg
    13921 ttcttatata aaatttgtta gtttagaatt tataaaatgt atttcaattt acaaccaata
    13981 tatatactat tttgtagaag ttgtaagagt tgcttcaatt ataatatttg gcaaaaggca
    14041 tttgaaataa taatagaaat atatatttaa atatgtagaa tagtatgaaa ttagaatttt
    14101 ggaggtgatt atattaaaag ttttgctaat aatattacat tctctcgtat tgtgtttgca
    14161 ttgctaatgc ttagttctac attctcttca ctgcctttct ggatatgtta tttttggtgt
    14221 ggaattagtg atatacttga tggtcttatt gcccgaaagt tgagacaaca aagtggaata
    14281 ggtgcaaagt tagatagtat tgctgatttc atttttgcgg ttacaatttt ggttactgtc
    14341 ggaaaaaata ttgctcttcc catgtatcta tggtggtgta ttgttgcaat agcattgtta
    14401 cggttgatta gttacagtat tggttttttt aagtatcgca cattttcatc gcttcatact
    14461 ttgatgaata aaatcactgg aatttctatc tttgcttttc cattactcta tatttgcttt
    14521 ggtcttgatg ttgcaggaat tatgatatgt atcgtggctt ttctttcttc ttttgaagaa
    14581 atagcaatta tgataaaatc aaaagaatta aatcgtgata taaaaagtat atttatgtga
    14641 caacttagaa tttgtgacaa aaataattta tataataatg aggaagtaaa acataaaaaa
    14701 ttatccacaa gtttatgtgt aaaatagttt taaagcaata gagttgtatt gtaaagcctt
    14761 tagtgcataa attacatttt aaattaaaaa tgatactgaa actgcttatc agcactgcga
    14821 attatccgca aatagtgaag actttttaga tttaagctaa aagttgggaa aaaattgagt
    14881 tttaaaactt acactcttct tatatagaaa aggagagtgt tttttatgat tataaaagca
    14941 aaacaattat caaaaatata tggttctaat aacaataaag ttatagcact taataatgta
    15001 aatttagaaa taaactcagg tgaatttgtt tctgtaattg gaccttctgg aagtggaaaa
    15061 agcacacttt tgcatatttt aagtggatta gataatccta cctctggaca agtgttactt
    15121 gatgataaag atatatataa acacactgaa aaagaactat ctgcacttag aagaaaatcc
    15181 tttggattcg tctttcaaca atttaatctt ttacctgttc ttacagcatc tgaaaatatt
    15241 tcaatgcctg tacttctaga taaaaaacaa cctgataaag actatttaaa tgaaatttca
    15301 tcattacttg gaattgcaga tagactcaat catcttcccc atgaactttc aggcggtcag
    15361 caacaaagag ttgcaattgc tagagcactt attgcaaaac cagatataat atttgctgat
    15421 gagcctacag gaaacttgga cagtaaaagt ggcagtgaag ttatgaatct tcttataaaa
    15481 acttcaaaac agtttggaaa gactttagtg gtaattactc atgatgatag aattgcaaaa
    15541 cttgctgata gaaaaatttc aattattgat ggtgttctta tggaggtgaa atagaaatga
    15601 agaattacct ttcactttca ataaaagaat taaaaagcca gaaatttatg actacattca
    15661 tcattatagc aatagtacta tcaactatta tgacaactgt ggttggacag tcaattggta
    15721 tcctacaaaa tttaagaatt gaacaagccc gttcttttaa tggtgataga catgtatcct
    15781 ttcaccaact cactaaaaat caagttgatg acataaagaa agatgataga gtttatcaag
    15841 ctggtacttc aataactatt ggcagtagta aaataaagga ttctggtatc tctgtacttg
    15901 taaaagagta tgataaaaca ggactttcta actacccaaa attaatgaaa ttaaaatctg
    15961 gacatttgcc taaagataaa aacgaaatag ccttagatga aaacacacta aagcttatgg
    16021 gtataaaacc aagactagga gtgactatac ctatgaattt agatatttca cttttaaatg
    16081 ataccatacc accatataat tacacagcta actttaaatt gagtggcatt ttagaggatg
    16141 attatacagg atatgtaagt ggtatagtaa atggtattgt aggtaaaggt acatcagaaa
    16201 atctattacc taagagatat attttatcct ctttggattt taaaataaaa cagcaagaaa
    16261 agtttcaaga aatagtaaat caattagcta aaaaaataaa tctttctcac aattcaattc
    16321 aatataattg gatttactta aatgctctta agatacagtt tgaaaaagat gaaaatagtt
    16381 ctaatagtga tggtatatct atgattatat tggtatcttt atttgttgcc ttattggttt
    16441 tactggcttc tggacttgta atttataata ttttaaaaat ctctgttaca aagaaaatta
    16501 aagagtatgg atgtttaaga gcaataggag ctgaaccaaa ccagatatat aagatagtta
    16561 ttttacaaat cttaatttta tgtactgttg ccatacctat tggagctgta attggaatta
    16621 tatcttctaa aggcataact ggaatggtca ctaatatctt aaatccagat atacttctag
    16681 caaatgataa taaagaaatt actgagctta tacataaaaa tacaacagca tatatattcc
    16741 cattagtatt aagcactaat gtatctttga ttttttcatt tatttcagca ttaccatcag
    16801 caatatatgc ttcacatgtc tctcccaaaa ttgctatggt tggtagtact accaaaatca
    16861 aaagaaaaat taaaagagaa aaaacaataa aaaactttga aagacatcta gcatggctaa
    16921 acttaaaaag aaataaagga agaactataa taactatact atcattattt atgagtataa
    16981 cagtattcgt tgcactgagt gagttctcta atgtattaga tgtatctagg tcagtaagta
    17041 atttaaaaga aggagatttt tccttaacaa atgaaatatc tggttttgat aaatcaacac
    17101 tagataaaat agctaaaatg aaaaacgtca atcgcacttc ctttataaag tactctgaat
    17161 acaaacaggg tgaaatagat acagatataa attttgaaaa tagtggtgag atgttaaaaa
    17221 tcattggaat tgatgagcaa actttaaaag acttaatgcc ttctattaca gattctatac
    17281 tagaagactt taaaaatggt tctatctgtt ttataaaaaa tccgattgct atttctacac
    17341 caggtgtaaa aactagatat acaaatttaa aacctaaaga tagtatcaca atcaacaaaa
    17401 aacaactaga tatatatagt acagtagata aaatgttctt tttacaaggc aatggctgga
    17461 taaatggtgt tgatgttatt gtatatgatt ctgtttataa cactttgaca aataaaaaca
    17521 agttcaacca gataaatatt tatgctaaag ataaatcaaa attagaacaa ataagattgt
    17581 ctattgaaca gatttgtgaa aataatcctg gctctcattg gatatcatat attgaatcag
    17641 ataaacaact taaagagagt tttaaacaaa tagaatttct agcatgggca gttatattat
    17701 ttgtgggatt gattggtact ttaaacatca ttaacacaac tcatacaaat ataaatacta
    17761 ggactaatga gattggagtt aaaagagcta ttggtatgag taataggagc ttatataaaa
    17821 tgtttttatg ggaaggtgtt tattatggaa tttttgctgc tatatttggt tcaattgctg
    17881 ggtatgccag tgctattatc ataaacatgg caactataga aaagcttgat ttcactaata
    17941 taccaattac ttcaatttta caagctacta ttatttctgt acttgcatgt attatagcta
    18001 ctcttattcc gttaagaaaa gttaaaaaga tgaatataat tgactgtata gatatcaatt
    18061 tataactatt ttacagataa taatataaat taaattatca atgactgtct ctattttctt
    18121 tcaaatctaa ctaataaatc tttttaacta taatataagc tttaaaaaag gcctgtctca
    18181 aaatagagat aagccttttt tcattgtcga aataatgaaa atatatttaa cttcacaaaa
    18241 aaagagtgcc tcacgaatta aaaatttcgc tttgagacac tctcctttaa tttaaaatat
    18301 atagttaaat gctatgccaa aatttcacac atgctccacc tgattttgaa ttttctattt
    18361 taacagaacc tccaagctgt tccactaatt gtttgacaat gtaaagccca agaccagaat
    18421 gtccaccttt tgtctgccta gcttcatctc ctcgataaaa tttatcaaga gcctttttta
    18481 aatctttaga gctaaaccct ctaccagaat cacaaatctc ataagaaata caattttttt
    18541 catcctttac agtaatacta atattaccac ctgatggagt gtattgcaga ctgttggata
    18601 tgatattatc aaaaattcgt gtcaacctat caacgtcgat ttgaattggg gattgtatat
    18661 tcccctgcat tttcaatata agttcaactt ccttttgatg agcctgtaat tcatagtctt
    18721 gcaccttttg cctcaaaaat tcaggtaaat ttataggaac aagatttaat tgtatatttg
    18781 acttttctaa gtcagacgta tattgcatct tttggacaag agcagcactt ttttctgtat
    18841 tttctcttat cactgtaaga tacctatgaa gtttttcatt gtcatctgta ttattaccaa
    18901 taagtgcatc tgtatatccc aaaataatag aaagaggaga ttttaaatca tgtgctagag
    18961 cttccaccat ttcaacacgt tcctgctcca tcttccactg tgcagataaa gagcctttta
    19021 attcgtcttt catttcagaa aaggcactac aaagtttacc gagttcatta tctgaataat
    19081 agtcgatttc aaaatcaagg tccttttctt ttatcttctt ggacgcatca atcaatagat
    19141 gtaatggttg attgatattc tttacaaagc gcttagaaag ccatctagta aaacccacga
    19201 tatatagaaa tggagaaaac aaagccatta taataactgc aaatacaaat ctccctctaa
    19261 tatttgcaaa ggtgattttc acttggtaga atagaataac agcaccctca atctttccat
    19321 tatccccttt gattggaaca gtatggatat aaccaccttt acgaacagtt ttattgataa
    19381 aattattaaa taattcttct tttgttttaa atagtttttt ggggttagta ccatataaaa
    19441 tattgccatt attatccaca acttgatata gcatatcatc cccacgaatc gttcttttta
    19501 aaccttcttc attcgattgt gataacaaag ctatgttttt ttcattgatg tatttttcaa
    19561 ttctaggaac ttgtcgctca taatagtttg gtggatagat atccttattt aaggaatgaa
    19621 tatacaaata gagagcaaat acataagtaa tcactgtggc aactatactg gctattataa
    19681 taaaaataaa agtatgtcta aattgggtaa taagggattg atttttcatt taataacctc
    19741 tctctcttta cattttattc cacttatacc caatacccca aactgtggaa atatattctt
    19801 tttctggtgt cacagcagaa aacttagctc gtattttttt tactcgttca acaacagttg
    19861 aggaatcacc ttcagaatca cacccccata ctttttcata gatttgttct cttgagaaaa
    19921 cttgtcctgc atggagtgct agtaattcaa caatatcata ctctattttt gttaaatcaa
    19981 tattcttacc atcaatttta attgcacgtt ccttcatata taagcataac ttcccaaaat
    20041 acaaagtaga tctcttgttc tcttcattga tatactgtga acgcttttcc ctacgcagat
    20101 tagcttcaat ccttgccata agttcacgca gtccaaatgg ctttgttaca taatcatccc
    20161 ctccaaaggt caaccctttg attttgtcgg tttctgattg ctttgcactt aaaaatataa
    20221 ttgggcataa aacatcatct ctaattgcct gacatacctc aaatccattc attttaggca
    20281 tcataatatc cagtataata aggtcaggct cctgttttga taactctata cctgcctgac
    20341 catcataagc tatcaacact tcatgtcctt ttgccttcaa ttcatcctca agtagcatta
    20401 ctaggtccat ttcatcatca ataatcaata ttttactcaa tataacacca cctttctctt
    20461 atgggaaggt cagtattaaa acaatattcg tctactcata acttttcctt ccctcccaca
    20521 ttttaaacca aataacgcct cctatcaaga atataatcaa acctattgct actactataa
    20581 gctctatact agctgtttgc atcactttag agtaaaatgc ctcagttgaa atagttccag
    20641 cttctttaat aaaataaatt cctggaagca tacctagttt tactggccat gtccatggaa
    20701 caaatgccca tactttttca ccaacgctag ttaatccaag tattgctgcc atcaaaattc
    20761 caccaatact aataccaata gatgcaccca taccccatgc aaaactcacc caaagatgaa
    20821 tagctaatag tggaagtgtc ccaatcacca caagtcctgc tgctgacagg aataaccata
    20881 ttgttgctcc agatggcact gcaatactca ttcctatgca aagtatcaac gtagcaataa
    20941 atgtgcatat agttaggcaa aacagaagaa aaagaaattt tcccagatat aatctgacac
    21001 gagaaatacc tacacataaa aaaccattaa aatttccagc aagctcttcc tcctgcacta
    21061 taaatcctgc taaaatacct actccaatag gaatgatgaa tacagtccat actgtaaaaa
    21121 atccttcaaa agcaaattct tgtgtacttc cagatttagt tgtgagataa aaaaccacac
    21181 ataatgaaaa aataataggc atacaaagag taagccactg gacagctgtc ctctttgctc
    21241 gaagccattc tgatgataat agttttatca tttgtcatcc ctcctattga accaagctgc
    21301 agtaagtgct gttaatacta taaacacaac caaagaaaca acaatcccaa taggaatcac
    21361 tgaagtattc aaaagtgggt ctccagcttc taatatagta ccgttaggat gtatgttgat
    21421 gattgggcat accattctaa ctgcccaact ccaaggtact gcaatccaaa atggttttgt
    21481 cgcagcaaga acaccaaata tcatacctaa agctccaact cccatactta ggaacatacc
    21541 tttccatgta gctagccata gctgaagtgg aagtatagca agagaaacaa cccagcatac
    21601 aatacttgcc cctataatct gtccaaaagg aactggacca gctttcaata ttaaaccagt
    21661 tataattgtt acgactatta aaactagcgt tgaaataaaa ctgtagactg ccatagctat
    21721 aactttatta atccaaagtg tcataggaga cacattgtgt gtacgtaaag cacgataatt
    21781 tccagctttt ttttcctgga aagctaccaa agtagcgaac aatgcaaatc caataggcag
    21841 aaataaaaat gaccaccagt taaaaattaa tgctaaaaga ttttgccacg cccaagaagt
    21901 tgtttgagat aatggatttt gcatgagtgt tgattgcatt ataaatgcat atgctgcaaa
    21961 agacactggg aaaaaaacaa taagtttacc cataaatgtt cttttatact ttaaaagttc
    22021 tgattgtaaa gcattcatct gttttgtcct cctttaagaa taacatctgt aaaaaattct
    22081 tctagatttt cattagggtc aggcattcct tgaaataata gtcgtcctcc atttataatt
    22141 cctatattat ctacaacttg agcaacctct gatagaatat ggctagaaag aattacagtt
    22201 ataccttttt tgggaaaaga agcaatcaat tcacgcaatt cttgaatgcc aaaggggtca
    22261 agaccattgg ttggttcatc tagtattaac aactctgggt cactcaaaag tgcaatagct
    22321 attcctaacc tttgtttcat acccatagaa aattgtgaag ctctcttttt acctgtattt
    22381 ttcaaattta ctatttccaa cacttcataa attttatctt taggtattcc caatattttt
    22441 gtatgtacta acaaattttc ctctgctgta aggtttccat acaatgcagg ggattctatt
    22501 aaagaaccta tttttgcaag agattctcgt ttccaaggct ttctatcaaa aataatacga
    22561 ccatttgttg ggcgaagaag accaacaagc attttaagtg ttgtggactt tcctgctcca
    22621 tttggtccta aaagtccata tatactattt cgttcaattt gtagagaaac attgttaact
    22681 gccatttgtt ctccatatct ttttgataag ttttttgttt caagaattaa atctttcata
    22741 ttaatttctc ccttcttgta ataccttaaa tctgttacta agagaatact aacatgaaaa
    22801 aataacaatt ctataacacc tactaatttt aataaaattt aaaataaaaa atagagttac
    22861 caattttatt ttggcaactc tatttaagtt tatgttttac agttatatta gatttaaact
    22921 tagtttcatt atcacactaa cttcaaattt actctataat ctttaaatca aacactaatt
    22981 tattaatcaa acactaatct attaatttat atttctttag acatctaata tagtttgcta
    23041 ctaaataata attatttata tcatatttat ctaatccttt aaaagaagtt atttcatcat
    23101 taagctcatc actaccttct acaaaaacac aacctgtttc aaattccata cctacaataa
    23161 tcttacagtc actataaatt tcctcttgag tatcgtacaa tttttttgca tttccttcat
    23221 ttggaattgt aaatacaata ggttttaatt ctttatcact ggaaatcttt tgtgaaaaag
    23281 gcttgtttaa cttaatatta ttgataacta catgtttaaa ttcctctgaa gtttcttcta
    23341 ctattacata ttttcgcttt aaaaactcta ttatttctaa aacagactta gaatttactt
    23401 ttaaaatact tttatatttt tcatataaag atttccactg ttcaattttt tcctgtggta
    23461 tttcttggat atgtgtactt attttttctt gagatatttt tttcaattaa actctccttt
    23521 caatacttaa atatccttat gaatctcaca tgactaaagt tacaaggttt ctacttaata
    23581 gaattttgca tacttaaata tgtcttatta attctctaca ggatatctcc gtagttccta
    23641 cgattcttac ataagttact tattttaaat tgttattagt tatattctaa aaattattta
    23701 ttttatcact aatataatac tcttaaaaac tttacaaatc aatttaaatt tgctaccttt
    23761 tatttataac aacttatagt acatttctcc tatgcttttc aatatattac ttttaaaagg
    23821 aggttttcat tatgatttta aatagagctg agcttttccg aggatattct ttaaatagat
    23881 ttaacgagat atgcaatata ttatcagtaa ataaaattaa atataagtat aaagtgaaaa
    23941 ataatgctta ctctaaaaaa ccttttttta atgaaataac acttggcaat ttaggccaaa
    24001 aggaagattt ctcttatgag tacttaattt atgttcataa agacgattat gaacaggcag
    24061 agtctctaat aaattctaag ttgcgataga ttatctataa aacatgacat tctgttgtca
    24121 tgttttatat gttattatac tttcaaatat gctactatat tttcaaaatt gtgtgcttta
    24181 aaactagctt tttttagtaa tttaaagctt aaaactaagg agactcgtta tatgaaaata
    24241 aatataaaat caaagttaag tgaatttatt aaacagaaca atctttttga tgacagcaga
    24301 ataatatcct atcttcctaa tataacaata gaaacagaca aaataaaaac tataatgatt
    24361 aatgaggttg tcccaactaa caccaatgac gatttttata gtgtagataa agatgctgat
    24421 tatttaaaaa ctactattcc tttatttgac agtgcaggaa taaaagtatc taacataaat
    24481 gatatcctag atatgggtat ctatataact aatgcagtaa aacttcctaa atcagaatat
    24541 acaataactc gtgatacaat taaattacat atgcctattt tagaagaaga aattaaatta
    24601 tttaaaaacc tagaggtagt aatgttaatg ggagatgttg caaaaaaatc ttttaatatg
    24661 attactaaaa agcatataaa aaagaatgtc atcccttcca tttcaacata taaacttcgt
    24721 aataatgaac tttattatga taatttaaga gtatttccat catatattat gactggtgga
    24781 aacatactga ttgaaaaatc aaaatttgaa atggcatcag aagatataaa aaaaatgttc
    24841 gagattataa acggttgata ttacaaaata ataaaaacta atataaaata aaaagtgcct
    24901 caaaaacttc tatttatgag gcacttttat tttatattag tgtaactata tactattaac
    24961 ataatttatt atttatattg ttctttttaa tctctattcc atttagtcta ggtaacatta
    25021 ctctttacaa gattacttta tatttctttt atatctctaa cgtttttatt taataaaaca
    25081 attattaata caagtcaaat atatctattt atctaaaaat atatctttta cagtaatatc
    25141 tggatggtga tacttcttcc tattcgttaa aaaagatttt tttacattaa tagcctcttt
    25201 tggacaccag tgaaaacaag ctaggcatct ttcacactca ttaccccact ttggcttttt
    25261 atcaactata cttatattct ctacaggaca aaccctttta catgtcccac atccattaca
    25321 tttattttct gcaaaaaatt tagtagttgc aatttgcata ttcttaccta ctaaacgaag
    25381 tacaacacta tctatatgtg actttaaatt gttttttcct tctatatttc caatctccaa
    25441 gttattgata cattttgcaa tctcagctac cctattagtc tgatttttca atctttcttc
    25501 ttcaacatct ggaggtgtta tcaaagcatt tccaggcata ttgattaaaa aaccagcaga
    25561 taattttttc cccctttttt taagtaactt atctatagta aataaactat gtccagctac
    25621 cccattacaa gtggcaatgg catatatatg agtattaata ttaaaattta atttctctac
    25681 aaaagacttt actatatcag gaacatcagc aaaataaaca ggaaaaacaa ttaccaatat
    25741 atcttcattt atgtctatat tattttcttt tctatgtata gctaagggta taacttcttt
    25801 acttccattt aacgtttctt ttaaaatatt tgaaactact agcgaatttc ctgttccaga
    25861 aaaataataa atcttactat tcattcttat ccctctttct atatttctac atcatcaata
    25921 gttaaaaagt ctcttaaaat aggatttata tttactttcc aattctatcc aaaatatcag
    25981 taaacaaagg caattcttca tcagagatag atttaaatgt ctctgttgca tatatacttg
    26041 caatttcatt taatggttct tctaattctc tacctaaatc tgttaggaat atttgaaact
    26101 tacgtctatc tttaacatct actttacgga caattaatcc cttatttttc ataacatcta
    26161 aaattcttgt tgtattagat ttatccttac atgatttttc acataaatct atctgagaaa
    26221 tcccatcttg ctcccataga aaccttaata acgcataatg gtcagttgtt atatcatatc
    26281 cattttgttt aaacatcttt tttaaatcat cttttacttt taacgaagta cttactaact
    26341 tagttgtagc ttcatatagt ttctcaaaat ctttcatttt acctccattt aaataatccc
    26401 ttgctcctcc catctatcaa ttattccctt atattgctca atatctttaa aagccattgg
    26461 ctttaaaaca gcatttatag caataaaatt atagatttga gaaagcacag gtggattttt
    26521 cttttcctct atgcaataaa taaatttttt agataccttt tgtatctttg attctacttt
    26581 ttcagttata ggattttgat taaatccagt ttttatagat aaactaccac aaacataacc
    26641 tcccgaatct aagaccatgg attttataaa agaaattgct tttgaaccac gtgcattttc
    26701 atatgtagta actgctatac atggcttacg atacaataat ctttcaagca tcatatgtgc
    26761 tctatctgta aacaccttga aaagtccagt tacactactt ccataagttg ggctaccaaa
    26821 tataacacca tcactcttag taattatatc atgaatatac tctactttat cattttgatt
    26881 gatacacttg cccattttat aacaatttaa acaaccaata caatatgatg gatttacctc
    26941 acttaaatca aaataattaa tttttacatc tggtattaat ctttctatat ctttatacaa
    27001 gtaagttaaa acttttgatg tagctccatt ttttctaggg cttccattta taactgtaat
    27061 tatcatttct atatctcctt tttagttgtt atatcaacaa taagtatatc aactataatt
    27121 ttagctgtca atataaacca tttatttaaa gctatactta cacagcttaa ataaaagttt
    27181 tatttaacta catgtgctta tttaatcaac tataaatgaa ttatttttaa taattgacaa
    27241 actaaattaa tgataatata ctttatgtat tacaaatgta agtagaagga ggtatagtat
    27301 gaaaaagtta ccacatattt cagaagcaga atatcaagtt atgaaaatta tttggaaata
    27361 tgctcctatc agcactactg aagtaattga aaagttggta gaaacaagta catggagtcc
    27421 taaaacaatt caaacaatgt tattgagatt agttaaaaaa ggagctttaa catatgaaaa
    27481 aaatagcaga gtattcgttt atactccact tgttaaagaa gaagaatacg tagctacaga
    27541 aagtagttct tttttaaatc gtttttataa tggtactctt aattctatgg tactaaactt
    27601 tttagaaaat gataaactat ctgaagatga tattgaggaa ctgagagaaa tcttaaataa
    27661 aaggacgact aagggggata aataaatatg tatgccccat tctttatacg atttttactc
    27721 agtacattaa ccttatcaat attaattgct gtaattttac ttgccaaaaa agtatttaaa
    27781 aaacatattt ctgcaaagta ccaatacaat attggattta tattgcttat aatgttaata
    27841 attccatttg tccctcttaa atatattaat cttggaaatg tatttaacta tttatatact
    27901 tttaatcaac ttggaagcag tactaatagg acttctatga taaaaaatag tccaaattct
    27961 ataattaata actcaaatgc attaaacgat ttttcagtat ccctaaacca agttaatttt
    28021 gatagtttaa atattttatt actaatatca tggataattg gaattttaat catgatagct
    28081 attactattc attgcaacat taaaataaaa aatatgaaaa aatcaataca aattttaaga
    28141 gatgaggaga tagtatttat atttgaaaag tgtaaaaaag atattggtat aaataaggat
    28201 tttatactat gcaaatcacc tattataaat acacctatta catttggata ctttaaacca
    28261 cacattatat taccagataa gtctatatct aaattatctt taaaagatat aaaatatatc
    28321 ttacttcatg aattacaaca ctttaaaaat aaagatatac tgataaatta tataatgtgc
    28381 ttccttcaaa tattatattg gtttaatcct cttgtatggt atgcatttaa agaaatgcgt
    28441 atagaccgtg aaattgcatg tgatatttca gttttaaaaa agcttgataa agatagtcat
    28501 atagaatatg gacaaactct aataaacttt gtggataata tttcaagacc atcaaatctt
    28561 acacttacat cagatattgg tgggtcaaaa aaacaaataa aaaagcgact attgaagata
    28621 atggattttc ataatgaatc aaatacgtta aaattcaaaa gcattttaat ttttacattg
    28681 atagctttaa ttgtatttgg aaatattccc aaactatcta ttatggcaga tatcaatgaa
    28741 aaatatagac ctacaaatga acaaactgtg tacgaggact taagtcagta ttttaaaggt
    28801 tttgatggaa gttttgttat gtatgattta aaatccaagc aatatcatat ttacaataaa
    28861 gaaaaaagta aaacaagaat ttctccaaat tctacttata agatttatag tgccttattg
    28921 ggattggaaa atgggataat aacaagaaat aattcacata tcccttggga tggaaagcat
    28981 cattctaata gttcttggaa tgaagaccaa gacttatttt ctgctatgga aaactccgta
    29041 aactggtact ttcagactct agataaaaaa acagggctaa aaaacataca aacttatctt
    29101 aggcaaattg gatatggcaa ttatgatgtt tcaggtggta tctcaaactt ttggctagaa
    29161 tcttcattaa aaatatcacc tattgaacag gtagaattac ttgaaagttt ttatacaaat
    29221 aagtttaaat ttgaagataa aaatatagaa acagtaaaag attcattgtt aatatcaaaa
    29281 aaggatgggg tatcactttt tggtaaaaca ggcactgcca atataaatgg aaaagatgta
    29341 aatggttggt ttataggtta tgtggaaaaa aatgaaaata cttatttctt tgctacaaat
    29401 attcaaagca aagattattc taatggtagt tcagcatcta agataacatt atccatatta
    29461 aatgacaaaa aaatctataa tccttaatat atttactgta cattctaaaa aattcacata
    29521 attttcatat taattatcaa ttaaattcat atacaaggct tattatataa acatagaaga
    29581 tagtaaaact agcttaaaaa cataatataa taccctatac aaatagtggc aactctccct
    29641 cacatcctca attgttgcca ctatttaatt ttttgtatga agttaaatat attttcatca
    29701 tttcaacaat ttgggtgcaa tacaatctct attttgaaac aacctcttta attgttttag
    29761 agtttatgaa ttatttctca tactttaaaa agattgaatt actcttgata atcttctttt
    29821 gtagtcatta catatcacct actactcaac acatattctt tgacctattt ttacatcctt
    29881 gtttatatcc aaaatattta ccttcttacc atctggaaac aataccattg ttaaagtaga
    29941 ctttcctaat tcatgtattc tctttaaatc aacattaaca agaacatctc cctgtttaac
    30001 catatctcct tgtttaacag caatatcaaa gccatctcca tttaatgcaa ctgtatcaat
    30061 tccaacatga attaatactt ctccattagt tcctttaatc ccaaatgcat gtccacttga
    30121 aaccactgtt tctaatttac ctgaaatagg agaaacaatt tttccatcta taatatcaat
    30181 agcaaaacca tcacctaaca tttttttaga aaatgtttca tctggtacat tttctaatgc
    30241 aacaattttc cccttagctg gagacacaaa gttttcatta ttttcattaa acactaattc
    30301 ttcgtcttca tcttcattta tagcttcttt aggcactcca aataaacatg ttacaataaa
    30361 gcagaatgca accacaaata ttgatgctaa taagtatgtg attaaattat atccatcata
    30421 gatatacatt aaataagaag gtaaaactgc taatccatat gaattagatt gaatatgtaa
    30481 aattgataat attgctgctc ctaaacctga agatgcacac ataataatca aaggctttaa
    30541 attatatcga agctgaatcc caaataaaac aggctcactt ataccaaaaa gttgagatag
    30601 cattgctcca actgcagttt gtttaacttg attattttta gattttttca taaatgctag
    30661 acatgttcca atattcgcaa atccatacat tgcacaaaga gtaataaggg cattaaatcc
    30721 tgtatttgct aatagtgatg tttcaatcat tacataagta tgatgtaagc cagtaataac
    30781 agctaatgga tatgtaaatc caataataaa tcctccaatt cctaaaggca aatcaatcaa
    30841 taagctgatg atatcaacca tttttaattc tattgtatgc attatagggc ctacacctaa
    30901 caaaataact aacattgtta ttagcataac aaaaaatggt gtgaaaataa ggtctaatac
    30961 attaggcata tgtttacgga accatttttc aagattagct ccaataaatg ctgtaacaat
    31021 agctgttaaa acacttcctt gacaacctac aataggaata aatccaaatg ccataattgc
    31081 ttcaatttca tttgatgggt cagcaacaga atatgcatta ggaagtattg gggaaactaa
    31141 cataagtcca ataacaagtc caataacagg tgttcctcca aatactttaa atgctgacca
    31201 tacaataatt gctggtaaaa aagcaaatgc tgtttctgta agaaccgaaa caagtgtctg
    31261 aatatacaat ggaatatttg cagaagacat tccaaataat ccaagtacat tatcattaaa
    31321 caaacaaccc tttaatccca agaataatcc tgttgctgca ataactggaa taataggaac
    31381 aaatatatct gctagagttc tcataacttt cttaaatcca gtttcattat ttttaactaa
    31441 ttcatcttgt tctttttttg ataaagtttt taatcccatt ttttcaactt ctgcataaac
    31501 tttattaact attcctgttc ctaaaataat ttgatactgt ccagaagtaa agaaaacccc
    31561 tttaacctca tcaacttttt caactttctt atcattaata atttctctat ctttaaccat
    31621 cactcttaat cttgtggcac aatgtgtaat agaaataata ttatcttcac caataatttt
    31681 aataagctca tttgctattt tattatattt attcattttt ctacctcact ttcaataata
    31741 ctgcatgaaa tggtttcaaa cgcactgttt tatttaatag atttatatca tctaaatttt
    31801 ggaatacaat atcatatttt tcttctactc ttatttctac aggtttatca gaaaaattat
    31861 aataacaatc aataactacc aaatctaatt gccttctata cgcaataata tcatcacttt
    31921 ctatatcaat aggttctatt gaaccataaa tcaaacaatc agaatactca ctatcttgtc
    31981 tcaactttat catcttttta taaaattcta aaatactctc tgaattgtta atctgactct
    32041 gtgcattaat atctttataa ttttcaataa cctttaacca tggtgttgta tctgaaaaac
    32101 ctgcattttc tttatctgcc catggaaatg gcgttcttgc attatctcgg cttcttaaat
    32161 tcacaaattc taacgcttct tcttctgagt aaccttcatc tattgaacga tagtattggt
    32221 caatgctaga taaatcatta aaatcattta tggtatctct tttaaaattt gtcattccta
    32281 attcctgtcc ctgataaata aatggggttc ctcttaaaaa gaaatacatt gctcccaaca
    32341 tttttactgc atcatcattc ctttcgtatt gcaaaagata ctttgttgta gctcttggtt
    32401 ggtcatgatt ttcaataaaa ttagctgccc atccatgttc ctgaacatac atttgactat
    32461 ctaaaatgca ttttcttaaa tctggaattg tccatgaaat tcttttaaac cactcactac
    32521 cagaagcaac atctaagtca gcatgtttaa agtcaaagac cattgaaaag aaaccatctt
    32581 ctccaataaa atcacctaac tggtcatagc taatacctgc tgcttcagca acagtcatac
    32641 aatcatattt tttaaacgta ttttctttta attcataaag cattttttct attccaggct
    32701 gatttctaac tgtttttgta catttaacaa gaccatcaac accatcactt tctaaacttt
    32761 gaaaacttaa attctttttg atgaatgtaa tagcatcaac tctaaatcct gccactccca
    32821 tttgagacca ggtattaatc atttggtaaa gttcacttct taatattgga ttttcccaat
    32881 taaggtcagg ttgttttttt ccaaaagaat gaaaataata ttcgtctcta ttctctacct
    32941 tttcccaaac acttccacca aaaacagacc tccagttatt tggcaaatcg tttccttttt
    33001 taaaaatata ataatcatga taaggacttt ctggattttt taatgcttct tgaaaccaag
    33061 gatgttcatc acttgtatga ttaagaacta aatctaatat aattttgatt cctctatctt
    33121 tacttttttt aattaactct tttaaatctt ccatacttcc aaattcactt gcaatatcca
    33181 aataatcact aatatcatac ccattatcat ccataggtga tttaaaaatt ggacataacc
    33241 acaatgatgt aatacctaaa tcttttaaat aatctaaacg agaaataatt ccctgtaaat
    33301 ctccaattcc atcattatta ctatcttgaa agcttcttgg ataaatttga taaacgattt
    33361 ctttttgcca ccatttcttt tccataaatt actccttttt atatgatatt tcttcttttt
    33421 aattctttat aaattccatt atcgaatatg tcctcacata tagatgtcgc tatatcttta
    33481 agttgttgat gactattttt cattgcaatt gtaacgtctg atgcttgaaa catgacaatg
    33541 tcattttgac catcaccaaa acatatggtt tctttttgag ttactcctaa tctttcttgt
    33601 aatctcttaa ttgctttgcc cttatgaaaa tctttttgaa taatttcata atactgacta
    33661 gaaatatctc tctgtgctaa ttccatttta tcttgtagta tatctttcac ttcgtcaaat
    33721 accttttcat ttgaccataa acaaatttta tgtatatctt gtgacttata ctcttcaatg
    33781 ttattttcat atgttatttt ttcttggata tgttgtttat ttatacaaga attagttcct
    33841 ttcaactgat tcattgtttc aaatatttct ttggcttttt gattcatgaa aactttttcc
    33901 tgactctcaa tcgaaaaagc aacttctcta ttttttaata aacaaacaac ttcctttatc
    33961 aatctttgat taaaagattg attataaagt aattcaccat gatattgaat gtaattacct
    34021 cctcctgcaa tatatccatc aactcctaat gataaaacat catcttgtat tgtacccata
    34081 cttcttccag tacaaataac aacactgcaa tgattctttt gacataaacg tatagcatgc
    34141 tttgcagatt ctgggattcc atatacctca tctctaagcg taccatctat atcaagtatt
    34201 aataatttgt acaatttcat cttcctttct tactatcaaa atcataatag cattcaaaaa
    34261 aaaagatatc aatattttga tatcttttaa aaaatatgtt catttttagc acaaattttc
    34321 attttcgggg aatatgttca ctttctaaat acatcttgta tttaatataa agcagttcaa
    34381 ttaaaataaa ataaggtgtt gttacatcgt agtccagttg tttatctaca gaaatagata
    34441 tagattgaat atacaggttt tcatcacata atcttgctaa aggattactt atcatttttg
    34501 taatagaaac catataaatt cctttcattc tcatttcttt agcaaaatca ataattgtag
    34561 atgcatctcc attcaatgaa ataaagaaaa tcatatcatc tgtttttata aaatgattaa
    34621 gtgcctgaat catatcataa ccataaacat catatataat tttccctgtt ggtaagaaaa
    34681 tccttttcat ctctttagca actctttcct gagaataacc ttctccaaag acgattatac
    34741 gatttgcctt tttcattctt tcaaacataa tcgaacaatc cttcttctct atatcattta
    34801 tcaccttatt atagcaatcc attaattggt gtttactttg atttttatat tctacttctg
    34861 tttcatttaa gcgtataata actcttaatt cactatatcc aggtaattgt agtttttgag
    34921 caaaacgaga aagtgcactt gtagatatat ggtatttgtc tgcaaattca tctatagaaa
    34981 gtttaataca atcttcttta tgattaagaa tacactcaca gatatactta tcatttgctg
    35041 taaatgaatt ataatattta ttgaaaagtc cttcaatttt cattcttttc tccttctata
    35101 ctctatgtaa ttcatatgaa gcaaatctaa tagagcataa aatgctccta cgacttcata
    35161 agatatagct tgtaatgtat caagtttttg agtttcaaca tacagattat actcacaaag
    35221 tgttgcaatt gtattattat caagcctagt taaagaaatc gtatgtatat gattgttgat
    35281 aaattttgca atttcaattc ctgcttttgt ttctccagac aaagaaatga taataaataa
    35341 atcacttttt tgaaatgatt ctctcataaa ttcaatttca cctatatcaa ataagtcaat
    35401 aacacattta cctactgaaa gaaatattct ctttatttct tgagctaaac ttttctgttc
    35461 attacctgtc ccataaatat aaattgtttc tgcatcatat attattttac aaatatcttg
    35521 aaatgatatt ttttgtaatt cattcattaa tagtcgataa ttctcgcaaa catcatgaaa
    35581 attattatca ttattaacaa attctagttg attattttta agtaaatact ttaaatcaga
    35641 gaatgaatct aatccaattt ttctacaaag ccttaataaa gtagctctag aaacattaca
    35701 ttcatttgca attttttcac acgaaaaatt acggtattct ctttgacaaa tcaatatttg
    35761 tttaataata attttatcat tttcatttaa attatcataa ttttggttaa ctaacgattc
    35821 taatctcatt ttttccactc cctaaatatt attttaatat acattagttg ctttttctag
    35881 ggaagagttt taaataataa ggataaaata atcatttgat tttattttta ttaaaataaa
    35941 aataacctgc taaaagcagg caccaaaaag tacttatcct ttcgaacatg tactttagat
    36001 attgctttct tcggaagctt catctcttca tactctaaaa tagagttttt tctaactcaa
    36061 aagtattttc catggtagaa attactttaa ttcatctgcc atttattttt tatcttattt
    36121 aataattact actacttgaa tatttacttc tttaagtaaa tttcatagtt aacaaagcta
    36181 aaattattat tatagatgtt aaaatacaaa attgtaagta ttgttataaa tatgcttaca
    36241 gctacaaata tacatgatat attaaaaaga agctgtaaat tattatcata catacaagca
    36301 actacgcctc tattaatcca tgttaatttt tattatttaa tacaaggagt tccatgagac
    36361 atacatatcc attcatattt taaattatcc aattctctta tagatttcat catcttttta
    36421 taatcccaat tccatggatt aggataagga actatatttc cattcttatt tttgactaaa
    36481 tcacctgcaa ataatacatc ttcaaaaatc atgcagacat gccctggagt atgaccagga
    36541 gtatggataa tttttatatt cccaatctgc atattctctc cataaggttc aacatcctta
    36601 atgagccttc tggaaattgc ctttccaata aacttcttaa acccaggtct atccttctct
    36661 cctataataa aaggtatatc ctctacatga gcccatactt ttgctcctgt tttttctttc
    36721 aataatttaa tattagatat atggtcaaca tcatgatgag ttaataaaat atgcttaata
    36781 tctgtaagtt taatgccaag tgtttttaat tctttaatta tatttttccc cataaaagga
    36841 agacctgtgt ctataagaat aatttcttta tcaaacacaa taaaacaatt tgagccacga
    36901 gtactatcta acattaatac attttctttt atcttcataa ataaattccc cttatttggt
    36961 attttaccta tataattaat taataaagtt ataaatagtt ataatacttg atattaattt
    37021 tattttttat taaagtatac tataggtata caaatattat atttacataa atataccatc
    37081 agtatacttt tttatcaata gaaaggaata atttatatgt cagaattatc aaaaagagat
    37141 aaagaaaaaa tacaaagaga aaatgagatt attgataagg cagaaaaatt attttgtctt
    37201 aatggatttg ataatacaac tatgaatgaa ttagcaaaag aagttgaata tactaaacgc
    37261 accatataca agtacttttc atgtaaagaa gatttattct ttgctgttgt cttaagagga
    37321 tataaaagac tttgggataa tgttaaaata gaaagtgcaa aaggcaaaac agggtttgaa
    37381 aaaataaaac tttcatactt tgcttttcat aaattttact ctgtagaacc ttctctatta
    37441 tgccttatgg gaatgattgg tattgtaaac tctgaaaaat cggatactga tatgctgttt
    37501 aaagaaaagt ttttttcttt taataaattt atgtttgatg aaatacaagg aatgtttgaa
    37561 attggaaaaa atgatagaag tattaggcat gatattgaaa tacctactct tatgtattca
    37621 tcaatattta cacttacagg attttttaat ttactatctg taacaggaaa atcatacctg
    37681 aacaacttta atatagatga ggaaaaattt attgaaacaa ctcttgctct tttaatagat
    37741 tcaattaaag cataaaccta agtttataaa ttaaagttta tatacttaaa tgataatttt
    37801 ttctatctct aatatgaaaa atattaaaca taaaactaat aacttagtta atggaataac
    37861 taaattactg aaaggattaa aagtaaatgg ctaaaatact tcttttagaa gataatgata
    37921 caattacatt tggaataaaa acttcccttg aaaagaaaaa tcacactgta tgttgttata
    37981 atacgattgc tgaagctaaa aaaaattttg ataaaactat tgatttaatt ctgcttgatt
    38041 taaatctacc tgatggtatt ggatacgagt tttgccaata tgttaaaagt atagaagata
    38101 ctccagtgat atttttgaca gtccgtgatg atgaaaaaga cattatacgt ggattagata
    38161 tgggtgcaga tgactatgtg gttaaaccgt ttttgctctc agtacttcaa tccagaatta
    38221 atgcagttct tagaagaact cattcaaata ctaacaatac tattacatgt gaaaatataa
    38281 gcttgaataa ggttgaagtc aaagcatatt tagataatgt tgaagtacct ttgacagcag
    38341 gagaatataa acttcttcta agtcttatgg aaaataaaaa tagagctatg actcgtacaa
    38401 agttactaga aatgctctgg gatgtagatg gtaatttcgt aaatgataac actcttactg
    38461 ttacaataaa acgtcttaga gaaaaattaa aaaatccacc ttgtataaaa acattaagag
    38521 gcataggata tagaatggag gacaactagt gaaaactcca agaaatatca acagtacagt
    38581 tgtttttata atattctgct taattgtaac ttttttattg agtgtaattc taacaactat
    38641 aacttctttt aatgaataca atgtactgtc taaggctctt ggtgcatcat atgagtacaa
    38701 tcctaagtct acagaaagta tactaaaatc actgaaaaat tctagtgata aggattttaa
    38761 aacaggaaat gaaattttat caaaacatgg atattctaaa agtacatttt ggagtaaaaa
    38821 ctttttttat tttctagtga tatcgtttgg tataatttca acaatggcta cagttgtata
    38881 tataatcaaa catagaacaa ataagcaaaa actgagtaga ataaacaatc ttactcaata
    38941 cttagaagaa gtgaatttag gaaaagagtc tgtactttta cgatgtgaag atgaattttc
    39001 tcaccttgaa gatgagatat ataaaacagt tggggaactt cgttgttcaa aagaatttgc
    39061 tttaaaagaa agacaaactc tttcagataa ccttgcagat attgctcatc aacttaagac
    39121 tccaattacc tctatgtcac ttatggcaca attactttca gaaaattgtc cagatgaaga
    39181 aatagattat attaacagac ttacaaatca aatctcaaga cttgagagac tagtttcatc
    39241 tttacttaca ttatcaaaat tggatgcaag tactttaata tttgaaagca aacttataga
    39301 tgtacattct cttcttactt atgcaattga gcctatagaa ggttctttaa gagaaaaaca
    39361 tcagacattt actatcgagg cttctccttc ggtagaattt gaaatcgata ttaattggac
    39421 tttagaagct cttttaaata ttcttaaaaa ttgtagtgag catatagaag atggtggata
    39481 tatagttgct tattatagtc aaaatcctct atatgttgag attatcatag aagataatgg
    39541 taaggggttt gctcaggaag aacttccata tatttttaat agattttatc gtggtaaaaa
    39601 tgctagtaag gacagtattg gtatagggct tgctctatca aagtctatta tagaacgtca
    39661 aaatggtact ctacatgcag aaaattgcca taatggtggt gcaagattca taattaaatt
    39721 ttacacataa aatgctggat tataggtaaa atacctataa tccagctata tctatattct
    39781 atgttatcta ttgttttagt aatatacttc tatttacatt taaggtttta ttaaacaaac
    39841 aacttaacta tccctatact tgtaagtagt cttaaatcga aacctttaaa taagttcaaa
    39901 tagattttgt ttatattgtt tcatttttta tagattctac tatattttca ttcttcaact
    39961 gcttgtatcc tgtcatatat gatgctatta caataaaaag tatcaatata gtaaaaccta
    40021 ttattgtaga tataggtgca aatggtaaat actctataaa atatatttca tttatacgta
    40081 gaaaagcata cactattcct atttgcacag gaatactaag tagtaatggt gtaattccta
    40141 agaataaacc ttccaaaata agcatctttt ttatgccttc tggagataat ccaacagaac
    40201 gcaacatagc aaactcttgt cgtctacttc taatatttcc tgacactgta gcaagtacat
    40261 ttgataatcc aatcatagcc aataaacctg taataaagcc tactattaaa ttcatggtct
    40321 ttattccact agccttttgt ttttcacttt ctaaaacatc ctcaatacta taatctcctg
    40381 aaccatagtc tttattataa atggactcta atttttctct tactctagga atgtcctcac
    40441 gattatttac tttaaatact cctatcagcc tatttgaacg taacctactt acttcatcat
    40501 aatttttaga tatttcctgc accatagaca ttggaactat ttgcattaat gtatactttg
    40561 aactagtatc tactatttta ggaagtgtgc ttgtaatagc tcccactttc atgttgtaag
    40621 tataatcccc tttatcttcg tcatatactt tttcatttaa tttaatgtta tctcctattg
    40681 aaagatttaa ataatctata tatactttat ttctacgtgt actacgatta atatcttcct
    40741 ccttattata tacaattgag gttggatttt ttgtatcata aaataacttt gggtctacag
    40801 aaatttgcct acaatattct gtaaaactct tatcatcaag cccaattata tttgaaatta
    40861 tacgaaactt gccatcacgt tctataggag agtacttttt agatgaagct atatttttaa
    40921 atcctccatt tttcgcaagt tcttttgaag catctttttc agtcaaccaa gtggaagcag
    40981 acattttttg ataatatagt gaacttttta caccttctgt attatctaat ttttcaatga
    41041 aagcagactc tacaggttca ctattttcca aataaactgc tatatctctt tggtccttat
    41101 aattatcact tccataaaca gcttttgctc cttcttgatt tgcaattata tgcaaaaaac
    41161 atgtaagtaa taaaaaagat aatgttaaag atattgttgc agtacgataa gattttttac
    41221 gagcacgtag tgcgtttgat gcaagttctc cttctattcc aaatatcttt cctaatgaat
    41281 atttatgcga ctttttgatt ttaacactat ctccttgtcg tattgcttct ataggagata
    41341 tctttgatac ttttcgtgct ggtataagtg cagaaatcca gactgttact attgtaagta
    41401 aaactgctgg cagaaaagca ggaataccat aagtaaatac cacttctgga acatcagtat
    41461 gataattaac tgaattaaca taaactataa gcctattaca caataaccat cctaaaaata
    41521 aacctattgg taatggtata attgtcagta aaaagccttc aaacactaca gaccttttaa
    41581 tttgttttgg tgatgcacca acactagata atatccctaa ttgagtaagt ctagcatttg
    41641 cagacagtga aaacgcgttg taaatcacca ttacaaacac ggctactgta aaaattgcta
    41701 ttgtaagata cataatagga gttgaaaatt ttgatatact actcatagat gctttctgtt
    41761 ctggtgaaaa gactaacatc tttaaaagat aattactatt gtatttaaga ttgtattttc
    41821 catattcatt agtcttccat cccaatgatt tagcaagttt tggaagttcc ttatacgtgt
    41881 ctcttatatt tttaaatcgc aagtacacag ttatactatc attaggtttt atacttgttt
    41941 tatcaagata tccaagagct gtatatgcag gtattactga tgaagtagaa acatctacct
    42001 ttcctactat tgtcaatgta gcctctgaaa tttttttaaa actttcccct ttcgattttg
    42061 gggctatggg ttcaagaggc tttccattta ggattctatc tcctattggg agagtaattt
    42121 tatcaccaat ttttacactt ggattattct caaaatattg ttttgataat gcaatttcat
    42181 tagcattatt tggtcgacga ccctctatta tagtatcctt ttctggcata gaattccaat
    42241 actctgatgt agcatttcta taaattatat aatctctttt ctcatcatta attttgccta
    42301 cataccattg tccttttacc attacatcat caactgaaga aaaattttca attaatggta
    42361 agtcacttcc ataagtatag tcaaacaatt caccatgcca gttaccttct ttctcaattg
    42421 aaagttttat aaaatctgtc cacatggtat acaacagtcc acacaaagaa gacatcatgg
    42481 ttgtagtaag taatatagct aacattatag ctatactact acgtttattg cgtcgtacaa
    42541 agtctaaggt gtattcttga agaatattca tttcttcacc accttttcag agacaatcac
    42601 tccatcttcc atagttacaa tacgatttgc ctctagtgct attttctcat catgagtaat
    42661 aagaagtatt gtctgattaa attgtttatt tgataagttt aacaagtcta caatttcttc
    42721 tgaatttttt ctatcaagat taccagttgg ctcatctgct aataaaatag ctggtctata
    42781 gattaaactt ctagctatag ataccctttg ttgttgtcca cctgaaagtt gacttggaag
    42841 atggtttaat ctatcagata atcccaatat agatacaatc tcagagaatc tatcctcatc
    42901 cacctttctt ttatcaagta acatgggtaa taatatattt tttctaacat caagggtagg
    42961 tataagatta taaaattgat aaataagacc tacttttcta cgtctaaaaa ctgcaagagc
    43021 ttcttccttt aaacttgata tttctgtatc ttcaacataa atctttccag atgtaggtct
    43081 atctactccc ccaagcagat gtaacaatgt agatttgcca gaaccagatg ctcctacaat
    43141 ggatacaaaa tcaccttttt gaactgataa atttacatta ttaagggctg tcactctggt
    43201 ttgatttgaa ccatatattt ttgtgagatt ttcacatttt aatatttcca tatacaatca
    43261 tctcctttat ggttaaattt tagcaaccta aaatgacatt atagtgacat gaatacaaat
    43321 ataaattact attaaaaata ttgtttagtt tttgcacatt atttaaaatt ataatataaa
    43381 acaaaaacta tgcaatatat tttatttata cttttaatat attacatagt ctttaaaagg
    43441 tattaacttt aaatctatag gtattcaatt taataatcaa tagcaagtat tttatgtact
    43501 aaaggagttt tgctctatat agactcaatt tagtaaaatt atttaataaa tattacagac
    43561 tataggtaaa taatatttac aaataaaatt aagtttattc ccttacacta taatatttct
    43621 taattatatt aattgcaatt tcctttacct ttggccctgt aatttcttta ttggaatcat
    43681 ctgatttaat agcaaaataa taggtgtcac cttcacgctc tagcatacca acaaaccatg
    43741 catccacacg tttatttttt tcatcaaatc ctgttccagt ttttccatat acatttatgt
    43801 ttttatcatt tacatctatt ttcataatat ctcttaaaat attaatatgc tcttttttaa
    43861 agtttgtatc tccctcaaat atttttgcca ttgtttgcac ttgttctttt ggagatattt
    43921 gtaatgaaga ttctaaccaa aatccattta aatgtccctt tccatttttt aaatctcctt
    43981 cccattcgct aatatcgcaa ttcccatact ttaaatcatc taaaatgttt tggacagatt
    44041 tagcatcaac tttatctatc aattttttgt agtaccaaac acaagactcc ttaaatgcct
    44101 cttctaaact aagattttta ttccaatttt tatttggata ctctgtacca tcatatccca
    44161 taactgattc ttttgagttt attacccctt tttctaaacc aattaaagtt gaaactattt
    44221 taaaagtaga acatggtgac cttcttgttt caattaattc tttgttatat atattatatt
    44281 ctttattttt agtattataa aaaatagctc ctccactaat accttcaaaa caatcactat
    44341 agtcaaccat attaattttt tcttttttgt ttttattatt gttttcaatt ttggatttat
    44401 ttaattcaga cttatttaat tcagatttta tataattctt atcagttttt tgatttatat
    44461 cgttatgttt tttccctaca taatacatta ccataactac accaaccaat aagatagcta
    44521 tccaaataaa attctttttt cttttcataa tttatatcat ctcccatatt taaatttata
    44581 acctactatt aaaatagtag acattatttg taatatactc caatctaggt tctacttata
    44641 agaaacaaga ctaaatgaat agctgtatct cttatatttt cttcacctag tacaattatg
    44701 ttgattaaac ctattgcgaa gataattaag taactattaa taacatcctg tcctcctttt
    44761 aatttgtgat ataataattg attccacatt taaaacttac tattgtaata tttaaatatt
    44821 acaatagtaa gttttaaatg tcaagttagt ttgggaaagt tattttaatt gtataattgt
    44881 tattacattt ataaaatatg gcatgtttaa aattattttg ctattgggag gattaagata
    44941 agcagtatta taaaagctat aaattataaa atttaatata taatttatag cttttacttt
    45001 tacaaatatt gtttttattg atttattaat gaattttatt gacaggttat atttatataa
    45061 gtaaacactt acataataag tatataatct acatatctat aagttgagtc aattcaccag
    45121 tatatgtcaa cttaagttta tgcatagctc gtgtacaagc aatatataac aaactgcggt
    45181 cataatcact ataatatgtt ttattattta ctgaaggtac aataacttca tcaaactcta
    45241 aaccttttga cattttaata gaagttatgg atactccttt tgtaaagcta gaactttcag
    45301 aagatattaa gtgaacacta tatttttctc ttaacgcatc atatacagct ttagcgtcat
    45361 tatctgtctt taatataata ccaagagtcg cattatcact ctttttaaat tcttcaattt
    45421 ctatttttat cttatttatt tcatcttgct cgttattaca ttttaataaa gctggttctt
    45481 caccatgtcg ttcaataggc tctaatgaag atatgtcttg aatctttttg gcgaaattaa
    45541 taatctcaaa agtagaacgg taactcttat tcaacataac tagttcccca tcattatata
    45601 gctgtttcat atcatctagt gtatgagtgt gattaggatt aaccaattgt ccaaaatctc
    45661 caagaatagt ctttttacac ttaaaaagta agtttattac agcatattga ataggtgtgt
    45721 aatcctgcat ttcatcaata acaacatgtc ttataatctt atcttcttgt ataccttcat
    45781 atgcagcatg aatatatata aatgggtata catctgacca ttcaagagtt ttttttgttg
    45841 ccatcacaaa catgtttgat atattcattt gtttaaagaa atccttatat agtgtaagag
    45901 tattttttat tgtcaacatt ccattcaaac ttttaagtat actttttacc tttggtaaat
    45961 cttcttccat aatattatct gattcaaatt tataatgaat gtcttcagct accttctcta
    46021 atctcttctt aactggatat ctgttatatg cctcaaatct actctgtatc cagtcacttt
    46081 tagctgtaaa acttccaaaa gtgtagtctt ttggaataaa aatcttattt ggcatttgtt
    46141 ttatataatc atcaataagt tttacaaaat caagtgtaga tttaaaacgc actctttcag
    46201 accatttagc atcatttatt tctaatgggt ctttctcact ttcaaaatta ataactctat
    46261 ctaattgtac ctctgctata ttttcaaaac ttaattcaca taatggctct tctccaagct
    46321 caggaaggac attggaaata tagtctccaa agactttatt aggtgatagg ataattacat
    46381 tatttgctga tattttatct ttaaatcgat aaagaagaaa agcaattctg tgtaatgcta
    46441 tagatgtttt cccagaacca gctacccctt gaataatcag tgtatcagct ttatcatttc
    46501 taataatttg attttgttcc ttttgtattg ttgaaatgat tgacttcatt ttttcatctg
    46561 aagtgtgact aagttctttt tgaagaatat catcttgtat attaatggaa ctttctagtg
    46621 catattctaa ttttccattt ttaattttaa attgtcgttt tcttgttatt tctccatcca
    46681 cccatcctat tggagcatca tatccagctt ttccgatttc ataatcataa aacatactgg
    46741 caattggaga acgccagtca agtattataa gctcatcttc ataatcaaat gcaaatctac
    46801 caatataata cttagattca tcatccatat ctttcagcct aaaatctatt ctagcaaagt
    46861 atggagaatc tttgatttta ttaatcttat ctcgaacttt taccataaaa gccccatagt
    46921 tatctatttg ttttagtcct tgttcatttt gaaacatttc atgtgggtct atttcaccac
    46981 gattttttac catatacatt ttagcgtcca tataatcctt atcaagcttg tcaacaagat
    47041 tttcagcttt cttaaaagca ttgtctagct tgttatttat ctctattaga tgtgcaatct
    47101 catctggaaa aaaagttaat aactctgcat catattcaca catattatgt ttagaattag
    47161 atgcaataat atcgcaattt actacttgtt tattttcaga catttaaatc ctcctttgtt
    47221 aattaagtac ttacactgaa tcattatact taattgtgtt ttggagtttt taatcattct
    47281 tgctatttaa cttaaatgtt agctttttag ctttaaagtt ccttttttaa aaaactaaat
    47341 ctttctatat ttattaccat aagtacactt acaagcaaaa tacattaaaa gcagaaatgc
    47401 tcttatatat aaaataattc aaacaaaaaa tatgtggtaa acttttcatt taatctacaa
    47461 ttaattttgt ctattatctc tttcttctac acaaggaaga ataaattttt gagtaggata
    47521 tccaaattcc acaagcaatt ctgcttctgc aaagcccaac ttctttatca tatctctatg
    47581 tcctgtatca gctttgtcac cctctcgaaa ggtagtaatt gaaatatctg tatctatcaa
    47641 gaaatcttca ataactttct tcaaaaacac ttgtgcaatg tctgaattac gatactgtgg
    47701 atgtattcca aaaaaatcaa tacttctagt ttctctatta aacaccatat ttgcaatagc
    47761 gacattatta agttttaata ttaaagctct ttcttctaaa atatactgtt ctaattgata
    47821 tatatattct tcctcttgca aatttggaaa tccatctatg actaatctca ctaaattcat
    47881 ccataatggt atgtcagaca tacttgcaag tttaatttct ttttccaact ctagtacatt
    47941 ctttgaaaat aggttatctt ttttcaaaac aaatcttagc tgcaaaggat aaaattcttg
    48001 ttctttccta tatttatttg gagatttttt atacatagct ttaaatatag aagtgaatgc
    48061 ctgttgactt tcatatccag ctatcaatgc aatttcaata attggtttct ttgaaaatac
    48121 caataatttt gctgcttctg tcaactttct ccgctttatg taatcatgca ttgttagacc
    48181 aacagaagtt gtgaaagttc tatgcaggtg atattttgag taatgaacag cattagcaac
    48241 tatatctaaa tccagctttt ctgataaatg ctcctctata tagtcaatag cagttatgac
    48301 attaattact ttgtaagaca ttgcagcttc cctcctttta tccatgcaac attatatcaa
    48361 ttattactta gttatattta atgaatcttg ctattttata aacaaatttg ttgtttaagt
    48421 tttcaattca taaatttaat atattacttt ttactttctg attaaagact ctaatccttt
    48481 aattttcaat aacttttcat ttagtaaatc taaaaagtta tttattattt tcttcttatt
    48541 agattccttt tatattcctt aattaaatga taaatattta tattatacga ctaaaaacag
    48601 ctttttacaa ttatttaata tgattacaaa cttaccctat cttaaagttt aatggggtcc
    48661 tgttatgaat ctttttattt taatttaagc tcttcatcag tttattttat atattgatgt
    48721 atttgatttc atacaaaaaa gagtgcttca tgaactaaaa agttcatttt taaacactct
    48781 cttttatgta aataaatttc tattctattt tgaaatatta taatttgact tataatctgt
    48841 taataccaaa aataataaat tgtacgtcta agaatagatt ctaattagtt gctcagtagt
    48901 aaaatctgtt tttaactaat cctgctttgt atgttgaaca tattctataa ttgtaccatc
    48961 tggatgtctc aatgtcatat tatatcctgt aggaactttt ttcttatctc ttactacaac
    49021 tgctccatta tccaatagat aacttctcca ttcatcaaca gaatcaacca taaaagtaga
    49081 ttttgtttct ataaatggtt taagagcatc atcagaacca gataatagta aaacatttcc
    49141 tatttgcgct aattccaacc caacttcttt ataggaaaaa cgcaaagaac atttttcttt
    49201 taaaagattt tcataaaaag gtatggcttt ttctatatct tgaatataaa aacgtgttaa
    49261 tatatcatat attttcatat tttcccccta tatatctata taatattacc tctaaattat
    49321 accactctac aaattatata acaataaatt aagcatagcc ttttgagcat cttaagtaga
    49381 ccttaacaat atattggggt tacattagaa tacataaatt aaatcacctt gatattattt
    49441 aggataaaat ttatgtagta gcagtaaatg ttcttctaat tatcaactaa caaacgataa
    49501 tctttaactt tctatataat gggtaacatc attttcgtaa gatattcact agctggacga
    49561 ttgatatcat ttaaatactg gtaatatata tcgccatgaa gtttatatcc attgctattt
    49621 gcccatgaaa ataagtcttc taaagtaggg tcttgtaatt cataaggtcc taaatcaatt
    49681 gcagttatta ttttctgtgc aggaacaatc ctttgtagaa tctcattttt cccatctata
    49741 taagtggcta caggaaaccc tacttcaaca tccaattttg ctaaatccat gttatgaaaa
    49801 catacaatcg gtgctcctga agataaaatt cctctctcct ccagatattt agaaattttt
    49861 tcaaaacttt gttttgaaaa ctctgaaaac tctaccataa agtcaattgt ttttcgtatt
    49921 gccaaaaaac agtactcaga ttgttcagct attgttatat tggatattct agtcatttta
    49981 ttcctccatt actttatttt catttctaat ctttttatac caaattatac gaaaatttac
    50041 tgtgtaacta attatttcat atgaatataa aacataacct ccttccattt cttatatcga
    50101 aagtatagca aaaataatct catcattctt gtcacacagt gctcttataa tcagaacata
    50161 cttaaaagac ttgcctaatt tttaggcaag tctaaaagaa atctttttct ataaaaaatt
    50221 tatacaaaca attaaaagat caaaatatag actaatataa aactataaat ttactaatct
    50281 gaacctccca tggctaaagt cacaagatta ctgatttata gaatttcgca cactaaaata
    50341 tgtcttacta attccccaca ggctaccccc ctagttccta cgttcttaca taagttatct
    50401 attatcaaac atcaaaattt aaacaagttt caggttcatc ttctattctt gctattttaa
    50461 acttacatgc aattaatact aaagatacta ttggatttat aatatttaat aaagcgtatg
    50521 gaccatatgt tagtgcagat acacctaatg ttgctgttat atacgccccg catgtattcc
    50581 atggtactaa tggagaggtt aaagttccac tatcttctaa agctctcgac aacatcttag
    50641 gatgtatacc tctcttttta tattccttat tatacattct tcctggtata actatagata
    50701 gatattgttc acctgctatt atattggtaa ttgtacaagt taccatagta cataatactg
    50761 ttccaaatac accctttgct aatcttagta aagaagatgc tactacttca agcatacctg
    50821 ttttttctaa aatacctcca agagataaag cgcatattgt taaggataca gtggacatca
    50881 tattcataat cccaccttta gataataaag catctacctc ctgtatttgt gttgacgaaa
    50941 catatccatt ttgtgctgca tctaatatcg tattcataga ttctccttga aaaactactg
    51001 caaacaatac tcccaataca gcacctacta taagccctgg tatagcagga actttaaata
    51061 caaccaatcc aattactatt gctggagcta ataataatac tggtgataaa gtattaaatg
    51121 tagaatctaa tgtagaccta attaattcta tttgttttat atctagtgct tgacctgaat
    51181 acttcattcc aattacacca taaattacta aacaaattaa taatgatggt atagtcgaat
    51241 atagcatata ttttatatgt gtaaacaaat ctgttcctgc cattgctgga gctaagttag
    51301 tcgtttcaga taaaggtgat agtttatctc caaagtaagc tccagatatt atagaaccta
    51361 cgattaatcc aattggcata cctaaacttt gaccaatgcc taaaagagct actcctactg
    51421 tacccattgt gctccaagat gaacctgtcg caagagatac tattgcacag actaatgttg
    51481 atgctactaa aaaaatattt ggtgataaaa tttttagtcc ccagtaaatc atacatggaa
    51541 ctactccact tactatccaa gttcctataa gtacgcctat tataattatg attaagattg
    51601 cttgcattgc catctttata ctattaaaca tacttaattc taactctttc catttaaatc
    51661 caagtctata tacagccaca agtcctgcta ctgctgctgc tcctattagt ggtacatgag
    51721 gtgatgaacc atacactaat actcctagac ttaaaaataa tatcaaacaa gtaattggta
    51781 tcattgcatc aaacagactt gcttttctac attctcgctc tttcataaaa tagtttcctc
    51841 ctaattattt aaacactaca ctataatttt ttttgaaaca tatttgctcg tactagatga
    51901 catgataccc ccataagtta ataaaaattc taaattgtca cctaatttat aatcatattt
    51961 tgtgttactt acatctagta tcatgtggtc tgaacttgcc cctaatattt ttatatcagt
    52021 gtctattgga attaaagagt caatatttat atcttgttta cctatagcta tgattgccct
    52081 ttttaagatt cccttatctt cataaacagg tttatttcta aaggcatcaa ctcctatttc
    52141 tccaatagga actgatggtt tttctttaca ttcaactact tggcatatta atttaaatgc
    52201 atcttgatat gttccattta tattttcacc gtatgccgtt tctctaccaa gtagaatgga
    52261 ctcgcctatt ctcaaattag taataccttc tggcatatta ttatttatca acagatgaat
    52321 agaacttgaa ttacctccag atactatttc tagatttatt ccaaattttt cttccattct
    52381 ttttgctata cttaccagtc tgcctatatt ttccctagat ggtataatag ctccataaca
    52441 ggttaagttt gtagctatac caattatttc aatatttttt aatcttacta tctctcttac
    52501 attactaaaa aagtcttctt cataaaagta tccttctcgt aaatcgccta agtcaaacat
    52561 aagaactatc ttatgaataa tatttttact ttcacataat tcatttaatt tctttattgt
    52621 tcctaattct gagttaaaac taatatcgca ataattgata acttcttcta attcacttaa
    52681 cattgggatt ctaatcaata tcttaggtag atttatatct tgtaaatttt ttaagttttg
    52741 tattcttgaa tctgctatat ggtctattcc ttcactacat atttcttcta ctatttcttt
    52801 ttgtgcacaa aatgatttag taacaaaaga tatcttaata tttctttcat gacacatctg
    52861 cgaaattaat tttgcattat gctttaactt ttctatatct atttctaacc taggatacat
    52921 aatctttcct cctcaaaatt caaacttttt aacaggagct taagagatgc ttcttcatat
    52981 tttttagata aaacacccat agatgccata atatagtcat tatctattaa tatctttgtt
    53041 ttttcctttg gaaatagtaa ttcattattt ttattgtatt tgagcatatt atctaatatt
    53101 tcaattctac tagggagcct agtaagtgct ccccctgtac caactatata tcttacttct
    53161 gttaaatctt tcccttctgc aattttgact tttccagttg ttccatagat atttcttatt
    53221 tttcctgaat gtcttagcat agctttaaca acagcttctt ttgtcaacct ctcaacaaat
    53281 aatatttctt cttttgattt tggtattgga ggataattct ctattactgc atcaatatct
    53341 atagatagtt cactttgtaa gttttcttta cctataactt ctactatatt cttcatattt
    53401 acatatacac ctaaatcccc ctcaacactt ctctttgcag taggttcagg attaaccaaa
    53461 attttattaa tatagtcact tccatctgta acagaatgta catcagtagt tgctccacct
    53521 acatccagag ttaataaatc tccaatattt ttatataaaa gtttagaagc ttccattaca
    53581 gctcctgggg ttggagtaat attttcatta accatttctt taatgtattt cattcctggt
    53641 gctgtagtta tgtgttcttc aaatacactt tgaatgattc ttcttgtagg ttctatattc
    53701 aataaatcta ttttagggta tacattttca gttatataaa gcttataatt agtatcttca
    53761 aatattaacc ttatttcctc ttgattttca acattaccag catatataac tggtatgcct
    53821 agattcatag aagctatcat ttctgcatta taaatagctg tatctctttc tccataatcg
    53881 actccaccag ctattaaaat tatgtttggg tttatttctt ttattttatt taaatcagtt
    53941 cttttaattc tacctgatgt tatttgacga ataacagctc cagcccctaa agctgcttct
    54001 ttagctgctt ttactgtcat atcatagact aatccatgaa cagtcatttt taatccacca
    54061 gctgcactag aagttgcaaa catatcatta tactctatat catctacaga taatttatta
    54121 gctaaatctt taatagcacc tgataagcca tttcttacat cgccaccttc aaacactgtt
    54181 gttggagctt gaccttgacc caaaaatata ggattgttag tattaatatc gtggaaagca
    54241 tttaccactg tagtagtact tccaatttca gctaccaaca catctatttt taaagaaacc
    54301 ttgctatttt ccattattta ttactcattt ctcttctttt ttcaactaag aaagtggcta
    54361 catgtatgcc tttactgttt cttccaaatc cagcatctat gccttgttca acagctattt
    54421 caggtgttac ttgtgttcct ccacacgcaa tcattacttt atctcttata cctttttcta
    54481 cacaataatc gtgtaatttt ttcatgtttt tatagtgaat atcatcatga cttattattg
    54541 tagatgcaag tattgcatct gcattcagtt caatcgctgc atctaccaat ttttctacag
    54601 gtacagaagt ccctagatag tggcattcta tgccatattt ttcaatacct ccatgtttta
    54661 tatctattat ttctcttaaa ccaactgaat gttcatcttc tccaaccgta gctgaaacta
    54721 ttttcatagg tttttcttct atatctgctc ttatttcttc atcagttagt accttaggtt
    54781 cttctggtat tactaaattg tttaaatcta tatcaaacgg aactcttcct ttcacttcta
    54841 ttctagtccc ttcagattca tgcataactt ctctacttat gacctcaatt tcttgtaagt
    54901 tcattttttt gacaaattcc aaagctgcaa actctgctgt tcttttatca gtaggaagca
    54961 tcattgttat cattacaatt ccatctgcac accattccat ttcaggctta attttagttc
    55021 catttctgta ctcatatgat tcttttagtc tattttctac attatcaaaa tcgtcaagct
    55081 catcaatata tattattttg tctggatttt caaatgtaca tccatctatt aacattgatg
    55141 gattatctat agcattttca tcatattgag ctacattatt gtatccaaag tgagcagtta
    55201 caggtgctaa ataatcttct tctctttcat aaacagtacc ttcaccaact ccacctttta
    55261 tttttctaga tattccatca ccatttcttt ctggataatt tccagaatca acaaaaaatc
    55321 cttgttccac agattcaaaa tatccaccaa cttcagatat ttcttccata tataatacag
    55381 ctctttcttt aagttctctt gctttgtctc ttaattcacc cacatcttta agttctatca
    55441 tatccataag cccatccata ccaactaaag cttgctttgc tgtatcacat gcttctatat
    55501 tgtatatatg ccaaggtaca tttctacctt catcaggtgt tatagttgat tgtatgtcag
    55561 ctctagttaa tactgatgtt aataagttta atacatgagt aactgttgct tctctagttg
    55621 atgattccat atatttagta ttcatttgag ctctcatctt ataatcacta aataactctc
    55681 taagtgcaac agcgtaaggt aagtctattt ttaaacatgg tgctggaggt gctgttggtg
    55741 gaactgttga taagcatata ttacttttat ctatacctat tttttctgaa aatatagagt
    55801 ttaaagcgtg ttgaaccata agttcaggca ttaccttcca tgcttctcta gcagtagcat
    55861 tagcattatg tgctccatca atttgagcta tattggcaaa agccattatt ttctttgcct
    55921 cacaagcatc tacaaaagac cttaccatgt ttatattcct atacagaaca ttatattgtg
    55981 ggtcttgatg tgctccattg actccttcct cagcaaacat tactgctact tcaggaccag
    56041 caacaccact tacatatgaa tggtaattaa taggtctacc aacttcttct tctataaaat
    56101 caagagcctt cctttgagct cttacttgtt ttcttgttat tggaactcca cctatacctt
    56161 gtggagttcc ttctataagc ccatcaaaat gtgattgtcc agcagttctg ataaccatta
    56221 gatggtcagc tccatgatga gctgccattc tcattcttct tatatcatcc tcaaatctac
    56281 cagaagctat ttcagtagta ataactggac ttggttgagg gtctatatta ttgaaatact
    56341 tagatgatgg tagccctaca ctcttcttta aaggttttgt acagtcttta tatttaaaag
    56401 gtcccatttc aagattttcc aagtgttctc tccaaaccca acctcttcgt tttggtttat
    56461 atttatccaa atcttttaat atatagtcta tatccaattt tttattttcc tttaacatga
    56521 ttctacccct tctctaaata aacatgtaac ttcatcccaa tattcaccct taactaataa
    56581 caaacctgct tctctaaccg ttatattttt agatttagcc aatttataaa ctacatgccc
    56641 tgctccttta cctataagac ctctttccat aaccccttct aaaataggtt ttacttcaag
    56701 agaagaaaat cccattctca acaagacaga cctttctatt gatggtgttg tattcttttt
    56761 accaagttct atcattggtt ctactatctg ggtagctaaa ctccaaaacc tttcttttaa
    56821 ctcatcatca ctcagttctt gaagatgttt tcttctaact tcaaaatcat cctctctttt
    56881 tttcatgaac attcctccat tcgtattgat ttaatcgaat tttctgaatt tttattttat
    56941 attaaattaa aaaacaataa ttactataaa ttatttaata catcaacaac aaaatctctt
    57001 gaacttttta cttcttccat taaaaattct atatctcgat tacttagctt atcaatatta
    57061 tcaatgtgat tattagatat acaatttttt ataaatgact ttcttatttt attcatatca
    57121 atatcaacac atttcaataa ttctggtctt tctggtaata ttaagtttac tcctgcaatt
    57181 tcttctcttg gatttccaaa ttttatatct attccatttt ctcttgcaaa agtaagctgt
    57241 ggacatatat gtttacctgc gcctgtatat tctgtttctt gtaccactat aactttatcc
    57301 tcatctaact cttgagctaa agagaatgct gctgctaaag atgtatttcc tgctggacct
    57361 ctttctatac cttctagctg tgccaataat tcagttgtat aaaaaacttc tccttgtttt
    57421 actaatacat atctatccat atatctaagt ggtctagctg cagacctagg tacatctgac
    57481 ctatcaggcc atgtacagta tggtatccca aaacctgtat gtcctgttgt aaatgatttt
    57541 ttattaaatt gattatcact agccatgtgt aatcctttta aatctacact tgctcctact
    57601 actttagtat taatagaacc agcttttatc aatcctcttg cagttccagt aagattacca
    57661 ccacctgcat ttgtacaaac aactatatca gggtcttttt tatacttttc tctaaattgg
    57721 atagctaact cataacctaa agtttctaca cctgcaattc caaatggtga atataatgat
    57781 gcgttaaaat agcctgtttc ttctaataaa actaagaacg tataaaataa ctctggtcca
    57841 acagttaact gaacaacttc tgctccatat gcctcacatt ttcgtgcttt ttctataatt
    57901 tcaggttgac ctacaccatt agaatcataa cattcttgaa ctattataca ttttaatccc
    57961 tgcattgccg cttgtgatgc tacagctgca ccatagttac cactagtagc tgctattaca
    58021 cctttatatc ccatttgttt ggcatgatat actgcagtag ctgctcttct tgctttaaaa
    58081 ctaccagatg cattcattgc ttcatctttt acaaatattc tagctccttt accttcttta
    58141 gcacattttc tagctaattt agtcaaattt ttaagctcta ttaaaggagt atttccaaca
    58201 gcatactgtg attgaattgc ttcaatatct tgtaatgtat atcctgtttc actcatcatt
    58261 ttctcataat caaaccctat tccctcttgt tcaaaataag aataatccaa tccgattgca
    58321 tttttcatta tttcgttatt tcttcccata acagcttgat aactcatatc tttcattgat
    58381 gttgaattat tcattatata cacctccaaa taatatttct ttagcttgga ttcctatttg
    58441 gagtaactct ggtatacatt taccataatc atgagtataa tatggattta ttttaagtaa
    58501 attacctttt acaagtctgc ctgtaattgt tttaacttct actaagtcgc ctatagaagc
    58561 atcactttgt ataaaacctt taacccacat ttctaaggat actttcttag tatcctctgg
    58621 aacttgtgga gctctttctt ctggagtcaa tactatattg tgtataataa cccaatcatt
    58681 aattttagca tccatttttt catcccctta ttaattgact attgccttac taattaattt
    58741 actgttattt taaattaaac attattttac caattagcta actgttatct tactaattag
    58801 ctagttgcta tcttactaat tagttagctg ttatcttact aattagcctt tgattcttct
    58861 tccaattcaa cttctatctg atttcttata tctcccatta ttgctctagg tactggtata
    58921 tccaacatag ttttaagacc tggtctagca tttattatta atggaataga gtttactatc
    58981 attgcataag tacctactcc tccaggtatt tcaggattta tttgtaaatc aatgtttggt
    59041 atacctttta ttgatacata gtctcctgtt ttaatacctt ctgcttctgg tattatctgt
    59101 tgtggatgct ccatttcaat taaaacttct ccatttacat atccatatcc acattgtcta
    59161 caaccagcaa catttccagc caatgcctct ccgtacttag attttctatc tactgtagtc
    59221 attattggct cttttgtttg ttctatctta tctaatttcc aacctaatcc atcagctatc
    59281 atatttattg attctacaaa acctacatga cctgctatag tcttatcttc tacacctttt
    59341 ataaattctt cccttgttac tccaacacct tgttcctcca taacagactt tccaaatgga
    59401 gataaatcat ttactctctt agcttttata ctagtaactt cttcacaagt gcctgaaagc
    59461 gccaatacta gtaaatctaa tacaaatcct ggatttattc ctgttccaag tatacttact
    59521 ccattttcct ttgcaacttc atccattttt ttagctaaat ctgcatcatc agcttgtgga
    59581 tatgccattt gttctgctgt tgatataaca tttatttttc tatttaataa gaaaattatt
    59641 ttatcaaaag cctttttagt aaatgaatca gttgctaaca aaacaacatc tacacttttt
    59701 tctctaaaaa cttcttcata atttttattg ataataactt ctggtctttc tcctctttca
    59761 attcctaaaa cattatacat actttttcct gaagtacttc tactacaaac agatactatt
    59821 tctatacctt ctttctttag aatcatatta gccataccta ttcccatagc tccaaatccc
    59881 catattccta ctcttacttt tctcatatat acaccctcct aaaaatttat atattctcaa
    59941 taattagtta aagcataaat cgtgccaact ttaaaattaa agtaaatatt tattgaaacg
    60001 ttgaaactat aattatttta ttatgtattt tcataaataa aaaataatat ttcttatgag
    60061 aaataaaaaa aagagcaaaa tattttgctc ttttataata attttgctcc tctattttgc
    60121 ttttttattt tactttgatt ttgttttttt atcttgctta tttataatat tttgatatta
    60181 tattttttta ttttatactg taaattttgc ctattcatac ctaaaattga tgcagcttta
    60241 gttatattgt aagatgcctt ttctaatgat tcatatatat acttttcttc tatctcactg
    60301 ataatcttac taagtgtttt gtcctccaaa tcgtttaaag aataattgtt actctcttta
    60361 ttctctttaa gattgtaata gtcgtttaga ttaatcatac ttgtttctat ttgtacctca
    60421 tcttccatca tactcatagt acaataaatt atgttttcta gctctcttat gttaccttgc
    60481 caatcgtaat tttttaaaat tttaatagct tcatctgaaa ttcctactac ttttttattt
    60541 aactttttat tatactttga aataaatttt ttgcacaata gaggtatgtc ctcttttcta
    60601 tctctaagag gaggaatttt tatatgaatt atgttaagcc tataatataa atcttttcgc
    60661 attttatgct cgtttaaaat tacctttgga ctttcatttg tcgttgcaat aattcttaca
    60721 tctataggta tatccttagt tcctccaacc cttcttacat aaccttcttg taaaaccctt
    60781 aatagtttag cctgtaacat aataggcatg gaatttatct catccaataa caatgtccct
    60841 ttgttagctt gttcaaataa gcctggccta tctattgctc ctgtaaatcc tcccttgcta
    60901 gttccaaaaa gaataccttc gaatagtgat tccggcaaag ctgcacaatt ttgtgctata
    60961 aatggatagt ttttcctatt acttccatag tgaatggact ggctaaataa ctctttaccc
    61021 gttccagttt caccgtatat aaatactgaa gcatcagact tgcaagcttt cttagattta
    61081 gctattgctt ctttaatcaa attactttcc cctaaaatat catcaaattc ataacccttt
    61141 ttttgtctaa tactaacttt attgactaaa ttttttttat aatttctgtt tagtaaattt
    61201 tctatcgttg tcatattctt tgatatctca agtgccccta caaactcgcc tttaatatca
    61261 attggtattg tagtattaat tgctgttatc tctcttccat ttttatccag atatttttga
    61321 atattgtctt tgataacttc ccttttttcc aaaacttcta atagtgtact cctgtttatt
    61381 ttcattttgt tgactatatc aaaaaatgaa ttggttaaaa tatcgtgtct gttcattttt
    61441 tccatttttt gtacagaatt attgtagatt atagttttcc cgtctttatt aacaaaatgt
    61501 accccttcat caatattttc caatatttca ttcattattt taaaaaatat ctcttggttc
    61561 aactatatca ccccagtacc taaatatata aaaacccaaa aaattaataa aatgttgcta
    61621 ttgtatttat cttatcatat atttatgata ttttttatgt acattatatt aatatatttt
    61681 taagtatatt taaaatttta tttatatatc tttcattatg gttatataca atatttgaat
    61741 tgtcattaaa tatgccaata gttttatata ttattgattt tattaaaaaa agagatatac
    61801 aaactaataa gttgtaatct ctcaaatata aaaaaacaat aaattagctc attggatttt
    61861 ttagtccata atataattat agattattca ccaaacaatc tatagaaatt gtggtattaa
    61921 tgtttaaata accaactttt tctaaaataa cctttatagg aatatatgag ttcataagta
    61981 aagatagcga aataagaaac cagtttggta tgtaaaatct agatttttaa ttaaat
//
LOCUS       DAMJWC010000016        59229 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMJWC010000016 DAMJWC010000000
VERSION     DAMJWC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.016"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            378..1211
                     /locus_tag="PC503_001197"
     CDS             378..1211
                     /locus_tag="PC503_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2527206.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1304..2236
                     /locus_tag="PC503_001198"
     CDS             1304..2236
                     /locus_tag="PC503_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2527207.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2288..2770
                     /locus_tag="PC503_001199"
     CDS             2288..2770
                     /locus_tag="PC503_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2527208.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2782..3651
                     /locus_tag="PC503_001200"
     CDS             2782..3651
                     /locus_tag="PC503_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2527209.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            3694..4449
                     /locus_tag="PC503_001201"
     CDS             3694..4449
                     /locus_tag="PC503_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2527210.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLASLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            4491..5312
                     /locus_tag="PC503_001202"
     CDS             4491..5312
                     /locus_tag="PC503_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HDF2527211.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            5317..6078
                     /locus_tag="PC503_001203"
     CDS             5317..6078
                     /locus_tag="PC503_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF2527212.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    6239..6496
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6609..6848
                     /locus_tag="PC503_001204"
     CDS             6609..6848
                     /locus_tag="PC503_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2527213.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            7152..8147
                     /gene="ilvC"
                     /locus_tag="PC503_001205"
     CDS             7152..8147
                     /gene="ilvC"
                     /locus_tag="PC503_001205"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF2527214.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDVAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            8200..9888
                     /gene="ilvB"
                     /locus_tag="PC503_001206"
     CDS             8200..9888
                     /gene="ilvB"
                     /locus_tag="PC503_001206"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF2527215.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            10099..10776
                     /locus_tag="PC503_001207"
     CDS             10099..10776
                     /locus_tag="PC503_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2527216.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            10945..12981
                     /locus_tag="PC503_001208"
     CDS             10945..12981
                     /locus_tag="PC503_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF2527217.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPAGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(13172..13738)
                     /locus_tag="PC503_001209"
     CDS             complement(13172..13738)
                     /locus_tag="PC503_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2527218.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            14026..14961
                     /locus_tag="PC503_001210"
     CDS             14026..14961
                     /locus_tag="PC503_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2527219.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15426..16640
                     /locus_tag="PC503_001211"
     CDS             15426..16640
                     /locus_tag="PC503_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527220.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(17060..17581)
                     /locus_tag="PC503_001212"
     CDS             complement(17060..17581)
                     /locus_tag="PC503_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527221.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHKQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEIRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHKKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            17937..18734
                     /locus_tag="PC503_001213"
     CDS             17937..18734
                     /locus_tag="PC503_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2527222.1"
                     /translation="MEKREKRIIISSLLSVSILMGLASIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            18844..19434
                     /locus_tag="PC503_001214"
     CDS             18844..19434
                     /locus_tag="PC503_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF2527223.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            19500..21197
                     /locus_tag="PC503_001215"
     CDS             19500..21197
                     /locus_tag="PC503_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2527224.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            21411..22250
                     /locus_tag="PC503_001216"
     CDS             21411..22250
                     /locus_tag="PC503_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF2527225.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            22767..24623
                     /locus_tag="PC503_001217"
     CDS             22767..24623
                     /locus_tag="PC503_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2527226.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGTYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    24706..24946
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    25012..25247
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25332..26549
                     /locus_tag="PC503_001218"
     CDS             25332..26549
                     /locus_tag="PC503_001218"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2527227.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            26666..27148
                     /gene="cdeM"
                     /locus_tag="PC503_001219"
     CDS             26666..27148
                     /gene="cdeM"
                     /locus_tag="PC503_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF2527228.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            27412..28677
                     /gene="hisD"
                     /locus_tag="PC503_001220"
     CDS             27412..28677
                     /gene="hisD"
                     /locus_tag="PC503_001220"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF2527229.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(28880..29632)
                     /locus_tag="PC503_001221"
     CDS             complement(28880..29632)
                     /locus_tag="PC503_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2527230.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(29750..30019)
                     /locus_tag="PC503_001222"
     CDS             complement(29750..30019)
                     /locus_tag="PC503_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527231.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            30494..31588
                     /locus_tag="PC503_001223"
     CDS             30494..31588
                     /locus_tag="PC503_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2527232.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            31590..32540
                     /locus_tag="PC503_001224"
     CDS             31590..32540
                     /locus_tag="PC503_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF2527233.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            32533..33717
                     /locus_tag="PC503_001225"
     CDS             32533..33717
                     /locus_tag="PC503_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527234.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYKKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDAFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            33730..35226
                     /locus_tag="PC503_001226"
     CDS             33730..35226
                     /locus_tag="PC503_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2527235.1"
                     /translation="MSKILEIQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            35249..36199
                     /locus_tag="PC503_001227"
     CDS             35249..36199
                     /locus_tag="PC503_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527236.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            36220..37182
                     /locus_tag="PC503_001228"
     CDS             36220..37182
                     /locus_tag="PC503_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2527237.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            37554..38186
                     /locus_tag="PC503_001229"
     CDS             37554..38186
                     /locus_tag="PC503_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2527238.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            38597..38689
                     /gene="kdpF"
                     /locus_tag="PC503_001230"
     CDS             38597..38689
                     /gene="kdpF"
                     /locus_tag="PC503_001230"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF2527239.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            38730..40412
                     /gene="kdpA"
                     /locus_tag="PC503_001231"
     CDS             38730..40412
                     /gene="kdpA"
                     /locus_tag="PC503_001231"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF2527240.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGVVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            40437..42494
                     /gene="kdpB"
                     /locus_tag="PC503_001232"
     CDS             40437..42494
                     /gene="kdpB"
                     /locus_tag="PC503_001232"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF2527241.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            42513..43139
                     /locus_tag="PC503_001233"
     CDS             42513..43139
                     /locus_tag="PC503_001233"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF2527242.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            43376..44284
                     /gene="cysK"
                     /locus_tag="PC503_001234"
     CDS             43376..44284
                     /gene="cysK"
                     /locus_tag="PC503_001234"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF2527243.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            44311..44901
                     /gene="cysE"
                     /locus_tag="PC503_001235"
     CDS             44311..44901
                     /gene="cysE"
                     /locus_tag="PC503_001235"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF2527244.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            45061..45249
                     /locus_tag="PC503_001236"
     CDS             45061..45249
                     /locus_tag="PC503_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2527245.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(45303..46172)
                     /locus_tag="PC503_001237"
     CDS             complement(45303..46172)
                     /locus_tag="PC503_001237"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF2527246.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECI
                     VLVTETGVEILTE"
     gene            complement(46369..47613)
                     /locus_tag="PC503_001238"
     CDS             complement(46369..47613)
                     /locus_tag="PC503_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527247.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDGLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            47904..48215
                     /locus_tag="PC503_001239"
     CDS             47904..48215
                     /locus_tag="PC503_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2527248.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      48308..48400
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            48500..49294
                     /gene="thiD"
                     /locus_tag="PC503_001240"
     CDS             48500..49294
                     /gene="thiD"
                     /locus_tag="PC503_001240"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF2527249.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            49318..50106
                     /gene="thiM"
                     /locus_tag="PC503_001241"
     CDS             49318..50106
                     /gene="thiM"
                     /locus_tag="PC503_001241"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF2527250.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDALSKNSNIEFLN"
     gene            50129..50761
                     /gene="thiE"
                     /locus_tag="PC503_001242"
     CDS             50129..50761
                     /gene="thiE"
                     /locus_tag="PC503_001242"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2527251.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            50900..51202
                     /locus_tag="PC503_001243"
     CDS             50900..51202
                     /locus_tag="PC503_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527252.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(51268..52023)
                     /locus_tag="PC503_001244"
     CDS             complement(51268..52023)
                     /locus_tag="PC503_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527253.1"
                     /translation="MGMLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMN
                     NININNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQL
                     LEAILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLP
                     NEIVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETI
                     LIGDIMPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(52011..52973)
                     /locus_tag="PC503_001245"
     CDS             complement(52011..52973)
                     /locus_tag="PC503_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527254.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(52977..53435)
                     /locus_tag="PC503_001246"
     CDS             complement(52977..53435)
                     /locus_tag="PC503_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2527255.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            53791..54147
                     /locus_tag="PC503_001247"
     CDS             53791..54147
                     /locus_tag="PC503_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2527256.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            54219..54935
                     /locus_tag="PC503_001248"
     CDS             54219..54935
                     /locus_tag="PC503_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527257.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            54928..55752
                     /locus_tag="PC503_001249"
     CDS             54928..55752
                     /locus_tag="PC503_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527258.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            55764..56963
                     /locus_tag="PC503_001250"
     CDS             55764..56963
                     /locus_tag="PC503_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527259.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            56972..57784
                     /locus_tag="PC503_001251"
     CDS             56972..57784
                     /locus_tag="PC503_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527260.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            57795..59063
                     /locus_tag="PC503_001252"
     CDS             57795..59063
                     /locus_tag="PC503_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527261.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIIDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
BASE COUNT        23519 a         6086 c        10207 g        19417 t
ORIGIN      
        1 aaattttatt tgataacaaa aattagataa tatgaatata taatgtatgt attaaaaatg
       61 tggcaaatag ttgttttgct atttattatt tgtttaatat ttctaattta taaaaaaaaa
      121 attataaatt ttaaaaatta taaatgacat tttaactaga attaattgta aaaaacacta
      181 tataatactc aattttcaac attctataca attatacaga aattatacag cataataatc
      241 accgaaataa caaattttaa aaattaagca aaactttttg tcgaagttca acgtctatat
      301 atatgtagtg taaatttttg ggataaaata ctacaaaaat ataaatgtaa aaatatagta
      361 atattggagg tcgaacgatg agaaataaaa agaaaaaaat aaatagaaag aagttgtatt
      421 tgcttttaag tgctattgta gtgtgtctgg cttttatagt agttggtgtt cgcgtcagct
      481 ctttaaatat gaaggaaaat gaaattagta gaaatgcaaa actgtcaagt tctactatta
      541 cagatatagt atctaataca tcaatagaag ttagtaaagg gccaagtaaa agttctggaa
      601 aaatagcata cataactata gatgatggtc catctaaatt tactgaccag atgataaaaa
      661 ctttaaataa atacaatgtt aaagcaactt tttttatgat agatgggaat atgaaggaat
      721 atccacagca agttaaaaat ataattaaaa atgggaacac agcaggtttt catagtgtat
      781 cacatgatat tcacaagctt tatgttacta gtacatcagc aaaagaggaa tttgatacaa
      841 atgatcaaac tttttataag ataactggta aacattcaaa agtaataaga ataccttatg
      901 gaagcaaacc atatacacca caagcctctt atcaggcttt agttgatgct ggatataaaa
      961 tttgggactg ggacttagat acagaagact ggagatctaa ttcttctcaa attgtacaaa
     1021 atgtaaaaaa tcatattaag aatagaaaag gtgaagataa agaccaactt gtagttttaa
     1081 tgcatgagaa aaaacagagt gcagaagctt tagattcagt tttaaaattc ttatcagatg
     1141 aaggttatga atttgcgcca gtagatcaaa accaaatacc aaaaaattat tggttacgta
     1201 atttagagta gttaaaatat aagaatattg attgatattt ttagaaattg agaataaaaa
     1261 tgagtgaggt gtaggtatat tgaataaaaa actttatata ggaatggtcg gaatattgtc
     1321 tttgatgatg gttggttgta ataaaagttt agcaaaagta aatgatgtgg aaatcacaaa
     1381 agaacagtac aaaaaaacaa aagcagtttt atctgctact aataattata taaatgggca
     1441 gtctttagat gaattagaaa aaactttgga taaaaaaggt agaaataaat tagaaaatgt
     1501 tataatatcg tttatggtgg ataatgaact tttatatcaa gaggctaagg ataaaggact
     1561 aactccaagt aaaagtgaag tagactcaaa atatcaagaa ctagaagata agatgaattt
     1621 gaatacaagc tataaggaaa aaatggacaa agcaggtgtt gataaagatt atttaaaaca
     1681 agaaatatct agagatttag caatagataa aaataaaaag gcctttgaag atagaataaa
     1741 cataagtgat aatgatatgg aagcctacta tacaagtcat aaaaaagatt ttaatgtaga
     1801 agaagtaagt gcttctcaga tacttatatc gactttagat aaaaataaaa aagaagtaag
     1861 caaagataaa aaagaagctt tgaagaagaa ggcagataat atattgacta aaatcaaaaa
     1921 tggagaaagt tttgaaagtt tggctaaaaa atattcggat gataaagcaa ctggaaaaaa
     1981 tggaggacag ctaggatatt ttacaaagga tgataaaaat gctgagttta caaaggaagt
     2041 gttcaaatta aagaaaaatg aagtttcaaa tgtgtttgaa actagttatg gatatcatat
     2101 agtcaaagtt actgataaaa gagaaagaca aaaaagtttt aatgagtgtc agagtttaat
     2161 aagagaatct attttaaatg aaaagtatat tgagcatata aaaaaactga atgaagatgc
     2221 taaaatagac agatagaatt tctaacagct caatcctagc ctgtaatcgg agggagattt
     2281 tacaggaatg tttaagagtt taaagagaac gaaagttgag aaatacatta tcgataataa
     2341 agactctttt tatagaatag catatagtta tacgaagaat gaagaagatg ccttagatgt
     2401 ggttcaagaa gccatgtata aggcactata ctcagtggaa aatattaaag aagtaaatta
     2461 tataaagaca tggttttata aaattttagt tagaacgagt atagatttta ttagaaaaaa
     2521 ccgtaaatat aataatatga cagatattga ccttatagat gagactggag agtatgataa
     2581 atatactgat ttggatttaa gaagagcttt ggaagaatta cctattgaat acaaatctat
     2641 tataatatta agattttttg aagatttaaa gattgaagaa gtagcaataa tattggatga
     2701 aaatgtgaat actgttaaaa ctaggttata tactgcttta aaaaaactaa aattaaaaat
     2761 tgaagagtag ggataaaaag aatgacaagc aaagaaaggt taaataagtt aaaagatgag
     2821 tatcataaaa ttccaatacc caagaaatta gatactataa taaatcatga aaaaatagaa
     2881 aacatatatc gagagaaaaa taaaaaagta aatagattaa gatttaaagt tgcaatagcc
     2941 tttgcatgta tatttacagt attagtaaat ataagtcctg tatttgcaga caatttttct
     3001 aagatacctg taattggagc aatagtagaa gtaataacta taaaaaatta tagtttaaaa
     3061 agtgaaaatt atgaagctga gattgatatt cctaaaatac gaggtttaaa agataaaaac
     3121 ttagaacaaa gattaaacag tagttttatg gaagatggaa aaaggcttta tcatcaattc
     3181 caagagagaa tggagaagat acaatcatca aagaataaag gatataaatc tttaagtttg
     3241 agttatagtg taaaaaataa ttctaaaaaa tttctatcaa tagagatgac aaaaaatgag
     3301 atagaggctt catcatatgt gagtaaggta cattatacta ttgataaaaa aagacaaata
     3361 gttttgactt tgccaatgct ttttaaagat gataagtata taaaagttat aagtgataat
     3421 ataaaagaac aaatgagaga acaaatgaaa aaggatagta caaaatccta ttttatagat
     3481 caaaaaaaag acttgcctgt tgaagatttt aaaacaatta ataagtatca ggatttttat
     3541 tttaataaaa atgaagacct tgtaatttgt tttgatgaat atgaagtagc acctggttat
     3601 atgggcgcag ttgagtttgt aataccatat aaagtaataa aagatttgta aattgaatag
     3661 tagtttatat ataaatcttt taaggaggac aatatgacta catataaaaa acttaaaaaa
     3721 tctatattta aaattgctat attttcaata tgcttattag cttcattagt agatacaaac
     3781 cctatatttg caggtagttc ctttaatgaa acttcaaata gtgatacgat aaaggtgtta
     3841 aatgctaaga gtatcaactt taaacaagac aattatgaag tgaatgtgag tattcctaaa
     3901 ataaaaggtt taaaagataa aactttagag aataaattaa acaatgagtt tttgcaagat
     3961 gggaaaaaaa tttacagtga atttcaaaat aaaatgaaaa aggaagataa taagggtcat
     4021 agatacctaa atgtaatcca taatgtcaaa aataattcta aggacttttt atcaatagaa
     4081 atgacaaaag aagagataga agcttcctca tctataacta agaagcatta cactgttgat
     4141 aaaaatagag gaatactatt aaatttacca atatttttta aagatagtag atatattaga
     4201 gctataagtg ataatataaa agagcagatg agaaatcaaa ttaagaaaga tgatacaaaa
     4261 tcttatttta tagaccaaga taaagactcg ccagtgaaag attttgaatc tataaataag
     4321 tatcaagatt tttattttaa taaaaatgga aatcttgtga ttagttttga tgaatatgaa
     4381 gtagctcctg gttatatggg agcagtagaa tttgtgatac caaataaagt aataaaaaga
     4441 ctaagataga tatatagaag atttttagat agactggtaa ggagaattat atgaatatat
     4501 atgaacaagc aataagatta atagaaaata atgaggattt cgcatttgct acaataacgt
     4561 ctcattcagg ttcaacacca cgtgaaactg gagcaatgat gattgtgaaa aatgattcta
     4621 ctatatttgg ctcagtagga ggaggtagtg tagaagcaga atgtataaaa catgcaatta
     4681 atgttataaa aaacagagaa tcaatgttgt ataaatttac tctaaacaaa tctgatgttg
     4741 caaaactagg aatgatatgt ggaggtactg gagaaataca aatagatttt atagatagta
     4801 aattaaaaag taatatagaa aaatttaata agagactaaa ggaaaataca agtaaagcat
     4861 atatatttgg tgcaggtcat atttcaagag atgttgctgt gatactatct cttttagaat
     4921 ttagaacagt agtaatagat gatagagaag aatttgctaa tcatgaaagg tttccagaat
     4981 cagaagtagt agttttagat tcttttgaaa acataccaga ttttccaact gacgaaaata
     5041 gttatataat tattttaaca agaggtcatc tatatgattc aagtgcttta gaatgggctc
     5101 ttaaaagaga ggctggttat ataggtatga ttggaagtag aacaaaaatt ggattgactt
     5161 acgaaaaact catgaaaaaa ggttttaaga aggaagaatt atcaaaagta catgcaccaa
     5221 taggcataaa attgaatgct caaacaccag ctgaaatagc tgtatgtata gctgctgaac
     5281 ttataaattg tagagctaat aaggaaaaat aaactaatga acacagggag taaagatatt
     5341 gatactttaa aggttaattt tagagggatt gaaataaaag cagttttagt atataaaaat
     5401 agaaaaaata tttctataaa aatagatcca tttggcaaaa taactgtaat gagtcctcct
     5461 aaaatatcca aaaaaataat aaaagatata attattgaaa aaggagactg gatacttaaa
     5521 aagtcagaaa aatgtaaagg aagagaggaa gtatataaac aaagaatgtt tataactggc
     5581 gaaaaatttc tttatttagg tgaagagtac catttagtta taaaagaact gttgagagat
     5641 tctgtcaaaa aaagtaactg tagaataact attaacgaat atcaaatagt tgttcagaca
     5701 aatgatacaa gtacagattt tattaaaaaa tctttaaaat cttggtataa gatggaaagt
     5761 gaaagaatag tattagagag aatagatttt cttaaattaa attgtgaaat aatgaagcaa
     5821 ttagttccag cgagtgttaa ggtaaaagaa caaaataaga gatggggaag ttgtacagct
     5881 caaaaaaata tttatataaa ctcaaaaata tctatggcaa gattagatgt aattgattat
     5941 gtaataatac atgagtttag ccatttagta catatgaatc actctaaaaa attctatgat
     6001 ttagtaaaat ccattatgcc cgattataaa gataaagaaa attggctaaa aataaatgga
     6061 tataaaataa taatctgaaa acgattattc caaaatatag gcgtaaagta taaaagaagt
     6121 attattgtga aaaaaataaa taatctgaaa attttaaaaa aagtcattga cattgtaaat
     6181 gatagggaat ataatctata ttaacaacaa aacagaatta aaatataaaa ttaaaaaatt
     6241 aaaagcaatg acagagacaa caatactaat agtgttatcc acagagaacc aatgttgctg
     6301 agaattggtg ttaacagtag tataatgatc actctggagc ttttgtactg aatattttta
     6361 gtaagtacaa acgtatgtca gcgttacatg actaaggtta aggtaattaa ttacccgacc
     6421 tgaaaaaaga ggggtagatg tattttttat atctacaaat aaggtggtac cgcggaatat
     6481 aactttcgtc cttataagta atatttatat tgcttataaa gatgaaagtt tttttatttt
     6541 aagcgatata aataaattta atccatataa aattaataaa aaaataataa aaataaggag
     6601 ggatttttat ggaaaatact gtatatgcta aattaaacca aggaatagat tcttttttaa
     6661 gagtggctat gactctaaga agaagagagg ttgatataca atcaataagt atgactgtag
     6721 ataatatgaa taattcaggt ataaaattaa tagtaaatga agaaaagaca tccttagatt
     6781 ctgtcttaaa ccatatgaaa aaactacatg atataagaga gataactgtt gaaagaatga
     6841 gacattaatt aaatatattt tataaagcta aagataaata tgcttatttt aaaataaaaa
     6901 actaaagata aatattaaat aagaaaaatc ttagattaaa atataagtgt cattgaattt
     6961 attagtttat cacagttaat aaatttatta gtttgttgta gctaataaaa actgaaaatt
     7021 ctaaaattat aattgtaaga ttatataaat ttagaattta aatctgttga ataatattaa
     7081 aacaatgata atgagtatga atttctaata aaaataaata tcataaaaat aagaaaaagt
     7141 attgggagga aatgaaaatg gcaagaatgt attatgaaaa agatgtggat ttagaagttt
     7201 taaaaaataa aaaggttgca gttttaggtt atggaagtca aggacatgca catgcacaaa
     7261 atcttagaga taacggtgta catgtagtga taggtcttta tgacggaagt aaatcagcac
     7321 aaaaagcaaa agaagatgga tttgaagtta agagtgtagc agaagctaca aaagaaagtg
     7381 atttgacaat gatgttaatg cctgatgaaa aacaaaagaa agtttatgaa gagagtgtaa
     7441 aggataactt aaaagaaggc cagacattag cttttgctca tggattcaat atacattata
     7501 atcaagtaca accaccagaa tttgttgatg ttgtaatggt agctcctaaa ggacctggtc
     7561 acttagttag aaatgtattt acaaagggaa gtggagttcc tgcactattt gcagtatatc
     7621 aagactacac taaaaaagct acagagacag ttttagcata tgcaaaaggg ataggagcaa
     7681 caagagcagg tgttttagaa actactttta aagaagaaac agaaacagat ttatttggag
     7741 aacaatcagt actttgtggt ggaataagtg aacttataaa attgggatat aaaacgcttg
     7801 tagatgcagg ttatcaaaaa gaagtagcat attttgaatg tttacatgaa atgaaactaa
     7861 tagtcgacct tatatatgaa ggtggatttg aaagaatgag atatagtata agtgacacag
     7921 cagaatatgg agattatgta tctggtaaaa gggtaataac tgatgttgca aaacaaggta
     7981 tgcaaaatgt tttagaggat atacaaaatg gaaaatttgc aaaagcgtgg attaaagaaa
     8041 atgaagaagg acgtgaaaac ttcctaaaaa ctagagaaga agaatataat acagaaattg
     8101 ccgaagttgg tagaaatcta agaagtatga tgtcattctt aaaataaata tatattaaat
     8161 ggattagttt gagggaaaga gtggtgtata gtagtgcgta tgaatggagc aaaggtaatt
     8221 ttagaatgtt taaagaaaga gggaattgac acaatatttg gatatcctgg tggagccgtg
     8281 atacctcttt atgatgctct atacgattat tcagatgatt ttaaacatat aaggacatcc
     8341 catgaacaag gtttagttca tgctgcagat gggtacgcaa gaagtactaa tacagtagga
     8401 gtttgtttta caacatctgg tccaggagca acaaatgcca taactggaat agcaacagct
     8461 tttatggatt cttcacctat ggttgtaatt tcagggcagg tgccaactag tttattagga
     8521 aaagattctt ttcaagaaat tgacataact ggagcaacat tatctatgac aaaacataat
     8581 tatttagtta gaaacactaa agaattagtt cctacaataa aagaagcttt tagagttgca
     8641 aattcaggta gaaaaggacc tgtacttgta gatgttccaa aagatttatt tttagcagaa
     8701 atggatttta gtggtgagga ctatgattta tgtcaaatag atgattatat ggattataag
     8761 agtgattttg atctagatga tgaaactaat attaagcttt taaatgaagc aatagatatc
     8821 ataaaagaat ctaaaaagcc tataatatat gcaggtggag gtgttaaatc ttcagacagt
     8881 gaggaaattc ttgaaaaatt tgcaactaag atagatacac ccgtactaaa tacacttatg
     8941 gggcttggaa atatagatag aaagaatgaa ttatctcttg gaatggttgg aatgcatgga
     9001 agtagagaaa gtaatttagc actttctaat tcagatttag taatagcgat aggtgcgaga
     9061 tttagtgata gagtgataag taaaagttct gaatttgcta aaaatgcaaa aataatacac
     9121 atagacatag acccatctga aataagtaaa aatatagaat ctaatgtatc tttggttgga
     9181 gatgtaaagc tagtccttag tttattaatt gaaagggttg aaagtaagaa taatagcaat
     9241 tggaaagaag agataaagag atttagaaag agtgagggtg tacaaacata tgaatttcat
     9301 ccacaaaata tacttaaaaa aataaatgaa aaatatgaaa cattaaagaa acccactgtg
     9361 gtagtaactg atgtcggtca acatcaaatg tgggctgcta agtactggaa ttttaaaggt
     9421 aataaaagtt ttataacatc agcagggtta ggaactatgg gatttggttt aggtgcagct
     9481 attggaacta aagttggtaa tgtagataaa aatgtggttt tagtcactgg tgatggaagt
     9541 tttagaatga actgtaatga actagctaca gttgcaaatt ataatgtacc tatgcttatt
     9601 ttactactca ataatagaac attaggaatg gtaaggcaat ggcaaaagtt attttccaat
     9661 caaagatact ctcaaactga cattaatgaa aatgtggatt atgttaaact cgtaaatgca
     9721 tataacattg atggatataa ggtatccagt atggaagaat taggaaaggc gctagatatg
     9781 atagatttta ataaacctgt atttttgcaa tgtgatatag ataaggatta tgatgtttat
     9841 cctattgtag cacctaatga tgcattggaa aatttgatat gtaactaaaa cttatactga
     9901 atattgataa aattttttat taaattttta ttagtattca gtttttgttg tttagagata
     9961 gattggcatt ttttattttt gcaaataaat caatgactat ataattaaga acttattaaa
    10021 ttttaattat acaatttaga atagtattac aacttaagta aataataatt ttgaataata
    10081 atttacggag gtattcatat gtttaaacac gataaagcat tattaaaaga agtaaaagta
    10141 gaaagaccaa atcctcaata tgctgtttta atgcaagaac agttgggtgg tgcaaatgga
    10201 gagttaaaag cagctatgca atacttgtcc caaagtttta gaataaaaga ccctcaaata
    10261 aaagatttat ttcttgatat agcagcagaa gagcttagcc atatggaaat ggtagcacaa
    10321 actataaatt tattaaatgg acatgatgtt gattataatg cagttaatac aggcgaaata
    10381 gaaacacatg tattaactgg tctatcacca gtcttaataa actcatcagg agctccttgg
    10441 actgctaatt acgttacagt tacaggggat ttagtagctg acttactttc aaatatagct
    10501 tctgaacaaa gagctaaggt agtttatgag tacttgtata gacaaataga tgataaatat
    10561 gtaaaagaaa caatagattt cttacttaat agagaagaag cacataatgc tctatttaga
    10621 gatgctttaa ataaagttaa agatacaggt tcaaatagag attttggagt tacagaagat
    10681 tctaaattat atttcgattt gtctactcca gggccaaatc acgatactaa gatagatatt
    10741 aatcctcctt cttttgaaaa acctttaaaa aaataatttg atatttttta ttttgtttta
    10801 gtagttataa aaattattta ctagaagaat taattatatg aaaaattaaa tatgtatagt
    10861 taaaaatggg tatacactta ttataagtgt atatctattt gtttattgca aaacatataa
    10921 taaaataaca aatgaggtgg tattttggac agtaatagaa aacctaataa tctaataaat
    10981 gaaaaatctc catatctttt acagcatgct tataatccta taaactggta tagttggaat
    11041 gatgaggctt ttaaaaaagc aaaagaagag gataaaccaa tatttttaag tgtaggatat
    11101 tcaacatgtc attggtgcca tgttatggaa aaagaatctt ttgaagatga agaagttgct
    11161 gaaataatga atagaaactt tgtggcaata aaagtagata aagaggaaag acctgatgta
    11221 gatagtgtgt atatgacagt ttgccaagct atgacaggta gtggtggatg gccaatgacc
    11281 ataataatga caccagataa aaaacctttt tttgcgggaa catatttccc aaaatattca
    11341 aggtataata gacctggagt tatagattta ttagagaatg tatctgaaaa gtggaataca
    11401 agcagagata tattaataaa atctggagat gaaataatag aagctcttaa ggatgatttt
    11461 ggtgtaaaaa atactgaggg tgatttatca aaagagatgt tgagttcatc agttagagta
    11521 tttaaggcta tttatgatga aaagtatggt ggttttggta atgctcctaa atttccaagt
    11581 cctcagaatc ttatgttttt aatgaaatat tatagtatag aaaaagacaa agatgtgtta
    11641 aaaatggtgg aaaaaacttt agatggaatg tatagaggag gcttgtttga tcatattgga
    11701 tttgggtttt caagatactc tactgataaa aagtggttgg ctcctcattt tgaaaaaatg
    11761 ctatatgata atgctatgct tactatagct tttttagatg cgtataaaat aacaaagaaa
    11821 gagttgtata aagaaattgc tataaaaact atagattatg tagttagaga gatgaaggat
    11881 aaagaaggtg ggttttattc agcacaggat gctgatagtg aaggtgaaga aggtaaattt
    11941 tatacattta atcctcttga gataattgaa gttttgggtg aagaagatgg aattttcttt
    12001 aataattatt ttgatataac tagtagtgga aattttgaag gcaaaagtat tcctaatctt
    12061 ataaaaaata aagaatatga gagacataat gaaaagatag ctgaccttag taaaaaggta
    12121 tttgaatata gaaaagaaag aacatctttg cataaagatg acaagatact tacatcatgg
    12181 aatgcattga tgatagttgc tttaacaaag gcatatagta ctttaaaaaa tgacatatat
    12241 ttagagtatt caaataagtg tcttaacttt ataaataata atcttgtaaa tgagtcaggt
    12301 agattattag ctagatatag agatggaagt tccgactatt tagcatattt agatgattat
    12361 gcttttttaa tctgggcgta tatagagctt tatgagtcaa catttaatat gaaatattta
    12421 gaaaaggctt taaatttgaa tgaaagctgt atcaaccttt tttgggatta tgaaaaaagt
    12481 ggattttata tatatggtaa agatagtgaa aatttaatag caaggccaaa agatttgtat
    12541 gatggagcta ttccatcagg aaattctgtt caattataca atcttataag acttgcgaaa
    12601 attactggag ataatagact tgaagaaatg tcatataaac aattaaaact gtatgtggat
    12661 aatgtaaaga gttctccagc tggctacagc ttttatatgc tttcattgat gtttgaactt
    12721 tattctacta aggaaattat atgtattttt aaggaagatt ctgatttaat tgcctttaaa
    12781 gaattgataa gtgaaaattt tataccaaat gcaacttttt tagcaaagaa atacaatgaa
    12841 gaaaacacta ttataggttt tttaaataac tatagattga aggatgataa gattagttat
    12901 tacgtgtgtc aaagtaatag ttgtagtcaa ccaattaatg atttacaaaa attaaaagat
    12961 atgattttag gagtagaata atcataatag tgaaaaagga gatgctttaa aataaaagtc
    13021 taatcatctc ctttttttgt acaaaaaaca gaaaaagagt tcctgagaac acctaatcta
    13081 tgtaatgatt gttttgttaa aaaataaaaa tgacattata gttatataaa atattgtact
    13141 ataaaaaagt agtattatag atgcgatagt attaatcgtt tttatttact ctctttcttc
    13201 tttttgcaaa ttcttcaagt gcttcagatt taattttatc tatttcttca tattccataa
    13261 aattagcatc ttcttcaaag ccatcttgtt cttcaccatt aaaacgatac atttttttta
    13321 gtaaactcca taaggtctct aattcatctt tggtaaattc gtgaaataca tctgccataa
    13381 agtttattcc agtcctacta catgttacca taaccttttt tcctaagtct gtaactttaa
    13441 cattaattgc tctcttatca tgaggacttg gaattacatc aacatatcca tttttttcaa
    13501 gattagcaac tagtctattt atattttgtt tacttgtacc catttttctt gcaatattat
    13561 ttaatgttgt ttcttcctct ggtaaatgaa gaattgataa aatagtcata tactgtcttg
    13621 aagtaagtat accaaaatat ttatctcctt ctatttgtat tttgtttgta agggtaaaaa
    13681 gagttgcata tgtttgattc attaaaaaga gttcttttag ttcatttgaa taatccatga
    13741 aatatatctc ctttattttt agatgttgtt ttgtcgaaaa cagaatatca tgaattaatt
    13801 ctaatgtcaa tatggtgtca aaatatatta aagtattact tttttatgta actattaatt
    13861 aattaaatta ttgtataatt ttatgtaaaa acttctatgt accaatgata acttctatga
    13921 ggaattaata attcttaaat tttttagaaa gattttgact tgaaaatact tgtaatataa
    13981 tatataaatt aatatactga ataaaatcaa tctggaggga taattatgaa gtgtacaaac
    14041 tttactttca aaggagagga aggtttagat atatatacat ataaatggga agatgaaaat
    14101 ataaaaaaac caaaggcagt tatccaaatt gcacatggaa tggctgaaac tgcacaaagg
    14161 tatgagactt ttgccaaggt acttactaaa aatggttata tagtatatat caatgaccat
    14221 agaggtcatg ggaaaactgc aaagataata gaaaatgttg gacatttagc tgaaaaagaa
    14281 ggatttagat gtcttgtaga ggacatgtat actttaacaa atattataaa gaaagaaaat
    14341 gaagatctgc caatttatct atttggacac agcatgggtt catttgcaag tcaaagatat
    14401 ataatggatt acagtaataa tttatctggt cttatactat gtggttcaaa tggaaagcaa
    14461 ggaatcattc taaatcttgc tcatctgata atcaatcgtg agattaaaaa gtatggaaga
    14521 cgttctaaaa gtaataaaat aaataatttg atatttggcg gcgaaataat aagaagaaat
    14581 gaaaagacta agtttgactg gttaagtaga gataaagaac aagttgaaaa atatataaat
    14641 gacccatttt gtggagtagt gtgtagttgt ggcttttttt atgatttagt tcaagggtta
    14701 aaagaaattg aggataaaga aaacttaaaa aaagtgccac ttgatatacc tatttacata
    14761 atatctggag ataaagaccc cataggaaaa aatggtaaag gagtcttaag actaagggat
    14821 agatatataa aattaggagt aaaagatgta acttgcaaac tttacaaaga tggaaggcat
    14881 gaattgttga atgaaataaa tagagaagaa gtttttgagg atataatttg ttggttaaat
    14941 aataaaatag aaatattgta ataaaaaaat ataatgatat atttacttta aatttattta
    15001 tatataatat ttgaaaagtg gattatgtat atgcaaagta gaaaagagag agcccagaag
    15061 tgattttttg ctataatgcc atttattgaa taggtgggtg ttattataaa taaattatta
    15121 acactcagta ttattatcat tgtatatgga atttatttta tttaaaattc cttgaaagtt
    15181 taaatatagt aagttgtagt aaagagaaaa tataaatatt taaatgctat ttaatgtgaa
    15241 tctattaatt aggttatact taaacttaat taatagattt tatatttcaa gacaatgaga
    15301 tagggtttta gattaaaata taaccaatgg ttaaattaca gacattttgt taactttccc
    15361 tcgatttact agtaaatatt ttttttatat acttaaatta caacagatgt actagggagg
    15421 tatatatgca aattaaaata ggtaaagtca tacagtgtct tagaaaagaa cgaaatttaa
    15481 ctcaagaaca attagcaaag tttataggtg tgtcaacacc agcagtatct aagtgggaga
    15541 gtggaaattc ttacccagat atagaattat tgcctttatt agcagacttt tttaatgtgt
    15601 ctattgataa gcttttaaat tacaagattg atttaagtga agaagaagta atgaaaattt
    15661 ataaagaatt agaatcaggc tttgctagaa ttgaaattga tttatcaaca gaagaaccaa
    15721 aagaagaatt tagacaagat ttagaatctg taaaaaagct ttccaatatg tatatagaga
    15781 agtatcctaa aagctattta ttgaagctaa ggatatgttc gctgtatcag atgtattcat
    15841 ataaatttgg taagagtgaa cttaatgaca gagtaaaaga aacaacgaat attcttgaag
    15901 atatagtgag aaatacagat gatatccaaa taaaagaaac agctcttatt atattatcaa
    15961 acgcatattg tatgttggag gattatgaaa aggcagagtt gtatttaaat atgatacata
    16021 agtcaatagg ggatacaagt gttaatttag ctatgatata tttaaagcaa aatagacttg
    16081 aagaagcaga aatattgctt caaaataaat tgtttagtaa tgtatttaat ataagcatgg
    16141 attgtaaggg aataattaat gtatacaaaa atcaatacaa ggaattaaag aaaaaattgg
    16201 agaatagaaa ttttaataaa aatgcaattg agagagaaat ggagtatata aaaaataagt
    16261 tgctggggta tgcaaatctt tctttagaaa taaaaaaaat gctcagtgaa gataaaggtg
    16321 cattttttag tatgtatatg gattatatgg aattatctct aattttttta ttttttaaca
    16381 tgaaagaaga agcaaaaaaa gctttatata gtctaaaaga aatattagaa aaatatccta
    16441 tacatgaaag tttggatgta agtcaaatga gattttttga taaggtagag tctaaaaatt
    16501 tatatacttt taatatatat acaaacttgt taattgtact taatgatgac agttataatg
    16561 agcttagaga agaaccaatt tttaaggatg taattgaaaa gattttagat atggaaaaaa
    16621 tgttgaaaaa taaagaataa gtaaaaattt aatataggac ttaaagatta atcaaattaa
    16681 aagaaagtgt ttcaaaataa aaatttgaat cacctttttt gtcggtctta aacagttatt
    16741 tagaaaaata gaggtttcaa aatagaaatc tgaattatct gtattattac acaaaaatag
    16801 aaacctaaat ttataaaaat agaataaaat ttgttatata aaatgtaatt ttgtctataa
    16861 aatctcacct gttttcttaa ctttaagcgt gaaaaagagg atgtatcatg aattttttag
    16921 ttcatgatgc atcctgcttt gtatgaaatc caatatatct ttattattta aacaatggaa
    16981 aagagtctta tttatatttt gagacatctc ttttatttaa ttatgaagtt ttatacagtt
    17041 caataaatag gaattatatt tagaaactca tgacattatt tcttagatag tgattaaatt
    17101 tatcatattc cattttagat aacttttctg ggtaagacat tacaatcagg ttatgcccat
    17161 taaatttttt atggtatggt ggatgaatgt gttcataatt atttgtctta tattttactc
    17221 tttcatagaa cgccttgcga taaattgaaa tctcatcaat tggaaggtca atttctaaaa
    17281 taatagtttt tcctttctta tttaaaagct ctaacgctct ttgcccatat ctattattgc
    17341 gaatttctgg aaaaatgcag aaatgttcta catagataaa gttatctgtt tcccaacata
    17401 aaattatgcc gacaaactgg tttttatcat aaattaaatt gaattgatat tctttatttt
    17461 tcaaaatttc tgcttgcaaa gaagattttc tttgtttatg aaatgggaaa ctaattttat
    17521 ataattccat agccttgtaa tataatttat tttcactggt tcttaaccgt tcaaatttca
    17581 ctttactcct cctaatcacg aaaattccaa tttatttatg agttcatttt accatagtca
    17641 gtatttgcat acaatgtgtt ttaagttgag tgtcatttct ttcttttatt tatgcttata
    17701 tctcatagtc taagagataa ttgcttaaga cataactaaa aactattata ttaagctttg
    17761 ataatctaaa aacagtatat ttatggactt ttctaggtct aaaagtaatc ttaataattt
    17821 tagaagttac aaaaaagtta cataaatttg gaaagctata atatacatat ataatataag
    17881 gttaaaactg taatgaataa tattaattta aaatttgaac atggaaggag attattatgg
    17941 agaaaagaga aaagaggata ataatatcat ctttattaag tgtatcaatt ttaatgggtt
    18001 tggcaagtat atattctata ttaaataaag aagacataag tttaaccgtt aaaggtcaag
    18061 agcaaaaagt atcttccttt aagaaaacag ttgaggaact tttggatgaa cagggtgtaa
    18121 agtataattc tgaagataag attaatccaa gtttagatac agagttaaaa gatgatatga
    18181 aaataaaagt tgttaaggta actaaaagta aaaaagaaga gattgaaaaa attccatttg
    18241 atacaaagca tgtaaatgat agtaatttgt taaaaggaaa atctaaagtt tatcaagaag
    18301 gtcaagaagg agaaaaaaaa ctagtctata atttaactta ccatgatggc aagttagtca
    18361 aaaaagtctt atcaaaagaa gtaatatcta aggagccaac tacaaaaatt ataaaatatg
    18421 gaactaaaga aaaagtacta atagcatcaa gaggagcaaa tataagagga ggcaaacata
    18481 tgaaagtggt tgccactgca tatgcaggag atacaataac atctactggt acaactccaa
    18541 gatggggtgt tattgcagtt gacccacgtg taataccata tggaacaaaa gtatatatac
    18601 ctaaactggg tatgactttt gtagcagaag attgtggagg tgcaattaaa ggtaatagaa
    18661 tagacatttt tatgaacagt gaaggaaaag cttcaaattg gggaaggaaa agtatagata
    18721 tatatctaca ttaaattagt gaatagaata actttacttg aaggacaaaa aagtataaaa
    18781 tatgaattaa ctaaactgtt agattattct taaaacataa aaatatatct aaggggggat
    18841 aagatgaaaa tagtctgctt aggagacagt ttaacgtatg gatttggagt atcacgaagt
    18901 aattcatgga caaacattgt aaataaagag actcgattag aaatagtaaa taagggtata
    18961 aatggtgata caacaagtgg tatgttagct aggtttaatg aagatgttgt aaaaaactct
    19021 cctgatatag tttttataat gggtggcacc aatgatttta ttgctggtgc gggaaatgaa
    19081 attattaatt ctaatataat ggctatggtg catcagtcat attcaaaaaa tattatacct
    19141 ataataggta taccattaaa accagatatt ccaaatgtta gggaagattg gagttgtttt
    19201 actgatttta atatagtatc tcaaaactta gaatcatata gttattggat aaaaaaattt
    19261 tgtatgacat ttaatactaa tttcgtagat ttttattcag aatataataa aaatatggaa
    19321 ctagaaggat ataaaaaatt atattttgat gggttacatc caaccaaaga gggtcataga
    19381 ataatggcag acatttttat taattcaatt aataagtata tagaagagtt atagattaca
    19441 ttaaaatgct tgtttatgcg tcagttgcaa taaatacata cagtagagag gggtttatta
    19501 tggattatac taaaacttat gaagagtgga taaagggttc atattttgat gaagatacaa
    19561 agctagagtt ggagaatata aaaaataatg aaaaagaaat agaggataga ttctataagg
    19621 atttagaatt tgggactgcg ggtcttagag gaataattga agcaggaacg aatagaataa
    19681 ataagtacac agttagaaga gctacttttg gattggcaaa ctatatatta gaaaacacaa
    19741 caaaagaaga aacaagtaga ggagtagtaa tagctcatga taatagacac aagtctagac
    19801 aattctgtat agaatctgca aatactttgg cagcatgtgg tataaaagca tatatatttg
    19861 atagtttgag aactactcca gaattatctt ttgctgttag aagcttaaat gcaatcgctg
    19921 gtatagtcat aacagcaagc cataatcctc cagaatataa tggatataag gtatactggg
    19981 aagatggagc acaagttatg ccagagattg caaatgcaat aacagagaaa gtaaatagta
    20041 tacatgatta tagtacaata ccaaccttaa cggaagctaa taaaaatttg gtagttttgt
    20101 tggacgaatc acaagatact aaatttatag aagcagtaaa aagccaaatt ataagaaaag
    20161 atttagttaa aaatgtaggt aaaagcttta agatagttta tacacctctt tgtggaacag
    20221 ggaatgttcc aataagaaga gcattgaaag aagttggttt tgaaaatata attgtagttc
    20281 cagaagaaga aaatccagac ccaaattttg cagggcttga ttatccaaat ccagaagaga
    20341 aaaaagcttt aaatagaggt atattactcg caaaagaaaa aggagcagac cttgtaatag
    20401 caactgaccc agattgtgat agagtaggtg tagcagtaaa aactactaca ggtgagtatg
    20461 ctttacttac aggaaatcaa attggtggta tgctgacaca ttatataata gaaggattaa
    20521 aagaaaataa taaattaaaa gaaaatccta caataataaa aaccatagtt acatcagaat
    20581 ttggagcaga tatagctaaa gcaaataatg ttgatgtatt aaatgttctt acaggtttta
    20641 aatttattgg tgaaaaaata aaattatttg aacaaaataa aaatagaagt tatgtatttg
    20701 gatatgaaga aagttatggt tacttagttg ggactcatgc tagagataaa gatggtgtag
    20761 tttcttcatt gttaatatct gaaatggcag cattttacta ttcaaaaggt atgagtttat
    20821 atgatggctt aatagaactt tataaaaagt atggattttt caaagaacag actatatctt
    20881 tgactttaaa aggtatagaa ggtgtagaaa agataaaaga aataatatct tattttagag
    20941 aaaatcaaat tgattatata aatagtatta aagtagttga taaaaaagat tataaaaatg
    21001 gtatagataa tcttcctaaa tctgatgttt taaaatactt tttggaagat gaatcttggg
    21061 tagctataag accatctgga acagaaccaa aacttaaatt ttacatagct gtaaaaggag
    21121 ctagtgatat tgaagcagat aaaaagattc aaggtttgaa aaagtatata gatgacatgg
    21181 tcgaaaaatt aaaataaaat attattattt tataagataa ttttgtaata atatttattt
    21241 agctgaaaat tataatttac tttcattgag tagaatatgg aaatgttagt agaattgtta
    21301 ttttcagctt ttatttgtgt tatttttact taaataatta tattatagaa tgaatctgag
    21361 tataattaat attgtataat gaaattaatt tgatagaaaa ggggatattt atgtttggta
    21421 tagataagaa attgattgaa tatataattg caaaatccaa ttacagtgaa ttaagttcaa
    21481 agtcagcaga agtatctttc ttcttaatgt tgtccatatt tcctttttta atatttacaa
    21541 taagttctat agcttatata ccgattcttc atttaaataa gtatatagct ttgtttagaa
    21601 atatgatgcc agaaggtgct tttgctgtgt tatcttcaat catagtttct gcaatagaca
    21661 atagaaacct gaaattttta gcagtcagtt ttgtacttac tatgtggaca ttttcaagag
    21721 cagtaaaagc tcttattaaa ggaatgaata gagcctataa agttaaagaa actaggtctt
    21781 tttttaaaat tttatctata tcatttttat ttacaataat gcttttggtc cttatttttt
    21841 tatctatgat atttttagtt tatggggaaa aaataggtta ttttattttt aatcttgtag
    21901 gattggatga gatatttata aaaatatggg atattctaag atacactgta ggtataataa
    21961 caataatagt gatatttaca cttttatata aatacactcc aaataaaaag ttaactatta
    22021 aagaatctgc gccaggtgct atttttgcta cttttgcttg gtttttagta tcatttttat
    22081 attcttatta tacaaattac tatgctaact atgaagtaat ctatggaagt atagctgaaa
    22141 taattgtact tatgacctgg atgtatttta gtagttggtc tatcgttatt ggctatgagg
    22201 taaattcaag attgtatttt agaaagataa gacatgaaat gttaaagtaa agtatttaaa
    22261 ataaaagaga gtatttagta ttataaatgt aattgaatta ataaagaaat attgacattt
    22321 aagttaaaaa gtctagaatt tttctgggct ttttttattt ttagtataac ttgacaaatt
    22381 ttatttaatg ggatagtttt aatttataat catctttaaa aagatgacta ttgataagta
    22441 agagataaaa ttggtaagta tcaaaaaata tactaaataa aaattatagt cctaatgagt
    22501 taatttctgt attttcaaat aatgcagtat ttagtcatgt gtttttatat gcgcctgtat
    22561 ttctaattac caatatatta gaataagcta ctgtaattag atttagaaaa aagcgacata
    22621 aataattata aacaaataat aaattacata aaattaaatt tattcacaag tatatcttat
    22681 aaaatatgtt ataattaata gaaaattgtc atataattaa ttaagtagta ttattataaa
    22741 taacattgaa aggtagtggt tagaatatgg atacccataa taaatatgta aattttataa
    22801 aaaatatacc tgtacctttt ttatattgta gaattgtaaa gagacaagaa gatatagaat
    22861 atcgagtaga atatataagt aagggtatgg gcaaagtatt acaattagaa gaaggtattt
    22921 gtgataaaaa tatactagat gtattgcctg tatttaagtc taaaaaatat ttcaaagagt
    22981 tgttctcaaa tgaagtggat tgtataaaaa ggtacattcc gacacttaaa aattggataa
    23041 atataaaaaa acagataata ggggattcat acataatttt gtattttggt aaaattgtat
    23101 ttgattatag acagataatc gattcctttg ataaaaagga aaaagtagct tatattaaag
    23161 acgaagaagg cacatatata gattgcagtg aaaatttaat accaatatta aataacaaca
    23221 ttaaaacaac gaaagatatc tttggtaaaa atgatataga agtatgggga gagaatacag
    23281 gaaaattatt tagagatgat tatagagaag gagtatctag taaaaaaaga tttttacaaa
    23341 atctttttga atatgaagaa acatttttta tggttgaaaa atattttttg tatgatgaag
    23401 acgaactttt aggtactata gggatagtag acaatataat atatagtggt tacagtaata
    23461 gaaattataa ctcaaaagat ttaatgaaga tgatagaaca ctcaattcca gagaatatgt
    23521 tttataaaga tgtgtatgga aattatattg gatttaattc aggttttttg aatttagctt
    23581 gtatgaataa agaagaatta ttagggaaga atagttataa aatatcagaa gaagaagctt
    23641 taatagataa gatatttgaa agtgataagg gtgtagttga aaataaaaaa gtagttacat
    23701 ttgagttaaa tataagtatg aatgatgaaa acaagtgtat tgagattaca aaaaggccgt
    23761 tttttgatag ctatggaagt gttattggaa taattggaac agcaagggat ataagtagaa
    23821 gaaaaagatt agaagaggaa atggataaaa ctaggatgga attttttgca aatttatccc
    23881 atgaacttag aacgcctata aacttaatat catcttcatt acaagtgata gaaaaaaaag
    23941 aagcagattt aatagaatca aatgatactt taaaaagaaa tttaggtata ataaaacaaa
    24001 atggaaatag aatattaaga ttagtaaata atgttataga ttttacaaaa atgcaatcag
    24061 gatatttaga ttttaaacca gaagaatctg atataattgc atttatagag gagatatgta
    24121 tgtctgtagc tgattttgca agccaaaata atatacaact tacatttgat acagaaatag
    24181 aagaattttc aatgttattt gattcagaaa aattggaaag aataatatta aatttacttt
    24241 ctaatggaat taagtacaat aagaaagatg gaaaaataaa tatattttta tatgtgaaag
    24301 ataatgtatt taatatgaaa atatctgata gtggaatagg aataccaaaa gaaaaaatag
    24361 ataaaatatt taataggttt gaacagattg acaatgaact ttcttacaga gttaaaggaa
    24421 gtggtattgg actttcatta gtgaaatctt tggttgagtt gcatgaggga agtatatctt
    24481 taaaaagtca acttggtatt ggaagtgaat ttatagtttc attgcctgtt agaagtaaaa
    24541 ataatattga aaaatataat cataaaagag aaatcagcaa tgaattaagt aaaaaattag
    24601 aaatagagtt ctcggattta taagtttaaa tataaaaaat aaaattttaa aaaagtattg
    24661 acaattgatt tagaagggtt taaaataaat tacaacataa taaataaaaa ggcgatgaat
    24721 aggaagagta aatctaattc gattaccaga gagaagagtc cgttggctgg aagacttttt
    24781 aaattagagg gattgaaaac tacctaggag ctactttctg aagtcatctg cattagtaga
    24841 ttttagtaag aatagtcgtt agctgcgtta aagtgtaaag tgagttttca tgacatatga
    24901 aaactaaatt aggtggaacc gcgggaataa tactctcgtc cttatgttat aaggatgaga
    24961 gttttttgtt atttaaaaat ataaacagta atcataataa ttatagaaaa tataaaagca
    25021 atgaatagga agagtaaatt taattcgact atcagagagg aaagttcaca ggctgaaaga
    25081 ctttctaagt ttgagaaatt gaaaactacc taggagctgt ggtctgaagt tactttaaaa
    25141 agttttagta agactaaccg ttaactgcgt taaagtgtaa agtggatttt atcaataaat
    25201 gataaaatca aattgggtgg aaccgcgagt atagactcgt ccctttatat agggatgagt
    25261 ctatttttat tgcaataaaa gattgaaaat aaaaaaaaat cggaaaatta taaatttagg
    25321 aggaaaataa aatggagaat aaagtgaaaa ttggagtact aggatatgga gttgtaggaa
    25381 gtggacttat agatataata gataataata aagaaaaaag aaatatagaa atagttggaa
    25441 ttttagttaa taatttggaa aaacataagg ataaaaaata ttctaatata ataactaata
    25501 atatagatga tatatttaat aaagatatag atatacttgt tgaagtcatg ggtggtttag
    25561 aaccatcatt atcttatata aaaaaagcat taaacaataa aattcatgtt gttacagcaa
    25621 ataaagattt gttagctgaa tgtggagatg agcttgcaaa attagcaagt gaaaataaag
    25681 taagtattaa atttgaagct tcagttgcag gaggtatacc agtattaaaa ccaataatag
    25741 aatcactaga aggaaataat atagatagta taaatgcaat tttaaatgga actactaatt
    25801 ttatattatc taaaatgtat gatgagaatc tatcttatga tatggcatta agacaagcac
    25861 aagaattagg ttttgctgaa gcaaatccag agtcagatgt attagggtat gatgctgcta
    25921 gaaaactatc aatattatca actctagctt atgacaatag agtatattgg aaagatgtgt
    25981 atttagaagg aattacagat atagatgaaa aagatattga atatgcaaaa aaattaaatt
    26041 gtaaaataaa attgattggt caaagtaagt atgaaaatga taaagtaagt gcttttgtta
    26101 gacctgtttt agtagaaaaa gataatatcc ttgctagaat agacaatgag ttcaatgctg
    26161 tcatagtgaa tggagattca gtaggagaag tttcttttgt aggtaaagga gctggaagtt
    26221 tagcaacagg aagtgcggtt tattcagatg ttatagatat aatagataat agagtttcaa
    26281 gtatagattc ttttactaaa gataaaatac aagttaataa aatagttaga gaaaagtgtg
    26341 gagcacttct tagatttaaa aaatgtaata aagatgaaat tctaaatata gttgagaatt
    26401 gtttagtaaa attcgatatt ttaaatgatg atgatgaact tgctattatg gtttatgctg
    26461 attctgaata tgaaataaac aacagtttat gtctaataaa agataaagga tactgcgaaa
    26521 aaatgaataa aatgttgaaa ataagttaaa aaagaaaaaa tataagttta tatgtaacat
    26581 attttgacga ttttaatact atatagtatg agatgaaaca aaacatctca taaaaaaatt
    26641 aaaattaaag ggagagatat gttatatgga aaataaaaaa tgttattcag aagattggta
    26701 tgaaagagga gaatctacag ctaaatggtt ccaaaatgat agagaagaat atgaaagaga
    26761 agcatatgat gaagatagag aaagaagagg ttcaaactgt ggatgttcag attcaggaga
    26821 aaatagacct agaaactgtg aaagatttag aagagaagct gagataagag aaagagaagc
    26881 aagagaagca ttctgtgaat cttcagagaa aaagaaagag gcattagcat atgaatgtga
    26941 agctagaaaa ttatgggaag aagcagaaaa atactgggat gaatattcaa aatacaacta
    27001 taaaggaatc gaatatttag cagaagctgc tagattattt gatgaaggta tggaatgtga
    27061 agctagaaga aatggaaata atggaggaaa caataataat tgttgccata aatgccataa
    27121 atgtaattgt aactgctgta gaaaataaaa aaattaattg acaaatcaat agttaaaata
    27181 tatcatatta tgtataataa agagaaaatt cagaaaaaaa taatgattag aagaaatata
    27241 agtatattta ttagacaaat agtgctcagt tagtgaggtg agtacaatat gattaaactc
    27301 ccatcctcta gcttttgata gagggtggga gtttttattt atttatatat cttaaatgag
    27361 gataatattg taaaataaat gagtatgaga ttgtaaaatt aggaggtaaa aatgaaaagt
    27421 attaaaacat caagtatgaa agaaaaggta gatgaaaaga tattaagaga gcaagtaagt
    27481 tctataatag aagatataag aaataataag gatgttgcac ttaaaaaata taatgagaag
    27541 tttgatagaa atacaagaga tgaatttaga attactaagg aagaaataaa ggaagcttat
    27601 aagcatgtag atgacgaatt tataaataac ttaaagattg ctgccaaaaa tataagagaa
    27661 tttgctaaag ctcaaaaact aagttttgaa aacccttttg aaaaagaaat ttatccaggt
    27721 gtaatcttag gtcaaactaa tattccaata gagtcatgtc ttgcatatgt tccaggaggt
    27781 cagtatccat tgttttcaac agctcttatg cttataatac ctgcaaaagt agcaggagta
    27841 aaaagaatag tggcatgttc accaactatg aaaaatactg aaaagataaa tcctaagaca
    27901 ttggtagcta tggatatagc aggtgctgat gaaatatatg caactggagg agttcaagct
    27961 atagcagcat ttacatatgg aacagaaaag attaatccag ttgacataat tgtaggacca
    28021 ggaaataagt ttgtaactga agctaaaaga caatgttatg gacaagtagg gattgatttt
    28081 gtcgctgggc caagtgaagt tcttataata gcggatgaaa cttcaaatcc agtttatatt
    28141 gcagctgatt tattagcaca atgtgagcat gatttaaatg caagaggaat attattgaca
    28201 aatagcttgg aagtagcaca aaaagttgaa aaaaatatag aaagtatgct aaaagatttg
    28261 ccaacaaagg acatagcata tagttcatgg gaaaataatg gagagataat attggttgat
    28321 gatatggaag aagccattaa aataagtaat ttttatgcac cagaacattt agaagttgca
    28381 gtaaatgagt ataatgatat ttgtgataga ttaactaact atggttcttt atttattgga
    28441 aatctttctg ctgaggtgtt tggtgactat gtttcaggta ccaatcatac attaccaaca
    28501 cttaaagcat caagatatac tggtggtgtt tgggttggaa cttttatcaa aacttgtaca
    28561 aagcagatat ttaatgaaaa agctatacaa tcattagcac ctgtagctga aaagctggca
    28621 aaagaagagg gattatatgc acatgcaaag gctgctgagg ttaggtttaa aaagtagtaa
    28681 aaaattttat tttggcagtc gagacttagt attagactga gataaggaaa acgctgagaa
    28741 cctgaataaa tactatattt tgtgggtctc ggcgcttctt ttatatctgt atataataga
    28801 ataatactat ctgtgtgttt aaatactaac ttaatatttc ttttctaaat aatgtttatg
    28861 aaatagttaa tatttttagt taatacttga aaaaaacttt tgctaactgt gcaaattcat
    28921 ctgcatttgt caatatagca gggtgtcctc cctgactaaa aatgtaaata cttgcttttg
    28981 aaataaaagt tgccatttgc ttgtactctt cttcaagatt atgacgacac atttcgtctt
    29041 ccttacttcc tgtaaataaa attggcattt ctaatttaca caattcttta tgaaacaaag
    29101 ggcgtttctc gtttgcacat tgcaatagag cttttgtatc aagattaaca acattctccc
    29161 aatcttttcc atgacaccat tcatagaatt ttcgtgcttg aatatcttgc tttgattttt
    29221 cccttccagt gattagatta tctatgaagt tatcattaag agtacgtcca tcaaagctat
    29281 ctgctataat tgcttcaact aaatcgggac gttctaatcc agtattaaca gctgcccatg
    29341 ctcctccact tgttccaatt aagccaactt taccacaatt caaatgttca atcagtgcta
    29401 ttgtctgtaa ggcttcatca tgccatatgt caggagaaaa ttgagaaact ctatccgact
    29461 gtccattacc taaaaaatca attaagatac atctaaaatt ttctgcatat aatggcacaa
    29521 gtgctttaaa catattagaa gaaccagtat taccatgcag gaaaattatc ggtttacctt
    29581 gtccatattc tttataaaaa caagaattac cttgatactg aaaatatgac atatattttc
    29641 ctccttttta tttgttaagt taattataac aatataggta tgaatgaaaa acctcatgtt
    29701 ctttcttaga ataaaaatgt gccacgcata aaacgtgaca catttctaat tataaatttt
    29761 gctgtttaag tattctttgt atgcttttct ctgtcaaaaa gtatttctct gataactgct
    29821 tgatactcat tccattttgg aaatttatac agatttgaga attacgagaa gctaagactt
    29881 gtttggtgtt tgtgttttca ccccaatgct ttttgtgctc ttgctttttg ggaatataaa
    29941 tcactttacc atctatatat tcttgcactt gctcaatcag ttctttaggc agtaagtcaa
    30001 tcgaattttg atagctcatt ttgcacctcc taaataatta ttctttagga ttagcaaagg
    30061 ctactgccac tcacaattaa aaataaaatt ttttattatg tacaatagcc tttgctatgc
    30121 acaagttcca attcccataa actaaatact cctttctggt ttgaaaaatt catctgaaca
    30181 ttgatttcgc ttttaagata gagttcaatg acaaatttac atttttatta tatatattca
    30241 gatagataat tgcaactgtc tttgtatgag gatattttat tatagtcaat actataatat
    30301 gtatttatat catcaaacta atatgaacag ttgaaaggaa tatgaacaat aaaacttagt
    30361 caggaagaat aattatgaag cagacaatag agaaatttga ttttaaagtt ttattgaaaa
    30421 tttattgaca aatttaactt gtaaatatta tactaaactt aataaataaa gtttataaag
    30481 taaggtgttg tctatgaaaa atatagttgg aaaaccgcaa acgataaaaa aagtaaatga
    30541 agatttaata aaaaacatta taaaaaatga aggtcctata acaaaaccag aaatttcaag
    30601 cattactgaa ttgagtttag ctacagttaa taagattgta gagcaattag ctttgaaaaa
    30661 tgaagttaaa gtaagtggac taagtgaatc tactggagga agaagagctc aattatttga
    30721 aataaatgca aacttagaac acataatagc tttatattat tatagaaatt gttgtatagg
    30781 ggtagttgcc aatttattag gtgaaataat ttatcaagaa gaatttaata taagaatgga
    30841 tacgtatgaa aacgttaacc aagatacttt ttttgttata gatactctaa taaaaaagga
    30901 aaaaggaaac aatataaggg ctattggaat tggtgtccca ggagttgtaa aaaaaggtgt
    30961 agttaaaaat ataccaacta taaaaagttg ggaaggtata aatttagaaa atttaataaa
    31021 gagtaaatac aatactaaag tgtttataga aaatgataca aatattacta ctattgggat
    31081 ttatcaaaaa cagtataaag acaaatataa aaatatggct cttatgtatt tagaagatgg
    31141 tattggttca ggtatagtta taaatggtga attgtattta ggttctacaa attttgctgg
    31201 agaattaagt tatctaaata tagaatttgg taagtataac tctaacaact taaatcttga
    31261 agattatatt atgagtttaa gaaaaagata tttagaaagt aaagataata aatttaagaa
    31321 agaaatttta tctataatat caaactttat aaggactctt gtatgtgtcc taaatccaca
    31381 agctatgatt atacagtgta gtatattaac caagagtgac atggagttta tagaaaaaga
    31441 tgtaagcaat aatgttggag aagaaaattt tcctaaatta ataaaagtag actcattgag
    31501 agaaggaagt ataaatggag taattagtat gtgtttaaaa gaaactgact atcaatattc
    31561 cttatctaat aaaaaaggag gatattaatg tgaaatattt ggtttcaata gatggagggg
    31621 gaacaaaaac taaattttgt gtaagtgact tagatggaaa catacttaaa gaacatacca
    31681 ctggttcaac taattataag tcagttggaa ttaaaaaaac atatgaaaat attaataatg
    31741 gatttaaaaa aatattaaaa gatttatata tcgattatga cgatattgag tacactgtat
    31801 ttggtatatc tggttgtgat tctcctaatg attataagat tataatggat gaaatattaa
    31861 aaattgggat taacaaagaa aaaatatatc tggcaaatga tgcagtttta gctttttatg
    31921 cacaagctga ttcccctggc ttagtaattg tggctgggac aggttcaatt atactgggaa
    31981 ttaaagaaga tggagaaata tatagagttg gtggatgggg gtataatttt agtgatttgg
    32041 gttctggata tgatataggg agaaaattat taaagaaagt attgctttat tgtgatgaat
    32101 gtcatgagta tagtgattta tttagttgtg tcttggactt ctttggagca aatagttttg
    32161 aacaacttgc atatatgatt actgatataa atgataatgt tgaaatagca aacttagctt
    32221 cattagtgat tgattgtgcc gaacaaggtg ataaattggc tattgaaata ttaagagaat
    32281 catcaactga actatctaaa ttagctcaag taatattgag aaaaatatct aatccaatga
    32341 aaatggataa aagcgaaata aatatagttt tgtctggtgg tacattaaat aaaactgtat
    32401 atgctcaaat gttaatgaat aatttaaaaa cagaaaatac agataaaaat ttaaaattta
    32461 tatctcaaga aaatcagcca gtatatgggg ggataagact tgctatggca ttagctaata
    32521 ggagggtcaa gcatggatag aaaaaaggta atagtacaaa tttttactgg aggttttaag
    32581 gctaaagaaa taaagtttaa tgatataaaa tgtaaactac tagaattatt ggactgtatt
    32641 gatatagaaa aggttatcat gggatggagt gtagatgaag aattatatgt agaaactaaa
    32701 aaactattaa ataaatataa tgttgaacta tatctttggt tgccatgttt ttctgaaata
    32761 ggattacttg aaaaaagtaa tttactaatt gattatatgg ggaaggaagt caagggctat
    32821 gctttacaag aggatgaaaa ttttgagttt tattgcccaa ataataagga aaatataaaa
    32881 aatataaaga aaatatatag tacttatttt agtgatatta aatttgatgg aattttttta
    32941 gataaaataa ggtatggttc tttttcgaat aaactaaatg gtgtttttaa ttgtttttgt
    33001 aaagattgtt taaatatata taaaaaaaat aatattgata aagagtcgtt aatgagagaa
    33061 atgaataatg tgtctaaggg agttatagat aatgaagata ctccatttgg tataacagaa
    33121 tacattaatg gaaaatacaa atttaaaaat aaaatatggg aagatttttt tgaaacaaaa
    33181 aatcaaaata tatacaaggc attattagag ataagtagtt attttaaaag taagggattg
    33241 aaaataggta tagatgcttt ttctcctttt atttcttact ttacaggtca agatttagaa
    33301 aaattacaag aagtagcaga ttttataaaa ccaatgatgt atagaactac aaaagctcca
    33361 gctggtttac catttgaatt tgaaaggttt attgatgaat ccatacataa gaataaagag
    33421 attggaaaaa gaaatttctt agatatttta ggaattaagg agtatgaagg agatgtatat
    33481 cctatagaat ttgtactaga ggaaatcgat tttatgacaa gaaatcttaa taaagatata
    33541 tatgtaggag ttgaaataaa taaaaaggaa attatatctc ctgttacacc taagtacata
    33601 agtgaaaata tttcaaatat aaataagaca acagtaaaag gatatgtttt atcttgggat
    33661 ttgttgtcag caccaaaaga aaatattgat gaaattataa aatggtttcg gaattagtga
    33721 ggtgataaag tgagtaagat attggaaata caacaaatat ataaaagttt tggaaaggta
    33781 gatgttttaa aagggataaa ttttgagtta gaaaagggag aagtaagagc tcttttggga
    33841 gctaatggag caggaaaatc tacacttatt aaaattttag gaggagttca ttctcaaact
    33901 aaaggtaaag taattttgac tggtaatgaa ataatgttta aaaatccaca tcattctaaa
    33961 gaaaatggta ttagtataat ttatcaagaa ttaagcttga taccaacgct tacagtactt
    34021 gaaaatattt ttcttggtag agaaatttta aaaggaagtg tgtttttaaa caagaaagac
    34081 atgcttgagg aatatatgaa aatttgtgag gattttgatt ttaatataga cccacatata
    34141 gtagtttcta atttaagtgt agcaaaccaa caaatggttg agataatgaa agctgtttca
    34201 tgtaattctg aaattatcat aatggatgaa cctacaacat cacttactaa taatgaaaaa
    34261 gatgggctat ttaaaataat aagtagacta aagtctaaag gtaaaacaat agtctatatt
    34321 tctcacatat tagaggaagt ttttaaagta tgtgatagtg caagtataat gaaaaatgga
    34381 attatgattg gaacttatga tgtagaggat ttaactaaat taaagataac tcaacttatg
    34441 acaggaaatg ataatcacaa acttattgag aagaaggatt atacatttgc aaaatatgaa
    34501 gagccaccag tactagaagt aaagaatata agctggtcta acaaaataaa aaatgtttca
    34561 tttaaagttt atagaggcga agttgtaggt cttgcaggtc ttgtaggttc aagaagaact
    34621 gaaattataa atttgatatt tggtatagat aataaagata gtggagatat ttttatcaat
    34681 ggtaaaaaag tagacataac ttctcctaag gttgctataa aaaacaaaat aggattgatt
    34741 cctgaagata gaaaaaatct aggattaatt ttagaacaag ctatatacac aaactcatca
    34801 tcagtacaaa ttgataaatt caagaaattt ttgtttatag atagaaataa agaaattgag
    34861 ttttctaaaa aaggtgttaa ggaattagga ataaaagtta gtgatgtaaa gcaagaagta
    34921 aaagagctta gtggtggaaa tcaacaaaaa gtagtagttt ctaagtggtt agagaaagat
    34981 ttagatttaa taatatatga tgagccgaca aagggaatag atattgctgc aaaagaagat
    35041 attttcaata caatcaaaga attttcaagt aaaggaatag gagtaatatt tatatcttct
    35101 gatttagaag aagtaataag agtaagtgat agaattttag taactagaga aggttctatt
    35161 gtagatgatt taaaaaatga gaatatacag gttcaagata taatgaacag tatatttaat
    35221 gtataaaaaa tgaaaatgga ggactgagat gaagaaagct tttgagaagt taaatttaag
    35281 agattatgga gtattattag gttttttagc tttatgtata gctataagta ttgcaactcc
    35341 atcattttta ggtaaacaaa atatacttaa tcttttacga caatcttcta taattggaat
    35401 aatttcagca ggtatgactt ttgttataat atctggaaac tttgatatat cagttggagc
    35461 agtagcagct cttgcaggtg ctataacaat gaaatttgcg actggtggaa ctaatttgtt
    35521 tgcatccatg ttcttaggtg tagcgatttg tgcagtaata ggattaatca atggtatagt
    35581 agttgcaaag ataaatgtac catcattaat agccactatg gctatggtca ctattgtaag
    35641 aggattgctg ttgatgctta caggaggata tccaattact gaaaatatac caatacttga
    35701 ttacattgga aatggatatt tgtttaatat accaatacca gtagtaattt tctttatagt
    35761 ggtgttagct tcgtttattg tacttaataa aactaagttt ggtagatatg tttattctgt
    35821 aggagggaat caagaagcaa gtaaacttaa tggtataaat gtagattctc acaaagtgaa
    35881 agtgtttatt attaatgctg tacttgcagg aatagctgga atcgtactaa caggaagact
    35941 tgggactgca actgcgattg caggtgaagg atatgatatg gatgcaattg catctgtagt
    36001 aataggaggt acatcagtgg caggaggttc tggttctgta cttaaaactg ttataggagt
    36061 attacttatg agtgttataa acaacagttt taatcttctt ggaatagatg tatatttcca
    36121 gtacatattt aaaggattaa taattttagc agcagttgga tttgattctt atagcaagaa
    36181 aaaacttgct tcaagataaa aaataagggg gattttttta tgaaaaaatt aatgaaacat
    36241 ttagcattgt tgctatcact tgttatgata tttggtttag ttggttgttc aaatggtggt
    36301 gacaaagaaa aaaatggaga aaagaaaata gcagtattac taccaggttc aacaggttac
    36361 tttgtagcaa ctaaacaagg tatagatgca aaatctaaag aattaggtgt aagcgttgaa
    36421 tatgcagatg ctcaatggga tgctagtaaa caattatcac aagctgaaga ttttatggct
    36481 aaaggggtag acatgattgc attatgtgga gttgattctg ctgtaagtga gagaatagtt
    36541 aaagctgcta atgattcaga cgttcctata gtagcattta caaattctat aggaagtaac
    36601 ccaactggag aatttaaagg tttagttaca tatataggac aaaatgagga agaaacagga
    36661 gcattaactg gaaaaattgc taaaaactta ttaggagaaa ctggtgggaa agctgtatta
    36721 atagaaggag taccaggaac tactccacaa gtattaagaa aaaaaggtct tgaaaaagaa
    36781 ttaaaagata gtaatataga aatagtttat aatcaaactt caaattggga gaaagagcaa
    36841 gctttaaaag taacagaaga tttaattcaa aagaaaactg attttaatgt tataatatgt
    36901 caagatgata attctgctac aggtgcaggt caagctttaa aagatgctgg tcttaaggat
    36961 aaagttaaag tcataggttt gggtggaagt aaagatggat taaaagctat aactgatggg
    37021 ttaatagatg gtacaactta tatgtctgct gtagaagaag gtggattagt catagaaaag
    37081 gcatctaaat tccttaaagg tgaaaaaata gaacctgtta cacaaattaa acaagttgaa
    37141 gttaacaaag ataatatttc agagttcaag ggtgaatggt aaattgtcat agataataaa
    37201 taagattttt agagttactt tagaaactat ataaagtaac tcttttttta atttaattta
    37261 gtgataaatt attgaatagt atttctaaac aaataaaaaa ttaatataaa caaagactta
    37321 attatactaa attataagta aaactaatat aaacttatgg aaaaaaggaa aacgtctaaa
    37381 gtattggaat tactatagtg taggtgtagt attaaaaaaa cataaaaaaa cataaaaaaa
    37441 ttgttgaaaa aaatatagaa attttgtata attaaagatt tgaaaagtgc ggtatacaaa
    37501 gccaattctt ttgtatataa tatatataaa ttcagaaaaa ggaagggata tgtatggcca
    37561 ggcggttatt tttagaaagg attggactta tatttttagg ttcagcaata ttagcatttg
    37621 gagtttataa tttttattat ttaaacaaca taacagaagg tggagtgtta ggtattttac
    37681 tactgttaaa aaatttattc aatatacaac cagcaatagc aaatgttgta atagatggtt
    37741 tactactttt agtaggatat aaatttttcg gtaaaaaatt ccttatatat tcaatagtag
    37801 cttctataac tttttcagtg ttatatgact tatttgaagc tataggacct ctagtaccac
    37861 aatcacaaaa tatgctttta tcaactattt tggcaggtgt aactgttgga actggtgtag
    37921 gtatagtagt aaaagcaggt tgtgcatcag gaggagacga tgctttagca ttagtaattt
    37981 ctaagactac atctttgaac atagggcaag tttatttagc aacagatgtt attgtattgt
    38041 tgttatcatt attttatcta tcagcgtttg atatctttta ttctttgatt gctgttacaa
    38101 ttagtggcaa ggtaattgat tttatttatt atcatggtaa aagtttggat atggatataa
    38161 gtaatgatat agttccagaa tgttaatata aattaaataa ctttagattt tattaggggt
    38221 ggcagatttg ccaccttttt tgtgtctaaa tctttataga aagtataatc ccatctaggt
    38281 ttttgcaaat ctcaaatata gaattatgtt ggaatgactg ggaatacgat tgctagatgt
    38341 gcattttaaa aacccaattt tatatttatg aaatactaat cattaatgga tgtttcttaa
    38401 tcctatcttt atacctaaaa tgataagata aatgaagtag caatacaaaa ctaaaatttg
    38461 taaaagagat taaattaaat ggaggagcta aaatgttgga tatagttatg atagcattgt
    38521 tattcatagg atttgtttcc atgaagttac ttgctgattg gtgtgggaaa caaactgaaa
    38581 aaaaataatg taatgtatgg agggattacc tatgtggttt ctggcagttg taattataat
    38641 gttaataata tatttggtat atgcgcttat taatcctgaa aaattttaaa cagtataagg
    38701 ctaataagta agttgaattg gggggaacaa tttttatggt gcagatagta atagtgttag
    38761 cgatttttat gattttagta atacctatgg gcaagtattt atatcatata gctactaatc
    38821 aaaaaacatt tggagataga ctatttgata aagtggacaa ttttatatat aaggtatgta
    38881 gtatagataa gaaaaaagaa atgaactgga aacagtatgc attagcttta ttatttacaa
    38941 atgcagttat ggtatttata ggatatatca tacttagaac tcaaagtatg catattttta
    39001 atccaagtgg aattaaaagt atggaacaag gactatcatt taatacaata ataagtttta
    39061 tgacaaatac aaatcttcaa cattattcag gtgaatcagg actttcatac tttagtcaga
    39121 tgacagtgat aatatatatg atgtttacat cagctgcaac aggatatgcg gctgctatgg
    39181 catttgtaag aggtctagtc ggtaaaaaga aaacattggg aaatttttat gtagatttaa
    39241 ttaggataac aacaagagta cttttaccag gagctttaat tattgggctt atattagtta
    39301 cacaaggagt accacaaact tttgctggga cagaaacagt gactactata gaaggaaagc
    39361 ttcaagatat agctagaggt cctgtggcag ctcttgaatc aataaaacat ttaggaacaa
    39421 atggtggtgg attctttggt tcaaattcat cacacccatt tgaaaatcca acaataatat
    39481 caaatatagt agaaatatta tctatgatga tattaccagg agcttgtgtt gttgcatttg
    39541 gtcacatgat aaagaataaa aaacaaggtt gggttgtgtt tggcgcaatg tcaatcatat
    39601 ttttaatagg tctagtagtg tgctttaaag cagaaagtgc aggaaatcct attttatcac
    39661 aattagggct taatcaaagt atgggaagta tggaaggtaa ggaagttaga tttggtatag
    39721 cacaatcatc attattcaca acagtgacta cttcctttac gacaggtaca gttaataata
    39781 tgcatgatac actgactcct ttaggaggat tagtaccact tttaaatatg atgctaaatg
    39841 tagtatttgg tggtaaaggc gtaggtctga tgaatatgtt gatgtacgct ataatagcag
    39901 tattcttatg tggattaatg gtaggaagaa caccagagtt tttaactaag aaaatcgaag
    39961 gaaaagaaat gaagcttatt gctttactta ttatattaca tccactttta atactaatgt
    40021 tctctggtct ttcagtagca ataccagcag ggcttgaagg aatttcaaat cctggattcc
    40081 atggattatc acaggtattg tatgagtttg catcttcagc agccaataat ggttcaggat
    40141 ttgaaggtct aggagataac actatgtttt ggaatataac aacaggtgta gttatgttct
    40201 ttggaagata tgtgtctatt atagtactac tagcaatatc aagtttgtta gcatctaaaa
    40261 aagctgtaaa tgaaagtata ggaacactta gaacggataa ttttacattt acaatagttt
    40321 tagtacttgt tgttttaatt gttggtgctt taacattttt cccagcctta gcgcttggac
    40381 ctatttcgga gcatctagtg ttgtggcact aaaaaattgg gagggagtaa agttttatgg
    40441 aaactaaaaa aacaaagttt attacaaaag atattttcaa aacttccatt atagaagctt
    40501 ttaaaaaatt aaatcctaaa tacatgatga aaaatccagt tatgtttgtt gtagaaattg
    40561 gatttatagt aacattgata cttacaatag tacctagttt gtttggtgat gaaggcaata
    40621 acttaagagc ttataatggg attgtaacaa taatcttatt tataacagtc ctttttgcaa
    40681 attttgctga agctgtagct gaaggaagag gtaaagctca agcagataca cttaagaaaa
    40741 ctagaaaaga tacagtagca agggttatag atacgttagg aaatgaaaaa atgataagtg
    40801 caagtgagct aaaacttggt gatattgttt tagtaaatgc tggagaagtt attccaaatg
    40861 atggagaagt tatagagggt atagcttctg tggatgagtc agcaataact ggagaatctg
    40921 cacctgtcat gagagaatca ggtggagatt tcgcatctgt tacaggtggt actacagttg
    40981 taagtgactg gttaaagata agaataacaa caaaaccagg agaatcgttc ttagataaaa
    41041 tgatagctct tgtagaaggt gcttcaagac aaaaaacgcc aaatgagatt gctttaaata
    41101 ctttattagt agggttaaca cttatattta tggttgtttt aatatctctt tatccaatgg
    41161 caaactatgc aggtgtaaag attccaattt ctactatgat agctcttttg gtatgtttaa
    41221 taccaactac tataggtgga ttgttgtcag ctattggtat tgcaggtatg gatagagtaa
    41281 ctagatttaa tgtaattgca atgtcaggaa aagcagtaga agcttgtgga gacgttgata
    41341 ctatgatttt ggataagaca ggtacgatta cttatgggaa tagacttgca tcagaattta
    41401 tagcagttgg aaatgcagat tcaaaagatt taataaatta ttctgttatg tgttcattaa
    41461 aagatgatac accagaagga aaatctatag ttgatttagg tatgaaatta ggttcaacag
    41521 gtaagacaaa agaggcagag gaagctgagt ttgtagaatt ttctgcacaa actagaatga
    41581 gtggtattaa cttagctgat ggtagagcta taagaaaagg tgcttatgat agcataataa
    41641 aaagagtaaa agaatctggt ggtacagtgc cagaagattt agaagaaaat gtaaatcgag
    41701 tagctaaact aggaggaaca cctttagtag tgtgtgtaga taatgagata tatggaatta
    41761 tctacttaaa agatacagta aaatcagggc ttgtagaaag atttgctaga cttcgagaga
    41821 taggaataaa gacaataatg tgtacagggg ataatccctt gacagcagct acaattgcaa
    41881 gagaagctgg agtagatgga tttattgcag aatgtaaacc agaagataaa atagatgcaa
    41941 taaaaaaaga acaattagag ggtaaaatag ttgcaatgac aggtgatgga acaaatgatg
    42001 ctcctgcact tgctcaggca gatgtaggtc ttgcaatgaa tagtggtaca acatctgcaa
    42061 aagaagcagc aaatatggta gatttagatt cagacccaac taagatattg gaagttgttg
    42121 aaataggaaa acagctttta ataactcgtg gggctttgac aacatttagt atagcaaatg
    42181 atgttgcaaa atattttgcg attataccag ctatatttac tcttgcaata cctcaaatgg
    42241 agatattaaa tgtaatgaaa ctttctacgt catttagtgc gatattatca gctttaatat
    42301 ttaatgctat aattatccca tgtttaatac ctcttgcaat gaagggagta aaatatagac
    42361 ctatgaaatc acaagctatg ttaatgagaa atatgcttat atttggtctt ggtggagtta
    42421 tagtaccatt tttaggaata aaattaattg atttattgat tacaccttta gtaatggttc
    42481 ttaatttagg ttaataaatg gaggatataa aaatgaaaac attaaagcca gcattacttg
    42541 taagtattgt attgttagtt gtttgtggac ttgtatatcc acttgttttg acaggtgtaa
    42601 gtcaagttgc atttaaagat aaagccaatg gaagtatgat agaagtaaat ggtgtaaaag
    42661 taggttcaga acttattggt caaagcttta cagatgcgag attctttaag ggaagagtat
    42721 catcagtaaa ctataatact tatacaaaag aagatttagt accagataaa gatggaaata
    42781 catcttatgg aggtgtatca tcagggtctt ttaattatgg agctacaaat ccagaacttc
    42841 atgatagagt acaaaaagat atagaaaagt ttttaaagga taatccaact gtcaaaagag
    42901 aggatatacc aacagattta cttacagcat caggttcagg acttgaccct aatataagtc
    42961 cagcctctgc aaaaattcag ataccagcta tagcaaaagc gtctggaata tcagaaagta
    43021 aattacaaaa aattgtagat gataatactt ccaaaaaact ttttggagtt ttaggtgaag
    43081 atagagttaa tgtattaaaa gttaatgtag aggtcgcaaa aatattaggt cttatatagt
    43141 attttgtgga attttagcaa caaaatatta cgcaagattt aatttaaagg ttaaatttta
    43201 aagagtgaaa atcgataatg attttcactt ttttatttga atattactaa tatttggaat
    43261 aaagtgattg taagtataaa atccaaaaaa aggttgcatt atcaaaatga taatactata
    43321 atatatttat cgttatcaat ttgataatag atttggacat ataggaggaa atagtatgtt
    43381 atataataac gcattagagt tgataggaaa cacacctgta gtaaggctga ataatttagg
    43441 ctgtactaat gggtgttcta acatatatgt aaaattagaa aaagtaaatc cagcaggaag
    43501 tataaaagat agagctgttt atgaaatgtt agagggctta gagcaaagag gagaattaaa
    43561 aaagggagat gtactagttg aagcaactag tggaaatact ggtattgcat tatctatgat
    43621 aggaaaatta aaaggatatg aagtagtaat cgtaatgccc gaaacaatga gcgttgagag
    43681 aagagattta atgaaggctt atggagcaaa tttggtgctt acagatggta aagctggaat
    43741 ggcaggttcc atagaaaaag caaatgaact tttaaaagaa aatccaaact ataaaagcct
    43801 aaaacaattt gaaaataaag ataatccaaa tgcacattat aaaacaacag cagttgaaat
    43861 tatgaatgat gtcaaagatt tagatatatt cgtatgtgga gttggaacag gtggtacttt
    43921 aataggaact gcaagatatt taaaagaaca aaatccaaat ataagagtaa ttgcacttga
    43981 accaaaaaaa tctccagcta tatcagaaaa caagactgga cctcataaaa tacaaggaat
    44041 aggtgctaac tttgttcctg aaaattatga ttctagtgta gttgatgaag taatattagt
    44101 agatgatgaa gatgcatttg atacagttaa attacttgca gcaaaagagg gaattttagt
    44161 agggatatct tctggagcaa atatatttgg tgctatagag atggcaaaaa agtatccaga
    44221 taaaaagata gttacagtag ctccagatgg agttgataag tatatgtcta tgggaatatt
    44281 ttaataattt tatttgaggg agtgaatact ttgtttaaga aaataaataa agatattgaa
    44341 tatataatga agaatgatcc agcagctagg tctaagatag aagttttttt actttatcca
    44401 tcagttcatg caatgataat gcataggatg gctcatgctc tttataagaa gaagaagctt
    44461 tttacagcaa gattaatatc ccagatatcc agatttatga ctggcataga aatacatcct
    44521 ggtgctaaaa tgggggaagg tatattgata gaccatggaa tgggtgttgt aattggagag
    44581 acagctgaag tagggaatag ggtgacaata tatcaaggag ctactttagg agctacagga
    44641 aaagatactg gaaagagaca tccaactgtt ggtgatgatg tattaattgg tgctggaaca
    44701 aaaatactag gacctttaaa tataggttca aattcaaaaa ttggtgcaaa ttctgttgtc
    44761 gttaaggatg tacctaatgg tgcaacagtt gttggtatac cagcaaaaat agtaaaaata
    44821 agaaacctag aacctgtaaa aaagaataaa aaagaagtgt cctatgagta tgatgaatta
    44881 gataatgtat attatatata ggatttatat aactataaaa taaactttat aaaaattatt
    44941 ttaaaaggta tttttttcaa atttgaggac ataataaaaa agaactgaat gttacagttt
    45001 tggttcatca atctttgata aacaagattt taaatttgta gcgtctagga ggattttatt
    45061 atgaaagcaa atgttaatca agatacttgt ataggttgtg gattatgtcc atcaatatgt
    45121 ccagaagtat ttgatatgaa ggatgatggg aaatcacatg ttatagttga tgaagtacca
    45181 agtgatgctg aagaatcagc agcagaagct agagaaagct gtccagttga tgcaatagat
    45241 gtgcattaat aaaataaatg cctataaaaa ttgaattttc aatttttata ggcatttgtc
    45301 ttttattcag ttagtatttc aacacctgtt tctgtaacta aaactataca ttcccattga
    45361 gcagataatt taccatcttt tgtataaata gtccaattat tttcttcatc aacaaaaatt
    45421 tcgtgagttc cttcatttac cataggttct attgtgaata tcatcccagg aaccaatagc
    45481 atctcagtcc cttttttaga tacataactt acaaaagggt cttcatgaaa gcttaatcca
    45541 actccatgac cacctatttc tctaacaaca gagtatccat ttttctttgc ataagagttg
    45601 atagcatcac ctatatctcc taaaaatccc catggtttgg caacttcaag acctttttgg
    45661 acacattcct ttgtaacttg aactaatttt tttgcatttt cattaacatt acctatcata
    45721 aacattcttg aagcatctga atagtatcca ttaaaaatag tagaaacatc tacatttata
    45781 atatctccat cttttaagat aatgtcttta cttggaatac catgacaaac ttcattattt
    45841 actgatgtac atacactttt aggaaatcca ttatagtcta gtggagcagg gatagctcca
    45901 ttttgtagtg taaagtcatg aaccaactta tttatatctt ctgtagacat tccaatttcg
    45961 attttatctg aaatataatc caaaattttt gtgtttatta cagcactttt ttttatttcc
    46021 tcaatttgac tttcattttt tataatatca tgagttggta caatatgacc taacttagca
    46081 aatgaatcta ttttattatc catatccata tgacattttt tatatttttt agtacttcca
    46141 caccaacagc tatcatttct atttaacttc ataacttttc atccttcttt tattatttat
    46201 ttaaattatg ggttacataa actattttaa aacataacca ttataaatat tataacataa
    46261 atactaagaa atcctttata gatagtgatt tattcaaagt ataaattatt atatggttat
    46321 tgttgatgaa aagaggatag ttaaatgtat tattggatat tagcgcactt aatagtttag
    46381 ttcaagtttt tcaagaaaat catatgttag aggacaattt tcctttaaag tattttttga
    46441 atcttcatca agataataat gtacaaatga ttctgcaaaa aattcttcta taaacttgct
    46501 tatatatgca tgtgcaactt gcttagggtc ataaagctta tatctttcct gagcaaatac
    46561 ttccataaat tcttcagaat ttgatttttt atttaaaaca tttttatcta tagcatgtgc
    46621 agtttcatgt aattctaaat tttttgatga atgtacattt gcatagctag ggttactata
    46681 acctatttta gccactatag aattatttct atatatacca ggtacatctt tccaagtctt
    46741 gcctgatctt acccaacatg gaggtaattg atattttaaa tcactaaatt ctggttcatc
    46801 agttagattt gaatttatta attttatttt tatatccttt tctttaagtg tctgtaaata
    46861 tttaatattt atttttgcaa gtctgttttt catattttca acttcatctt tatcataatt
    46921 caagtcatca ggaagtataa gcatttgttc aattatatct atactactgt cttttatatt
    46981 ttcagattct tcatcaaact tatattgaag agtattattt tcatagatag ttatatttgt
    47041 attattttct atagaataag agtgaatatc ctctaaatct aaaatattca tttgttgtaa
    47101 aatatgtttt gtttcgccac tccatactac taaagaaagt gaattaaaat taattagtgg
    47161 attttctttt gcttttatat cattgcttat atctacatca aatacatatt caattgagtc
    47221 ttctatgtta agaccatctg tattcttttt aatatataaa tacgcttgtt ttaagtctat
    47281 ataaatctca tctaaagatt cgtcataaaa ttctgataaa ttattagtaa agagttcttc
    47341 acttaaaagt tcatttttat cagttatact ttcaattaaa atattaattt cttttatcat
    47401 atcgtaaata cttatttttc tatttgcttt ttcactagat acattgcatg gcgcaagagc
    47461 aatgcaataa aaatcttttt cttttttata aaaggcttta agtgattttg ataaaagtgt
    47521 aaagtctaca cctatctgta agttgacctt aagtgagtca ttttgtaata attcagtatt
    47581 atttctttta gctgtattta aattgttttc cataatcatt gccccctttt tattagggta
    47641 tcataatttt tttatatgtg tcaatttgtt tttttgaaaa ttataatttt tttgaaaatt
    47701 ttatttttta taatttgtga attttttatt atagaaataa atatgttatt attatgtcaa
    47761 aatttagcat tagattcatg tagagtatgt tttatacata tattataatt aattctttga
    47821 agattgcata ttcaaaatac acaccatttt ttttaattct ataatataat atttatatat
    47881 ttaatgttag gatgtgattt aaggtgtatt ttacatatat tataagatgt aaagatgatt
    47941 ctctatacac tggatatacc agtaatatag ttagaagaat gaatgaacat aaattaggaa
    48001 ttaattcaaa atacacaaga gcaaagggat ttgaaaaact agaagtttat tttgtgacca
    48061 acacaaaaag caatgctatg aagttagaat actatataaa aaaattaact agaaataaaa
    48121 aattgtctat aataaaaaac ccaagtatac ttataaattt aattgataat aaagaagatt
    48181 atattattgg taaggaaata gaacaattaa cataaatatt tatagtaaca ttataatggg
    48241 tgcatatggt gtaaaaactt gacaataaat actattgtaa tataatgaag ttataaatat
    48301 agtaaattaa aatagctagg ggagccaaga gctgagaggt ataccgaccc ttacacctga
    48361 tctggataat accagcgtag gaaagcttag taaaaattca agtatgtatt atttgtgata
    48421 tatgctattt ctaagctata cctattgtag gtatagcttt tttaattaag ttatttaaat
    48481 taaactttag gaggcaacaa tgagtaatta taaaatacca acacttacaa tagccggctc
    48541 tgattcatct ggaggagctg ggattcaggc tgatttgaaa acgtttagtg caattggtac
    48601 ttatggtatg agtgtaataa cagctataac agcacagaat actaaaggag tttttgctgt
    48661 agaggattta aataagaaaa taataaaaaa acaaatagag gcagtctttg aagatatacc
    48721 tccaagagct gtaaaaatag gaatggtttc aagtcctgag attatacttg aaatagttga
    48781 gaatctaaag aaatacaatc caaaatattt ggttgtggac ccagtaatga tatctaaaag
    48841 tggatattat ctattaaagc cagaggcaaa agaaaactta attaagtatt tgataccact
    48901 tgcatacata attacaccaa atataccaga ggcagaagaa ataacaggaa taaaaataca
    48961 taatgtagat gatatgaaga gagtaggaga agaaatacta caacttggac ctaaatttgt
    49021 acttatgaaa ggaggtcatt tagatggaga agcagtggat attttagttg gtaaaaatat
    49081 atttaaagtt tataaaagtg aaagaattga taaaaaaaat acacatggaa cagggtgcac
    49141 attatcttct gcaataacat cttatctagc attaggatat gaaataacag aagcagtaaa
    49201 tctaagtaaa atctatataa cagaagcaat aaaaagaagt tttgatatag gtcatggagt
    49261 aggaccagta catcattttt ataaatttga gtaataaaaa aatattggag gtagaatatg
    49321 tataatttaa ttaaagatgt aaaaaaatta aatccattgg taattcatta tactaataat
    49381 gtaactataa atgattgtgc taatgtaact ttagctgtag gagcaagtcc tcttatgagt
    49441 ttttcatatg aggaagtaga agaaatggta agtgtagcaa actctgtagt aataaatata
    49501 ggaactatga actcaaatat gttggattta ttcctattag ctggaaaagc agcaaataag
    49561 tacaataaac ctgttgtttt ggacccagtt ggagtatttg caagcaaagc gagagcagaa
    49621 cttacaagta gacttttaaa tgaagtcaaa tttagtgttg ttaaagggaa tgtatcagaa
    49681 ataaagttta taggtggctt taatgtaagg ggtaaaggtg tagattcatt tgatgaagaa
    49741 gaagattcta ctgagataat aagaaagatt gctgaaaagc ttgaatgtgt agttgtagca
    49801 actggaaaaa tagatataat aactaatggt aaaggtacat ataaaataaa caatggaact
    49861 gataaattaa aaggaattac aggaactgga tgtatgactg ctagcttgat tgcaagtttt
    49921 atggctgtta ctgagaatat attagaagca gcaacaatgg gtgttcttac aatgtcttta
    49981 agtggggaat tagctaattt aaataatcca ccaataggta catttaaaga aaatcttatg
    50041 aatgctattt atcaaatgga tatagatgct ttaagtaaaa attctaatat tgaattttta
    50101 aattaataaa gagtaaggga gacttaaaat gattgataaa gaatctttaa aaaaatgttt
    50161 aaagttgtat ttagtaactg actctgaaat gcttaaaggt agagactttt ataaatgtct
    50221 tgaagatgca atatcttctg gaataacaac tgtacaactt agagaaaaaa atgcttctgg
    50281 aagagagttt ttaagaaaag ctatgaaact tagagaaata actaaaagat atggtgttaa
    50341 gtttataata aatgatagag tggatatagc acttatttgt gatgcagatg gagtacatgt
    50401 aggacagagt gacattgatg ttagagaggt tagaaagctt ataggaaaca ataaaattct
    50461 aggagtatca gcaagaactt tagaagaagc tatttgtgca aaaaatgatg gcgcagacta
    50521 tttaggtgta gggtctatat tcacaacatc tactaaatta gatgcaaaat cagcttcgtt
    50581 tgaaactgtt aaagaaatta aagaaaaagt agacatgcca tttgtactaa ttggaggtat
    50641 aaatttagac aatatagata aacttaaatg tttagaaagt gacgggtatg ctataatatc
    50701 agctatatta aaagctgaag atatctctaa agaagtggaa aagtggacat taaaaatata
    50761 aaattggctc tggtagtgaa aaaaatggaa aaatttgata taatctaaga gtaaaattta
    50821 agcaattata aatgataaac ttttctacat atacttttta atcaagatat atgtagattt
    50881 ggttaaaaag gagctataaa tgattaggat attgttagtg tgtgttggag gcatgtcttc
    50941 taccctattg gtaaataaaa tggagaagga tgcaaaaaaa agaaatatag actgtaaaat
    51001 atgggcagtt ggagaaggag atataaaatc ggagcttgat aactttgata ttttacttct
    51061 tggaccacaa cttagattta tgcttgatga cgtaaagtct atagttggag atagagctcc
    51121 agtatctata atagatatgg taaactatgg cacttgtaat ggtcatgctg tgttaaattc
    51181 ggttttagaa atattaaaat aaataataaa agtggattct atataataga gtccattttt
    51241 attatttgtt attaataggc ttaaaactta gcttaccatt tcttttttta atctccacat
    51301 agcaagtgaa aaacttgaac agcacaatat taaaaatagt aggataacag gcattatatc
    51361 tccaataaga atagtctcac caaatattaa gctacgtaaa gcgttaataa catgggtaaa
    51421 tggattgagc atcactgcta cttttaatcc tccagataaa ctttctatag ggaaaagagc
    51481 tgaacttaaa aagaaaatag gaagtacaat tgcagtcata attgtttcat aaactatttc
    51541 atttggcaat aataaactta tagaataagc tagacttgat aaaaagaagg ctgtcataaa
    51601 tatcagtact atcataagta ggattccacc aatgccagat tctatcctta ctgagaagaa
    51661 tatacttact atacacaaaa tagttacttc tatgaaagaa actaagatag cttctaataa
    51721 ttgaccaagg acgattgaat acctgctgat aggtgcaatt aagactctat agaaacttcc
    51781 actgttcttc attataaagt ttataatacc accactacta caagaagaaa acacaaccag
    51841 tacaatgata cctggtagta taaaagcagt ataattattg atatttatat tattcatagt
    51901 ttggtttgca atagaactat aaagcacaag ccaaagaaaa ggttgtaata tagtaactac
    51961 aaatgagatt ggatttttaa aacgccactt catactacgc cataagatat ttaacattcc
    52021 cattcctcct ttaagctttt tttagaactt gtaagtgcta aaaatacatc ttcgagactt
    52081 ggctctacaa tttctattgc atcaaattct atatcatgtt ctaaaagcca tttatttatt
    52141 aaagtaaaag cagttctact atcgtttaca cttataaaaa ttgaattttc tcgtacgctc
    52201 ataaacttta ctaaaccagt acttttaatt gaatctttat atttttttat atcttcagta
    52261 ttatgaaaag ttatacgtag tatattttgt ctaatgtaac tacgtaaact tgatggtgtt
    52321 ccttgtgcta aatcctttcc attcttcata atacaaatat tatcactcaa ttgttcagct
    52381 tcttcaagat aatgagtagt tagaaatata gttgtgccat actcatctct aatttttaat
    52441 aacatatccc acatagattt tcttgaatcg acatccatac caacagttgg ttcatctaaa
    52501 aataggattt taggagatga taccatattc atagctatgt ccaatctacg ttttacaccc
    52561 cctgaatatg atgaagtagg atattttaag taactagata agtcaaactt atcaattaaa
    52621 gagtctattc tttgttttgc aatctgtggt tctactttat acattttact ttgaaatacc
    52681 atattttcca taagggataa atgttcatca atagagattt gctgtgctac acaagcaatt
    52741 tgagtacgta tccaagaagg attatctact aaatcttttc caaacattgt tacatttcca
    52801 gatgtaggtt tgtaaaaggt agtcaaaata tttataagag aagatttacc agcaccatta
    52861 ggaccaagta aagaaaaaat ttctccagca tttacattaa agcttagacc atttaaagct
    52921 ttcacaccat ttttatattc ttttactaaa ttgtctattt caatcgctaa catatattat
    52981 tcctcctctt taagtggaaa tattatctct gtaatatagt tatctgggtt tccttttatc
    53041 aacatacctg gtcctttaat aaatacttct ctccaaggag tttgtatttt tatattattt
    53101 tcatgaatat atttaaatat catttcatac gtttttggca aattactata agagcctgtg
    53161 tgagtaaaaa ataaagcttt tgttttagga aattcttttg tagttatacc catacgattt
    53221 ggagtttcag cagttggaac acataattcc atttctgcaa caccagtttt ttggtcaaca
    53281 tcatagtagc aaaagaatgg tgcaccgtta gactttcctt ttatagcttt aaatacattt
    53341 ggaaaatact ttgttgcctc agtcataggt ccattataac gcatggtagc cactgtgact
    53401 gattcgatat ttttgatttc aattttgcaa ttcatttgtt tacctcctaa tgtgtgttca
    53461 tattcttact agatttttaa gcattaatac atataagatt ttgattagtt gaaaacatat
    53521 aatcttatct cgtttgcttg ttttcaagtc taacataaca taaaatatat atcctctcat
    53581 ttgatgctcc attttgtaaa gttattattt aagctttact ttagattttt tagcaaatta
    53641 aaataaagca atttataaaa taagtattta caaattaagt gtattaatcg tataatacac
    53701 ttaataggat actagataaa gtctgaaata aaggcgtatt tttttaaagt aagtgtacta
    53761 tcgtattaat acactagaat aggaggaatc atgaattttg aattagataa tacaactccc
    53821 atttatttgc aaatagtaaa gtatataaag agacaaatag taacaggaga gttgaaacca
    53881 ggagagacaa taccatcaag aagagaaatg gcacttaatc taaaagtaaa cttaaataca
    53941 gttcaaagag catataagga gatgggtgat atgaatataa taaatacttt taaaaattat
    54001 caaagcagtg taacagttga tgaaaatata ttaaaaaatt taaaattaga gcttataaat
    54061 gaatcactat ctgtttttat agaagatatg aaagcaataa atgttagcaa agaagaagtt
    54121 ttaaaaataa tagaagataa gtattagttt tttaacaaat agaaaactta gtttagaaag
    54181 tttatttata agcatattgg atgtggagga tagtaaatat gatagaaata aagaatgtca
    54241 gcaaaacata taaaaggatg caagggctta aaataagaaa gatagaagct ttaaaaaatg
    54301 taagttttaa tatagaaaag ggaaaaataa ctgcattact tggtataaat ggtgttggta
    54361 aatcaactat gttaaaagca atagcaggac ttataaacat tgatagtgga gaaattcgta
    54421 tagatggaga aaaaataaat gaaaaggtat acaataaatt ggcttttgtt ccagatgtac
    54481 aatctcactt tagcaataca acaataaaag aaacatttga atttatggaa attttttatt
    54541 caaagtggaa taaagaaaaa tcaaaagaaa tgatggacat atttaaattg gatgaagatg
    54601 aaataattga taacttgtca aaaggaaaca ttgcaagagt aaaattaata cttggatttt
    54661 gccaagaccc agagtacata cttcttgatg aaccatttac aggaattgat ttgtttaaga
    54721 gggaagagtt tataggagta atagcgcaat atatggagga aaatcaagcc attattataa
    54781 ctactcatga gatagtagag atagaaagtt tagttgatga ggttgtaatt cttgatgaag
    54841 ggcagattat aacttcattt aatgcagaag aattaagaga aagagaaggt aaatctatat
    54901 tagataagat gagggaggta tataagaatg aataaacttc tatatctaat aaatgtagat
    54961 ttgagaagaa gcaataagtt ttatatagct tatatatcat ttttttcatt aattacactt
    55021 agtttaaatt tattcgaaat taataaattt aaaaattcta aatttattat gaacttagca
    55081 atagaagatt ttggaggtat attttatgga ctagggatac ttagtaatct tggttttatc
    55141 caaagtatat tgttctttgg gatattggga ctttttatat actatatttt tatgtggaaa
    55201 agagagttct tttcaaataa tcaaagtatt tatacactta tgatgttacc tcaaaataag
    55261 tttaagattt gtatatctaa atcaatagcc ttgataacaa tgatatatgg ttttttgata
    55321 agtcagacag caacattatt tatatgtaaa tatatattta atttcatttt tagaaatatg
    55381 cctataatca atatgaactt tgccaaagat ttatattatt taaacttgaa gagtatacca
    55441 attgatttta tctcttttat ggctatttat gtatttttac tacttatagc tatttctatt
    55501 gtaaattgct gtatattatt tatcttttcc tatataaata aattttatgt aattttaatc
    55561 actttgctga ttatagcagg cttatatttt tcaacaatat atataaatat aatcacttta
    55621 tttagaaaat attataatct tataggattt caatttaaca atttagtagc agggttatta
    55681 agttttttaa ttataatgtt tattctaaat ggaatatctt atttgctaat taaaaagaaa
    55741 gtatctcttt aaggaggggt ggtatgaaat taaaatctaa aatatctata tttattatat
    55801 ttttgacttt agcaatatat tttagtatag gtttattaaa taatgaagat aatttaaaga
    55861 taaaaactat aaaaggtgac tctaatgaat tagaccatat aaacataaat tttggatatg
    55921 ctttgaatgg atatataaat tcatattata caataaatgg aagcaacaaa accaaaaaga
    55981 ctgaattaat aaaactacaa aaggatagta agaacacaaa taatttaatt gatgtatcta
    56041 gtggttcaga tttaattgct catgttggat ttgaaatgaa tgaggagtca aaagatataa
    56101 actttgtgat agatgagaaa aaagaagatt tagaaaaagg tgtatttcca tcagaaggta
    56161 gtgataaaga aattgaatat gaaaaattag atatgaataa ttttacaagg acaagatata
    56221 aagtagataa aagtacagat gattattatg caaagatact agcatcaaaa agatataaaa
    56281 aatacttata tgtatctgta ctttatgcta caagtgattc atcagaaaat aacaaagaat
    56341 attcaagtac tatagatata ataaaaatta atccagaaaa taaaaaaatc aagactataa
    56401 aaagtataaa tttaagtaat tatttttccg aaaaatacca aaacatagag aacataggtg
    56461 taagttatgc tagcaaatat gaggataaga tgtatatttt agtaaatgta ctaaatacaa
    56521 acataggtga taatagtaat tctaaatttc atttacttga gtataatctt gaagaaaata
    56581 aggaaagcat aatggaatta aaaactgata gcaaaatggc tttagcaaaa gcaaagttag
    56641 aagctaataa attatatatg gtaatgtcga atgattatga taatagttca attacagagt
    56701 taaatttact tacctataat atattagata aaagcttaga tgaagataaa tatgttttag
    56761 ataatagaga aaaaagagga attagaagta ttgaaattga ttcaaataaa atcgttgcat
    56821 atacatcaag gctaaactct atattatctt gggatgataa atttatgcta tatataataa
    56881 ataaaaattc taaggaaatt gtatatgaag gagaattaca atttaacagt tcaaatagta
    56941 tgttagaatt tgaaataaag taggtgagtt gatgaaagat ttaataagat tattcgaatt
    57001 tgaattaaaa agaaatataa agaattatat atttataata atttgttgtt gttcttttgt
    57061 aattttaaac atagtaaaaa atttaaatga ctataattac ataatagaaa atgcagttaa
    57121 aagtgaacag ttaacaaaaa tcggaaatac gatagaaacg gtaaatgtta caggtttctc
    57181 aagctttaga aatataatgg gttctacaga atcgtggttt atgtttggta taattgcatg
    57241 tatttgctat gcttttttta tttggtatag agactttaat ggtagaagta aatctatata
    57301 tacacttata atgctaccta aaaatagaat caatatttat atatctaaat tattaaatat
    57361 attatttcta gtgtatagct atacagtagt acttacaata tctttgttta ttgcaagtaa
    57421 gttgttgcct agacatatgc ttggtaatgt cacaaactat ggttttgtac aagaaacaat
    57481 atatgagtta aaaatgttac ttccatatag ctttgaaata ctatttgtag agtatatatt
    57541 tttattgata ggatttgtat ctgtagtatt tacatcaatt cttataaata aatctattta
    57601 taaagtaagc actttaataa gttttctatt tttagttata gaaattttag tgtttataat
    57661 ttctatagaa tttattatac cttacgaata cagtgatgta tttactgttc tatattcaag
    57721 tataaacata tttgtatgta gtcttatatc taataaactt ttgaagcaaa agattgactt
    57781 ttaggaggga tattatgaaa gcaaaaaata taggaaaata tacaatatgt tttataatag
    57841 tatgtttttt aatgattact atgaccttaa tattgagtta ttttaataag gataaactat
    57901 ctgtaaaaac tttaaaaggc aatgtaaaag atatagggag agtaagtgta gtatatacac
    57961 ctaatataag caaattttct tatgaggagg taattataag taaaaatgga gtaagaaata
    58021 atacaaaccc aaaatcaaga attagaaatg attatttaaa tattgacaaa aaatacagtg
    58081 actttgttaa tgataaagga aaagaattta tatataaaga tgatttgaat ataggagaag
    58141 cgtatacctc tgttaagtct gatttagtac aaggaatgaa tgctttaaat gattgtataa
    58201 aggtttcaaa taaaaattta aaaagtgggg tagaagaaaa ttttgatatt aatttaaata
    58261 agtctgattt taaagaaaat agttggaaaa ccttatttaa caaaatatat aaaggtaatt
    58321 tatatatggt aattagtgaa actaatattt caggttctaa agtcaataat atttgtatat
    58381 taaagataga tataaaaaat aagtcttata aattattaaa tagatttaat ttaggattac
    58441 agaatggaga acaacaaaat atcaatgaaa ttaaattttc tattggaagt aaattatact
    58501 tagaaatagt aaataataaa agtaaaaatg gatatattga aggacatgat agttactcta
    58561 actttattat atatgatata gaagataaca cttttaatat aagtaataaa tttatggata
    58621 atctaaacaa agaaaagaat gcaaatccaa aggagattgg cttattaagt aaaactaagc
    58681 tagattatat ggtaaaaaac aataaattga atcttatagt tacggatatg agtaattcca
    58741 taactaatct tgtttatgat attaattcta atgagattaa attagaagat tatgagatac
    58801 ttgatttaaa agtagattat aatgaagcat catctggagt taggaaagtt aagctactgg
    58861 atgataagat atattctatt tcaggtatta agaacagtat atcaggagaa ttaaaaggat
    58921 ttaaagggat tattgatgta gtcggaacta agccagtaaa atttcaagta tttgatatga
    58981 aacttaaaaa gaatatttat gaagctgagc taataaatgg agatataagt ttacaagaaa
    59041 agttattttt tgttgcaaat taagtgttag aattaatttt agaactttaa acttttatat
    59101 gtatcacaga taagtataag taagggagtg tctcaaaata aactttttag ctcatgagac
    59161 acttttttta tatgaaatca aatatatttt cattgtttag atttattttg ataatgaaaa
    59221 aaagattat
//
LOCUS       DAMJWC010000017        58553 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMJWC010000017 DAMJWC010000000
VERSION     DAMJWC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.017"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            105..455
                     /locus_tag="PC503_001253"
     CDS             105..455
                     /locus_tag="PC503_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2527262.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            474..2117
                     /locus_tag="PC503_001254"
     CDS             474..2117
                     /locus_tag="PC503_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF2527263.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2198..4255
                     /gene="recG"
                     /locus_tag="PC503_001255"
     CDS             2198..4255
                     /gene="recG"
                     /locus_tag="PC503_001255"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF2527264.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4314..4868
                     /gene="rsmD"
                     /locus_tag="PC503_001256"
     CDS             4314..4868
                     /gene="rsmD"
                     /locus_tag="PC503_001256"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF2527265.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4870..5367
                     /gene="coaD"
                     /locus_tag="PC503_001257"
     CDS             4870..5367
                     /gene="coaD"
                     /locus_tag="PC503_001257"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF2527266.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5371..5895
                     /locus_tag="PC503_001258"
     CDS             5371..5895
                     /locus_tag="PC503_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527267.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6239..8158
                     /locus_tag="PC503_001259"
     CDS             6239..8158
                     /locus_tag="PC503_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2527268.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENIL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8171..8458
                     /locus_tag="PC503_001260"
     CDS             8171..8458
                     /locus_tag="PC503_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527269.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8591..9850
                     /locus_tag="PC503_001261"
     CDS             8591..9850
                     /locus_tag="PC503_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF2527270.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLMGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9853..10593
                     /locus_tag="PC503_001262"
     CDS             9853..10593
                     /locus_tag="PC503_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2527271.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10916..12226
                     /locus_tag="PC503_001263"
     CDS             10916..12226
                     /locus_tag="PC503_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2527272.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLISS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12324..13241
                     /locus_tag="PC503_001264"
     CDS             12324..13241
                     /locus_tag="PC503_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2527273.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            13257..14066
                     /locus_tag="PC503_001265"
     CDS             13257..14066
                     /locus_tag="PC503_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2527274.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14124..15872
                     /locus_tag="PC503_001266"
     CDS             14124..15872
                     /locus_tag="PC503_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF2527275.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKVREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     RYDKVKKYVLELLDRV"
     gene            16134..17156
                     /locus_tag="PC503_001267"
     CDS             16134..17156
                     /locus_tag="PC503_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF2527276.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEVSRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17161..19467
                     /locus_tag="PC503_001268"
     CDS             17161..19467
                     /locus_tag="PC503_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2527277.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTTS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            19439..20554
                     /locus_tag="PC503_001269"
     CDS             19439..20554
                     /locus_tag="PC503_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527278.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLNSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20572..21990
                     /locus_tag="PC503_001270"
     CDS             20572..21990
                     /locus_tag="PC503_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2527279.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22005..23213
                     /locus_tag="PC503_001271"
     CDS             22005..23213
                     /locus_tag="PC503_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527280.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(23287..24675)
                     /locus_tag="PC503_001272"
     CDS             complement(23287..24675)
                     /locus_tag="PC503_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2527281.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IGFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            25016..26350
                     /locus_tag="PC503_001273"
     CDS             25016..26350
                     /locus_tag="PC503_001273"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF2527282.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREISYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26492..27409)
                     /locus_tag="PC503_001274"
     CDS             complement(26492..27409)
                     /locus_tag="PC503_001274"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF2527283.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27617..28501
                     /locus_tag="PC503_001275"
     CDS             27617..28501
                     /locus_tag="PC503_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF2527284.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28714..30555
                     /locus_tag="PC503_001276"
     CDS             28714..30555
                     /locus_tag="PC503_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDF2527285.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSVVSKKVDKIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30860..31567
                     /locus_tag="PC503_001277"
     CDS             30860..31567
                     /locus_tag="PC503_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527286.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31561..32871
                     /locus_tag="PC503_001278"
     CDS             31561..32871
                     /locus_tag="PC503_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527287.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNVAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            32988..33671
                     /locus_tag="PC503_001279"
     CDS             32988..33671
                     /locus_tag="PC503_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527288.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDEPFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33664..36051
                     /locus_tag="PC503_001280"
     CDS             33664..36051
                     /locus_tag="PC503_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2527289.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGKMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKLNDKSNLSI
                     EQAKSKLNKIANDVGLDTINVAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQVKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36331..37473
                     /locus_tag="PC503_001281"
     CDS             36331..37473
                     /locus_tag="PC503_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2527290.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            37492..38016
                     /locus_tag="PC503_001282"
     CDS             37492..38016
                     /locus_tag="PC503_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2527291.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38116..38934
                     /locus_tag="PC503_001283"
     CDS             38116..38934
                     /locus_tag="PC503_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2527292.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYIASNIHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            39012..39323
                     /locus_tag="PC503_001284"
     CDS             39012..39323
                     /locus_tag="PC503_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF2527293.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSVSSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39500..40183)
                     /locus_tag="PC503_001285"
     CDS             complement(39500..40183)
                     /locus_tag="PC503_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527294.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(40276..40917)
                     /locus_tag="PC503_001286"
     CDS             complement(40276..40917)
                     /locus_tag="PC503_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2527295.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHTYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(41091..43094)
                     /locus_tag="PC503_001287"
     CDS             complement(41091..43094)
                     /locus_tag="PC503_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2527296.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELMKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(43247..43885)
                     /gene="recX"
                     /locus_tag="PC503_001288"
     CDS             complement(43247..43885)
                     /gene="recX"
                     /locus_tag="PC503_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF2527297.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            44161..44850
                     /locus_tag="PC503_001289"
     CDS             44161..44850
                     /locus_tag="PC503_001289"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF2527298.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            44851..45423
                     /gene="yqeK"
                     /locus_tag="PC503_001290"
     CDS             44851..45423
                     /gene="yqeK"
                     /locus_tag="PC503_001290"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF2527299.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            45540..45890
                     /gene="rsfS"
                     /locus_tag="PC503_001291"
     CDS             45540..45890
                     /gene="rsfS"
                     /locus_tag="PC503_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF2527300.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            46244..48664
                     /locus_tag="PC503_001292"
     CDS             46244..48664
                     /locus_tag="PC503_001292"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF2527301.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDILDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            49517..50185
                     /locus_tag="PC503_001293"
     CDS             49517..50185
                     /locus_tag="PC503_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2527302.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            50225..50305
                     /locus_tag="PC503_001294"
                     /pseudo
     CDS             50225..50305
                     /locus_tag="PC503_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(50668..51785)
                     /locus_tag="PC503_001295"
                     /pseudo
     CDS             complement(50668..51785)
                     /locus_tag="PC503_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861579.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            52001..53371
                     /locus_tag="PC503_001296"
     CDS             52001..53371
                     /locus_tag="PC503_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HDF2527303.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            53665..53823
                     /locus_tag="PC503_001297"
     CDS             53665..53823
                     /locus_tag="PC503_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527304.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   54109..54667
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=54109..54138
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaatt"
     regulatory      complement(54808..54905)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            55132..55515
                     /locus_tag="PC503_001298"
                     /pseudo
     CDS             55132..55515
                     /locus_tag="PC503_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(55693..56688)
                     /locus_tag="PC503_001299"
     CDS             complement(55693..56688)
                     /locus_tag="PC503_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF2527305.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(56809..58437)
                     /gene="aspD"
                     /locus_tag="PC503_001300"
     CDS             complement(56809..58437)
                     /gene="aspD"
                     /locus_tag="PC503_001300"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF2527306.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        22560 a         6647 c         9934 g        19412 t
ORIGIN      
        1 tttatagtat gatatgatta taattttata taataaataa gtaaaaatag taaaaaataa
       61 attaagaaat gtttttaata aaaataagct taagggggtc aaccatgagt gcaaaggtaa
      121 cgaatcaata tggaaatata gaaatagata atcaagtaat agctcaagtc gtatatagag
      181 ctgcaatgga aagttatggc ttagtaggtt tagcatataa gtctaaagga atagtagagc
      241 tattaaaagg cgagaacgca actaaaggtg taagagttga ggaagtagaa gaagatgcca
      301 tagcaatcga actttatgtt ataatacaat atggtacaaa tatatctact gttgccaata
      361 atataataga tagagtaaaa tatgtagttg aaaaaatgac tggcgtaaga gttactagaa
      421 ttgatattaa tgtacaagga ataagagtta agtaatttca taggaggaaa caaatgattc
      481 aatatataga tggtaaaagg ttaagggaga tgtttatttc aggtgcaaac aatctccaaa
      541 acaataaaga gttagttgac aagttaaatg tattccctgt accagatgga gatacaggaa
      601 ctaatatgtc attaacaata tcttatgcct taaaagaatt agcaaaagtt gaaaatgata
      661 atatatcaga tatcggaaaa gcattatcta aaggttcttt aatgggagct agaggaaact
      721 caggagttat actttcacaa ataatcagag gtatagctaa atctatagaa ggaaaaagta
      781 aattatcaac agaagattta gcaaaagctt ttaaaaatgg ttcagacaca gcatataaag
      841 ctgtaataaa accaattgaa ggaactatac ttactgtagt tagagaaagt ggagagtttg
      901 caataaaaac tgcgaaaaaa gagaaagatg tagtaaagtt tttaagtatg cttgtgaagg
      961 aatcaaattc ttcattagaa agaactccag accttctaaa gaatctaaaa gaagctggtg
     1021 tggttgactc tggtggaaag ggtcttgtac ttatatatga aggaatgtta gcttctataa
     1081 aaggcgataa catagaaata aaaaatgttg acctagatac taatatttca acaagtatgg
     1141 attttgcaaa gagtactact agcacagatg atataaaata ttgctattgt acagaattta
     1201 ttttagaaag ttctaaggta gaagatacta aaataagaga cataatgatg gcttatggtg
     1261 atagcctagc agtagttgga gatgatggag tcataaaggt acatgtacac actaatgacc
     1321 caggaaatgt acttcaagaa gctctaaagt acggtcaatt attaactata aaaatagaaa
     1381 atatgaagtt acaacatgaa aatacattac tggatgtaga agaaaagaaa gaaaatgata
     1441 gtgaaccttt agaagaagaa aaagagtttg ggtttatagc tacttctatg ggtgaaggtt
     1501 tggcaaatat atttaaagat ttcggagttg accatataat agaaggtggt caaactatga
     1561 atccaagtac tgaagatttt atgaatgcta taaagcatat aaatgctaaa aatatattta
     1621 ttttcccaaa taacagcaat ataataatgg ctgctaatca ggcaaaagaa ttgagtgata
     1681 aaaatataat agttatacct acaaaaaata cgcctcaagg atttgctgca ttagtaactt
     1741 ttaatggaga attaagcgaa gatgaaaata aagaagctat gatgaatgct ttaaactcag
     1801 ttaaatcagg tcaagtaact tttgctgtta gggatacagt gatgaatgaa attgatgtta
     1861 aagaaggtaa tataattgga attgcagaag gaaatttatt atcagcagga gattatgtgg
     1921 atgaagtaac atcaaacctt attgaaaagt tggttgatga agatactgct ataataacat
     1981 tattctttgg tgaagatgtt acagaatctc aagcaaatga actacgtact tctttagaag
     2041 aaaagtttga agatgtagat gtagagttat attatggagg acaacctctt tattattact
     2101 taatttcagt tgaataatga ttataagaac ctgtatgacc aagtagcttt tataaaattg
     2161 gttgtacagg atttttgtgt agtaggtgat atatttgttg gatttatata aagatgttca
     2221 atatgttaag ggaataggac ctaaaaaagc agataaatta aataaactgg gtatatttac
     2281 actaaaagac ctattgtatt attttccaag acaatttgaa gatagaaata atctaaagaa
     2341 aatagcacaa ttagaagatg gtgagaaagt tacgataaaa gcagtaatat caagtataaa
     2401 tacatttagc ccaaaagaag gtatgacttt aacaaagatt gatgtaaaag atgagacagg
     2461 ctcggctaaa ttagtgtttt ttaataagag ttatataaaa aatacttttc gtccaggaga
     2521 ttcaatatta gtttttggga aggttaagaa aaaatttaat aacttagaac ttacatcatg
     2581 tgaattagaa tatcttacta attcacctaa gaatacatgt agatttatgc ctgtgtacca
     2641 gcttacatac ggtgttacaa ataaagaaat tatgagtata attagaacag tacttgaaga
     2701 taaagaatta attatacaag aatatatgcc acaaagaatt atagaaaaat ataggctatg
     2761 tagtatagat tttgcagtta gaaacataca ttcaccaagt agtaaggaat cattaaaaat
     2821 agctttatat agaattgtat ttgaagaatt acttatacta caactagggt tgtttgtatt
     2881 taaaagtggc agaaataaag aagatggaat aaagtttgaa acaagtaaag acttaaaaaa
     2941 aataataagt gctttaccat ttaaactgac taaagctcaa aacagggcat tagatgaaat
     3001 tatacaagat atgaatttag agaaaataat gaatagattg gtacaaggtg atgtagggag
     3061 tggtaaaaca gtagtagctc tcttagcact tgcaaattgt gttttaaatg gttatcaggg
     3121 cgctttgatg gcacctacag agatattagc agggcaacat tatatttcac ttactgagtc
     3181 tctaaaagat tttggaataa atgtaggtct attaataggt agtcttacaa aaaaacaaaa
     3241 ggatacagta ttggaacaaa taaagaataa tgagattgat atattaatag gtacacatgc
     3301 actaattgaa gataaggttg aatttaataa tattggttta gttataacag atgaacaaca
     3361 tagatttggt gttatgcaaa ggagcaaact ttcattgaaa ggagcaaatc ctgatatatt
     3421 agtaatgaca gcaacaccaa taccaagaac tttagcactt atactctatg gagatttaga
     3481 tatttctatt atagatgaac ttcctccagg aagacagcca atagaaacaa ttgctattga
     3541 aaaaagtaag cgagatagag catataataa tcttgtaaga agagaggttg aatcaggaag
     3601 acaagtgtac attgtatgtc ccttggtaga agaaagtgaa gccatagaag ccaaatcagc
     3661 agttgaactt gttgaggagt taagagcgga atattttcac gacttaaggc ttgggttgct
     3721 tcatggtaaa atgaagtcaa gtgaaaaaga tgaagtaatg agacttttta aagataaaga
     3781 aatagatatt ttagtttcaa caacagtaat agaagttggt gtcaatgtgc caaatgcaac
     3841 attaatgata atagaaaatg cagaaagatt tggacttgca caattacatc agcttagagg
     3901 gcgagttgga agaggtagtc ataaatcgta ttgtgtacta atttatgatt ctaaaacaga
     3961 tgtatgtaga caaagaatgg ctataatgga agagaccaat gatggtttta agatttcaga
     4021 gaaggattta gaaataagag gacctgggga attttttggg acaaggcagc atggtcttcc
     4081 agaacttaag gtagcaaact tatttaagca tataaaaata ctgaagttag cacagcaaga
     4141 agctcgatat atattgggtg aagataataa tctacaatta aaagaaaaca tggcactcaa
     4201 aaaagaaatt atagataaat ttaaagatac attgaaagaa atttcattaa attaatttta
     4261 aattgtgtta aaatattact aatgtaataa tgtgctgaag ggagattgtc atattgagag
     4321 taatttcagg aaaagcgaga ggattaaaac taaatactcc aaaaaatgaa gatgtaaggc
     4381 caactacaga tagagtaaaa gagtctctat ttaatatgat aaattcatat ataatggaaa
     4441 gtgaagttct ggatttattt gctgggactg gttctttagg aatagagtgc ttatctaggg
     4501 gtgccaagtc atgtactttt gtagatatta gtaaggaaag catagatatt gttaagtcca
     4561 atataaaaaa ggcaagagtt gaaagtgaaa gtattatttt aaaccttgat tttaagactg
     4621 caatagataa acttaaatta caaaatagta aatttgacat aatttttatg gaccctccgt
     4681 attataaaaa tatgtttata gaagctattg aaaaaattga taattctaat ctattgaacg
     4741 aagatggaat aatagttgta gaacatgata cgaatgattt atttccagat aagatatgta
     4801 aattggagaa aactagagat aagaaatatg gaaatactac attaactttt tataagatgg
     4861 aggcataata tggaaaataa acctagaaaa gctatatttg caggaagttt tgacccaatt
     4921 actaatggac atttagatat tatttgcagg gcttcgaagt tatttgacga attacaaata
     4981 ggagtattaa ataatcctaa taaaaagggt ctatttagct ttgatgaaag agtaaaactt
     5041 atagaaaaaa gtacaagcca tttaaataat ataaaagttg tgacttttga tggtttatta
     5101 ataaattact gtcaggaaaa tgggattgga gcattagtta gaggtgtgag aagtggtgct
     5161 gatgttgatt atgaacttca gatggcacat atgaatagag agcttaatcc agatatagag
     5221 actataattt taccaagttg tacaaaatat tcatttataa gttcatcttt aataaaagag
     5281 gttttgctct ttgatgctga tataaaaaat ttggttccaa agattgtttt ggaagaatta
     5341 aagaaaaaaa ctagtggggg taattgatat atgaagatag atttagaaat gattgaacta
     5401 tttgagcagt tagaggagat atttagaagt gcttctacaa tccctttctc acataaatgc
     5461 acagtggata aagatgaggt tttagcaata attaatgata taagaacttt aataccagaa
     5521 gaagtaacac aggcagtatg gattaataaa gaaagaaata aaataataag tcaagctaag
     5581 caagatgcta caaatatagt tgaacaagcg aaaaaagaag ctgagagaat acaacaagaa
     5641 tatcaagata atatagagga attaaagaaa aattctgaag atgtagtaaa ggcatatgta
     5701 gaatccagtg aacctgttgt tcaagcagac caaagagcaa aagatatagt tgatagagct
     5761 gagagaatag ccaatgagat aagaattggg tcaattgaat atgcagagga tgtgctttct
     5821 agtgttgagt ataatttaag agaaatatta gaagaagtaa aaagagataa agctgaactt
     5881 agacctaaaa aataaatttt aaataaataa aaatggagct atcacacaaa aaattccaat
     5941 ttatgtgtga tagctctctt ttaatatagc aattttttgt tatataattg tgctttttag
     6001 attacttata tcttattttg atattataat gtagtttaat cttttatttg ttgaaatcaa
     6061 cttatttatt tgtataaata atataggtta ttttcaaatt tttttaataa ttttaccact
     6121 gtcttctttt agattagagt tagactgtgc aaaattataa aataatacta aatcatgtgc
     6181 aattatttgg tatggcacta catgtagaaa atatagataa taaaattaag gaggtagtat
     6241 gaaggaaagg gctaaaaaaa tattagattt tattattaaa aataacaatg taacatcaca
     6301 agaactacaa gaaaagttta atgtttcaaa gagaactatt tattacgata ttctagctat
     6361 aaatgaacaa ctaggaaaaa gtggtaatat aaaaaatgta aaacacaaat ttatatttga
     6421 aggtaattta tgtgatgcaa ggaaaataat ttcaactgaa gaagataaat ttttagatag
     6481 tgattacaga aaaactttta tattaaacaa gatattactt ggcgaaaaaa tatcaataga
     6541 aaaactaaca aatgaaatgt tactttcaaa aaacacagta gtacaaacaa taactgatgt
     6601 aaaaaaatac cttcaaacaa tggggttaag attagagtat aagggaaagt acaaaattat
     6661 aggtgatgaa tacgttatta gagagctgtt tctgataatt gttcaagaaa atatattgga
     6721 aattaattct ataagtgagg aagtaagtag tttcgataca aaaggacata taaaacttac
     6781 tgattattct ttattaaatc taactaagtt tgtggaattt ctaaataaaa ggataagaga
     6841 tgggaaaaca ttatactcat ataaatatct aaatgaagct aaaaaaatta gttactttag
     6901 taattgtaaa gaacttttat gtgaagaagc taatgaaaat gaacaagcct atatatgcac
     6961 ttacataagt tcacttccca gcttaaatag tgaagttaag gaagatgttg ttgaagaata
     7021 tgtagataaa cttatagata agtttgaagt aaatacagca ataaaattag aaagtaagca
     7081 tgagtttaag aaaaatattt taaggcacct ccattcttct tacaacagaa tacgatttaa
     7141 gtttcctatt agaaatccaa tgttagatga gactaagtat aaacatgagt cactttataa
     7201 aattataaaa tcaattatag aaaatgaaga agagtttcct gtatttgagg ggataagaga
     7261 agaagaaata ggatttatag cagcgtattt tggaggatat ttaagagggt ctagggataa
     7321 tggtctaaga agaaataaag tcttactagt ttgtcctaat ggtcttatgg tatcaaagag
     7381 tttggaaata caactatata aatacatacc aaccatagaa atagtaggta tagtatccat
     7441 taagcaacta aaagaagtaa atgtatacta cgattacata attacaacta tagatataca
     7501 aaatgtaaac aacgtaattg ttgtaaatcc tcttttaaca tcatcagatg ttcaattact
     7561 tatgaacaaa ctaataagtg taaaagaaaa cgagaagtat ttcaatcttg aattaataat
     7621 acaagctata agaaaaaatg gagttatcaa taatgaagaa gcactaaaag ctgatttatt
     7681 aaacataata cacaagatag atgaaggaga gatgtatcaa ccaatgttaa aggaattaat
     7741 taatgcagaa agggtcaata taataaaaag tgttagagat tggaaagaag caataaaaat
     7801 agcctcaaag ccattgttag aagataactc tatagaagag ttatatatag aaaatatgat
     7861 aaagtcagtt gagaaatatg gaccatatat tgttttagct gatagatttg ctctaccaca
     7921 tgcaagttct aaagaaggag taaacaagct tgctatgtct ttactaatag tagaagatga
     7981 agttgattta ttaggaaaac cagtaaatat atttatggta ttagctgctg tagataacac
     8041 tactcacatt agagcattag catcactatc agagatgatg tacgaggaag aaaatgtaaa
     8101 actaataatt aatggtgata aaagttcaat actagaactt ataaataagc aaaattagga
     8161 ggaatgaaaa atgaagatat tagcagtatg tggttttggt gtaggttcat caatggtatt
     8221 aaaaatgaca atacaaaagg ctctaaagca gttaggtata gaatgtgaag tagaaaatac
     8281 agatataaat tcagctagag gtgctgattg tgactgtata ttcacaagtc aagaattgtt
     8341 aaatgaatta aaaggaactt gtaatgtaga tgtatatcca gttaaaaagt acatggattt
     8401 agcagaagtc acagaagttg ttcaaacttt tttaagtgat aaaaatgata agaaatagta
     8461 taagttttaa aaagtaaatt taagttaatc agaataaaat aaaaacttac taaattcaaa
     8521 aatagtaaga aagagaggag ggatttagtg gtagaaaact taaacagttg acctatcact
     8581 aaaaaatata atgcttgatt ttatttcaaa taatatttta cgtaatccat ctatgttaat
     8641 tggattaata gcagcatttg gtcttgtact acagaagaag aaagcatctg atgttataaa
     8701 ggggtcacta cttgcagctt tcggaattat aattatggag actggaacag gtatgttagt
     8761 tagttcaata gcaccaatta atggagcttt ccaaagtata agtggtggtg cagtaacaaa
     8821 aggtttaagt gatgttactt ttactgcaag ttatggtgga attataggtt tagcaatgtt
     8881 tgcgggttta gctattcacc taatgatagc aagatttact cctattaaga caatcttttt
     8941 aacaggtcac atgctttatt ggttcccatt catatttgta gcttcaggag ttgaagctgg
     9001 attaaatggt ggagtattaa tagcttttgc agcagtatta tcagcactct attggtcaat
     9061 aatgccttgg ttattaagaa aatatgtgtt tgatgttata ggagatgatt cttttacatt
     9121 aggtcatcca tctggttgtt tagcacttat atcaggattt gttgctaaat tagtaggaaa
     9181 taaagaaaaa tctacagaag atataaacat acctcaaagt ttatcatttt ttagagaaat
     9241 atctataagt ggtggaatgg cagtgttttt aatgtttata gttgttggga tagtaatacc
     9301 aggtgcgttt aaagatagta atgagtttat tggaacgtat gcaataaagc aaggtctttc
     9361 ttttggagca ggtcttataa taatgcttca tggggtaaga atgctaataa atcaaataat
     9421 gccagcattt caaggtatat ctgaaaaagt tgtgccaaat gcactacctg cttttgactg
     9481 tccaatatta tttaattata aaccaaatgc tgtattaatg ggattcttag ttgctatgct
     9541 aacatctaca gctatgattt taatatgtaa ctactttaat gtatttaatt tgctacttat
     9601 accacttgtt ataacttcat tctttgagtg tggagcagca gcagtaatag gagaatcaca
     9661 aggtggtata cgtggagcta taataggtac agctatagct gcaatattta tggtagtttt
     9721 agtaggaata tctgctgtaa tttactcagg aactattcaa aattggatac taatatttgg
     9781 aggtaatgac ctttcattat ttggtataat cagtaggttt ataggttcac tatttggagg
     9841 aatattatag atatgaaatt taaatacata gatgagataa gaagattaat tgatataata
     9901 gaaaacgaag aaaaagtcaa tatggaaaaa gcagtacaaa tctttgttga agcaatagaa
     9961 agtaaaaatg ctatattttc atttggagct tcacatgcag gaatattaac agaagaatta
    10021 ttctatagag caggtggctg tgttcttata aatccagtat ttgcaaaatc tctaatgtta
    10081 gatacagcgc ctataactca cacaagtaag atggaaagat tagaaggata tggtacagct
    10141 ctagctgata aaactccaat taaaaaagga gatgtagtta tagttcattc agtatctggt
    10201 agaaatccag taagtataga gtttgctatg aaagctaagg aaaataaggc aatagtaata
    10261 tgtataacta atttaagtta ctcaaaaagt gtatcttcaa gacattcttc aggaaaaaaa
    10321 ctttatgaag tatgcgattt agtgatagat aatcatggtc aaaagggaga tgcctgtgta
    10381 gagatagatg gattaaacca aaaagttagt ccaacttcta ctgtaatagc aactactgtg
    10441 atgaactcta ttatagctca agctactcag gaattagtta ataaagggct aaagaatcct
    10501 ccgattttct atagtgcaaa tattgatggt ggagatgagt taaataagaa gatttttgat
    10561 gaatataaaa gtgtaattca ttatgaatat taaggttaaa aaaatatgtt aatgaacttt
    10621 gaagtttatc aacaaagaat attaataata tataataaat gctatcattt aaaagctgta
    10681 ggtaaaaatc tacagctttt tattattgta gattaaaaag atgcgtaatt aaattttaaa
    10741 ttggagaaaa taaattggaa ggtatcaatt ataaatatta gaaacgttgt catagaaaaa
    10801 aactatatta aaaaaaagta catagaaaaa actgattaga caataaatac atgctttgat
    10861 aatattttaa atggagtgaa aatgtgtaga attataatga aaaaagaaaa taaaaatgaa
    10921 aaaagaaaat aaaatggagg gaataaaagt gggtatgtta aaaaaattat gttcactagc
    10981 tatggtagca attatgacta caacacttat aacagggtgt tcaagtggaa atggaaaaga
    11041 ttcaaaaaag gatggcgaaa aagaaaaact agttctttgg atgccaccag tagaaaataa
    11101 tatgaaggaa gtttgggacc ctattttaga taaatttgag gaaaaaaata actgtgaagt
    11161 agatttacag ataattcctt gggataatta ttctgaaaaa tttgcaacag ctataagtgc
    11221 tggcgaaggt ccagatgtag gatatatgta tgcagaaatg tatccacagt ttatagaaag
    11281 tggagcagta gaagatttga ctaactatgc aactaaagag gataaagagc aatctattta
    11341 tataaaaaca tctgaaatga tgggtggaat gtatggtatg ccattccaag cagcaaatcc
    11401 aggggtatta tactataaca aggatatttt agagaaacta ggagaaaaac ctcctaaaac
    11461 atgggaagat tttaaaagaa tttgtaaaaa agcaacgcaa gatactgatg gtgatggaaa
    11521 gatagaccaa tggggattag ctcagggatg gggagctaaa acttttggta acttaaactg
    11581 gaactggtat ccttatttat ggcaagctgg tggagatata tttaatgatg atttaaaatc
    11641 ggttaaattt aatgataaga gtggtttaga agcagctaag ttcttaaaag aattacaagc
    11701 atatgtgcct gaagattctt tatctaaaga tagtaatgaa atgatagaaa gtgtatttgg
    11761 accagggaaa gcagcattta caataatgtt atcttctgct gcaacaagtg tatttgatga
    11821 atcattcccg gatttaaatt ggggatttgt aactggacta gaagataaga aagcagcaac
    11881 ttttggagca gtagaccatt tatctttaat ctcatctgcg aaaaataaag aacttgcata
    11941 caagttaata caacatatgt taagtgttga atcaatgaca gaatttcata aagcaatacc
    12001 aagagcacca ataacaaaag gtgaaccata tcaaggtgat gaaagattca aagaaatggt
    12061 ggaaaatgac aaaaatgtat atagaccatt agtagtagga cctcatggag ttgaaatata
    12121 tgaatattta tggaaagaac ttcaaactat gatttcagga gataaaactc caaaacaagc
    12181 gttagatgat gctgcaaaat attcaaatga tttattagca caataaaagt ttaaagctgt
    12241 aatatgttgt aaagtacttt acagattaaa attagcattg tatttataaa tacaatgcta
    12301 atatttatat tggagaggat aaaatggaaa acttagttag agagtttgaa gaaaattcaa
    12361 aaagaaaaaa aacaaaatta aatattaaac catatatgta tatattgcca ttgggaataa
    12421 ttttagtggc gttttatgtg ataccaataa taatgtcaat atactttagt tttacaaagt
    12481 ataatattat tagtccagct acttttatag gtttagaaaa ttataaaaaa ttatttacag
    12541 atgaaacatt aaaagtatct attataaata ctattaaatt tactgttgtt gtagtacctt
    12601 gccaaactat attatcattg attttggctg tttggattac aggaaaagga aatagtaaaa
    12661 tagcttcatt tgctaaaggt gctatattta taccagtatt atcatctatg gttttgatag
    12721 gtatggtatg gagggcttta ttgaatggag aaggttctat tatatatcag gtattaggtg
    12781 cctttggaat agaatcatct aaacttttag gagatagtaa gacagcatta cctacactta
    12841 tgtttatatc tatgtggaaa aatatagggt atttcatggt aatttatatt tcagctataa
    12901 tgaatttacc aaaacactgc tatgaagtag cgaaggttga tggggctaca aaacttcaag
    12961 aatttataaa aataactgta cctttattga aaccaactac aataatggtt gtatttttag
    13021 ggtcgatatg gtcattacaa gtatttgact taatttatac tgtgacaggt ggaggtccag
    13081 gtatatctac tatgagtata gttatgcatg catttaactt aaactttaaa aactttaatt
    13141 ctggatatgc aatgactgta gcaaacgtat tatttttgtt aatagcagta gtttcgattt
    13201 tacaaaataa gcttgtaaaa cgagacaatt cagattttta gaaaggtagg tataatatga
    13261 aaacagcaag aagattatta agtgatggtt tacttttatt tatagcgtgt gcaagtttgg
    13321 taccttttat atacatgttg ataatatcat tgaagataac atataactca tatagtttgg
    13381 atatatcttt ttcaacagta acccttcaaa actatataga tatttttact aaaaaaggat
    13441 ttgcacaata tttttttaat acagcaatag tatctttttc aggtgtatta ttaaatttag
    13501 tatttagtac attagcagga tattcttttg cgaagatgga ttttaaaggt agtgataagt
    13561 tatttttatt tatgataatg actttaatta taccttccca agttacaatg ataccactat
    13621 atataataat gaaacactta ggatggataa atagttatct tgcacttatt atgccaatac
    13681 caactgcatt tggcgtattt ataatgagac aagctatttt aggagtacca aaagagttat
    13741 tagaatcagc aaagatagat ggttgttcgg attttagaat tttaatacaa atagtgttgc
    13801 ctttaattaa accagcatta attacactag caatatttac ttttatggga gcatggaacg
    13861 agtttatgtg gcctcttata gctacaacta aagatgcaat gagaacatta acagttggat
    13921 tatctactct taagacattc cagataacta attatggaca gatgatggca ggggctacaa
    13981 taacattttt acctccattt attttctatt tgattttaca gagtaaattt gttgaaggtg
    14041 tgtctttgtc tggtataaaa ggttaaatag tctaatttaa taatatataa agaaacttat
    14101 ataaatatgg aggaatttaa actatggaaa tttcatatgt actgaaagat tgcacattca
    14161 aacacaataa atactcagtt gtagaagctg aaacttggaa agataaggat ttggatattg
    14221 tagtagctaa aggtgaaaaa tttgcatttc aaattatgtt aaaagcaaca gaagaattta
    14281 attgtacaat tgataaaagt agtgctatat catggaaagg cctgggaaat agagtaaggt
    14341 tagcattaaa tatgcctaat agtttagaaa ataattttag tataaatata ttaggatatg
    14401 ttcaagatga tacaaaggca tttgtgaatg atgctatttt aagggataaa gatgtgttag
    14461 tagagcaata tttgcctcaa acattttgga ttgaaggtca agtaccagaa gattttgaag
    14521 aaaataacct tgatataggt attgatatat ttaaaagctt tggatatgaa gatgaagaaa
    14581 aagtttgtac aattgatgtt cctgtaaaag taagaaatgt tgtgctaaag cctttagatg
    14641 aaagcaagtt ctttttagat ttatggcaac atccaagctg tttagctaga atgtataaag
    14701 ttgagttatg gtctgatata cattttgaaa tagtcgataa ctatttaaaa gaattagcat
    14761 ctttaggaga aaaagttgca acagttatag tttcagatta tccatgggca gggcaaagtt
    14821 gttataaagt ttataaaaat ccatcaaact tatatgaata taacatggta agtgtatcaa
    14881 aaggattgga tggaaagatt aaatgtaact ttgagagtat ggataggtat ataggcatag
    14941 ctgataagta taaaatggct aaggagatag atttatttgg tctattaggt aattggtgtg
    15001 ctggtgagtt tggaaatcct gtagaaggtt ataaggaccc tataagagta agatattttg
    15061 atgaaaagga taaagtattt aaatttataa acaatacaaa tgatttaaaa gaatatatag
    15121 gattagtatt aaatcattta atagagtgtg gattatggga cagagtaagg attatagctg
    15181 atgaaccaaa taatccagaa gtagtcaaag agtgtataga atttataaat tctactgtag
    15241 gtactcatca agttaaatat aaatcagcaa ctcacgacca aaacttttta gacagagcta
    15301 aagatgaaat tgatgatatg tcaataaatt taaaacttac tatacaaaat tataaagata
    15361 tagaaagtct taagaaaaaa atcaatgaca agggtgggat attgacttgg tttgtatgct
    15421 gttttccaga aaaaccaaat agttttttaa gttctccttt tgtagaaaat agaataatag
    15481 gatggtatac ttattacttt ggtcttgatg gatttttaag atgggactat aatttatgga
    15541 cagaagaccc ttggaaagat tcaagttaca aattccctat ttggaaagct ggagatatgt
    15601 tctttgttta tcctggaaaa gatttaaagc cagttagaag tgtcagaatg gagaatttaa
    15661 gatttggaat acaggatttt gagttattta caatgttaga aaaagaaaag gtaagagagt
    15721 atatagaagt tgagcttatg caagaattat taaataaaaa agaaaatgct gaaattaaag
    15781 gttttggtga catagaacta ggatattcac ttgataattg gagatatgat aaagttaaaa
    15841 aatatgtatt agagttgtta gacagagtat aaaaaatata agagtgtctc aaaatgaact
    15901 ttttagttca tgaggcactc tttttgtatg aaatcaatat agtttcattg tttcaacaat
    15961 gaaaaatagg attatttcta ttctaagaca gccctttagt tttttagttg tattcaatgt
    16021 tttaaaacta actataaacg ctataaagtt tataaatgac aataattata tataacatga
    16081 tgtactttaa tttgctataa tagggattga ataatattat atggaagata acattgtttg
    16141 gggggattaa tataaaaaga ataggtatta ttataatgtt ttttttaagt atatctttta
    16201 ttggatttta tcttgtaata agagataaca gtgatacagt taagatgcaa cgagggataa
    16261 atataggtaa tgcactagaa tcacctaagg attttccgtg ggatgtaaaa atgtcaaata
    16321 agttttttga tgatataaaa gatgcaggtt ttgacacagt acgtatacca gtaaggtttt
    16381 ctgattatac gtcagattct gataatttta aaattgatga agaatttttt aaaaagattg
    16441 ataaatatgt agattatgca ttggataaag acttaatagt tgtgttggat ttacaccatt
    16501 ttgaagaaat tatgaaagaa ccaagagttc ataaagaaaa gtttttaaaa atatggcaac
    16561 agatagctaa taggtatcaa aaatatgata aaaaattggt atttgaatta ttaaatgaac
    16621 ctaaagaaaa tttatcttca caattactaa acgaatacat tgaagaagca ataaagataa
    16681 ttagaaaaac taaccccaaa agaactatta tagtaggacc atataatttc tatcaaattg
    16741 attatttgaa tgaattaaat attcctaaag attctaatat agtagtttct tttcactatt
    16801 acgagccaaa tgattttgca tttcaaggaa atatctatca taagggattt gagcacttaa
    16861 gcaatattac ttgggaagga acaaatgaac aaatggatta tttaaaaaaa aggtttgata
    16921 ctgtggaaaa ttgggcaaat aaaaataagg taaaaatctt cttgggtgaa tttggaataa
    16981 caaaagaggc accagaagtt tcaagaagag catggataaa agctgtaaga gaagaagctg
    17041 aaaaacgaaa cttttcatgg gcttattggg agcttgcatc tggatttggt atatacaatc
    17101 aaattgaagg gacttgggat agagatatat taagtgcatt aatagaaaag aggtgatttt
    17161 atgaagaaaa attcaaaaaa gatacttata actttaacta ttattactaa tgtcatatat
    17221 atattgtgga gaatttttta cacagtacct aaagaagaag ggaagtttgc cttaatatgt
    17281 gccataatac ttctttttgt agagataatg ggtatgatgg aaatgtttgt gcattattat
    17341 ggtatgtcaa atattgagta tcctgaaaaa ccaatcataa gtgaagaact ttatccacat
    17401 gtagatgtat ttattgcaac atataatgaa tctgttgatt tggttagaaa aactgtaaat
    17461 ggatgtattc atatgcagta tccagataag aaaaaggtac atatatacat atgtgatgat
    17521 ggaaatcgtg aagaaatgcg tattctagca gaaaaaatgg gtgtaaatta cataactaga
    17581 actgaaagag aaggagcaaa agctggaaat ttaaataatg caatgcaaca tacaacttct
    17641 cctttgattg ctacatttga tgcagatatg ataccaatgc atgacttttt aattgctaca
    17701 gtaccatact ttttaaaaaa tgagcaagct aaaaaagatg gagaaaaaga ggagtatgaa
    17761 aaggttggtt ttgtgcaaac tccacagagt ttttataatc cagatttgtt ccaatttaat
    17821 ctgcactctg aaggaaggat tccaaatgag caagattatt tttacagaga tattcaattg
    17881 gctagaaata ggacaaattc tgtaatttat ggtggtagta atacagttat ttcaagggaa
    17941 gcacttgaag aagttgatgg attttatact tattctatta cagaagattt tgcaacaggt
    18001 atcttaattc aaagtaaggg gtatagatgt tatgctattc cagaagtaca tgcatcaggt
    18061 ttatctccta cagatttaaa aagtcttatt aagcaacgtg aaagatgggc acgtggatgt
    18121 atacaaactg gtagacgtct aaatattttg tttaggagag gtttaggttt ttggcagaaa
    18181 ataagttata tttcttcaat tacttattgg tatgcaagta taaaacgctt tgtatatata
    18241 atggcaccta ttttattttc tgtgtttaat gtgattgtag taaaatgtac gttacttcaa
    18301 gtattggtat tttggttgcc aatgtatatt ttaagtagtt tatctcttaa aatattttct
    18361 caaaatataa gaaatactag atggaccaat atatatgaaa ctataatgtt tcagtcttta
    18421 atgccagcag taatacttga aacgtttgca atatctaaaa ataaattttc agtaacaaat
    18481 aagagtaaat tagaagaaaa tagaatgtat aagtttttac agggaatacc ttattttatt
    18541 tacatggtct tatctatcat aggaatttta aaaatgtttg tagcaatatt taaaatgagt
    18601 tcaatgacat attcagttgt attattttgg ttgattggaa acctttttaa ccttgttatg
    18661 gctacattat ttatatcagg gagacagcag ttaagaaagt ctgagcgtta tattgctgaa
    18721 attgatttta agttaaagca aaattcttat gttctttctt caaaaacaat tgatatatca
    18781 gaaaatgggt ttgcattttt gctagaaaat ccagaatata tttcaccaga agaagagttt
    18841 gaggtagagt ttagagaaaa atctggaaat gaaatgtata tagccaatat gaaagcaaag
    18901 attgttaatg ttgtggaagt aaattcaaag tggaaatatg cagcttatat tacacatatt
    18961 gaagatagtg aaatagataa ttggatgtgt attgttcacg atagaatacc tactttacca
    19021 atgacaatat ctaatcaact aggtttcttt gatgatttgc aaattaatgt gaaaaaacgt
    19081 attgaaaaaa ctagaacatt atcacgaaga agtccaagaa tcaatatgaa ttttcagatg
    19141 gatataaaaa atacaggtaa attaagaata gtgaatttta attatcaata tgtattatta
    19201 aattttgaga ataaaagtat ttatcctaaa gaaatagcat tggaaattaa tgaaaatatt
    19261 gtgttagaat gtgatttgtg tgagggtaaa attgatgaaa gaggtatctt atataaagta
    19321 aataacattg acagcataat gcaaaatttc tttttaagag atgaaatgat ggattggata
    19381 ttacaaaata agacaattct tgtttcaaag cctagtgaaa agaaggaaaa aagtatagat
    19441 gagtttgaac ccatggaata tatttaggag agatgaaatg aagactttaa aagtgttttt
    19501 ttgttctaca aaatatctta ttttggtgtt tatttttttt ataaatacta cttttataag
    19561 ttcagcaaca agtgataaaa ttttagattt gtcctttaaa aagatagaga ctgacttaaa
    19621 ttctaagatt acatatgaag atacaggtgt aaaaatagaa acggatagtt ctaaaagcga
    19681 taaggaacgt tatttatata tttaccaaaa tataaaagaa aattggagca tgtataataa
    19741 tttttatatt gaaattcaaa ataaaaataa aagttctcag agaataaatt taagcataca
    19801 aagtaaaaat atgcttgaat ttagattaaa agaaggtagt gaagtatttt tagaaggtaa
    19861 aaatataata tattcagata aaataaaaga aggatgcata gaagtaccag gtgaatttga
    19921 aggcaaaatt tatgtgaact ttaatagcct tataaatgag gaaagtaatg ttgtgctgga
    19981 ctcaaatatg ctttcaaaca ttgttagttg gggaattacg tttattccat ctgatgaaga
    20041 acataatatt gttattataa aaaagatatc tttattgtct gaagagaaat taagattttt
    20101 aaataatatt aaaataattg gcgatgaaga agtacaaata ccagtattgg gtcaaagtat
    20161 aagtcagtat gaagtattag gtcttaaaag tgattctaaa attaagtact ctcttatggg
    20221 aaaacaagat aatgtaagca tatctcaaaa aggtaaatta acattaagta ataaagccaa
    20281 acctggacaa attattttac aagttaatgt tgatgataag tttaaaattg gaaagaaaat
    20341 aacattaact gagtcttgga gtgttaataa aaaagataag gatggtgttc catatacatt
    20401 agtatatcct gagcaatcac caacagtaca agatatgaaa aaaataaact ttatgaataa
    20461 catcataacg tttgttcgaa ttttatttgt atctctagta ataatatgct ttggaatata
    20521 tttatattgg aaaaaatgtt caaaaactaa gtaaagagag gaggttagat tgtgttattt
    20581 tcaagtttaa tttttttatt ttatttttta cctataactt tggttttata ttatgtattt
    20641 aggtttaacc gaacgataca gaacatgata ttgcttgctg ttagtttatt tttttatgct
    20701 tggggagagc caaaatttgt tgttatcatg atagtttcca taataatgaa ctatatattt
    20761 ggtttactgg tagatagata tagggaaagt aaaataaaag taaaagtttt tttagttttg
    20821 atgtgtgcat acaatatagg tgttttattt atatttaaat atctagcttt tgcgctaaga
    20881 aatattagtg aacttattag tactgaattg actataccta gtattgtttt acccatagga
    20941 atttcatttt ttacatttca gggaatgtct tatgttatag atgtatatcg tagacatgga
    21001 gaagtccaaa agaacccttt ttatgtggga ttgtatatag catttttccc acaattaata
    21061 gcaggtccta tagttagata tgagagtgtg gcagaacaaa ttctcaatag aaaagaaact
    21121 tggaataaat tttctattgg gacttgtagg tttataacag gtctaggtaa aaaagtatta
    21181 atttcaaata acatggctat agtagcagac tatatttaca ctatgaatag tcaaggagaa
    21241 atagctgcat cacttgcatg gcttggttca atagcctata ctctgcaaat attctttgat
    21301 ttttctgctt attcagatat ggctataggc ttaggtctta tgtttggttt taaatttgaa
    21361 gagaacttta attatccata tatatcaaaa tcaattagtg agttttggag aagatggcac
    21421 atttctttgg gaatgtggtt taagagctat atatactttc cgcttggagg ttctagagta
    21481 gcaaataaag atattatgat tagaaatatg tttatagtgt ggttatttac tggaatatgg
    21541 catggagcag aatggacatt tgtaatttgg gggattttaa actttgtttt cctaattata
    21601 gagcgattta taatgtttga aaagattgaa aatcacaatt ttataaaaca tatttatgct
    21661 ttattagtag ttaattttgg gtgggtatta tttaggtcac ctaatttaaa agaagcatat
    21721 aattatttta aagctatgtt tggaggcaat ggagctatat ggagtgatta tacatatatg
    21781 tttttaaaag aatactgggt tttctttata tttgcattta tttttagtgt acctattgca
    21841 aagaaaatca ataagtttgt tgttgaacaa gctaaatata gtatgatatt taacgtattt
    21901 tatccaatct cagctatttt attgtttttt atttctgtga catatttagt aactggaagc
    21961 tataatccat ttatttattt taatttttag ttgggaggaa aagtatgaat agatttttta
    22021 aagtaagatt aataactgca attatgttct taattatttt attcgctttc tctatcttta
    22081 atgtttgtta ttctggaaaa gatacgatac aggaaataaa aaattcaata gctgaaaaaa
    22141 gtagtttaaa agatacaata tcatctattg ataatacagt gaatgacaaa gtaatataca
    22201 aaaatacgtt cattgaaact tatggctatt tacaaaaatt aatgggtaaa aatgagtttt
    22261 caaaatttag tgttgtaaaa gatacttctg gaaagatgca ttatacatat tttgctaaag
    22321 ctccaaatcc agttggtgtg atagcagata gggtaagaaa attttctgat gaaatggaaa
    22381 agcaaaacac taaattggtt tacctaatga ctccagataa gtatataaaa ggagtgacaa
    22441 aatttccaaa aggaatacct tattcttata gtaatgagac agcagataat tttttaaatc
    22501 aactaaaaaa gtataatgtg gactatattg attttagaga aaatatttta aagagtggta
    22561 ttccaaaaga tgatttattt tttaaaacag accatcactg gaaagtagaa acttcttttt
    22621 gggcatttgg agaattagtt gagcaactta ataaaaaata caatatgaat ttagatgaaa
    22681 atcattatta tagagataag gacaattata attcaattgt atatcctaag tcatttcttg
    22741 gttctatggg aagaaagact ggtatcttat atggtggtat agatgatttt acattaattt
    22801 atcctaaatt taagactaat tatacttatt atacagattc taaatctcaa aaatttgaat
    22861 taaaaggaag gtttgaagag agtttaatat tatcatatcc ttttaatgca gaccttgatt
    22921 taatggatgg tcaatcagat aagtatttta catatttatt ggggaacaga ccattagtta
    22981 aaataaaaaa tatagaaaat ccagatggat taaaagtgct gtttgttaaa gattctctaa
    23041 ttgtaccaac agcagcattt ttttcctctg tttgttcatc tatagatatg atagacccta
    23101 gatattatga tggagatata ctagaatatg caaaatccca tgactatgac tttgttttta
    23161 tatctgtata tccccaaaat cttacaaaag aattttttcc gttttgtgag taaatttcta
    23221 aaaaagtttt ctgataaaat aaatggctaa ctggtaaaaa gttagccatt tattttgagt
    23281 gttattctaa gaaatatttt ttttactaaa tacttcttta tctatttttc caagtgattt
    23341 tcctacagta attgatgata ccatagcacc attaacattt atcatagtac gtcccatatc
    23401 tagtataggg tctattgcaa gtataccacc aactaatgga aaataagaac caagaccaac
    23461 tccagagata acaactgaaa cggccattgt agcagttcct ggaagaccag ctattccaaa
    23521 cgaactaatt gttataacaa ttaacaacat aacataaaag ctcatatcca tgtttactcc
    23581 agccatattg gcaagtgtta cagccattaa agcaggatat atacctgcac aaccattcat
    23641 acccatattt gcacctaaac ttgctgtaaa gcttgataca ccctcatcaa ctccgtgatt
    23701 ttgtactaga ctttctatcg ttacaggcaa tgttcctaaa ctagaacgtg aagtaaatgc
    23761 cagaagtaaa gcttcagttg aattttttat ataagtaatg ggatttagac catttaaagt
    23821 tataaaaatt aaatgtataa taaataatat tgcaactgat atataaagag ctaatataaa
    23881 ctgtaaaaca gatactattg aactaatacc ttgtgaagtt attgtatttg caagcagagc
    23941 aaccacagca taaggcataa atttaataac agtcatagac acacttacaa ttattttgta
    24001 agatgcttct ataaaaccta taaatggttt tattgtttca aaatgttttt tacttaatct
    24061 ctttattgag gtagctataa atgtagcaaa tattattgta gctacaatat ttccatttgc
    24121 catagccatt acaggattag atggtagtaa tcctcttaaa gtatccacaa gagagtttat
    24181 ttctttaagt tcttgatttt caactaaagt aggcatatta gctcctacac ctaacttcat
    24241 tatatttgca acgataattc caacaattgc agctatagca gtagtagcaa gaagcatacc
    24301 taaagattta aatgtcagag ttccaagatt gttatctttc atatttataa ttacttttat
    24361 aatggataag aaaactaaag gtactactaa catttttaat aagtccataa atccagaacc
    24421 aaataggcta taccacttac ttacttcttg tagccaaatg acttgagttg tatcattagg
    24481 aaaaccagca aaagcttgta ttatgattcc caatatgagt cctagtactg tagcatatat
    24541 tgttctcaat gaaaatttta tttttttctt ttcaaattgt ctaacaataa agaacgtacc
    24601 tagaagtaat attatgaaaa aaattgtttt aaaatctgta atcataagaa attgtgataa
    24661 aaatgaactt tccaatattt ttctcctttt atttaaaaat aaatttttct aagtttaaat
    24721 gatatcaata tattaaaaaa atgtcaatat tatatcacaa tttacttaaa tagagtaaaa
    24781 caagttgatt ttgaaaaatg tgattaagta cagaaaaata gggtataata aatgtttaaa
    24841 gaatttgaat tgtggtaaga aaataaaaaa tagcttttat aagatttgat ttcaaattaa
    24901 aatgtgttaa ataaataact aaaaattatt ataaaaaatg ttttcataga atatatatca
    24961 aatgaaaagc ttaaaataag tgaagaaatt aactagacat caaaggagag ataaaatgag
    25021 agtaataata attggtggtg ttgcagctgg tatgagtgct gcagcaaaat taaaaagaat
    25081 aaaacctgag tatgaagttg ttgtttatga aaaaactgaa atagtatctt ttggtgcttg
    25141 tggattacca tactttgttg gtggattttt taatgatgct gatgaattat tagcaagaac
    25201 accagagaaa cttagagaag ctggaattga tttaaatata tttagagaag tcgttgaggt
    25261 tgatagtgaa tctaagaaaa taaaagtaaa aaacataaaa acagatgaaa tatatgaaga
    25321 ttactatgat aaattgatga tagcaactgg agcaagaagt attatgcctc ctataaaaaa
    25381 cataaaatta aagaatgttt ctacattaaa aagtttatat gatggagaat atttaaaaaa
    25441 acttttaagt aatgaagata ataaaagagt gacaataata ggagctggtt ttatagggtt
    25501 agaagcagtt gaggcatgta agaaattagg taaagatgta gatgtaattc agttagaaga
    25561 tagaatattg ccacaagtat ttgataagga aatgacggat gtattagaag aagaaataaa
    25621 tagacataat gttaatttgc acttagatga aatggttgta gaactttgtg gagaagataa
    25681 agtagaaaaa gttataacaa acaaagggga aatagataca gatgtagtaa taattgctac
    25741 tggcgtgaga cctaataccg agtttttgtc aaatactaat ataaaaatgc taaaaaatgg
    25801 agctatagta gttgatgagt atggaagaac ttctgtagaa gatatatact ctgctggaga
    25861 ttgtgcaact ataaagaata tagtaagtaa tgaaaatgta tatgttcctt tagctactgg
    25921 agctaataaa ttgggtagga tagtaggaga aaacctagca ggaagagaaa tatcttatca
    25981 aggttcacta tcttcaagct gtataaaaat tatggatatg gaggcagcat caactggaat
    26041 tacagaaagg caagctaaag atttaggcat aaatgtcaaa tctaaattta tttctgatta
    26101 taatcaaact cattattatc caggaagaaa taaaatatat gtaaagctta tttatgatgc
    26161 agatacaaaa gttattttag gcggacaagt ggctgggttt aaggatgctg tccaaagagc
    26221 aaatgtattg gcagctgcta tctttggaaa aatgaccaca aatcaacttg gaatgttaga
    26281 tttatgttat gctccaccat ttgcaagaac atgggatgtt ttaaatgtag ctggaaatgt
    26341 atctaaataa tatttagatt atagctaata tagttgacaa gcaattaagg gaatgaattt
    26401 acctaaacta tttttatcat ggtaaaattc attcctaaat ttttattcca aatttttatt
    26461 ccaaattttt agaaataagg attccattaa attattcatc aaaatttaaa cgcaagctta
    26521 atctatcttc tccaagaata gtattttcaa aaacattagt agcattttct aaatacatac
    26581 taggtatgtc taaagaagga ctaaaatgag tcagtaaaag ttgtttgaca tttccaagtt
    26641 ttgcaagatt agcagcttct ctaaaagtca tatgtttgtt tctaacagct tttgatatat
    26701 ctaaatcatc accatacatg gcttcacata taaataaatc actatctttt atgaaatctg
    26761 gtattgattc tataggtctt gtatcggttg taagacttat cttaactccc tttctcaatt
    26821 ctcctaagac catatctgga gtgtattgtt ttgaatctaa aactatattt tgaccttctt
    26881 ggagtttgtt ccataatatt ttaggaactt cgtttttagt tgccttatct atatcaaatt
    26941 tagggtttct tctaaaatta aaactgtatc ctaaacactc tatagagtgt tctaaactga
    27001 ttgttgaaat ttctaaattt cttaaaactt tattatctaa agaaaaattg ccttgagggt
    27061 tttctataat ttttaaagtg tatggtacat attctactaa atttctcata gaacgtatac
    27121 aatcgactat tccaactgga ccaactatag ttaaatcact tgtacgacca ctattcccaa
    27181 ttgttgataa aagtcctaaa agtccaaata tatggtcacc atgtaaatgg gttatacaaa
    27241 tcaagtctat atctttaaag ccacattttt ttagcttcat agatacctga gtaccttcac
    27301 cacagtcaat tagtattttt ctacctttat agtttataaa tacagaggat agaaatctgt
    27361 ttggcatagg tacatttcca ccacatccaa gtaaagttaa atctatcatt ttttcccctt
    27421 tctaaaatta acacaaatct gttgtttgtt tttattatga tatcctatta taattatttt
    27481 aacattaaat ataacaataa atgtgtattt gagtcaagaa atattgtcaa ataaagtttt
    27541 tatatagcaa tgtataaaaa tttggaaaac gaaaagtgaa aattatattt aggagtattt
    27601 aaaggaggaa aatttaatga aagtattaaa gaaaattact attttgtcat taattacatt
    27661 aaccttagtt ggttgtagta acggagaaga gaaaaaagtg gttgaaggtt ctaagaaaac
    27721 tcaaaattct aaaaaagatg aacagcctat aatagtacat aaagatgcaa atatattgaa
    27781 agataggtat gagccaccaa aaggatttaa aagagttgat gtagaaaaag gtagttttga
    27841 atcatttctt aggaatacta agctaaaaaa ttatggagag aaagtaaagt attatgatgg
    27901 aagaactaag gaatcaaaag gtatttatga tagtgtattt gatgttgata ttggaaatag
    27961 agatttacat caatgtgcag atgcaattat gcttatgaga gcagaatact tgtatcagaa
    28021 taaactatat gatgaaataa gttttgattt tgttgatggt tttaaggcga agtattcaaa
    28081 atgggcacaa ggatatagaa tttcagtaaa agatagtggt tcaagctggt ataaagcaac
    28141 tgaatattca acatcttatg agagtttcag aaagtttatg gatatagtgt ttgcatattc
    28201 aggaacgtta tctcttgaaa aagaattgga gcctgtaaaa gttgaggata tgaaaatagg
    28261 agatgtgttt atagttggtg gaagtccagg acatgcaagt ataattatgg atatggcaga
    28321 aaatgaaaag actggtgaaa aggtatttat gatagcccaa agctatatgc ctgcacaaca
    28381 aacgcaactt cttattaatc gtaaaaatcc aaatttgagt ccttggtata gtttagattt
    28441 tgaaggtgat ttgacaatac ctcaatggac ttttaaaaga gaccagttga aaagatttta
    28501 aaataataat tttatataat aaaagaaaaa tatagatgtg aaaaaatgta attagattaa
    28561 aactaattgg atatggacaa aattaaattg atagataaat attaaaaatt acactaatta
    28621 atcttactat agtttaatat ttatctaaaa agttttatgt aaaatataaa ttttatatta
    28681 aagctaaaac taatttgagg aggctaattt atattgaaga ttagaaggta tttaattttg
    28741 gtaattataa ttctaattac aacaagtcag agttttattt cttatgggct agagcgattt
    28801 gaagaaataa ccatttttca cactaatgat atacatggaa gatatgctga aggtgatgac
    28861 catatacaaa taggaaatct agccacattg aaaaaagaaa ctccaaactc aattttagta
    28921 gatgcaggag attgtttgca tggacttcca atagtaaata tggatagagg gaaaagtgca
    28981 attgaattaa ttaaatgtgc tggatatgac tatattactc ctggaaatca tgactttaat
    29041 tatggaaaag atagactgtt tgagttatct aaaagtgcta atttaggaga gaatacttta
    29101 aaatttttat catcaaatat ttttgaaaat gggaaaaaag tttttgatag taatgatata
    29161 aaagaaatag atggaataaa aataggattt tttggactct caacccagga aacaaagagc
    29221 aaaactggat ttaaaaatgt ggaaggatta gagtttaaaa atcctataga aagtgcaaca
    29281 gaacaagtaa atgaattaaa aggaaagggt gccaatgtaa tagttgcaat atgtcatatt
    29341 ggtacaaata gtttaagtaa gccaaatagt atagatatag caaatgaggt tcaaggaatt
    29401 gatttgatta ttgatggaca cagccacact aagtttgaaa atggtaaaca agtgggtgat
    29461 acattgattg taagtgcagg acaatattta gaaaatattg gcgagataaa actaactttg
    29521 gatactaatg atgtagaaga tataaaaata gaaaataaat cagctagatt aattggaaaa
    29581 gaagaagcat taaagtataa gcttgactcc gttgtaagta aaaaggttga taaaataaaa
    29641 gaacaacaag aaaaaatatt agataaagtt ataggggtaa ctacaaatac tctagatggt
    29701 tcatatgaaa atgtaaggac aaaagaaact aatttgggta atttaataag tgacatttta
    29761 ctagataaaa ctaaggctga tatttcttta tttaatggag ggaatattcg agatacgata
    29821 gaaaaaggca atataacaag aagagatatt gtagatgtat ttccttttag caatactata
    29881 gttaccaaag aacttacagg agcacagatt aaagatgtat tggagcatgg agtaaaactt
    29941 tatccagaaa aaagttcagc ctttttgcaa gtgggaggaa tttcatatta ctttaatcct
    30001 aaacaaaaag aaggcgaaaa aataacaaat attcaaaaag aaggaaagcc attagattta
    30061 aataaaaagt atgtagttgc aacgaatgat tatatagcat caggtggaga tgaatttcct
    30121 tgtttttcaa aagagccagt actaaaggaa tttggaaatt tagagagtgc agtcattgaa
    30181 tatatagagt acaaaaaaga aatatcaaaa aatgtagatg gaagaattgg tattaaatct
    30241 aaagatgagt taataagcaa gaatcatgag agtgatttga tattaagtga aaatgaaaaa
    30301 aatatcaatg ataatgaaga gaatctatct aataatataa aaagctctga tagtgataaa
    30361 aataaaagct tagataaaac aagttctaga gaaagttcta atctaggaat atctaaaaga
    30421 gaagctaaag aaaaatctcc taaaacagga gatttaggtt tttcaaatag tataattata
    30481 tttatagttt caagtacatt gatatgttta ttgaatttta atcaaaaaga gttaaaggat
    30541 aaaaagtcaa aataaaaatt aatgagcaaa aattagtaga tagtaattta attttagata
    30601 atagtaaaca gcaaaggaaa ttagttatat aaatactaat ttcctttgtt ttatgtttta
    30661 acatgattac ttttaaataa aattgtattt tatgaaaaat aattatacta aatggcatag
    30721 tattatgggg atttttagtt tttattcaag taaatgaaat catattaaca acttctgata
    30781 tatttacaaa ttgataaaaa aatgatttta ttagtatgat ataatttagc tagtatgtat
    30841 gataatggag gatataggga tgaataatat attacttttg gaagatgaca aatctttaaa
    30901 tagaggaatt agttttaaat taaaaaaaga aggatacaat gtttttagtg catttggtat
    30961 agaagaagca aaaaatattt tcgcaaaaga agagatatgc ttaattattt ccgatatagg
    31021 tctacctgat ggtagtggtt ttgacttttg tgaggagatt agaaagaaaa gtgatgttta
    31081 cataataatg ttgacagctc ttgatgaaga ggtggatatt gtcacaggat atgatttagg
    31141 tgcagatgat tatatcacaa agccttttag cttgatggta ttaatatcaa aagtgaatgc
    31201 gcttatgaaa agagtaaata cagtaaaaaa ttatactcta ttagtttgtg atgatttatt
    31261 cttttattat atagaaaata aattaattat aagaacagat gataaggaag aagagataat
    31321 tttaagtaag acagagacaa aactattaaa atatttgatg gaaaattcta tgcagacatt
    31381 gactaaagag caactgttag aatctttatg ggatagtagt ggtaattttg tagatgataa
    31441 tacgattgca gtaaatataa gaagacttag acaaaaggtt gaaaaaaatc catctgaacc
    31501 taaatatata aaaacagtaa gaggggttgg atatatgtgg ggagaaagga gtataaaaaa
    31561 atgctaaaaa atatgaacct caaagatggt ttaagtgtga aagatgatta tataatgaga
    31621 agagttattg tatattctgt tttatctgta ctaatagtaa cccttgtatt tatacttttt
    31681 gaatatagca gattacataa attgtatgaa catcaaataa aaaatactca aaatgttgct
    31741 ggaatattga ttgaaaaata tcctaatgat gaaatagata tagtaaattc tatttataat
    31801 tctgattata gtaaggtgtc tactggagaa aaggcattta agaaatttgg ctatggattg
    31861 gaaaataaaa tgtcaaatga taaaaatttt agcttatact taaaatcttt ttttaaggaa
    31921 tcatttttta tttttttaat gatgtttata gtagttatag gtataatata ttattttata
    31981 agatacataa ataaaagatt gagtaaaatt tattttatag tagataagat gtcacaagaa
    32041 aactacttga aggacactac tgagtcagaa gaaactggtt atctagtaga atataatgaa
    32101 tactttaaag aaggcatatt tagtaagata aataactgtc tatatgagct taatagaagt
    32161 ttaaagataa agtttattaa attagaaaaa gaaaaagaaa gtgtaaaatc attagtaaca
    32221 gatatttccc atcaattaaa aactccttta gcatccttaa aattatacaa tacattactt
    32281 atagaagaag aattagaaga agatgaagcc aacgagttct tattaaccaa taaggcttct
    32341 ataaataaat tagaaaattt aataaattct ttagtgaaca tatcaaggtt agaaattagc
    32401 atgataaaca taaaaaaaga agataatgat ataaaaaata ctattctaaa tgcagtaaaa
    32461 agtgttaccc ctaaggctaa gagcaaaagt ataacattaa atttaaatga atttaacagt
    32521 agaattatac cacatgataa aaagtggact gaggagagta tttttaatgt attagacaat
    32581 gctgtaaagt atacacaggt aaatggagaa ataaatatat ctgtagaaga aactgctaat
    32641 ttctttaaaa ttataataga ggataatggc atagggattg aaaaaagtga gtttaataat
    32701 atatttaaac gtttttatag aggttctgct gatgaaattg aatctgtaga aggtagtggg
    32761 gtaggattgt atttaagtag aaagatttta gaagaacaag gtggaaatat tatagtttct
    32821 tcaaaagtag gaatagggag caagttttct ttgtttctta caactatgta atattaaatg
    32881 aaaggaaaat gtaagcctct acatttatta tataagtata aacagctcca gaaataaaaa
    32941 attaataaaa tatggagtaa tataacttag aatgagagga taattttatg aaaatactat
    33001 atactgaaaa tttatcaaag cattatggaa aaggagaaag cttagtaaga gctttggaca
    33061 atgttgactt agaaataaat gaaggtgaat ttgttgcaat aataggaaaa tcaggttctg
    33121 gaaaaagtac acttttgcat atgattggag gtcttgatat acctacatct gggaaggtgt
    33181 atatagataa taaaaatata tttacattaa aagaagaaga acttgctgta tttagaagaa
    33241 gaaaaatagg gtttatattt caaagctata atttaattcc atctcttaat gtatgggaaa
    33301 atgtagtgtt gccaatcggt ttagatggta gagaggtaga tgaacctttt ataaaagagc
    33361 ttttaaaatc attaggactt gaaaataaac acgacgtttt accaaataca ttatcaggtg
    33421 gtcaacaaca aagggtggca atagcaagag cattagctac aagaccagct ataatacttg
    33481 ctgatgaacc aactggaaac ctagattcta aaacatctga tgaggttatg agtatattaa
    33541 aatctatgtc taagaagtac agtcaaactc tagttatgat aactcatgat gacagtatag
    33601 cccaaatggc tgatagagtt atattcatag aagatggcag ggtgtcaaag gttggtgata
    33661 aaaatgatta atactactaa aatagcaaaa agtaatttaa agcaaaataa atcaaaaagt
    33721 attctaataa taattactat aatactttca accttaatgc tttcttctat tggaatttat
    33781 attgttgatg caggagcata tcaaaaagaa aatactataa agtattcagg taattatcaa
    33841 ggtatattag caaatgtaga cgaaaaacaa gctgatatat tgagtaatca tgcagatgtt
    33901 gaattaactg gtaaaatgaa tggagtaggt gttgaaaaac tggaagatga ttcaaatatt
    33961 tctctagcat acatgaatga agatgctttg aaattaaata gttttgaatt tatcaaagga
    34021 aaattgccat caaaagagaa tgaaattgtg ttagatagtg gagctttaaa ggcacttggt
    34081 tataaaaata aagatttagg tgaaaagata aaaatatctt ataatgacta taaaagtgat
    34141 aaaaaaattg aaaaagagtt cattataagt ggaatcttaa aaactagcga aatatctgaa
    34201 gcaggtaaat attattatgc tattatatca gaatcatata tgagaaatac tagagatatg
    34261 tcacaagaag attttaatat atatgtgaaa ttaaatgata aaagtaattt atcgatagaa
    34321 caagcaaaat caaaattaaa taagattgct aatgatgtag gattggacac tattaatgta
    34381 gctgtaaatg aaaactatat aaatgcttta aaaccagata tggaaacaat tatgggtgga
    34441 gtatttgtag ggttagtaat tgtattgtct agtattttag taatatacaa tatattttat
    34501 atttcaatag ttacaaaggt tcaagaattt ggaaagctta gagcaattgg tgcaactaaa
    34561 aaacaagtaa aaaatatagt atttaaggaa gggttcatat tagccggaat agcaatacca
    34621 ataggaataa ttttaggcta tgtacttgca aatattataa taaaatcatt tatggatata
    34681 gatgtaaaat catcacgatt accagttata ttatcggttg tggtaataag ctttatatct
    34741 gttgttttat cacttttaaa accaatgaaa gtagcatcaa aagtatccat tgttgacgca
    34801 gtaagatata caggaaataa aataagtaat aagagtaaga gaaaaggata taaaaatata
    34861 aatctaaaga gattatcaca tgccaattta gaaagaaata aaaaacgtac ttacatgaca
    34921 ttggcatcac ttatacttag tggaactata tttataacag tatcaactgc cttagaaagt
    34981 tttgatgctg agaaaatggc aagagaacac tttccttatg atatagaagt tagactatct
    35041 ggttatgaaa tgaacagtga taaaaatcct aaagataatt tgaatatttt acaaatggat
    35101 aatcctctaa gtaaagattt ttttaatcaa ataaagaaca tggaaggaat taaaagaata
    35161 gaatctgcaa gaagtgtaaa aattggtatg gaggactatg atgttgaatt taagtatgac
    35221 cttttacaaa gtataaatga aaatgatgta aaatcattaa acaagaatat aatagatgga
    35281 aaaataaatc ttgaaagact tcaaactgga gatgaaatag taattactca tgttgataca
    35341 gcaaaagaaa tgggagtaaa agcaggagat aaaataagat taactttata tgatggagat
    35401 aaaaagataa aaaaagaatt taaagttcaa gcaatagcta tgggggttcc aagttttggt
    35461 atagggaagg attttattga tagaactttg aaatacgatt caactagtag cttgggaata
    35521 tatacagaag aaggaaagta tcaagaaatc aaagatagta tcaagaagat tgctaaaaat
    35581 aatggatttt tagagactga ttttatagat agtagaattg agtcaaataa ggctactatt
    35641 tcatttataa agataatggg atacacgcta acaggcataa taggtgtgat tggatttatg
    35701 aatcttgtca acacaatgat aactagcata gttactagaa aaaaagaact tggtatgctt
    35761 caagctattg gtcttactaa taaacaatta gtgaaaatgc ttaattcaga ggcaatgtat
    35821 tacacttctg gaatgatgat aggaagtatt ctatttggag gtatattagg gtatattgct
    35881 gttatatttc taaaaaagac tggattatct tatgcaacat attctttgcc aatagtacca
    35941 atcttgttga tgattgtgtg tattcttata gctcaattta taacaactta tttgatagga
    36001 cgaagtttta ataaagaatc tcttattgat agagtaagat acagtgaata aaatacaaat
    36061 atttatggtt agtttaacta gcaaaaaaca tataaaaaaa tatagttaaa gagattcata
    36121 attaaatagg ttaaagcata gtacagagca aacaatttaa gcagatgttt gctctgtatt
    36181 ttattatgta atcaataata tatctaatat actgatatta ttcatgttag aaaatgtacc
    36241 ggtacaattc taaaaaagta taaaattgta ccatataaaa tgaaaatttt gtataataat
    36301 cgtatagaaa ataaatagga gctgatatat atgaataaga agattaatta tgcaccagga
    36361 ccaactgaaa ctagggaaaa tgtaagatta gcaagagcag aaaaaacaac aaatccagat
    36421 atagatattg attttgttga attttataaa aagacatgcg agaagtttgg taatataatt
    36481 ggaacaaaaa acgatgttta catattgagt ggtgaaggaa tattaggtct tgaagcagca
    36541 tgtgcatcac ttacagaaaa aggagataga gtacttgtaa ttgacaatgg tatatatgga
    36601 gaaggtttta aagattttgt aacaatgtat ggtggggagt atgtgctttt ttcaagtgaa
    36661 tatactaaaa gtatagatat tgatgaattg aaagcatttt tagatgagga tagtaatttt
    36721 aaatatgcaa cagtagtgca ttgtgatact ccaactggcg tattaaatga tgtaagcaaa
    36781 atatgtccat tacttaaaga atatggaata ttaactgtag ttgattctgt agcaggtatg
    36841 gtaggagaaa gattaagtgt agatgaatct aaaatagata taatattagg tggttcacaa
    36901 aaagctattt ctgcaccagc aggacttact atagtcggaa taagtcaaga tgcaaaaaat
    36961 tgtataaaaa atagaaaaac tgatgtaata ggtttttatt gtaatttaaa tatatgggaa
    37021 ggctattatg aaaaaaaata cttcccttat acaatgccaa taagtgacat aatggggctt
    37081 gataaagcac ttgataatat attagaagaa ggaatagaaa atgtattaaa tagacatgaa
    37141 aagatagctt atagtgttag aaaatctatt gaggaatatg gtctagaact atttttagaa
    37201 gaaggatatt ctaatacagt cacagctata aaaattcctg aaagtatagg agctttagaa
    37261 cttactgatt atatgcttaa aaattataat acacttgttg caacatcact aaatcaatat
    37321 atggatacta ttttaagaat aggtcatatg ggagagaatg caaatctaaa taaaatagaa
    37381 catgtactaa atgttttgga taaaagttta agtgcattag gattcaaagg aaatggaaat
    37441 ttgttaaatt tatttaataa gtattatttt taatagatag ggggatatag tatggaagtt
    37501 acagctaagc aaaaatttac aacgaaagac atggtggaaa cctcactatt aatagcatta
    37561 gtatttattg caactaaatt tataaacata agattaccaa tatctataaa tggtgggctt
    37621 gtgcatttag gaactgcaat gttgttcata tcagcaatag tatttggaag taaaaaaggt
    37681 gctttatcag gagctattgg tatgtcactt tttgatttga tatctgggtg gactttatgg
    37741 gcaccgttta cctttatagt tagaggagtt atgggttatt tacttggaaa gattgcatgg
    37801 gcaaatggta ataatgggaa taatttttta atcaatgtaa taggaatatg tgtttcatca
    37861 atttggatgc tatttggata ttatgtaaca gaagttatac tttatggtaa ttttatagta
    37921 cctcttactt caataccagg taatttaatg caagtattga taggtcttat aatagcgctt
    37981 cctatttcta aggtattgaa aaaatgtata aaataaatat aaagtgaact aaaatttatg
    38041 atagcataaa ttatactgta taatattagg atggagtaca taattaaaaa attttagtat
    38101 agaggttagt tcacaatgtt atcagttaca agatattcaa tcaaaaatgt tcgtttaaag
    38161 ccgtgggtaa agtttatttg gtattttgag acaaaatcaa atatactgtt aaataataag
    38221 ttacttccga cagacagtat agatattatt ctcaatcttt ctgatgttat ggaatataaa
    38281 attgaaaatc aagactatat tgctagtaat attcatttta atggaataag ggataaacat
    38341 ggatttatta ttcaacatgg aaatatacgt gttataggga tttcttttta tccatttggt
    38401 ctctatccat ttttaaagat accaatttca gagtttaaca gacaaattgt tgacctagaa
    38461 gcagtatcaa aactatttgc aaaaaaatta gaagagtcat taaatccaac aaaagcaata
    38521 gaaaaagttg ttttatgttt agaagaagta ttattatcca tattagaaga agatttaatt
    38581 tcaaataaat atgtaaagct tctaaattca tttatatatg ttaatagata tagcaatata
    38641 aaagcatttt gtgatgatac aaatataaat attaaaacat tggaaagaat ctgtttaaaa
    38701 tatacagggt atacacctaa gattttaaag agaatttaca gatttaaaat ggcaagcaat
    38761 caacttattt ataattataa agatgatgaa ctttttgatt ttatttatga aaatgagtac
    38821 tatgaccaag cacactttat aaaagaattt aaaaaatttt cagggacgtc accaattaaa
    38881 tttagtggtg agaataagac gattaaagaa aatataaagt acagctattt ataattatac
    38941 tgtcgatttt ttacaatacc tccaatttat tttttgatat gatataggaa aataaattgg
    39001 aggttttaca tatgaaaatt attacagaaa tagttgagtt taatgtggaa gaaaatttat
    39061 caaaagaaga gtttatagaa attgtaaatg acttagaatt aaaatttcat tctattcaat
    39121 ctggttttat tgatactgag cttttatatg atgaaaagtc tcaaaagtgg attatgatac
    39181 aacattggga atctatagaa gacctcaaga gtgtttctag taaaatgttt aaagattctt
    39241 caactgagaa atttagaaaa gctttaaaga atcaaactgt taagatgaat ataataccac
    39301 aaattaaaag ttggaaatta tagaactgaa tgtaaaagat agttaaatag tatcaaacta
    39361 aattagccaa ataacatttt gtatttaaat tgttatttgg cttttagtgt ttattttaat
    39421 atgagtgtta tatactagaa aaaccaacaa actgttagag tgtggattat cataatgtca
    39481 tattcgggag ctaaaaggct taatactgat ttgccaattg gtcaatccat gcatgtccat
    39541 ctggatatgc tgttattaaa gcatttacaa gccaatccct ttgctcttgt gataatagtg
    39601 ggactgttac atcgaagtct ttttgataac caagcctatc tatgtatatt gatttgcaaa
    39661 acaaaaccac ttcgggagcc atatatggga tattatctga tgttatcagt ctggccttat
    39721 ccatatctct tataattctt tgattttggg aaaaaagaaa ttttccatct ttctgtggat
    39781 tatatatcaa ttcaataaaa tcgaactgta actgttcgtc acactgtata ttcattttat
    39841 agttatcatc ctcgactttt tttaattcaa taaatgagca atcaggctta atcgcaaaaa
    39901 cacaaatttg ctctatatgt tgcttgttaa ggtcgataat aggtcgtaat aaataattac
    39961 ccaagggctc atatatatcc catccttgat taagcatata ctgaatgctc ttttctttat
    40021 ctgtgtcaga aatccatatg tcaatatcac tgtgtgggcg aatatgcata ttcgcaaata
    40081 attctagggc atatccacca catattgaat atgaaaagcc acaatcatta aaaaagttta
    40141 cacaatcttt aattagtttg ttcatagcaa cctccttttg catgtactga aataaattaa
    40201 attttttaaa ataccaacta aatgtttgtt ttgtgtaaat ataaaactgc cgatattaag
    40261 gcagttttat atttactatt tagaaaattt attaacaaat ttttgatatt cacacattat
    40321 cttatcattc ataaaagaaa tacccataaa agcagcttgc tcaccaaaca aagtaaaacg
    40381 ttctatcatc tgttgtggat tacctggata aactgttgga atacaccatg tgtttagaag
    40441 aaaaccaaac atttgagcag caatctctgg atttttaact tccatagaat tatcttgatt
    40501 tccttcttca atcaatgctt ttatccaagg cacaatatca tttataatct catcaaactg
    40561 cgtagctaaa tacttaggat tacgcaatag tgatgatgac attaaaaaaa tgtcttgttt
    40621 attgtgctgt tcataagtat gaagcaacct atattgtaat ttttctaatg cggtctttcc
    40681 ttcatcattt tttacctcat acccataaaa tccatcatta tacaaccgac ttgtgattgc
    40741 cttaattatt tcgtcttttg atttaaagtg atgataaata gcacctcttg aaaggccatc
    40801 taaattatct acaatgtctt gaatcgttgt ctgctcatac cctttttcta agaataactt
    40861 atgtgaaata tcaagtattt tttgtatagt attatcaggt tctttttttc ttcccaaaaa
    40921 actcactcct cgaaacaatc atttggtatg tttatcttag caaatacata atgatttgtc
    40981 aatgtgtctt tttagcatgt tgaacaggta tattgccatg ctttcattat tttatttttt
    41041 tgccttatac tggactatat ttgcagtttc ctaatatatt tggctcatat ttaaatacca
    41101 ttatctaaaa gcactattgc tgtacgagag gcaataggca ttttagaaga aggaggagtt
    41161 gagctaaagt atacatcata atctcttaag ttttcttttt ttgtgtttcc tccaaactct
    41221 accatatcag tatttaatat cgttttgtag tttgtatttt gaaactttga aatatcaact
    41281 gattgtatta gattagggtg gaaattaaat ataaataaat atttgccctt actgtacacc
    41341 aaaatctttt tatcattatc catatgtata agttcatgac tattttggat aaaaatatca
    41401 ctgtattttg taagttcgag catagattta tcaaaattta ataattgttt atactttaag
    41461 ttgttatctt ctgaaaggct ccattgtctt ctggcatact tatagctcca attgttgcct
    41521 tctcgtggaa aatcaatcca ctcaggatgt ccaaattcat ttcccataaa atttagatat
    41581 ccttcacctg ctagagaaaa agttattaat ttaattaatt taataagaga tattgctcta
    41641 ttgataacat ggttatttga gtttatttcc atattccagt acatttcctt gtcagctagc
    41701 caaaaaataa ttgttttatc gccaactaat gcttggtcat gggattcaca atatcctata
    41761 tttttttctc caggtcgtct agtagtaagt tcataccaca ttttgcccaa atcccagtct
    41821 tcatcagata agttagagat agtttttatc caaaaatcag gtactcccat tgcgagtcta
    41881 tagtcaaatc caattccgcc gtcttttata gggatacaca taccaggcat tccactcata
    41941 tcttctgcaa tacttatcga attaggttta atttctttca ttaattcatt tgcaaattgg
    42001 agatatgtta tagcttcaat atctgtattc atactaaaat atttttcata actatcaaat
    42061 gaaactccaa gaccatggtt atgatataac attgaagtta caccatcaaa cctaaagcca
    42121 tcaaaatggt actcatttaa ccaaaatttt atatttgaaa gcaaaaaatg tattacttca
    42181 ggtttaccat agttaaaaag ttttgtaccc caagcaggat gatttccctt tgaacctgag
    42241 tggaaaaatt gatgttcact tccatcaaac tcatttattc cttctaaagt attctttaca
    42301 gcatgagaat gaactaaatc taataaaaca gcaatcccca ttgaatgagc agtgtttatg
    42361 aggtttttta agtcttcagg agtaccaaac ctagatgaga ttgcataaaa gtttgaaact
    42421 tggtatccaa aagatgcata atatggatgt tccataatag ccataagctg aatggtattg
    42481 tatccagctt tttttatctt aggaagtatt ttttcagtaa attcattata agttccaata
    42541 gattcgcttt cagtagacat acctatatga cattcataga ttagtggaga agttatgttt
    42601 tttaagtcaa aatcattgtc agtccagata aatggagttt ttggttgcca tatttgtcca
    42661 ttaaatccac caaaatcttt ttgaattact ctttttatat ataatggtat acggtcaaat
    42721 gtttttccat ttgcagtaac ttgtaccttt acctctgatt tgtgaggtaa gctattttga
    42781 ccaggaataa atatttccca attaccagac ccaatttttc ttagaggatg agattttcta
    42841 ttccaattat taaagtcacc aattagtgac aaactatctg catttggagc ccattcccta
    42901 tagaagaatc catcatttgt ctgatgaaat ccatagtaaa gatgagcatt tgcaaaagaa
    42961 ctaaaatctt tatagttttt caatgttttt gatttcatat cctcataatg tttcattcgc
    43021 ttttttatat cagattcaaa tggttgtagg tatacatcaa tatctaaaat tttaaatctt
    43081 ttttgacttt tcattgtatt tctcctccat aataaatatt acatctaaaa aataatattt
    43141 atctcatact atcttctctg tataattgat atatattata taatcctaat aaaaagctta
    43201 agccaccaat gattaatttc ataatttacc tccctagtat ttatacttat atatcgtatt
    43261 catcaaaatt taaaagtttg tttaaaactc ttttaataat atcataatca aagcctttat
    43321 aggaaagatg ttgagaaatt ttttgatata ttttcttttt atcttctttc tttactcttt
    43381 catacctttt ttttgctaga tacatagcat tttcaaattc agtgtccttg tctaattcag
    43441 atactgcttc attgattgta cttctattga tacctttatt atataaattc tgcttaattc
    43501 tgtttttgcc acatttattt aggttaacat ttgtgttaac aattttttga gctaatacac
    43561 tgtcatttac gagattataa cttttaagaa aatctatgac cctctcaatt atattttcat
    43621 caaattctga tgatagtttt tcttttaatt ttttttcaga ttggtcagca tgagataaaa
    43681 tatttaatgc tttattttta gcttttatat acatttcatc atctaaaata ggttttaatt
    43741 cttcttcatt tatttcattc ccttttttta aattaaatgt ataaaccagt tctttaaata
    43801 tagcaataaa aaatttatca tctacataaa tattaactct atcatcattt cttttttgtt
    43861 gttctatttt tgtaattata cccataagtc ctcctttttt atatgtaatt atattaacaa
    43921 aagcaactaa taaaatttaa caaaaaactt atatttgtat gttatatttt atcaaaatta
    43981 agacaaaata gtaaaaagtt atttttatta aaaagtaaag cagaattatg ttaaataatt
    44041 attttttaaa gtgtttttta gcatataaat ataattatat acccaaaaaa acaaattata
    44101 agctttaaga aataaaaaat aatggtacaa tagtattata acattaaaag gagacaaaat
    44161 atgagaagtg aaaatctagt taagatggca gagttgaaaa atactgaaaa actagagaaa
    44221 tttaatcgcc ataaaggcaa aatcaaaata ggtatattgg gaggtacttt tgaccctata
    44281 cactatgctc atttagcaac agcagaattt attagagaca agtatgacat tgacaaaata
    44341 atctttatac catcaggaaa tccaccacat aaattatgta tcactacaga taagtatgat
    44401 agatataata tgacacttct agcaactgaa agcaacgaag attttttagt ttcaaaagta
    44461 gaaatcgaaa gaaagaaaag gacttataca atagatacat taaaatactt aaagaaaaaa
    44521 tacaaaaatg cagacattta ttttataaca ggtgcagatg caatttgtag tgttgaagag
    44581 tggaaagatg taaagaaaaa ctttgagtta gctactttta tagccgcaac tagaccagga
    44641 attagtttgt taaggtcaca agagactata gaaaaactaa ctaagaagta taatgctgac
    44701 attataacag tttatgttcc atcactggat atatcgtcca catatataag ggaacagcta
    44761 aatgaaggca agtcaatacg ttacttagta cccgaaaatg tagaaaatta tttatatgaa
    44821 aataaactat atcaatatgg agatgattaa atgaacttag aaaatattaa ccaaagacta
    44881 aatcaaatgc taccagtggg gaggcttagc cattcaaaaa atgttgcaaa atgtgctgaa
    44941 aaattatgtg agatttatgg atgtgacaaa gaaaaagctt acttagcagg aatgattcat
    45001 gattgtgcaa agtatttaag tgacaaggaa atagaggatt atgtaaataa gtatgaaata
    45061 tatttagacc caatagagga tggaaatcgt tccttgtctc atagtgtaat tggggcgtac
    45121 atatgcgagt atgaatttga agtggaagat gaagatatta taaatgcaat caaatatcat
    45181 acaacaggga gagaggacat gtctctttta gaaaaaataa tttacatagc tgatttaatt
    45241 gaagaaggaa gaaaattccc agttgtagat acattaagag aattagcata tggagggaag
    45301 cttgatgaag cacttttaac ttcttttaat aatactttaa tgtttgtcat caataaaaaa
    45361 gaagagatac atccaagaac agttatggca agaaactatc taattaaaga aaagttatta
    45421 taaaaaagct atataaaggc aaacatatta ataaatttaa atttgactat gttacaaaat
    45481 cgtattaata tgttacaata actaagtgta ttttaattag gaaagtgagg aatttttata
    45541 tgacagtgga acaaatgaca aaaatagcat atgatgccat agaagataaa ctgggtcaag
    45601 atacagttat aataaatata ggaaaagttt ctagtttgtg tgattatttt attattacta
    45661 cagcatcttc tcagagacag gtaaaagcta ttgctgacaa tgtggaagat gaattagcaa
    45721 aactaggatt agagccaaga ggtaaagaag gacaaggaac tcaaacttgg gtactccttg
    45781 attatggaga cataatggtt catgtattta atgaggaaaa tagagggttt tataatttag
    45841 aaaaattatg gaaagatgca ccttatatag atattgacac attagcataa acatgataat
    45901 atatgttatt ataattagaa aatttcaaaa attatattaa attgaataga ctagagcagt
    45961 aaaagattat attttttcag agagttagtg gaaggtgaga actaatatta tataactttg
    46021 aacttactag attaaaatct attctccatg gctggattaa aagctatcta agagagtcta
    46081 tatatgtagt aggctaatta gggtggtacc gcgaagattt atcctcgtcc ctaaacgtaa
    46141 gtttagtgac gaggattttt tattttcaaa gaattatttg gaaattataa gtaaataata
    46201 ctaaataagg tagttataca caattaaaaa taggaggcaa aatatgagcg tatataattt
    46261 taaagaagta gaatcgaaat ggcaaaaaat ctggaaagat aataatcagt ataaaatgga
    46321 tactgcacaa actgaaaaac ctaattatta cacattagaa atgttccctt atccatctgg
    46381 aaaaatacac atgggacatg ttagaaatta ttctataggt gatgttgtcg caagattcaa
    46441 aaaaatggaa ggatataatg tacttcatcc aatgggatgg gattcttttg gattaccagc
    46501 tgaaaatgca gctataaaac atggaataca tccacataaa tggacaatgg aaaatataga
    46561 agaaatgaaa gagcaattaa atttattagg tattagttat gattgggata aagaagttgc
    46621 aacttcaacg ccagaatact atagatttac acaagaaata tttttgaagt ttttagagca
    46681 tgggcttgca tataagaaaa aatcatatgt taactggtgt ccttcttgtg agactgttct
    46741 tgcaaatgag caagttgttc aaggagcatg tgagagatgt aaagcaacag tattaaagaa
    46801 agatttagaa caatggtatt ttaagactac tgaatttgca gaagaattac ttaatgactt
    46861 agatatatta gatggatggc cagaaaaagt taaaacaatg caaaaaaatt ggataggtaa
    46921 aagtacagga gcagatttag tttttgatat agatggaact gataaatcta tgacagtatt
    46981 tacaactaga ccagacacaa cttatggagt tacttatatg gtacttgctc cagagcatga
    47041 attagttaaa gaattggttg cagggactga atatgaagca gatgttgaag cttttgttca
    47101 aaaaatgcat actatgacag aaatagaaag aacagcagct gatgtagaaa aagaaggaat
    47161 gtttataggt agatatgtta taaatccttt aaatggcaag aaagttcctc tatggatagc
    47221 taactatgta ttagttgagt atggaacagg tgctataatg gcagttccag cacatgatga
    47281 aagagataga gattttgctg aaaaatataa tttagacata attgatgtaa taacagaaga
    47341 taacaaaatg ataaattcag aagaatttaa tggattagat gcttcagaag gatttgaagg
    47401 aataatcgat aagttagaaa aagaaggtag aggaaagaga acaattaatt atagacttag
    47461 agactggtta gtttcaagac aaagatactg gggttgtcct atacctgtgg tttattgtga
    47521 tgaatgtgga atagttccag ttaaaaagga agatttacca gttcttttac caacagatgt
    47581 tgaatttact ggaaaagggg aatctccact tacgacttca aagcaattta tgtcaacaac
    47641 ttgtcctcac tgtggaaaac cagctagaag ggaagttgat actatggata cattcgttga
    47701 ttcttcttgg tatttcttaa gatatgtgga tagcaataat gaaaatgaac catttagtaa
    47761 ggaattagtt aatagatggc atccagtaga ccaatatata ggtggagtag aacatgctat
    47821 aatgcattta ctttatgcaa gatggtttgt aaaggcattt aagagtatgg gaatggtaga
    47881 cttcaatgag ccatttaaaa acttacttac tcaaggaatg gtacttatgg atggttctaa
    47941 aatgagtaag tctaaaggga atacagtatc tcctatggat ataatagatg agtatggagc
    48001 agatactgca agacttttcg tattatttgc agcaccacca gaaagagatt tggactggtc
    48061 agagcaaggt gttgatggat gctttagatt cttaaatagg gtttatagat tggttgacga
    48121 gttagcagat gtggttaaaa aggatgtaga gtttggagaa ttaaattccc aagataagga
    48181 tatgagatat actatacact ctacacttaa aaaagttact gctgatttaa gtgaaaaatt
    48241 cggatttaat actgctatat cagctcttat ggaattaata aatgatatgt ataaatataa
    48301 agagttagat aatataaacg aagcagttat aaaagaaggt gtacaaacta tagtaactat
    48361 aattgcacca tttgcccctc atttaggtga agaactatgg actatgatag gtaaagaagg
    48421 aagtgtattt gacatagact ggcctaaata tgacgaaaaa gctttagtaa aagatgaaat
    48481 agaagttgtt gtacaagtta atggaaaagt tagaggaaaa ttaactgtta actcaaatat
    48541 atctaaagat gagatggaaa aggtagcttt agaagatgaa aaaataaaag gattagttga
    48601 aggtaaaact atagttaaag ttgtagctgt acctaaaaaa ctagtaaata tagttgttaa
    48661 ataactcaaa aatatgaaca aaaatataaa tttataaaat aaacgaggct gtctcaaaat
    48721 agagataagc cttttttcat tgttgaaatt ataaaattgt tgaaattata aaaatagatt
    48781 tgattttata caaaaaaatg attaaagaac taaaaagttc attcttatat accctagttg
    48841 ttgttttaaa tattattata attaatgtta aatcgagtta atgtattaag tggtatgtaa
    48901 atcattcagt ttccaaagtg ttgttcatca aggaactgct ctaagcttaa acgaaaaaaa
    48961 tataattatt gtattttgaa atttttttct atataatgaa aacaggcaaa aaaggtgcgt
    49021 atctatgctt tatatgaaac acccagacaa cgaaattcag attcatataa tagctaccat
    49081 gtttctaaaa aggaacttgt aaaaaagata gcgtttcaac ttcccagttg attaaaatta
    49141 tcagcaggaa aacaagtatg gtcagcagtg gtattctaat gggtgttgtc gatatatcca
    49201 agttgggatt gtctgaggat gttatcaaat aacttgtgat aggtgcagta gatgtggaga
    49261 ttcctgatac ggatttattc tcaggggatg gttgcttcgg gagatatgga gcgtaaccag
    49321 tttattgata tggtaaccat tttttgtcta atttgatgaa agaatcccaa gaataccata
    49381 cagaagtaag acaggaatta actggtggta taaactgata aaggcaaatt taaaaatttt
    49441 gataggatga ttttaagatt tatcttctat tttgtgtttt agaaataatt gaaatgttat
    49501 gaggaggtat gtacaaatgg agactgtaac aaataatcaa tcaggtgtag aaattcaact
    49561 cagtctgttt gaagctatca aagatttatt gttaattaat cctattttct tgttgggaat
    49621 tatcttgatt ggtattttct tagttgtaat attcaagaaa aatagtgata ttccaaaggt
    49681 aaaaacatct attttatcac tggcaatgta ttactactta tgtttaacac tatcgcatat
    49741 tgttggtatc cctacattca gtgaatatat aagactgtca cagttagggg aaacgttctt
    49801 taatccaaac ataaatctta ttccttttag tgatggattt agtttgagtt ttattttgaa
    49861 tattttactt tttgtcccat taggtttttt atgtccgctt atcagcaaaa cctttgaacg
    49921 tttgagaaat acattcttga ttggttttgg attatctctt tttatcgaaa ctattcagct
    49981 ttttacgtta cacagagcaa ccgatataga cgacttactc acgaatgtaa ttggaacaat
    50041 aataggctat ttctgcttca aactgattgc taaattgcga attgtaaaac tacattcaga
    50101 tgatgactct atggaacagg attacacagt atgtattccg attgccatta taatagttgc
    50161 ccttatatta ggatttttta gttaagttcc aaatagctaa tttgggaatt atggaggtca
    50221 ttaagtgaat aaaattactt ttatatgttt aggtgtaaaa agtatggaga agtcaattaa
    50281 attttataga gatggattag gattttagat tacaaacttt tagtttacca aggagatagc
    50341 aaagttgtgt gccaaagggt aaccatttgg aaatccagac aacataacag atagtacgtt
    50401 accttttaca ggagcatact atctgttata ttgtcaacat cctattttat ggtttgtgtg
    50461 tagtttcctg taaactgaac taaataatta aatagaagct attagaatta ataataacag
    50521 atagatatta ataagcataa acaaatagta aaatgtgtag atatagacgt ttttaagtga
    50581 aactattata aaataattga ctgataatca actgacaaaa cctatttttt taggtttaac
    50641 tgacatttaa ctgacagtca gtttttacta tttaaataga agttcgctta gattgtcgga
    50701 agcttctttg tccatttctt taagtacatg agaatatcta ttcatagtta tttttatatc
    50761 tgtatgaccc aatctttcag aaacaacttt catattagtt ccccctaaaa gcagcagagt
    50821 ggcacttgta tatcttaaat catgtattct aatctttttt aaattatttt ttttgtaaaa
    50881 ttgtgaaacg tttttcttag tgaagaaggt agaaacggat ttaaattggt gtttagacaa
    50941 actaaattat ttctgttttc caggatacct tacaatttta atttgctttg tcttagtttt
    51001 ttaattttca atttttcaat taattctttt ggagctgata aagctctttt tgattttggt
    51061 gtttttggct ctttaaaaga tattttgcca ttagaataga caagaatttg attaacattt
    51121 atcagattgt tatctaagtc aacatctgac cacctaagcc cagtagcttc tcccattctt
    51181 aaacctagaa gtaacattaa aagaataggt atttctatat tattactaag taacttttct
    51241 attagcaata atacttcttt tctattgtat atttcatttg tagaatattt ttctttagaa
    51301 ggaagtttta taaaatcaca tgaattttct tgtatttctc ttaatctata tgcttccctt
    51361 attacagaac ttagaaagct ataccttact ttagcactag taaaggtaga attattaaag
    51421 ttataattta caaaagcttg tactgaacta ggatttactt ctgtgagttt tagattctta
    51481 aaaagaggtt ctatgtaatt tttaacccaa gattttgtat ttgtaacagt atatggagac
    51541 caattatttt tattcatgtc catgtattta taacatcttt ctacaaatgt catatctttt
    51601 ggagcaacaa acttattatt gtttatagta gattttattt caattaaatg tttttcagca
    51661 tcctttttct tttcataact tccataactt ttctgtttta tcttgccagt tgtttcctct
    51721 atgtactcca catatacata gaatttttcc cctctttttc ttataaaagc tgatttgata
    51781 ttcatatatg tacgctccct ttataagtta gttttataaa agaacagttg tactactcta
    51841 attatgtcat tatcttttta attctttaca gttacattat aacacgtatt tgtatacact
    51901 taaattaaca ggaagataaa tatcgttaaa ggaggaaaag aaaatttaat gtagaattat
    51961 taagatatat agtatttcat atataaaagg gggagatatt gtgaaattaa agaaattatt
    52021 atcactaggg ttagtgtcaa tgtttgttgc tggttttcct atatcagcta atgcacttga
    52081 taaaattgat aaaattcaag gagcagataa atacgaaact gctggtatca tagctgacaa
    52141 acaaagttat actactgcaa tacttataaa tgcagatagt acaatggctg atgggctaag
    52201 tgcgagtgga cttgcaggag caacaaatgc accaatcctt ttgactaaaa agaataatat
    52261 acctaatgca actcttaaaa gagtagaaaa agctaaaaag gtatacataa taggaggaga
    52321 aagttccatt gataaagcaa cagaaacttt tctaaaagat aaaggaatag agactagaag
    52381 gcttcaaggt aatgatagga ttaagacaag ttataatgta gcaaaagaaa taaattccat
    52441 taataaagta aataaagtaa tattaactaa cgctttcaaa ggtgagccag atgctatgag
    52501 tgctgcacct gtagcagtta gagataaagc agctatagta ttaactgatg gaaaaagtgt
    52561 tccatttaat acaactggta tagaaagtta tgcaataggt ggcacttcat caatgagtga
    52621 tagtttagta aatgatacta attcaactcg attgggtgga gtagatagat atgatactaa
    52681 taaaaaaata gtaaataagt tctataatgg cgcaaaagaa ttttatatag ctagtggtac
    52741 tgatttagtt tatgctttag ttgcttcacc aatggctaaa aataatccta ttgtactagt
    52801 tgatattgga agtaataaag atatacttaa aaatgctgca aaagtaaccg ggataggaaa
    52861 tctaagtgat aaaattatgc tagagtgtga aaataccatc aataatatta gtcttccatc
    52921 ttcaaataaa aatataatat gtggattaaa gattgatttt gattcaaatc acataatttg
    52981 gcaagataaa ggaagttatc ttgaatgtta tgatgataac cttgaatatt atactgaaaa
    53041 atataaagac ccaacagttc ctataaatat agaaaataca agtacacaaa atttagatgt
    53101 aacaaaatta aaagtttatg gagaagctaa ttcaacatta tatatggggc aatacgctaa
    53161 aataaaaatg gattttaata gtttcggtgt attaaagcca ggagaaaaat gtactattta
    53221 tttagatata atttcattag atccatcaag aagcatgaca ttaacatttt cttatgtagg
    53281 tgataaagaa aattataaat atgaacaagg attggcaagt agaatattat tttataaccc
    53341 ggatggagaa gatttttttg aatataaata actagtgggt atgtaaatgt ctcgatattg
    53401 ctcatatgtt gagttattat atttagtttc atatgaacta tatggatttt aaaattaaaa
    53461 atacttaaaa acatttactt taatagtagg tgtttttttg attaaaagaa tattattata
    53521 atgtaaaaag taataaatag gtaaaatatg taagaattat atgttataat atttttagca
    53581 agaagatgta atctacaatt tatagagtgg agttcatgta tcaaaaaatt atcctcccga
    53641 cgttaagaag ggaggtgaat atacatggat aattttttac aaggcatact agcaagtcta
    53701 tctgctagct taatagttta tatagctagc aaactattta gaaagcgtaa aaaaccactc
    53761 aaagcggcaa ctaagagtgg ttgggaattt gatttaaaaa tcagattcca taaaactaag
    53821 taatttctaa attatgaact ccactctaca gcaaaataga ttgtagttct tcttgctttt
    53881 attatatcac aaattggtac agatattcaa aaataatatt tttatgatat aataaagtca
    53941 tagaaatttt gcagtgttcg attttttgaa gaaattaagg cttaacagtt gaaatataag
    54001 gcattgagga cttgtgataa gtgttatcaa ttgcactact catggttcac tgcaaatttg
    54061 agagatttgt atatgtgtag gcattggaaa tactcaattt attttggggt tttatattaa
    54121 ctatatggaa tgtaaatttc atattccatg cattctgctt acacttaata gaaaagtttt
    54181 atattaacta tatggaatgt aaattatttc tagcgacttg gtcggttgct ccatttagct
    54241 tgttttatat taactatatg gaatgtaaat tttttcaaat ctgatatatc gaccttaaat
    54301 ttcgtgggtt ttatattaac tatatggaat gtaaatgata taaactttgg gagttcagaa
    54361 gaaggattaa aaagttttat attaactata tggaatgtaa attagagatg aactcagata
    54421 gaaaaacatg tagatgtgtg ttttatatta actatatgga atgtaaattc ttcaacagtt
    54481 gtgttaccat ctcctacacg cacaggtttt atattaacta tatggaatgt aaattgctac
    54541 gtaaccagtt tcaccgcttt cagtatataa cgttttatat taactatatg gaatgtaaat
    54601 tgttggtata gtttcagaaa agaaattcga aacacttgtt ttatattaac tatatggaat
    54661 gtaaattgta tccaaaaaat tacaataatc atacgaactg ctaatataag cagtcaatat
    54721 atgtgtacat ttatctattt tatctctaaa tatataaatt attatccccc taaaaaactt
    54781 tcataaaaac aaaaagaaca atatctcttt ggcaactggc tgacataact cataagatat
    54841 ttatataagt cttagtctct atagctttgc gtcactagat ttctctagtt ttgccgattt
    54901 agttttattc tataactaaa taatacaata gaattagtta ttattcaata agattgtttg
    54961 aaaattgaat aaatttatag gtatgaacgt aatttcacac ttaaaaaaca gactaaatac
    55021 gtagaatata tagaaaaatt tacctgtagt ttttgtgata aaaagctcct attattaatt
    55081 taagctagat aagtttgagg aagtgacata aattgaaaga aggaatatat tatgttgaat
    55141 aaaaaattac cagatgcaga attaaaaatt atgaaataca tatagaatac tggttataaa
    55201 actgtaatat caaaagatgt tgcagatgaa atagaaaaaa catatgcttg gaagcataca
    55261 actacaatta cacttttagc tagattaact aaaaaaggtt ttttcatatc gcagagaatt
    55321 gggaaacatg tacactatag agtattaata aaagagaaag aatatctcaa aatagaggga
    55381 aaaagaattt ttggaggtct acataacaat ccattatcag aattaatttc aaaattgcat
    55441 gatggagaag aaataactga agaaaaaata atagaaatag gaaattggat aaaaagctgg
    55501 aaagatgaag attaataaat aaaaggtagc tactaatata agtgctacct tttttcttgt
    55561 ggataatatt ggggataagt tgtggaaaac ttgtggataa aatattttgc tgacatttaa
    55621 ctgacataag tattagattt tgatttaaaa atgttgaaat atcaataaat aattaaatag
    55681 aagttattag aattaacaat agattccttt ttcaaagaaa tctttgattt catcaaggtt
    55741 atcagttttt ccaagtgcta agataagttt tattctagct ttttgacctg gtaagtcccc
    55801 accaaatata caaccaagat tttttaaatc tctaccagaa ccaaagtaac cataactatc
    55861 gaatactcta cctgaatgac atctagaaac tataactaca ggaagtcctt tttctctagc
    55921 atattcaact ccagaaagca tttgaggagg aatattacct ctacccattg cctcaataac
    55981 tataccttta taaccactat caacagcaaa tcttataaag tcagcatttt ctcctacata
    56041 tgctttaaat aaggcaactt tagattctac cttatcagta tctataattg ttctatttac
    56101 aatatctctt gtaaggacaa gttcgttgca gtcaattatt cctaatgggc cactagttag
    56161 agatttaaat gtatttagag aaagagtatt tgttttagta gcttcagaag ctaataatac
    56221 ttcattgttt aaaactacaa ggactccttt tcccatagca tctttggata ctgcagtaca
    56281 aactgatgca gataaattac ttgaaccatc atatccaagt tcagaactac ttctcatagc
    56341 acctgtgact attacaggtt tgatgttgtc aattgtaagg tctagaaaat aagctgtttc
    56401 ctctaaacta tctgtaccat gtgttattac aacacctgta atatcttttc ttgctaataa
    56461 atcatttaca taatttttca attccatcat tctataaggt gttatgtgag gtcctggaat
    56521 ttcatcaaaa ttaaaaactt caacatctgc aactttatca atgttggtaa ccattgatag
    56581 tatttgttca cctgataaag ttggtatagc tgctccgact ttatcatcta ctgtcataga
    56641 tatagttcca ccagtaaaaa ctatggcaac ttttttctta atactcatac tattctctgc
    56701 ctttcataaa taaaatttat aattccgata ggattatatc aaaaaaagta gttaaggtct
    56761 acataaactc ttttattcat ataatttaga tatttcagtg taatataatt atttcttaat
    56821 tttttgccat tcaacgatat aaccatttaa tatctctctt atggcttttc ctatcttagt
    56881 ataagcttca tcatatagat ttgctagaga tattctaatt gaccattcag gaccatagaa
    56941 tccatttcca ctaagtaaaa ctactgaata gtcattagct aatttataaa gaacatctac
    57001 tggagatgca gttttactta taaatttaaa taagtcttct ccgtagttta atttagccca
    57061 ttcttcaata tcaaattgag tgtaatatgc agcattgttt ttgttttcat taattggaag
    57121 ctctaaagct tcaaataata gtttttgacg tctatggcag atactcatat tgagtttttt
    57181 gtaggcatct actttgtcaa tcaatgcaaa agcagagaaa aacgccattt gtacttgctg
    57241 tggagtagaa agaccagcag tatggttgag agcaacaagt ctgctatcag caacaactct
    57301 ttccataaat gaaaggctag aagggttaag actcatatca ctgtaacgct tatctactga
    57361 tttttttaat tctccagtta aatcatttat tttcttatca aaaacatttt tcttatgaag
    57421 ggcaaatgta ccaagtctcc atcctgtaac tccaaaatat tttgaataag aatatactcc
    57481 aacagtgttg taaggtagtt ttgacattaa ggatgaaaaa tcttctacaa aagttccata
    57541 tacatcatct gatattatca ttaaatcttt attataattt tcaattacat ctattagatt
    57601 attacaagat gtttcatcca tagctataga agcaggatta ttaggattaa caacgaataa
    57661 agctttaata gatttgtcac gaagtttctc taattctttt tttgtatatt gccatgtatg
    57721 agcacctttt tcatcaactt cattagcatt tatatttacc actttaaagt cgtaacgagg
    57781 aaggttaggt atttcaagat aaggtgtaaa tattggagtc attaaggcta tggtatctcc
    57841 tttttttaga agttcatttg ccattaatga atcaaatata tagcacatag cagctgtagc
    57901 accttcaaca gcaaaaattt ctacatcacc atatttacct gatatatcat atttcatttc
    57961 ttgaactagg taatcgtgta ctattttttc catatgaggt aacattctat ctggaagtgg
    58021 atagttatca ccaataattc catcagctag ttcatgaaca aattcatctc catcaaatcc
    58081 aagttcattt ataccaaagt ttataatatc tctagctaaa tatgctccag gcatatctat
    58141 attttcattt ataaatttaa aaaatctttc tttaataccc tttttttgag gcattccagc
    58201 caaatgacct aaatcccaat tagaacgagt ttcagtaata gcgaaatgac caaaagtaaa
    58261 aaaggcttct ctagcagttg aacaagtcca gtttggattt ccacgacctg catcaagtaa
    58321 ttctctgtta ttttcttttg cagtgtattt tgcaatatct attaatttgt ccttaaattc
    58381 aaaagggctt atttttccat atatgttttt gatttcttta taagtatgat ttttcatgtt
    58441 aaattcctcc ttatgtaata agtttcacat ttttataata aaataaacaa gttgcaaaaa
    58501 tgattatact ttaattataa taggtttata gaaaaagtaa agtatgaaat taa
//
LOCUS       DAMJWC010000018        56750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMJWC010000018 DAMJWC010000000
VERSION     DAMJWC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.018"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            202..1419
                     /locus_tag="PC503_001301"
     CDS             202..1419
                     /locus_tag="PC503_001301"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF2527307.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1514..1894
                     /locus_tag="PC503_001302"
     CDS             1514..1894
                     /locus_tag="PC503_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2527308.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2178..2660
                     /locus_tag="PC503_001303"
     CDS             2178..2660
                     /locus_tag="PC503_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2527309.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2681..3496
                     /locus_tag="PC503_001304"
     CDS             2681..3496
                     /locus_tag="PC503_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2527310.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3547..5097
                     /locus_tag="PC503_001305"
     CDS             3547..5097
                     /locus_tag="PC503_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2527311.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPFLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5194..6546
                     /locus_tag="PC503_001306"
     CDS             5194..6546
                     /locus_tag="PC503_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2527312.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6677..7435
                     /locus_tag="PC503_001307"
     CDS             6677..7435
                     /locus_tag="PC503_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527313.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7482..8201
                     /locus_tag="PC503_001308"
     CDS             7482..8201
                     /locus_tag="PC503_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2527314.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8325..9725)
                     /locus_tag="PC503_001309"
     CDS             complement(8325..9725)
                     /locus_tag="PC503_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF2527315.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9729..10637)
                     /locus_tag="PC503_001310"
     CDS             complement(9729..10637)
                     /locus_tag="PC503_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2527316.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10898..11545
                     /locus_tag="PC503_001311"
     CDS             10898..11545
                     /locus_tag="PC503_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2527317.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11870..14509
                     /locus_tag="PC503_001312"
     CDS             11870..14509
                     /locus_tag="PC503_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2527318.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHIEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMNTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14567..15670)
                     /locus_tag="PC503_001313"
     CDS             complement(14567..15670)
                     /locus_tag="PC503_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF2527319.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVREAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16030..16851
                     /locus_tag="PC503_001314"
     CDS             16030..16851
                     /locus_tag="PC503_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2527320.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16930..17141
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17228..18544
                     /gene="argH"
                     /locus_tag="PC503_001315"
     CDS             17228..18544
                     /gene="argH"
                     /locus_tag="PC503_001315"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF2527321.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18793..19131
                     /locus_tag="PC503_001316"
     CDS             18793..19131
                     /locus_tag="PC503_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF2527322.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19258..20547)
                     /locus_tag="PC503_001317"
     CDS             complement(19258..20547)
                     /locus_tag="PC503_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2527323.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20627..21331
                     /locus_tag="PC503_001318"
     CDS             20627..21331
                     /locus_tag="PC503_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDF2527324.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21423..22469
                     /gene="selD"
                     /locus_tag="PC503_001319"
     CDS             21423..22469
                     /gene="selD"
                     /locus_tag="PC503_001319"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21471..21473,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF2527325.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22487..23899
                     /locus_tag="PC503_001320"
     CDS             22487..23899
                     /locus_tag="PC503_001320"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF2527326.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24013..25896
                     /gene="selB"
                     /locus_tag="PC503_001321"
     CDS             24013..25896
                     /gene="selB"
                     /locus_tag="PC503_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF2527327.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26001..28739
                     /locus_tag="PC503_001322"
     CDS             26001..28739
                     /locus_tag="PC503_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF2527328.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEHELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28858..29802)
                     /gene="manA"
                     /locus_tag="PC503_001323"
     CDS             complement(28858..29802)
                     /gene="manA"
                     /locus_tag="PC503_001323"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF2527329.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29975..31336
                     /locus_tag="PC503_001324"
     CDS             29975..31336
                     /locus_tag="PC503_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2527330.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31424..33313
                     /locus_tag="PC503_001325"
     CDS             31424..33313
                     /locus_tag="PC503_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2527331.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33328..33783
                     /locus_tag="PC503_001326"
     CDS             33328..33783
                     /locus_tag="PC503_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527332.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33842..34159
                     /locus_tag="PC503_001327"
     CDS             33842..34159
                     /locus_tag="PC503_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2527333.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34184..35446
                     /locus_tag="PC503_001328"
     CDS             34184..35446
                     /locus_tag="PC503_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2527334.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35551..36615
                     /locus_tag="PC503_001329"
     CDS             35551..36615
                     /locus_tag="PC503_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2527335.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36669..37847
                     /locus_tag="PC503_001330"
     CDS             36669..37847
                     /locus_tag="PC503_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2527336.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38038..39096)
                     /locus_tag="PC503_001331"
     CDS             complement(38038..39096)
                     /locus_tag="PC503_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF2527337.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39163..39534
                     /locus_tag="PC503_001332"
     CDS             39163..39534
                     /locus_tag="PC503_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF2527338.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39571..40245
                     /locus_tag="PC503_001333"
     CDS             39571..40245
                     /locus_tag="PC503_001333"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF2527339.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40494..41333
                     /locus_tag="PC503_001334"
     CDS             40494..41333
                     /locus_tag="PC503_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2527340.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41577..41673
                     /locus_tag="PC503_001335"
     tRNA            41577..41673
                     /locus_tag="PC503_001335"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41611..41613,aa:Sec,seq:tca)
     gene            41823..42530
                     /locus_tag="PC503_001336"
     CDS             41823..42530
                     /locus_tag="PC503_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF2527341.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42672..43508)
                     /locus_tag="PC503_001337"
     CDS             complement(42672..43508)
                     /locus_tag="PC503_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527342.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43696..44601
                     /locus_tag="PC503_001338"
     CDS             43696..44601
                     /locus_tag="PC503_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF2527343.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44610..45794
                     /locus_tag="PC503_001339"
     CDS             44610..45794
                     /locus_tag="PC503_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527344.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45909..47210
                     /locus_tag="PC503_001340"
     CDS             45909..47210
                     /locus_tag="PC503_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF2527345.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47164..48207
                     /gene="holA"
                     /locus_tag="PC503_001341"
     CDS             47164..48207
                     /gene="holA"
                     /locus_tag="PC503_001341"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF2527346.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48394..48660)
                     /gene="rpsT"
                     /locus_tag="PC503_001342"
     CDS             complement(48394..48660)
                     /gene="rpsT"
                     /locus_tag="PC503_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF2527347.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49238..49759
                     /locus_tag="PC503_001343"
     CDS             49238..49759
                     /locus_tag="PC503_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527348.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            49793..50569
                     /locus_tag="PC503_001344"
     CDS             49793..50569
                     /locus_tag="PC503_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2527349.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDKI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            50911..51864
                     /locus_tag="PC503_001345"
     CDS             50911..51864
                     /locus_tag="PC503_001345"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF2527350.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            51882..52901
                     /locus_tag="PC503_001346"
     CDS             51882..52901
                     /locus_tag="PC503_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF2527351.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            52932..53183
                     /locus_tag="PC503_001347"
     CDS             52932..53183
                     /locus_tag="PC503_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527352.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            53465..55270
                     /gene="lepA"
                     /locus_tag="PC503_001348"
     CDS             53465..55270
                     /gene="lepA"
                     /locus_tag="PC503_001348"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF2527353.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            55419..>56750
                     /locus_tag="PC503_001349"
     CDS             55419..>56750
                     /locus_tag="PC503_001349"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF2527354.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYT"
BASE COUNT        22330 a         6147 c         9754 g        18519 t
ORIGIN      
        1 aaatattttt aaattatcat ttaatgtaat ttaaatgaat tgaagatata tgtttattgt
       61 atgcaattgt tgtattttta ggttttttgt gattaattaa aaaattataa aaatcgttta
      121 catgttgatt tttaaaaaaa aaagatatag aattatatag aaagtaataa acaaaaattg
      181 gatttacggg agtggaatga aatgatgaat gttaccttaa cagatgtgaa agaggctaga
      241 gagaccatta agaacatagt aaaaagaact gacttacttg aaagtgttaa acttagcgaa
      301 aaaacaggag caaatgtgtt ctataaatgt gagaatcttc aaaaaacagg ttcttttaaa
      361 ttaagaggag cttgtaacaa aatagcgagt ttaacagatg aagaaaaggc aaatggagtt
      421 atagcttcaa gtgcagggaa tcatgctcaa ggagttgcat tgggagcaaa aatgactggt
      481 ataaaatcta caatagtaat gccagcaact gcgcctttag caaaagttag tgcaactaaa
      541 ggttatggag cagaagtagt tttaaatggt gcggtttatg atgatgcata tgcaaaagct
      601 gttgaaatac aaaaagaaac aggagcaact ttcttacatc cattcaatga taagtatgtt
      661 atagcaggac aaggaactat atctcttgaa attttcgaac aattagacaa taaagttgat
      721 actatactat gcccagttgg tggaggagga atcatctctg gtgttgctgt tgcagcaaaa
      781 gcattaaatc ctaatgtaaa aatagtcggt gttcaaactg caaatatacc ttcaatgaaa
      841 gagtcaataa aaaatggaaa agtaacaaca gcatttaatg atactacaat agctgatggt
      901 atagctgtta aaactccagg agatttaact tttgaaataa taaatgaatt ggttgatgaa
      961 atagtagtgg ttgaagagac agaaattgca gaatcaatat tatttatgat ggaaagtcaa
     1021 aaaatagttt cagaaggtgc tggtgctgta tgtacagctg ctatattaag tggtaagtat
     1081 gtaccagcaa aagatgaaaa tgtagtttgt ataatatctg gtggtaatat agacataaat
     1141 acgttatata gaataatagg tgttgcttta gctaaagaag gaagaagata ttcatttagt
     1201 acaattatgg aagataagcc aggaaacttt gctgagttaa ctagaataat aagtgagaat
     1261 ggtggaaaca ttttaagtgc taatcaaggt aaattatcag caggggaagc tctaggaaaa
     1321 caaagtgcgg aatttatatt agagacaata gattatgacc atatagctag aataaagaaa
     1381 gctatagaag aaaaaggttt taaaattata gaattataat aaaaagtgta tataatatac
     1441 aagaaaaata gtataatagt gtatgaagat acattttatg tgtattagat taacgaatta
     1501 ggaggatttt aaaatgaaac atgaagtaat acatactaat gatgcaccag cagctttagg
     1561 accatattct caagctataa aagctggaaa cttgttattt gtatctggac aagttcctct
     1621 tgtaccagag actatggaag tagttgaagg agatgtacaa gctcaaactg ctcaatcttt
     1681 aaaaaatctt aaagctatat tagctgaaag tggagctgat ttttcaaatg tagttaagac
     1741 tacagtattt ataaaagata tgaatgaatt tggggctata aacgaagttt atgctgaata
     1801 ttttggagaa aataaaccag caagagcttg tgtagaagtt gctagattac caaaagacgt
     1861 taaagttgaa atagaagtaa tagctgtatt ataaaaatac aatattttta atttgaaaag
     1921 gctgaaaaac tatattctag tgattcagcc tttttataaa aaaataaatc acaataaaga
     1981 acatgataaa tattgtcgaa ttaaaaaata aaattaaaat aaatattgca atatttttga
     2041 gaaggtttta taatgagtat ataatttgaa acgtgtaact attaaattag gcatgagttc
     2101 ttggatattt ttatcctgag gattcatgcc ttttttgtat tgaaattcaa aaatctattt
     2161 aataaggagg aagtactgtg ttaaattttt tcaagaaaaa taaaagctat aagttacatg
     2221 cagtagtgag tggtaacagc attaatattg agaaagtaaa cgattctgtg ttttcaaaaa
     2281 agttaatggg agatggagtt gcaattattc ctaatagtaa tgttgttgta gccccttgta
     2341 atggtaaagt aactgtgctt acagaatcaa agcatgcctt tggtatggtc tcagatgagg
     2401 gtgttgaaat attagtccac ataggaattg atacagttag tttacagggt gaggggttta
     2461 aaaatgaagt gtctcaagga gatactgtta aaaaaggtag tccaataata agttttgaaa
     2521 gagaaaaaat aaattctcag ggaattgatt gtacaacaat aataattgta ttaaatcata
     2581 gcgaattttc agaaataaat tgcatggtag aaaatgaagt tgttgcaggg caagatactg
     2641 ttattgaaat tatgaaataa taggaaggga ttaattcaat atgagagtag taaaaatctt
     2701 taataataat gcattatcta cagtaactaa tgataggaaa gaagctattt tactaggtct
     2761 tggtataggt tttaataaac gtccaggaga taaagttaat gaagataaaa tagaaaagat
     2821 ttattatgtt caagaccaca tgcaaacaaa atttttagaa ttattaaaaa atgttagtcc
     2881 agaagtgatg gatgcttcac aacaaattat aagtcttata ccaggaaatg agggaaaatt
     2941 taataataaa gggatattat ctttagtgga acatattagt tttgcaatag atagaatgaa
     3001 aaataatgtt tttttaccta atttaatgct tttggatata aagatgatgt attcaaaaga
     3061 gtttgaatta ggagtaaaag ctttagaaat tatatataga gtatgtcata tccatttgcc
     3121 tgaagatgaa gcaggttaca tagctttaca ttttgtcaat ttacaatcaa atgataattt
     3181 ggcatatgat actttaaaat ttgtaaaagg tagtattgat ttgattaaag aatgttatgg
     3241 attagaatta gacgaatcga gtttaagtac attacgtttt agaactcatc ttaaatttct
     3301 tgctcaaaga atttttaaga atgaaatttg tcaggatgat aaaatgattg aaatgtatga
     3361 ttatttaatt aacaatcatc ctaaaaataa agaatattta gaaaagttaa atgtatatat
     3421 tgaaaaggag tttaggtata aattagataa acctgaaaaa atttatctac tactacacct
     3481 aacaaaaatc ttataagaat gagatgaatt agtaatagaa atatataatt ttaggggggg
     3541 ataagattga aagaaaaact acttggagga ctggaaacat ttgcaaaggc aatggttcag
     3601 ccattaatgt atttatcgag tgcaggaata ttaatggtgg taggtgtact acttacaaat
     3661 gatatgttat taggagtact tccatttttt aaatgggagc caattcaaat atttggaagc
     3721 ctaatttata actgtataat ggctattatt aataatcttg ctgttatatt tgctataggt
     3781 attcctgctg cactagcaaa aaaagagaag cacaaagcag cgttaatagg atttatgagt
     3841 tatataatat accttacagc ttccaacact atgttaacat cactaggtca actagcaaaa
     3901 gaaagcaaga tgcttggact gatagggact ggacaagcta ctattttagg tattcaagtt
     3961 gtagatacaa gtgtatttgg tggaattatt ttagggtgta tagctggata tgtatttaat
     4021 cgtacaagca acaaaacatt taaaggagct ttacagatat actcgggagc aaattttagt
     4081 tttatatgca tgttctttgt atccatttta attggagttg tgagtaactt tatatggcca
     4141 ttagctcaac aaggaatagc ttctcttgca aatgtcatca aagatacagg tacatttggt
     4201 ttattcttat atggtttttt agagagaata ttagtaccaa ctggacttca tcatttaatc
     4261 tatacaccat ttcagttttc tgatttagga ggagtgctta aagttggtgc agatacagtt
     4321 tcaggagcct atgctatagt tatgacagaa atgaatttac cagttgagcg tttctcagat
     4381 agtatatact acatggcaac tggatttaca aagatgtttg gttatatagg tataggagct
     4441 gcctttattt atactgcata taagcaaaat aagaagaaag ttaaggcaac gattattcca
     4501 ctaataatta cggcagtatt agcctctgta acagaaccat tagactttat gtttgtattc
     4561 tgtgcaccat ttttattctt tgtacatgca gttatagctg gtctttttat agctttatta
     4621 aaaatatttg atgttactgc attatgtgga gggaacttat tagtatcaat tataatgaat
     4681 actacagtag gcgtagaaaa aacacactgg ccagtaatga tgatattagg acttgcacaa
     4741 attattgtat attttgtagt atttagtttt ttaattaaga aatttaatta taaaactcca
     4801 ggtcgtgaag atgagagtac agctacaggc gaagaacaat caaaacaact taatttagat
     4861 gcagggatag aaaatataat tgatgggtta ggcggaaaag aaaatattaa tacagtagaa
     4921 aattgcatca ctagattacg tgttaatgta aaagatgaaa gtaagattaa tgaagatata
     4981 attaatttaa cgccaaatag cgggattgta aggaaaggaa aagatataca aataattttt
     5041 ggacttcatg tgcatgaggt aagacgtgca gtagaagatt ttttagaagc ttattaaaga
     5101 tatatattta tatagcaagg gtaaataaca gctttaagtg ctgtttacta tttattaaag
     5161 atacatataa tttatagagg aggaataatt attatgatta ttactattgt tggtggagga
     5221 agcacattta ctccaggtat tgttaagtca attgcattaa gagaaaaaga gttagagctt
     5281 gaggaaattc gcttatttga cattgataaa gaacgccaag ataaagtagc tgtagttgtc
     5341 aactggatac taaaagaaga tgttaaaaca gatgttaaac taactgtaac taattgtgaa
     5401 aaagaagcgt atacagatgc tacatttata tttgcacaaa tgcgtgttgg taaatatgaa
     5461 atgcgtgagc aggatgaaaa aattccattg aaatatggtt gtgtaggtca agaaacttgt
     5521 ggttgtggag ggatggcata cggactgcgt acaatacaac caatgataaa ggttattgat
     5581 gatgtagaga aatatgctaa aaaagattat tggatattaa attactctaa tcctgctgca
     5641 atcgtttctg aagcttgtcg taagttaaga ccaaatgcaa ggattataaa tatctgtgat
     5701 atgccaatag ctattataga tatgatagcg gggtcattaa atatcaatga cgttcataat
     5761 atacgctatg attattttgg tctaaatcat tttggctggt ttacttcaat agattataaa
     5821 catagagact taatggaaga gattaaggaa tacataaaag aaaataaaat attattacca
     5881 aaatcttata tagaaaactt aaataaaagt cgtagtacag gaaatcgcca tgctgtaagt
     5941 agctggatac atgtttggga atctgtttat acaatgttag aaagcttccc aaaatatctg
     6001 ccaaacactt atttaacata ctatctttta agtaaagaaa cagtggaaca ttcaaacata
     6061 aatcgtactc gtgcaaatga ggttatggaa agccgtgaaa aagacttatt tgaaggtgtg
     6121 agacattact tagaaactgg agaaatttct gaaaaagcat tttatgcagg ttcacatgga
     6181 gattggatta gtgatttggc agtttcaatt aaaaatgata cacgtagtcg ttttttagtt
     6241 ataactgaaa atcgtggagc tataccaaac atgccatatg atgcaatggt agaaattcca
     6301 gcatatattg gtaaagatgg tccagaagtt attgctcgag gtccaatacc tctatttcaa
     6361 caaggattaa tgatgcaaca acttaacagt gaaaaattga tagtagaagc ttatatagaa
     6421 aatagttatg aaaaagcttt acaagcattc acattaaata aaactattcc aagtatgaat
     6481 gttgctaaag aaattttgga tgaaatgata gaagttaata aggaatactg gccagaatta
     6541 agatagtagg ataaaggaaa gggtttttat ttaataatta gatatgtttt cagagtcttt
     6601 tatcaaaatg tattcacaaa catatggcaa tatattaaaa taaagagtga tatttttaga
     6661 agaatggggt gatgcaatga acattataaa taaaattttt tgggaagaag ataggattgg
     6721 catgattaca aataatttag aggcagatac acatagccac tgtatgttac aactgttctt
     6781 agggatagaa gacagcattg aaataacagt caatgaaaaa ttagttaaat gtaattgtat
     6841 catagtagat aaaaatatct ctcattcatt ttcagcaaga aaaaaagttt attactctgc
     6901 tattattgaa cctacatcta tatatgcaga acagcttacc tcaaaaatga atgattttgg
     6961 ctactggata tgtgacaatg atggattaga gaaattacgt caacaaggaa cttttttgat
     7021 agataactct agtaaagaac aatatttaag atttatggaa atgcttaata actatttgaa
     7081 tatacctata actctcaaac attatgatga cagaattact gaattgctca atttattacg
     7141 tacttgtaat tgtgataatc atactatttc aagttttgca gataaagtgt ccctatcagc
     7201 aagtagatta tcacatctgt ttaaagaaca aatagggata cctttaaaaa gctatatctt
     7261 atttcatcaa atggagtgtg cttttagaga attactttct gggaaaaatg ttaccgaagc
     7321 ttctatgact gctggattcg atactccatc acactttgca gggacagtta agcgaatgat
     7381 gggaatgcct gtttctttat ctttgaaaga tagcgaattt ttgaaagtat attaaatatt
     7441 ctcgttatat aatgaagttg tactaagaaa ggggctttgt tatgaataaa gaatatttag
     7501 aggaaacaaa aatgttaaat tataatgaac cacaacttaa gcttttggta tcatcaaaga
     7561 attggttgga attagatgat tttcataaaa taaaatctat ttatgagttt gtacagaatg
     7621 atattttatt tggatataat gcttctgata tgttaagcgc aacacaggta ttaaatgatg
     7681 gtatgggaca atgcaataca aaagctactc ttttaatggc attattacgt gcagtgaata
     7741 tcccttgtag gcttcatgct tttgatgtaa caaaagattt tcaacgagga gctacatcca
     7801 aattgatttc actattagca ccaaaatata ttcttcatac ttgggtagag gtattttatc
     7861 aagataggtg gattgctctt gagggtgtca taactgataa aaaatattta gaagcaattc
     7921 agaagaaatt ttttaatcat ggtggaacat ttaaaaagta tgcaatagct acaaatgatt
     7981 tgaaaaatac atctattgat tgggatggta aagatacttt tatccaaaaa gaagctatcg
     8041 tgtatgatta tggtattttt ccatcaccag acgtattttt ttctactcat tcacaacata
     8101 tgtcaaaatt aaaaaatttc atatatgtac atcttatcag aaaaataatg acaaaaaatg
     8161 tatgtaaggc tagaaacaat tatattgata aaaacgaatg agtgtttaag aggtaactat
     8221 ataggaaata tatagaataa ttaaaactgt actggttaaa atgaataaaa aggagttatc
     8281 acagagcaaa cttaaattgt tcataggata actccttttc tgtattaact tctaataatt
     8341 tgatgtcttt ttataaaaca tatagataca attaaaccag taaatgcaag agtagctgct
     8401 attgaaaatg caacatctat tccatgaatg ttagacagca tgtttgaact catatgagct
     8461 ttcttagtag cacttgtcat tatagtaata agtatagcag aacctatagc tccagatatc
     8521 tgacggagtg tgttattaat tgctgtggca tgagatataa gttctctatc taatgtttta
     8581 attccccatg tagttaatgg cattaaaacc attgaaatac caatcatacg aatacaatac
     8641 atcaatgaca catgaattaa agatgtatct ctgcctaaaa aagcgaagga taaagttcct
     8701 aaaaacaaac atcctgttcc taatattgat agagcatgag gtccatattt atctaaatga
     8761 cgtcctgcaa ttggattgag tacaaccatc aatatagcac caggtaacat taatgaacct
     8821 gaagataatg cagaaaatcc tcttacagat tgaacgtaca gaggaatcat taatgtagca
     8881 gacatcattg aggcatatac aatcataatt aatattgtag aaataagaaa tggtttattt
     8941 ttaaaaaccc tcaattctaa aaaaggttct ttagatttta attgacgcaa tgtaaataaa
     9001 attaatgaca taattcctat taatattggt aaatatgtgg caatattagt ccacccataa
     9061 ttaccttgat tagtaaatcc aattaataaa ccaccaaaac ctagagatga tagtactatt
     9121 gaaggtatat ctaattttag tttttgagtt tccccaacat ttcttaatag aataaatgat
     9181 agtataacat ctaatatagc aataggggaa agaaacagaa ataaactatg ccaaccaaat
     9241 gaatctacta accatcctga taaagttgga cctattgctg gagcaaatcc tactgtaata
     9301 ccaactaaac tcatagctgc accacgtttt tcctcagggc ataaatagag tataataact
     9361 tgtaaaagtg gcattagaga accagaaccc attgcctgca acacacgagc aatcaacata
     9421 gttgaaaaat tattagaaaa aagtgcaata atacatccta tagaaaagat agacattgat
     9481 gtaataaata actttctagt actaaatcga tttattaaat aagctgttgt gggtacaata
     9541 atacctgcaa taagtagata aattgttgtt aaccactgac caatatcagc agtaatttta
     9601 aaatctgaca ttatattagg taatgctgtt gacaatagtg tttgactgag agaacttata
     9661 aaagcaccag tcattacaat tgctattatt aaatttcctt ttttattgtt actttgggtt
     9721 tccataattt ataacgtctc cttttttaat tgatttttaa tgctgttcaa taaaagtact
     9781 tttggtctta aagtgtcttc tttttctaaa tatgcaatca ttgcatccat aattaaagaa
     9841 tcatattgtt gattttttcc ttcgacgtat aattttttta ttgcttctag taatttagga
     9901 ttttcaagga gagaagtatc agttttgatt agttcttcta tatcttgtat cgttttaaaa
     9961 aatagcgatt tattatgaag ggaaaagtaa acttcatctt cttgtttatg taaaaacatt
    10021 gatttttcaa ttaaaggatt tagattatcc atattttcta caactaaatc tagaatttgt
    10081 atagtaaatt tggcaataaa gtatacattt atttctcttt tttgtacatg aataatgtat
    10141 ataaactgat gaattagagc atccaataag aaaactaaat caaatataat tttttctatt
    10201 ttatcaccat agttatcaaa taagcttagt ttgtattcat tcaataagtt agctcttgat
    10261 tttgtttgca atttacttgt agccttacgt tgctcttcag aaaagttttc tcttatatag
    10321 gtatttatgg tagttctaga aaaaatattt ttccatacag caattatctt tctgtttaac
    10381 ttttctgatg atggaatgtc attattttca tttatggaat gtataatttc taaaaacttt
    10441 tcatcataat aattgattat ttcgcagata aaactttcct tagtttcaaa atgcttgtaa
    10501 aaagtagctt tagacatttt acactctttt acaacatccg atattgaagt attttgaaaa
    10561 cctttttggt caaaaatttt ttgtgcaata gttataatga gcctttgttt ttctgtcact
    10621 ttattatctc ctttcacgca aaaacgttta gtactatata gtacctacaa gttttgataa
    10681 atatattata catcatttgg aaaaaaaatc aatatataga ctgtaatatg aaatttttga
    10741 aaaatttgtt gttattttta gtcgtataaa aaagaaactt aagagtttct taagaattgt
    10801 ttaaagaagt tgcaataaat tagtggtatg attatagtat gaaagagaat gtcttgaaat
    10861 ttttctgtat caaattccaa ttatggaggt gtagtatatg aaaaagaaaa tttgtgtagc
    10921 aataattttt gctctattta tagtttttgt agaaatgttt attgatagct ctagcgaagg
    10981 aagtaaaatt atgacagctg aattaagtaa atacaggaaa ggcgtaaatg tattatcaat
    11041 aaacaatatt atagtagcga ataaaaaata tagtttgccc aaagattatt ctcctcagga
    11101 aagcagtgaa gcgagagatg ctttttataa aatgaataaa gatgctcaaa agtcaggatt
    11161 aaatttaaaa gcttttagta catatagaag ttatgaatat caagatagat tatttaagtc
    11221 atatgtaaaa gaacatggag aaaaagaagc aaatagattt tcagctaaac ctggagagag
    11281 tgagcatcaa actggacttg cttttgatat tggaggagat gaccagtctt gttgggcaaa
    11341 taaaaagttc aacaatacaa aagaagctaa gtggttgtat gaaaatgcat ataaatatgg
    11401 ttttatactt agatatccag aaggtaaaga gaatataaca ggatatatgt atgaatcttg
    11461 gcactataga tatgttggaa ctgaacatag caaaaacttt gcaatgaata atttgacttt
    11521 agaagaatat ttacatataa attaagagat ggtttgttaa aattaggtta aaataaaaaa
    11581 taacctagac tattagctgt gtaaagtgat ataatgtaaa tacaatttaa gataactact
    11641 cgaaggggag tagcttacac gaaagtggta attaatcgtc aagacagtag aaatactcgg
    11701 ttaattagca agggattcct tgatagcaag accttcaaaa taagcattag gtatgtttgt
    11761 tttggggtct ttttttattc aaggaatttt tatttaaaaa aatttaaatt tcaagtatac
    11821 ataagagccc ccaaacataa aataaattta ttgaagagga gggcaacaaa tgtcttacaa
    11881 aagtacttat caagaagtaa ttaaaaattt agactcaagt ttatctggtt tgagtaaaga
    11941 aagagcagaa gagttgttag aaaaaaatgg agctaatgaa ttaaaagaag cagataaggt
    12001 tcctacttat aagcttttcc tagaaagttt taaagaccca ttagtaataa ttctattgat
    12061 agctgcttta gtacaaatat ttttaggtga aacagtggag tctataataa tttttgcagt
    12121 tattattata aactctgttc tgggtgttgt acaaacaaaa aaagcagaaa gttcattaga
    12181 aagtttgaaa aatttatctg caccaaacgc aaaggtaata agagacaata aaaaaatgac
    12241 aattccagca aaaaatctag tagttggaga tattgtattc ttagaagctg gcgattacat
    12301 accagcagat ggaaggctta tagaagcaca atctctcaag gttgtagaag ggatgttaac
    12361 tggagaatca gaaccagttt taaagcatat agaaaaaata agtgaagatg taagtttagg
    12421 tgaccagaaa aatatggtat ttagtggtgc tgtagttgtt tatggtagag gttcttttgt
    12481 agtgactgga acaggtatga atactgagat gggtaaaata gctgggcttt tagaaagtgc
    12541 tgaaaataaa cttacaccat tgcaacaaaa aatagaggat tttagtaaaa aacttggtgt
    12601 aggtattgta atacttgctc ttttaatatt tataattcaa gtagcaagaa attactttat
    12661 ggctggaaat ggagaaatga cacaaattat tttagattca ttcatgttct ctgtagcagt
    12721 agcagtagca gctataccag aagctctatc atcaatagtc actatagtat tggctgttgg
    12781 aacaaatagt atggcaaaaa aacaagccat aataagaaaa ttaccagcag tagaaacttt
    12841 aggttcaaca agtgtaatat gtactgataa aacaggtact cttacacaaa ataaaatgac
    12901 agtagttgat tattatatgt atggaactaa taatgatgag ttagataaag aaaaagtaaa
    12961 ctattcttat catgctaaat tattgactat ggtttctaca ttgtgtaatg actctcatat
    13021 aactagtgat ggtaaagaag ttggtgaccc aacagaagtg gctttaataa attattcaag
    13081 taaaaatgat ttagattatg ataaattaag aagtaagtat atcagaataa atgaaatacc
    13141 atttgactca gacagaaagc ttatgtctac tgtaaatagt atatatggag attatataat
    13201 gtttacaaaa ggtgctccag atattgtgtt tagtagatgt aaatatgctt tgaaaaatgg
    13261 ttcaaaagta gatataacag atgagataat agaagaatat aaacataaaa atgaagagtt
    13321 ctcaaataga gcacttagag tattagcttt tgcaataaaa gatgtcccag aagaagattt
    13381 tataccttca attgatgacg aacatgacat gacattggtt ggaataatgg caatgataga
    13441 cccaccaaga gaagaagtaa tggatgcagt aaaagaggca aagagtgctg gtataaaaac
    13501 tgttatgata actggtgacc ataaaacaac agcagcagca attgcaaaag agattggtat
    13561 aatggaagaa ggagacttgg ctcttactgg aaaagagctt gatgctttga gtgaagaaca
    13621 actatatgaa aaactagaaa atataagtgt atatgccaga gtctcgccgg aaaataaaat
    13681 tcgtatagta aaagcatggc aacataagaa taatataaca gcaatgactg gtgatggtgt
    13741 taatgatgca cctgcattaa aacaagcaga tataggaatc ggtatgggaa gtggtactga
    13801 tgtagcaaaa gatgcttctg ctatggtatt ggttgatgat aactttgcaa gtatagtaaa
    13861 tgctgttgaa gttggtagaa cagtatacag taatataata aaatcaatta cttatctatt
    13921 tgcaggaaac ttaggagcta tagtatccat agtatttgca gtgtttgcag gttggtcaaa
    13981 tccatttaca gctttacaac ttttgtttat aaacttagta aatgactctt taccagcaat
    14041 tgcattaggg tttgaaaagt cagaaaaaaa tataatgaat aaacctccta gacacccgga
    14101 tgaaagtata ctagcaggag gaacattgaa ggcagttgct ataagaggtt gtataatagg
    14161 tgtagttaca ataattgcac aatatatagg attacaagta tctccagaac ttggagtagc
    14221 aatggcattt tcaacattga tattagctag aataatgcaa acattacctg cacgttctaa
    14281 taatcaaaca gtaataaaat taggtttttt cagcaataaa tacgttatag gagcagtttt
    14341 agtctgtctt gggctttact ctttaacact aataccagtg ctaagaggaa tattctctat
    14401 accaacaacg tttggattgt accagttggg gatttgccta gggttagcat taatttcatc
    14461 aatattaatg gaacttaaca aattaataaa tagaagtgaa gtaaaataat caaaaaatta
    14521 aagggcatat tgattttaac aatatgcctt ttataaatag tctaatttat tctatattat
    14581 cgattatttg gaatgctttt ataacttcag gtaattcttt ttcttcaggc attctaaatc
    14641 ttataaaatt tttatcaagt ccagtaaaat cacttccaga tataactctt atttttaatt
    14701 tagcaaactc ttgttgtaaa tctatgtcct tgtttttatg ttcaactgtc ataattgata
    14761 cagtatcact agtttcagct atattaaggt ttttccatgg aattaataat tgatttttta
    14821 tatcttttgt tttttctttt aattcttcta taaattgaac atcatctaat aaatttgctg
    14881 caatactacg agatatttca gacacttcgt aaggagtaga aatcttttta atagggctaa
    14941 caagttgttc tggaagaact gcatatcctg ctcttagtcc tgctaaacca aatccttttg
    15001 aaaatgtttt taaagcaatt acattatcat aattatttag aagcttgaca gctgaatttt
    15061 cttttggcat gtattcacca taagcttcat ctaccataac tgctatatca tatttagctg
    15121 cttcccttac tatattttca attgatgata aaggtataat ttgtcctgta ggattgtttg
    15181 gattgtctat gtaaattact ttatattctg gatttatttt ttcaataaat tctttttcat
    15241 taaacttgaa attatcctct ttctttaaaa gaacataatc ataagttgca ccatgcattt
    15301 ttatatctgt ctcatattct gagaactgag gtgaatatcc taaaacttta tctccctttt
    15361 caataaatag tctatttaaa aggtaaataa catgtataga accatctgcc aaacaaattc
    15421 tgtcagtatc taatgctata aaatctttcc aataatcgac tatattatct tttaaagcaa
    15481 ttgaatgagg atatcctctt atcatatcaa attttaaagc attaaaagct tctacagctt
    15541 tgtttgagta agacacggta tttatacctt caccacagtc tatctcgaat acatcttctg
    15601 aatgtccaga ttctattgca taactttttt tcaactgcat ttcaatagct ttgttaattt
    15661 ttagtttcat actttatcac tccttattta gtcaataata aatgttataa aagttgctag
    15721 atttaaaata ttatgaaaat atataatagt aaaaatgaat ataaatatta taatagctca
    15781 ctttatttaa tatgattata tatcatatat tgtaaaattt ctagcattat aagactataa
    15841 attgaaaata ttcagaaaaa tactacaaga aacgatttat tttgctctta aaataagtta
    15901 aatgaatgtt attaattttg taaattgaaa tagtttaagt ataaagttat gatataatct
    15961 aataagggta attctttaga ttatattaag gaaatatagg tatacaataa aaagttatgg
    16021 agttggatta tgggatataa attaattgta acagatatgg atggaacttt attaggcaat
    16081 aatcataaag ttacagatga aaataaaact gcactacaaa aagttataaa aagcggtatt
    16141 aatgtaactt tagcaacagg aagagccttc gattcagcta aatgcaatgt agattttctt
    16201 aaagaggaca tgccaataat agcttgtaat ggttcattaa taagagagca aaatggaaat
    16261 ataatatatt caaataagat tgatacaaga acatgtttaa acattttaga tgtattagat
    16321 aaatacgata tttactacca atgtaatagt atagattcta tgctttcgaa aaaaatagaa
    16381 ggacgtgaag atagattaag tgtattttta ggctctgaaa cagaagtaat tgtaaaagat
    16441 gatttgagag aagaaatctt taaaaaagat atactaaaat ttgtaatcat agaagaaaaa
    16501 aatccatcta ttttggatga aataagaaaa gaattgagaa aagttcaagg aataaagata
    16561 acctcttcat ggccaaacaa tattgaagtc atgaatgaag gtgttgataa aggtaatgca
    16621 gttaaaattt tagctgaaaa aatgaatata gacagagaag atataattgc atttggagac
    16681 aattacaatg acatagaaat gataaagttt gctggtcttg gggtagctat gggaaatgca
    16741 gaagaattga ttaaacaaga agctgattat gttacagata caaatcaaga cagtggagtt
    16801 gcaaaggcaa tttataaatt cctagagtta aaagaatcac ttagctctta aaacagtata
    16861 taataggaaa aaataggttg actattttgt agatagtaat tataatacaa atagataaaa
    16921 tataaaaatt tagattcagt gaaaaagaga gtagatatag agaaaatctc agcgaattgg
    16981 gggatggtgt gagcctaatg ataacacttt atattgaaaa gaactttgga gaatactact
    17041 tgaaattcag tatggtagta ggtaatctcg ccttaagaga atagagtggg taaacattgt
    17101 ttaccaacta gagtggtaac acggaatatt tcgtctcttg gtctttttga ccaagagatt
    17161 ttttagtttc attgagttac aagacttata attaaaatac aaaaaattaa aatatgaggt
    17221 gaaagttatg aaattatggg gtggacgctt tagaaaagcg gaaaatcaac ttatggaaga
    17281 atttaataaa tcttttggct atgattgtgt actgtacaaa aaagatatcg aaggaagtgt
    17341 agcacatgtt catatgcaag taaaatgtgg acttttaaca gaagaagaag gaaagtctat
    17401 aacagaaggt ttaaaaggga tacttgaaga tgtagaaaat ggaaagttag tattggatgg
    17461 agagtatgaa gatatacata gttttactga gataaattta attcaaagaa ttggagatgt
    17521 tggcaagaag cttcatacag cacgtagtag aaatgaccaa gttgcagttg atatgagatt
    17581 gtatgctaaa gaaaaagcaa atgatttggt ggatttaata tctgaattta aagctactat
    17641 aaaagatgtt gctgacaaaa acccagtgat gatgccaggc tatactcatc ttcaaagggc
    17701 acaagtagtg acatttaagc atcacttaat ggcatattat agtatgtttg atagagatga
    17761 gaaaagaata aaaaatgcta tagaaatatt agatgaatca cctttaggct gtggagcttt
    17821 agcaggaact acgcatgata tagatagaag tataacttgt gaacaattag gatttaaaaa
    17881 agtagtagat aattttatgg atggagtaag tgatagagat tatttactag agctaatgag
    17941 tgatttttca attataatga tgcacttaag tagattaagt gaagagttga tactttggag
    18001 ttctcaagaa tttggatttg ttgagataga tgatttatat acaactggaa gtagtataat
    18061 gcctcagaag aaaaatccag atggtgcaga gcttataaga ggtaagactg gtagagtata
    18121 tggaaactta tttggtcttt ttacagtaat gaaaggaata ccattagcat ataataaaga
    18181 catgcaagaa gataaagaag gttttttcga tagtgtacat actcttgaaa tgtgtataca
    18241 aataatggat agaatgatag ccacactaaa ggtaaatgag gataaaatga aacaagcagt
    18301 aaaaaatggt tttttaaatg caacagaagt tgcggattat ttggttaaaa ataatgttgc
    18361 ttttagagat gcacatggta tagtaggaag tatcgttata tattgtgaag ataataaaaa
    18421 agcaatagaa gatttaacat tagaagaatt acaaaagttt tcagatgctt ttaaggaaga
    18481 tatttatgat tttatcgact atgagagtat attaaataag ggaataaaaa agaatttaaa
    18541 ataatgtatt tatttttaaa agctgtaaat ttgaatgtta tcatttaaat ttacagcttt
    18601 ttattgtgta agattttatt atataaaagt aagaaactta aaaggagtag tatttaaaat
    18661 aaatacaaat aaaaaattat tattaaaatg ataattaata tcaataagta ttgacaaaat
    18721 tatttctaaa tactattata tataatataa ataataatga aaatcaatat caaataaatg
    18781 ggaggaaatc taatgaactt attagtgatt ggtggtcatg aaagaatgga aaaagattat
    18841 atggttatgg ccaagaaaaa aggttataag acaaaggtat atactaccat gtcatctaaa
    18901 ttaaataatt ctataggaaa accagatgca gttgtcatac ttacatcaac tgtttcacat
    18961 aagatgtcta gaacggttga gtctcaagct aaaaaacaag atatattaat cgtaaggcat
    19021 aaaaatagta gtaaggtagc atttaatgaa tgtctagata tggttgatga atgtctggga
    19081 aattgttcaa aatgtaagct taaagacaaa caaaaacaaa aaaatatata ggtataaaaa
    19141 atacataaac ataaaattaa aagtactgag ataatagtta taattattat ctcagtactt
    19201 ttagatttat aaggataagt atagtataaa ttttttatta taatttccaa ctacttgtta
    19261 ctttttcata ttttttttac ttctagcttt ttttcttttt ttcttcttta tatttgaagc
    19321 tattataaat aaaactaaaa gcactagaat acctgcaata atcttaacaa aagtcattaa
    19381 aacattattt tcagtcaaaa atggaagact gctatcaaga ttattttttg caattaagtc
    19441 tatactgttt tctagtttac cattattata tacatttaaa gtaccaacct tagctccttt
    19501 ttttataggc aaatcaattt tatttaactc tgttttggta tcataattgc cttgagattc
    19561 atctttttct aagaatatcc tataactatt ttttggttca taaatcaatt catgttgttt
    19621 tgtaaacaat acttttttag tatctgtgta tttttcttta tcaacaatag tagcacactt
    19681 aaagttatca aatccataat caatcagaat acgtgagtct aaatataaat cagcattagt
    19741 tgaattaaat acagcaacga taactcttct gccatctttt acagcactcg ataaaagaca
    19801 tttaccagca gcatcagtat atccagtttt tataccatca actatatcat attttatatt
    19861 tataggttga cctttgtatg taatcttatc atgtgatgtc aaaaacttat tagtgtttac
    19921 aaagtatctc tcataaggat atgcttttgt agcttcaaat ttaagtgact tagtttttac
    19981 aatttgtcta aaagtatcat tattcatagc ttctctagct atgagagcca tatcatgagc
    20041 tgttgtgtag tgatttgggt ctggtaatcc atgaggatta ttaaaatgag tattagtagc
    20101 tccaattttt tttgcctcag agttcatgag gtcaataaat ttttgtacat tgccaccacc
    20161 aacatatcta gctaatacaa aagcagcatc attagcagaa tgaaccaaaa gagcatctag
    20221 taactgcttt acagtaaaag attccccatt ttttagatac atactagagc catctatttg
    20281 aggtaaatct ttaatttcta ttacttgatt taaatcttta acctccttta gaactaaaca
    20341 agctgtccat actttagttg ttgaagctgg ataaagctta gaatttccat ccttattata
    20401 tagtattttg ccagactcat agtccattaa aactgcatgt ttagcaacta tagctggttc
    20461 attatctgca aaagagatat tagagcttcc taaaaatgaa gtaaatatca ataaacagat
    20521 taataaaagt gataaatttc ttttcattgt gagcctccaa attttaaatt catcttttag
    20581 tatagcatat atttgtcaat aattaaaaga aaggagtgat taatatatga aaaaaaaggt
    20641 aaaatttatt tcgttttttg ttttatttat tttaataata tcatcaataa tcgtttataa
    20701 atcgcttatt ttcaaagatg atatttatgt tgtaagtaaa aaaaatttac ctaatgaaaa
    20761 aacacatgtt gtagagaatg aaattaaagg tgaagataat aatcacagta aagtaactaa
    20821 agacatagat aaaaattttc aaaataataa aataactata tacataagtg gagcagtaaa
    20881 tagacctgga attgtaacta tagagtcaga caagagactt tatgatgctg tagaattact
    20941 aggaggaacg acaaaagaag cagatttaaa tggagtcaat ctatcagtaa gattagaaga
    21001 tgaacaacat tacataatac ctaaaatagg tgaagcaaca tctgttacaa gtaatgatga
    21061 ttccaataaa ctaaatcaga agaatgagtc aagaggtgag cctaaaaata aatccaataa
    21121 aaatatatct aacgaatcaa aagtaaatat aaatgtagcg acgatagaag agttggattc
    21181 tctacctggg gttggagaag ctacagccaa taaaatttta caacacagag aagaaaatgg
    21241 acagtttagt tcaattgagg aaataaaaaa tgtaaatggt attggagata aaaagtatga
    21301 aaatataaaa gatttaattt gtgtagacta aaatataata caaaacttac atatagatat
    21361 gttattataa atatgtatgt atatgtgtgt acatgtggaa atttagtaaa ggaggcactt
    21421 ttatgaaaaa agaacaaaaa aaacttacag agatgacaac agcaggtggt tgagccgcta
    21481 aaatagggcc agaggttctg gcatcagttt tatctcaatt gcctaaaaat gataatatag
    21541 aaaatttatt agtaggacta gatacagcag atgatgctgc agtttataaa ttaaatgatg
    21601 atatggcact tatccaaact ttagacttct ttacaccaat ggtagatgac ccatacgtat
    21661 ttggtcaaat tgctgcatca aattcactat cagatgtata tgctatggga ggcaaacctt
    21721 tggttgctat gaatattgtt tgttttccat catgccatga tatggatgta cttgcagaaa
    21781 tattaaaagg tgggtttgat aaagtgaaag aaagtggagc acttttggtt ggagggcata
    21841 ctgtagatga caaagagcct aaatatggtc tttcagtttc tgggattgta agtccaaata
    21901 aagttttatc aaatgctact gcaaaacctg gtgataagtt aattataaca aaaccaattg
    21961 gagtgggtgt attaaataca gccatgaaag aaggtatggt agaacaacat atagcagata
    22021 aagtaataga aataatgata catttaaata aatatgcagc aatgagtttt gagaaatttg
    22081 atgtaaattc ggttacagat ataactggtt ttggtctact tggtcatact ttagaaatgg
    22141 ccaaagcttc tgaagtaagt attgaaattg aatcaaaaca tgtaccaatt attgaaggtg
    22201 caatagaaat ggcacaaatg ggaattatac ctgctggtat gtataaaaat atgcattatg
    22261 tatctaaaga tgtagaagtt gtaggaaata tagaagttgc agttcaagat attttatacg
    22321 acccacaaac atcaggaggg ttgttaattt cagtaaaaga agaacttgca gaggagcttg
    22381 taaaagatat gaaattaaat ggagcaatag aagctaaaat tataggttct gtagttccaa
    22441 aaggggaaaa atatattaca gttttataaa atattataga gaaagagtga ttgttttgag
    22501 caaaagagaa ttgtttgcaa tgttgccttc agttgatgaa gtattaagtg ataatagaat
    22561 tgtagaaata ataaatgaat atcctagaag tttagtttta gaatctgtga gagaagtaat
    22621 agatttaaaa agacaattta tattaagatt aaaagaagat gcatcaaact ctgtaacaat
    22681 agagtttggt gaaataatag aatctgcaat agagagagtt aagttaaatt actcattatc
    22741 tttaaaaaaa gttataaatg caactggtac agttattcat acaaatttag gaaggtcttt
    22801 acttagtgaa gatataaaag atgaattatg gtgtgctgct tcaaggtatt caaacttaga
    22861 atacgatttg gataatggag aaagaggttc aagatactct catttaacta gtacaataaa
    22921 aagacttact ggagcagaag atgtactagt tgtaaataat aatgcagcgg cagtacttct
    22981 tgtacttagc acaatggcta aaggaggaga agcaattgta tctcgtggag aattagttga
    23041 agtaggtggt tcatttagga ttccaagtat aatggctctt agtggtgcag aattagttga
    23101 agttggttca actaataaaa ctcatttgaa agattacaag gaggccatta cagaagatac
    23161 aaatgtattg atgaaggttc atacaagtaa ttatagaata atgggattca cagagagtgt
    23221 ttctatagaa gaattggtta atttaggtaa aaaatataaa ctacctgtaa tagaagactt
    23281 aggaagtgga gtttttatag atttatcaaa atatggttta tcttatgaac caactgtatt
    23341 ggattctatt cgacaaggtg cagatgtagt aacttttagt ggagataaga tgcttggagg
    23401 tccgcaagca ggtattatag ttgggaaaaa agagtatata gaaaaaatga agaaaaatca
    23461 acttactaga gcacttagag ttgataagct tacaatatgt gctcttgaag caacattgag
    23521 aatgtattta gatgagacaa aagctataga aaatatacct actttaaaaa tgttgacata
    23581 taaaattgaa gaattagaag taaaagcaaa taaactattt gaaaaaataa ctgctttaaa
    23641 cttaaatgca aacataaata tagaagatgg attttcacag gtgggaggag ggtctatgcc
    23701 tcttgaaact ataagtacaa aggtaatatc aataactcct gaacatatga atgtttcatc
    23761 tttagaaaaa aaactaagac ttagtgaagc acatataata gccagagtgt atgataataa
    23821 atatgtacta gatgtaagaa ctatatttga tgatgaattt gatgtaatag ttgaggaatt
    23881 gagaaaagca tttaattaaa taaatttgag ttaataaata ttaaatttag aagtataagt
    23941 atgaagtttt gattaaaaaa tagctacaca cacttgtgac tttagtcata gcaggtttag
    24001 agggggcaaa aaatgaaaaa tgtagtaatt ggaacagcag gtcatattga ccacggaaaa
    24061 actactctta taaaagcatt gactggaaga gagactgata cgttagatga agaaaaaaag
    24121 agaggtattt caataaactt aggatttact tattttgatt taccaaacaa tagaagagct
    24181 ggaattgttg atgtcccagg acacgaaaaa tttataaaaa acatgttagc tggagcatca
    24241 ggaattgata tagttttact tgttgtagca gcagatgaag gggttatgcc acagacagtt
    24301 gagcatttag atattctaag ctttttaaat atcaaaaatg gaatagtggt tctaactaag
    24361 tctgatactg tagatgatga atttagagag ctagtaaaag aagatatttg tgaaaaaata
    24421 aaaggaactt ttcttgaaga tgctgaaata attgaagttg attctatatc taaaagaggt
    24481 atagacactc ttattgaaaa aatagataaa atgagtgatg atatagaaga taaaaatgaa
    24541 aactctccag caagacttaa tatagacaga gtattttcaa taaaagggtt tggtactgta
    24601 ataacaggca ctttaataga aggaaagata agtatagaag atgatttggt tatatatcca
    24661 caggtattaa aaacaaaaat aagaagtata caagttcatg gagaaaataa agatacagct
    24721 tatgcaggtc aaagaacagc aatcaatata tcaaatgtaa aagtggatga tataaaaaga
    24781 ggagatgttt tagctgcacc aaactcattg gaggaatcaa tgatgttaga tgtaaaatta
    24841 tcattggtaa atcatttaga taaaggatta aagcactggg atagattaag attgtatcat
    24901 ggaactagag agatactttg tagagcagtt ccactagata aagaattaat tgaaagtgga
    24961 gaaagtggct atgttcagtt gagacttgaa gaaagcatag tatctaagaa aggtgatacg
    25021 tttgtagtga gacgttattc tccaatggaa actataggtg gaggtgtaat aattgaccca
    25081 tctcctaaaa aacataagaa atttgatgaa aaagttatag aagcattaaa aataaaagaa
    25141 aaaggcgaac taaaagatat aatagaagag tacttaaaaa ggaatttaaa aaattatcca
    25201 aatataaaag aaataatgag ctatagtggt gctcatgaag aagatgtaaa aagagcgctt
    25261 gaaacactta tatcagaaga taaagtattt attataggaa atatgtatat gcatataaat
    25321 caatacaata aattaaaaga aaatacaata aagcttttaa gtgagtacca taagaagtat
    25381 aggcttagaa aagggatact aaaagaagaa gtaaggtcta agatagagag taattttaag
    25441 actagggaga tggatatttt attagaaaaa ttgtctacag aaaatgctat aaaaatagaa
    25501 aataatatag tatctctatt agattttgag gttattttaa atgataagca aaaagaaata
    25561 gcaaaaaaaa tagaaaaaag attaaaatca tgtggagttt cttctatact gacaatagat
    25621 gaagtttctg aaggaaatca taactatgct gaagtattgg agtcaatgat aggtaataaa
    25681 gtagagaaat tagatgattt gtatataatg gacaaagata tttatgaaaa tgcaaagaac
    25741 attttgataa attatataaa agaaaataaa gaaataacat taggagaata cagagatttg
    25801 attgattcta gcagaaagaa ttgcatgatt atattggaaa acttcgatag aaacaaaata
    25861 actaaaagag tagaaaacaa aagaattttg ttttagcaga aaatgtctgt ttttgcttta
    25921 aggtataaag aaggaattat aatgtcgagt atcgtataat taattagtat aaaatattaa
    25981 ttaagaggaa gtgtaaagta ttgaagaata taatacctga tgtaaaacca gatataaaag
    26041 aaagagaaga catgagcctt ttatttataa taatgggctc agtactttta ttatttatta
    26101 taaaagatat agagaaatat gaaactttat tacatgccat atatacgata tttttagtag
    26161 ctacaggagt aattatattt aatactacaa aatttaaagt agattcattt tctacatttt
    26221 taggattaat ttttatagct actggagtat tggagtgtat atatttattt aattccttgg
    26281 ggattaaaac taagtctata atggagatta acatcacaat atcagcaata acagatttat
    26341 ttcctatact gggtgtatac ttaagtttta aatttgttaa ggataacaaa caaatttatt
    26401 caagtgtaat tttatttata gcaactgcta cattaacaat aacatcttta ttcataatat
    26461 caggaatttg tgactatctg ggaaatggta aatcacaata tgctttagga gttataatat
    26521 ctatattcat aataattatt tctatcatta gtggaattga attaaattca agttcaaata
    26581 aaggtaaatg ggaatatgat gaaaaaaaga tttttaacag aataatagta ataataatct
    26641 tatcaagagt tccaaatcta ttgcatatag ttattgataa tagaaatgta gagaggatat
    26701 tatcacaaat aataataaat gtagccttat attatttata taattacata gtatctaaga
    26761 atattaagaa aacagcactg gaattgcatg atacgaatga agaattaaca aaaaaaacgg
    26821 aaagtttaaa agaaaagaat aaaaaattaa tctatgagac agaaaagata gaggaactta
    26881 agggaatact tatgaaaaga gaatctaggc tacaatctac attagatgta gcagtaaata
    26941 gcatagtagt atttagcaaa gatggagaaa ttacatatgc aaataagagc tttagaaata
    27001 cttttggaga ctataaagaa caagataaat tgactgataa aataaaaaac ttcaatgatt
    27061 tgatagaaag cattcattat gtgtttgttc atgagaagaa tgcagagaaa cttattagta
    27121 caagcgataa taaagtttat caagctatat ttgcaccttt aattattgct tcacaaacag
    27181 aaggagtatt gtgtgtacta gaagataaga ctaagaaaaa ggagtacgaa cgcaaactta
    27241 ttgaagcaaa taagagaagt aaagattttt tagaaagtat tggagatggc atagtagtgc
    27301 ttgaaggtaa taacaaaata tatgttaata atgcatgtag ggaaattttt aaaaataatt
    27361 tagagagtat tgatttttca ttagtatgta aaagtgaaga aagtatagaa aaaagatatg
    27421 taatagatgg tgaagtaaag tatgtagaga tgagtttttc tcagtatact aatgctggta
    27481 ctaataaaac tattattgta atacgtgata caacctctcg aaaaatatct caaataaaac
    27541 ttgaggaaag tcaatcatca tattcaagat ttatagatat attacctgat ggcatatgct
    27601 tattaaaaga agatttaagt ataaactatg caaataagtc gtttttagat atgctagctt
    27661 ttacaaacat agatgatata aaagattcta atattaaact attaatgaat gcgaatactg
    27721 aagaaaaaat gaaatttacg gataatatgg ctaaagtttt aaatgaaaat agaagtatac
    27781 ttttactgga acatgaattg ataaatagtt atgatgatat agtagaagta gaattaagtg
    27841 cattaccttt tgctatatac aatactagat acataatgct tattataaaa gatttagtac
    27901 ataagaaata ttccgagcaa gcagaaaaag aactgcttga aagatttaaa acagataaaa
    27961 tcaaaacgga gttttttgca aatatgtctc atgaactaaa aactccacta aatgttatat
    28021 ctagttcaaa tcaactggta gattctttct atagaaatga aaagataaaa gattacaata
    28081 acaatattaa atctcatgtg gatttagtta gacaaagttc ttataggctt caaagattaa
    28141 taaataacat tatagattta acaaagatgg agtctgggtt ctatacacta aaacttgcga
    28201 aatacaatat tgtatctgta atagaagact tatttatgaa tatagaagag tatgcactta
    28261 gaaaagacat aaaaattctt tttgatacag accttgaaga aattaatgtt tatatagaca
    28321 aggttgaaat tgagagaatt atgttgaatc tattgtcaaa ctgtattaag tttactgata
    28381 atggaggctg gatatatgta agtattcatt ataaaataga taaagtaatc ataagtgtaa
    28441 aagacactgg agttggaata ccacaagata aattagagtt gatttttgaa gaattttcac
    28501 aagttgataa gactttatcc agaaatactg aaggaagtgg aatagggctt gctatagtta
    28561 agaatctagt aagtcttcat ggtggagata tagaagtagt aagtgaagtg aataaaggca
    28621 cagagttctt aatttcactt ccaatgaagg gatttagtag tgaacattac acagaagata
    28681 agagaatata taatattcaa gaaaaaataa aaatagaatt ttctgatata tattattaaa
    28741 aatgattatg agcaaaaata aaataaaaat actatttgtt taaatattta agttgtaaga
    28801 aataggctat cataaggtaa attattatga tagcctattt ttagctaggt tttatatcta
    28861 tatgtgagaa catataatct ctaaattacc ttcaaaacta aaatctccaa agtcgtttgg
    28921 cagtataaaa tgcataccct tttttaaatt atattctaca gaattgtgta taagttttcc
    28981 atttccatcc aacacactgt ataaagaaaa aggtgtattg tgtgtaaaat tacattttcc
    29041 aaaaacatct aatttataaa cactaaaaaa ttcgtttgac acaaatgttg tgcatttaaa
    29101 gtctgatgtt gatacgattt tatagtcagt atcgaaattt atatgaggaa cattcgtaac
    29161 atctattgat ttttgaacat gaagttcacg cttattacct gaattgtcag ttctatcata
    29221 atcatagact ctataagtag tatctgagtt ttgttgagtt tctaaaatca atgttccttt
    29281 gcatatagca tgtatagtgc cacttggaac atagaaaaag tctccctttt ttatattaac
    29341 ctttctaagt agtttgtccc attcattatt atttaccata tttacaaatt ctttatgaga
    29401 ttttgcatta tgacctatta taatttctgc atcatcagaa caatctatta cataccaaca
    29461 ctctgtctta cctaactctc cattttcatt ttttttagca tattcatcat ttggatgaac
    29521 ttgaactgat aaattatcat ttgcatccaa tatttttgta agtaaaggaa acttatcacc
    29581 aggtgtgttt ccaaataatt ctctattttt attccacaat tcagatagtt ttttaccttt
    29641 atattttcca ttttctatta agcaatctcc atttttatga gagcttatag cccaacattc
    29701 accagttgtt ggcgaatcta tttcataatt aaatttatct ttaagtgcag taccacccca
    29761 tattctatcc ataaaaatag gttttaaaaa taatggttcc ataatcctgt tcctcctatg
    29821 atattaaatt tatcctacaa ataattatat ataaatagat tataaaatca atagtaaaaa
    29881 agttttgtcc cttgaaatga cataaagtat aaggagttat taaataagat aaactatgat
    29941 atataatata aagttctaaa ttggagtgat aattatggag ttgtttaagg cagaaagcaa
    30001 aaaatataaa aaagaatttt taaaattatt ggagcaatgg gttagtatac cttcatttta
    30061 tgatagaaaa actgtatcta aagacatgcc ttttggaaaa ggagtatatg atgcattaaa
    30121 ctggtttgaa aatctaggta gagaaaacaa tttcaaagta aaaaatatag ataatcatgc
    30181 tgttcaaatt gaatatggaa atggtaaaga gtatgtagat atatttggac attgtgatgt
    30241 tgtaaatcca ggtgaaggat gggatagtga accatttaaa ctaaatatta taggtgataa
    30301 attagttgct agaggtgtat ctgataataa agggcctatg atagtgaatt ttttagcact
    30361 aaaaatgata aaggatttag atattaattt aaaaagaaag gttagattaa tagctggggg
    30421 aaatgaagag agtggattta aatgtataaa gcattattat agcaaagagc catatggtgt
    30481 atgtggattt actccagatg ctaaatttcc tgtattaaat ggagaaaaag gtggagcaat
    30541 aataaagtta atttcaaata tagacgataa atctttatat ataagtggtg gaatagagtt
    30601 taatacaata ccagataaag tttatataaa gaatgtagaa aaattgggta aagataatat
    30661 atgttttgat attaacaata tatcgataaa ttatgataat ggcaattata ttgtgtatgg
    30721 aaaaggtggt cattcatcta aacccgaaaa atcaataaat cctatattag ctacaattaa
    30781 acttttgtca gaaaatattg atgaaaaatg gacaaaagat ttatataagt tgataaatca
    30841 agataatata aatggaaact tatttggttt aaatattgag gggaaatgtg gaattttatc
    30901 aatggtgcca acaataataa atatagtaga tggaaaatta gaagtagttt taagcgttag
    30961 atatccagaa atattaacca ttgaagatat aataaaaaaa tttaatttgt atatggagca
    31021 aaataatatt aataaatttg agcttattgg ggaaaattta aagcaagcaa attatataga
    31081 tagaaattca aaacttgtaa gaagtttgca tgatatatat ataaagtatt ctggagattt
    31141 aaaaaatgat gttagagtaa ctagtgcagg aagttatgct tctgaaatga ataattcagt
    31201 aatatttggt tgtgaatttc ctgatggtag ctttggcaat gtccatagtg cgaatgaatt
    31261 tgctagctta gatagattta taactgcaat aggtatatat gcagaggcaa taattacatt
    31321 atgtaataaa atataaatac aaaatgtccc ttatatagac atattatata tacaattaaa
    31381 attttacttg atatataatt gaaatcaaag agaaggtgat acaatgataa ctaagaaaca
    31441 tgcaataata gtaaagagtt taagcaataa agatggatat atgacatcaa acgaattagc
    31501 tatcaaattg gatgtgtcta ctaaaactat taaaagatat atagcagatt taaatagtgt
    31561 tttaagcaaa tatgatttgg taatagcttc ttctagaggt ataggataca agttaagcgg
    31621 ttctaaaaac aatatagcca gagctgttaa agaagcaaat aaatatattg atggtttttt
    31681 agatgactct gaagagtcaa gaatgtcaaa tataatatgt atgcttatta atagaaatta
    31741 tatgagtata gaagcaatgg cagaagaatt aaatctaagt atagccgcta taaataaatt
    31801 gtctagtaag cttaaaagaa aacttgaaaa gtatgactta gttataaaat ctaaacctta
    31861 ctatggaagc tatatacatg gtgaagaaat taatataagg caattaatta ctgactatgc
    31921 aataaaatta gatgaaaaaa gtaaagtgaa ggtgttttta gatgacatta gtgaaaacga
    31981 tatacactgt atagaaagta ttttagaaaa gcacttaaga gaaaaagata caataatttc
    32041 agataaagat tttaatcttt tgctttcaaa aataatcgtt tctgtattta ggagtaagag
    32101 aggtcatagt aacaatataa acttaatgga tacaagttat agatttcata actactactt
    32161 tatagaaaat ctaatgaaag aaatatctga taaaattgga tttaaactta ttgaagatga
    32221 agtaatttat atttcaaatt attctggtgt aatagcctat aaaggtacac aaggaagaaa
    32281 aaacacaagt gaaattgagg aacgaataag tagtgttata agtagtgcac ttcaagatat
    32341 attccttatt tcaggtagtg attatacaaa agatgatgag tttatggttg caatctctga
    32401 ccatataaag agatttttaa atagagctag agctaatgta aaatcaaata atcctttact
    32461 tcatcaaata aaagagaagt ttcctatagc ttttaattta gccgtgtttt tatcaaataa
    32521 actagaaact gagtttaatt taaaacttga tgaagatgag cttggatata tagctatcca
    32581 ctttgctgct tcaaatgaaa gaatgaaaaa aaatactagt aagaaaattt gtatagtttg
    32641 tcattatggg ataggaacag gacaacttat ttctgaaaag ctaaaacaga atataagtga
    32701 tttaagtgtt gtaggtgttt atccagttag atatctcgat atggctataa gtcaagatgt
    32761 tgatttgata gtatctaccg ttgaattaaa aggatatgaa aaacctgtct tatatataga
    32821 aaatatattt gatgatagct taattgaaaa cgtaaacaaa gccttttatg aaaaggaaga
    32881 aagaagaaag ataataagca acatgtttga tgaaaaagct tttttcagta taaaggctaa
    32941 tactaaagaa gaggtcataa tttcactttc aaataaacta aaagaaagag attttataga
    33001 ggaaagttct ataaaaagta taatagatag agaaaatatt tcatcaactg aaataggaaa
    33061 tctagtagca ataccccaca caatagtgaa gggagataaa aaatctataa taggagttgg
    33121 aatacttgaa aatccaataa tttgggataa gcaagaggtt cagctagtat ttatggtatt
    33181 ttttaatact aaagaaaaac ataatttctc gatatttaaa tacctttata attttataaa
    33241 agatgaaggc ggagtaagag gaattattaa aatatgtgac tttaataaat taatggcact
    33301 gataggtaat taaggaggaa attaataatg ggaacaaaca tatttaacaa agaatatgta
    33361 tttttaaatg ttgatgctaa gtcaaaggtt gaagttttaa aatttatatc aaaaaaagct
    33421 aaagacttaa acttggcaga agatgagagc ttagtatatg aaggtttaat ggctagagaa
    33481 gaacaattta ctacaaattt aggagaatct atagcaatac ctcacactaa aaatgatgca
    33541 attgaaaatc cagcagtagt agtattgaag tttaatgaag atgttgtttg gaatgaaggt
    33601 gaggataagg ttaaattagc aataagctta cttatgccag gaaaaagtaa agagaatatt
    33661 catcttaaat tattatcatc tctttcaaga aaattaataa ataaagaatt taaagattct
    33721 cttttaaaaa gtgataatgt tgaagaaata tctaacttaa taaatgaagc tttaggttta
    33781 taattaaaca ctaaggttat aaaataaaaa aataattaac taaaaatagg aggaatttga
    33841 aatgaataaa aaattagtag cattatgtgc ttgtccaatg ggactagctc acactttcat
    33901 ggcagcagaa gcaatagagc aagcagcaaa ggcattaggt tatgaagcaa aagttgaaac
    33961 tcaaggtgct gatggtgtac aaaatgagtt aacaagagat gatatattag gagcaactat
    34021 gataatacat gcagtagcaa taacaccaga aggtatggaa agatttgatg gttgtgaagt
    34081 ttatgaagtt gaattacaag aagctataaa aaatgcagaa ggtgttataa aagaaataga
    34141 agaagattta ggaatataat aaatttattg tggaggaaat agaatggcaa ttaagaaaaa
    34201 agttataaac agttcaggtg cttctacaac aggaggaaat aatgtaggaa aatctactcc
    34261 atctagtcca actcaatcaa agggaaatgg aaaatggaaa gaaataagta aacatataat
    34321 gacaggtata tcatatatga taccagtttt agtaatgggt ggacttatag gggccttatc
    34381 tcaattaata ccatatgcta tattaggact tgacccatct gtaggtatag ttgatgctat
    34441 gaactcagga gaatttacag ggttcaagct tagtctttta aatatagcac aattaatgtc
    34501 aaatttcgga tttactttgt ttggatttgc gataccactg tttgcagcat tttgtgcaaa
    34561 ctctataggt ggaaaaacag ctttaattgc aggatttata ggtggatata tagctaataa
    34621 acctgtaggt gtaccacaat tcgttgatgg acaatggact gaagttgttc cagttgcatc
    34681 aggattttta ggtgcaatac taatagcatt tataatagga tattttgtaa aatggttaaa
    34741 taaatctata aaagtttctc ataactggtt agcttttaaa acaacatttt taataccatt
    34801 aatagcgtca ttagcttgta tggtattgat gatatttata ataactccat ttggtggatt
    34861 aattaatgaa agtatgaaaa acttcttaac agcagcagga gcagctggag aatatgtata
    34921 tgcaacagct ttggcagcag ctacagcatt cgacttagga ggaccaataa ataaagcagc
    34981 aggattcgtt gcacttggtt taactacaga gaatgtactt ccaataacag caagaacaat
    35041 agctatagtt gttcctccaa ttggattagg gttaacaaca ttattagata aaagattagt
    35101 aggaagaaga gtatatgata gacaattcta tcaagcagga aaaacttcta tattcttatc
    35161 atttatgggt atatctgaag gagcaatacc atttgcactt gagagaccag gttttgttat
    35221 acctttaaac atagttggaa gtgtaatagg agctattaca ggtataattc taggagcaat
    35281 tcaatggttc ccagagtcag ctatatgggc atggcctcta gtagataact tatttggata
    35341 tataataggt atagcagttg gtgctatatt catagcagta ggaaatatat tctatagaaa
    35401 taaattaata aaagatggta aacttgttgt agattatatc gactagtatt taatttttac
    35461 tatctataaa taactttggc tggtaatatg gttttaatca atattaccag ccttacctat
    35521 atgattaatt aaaggcggtg gagataagat atggataaga tagaaaaagt aagagagtat
    35581 tttagagaat atgatataga tggatttctt ataaatagtc ctacaaacaa gttttatgtt
    35641 ggaaatttat ttagctcttc aggttatgtt tttataacga aagaatcaca atatataata
    35701 gtagatttta gatattttga agaaattaaa agaaaatcta gtttgtttaa tgtagtatta
    35761 atggacaaaa ctagaactca ttttgatata attaatgata tttgtagaga gcagaatata
    35821 aaggaaattg gatttgaggg aaatgaagta tcttttgatt tatatagaag tatgagtaat
    35881 aagttaagtg caaccttaaa atcagttgat ttatctacat taagggaaac aaaaaatgaa
    35941 gacgaaataa aatatataaa aaaagcttgt gaaatagttg atgctacatt ttatcatata
    36001 gtagacttta taaaggttgg tatgactgaa aagcaagttg aaaatgaaat tgttagaatt
    36061 ataaaagatt taggtggtca aaaagaatct ttcgatacaa tagttgcatc tgggcttaga
    36121 ggagcattac ctcatggaaa agcaagtgaa aaagttatag agtatggaga ttttgttacc
    36181 tttgactttg gtgctaagta taataattat tgttcagata ttaccagaac catttgtatg
    36241 ggtactataa ataaagagtt agaagaaata tataatatag taagaaaagc taatgaagag
    36301 tgtataaggg ttttaagacc gggaatgact actggagaga tagataaagt tgcaagagac
    36361 ataattggtt catatggata tgctggtaat tttggtcata atctgggtca tggtgtagga
    36421 attatggttc atgaatatcc tgcattagct cctgaatcaa atgaagtatt aaaagaagga
    36481 atgattgtaa ctatagagcc tggtatatat gttccaagtc ttggaggcgt aagaatagaa
    36541 gatgatgtac ttataacaca agatggatgt atgagattga ctacatctac taaggattta
    36601 atagttgtaa gctaaaaata aattagataa atattttata acaataagaa aagaagaggt
    36661 aaatttaaat gtataatttt gatgataaac cagatagagt aagtgaaaag tgtagaaaat
    36721 gggatttaaa tattataaga gataaatttg gagatattag agaagatttt ataccaatgt
    36781 ggattgctga tatggatttt aaaataccaa cagaaataga aaacaaattt attgaagctg
    36841 taagaagagg tgtatttgga tatacatact gttatgatga attttatgat tcagttattg
    36901 gttggcaaaa aaatatgcat gaggtaaatg tagaaaaaga atggattaca ttaacttatg
    36961 gaactgtatc aacacttcat tatgtagtac aagctttttg taagaaaggt gatagtataa
    37021 tattaaatac accagtttat gacccctttg aatcatcagc aaaaaaacaa ggtgtaaatg
    37081 taatttgtaa tacattagat gttgtaaatg atagatatta tataaatttt gataaattag
    37141 aagttcaaat taaagaaaat aagcctaaat taatgatgtt ttgtacacca cataatccat
    37201 ctggaaggat atggacaatt gaagaaatga caagggtagc aactatatgt aaagaaaata
    37261 atgttatttt ggttgcagat gaagtacatg cagagcatat tcattatggt acatttaatt
    37321 caatacttaa gattggaaaa gagcttttag aaaatgttat tctattgaca tcaccaaata
    37381 aaggatttaa tcttggtgga ttaaagactt cttattcaat agttataaat aaggatataa
    37441 gggacaaatt tagaaataaa ttaaagcaaa attctataac ttctccaaat gtgtttggaa
    37501 taataggatt gataaccgct tataatgaat gtcatgagtg gttaagtggt gtaaatgaat
    37561 atataaaatc aaattatgaa cttttagaaa cttgggtaaa taaatataat aagataaaat
    37621 tgatgaaaat ggaatcatct tacttagctt ggatggatat aagtggatta ggtattagtg
    37681 caagtgagtt tacagataaa ttggctatag atacaggagt attattagaa gatgggagtc
    37741 attttgtaaa agatggtgag aagtatgtta gaataaattt aggaactcaa aaggaaaatg
    37801 taattgaagc tttaaataga atggatttat ttttaaagtc tttataaaaa tttggttgaa
    37861 ttagtatttt atataaattt aaactattaa tatggtatat acataagtag aatttgtttt
    37921 agattactta agtatatacc atattttata taaaaattaa atttgcatta gtcatgtgat
    37981 aactatttaa attcatatgt attttgtatg tataatagat ataattatta tttaaactta
    38041 ttgtttattt aatttttcaa tagaaaaaga tttatctgta agtttaaaat tatcttttat
    38101 acccttagtt aagtatactt tcttatcctt agttatgaat atagcatcta cattatcaat
    38161 tttattaatt aaattcatac ctttttcaag accaagacca aatgtagaag tggataaggc
    38221 atcacaatta atagatttat cagagattat tgtaacacta cttaaattgt tttcaaaagg
    38281 ataccctgta aatggattta acatatgatg atatattttt ccgttttttt cgataaatct
    38341 ttcataaatt ccagaagtaa caacagactt atttgtagtt tctatgtttc ctatggattc
    38401 accattttta ctagttgggt cttgaatacc tattttaaaa ggtttatcat ttttaccatt
    38461 ttctaaagta aatatatttc ctcctaagtt tactaaacct ttttttacgt cctctgattt
    38521 taaataggct acaattttat cagcagcata tcctttagct atggcaccta aatcaatttt
    38581 catattttct ttggttaatt ttatagattt atttttttca tccaatatga tgttcttata
    38641 atcaataaga ggcagaagtt tttgtatctc agaatcactt ggaactttag ctttatctgt
    38701 tccaatagcc cataaatttg ataatggacc aattgttatg tcaaaatatc catctgataa
    38761 tttggaatat tgtatagctt cttttacgac gaaaaatgta tcatcagaaa ctctgacaaa
    38821 ttttttacca gcattatcat ttattttaga aacatcactt cctggtatat gagtgctcat
    38881 tttgttgtca atatatctta aaattgaatc acattcattt aagattttat cacttttgga
    38941 ttcttttaca ttaaatacag taacttcgtt tactgtacca aggtagtagc tagttttact
    39001 atatttagta ttctggcttg aactcctaaa aaatgaaaat aaaattaatg ctaaaatcaa
    39061 tatcacaaaa ataaatgtga tttttttctt attcatggta tattcctcct atgaaattgt
    39121 gttattattt tattataaca taatttcata ggaggacaaa aaatgaagaa aaaagacatt
    39181 cttcttattt taggcatttt ggttgttatt acagcatgtt atgggataat aaatgttata
    39241 aattctaaaa atgctggaaa tattgagatt tatgtagata ataaattgta taaaactgtt
    39301 tcaataaatg ccaaagaaga atttaaaata gagaatagag gggggtataa catagtaaag
    39361 attcatgata aaggggttga gatagtagat gcttcatgtc ctgataaggt ttgcgtacat
    39421 actggattta taaacaagcc aagtcaaagc atagtttgta tacctaatag agtgagcata
    39481 aaaataaata caaatgaaaa gaatgataat caagaagata taatttctaa ataaaataat
    39541 aaaaataatt gaaaggaatt ggtgataatt atggttaact taggaaacga ttgggatgaa
    39601 ttattgaaag aagaatttga aaaagattac tacttaaact taagaaaatt tcttatagaa
    39661 gaatataaaa cacgccaaat tttcccaaat atgcacaata tatatgaagc tttaaaacac
    39721 acttcataca aagacacaaa agtcttaata ttaggacaag acccttatca tggagataat
    39781 caagctcatg gtttagcttt ttcagttcaa ccacaagtga aaactccacc atctttatta
    39841 aatatgtata aagaattaaa agatgattta ggttgtttta tacctaataa tggatattta
    39901 atgccttggg cagaccaagg agtgttactt ttaaatactg ctcttactgt tagagcgcat
    39961 gaagctaatt ctcataagaa caaaggatgg gaaattttca ctgatagagt aatatctatt
    40021 ttaagtgagc gtgaagaccc agttattttt gtactatggg gaagtaatgc acgtaaaaaa
    40081 gtagagttga ttgatacaag taaacattat attttggaag cacctcatcc aagcccattg
    40141 tcagcaagta aaggcttttt tggatgtaaa cacttctcta agataaatga aattttgaaa
    40201 aagctaggaa aagaacctat taattggcag atagaaaata tataaaagta aaaggtaaca
    40261 aaatgataac aaaacaacaa taaacaatga cattgttgta actaatagaa atatgcttaa
    40321 atagttgaaa atactatgta tgcatatttc tatttttttg tcaagttgac aactcttgaa
    40381 aaaatagtta caatttagtt acacaaaaaa cacaaataaa aaaagaaact tacaaagcag
    40441 aattttatga agcaaaatat atagtgtaaa aaatcttagg gaggaaattt tatatgaatt
    40501 ttaaaaaatt gagtaatgct aaagtctcgg taatggcagt tgttttatca gttggaatat
    40561 tatcgggata ctctgcgctt aataaacaag taacattagt agtaagggga gaagaaagaa
    40621 ctatatcaac atttagttct aatgtaggag accttttaga atctcaaaac attagctatg
    40681 atgcaaatga tatagtaact ttagatgaaa atacaaagtt atctaatgga gataaaatag
    40741 aagtaattga tgtaaaggaa aaaacagttg tagaaactaa agacattcca tttgaagtta
    40801 cagttgttga agatggctct ttattaaagg gtgattctaa ggttaaagaa gaaggaaagt
    40861 ctggtaaaag tgaattaata tataaagaaa cttatcacaa tggaaagaaa gtagaaaagg
    40921 aatttgtgaa aaaggttgtt aaagctgagc cagtaaataa ggttgtaagc aaagggacaa
    40981 aggtagaaat gcaagtagcc tcatcaaggg gagaaagttc aagaagaatg gcttcatcat
    41041 catctagtag cagtagtagt aacaatggta aaaatatgag agtggtagca actgcatata
    41101 ctggtcacag tataactgca acaggaacaa aacctaagtg gggaacaata gctgtagacc
    41161 ctaaggttat accatatgga actaaagttt atatacctca atttgacatg gtgtttactg
    41221 cagaagactg tggtggagca ataaaaggaa ataaaattga tatctacatg aatgattcaa
    41281 aaacagttta taactgggga agaaaaacta tagatatacg tatattaaaa tagttaaata
    41341 atttatattt ttactggaaa ttatattttg attatataga gaagaaactc tttatagatt
    41401 ctaaaaatat aatttccagt tttttatttt ggatatgtaa taaaacaggt aaattttaac
    41461 catgtataga taaaagctat ttaaattata atttactatc atataaatct ataaaaattg
    41521 ttgcaaagag tcaaaatata tgatattata gatttcgttg agaaggattt cattatggga
    41581 gtggatgggt gccggtgtgc cctctagtct tcaaaactag tatgaggggt taagagcctc
    41641 ttaggtgggt tcgattccca cgcattcccg ccaatatgta aaaggtatct tttaattaaa
    41701 agataccttt ttaaatttgt tttaagataa tttagtttta atgatatata atattttgta
    41761 ttatataatg taaattttat aatactatta ttgttcagat aaaagtctag gagagtgaaa
    41821 agatggaaaa taattttaca acgagaacta gttttctagt tggagatgat gggatagaaa
    41881 aacttaataa ttcaaatata atagtatttg gagttggagg agttggtagt tttactgttg
    41941 aagctttagc aagagctgga gtaggcaata ttactattgt agattttgat gatgtagata
    42001 taaccaatat aaatagacaa ataccagccc tacattcaac tgtaggaaga tacaaagttg
    42061 atgtcatgga agaaagaata ttagatataa atcctaatat caatataaaa aaaataagaa
    42121 gtctttataa taaagatact agtgacgaaa tactaactga aagatatgat tatgttgtgg
    42181 atgcgataga catggtaagt tccaaaatac atctaattga aacttgtgaa aaaaaaggat
    42241 tgaaaataat aagttctatg ggtatgggaa ataaattaga cccaactaaa atagtcgtta
    42301 cagatataca caaaacaagt acttgtcctc tagctaaagt tatgaggaaa gaacttaggg
    42361 atagaggtat caaaaagtta aaagtagtat attctactga acaaccaata gaacttaaga
    42421 agaaagtaat gaatggtaga aaagtaacac ctggtagtgt atcatttgtc ccatctgtag
    42481 gaggtttaat aatcgcatct gtaatagtaa atgaactatt aggacaataa gttttaaata
    42541 ttttaattta taaattttat atacaaattt gaaggctaga aggatgaata taaagcaatt
    42601 ttatattcat acttttagcc tagttatttt atattacctt attttatgta gttgtagctt
    42661 tattttttag attatgtatc tatttcataa ttatattttg taaatataat ttctccatca
    42721 ctataaaaaa caatatctcc tattctgtct gttctataaa ttgatacatg gttttgtttt
    42781 agattattaa taacctccct atgtggatga ccatattgat ttttatatcc acatgatatt
    42841 gcagctatat ctggactaat tttttttata aattctaaag atgaagaaga attacttcca
    42901 tgatgaccta tttttataaa attaatatta tttaatttaa aagaatgtaa aatttctttt
    42961 tcattttctt cttcagcatc acccataaat aaaaaagaat tatcattaaa agttaatttg
    43021 aaaactatag aatttaaatt agattcttct tgtatatatg atggacttaa tacatatata
    43081 tttatattgt tatctatgtt taaaacatca tttttataga gatgctgaat agataagttt
    43141 ttatccgtac aagaatttat tagattttga taagcctcac tatcagttga ttgttcaggc
    43201 atatatatgg agtttacatt aaattttttt ataatattat caagacttcc tatgtggtct
    43261 gaatctggat gagttgctat tataatatca atagttttta ttcttttttg tctaagataa
    43321 ctaataatta tattttcgct atcttcatca cctccatcaa ttaatatatt cttatttgtg
    43381 ggtgtttgaa ctaaaatact atcaccttgt ccaacatcaa tcatatgtat agatagtaga
    43441 gattttttgt cacagccgat taaaagtgat attataataa gtattgataa aaaaatttta
    43501 tttctcaata aaaaatcact ccattcatta catgtttata taaatttatg atgggtaata
    43561 taagatatat atgacttatt atattttata ttttaaacaa tataaatgaa attaatacca
    43621 taataaaatt ggagtttttt atatatacaa aataaaattt ttaaaattaa gcaataaaaa
    43681 aggtaggagg attttatgtt tttcaaagat attgaactaa attcaaaaaa agagttagac
    43741 ccatattttg atttagtaga ttatgaagct tgtgagtact gttttagtac tttatatatg
    43801 tggcaacatg tttataagac aggatattat ataggtgaag attttgccgt tttagttggg
    43861 gaatacgaag gagatagctt ctcaatatta ccacttgcta aaaaagataa acttccagaa
    43921 gttgtagatt ttgtccttga atatttttct aaaaataata aaaaaatata cttaagaggt
    43981 attactactg aagtagtaga gtttttaaaa gaaaaatatc caggtagatt tgagtatata
    44041 gaagaaagag atttatttga ctatatttat gatgcagaaa gtttaagaac tctagctggt
    44101 aaaaagaatc aaaagaagag aaaccatata aactatttct taaaagagta tgcaggtaga
    44161 tatgaagcta aattattaga taaagaaaac tttgatgagt gtttagtact aatgaaggaa
    44221 tgggaaagta ataaggaaga aaataatgaa tttgatgaaa gtatggatga tgaattaata
    44281 ggtatcaaaa agatatttaa ccattatgac atattaaaag ataaggtaaa agtgtttggt
    44341 gtttatgtag atggaaaatt agaagctttt agtataggag agcttttaaa tccaaatatg
    44401 gcattgattc atatagaaaa agctaatcct gatataagag gtctgtatcc atttataaat
    44461 caacaatttt tggtaagtga atttaaggac gttgagtttg taaatagaga agaagattta
    44521 ggtattgaag gattaagaaa agctaaactt tcttatcatc cttgcagatt tgttgaaaag
    44581 tacagtgtta gggaggctta atagactata tggagattag gtatgctaaa gaagaagaga
    44641 tagaaagtat aaaagagatt tggagttatt gttttaacga tacggagagt tttatgaagt
    44701 actattttaa tgataaatat aaatctgaaa atactgtagt agctttagat gaaggaaaaa
    44761 ttatttcttc tcttcagcta aatcagtata agttattact aaatagcaag gtatataata
    44821 catcatatgt agtaggagtt tctacacttc cagagggaag aggagctgga tatatgaaca
    44881 aagtaatgaa atttacttta aacgaattgt ataaaaaagg gcaattagtt tctatattga
    44941 tgcctattga ctatagactt tatagaagat ttggatatga gcattgttac gaccagattg
    45001 aatatactat taacacagat gatttaaaaa attttaagtc aagtggaaaa atgataaagt
    45061 ctaatttatc acaaattgat gatttgatac aaatagatag aactttttta aatgaggtta
    45121 atggtaatgt gttaaaagat gaacattatt atgaaaactt atttaaagag attcaaagtg
    45181 aagatggatt tttatacatt catgaaggaa atgaaaaaga tggatatata gtttattttc
    45241 ttcaggaaga taaaatgttt gtcagagagt tattttataa aaatatagat gcccttaaat
    45301 caatgcttaa atttatatat aatcacaata ctcaatgtaa gatagttact atatctactc
    45361 ctacaataga taagataaga tttatattag acaaccctaa agatagtgat ataaaaataa
    45421 aaccttttat gatgggaaga gttataaatg taaagaagtt tattgaagat atagatattg
    45481 agaatgatat taatagctca tttaatttat taatagaaga caagtttata gatgaaaata
    45541 atggtctatt taaaatttct atacagaata agaaggtatc tgtagagcag ttagataaaa
    45601 aaggtgcaga aaagcctcaa gaagattttg atattaaatt agatataaat accttaacac
    45661 agttatcatt ttcttatata gatgtaaatg aagctatttt cttaaatgat ataaaagatg
    45721 tttcagaaga aacactagaa acacttaatt gtattttttc taaaaaaaat aactatataa
    45781 atgaatatat ataggtagag tacgttaaaa gattttaaaa atcttttgac gtattttttt
    45841 gtttagataa caatttatct tgtttaaaaa ttttctattt gaaaataatc taaataatat
    45901 acttttatat gggagtgatt ataattcaaa taagaagacc attattaatt atattaatgt
    45961 ttgtggtagc tatatcattt atcattacaa ataacacaaa aaacgacgaa gaacttaatg
    46021 ataagataat aactatacaa ggagttgtca aaggaaaaat tgaaaagaaa agatacaatc
    46081 agtacaaggt aggggttttt ctaataaatg attatacaaa aaataaaaat ttgaagattg
    46141 gtcagaaagt taatattaca ggtaaattca aaagtttaga taaaatgaag tatgatgatt
    46201 ttgattatgg aaggtatata aaaagtactg gatataaagg tatagtgtat ataaataact
    46261 ataaaattat tgataaaaat aaactttact ctttaatagg ggaaataaag ttttatatta
    46321 gtaaaactta taggtactta tataagaaaa actcagattt tataaattct atactattag
    46381 cagaagttga aaatttgact gaggaacaaa aagaaatttt tactagaact ggaactagtc
    46441 atgtaatatc tatatcaggt cttcatacag gaatattatg tgtaattata tcctttctat
    46501 taagaggtat aaataaattg tataaattat taatactgtc gatttttata actttatatt
    46561 gtataatggt aggtgcgtct ccatccataa ttaggtctat agcatttgtt atgatttttt
    46621 atttatcaat atttattgat agaaagaaag atggaatatc ggcattgtct ctaattggga
    46681 taattttaat tatgaataac ccctatgtta tatataatgt aagttttcaa ttgtcttttt
    46741 tagctacact ttctatatta atattctata ataaaataaa tagtattata aaattaagta
    46801 tggtatcatt gacaatatca tcaaatatat taactttacc tataatttat tatacattta
    46861 aaggtatacc attgctttca attataggaa atttaattat agtaccattt gtgggagtaa
    46921 taatgtattt aagtattgca agtttaatcg tatttaaagt aagtgtagta atagctaaaa
    46981 ttatatcttt ttttaatagt acatttatag aaagcatatt ttttttacta gaaaaaatca
    47041 gcaatttaag ttttgcatac attaatatag aaaatcctaa attttatatt gttgttattt
    47101 attacatagg agtgtttttt tacatatttt acatagaagg aaaagagata aaggagcaag
    47161 agaatgaatt acaaggatat tataaggaat gtaaaagaga aaaactttga aaaaatgtat
    47221 cttttttatg gaagagagta ttatttaatt gagaatgcaa taaaagcatt taaagatagt
    47281 ctaaacgagg gaatgcttga ttttaactta gatataatag atgggaagga aatagtctta
    47341 aatcagctta taagctctat agaaacactt ccatttatgg atgatagaaa gatagtaata
    47401 ataaaagact ttgaactatt aaaaggaaag aaaaagaatt ttacagatag tgatgagaaa
    47461 tacttaatag agcatttaga caatattcca gacaccacaa ctatagtttt tgttgtatat
    47521 ggagatgtag acaaaagaaa atcattagtt aagaaaatag gaaacaatgg aattgttttt
    47581 gattgtgata agctttctga tatggatttg tttaaatgga taaaaaaatc ttttgcttta
    47641 aatgatgtta taatagataa ttctcaaatc atgtatttta ttgaacaaga aggatacaga
    47701 gataagagta gtgaaaagac attatctgat ttagaaaatg aaataaataa aataagttca
    47761 tttgttggta aagggaataa tgtaaccaat gatgtaattg ataaattatc tcaaaaaaaa
    47821 gttgagaatg atatattcaa attaatcgat tatattggag aacaaaatgc ttctaatgca
    47881 atgaaaatat taaatgatat gatacaagaa ggcgaatctg tattaggtat attttctatg
    47941 atagcaagac aatttaaaat aattatgcaa gtaagacagt tacaacttga tggatattca
    48001 acaaaactta tagctgataa attaaaaatg catcaatttg ttgtaggaaa agcattaaag
    48061 caaactaaaa atttttctga tgatataatt gtggaaatat taaactatat attagaaagt
    48121 gattataaaa taaagacagg tcttataaga gatactttag cagttgaaat gttggttagt
    48181 agatactgta aaagagaagc aatttaaaaa atctatatat taataaaaaa taaatagcaa
    48241 gatatgttat agttcagagt agatgtaagc taaattaagt ttgatataca atcaactata
    48301 atatgtctaa ctatttattt tttattgtat aaatttacaa aataaaaaac ccctacatag
    48361 gggttattat atataagaaa tataaactgg taattaagcg ttcataccgt ttaatttttg
    48421 agctaattta gctacttttc tagctgcagc attcttatgt atagttcctt tagaagctac
    48481 ttggtatatt cttttttgag cgtattggaa cttagcaaca gcatcctctc tgtttccagc
    48541 tgcaacagca tcttcgaatc ttcttattgc agtttttatt tgagattttc taactctatt
    48601 taaagcagtt ttcttttcga taacacttat tcttttctta gctgatttta tatttgccac
    48661 cgtgttcacc tccctgtatt tttttatcat attcatcgtc aacatattag attttaacag
    48721 aaataaatct aaaaatcaag gattattatt tatatatttt aataatgttt tttattttga
    48781 ttttttagac tgtaaattgt gtataaataa tttgcaatat cttgttttta aattggtata
    48841 ttttgtgttt taaatatttt gacatatata aattaatatt ttatttttgt aacaaatatt
    48901 ttgagataat acaaactatt aacatacatt ttgatagtat ttccaataat tataagataa
    48961 tacaagaaat tactcatttt tgtaaattta atgaaaaatt ataaaaatat aaatttatat
    49021 gcttaattaa gataattttt ttcattagta tgtatgatag atgcatcaaa caatataact
    49081 aatatgttag aaggttatat gtaattaatg tcagtgttta tatagaatag catttgtagc
    49141 atttattata gttgtaatta ctatttatat catagacttg aatagtctaa aaaaatagac
    49201 tataatattt ttatagacta aagaaagggc tgataagatg gacatagcaa aactaatttt
    49261 aaatcctgca aggcttcgta ttttacaata tattcgactt tatggcagtg ttcgtacatc
    49321 tgatattgta aagtatttaa atgatattcc tcgtgcaaca gtttatcacc atgtaaaaat
    49381 tttagaagag aacaatatga ttgaagtaat taaagaaaat cgtgtgcgtg gtactattga
    49441 aaaggtttat gcactaaagg aatatacaac atctatggaa ggagagacct tcgttgcact
    49501 ttctacagca ttttatgtag gtctgatgca ggaaatgaat gaatacttta gcagaaaaga
    49561 gcaagaccat aaaaaggata atgtattttt ctcttcagca ttactatata tgagtgataa
    49621 tgaatatgaa aatcttctta aaagtatagc tgatttattg aaaccatata tagaacaaaa
    49681 acctaaatca aatctaaaac ttagaaaact ttcaattata tcttctccac ctgtagctga
    49741 taatgataaa acaaaataac atgcaaccca tttttataaa aggaggttat atatgaaatt
    49801 tcatgagttt ggaaataaaa acagaccaca tattatgttg attcatgggg gagggaatgc
    49861 atggtggaac tatttgcgac aagcagaagt tttgtctaac aaatatcatg tgatacttcc
    49921 tacattggat ggtcatggag aagaatatga aacaacatac atttctacag aggatacagc
    49981 agataagttg atatcatata tagatgaaaa ttgcagtgga catcttttcg ctttgtgtgg
    50041 ggtatcactt ggtggtcaaa ttgtcatgga acttttatct cgaaaaccta atattactaa
    50101 aaaagcaatt attgatggta gtatttgcta cccaagacct cttatggcaa ggttttgtat
    50161 tgctggtatt cgattttttg gaggactttt gtttagtgag aaggcttgtc gctttcaaat
    50221 tgctatgatg ccaaaattgt tacctgaaaa tatgcaatat ccagataaaa taaaagcgta
    50281 ttatatgaca gatatgccac atgtaagaaa agaaacattc tataatatgt atcgtactta
    50341 catgatgaac tatacactta aagagaatgt taaaaaaacc acagcacaag taatgtactg
    50401 gtatggagaa aaagaaatga agtgtgtcaa aaaatctgca aaactgtttc agtcttatgt
    50461 gccctcttgt gagatttatg aagctaagag ctataatcat gggtatttat cactttatct
    50521 tccaaatgaa tggttggaaa ttgcagaacc atttttccaa aaggaataaa ggtgttaggt
    50581 gattattgta taattattgc tgttttttta tatagtaaat aaattaggta taaatataaa
    50641 aaattatttt agttaatata ttagtgaaag cttaatagga aaattataaa tagattaaag
    50701 gtagcaccta tataaatagt tgctaccttt ttctgtttgt aaataaatga tagataagaa
    50761 ggtttactga caaatcactg actaaaccca attttcttac attgaaagcc ttaattttac
    50821 ttgttttaaa taaatttaca atttcttgtt ataaaatact aaattttgtt aacaattata
    50881 attagcattt aatttatact ggaggtttat atgattagtg taagaacaga tttagcttta
    50941 gaagctagtg aaatgtgtga aaagtctcaa gaaggaagta gtattcctgg tgtaaaaata
    51001 gaaactaaag aattagaaaa ttgcattgta actaaagttg aagtaataga caggcaaggc
    51061 gcagagataa tgaataaaga tataggaaag tatataactc tggaaagtaa tcttatgaag
    51121 tttgatgatg atgagtcaag agaagaaatg ataagttatt taaaagagga gttagtagat
    51181 atatttggcc aagacaaaaa taaaaaaacc ctggtaattg gtcttggaaa tagaaatatt
    51241 acttctgatg cgttaggacc aaagagtgta tcaaaaacac ttgtaactag acatcttttt
    51301 aaaaattata ataaagacta tgatgatgat ttcactgagg tatcagcttt aagcccagga
    51361 gttatgggtg ttactggaat agaaactagt gaaatagtaa aatcattggt tgagaaggtt
    51421 aagccagata gagtagtagc aatagatgca ttggcttcaa gaaaaatgga aagagtaaac
    51481 tctactatac agatatcaac agcaggaata tcacctggtg gaggtgttgg caatactaga
    51541 aaatctctaa ctaaagaaac tttaggcgtg gatgttattg caataggcgt tccaacggtg
    51601 gttgatgcag caactcttac aatagatgtc ttagatatgg caatagacaa tttaatagct
    51661 caatcagaag aaacagaaag tttttatgaa atgttgaaaa aacttaaaga agaagaaaaa
    51721 tatcatctaa taaaagattc gttagaccca tatgacaaga acttaatagt aacaccaaag
    51781 gatatagatg atacaatcga aaatctatct ataataataa gtgaaggctt aaataggtct
    51841 ttacatccag gtagattggt ataaaataag gaggagcaat tatgtttaaa aaatgcatta
    51901 aagtagtaac cttgactttt atattagtat gcattttacc aggaaaatca ttagctttga
    51961 atcaagatga ttttttaaag tttttagtaa attcatctta tccagaagct aaagtcgaag
    52021 gaaatgatac agaaaataaa aagaataata aaaataaaga aacaagtaag gaaaataagg
    52081 aagaaagtaa agaaggaaac actaaatcta aagatgcaag taaagttgat aataaaaaag
    52141 agagtgaaaa agaatatata aaactttatg ttggtaaaga aaatgttcca gatattgagt
    52201 caaaaaattc agacacaact gaaactaaca caacatctag ttcagattat aaggatgatt
    52261 taagagtaac caaagaaaat ccaagaattt tgatatatca tactcatgga tgtgagactt
    52321 attcaaattc acctgatgga aattatcatt caagagataa gaaaaattca gtaatggaag
    52381 taggaagtgc attaactagt gctttagata gcaaaggatg gggtgtagtc catactacta
    52441 aataccatga ctatccatct tataataact cttatgcaag tagcttaaaa acaatacaaa
    52501 gtatattacc taaatataac tcagtggata tagcgataga cttacataga gatgctaggg
    52561 atttaactaa tccagccact aaggaaaaag accatttaaa atatacaact atgataaatg
    52621 gagagagagt atcaaagttc ttctttgttg taggaggtaa aaatacaaat agaaaacaac
    52681 ttagagcttt agcagaagat ataactgctt ttgctgagaa aaagtatcct ggtctagtat
    52741 ctccaatagt agaaaaagac tatgctagat tcaatcagtt tgcagttaag aatcatatgt
    52801 tagtagaaat agggaataac gcaacaagtg tagaagaatc taaggctact acaaagtatt
    52861 tagccgagat tttggatgaa tattttaaac aaaaaaatta gagctttaag ttataattag
    52921 gagcatgcta aatgagccga ttagaaaaaa atatagaaag taaaagtaaa ctaagaaaat
    52981 acaagtatat tatgagaatc ttatttttga ttactatgat tatatgtaca tcagtttgtg
    53041 tatttatagt ggacagtaat gcaaaaagta tgctaggaat gaaacaatat gattttccaa
    53101 gtattaaatt tgatataaca aaatttgatt ttgacatacc aaattttgat atacatgaaa
    53161 tcataaaaaa atttaataag tagtaataag tgaataaggt ttattgatta aaataagcct
    53221 tattttagtt atatattttt aatgtataaa ataaaaattc attaactgta ttttatagga
    53281 tttactttaa gtttatgata ttatataata tttagtgtta gacttgataa tccacatata
    53341 atgtggataa ttttgtttag tgccaattag tttatattca aaaattttaa atttggtata
    53401 taaagagttt ttagataatg taaaataata actataagaa taatcaagag gagggaattt
    53461 taaggtggac aataaacaaa gtagaactag aaattttagt ataattgcac atatagacca
    53521 tggaaagtct accttagctg atagattaat acaacaaact gggcttgtta gtgaaagaga
    53581 catgaaaagt caattacttg acaatatgga ccttgaaaga gaaagaggaa tcactataaa
    53641 gcttcaaaac ataagattaa tgtataaagc gaaggatgga aatgaatatt atttaaatct
    53701 tatagataca cctggacatg tagactttaa ctatgaggta tcaagaagtt tagctgcatg
    53761 tgaaggagca ctattagtag ttgatgcagc tcaaggtgtt gaggcacaaa ctttagccaa
    53821 tgtttatctt gctatagacc aagatttaga aatattacca ataataaata aaatagattt
    53881 accaagtgca agaccagagg aagtaaaaaa tgaaatagaa gatttaatag ggcttgattc
    53941 aagtgaagct cctcttattt cagctaaaac tggtttaaac atagaagatg ttttagaaga
    54001 tattgtaaaa aatgttcctc cacctaaagg agataatgaa gctccattaa aggcattaat
    54061 attcgattct tactatgatg cttacaaagg tgttgtagct tatgttagag tatttgaagg
    54121 aactgttaaa aagggtatga caataaaaat gatgaatacc aataaaaagt ttgaggtaac
    54181 tgaagttggt gttatggctc caggtcaaac tgaacttagt gaattatcag caggtgatgt
    54241 tggttatatt gctgctagta taaaagatat aagaagttgt cgtgttggtg atacaataac
    54301 agattcaaat aatcctacag aagaaccttt accaggatac aaaaaagcta ctccaatggt
    54361 atattgtggt atatatccag gagaaggaga aaagtatgag aatgttagag atgctcttga
    54421 aaagcttcaa gtaaatgatg ctgcacttga atatgaagct gagacttcag cagcactagg
    54481 atttggtttt agatgtggtt tcttaggtct tttacatatg gagataatgc aagaaagact
    54541 tgagagagaa tttaaccttg atataattac tacagctcca tctgttatat atagagttac
    54601 aaaaatggat ggagaggttg taatgataca aaatcctgca aacttaccag aaccatctga
    54661 gataaagatg atagaagagc ctatagtaaa aggagatata atagttccta aagactatgt
    54721 gggtgttgtt atggagcttt gccaggaaag acgtggaaat atgttaaata tggaatatat
    54781 agatgataga agagtaatgc ttcactatga ccttcctctc aatgaagttg tttacgattt
    54841 ctttgatgct ttaaaatcaa gaactagagg ttatggttct cttgattatg aggttaaagg
    54901 ttatgtagca tctacacttg taaaacttga tatattaatc aataaagagc aagtggatgc
    54961 acttagtttt attgtccatg agacacgtgc tttccctaga ggaaaggcaa tgtgtgagaa
    55021 attaaaagga gaaattccaa gacatcagtt tgctatacca atacaagctg ctgttggtaa
    55081 taaggttatt gcaagagaaa caataagcgc tctaagaaaa gatgttcttg ctaaatgtta
    55141 tggtggagat atatctcgta agaagaaact tcttgaaaaa caaaaagaag gtaagaagcg
    55201 tatgagacaa attggttctg ttgaagttcc tcaaaaagca tttatgtctg tgcttaaatt
    55261 agatgagtaa atccttataa atttagataa agatatttaa aagctagagt gattttagaa
    55321 ttatttctaa attagtctag cttttttatg gtatatttta agtaaactca tagagaatat
    55381 aagtaagaat attaaagaag aataaaaagg tgatatttat gattaatata gaaattccta
    55441 aaaaagtaga ctatataatt aaagaattag aaaagaatgg ttatgaagct tatatagttg
    55501 gaggatgtgt tagagattgt ttattagaaa gagttccaaa cgattgggat ataacaacta
    55561 gtgctagacc agaagtggta gtagaattat ttgaaaaaac aattccaact ggtatacaac
    55621 atgggactgt aacagttatg attgaacatg aaccatttga agtgacgact tatagaattg
    55681 atggaaatta tagtgatggt agacatccag attcaataga atttacaaat aacatagtta
    55741 aggacttgtc aagaagagat tttactatca attcaattgc atacaattca aagacaggat
    55801 tagtcgaccc atttaatggc tatgaagata tacaaaataa gtatatacgt tgtgttggaa
    55861 atccagtaga tagatttgaa gaagatgcac ttagaatgct tagagcagtt agattttcag
    55921 cacaactcaa ttttaaaata gctgaaggta ctaagcaaag tattcataaa aaagcagatt
    55981 tgataaaaaa tgtttctatt gaaagaatcc agacagagtt taataaaata ttagtatctg
    56041 attcatctaa attaaactta ttaaaatcaa caggtttgtt gaaatttata attcctgaaa
    56101 tatgtgaatt agaagatgtt actcaacaca atccatatca catctatgat gtacaaaaac
    56161 atactttaat agctacagaa gtaattgaag atgaactgta tttaaaactt acaatgttgt
    56221 ttcatgattt aggtaaaaaa gtaactaaaa caactgataa aaatggtgtt gaccattttt
    56281 atactcatag tagagaatct gtaaagattg caaagaagat tttgaaaaga cttaagtatg
    56341 ataattatac tattaataaa gttttaatat taatacaata tcatgattat agaatagaac
    56401 ctaaaaggaa gataattaaa aagttattaa ataaacttga agatgttgaa ttatttgaag
    56461 atttaataaa agttaattgg gctgatacac ttgcaaaaaa tccaaagtat gcaaaacaaa
    56521 agatattaaa tcttattgag tgtgaaaaag aatttaaaca tataataaat caaaaggagt
    56581 gctttaatct taaagattta gctattaatg gaaaagattt gatatctata ggtataaaac
    56641 caggtaaaga tataggatat attttaaata agatgcttga aatagtcata aataatccag
    56701 agttaaatga aaaagaaata ctaaaagaaa aagcattaaa tatatataca
//
LOCUS       DAMJWC010000019        56141 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMJWC010000019 DAMJWC010000000
VERSION     DAMJWC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.019"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            33..1013
                     /locus_tag="PC503_001350"
     CDS             33..1013
                     /locus_tag="PC503_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2527355.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1112..2074)
                     /locus_tag="PC503_001351"
     CDS             complement(1112..2074)
                     /locus_tag="PC503_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2527356.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFAWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(2390..3340)
                     /gene="hpdA"
                     /locus_tag="PC503_001352"
     CDS             complement(2390..3340)
                     /gene="hpdA"
                     /locus_tag="PC503_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF2527357.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(3333..3590)
                     /gene="hpdC"
                     /locus_tag="PC503_001353"
     CDS             complement(3333..3590)
                     /gene="hpdC"
                     /locus_tag="PC503_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF2527358.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(3594..6302)
                     /gene="hpdB"
                     /locus_tag="PC503_001354"
     CDS             complement(3594..6302)
                     /gene="hpdB"
                     /locus_tag="PC503_001354"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF2527359.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(6599..7615)
                     /gene="tsaD"
                     /locus_tag="PC503_001355"
     CDS             complement(6599..7615)
                     /gene="tsaD"
                     /locus_tag="PC503_001355"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF2527360.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(7621..8097)
                     /gene="rimI"
                     /locus_tag="PC503_001356"
     CDS             complement(7621..8097)
                     /gene="rimI"
                     /locus_tag="PC503_001356"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF2527361.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8087..8803)
                     /gene="tsaB"
                     /locus_tag="PC503_001357"
     CDS             complement(8087..8803)
                     /gene="tsaB"
                     /locus_tag="PC503_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF2527362.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(8803..9255)
                     /gene="tsaE"
                     /locus_tag="PC503_001358"
     CDS             complement(8803..9255)
                     /gene="tsaE"
                     /locus_tag="PC503_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF2527363.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(9394..10434)
                     /locus_tag="PC503_001359"
     CDS             complement(9394..10434)
                     /locus_tag="PC503_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2527364.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(10763..11368)
                     /locus_tag="PC503_001360"
     CDS             complement(10763..11368)
                     /locus_tag="PC503_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2527365.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(11493..11610)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(11670..12836)
                     /locus_tag="PC503_001361"
     CDS             complement(11670..12836)
                     /locus_tag="PC503_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2527366.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(12984..15125)
                     /locus_tag="PC503_001362"
     CDS             complement(12984..15125)
                     /locus_tag="PC503_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF2527367.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15269..16376)
                     /gene="prfB"
                     /locus_tag="PC503_001363"
     CDS             complement(join(15269..16300,16302..16376))
                     /gene="prfB"
                     /locus_tag="PC503_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF2527368.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(16391..19066)
                     /gene="secA"
                     /locus_tag="PC503_001364"
     CDS             complement(16391..19066)
                     /gene="secA"
                     /locus_tag="PC503_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2527369.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19198..19749)
                     /gene="raiA"
                     /locus_tag="PC503_001365"
     CDS             complement(19198..19749)
                     /gene="raiA"
                     /locus_tag="PC503_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2527370.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQENYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20302..20976)
                     /locus_tag="PC503_001366"
     CDS             complement(20302..20976)
                     /locus_tag="PC503_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF2527371.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(20979..22031)
                     /locus_tag="PC503_001367"
     CDS             complement(20979..22031)
                     /locus_tag="PC503_001367"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF2527372.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(22080..23039)
                     /locus_tag="PC503_001368"
     CDS             complement(22080..23039)
                     /locus_tag="PC503_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF2527373.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23132..23653)
                     /locus_tag="PC503_001369"
     CDS             complement(23132..23653)
                     /locus_tag="PC503_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF2527374.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            complement(23664..24998)
                     /gene="celB"
                     /locus_tag="PC503_001370"
     CDS             complement(23664..24998)
                     /gene="celB"
                     /locus_tag="PC503_001370"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF2527375.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(25037..25363)
                     /locus_tag="PC503_001371"
     CDS             complement(25037..25363)
                     /locus_tag="PC503_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527376.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(25387..25695)
                     /locus_tag="PC503_001372"
     CDS             complement(25387..25695)
                     /locus_tag="PC503_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2527377.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(25836..27749)
                     /locus_tag="PC503_001373"
     CDS             complement(25836..27749)
                     /locus_tag="PC503_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2527378.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(28081..28863)
                     /locus_tag="PC503_001374"
     CDS             complement(28081..28863)
                     /locus_tag="PC503_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF2527379.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(28866..31085)
                     /locus_tag="PC503_001375"
     CDS             complement(28866..31085)
                     /locus_tag="PC503_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF2527380.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEENFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(31349..32446)
                     /locus_tag="PC503_001376"
     CDS             complement(31349..32446)
                     /locus_tag="PC503_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527381.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(32761..33954)
                     /locus_tag="PC503_001377"
     CDS             complement(32761..33954)
                     /locus_tag="PC503_001377"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF2527382.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34091..34194)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            34383..34892
                     /gene="yyaC"
                     /locus_tag="PC503_001378"
     CDS             34383..34892
                     /gene="yyaC"
                     /locus_tag="PC503_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF2527383.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(35003..35431)
                     /gene="fabZ"
                     /locus_tag="PC503_001379"
     CDS             complement(35003..35431)
                     /gene="fabZ"
                     /locus_tag="PC503_001379"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF2527384.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNITVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(35447..36466)
                     /locus_tag="PC503_001380"
     CDS             complement(35447..36466)
                     /locus_tag="PC503_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2527385.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(36663..36923)
                     /gene="spoIIID"
                     /locus_tag="PC503_001381"
     CDS             complement(36663..36923)
                     /gene="spoIIID"
                     /locus_tag="PC503_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF2527386.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(37021..37689)
                     /locus_tag="PC503_001382"
     CDS             complement(37021..37689)
                     /locus_tag="PC503_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF2527387.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(37755..38819)
                     /gene="spoIID"
                     /locus_tag="PC503_001383"
     CDS             complement(37755..38819)
                     /gene="spoIID"
                     /locus_tag="PC503_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF2527388.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(38906..40159)
                     /gene="murA"
                     /locus_tag="PC503_001384"
     CDS             complement(38906..40159)
                     /gene="murA"
                     /locus_tag="PC503_001384"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF2527389.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40180..40917)
                     /locus_tag="PC503_001385"
     CDS             complement(40180..40917)
                     /locus_tag="PC503_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF2527390.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            complement(41366..42661)
                     /locus_tag="PC503_001386"
     CDS             complement(41366..42661)
                     /locus_tag="PC503_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF2527391.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWREESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            complement(43112..44944)
                     /gene="glmS"
                     /locus_tag="PC503_001387"
     CDS             complement(43112..44944)
                     /gene="glmS"
                     /locus_tag="PC503_001387"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF2527392.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            complement(45211..46557)
                     /locus_tag="PC503_001388"
     CDS             complement(45211..46557)
                     /locus_tag="PC503_001388"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF2527393.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            complement(46727..47284)
                     /locus_tag="PC503_001389"
     CDS             complement(46727..47284)
                     /locus_tag="PC503_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2527394.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            complement(47285..48037)
                     /locus_tag="PC503_001390"
     CDS             complement(47285..48037)
                     /locus_tag="PC503_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2527395.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            complement(48037..49116)
                     /locus_tag="PC503_001391"
     CDS             complement(48037..49116)
                     /locus_tag="PC503_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2527396.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            complement(49145..49360)
                     /locus_tag="PC503_001392"
     CDS             complement(49145..49360)
                     /locus_tag="PC503_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2527397.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            complement(49403..50080)
                     /locus_tag="PC503_001393"
     CDS             complement(49403..50080)
                     /locus_tag="PC503_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2527398.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            complement(50070..51149)
                     /gene="buk"
                     /locus_tag="PC503_001394"
     CDS             complement(50070..51149)
                     /gene="buk"
                     /locus_tag="PC503_001394"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2527399.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLA
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            complement(51171..52073)
                     /gene="ptb"
                     /locus_tag="PC503_001395"
     CDS             complement(51171..52073)
                     /gene="ptb"
                     /locus_tag="PC503_001395"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF2527400.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            complement(52377..53558)
                     /locus_tag="PC503_001396"
     CDS             complement(52377..53558)
                     /locus_tag="PC503_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527401.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESMEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            complement(53555..54394)
                     /locus_tag="PC503_001397"
     CDS             complement(53555..54394)
                     /locus_tag="PC503_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF2527402.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            complement(55378..55451)
                     /locus_tag="PC503_001398"
     tRNA            complement(55378..55451)
                     /locus_tag="PC503_001398"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55415..55417),aa:Arg,seq:tct)
     gene            complement(55461..55535)
                     /locus_tag="PC503_001399"
     tRNA            complement(55461..55535)
                     /locus_tag="PC503_001399"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55501..55503),aa:Gly,seq:gcc)
     gene            complement(55546..55622)
                     /locus_tag="PC503_001400"
     tRNA            complement(55546..55622)
                     /locus_tag="PC503_001400"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55586..55588),aa:Asp,seq:gtc)
     gene            complement(55628..55703)
                     /locus_tag="PC503_001401"
     tRNA            complement(55628..55703)
                     /locus_tag="PC503_001401"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55668..55670),aa:Val,seq:tac)
     gene            complement(55709..55782)
                     /locus_tag="PC503_001402"
     tRNA            complement(55709..55782)
                     /locus_tag="PC503_001402"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55748..55750),aa:Gly,seq:tcc)
     gene            complement(55797..55871)
                     /locus_tag="PC503_001403"
     tRNA            complement(55797..55871)
                     /locus_tag="PC503_001403"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55836..55838),aa:Glu,seq:ttc)
     gene            complement(55879..55954)
                     /locus_tag="PC503_001404"
     tRNA            complement(55879..55954)
                     /locus_tag="PC503_001404"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55919..55921),aa:Met,seq:cat)
     gene            complement(55970..56055)
                     /locus_tag="PC503_001405"
     tRNA            complement(55970..56055)
                     /locus_tag="PC503_001405"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56019..56021),aa:Leu,seq:taa)
     gene            complement(56061..56135)
                     /locus_tag="PC503_001406"
     tRNA            complement(56061..56135)
                     /locus_tag="PC503_001406"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56101..56103),aa:Asn,seq:gtt)
BASE COUNT        16948 a        10627 c         6054 g        22512 t
ORIGIN      
        1 aagaatctat attgtaaagg agtattaaat taatgaactt aaaattaata tggataaata
       61 ttctaaaccc agtatttatt aaaaatgaaa taaaaagaaa aaaaatacaa attattatct
      121 ttttctttat aaactttggt ttaacttatt cattaggttt actgttatat tataataaat
      181 ttattgatcc agaaaacttt gcatcattca tgatgatatt acctctatct tcagttgcca
      241 ttgcaaagtt ttatactgaa ggattaaata atgatatgta tgaattttat tcactaatca
      301 tattattttt tcttatttat tcattattaa ttgttcttaa gttattaaat ctaataaata
      361 ataatgaatt tataattata aacctaatat taacttttat aagtagctta tcaattataa
      421 tatattcatc aaataaaaaa aatttatatc ctgtaaaaaa tattaaacta ggttctttat
      481 taattattta ctttatgatt tctgtaattg ttccaacatc atttatacta atactacaag
      541 gggctcaacc taattatagt ggtatcataa aatttatatt tactccaata acatcattaa
      601 ctactattta tatttttttt agtgaagaat atgcctggag aggtttttta cagaatattt
      661 tttttgataa atttggtaaa aagttaggag ttataatatt aggtatgtgt tggagcttgt
      721 ggcacttacc actaatattt acattatata cacctgaagc gccaatatta ggaataatat
      781 tacgttcaat acatatagtt ggaatttcaa tatttttagg atatctttat ataaaaacta
      841 agaatatctg gttttgtgct ataattcatg ttttaaataa tagtgctttt cttatcacaa
      901 attctaaaga atcaactatc acttaccatg atatactaat agtatctatg gttgttttaa
      961 ttttttatgt tccatttcta tttacaaaag aatataaaaa taacttggag taaatagaat
     1021 atccaagtta tttttatatt tttgcaaatt tccaacaatc ctacagaata ctttaagctt
     1081 agaagatatt attaaaattt attataatca actaattctt gatattggtc acatttactt
     1141 tatcactaac aaaatcatac ttagaatctc tatagtaata ccatacaaat ataaagctaa
     1201 gtagattaac aaaagtagtc aaaattccac cttcaatacc aaacattcct ccatttaata
     1261 gattaccatg agtgatttgt gtagttataa tccctggaac ttgaagtcca cttacaggca
     1321 taccatatat aatcccctga aatacattcc atgcaaaatg ataacctata cacatccata
     1381 tattcgacga ttttataaac atatatgaaa aaagaatccc aataattata atattaatta
     1441 cagacaaaaa agtaacatca ggattccata tatgaatcaa cccaaaaata acagatggaa
     1501 caatcattat aaaataaata tttttacatc ttcgtaaaac tgccataaaa aaaccacgat
     1561 ttaaaatttc ttctgcaaaa gcaactaaaa taaagaccag tatccaagaa actgttaaag
     1621 gtgaaatttt tggtacccat gaagtaacat gaccaccacc aattgttatt gttataataa
     1681 agattactgt acaattaaat attcctaata acattcctac atatccttct tttttcttaa
     1741 ttctataaga atgtaatccc atttcactaa taggattttt cataataaat ctccatacaa
     1801 ttataggaat aataatcata agtgaatctg ttagaatttg aaatacaatc tgtaacccaa
     1861 catcatttaa ccaattagca tattctgaaa aatagtttgt ttttaaatta atgtcacctg
     1921 tagcaaccag gatttttctt attatttcca caagtatcat gcttaaataa tactgaagta
     1981 tgtaaaaggt agccataaca gctataataa tccaccctga acgtactttt ttgtctttat
     2041 tcttaataat caagttgctc catgatttgt tcatatagat gtcttcctcc taactattat
     2101 ttttagttgt ttctaaaata tattctatta aattttttca tagtagtatt ttaccacaaa
     2161 acttctgctt caatgaagta agcgtaatat attctctaac tgtaatttaa actataaaaa
     2221 atatataaag tatatttaaa gcaatattta tggacataaa gcaatataaa caatatataa
     2281 aacatataaa actttactta attatttcta cataaaaacc acataaaaaa ggatgtaact
     2341 ctagctttta gtgtaacatc ctttttttaa ttaaaacttg tatttaattt tagaaagctg
     2401 tctcatgacc aacataacaa gctataccat tatccaaaaa tatatcttgt aattcttcaa
     2461 gatgaccttc atcaacatca cccttatcag aatactcata ttccttgcct aattgaatcc
     2521 attttgattc tcctaatctg tgaaatggta atagattaat ttctaccaaa ttatttttgt
     2581 gcataaaaga tataatatca cttatatttt caacactatc attaaaccca gagataactg
     2641 gtactctaag tactaatctt ccattccaat cagaatttgc aaggtttgat atattttcta
     2701 atattaaatc attatacaca cctgtttgtt ctttgtgttt ttctctatcc atatgcttta
     2761 tatcaataaa tgcaaaatca atatcgttaa atattttatt aaaaacttca tttgatacac
     2821 atgcactcgt ttcaatggca gtgtgtatat ttacctcatg acactttaat aatacttcat
     2881 gtaaaaattc atgctgaagt agtggctcac ctccactaaa tgttactcct ccattacttc
     2941 tccaattgtt agaatcacgt ttaattacct gcacaagttc atctacagtg taaggttttg
     3001 cacataattt aaacgcatta taataacatg agttgacgca ttcaaaactt tcacagtcct
     3061 tacagatgtt ccaatctata actggcttat tatcaagatt aaagctcaat gcaccatttt
     3121 tacacttacc atgacataca gtacatccat tttcatattg acaagataat tcactaaaca
     3181 tcatatgtgg tcttacagtc caactttctg gatttgcaca ccatttacaa ctcagtggac
     3241 atccatttaa aaatacagtt gttctacaac ctggaccatc atgaactgaa aagctttgta
     3301 catcaaaaat catgccttct aattgctttt gactactcat taaacacatg tccttcacaa
     3361 gtaattgcat tcaatgttga atatacccag tcttctttct ctaggccaac acatttgcct
     3421 ataccttcat cattagcttc aacaaaattt ttacaatttt tacattttgg cattactttt
     3481 atctctggac atgctgcatc atctaaatta atcatttgtt ttgataatct acaaattcct
     3541 ttggttgcat ctactgcaca aaaattcata caatcactat gctttctcat attttacacc
     3601 ccttcatact ctgttctagc aattacttca tcttgtattg gtttacctaa ttcacaccaa
     3661 tattgagtaa acccagcaac acgtaccatt aattgacgat aattgtcagg atttttttgt
     3721 gcatctttta atgtttctga atctacaaca ttatattgaa tatggaaccc accttttctt
     3781 aaataacttc ttgttaaatc taataatttt ttagttcctt gttgtccttt tatagtagtt
     3841 ggatgaagtt ttaaattcat ctgagaattt tgaactactg cttggtccca aatagttgca
     3901 gattcaaata atgcatatac tccattttta tctgttcctg catatgcaga gactgaacca
     3961 tctgaatatg ttgttccact tagtctacca tctggagtag ccaaggtagc agctccctgt
     4021 ggcccatgtg tagaaacaga tatttggcaa gggtacatct tcttagcata taaagattgt
     4081 gcttcttcac atacttttga taaccatacc tcatagtttt taagaatatt atctgcatac
     4141 aaatcattat ttccatattt aggtgcatca agacaggcct tataaatagc atcatattta
     4201 ccagtcttat ctacttttac ttggtctgcc atagaataat ttcctacttc taatgcatct
     4261 ttaaatccaa aattatttaa tatggcatcc ttcatttcct ctattgtaaa tgctttgtca
     4321 tcatatacaa gtttcttaag tgctgcaaat gaattgacca tagtaacagt accacaagtt
     4381 tctacgttta atgttgcatt ataacgatat cccatatttc ctatatgttg acctttgtct
     4441 aaacagtctg gctttagtag tgaatttatt atagaagtat caaattttct ccatatatct
     4501 aactcaatgt tatttgctct ttctaaaaca tttattgctt gtttataata atctttaaat
     4561 acttctatga cttcttcata agtatctaat ggcttattat gaggctcaaa tacttgtata
     4621 ttcatacgat agtctttacc attcataaga acaagttcta aaatttttgg attagctata
     4681 aagtgaactc cagagccagc agattgacct gctccacctg caatagagta tgtttttccg
     4741 tttaaagtta actgtttcca acaccctgga gacgtttcca aacatccacc taatgcaaat
     4801 gctcttgctt cttcaacagt cataccttca tcagcaaatt gtttcatcat aaatgttgtt
     4861 ccatttgagt tgtttaccca tgctggataa ccagaaccaa gctttgtaca ttcagcagct
     4921 ttcattaaga aatcttctgg aagcttttca tcatatagca tagttaaact aggttgagga
     4981 gttctacatc tcatacttgc ttctaataat aactcttcta gttcattagc tcctgtagaa
     5041 ccatcttctt ttaatccacc tatagataaa gtattaaatg tattgcctga tagtactcct
     5101 ccatttacgc ccgctgaagc aaaacagtca atacaagtga tttttattct ataaagctct
     5161 aataattcga taacctcttc ttttgtaatt agtccttttt ctatatcttg ttcataccaa
     5221 ggatataaaa tttgaccaaa acgtcctata gacataccag atatagcatc ctcatttact
     5281 gatgctatat gaattgtata agtcaactga agagcttccc taaatgtacg aggttgttta
     5341 tgtgcaatat gttctaatat ctccactaaa tctgagtatt cttttttagc ttctaaatct
     5401 gtctctatac tttctaaata ttttgcatgt tttgcataat ttaaaatcca agtttgtaat
     5461 ccttcaataa cttgaataac agcctcataa aaatatagac ggtccatacc aataagccca
     5521 tctccagatg catttcctgc aactgccttt ttacattctt ttgccatttc tataattcca
     5581 tctaatccat aatttaaagg ataaaaataa tttataactt ctctaccttg aggaagtgta
     5641 taccctgaat caaacatgca tataagtgta ctcattaggt tttcttttaa atcataatct
     5701 ggcatcattt tttcatagtg aaaacctaaa tcttcaacag actttccaac ccattccttt
     5761 gccattttta caagtacagg tacttcttct tttctcattc cgaatttacc agctattgaa
     5821 acgacatttc caaaactttc agtaacattt cctccaccag acccaaattt tgtaagttca
     5881 tcagctgtgt tactggctaa tttctttgcc tcttctctca tttgttctcc ttgagcaaca
     5941 aagaagcttt cacttaccca tggcattgga aaagaacctc tataatggcg tgtcttttgc
     6001 attactattt tctcaccagg tattatattt ggtgtcatat gtgaaaaagc agctttaaga
     6061 gctttagctc ttctaactac tggtatatca ccatctgatt ttctatattc tctattatac
     6121 caatatggaa attccatatc agcagtagat aatgtattat aatatacatc taataagtct
     6181 tctgctcttt tacttgcttt tttttcatta aattcactta aattttcttt attttgaaaa
     6241 tttgatttaa tattttttgc ttccaaaata cttcttattt tgtcttcttt actttgactc
     6301 atttcttccc ctccttaatc tttctataat tagtataaaa ctttttaaga atgaaaaaaa
     6361 agggtatatt acccactttt taaaataatc tttctataga aaaaaataaa cttgaagcaa
     6421 atctaagcca aagacaatct gtatatccta aaatttgttg caattcattg gaatataaag
     6481 attataaata gttttacttc aagttttaat atatactata tttattttta ttatatttaa
     6541 tttcacttct acttactttt ttgaaacaat acttttatat ttacaaattc atctaactct
     6601 actgatttat ctttaaattt ggaactgcat ttaaactcat atcatgcgtt ttcccattta
     6661 taaaattata atatcctgca caccctatca tagctgcatt atctgtgcat aaaattagag
     6721 gaggatactt aacagtaata ccattgtctt tagcaagctc tgttatttta gctctaagcc
     6781 ccgaattaga agcaacccca ccagaaagag ttatgatatt gtatcctttg tcttttactg
     6841 cttttagtgc tttagtagat aaaacctcta ctacagcctc ttggaaagat gctgctacat
     6901 cttcaactac tatttcttca tttttcattc tttttccatt tagataattt aatacagaag
     6961 attttaatcc actaaaacta aaatcatagc tatcttcttc taaataggct cttggaaatt
     7021 ctatagcatg tttatttcca ttcttggcca gattatcaat aataggacct cctggatagc
     7081 ctaaattcat agctcttgaa atcttatcaa atgcttctcc agatgcatca tctcttgttt
     7141 ttcctaaaat ttcatacttg ccataatctt ttacttcaac caagtgagta tgacctccag
     7201 atactattaa tgttataaaa ggaggtttta aatccttatg ctctatatag tttgcactta
     7261 gatgcccttc tatatgattt actcctacaa gtggaatatt caaagtatat gcaagtgctt
     7321 tagcataaga tagaccaacc aataaagcac ctactagccc aggtccatat gtaactgcga
     7381 tatggtctat atcattaaaa cctatatttg ctttgtctaa agcttcttga acaactatat
     7441 caatattttc cacatgtttt cttgaggcca cttctggaac tacaccacca aattttttat
     7501 gtgtctcgat ttgagtagag attatgtttg aaagtacttc tctaccattt tttaaaactg
     7561 atgcagctgt ttcgtcacaa ctactctcta tagctaatgt tattatatca ctcataaact
     7621 ctacacctct tttaattggt tccacattat aattgcatct tctttattat cactgtagta
     7681 ttcttttctt attccaccca ttttaaatcc atattttcta tataaatttt gtgctatttt
     7741 atttgatgct ctaacttcta atgtcataga tgcaatatta ttatctttac ataaatcaac
     7801 tatgcctttt atcaacttgt cccctatttt tttccctcta tagtcactat gaacagccac
     7861 attatttata tgcccttcat caagtataag ccaaattccc acatatccga caatttttcc
     7921 atttaactta gctactatat accttgctac ttcattagac aactcttttc taaaagactc
     7981 ttttgaccaa taatcttcaa aacaattttt ttctacttca aaaacttcat ctatatcttc
     8041 tgtagtcatt tcttctattt ttatatcatc tactattagt tttgtattat cttccattat
     8101 ttagcctctt cattttttca tcatattgta cttcagcttg agattttctg atatacatag
     8161 gatttatcgt ataacaagta tgtacatcta tatttttatt atatttattt aatgctaaag
     8221 agcataagct tcctgcgtta gatacattat tagctggtga aggtattttt atatttttta
     8281 tattctctaa cttgtcttta tatttgtata cagcttctcc aactattata aattcttcat
     8341 tagttgatac aatttcatct actaaagcat caaactctac aacatcaaca ccatctaatt
     8401 ctatcatctc tccattttca aacttgtatt tagctgaata aacttgattt ttctgtgcat
     8461 ctaatataca acatatcttt ctatcacaga aatttatgtt atttgctaga gattccaaag
     8521 aatttactgc tattattggt atattattta catgggccat agcttttact gtagccatac
     8581 ctattctaag tcctgtaaac gaacctggac ctatacatac agctaataaa tccatatctt
     8641 ttatacttaa atcactcata ctcaacatat tttctatcat tggcataagc ttttgtgaat
     8701 gagttttttt gttgtttact gtaaactcac atattaagtt atcatcttca acaactgcta
     8761 cacttgctgc catagaagac gtatccatac ctagtatttt cattatttaa tcaactcctc
     8821 aactatctct ttataaaact ctccttttgg agttaatatc atttctcttc cttcatcttt
     8881 atatctcaat tctatattca aatattcttt tggaagtata tcttctatta gattagccca
     8941 ttctattata cagattccat ttgaatttac atattcatca taaccaatat catacatttc
     9001 atcactacta cctattctat aaacatcaaa atgatacaaa ggtatttttc cttcatattc
     9061 atttattata gtaaaagtag gacttgttat ataatcttct atccctaatg aatctgccaa
     9121 actttgtgtc attgtagttt taccagctcc taaatctcct actaaacaga taacactgcc
     9181 ttcttttaaa agtttaccta atttatatcc tatttctcta gttttatttt cattttctaa
     9241 atatattttt gccatcaatt catctccatt ttgatataat cgtcatgtga atttatatca
     9301 ctgcttaatt aattatagta taagcctaga ttattataaa gtacttgtct ttatcttttt
     9361 ttatctttca ctattgatgg ctgtatctac accttatata caatcatcaa tagcaatttt
     9421 tacatactct tttgctttat ggttttgctt caatgcttct ttacatattc tctcagattg
     9481 ctcttttaca tacttaagag acttatagtt ctcttttact gcttcaatac acattttttc
     9541 tgtttgattt tttatataca taagcatttt tccattttgt cttacaatct ctatacatat
     9601 atcttctgta tacttatcta tgtaacttag tacatcttta atattatatt ttttatttaa
     9661 atatcttata gcatttatac atatttcttc tgtcttattg ttgacaaatt gtatacttct
     9721 tccatcttgt ttgacagctt ctatacatat tttatcagtt tgtttattta catattgtaa
     9781 tgccatacca ttttgtctta cggattctat acacattttt tccgtttgat tttttacata
     9841 ttttaatgct ttataatttt gcttaatggc ctctatacat aattcttcac tctgttctct
     9901 aacgtatgca agacacctgc catctttttt aattgcttct aaacatatcc ttcttgtttg
     9961 agtctctaaa gcctttagta tacttacaac atctatattg gaagaatgac ttattgcttt
    10021 tataataagc ccttctgttt tatttcgtac atacttaagt gcattacaat ctttttttat
    10081 agcttcaaga cacaagtatt ctgtttgttc ttttacatat tcaagtgctt tataattata
    10141 ctttattgct tctaaacata attcttcggt ttgatttttt acatactcta atgccttgta
    10201 attctgcctt attgctaaaa tacacatacc atcagtttga ttttctatat tttttaattc
    10261 acgataatcg tattttaccc tttccatatt ttcaatatat tcattagtga tatactttaa
    10321 agaatctcct aattttgtat cataaatacc aatatgaata tctttccaat tactattaaa
    10381 ataataccct ttatcatcta aaaataattt ttttattttt ttagataaat gcatgaatat
    10441 acacccctat cattattaaa ttagttatta ttaaaagttt gattattaat ctttatagtt
    10501 ttttaataat aactttattt tttgtttatt ataaattcgc tctgtatatt gtagatacct
    10561 ttttcatatt ttaatagtta atcgttttaa ttcttccttt attttaaaat ttaaatttgt
    10621 ctaaatattt cttattttat atacattttt tgataaatta ataaagccat aatatattta
    10681 atatatcaat cacaatatag gactgaagtt ataaataaat tatggctatt caatacattt
    10741 aattttatat tttcttgtct aattatttct ttattatatt tcccattttt ttataaagtg
    10801 gcaatgttac taaagatatt ataacagcct tcagcacatt aaatggagct atcatccaaa
    10861 ttacaaaagt gaataaatca tgaacttgag gatttatagc tgaacctaaa cctattatag
    10921 catctagtcc cataagttga ccataaagtg gcaacattac aaaataattt actaatgaac
    10981 caattatagt catagatatt gttcctaata caaaaccaat cagtacacct tttaaatctc
    11041 cacttctctt atatgaataa caaagtatca ttacataaga accaccaatt aatatatttg
    11101 caaattctcc tattcctcca gttgttgttg ctgttattgc ttgtaacaca ttttttacta
    11161 caactattcc aaatccaact aatggtccta gagacattcc tccgaatatt gctggaatat
    11221 ctgataagtc aatttttaag aaatctggaa atatacctgg tattggtgct tgaataaaca
    11281 ttaataaata agatattgca gataaaattg acattactac taaagttctt gttgaaatca
    11341 tattgcctct ttttgctgtg ttttgcataa ttattttccc cctaatcaat atgtttatat
    11401 tttttaggaa aaacaaaaaa ctcgaagacc ctatcttcga gtttttatgg atatagttta
    11461 aacaaactaa aataaactta tttatcttcc ataaatatct tctctcatcc agactttact
    11521 gtcggctttg gaatctcacc aaatcaacca cctaagtagt tcgcgggcta taccgccggt
    11581 agggaatttc accctgcccc gaagatcttc tttgattttt taattttcct tacactctta
    11641 tattagttaa ttttttaata attgtcaagt tattttttct catacactac tttgccattt
    11701 attatagtgt aaagtacatt actttgaatc tctagtggag aattatccca aattactagg
    11761 tctgcatctt taccaacttc tatagagcct actctatctt ctattcctaa agccttagct
    11821 ggatttatcg taattgattc tattgctttt tcttctttca taccatgttt tactgcaata
    11881 cctgcacata ttggaagata ttgaactggt attactggat ggtctgtcat tatacataca
    11941 tcaagacctg catttgaaag tattcctgct gtattaaatg tcaaatttct aagctcaaat
    12001 ttagaccttt ctgacaaaga tggccctact attacaggaa acccttcttc cactaattca
    12061 tctacaataa gatgaccttc tgtacaatgg tctaatgtaa gctttaaatt aaattctttt
    12121 gcaattctta ttgctgtaaa catatcatct gctctatgag catgtgcctt aaaaggaatt
    12181 tctcttctta aaactggtat taaactttcc atttttatat catattcagg tttttcacag
    12241 tcttcatcat catgactctc atacatatca atatcctcta aatattcttc tgcttttttt
    12301 aggttttctc taagtaaagc agctatagcc attctagttt gaggagattt atcatcctga
    12361 ccataacagc tctttggatt ttctccaaaa gcaattttag atgcaactgg attttttatt
    12421 accattttat caattctttt tccacatgtc tttatagcta tacattgacc acccataaca
    12481 tttgcacttc caggggttgt acaaacagaa gttattccac cttcaaaagc ttctttaaaa
    12541 gttctatcca ttggattaat tccatctata ggatttaatt gtggtgttat tgggtcagtc
    12601 tcttcatttc catctgctcc ttcaaaccct ataccatctt cccataaacc taagtgagta
    12661 tgagcatcta taaatccagg aaacacaagt ttattactag catctattac ctctacatct
    12721 aaaggagcta tcaaatcttc tccaatttct attatttttc cttcatctat aagtatatct
    12781 ccatgaatta tcccatttgt tatggtattt attttaccat tttttataaa aatcattcat
    12841 tttcctcctg attttcaaga ctatcgttct tattttaata tattttctta ctatatactt
    12901 ttacaaattt ttaacattta tacactcgag taatcttatt tacaaatata gaatctaagt
    12961 actataacca tacataaact tatctatttt ttcattgata aggcaactct ttttttgttt
    13021 aagtcaattc caatgacttt tacatctact atatcaccta ctgtaacaat actcataggg
    13081 tctttcacaa aactattact catttctgat ttatgaacta atccgtcatt ttttattcca
    13141 atatctacaa atgcaccaaa gtctacaaca tttcttattg taccttttaa agtcataccc
    13201 tcttgtatat cttcaatttt taagacatca gttctaagta taggttttat accttcttct
    13261 cttgggtctc ttcctggttt tttgatttca gctatgatat cttttaacgt aacttgtcct
    13321 acttccagtt tttcacttaa ttccctcaag ccaatttctt ttattttttc atctatttca
    13381 cctatattct tattctttac atcatctaaa gaatatccaa ttatctcaat cattttttta
    13441 catatatcat aactttcagg atgcacacct gtattatcta gtggattttt accctctaag
    13501 attctcataa atccagcaca ttgagtaaat gcttgaggtc ctagtctttt tacttttttc
    13561 aattgtgctc ttgacgtaaa atctccattt tcttctctat atgctattat attttttgct
    13621 atagctttac ttattcctgc aacatgttct agtagggagt atgatgcagt atttaaatct
    13681 actccaacac tatttacaga atcttcaaca actccatcta gtacttcttc taatctcttt
    13741 ttgtttaaat catgctgata ttgaccaaca ccaatacttt tagggtctat ttttacaagc
    13801 tctgctaatg ggtcttgtaa tcttctagct atagatatag ctcctcttat tgatacattt
    13861 atatctggat gttcctcatt tgcaagttca gatgctgaat aaacagatgc tcctgcttca
    13921 ctaactatca catactgcac ttcgctatct atttctttta tcatttctga tacaaaagtt
    13981 tctgattctc tagatgcagt accatttcca attgaaatta tatctatatc gtatttttca
    14041 atcaatcctt ttaaaacttt ctttgctccc tctacatcat tttgagggtc tgttggatat
    14101 actgttgtat aatctagtag tttaccattt ttatctacta cagctatttt acatccagtt
    14161 ctaaatgcag ggtcaaatcc cataactact ttgtctttaa ctggtggttg aagcaataaa
    14221 cttttaacat tctttccaaa tacacttata gctctttctt gagctatttc tgttaaatga
    14281 tttcttattt ctctttctat tgatgggaaa attaatcttt tataagaatc ttctattgaa
    14341 cttacgattt cttctttatt tttgaaattt ttatcattta catattcgtt tattatgtaa
    14401 tttaaaactt tatcattatt tatttccaac ttaaccttta ggaagctttc tttttctcct
    14461 ctgtttattg ccaaaactct atgtggagcc atacttttta ctgcttcgct ataatcataa
    14521 tacatatcat aaaccgattt ctcatcagta gcacttttgc taactatcat accttctctt
    14581 aaagctaatt ctcttatata ctttctaatc ttagcatcat ctgagactag ttctgcaatt
    14641 atatctctag caccttttag agcatcttca atagaaagaa cttctttctc ttcatcaaga
    14701 taattctttg cctctatttc tatattatct aaattattct ctagtattga caatgctaaa
    14761 ttttctaatc ctttttcttt tgctattgtt gctctagttc ttttcttttg tttatatgga
    14821 gcatatatat cttctacttc ttgtaatgtt tttgcttttt ctatattttg tgttatttca
    14881 tctgttaatt tcccttgttc atctattagt ctaactacat catcttttct actttgaaga
    14941 tttctcaaat acattaattt ttcataaaat tctcttagtg taacatcact catttcgcca
    15001 gtcatttctt ttctatatct agctataaat ggtattgtat ttccttcatc aataagtttt
    15061 aatgtattat ttatttgttc atctctaaga ttaaactctt tttttaagat ttgatttata
    15121 tccaatttat tcactcctaa tgttagtttt tcataagtat aacaaaacag aacgaaggct
    15181 gagggttatc gtcctcagcc taagtgctgt aagtgcatat taagcactaa ccttcttata
    15241 catatatctt aattacagtg catatttatt aaactatttt attcattttt aagtattcat
    15301 taataaacaa gtctatattt ccattcatta cactatctac atttccaaac tcagcatttg
    15361 ttctatggtc tttaaccaat ttatatggtt gaaaaacata tgacctaatt tgactacccc
    15421 aagttatttg tgagtatttg ccttgtatat cttctatttt ttccttttgc tctaactctt
    15481 ttaattctat caatttcgcc attaaaagtc tcatagctct gtccttattt agatgctgag
    15541 acctttcatt ttggcactga actactacac cagtagggat atgtgttatt ctaactgctg
    15601 aatcagtcgt atttacatgt tgccctccag ctccagaagc tctatatgtg tctatcttta
    15661 aatctgatgg attaatttct acttctatat tttcatctaa ctctggtgtt acatctatag
    15721 atgcaaatga agtatgtctt tttcctgatg ggtcaaatgg agatattctc actaatctat
    15781 gaactccttt ttcactcttt aaatacccat aagcatttgt tccttctaca agaattgtag
    15841 ctgtctttat ccctgcttca gggtctgata ttatatctaa aagcttaact ttataaccct
    15901 tactttctga ccatcttata tacattctca aaagcatttg agcccaatct tgagcatcta
    15961 agccaccagt accagcattt atagataata tagcattatt tttatcatac tctccattta
    16021 gaagagtctt tattttcatt tcagataatt tttcttccat tgattctatg gacttttcta
    16081 tatctctttc tacagaatca tcatcttctt ctaaacctat ttcaattaat acttctatat
    16141 cttctaataa gctttttaag ctttcatatt cttctaatgt ctcttttaaa gatttatttt
    16201 cttgaagtac tctttgagcg acttcattat cattccaaaa atcttgttga ttcatctttt
    16261 cttcattaat ttgtatattt ttcatcaatg aagctatgtc aaagagaaac cctcaattct
    16321 tctaaatttg aagccatctg ctccatacta tgtctatact cttgtaactt taacatttaa
    16381 tcctccgaga ttatcttcca caacagtttt tatatttttt accacttcca caagggcata
    16441 agtcatttct tccaaccttt tcatcttttt taacagtttt acttgttgga agtgttccat
    16501 ctgatggaga agatagattt tcaacatcta caactgcttt tctttccact ggagtttcta
    16561 ttgttatatt aaataaatat cttacagtat cttctttgat atgtttattc atttcatcaa
    16621 acatatcaaa accttccatt ttataagcaa taactgggtc ttgctgacct acagcacgaa
    16681 gaccaatacc ttggcgtaat tggtccatag catctatatg gtctatccaa tggttatcaa
    16741 cagcttgaag taagattact ctctcaactt ctctcattct ctcatagcca acttgttctt
    16801 cttttgaagt atatatcttc atagctattt cataaacttt ttctgttatt tcaactggat
    16861 taagtttttc tatttctggt atttctatgc taccttttgg caagaacaga ttatacatat
    16921 gttctttgaa tccttcttca tcaaatcctt tatcttgtgt ataaagagta actgcttctt
    16981 ctattataga atgagtcatt gattgtattt gttcttgtaa atcttcacct tctaatacac
    17041 gttttctctc tgcatatatt atttctcttt gtttattcat aacatcatca tattgaagta
    17101 catgctttct tattccaaag tttttacctt cgactttctt ttgtgctcct tcaatagact
    17161 tagataatat tctatgttct atcggcatgt cttcttcaag acctatttta tctacaatac
    17221 cagatattct atcactacca aacaatctca taaggtcatc atcaagacct atatagaatc
    17281 ttgaactccc tgggtcacct tgacgtccag cacgacctct caactggtta tctattcttc
    17341 gagattcgtg tctttctgta cctataatag caagtccacc tgcttctaca acttgttttt
    17401 gttcttcttg tgtttgttgc ttaaactttt caaatagttt ttcatactct tctctagctt
    17461 caaatagaat ttcattacct tttacaggta taccttctat tggagtatct actctattta
    17521 ctatttcttc tttaaatcca tttcttctca tttctctctt agttaaaaag tctggatttc
    17581 cacctagaac tatatctgta ccacgaccag ccatattagt agctattgta acagctccaa
    17641 gtctaccagc ttgtgctatt atttctgcct ctttatcatg atgcttagca tttaatacct
    17701 cgtgctttat gccctttttc tttagtattt gtgataataa ttctgatttt tctattgata
    17761 ctgtacctac aagtattggt tgattgactt tgtgcctttc aattatttct tgtgctacag
    17821 cattaaattt acctatttca cttttgtata cacagtctgg taagtcttcc cttatcataa
    17881 gcttattagt aggtacttgg aaaacatcca ttttgtagat tgctttaaac tcttcttctt
    17941 ctgtttttgc tgtaccagtc atcccagaaa gttttttgta cattctaaag taattttgga
    18001 atgttacagt agctagtgtt ttagattctc tttgtatttt aagaccttct ttagcctcta
    18061 ttgcttgatg taaaccttct gaatatcttc taccaaacat aagtctacct gtgaactcat
    18121 ctactattac tatttctcca tctttagcaa cataatcaac atctttcttc attattacat
    18181 gtgctcttaa agcttgattt atatgatggt ataattctgt atgagatata tctgttatat
    18241 tatcaacatt aaaatacact tctgcttttt gtatacccga tgctgttaga gatacagcct
    18301 tatctttttc ttctaattca taatcatctg gttttaaggt taaaacaaat gtgtttgcat
    18361 ctgaatataa gtgagttgat ttgtctccag gtccagatat gataagtggt gttctagcct
    18421 catctattag tatagagtca acctcatcca ctatagcata atttaatcct ctttgaactc
    18481 tttgctcttt gtgtattacc atattgtcct ttagatagtc aaatccatat tcattatttg
    18541 taccataagt tatatcacaa tcatattgtt cttttctaac ttttggattt tgaccgtgta
    18601 taataacgcc tacactcatt cctaaaaact catagatttt tgccatttgg tctctatcac
    18661 gttttgcaag gtaatcattt actgttacaa catgtacacc ttttccagta agcgcattca
    18721 aataaacagg agcagttgca accaaagttt taccttcacc tgttttcatt tctgctattc
    18781 ttccttgatg tagtactata cctccaatca tttgaactct gtagtgtcta agtcctaaca
    18841 ctctcttaga aacttctcta actactgcaa aagcttctgg aagtatatca tctatacttt
    18901 caccatttgc taatctttct ttaaatatat ttgtcatatt tttaagttcc gagtctgcca
    18961 tagattcaaa tttaggttct aatgaatcta ttatatcaac agttttattg aactttttta
    19021 attctttttt atctgccatg ttgaataaat tatccataaa gctcatattt tacatctctc
    19081 ctcgttcttt attgtactat tattcatttt accataaaaa ctatactttt aatattaatt
    19141 taaaaagcta tcgataattt atttatcgat agctaatatg attaaatcta aattgcttta
    19201 ttcatgttct attataccat atccaccatt attacgctta taaactactg ctatttcatc
    19261 tgaatctatg ttcttgaaca tataaaaatc atgtcctatt aattccatct gtaatacagc
    19321 ttcttcttca ctcattggct taacactaaa tttcttacgt ctttgaatta ctaattcttg
    19381 attttcatcc ccataattct cttgttcatc agctagattt atctctgcat cttggaatct
    19441 tatactcttg ttgtctttat gtttatcttg taatctcttt ttatattttt ttaattgttt
    19501 acttaattta tcatatacaa catctatagc tgtgtataaa ttttcctgca tatcttctgc
    19561 tctaattata ggaccattta cagtagctat tgttacttct attttttgtc ttgcttttct
    19621 cgcacttact gtaactttta catcagtgtc tggatgaatg taattatcta acttacttag
    19681 tttagtttcg attttatttt ttattgcatc agttaattcg atttgttttc cagatataat
    19741 tatgttcata aatacatctc ccttcaatta tgccagtata agaaaattta tactttaata
    19801 atatattcta cacgaactct cataatcctc tttttattat ttacttttat gattttttct
    19861 attcaattga tagaattatt tatcattttt agttacattg atacttatgt ggattaatat
    19921 tattacaaac acctgtggat aatgtggata aaactgttaa taactcttgt ttttgtttat
    19981 ttaaagctat ttttactcct atttctatcc acaaaaatct ccattaattg tttattaata
    20041 tgtgaattca tgtcataaga tggtaatttt aggaaattat gtgtattata tgccaatata
    20101 cctttataat tttttaataa atataaaccc tctaaaacct ccataatcta tcttttcttt
    20161 cattatttat atttaaaact aattaaaagt tataaagcat actcaacaat aatttcatat
    20221 ttaataccta ttaacattca tatacccaaa ttataattaa cttactctct ttatttaaac
    20281 taagtatttt atattcatat actatcttga aattatattt acgagttgtt taagcttttg
    20341 tctatctata tcttcaaaag gactgttatt tattctaatc gctgtaccaa aatgaaaatt
    20401 acttgcctta gttaattcct ttatcttttc tatattatta aaattaagac ctccacctaa
    20461 aagaattttt atgtgattag aactaagcat catattcttt atcatttgta tgttatcaac
    20521 tatacttcct ttccctcctg atgttaatat attcgtaatt ttatcataat ccttcaaaat
    20581 tttaacacta tctattgtat ttgattcatc tattgctcta tgaaatgtaa catcaagatt
    20641 atcacaacat ttcaataaaa catttagatt tttctcatct atactattgt ttttatccaa
    20701 tacaccaaat acaactccat tagcaccaat ctctttaacc acacttatat ctttttgcat
    20761 tatacttata tcttctttac tgtatacaaa acttttcgca tgatgtctta tcattacgtt
    20821 cacaggtatc tttacactgt taacaacact ttctataaga ccaaaacttg gtgtcaatcc
    20881 accttcagtt aaagcactaa ctaactctat tctatctgca ccacaatctt ctataatttt
    20941 agcgtcttct actgacattc ctattatttc taacataact actcctttgc taattcatat
    21001 attgcatttg caaatatctt tgcatttaat attatatctt ctatatccat gtattcatca
    21061 ggattatgag ctattccttt ttgtcctgga aatgaaggtc caaacggaac tatatttggc
    21121 attacttttg catacgtacc tccattagtt gttacgggag ttccatctaa tgatgtaacc
    21181 ctttcataag ctagctgaag ctttttaaca agattactct ctttatcaaa atatacagga
    21241 ttaaaattag aaattacctc tatatcgata ctatttggaa aactagcttt tatttcatcc
    21301 aatacatctt tcaatttata actaaaatcg tattttacct ttatatctaa tatagtatca
    21361 ctattttcta tattcagctc tttatatgta acaagcacat tttcagacat attttctata
    21421 aaacctaggt atacatcttc ttcataattg attttacttt ttattctaat ctttgccatg
    21481 cctttttcac catatacaac aggatattta caatctggtg taaatcccat aataggtgct
    21541 ttttcttttt ctaaataata tggtatatct tcaaatccac tttcttcatt tgtaccaaat
    21601 attattctaa ctctcttatc taattttaag tttaattctt taatagcata taatccatat
    21661 aaggcagaca ttataggtcc tttattgtct agtactcctc gtccataaat tcttccatta
    21721 gtttcttctc ccttataagg ctgatgcttc caaccatctc cttcatgtac aacatctaca
    21781 tgtccaatta cacaaacata atcatcacta tctccatgct ctgcataacc aatataatta
    21841 tccaagtttc taaccttaaa tcccaatttt tctgatattt ctaatgcttt attaagtgcc
    21901 tcccctactt tttcgccaaa agggaagcca ttttctgact cccctttgac actaggtatt
    21961 tttacaatat ctataatatc acttaataaa tcttctttta actcatctat tttattactt
    22021 atgatattca taaaaatctc cttattataa aactctattt taattatgta accactactt
    22081 tactcactta cttctattgg tgcttttatt ctagcctcat atgcttccat ccactcattt
    22141 gatataacct tatgtatagt ctttccatct actctatttg aaatatatac agtaggagat
    22201 tcttctttag ttactactga aaaagtaaaa tcagctatat ttgtagctac tccccattca
    22261 cctttattat tcatggcaac taatgataaa tcaccagctt ttcctcttct tttgataagc
    22321 tgtttatcaa gttcatttac tgcaatatca catgcttctt gtggatgctt cccttctttc
    22381 ataagtctaa ctatctcata agatatacat cccttcatta aatcttctcc caaaccagta
    22441 gctgtagctc ctcctatact actatcaaca tagaatcctg aaccagatag tgcagaatct
    22501 cctattctac ctcttttctt cataaacaat ccacttgttg atgtagctgc acacattttt
    22561 ccagttttgt ctaaagatat cataccaaca gtatcatgac cagcatatgg gcttaatcct
    22621 ttgtctaaag tctctttttt tctcttttta taatgtaact tcgctctatc agtcaacata
    22681 ttttttcttt caaatccatt tttatgagca taatcttcag cacctattcc aactaaaaaa
    22741 ttatttacct tctcataact taacttccta gctatgctga caggattaga ataatctctt
    22801 ataccagcaa ctgcgccaat atctaatgtg ttaccatcca taaatgcagc gtcaagttct
    22861 acctcacaat tttcatttgg aagtccacca tatccaaccg atttatagaa tggatagtct
    22921 tcaactcttc ttacagcaag ctctacagca tcacctgctt ccatgccttt ttctaaatgt
    22981 tctgatgcct cagttattcc ttctagggcc attctccatg tcgctatcat tccccacatg
    23041 ttaaaattcc cctccttaaa ttatatagat tttactaatg tatgcttatt ataaatagta
    23101 taatatttaa acttgctaat aattaatact cttattgata acaaaactct tctttcatca
    23161 aagttatatc ttctttattt gctattgctt ttgccaattt acatatgtta tttaatgaat
    23221 cattaagacc aattccacct ttttttggag tcttaactat acatatgtca tttttatatt
    23281 cgtttatcac atctatattt tcttctgaca tagctgcaaa agctggtata tctgttttat
    23341 catttatatt tttagacagt attgctgaca tcttagaaaa gttttcgtaa ttaaagcttg
    23401 gtccacagat tactacatca gggtttaatt tttttaccat agctatcatc ttactcgtta
    23461 cttcttcttg attatttaca aaaaattcat ccccacaaaa taaggtagct attaccttag
    23521 attcatttaa aaattgctcc atcattacac ctggtcctaa tgggcttgat tttccagcag
    23581 gaggtatatt acttttctct tttcctccag ctccagcttg tatttggtcc aatatcataa
    23641 ctattttctt cataatcttc ctcctataat actaaatcat caaaagatat atcatcatct
    23701 tcctcttcaa cagtttcatt ttcttctctc aagtattgct tatctagcat ttttataaat
    23761 ggtatataca taaatattcc tagtataaga agtactaatt gtaagactgc accttgccat
    23821 cctgttgtta aaaaaccaga gaatataatt ggagttgtcc acggtaactg aactccattt
    23881 gtaagaggca ctaatcctgc tgacatacag aagtaagcta ttattatatt tattgttgga
    23941 actattgcaa atggtatcaa tagtattggg ttaagcatta ttggtagacc aaatatcaat
    24001 ggctcattta taccaaatat tcctggtaaa attgatagtt ttcccattga ctttatacgt
    24061 ttacttttac atattaataa catagctatg actaatgata gtgtactacc tgctccacca
    24121 aatgtcgcaa acatatcttg gaattgacct gttattatgt ttggtatttt tgaaccagct
    24181 tgaaaagcag ctaagttttc agctgataga atttttaata ttggattata cacagcccca
    24241 acaacactac ttccatttat tccaaagaac cagaataaat gtaagaatat ataagcgatt
    24301 gccatagcac ctaaactatt tcctaatttt aataatggca tttgtaaaaa cttaaatata
    24361 aattcatgta tacttccata tggtgtagct tcaaaagcta tcttaactaa aaagaaaact
    24421 accataacta ttgcacttgg tattaatgct gcaaatgatt ttgatacagt tggaggaact
    24481 ccatctggca ttttcaatgt ccatcctttt tttacaactg cagcaaataa ttttacagag
    24541 gttattgctg ttatcatacc tacaaacatt cccttagaac ccatccaacc tagtggtata
    24601 cctgttacca tgtaaactga ttctgttcct tctggtgtat atggtattac aaatggtgtt
    24661 attataaaaa aggcaactat tgcaactgct gctgatgcta ttgggtctac atctatttgc
    24721 tttgcataag aatatccaat ccctaaaact gcaagtagag tcattacttc aaatgttgct
    24781 acagttggtt gttgcaattt tacagcccaa tctggaccaa aaatttgacc tacaaattca
    24841 ttccatcctt ttataggaaa atttgctact aataaaaata atgaacctat tattaataat
    24901 ggtgatgata ctaaaaaacc atctctaatt gcaattaata atttattttt acctattttt
    24961 tcagccaatg gcataagtat tctttccaat ctattcatct atccaccctc atttcctatt
    25021 attttttact ataattctac gcttgtttag attttattag ctttatagca agttttaata
    25081 ctttttcccc attcatagtt ccataatcaa cttcattgat tatatctata agttttcctt
    25141 gagcttcaaa ctttggtttt aactccttta gcatgtattt aacttgtggt cctaataata
    25201 tacaatctgg atttttttct tcaactattt tgtcaatttc tgctatcgga aatgcctcta
    25261 cttctattgg taaattgtgt tcatctgcta ccttctgcat tttatctgca agtaaacttg
    25321 ttgacatacc aaagctacaa aataaatata cttttctttt cattttttaa atccccctta
    25381 atttttttat tttaattttt gaatttcttt tcttaacata atcatttctt ttataaggtt
    25441 tctctcactc atacaagtca ttaaatggtc ttgagagtga atcaataaaa tagatatatc
    25501 tgatttatct cccccagctt ccttttgtat aagttcagtt tgtactttat gtgcttttaa
    25561 aatttcttca tttgcatttt caattaattc atctgctttt ttaaaatcgt tttcctttgc
    25621 atagtcaagt gcttcataaa gcatagattt tgcatttcca gcatgaatta taatctttaa
    25681 aactatttct tccatttttt cctcctaagt tgcttctcta cttttagatt atttatacct
    25741 tacaaacata taatatctta taaaaacaaa aaaacatgca caactttttc catcacatgg
    25801 aaaattttgt gcttatccat agttcactat gaattttata taagaatatc ttttaccttt
    25861 tcaatgtcac atttacttag aatatctagc atattttcat cctctgttaa attagatatt
    25921 tctttaaata attctctaaa tacttttcta tcatcatctt ttttatacgc taacaaaagt
    25981 ataatcttta tatcctttcc atttctaatt tttattggtg tttttaacct tgcaaaacat
    26041 aaaacagatt gttttatata tttcatgtct ccatgaggga ataatattcc ttttccaaca
    26101 ttggttggat atgacttttc tcttgttata atagattgta aatactcttt ttctgcataa
    26161 tgtttttcaa ttaataaatt agttaaatat gttatagctt cataaatatc atcatgttct
    26221 aactctctta ttaaataatc agacatcatt aatctgttca taagtttata tgaagtgtct
    26281 ttttctttta ttttgtttgt gaactcttta agtttattct catcctcatc agtaaataat
    26341 ggtgttgtta taaaaattgg tttttggata ttttcatact cttgaaatgc aattataaaa
    26401 tctatagtct tattaaagtt atctcttttt aaatcttcct ctcttaatgt ttcaataatt
    26461 tttatgttat caaatctctt ttctatcttt acttttaata gcatacttac tccaaaacta
    26521 aatggacata caatacttgc ctttttattt gattcccttt tgctgtattt tctttctaga
    26581 gaggtttgaa agtgaagtgt aagataacca atttcatctt ccgttatttg ttttcctttt
    26641 aattcaattt ctattgaact tgatattact gtaaataaaa aacaaaattt agtttttatg
    26701 ttatctaaaa gtggattttc taagtaaaca ttgcttttca tttgatgcat tgtaacattc
    26761 aaatgacata ttaattgttc ataaagtaat atatcattat taaaatttat tcctgattct
    26821 tctgatacta aatttataat tttttttgta taacttgcta attcttcatt tagatataaa
    26881 gatttcttaa tattattact atttatttgt ttgttcatac ccaatattaa agattctata
    26941 aacaattttt cttcataatt taatactatg gataaattag atttcaattc atcttctata
    27001 tccaatataa gcatttttag cttaagctct ttcttagtat ttgatacttt taaagaattt
    27061 cccagcctta ttcgtattat atttataagc aaaaatagca tcaattgctt gaatgatata
    27121 tctgtaagtc ttatatccat atcctcttct atagtaagca ttatgttttt tacaattatt
    27181 atatctacta tatggaagta ctctatttca tctatgttta atctgtattt atctatatat
    27241 ttaaataaga atgatactaa cattattctt atgtctttct catccccttc aatatatata
    27301 ccactgcctt ttttagtcga gatatttaaa ttataattat ttaatgctac tgataattta
    27361 cttatttctt ctctgacaat atttttattt atgtacaact tattagataa atcatttaaa
    27421 gtaacttttt tattattaca aagtagtaaa tttagtatct caacttgctt atgaagctca
    27481 ctatttactc ttttaacttc acctcgcaac ttctgattta ccagtatttt gtctgttcca
    27541 tctccactaa atttaatccc aatattaggt tttcttttga tataagcatt acaaaaagta
    27601 gataaccatt catcaatata tttgcaatca tttcttattg tcctttctga acactcaaaa
    27661 tcattggcaa tcttattaac atttataaac tcttctttta atagcaatgt tgttaataaa
    27721 ttttcttgtc ttttattcaa acatatcacc tctttatgac tcaacctaaa tttattatat
    27781 ataaaaaaga gctatacata aaggtatgct agctctcttt taatatgata tttagctgac
    27841 ctggtttttg accccacact cgcctactgg agggttcgct tgggttcgcc gcactactac
    27901 tctctctcga ttttattatc ggtaggtctt acttctaagc cgcaccatga tcattaaccc
    27961 aatttttagt gttaacttac gtggatccct ttgcctgcga ctggcttgga ctttcaacca
    28021 cagacctaaa tatcacttat tcattttaat attttaaact aaaattgtca atatataaga
    28081 ttattccata atataattat catttgcttt tgtaagtaga gtcaatacaa aaaccttatt
    28141 agcacctgat aactttaaaa gtttagaaat ttcgtttgtt gttagaccag tagtaaatat
    28201 atcatctatt aaaagtatat ttttattatt tattaattta acattttctt taacaacaaa
    28261 tacatttttt aattcttctt ttcgttcttt cttattcaat ttatatagca ttcttgtata
    28321 tttttttcta cttatgcaat ctaataatgg aatatttact attttactta aattaaatgc
    28381 tattttttgt gcctgattaa aacctctttt atttagcctt tttttatgaa gtggaacaaa
    28441 taatatataa tcaaatttta tgttttctaa atataatttt tctttcatta tttgagctat
    28501 atacttagcc ataaaggttt tttggttata cttcagccct aacaccatct tttttgtcac
    28561 atcattgtat tcaatacaag atattgattt atcaaaataa aagtctttat taaaacaata
    28621 actacactct tcaataaatt ctttttcaat tgaatgacgt attattggtt ttccacactt
    28681 catgcaacca tcttgtataa aattcatttc tttaaaacaa cttttacata ttgaataagt
    28741 atttgttttc tttatggatt tatcacaaat tatgcaactt atattctcag gatatataaa
    28801 atccaaacat ttattaatca tatttttaaa attcttaata aaattatcat tgcatatttt
    28861 catatttatt ctatcaacaa cccttcttgt ttaaatttat ttagcttata tcctaaattt
    28921 gaataccttt gattaactct attatttttt atcatatatt caagatattt cacatctcca
    28981 actaatacaa ctaatttttt tgctcttgtt actgctgtat ataataaatt acggctaagt
    29041 aacataggag gagcccacgc tattggcaat actacaactg gaaattcact tccctggctt
    29101 ttatgtattg ttgtacaaaa actatgatca atttcatcta attcatcata taggtatgat
    29161 acaattttag tctggtcaaa taatatataa atagttttct tatctttatc tatgtgataa
    29221 acatatccta tatctccatt atagatacct tctccacttt ctttttggtc ttctgtttcc
    29281 catttttttg tataattatt ttttacttgc attaccttat cgccaactct aaataatctt
    29341 ttagaaaaat tttcttcaac tttaaatttt tcttttttgt taagatactt ctgtaactct
    29401 atatttagat tagtaactcc caattcacct tttctcattg aagataaaac ttgtatatct
    29461 tttaatttat caactttata aaatttaggt aatctttcat taaccaatcc tattatttca
    29521 tttaaaattt cttcattagt tgattttctt ataaaaaaga aatctttacc ttttgtattt
    29581 agataaagtg gttctccatt gtttatctta tgggcattta caattatcat actttcttgc
    29641 gcttgtctaa atatttcatt taatttaact acatttatga tattagaatt aatcatatcc
    29701 ttaagtacat ttccagcacc tacagaaggt aattggtcac tatctccaac taaaattact
    29761 cttgttccta actttatagc tctaagtaaa ttgtacatta agataatgtc taccattgat
    29821 acctcatcaa caattattac atctgaattt attgggtctt cttcatcctt aaaaaaagtt
    29881 aaatcatcat ctgttgaaaa tcccatttct agcaacctat gtatagtttt tgcttcttta
    29941 ttagaagttt cactcattct ctttgctgct cttcccgttg gagctgccag agtcacactt
    30001 ttaccattat tttcaaatat atctatgata gcattaatgg tagttgtttt accagttcct
    30061 ggtccaccag ttataattaa tactccacta ttaacagatt ctttgactgc taaaatttgt
    30121 ttttctgcta acttaatttt cttatcttct tctaaaacat taatctcgtt atctatatct
    30181 atttttaagt cttcaaattc atactgtgat aattttacta tttgactaca tactccattt
    30241 tcagctaaat agtatggcat aaggtatata agattttcat tgtttacttt ctctatatgt
    30301 attttttgat tataaactag catcattaca cactctttta ttatttctcc atttagctcc
    30361 aataattttt ccgaatcttg tattagaaca tgctctggta aatatgtatg cccattactt
    30421 aaagatttat ttaaagtgta taagattccc tgacaaattc tatctttaga gtttttatct
    30481 ataccaattt tacttgctat actatcagct actttaaatc caattcctct tatatcttca
    30541 gcaagttggt atgggttttt atttataact tctattgcac tgcttttata ttttttatat
    30601 atttttaggc agtaatttgg tgttattcca aaaggagata gctgtattat tatatttctc
    30661 aattctctgt cttcttcata actttttact atttgtttta cttttttact ccctatacct
    30721 tctacttctt gtagtttttc tggtgaattt tgtatcacct ctaacgtatc tacaccaaac
    30781 ttatcaatta ttctttttgc cattttttca ccaataccat gtatcattcc agaagataag
    30841 taaacataaa ttccttctaa ggatgatggt gttactggca taaaactatt cacttcaaat
    30901 tgagtcccat aaatcttatg atttacccac tttccttcaa cttctatgct ttctccaatt
    30961 gctaaagtag gcatacatcc tacaaccaca atttcatcat tttcatttac caggtgagct
    31021 attgtataac cattatcttc gtttttaaag actatttcac ttatcattcc ttctaatttt
    31081 tccattttta tctcctaaaa atactaataa tcgctccatt taaatgttag tataatttta
    31141 tatattaaaa ctatgataat cgtagaaaag ttttatattt ttatacttaa cgtaatttcc
    31201 aactattata cattttatca gaaacaaaaa aaatctgcat ccataaaata tggtaccatg
    31261 aaatacaggt accatattta aatagctatt ttattttaat tactctatat ttagagtata
    31321 aattaaattt cataagtata ttacagtact aacttatttc agatttattc tccttgtacc
    31381 cctcagtttt agtaattctt ctataaagca tacatagtaa aattaaaatt cccatgtaac
    31441 ctgtatatgg atatagtgta cctactaact tatcaaatgg cagtaaacct cctatacaag
    31501 ctaatatact taccactatt gttataattt taaacttagg gtggtcatct tctacaaatc
    31561 ggtttgttac tgaccataac aatggtacag ctgtagtgta tattcctagt aaaagtacta
    31621 ctgagaataa aatacctatt attggagata tcttatcagc taagtaaagt gctggtatct
    31681 cttttgtgta tatatttcct atgtctgaaa gtaatgccaa attcatcatt atagctgctg
    31741 ccataagtgc tactccacct actataccac cccatacagc atctttctta tttactgcag
    31801 aagctcccat tcctgtcaag aatgttatta ctattattac attgtaacaa gtataaagta
    31861 ctcccgagaa atatccattt gatgtagcag ttttaatatt taaactatca accatatttc
    31921 cagcatttga taaagcatca atattgctaa ataaactaat tgctcctact aaaagtgtaa
    31981 atattattat tataggtcct atattaccta gtattttaga aagccttgtc aaacctaatg
    32041 aaacagttat tagggaaacg attgccatac caatcctacc tacatatgga tttaatccat
    32101 agtactctga taatgtagct cctgctcctg caatcattat tactaatgtt ccaaataaaa
    32161 acaatggacc aaaccattca aaaaatgttc caagatattt tccacaatat acttgataaa
    32221 tttttattgg ctccttaagt ttcaattctc ttcccttatc tataacttct gctccaaacc
    32281 atgaaaatag taccatagag attattccac ctataatacc cgcatatcca taaaacgtaa
    32341 aaaattgcag tatttcttga ccagttgcaa atccagaacc tattacagta gcaacataag
    32401 ctccagcaaa acttataacc gttttaatat ttactttgcc tgacatacac tactcccccc
    32461 aattaaaatt atttttaaag tgtaagttta ttaagattat attagactca ttattgtgat
    32521 atttcaatat atttttaatt atttaacatt agttaacaca ttcttaacca tcctttaaca
    32581 tatatcccat aatatgtata aatttagtag agtattatat aaaatgtatt gaccagatta
    32641 aatactgttt attcattata tgatgataaa ttaacattta ttaaaaatat ttaactcata
    32701 ataaaaaagc tgttagaaag taatcgtaaa attacattct aacagctttt tagttaaaaa
    32761 ttattcacct aaagcatctt ttcttaactg ctcaaccttg tcagttcttt cccaaggtaa
    32821 atctatatca gttctaccaa agtgaccata agcagcaacc tttttataaa gaggctttct
    32881 taaatctaag tctcttatta tcgctcccgg tcttaaatca aagtgtttat ttactaattc
    32941 aacaagtttt tcttctgaaa ccttgcctgt cccaaaagta tctataaata tagataatgg
    33001 tctagctata cctatagcat atgcaagttc tatctcacat ttgtctgcaa gaccagccgc
    33061 aacaatattt tttgcaacat atctagctgc gtaagcagca gatctatcaa cttttgtagg
    33121 gtcttttcct gagaaagctc ctccaccatg tctagaatat ccaccataag tatctattat
    33181 tatttttctt cctgtaagac ctgtatctcc ttgtggtcct cctataacga atcttcctgt
    33241 tggatttata taaattttag tctcttcatc aagtaattct gctggtataa cttccttaat
    33301 aacatgatta attaaatctt ctcttatttt atcatttgat actgtttcac aatgttgagc
    33361 tgatataaga actgtatgta ctcttacagc tttacttcct tcatattcaa cagtaacttg
    33421 agtttttcca tctggtctta aataatcaac taaacctgtt tttctaactt ctgtaagtct
    33481 tcttgataat ttatgtgcca aagatatcgg aagtggcatt aattctggag tctcattaca
    33541 tgcaaatcca aacattatac cttggtctcc agctccaact ttttctattt cttcttctat
    33601 ctcttctcca gtcttacttt ctagaccctc atcaactccc atagctatat ctccagattg
    33661 ttcatcaata gaagttataa ctgcgcaagt atcacaatca aatccatatt ttgctcttgt
    33721 atatccaatt tctcttactg tttctcttac taatttagga atgtctacat aagcagatgt
    33781 acttatttct cctgctacta aaactaaacc agtagtaact gtagtttcac aagctactct
    33841 agattgtggg tctttttcta ataatgcatc taatattgaa tctgatattt ggtcacatat
    33901 cttatcagga tgtccttctg taactgattc tgacgtaaat aaatgtcttg ccatttttat
    33961 tcccccttat ttattcttaa tttttattat aggttttacc ttgtttttaa ttttagaaat
    34021 ttactcaaaa taaaaaaacc tctcctttat aagaagaggt taataatcgt aattacatac
    34081 taattaactg acctcatctt tcaagacttt tgtcttgtag gaattagcac cttttcccat
    34141 ttgggtggtt gctgggcttc acagggccta tccctcagcc tctcttgata aggtaatcaa
    34201 gatttaagtt ttgttttact ttactagctt actatttttt taaaattttg tcaatatttt
    34261 tagtcatatt ttttctattc ctttttttgt aagacaaata aaattttcta tctatctgaa
    34321 atttaaagtt aggtcttttt aatgcttttt attcatatat ttttttgaag ggggtgttcc
    34381 tattgtattt agctaaagta aactacagcg atgatgatgt tatacagatg ctaagttcag
    34441 ttctaaaaac tataattaat gaaaatacga ttgttgtttg cataggaaca gacagggcta
    34501 taggtgatac tttaggccct ttagttggaa caatacttaa gaacagtaac tttaaatacc
    34561 ccgtttacgg tacactagat aaccctattc acgccttaaa tatatatgag tctttagata
    34621 ctataaaaaa tacacatata caaggtaact tcttggctat agatgcttgc ttggggtcgc
    34681 agagtaacat aggtaatata cagattagag aaggacctat cctgcccgga aaaggtgttg
    34741 gtaaaaaact acctcaaata ggaaattatt ctatagtagg aattgtagat aaaattgatg
    34801 aaaataataa actttcattt aataatatac gccttagctt tatattagat ttagctgaaa
    34861 caatagcctt ggctttatta gtatccacct aatctaaata taaactaaat gataaaattc
    34921 tttatataaa aaggtagata ttttagagta tctgattaaa tactccaaat tatctacctt
    34981 tttactttta tatttcaagt ttttattttt ctactaaagc aaacattaat tcacctttac
    35041 agacaagttc ttcacctaca tatgccttag catctgcctt agctatattt tttctaagag
    35101 ttgtcatttc aacttccata gttaatgtat ctcctggtct tacttctctc ttgattctaa
    35161 ctttatctat acctgcaaat acacctagtt ttcctttgtt ttcctctaca gacatcattg
    35221 ccactccaca tacttgtgct agagcttcta ctattagtac tcctggcatc aaaggatatt
    35281 ctggaaagtg accttggaaa aatggttcat taactgttat attctttata ccaacagctc
    35341 ttttcccaac ttctagctct gtaatcttgt ctactaataa aaatggatat ctatgtggta
    35401 ttaatttttt tatttcatct atatttaaca ttctaaactc tcctaattat tttcttttga
    35461 aagacccacc agtttcaagt aagtctattg aacctaaagc tattcctgta ccttttgcaa
    35521 cacaagataa tggttcatct gctattgtaa cagttattcc tgtcctctgt tctattattt
    35581 tatctaatcc atataataat gaacctcctc cagtcattat tataccgaca tctcctatat
    35641 ctgctgctaa ctcaggaggc gttttttcca aaacagcatg agtagcaact actatttgct
    35701 caacacattc tctaagtgct tccaacattt ctgttgaatt tatagttata gaactaggaa
    35761 gtcctgtaat taaatttctt cctgttatct tcatatattt ttcttcttct ctcttaaatg
    35821 cagaacctat ttcaaacttg attttctctg ctgttctttc tcctataaga agattgtgtt
    35881 gttttttcat atatttaact atagcatcat caaatctatc tccaccaacc tttatagatt
    35941 cacttacaac agctcctcct agagatatta cagctatatc tacagtacct ccaccaatat
    36001 ctataatcat attaccatta ggctgtgata tgtctacacc agctcctatg gcagctgcta
    36061 ttggttcttc tatgatatat acttctctag ctccagcttg tctcgtagca tcttctactg
    36121 ctcttttttc cacttctgtg acacctgttg gtacgcatac cataattctt ggcataaaaa
    36181 atcttccaaa tcccttttta tcaactatct tatctataaa agattttaac atcttctcag
    36241 ttacatcata atctgaaatt acaccatctc ttaaaggtct tatagcgact atattacctg
    36301 gtgttctccc tatcatcttt ttagcttctt ctcccacagc taaaacagaa tctgttcttt
    36361 tgtctatcgc cacaacagat ggttcttcta aaacgattcc cttaccacta acataaacaa
    36421 gcacatttgc agtacctaaa tctatgccta tatcagctcc agccattttt tcaactcctt
    36481 tatttataat attagattat attataagcc tattttaata ctcctataat aaagcatata
    36541 caaaaatctc gctttaatca agagaaaata aatcttttga gagtattatt attttgctat
    36601 ttataattac ttaatatatt tctttttata atttaattca ataaaaaaag taggttttta
    36661 acctacattt ttttatgttc cttctcatat tttaatttcg ttgctaatcc ccctctaata
    36721 tgtctctctg atttattttt gtccagcaca tttttaactt ctttggcaag ggatggattt
    36781 atttccttca atctttctgt aacatcctta tgaattgtac ttttacttac tccaaatgtc
    36841 ttggcggttt gtcttactgt agtgtttttt tcaagtatat attttgctac cactatggcc
    36901 ctttcctcta tatgagatct caaagattac ccccctcaca taatagcttt aatgatatat
    36961 atgtaaaaac accaaaaaat ataacaagct taaccaaata tgattaaact tgttatacta
    37021 ttacttaatt agactcattg ggtctataga tttttctcca ctatacgcct ctaaatgcac
    37081 atgtatacct tcttcacttt ctatttgaga agtactacct acagtaccta gagattgtcc
    37141 ttctgttacc ttctgttctt tcttaacact aacattttta tctagatttg aatatactac
    37201 tacaatgtta ttgtcacttt ttattttgac tgattgtcca tattcttcat catcaaatac
    37261 atctactact attccgttta atagagattt tacttctttg cctttagtac aactaatatc
    37321 tacaccttta tgagtttccc aaacatcaag tgttttagaa taactaggct ctttttctga
    37381 atatcctctt attactttat ctccaatgta atttaatttt gttgtactcg atttattttc
    37441 ctcttttgac ttagcttttt ctaagttttg ttttgaatcc gttgcagtag ggatagcatc
    37501 tttcttgtct ttttcaatta aatgtatttc ctcttcacta tctttattag cattttccat
    37561 aattccttta ttagaagcca atttatctac attattattt gtaaaccaaa ctccacctac
    37621 tgctaataaa caaacacata caaacaaaga taaataaaaa ccatcttttt ctaacagctt
    37681 tttcttcatt ttgcacctcc aaatatattt ctacatttgg attattgacg tgtttttggc
    37741 attttataca attattagta tatatctttt atttttgtat ctgtgtagta atgtgataat
    37801 atatcataat atttataacc ctcttctgcc attccttctg ctccccactg gctcatacca
    37861 acaccatgac catatccttt taccacgaaa tctatgtatc cttctccaaa ttttatgtca
    37921 aagtttgcag agttcaactt aaaaacagtt ctaatgtctt ttccagtcaa ttctttattt
    37981 cctaatttta ttttttctac agttccggca tcacttcttt tagttattga aacttgttta
    38041 cttaaattat tcacatctat cacaatagtg ctatatgccc ttctaagact tttaacaaaa
    38101 tctgtgttac ttattttaag tgttgacgca aatttagggg aatacttatc ataaggactt
    38161 tccacagact ttaaataagg atattttgca gaaaatactt cttcactatt ttctgttttt
    38221 cctgaagatg tagaaaaata aagaggaagt atcgccttat cattataagt tattatttga
    38281 cctttagttc ctctaactgc ttcttggatt ttggaatatt tattcttaat ccattcttca
    38341 ccatttaatt ttttaagagt atcataactc ttatattctt gacaatgttt ataatcagta
    38401 catactactg catttttatg tttactagat ttaccatgtt cctgtttata tactacatat
    38461 gttctagctg ctacagattg agcttttaaa gcttctatat caaactctga agacatctca
    38521 ccagctagta ctccacataa atagttctcc atgtccatct tttcggtttt ccctgttata
    38581 tgattatata cattgataat tggtgctttt ttatttacag tttcatagtt cactgtattt
    38641 ttttcttctt tattaccttt gtcttcaata tcactttttt taatagtttt gtttatagat
    38701 actgggctct ctggtttttc agttaattct acatttttat aagaaactaa agttataagt
    38761 gatggaacta acacagagca agtcacaaat cctaacaaaa caaccaatgg gttcttcata
    38821 tactctcctc cttagctttt aaaaccttgt atttaagtat atgaacaacc ctattaattt
    38881 ataactttct tctataaacc aattattaat cttctactat ttcgatttga ccacctagtg
    38941 ctgttatctt cttatctata tcaacataac ctctttggat atggtatatt tctcctattt
    39001 gagtttctcc ttctgctata agaccgcata aaataagggc tgcccctgct cttaaatcag
    39061 tagcgtttac tgctgcaccg tgtagctcat ctacaccatt aacaaccgca cttcttccat
    39121 ctatttttat attagcaccc attctattaa attcagcaac atgcataaat ctgttttcaa
    39181 aaacagtttc tataactaca ccagttccat tggctacagt aagcatagcc ataaattgtg
    39241 cttgaacatc tgtaggaaat cctggatgtg gtaaagtttt tatatctatt ggttttaata
    39301 cttttggacc tacaactctt acagaattgt ccatttctgt tatttcacaa ccagcttctc
    39361 ttaatttagc tacaactggt tttaaatgct ccattaaaac attttcaaca gttatatcac
    39421 cttttgtcat agctgctgca accatataag ttgctgcttc tattctgtct ggaattacat
    39481 tatgttctgc tccttttaac tctttaacac cttttatttt tatagtatta gtacctgcac
    39541 ctttaacatc tgctcccatt tcgttcaaga agtttgctaa atctactatt tctggctctt
    39601 ctgctgcatt ctctattatt gtagtccctt ctgctaaaga agctgccatc attatgtttt
    39661 cagttgctcc aacagatggg aaatctaaat ataatttatt tcctactaac ttttctgttg
    39721 ctgcttcaac aaaaccatgg tccatttcta tctttgcacc taaagcttta aatcctttta
    39781 aatgtaaatc tataggtctt gttcctatag cacatcctcc tggcatagaa attttcgtac
    39841 tattaaatct agcaagcaat ggtcccataa ccaaaaaaga agctctcatc tttcttacaa
    39901 gctcatatgg agcttcacaa gtttttatat tgcttgcatc aacagtaagt gtattttctt
    39961 tatattcaac ttctgctcct acatgtctta ataaatctga tataacatga acatctctta
    40021 aatttggtac tccatttaat gttgattttc cgtttgctaa taaagtcgct gctattattg
    40081 gtaaaactgc attttttgca ccatctattt taacactacc tttaagtgga ttactctttt
    40141 ttactattat cttagccata ttttttgatc tcctcataat taataatcta attttataat
    40201 tggtgtggca atatatatga gtgtttttcc gtcatcctca ttatatttaa ttcctatatt
    40261 taaattaatt ttttccccta aatattctaa ttcataatca tttaatactt tactatatgc
    40321 tgttatagat aaaaagttta cgtctttaac ttcatctatt tgcttagcac tcatattata
    40381 taatattttt tgtaaaatat catcatattt gttgttttgt aacctttttg tgtattctcc
    40441 aacaatacaa gcagacacat ctacttgaga tgaatattta tttaacacat tttctacgtt
    40501 actataaata acctctttat gtttatatac tttgttatcc aatatgtcaa ctactatgta
    40561 actttctttg ttatttttat ttattccttt tatagaaatt tctttatcgc taccttttat
    40621 agtagcacat aattgtattt tatcgccaga ccctttttga ttccaattta ttcctttttt
    40681 atccaacttt agattgttaa ttatttctat aaaaatatta tgaaattctt tatttgataa
    40741 attatgattt ataacagaat taattttaac attataaaat ttaaaatttg cttctgatat
    40801 ttcaagagct ttacttaatc tattgtatct agtatttata cttgtatctg cataagatat
    40861 tgtcattcct ataatcatta atataaaaaa gcttatagct aattttactt ttttcatagt
    40921 aaaaaatccc ccttaaatat gtttttctgt ataatagaat tattaacaaa tttaagagag
    40981 atatactttc tcaatatgta tttttataca tttttgtatt tttcatctaa taatctcttt
    41041 caaactcttc aatctcaatt ttctctatcc ttctcctgga cttgccaatt tcttatatgt
    41101 atcaaataca tcttgcatta attcttatat attctcttct gtaatataaa ttacttagtc
    41161 tatacttaaa tctataatct ataatctata atctataatc tattcatatt ttaccaacaa
    41221 aataaacaga taatactttt ttatcaattt ccatagctcc aaatgaacat acctaagtac
    41281 acttcccaat acacaattta cacactcttc ctaataaatc aaaaacacct ttgttttaaa
    41341 caactctatt gcactttcaa aaactttatt tgtgttctcc cacttcaatt aaatttgaat
    41401 tatcaagact ccagcccatc catccatcac tataaaggga ggtattttcc actcctatga
    41461 catttgcata tgttaatact tcagcagcac gccatccact tccacacata aatataagct
    41521 gtttattcac atctatattt tccttgtccc acatttctaa aatctcatat ttatttctca
    41581 ttgtattatc aatattacga tattcttcta gtgaaacact atcactacct gaatgtccat
    41641 ataaagctcc tggtatacgc ccttttttat cataatatgt atatccagat acttttccta
    41701 tatgttcatc ccaagtacgg ttatctacta gtataaactt atttttttct tttagttttt
    41761 gtcttaattc agatgtagta acaattaatt gtgagttaac tggtatatct gctccaaaat
    41821 tagtacatga atgttttgga ttactaataa attctaattc atatcctgct gataaccatg
    41881 agtttgttcc accattcaaa actcttacat cttttactcc tatatatctc aatataacag
    41941 ctagtctata agatgccata ggtgtactac ttgaaactat tacagtatca tcctttgtta
    42001 atccatagtc taaagcaaac ttagttaagt tatcatcatt atcaagcatc catgttggag
    42061 gaggttctat aatatcagta tttacatgaa cacttgtagg tatatgccct tttgtatacg
    42121 attcttctct ccaactcgct tcaatcattt ttatattctt tgaatcttca aatgtctcag
    42181 gaatttttcc atctaatata tcttttatta taaaagcagg aactatcatt tgataatttt
    42241 tatatctttc cattggaaga ttttcgtcgt ctgcccattg tttaatatca tatttatata
    42301 gatatttata tcctttttta gataaataat ctgctacaac caaagcatct tttccatttg
    42361 catcatacaa tactatattt ttatctaaat caattctttt agttttcaat gcttgttcta
    42421 acacttcatc ttttctatct gagtatacac ttaaccaatt agcagaaaaa tctactgctc
    42481 cttttatatg tccacctctt tttactccat ctaacttcca gccattataa gcatcattta
    42541 agcgagtatc aactataacc caagcgttat cttgcacttt ttcttgtaaa acttcagtag
    42601 atattgcctt aagattaaca aaataatctt ctttcttttc ttttttaaaa tcatttgtca
    42661 taatttatac tcccaattta aaaaaatttt tatttgaaat tattttacta aaataaagta
    42721 attttcttat actctattag cttcattata ttcttttata aatagttcct tatattctta
    42781 ttttaaacta ctcactttat cttatcacaa ggttactaat accttgtatt ttaatttttc
    42841 tcataagcta ttattttttt atctgatatt gactatatgt ttattaagta ctcactatat
    42901 tttatatgaa ctatatttat cgttccctat acctggtatg gtctatatat ttatcatttt
    42961 acagatgatt taatatcaat ctttttataa aatttattat agcaaaaaca aaacaaattt
    43021 aatatttatc taaaaaactc atcctataaa atacaaataa caggatgagt tcttttcaat
    43081 aaatattatc tatttaattt ttaatctgtt tttattcaac tgttactgat ttagctagat
    43141 ttcttggctt atctacatcg catcctctta gtacagagac atgataagca agtaattgca
    43201 ttggtacaac tgctaatatt ggtgataaaa tatcatctga atttggtata tagattattt
    43261 tatcagcagc tttctcaaca tccttattat ggctttgagc tattgctact acataagctc
    43321 ctcttgctct tacttcttcc atattagaaa ccattttttc aaataacttt tcttgagtag
    43381 ctatggcaat tacaggagtt cctttttcta ttaaagctat tgttccatgc tttagctctc
    43441 ctgctgcaaa agcttctgca tgtatatatg aaatctcttt taatttcaat gaaccttcca
    43501 ttgctaagct atagtctata cctcttccta aatagaatgc atgttcagaa ctaacaactg
    43561 ttttagcaac ttcttttata tattcttcat tgtctagtat ttcttgtatt tttgatggta
    43621 tttctttcat cttagaaatc atactatcat aaaattctct agttattgtt ccttttttga
    43681 tagcaaagtc taaagctatc atgtataaag aagttatttg agtagtatat gccttagttg
    43741 atgcaactgc tacttcaggt cctgcccaag tatagaatac atcatctgat tctcttgcta
    43801 tagatgaacc tacaacatta gttattgaaa gtattcttgc tcctttagcc tttgaatctc
    43861 ttaatactgc tagagtatct gctgtctcac cagattgact aactaatatt actaatgaat
    43921 tttcatctac aaatgggtcg ctatatctaa attctgatgc tatatcagtt attactggta
    43981 tatttacaaa tttttctatg gcatacttac caagtaatcc agcattatat gctgttccac
    44041 aagccactat ataaacttta tttatttttt ctaagtcttc tttagaaata tttatactgt
    44101 ctagaattat atttccatta tcatcaagtc ttctttctaa agtttctctt actcctgttg
    44161 gttgctcatg aatttctttt gacataaagt agtcatatcc acctttagac gcagcttcta
    44221 catcccaagt tacatgaaat acttcttttt caacaagatt tctattagag tcataaactg
    44281 ttacattttc gtcttttaga tgaactactt ctccattttc taagaaataa acatctctag
    44341 tatattttaa taatgcaggt atatctgatg ctataaagtt ttcaccttca ccaacaccaa
    44401 ctacaagagg actatctttt cttactgcaa ctaattcatt tccatgttct ttacatataa
    44461 cacctaatgc ataagctcct cttaattttg atatagtttt gtatacagca tctaataaat
    44521 taccctcata gtatttatct actaaatgtg ctattacctc tgtatctgtt tgagattcaa
    44581 acttaacacc ttcagaaatt aattcttctt ttatttccat atagttttct attatcccat
    44641 tatgaacaac tgctattgtt ttggcttgat taaaatgagg atgtgagttt acatcagatg
    44701 gttctccatg agttgcccat ctcgtatgcc ctatacctaa atttccatca ataggattct
    44761 tttctaagtc ttctgcaagt acagaaagtc tacctttaaa ctttctaata ttaagttctt
    44821 tttcattaga actattaact gctactcctg ctgagtcata acctctgtac tctagcttag
    44881 aaagcccttc tactataact tctgctgcct ttctacttcc taaatatcca actattccac
    44941 acattatttg tgtcctccta aaaatattat ttatatattt taagagttag gtcatataag
    45001 tttactttgg cttccctttg tccataggat tgctcctatt atttaaagaa gtctttcgat
    45061 ggtaaacaca ccgcagagca tccgccgaca attcgattaa ctctgacctc gtcaacttag
    45121 ttcctatatt actcaataat tatgtctata actaagttct ggcgcttaga aaggtgtcct
    45181 cagtatttat atctgagaat accctttaaa ttacgataat ttttcttgta taagattagc
    45241 taagtttgtt gctaattctt ttatttgacc ttcctcttta ccctctaaca taactctaac
    45301 taatggctca gttcctgatg gtcttatcaa aactctacca tttccgtcta aaatagattc
    45361 tattctttct atctcagttt ttatttctgg atattccata tatttgttct tattttcatt
    45421 ttttattgtt gcatttacta atacttgtgg gtattggctc attattgatg caatttctga
    45481 taaaggtttc ttttcttgca agattatatt tgcaagtatt agagaactaa gcactccatc
    45541 tccagtagtg ttgtaatcta aaaatatcat atgtccagat tgctctccac caagattata
    45601 tccattttta accatatctt ctaaaacata tctgtctcca actgctgtag tagataaatt
    45661 tattccattt tccttagcag ctattgtcaa ccctatatta ctcataactg taactaccaa
    45721 agtatcttgt gccaatttat tatttttctt taaatttaag gcactcaata tcattatatg
    45781 gtctccatca acaatttgac ccttttcatt tactgcaatt aatctatcag catctccatc
    45841 atatgcaaga cctaagtcag cattatgttc caaaacagcc ctttgaagtt gttctggatg
    45901 tgtagagcca catttatagt ttatattatt tccatctggt gaactattta ttgaaattac
    45961 acttgctcct agttcatcaa acactattgg tgccacttta tatgacgcac cattagcaca
    46021 gtccaaaact acttttaatc ccttaaagtc agtgcttatt attgatttta ggtagtctac
    46081 atagtctctt tgtgcacaat gttcatgtaa ttttcttcct acattttcac caattggaag
    46141 acaatcaatt ttgtctatat cgtctatata ttcttctatt ttcaattcaa tttcatcatc
    46201 taatttatat ccattcttat taaagaattt gattccatta tattcaacag gattgtgaga
    46261 tgcagatata accacaccac aatcagcacc atattttcta gttaaatatg ccactgcagg
    46321 tgttggtatt attccaacag taataacatc acatccaaca gacataagtc ctgctattaa
    46381 agatgcttcc aacatatcac ctgatattct agtatcctta cctactacta cttttactct
    46441 gtggtctcct tgagctaaga caaatccacc agctctacca agtttatatg ctaaatcaca
    46501 tgttagttct gtatttgcta ctcctctaac tccatctgtt ccaaaatact ttctcactaa
    46561 agattctcct ttcataattg aaaagcttgt aatttgtatt atatttttat agttcataaa
    46621 atatcattat aggcttaatt tcagtcataa aaatatttta atacttatca gcaaaaaaga
    46681 caatagaaat aattctattg tctttttttt gacatctttt tctttattag ttagttgctt
    46741 tagaacatgt agcatccata cctttttgta aagcttctct gtttaatgga acgaattttt
    46801 cttttctagg tccgaaaact tttttgaatg cttctagtac agattctata tctacagtat
    46861 cagatacttt taagtaagcg cctaacatta tcatgttagc aactttatca tttcctaatt
    46921 cagctgctaa ttcatttgct ggtatataat aaacatctac atctgttcta tcaacttttt
    46981 cttttattaa agaactattt actattattt ttccaccagg aataacatca tctttgaatt
    47041 tttcaaatgc tggtatattt aataatatag ctgcagttgc atcatctgtt ataagtggag
    47101 aaccaactgg ctcattagat acagttactg cacagtttgc tgtacctcca cgcatttctg
    47161 gtccataaga tggtaaccaa gaaacttctt ttccttctag cattcctgca taagtaagta
    47221 attgtcccat agacataaca ccttggcctc cgaagcctgc acatattact ctagctgtag
    47281 acatttactt cacctcctca acttcaacat ttttgaaatt tcctaatgga tagtatggta
    47341 tcatgttgtc tcttaaccat tgtaaagcat cgtttggagc tagtccccag tttgtaggac
    47401 aagtagataa tacttctact attccaaatc ctaatcctgc ttgttgaact tggaatgctt
    47461 tctttatagc ttttttagct tgtctaacat gagctggagt atcaactgct actctttcta
    47521 caaatacagc tcctgttaat gtagctaaca tttcacttac tcttattgga taaccttgag
    47581 tttcagcatt tcttcctgat tgagcagtag tagctctttg tccaactaat gtagttggag
    47641 ccatttgtcc accagtcata ccataagttg tattgtttac aaatatagta gttatttttt
    47701 ctcctctagc agctgcatga actatttcag cagtaccaat tgaagctaag tctccatcac
    47761 cttgataagt gaatactgta ttttcaggat gaactctttt tattcctgta gcagcagctg
    47821 gcgctctacc atgagcagct tcttgagtgt cacagttaaa atatttatat cctaaaactg
    47881 aacatccaac tggaacaaca cctacagcat cacctaatac tcctagttct tctaatactt
    47941 caccaactaa tctatggatt ataccatgtg tacatcctgg acagtagtga gtttgagtat
    48001 cttgtaatcc ttcagttttc ttaaatacaa cagccattat ctagcacctc ctgcaaccaa
    48061 ttctccggca ataatttttt tagctttttc aactatttct gctggtgttg gagtcattcc
    48121 tcctggtctt ccatggaagt aaactggtaa tttaccttct actgccattt taacatcttc
    48181 caccatttgt cccatactca tttcaacagt caatatgttt ctagcattag gaatttggtt
    48241 gaatgcttcg aatgggaatg gccataatac tttaggtctt ataagacctg cttttattcc
    48301 ttcttctctt aatatatcaa ttgcgctttt tactactctt gaagtagttc cataagctgc
    48361 aaatacaaat tcagcatctt ctgttttgta catttcgtat tgtacttcat tcttttccat
    48421 tgcatcaaat ttttcttgta aatgccaaca atggtcttct agtacttctg gctctaagta
    48481 tagagagttt attacattag gttttctttt tcctttagtt ccaacagttg cccaatcttt
    48541 aggaggcaat tctcttttct tctcaggagc tctaaattca actggctcca tcatttgacc
    48601 tatcatacca tctgcaacta ccataactgg tgatctgtaa taatctgcaa cgtcaaaagc
    48661 ttccattatc atatcaacag cttcttgaac tgtagctggt gcgaatactg gagttctgta
    48721 gtctccattt cctccacctc ttgtagacat aaagtagtca gcttgtgaag gttgtatact
    48781 tccaagtcct ggaccacctc tcattacatt aagtacaaca caaggaactt ctgctcctac
    48841 tgcatatgtt ataccttctt gctttaaagc aactcctggt gaagatgaag aagtcataac
    48901 tcttgctcct gcacctgctc caccataaac catgtttatc gcagaaactt ctgattcagc
    48961 ttgaacgaac gctccaccta ttttaggtaa ctctcttgat aaatattctg gtaattcact
    49021 ttgtggagtt attgggtaac cgaagaaata tttgcaacca gcttctatag ctgcttttcc
    49081 aaatgcttcg ttacctttca taagtatctt agccattaaa attccccctt aaatattaat
    49141 taaattaatc tctttctact gttataacta catctggaca catagttgca caacttgcac
    49201 atcctatgca tttttccatt tcaaaaacag ttgctgggtt ataccctttt ttgtttatta
    49261 catttgagtc taattgtatg atttttactg gacatgcttc aacacacaat ccacaacctt
    49321 tacaacgttc ttgattaaaa gatacttttc ctttagccat ttacctaagc ctccttaaac
    49381 tttctatata tttgagctca aactacatcc agtcttctct catatataat tttataggaa
    49441 aaatttctcc ttctaaatct tttggtaact gttcaacaag attttctaaa catgcaacat
    49501 atcttatcgg tatattacat ttttcagaaa cttcttttgc aactttctga cctcttaaaa
    49561 catcatcaat agtagtaaac ctaataagat gagtattatt aattagacct gttaccttta
    49621 atttagaaga tttttctatt tcttttatat attggataac ttcttcagaa gtttgagttt
    49681 tctccctatt tgcatttatt acaaaaagca tatcataatc gccttctttt aacaaatgac
    49741 taaatcttcc tataacccta gcacctacat tatctccacc taaatctata acagaattgt
    49801 atgaatggtc taccatagga gacattacct ctgctgatac tgctggtaaa tctaatgttg
    49861 gagcattaat tgagctatct attggttgta tacctaagga tttcattaac tctttctttt
    49921 ctctagttct aaagtataca tttaccacat ctaaatcggc tatagcaact ttgccagaaa
    49981 ccatatctct taacttaaca acatagttca tcgcaaattc acttttacca cttccatagt
    50041 gaccagttat gattcttatt cttttatcat tagttatcat aaacttgagc ctcttcttca
    50101 ccagttaaaa ctctaagtcc accttgagct aatgcaatca tttcatcttc acctggataa
    50161 acttttacat ctgctataaa tttaactcta tctgcaatca tttctgtaaa catttttgaa
    50221 tatgcgattc caccagttaa taatattgct tttacatctc ccttaagaac tgcagcacta
    50281 gctcctattt ctttagagat ttgatatgcc atagcttcat atgctaattt agctttttca
    50341 tcaccagctt caattctttc ttcaacttct ctagcatcat tagtgtttaa gtatgcaact
    50401 aatccgccat taccttttat tttcttttta atttcatctt gagtatattt tccactaaag
    50461 cacattttta ctaatgcacc tactggtagt ccaccacttc tttctggaga gaaaggtcct
    50521 tctccatcta atgcgtttgc aacatctact attttaccat ttttatgagc tccaacagaa
    50581 actcctccac ccatatgtgc aactataaga tttatatctt catatttctt gtttatttct
    50641 ctagcatatc ttcttgctat tgccttttga tttaaagcat gtactacact tgctctactt
    50701 atttcaggca taccagaaat tctagcaaca tcttctaatt catctacaac aacagggtct
    50761 actatgtatg aaggaacatt tacttcttca cctatttgtt ttgctattat tccacctagg
    50821 tttgaagcgt gttctcctaa aactcccact tttaaatctt caatcatagc agcacttact
    50881 gaataagtac caccttttat aggtttaaga agtcctcctc tacctactac agcatctaat
    50941 tcagatgttt ttactccacc ttcttttaga gcttcttcta ttacttgttt acgaaattca
    51001 aattggtcag acaccttctc atattttcct atttcttctg aagaatgtct taaagttttt
    51061 tcaaatacta aatcctcatt atcaaataca gctattttag ttgatgtcga accaggattt
    51121 attgttaaga ttttaaatat tttgctcatt tgcctatttc ccccttaaaa ttatgccttt
    51181 gctgccatta aaacacctaa agctattgag tttagtttag tttcttcact gtctgctcta
    51241 gaagttaata ttattggtgc tttagcccca actataactc ctgcattttt tgattttgag
    51301 aagaatacca aagctttata taatatgtta ccaccttcaa tatctggggc taataatata
    51361 tcagctcttc ctgctacagg atgatttata cctttatgtt tagctgcttc taaagatact
    51421 gcattatcaa ttgcaaaagg tccaccaacc atacaacctt tgatttctcc tctttcatac
    51481 atttcttcta gttctttagc ttcaactgta tctttcattt ttggatttac tttttctttt
    51541 gcgcatattg cagcaacttt tggttcactt atatctaatg aatgtgctac tgtgcaagca
    51601 ttttctatga tttgcttttt agtatttgta tcaggagcta agttcatagc tgcgtcagtt
    51661 acgaaaaata atctatcata tccctctaca tcaaatactg ctacgtgact taatacattt
    51721 ccagttctaa gacctacttc tttatttaaa actgctttta gtattattga tgtgtctact
    51781 aagcctttca ttaccatgtc ggcttttcct tgtgaaacta attcaacaga ttttagagat
    51841 gcttctgcta aatcttttat atctatcagt tcataatttt cgatatccat gtctatgctt
    51901 tttgcaattt ctttagtctt ttctatatct cctactaaaa tggcatttgc tattttttct
    51961 tttctagcca tttcaactgc cattaaaact tctttatctt ggcaacatgc tactgatata
    52021 gttttaggtc ctctttcttt tgcaaactta attacttctt caaaacttct catgcatttc
    52081 cacctcatct tgaatttttt gaaatagaac tttttatatc tcaattaaat tataactcgt
    52141 tcagcaacgt tttcctagag ataattgaaa tatttaattc aaaatattta tttaaatcta
    52201 tttatcagtc ttttttcata tatctagcgc tttttagatt taacaaatat ctcattgtcc
    52261 ttattttata atataactaa aataaacaag atgcaacaaa aacataaaat taacaaactt
    52321 aattttatag gtttttttgt cgcatcttgt aacaactaaa tattcgaaat atttgttcat
    52381 tccacttcaa caatattagg ttctatattt atttttttaa attgatatgt tgtttcatat
    52441 tttattttat atttactatc ttcctcagga ccttgtgata aatcaatata taatgaaata
    52501 tcttttttat ttaacttact caaatcctcc attgactcta caacaacttt tatatctaca
    52561 tcagaaatta catttggatt atccatattt gttgggatat ttcttaattc aatatctccc
    52621 gcattatata aaaattctgc actcaattgt tttgtatcat ttaatttaat tgttatagag
    52681 ctatcctcaa gagttatacc ctctggaatt tctaagctaa cttctttttc ttcaccatta
    52741 gccaaatcag ctaagtcaat aggttttgtc ttaatataac ttattttgtc tatatcttct
    52801 ttctttcctt ttattgtaac ttgttcctta cttaatttat agtttttcag tacatcatta
    52861 tctttattat catttagact tactcttatt gggacaattt tttccttcaa tagttctatc
    52921 tttgcagtca caaaggatga acttaatgtt actccttcaa ccttagttcc atcactattt
    52981 aatggtatta attgcaattt tttagaaaaa tcatctgtct cattaccaac atctagatta
    53041 gctcttacac ttttgacttc tttaactaga gttcttggac ctgatacatc gacaaattcc
    53101 ttactaagtt caattttatt tatatttctt tttgaatttc cacttacttc tacctttata
    53161 tctctttttt cttttatgtt tttttcaaga tttactacta aaacatcatg cttaaattct
    53221 agagtaacac cttgaggaat atttgctttt aaatatactt ccttctgtcc ttgtattggg
    53281 tcttcaatgg ttccatatac atgtatatct tcttttttaa cactttgtac ctttgataaa
    53341 ctacctttta tatatacatc tgctgttaat ttttcgtctg gatatataac aagattttta
    53401 tcctttaaat cactcatatt acttatagat acaggtatat cttcaaaccc tttagtttct
    53461 tcagggtcaa ctacagccat aacatacatc cataatgcaa ttgcacttaa aaatgatatt
    53521 atttttattt tggtattatt ttttagtcta tttatcattt aaatatacca cctttgaaaa
    53581 aacttcttgt ttctgtattt gtttttaaat tactacgtaa tatattcatc attctttctc
    53641 tagaaatatc tctatataac ttacctgctt tagcaattga tacgccacct gtttcctctg
    53701 atacaatcaa agttatacag tcagacacct cacttacccc tattcctgct ctatgtctag
    53761 tacccaaatc tttacttaaa tccttacttt ctgtcaatgg caaaaaacat gcagctgctt
    53821 ttaccttaga atctctaatt acaacagctc catcgtgtaa tggtgtattt ggtataaata
    53881 tatttattaa tagttgccta gaaatttcag catcaataat agttcctgta tttattatat
    53941 cacttattct agtttctctc tccattatga taagagctcc tattttttgt ctagaaagtg
    54001 aatataaagc ttctacaatt tcttctatat ttctattgag agtttcttca gaagtattta
    54061 cattctttcc aaataaatta aactttgctc ttcctatatg ttcaagtcct gctctaaatt
    54121 ctggttgaaa aattataaga gcagctataa ctccataatc taaagcttta agagatatcc
    54181 aataaacggt atgcaattta aaggtgttac taagttgagt tgctaataaa agaaatatta
    54241 tacctttaaa cacttgttct gctcttgtat cttttataaa cataaatatt ttgtaaaaaa
    54301 tatacgctac tatagatatg tcaattaaat catatatact cattcttaat attatattaa
    54361 aaaatccatt taaaaaagaa tttatatcta acacagtttt atcctcctgt ttgataactt
    54421 cttaattatt tacactaagt attatactat ataaatctaa ctctatacaa actatttaac
    54481 ttttatgtaa ataattctag ttttatattt ggagattgtt aaataatctc taaacacatt
    54541 aaaaatatca acttaataaa tacatatttc ttattaaagt tagtttttac tcaaataact
    54601 caaaccatca aggcgcgaat acaaaatagt actcgcgcct taattcagtt ttatgttcta
    54661 aaatatctta atatatcttt gtttaatata tattaattat tataaattct ataatccact
    54721 tattaactat aaacaaatac aaaatctaaa tattacttat catcaatatt attccattag
    54781 attcattttt atattaaagt aataacttat ttcatatcta gattagataa atttatttta
    54841 atatcttact ataaactatc attaaaactt attatgtata actagatata atctcctaca
    54901 gtgaaaataa tacacaatac ctaaagttat atatccattt cacagtataa taatttattt
    54961 agtataactt ataaatatta cattaaattg taaattcact atagtctcta attttttata
    55021 atttcttata cttattgttt agacaaaaat atgctcatga atctctttat aaataatttc
    55081 ataagttatt tcaatatata aataccataa agtatacaat ataatgtata taactcttac
    55141 taattagtta tatttattat atttaactga tgccttcata aacatcttgt agactattat
    55201 acattaccct ccgtatgttt acaatattaa tgaatatact gtaactctat tagaatatac
    55261 tgtaattttt acatagttta aagtttataa ataaaaagac acaggtaata tacatgtttc
    55321 ctgtgtcttt ttaaacaata taaaagttta ctataattta tagtaaactt ttcttaatga
    55381 gcgcacaggg attcgaaccc cggacacacg ccttagaagg gcgttgctct atccagctga
    55441 gctatgcacc caagttatta tggagcggga aacgagattc gaactcgcga cttcaacctt
    55501 ggcaaggttg cgctctacca ctgaactatt cccgcttatt taatttggcg acctggaagg
    55561 ggctcgaacc ctcgacctcc agcgtgacag gctggcattc taaccaactg aactaccagg
    55621 ccgcgaatgg tgggaccaac agggctcgaa cctgtgaccc cctgcttgta aggcaggtgc
    55681 tctcccagct gagctatggt cccatttttg gagcgggtga aggggatcga accctcacag
    55741 ctggcttgga aggccagaac tctaccattg agctacaccc gcatatttaa ttgaattggt
    55801 gactcgtagg ggaattgaac ccctgttacc gccgtgaaag ggcggtgtct taacctcttg
    55861 accaacgagc cgttttaatg gttgcggagg caggacttga acctacgacc ttcgggttat
    55921 gagcccgacg agctgccaac tgctccaccc cgcgatattg ttttataagt gccgaagacc
    55981 ggaatcgaac cggtacgaga ggtaagtccc gcaggatttt aagtcctgtg cgtctgccag
    56041 ttccgccact tcggcttttt tggctccaag ggtggggctc gaacccacag cctaccggtt
    56101 aacagccggt tgctccaccg ttgagctacc ttggaacatt t
//
LOCUS       DAMJWC010000020        52622 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMJWC010000020 DAMJWC010000000
VERSION     DAMJWC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.020"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(206..817)
                     /locus_tag="PC503_001407"
     CDS             complement(206..817)
                     /locus_tag="PC503_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2527403.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(909..1898)
                     /locus_tag="PC503_001408"
     CDS             complement(909..1898)
                     /locus_tag="PC503_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF2527404.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1965..2828)
                     /locus_tag="PC503_001409"
     CDS             complement(1965..2828)
                     /locus_tag="PC503_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF2527405.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2934..3530)
                     /locus_tag="PC503_001410"
     CDS             complement(2934..3530)
                     /locus_tag="PC503_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF2527406.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3570..4373)
                     /locus_tag="PC503_001411"
     CDS             complement(3570..4373)
                     /locus_tag="PC503_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF2527407.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDRTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4409..4849)
                     /locus_tag="PC503_001412"
     CDS             complement(4409..4849)
                     /locus_tag="PC503_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF2527408.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4862..6964)
                     /locus_tag="PC503_001413"
     CDS             complement(4862..6964)
                     /locus_tag="PC503_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF2527409.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7225..8928)
                     /locus_tag="PC503_001414"
     CDS             complement(7225..8928)
                     /locus_tag="PC503_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF2527410.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8954..9913)
                     /locus_tag="PC503_001415"
     CDS             complement(8954..9913)
                     /locus_tag="PC503_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2527411.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(10049..10567)
                     /locus_tag="PC503_001416"
     CDS             complement(10049..10567)
                     /locus_tag="PC503_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF2527412.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10610..11095)
                     /locus_tag="PC503_001417"
     CDS             complement(10610..11095)
                     /locus_tag="PC503_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF2527413.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(11092..11709)
                     /locus_tag="PC503_001418"
     CDS             complement(11092..11709)
                     /locus_tag="PC503_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF2527414.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11774..12136)
                     /locus_tag="PC503_001419"
     CDS             complement(11774..12136)
                     /locus_tag="PC503_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2527415.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(12880..13377)
                     /locus_tag="PC503_001420"
     CDS             complement(12880..13377)
                     /locus_tag="PC503_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2527416.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13552..14463)
                     /locus_tag="PC503_001421"
     CDS             complement(13552..14463)
                     /locus_tag="PC503_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2527417.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15387..16238
                     /locus_tag="PC503_001422"
     CDS             15387..16238
                     /locus_tag="PC503_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2527418.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16242..16712
                     /locus_tag="PC503_001423"
     CDS             16242..16712
                     /locus_tag="PC503_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527419.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16725..18035
                     /locus_tag="PC503_001424"
     CDS             16725..18035
                     /locus_tag="PC503_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2527420.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18247..18993
                     /locus_tag="PC503_001425"
     CDS             18247..18993
                     /locus_tag="PC503_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527421.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19355..20896
                     /locus_tag="PC503_001426"
     CDS             19355..20896
                     /locus_tag="PC503_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2527422.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20931..22037
                     /locus_tag="PC503_001427"
     CDS             20931..22037
                     /locus_tag="PC503_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2527423.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFQGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGEIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22416..23702)
                     /locus_tag="PC503_001428"
     CDS             complement(22416..23702)
                     /locus_tag="PC503_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2527424.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23825..26923)
                     /locus_tag="PC503_001429"
     CDS             complement(23825..26923)
                     /locus_tag="PC503_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2527425.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVTLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27649..27807
                     /locus_tag="PC503_001430"
     CDS             27649..27807
                     /locus_tag="PC503_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527426.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(28094..28798)
                     /locus_tag="PC503_001431"
     CDS             complement(28094..28798)
                     /locus_tag="PC503_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527427.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28789..30396)
                     /locus_tag="PC503_001432"
     CDS             complement(28789..30396)
                     /locus_tag="PC503_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF2527428.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30650..31828)
                     /locus_tag="PC503_001433"
     CDS             complement(30650..31828)
                     /locus_tag="PC503_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527429.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(32054..32548)
                     /locus_tag="PC503_001434"
     CDS             complement(32054..32548)
                     /locus_tag="PC503_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2527430.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNIGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32549..33310)
                     /locus_tag="PC503_001435"
     CDS             complement(32549..33310)
                     /locus_tag="PC503_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2527431.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            34012..36846
                     /locus_tag="PC503_001436"
     CDS             34012..36846
                     /locus_tag="PC503_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527432.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIMHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36889..38133
                     /locus_tag="PC503_001437"
     CDS             36889..38133
                     /locus_tag="PC503_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2527433.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(38548..40290)
                     /locus_tag="PC503_001438"
     CDS             complement(38548..40290)
                     /locus_tag="PC503_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527434.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(40274..40948)
                     /locus_tag="PC503_001439"
     CDS             complement(40274..40948)
                     /locus_tag="PC503_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527435.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(40985..41974)
                     /locus_tag="PC503_001440"
     CDS             complement(40985..41974)
                     /locus_tag="PC503_001440"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2527436.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(42022..43266)
                     /locus_tag="PC503_001441"
     CDS             complement(42022..43266)
                     /locus_tag="PC503_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2527437.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(43308..45854)
                     /locus_tag="PC503_001442"
     CDS             complement(43308..45854)
                     /locus_tag="PC503_001442"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527438.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(46062..46223)
                     /locus_tag="PC503_001443"
     CDS             complement(46062..46223)
                     /locus_tag="PC503_001443"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527439.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(46279..47295)
                     /locus_tag="PC503_001444"
     CDS             complement(46279..47295)
                     /locus_tag="PC503_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2527440.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(47292..48590)
                     /locus_tag="PC503_001445"
     CDS             complement(47292..48590)
                     /locus_tag="PC503_001445"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2527441.1"
                     /translation="MIDSEEMIFNVEDLIIYRKNQLVIIYNKKFRKYIKLSEEIYKYF
                     LLGQENKIKIYDFVNYFDDESDKKYIINLIDIMNKNQIFKSNNLNFDMLSNGVAIYFC
                     LTNRCNLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFF
                     EIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKG
                     VFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGR
                     GLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDV
                     YPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIF
                     CWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            complement(49056..50375)
                     /locus_tag="PC503_001446"
     CDS             complement(49056..50375)
                     /locus_tag="PC503_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2527442.1"
                     /translation="MLNINVFWIFLPIFSTAIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
     gene            complement(50369..50497)
                     /locus_tag="PC503_001447"
     CDS             complement(50369..50497)
                     /locus_tag="PC503_001447"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527443.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(50636..51346)
                     /locus_tag="PC503_001448"
     CDS             complement(50636..51346)
                     /locus_tag="PC503_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527444.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKKTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
     gene            complement(52437..>52622)
                     /locus_tag="PC503_001449"
     CDS             complement(52437..>52622)
                     /locus_tag="PC503_001449"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527445.1"
                     /translation="KDGTIVPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPARTTT
                     VSSLLGRIAVNIFNFNK"
BASE COUNT        17806 a         8608 c         5603 g        20605 t
ORIGIN      
        1 ataaaaaaat tacctaatac agtaaattaa ttggtaagat aaattattta ttattagtaa
       61 agtaaattat ttactattta tcaagataaa ttatttataa aataaatcat ttataaaata
      121 taatttatac tttgaaaata aaataaacta tcttccaaac attttattat atgcttaaaa
      181 gatagttttg tgtctttaaa ataaattaaa ttgtatatat tccttcacat aacttttgta
      241 tattactagg tggttgccat ttaccatctt ttttagtata tgtaatcata gttgtaactt
      301 ccttagttgg tttcttattg taaaggtcta taatcatttt tgtcatatca tcttgaactt
      361 ctttttcttt tttatcgtaa ttcttttcat cagttacata agattttact aaagtgttcg
      421 cttcactcat tactttacta gtatctaaag ctttacttac aactttcaaa gttatcttat
      481 ccttactaga agattccact gttactgtct tttcaacacc ttgaattaat ttaacaattg
      541 tttcgtatat cttttcagca ttttctttac cataaagagg tgtcaattga gcaatcattg
      601 aaaccttgtc cttgctgtta taagtttgaa tctgtttata ttcagcttct gttaatgcat
      661 cagaaattcc tttttcatca tacttataca tttctaatgc agctaaatta gcttcaaaat
      721 tcgactttac tttttcttct gcattagaac accctatagt tagaactaaa actagagcca
      781 taatcgtaga taatattaac ttttttacca ttttcataca aacatcctcc ctcaattaaa
      841 ataataaaaa atttatttat caacattata acataaattt gtctaactat agaattattt
      901 tgaatatttt accacttcca gtctattcca ataccgtttt cttttgcttt atcgtatatt
      961 ctttttgctg ttacgacatc ttgtacacct atcccaacag ttttaaatac aattatctca
     1021 tcatcatctt ctcttccagg aatagttccg tttataacat ttcctaaatc accactaaaa
     1081 tcatctttac ttatcttacc ttcttttaat ggaattaata tatctcctga ctcagataaa
     1141 actgcatctg ttgattcaaa aaatatctta gacgctctag ttaaacagtt tgggcacaac
     1201 tcttgcatat ctggcatata tgaacctact gcacttatta aagctccttt tttcactaag
     1261 tttccattaa gtactggttg ttttgatgga gtagctaaaa ctatcacatc tgcgttatct
     1321 atggcttcgt cagatgattc aactgcaact attttagtat tatatttact taattttaag
     1381 ttcatttctt ctgcaaattt ttctctactt tccttgtttc tactaaaaac tcttacctca
     1441 tccaaatttc tagcttctat catggcttca agttgtggct caccttgtcc tcctagacct
     1501 atcaaagctc caatcttaga atctttttta gccaatacgt ctatagctgc tccagaggct
     1561 gctccagtac gaatctgagt tacataagta ccatccaata ctgcactaac ttctccagtt
     1621 tctccatcta ataatagtac tgttgctgga attactggtt tgcctttttg agcattttta
     1681 ggaaatacag atacaatttt tattccccca cagcctaatt cttctacgta tcctggcata
     1741 aataacatac tagcatcttg acttggaaca gatatattgg ttctcaaagg atttacactc
     1801 tttccttcac aataaattct aaaagcttcc ttatcagctt caattgcatc tctcattgta
     1861 aatacttttt ttatgtcgtc tttttttaaa agtagcattt ttataccccc aattttaata
     1921 agtctctatg ctaaatatta tagcataaca tttaatttaa tcttctattt caaatcaaat
     1981 aaatctacat actctggttt tagcatagaa cttatcaacg ctttatttat tgaaaattct
     2041 ggtattcctg ctgcatatgg agttatatca tacaaatcaa aatatacaac tagattctca
     2101 tcttgcaagt aaaagttttg attctctttt atacctttaa aattatatat tccgatattt
     2161 tcttcatcct ttttttcaag ttcagctatt tgtcttttaa tttcttcatc tataacttct
     2221 ttatatttag tattatcctt aaacaagtcc attaattcta aaaattttcc agttctcata
     2281 tccacattat atgctatatc ttgataaaat ccatgtgctc caccactata agtataatat
     2341 ctcactttta tactaagagc agaatcagta ttctttttaa gttcaaagtc tacatttgca
     2401 acaaacttat ttttctcgtc aggattatcc ttaagatact gctttgcttc tttatatgat
     2461 ttattataaa attcaaatat gtcatttttt atcttatcat ttgtagacct ttcaacaatt
     2521 ttatttgaat ttgttattac aggcatgttt atagtacttt ctaaatactc atcatttttc
     2581 actattgttt tacttcctat tgtacttact gataaagttt gtttactatt tgtattaccc
     2641 tttggtaatg actggttact cataacagtc actgcttcct tattactatt taaattaatt
     2701 gaagcatctt tccttaaatt attatattta tagtcatgtt taattgccaa aacagccatt
     2761 atagtcaatg ttaaaacaaa tacatatctt aaaactttag cttttgtatc gactttaaaa
     2821 aatttcatat tatcattttc ctcctaaata taaatctctc ttattatatt tggagtttct
     2881 agggtttttt atccatataa tttaataaaa gattaatttt tatttataaa aaattaatct
     2941 ttttgtttta aaatattaat atgtcttatc aaacagtttg aaatttcacc aagaggtaat
     3001 tgtaacataa cagaacctct atcaaaagct accattggca ttccatatac tatacaagaa
     3061 ttttcatcct gtccaattgt aaatgaacca ttttctttca tttttaaaag tccacttgct
     3121 ccatcataac ccatacctgt aagtattatt cctattgaat ttttacctgc tacttctgct
     3181 actgaatcaa acaaaacgtc tactgatgga cagtgaccac ttattctttc tcctttttca
     3241 caagttacat aatatccttg tttatccgta cacaatttca tctggtaacc cccaggtgca
     3301 attaacacat ttccttgttc tactctatca ttattcttag cttctcttac attcataata
     3361 cactgcttgt caagccgttg tgcatacata taagtaaata tagctggcat atgttgaact
     3421 acaacaatcc ctggtgttga ttttggtagg tcttttataa tttcaagtat tgcctctgta
     3481 ccacctacag atgcgcctat agcaataacc atattattaa aacgttccac attaccgcct
     3541 ccaaaaaatc atatatcaaa aatacctttt tatcgtttat atatagcagg ttttacatat
     3601 ttgtatttag tactacttct gttgattact tctgcatgtc ctacaaacaa aaaactatct
     3661 tttttggtag cattataaaa tttatttata agttcttctc ttgtttttaa atcaaaataa
     3721 atcataacat ttctacaaaa aatcaaatca aaatgttgat atgagaaatc attcattaaa
     3781 ttaaacggct taaaaattac actttttcta atcttatcac aaattttaaa tgtaccatcc
     3841 ttgttgtcta taaaatactt cttcttccat aactcaggaa cattgttaac atttgattct
     3901 atgtatatac ctcttttagc tttttcaagt gagttagttg aaatatctgt ggctatgatt
     3961 ttaatgttcc acaactcttt attatatcca aaataatcat ccaaagtcat agctattgaa
     4021 tacgcttctt ctccactaga acatcctgca ctccatatat ttatgtttct tattttatta
     4081 ttttcttccc aaaaaggaag tatactattc tgtataaact caaaatgttg aggttctctc
     4141 ataaaaaatg tgtggttagt actcaatcta tttattaggt ttatagcttc atttcctgtc
     4201 ctatctttaa ataatagatt catatattga ctaaaagaac taagtttttt ctctatcatt
     4261 gtattgtata agcgaccttc aattaacgct ctttttttac ttaaatcaat accatattct
     4321 ttttttacat ggtttacaag aactataaat tcttcatctg tgagttttat catgcaaaaa
     4381 cttcctcctg ctaatttatc agaactaact atatgctatt aatcaaaaac tttcgaatat
     4441 ctaaaattaa tatagaatta tcttcaactt tcgcaatctc ttttatatct ttattaatat
     4501 tagtgttgtt agaattagtc gtctctagta aatttagatt ttctatatga ataacatcaa
     4561 caactttatc tacaataatt ccaacttgat actcatcaac ctttgtaatt attatacaag
     4621 ttctctcatt ataatcagct ttaggaagat tgtactttat atgcatatta ataactggta
     4681 ttattcttcc tctcaaatta ataactccac ttatatatgt tggaagacat ggtacatacg
     4741 ttattgattg aaatcttatg gtttcaatca cattttctaa ttctattcca taaataacat
     4801 cattgacata aaatgttaat acttgtttaa taatttcatc tttagccata ctttaaatcc
     4861 cctaatatat ttctataatg ctatctgcat ctataattaa acttatactt ccatccccaa
     4921 gtattgtaca tcccgataaa cccttatttt ttatattaaa tcggttaaaa taaactggaa
     4981 atggtttcac aacaacttgc tgattaccta ttatttcatc aacaaaaatg catactgctt
     5041 tatgctcatt ttcaataatt atcatattac cattcatcag attggttact tttgtttgaa
     5101 tattatatat tttatgtaac cttataatgg gaatacatgc tccatatatt gtaattaact
     5161 ctgtcttatt tccttctgta attatttgat ttaagtctgt aagtttaaat gttcttctta
     5221 tggatgatat tggtaaagta aatagtgaat ctccaacttt aaacttcata ccctctacta
     5281 tagaaagagt taatggtatt tttatagtaa aggttgtccc ctcatcctgt ttacttttta
     5341 cttcaattga acctccaact ttttcaatac ttttacgaac aatgtccatg cctactcctc
     5401 ttccagaaaa ttcagttata gattcttttg tagaaaagcc tggagtcata atcaaagaat
     5461 tgacctcgtc atcagtatac tcattacttt gatgtttaag aagaccttgt tccttagctt
     5521 ttgccaaaat cttatctctc ataatgcctc taccatcatc tgaaatactt atcacagctt
     5581 ctccgcctag attttcagca gataaaacta tctttcccac ttcttcttta cctttcgcta
     5641 tacgctcctc aataggctct attgcatggt ccatagcatt tcttataagg tgcataaaag
     5701 gttccgctaa attatcaatt acactcttat ccacctctgt ttctgctcct atagttatta
     5761 actctacatt tttatctaat tttttattca tatctcgtac aattctatgc attttttgaa
     5821 atacaccagc aatttgaatc atacgcatag acattactat atcttgcaat tcatctgtaa
     5881 gcttgtgtaa ttgtcttgtt gccttattga aattatctat atcaacacct gtagaattta
     5941 cgctatttac aaccattgat tccataatta caatttctcc aactatattt tgaagtaagt
     6001 ccaatttttc taaatttaca ctcataatac tctgcttact tattggtaaa tgttcatttt
     6061 cttcacttag actatctttt tccatatcag ttttttcatt taaaacatct tcttgtatct
     6121 catcttctgt atagttattt tgataacttt tacttacttt attattatct tttaatttat
     6181 tttctactgc atcattgttt gatgtacttt tcatttctat ttctttttta ctaatattta
     6241 tgtattcttt tacatagaga ttatcttcta tagttttata aactattgcc ttatcctctt
     6301 tagctacaaa ttgtatataa aacccataac ttttaatata ctctgtagac tctgcatttg
     6361 tttctacatc ttttggataa aaatctataa attcacagta atctctaagt tcaaatacaa
     6421 gcatgaaagc tctcacattt tccatcatgc aaccttgttc aaagattatt tttactacat
     6481 cagagtcttc tttgtattca aaatttgaat cgattacttc tttttcgtct ttactttcta
     6541 aatttgcatt atcctttgat ttcatagaac ttgataattc caaagtactc acatactctt
     6601 caattccttc aataaaatta gagtaatcag aagatataca acctcttgat tgtaactcat
     6661 ctatatctct tcttataaaa tctaatgatt gaaagactaa atcaaataat aggtcattgt
     6721 ctaaaacttc tattttacct tcacgtatag cataaaacaa gtcttctaca ctatgtgcta
     6781 aagcagatat attgtctaac cccatcatag atgctgaacc ttttatcgta tgcattattc
     6841 taaaagtttc attaatgttg ttatgagtaa atactttctc tttttctatt tgaatcataa
     6901 tttcatctaa ttgttcgagt aataaacttg tctcaaatat aaacatatct aacatttgtc
     6961 tcatactcgg ttcaatataa ttcacattta tcacctacga cctacaaata attttctatt
     7021 atatatgcat ctcataattt aaatccttga tgattctctt atctcactat atgtacctca
     7081 taatttaaat acacaattat tctcttactt caatatatat acatctcata atttaaatcc
     7141 ttgataattc tcttatttca atatatatac atctcataat ttaaatacat gataattctc
     7201 ttacttcaat attcacctca taatttaaac ccatgatgat tctcttactt cactttcctt
     7261 tagatgaaat ttttctacta attcttttaa aatttgagcc tgagcagaca tctcttctga
     7321 ggctgctgca ctttcctctg ctgttgctga gttcatttgg actactatgg aaatttgctc
     7381 tattccagat aaaatctgtg taattgctac ttcttgacta tgtacagccg aagaaatacc
     7441 attaatataa ttagtagttt tttctacacc atttactacc aagtccaatg catttgcagt
     7501 ctctttagca attctgacac cattttctac tgttttaata gcttcttcta tgagaatagc
     7561 tgtattttga gctgcttttg cacttttacc agccaaagac ctaacttcat ctgctacaac
     7621 tgcaaatcct ctaccatatt gacctgctct tgctgcttca acagctgcat ttaatgcaag
     7681 aatattagtt tggaatgcta tctcatctat tgttttgatt atttttgata tttcactcga
     7741 tttttcactt atttcaccca ttgatgtcat catatcatcc atacatctac ttccaaaacc
     7801 aacttgtgat gcagattggt cagatacctc acatgcaaga ctagcactat ctgcacactt
     7861 cttaattcca tctgatatct cattaatcgt ggaagctaat tcttctactg aactagcttg
     7921 ttcagtagca ccctgtgaaa gagcttgtgc acctgctgca acttgttctg aagcacttgc
     7981 aacttgctct gctgataaat ttatttcaga aaaatcacca ttaaaagagt ttattatact
     8041 ttctaaagat attttaattg atttaaaatc acctataaat tcttggtcta tctctactct
     8101 taaatctcct tttgcaatac tagttaatgt actgtctata aggtctatgt aatttaaaag
     8161 catactttgc atctttttga cagaactcac taatagccct atttcagatt tactttcttc
     8221 aacgtctata cttgttctta agtccccaga tgcaattctt gaaaagtgtt tttctacttt
     8281 attaatagga atcactattt ttaattttat tactgtatat tctattattg tcaatattat
     8341 taaaagggaa agtataaata ttgttcttaa tattagactt tgtaattctt tttttacttc
     8401 tacaattttg gaatttgaac gggtaactat atcctcttga aattcattta ttaaagaatc
     8461 cattttctct tgggagttta tatagtcact accaaaaatt atactttgag ctttactctt
     8521 atcattactt tcgactgcct ttattgcact ttgttctgtt ggtactaaag aatctgatat
     8581 ttcttttgct tctaagattt tatttgactc gctctttgta agaccaattt tttctaattt
     8641 gtttaaagct gattctcttg tttttccgta taattctttt tcataaatat ctttattctt
     8701 tttttctcct gtaaatacat atcttcttaa tacatcactt atctctctag ttgtatcttt
     8761 tatatactga ctttgagtcc tcaaattatt catatcatta atactttttt ctactttttc
     8821 aaatgcttta taagatgaaa tagaagaaaa aatccctgct agaacagcca atactataat
     8881 aatcagcaat acaattgcta atttagaaag ctttacttct cttttcatat ctgtactcct
     8941 tcataaagta agtttatatc ttttttaatc ctttcattgt actcactacg ctacaatctt
     9001 ttcctaagtt tttaccctca tacattgctt tatctgctaa ggatatgttt tcttctaatg
     9061 atatatttga gtttacttct actactccta atgtaatagt gcactttatt ttatgttctt
     9121 tatagttgaa atcaaactcc tttatctctt tacggattct ttctgaaagt atcttagcac
     9181 cttctattgg agtatttgtg agcattatca aaaactcttc tccaccccat cttgatacag
     9241 tatcaatttg tctacaattc ttttttatta tacttgatat tactgttaac acgaaatccc
     9301 ctgcttcatg cccataagta tcattgataa ccttaaagtc atcaatatca ccaaggataa
     9361 gggatattga tgtttcacta tatttattaa ttcttctttg ctccataagc tgattaatta
     9421 tatgtcgcct attgtaaaga cctgtaagat aatctcttac aacgagtcta ttcaattttt
     9481 caagagaaga ttccagttca ttatttatct tttttaattt atcttgagat ttctttactt
     9541 caagatgagc tataacacga gcttttaatt ctgtcatact aaaaggtttc accatatagt
     9601 caattgctcc tacaccaaat ccttttacta tgtctgtatc tgtatttttt gaagttataa
     9661 aaattatagg tatatctgct gtacgagcat tagattttac ttccttacaa aactcaaaac
     9721 cagagttatc tggtaaaatt atatcaagca aaataatgtc tggtataaat tcttcaataa
     9781 attcttttgc ctctattgca ttaaatgctt ttttaacctt aaaattatct tttgtaagtg
     9841 ttttatctat taagtcacac atcagaacac tatcatcaac gactaaaatt gttccctgtt
     9901 gcttattttt catatacaaa cctctcttaa acataatata ttcaaatttt aatgatttaa
     9961 aatttttata cttaataatt ataccactat attcttaaat gttctcatca caatcttttt
    10021 ataataacac tccaactaca tccctatgtt acatgatagt gcaatcaaac ccattgatta
    10081 attcatctat taaaacttca tctttatctg tcaaaagttt ctccaaatct agtaaagtaa
    10141 ttattttacc ttctaattct ccaactccac ttacaaaata atccgaatat tctatagtaa
    10201 ctcttggtgg aggtgatatt ttactttttt ctaagcttac tatatcatca actctatcaa
    10261 ccacaaatcc aactaccaag tcctttattt cagttactac tatatacatg caatttgtag
    10321 tcattaattc atctttttta agtctcaaac gcatatctat tatcggaatg atttttcctc
    10381 ttagatttat tatgccttta gaatatgtag gtagttctgg aataaatata atttcttgat
    10441 ttccagtaat ttctattacc ttttcaagtt caaccccaaa atcttgctca tctactttaa
    10501 actttagata cttaattcct tcatcaatta gtccataatc taaatatggg tcatctggaa
    10561 atctcattta atacctccct cctaaaatac actttctatg aaatatatat tataatttct
    10621 tcttaccttt atttattgaa tctacaagta attcacccgt ctcagtgtaa aaacgtattg
    10681 ttctaccata attcatacct gtgtcctcag ctaatattgg aatatttaat cctaaaagag
    10741 ttttttttac tgcctcaaca ttcctatgtc ctatacttgc aattactgaa ttgctacttc
    10801 ctaaaaacat ctgagcacct ccagcaattt ttgcttttat atatattcta tttgcaccta
    10861 tattctccat agatttaatg agctcattta ttcctgtgtc agcaaattta cacttatttt
    10921 caatgttaat agcatcttta ctatatggca acataacgtg taacattcca ccaattccag
    10981 ctactttatc tatcaaacat actcctacac aagaaccaag tgcataagta actaaaacat
    11041 ttggtctata ggctatcttc atatctgcaa tgttcactac tatctctcta ttcatacttc
    11101 taatcccaac ctcacgagta tttctctaag tgagctcatt tctggaatca tcaaaatgtg
    11161 actagtaaaa taattatcac tcattttaaa tttattttct ataaataaga ctttgtcacc
    11221 aacatctgaa aatcttatca taggtacatt tagaacagct ccaaccatat caatacatat
    11281 atctggaatt gaaacactta tagtcatgtt taacatagat gcaatagcat ttacatatga
    11341 acttgccata atatttccta tttccttaat tgctgaaatt tcaattgcct caatctcatc
    11401 taaaaaagct tcttctttat taaaaagaga acttagcata agttgagtta ttgattcatc
    11461 caacaaaaac ataaacattc cattgatatc acctttcata tcgagtaaaa tacatactac
    11521 tttgttttct ggaccaccaa gcaaatttgt cgcttcatta tattcaagta tcttgaccat
    11581 aggtattaat acttctacat tgctatttat catggatgca agtgcagtaa ttgcattccc
    11641 agagcctata ttaccaattt ctctaagagc atctatatga acatcatcaa gttctaaata
    11701 atttataata taaacccctc cctttattat tgcatttatt tgcttttcat tgtattagtg
    11761 tatatttaca cttttatttt aaagcattat ctacaacttt aactaatgtt tctgttttga
    11821 agggcttcac tataaaatct aacgctccaa gttttatggc ttctacaatc atattctctt
    11881 gtcctattgc agagcacatt acaaccttag cacttgaatc caactttttt atttctctta
    11941 gcacctctaa accatctttt tttggcattg taatatcaag caacatcaaa tcaggctttt
    12001 catatttaaa tatattacac gcttcttctc catcatttgc ttctattaaa ttattatagc
    12061 cacttttact cagagcttct ttaattatca ttctcataaa aatagcatca tctactatca
    12121 aaattttatt ttccataaaa ctaactcctc catatgtaca acaataaacg cttttatctt
    12181 cagttattgt ctatactatc tgactatttt tcgctacaca ataaatacat ttcattgata
    12241 aataaaagta attatttatg ccatattata cttaattctc ttaacataat ttgtcaacaa
    12301 aaaaacttat atatctattg taatatatgt ttggcgtttt gacgagttat taaaaatata
    12361 attgtataaa acataaaaag ttatcaaaag taattaaatt ataataaaac aactttatac
    12421 cttttttatg tttgtataaa aaaaattttc agattcatta aaatcatttc tgtagattca
    12481 tataggattt gactttctca atatctaata gatagttgtt tatttactta attatatttc
    12541 tctatatgta ttatcgatta aattagattt agctttatac attatttttt atatttttca
    12601 aattgtatac tcataaatcc agaagtattc taatgtgttt ataatacttt ttttcatatt
    12661 ttaaattaaa taacaaatca ttatatttac aagtatcatt tatcaataaa caatattaaa
    12721 tgaagaatat gtctgaagat tcaaagtgat actgatacta ttaattacta aaaaagcagt
    12781 aaatctttta cagatttact gcttatagtt ataaataata aaactatcta taataaatgt
    12841 actatactca atatttcatt caatatagta ataacaaatc tactttattc ctatgtaaat
    12901 atgaatttct tgtttctttg tatcaaaagt attacattga tactcttcaa aatcacttat
    12961 ataagtccta tcaaaatcca tttgccaaaa ctcaaaccaa aaatctccta cttctttttg
    13021 acctcctact ataacaaact ttgcatactt acctgctggt ataactttac taataatact
    13081 ttctccaaca gtattattag tgtttaattc ttctaaattc ttctctttat cagaattact
    13141 atttacttca caacatgcaa caaagctata cggacttgta aaatcaccct ggtaatctgt
    13201 atatagacct attgtcttgt cattcttttt accctttata gcattatata tccctttgcc
    13261 cataaatttt ttccacaatt cacctatatc atttaccgct tgtccatctt tatttgtagt
    13321 ctccttcgat attcctataa ctattttctc atttatctct actatttcat aattcatact
    13381 ttatacctca ctttgttttt attaatctat tttattttga actaattcaa ttataattta
    13441 taatatacga cacctttatg tcatattttt aatataatta aactcagtga gatattatat
    13501 actaaatgca agatattata tatttaataa aatctttaat ctagcattat attataatga
    13561 ataaatttta gacaactccc ttagtctagt tattacatta tccctaacat ctttaggttc
    13621 aagtacttca acattgtcac caaatgataa aatatatcca taaatccatt caccaatagg
    13681 aaattctgta attacatcat atgtatcatc ttcattttta gttattaaat ccttattaaa
    13741 atcatcaaat actctaaaaa gcatcttttc tttaaacctc aatttcaacg ttatagtatt
    13801 ttccttaatt actttagaat cattcaaaca tacttcttct attatctttc ttgaaaatac
    13861 ttcatccttt atagataaat tccttatcct actaattcta aatatcctaa aatcatcttt
    13921 tagtttacaa aatccataca agtaccaagt cttactctta tacataagct tcagtggttc
    13981 gacagttctg tttgtctggc ttgacaaact atttacataa ttaaaattta tagtattacg
    14041 ccttaaaata gcttctttta tttttgtaaa tttatcatct tcattaaaat tacttcccca
    14101 ttcagtaaag tctatttcaa tccagtttga aaaattctgc tctccaaata ttgagccaat
    14161 tttatttact actgaattta tttctggata cttagtcgcc tgtaatgttt tcagtgcaac
    14221 tattaaactc tctttatctt tttttgacaa tatagccttg tctatagaat attcttctat
    14281 taaagatatc cctcctcctt tgcctttcgt catatatact ggtactcccg acatagacag
    14341 agtttctata tctctatata tggttcttgt agaaacttca aatctatctg ccaactcttt
    14401 agctgttact aattttttat ttaatagaat tactattatt tctgttaatc tatttatttt
    14461 cattcattac cacctactaa aattattaaa tttatttaat ctaaattaat catactaatt
    14521 tttaaataaa taaaatctta gaatcttatc taaattattt ttacatgatt ttatttactt
    14581 tctattatct ttctcacttt ggatattatc atcttaattt atttattact atatcaattt
    14641 acttattatc atctcatttg ttatcgtctt acttaattta cttatttcta tatcaattca
    14701 cttattatta cctcacttgt tatcatctta cttaatttac ttatttctat atcaatttac
    14761 ttattatcat ctcatttgtt atcgtcttac ttaatttact tattgctatg tcaattcatt
    14821 tattattatc tcacttgtta tcgtcttact taatttactt atttctatat caattcactt
    14881 attatcatct taattcattt gcttattatc atttacttta ttcaatttct atatcaaaat
    14941 tagtatttgt acttaatact taaaattaat ttaaagtctt tacatattat ttattttcta
    15001 ttgtaatatt catttccata ctttactaag ctacttccac tcatttattt taaaatttca
    15061 atttactatt tctcaactct atattattat ttttcaattt tatattacta attttaaagc
    15121 tttttagcta ttattcctac aatatttaaa caattttttc ataataaagc tatattacaa
    15181 tatattcaaa atatgtaata ttttagatat ttttcgttga caatgttaaa tttttgtttt
    15241 atccttaatt aaggacatgt tattgacatt tctgaaactt atttgaaata gttttttcat
    15301 tttatttagg aaaacgtatt atacttaaga aaacgtattt tctcatttca gataagtaaa
    15361 atatttattc ttttggggag gaaatcatgg aaattaataa aaaacatttt attcaagtat
    15421 ttttaacttg cttaatcttg gtagtaatat gtgaatttat agggcaaaga actatagcta
    15481 ttggaaaagc ctctatagta ctgttcccta tgctttatgc agttataatt ggacttataa
    15541 taacaccaga tttattaggt aaaaaaatta aagcacttaa aaaagtggtt ggagaaaaag
    15601 aaataaatat tgctggtgaa gttgttggaa ttgcactagt aatgcttggt ataaaatatg
    15661 gtactacagt tggaccaaac attgacaaaa taattcaagc tggaccagcg tttatcgctc
    15721 aagaatttgg tcatatactt gcaccaatcg ttgcattacc tcttgcatta atgtttggaa
    15781 tgaaaagaga agctgttgga gctactgcaa gtataagtcg tgaaccttct ttaggagtta
    15841 tatcagaaaa atatgggata aactcaccag aaggtagtgg tgtacttggt acatatttaa
    15901 tgggaacagt tcttggtact atatacttta gtgtactagg ttcaatatct atttatagtg
    15961 gtcttcaccc atatgctttg ggaatggcct gtggtgttgg tagtggaagt atgatgacag
    16021 cagctgctgg ttcattatct accatggtac cacctgaaat ggcagataca atacttgcct
    16081 atgctgcaac aagcaatatg atgtctagta taacaggaat tatattctta gtttttgtat
    16141 ccttaccatt tactaatttt atgtataaga ttttagaacc taaattttcg agaaataaaa
    16201 aaactaaaga aattaaatct acagaaggag agtgctaata aatgtttgct aatttaaatt
    16261 taaagaaaag ttcatatcaa ttattggtta tgtctgttat tggagttata attcttatag
    16321 gacaaagaat tagcgttggt acatctatag ttacagctct tcctggtatg gtgatgctaa
    16381 tattagctgc tatggcagct atgattataa aagatttatt tcctaaatca atctttccag
    16441 cttttggatt tgcaactata atcggccttt tacttagtat gccatatagt ccaacatctg
    16501 aagtattctt aactaacact aataatatta actttatggc tataactact ccactactag
    16561 cttttgcagg aatttctgtt ggaaacaaaa tagaagcttt aaaagaaatg tcatggaaaa
    16621 tagttataat ttcacttatt gtatttacaa ctatattctt tgcatgtgcg agtatagctc
    16681 atatagtttt aagtattcaa ggtaaaatat aggaggaatt tattatgaat aaagaacaat
    16741 taaaatctct agtaataaaa actatagatg aaaatagaga aaaaatatta aaaataggtc
    16801 aaggaatata caaaaatcca gaatatggat ataaagaatt taaaactaca gaagctgttt
    16861 caaacttttt tgagcaagaa ttaaatttat ctgtagaaaa aaatatagca gttacaggat
    16921 gcaaagcaga tgcaaattct agcaagaaag gtcctcatat atctatactt ggagaattgg
    16981 atggtatatc atgtaaagaa cataaagatg ctaatgaaat aggtgcttct catacttgtg
    17041 gacataatat tcaaatagct ggaatgttag gtgctgctgt tggtttagta aaaagtggcg
    17101 ttttagaaca tttagatggt aaagtatctt ttatggctac tcctgctgaa gagtttattg
    17161 agttggaata cagagagcaa ttaaaaaaag aaggaaaaat aacttatttt ggtggaaaac
    17221 aagaattaat aaaaagaggt tattttgatg atatagacat atctatgatg tttcatgctt
    17281 ctgatttagg agaagataag gctctagttg gtcctgagag taatggattt gttggaaaaa
    17341 aggttaaatt tataggtaaa gaatctcatg ctggttctgc tccacatgat ggaataaatg
    17401 ctttaaatgc agcaatgctt gctataaaca acgtgaatgc acttagagaa acttttaaag
    17461 agtctgaaag agttagattc caccctatca tcacaaaagg tggagatata gtaaatgttg
    17521 ttcctgctga tgttcatatg gaatcatatg ttagagctag aactataaat ggtatgattg
    17581 atgctaatga aagaataaat aaggctttga tggctggtgg aatggcagtt ggagctgatg
    17641 ttgagataac tgaaattcct ggatatcttc caatattacg atacaaaagt cttgataatt
    17701 tatttaaaaa caatcttgaa gatttaggtc taaaaggaaa agttattgat ggtggagatt
    17761 ttacaggctc ttttgatttt ggagatgtgt ctcatataat gcctactctt caccctatga
    17821 ttggtggtgt aaaaggagct cttcatacaa gagattttga aatagttgat gaagatttag
    17881 cttacataat tcctgctaaa gcaatggcac ttacagttgt agaccttctt tttgataatg
    17941 ctaaggatgc taaagatata ttagatacct ttactccagt tatgactaaa gaagaatatc
    18001 taacattctt agaaaaacac gataaaactt tataagtcta tttttataat agggtggtat
    18061 ctactgtaaa agttatacca ctctttgttt ttgtaacagt atacttcttt tcttttagtt
    18121 tttagattaa actaaaatat attatcctcc ttaaaacttt tagagctacg ttgaaatatc
    18181 agtagaacta tgctatattc tttctaatta atataaattt ctattctaat tcaaggtggt
    18241 gaaaaaatgt ttaatgcagg aaatcgaatt ataaatacat ggttgtaccc tattcaagat
    18301 ggctttgtct tgattgatac tggatatgaa aatggtttta aacatttcaa aaaacgaatt
    18361 tctaaattca acataaaaat caaagatatt cgatacatat ttctaactca tgctcatgat
    18421 gaccatgttg gttttctaaa tcagattcta gacgaatctc ctaatacaaa gattgttatg
    18481 catgataaag ctttagaaat tctatataaa ggtcaaaact cttttattgg tggttgtacc
    18541 agccgtactg cctttctctt ttgccaaatt atgaaactat ttggaaaagg tgagcatagt
    18601 ttttctccac ttaaacaaga atttgaaaaa aggtgtattc ttgtgtctga caagaatcgt
    18661 aaagaaattg aaaaagaact aaatggaaaa attatagata caccaggaca tactgatgat
    18721 tcaatttcac tactaattga tgaaggtgtt ttattttgtg gagattctgc aatgaatgga
    18781 tttccaagta ctcacaaaat taccatattt gcagaaagca aactagaatt tattcaatct
    18841 tggaaaacaa tcatcaatac aaaacctaaa atgatttatc ctggacatgg aaaaccattt
    18901 gaatacagta aattagaaca aaatctaatc tatgtaaata aaataaattt atatcctcta
    18961 cataattcaa aagatattca cagatttttg tagaaaatac aaagtaaatt tatttgatta
    19021 attaaaaaat ctaacacttt actacgctac ttattttaat aacttaatct tccactagct
    19081 tttcataaaa ttttgtttta aaattaattt taaagtgcat atgttattta aatacattag
    19141 ataaaattcg tcattaatct acttaaagca tatttaacta acaccactca accagaaaat
    19201 tcagaaaact gcattgacac aggaaaaagt ttattttata ctttttttag gacatattgt
    19261 ggacacgtct taaatcgaca aacagaattt aaattgtaag attaaccaca atacttattt
    19321 tttaattata tttttaaaca ttagggagga tattatgaat gataacgtag ttaagaagaa
    19381 aaactttttt gacaggacat taaacagaat agaaactgtt ggtaataaac taccagaccc
    19441 agttacaata tttttagggt tatgtgtact tttacttata ctatctagtc tagttggttc
    19501 tatgggtata tcagtagttc atcctggtac tggagaaact ataaccgctg taaatttatt
    19561 gactgtagaa cagcttcaaa ttcttttagg aaacatagtc agcaatttcc aagggtttgc
    19621 tcctttgggt ctagttctag taactatgat aggtgctggt gtatgtgaca aaacaggact
    19681 tatgacagca acaatcaaag catcagtaag caagattcct gaaacaagag taactcttgt
    19741 tgtaatgact ataggtatgc ttgccaatat agcttcagat gcaggtacaa tattatttcc
    19801 accattagct gcacttgtat atcttggtgt tggtagacat ccacttatag gtttattttc
    19861 tggatatgca gcagtctgtc taggatttgc cgcaaacatt atgataagtg tcaatgatat
    19921 acttgctgca agttttacag ttccagcagc tcaaatgatt gattctggat ttcaagccaa
    19981 tgcaacaatg aacttatttt ttatgatagc atcaactttt gttctaatac ttttggcaac
    20041 atgggtaaca gaaaaaattg tagctcctag atttggtaaa tatgaaggaa atgcagaact
    20101 agatgttgat ggaagtctta gtgatgtaga aaagaaaggg cttaaaaaag ctagtataag
    20161 tatattaata tatgtggcta ttatagtagc tcttagtgta atcggtaaaa aaccattctt
    20221 agctgaccca gaaacaggag atttactatc aaacaatgct cctcttatga aaggtatggt
    20281 acctataata gcactagcat ttttcatacc tggtgttgta tacggaaaaa ctataggtaa
    20341 aataaagaag gataaggatg tagtctctat aatggctagt gcaatgagtg atatgggtgg
    20401 atatataata ctagcatttg ctgcttcaca atttttgcaa ttattcacaa atagtaattt
    20461 aggtctgata ctagctgtaa agggcggaga atttttaaaa tcagcaggaa taaatggacc
    20521 tttattgttg ataggattta ttatattatc atgttttata aatttattta taggtagtgc
    20581 atctgcaaag tgggctattc ttgcacctat atttgtacca atgtttatga tggttggata
    20641 caatccagca cttactcaga tggcttatcg tataggtgat tgtataacaa atccacttag
    20701 cccattattt ccgtacttcc ctattatact agcattcaca agaaaatacg ataaagatgc
    20761 tggtatgggt actgtaattg ctaatatgat accatactct atatcattct taatagtgtg
    20821 gactatacta ttaatattgt ttatggtatt taatattcca ctaggacctg gaatacttcc
    20881 ttcatatagc atgtaattta tttaaatctt tctaaaagga gaaataattt atgttagata
    20941 aaaatagact tataaataat tttatggata tggttagaat tgatagccca tctaatcaag
    21001 aattagaaat gtctaagtgg ttggtaaact acttaaaaga aagaaatata gatgccatta
    21061 tagatgatgc aggtgaaaaa tatggtggta atacaggtaa tgtcattgcc tatataaaag
    21121 gtgaagaagg aagtagacca ctttgtttat gtgcacacat ggaccaagtt caaccttgtt
    21181 taggtgtaaa accaatacta gatggtaatg tagttagaag tgatggaact actacacttg
    21241 gtgcagatga taaagctgga atagctgcta tacttgaagc tttagaacat gttattacag
    21301 aaaaaatacc acatagagat atttatcttt gttttacaat ctgtgaggaa gctggtatgc
    21361 atggtgtcaa aaactttaat cctgacaact tgccttgtaa agatatggtg attttagatt
    21421 ctggtggagc tattggttcg atagcataca aagctcctgc tcaacaatct ataaaaatct
    21481 cttttcaagg aaagaaagca catgctggta tagaacctga aaaagggtta aatgctatat
    21541 tagtagcctc tcatgcaata agcaacatgc acataggcag aatagattca ttgactactt
    21601 caaatatagg tgaaatagaa ggtggtggag ctacaaacat agtaactgat aaggttacat
    21661 tgactgctga aattaggtct catatacctg aaactttaga gtatgagctt aatcatatgg
    21721 aaaaatgttg taaggacgct gcatctaaat ttaatactac ttatactttt gaacataata
    21781 tgtcttaccc tagttttgaa cttagtagag atagtcatgt tttcaagtta agtgaagaag
    21841 caataagaca agttggtgtt gttccaaatc caatggtaat tggtggtgga agtgacgcaa
    21901 atatattagc taatcttgga tataattgtg ctatattaag tctaggtatg tatgatgtac
    21961 acacagttaa tgaatatgta aatatagacg aattatatga tactgccaaa atagtttatc
    22021 atatgattaa attataaata tcataataga actctttaaa ttataaaaat aaaaacctat
    22081 gtatcctcaa ctttataagt tatatattag agttgtttta cataggtttt agtattttta
    22141 tataataatt tgttttaaca tttttcataa taagctttga tattttatat agtaatttgt
    22201 tctaacattt ttcataataa gcttcaatat tttgcataat aatttattct agcattttta
    22261 ataataggct ctagtatttt atattaataa tttattctag tattttacat aattatttgt
    22321 tctaattttt ttcataataa gctttaatac tttatatagt aatttgttgt agaattttat
    22381 acaatataat gatttataca gttttataaa atatcttaaa acagtatttc agtaatattt
    22441 tttggtcttc ctccaccaat actagtctct tttgcacata ttcgacctaa acctgcattt
    22501 actattttat ttaatatacg tcttgcactt ctttcactta catttagata ctctgctaac
    22561 tcttttgaat cataaatctt actttttcta ttctcattta tagcaataat ttttgcaact
    22621 gactcacaac tcattccagt ctttttagat atttcgatta ccttttcatc agatagcatc
    22681 aaagaataat ttaattcatt ttcggaagct aaaggtcctc ttatgttttc atcttcatct
    22741 accaaatata taccaatttc ttttgaatct atggagtgtc ttaatgcttt atgtgcatta
    22801 ttttcagcct gatacgcagt tactccagta ccaattccta tactaagaga aaagcccatg
    22861 tcttttatct ctctctttag attgaatagc ttatcataat tatactcatt atcagctacc
    22921 cctttatgaa caaatacaac ataatcattt cttccaagta aaaataagga accttgaatg
    22981 cttcttacat agtttactac aagcttatcc atatctgatt tttttatcat gtcagaataa
    23041 tagttatcta tcttctcttt ataatctatt aaactcaata tttcaacagc aatttgggaa
    23101 aatcttgcct tacttagagc atattcactc tttaccttgt cataactttc tttgattaat
    23161 tgtatagtag cttgtaaacg aaatacagga tagcctcttt cttttaattc attatatact
    23221 gcaccaaaac cagtcaacat tatatccgtc ttattttctt caaataattt tatatgccat
    23281 tctacaagtt cagactctcc tacttccaaa gaaaatggat tacaaaatac actcgttgct
    23341 ttaatatcaa attctttaag tgcatcttcc acaacatatc tatcaactac atctatactg
    23401 aatttatcta attttatatt tgcacttttt attgcccaaa atgccttcat tatactcgtc
    23461 ccacttctcg gtacaaatga atgtggctta cttatctcat acttagattt tataaattca
    23521 taaactgcac atcctgtaaa tataatagca tcacattcgt cttcacattt agaaataact
    23581 tctattgtat ctactacttt ttctcttaca tatattttag tctttaaatc actgtctatc
    23641 tgttttaaat catcctttat cttaaaccca gagtctgaag gacctataat acccactatc
    23701 ataaacttcg ctcctaatcc ataaatatta tactttttaa aaattatatc ctcactattt
    23761 tctacttcta tttaattatt ttgaactact ccatcctacc tacatttaga atggaataat
    23821 tagcttattt ttgataaagt aacttctcaa aatcagcact tggaataggc ttacaataat
    23881 aataaccttg aattaccaca caatctaaag tcactaaaaa ttcagcttgt tcttttgtct
    23941 ctacaccttc tgccactaca tccatatcta aatcttttgc catggctata gtgtgcttta
    24001 aaactatttt ttctctgtct gtgattcctt cctcattaaa gaaaccacaa tctatcttta
    24061 atgtatcaat attaatattt tttaacatat ttaatgaaga atatgctgaa ccaaagtcat
    24121 ccatatttaa aacaatacca tccattctaa ggtcggctat tatcttagta aataatttta
    24181 tatttttaat aaataaactt tctgtaagct ctaattctaa aaaagatttt ggtatactat
    24241 atttatttat taaacttaaa acaatttctt taaaatgtgg attatgcaaa tgtaatcttg
    24301 atacatttac agagatagga actggctctt cacctaaatc tatccatttt ctaatcaaag
    24361 aacatacttg ttcccataca tacatatcta atctgataat aaacccattc ttctcaaata
    24421 gtgaaataaa tttaattgga ggtattatac ctttttctgg atgaacccat ctaaccaatg
    24481 cttctgcacc aacaatttta tttgcattaa gattatactt aggttgtaaa tatacatgga
    24541 attgcccatt ttcaagtgcg tattccattt ccctttccat ctgtttttct tcaagtgcat
    24601 catttcttat agtatcatca taaaatatat agttattgat actttgtttc tttacttttt
    24661 tgtgagcata tcctgccatt tcacacgcat ttgtaattgg aatatgatta tccaaaattc
    24721 tataaacccc aaaacatggt actaacatat attcaaattt ttttctattt aagctatttt
    24781 taatcttata aattacctta tgaatatctc tatcagagta actctcataa aaaatgcaaa
    24841 atacatctgc atacatacga caacatatac cattagaacc aatgtttttt tgaatcaact
    24901 ctgcaacata tattaaagct ttatctcctc ctctaactcc ataaatgtca ttaattacct
    24961 tgaacttatc tatatccatc attataattg cataacgctt gtcaggatat cttttaagca
    25021 ttaaacttat ttgttcacaa aaactttcat aattgtatag tcctgttaat gtatcttttt
    25081 ggtttttatg tagttgcata agataatcta tattttttat agcaactaaa atatgtgttt
    25141 gtttctcacc taacttattt ttactactaa tctttaacat ataaattaat gcccaatagt
    25201 actttttatc tattcctaaa cgtctatact caaaatttag ttctaaatcg tcttgcttgc
    25261 tattattaag actatcaaga gattttagaa ggtggttatc attaaataat attatatcat
    25321 caggatgaat taaatgtttt tttatgtatg aaaaagtttt ttcaagattt tcctttatag
    25381 gaaaactaaa aatattgctc tctgattgat aaattggagt aattaaattc gtatcaatgc
    25441 aaatagataa aattatatca tatgtattat aagctaattt ttcataagcc ttagaatacc
    25501 cttttatcat taaatcatca aaataaacct tatcaactaa ctctttatgt ttaaataaaa
    25561 tattattcgt cgaatcagct aagtcactaa ttactttcat ttcattattt ctaagtttgt
    25621 tcttattata atacctcttc ttatcttggt acattctctc atcagcaact ttaattagct
    25681 tatgtatatc aatattatcg tcactccaaa tactgcccac tgctacacta tatatcatct
    25741 catccttaaa ttcttcactt aaccaactca ctaattcttc aaatagttgt tttgatatat
    25801 cttcacataa tacaacaaac tcatctcctc caatacggta aacattataa gaatgaaagt
    25861 atttttttat tattacacat gctgacacaa tagcagaatc gccattagca tgtccaaagt
    25921 tatcattaat atcttttaac ccatttatat ctacaaatac aactcctatg gatttaactt
    25981 ttcctttttg aaaattatct atatacttaa tatatttatt tctattatat gcaccagtca
    26041 agaagtcata gtagctcata taatttaatt tattttctac ttttcttttt ttcatctcag
    26101 ttaataaaaa ataagatagg gatgtcaaaa gagaggtatc tccaacagct ttatgtggat
    26161 tatcaactcc aataaaccct actactttat catcttgttt tagtgaagat gtcattaaac
    26221 tttcaatttt ttgaggtttt aaaatttcat attctattgg ctgttcttct tttatatttt
    26281 ctatatcatc aattattaca aaaccttttt gttcgaataa taaaaaccaa ttctttaatt
    26341 cattaatatc aagatttgtt agtgcctgtt tttgttcatc aacaccttca ttgcaccatt
    26401 catatgtatt agttactttt tttctatctt ctgatacttc aaaaacatat gctctatcag
    26461 ctttatgaaa tttaccaata ttggttaata caagatttac agcatcagaa aaattagatt
    26521 ctgttataag atgtttaata catccaacta ataactcctt tatctctaat ttttctgcta
    26581 ttgacttact tatatcttcc ttttctgtaa tatcaagagc tatttctaat cgtgcatgtt
    26641 tgccctccca tttaattaac ttgtccttta atataaaatg tctatttgtt cgagtattcg
    26701 tattttccca tatgtaatat tcatcttctt ttaaaataga gtttgtacaa aattcgcagg
    26761 gagaatcttt cccctgtaat gctttataac attttaaatg ggatatatca ttaagtccca
    26821 ttgccttttt cccaatttca ttaatatata aaagttcata tgtatctaaa gaagaaacat
    26881 atacaatttc atccaactca tctattaaat ttattacatc catttatata tatctccttt
    26941 tattcatttt ccagattgaa tttttaaagc ttttaaaatt ttgctatata tttggcaatg
    27001 atattatatt tctttatgtt ttaaaatagt accttaatga ggttctattt tttagtaaat
    27061 agaattatta ttgtgtcaat cgtacaatag agttttgtaa tacctaattt aatatattta
    27121 taattaatta tctcattatg tgtttataat taattctcat ataaatgaca aatctccacc
    27181 tcaattaagt attccaatca tatatgaaga taatacttca ttcatttaaa aatataaaac
    27241 tattatatat taaaatttct tcaataataa attatctaga ttgttacttt gatatattat
    27301 ataatatcac aaaggctgat ataaaaagac aaaaagggca atttttttat atcaaaaaaa
    27361 aatgttaaat tgatattatc catatataaa ttgatattat ccatatagat gctatattta
    27421 acaattctac ttacttccct tacacttatt agcatatagt tattaagagt ttgttgcaaa
    27481 acaacactta gcacacttta aaaagtgtgg tctaataagt aatcaacgaa gaagacataa
    27541 taaagcataa aatatgatat acttttccac gccatcaaaa ctgaggattt tattattaat
    27601 atatgctaaa atatgcttaa taaattaaat tttaatggga gaatagttat gaaaatattt
    27661 agtttcttgt tgtttgtgat aggaatatgt ttatgtattg ctggatttat aggacattac
    27721 ccagtatttg ttggtacaac attgagtttt cttgcaattg caatgatagc tgtaagacaa
    27781 gtcaaaacta agaaaaaaat gaaataggca aatcctaact ttacaagtta atattacaca
    27841 agtaattagt ctaaaattgg atactttttc tattacagaa atacatcatc cactttgtat
    27901 tttcttaaaa aaataaaata gctatgtaaa ttcaagatta gatagattaa ctctctatcc
    27961 atttcattgt aaaatataca tagctatttg tattcgattt aaaatactta gattttctta
    28021 cataacaaat aatttctatc tgattattac tcatattcat ttagtaacca ctcagcaact
    28081 aatcatttag tatctattca tccgccatac ggtaacctac cccaacctca gtcaaaatat
    28141 attctggctg agcaggattc ttttcaattt tccttcttat acttgccata aaaactctaa
    28201 gcgactgatt ttcactttca tagtaatttc cccaaacttt atctattata aacttatggg
    28261 ttaagactct tcctgaatac ttagacatca actcaataat cttatattcg attggagtta
    28321 aatgtatttc ttcaccatta attgacacaa tatgattttc ataatctatc tttaggtttt
    28381 taacttcaaa agactttgga gcatcattat ttatattatc ctgttgagct ttatttctaa
    28441 gagccacacg tactctagcc aaaagctctg ttacactaaa aggtttagtt aaataatcgt
    28501 ctgctcctcc atctaaagct tccaccttat ccctctcatg ctctctcgct gaaacaacaa
    28561 ttattttatt agtctttgca catgccctaa ctcgtcctat tacctcaatc ccatcaatat
    28621 ctggtagtcc taaatccaaa attatcaaat ctgggtcaag agaatgtata agtgatatag
    28681 ctgttcctcc attatctgtc tctacacacc tataattttg agtttcaaga gatactttta
    28741 taaatttaca aattggctta tcatcttcta caattagaac taatggcttt atttccactt
    28801 gtctttcccc tcctcatcat acataggtat gctaaatcta aatgtagctc ctccagaagg
    28861 attattaaag gcgacaattt ctccaccatg agcttctact atagatttac atatctccaa
    28921 tccaagacca atacctcttc tttcaagatt tctagactta ttcttagtat aaaacctatt
    28981 aaaaatattc ccgatatctt catttggtat tccttttcca ttatctgcaa cttcaaatag
    29041 tacttgattt gactcttttt ttacagttag ttctatctta gaatttttag gtgtatgcct
    29101 tatagcatta tcaattagat ttactaacac ttgttctatt aataatacat ccacatgaac
    29161 gattattatc tcatctggaa tatttgtttt tatgtctcta ctattggcaa actttttgac
    29221 tcttaatata gattcagcta ttatttcatc aacaacttct ggtcgttttt caatatccaa
    29281 ttttccttca tctattctgg tcatactaag tatattctca acagaatgag ttagccaact
    29341 cgtatcttca tatatatttt tcaataattc tactctagtt tctttatcta tcacatcatc
    29401 attttcaagt attgttgaag atgaacctaa tatacttgta agtggagttc ttaaatcatg
    29461 agaaattgac ctaagcaagt ttcctcttaa tctctctctc tctgcctcaa gatttgcttt
    29521 tttatttttc tcaaataaat tttctctatc aattgccaac gcaacctgtg ttgaaactgc
    29581 ttctaatagt atcttttcat tttctgtaat aatatctatc ttaaaacacg caacacctat
    29641 aacaccaaga acatttgatt cttgaccttt tatagggaaa taatatgcac tgctgttttt
    29701 acaatatttt gtcccaattc caactgggtt acctgtccta aaagcttctt ttatagcttc
    29761 tttttctaat actgaatgga atatattctc acttccatca ttgttacaaa tataaatact
    29821 tggcttacct agattattat tctcatctgc aatagtcact attacagttc tatttaatat
    29881 atttactaaa ttagacccac aaaattcaat aatttgattt ttattttttg ctttaagcaa
    29941 cgttttgtta ttctcataga gcaatcttat cattttttct ctcttatgag aaagtctcac
    30001 ttctcttttt atcctagaag ttaaagtact tgttataatt gctgccatta gcataataca
    30061 aaaggtcata ggataatctt ttctataagc taaaaaagta tataatggat gcgtaaagaa
    30121 aaaattaaat gatagcactc ctattactga agaaagtatt ccaaaaaaat atccataggt
    30181 tatacttgta gcaaatagta cacctaatat gtatactagt ataatattag attcattaaa
    30241 acctaccttt tcaaaaacta ctgatattcc agtagcaatt gtcataacca atatagtttt
    30301 tatgaagtcc ttaataatta tctttttact gagatagcca tcttcatcat aatcatactc
    30361 ttttaagtct tcatgttgta gtcgttcctt tttcatttac tacaattcct ccttattgtt
    30421 actgtttaaa ttggctctat tttatataat acaattttat cataataaat tcaatcaata
    30481 catttaatta atgtacttaa attactaaaa ggtgctgtct taaaatgaaa ataaatctct
    30541 atttcaaaac agcacctata tatttaaatt actaatttag tttttacata cttaaatcaa
    30601 tagttttatt caatttcata aattataata cttcaattat aaaacatttc tatccaacaa
    30661 gcataaatat aaagtgggca catatacctg cacataaacc acctatagta tgcgaaagta
    30721 tcgctttacc agccaatggt cttgcatcta aagcatccat catacctatg tgtgtactta
    30781 aatatccact ccaacacata cccattgctg tgaatactgc tatatcatta ggagttatag
    30841 cgcctgattt tataaactct ggtactaaag atattgctgc tccaacagct cctaatgcag
    30901 ttacagggaa tgctattgcc tctggtgatg tgaatccaaa taatggttct attatgaagc
    30961 taatcttatc accaatagca ggtaataatt ttataccttc atatgcagct cctgtgtaaa
    31021 cagcttgacc tgtagcaggg tctgtagatg gtccaaaagt taataacata actaatgtac
    31081 aaactactaa aactcctggt attatagcca tacccatttc aacacctaac ttaccacctt
    31141 caagtatagc atccaatgtt ctttggaata cattaccatc tcttatttct ctaaactctt
    31201 caagttttgc acctttatca tttatttgct tttcagtatc atttttaggg tcataattat
    31261 aatacttttt agtaaaagtc aacataattc taacactaat aatactacct attattgccg
    31321 caacattacc tattatagct ggtagtacat attctttacc ttgagctatc ataaaagttg
    31381 ttacaataag tcccatacca aaggctgttc ctaaattaca taaagcaggt acttgatact
    31441 tcttaaaata ttgtgtaaat gttttgtctt tagcaaatgg tataatagct ggattatcag
    31501 ataaatatgt tgcaactact cctgctatac tagcaccagg taagccccat ataggtctca
    31561 taagaccctt aaatatctta ttaactaaag atattactcc aaactctgaa agcaatgcac
    31621 taagtgcacc tgcaagaact gccatagcca ttattaaaaa tactgtgtct aataaaagcg
    31681 catgtgctgt actcattatt actttaaaca tcattcctgc acccatgatg cttcctacat
    31741 atccaaatcc taccgccaat agtacaataa atacgaaggt ttccatactt actgccttga
    31801 ctcttctctt atccgacagc ttttccatct tgaaatcttc ccccttttaa ttttaaatta
    31861 aggttcctaa cattggtaca aattttttgg tacaaactga gttctaaaac ttacactcgt
    31921 aatgcaagtt gtcagttttt tgaaataaaa aaaaattacg tttatagaat aagaatatcc
    31981 tctttaattt ggatactctt attctatttt atgttattat attatcatcc ttttgtttaa
    32041 aagtcaattt tttctatttt tgttgtttaa ttttatttat actcttttta tatttttcat
    32101 tttcttttat ctttgtaagt actccatata agttgacttt tctaaataca gtagttataa
    32161 ataccaatcc taatgcaatt gaacttgcac acgataatgt actcacccca tattctacag
    32221 cttttatata attattggtc aaaacagaat acatagtatt atatattcca taacctggta
    32281 ctaatattat taaacagcaa acacttaatg tagttgctgg agtcatataa attcttgcac
    32341 ataactcaca atatatcgca aaacaaactg tagctataaa aaaacataag ttttctgtta
    32401 ctcctatatt taaaagaaat ttatatgaaa accaagctat acttccacct attcctgcta
    32461 gtattaagtt ttttcctttc atattaaata gcactccaaa gcttaaggca gtaaaaaaag
    32521 ctgctattac ttctataaac aaatgcactt atatcccccc taacttgaag tacaatccaa
    32581 gtaccaagaa cattcctact gctatagata cacctacaaa aaatacttct gctaattttg
    32641 caagaccaga aatcaactgt ccatctaaca aatctcttaa tgcattagtc aaagcaagcc
    32701 caggaactaa gagcattatt gctcctgcta ttaaatggtc taacgtcttt atgaatccga
    32761 gctttaaaat taaaattgaa caagaagcta taataactgc tccaattgca tttacaaaaa
    32821 agtcattaag ggaagattta cttaaataca taataacaaa cttagtcaga atcccaacag
    32881 taaatgcagc tataaattct tccacatttc ctccaaataa tatcgaaaaa gttgctgctg
    32941 caatacctgc aaaaaatatt gttattaaat ctgagtaata gttatcttca cttatttcat
    33001 ctaaaatttt ctcacataat tcaatatcta aattatttat acttattgct cttgataatg
    33061 agttaacttc atgaaccaag tttaggtcta ctcttcttga gcttattctt ttaattgctg
    33121 aatgtaattt cccatctaca aatacagatg ccattacagc tgttggagtt gcaaatacat
    33181 ctacgtggtc tattccaaaa gattgacata ttctagctat cgtttcttca actctatagg
    33241 tttctcctcc actttgcaac atagctttac ctgcatttga ggaaaagttt aaaattctat
    33301 ctatatccac aaaacatatc tcccattctt ttatagtatt attcatattt taatacaaga
    33361 tattatttat ttaaactatt ttaaataatt catatccaat atttacattt tatgaaaaaa
    33421 cttgtttttt atgcttgtca aaatcaaatt ttaagcttgt ttacaccata aaatggctga
    33481 attaatattt gacaaacact ttcaaccatt tatataacct tctaaattgt ataacttttt
    33541 actacaaata aaattatatc tcttttaatt ctttctcttg agtatttagc ttatagtaac
    33601 ttcatattta tatatgtaca atataaaaca ttatttttat gatacaaaat ataatttgta
    33661 aatgtatata tgtattaact gtgtatatat aaattattct tgaccttatc agttttttca
    33721 tatatcttca tctataccaa ccatatatta ataaatgata ttacatagac ttaagtatat
    33781 taaaaaactt aaatttagtt atttaacaac ataatactct aatttaatct ataaaaatcc
    33841 atacttaata taatgcaact cttattttaa caccatctat tacacaaaac aacatattaa
    33901 aaagtaaaat acaaaatatc cactataaac cttattttaa tactgaatat atattataat
    33961 atatttaatg tagcttaaat atagtttaaa cataaagaaa ggaaacggta tatgctaaga
    34021 aaagataaag ttctattatc tctacataaa ttatgtgaaa atatgacttt aaaagacctt
    34081 caatcagata aaacaggatt cactacaata gaaattgcta accattcatc tcttgataga
    34141 agtaatacca gtaaagaatt aaataaccta tacaatgaaa aaaaagttct gaaaatatct
    34201 ggtaagccaa ttttatttct acatgctagt attatagaaa atttaattgg ccgtactttg
    34261 aacagtgatg aattttctat aaataattgt aatgagctac ttaaatcaag taaaaatgac
    34321 tcagaagata ttttttcaac attacttgga catgattcta gtcttaaact acctatagaa
    34381 aaagctaaat ctgctatact ctatcctcca aaaggtctta atacgttact aataggacct
    34441 actggtgttg gaaaaagtac atttgctgaa acaatgtaca aatatgctgt agaaagtaaa
    34501 atcttttctt ctgaaagcaa attcgtagta tttaactgtg ctgaatatgc agaaaatgct
    34561 aacttattat taagtaattt atttggttat gtcaaaggtt cttttactgg tgctaataag
    34621 gataaattcg gcatagttgc acaggctgat ggaggcatat tattcttaga tgaaatacac
    34681 agattgccac cagaaggtca agagatgctt tttcttttga tggacaaagg catatacaga
    34741 cgattaggag aatctgacat tatgcacaaa gctaatgtct ttattgtgtg tgccacaaca
    34801 gaagatatac attcttctct gcttgggact tttttaagaa gaatccctgt tacaatcaac
    34861 ctacctgctt tacaggatag gtctttaaaa gaaagattat ctcttattaa atacttcttt
    34921 attatagaat caaaatacac caatgcaact ataaaagttc acaaagatgt aattaaatca
    34981 ttactccttt atgattgttt tggtaatata ggtcagctta aatctgacat acaacttatg
    35041 agtgcaagag ccttcttaaa ttacaaaact ggacttaagg ataatataga aatagattta
    35101 tcccttgttc ctgattacat ctatattggt cttttaaaat tgaatgaaaa tcgtagtaat
    35161 ctaaataaat tatcagaact tgattatatg cttttttatg aatttaatgg taataactta
    35221 gaagttgaat atacaaaaga actatctaaa tacaatatag atacatcaaa caatggattt
    35281 aaatactcta cagagattcc ttatctggaa aatgatataa ggagtatgtt tataaattac
    35341 atggaaaagt actctacaaa attactttcg atatcttcag taactcattc tgattataca
    35401 agtaatgaga tttttaaagt aatcaatcca aagatttact atgctgttga acattcttta
    35461 aaagaggctg aaaaaatatc gagaaacaaa tacacaaaac aaacttatat tgctctttca
    35521 atgcatataa gtgcacttat agaaaatata aatcaagaca catataatcc taagtacaat
    35581 ttatataatg ataaaatttt cttagataaa gatttaaata tagctaaaat agttttaagt
    35641 ataattgaaa atgacttaca aacatcttta cctaaagatg aagtaaaatt tatatccatg
    35701 tttctaaata gcatgtatct tgaaccaaac aatcaatctg aaagtatagg agtcataata
    35761 cttgctcatg gaaattcaac agcaagcagt atgtgtgatg tagcaaattc attgcttggt
    35821 acaaaccatt gtaatgcaat tgacatgcct cttgatgtaa aagtaagtac catacttgat
    35881 aaaactatag agttggtaaa agaatgtgac gaaggtaagg gtgtacttct tttaacagat
    35941 atgggctctc ttatagcttt tggagaactt atttcagaaa aaacaaaaat caaaactcgc
    36001 tcaattgaaa tggtatctac tccaatagtt ttagaagcag taagaaaaag tacactacca
    36061 gaaatgactt tggatgaatt agctaattcc ttaagctctt taaatccata tattggacga
    36121 gcagcaatcg attcaacaga aataaactat cctgaaaagt caagagagta tgtaataata
    36181 actacttgta taacaggata tggttcagct atgaaagtag cagactttat aaattcttca
    36241 cttaaaaata ttagtaaata caatattaat ttagttcctc ataatataga aagttttaaa
    36301 atgtataaga ataaatttag taatactaaa attctggcag ttgttggaag tgtagatttt
    36361 aatgtagcca acaccccttt tatacacata gaggaactac taaatggata tggcctagat
    36421 atgctaaaca aaataataga aggtacattc aatgccaata gtattacaaa tataaaagaa
    36481 acaaatctat catacaacag tttaataata aactttatga cccaaaactt agagcttttg
    36541 gactctgtta aattattcaa ctatgtcaat tcttccttat ttacaataat agaattaata
    36601 gatgaaaact taaagagcaa atttaagcta ggatatatac tacattgctc ttttatgata
    36661 gaaagatgtt ttaaaaatac aacttttcca tataataaca ttactgaatt aattagtaaa
    36721 aatcatgaac tatatagttt aatacgtgaa gcctttaagc caacagaagc ttattttaat
    36781 attttgatac cagacgaaga aattgcttat ataatagaca tgattaatga gtatctaaat
    36841 aaataaaatt tatagcactt attttgtgca tattaattaa tatatgaaat ggaggacgag
    36901 attttgaaag gaaaaataaa acagttaaca atacttgcat taatttttat atttataact
    36961 cctgtatttg catttgcaga tactccacca gtaccaaatt cttcaagagc agcactactt
    37021 atagaccagg aaactaaaag aatattattt gaaaaaaaca ttgatgaaaa aatgccatta
    37081 gcgagtttaa gtaaaatgat gaccttttta ttggcaatag aagcagttga taaaaatcaa
    37141 gttaaagaga ctgatatggt gaaaatagac aagtctacag cttcagtagg aggttctact
    37201 tgtaaactta aagatggtga tgaaatatct ctaggagagc ttatgcaggg tctaatgcta
    37261 gtatctggaa atgatgctgc tatagccata gctaaacata ttggtaaaac tgaaaagaat
    37321 tttgtaaata tgatgaacaa aaaagcagaa gaaataggaa tgattgatac gtattatttt
    37381 aatccaaatg ggcttcctat atatactgac ccagaacata aagaacctcc tattgaaaat
    37441 atgtcaactg ctcacgatat agttacactt ggaaagtata tgtacgacca ttatgaaaat
    37501 caagttacaa gaataaccac tatgcaagta tataatgata ctaaaaagga ttttacacat
    37561 tataacacaa atcctctgct tgtttcagta cctggtgttg atggaataaa gacaggatat
    37621 acagataatg ctggatattg ccttgcattt tctatgatgg tacctaaaga tgctaaaaac
    37681 gaaagaaatc atagattgat aggtgttgta cttggtgatg gtaacaagaa aaatagaatt
    37741 tcttcttccg ctactttatt gaaatatggt aaagataatt tccattctaa aaagatagca
    37801 cataagggtg atattataga gactccttgt gttgatggta ttgatgattt taagataaca
    37861 gttaaggttg ataaagattt gtatggtgtt gtttcagata acgaaaatat caatcctaag
    37921 gtagtgttta aaaatatgaa ttatcctatc cataagggag atattgttgg tgttgcaaag
    37981 tattataatg actctggtaa atttgttgga agtgttgatg taaaaagtga aagtaatata
    38041 ggatgtattc ctttgaagga taagattaag attaaggttg ctaagataaa taaaaaactt
    38101 gagattaaaa attctgtttg ttttaaagca tagtaaagca tattattaaa agggtatgtt
    38161 aaatttataa agactccact ttgtggagtc tttttgtttt ttacaaaaaa ttaaaatagt
    38221 ggcaacaatt gaggatgtga gggagagttg ccactatttt gtatagggta ttatattatg
    38281 tttttaagct agttttacta tcttctatgt ttatataata actcttgtgt gtgaatttaa
    38341 ttgataatta atatgaaaat tatgtgaagt tttgatttat ttgtaatata ttctactact
    38401 attataattt ttctactgga tatactaatc atttgtttaa cattatctga gattgatttg
    38461 caaactttta tataactaaa ttagttatat aacttataga ttccattaaa taccctaata
    38521 atcatatatg tacatacaaa gtcatgctta tgcaaaatct gcagtttcaa ctaacttatt
    38581 atataaacca tctttatgta gaagttcagc atcatttcca gattctatta ctctaccttt
    38641 atctaataca tatatattat cagcactctt aattgttgaa agtctatgag ctattataat
    38701 aactatctta tcttgtatgt actctttcaa gttgttcaat atctcttttt gtgaaatatt
    38761 atctagagct gaagttgctt cgtccagaat aagtaccttt ttattactta ctaaagctct
    38821 agctattgat atacgttgtt tttgacctcc tgatattttg acaccttttt ctcctactac
    38881 ttcgtccaat cccttatcta gattttttat aaaatcatct aaacaagtaa cttctaatat
    38941 ctcatctaat tctttatcac ttattttatt atttaatact atattatttt ttattgtgtc
    39001 atcaaataca aattgatctt gagttactat atcaatatta tttcttagtg attttaaatt
    39061 aatatccttt atattaacac catctattaa tatatcacct tcatttatat cccaaagtcg
    39121 gtatattaga tttgttattg ttgatttgcc acatccactt ccaccaacaa ttcctgttac
    39181 ttcccctttc tcaaattgta aatttatatc atttaaaaca aggtttaaat cctcaccata
    39241 tctaaaagat acatttttaa aatctatttt cttaatttca ctgttatcta ttctatatcc
    39301 attattatca actttaatat ctatcttttc atctattact gaaaatactc tattgataga
    39361 cacttttgat tgtgctattc tagtattcgc ccttactata gctatacatg gtccaattaa
    39421 cattcctgta tattgttgaa atgctattaa ctcccccatc gtcatcttat tatttattat
    39481 tttatatccc ccaattccat atattaatat tgttatcaat cctgttagta tttgagatat
    39541 tgctatatta ctactcataa tgatgttcaa attcaaatct ttttttatca aatctctctc
    39601 tctctttaaa tacttattaa agaaattctt ttttgaattt aatataacaa tatccataat
    39661 attagatacg tactcttgaa tcaaatttga taaactgcct gaatcacttc ttatttcaga
    39721 aattttctta gatataagtt ttgtcatttt attttgagaa aatgttaata tcaactgtaa
    39781 aaataaaact actaaaaata aatcaaactg caaattaatt aagaaaatta acgatattat
    39841 agctgtaaac acatttacaa taatatcaaa tataatctct gctccaaagt tttctatcat
    39901 aaatatatca ctttccataa tggataaaat attacctgtt ttcttacttg aataatatct
    39961 accagaaagt tttgatatat ggttaagcaa ctttactttt agatttatag taactttatt
    40021 ttttattgaa gtatataaat atgataatat aacatcaaat gtagctgata atatccttat
    40081 aaaaatatat atcaatatta aatttataag cagaaaaata tttttatttc ctattccatc
    40141 atctattata catctaatta gttgaggtat tacaatattt acgccagcaa ttataaaaac
    40201 cattataaat gatactatca acttagtctt attcttatat actattatat ttagtattct
    40261 aaataaatta ttattaatag tttttttcat ctatttttcc atcttttata gttataattc
    40321 tatcagctgt ctttgcaata ttatcattat gagttatcat aactagtgtt tgtttgtact
    40381 ctttaacaca ccattcaagc atattcataa cttcatttgt agtcttacta tctaagttgc
    40441 cagtaggttc atctgcaaat attactgacg gtctattggc taaagctcta gctattgcaa
    40501 ctctttgttg ttgacctcct gatagttcat tcggatattt ctttatttgt ttttcaatcc
    40561 ccaacttatt aattaatctc ataacatatt ctttatcttc ttttttccca tcaagcaaca
    40621 caggaagtac tatattatca tatacattta taactggtat taaattgtaa ctttgaaata
    40681 tgaagccaaa ttcctgtctt cttatttcag acagcttatc atcatttaat gtatataaat
    40741 ctacatcatc taagtacaca ttccctaaag ttggcttgtc taagcctgca acacagtgaa
    40801 gtagtgtact tttaccagaa ccacttgcac ctacaatagc tgtaaattta tgtggctcta
    40861 tatctaaatc aataccatca agagctctaa cttcattctc atattttcca tatatttttt
    40921 ttaaatcttt taccttaagt attttcataa cgtatctcca ttcccattta aaaaacatat
    40981 atttttaaat taaattttcg taaataagat ctactgccat atctaaattc tctaattgat
    41041 ataagtatac ttctttgtag tcaatactaa tattaaactc tttatttaaa atagttaaaa
    41101 aattatatgc attataattt ccaatacatg taaaattgtt aaataaagaa tattcactta
    41161 caaattcaaa gtctattttt attttagaaa agtttctatt tatcacattt attattttcc
    41221 ttgctatatc caatcttatc aaattagatt tataacttgg agtgttcaag ttttctattt
    41281 ttaaatcttc tttacttttg cttttttgaa taagtatttc ttccaattca ttaaacttaa
    41341 tatatggatt gttttttaat atatttgcaa caatgccagt tgccactgca caagccttac
    41401 tatttttacc aaaatgagtt actttatctt taaatttaat aaaattatct tttgaatttg
    41461 catacatttg aatcttattt tctggttcgt atatatattg attattttta tatatatttt
    41521 cattacctac tacaccaata acactttcaa atatagtagg aatactttct ttatcttcat
    41581 atttattatg ttttgaacaa ataataaatc taccttgact atttaaaata ttacaaacct
    41641 tttctaattc tttttcatac atactattaa tagatgcagc tgaaatgttt attatctgta
    41701 tatccgacat agtcaacttg ctcagtgtac taagaagatt taaagaactt gtttttccag
    41761 aatcattaaa tatattaata ggataaattt gggtattttt acttatattt aatatggttt
    41821 tcgatacaaa agttccatgt ccatttatgt catttatttc cttccccccc aaatctttca
    41881 attgaaaatt tgaatcataa acataatttc cattaatatc atcatcattt acatctaatc
    41941 ctgtgtctaa gactgctatt cttactttag tcaattaata atcacctcta aaataaatta
    42001 ccttgaatat aaaactaatc cttaccataa tataggttcc aagatgtttt tcattttttt
    42061 acaatttgca tcaaacattt ttttgttatt ttttaaagta tatattttcg atggacaagt
    42121 tgtacaaaat aaatttactt tacattcttt acaactctca atatttactg gttttaattt
    42181 atcaaatata ttaaatatat ccatttctct attaagaatc ctctctaata tgttttcatt
    42241 aaattctaat atattgaata tctttaaatc cttatactct aagtttggac acggatatac
    42301 atctccttta tgatctatac ttatctgatt aacacctgct ttacacatat ttgaacataa
    42361 actactttca tccacataat catctttgca aatgtaatca atatcaagtt tatcattaag
    42421 atatttgcta tagttctcat tacctctacc aatattcata aaatttctta ttataggcgt
    42481 tgtacctaaa tcttcattta atttattgaa tttctctatg tctttctcat tattctttcc
    42541 taccaccata gacaaaccta cgttctcgaa tttttttagt tttataagtc taatcacatt
    42601 taatacttta cagaatactc ctttacctct tacttcacta caacttaatt catcataacc
    42661 atctaaacta atttctattg catataaacc attaattata tcatcaatct gtttttcttt
    42721 aattaaagtt gcatttgtag acagaattat tttaccttta aatttttctt ttatataatc
    42781 caacagctct aagaaatcat ttctcatcaa tggctctcca cctgtaatgg ttaatatcct
    42841 tggatttaat ttaactatat tatctattac ttttcttact tgagatgtat ctaaataatc
    42901 gttattatct attttagaat ctacacagca ataatcacaa cttagattac atctattagt
    42961 tggagaaaat gaaattttgt ttattctctc tagtctaaat tcacttagaa tagaatcact
    43021 tagaagtcct atatgctcta acttatctat aactcgttca taatattttt tatcttcatt
    43081 ttcttggaat acatcataca aattaccaag ttgtaatgca ttatctactg aatactttag
    43141 aacttcataa cattctattg gaattttaac ccatcttcca tttactttat tactaagaat
    43201 aacttgatta ttatttatta ttttttcaca tatacaatct aaaaaatatt tgtttgagct
    43261 attcatttat tttatttcct tcctatatat ttaaattaga aatttcatta attttctttt
    43321 ataccactta ctatactaag tttatttatc attttattag aaaaataaac tgcaatgaca
    43381 caaacaaaaa cagatataga tccaaatatt agaatttcat atattggaat ttcaaattta
    43441 atagagttat ttataccata tacctgttga ttaagtttgt tagtttcaga aactatttta
    43501 taataattga aactagatat aattccagct acaatcatac ttaatacccc atatatcata
    43561 ttttctttta ttaacattct ttttacattt tttttggaca tccctattgc tctaaatgta
    43621 catatctcac tcaacctcac aattatattt gatctaacta taaaaataat gtttatagat
    43681 gatattaata aaactccaaa tacacaaatc attgctaatt tatatgagga tttattataa
    43741 tggtctccaa aatgattacg tacatatctt ccctctatat ctgaaaatcc acttttttct
    43801 attatattat ttatttcttt tattactttt ttatctgttt ctttttttat cttcacaaaa
    43861 actttattat aatcacttat ccctgttaat tcttttaaat ccttttcatt aaatataatt
    43921 tgaattccac ctgattgaga ttctccatct tgctctgata tatagctatt tttcattatt
    43981 ccagcgattc ttacttttgt atttatatat ttatactctc catctttata tacaggaatt
    44041 tttatatcta ttaagtctcc tattttaggt gattttataa tctgagtatt atttgacaat
    44101 ttaattctag aataaaaatt atttaccaat aaaacatttt tataatccct gtctgtataa
    44161 ctataaacat tttcgccttt atctatatat ttatctatat tatttaatag ctctttattg
    44221 taacctcgaa ttaaaactgt agactcatta ttattattta tttcagttct ttttagctca
    44281 tctaaataat cttcttctaa gtcagcattt cttagatatc cttttaaata aatattgggt
    44341 tcaacatctg ttacatcttc aatagctttt atttcattta ataaagaatt atcatattta
    44401 gaaaatgtat aatttgcatt tattggtgaa tatcccaaat aaatatcaaa attgccatat
    44461 gatttacttg ttatattagc tgaatctgac tcttttccat atatgaattt tgtagaagtt
    44521 agtctgccta taaataaaac cccacatagt gatatcgtaa ttattattat tattgatgta
    44581 accttattcc taaatatatt tttaaaagct atctcattta taattccaac aactttttta
    44641 tgtgatttta acaacaaaag cctaggaata taatttaact tatctgtctt ttttatagca
    44701 tcaattatag ataaatttcc agctttatat attggtacta cagaggctaa tataactgct
    44761 ataattgaca tgatgataga ttcaattata gagtttgtat ttatagttaa ttctgcactt
    44821 ttatcatata ctatcatgag acctaagtaa gaaaaaacta tacctccaag taaaccaatt
    44881 actataccta cagataaaac tacaatactc tgaataaaaa atacctgtct aatatttctc
    44941 ttgctagctc caacagctct aagtaaacca atttgcttgg tcatatctag tattattatg
    45001 ttaaacatat tgtatattac taatgttgca cataataaag ggagtaagct ttgctttatt
    45061 gaataagttg ttttttttga aatatttttc atatacatag acatacttac ttctgtattt
    45121 ggataaaatt gattacttgt taacttatat tttctcccta gattcactac tttttgagaa
    45181 tctaaatctt ttgtattcaa ttttaatgta cccatatgag ttattaattc atatggaaca
    45241 atatctttgc cattgtttga atatgtaaaa gctcttacct tatatttatt taaattttca
    45301 tagtattcat cagatttact taaaatacca actattttaa attgcttatc tttactataa
    45361 atagaatttt cattattttt atttatatgc tcattaacaa tctgaaaatc aatagtttga
    45421 tttaatttga catctaattc cattttgtct aaaacttttt gttctattac taattcatta
    45481 gaagttctag gctctctacc tttaactaac ttatatctag tagaatctaa aaaatcttta
    45541 ttgtaagagc ataaatttag agatgctcca ttatctttac ttataatttc tccaaattta
    45601 agtacatcat tgaattcttt tatatcttct tcaccattaa gttcttttac tatatcacta
    45661 tttatatctt cataaaaagc atgataatct cccgagtttt tgtatgcatg atttatatct
    45721 gattgtcctt gagattcatt aataacactt aatgaaaaaa ctagcataac agcaatccct
    45781 atactaagta ttaatgataa agtttttcct ttttgtctct ttaaatatga caccgcaagt
    45841 ttaatattta tcataatcag aatcctcctt attcatattt acaagaaaaa ctctataacc
    45901 taaaatagta ggttatagag cactattcat taaatactaa ctaactcgtt gtgctagtta
    45961 aatttaatta ttaaaaatac tagagttgag aaaatcacat ttcatttgta aaaaactaca
    46021 tctagtactt tcaacatatt taatagactg attagtattt tttaataagc tactgttcct
    46081 tttggagttg atcctgcaca atccaccata cagtctattt gtgaaattat tccatgctta
    46141 tcataatacc atttacatgg atctgcttgc acctcaacat cttgaagttc tattttttct
    46201 tcgatttttt ttatatgtat cataatacat atcccccttt acttttgttt tatatttatt
    46261 ataactagtt aaactagatt ataaactaca tagttttttt gttgtttcca cataaactct
    46321 ttctaatcca caataaattg gtactgcact ttggaattta cctgttacct ttttattgat
    46381 aagtttacat ctggttgaca tacaataatc aagtctagta catccatcac actcttcatt
    46441 cttagatata taaattttta taaggttctt aattttttta tcatctaatc catcatatat
    46501 atttcctagt aaaatatctt tatctcctac acatactgta catggatata catctcctct
    46561 agtatctatt gcataactat ttatccctcc aaaacaatct ccttttttct tatttataaa
    46621 ttgtttatct aaaatagata tatctatatc aggataatcc tttttaatat tcataatttt
    46681 actaatttgt tcatttaata ttttaatatg agaattatcc caatttttat ccataaaatc
    46741 tgaaattggt gcgatatttt taaacccttg ttttgctata tcatatacac tctcataaag
    46801 atacttaaca gtatttgagt tatatgtcat tcttgcccta acatatatac ctttatctat
    46861 aagtcttttt ccattttcca ttactttttc ataagtacct actccgttag catctattct
    46921 atttatatca tgtatattct tttttccatc aatacttatc gatatgtttt ttacattctt
    46981 tgctataaac tctattattt catcatttat aatagttcca tttgtagtta tatcaaataa
    47041 tatctttttg tcactcaatc tatctactaa atccctatgt atatatttaa tcaaatcaaa
    47101 atttataaat ggttctcctc catgtaaaac aattgttgta taatcactat tactttctaa
    47161 ttctttatta caaataaaat ctattgtttt atcagcagtt tcataactca tattttcttt
    47221 ttttttatca ttaccttcat aacaatatgt acatctcaaa ttgcagtctt cagttacaaa
    47281 tatagtaaat ttcaattaac tttttcatct ccccatacag ctgtatttaa attgtgtttc
    47341 atcatactac accatctatc caattccaat tcattatcct taactgaatc taatatcgct
    47401 gggcaatgcc aacaaaaaat atttacatca caatctttac atttttcaaa gttatatgga
    47461 taaatacttt ctaatttaat caaagacttt agatctcttg ttttattttc ttttataact
    47521 tttacaaatt cattgtcaaa tatatttccc attttatagt catcctttat cagtgaagga
    47581 caaggatata catctccatc ataatttata aatatttgag agtttcctgc attacatgca
    47641 caacatccca tttttttatt ttttttatct ttacacattt ttaattcatt atctaaaata
    47701 tacggaattg taattggaag aactgtatct tcaattaaat agctttcttt attttctagg
    47761 cctcttcctg ttggaataaa atatctttca acaaattctg ttccaagctt tttatttaaa
    47821 tctttaaatt gtttatttaa atgagaattt ttttgtccaa ataccataga cagctttata
    47881 ttactgaatc cattgtcttt tagcagatta acagagctta ttactttatt aaatacacct
    47941 tttcctcgtg tttcactaca agtattttca tctactccat caatactaat atctattttt
    48001 tcaaaattag ttataataaa atcaacatta tgttcatcta ttaaagttcc atttgtggat
    48061 aatattaatt tggtatcagg taatttttgt tttatatatt taattatttc aaaaaaatct
    48121 tctcttatca atggttctcc accagttata attatatgag gagtatttaa aactgatatt
    48181 atatctacga tattttttaa atcatatgta ctaagtaaat ctttcttatt agaagaagat
    48241 tcaacacaac aatgtttaca aaataaattg catctatttg tcaaacaaaa ataaattgca
    48301 acaccattgc ttaacatatc aaagtttaaa ttgttacttt taaaaatttg atttttgttc
    48361 ataatatcta taagattaat aatatatttt ttgtcacttt catcatcaaa ataatttaca
    48421 aaatcataaa tttttatttt attttcttgt cctaaaagaa aatacttata tatttcttca
    48481 gacaatttaa tatattttct aaatttctta ttataaataa ttactagttg attttttcta
    48541 taaataatta aatcttctac attaaaaatc atttcttcag aatctatcac aactaagtcc
    48601 tcctcaaatt agtaaaatat ttttctttaa tatttattac taatatcaac tttactatct
    48661 aattagttat ttaattgttg tttttatgtt cctagttata aagtttatca aatttacatt
    48721 ttattttttt atactatata gaacttttgg tcaataatgt taccatacta aggtcgcatt
    48781 tgcagataaa aataactcta tttttctaaa tttatttaag atatatcatg caaataatat
    48841 aactataaaa cctatcaaca ttttaaattc aaacaaatat aaatcacatt ttttgttcta
    48901 ttattttatt gagtactaaa aaggatgtta tcttattagc atagcattca accattttta
    48961 tcacctccaa atatcctatg ccttaaagat agcatcttct attttatctt tcaatactac
    49021 tgctccaact gggcaattta gagccccaac tagaattagt tcctagttaa tggtatataa
    49081 atagtaattg taaacttgtt tttatctgag tatatttcca catttccatt atatttttct
    49141 actgaacttt ttacactact tattcctatt ccatgtaaaa aggaatcttt cttacttgta
    49201 ataaccttat tattttttaa tacaacttca tttatctttg tattttcaca ttttattaca
    49261 aataacctat ttataacagt tcctcttaat ttaatctttt tttgtatact tgtgtcctta
    49321 atcttaatac aagcttctat tgcattatct attatatttg aaaatatact acatatatct
    49381 ggcatctcta taaaattaca ttctaaaaaa ttaatatcta ctagaaaata tatattattc
    49441 atatcacaaa tagatttttt atcacttaaa ataacatcta gaatcatatt ctgagtatta
    49501 aatatagtat tacattcttt tatttgctta tttatatctt taatatactt atctgcaaac
    49561 tcatttttcc cataaacatt ctgaatacaa atgatatgat tattcatatc atgatatagt
    49621 tttcttattt tcaactgata ttcctgtaaa tttaaataat atttatattg catattcatt
    49681 cttttttttg taatttcata ttctatcttt aaactattat cttttattat tcttcctatt
    49741 atgcttacta atgaaagatt tgatagtaaa aatacagttg atattgtaag tattattaaa
    49801 ctctctttag aatcgataat cttatcttta aaaataaatt caaatattac tattacacca
    49861 ataatgtttg ctattaatgg aatagataaa tatatacaat ccctcttgtt tatttttgtt
    49921 tttaatctga taaacttaag caatggtatt aatactatta gtaatgattt agatatcatt
    49981 attaactcta acttcaacaa attatcctct aataaatcat tcatattttt tatagaatta
    50041 agtgtcatta ctatacttaa tccaatacta tcaaatccaa ttaataacat ccaatatagc
    50101 aaacttataa atacactttt ccatttatcc actacataat ttattttata caatacatat
    50161 gtaataaata tacatataaa taatttaata tttatattaa actcaattgt attcaacata
    50221 gtaattatca taatagcaat tactatgcta ctatttaggg ttaatctatt ctttcttaac
    50281 tcactaaatt catttaataa aaattttaat acaatccatt ctatcgccgt agaaaatata
    50341 ggtaaaaaaa tccaaaatac atttatattt aacataatac atctcccaat acatatgtta
    50401 attttttctt taaattagcc attctatatt tactaactgg tatatcttta ccattaataa
    50461 ctacagtatt tttacatata aattgaatat actccaaatt aattaaatag ctcttgtaac
    50521 atttttaaaa atttattctt tcttaaatca ctgaattcat ttgataaaaa ttttaataca
    50581 attcattcta tcgccgtaga aaatataggt aaaaaaatcc aaaatacatt tatatctaac
    50641 ataatacatc tcccaataca tatgttaatt ttttctttaa atcagccatt ctatatttac
    50701 taactggtac atcttcatca ttaataacca cagtcttttt acatataaat tgaatatact
    50761 ccaaattaat taaatagctc ttatgacatc taaaaaaatt atatttttct agctctaatt
    50821 ctattttatc catactattt ttagtataat aagtatcatt tttagtatgt atagtcaaaa
    50881 cctttttcct aacctctata tacataatac tattaattaa aattttattg attatacctt
    50941 tattttctat cagcataaaa ttttctcttt tttttataat atccgatata caactcaaaa
    51001 tactttcatt taaatctcca aaatctatag gctttaataa atatctataa gcccttacct
    51061 tatagccttc ctgtatgtaa tcaactattg aagttataaa tattatttca gaagtatcat
    51121 tagtttctct aattatttta gccacatcca tgcctgttag ttgaagcatt ttaatatcta
    51181 aaaaaaatat atcaatacct tctaaatttg tttccaataa ttcttctcct gaattaaact
    51241 caaatagttc aatttgacta gaaataccct ctaaggactt taatatacac tctcttaaaa
    51301 aagctatttg tgtaatatca tcctcacaga taactattct atacataaac acccctcctt
    51361 agacattaga tctgaaaaca aataaaatat caatttataa ataattattt agttatacaa
    51421 ctaacatggt catcaaatac tattattcac ttaaaaaatc accccctatt tttagtatgt
    51481 taacaacaaa ataagaagat atcttagatt tttaaaaaca attaatactt aatgtagttt
    51541 tgtatactat ttataggtaa ttttttatat cattttaaac attaaaatta ttgatgttta
    51601 agaactatta tattgatagt aatatataat taatgatatc aaaaattttt aattagactt
    51661 ctctcttatt caagattttt ctatataaaa tctaagaata aatagaaaac taacatctaa
    51721 ccttttattt tttattttcg atctatttac ttgaatttta acataaatct atcttttagt
    51781 atatattaat catgctgaat ttgtgatgac atgtatacaa aatatcgttt agtattttct
    51841 aataaaaaat attactgaaa ttaaaaatct acaatagcat ttaacaagta aaaacatgtt
    51901 tacacaaata tataatttaa ggtctttaaa atagagtatg tattattcta aaaattagtt
    51961 atagttatca cataaaaata gaaaagaatt ttcaaaagat ttaaagaaca tatatacttc
    52021 aattgcagaa gatgtaatgt taagtgaact agcattcttc gaggaaaaat agactcaaaa
    52081 aattagaaaa tagaatcagg ttttagatga tttaagtatt tattttcaaa aaagaaattt
    52141 gattctaagt taataaagaa atatttaaaa aaatcaaaaa attttcttaa ataagtaata
    52201 ggttttgtaa aaatggaaaa atatcaaaat aagactatga tttttaaaac tatagcctta
    52261 tcaataaatt tttatttaaa gaacacacat aaatattttt aaacctaatt tatgtgaagt
    52321 tttatgtatt ttttatataa gtagtattct aatcttactc atctaatata ccaaaaagac
    52381 tgtaagtaag ttcactttta tgcaaactta cccacaatct cttttacaca ttaattctat
    52441 ttattaaaat taaaaatatt tactgctatt ctacccaata aagatgatac tgttgttgtt
    52501 ctggctggta ctgttacttc tatttctcct gtatctgctg ttttaccact tgatgtgtgt
    52561 gtcactgtaa atactaatgt tacttttgtt tctgtatctg gtggcactat tgttccatct
    52621 tt
//
LOCUS       DAMJWC010000021        51657 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMJWC010000021 DAMJWC010000000
VERSION     DAMJWC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.021"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            27..101
                     /locus_tag="PC503_001450"
     tRNA            27..101
                     /locus_tag="PC503_001450"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC503_001451"
     tRNA            116..200
                     /locus_tag="PC503_001451"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC503_001452"
     tRNA            210..293
                     /locus_tag="PC503_001452"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="PC503_001453"
     tRNA            317..391
                     /locus_tag="PC503_001453"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="PC503_001454"
     tRNA            416..492
                     /locus_tag="PC503_001454"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="PC503_001455"
     tRNA            502..577
                     /locus_tag="PC503_001455"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="PC503_001456"
     tRNA            586..661
                     /locus_tag="PC503_001456"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="PC503_001457"
     tRNA            664..752
                     /locus_tag="PC503_001457"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="PC503_001458"
     tRNA            756..831
                     /locus_tag="PC503_001458"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="PC503_001459"
     tRNA            838..911
                     /locus_tag="PC503_001459"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="PC503_001460"
     tRNA            926..1002
                     /locus_tag="PC503_001460"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="PC503_001461"
     tRNA            1020..1096
                     /locus_tag="PC503_001461"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="PC503_001462"
     tRNA            1105..1180
                     /locus_tag="PC503_001462"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="PC503_001463"
     tRNA            1188..1261
                     /locus_tag="PC503_001463"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="PC503_001464"
     tRNA            1269..1345
                     /locus_tag="PC503_001464"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="PC503_001465"
     tRNA            1358..1433
                     /locus_tag="PC503_001465"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="PC503_001466"
     CDS             1509..1922
                     /locus_tag="PC503_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527446.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="PC503_001467"
     CDS             2231..5662
                     /locus_tag="PC503_001467"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF2527447.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTRESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="PC503_001468"
     CDS             5904..7832
                     /locus_tag="PC503_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2527448.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="PC503_001469"
     CDS             8285..8749
                     /locus_tag="PC503_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF2527449.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="PC503_001470"
     CDS             8756..9250
                     /locus_tag="PC503_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF2527450.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="PC503_001471"
     CDS             9266..10291
                     /locus_tag="PC503_001471"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF2527451.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="PC503_001472"
     CDS             10278..12725
                     /locus_tag="PC503_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF2527452.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNKVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="PC503_001473"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="PC503_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF2527453.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSEKLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="PC503_001474"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="PC503_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF2527454.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="PC503_001475"
     CDS             15440..16534
                     /locus_tag="PC503_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF2527455.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="PC503_001476"
     CDS             16663..18840
                     /locus_tag="PC503_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527456.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19020..19871)
                     /locus_tag="PC503_001477"
     CDS             complement(19020..19871)
                     /locus_tag="PC503_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527457.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            20088..21254
                     /locus_tag="PC503_001478"
     CDS             20088..21254
                     /locus_tag="PC503_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF2527458.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFAMIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLVKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="PC503_001479"
     CDS             21276..22922
                     /locus_tag="PC503_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF2527459.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="PC503_001480"
     CDS             23019..24392
                     /locus_tag="PC503_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2527460.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="PC503_001481"
     CDS             24837..25790
                     /locus_tag="PC503_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF2527461.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="PC503_001482"
     CDS             25828..26790
                     /locus_tag="PC503_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF2527462.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="PC503_001483"
     CDS             26815..27801
                     /locus_tag="PC503_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF2527463.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="PC503_001484"
     CDS             27814..28860
                     /locus_tag="PC503_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF2527464.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="PC503_001485"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="PC503_001485"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2527465.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="PC503_001486"
     CDS             31175..34123
                     /locus_tag="PC503_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527466.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="PC503_001487"
     CDS             34101..34565
                     /locus_tag="PC503_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527467.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="PC503_001488"
     CDS             34678..34980
                     /locus_tag="PC503_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527468.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="PC503_001489"
     CDS             35042..36406
                     /locus_tag="PC503_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2527469.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="PC503_001490"
     CDS             36441..36914
                     /locus_tag="PC503_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527470.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="PC503_001491"
     CDS             37086..37736
                     /locus_tag="PC503_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2527471.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="PC503_001492"
     CDS             37910..38842
                     /locus_tag="PC503_001492"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2527472.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="PC503_001493"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="PC503_001493"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF2527473.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="PC503_001494"
     CDS             39826..40311
                     /locus_tag="PC503_001494"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF2527474.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="PC503_001495"
     CDS             40678..42393
                     /locus_tag="PC503_001495"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2527475.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFNRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="PC503_001496"
     CDS             42515..43960
                     /locus_tag="PC503_001496"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2527476.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44398..45879
                     /locus_tag="PC503_001497"
     CDS             44398..45879
                     /locus_tag="PC503_001497"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF2527477.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46100..46255
                     /locus_tag="PC503_001498"
     CDS             46100..46255
                     /locus_tag="PC503_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527478.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46400..47797
                     /locus_tag="PC503_001499"
     CDS             46400..47797
                     /locus_tag="PC503_001499"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF2527479.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47782..48195
                     /locus_tag="PC503_001500"
     CDS             47782..48195
                     /locus_tag="PC503_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF2527480.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEVEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48301..49059
                     /locus_tag="PC503_001501"
     CDS             48301..49059
                     /locus_tag="PC503_001501"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF2527481.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49072..49809
                     /gene="rlmB"
                     /locus_tag="PC503_001502"
     CDS             49072..49809
                     /gene="rlmB"
                     /locus_tag="PC503_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF2527482.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49812..50339
                     /locus_tag="PC503_001503"
     CDS             49812..50339
                     /locus_tag="PC503_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF2527483.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50404..51051
                     /gene="sigH"
                     /locus_tag="PC503_001504"
     CDS             50404..51051
                     /gene="sigH"
                     /locus_tag="PC503_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF2527484.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51125..>51657
                     /locus_tag="PC503_001505"
     CDS             51125..>51657
                     /locus_tag="PC503_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDF2527485.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT        21015 a         5559 c         9796 g        15287 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actgaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttgaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctata aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttca ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaagagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacattag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag acaatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aaaatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatatc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgagttag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agtataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcgttgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaaggagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagagaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gagctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaataaag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatcttattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gagagtaaag aagaagagcg gtttacaaca gatataaatg aattagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaaattat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgagg ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagagccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aagcttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actgtctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tcgccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa atggtctata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggcatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaactcttt tttattataa agataaataa catataactt
    19021 catattttag gtagattttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtat taattaagtc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agttagtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagattaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca atgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatataag gtaatgcgtc cttatatgag ggaggaaaac gttatagtat
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattaggg aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gcttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc tagtcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga agatttattt tatatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacaa
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtga
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatgta caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga agtgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gcttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg cccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ctatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag cactgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactgcaaaa
    28081 gaaactattg tatcgactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagcatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata taagaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 ggtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcatta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaaatttctt aatatttaaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 cataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag aggaaaaata gaaaattatg tagatgggga
    32401 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccactagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggtgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaaaccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta ataatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcctag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcaaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agctacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacca atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggggctact caaagtgtaa tgtggggagt atttgcagca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagactta ataccaggca taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatc taaaaattaa tgatggaaaa cttttcaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
    36901 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaac taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc gccaccaaca tctaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagataaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactgaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcctat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttaatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagac
    41821 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat taaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg ccccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgagaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagatagg gaaggaaatt tagctaatcc ataccataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gttttttgtt ttttatgagt aataaaatgt
    44041 atttgtaact atgtcataag ataagtcata gatacttata ttaaaaagaa tataatagag
    44101 aactattttt aataattaca tattaatgaa agcaaaatat tttgttatat agattttcaa
    44161 taaagcaaac aataaatata aatgaatatt aataaggagt gcttttaatt tttagaaaat
    44221 aaatgactta aaagaaagat ttatgaaatt aaaactagga ttttctgata taataaacat
    44281 gtgtattttt aaataaaaag gatattatta ttagatttga ttaaaaataa acttgcaaaa
    44341 caatgtacta gtttaatatt atagttatat tgaataaaat atcaggagga agtaaaaatg
    44401 aatgtaagag taaggtttgc accaagtcca acaggatttg tacatatagg tagtttgaga
    44461 actgctttat ataactattt atttgcaaaa aaaatgggcg gagaatatat attaagagtg
    44521 gaagatacag accaaagtag attagtagaa ggtgctatag agaatatgct taatgctatg
    44581 aaatgggctg gggtcaacca tagtgaaggt gttatattag atgatagtgg aaaagtagta
    44641 caaaaaggag aatatggtcc atatattcaa tctcaaagat tagatatata ccaagaatat
    44701 ataaagcaac ttttagatag tggaaaagct tattactgtt tctgtacaaa agaaagactg
    44761 gatgaagtaa gagatgctca aagagcagca ggagaaacag ctaaatatga tggtcattgt
    44821 aagaatcttt ctaaagaaga agtagaagcg aatataaaag caggaatacc atatgttata
    44881 agattaagat tgccagagaa tcatacaatt aagtttacag acttagttag aggagatatg
    44941 gaatttaata ctaatgactt agatgaccaa gtattaatga aaacagatgg atttccaact
    45001 tatcattttg cagtagttgt tgatgactat ttgatgaaaa ttacacatgt tataagagga
    45061 gaagaatggg tatcatctac tccaaaacat gtttatttat atgaagcttt tggatgggaa
    45121 gcacctgtat ttgtgcattt accaaatata cttaataaag aaaagaaaaa attaagtaaa
    45181 agacaaggtg atgtagctgt tgaagacttt aagaaaaaag gatatttacc agagggatta
    45241 gtaaactatg tagcattagt tggttggtct cctgaagata atcaagaatt gtttacaatg
    45301 gaggaattag aaaaagcctt ctctgtagaa agagtatcta aaagtggtgg agtatttgat
    45361 actgaaaaat taaattgggt taatcagcac tatataaaag atggtgatga tgcttatcta
    45421 acagacttag caataccatt tttaatagaa gatggattta taacagaaga agaagctact
    45481 aataaatatg atttcttaaa gagtatgata tcagtactta aagagaaatt acaatatgta
    45541 aaagaagtta ctgaacatgc aagtatattt tttggagata aaatagaggt agaaactgaa
    45601 gagggaagag agttcttaag attagaacat atacctactt taatagatgc tttgagagaa
    45661 aaaatagaaa aaacagaggt attaaatgct gagtttgttc aagctatgct taaagaaata
    45721 caaaaagagt acaaaataaa agggaaaaat ttatttatgg gctcaagaat aattttgaca
    45781 gggcaaatgc atggtccaga tttaccaaaa gtaatggaag ttttaggaaa agaaacttgc
    45841 ttaaatagaa tagcttatgt aaaaaataat atattatagt cataaaagtc cgctaattta
    45901 gaagcggact ttttttgtgt tagtatttgg tgaaaatatc tgcttaagaa aatgaaggta
    45961 tttaaggtaa taaatttaat atataaaaag caaagcaaaa atataaataa aatatgaata
    46021 ataaactaat aaaatattaa gcatagaaga agggaatcta ttattttagt ttgatttaat
    46081 tattaagggg gtaattacta tgtatagtaa tattgatgat gttaaaaagg aattaaagga
    46141 gctatgctta gaatatgtta caattttaga aaaattaaaa gatgaaaaaa tgattacaga
    46201 agaaactttt gaaaagtgct cttctcaaaa aaaaatattt ttagaagaac aatagaggat
    46261 ggtaatagta ttattattat gtagtttgaa agatagtacg aaaaatgata gtaatactat
    46321 tatttattgc aattttcaac tataatataa tatataatgt taagaagata atttataaaa
    46381 atacagtgag gtgatgagtg tgaaagttta taatacattg actagaacaa aagaagaatt
    46441 tgttccatta gaagaaggaa aggtaaaaat gtatgtgtgt ggtccaacag tttataacta
    46501 tatacacata ggtaatgcaa gaccatttat aatatttgat actctaagaa ggtatttaga
    46561 gtatagagga tatgatgtaa cttatgtaca aaactttaca gatgttgatg ataagattat
    46621 aaatagaagt catgaggagg gaatatctcc tgaagaagtt gcggctaagt atataaaaga
    46681 atattttgta gactgtgatg ggctaggaat aaaaagagct actgttcatc ctcaggttac
    46741 agataatata caacagatta tagagtttat aaaagagttg gaagataagg gatatgcata
    46801 tgcagtaaat ggtgatgtat attttgatac aaataagttt gaaggttatg gaaaactttc
    46861 aggtcaaaaa caagaagatt tagaggcagg ggctagaatt gaggttaatg accaaaaaag
    46921 acatcctatg gactttgttc tttggaaggc aaaaaaagaa ggtgagccag gatgggatag
    46981 cccttgggga gaaggtagac caggatggca tatagaatgt tctgttatgt ctaagagata
    47041 tttaggtgaa acaattgata tacatgcagg tgggcaagat ttaacattcc cacatcatga
    47101 aaatgaaata gctcaaagtg aagctagaag tggaaaaaca ttctcaaaat actggatgca
    47161 taatggatat ataaatataa atgatgaaaa gatgagtaaa tcaaaaggta atttctttac
    47221 agtaagagat atatcaaaat tatatgattt agagatagta agatttttca tgttatcagc
    47281 acattataga aatccagtaa actttagtga tgagatgtta aatcaagcta aagcaggtct
    47341 tgaaagacta tataatacta aagaaaaatt agaatttacg ctaagtaatt tagtagaatc
    47401 tcctttaaca gaaaaagaag tagagcttgt taaagaatta gatgacttta gacaaaaatt
    47461 catagatgct atggatgatg atgttaatac agcagacgca gtaagtgtaa tatttgaatt
    47521 agctaagtta ataaattcta atgtagatga aaattcttct ttggagtttg ctaaaaaatg
    47581 cttagatgaa tttaatgaac ttacaggagt attaaatatt gtaaataaga aaaaggatac
    47641 tgtattagat aaagacattg aagaattgat acaaaaaaga actgatgcaa agaaaaataa
    47701 agagtttcaa ttagctgatg atattagaca acaattacta gatatgggaa ttgtattaga
    47761 agacacaaga caaggtgtta agtggaaaag gatataaaaa tggaaaaaac tgaattagtt
    47821 actatgtcac cattagtttt agcatactta ggtgatacag tgtatgagac atatataaga
    47881 gaatatttaa ttagacagaa tacacaaaga aaagttaatg atttgcataa actagctata
    47941 aagtatgtaa aagctaaagc tcaggcaact ataattcatg aagttgaaat tgagttaact
    48001 gaagaagaga gtaaaattta taaaagggga agaaatcaaa agtcaaatac ttctcctaag
    48061 aatgcagata ttatagacta caaacatgca actgggtttg aggcattagt tggatatttg
    48121 tatttaaata atgaaataga gagacttcaa tatattatca ataaaggaat caaaattatt
    48181 gaaagagata tgtaaatatt aaagagtgtt gtcttaataa taagtaataa ggcaacactt
    48241 tttttataac taatgtataa taaatatata gaaattagta atgagaaagg ataaaaagtt
    48301 atgaaagtaa aattaatatc acatacacct gaaccagaaa aagtaatagc tatggcagct
    48361 aagctatgtt attcaccagt tgggacagac gaaatagaaa aagacttaac agatgaaagt
    48421 atagagaaat ttttaaatat gttattaagt ataggtcatg ggtcaatatt agaacatgct
    48481 tcatttacat tttcaataga aggtatttca agggcatgtt cacatcaaat tgttagacat
    48541 cgtatagcta gtttttcaca acaaagtcaa agatatgtta aattagaaca atttgagtac
    48601 ataattcctc cagaaataga aaaaatagaa aaggcaaaag agttatttat agactccatg
    48661 aaaaaagacc aagagaatta tgataagtta gttgaaatat tgtttgaaaa tcattataat
    48721 gacctaataa aaaacggtaa aaatgagaaa acagctaaaa gacaagctga gaagaaagca
    48781 atagaagatg ctagatacgt atttccaaat gcatgtgaaa caaagatggt atttactata
    48841 aatgctagaa gtttgtttaa tttctttgaa catagatgct gtgaaagagc acagtgggaa
    48901 ataagaaatt tagctgtgga gatgttaaga gaggttaaaa aggttgctcc tatattattt
    48961 aaaaagactg gtccaagttg tgtaaatgga agttgtccag aaggaactat gacttgtgga
    49021 gatatagttc aagttagaga aaaatttaag gccttgtagg aggtgaataa tttggcgagt
    49081 atagaaggaa gaaatccggt aatagaagca ataaaaagcg acagagaaat agataaaata
    49141 ttaattgcaa attcagctaa agaaggttca attaagaaaa taataggaat ggctaaagat
    49201 aagaatataa ttattcagta tgttgataaa cataagttag atgaagtaag tacaagtcat
    49261 tcacatcaag gtgtaatagc ttatgcaagt gagtataagt attatgaatt agatgagcta
    49321 atagatttag caaagaataa agatgaagac ccatttttca ttatattaga tgagataaca
    49381 gacccacata atttgggttc aataataagg acagcagatg cagtaggagc acatggagtt
    49441 atcattccaa aaagaaggtc tgtacacata actcctgtag ttgccaaagc atctgctgga
    49501 gcagtagaat atatgccagt ttgcaaggta accaatatag ttaatacaat aaaaagactc
    49561 aaagaagaag ggctgtggat tgctgcagct gatatggatg gagaaacttt ttataaacaa
    49621 aatcttactg gtcctcttgg tgtagtaatt ggaagtgaag gttttggaat atctagattg
    49681 gttaaacaaa actgtgactt tatagtaaaa atgccaatga taggtaatgt tacatcttta
    49741 aatgcatctg tagcaggtgg aatactttta tatgagatat tcagacaaag actggataaa
    49801 agtaaatagg catgaaaaaa aatataaatc attacttaat aatagatggc tacaatatta
    49861 taaatgcgtg ggacaatttg aaagaactgg ctaaagagga cttagaagat tctcgagaaa
    49921 agcttattga tgacattata gaattttctg agtttatggg ttataagact ataatagttt
    49981 ttgatgctta taatgttaaa aattctcgag aaaaagttga aaaaagaaaa cacataacaa
    50041 tagtttatac aagagaacac caaacagcag atagttatat agagaaattt ataacttctt
    50101 tatcaaagta tgatgatgta aaagtagcca ctaatgacta tgcagaacag caaatgattt
    50161 taggaaaagg tgctactaga atgtctgcaa gagaattaaa gttagagtta gatcgttcca
    50221 agaataaaat gaaggaaaaa aatatcggtt tgaggaaaaa aattcagcga aattggttgg
    50281 aggaaaggtt agataaagaa acattgtcga aacttgagaa cattcgtaga aagcgttgaa
    50341 attactaggt tctttagact ataatatacc tataaatttg ttttatatat gggggagatt
    50401 tacatgttgg tagcaaaaga aaaaagttat gagttagtgg acaattgtca gcaggatgag
    50461 tataacattg tattaagagc aagtgaaggg gataaaatag cactagagta cattattact
    50521 aaatacagaa attttgtaaa ggcaaaagca aagtcatatt ttttaattgg agcagataaa
    50581 gaagatataa tacaagaagg aatgataggc ctttataagg cagttagaga ttttgatgga
    50641 agtaagacca attcatttaa atgttttgcg gagatatgta taacaagaca aataataact
    50701 gctataaaaa ctgcaacaag acaaaaacat atacctttaa attcatatgt ttctttgaat
    50761 aaaccaatat atgatgaaga gtcagacaga acacttttag atattatagc tacaagtata
    50821 gtaacagatc cagaagagct tataattagt aaagaagagt taaaaaatat agaatcaaaa
    50881 atgaacgaat tgttaagtga cttggaatta gaagtactag aattatattt aaatggaaag
    50941 tcataccagt ttatagcgga caagcttaaa agagatgtaa agtcaataga taacgcttta
    51001 caaagggtta agagaaaatt agaaaaacat cttgaaaaca gaaatgatta atagtaaaat
    51061 acttaccata agcttattgt gagcaaaatt aatttatatc gaaagataag ggaggaaatt
    51121 caaaatggct aaagctaaat acgaaagaac aaaacctcat gttaatatag ggacaatagg
    51181 acacgtagac cacggtaaaa ctacattaac agcagcaata acaaaaacat tatatgacag
    51241 atatcaatta ggagaagcag tagatttcgc aaacatagat aaagctccag aagaaagaga
    51301 aagaggaatc acaatatcaa cagcacacgt tgagtatgaa acaccaaata gacactatgc
    51361 acacgttgac tgcccaggac atgctgacta cgttaagaac atgataacag gagcagcaca
    51421 aatggacgga gcaatattag tttgttcagc aacagatgga ccaatgccac aaacaagaga
    51481 gcatatacta ttatcaagac aagttggagt accatatata gtagtattct taaacaaatg
    51541 tgacatggta gatgatgaag agttattaga gttagtagag atggaagtaa gagatttatt
    51601 aacagaatat gatttcccag gagatgacac tccaatagta agaggttcag cattaat
//
LOCUS       DAMJWC010000022        48266 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMJWC010000022 DAMJWC010000000
VERSION     DAMJWC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48266
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.022"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(220..1581)
                     /gene="rlmD"
                     /locus_tag="PC503_001506"
     CDS             complement(220..1581)
                     /gene="rlmD"
                     /locus_tag="PC503_001506"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2527486.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVLL
                     RRK"
     gene            complement(1608..2330)
                     /locus_tag="PC503_001507"
     CDS             complement(1608..2330)
                     /locus_tag="PC503_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2527487.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(2330..2659)
                     /locus_tag="PC503_001508"
     CDS             complement(2330..2659)
                     /locus_tag="PC503_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF2527488.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            2989..3915
                     /gene="fba"
                     /locus_tag="PC503_001509"
     CDS             2989..3915
                     /gene="fba"
                     /locus_tag="PC503_001509"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF2527489.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(4050..5681)
                     /locus_tag="PC503_001510"
     CDS             complement(4050..5681)
                     /locus_tag="PC503_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527490.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(6164..7201)
                     /locus_tag="PC503_001511"
     CDS             complement(6164..7201)
                     /locus_tag="PC503_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2527491.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(7220..8005)
                     /locus_tag="PC503_001512"
     CDS             complement(7220..8005)
                     /locus_tag="PC503_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2527492.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(8038..9171)
                     /locus_tag="PC503_001513"
     CDS             complement(8038..9171)
                     /locus_tag="PC503_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2527493.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(9219..10346)
                     /gene="hadC"
                     /locus_tag="PC503_001514"
     CDS             complement(9219..10346)
                     /gene="hadC"
                     /locus_tag="PC503_001514"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF2527494.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(10346..11572)
                     /gene="hadB"
                     /locus_tag="PC503_001515"
     CDS             complement(10346..11572)
                     /gene="hadB"
                     /locus_tag="PC503_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF2527495.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(11587..12387)
                     /gene="hadI"
                     /locus_tag="PC503_001516"
     CDS             complement(11587..12387)
                     /gene="hadI"
                     /locus_tag="PC503_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF2527496.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(12426..13625)
                     /gene="hadA"
                     /locus_tag="PC503_001517"
     CDS             complement(12426..13625)
                     /gene="hadA"
                     /locus_tag="PC503_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF2527497.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            14302..15300
                     /locus_tag="PC503_001518"
     CDS             14302..15300
                     /locus_tag="PC503_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF2527498.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            15662..16189
                     /locus_tag="PC503_001519"
     CDS             15662..16189
                     /locus_tag="PC503_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF2527499.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            16216..16812
                     /locus_tag="PC503_001520"
     CDS             16216..16812
                     /locus_tag="PC503_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF2527500.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEIAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(16877..18460)
                     /gene="asnB"
                     /locus_tag="PC503_001521"
     CDS             complement(16877..18460)
                     /gene="asnB"
                     /locus_tag="PC503_001521"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2527501.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDRYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(19026..19862)
                     /locus_tag="PC503_001522"
     CDS             complement(19026..19862)
                     /locus_tag="PC503_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2527502.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(19886..21352)
                     /locus_tag="PC503_001523"
     CDS             complement(19886..21352)
                     /locus_tag="PC503_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2527503.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASAIATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(21355..23217)
                     /locus_tag="PC503_001524"
     CDS             complement(21355..23217)
                     /locus_tag="PC503_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2527504.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(23464..24327)
                     /locus_tag="PC503_001525"
     CDS             complement(23464..24327)
                     /locus_tag="PC503_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2527505.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(24382..25314)
                     /locus_tag="PC503_001526"
     CDS             complement(24382..25314)
                     /locus_tag="PC503_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF2527506.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNQKDLPIW"
     gene            complement(25400..25951)
                     /locus_tag="PC503_001527"
     CDS             complement(25400..25951)
                     /locus_tag="PC503_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527507.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(26180..26671)
                     /locus_tag="PC503_001528"
     CDS             complement(26180..26671)
                     /locus_tag="PC503_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527508.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(26699..27259)
                     /locus_tag="PC503_001529"
     CDS             complement(26699..27259)
                     /locus_tag="PC503_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2527509.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(27411..28568)
                     /locus_tag="PC503_001530"
     CDS             complement(27411..28568)
                     /locus_tag="PC503_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2527510.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(28605..29546)
                     /locus_tag="PC503_001531"
     CDS             complement(28605..29546)
                     /locus_tag="PC503_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527511.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(29633..30325)
                     /locus_tag="PC503_001532"
     CDS             complement(29633..30325)
                     /locus_tag="PC503_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2527512.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(30434..31246)
                     /locus_tag="PC503_001533"
     CDS             complement(30434..31246)
                     /locus_tag="PC503_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF2527513.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(31297..32208)
                     /locus_tag="PC503_001534"
     CDS             complement(31297..32208)
                     /locus_tag="PC503_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527514.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(32267..32998)
                     /locus_tag="PC503_001535"
     CDS             complement(32267..32998)
                     /locus_tag="PC503_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF2527515.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            33087..33338
                     /locus_tag="PC503_001536"
     CDS             33087..33338
                     /locus_tag="PC503_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527516.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            33572..33991
                     /locus_tag="PC503_001537"
     CDS             33572..33991
                     /locus_tag="PC503_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527517.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            34016..39073
                     /locus_tag="PC503_001538"
     CDS             34016..39073
                     /locus_tag="PC503_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF2527518.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(39258..39995)
                     /locus_tag="PC503_001539"
     CDS             complement(39258..39995)
                     /locus_tag="PC503_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527519.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(40014..40949)
                     /locus_tag="PC503_001540"
     CDS             complement(40014..40949)
                     /locus_tag="PC503_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2527520.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            41157..43733
                     /locus_tag="PC503_001541"
     CDS             41157..43733
                     /locus_tag="PC503_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2527521.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            43745..44416
                     /locus_tag="PC503_001542"
     CDS             43745..44416
                     /locus_tag="PC503_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527522.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            44443..44784
                     /locus_tag="PC503_001543"
     CDS             44443..44784
                     /locus_tag="PC503_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527523.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(45144..47786)
                     /gene="adhE"
                     /locus_tag="PC503_001544"
                     /gene_synonym="adhC"
     CDS             complement(45144..47786)
                     /gene="adhE"
                     /locus_tag="PC503_001544"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2527524.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        16194 a         8124 c         5812 g        18136 t
ORIGIN      
        1 tagattaaat atattttcac ataaaaaata gatattaaat ttataaattt aatatctatt
       61 tctataatta aaactttttt tatttcgtat tcccacactc catatatata actacagaca
      121 catcaaaaca ccttttcaat tctttattcc taattttatt accctctaat ctaaatatta
      181 tatgtctatg aaactgtcta aagctcaaga tttctagcat tattttcgac gtagcaacac
      241 tacagtctca caatgtggcg tatttgggaa catatccata cacttaacca tcttaatctc
      301 ataaccatac cccttaaaat caaccaaatc aacaaccaaa gacttaggat tacaagaaat
      361 ataaacaatc tccttagcac caaatccaca aatatcccta atagcatcct tatgaatgcc
      421 tggtctagga gggtcaacaa taatcaaatc aggcttgtcc tttaaatcct taacaacctt
      481 agccacatcc ccagcaataa actcacaatt agtaagtcca ttcaacttag cattctcatt
      541 agcagcaaca acagcttcct caactatctc aataccatac actttcttag cagcaccagc
      601 cataacctgt ccaatagacc cagtaccact atacaagtca aatacaactt tatcattgta
      661 atctccaata aaatccctag caatactata aagaacctct gctcccttag tattggtttg
      721 gaaaaacgaa aatggtgaaa tcttaaactt aagacctaaa atttcttctt gtatataatc
      781 tcttccatac aatactctta actcatcaca ttggactgca tctgctaaac catcattaat
      841 agtatgaagt acacctacta actcagcttt taaatcaatc cctaaaagca tatctttaaa
      901 ctcatacata tcaaaatctt cttgagaaga agttactata ttaaccataa tctcattagt
      961 atgaatccct tttctaacta caagatgtct caaatatcct ttgtgattca ttgttctata
     1021 ataaggaagc tttttttcat tgaaaaactc tacactagaa actaatatct ttgagaagtc
     1081 ttcatcaacc aacatacact cctcaacagt ttgtatatct atatgctttc cttttttatg
     1141 aagacctaat gtcaaaggtc cattttttac ttcatctcca aaagtatatt ccatcttatt
     1201 tctataatat ttgttttctg gacttccttc tatccctaaa aactgaaatc caaataaatc
     1261 ttgctttaaa aataaatcca taacttgttt ttcttttatt tctaattgtt tttcatatgg
     1321 cacagacaat agtgtacatc ctccacactc tctaaagtgc ttgcaagttt cttcagtttc
     1381 aagtggtgag ttctctaata attctatcat cttaacttca gctttcttac ttctaacttt
     1441 tttaactcca gctctcacct tttgaccact tattccaccc ttcatatgga taactctatc
     1501 tccaacttgg cttaaagatg taccaccaaa ttccatttta tctacttcaa attctataac
     1561 atcttttttc ttcacagaca ttcctccaat ttactatagt atctttatta tctttcttca
     1621 atcaatttta cttcttcatc tgttaactct ctatactcac ctaactctaa actttcatcc
     1681 aattttaaat tgcccataga caatcttttt aagtatacta cttttttgcc tacgctttca
     1741 aacattcttt ttacttggtg aaacttacct tcatgtattg taagctctat ttctgattca
     1801 tcatcacttt ttaatatatt taactgtgat ggcatagttt tatatccgtc atcaagcact
     1861 acaccttcta aaaaagcttc tacatcttct tcagtaacta ctccatcaat ttttgcataa
     1921 taagtcttag gcacatgctt cttaggagat aaaactctat gagaaagctt tccatcatta
     1981 gttaaaacta ataatccctc tgtgtcttta tctaaccttc caacaggaaa tggttcaaaa
     2041 gctaagtatg ataaatcaat taaatctaat actgttgggt catatttatc tgtagttgct
     2101 gatatatatc catcaggttt attcatcatc aaatatatat attctctata tataacttct
     2161 tctccattaa ataatatctc atcattttca gtgtctactt gagttcctgg atttgaaact
     2221 tcacttccat ttactactac agacccttgt ttacaatact tctttatttc acttctactt
     2281 ccataaccta aatttgaaag aattttatct atacgttgct ttttagccat taaaaatgct
     2341 ctccattctc ataatatttt tctttttcaa atactgtaaa tgctaaatct atactttcta
     2401 catctaaatt atttcttata ctatcagtta ttattcttgc tactatatct tgtacttctt
     2461 gtcctctatc aaaccaagct acttcaacaa aaggatatac atctgctatt ttaccatctc
     2521 ttattgcaac tgactttata cattctattt caaagtagtc tcttggacat tttacagctt
     2581 caactaaatc atttatcatt ttttcactta ttttacatat atcattttca ttaattcctc
     2641 ttatttttat ctgtggcata gtttatctcc tttattttaa atttttagtg aattatcatc
     2701 cacttaattc ctttcgataa cgtttgaagt ggtaacttct tggtcaaggc aactattgtt
     2761 atcagtatct ccaaactaat aaggtagttc ctacccttat agttagcatt atatagctag
     2821 ttttcctaaa ttgtttatat tctttattat tttatttaat cctattgtct tctatttaac
     2881 attatacttg taatttatag ttattacaat ttactatata ctttttttga tttaacgtta
     2941 taatataagt gatgggtaaa ttttaaaagt taataggagg agtttaaaat ggcattaatt
     3001 actacaaaag aaatgtttaa aaaagcttac gaaggtggat ttgctatagg tgcatttaac
     3061 ataagtgact tagaacaatt acaaggtgtt ttaaaagctg ctaaagctaa aaattcttat
     3121 gttatgatac aagcttctat gtcagctgtt aaatatgctg gacctcatac attagttgaa
     3181 atggttaagg ctgcttctga tgaaataggt gtagatgtag ctcttcactt agaccatggt
     3241 ccaaatatgg atgctattaa aacttgtatt gatgctggtt tctcttcagt tatgatagat
     3301 ggttctcatt ttgactttga agaaaatgtt agaataacta aagaagctgt tgaatatgca
     3361 cactctaaag gtgttgttgt tgaagcagaa cttggtgttc tagctggaac agaagatgat
     3421 gttacttctg atgttcacaa gtatactcaa ccagctgagg cagttgagtt cgttgaaaga
     3481 acaggtgttg attcattagc aatagctatt ggaacttctc atggtgcttt caaattcaaa
     3541 ggagaagcta aattaagatt cgatatacta gaagaaatcc aaagcaaatt accaggtttc
     3601 ccaatagttc ttcatggtgc atctgctgtt gaccaaaacg ctgttgctac atgtaatgaa
     3661 tttggtggaa atatagctgg tgctaaaggt gtacctgtag atatgttaag aaaagcatct
     3721 tctatggctg tttgtaaaat aaacatggat actgacttaa gactagctat gactgctgct
     3781 atcagaaaat tcttagctga aaatccaaaa gaatttgacc caagaaaata cattggtgct
     3841 ggtagagatg ctatacaagc tgtagttgaa agcaagatag atgatgtttt aggttctgct
     3901 aactctataa actaatataa cttttaaata tttataaaag aaaagagatg acttaaagta
     3961 attaaattta tttttaagcc atctctttta agttgtataa attatgtatc ttataatatt
     4021 ttaattatat tgtcttttta aactgacagc taaacgtgaa tatgtccact ctttatcttt
     4081 ctatggatgg tagaaggata tatacctata acttcagcag cctttgttat tgaaccatac
     4141 ttatttatag ccttacttat cattatttgg tccactattt tatatgcatc attaagattc
     4201 ataattccat ttaccactat tggtgataaa tcatctgttt cattatcaat catatctaaa
     4261 tttatcagca tgttaaattc atcttctcca attacatttt tagctgataa tactacaaat
     4321 ctttcaatga tgttttttaa ttctcttatg tttcctggcc aagaatattc ttctaataac
     4381 tcaataactt taggcgaaac ttctacttct ctattgtact tttcattgta aagttttaag
     4441 aaataattta ctaatggtac tatatcctct tttctttctc taagaggagg tatttttact
     4501 ggaataacac ttaatctata gtacaaatct tgtctaaatt taaggttatt tctaaggtct
     4561 tcatgagaaa tattagtagc acttatatat ctaacatcta tttttatagg cttactacca
     4621 cctattctag taatagtatt ttcttgtata accctaagta attttttttg catctgcatt
     4681 ggtaactcac ctatctcatc caagaaaata gttccaccat tcgcctcttc aaaaagtccc
     4741 tttttacctt ttttcttagc tccagtaaaa gaaccttctt catatccaaa aaactctgac
     4801 tctaataatt catttggtat agctccacag tttatagcta taaaaggttt gtctctcctt
     4861 gaactatact tatatattgt tcttgctatt atttcttttc ctacacctga ttctccattt
     4921 ataaatatag aagaatctga ggctgcagct ctcttaacaa ctttttttat attgtccata
     4981 atcttacttt gacttatata ctctgtgtct tctgatatat cactatattt tatctgagat
     5041 tcaagcttaa taacccttga aatatctctc cctgttagta ctcctcctgt aagctttccc
     5101 ttagaatccc atcttggaac tgccgtatat gcaataagct tcccatctgg gtaaacgata
     5161 tttctataaa tctttttctt cactttaagc atgtttaata ttattggttc ttcaactaat
     5221 ccttgtctca caaggtctgt tatatttcta ccaagtacct cagttctttt aaaaggtaat
     5281 atctcatcac tgacagtgtt catcttttca attaccccat ctttgttaaa cacaacaaca
     5341 acttcatcta tatgctctat tatatcttca attactttat cagatattag agacttctca
     5401 aataaataaa ctatattatt ttcattatta ttatctttca tattgtatat atgtgcagtc
     5461 atccttaact ctctgaaagc tattttcttt ttactatctg tcagtatttc tgttttgtca
     5521 aaatttgaat ctaattcatt tatatttcta ggctttttta tatctagaaa actaaaaata
     5581 ctatctatta gatgattaca gtatattatt tcgcctgatt ctttacataa aatggctgga
     5641 ttttctacat gttctataag ccctattaaa ttattatcca ttaatattcg cacctttcat
     5701 taagtaattt attgaactac atacaaaatt tattgtttgc ttacaataaa taccatcagc
     5761 acatataatc aactccttat aatattcgtc ttttcaagta gtttatttca ttaaaacgta
     5821 actaagatat aattttaatg attatagttt gttaaaaatt tcattttgct tttaattgta
     5881 ttttatcaca tatttagtaa ttatttgtct atttaataca atttaattaa atttaagatt
     5941 tatttaaaaa aacaaagata atccttacag aatataactc acaatttgta agcaatatac
     6001 atataaggat tatccagatt atcttgtatt ataaaatttt attcaaacag actttttaat
     6061 aactgacaaa tacacactag caataactta tcaaagggtt aataattatg ttactaacta
     6121 ataagactta ttcaatcagt aatatttata tagtttgtat ctattaagct tttatagctt
     6181 ctaataaatc atcaacgcta tctaattttt ctataagcat tggaactatt tcatgtaagt
     6241 ctccaactac tccatagtca gcgatttcta aaattggagc tgctgggttt ttgtttatag
     6301 caattatgaa atctgatgat tgcatacctg ctaaatgttg tattgctcct gatataccac
     6361 aagctatata taggtttggt ttaacagtag ttcctgtttg acctacttgg tgagaatggt
     6421 ctatccatcc agcatcaaca gccgcacgag aagaaccaac tactccacct aatttgtcag
     6481 ctaatttctt aagcatttca aatccttctg gtccacctaa tcctagacca cctgatacta
     6541 taacatttgc atctgtaaga gatactaaat ctttcttagt tttaactgtt tctaaaacag
     6601 tagttcttat atcatcttga gttattttgt agtctaatgc tataacttca ccagttcttg
     6661 tttcgtcttt ttcagcttta tccataacac caggtctaac tgtagacatt tgaggtctat
     6721 ggtttggaca aatgattgta gccattatgt ttccaccaaa tgctggacga gtttgtttta
     6781 ttttcttatc ttctgggtct atttctaact tagtacagtc agctgttaat ccagttccaa
     6841 ctcttgaagc tattctaggt gctaagtctc tacctatatg agttgctccg aaaagcatta
     6901 tttctggttt tatttcatct attgcatctt ttattacttt tgtatatgca tcagttgtat
     6961 atttttctaa aagagcatca tctgcaacat aaactttgtc agctccaaaa gtgattaatt
     7021 ctttagctaa tccatcaaca tcttttccta ataatattgc acaaagttct gcatctactt
     7081 ctttagctaa ttttcttcct tctcctaata attctataac tactggagct atttttcctt
     7141 ctctttgttc tgcaaatatc catacgtttt tataagaact taaatctttt atatcattca
     7201 tagtttgtac tcctccaact tatataatgt gcttttgttt tagaccgatt attattttac
     7261 tagctatttc atcagcttta ccttctaaga tttctccttt tcctcttggt tcaggagtaa
     7321 atgatctaaa tactttagtt ggtgatgctt ttaaaccaac ttcttcttta tttacatcta
     7381 aatcatcaat tgtccaaact tttacatcat gtttatatgc ttttactatt ttatcaacag
     7441 acatgtatct aggtgtattt aactctttta ctgctgttaa aagtacaggt gtacttactt
     7501 ttattaattc gtatccatct tctaattgtc tttgaactat tatatctttt ccttctattt
     7561 tgaaatcttg tacatatgta acttgaggaa tgtctaattt ctctgcaatt tgtggtccaa
     7621 cttgtgcagt atctccatct attgcttgtc ttcctgcaaa tattatgtca tagtcaccta
     7681 ctttagatat tcccgctgca atagtatttg atgtagccca agtatcagct cctccaaatg
     7741 ctctatcact taataatatt gcatcatcag cacccatagc taaacactct cttagcataa
     7801 agtctgcttg aggaggtccc attgttataa ctgttatagt tacatcatca tgctcatctt
     7861 taatttttaa agcttcctct aatgcatttg catcatctgg gtttaatata cttggaactc
     7921 catctcttat aagagtacct gtttctttat ttattcttac ttcgttagta tctggaactt
     7981 gttttacgca aactaatatt ttcaaagtct atacctccaa tttcattaga ttatttatta
     8041 ttttaatacg tttgatgaaa ttaccatttt ttgaacttct gatgttcctt cgtatattga
     8101 tacgattcta gcatctctgt acattctttc gatttcataa tcttttataa atccatatcc
     8161 accgtgaagt tgtaatgctt tataagcaac ttcatttgca atttctgatg catagtattt
     8221 agccatagca gattcttgag caactctcat tcctgcatct ctcttttgtg ctgcatcata
     8281 aactaatcct ctagctgcac aaacttttgt ttccatgtca gctatagtaa attgagtatt
     8341 ttggaattta gctataggct taccaaattg aactctttgt tttgtatatt taacagcttc
     8401 atctaaagca ccttgagcta ttcctagagc taaggcagca acacctattc taccaacttc
     8461 tagagtaccc attgctatct taaatccttg accttctttt ccaagtaagt tttcttttgg
     8521 aactttaacg ttttcaaata ttaagtcaga agtttcagtt cctcttatac ccatcttatc
     8581 ttcatgagct cctgttgaga aaccatccca tttactttct actataaacg ctgatgttcc
     8641 tctaagtcct ttacttctat ctgtaactgc tattactata gctacatcac agaatggtcc
     8701 attagttatg aaagtttttc taccatttaa tatatagtgg tctccaacta attctgctgt
     8761 tgtttgttgt ccacctgcat cagaaccagc tcctggctca gttaaaccaa atgctcctat
     8821 taattcacct gttgctatac cttttaagta tttttgtttt tgctcttcag taccattgta
     8881 aagtattggt aatgaagcaa gagaagaacc agctgtaaca aaagtagctg ttgaagcaca
     8941 tcttctagct atttcttcca ttactatagc gtaagaaaca tatcctgctc ccccaccacc
     9001 atattcttct gggatattac tgcttataaa ttttgcatca gctaattttt tgattaattc
     9061 cttaggcatt acacctgttt tatccatttc tgctggtaaa gtatctaatt ctttactaac
     9121 aaaatctctt actgcttttc ttaaaagttc ttgttctttg ttatataaca tagcttcctc
     9181 caattttcat attttatagt aaatttattt taatgaactt acgctaaact catcatctca
     9241 gcaaaagttt gaatacgagt tctggcttgt tcattattct gagtttgttg gtcgatttca
     9301 acatataaag taggtattcc actatcttct atatcttttc taactaaagg ataatcgtat
     9361 tcttctgggt cacagaattt catcatacag aagataacac catctatatc tttcttttta
     9421 acttcatcta ctataagtga cccacgtttt ttcttagggt cataagctaa tgaacatcct
     9481 tctatgtttg accattgtct tgctaatctt tctaacgcat catcacctgc tggtacatct
     9541 gttctgaatt gtcttgtttc ttgtgctaag tcgtcagcta caactgatat attgttgtct
     9601 tctaaaatgt ctaatatatc tttagaatca gctaatatac ctgttaataa aactttcttt
     9661 ccagaacaga cttcttctgg catagcattt aattttgcta ttaaatcttt cactagctca
     9721 gtatgttctt cttttctcat aaagaaccca ctcttaatta ctaagcttct tattgatggt
     9781 tttatagtat tagaatgttt ataagctact tcaacaaagt ctctcatagt ttttctatgt
     9841 tcattgtaaa cttctatact ttcatgaatt tttgcttctt ctatttcata tccacaaatt
     9901 tcttcaagtt ctctttttac gcctttgtac tcactgatta agtattttac accagcttca
     9961 agttttctat tttgtgggtg tactaatgat atatatttta tatgaggtac tgctgatttc
    10021 cagttttgtc ctaaacaaat tagtgtatca cacatacctg gtataataac tccagataat
    10081 tcatcataag caccttttaa tccatattct aaacatgatt gcattattga acatgcaaat
    10141 gcagggaaat attgtttagc taaatctaat tctgtttgcc ctccccatat accaactgga
    10201 agcattccag ctgcatgtat aatttcttct gggcaataaa ctgggaaaca acctatagct
    10261 tttttaccag tttcactttt atattttttt acagccgcat ttggattttc aactacttct
    10321 ttcattttag ataaaatagc ttccattata tctcacctct attaagtttt tttctttctt
    10381 ccattacttc aactaaacct tgaattcttg tttcaaattg agcattagtg aaagctctag
    10441 ggtctgcttg gtcaccatca aatccagcat atggtaatcc agtttcttca gctgctcttc
    10501 tttgcatttc atattgtatt aaactcataa gtttacagct tctgttcata tgatagaatg
    10561 ctccatcaca tttaccctct actaaagaat caactctata ttttgtcata cggtctaggt
    10621 ttacattgtt aaacatagta ctatatgcta ctgccattcc atctaaatca ttaacttcat
    10681 attgtaatgc ccaagcatgt gggtaaacac tacctgtcat gttaactcca aatttagcta
    10741 atgttttcat cttgtatcct atatatggcc aacaaggtat accttccatc attattctgt
    10801 atttttcttc ccctctgaaa gaagatttac cagttttcat gttgtcctct aattcttcta
    10861 taagtaactt aaatgcttct gtagtttctt ttttacctct agcacaaact attacagcca
    10921 tgtaagtaaa taagtcaaat ccattcattg gagaaggaga agaatctgct ggtaaactca
    10981 tagaatactt ccatagtctt ccgttttcag ctgatatttt cattacttct tcaaacttct
    11041 tagggtcaaa tttctttcct gatataattt ctagttgttt tatagcttct tcaaattgag
    11101 ctttaatata atctattctt gattgagtaa cttcgtcttc attattgaaa gttgtatcaa
    11161 tcattattaa aggtatatct aattctcttg aaatattttc ataccatttt ataacttggt
    11221 tacatatatt gttacagcaa agtaggaaat ctggagctgg catatccaaa gcttcacatc
    11281 caccattttc taaaagacca aaatttgttc ttgcatatgc acataggtca atagaatatc
    11341 ctttagattc agctatttca cataattcta aagaaccttt tttagctgct actccagctg
    11401 cttggttttc tggatataat acgtttaagt caaatacttc tgctaactct tgaggaaata
    11461 ctgatgttga ccaacctaca ggtcttcctt cttctttagc tttaaatgca tttgcatatt
    11521 gttcagctaa taaatcatta attactactc tagcttcttt tttttcagac attttcatcc
    11581 ctctttttat atatttttca cttctttttg tgattctttt gcttcatcaa aagcatataa
    11641 cgctgctcct aaagcaccag ttaattgagg tatatcaggt acaataattt ctgtgttgat
    11701 ttctcttgcc atagctctta caataccact atttctagca actccaccaa ccataactac
    11761 atttctttgt actcctattc tttttactag gctagaaact ctctttgcta ctgaagtatg
    11821 aatacctgcc actatatctt caatttttgc attttcagat aaatgtgata taacctcaga
    11881 ctctgcaaat actgtacatg tactgcttat tgatacttca ttttgagaat tcatagatat
    11941 acttccgagt tcagatacat caacctctat tatttttgcc attacatcta aaaatcttcc
    12001 tgtacctgca gcacatttgt cattcataag aaagtttaat agtcttccat tattatctaa
    12061 ttttaatacc tttgcatctt gaccacctat gtcaataatg gttcttgtct ctggaattat
    12121 gaaatttacc cctctagcat gacagcttaa ttcacttatt tgcttatcag catctgaata
    12181 gttcattctt ccatatcctg taactacaac ttttttaata tcttctcttg caagacctgt
    12241 cttgccatat aatttttcta aaactcttga tggtccagta gtcccagtac cagaggatat
    12301 tgtttcagaa gctacaatat cttccccatt ctttaagatt actccctttg atgcagttga
    12361 acctatatct aatcccattg tgtacatctt tagcattctc cttttaaaaa atctagaatt
    12421 actaattaat atcttacaac tttactatct ttaaagttat ttattttctc ttcatcgtag
    12481 cctaaagatt ttaatacttc tacagtatgt tgacctactt ttggtgctgg tgtatattct
    12541 ttaattcctt catttctaaa cataactgga gtattaacta agacacctgt atttccgcta
    12601 tcgtatgttt tcttaaataa gaagtcattt gcccaagctt gttcgtcatc taataaatct
    12661 tcacagcttt gaattttttc aaatggtaag tctgcttctt ctaataaagc tgaccactcg
    12721 tctaatgttt tttctaacat agcttctcca actatcttaa ctaaatcttc aacatgatta
    12781 accattgaat ctatgttatt atatctatca tcttctaata tatattctct atttataacc
    12841 ttacagaatt tgcctaacca cttgttgtat tgtattaaag ctaattgaat ccatcttcca
    12901 tctttacatt tatatgtagt cattaatggg ctgtttggat tttctcttga taaaggcatt
    12961 tcatttccgt attgtgctgt tgttatcatt gttcccattc catatatagc tgtatggaaa
    13021 agacttactg ttactctctc acctttacca gtttgagctt ttttatgtaa tgctgctaaa
    13081 cttcctgctg ctagtgctag acctgcatag tggtcaccaa atcctgctgc tgtatttgct
    13141 ggagatgttc ctttttccat aacagattgg ctaactcctc ctcttgcgaa gtatgcagta
    13201 tagtcaaatc ctggtttatc ttttaaaggt cctttttcac catatcctaa tatttgagag
    13261 aatattaatc ctggatactt atcttttatt tggtcataag ctatacccat tttttctaat
    13321 gcttgaactc taacattagt tacaaatatg tctgcttctg ataataattt atgtaatatt
    13381 tctactcctt cttttgattt tacattaata cttacaccct ttttatttcc attttctaat
    13441 tcaaacatag ggttttcatc atctgatgct ggagatttaa atgttccacc cataactctt
    13501 attccatcac cttctatagg ttcaatctta ataacctctg caccccagtc acctaacatt
    13561 tttgcacaac atggtgctgc gatgaaactt gaaagttcta ctactttaac tccttctaaa
    13621 agcataacgt tttcctcctt aatagtatca attataaaat ttcgattaaa tcactcataa
    13681 aatacttttt tctgatatta actgtctgat gtcaaagttc ctaatcttat ctaaaataac
    13741 ttaaaaatta ttaaaattat tttttattgt tttattgtct tacacctata ttgttaagca
    13801 tttatcgtgc caactttata tttaatcaaa atatcgcttg atttgaatgt tttttaacaa
    13861 tatgcaattg aataatcttt ttcatatcgt ggcatcttgc cactatccat tgcattttgc
    13921 tattctttct atgcttataa aagttttttt tatatatttt tttatgaaaa agcttgacat
    13981 ttcaaaaaaa gttttcattg ctaaactcaa aaacacatgt tatcattgta attaatcagc
    14041 aagttagtta actaatttca aacttagata attttttaat aatatttaat ctaaaaaata
    14101 acaatttctt tgataaattt tagagtaatt attacattaa ataaaaaatt actaaatatc
    14161 aaaataacac agggaaaaca atttcaaaac taaattttta accttaaaaa ttttgtataa
    14221 aaaatataac cttatatgct acatattatt tctaaatgaa aaattaccat aataatttaa
    14281 taattacagg agggtattga tatgaaaata ctagtatttg gagcacgcga ttatgaagaa
    14341 ccagtaataa aaaaatggtc tgaagaacat aaggatgttc aagtggatat ttatcctgaa
    14401 aacatgactg aagaaaatgt agttaaagct aaagggtatg atggtatatc tatacaacaa
    14461 actaactata tagataatcc ttatatttat gaaactttaa aagatgctgg ggttaaagtt
    14521 atagcttcaa gaactgcagg ggttgacatg atacattttg atttagttaa tgaaaatgga
    14581 cttatcgtta caaacgttcc ttcttattca cctaatgcaa tagctgaatt agctgttact
    14641 caagctatga accttttaag aaagactcct ctagtaaaga aaaaagtctg tgaaggtgat
    14701 taccgttgga tagctgaact tcttggaaca gaagttagat ctattacagt tggtgttata
    14761 ggtacaggaa aaataggtgc tacttctgca aaattattca aaggcctagg agctaatgta
    14821 attgcatttg accaatatcc aaatagtgat ttaaatgata tattaactta caaagattct
    14881 ttagaagacc ttctaaaaga agctgacctt ataacattac atactccttt acttgaagga
    14941 acaaaacata tgataaataa agatactcta gctataatga aggatggagc ttacatagta
    15001 aatactggcc gtggtggttt aattaataca ggggatttaa tagaagcact agagtcagga
    15061 aaaattagag ctgctgccct tgatacattt gaaactgaag gattgttctt aaacaaaaaa
    15121 atgaatcctg gagaattaac tgacccagaa ataaataaac ttctttctat ggaacaagtt
    15181 atattcactc atcaccttgg tttcttcact agtacagcga ttgaaaatat agtttattct
    15241 agtttaagta gtgctgtaga agttataaaa acaggaactg ctactaatag agtaaattag
    15301 tattttataa atatattttt tcattaatta gctattatct aacaaaatag cctttaattt
    15361 cccaaatata agagagtcag ctcagtatat attgagtaga ctctcttata ttatttttta
    15421 tattaaactt gtactcttct tattcatacc aaattaaatt tatattaact tattctaact
    15481 actcctactc tatacatttt acctattttt acttttctaa ttatatacat ttgaatgggt
    15541 acaatctgta ttttacaaaa aaaacaccta acaaactatg aaaattgtat gattaatatt
    15601 aatatattta taagaaaaca taacaattat gttagctctg gatttttagg gagggagtat
    15661 attggaaaaa atgaataaag ttacttctaa aaaaactacc tatattgtta cttcagcatt
    15721 atttgcatcc ataatatgcc tgacaatagc atatatatta catattccag ttggtggaaa
    15781 caatggatat gttcatatag gagatgcttt tatttatcta gctgcaacta ttttgccaac
    15841 aaactatgct atagctgctt ctgcaattgg tgctggtcta gctgatttat ctacaggtgc
    15901 tgctatctgg gtaataccaa ctataatcat aaaaccaata cttgtattat ttttcacttc
    15961 taaaagtgac aagataataa ataagagaaa tatagttgct tcggttgtag caggtatagt
    16021 aggattagtt ttatacatgt ttgctgaagg tataattatt ggaagtttta caagtgcatt
    16081 tgtaatgagc ttacttggct tattacagcc aataggaagt tttattgttt ttataatctt
    16141 aggtatggca cttgataaac ttgattttaa aaaacgttat tttaattaag aatttaaatt
    16201 tatggaggga aaattatgaa tatcttatat acaattgaaa atagtatcta tgtaaatata
    16261 actaatacat gtccatgtag ttgtgttttt tgtataagaa acgaaaaaga tgaagttgca
    16321 aatagtggta gtttatggtt ggagcatgag ccaagtgtag atgaagtaaa agaagccttc
    16381 aataaataca atttagacga ctatgatgaa atcgtatttt gtggatatgg cgaaccatta
    16441 atgagaataa atgaattgat agagatagca aagtttataa aagaaaaaag tagcataaag
    16501 ataagaataa atacaaatgg tctaagtgat ttaatacata acaaaaaaac agctattctg
    16561 ttaaaaaatg ttatagatgc agtatcaata agtcttaatg ccccaaataa agaagcttat
    16621 aatagagtta ctcaaccaaa gtttggagaa aaatcatttg attatatgtt agattttgca
    16681 agagattgca aaaaatatat aaaagaagta gctttttcag tagtagatga aatatctcca
    16741 gaagaaatag aagaatctaa acaactggca aaaaaacttg atataccatt aagagttaga
    16801 cataagaatt agcaagtaaa attataaaac attaagaatc acctgaatgg tatttcaggt
    16861 gattcttcct cttgtattaa cattttacaa aatagatttc ataccacact aggaatgtgt
    16921 aaatcatcca aatctttctc caattatcag agtttccact aatgtagtca ttaaaaatct
    16981 cattaatctc atctatgtta aagaatttat ctgctatctc actattgaat ttatctcgga
    17041 tatccttatt atatcggtca tcagccatcc atatacgaat tggcacaata aatcctaatt
    17101 tatttctaaa agcaatctct tctggtaatg tttttgatgc agctgtacga aaggcaattt
    17161 tattctcttt tcctttcact ttatattctg atggtattct ggatgcaata tcaaatattc
    17221 ttgtatctgt aagaggcatt ctgacttcca atcctactgc agtactcatt ttatctatat
    17281 taaaataaat atctccttcc aaccatattt gaatatctac atttgacatg ttagtaagtg
    17341 tatctagttc ttctgtttct tcataaattc cttttaccac ttcaatagga agcacatcag
    17401 gattgtattt cttaagaatt tttcttttct caccctcatt cataatgttt gtatttccaa
    17461 tataaaatgt cttcaaattc tctccataac actctgcctt atggtatata ttatatccac
    17521 caaaaaactc atctgctcct tctccagagt aacagatatt tgtgttttca gctgctgcct
    17581 tgcatccaat agcaaaaacg atagcagatg catctccagt tggttgctcc atatggtaca
    17641 ttacataagg tactgacgca aaatactctt caggtgtaat tatatatctc gaatttttac
    17701 acccaagaat attagctgtc tgttgtgcta attttgattc atcaaaacgc tcttcctcat
    17761 aaccacatga acctgttttt tctatatctg acattgccaa tatataagat gaatcaacac
    17821 ctcctgatag gaataactct gcagtttcat tctctgattt tacctctggc ataattttct
    17881 gaagtgttgt atgaatttca tccgtccatt cctcaataga cttgctgtgg tcaggatgaa
    17941 attcaggttt ccaataacga ccaatacata ctgttttatt ctgatagaca aggtaatgtc
    18001 ctggcataag cttctttact ccacggaaga atgtattttc acctgctaca tatgtgaaag
    18061 acatataaat ctgtaacatg tcttcattta actctttcac aaatcctggt tgctccataa
    18121 tcttacgaat agatgaacca tagagaagct tcccattttc agtctcataa taatagaaag
    18181 gttttacccc aaactggtct cttaggcaga agagtttctt ttccacagta tcccataatg
    18241 caaaagcaaa cattccatgc atgtgatttg ccatatcata tccccatgtc ttatatgctt
    18301 ccactaaaat tgctcgttca cgctcatctc tacataatga agaatcgatt ccaagttctt
    18361 cacaaagaac tttccagttt cgaatatgcc cattgtattc tagaattttt atcatatatg
    18421 tgtcttttcg tgttaaatac ttttcttcta aatttatcat atgtgtatcc tttcgtatta
    18481 aaacatttaa cttctaaatt tattaaatgt ttatatatat ttattcactt ataatcactg
    18541 aaaaatcgac ttttttcaaa gtaaattctt tttgaattag tactaatctg ctctttatta
    18601 atggcataaa tatgattatc aagtattatc agtgttataa cattgaattt tttattcttc
    18661 ataaatattg ccccctttat attaccaact aaatataata tatcttatgt tacttacata
    18721 ttctttaaga aattctgaag attttataaa gttttttgta ttataattaa ttaaaaataa
    18781 aattctagtt ataaaacata ttttccatta aacaaaaaaa tagttaaaat aaattcataa
    18841 ccacataaac ttattttaac tatttgtata ttttaattat aaatattaac ttaaattttt
    18901 aacaggatac actcataaaa taaacataat gaacaacaaa ataatatgtc tcagtttctt
    18961 tatatacttt accttctttc aattttctac catgtagacg tataagataa tattagtaat
    19021 tcactctatt gcttaactcg tgcgatatgt acaaccaaga aagctatttc ctcatttgtt
    19081 aacttttttc catatttctt ttctaaaaaa tctctaactt ttaatgcaat taacatttct
    19141 tttggatttg accttttcat ttgattaaat aataaatcat caccactgct taacatacta
    19201 tctgaaaaaa atctttccac aaaaaatttt atatgtgtta taaatctcat ataatgcata
    19261 ctctttttat ctaaggttct attcaaagaa aaaacaaaaa tattaattat ttctccaatt
    19321 actttggcat acttaatcgt atcatatgaa tttccatctg aagccatagc atttgcaaaa
    19381 tggaaagcaa tgttagctgc ttcttcctct ggtaattgaa tgcccaatct ctcctctacc
    19441 atataaattg caaccattcc aaccttaaac tcatttggat aataattttt tatttcccaa
    19501 aatactcgat ttgtaatttt tattccttta cgcatccttt caattgcaaa gttaaaatgg
    19561 tctgctaata ttaagtataa gtttttatta aaagatgagt tcaataactt ttctgcctct
    19621 actattattt cctgtgttat ctttaaaatg tcgacaggaa tatcatccat taattctaaa
    19681 aattgttttg attttgtatt ttcaacaggg acaaacattt gattatcatt ggaaccacaa
    19741 atatattctc ctgttttttt accatatcca attcctttcc ctagcaaaat aaattcatta
    19801 tactttgcat catgaactaa aacaacgctc gagttcaaaa ctttctttat tatgtagttc
    19861 attttatttg ctcaccttct attggtcatt taaaatctat actattattt tcaattacct
    19921 ttttatacca ataaaaacta tctttcttat atcgattata tgtccccttt ccatagtcat
    19981 cagcatccac ataaatatat ccataacgtt ttgacatttg tttcgttgat tcactgacca
    20041 aatcaataca accccatgaa gtatatcccc aaagttcaac gccatcttcg ataatcgcat
    20101 ctaacataca tttaaagtgt tcttttaaat aattaattct atattggtca tgaacttttt
    20161 tatcttcagt taaaatatct ttagctccca atccattttc aactataaat aaaggctttc
    20221 tgtatctatc atataattca atcaaagata tacgtagacc tattgaatca atttgccaac
    20281 cccattcact catttctaaa taaggatttt ttacagctaa taacgtattc ccaggtgtaa
    20341 tatctaatcc agttgtatca gctgcctcac aagaagacat atagtaagag aatgaaataa
    20401 aatctactgg atactttttc ataatttcat catcatgttc ttcttttact atttgaatgt
    20461 tattattttt aaaatacgac agtaaatata ctggatactc accaaaaacc tgcgtatcac
    20521 tatatgcata aatacttctc attttttgtt gagttgccaa aacatcttct ggtctacatg
    20581 tatatggata atacgttaat tttgttaaca tacaccctac ttttgaattt ggaataatct
    20641 catggcaaat ttttgttgca atggcactag ctacaaattg atgatgcata gcttgaaaaa
    20701 taacttcctc aaagttttta tccttaaaac ggtctcgaac taaaccacca gtagtgtacg
    20761 gatgacgaat catagaatca acttcattaa atgtaagcca atatttcact ttgtttttat
    20821 atctttcaca gatagtttct acatacctaa caaacatatt gataacttgt cgtgaatacc
    20881 atccatcata gtttaaaacg atatttaatg gtggttcata atgtgacata gtaacaagtg
    20941 gttcaattcc ataacttatc aactcatcaa atacatcatc ataaaactgt aaaccttctt
    21001 catttggctc tttatcatct ccatttggaa aaatacgaga ccaagcaata ctcattcgat
    21061 atgtcttaaa tcccatttct gccattagag caatatcttc tttatagtga tgataaaaat
    21121 cactaccatg acgttttgga taatttactt catcttcagg atgtgctaat ccttcttcta
    21181 tatcttttgt tgtgatttca ttattagatt tataatcttt cacatctgca tcaaagtgtg
    21241 cctttgctac atctgataca gaccaccctt tcccacctaa attccaacca ccttcaaatt
    21301 gattagcagc tgtagctcct ccccaaagaa atccttctgg aaattttctc atatttatat
    21361 tcctcccttt acatcaaaca agatacttcc tttttttaca ttgccataag actggtttaa
    21421 cactttataa gcataatctg ctccattatt gtttacaatc ataacagttg aatctaaatt
    21481 agcatgtgag attttgtcta aatcaaattg aattaataaa tctccttctt ttacattatc
    21541 gcctgtctta acaaatgttt taaatccatc tccattcata cttacagtat ttattccaat
    21601 atgaatcaaa atctcagccc cattttttgt tcttaaacca attgcatgtt ttgtttcaaa
    21661 taacatcaca acttctgaat cacaaggtgc gtataaattt ccattggttg gtataattgc
    21721 aactccatct cccaaagtct tacttgcaaa tagttcatca ttaaccttac ttaaatctat
    21781 tacttttcct tctactggag ttactaagat atttacttct ttttcttctt ctagctcttc
    21841 ttcaacaaca tctccaattg atgactctac tgtatttgta tcttccttcc aaataatcag
    21901 tgtaataata aacgagccta atattgcaat aacaaaacca atactcgcaa aaatcaaatt
    21961 gtttccattg tttgggtcaa taaacatact catactggca agccctggtc caacaattac
    22021 aaatcctttt actgcaaata atcctaaaaa ggtaccagaa attgcacttg agaatacaac
    22081 acctaacatt gctcttttat gttgtaaggt aataccatat aaagctggct ctgtaattcc
    22141 catcaaggca gaaattcctg cagataatgc tgtttgtttt aatgtttcat cttttgttcg
    22201 caaggctact gcaaaacaag caccactttc agaaatattg tgggctaatg aagatgtcat
    22261 atataaagct tcataaccca actttccaat tgtattaatt gaataaggta ttagtgcttt
    22321 gtgcattcct gttgcaacca taaatggaag aaaagcagca agtaatccta caactaagaa
    22381 tcccattttg ttatataaga ataaaataat ggttgtaaaa attgtaccaa cgttatatcc
    22441 taaaggacct aaaatagtta gagtaattgg aacagtaatt gccaaagaca tcataggaac
    22501 aaagaaagtt cgaattggtt ttggtgaata cttgttaaaa attttctcca ttgttgccaa
    22561 gaaagacaca cataagatag ccgggaaaac ctgtgcatta taggcaatgt ttggaattgt
    22621 aaatccaaat agttcaacac cttcacttaa agcagttgtt gttgctggaa gcaataagta
    22681 tcctacagcg gcaatagcta ctaaacgatt acatttcaat acattggcag tagttacagc
    22741 taccataaga ggtaggaaat agaatgttgc atctgaaata gcaactaata atgtatatat
    22801 agtagaatct gattttaaaa tattaaacat tgctaataac atcaacagtg attttaaaat
    22861 accagctcct gcaatagcaa aaatcagtgg ttgaaaaata ttaataataa attctataaa
    22921 tcttgttcct aagtttattt tttcttcagt ttttacagta ctatcatttg tatctaaagg
    22981 gcaaactttt aaaatttcat catacacatc aacaacacta tttccaatga caacttgaaa
    23041 ttgtgcccca ttaactatac tcataacacc ttgtactttt tttaaagcat cttgattgac
    23101 tttacttcta tcaatcaact taaagcgtag tctagttgaa cagtgttcta aagctaaaat
    23161 attttttgaa ccaccaactt gttcaataat gtcaatggca gtttttttat aattcatctt
    23221 gtaatctcct tctccataat tttttatgaa tggccattca agatgcaaaa aaggcagaac
    23281 ctatataaac accttgaaaa atcaaagcaa tatattcgat cctgcctgca ttaccagtaa
    23341 catgtcttct atttatacta ttttgtatta ttatattaac atttgcctaa aagaattgtc
    23401 aatacttttt taaattttct gatactaact aatagcacct ttataattca ttttttatgt
    23461 caattaaagt aacagtagcc acccaccaat tagtatcaaa attgaacctg gtattttttc
    23521 ttttatattt tctttgaata taaaatgagc aagtattaaa gttattatca tagatacttg
    23581 agaaaatggc tctgctatac taagttctag attatttaaa gcaattaata atgctaaata
    23641 agaatatcca ttaatagcac cacttaaaat tgaaagcccc tttttattag taaaaatctc
    23701 acaaattatt ttttgtttct ttttaaatgc taaaaagata aataaattta aacctacgaa
    23761 aaaatacagt atagttgaat ataatatagg agatacttgt acaaaaaaag ccttatccaa
    23821 tactcttcct actgactgca aaaatatgta taaaaacatt aatctacatg gtaaattgtt
    23881 aaaaattaca gagacattct ttaaaaaaga acttactttt tttaatataa acactccacc
    23941 aatcataatt atgattcctg caacttttgc taaacttaaa ccttcaccta aaaatataac
    24001 tgataaaagc agtaaaaaca atgaatttaa actatttatt ggagtaacaa gtgaaacttc
    24061 cccagttgct aaagacgtta catacgctac tgaaccaatt gaatagacta aactacttat
    24121 ataacatggt attaaaaacg accaatcact aactctatcc attatgctaa atggaagtaa
    24181 acatactccc cctataaaga aaaatagaaa tgatgaagct atatttttat aaatatctcc
    24241 ttcttcatca cctaataatc ttacaactac tctttcaaaa gctaatagca ctactctaat
    24301 taataatgca aaataagata atatcatttt tgacctcgct taaaaattaa tccgacttat
    24361 tgttatatta actgtataag actaccatat aggtaagtct ttttgatttt ttaatatttt
    24421 atgtttaaat acaggtacat taagtttttc acctagttta cggcattgct ctttataggt
    24481 accttttaat ttatcatgaa aaactataca atcaattcct ccttcaatgc tatttataca
    24541 cttttctagt ttctcaaatc cagattcatc atcatacatt ccacttacaa tccattgatt
    24601 tggcaataca tgtccaattg atatgttata ttctttattt tttataatat ctgagaaaga
    24661 tttctcaaaa tgtacccctc caacacataa caaagtcttc aaaggttcat cacaatcaaa
    24721 tactctaatt aatgattttg ccaatacctg tattgctata ctattattaa aactatcact
    24781 actacttcct atctcaatat ccaacatagg tacagaatat tctgtaatta atttagattc
    24841 ttcaccatat gttgttccag accagtgagt tgcttctgtt aatgtagtaa attcatcaag
    24901 tagattttca ttttttatat cctcaatagc attgattaga tttttaaagt atcttggatt
    24961 tgaatttcca aattctcctg ttggaacatc tccaattgta tgagctgtta ggatatgttc
    25021 tggagcattt tctccctcat gccaatttac aactcctgca aaatcataat ctctaaaatg
    25081 tctatttaaa attggaagat aatatttata attatgactt attacatctt ttgtttttac
    25141 aaaatgaaat aagttattgt ttttatcctt aaactctaat acaaaattat catcaataac
    25201 aatatcagtt tgatttaaat ccattatttc ttcacaacat tttatcacat tactggctac
    25261 tgggtctttc tttaaatcac tgcaaaagaa aaaaactgct tttttattat tcatccataa
    25321 atcacactcc tataacttaa atataatata tcttcatacc taaaatcatc taaatatcac
    25381 tctaattcca ttaaattatt tatatataat atactaccat actcatttta gctatacctt
    25441 tgcctgagtt tctatatata tgtgatacat cagctttaaa tcttatagaa tttccactag
    25501 atacaatgta atcttctcca tttattttaa tggttacttc gccactaaaa acagttataa
    25561 actcttgtgt tcctggaagt tcagcatttg aatctaaatt tccaccttct tctatttcaa
    25621 tcataaatat ctcaaatctt cttttggagt caaatggaaa tattggataa cttatatact
    25681 ttccattatc ttcaataaaa tggtctatat cacttttttg aatcaattct atgtcacttt
    25741 cctgcctctc catcaatgat gtaaatgaaa tttttagccc attagttatt ttcttcaaag
    25801 tagatatagt aggatttacc tcacactttt caatttgaga tagcatactc ttacttacac
    25861 cactaagttg tgcaatcttg tctaaactaa gatgtttttc tttccttatc ttttttaaat
    25921 tttcagcaat tatttcattt aaactttgca taaatacccc ctaatacata ctaatataag
    25981 ataaattatt ttgattatta aataaactta gtaatttaat agaaactttt tatccattat
    26041 aatgtacatt atgtttaata tacattactt tttttagaat gtaaatagtt ttctgaaatt
    26101 ttgtgaaaat gaataaataa aaaactagta acctatattt ttacaaggtt actagctttt
    26161 attataataa tatttcattt taactataaa acttagatgc acctataagc tgtctcttag
    26221 aaacaatctt agctaggttt gctaatgaag aaatttttat atctttaaaa gaaactaaaa
    26281 atacaaactt aaaatctgta aattcttgat ttatattgta tatatcaaaa taacatctca
    26341 aattatcaaa taagtaatta tcctgtaagt ctgcttctat ctcatcagta gcatctttta
    26401 aatacgctct tacatcttca aataaaacac tgaaataaga ctcatctatt tcttcaccta
    26461 actcttccaa tatttcttct atatctaaat catccatatc aaaagaattt cctgtcaact
    26521 ggcaatcaaa taccaatata ttttcttgat ttatagtatt tgatatatct tgtacatatt
    26581 cgaagtctgg acgtaattct aaaatgtctt ttatttcact gctctttaca tggatttttc
    26641 cttttctatt ttcaattttt aaatctatca tatgctcccc ctttcaatct acaaatcttt
    26701 aaataccttg ttttataatc ttttcaatat ctatccaatt actaactcta actatatttt
    26761 gatgtttaac atctttatta tagttagtat ccagaagtat tactttaaca ccatcatcag
    26821 ctagttgcac tgagtttaaa ggattatctt ctataaatat gtcacaactc agttctcttg
    26881 ccttttcaac tttataatca cttcctaata agtaaacatc tatatctgaa aatccttgtc
    26941 tcgatagcca atttttagtt acatcagtta aacactcatg tctagccgtt acaaaagata
    27001 aattatgtcc tttagataat gtgctaatta cctctgtagc accctctaca atctttgctt
    27061 catcatatga gtgtatatac ttattattaa actccgcata cacatctctt attcccgaac
    27121 catacaattc ttcccaatta tgtgttatac actctgcttc agttatattt ttattaaaga
    27181 tatcatttag gtatggaaga aaatgataag ggcttgttat tgttccatct atatcaatac
    27241 atatattcaa tttgttcatt tttacctcca tgtaacattt attgatttga ttaatcaaat
    27301 attatagcac agctttaatt ataaatcaaa actctggata tgactatacc tatataatac
    27361 caaaaagctt gcatatttaa gcaagctttt cgtaaatttt acatttttaa ctaatatata
    27421 agtttttcta aggttggttc cactccaaat tgtgatttca gttctttata ttcttttaat
    27481 gctttgtcat tattcgtttt agtttttatc gctcttatca ttaaattttt tggtgtatca
    27541 agtggagata tgtattctac tacagaagta tcatatccat tgccctccaa taacaatgtt
    27601 cttaaaccat cagttattaa atctgcaaat ctagctttaa atacaccatg ttttaatatt
    27661 ggttccatag cttcatatct atattgccct aataactcct tatgacaaca tggtactact
    27721 actatagctt cagattttgc tctaattcct agacctattg ccatatctgt agctgtatca
    27781 caagcatgta gacttattac aaggtcaaca tccctattag gtgtataatt agtcaaatcc
    27841 tcttttataa atgacatatt tttataaccc aagtttttag ccatattttt tgatgcttct
    27901 ataactacat ctgaataatc tattcctata aaataacagt ttttcttcaa tacttctttt
    27961 atataaaaat ttaagacaaa gcttaagtaa gattttccac aagcacaatc caagatagtt
    28021 atacagtctt tatcctttat ttcttttaaa atactatcta tcaattcaac aaaatggtct
    28081 atctgattgt attttcttat tttatcattt tttatcttac catcttttgt aagtactcca
    28141 atttctttta aaagtgcatt tgcttgtcct acttttacat aataatctct gttttttatt
    28201 tgagatgccg taaattcatc tattttaggt acttcttcct tattatctaa atattttaca
    28261 tttaccttct tattgtctcc ttcaattaca acaatagttc ctcgctcaac atatttaaat
    28321 actaatccat cataattttc tgcctcttta gaaatattct taagcaactc attaaacgta
    28381 tataaatctg attttccttt aaaattaaat ttatatttat tatcttcctc tattgcaatt
    28441 cctttaaact cttttcttcc agatttaaaa atcacctcta actcaataaa aaaatcccta
    28501 ttatcaaggt ttctttgagt aatccccata aaaaacatat ttagttttcc tatactctgt
    28561 ttattcatca taatctccct tttaacttat atctttaaat cttattaatt aatattattt
    28621 gtttctgaat tatttatttc ttcttttaaa tcgttcaatc tatttttaaa actttctatc
    28681 tgcttatctg ataaatcaag atattctgtt atcttcccta tatatttagg gcttttagta
    28741 tttattaatt tcaaagcact ttccatagat ttttctctaa gctcatatgc tttctttacg
    28801 tcatctctag cattactcaa tgtttctgta tacttctcct tagaaagttc tggaatctgc
    28861 atattttcat attcttttac aacttcttta cacttgtttc tggcatttgt aacatctttt
    28921 tttatactag ataatttagt tatatttttt gctatatcct tagtgtaagg tatacattct
    28981 ctcattggaa ctaaagctgc tctttctata ttataaattt ctttcttaaa aattcctata
    29041 ctttccatat ctattttttt tatatcttca ctattttttt ctttacttgt atatttatta
    29101 ttttcttttg tattatcttc ttgtttttct gatttattat tcactgaaac attactatca
    29161 gaattattct tttcttttat atcattactt ccttcttcat tactttcttt attttgtata
    29221 tttctatctt gtttgttgtt taaattttta ttatttgata tttcttcatt ctttttatta
    29281 tcctgtttta aatcagtact ttctttttcc ttaaaatttg atacatactt ttcatcatat
    29341 gtctcatcag aaatataatt gtgataatac atagactctt ttattttatt aagtccactc
    29401 atataaatat tacttatcat tattgttgta gctaatacca cataaatact actgtagata
    29461 caagacctct taaaattctt gtaatttctg aatatcacta ctaaaggaat aagatataaa
    29521 aatataaaaa ctaatatcca cctcataagt cgtgtctcct ttctcaaaac cgaaatccct
    29581 caaatattta tttttaatca tgtatcttat agtatttacc aatttatgtt ttttaatcgt
    29641 gaacttttat taaattaaat tctgtatagt cacaagatgc taatgtatat tctactccat
    29701 ttcgaatccc cttcaatccc attttaaaag attctttacc atgcaagtga ccataaatca
    29761 ccttttcaac attatattct tcaaataact ttgtaaataa agattcttcc aatttatcat
    29821 tcgtaggagg ataatgagta atcacaatta tttttgagtg accactttta cgagcagatt
    29881 ctaatgatag tctaagtcta tgttcttctc ttttataaac tttttcatca gtctcatcaa
    29941 atttaacatc attaggacat atccagcccc tacctccaca aattgcataa tctttatatt
    30001 cataaaaatt tgtctgaata aaacgcatgt cttcatatag cttatttaaa cttgtaacgg
    30061 ttgtccacca gtaatcatga tttcccttta taagtatttt ctgacctgga agtttgctta
    30121 ttatatctaa atctttttta gcttcggata aattaattcc ccaagatgta tctcctagta
    30181 ctaagaccat atcttcttcc ttaacaactt ctttccaatt atctataatt ttcttttcat
    30241 gaccatccca attacttcca aagatattca ttggcttatt gactgatgtt gaaaaatgta
    30301 aatcacctat agcatacaaa ctcataatat cattcctttc ttaattacac taaataggct
    30361 gtctcttttt agaaattatt ttccattaag aggcagcccc attaatattt agcaaatttt
    30421 ctacaagtag tttttactga actactttat catctacctt agtatcctta tattgctcta
    30481 ataatatatc tatttcttgt tttaattcca aaatttcagt tatattttta tctgtttcag
    30541 ttctatcaag ttttctttgg tactgcatag ctttatgtgt atcacccaag tcatataact
    30601 cttgtattct atttaaagta tctctaatag ctatagactt catttggtac atagcctgag
    30661 ctttcattat gtcctctctt atttcactca tttcttggtc taaaagaaag gcagcatcag
    30721 atgctcttct aagcctttca gcaagagtct caggtatgta atggtcatat ttatatttta
    30781 atgaatgttc tattgtagcc cagaaattca ttgcaagagt tcttatttgt atttcacata
    30841 taatttcctt tgaacccgca atggagttta tagggtattt tattataaca tgatagcttc
    30901 tataaccact atctttgtaa tttgtaatat aatctttttc tcctattata gtcatatcat
    30961 ttcttacttt tatcaaatca actatagcat atatatcctc aacaaactgg cacattattc
    31021 ttataccagc aatatcatca atttcagttt ctatatcttt tgcatttatc ctttttaact
    31081 tagatattat ggaagatatt ttttttgttc tacctgtgac aaactctatg ggagaatatt
    31141 caccttttgc taaatattct tttcttatat ttttaaattt tattttcaat tcctctactg
    31201 catgttcata aggtgctagt atctcattcc atttttcgta ttccatattg ctcacccttt
    31261 atttgttttt tatgaccttc tttattttat cataatttat tttgtttttg tatagtaaag
    31321 caattctcca ttttccaata tataccctat ttcttctaaa tcaactaagt aacttatgac
    31381 agatactaac gaagatttaa aaaaatgata ctctttataa ttattgctta aattattgtt
    31441 atttataatg ttttttaata aaatttctaa agatttcggt tctacaagca actctcttat
    31501 ttgatataaa tattttttta aagcattcaa atgtttttct attaatttat aagaatcttc
    31561 tttcgatata acttgcttgc catgccctaa aactaagtac tcaaaatcta tattttttaa
    31621 tttttctaat gaatttattt gttcttgtat atcatataga aacaagaaat cgtattttga
    31681 tagaatttca tctcctatca ataaatcgcc aacaaaaatc acattatcct tcgtcaaaac
    31741 agctatacta ccaggtgtat gaccctgaaa ttcaattata tcaaacattt cattgtttaa
    31801 ttcaattttt ccagcttcta tagatttatc tatttttata tcatccaaca ttttattttt
    31861 taagatatta tccataaata cattgctctt tcccccaaca atatactttg aaaacaattc
    31921 tggattttct atatataatt tatcgtattc agatgacatt atacacacat ctttataata
    31981 ttctttaaat tgattacaag ctccatagtg gtcatcatga ccatgagtat ttataatata
    32041 tctaacctgt atattatttt catctaatac tttatttact ctcctaggtc ttgaaccaca
    32101 taaccctggg tctatcataa gtgctgtgtt atcttcaaat acatatattc ctgtattcgt
    32161 gccacctttt ataaaaaagg tatttccttt tacttttgta agattcacct tcttcacctc
    32221 attttgacaa tatttatgat acaatttatt acttactaat ataaaactat acaagaacaa
    32281 tcctttttat tctatctata gttctttttc ttattttgta ttctttagat atccttattt
    32341 tcacattata tgctaaattt ctataaagta atgactctat aaaatattca actatacctc
    32401 tatccctaaa gtctatatct atatttccac ttgaataaat atttgagtct aatatcataa
    32461 gctcatcaaa aaagcttaat ctcttagatt tacttaaata atctttattt ggaataaatc
    32521 tatcacaata atctatcctg taatttacta cttcatcatt tatttcaaat ccatattgct
    32581 ttttcattaa ctctctatag ttattatttt tctcaataac attatctaaa tttttattat
    32641 aatcctcttt tttccaatgt ccaaacatcc tacaatttaa tggtctaact tcatatatta
    32701 aacatctatt attagtatct ttaaatggac atgggttctt tcttgtatac tcctcaaaat
    32761 aataatctaa tattttactt atacagcttt tttttaaatc aactctatct tcaagataac
    32821 aaaatatatt caagaactca attaaattta tacctactga ctccatacaa caatttccac
    32881 atccagaaca atttcctact ggcaaggact tatatacatc atttagtttg tcaaagagct
    32941 tatttttaat ggaataatct atacaattta aaatatcttt attttttata ctagtcatta
    33001 ttattactcc ttgttataat tattaagtta atacaaacaa ttattataac atatttttta
    33061 aatttaatcg catatggagg tattttatga atagatatac aaaaataatt aatatgatgg
    33121 gaagttatta cacaaaagac tttgaaaaag aaaaaaagaa tgtaataaaa gttagagaag
    33181 ttaaagaaga tacagttaga aaatttttct tacaaggtga ctgtgaagtt cttgtagtat
    33241 ttgaagacac tgggaaagaa atacttattg atgacttttc tcctgaagaa gatatcaaaa
    33301 aatatttagg agcaaaattt ataaataaaa aaagatagtt atcaaaaata attctaaaat
    33361 taaaatttaa taaatgtaca gttataattc tatataatta tagttaaaag ttatctttta
    33421 ttgctttttt agactttaag atagcttttt ttctattttt tgtaaaataa ttccataatt
    33481 cacattaata attcacaaaa tgatataata taacaaatag ataaattttt aaatttctaa
    33541 atacataatt aatattttgc gaggtgattt tatgcaaatt tattttagag ttaaggctgt
    33601 tggcaaacgc aaacctatgc tagaacttac cccttttgat gtatctgaca acatcaattg
    33661 cctaaaagaa gctatctctg aaattgtatc taaaaatgtt cttgaatata atgagaaaat
    33721 cccagaaaaa tcaataataa acttcttaac taatgaagaa attgaatctc aagctgatat
    33781 tggaaaagtt ggatttggct ctatttacaa tgagaataaa caatctgtag aaaaggcaat
    33841 agaggtagcg ttacaggcat ttgaagatgg aatctacaaa gtgcttataa atgaggatgt
    33901 tattgaaaaa ctcgattcct ctataaatct gaaaagtgga gatatattta cttttataag
    33961 acttaccttg cttgctggaa gaatgtttta aaataaataa tttggaggta cataaatgtt
    34021 agaacgtact agagtagaaa aaaatcctaa aataattgaa aattttaaaa ataattttac
    34081 taaatcttct tcaaaacagt actacgactt agcaaagtct ctttgggact gcatagaaaa
    34141 tagttcatac tattatagag aacctgaaga caaattctta aatatgataa agaaatacta
    34201 caattgccac tactacgaaa ttaaaaatat ggacgagctc ctttctggac ctttaaaaaa
    34261 tgcattagaa ttaatattta cttctgaaca agtagaagaa ctttgccaat taattaaaag
    34321 aaagatggat tatacatatt caggaggata ttatcgtaaa gggtatcgct caaataaact
    34381 tgtggattat tttagaggta ttataaggtt tatttcaaac tatgttgatt taatttatta
    34441 tgatttttca gttatagatt atcttactct tccaaataag gtcttgtact atgactctat
    34501 aatgagtgat aaaatagcac tagaaataga caaaggaaat caaaaagtaa taagtgcttt
    34561 agaagaagta atatttggag aaaatcaaac tgctctactt acaagacaaa tgataattgg
    34621 tatcatgaag agtcatagtg ataaatgcta tgaaatgctt tctaaacttc ttttggcagc
    34681 caaacaacaa gaaggactta gacagcaaat tgtagagagt ttagatgagg gtacaatttc
    34741 tgcatcaata tacatgttaa aaactatttt ggacaacaat ttagagcgat ttagttctgt
    34801 tataagagcc ttggatacat ggacaggact tggtttttca gaccaaaaac ctggaataat
    34861 acgtaaatgt ttagaacttt catataaatc attgactgat gaaaagttcc gtatagaatc
    34921 aattaatagc aatgataatc ttgaaattta ttttgcctta tgggctactg caacttacaa
    34981 catatatgac tcttactctc ttattgaaaa cttactttct tgtcaggaaa aatataaaaa
    35041 acttgtagct ctttactttt tatcgcatac agaaagtaca tattttaaac attctatagc
    35101 atctaaaaac attaagggtg atgatttaga gatactagca tgggtaatta caaatttcta
    35161 tgtagaaggt tctgttggct actactatag ttggcaaaac agagaaacta attttgactt
    35221 gtcaaacact cctattgaca aagactttga tgctagaaaa gaacaatttg aaagtttaaa
    35281 acatacttta gaaattttaa attcaaagac aaaatcattt tcaggaagtg tatttccatg
    35341 gacttggatt gaaatttctt ctcatgaaat acttaaatgt atgatgactt taacagcata
    35401 cgatatgaat gctcaattta tagatgtgct tatggaaaat tgtcatctta tgagttcaga
    35461 tttaagagct tcacttatag tcaattttgt aaatgaacca aagacagata gacaacgtga
    35521 atttttattg gaatgtttaa gtgataagag tgtttccaat agagaaacgg tattgagtct
    35581 acttagaaag cttgagctaa cagatgtaga attagataag ataaccaatc tattgtcttt
    35641 aaagacaagc tctattagac aaacagtaat aaaaatttta cttgaacaag atgattcaaa
    35701 tttggaaaat attgcttctt cactgataaa atcttcaaat tctcaaaaat gccttggagg
    35761 tcttgaaatt gtaaacttat taaaagacaa tactgctaga caagaactat ataataagct
    35821 tattttactt atagaggata ttgataaatc taaaaagaat acatctcaag ttcaaatact
    35881 aattgataat ttgttaggta aagcaaaaaa tgattactgc aaagaaaatg gttttggaat
    35941 atataaccct gaaaacaaag ttcaaattcc agaacaattt gattttaaag atgattctaa
    36001 tagctcatca aagcttaata aaattatctc aaatataagt ttatctactc gtgaggattc
    36061 tgtttctgta gcaacaaaaa aagaagcaaa aaaaattctc gatacggata taaataaaat
    36121 aataaaagtt tatgaaaaat ttgatgaact tattactgaa aatgcagatt atgaatatga
    36181 agttgaaaga tggtcaggta atgtagacaa agtactttta ggttattcta cttataactt
    36241 gactcctatt aaatataaag tttctaatga tactcttgat aattatccat tagcagagct
    36301 ttggagagaa actagtaaaa aacttgactt agattacaaa ttaatacttg atatcttatt
    36361 ttatagtata agtacatgtg gatataatga aacagaaaaa agttggtttt catctatata
    36421 ttcaaatgtc cttgactcta aaaaacaaaa taaaatatat acaaaacttg aaaaacttaa
    36481 atttaatgga cttacaagaa aacttttaag agttttacta aatgagtttg accataaaga
    36541 aatatttaac tattgtttag aaatatacta taaacttaga aacttattga ctatagaaca
    36601 atgtaaaaaa caaagagttg aatttactaa aaactattac agacaaaatg aatactgccc
    36661 tgctttaaat gcccctattt taaactattg gcttgataaa gcacattcgt ttatttatga
    36721 tgatatttct tttactaagt ttttctacac tacgttttca aattatcagt tgctagaata
    36781 taagtttcct ttctatacta gcataaatgt gtttgctcgt gcacatgaat taggattaat
    36841 gactgaagag caagttaata gagaaatgat aagtggatac aacgcatcaa atataataag
    36901 aacattgaca aatcctagat gggctggcga cacattagaa aagtaccctt ggcttaaaga
    36961 taatttaaaa actgttacaa accgaattat agaaattgaa tcacgtagag gtgatatgcc
    37021 aacagaagtg tctaatctag ctaataatat acaatacttt gaaggtataa attattttgt
    37081 aaatattttg gtcgctcttg gtaaagaaac tttccagaga ggatattcat atggtagcaa
    37141 ttattcaaaa aaagatgttt taagttctct acttaaaaat tgctatccta ctaaagaaga
    37201 tgattcaaaa aaattaaaaa gtttacttaa aaataccgac attactgagt taagattgat
    37261 agaatctgct atgtatgccc ctcaatgggt aaacataatt gaaaaatatt taaactggaa
    37321 gggtctgaaa agtacaattt ggtacttcca tgcacatata aatgaaggct tctctgcaca
    37381 aaaagaatca gaggttgctc tattctcccc tatttcacca cgtagtttca ttgatggtgc
    37441 atttgatgta gattggtttt tagattcata taaaactatt ggggaagaaa gattcaatat
    37501 actttacaag tcagctaaat atataactag tggtggtaac tctcatagac gtgcacaact
    37561 ctatgctgat gctacacttg gtaagcttga taaagacatg ttgatgaaag aaattgaaac
    37621 aaatagaaat caagataaat tgagaagttt ctctttactt cctatgaaaa aaggagacct
    37681 aaaagaagca actttccgtt atgaatttat tcaaaagttt gctaaagaaa gcaagcaatt
    37741 tggtgcacaa cgtcgtgaaa gtgaatcaaa agcttgtact atagcgctag aaaatctagc
    37801 tagaagtgct ggatttggag atgtaaatcg tatgatgtgg gctcttgaga ctgaaaaact
    37861 aaatgaagtt gctcatctat ttaaaccaaa agatattgat ggtacttcaa tttggataga
    37921 tgttgatgaa aacggaaaag catctactaa agttcaaaaa ggcaacaagt ctttaaagag
    37981 tataccaaaa gctattgcta aacatccata tgtacttgaa cttaaatctg tccaaaaaga
    38041 tttaaagagt cagtattctc gtgcaaaaca gagtttagaa caagctatga aaaatgaaat
    38101 agtatttaca gttaaagaaa ttgccaatat ctataaaaat ccagttatct gccctttgat
    38161 taaaaatcta gtatgggtat gtgatgataa tattggatat gtttataatg ataagtctaa
    38221 gttctttatt tgcaatatag aaggtgaaac ttataagttg acggcaaaaa ataaattaaa
    38281 acttgcacat ccagttcatt tgtttgaatc tggtaagtgg agtgagttcc aacatgattt
    38341 atttagtaag caaattgttc aaccatttaa gcaagtattc cgtgagtatt atagaataaa
    38401 cagtgatgaa ttatctgaaa aaactatatc tcgcagatat gctggtcacc aaattcagcc
    38461 aaagaaaact gtagcacttc ttagaaatca gctttggact gtcgattatg aagagggatt
    38521 acagaaagta ttttataaag aaaatatagt ggcaaagatg tttgcacttg cagattggtt
    38581 ttcaccagca gatatagagc ctcctactat tgaaacagta gaattttttg atagaaaaac
    38641 ttataaaagt ttagaattag cttctatacc tccaattcta ttctcagaag ttatgcgtga
    38701 tatagacctt gttgtaagtg tcgctcatgc tggtggtgtt gaccctgaaa ctagccattc
    38761 tactgtagag atgcgtatag caattgctaa agaactttta ttattattaa aaattaacaa
    38821 tgtcaatttt gaaggctctc atgctcttat agcaggtaat ttaggtgagt attctgtgca
    38881 tatgggttct ggtattgtac ataaaaaagg gatgggtgct ttgaatatac ttcctataca
    38941 ttctcaaagt agaggtaaga tattccttcc attcgctgat gaagacccta aaactgctga
    39001 gattatgtct aagatactat tacttgctga agatagtaag attaaagacc ctagtatctt
    39061 aagtaattta taagtataaa aactatctct aaaatatatt ggactttctt aaaaaaatta
    39121 gaaagtccaa tatatactat actgtaattt atatagatta aatcataatt acaaataatt
    39181 tttatataaa cttctcttat acattatctt tacggtactt attatatcac acaaaaagta
    39241 tttttcttct atcttcacta gaatctttta accctataaa atctatataa aaaatctttt
    39301 tctagagatt tgtttaatat ggcattttct tgaaaattta taaaccttat ctctaatgaa
    39361 gatttattta taggtataac cttatgtata aatcttagat ttactatgta ttgtctatgg
    39421 gtcataaaga aattaggagg taggcgtttt tttaaatcat caaagttctc ataaaacttt
    39481 attatatctt catctttagt gtgtagatta attgctcttg aatttttctc aaacataact
    39541 atatcatcaa aattaatcat atgtatctgc ttccttattt tatatacaaa aagggtgtct
    39601 tctataaaat tattattagc aatcttatgg gagttaatat ggtctattgc tatgttaatt
    39661 gaatcaagta ttttttcttt tttaaatggt ttaactacaa aatctatagg atgcacttta
    39721 aagctttcaa gactataatc agcgaaaccc gtcacaaata ctatatgtat atccttatct
    39781 atagaaagaa tttcttcagc agaatcaatc ccatttttat atggcatatc aatgtcaata
    39841 atcaataaat ctattttctc attttttata aattcaattg cctctatacc atccttaact
    39901 tttttaacat aatctacata tccagactct ttagctatat ttgctatatc atctcttaca
    39961 atcttatcat catcacaaat caaaactttt atcatagact tttctcctcc taactaataa
    40021 tattttggga ttaagattac aaattcagtt aaaaaatcat cactatttac aagtatacta
    40081 taatcatact tatctaatat atttttaact aaatgtagcc catatcccct atcttgtcct
    40141 tctttagtac taaatccatt ccaaaatata ctttcaacat tatgtatttt aggaccatta
    40201 ttttttatag ctataatata ctgaaattca tcttcatatg catgtaatct tatatacttc
    40261 ttttcttttt ttatagtaga caaagactct attgcattat ctattatgtt taatagtact
    40321 gaactcatat cattaggttc aatctctaaa ttatccataa aatcttgaat gtagacatca
    40381 aaagatatat ccttttcaag acattcctcg tattttaatg aagctatagc atctaaataa
    40441 gatacttttc cataccttga attttttgat ttaaagctat ttgatatatt cattatatat
    40501 tctttggcat cttcatctag cccagtattt aatagagaat acactacttg caaatgtttc
    40561 aaatagtcat gtttttgact tcttaatttg ataattatat tatccttatg atttatttta
    40621 ctatctagtt tttgtaattt atattcctgt tcattattat tatttatcaa tcttataact
    40681 ttaaagcctg tataaaaact taaaataatt aaaaccaaaa aaagtataat atttaatact
    40741 ccttcaagta aaaaactata tcctaacctt aattgtatat atttagtgcc ctccataaat
    40801 aaaatcaatg caaaacacga tataaaaaat gttaatatgc ctctttttaa tatgtctaat
    40861 tctttgtaaa atttatactt attcattata agattgctaa atataaacaa agttagtatt
    40921 actataggaa atacaaaatt gttatccatg attcccctcc cctctacaat ttatataggg
    40981 attatatcat tttaaaaaaa ttatgtaaaa agttaaaatt tacatatata ttaattaaac
    41041 ttgtaaaaat acagatgaat ttgtacaatt aactacttaa aatttgaaaa tacttacttt
    41101 gctatatatt ttagataaat atataattga tttagttaag aaaggaagtg gtaaatatga
    41161 aagataattt gaaaatagta ctaaggtata taaaaagtta taaagctagg tctttagcaa
    41221 ttgttgtgag tataattctt gctacatcac tcgttgttgg tattggtact ctctcaagaa
    41281 gtgctcagca agcagatgta gatagattga aaagagagct tggaactgac catgtatact
    41341 ttaaaaatat aaagaaaaat caattaaagt ccataaaatc tagcaaagat attaaaaatc
    41401 tgggtataac atcttactat gcgtctacag atgttaatga aaaattacct ataaacatac
    41461 tatatacaaa taaaaattat ttgactagtc attctaaact tataaaaggt cgatttccaa
    41521 aagctagcaa tgaggtggta gtcgagaaat ggattttaaa tagtatgggc ttaaaaccag
    41581 agataaatca aaaccttact tttaaattat atcaaaaaga aaatccagaa acttttaaag
    41641 ttgttggaat ccttgaagat agatttatag agaaaaaaaa gggacaatgt gaaatttttt
    41701 ctaatctcaa tgaatcagaa ctgaatgatt ttacaactta tattgaattt aatgaaggca
    41761 gtgatataaa tacaaacata gacaatataa taaaaaatgc tatgttagat gagaaaagta
    41821 taggaagaaa ctcaatgctt atagaatcta ctatgaaaaa cggtacttta gataattcaa
    41881 gtaaatacgt tgcaattgct atgagtctat ttgctggtat tgtaatatat agtatctatg
    41941 ttatatcaat ataccaaaga gtacaggaat atggcgtctt aagagctatt ggttccacca
    42001 actttaggat tttcaaactt atgctttatg aacttttcat acttgctcta atagcaatgc
    42061 ctataggtat atgtataggt atgggaggtg cacaaatatt taataggtct gtaggaaata
    42121 ttcaatttga aggaaatata aatgttacac cttttgttat tccagataaa ataattctct
    42181 tatcaattgc atgtacaata ctaataatac taattataag tttctttaca tacttaaaaa
    42241 taagaagaat ttctcctatt gatgctatca gaaaaacttt tggagctgat aaaaatgtaa
    42301 ccaaagttaa ttatttaata tcaaaattaa ctttaaatat gtcagtaaca aaatctatat
    42361 ctgcgaaaaa catctttaga aataaaaagg ggttcattat aattgtatta tctatgagta
    42421 taggaggtat aatcgtcata aaagacaatt ataaatattc ttttttagat gtgcaaaaca
    42481 aatctactca agaacaaaca tatatgaatg cagattttat tctatcaaat gtttatctca
    42541 atgaaattgg taacaatact tcttttaaag atataaaagg gtttaatgat aatcagatag
    42601 ataaaataaa aaatatagat ggaattgaca aagtcaaaac tgctagtatc ttaaacacaa
    42661 gaatagaggt aaataaaata aatagattag attactacga agctataaat tcaactcctt
    42721 attataagct aaatcctctg ttcataaaaa ataagactac tggcaaatat acactaaagc
    42781 aaaagctaaa aggttataat gatgagatga taaagtcatt agaaaaatac ttagtaagtg
    42841 gaaatataaa cttgaaaaaa atgaaaaaag aaaatttagc tattgtatat gtaccagaaa
    42901 tttctaaaac acagaaatac acaaagactt ttactcctgg tgaaggaaca ccagctgtag
    42961 atataaaagt aggtgatact ataaaagtca aatatccaaa gggtgggatg gatacaggtc
    43021 tttatgaaag tctaaaagat aattatgaat acttagaata tgaatttaaa gttggagcta
    43081 ttataagtta tccttttgca gataatggta tgtactctgg agatgatggt gtagatgtaa
    43141 taacgagtag cgaataccta aaaaaattaa ctggtgtaga taagtataac ttagtttatg
    43201 cagaccttaa tgaaaatgca aacaagaaaa aaataaataa ccttttaggt aaaattggaa
    43261 gtgaagttcc tggaactaca acagtagata tgatggtaga aaaagaaaat tctgataaga
    43321 tgacatctag aactatgatt tatagttatg gtatagtagc aataatgttc ataatcagtg
    43381 tacttaacat aataaacaac ataagttata acttaacttc aagaactagt gaatttggaa
    43441 tgttaagagc tattggtatc tctgagagag gctttaaaaa tatgatactt tatgaaggaa
    43501 tattatatgg tgtactctca agtataatta ctatcgtgtc aggaattata atacaattta
    43561 aaatgtatta tatgcagggc tttgtatcat atggattggg attttcaata gattacaaaa
    43621 tatatatact agttgttgta gcaaatataa ttgtaggtat tctagctaca tatattccat
    43681 caagaaagat aaataaaatt agtatagttg aagctataaa cattacagaa taggaggaat
    43741 aattatgcct atattggaaa ctattaactt aggtaagatt tatggaaaaa aggaaacatc
    43801 tgtacatgca ctaaagaatg caaatttaaa aataaataaa ggcgaatttg ttgctataat
    43861 tggaccaagt ggaagtggga aaagtacatt tctacattta gtaggtggtc ttgaaagacc
    43921 aagtaatggt actataaagg tagatggtaa agatatatgt tgtctttcag ataaagaatt
    43981 agcaagatat agaagacaaa aggtaggatt tgtctttcaa cagtataact taattcctgt
    44041 attaaatgta aaggaaaata tagaattacc actaaagtta gacaataaaa aaatagataa
    44101 agaatatatt gatgacctta taaatttatt gggtcttaat gaaaggaaaa atcatcttcc
    44161 caaccaatta tctggtggtc aacagcaaag agttgctatt gcacgtgctt tatctgcaaa
    44221 accaagtata atcctagcag atgaaccaac aggaaatttg gacagtaaaa ctacagaaga
    44281 agtcatggat ttactaaaaa gttctataaa aaaatataac caaacactta taataataac
    44341 acataatgaa aatattgcta gaaaagcaga tagaattata tctataatag atggagagct
    44401 taaattaaca ctctaaaact atttatagaa aagaggattt aaatgttatt gattttaggt
    44461 aatttaaatt taaacttgga ttttgactac agaataataa gagaagaaaa tgaagatgta
    44521 gatatattta tagatattaa ttatcgtagc ttagatatag atactgatgg ttctaactta
    44581 tttaattcta gaatacaatt tccatttgta agagcattga ttctaaggct aaataagaac
    44641 aatcaatgta tgacaattca tttgttaaga gatatagatt tattctctgc ttttgccaac
    44701 tttgaagtgg attatactga ctctataata aatataaaaa atcaaaatga gaaagtaatt
    44761 ttaaataaat ctatcaaaaa atagtaaggg ggccttaata ggccccaatt tttttctttt
    44821 ctaaacttat tatatcatga taaataaatt agtcaataga attttctgaa tatttttata
    44881 attttttcat aaagtttttt atatattatg ctttaaaatt atatgtaata aaaaaatttt
    44941 ccgactaatt ttaaagttaa ttgattaaat acacatattc gaaattacca ttaaattact
    45001 gactttttat catttccatt tagaatttaa attataatct attatttata gttacttcta
    45061 cgtgtctcta ataaaactct atttatattc aaatctaata atttatatac aaacccaata
    45121 gaacctatgt tgcacaatag atattattta ccataataaa cttttagata tatctctttt
    45181 aattcactca tcaatgggta tctaggatta gcacctgtac attggtcatc aaaagcttgt
    45241 tcaaccatag catccaatct ttctaagaat ttagattctt ctactccagc ctcttttata
    45301 gtcttaggaa gacctacttt tgcctttagt tcatctattg cttttataag attatctact
    45361 ttttcttggt ctgtacttcc tttaatacct gcaaaagaag caaattcagc atatctttgt
    45421 atgcaatcag gatatctgta ttgtgagaat gcacccatct tatttggagc ttctgcacaa
    45481 ttgaacttga ttacttcatt tattaataat gcatttgcaa caccgtgttg aacatggtgg
    45541 aatgcaccta atttatgtgc taaagagtga catattccta agaaggcatt tgcaaaagac
    45601 attcctgcca tagtagatgc cattgccatt ttttctcttg cttctttatc attctttcca
    45661 tttttatatg cacgaggtaa atattcaaat attattttac ctgcttgtag tgctagaccg
    45721 tcagctggtt cagttcttaa catagataca tatgcttcta atgcatgtgt taaagcatca
    45781 acacctgatg ctgctgttaa tcttggtggc atctccatca tcatatcagc atcaattata
    45841 gccatgtttg gcattaattc ataatctgct aatgggtact ttacacctga atcttggtca
    45901 gttataactg caaatggagt tacttctgaa ccagttcctg ctgaagttgg gatagcagca
    45961 aaatacgctt tttcacccat cttaggaaat acatatactc tttttcttat atccataaat
    46021 ctcatagcta agtcttggaa atctacttct ggatgctcat acattaccca cattatctta
    46081 ccagcatcca ttgcacttcc tccacctaca gctattatta aatctggttg gaaatcagcc
    46141 atagctttag ctccttctct tgcacaagct aatgttgggt ctggagctac atcaaagaat
    46201 gtagtatgct taattcccat ctcatctaat aaatcagtta atttcttagt atatccatta
    46261 ttatatagga aagaatctgt tactataaat gctttctttt tatccataac atccttaaat
    46321 tctcttgctg ctacacctaa acatcctttt ttgaaataaa ccttttctgg tgctctgaac
    46381 caaagcatat tctctctcct ttcagctact gtcttgatat taagcaaatg ttttactcca
    46441 acgttttcag atactgagtt tccaccccaa gaaccacaac caagagtaag agacggtgcc
    46501 aatttaaagt tatataaatc acctatacca ccttgtgatg atggagtatt aactaatact
    46561 ctacaagtct tcatagcatt tacaaacttt tctactctct ctggatgatt tatagagtct
    46621 gcatataatg aagatgtatg accatagcct ccatctgcaa ctaatttttc tgctttagca
    46681 actgcatctt caaaactttt agacttgtac attgcaagta caggagaaag tttttcatgt
    46741 gcaaaaggtt catttaattc aacagattct acttcaccaa ttattattct agctgttttt
    46801 ggaacttcta catccgccat tttggctatt acatgtgctg gttgtccaac tattctggca
    46861 tttaatgaac catcaattat tactactttt cctacttttt cagtttcttc tttatttagg
    46921 aaatgtgctc cacgatattt aaattctttt ttaacttctt catatatttt ttctggtact
    46981 attacagctt gctcggaagc acatatcata ccattatcga atgattttga tactaagatt
    47041 gaacttacag ccatttttat atctgcactc tcatctatta ttgcaggtac atttccaggc
    47101 ccaactccga cagctggttt acctgaagag tatgcagatt taaccattcc aggtccacca
    47161 gtagctaata taaggtctgc ctctgccatg acaacattag ttaattcaat cgaaggaaca
    47221 tctacccaac ctataagtcc ttttggtgct cctgccttaa ctgctgcatc atgtacaact
    47281 ctagctgctt ctatagtaca gtttttagct cttggatgag gagagaaaat tataccattt
    47341 ctagttttta gtgctattag ggatttgaat attgcagttg atgtaggatt agttgttggt
    47401 ataactgctg ataaaacacc tactggctca gcaattcttg taaaaccaaa tgcttcatct
    47461 ttttctatga caccacaagt tttagtatct ttataagcat tatagatata ttctgaggca
    47521 aaatggtttt ttataacctt atcttcaaca atacccatac cagtctcttc cactgccatt
    47581 tttgctagag gtattctttg ttgattagct gcagttgaag cagctaagaa aatcttatct
    47641 acctgttctt gcgtaaatgt tgcaaattct ttttgtgcca atctaatttc ttctaatctc
    47701 attcttaatg tttcaacact gttgacaatt tcaggactac atacttcaac atttgatttt
    47761 tctactacct tttctttttt ctccatacta aaaacctccc taaaataatt atgcatctct
    47821 aatttttata aatcttaaat gcatcatcta tatttttaac ttatacttaa aataatttta
    47881 tagatttcat ctctatacct tagattttat ttattttact ctcttaggtc aagaagtttt
    47941 tttctgaata ttttgtcaat ttatttttta acaaatatat tatttttttt acttttacta
    48001 aaatttttta tctaaatgag atatatttca tttgaataat ttacttcgac taaataaaat
    48061 actaaaatga taatttatat ctttcatttt ttttacttat taaattttat atgttatttg
    48121 catgttattt gtataagtag taaataaaat ttttgtcgta tttttataaa ataacactta
    48181 tttttgactt gtatgcaatt tttcttttta taacaactgt atagttttaa aaaatatata
    48241 aactaaaatt attctaatct ctataa
//
LOCUS       DAMJWC010000023        47060 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMJWC010000023 DAMJWC010000000
VERSION     DAMJWC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47060
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.023"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(168..416)
                     /locus_tag="PC503_001545"
     CDS             complement(168..416)
                     /locus_tag="PC503_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2527525.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVKDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(447..908)
                     /locus_tag="PC503_001546"
     CDS             complement(447..908)
                     /locus_tag="PC503_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2527526.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            complement(946..1779)
                     /locus_tag="PC503_001547"
     CDS             complement(946..1779)
                     /locus_tag="PC503_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527527.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSWMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(2053..2739)
                     /locus_tag="PC503_001548"
     CDS             complement(2053..2739)
                     /locus_tag="PC503_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527528.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(2754..5231)
                     /locus_tag="PC503_001549"
     CDS             complement(2754..5231)
                     /locus_tag="PC503_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2527529.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGNMNEEFIEDVRHMEGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGVTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(5450..6853)
                     /locus_tag="PC503_001550"
     CDS             complement(5450..6853)
                     /locus_tag="PC503_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527530.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVTLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            7352..8212
                     /locus_tag="PC503_001551"
     CDS             7352..8212
                     /locus_tag="PC503_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2527531.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(8451..9008)
                     /locus_tag="PC503_001552"
     CDS             complement(8451..9008)
                     /locus_tag="PC503_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527532.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(9198..10085)
                     /locus_tag="PC503_001553"
     CDS             complement(9198..10085)
                     /locus_tag="PC503_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2527533.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            10204..11403
                     /locus_tag="PC503_001554"
     CDS             10204..11403
                     /locus_tag="PC503_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF2527534.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(11597..14152)
                     /locus_tag="PC503_001555"
     CDS             complement(11597..14152)
                     /locus_tag="PC503_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2527535.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIEVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(14149..14835)
                     /locus_tag="PC503_001556"
     CDS             complement(14149..14835)
                     /locus_tag="PC503_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527536.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(14912..15820)
                     /locus_tag="PC503_001557"
     CDS             complement(14912..15820)
                     /locus_tag="PC503_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527537.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(15822..16493)
                     /locus_tag="PC503_001558"
     CDS             complement(15822..16493)
                     /locus_tag="PC503_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527538.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            16755..17819
                     /locus_tag="PC503_001559"
     CDS             16755..17819
                     /locus_tag="PC503_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF2527539.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            17977..18663
                     /locus_tag="PC503_001560"
     CDS             17977..18663
                     /locus_tag="PC503_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527540.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            18653..19684
                     /locus_tag="PC503_001561"
     CDS             18653..19684
                     /locus_tag="PC503_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527541.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSRICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            19766..20431
                     /locus_tag="PC503_001562"
     CDS             19766..20431
                     /locus_tag="PC503_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527542.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            20444..22861
                     /locus_tag="PC503_001563"
     CDS             20444..22861
                     /locus_tag="PC503_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527543.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(23042..23833)
                     /locus_tag="PC503_001564"
     CDS             complement(23042..23833)
                     /locus_tag="PC503_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2527544.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(23866..24453)
                     /locus_tag="PC503_001565"
     CDS             complement(23866..24453)
                     /locus_tag="PC503_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2527545.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKSDWNLSI"
     gene            complement(24630..26021)
                     /locus_tag="PC503_001566"
     CDS             complement(24630..26021)
                     /locus_tag="PC503_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF2527546.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(26205..27509)
                     /locus_tag="PC503_001567"
     CDS             complement(26205..27509)
                     /locus_tag="PC503_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF2527547.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNNYY"
     gene            complement(27868..28743)
                     /locus_tag="PC503_001568"
     CDS             complement(27868..28743)
                     /locus_tag="PC503_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF2527548.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDINTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(28947..29633)
                     /locus_tag="PC503_001569"
     CDS             complement(28947..29633)
                     /locus_tag="PC503_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF2527549.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(29682..30215)
                     /locus_tag="PC503_001570"
     CDS             complement(29682..30215)
                     /locus_tag="PC503_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2527550.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(30259..30891)
                     /locus_tag="PC503_001571"
     CDS             complement(30259..30891)
                     /locus_tag="PC503_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF2527551.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(30981..32060)
                     /locus_tag="PC503_001572"
     CDS             complement(30981..32060)
                     /locus_tag="PC503_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2527552.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(32193..33539)
                     /gene="pepV"
                     /locus_tag="PC503_001573"
     CDS             complement(32193..33539)
                     /gene="pepV"
                     /locus_tag="PC503_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF2527553.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELNKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(33608..34888)
                     /locus_tag="PC503_001574"
     CDS             complement(33608..34888)
                     /locus_tag="PC503_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF2527554.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(35015..35275)
                     /gene="hfq"
                     /locus_tag="PC503_001575"
     CDS             complement(35015..35275)
                     /gene="hfq"
                     /locus_tag="PC503_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF2527555.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(35389..36324)
                     /gene="miaA"
                     /locus_tag="PC503_001576"
     CDS             complement(35389..36324)
                     /gene="miaA"
                     /locus_tag="PC503_001576"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF2527556.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(36362..38329)
                     /gene="mutL"
                     /locus_tag="PC503_001577"
     CDS             complement(36362..38329)
                     /gene="mutL"
                     /locus_tag="PC503_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF2527557.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(38340..41183)
                     /gene="mutS"
                     /locus_tag="PC503_001578"
     CDS             complement(38340..41183)
                     /gene="mutS"
                     /locus_tag="PC503_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF2527558.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIENLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALIKQNDDKEKINQVDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(41343..42077)
                     /locus_tag="PC503_001579"
     CDS             complement(41343..42077)
                     /locus_tag="PC503_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527559.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(42046..43059)
                     /locus_tag="PC503_001580"
     CDS             complement(42046..43059)
                     /locus_tag="PC503_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2527560.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(43081..43851)
                     /locus_tag="PC503_001581"
     CDS             complement(43081..43851)
                     /locus_tag="PC503_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527561.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(43826..44116)
                     /locus_tag="PC503_001582"
     CDS             complement(43826..44116)
                     /locus_tag="PC503_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF2527562.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(44247..44346)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      44966..45055
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            45108..45284
                     /locus_tag="PC503_001583"
     CDS             45108..45284
                     /locus_tag="PC503_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527563.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(45399..45755)
                     /locus_tag="PC503_001584"
     CDS             complement(45399..45755)
                     /locus_tag="PC503_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527564.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            46222..46970
                     /locus_tag="PC503_001585"
                     /pseudo
     CDS             46222..46970
                     /locus_tag="PC503_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816229.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
BASE COUNT        16113 a         7308 c         5411 g        18228 t
ORIGIN      
        1 ttaaaatatc taagaaatta ttcaataaaa aaatactatt ttttaaaaat tatcattatt
       61 gataaagctc tactatttat attttttagt gtattcatgt ataataagta aaagcacaac
      121 ggtatatact gttgtgcttt tttgtaatta ataaacaata ttttggtcta taacaatgaa
      181 aaatggctac tttccataat tgatttcatc tgacataagc aaaaagggtg tccagctggg
      241 tcaatcataa ctctccagtc atcagtaaat tgctcctctg cgattgtagc tccacaatga
      301 attgcatatt gaactgcttc ttctaaatcc ttaacagcga aatccatatg agccatttgc
      361 tgttgagatt caggtttttc tggttctatt atgccccaag cctttgtttt ttgcaatata
      421 aagaaaaaat tatatatttt aatattttat acttgttgaa attgtgtaat aaattcaact
      481 ggatacatag tgcgttttga aatttcttct aaagctaaac cttgttttaa aagcctcttt
      541 atgacgcttt ccatactttc tgaaatttct ataatatttt tatcaaaatc ataaaaccta
      601 aaagttcttt gaccccatgg gtattctttt atataatgca aaaattcaat atttcctatt
      661 ctatttatct tactttccca ttgtttgatg tcattaacct caaaatacaa ctgaaagtta
      721 tttgattgtt gatatattgg taaatcatat ccaattatag ctttataatt actttgtaat
      781 ccaaatccat tttcaaatga tacatgttct cctaaatcta atgtgatttt ttgctccata
      841 acatcttcaa aaaacttttt tgatttattt atgtctttga caattagcaa tactcctcca
      901 aatttcatct tatcactatc ctttctttgt tataagtatt ataacttaaa attttgcaat
      961 ttcactgtaa aaatcagaca tattagctcg gtatttttga ggagttattc cacagacaat
     1021 tttaaaatct ttaataaaat gtggtatatc atagaatcct aattcattac atatagacat
     1081 ccatgaagtt ttattattgt ttagaagttt tatagattta ttaatacgta ccaaacgaga
     1141 aaatgacttc atactcaacc ctagatactg attaaagagt ctgtttaaat gcctagaact
     1201 ataaaatact tttttagaaa tttcttgtga agatatattt ccagagtttt gaataatcaa
     1261 ctgaattgcc aaaataaact catatgagta ttcaatttta atattagaaa tcaataattc
     1321 ttccaacttt aaaatcaatt tatctataga taaagattca ttaaatattt ttttaatttc
     1381 taaatctaat gaagtattaa ttatagaaaa tggaacaact ttatcaataa gttcactttg
     1441 ctgtatacct ataagcggga aaaaaccagc aggttgaaat tctataatta gtataacatc
     1501 acatctatta gcaatatttc ctactgtttt tggtttagta gttggaccaa ataatagact
     1561 atgtaaccct gtggcatcat aaaaaaacac caaagttaca cttccatgag gaataatcgt
     1621 gtaattatca gaaattattg tttgatttgg aaacgatata gtaaaattcg atatccaatt
     1681 tcttaattgt atacaaggca agagataaac aaaattgtct tcacaaacta taagtgacct
     1741 atttttattt ataaaatgaa tactttcttt ttttaacata tattatatcc tgtcctatcg
     1801 tgaatattta ttaaagtaag aagaatccat attatctcta tatatcatta actgctttta
     1861 ataatagaga tagtatgaat actcattaga tatttaataa acaaataaaa ttaaaataat
     1921 caataaaaaa tatagtactt ttatctgtta ttttaatatt atagcacatt tatagtattt
     1981 aacttatatc cactttacat atgtctaatt tatataatta aaaatgctta tctcaaatac
     2041 aataattagt ccttatacaa ttaaaccatc tgaaactgta atagtacgac tactactttt
     2101 ggctgcttct ggtgagtgag ttaccataat tatagtttgt ccattgtctc tgtttatttt
     2161 attcagtaaa tctattattt ctatccctgt tttactatct aaatttccag taggctcatc
     2221 agcaaataga atctctggtt ttccaattaa agctcgagct atagcaacac gttgttgctg
     2281 accaccagat aactctcgtg gtgtatgttt acgtctatca gttaaaccaa ctatatctaa
     2341 gatttcatct aattgatttt tataatcttt taaattttta ccatctaata acaaaggaag
     2401 cattatattt tcctccacat ttaaatttgg tattaagtta taaaattgaa atacgaatcc
     2461 tatatttcta cgacgtatta tgctcatttt ctcatcatta aaatgtgata tatcagctcc
     2521 attcatatac acttttccgc tcgttggagt atctaaacca cctaaaatat ataaaagagt
     2581 acttttacca gaaccagatt gacccatgat agaaacaaat tcacctttca ttacttgtaa
     2641 agatacctct tttaacactc gagttgttgt atttccaatt ttatattctt tgataatatt
     2701 ttttgcttct acagctaaac tattatgtgt aattttcata ttaacctcca taattattca
     2761 aacttaattt cttctatcag tttcattttc ttccctttta taataggcac tatcgaacct
     2821 attaaagtta ctataattcc caataaccca acaataataa atgttttaaa atctaaatct
     2881 ggtttcattg aaatttttgg tcctgcaact ataaagatag tttgaatctc aagtatagat
     2941 atcacaatac caataacagc tccaagtaaa cctgaagtaa ccccttcaat caatgttact
     3001 tttatatttt gtttattact tagtcctata gatttataca tagctataga acgtcttttt
     3061 tgaatataat taatcagtag attattaata atacctactg tagcaagaag aaaaatgaaa
     3121 taggtcatct tattcatagg agacaaaaaa ctacttatag tatttaaaga atcattatta
     3181 aattcttcaa ctgtacgact ccaattatat gtatctccaa ataaatatct tatctgaatc
     3241 ataacagcat ctggattgac tgctgtatat actaaaaaac cataattagt tttatcaaaa
     3301 tcattaactg cataatgtga tggtataaca gcttctacat catttgcacg ggatttaaaa
     3361 ctacctacta ttttataaga aaaatcatac ttatcattag atagagttat tgtatctcct
     3421 atagataagc ctactttttt tagagtatct tcattcaaaa taacagaacg tttatcatta
     3481 aaagcttcta ttacttgttt ttttatctca aaatttgtat aattgattcc aaacatagag
     3541 ttatatagtt ttatattatc tgtaccctct agtcttgata atgttacacc attaccagaa
     3601 atctcattat tcataacata aagaggtaat atttttttaa ttccttccat atgtctaaca
     3661 tcttcaataa actcttcatt catatttcca tctgcaaaac cttgtaattc tgcgtcacga
     3721 aacacatctg ttatataagt tttgacaaag ttaccaacaa cacttattgc aataactgca
     3781 gaaatactta taaatagtaa agtgatattc tgtattatat ttttgttatt tttcatattt
     3841 ctagcagcta atttaccctc attccctaaa atatttttat aaacaaactc aaaaactata
     3901 gacatgatat cagtaataag aggaatcaac acaatagtag ctacaattaa tcctagtaat
     3961 gaaaatccac cagctagata caatgtattt tcaggggata ttcttggaag taaaatagat
     4021 aaaataaaca ttatacttcc tataaaaagt atagaacgat ttgaaacatt cttttcttct
     4081 actgttccta gtacaatatt ttttatcggc aaatggctag cttttttaac aggtatatat
     4141 gcactaaatg aagaaacgat tattgctact ataacagata taatcactcc aatgggtgat
     4201 attactactg gaattgatat tccttgttcg agagaatttc ctaacccatg aagcattaaa
     4261 tttaaaacaa ctacaccaat aggaatagca attaatcctc ctatacttcc gtataatata
     4321 ctttcaagca tcaatatacg agttacagtt ttttcattgg caccaatact tctaaatgtt
     4381 ccaataaaag gaagacgttc taatgtaata accttataac tgctgtatat tataaatata
     4441 ctaagggtta atgcaaaaaa acttattaaa aagaaaggca ttgtcttttg tctagcatct
     4501 gaaattatct tagtttcatt tatagtattt gataccatat atttttcagt agaaagttct
     4561 tcggataatt tatttactag attttctgta atttcttctt ctgactctat aagaactctt
     4621 gtatatccac tgcctttatt tataattttt gatagagtct ctttgggtag cagtgcattt
     4681 acacctcttg tgttcctcaa aaatactgta tcataagatg caatatcact aacttgaaaa
     4741 gtataagact ttccataaat ctgcaaagta atagaatcac ctttttttat tttatatttt
     4801 gatgtaaagc gatttggaag aataatttta tcaccagaaa aatcagtaat actatcgcca
     4861 ttttctaatc gtggcttgtt gattttattt agttgactta agtctgctga tataagacta
     4921 aattcttcat agtatccccc tttattataa atagcagagc tttccaatac accaaccttt
     4981 gattttatag tatttaaatc aggtatgtct tctaaattgg ttaatatatc tggattttta
     5041 ctttggacag atatagtcgc tgtaccatac ataccttttg ccatttttct ttgtgcactt
     5101 tcataagata atccaattga gaatgaaaca aaaagtaaaa ctgttgataa aactatggac
     5161 aataacataa ctgctgttct aatttttcgt tctttaatat ttgtgaaaat atactttaat
     5221 ataattttca aacttacacc ttcttccctt atctaagata tttcaatcta atatttttat
     5281 actttaatct aaattaaatc tctaatagac tcctccatac ttttatcatt ctatttataa
     5341 tatttttaat caaatcaccc cttaaataaa aaagattgat aaactactat ataaatataa
     5401 taatctatca accttaatat attttttatt taaccttaat taaccttaat taaataggaa
     5461 aggtgatata aaatgagcta cctaatccag gtatactttc aacagatata ttccctccat
     5521 gaacttcaat aatttgcttc gttattgcta gtcctaaacc agttccttct attttttgtt
     5581 ttgtattgct tcctctataa taacgattaa acaaatttga tgcttcttct cttgacatcc
     5641 cttttccatt atcagatata atgatttcaa ttctttcatt taatgttaca tgtacacaaa
     5701 ctttagtatt tttatctcca tatgtaaaag cattgacaat aagattacta aaagctcgtt
     5761 ttaatagtgt acaatcaaaa tcaaagttaa tattatctat attactctta aattcaacta
     5821 tatttgattc atattctgga taatttaaaa tatcaatgga taattctttc aagaatctta
     5881 ctaaatcata attattttta tttaaaggga ttattccatt ttttaattga taggttaatt
     5941 ttaaatcgtt tataagtgta tttgtatatt ctatgttctt taacatgatt gaagcatatt
     6001 tatatacttt ttcaggtgaa taattagtac tactatctgt aagaagctct gcataccctt
     6061 ttattggtga aagtggagtt tttaaatcat gagttatatt tgaaatccac tcttctctca
     6121 taatatcagt tttattttgt atctcatcac ttttatgaat ttcttcattt aaaatattta
     6181 aactattata tatatcagca aaaacacctt taatattaac tggaagatag cttcgttttg
     6241 aaatatcact aacagcagat gtaatatttg atatgcactt tgttacccag taaccataag
     6301 caattccaga aaccaaaatt attaaaaata taatccctat gattgaaaat acaattgact
     6361 taccacctat aaatttacct ccatcaaaaa acatattcac tttagatata tttaatggaa
     6421 aatatataat ataaatatag tcatttttat tatttttaat tgtattaaag tatacagttc
     6481 cattacttga attattttgg ttagctaatg ctaataattc agaattagaa taataatctt
     6541 tatgctcttt tggttctaaa aacccataaa ctctatttcc actagaatct aaaatttgca
     6601 accacaattg attttctcga agtttttcta atccagactg ttttacttgt ggcttattat
     6661 ctataaatac gatttgttca ttaaagtttt ctgtaaattt tttcggccag tcactacgaa
     6721 taaattcccc atttggtttc tgaatagtaa taagtgataa gaaaatacct attactgtca
     6781 ggattaagca aataaaaatc atgaaaaaaa taatgtatga atgaaatact gttttataac
     6841 taggtttatg catttaatca actcttttct taaactttta ttttagtttg attgttgctt
     6901 atataaaata gacaataatt attgatatgt aaaaatttat ttaaaaatac aactatctac
     6961 ataaattata tttatataat tacatgttat caagctgtct gttgtattta ataaatcatt
     7021 ttgataacat ataaaagtaa gataaatttt tccattaaat accttataat tatacacaaa
     7081 atctctatat acgttaaaca atatagagaa aattttcata gaaccatctt tataggggat
     7141 actttataaa agaataaaaa aattataata tataaaaaac ttcataggag tgtaacaaca
     7201 tcagtaaaga tatgaaaaca ctatataaaa attcaaaaat attaagaata atgaaatact
     7261 tgaaattgct tatatcaaga aattttatat aatataaact ggtcaaatat gttataatat
     7321 taaattgtga caagttcatg gaggtgttta tatgaaaaaa caaaagtcgc caattttact
     7381 tgaaatgctt ggactatttt ttggttgtat atcaatgagt attggtataa atatgttttt
     7441 aaaaccacat acaattgctc ctggaggact tagtggtcta tcattagtac taaacaaggt
     7501 tacaggactt ccagtatcag ctatcatgtt aattataggt gtcccattag taatacttgc
     7561 ttttagaatt atgggtacaa aaaattcatt aaaaacttta tttggaacag ttgtattttc
     7621 agctatagtt caattaacag acccattatc aaaactaaga tttactaatg acttattatt
     7681 gtcttctatt gcaggaggaa tcctagttgg tataggttta ggaataatgt ttaaatcaga
     7741 tgcttctact ggaggaacag acttaattgc actcatactt agtaagaaat tcccaggaat
     7801 aaaagctaca aaattcatgt catgcctaga tggaatggtt gttatatctt ctggtatagt
     7861 aaatcgtagt ttagaaactg ctctttactc tggtatagca ctttgtgtat taataaaaat
     7921 agcagatatg ataatggaag gatttgacca ttcaaaagca ttttttatta tctctgatga
     7981 gcctgaaagt ttaagacaag ctataactga agaacttgat agaggtctta ctattcttga
     8041 tggtaaaggt ggatacacta gagaaaataa agaagttcta ttagtcgtag tttctaaaaa
     8101 acaagaactt tatctaaaga gattagttaa aagaactgac cctactgcat ttgttattgt
     8161 tacagatgta catgaggttc ttggagaagg atttaaaaat ttagagaact aataaaaatt
     8221 aatattttaa gtatatatac tattttaatt aaaatacgat ttattcaaaa agagtgtctc
     8281 ataaactttt tagttcatga gacactcttt tttgtataaa atcaaatgca ttttcagtat
     8341 tttaacaata aaaacaggat tatctatatt ttgaggcaac cactttattg aaattttatt
     8401 tagaaaacaa tcattactaa ataaccagca tagatattaa atgattatat ctattgtttt
     8461 ttcaattcat attgataaca aggaacattt tttacagtat ttccagtatg aatttttttg
     8521 atatactttc ctgtacattt aaatcctaat aaatctaatg attttgtaga attttggttt
     8581 tcttcatagg ttattgcaat tattttattt aagtttagtt ccctaaatcc atactgtatt
     8641 actctttttg ttatctcagt agcaaaatca tgtccccaat agcttggatt tatacatata
     8701 cctatttctg cttctaatgc tttaggattt atattattaa accccatatt cccaataact
     8761 ttattgtctc ttttatatac tatagcaaag tggccaattt tccctttttt atatggattt
     8821 agaaaaaatg attttataaa ctttcttgta tcttctaaag atttatgctc actaaatggt
     8881 aaatgtttta ctactatttt atttttataa cagtcaaaaa aatcttcaac atcatctaat
     8941 gatgcaggtc ttagtataca acttctagtt tctaaggttt tcatttgagg atattcagaa
     9001 tcagacattt ctaatccccc tttatacatt aatctaaata tactgttcat atttaaaata
     9061 cgatattaat tatataaatg ttctcaaatt aaccttattt ttatttttaa taaaaactaa
     9121 ttactatatg aatctttcaa atttacgaat ttatctctat ttttatatta aattacttgt
     9181 gaaatatgta ttctaaatta tatattatta gatatcatgc ttaaaaattc tttggttgct
     9241 aaggataaag atatatcttt taaatggcaa taacctatat ttctcttagg tattggctct
     9301 tttatatcta atttaaacaa tttctcattt tccaaataat ctatgctaaa ttcttctata
     9361 acacaagaca ctccaagatt tatatacgca aattctaaaa gtaattcatg agaacccaat
     9421 tctatatctg ggtttagttt tatacctttt gataaaaaat attcatttac ataaagtctt
     9481 gaatttgctt tattttctag cattattaaa ggcaatgtgt ttaattcttc caatgatatt
     9541 ttcctacctt tgtattctat gtaatcattt gcacatacaa atatatcatg tatttcaata
     9601 cactcaacaa tatttagtgt atcatcttct attggcatgt ttataattgc tatatctata
     9661 ttcccatctt tgagtaaaga tataagttct ctactcgttc tatttattgt agatacatgt
     9721 atatgtggat acttcttatg aaaaatttct aaatatttta acaagaaaaa acgtgcagct
     9781 gtatctccta ctcctatttt cagagaaccg tattctaatt ttttaaattt atttattcta
     9841 tcttctcctg atgatattaa ctttaatgca gtagtgacat gttcacttag aattttcccc
     9901 tctggagtta attttactcc tttattgttt ctataaaata ataaagtatc taattgttct
     9961 tctaattgct ttattgactg gcttacagct ggctgtgaca taaacaattc cttagcagca
    10021 agagaaaaac tcttattatt tacaactgca ttaaaaacct tataaagttc aagttttata
    10081 ttcatatata attactcctt atgtcaaata ttagtattat ttattttact tataattata
    10141 tttgaattat aatatacatg gtactaatat gacaatatta attctttagg aggattttag
    10201 ataatggata gattagttgg aactgtttca agaggggtta gagcacctat tataagacaa
    10261 ggagatgact tagttaaaat agttgttgat tctgttttaa atgcgtcaaa aagtgaaaac
    10321 tttgaagtta gggacaaaga tgtaattgcc gttacagaag ctgttgtagc tagagcacag
    10381 ggaaattatg ctcacgttga caatattgca aaagatgtaa aagataaatt tggagatgat
    10441 actgttggag ttatattccc aattttaagt agaaatcgtt ttgctatatg tttaaaagga
    10501 attgcaaaag gatgtagaaa agtcgtatta atgttaagct acccttctga tgaagttgga
    10561 aatcacttaa taagtattga tgaacttgat gataagggaa taaatccttg gtcagatgtt
    10621 ttaacagaag aaaaatacag agaactattt ggatataaca agcatacatt tactggtgta
    10681 gattatgttg attattataa gaatttaatc aaggattgtg gtgcagaggt agaaatagta
    10741 tttgcaaaca atccaaaaac tattcttaac tatacaacaa gtattttaac ttgtgatata
    10801 catacaagac aaagaacaaa gagaatttta agacaaaatg gagctaaaaa agtatattca
    10861 cttgatgata taatgacagc aagtgtagat ggtagtggtt acaatgacca gtatggactt
    10921 ttaggttcaa acaaagctac agaagaaaca gtaaaattat tccctataaa ttgtgatgaa
    10981 gttgtaaaca aaatccaagg taatataaaa gaaataacag ggaaagatgt agaagtaatg
    11041 gtttatggag atggagcttt taaagaccct gtaggtaaaa tatgggaatt agctgaccca
    11101 gtagtatctc ctgcttatac aaaagggcta gagggaactc caaacgaagt aaaattaaaa
    11161 tacttagcag ataatgattt tgctgactta tctggtgatg agttaaaaga agcaatttca
    11221 aaatacatag ttgaaaaaga taataaatct gatgatttaa caggaaacat ggtttctcaa
    11281 ggtactactc caagaagatt aacagacctt ataggttctt tagcagattt aacatctgga
    11341 agtggagata agggtactcc tattatttac atacaaggat atttcgataa ctatacaaaa
    11401 tagtatgttt taataagatt taattttttt ggattatata tattaacatg aaaatttatt
    11461 aaaacctctt aatagatatg acttttcaag agttatatct attaagaggt ttatttaatg
    11521 ttcacagata agatatattt aaataattta aacaagattg tcagaaagtt atataatctt
    11581 aaaaatttat ataactctaa ttcttattta tttctgaaat aatatcactc ttcaaaattt
    11641 gtcttactgg aataattaca gcaactatac taatagtgat atttaaaata atcataccta
    11701 tgtatagagg tgtatttatt ttaagaattg gatttatata taaatataca cgttttacca
    11761 taaaataaat cataaattgt ccaataacac ttccaattac cattataata cttgcataga
    11821 atccatataa aaaaccttct cttatcatca taagtaaaaa cttattatcc gtaataccca
    11881 tagctcttaa aattccaaac tcatgtcttc ttgaaaaaat taagtagctt actgtattga
    11941 ttatatggaa caaacttatt gcaagaagta caaatacaat accatatata aataagagtt
    12001 tttgatttaa gtaggtatta tttttttcaa tagcaatggt ataatctgtt acgatacatc
    12061 tttttacatc acttacaaca ctttttatgt tctcagacaa ttcctcactg ttactatctt
    12121 ctgtcttttt tatacttact gaattataat tttcgatatc aaagttattt ttcatttgcc
    12181 cattcgtcat aactatatcc ataccataat caccaatgaa atatatgtta tttgccatca
    12241 cacgttttac agtagcagca actacaaatt cttttgttgt ataatcattc ttattttctt
    12301 ctttaaattt aacaatttca tctgttggtt tcattgtctt tggcacttta acttttattg
    12361 tatctcctgg atttatatca actgcatcat acatcccagt tccatccata ggtagtctaa
    12421 ctataacctt attattttta accatatcat gggtattaat ctccccatct ataatataag
    12481 aatttaatcc ttctaacata ccattgttat aaccataaat atttgttttt aaaagatagc
    12541 caccttcatt ttgctttgta caaataccat caaaaaaagt ctttatcctg taatcttttt
    12601 caagaggttt aaagaaattt ttccaaaata gttgttcttc tttaatttgc atagctccaa
    12661 ataaatatct tactggatag acttttgata ttccctcaac attgtttaat cttgaaattt
    12721 tatcttttgg tatacctaca tcaaaatctg ttgtttgcat agttatttgg tagtcagaat
    12781 ttaaaccatc atcagctttc attgtaagtt cattattatt tttagtaagc tgtatagagt
    12841 aactagaaca taaaaatata attccaccaa gtgataatga aaacaaaatt ccaataaaca
    12901 ttcccttttt ttgagtcatg tatttatgag ataatacttt tgtcatgtta gagtgtttta
    12961 cactttctaa tattctcttt ttcttattag taatcttaaa gtttttcata gattctatac
    13021 tagagtattt attcaactga tgtacaacac gtacagcaat taaaattaac aacaataaga
    13081 taaataaaaa gcctaaataa atagattttt cacttataaa aaatgctcct ggaacaatat
    13141 cactactcaa aaatatatgt ggaaattgtt catatattgt agacgccact tcaataccta
    13201 agaagcaacc tataggaaat ccaacaataa aaagtaaaaa taactctaaa aatagtagaa
    13261 ataaaagttg tttattatta gcgcctaata cttctaaaac cccatattgt gatattctct
    13321 gaagtattga aacatggaaa atactatata ctgctgctgc accaaacact ccaacaagta
    13381 atataattgc atttgtattt agttctaaat tttttaagaa ctcaaatata ttatattttt
    13441 ctatattttt tggtggtttt actccaaatt caactgaaag aggccagttt atataagttt
    13501 tttcttttga tatgttgaat tttttcataa atttataatt ttgcttttta atatttttat
    13561 tttcatcata ttttacataa actatataag aatccttttc tttaggctga aaataatcgt
    13621 ttacaaatcc ctccagagca gtttctgggt ttgaaagact tgataaaata ccacataact
    13681 tatagatttt accatctaaa ttgatttctg ttccaatttc tttgtttaca tttaaattgt
    13741 ttagagaata tgtgtcaagt actatctctc catctttact aggaagagtt ccttttaata
    13801 attttctacc tgtcatgtct aaatatgaag aatcagcatt taaaaattct ataataaaag
    13861 gttcatctat ctgattttta ggttttgtaa cgccaagtct atctacagtg tattcctttg
    13921 attttttatt ttttttaatt ttattaagtt gttccttatc tactttatag aaataatgat
    13981 aatctccact atcttccctt atcttttcaa ttctactttt gtctgcacta tgaactaaag
    14041 aaccaattcc cgtcaataat gctactgata gtactatact taaaactata gatatagatt
    14101 gttttttata atgctttata tattgaattg aaaattttac tagagacatc atagtacttc
    14161 accaccagta ttcaccacaa ctccatcttc aatatggata attgagtcgc atacttgtgc
    14221 tatattttca ttgtgtgtta ccataagtat cgtttgatgg aattttgcac tactttcttt
    14281 taataaacat accacttcca ttgtagtttt actatcgaga tttcctgttg gttcatctgc
    14341 taatataagc gcaggtttat ttgccaaagc tctagcaatt gctaccctct gttgttgacc
    14401 accagatagt tcgcttggaa attttaaacg cttatcccaa attcccaatg tcttcatcag
    14461 catttcaata tattcatggt ctatatggtt tcctttatct aatgtaacag gaagagctat
    14521 attatcataa gtgtttaata cgggcattaa actgtagttt tgaaatataa atcctatatt
    14581 tcttcttcta aacactgtca aatctttttt tcctatttta gatatgttct ttcctttaat
    14641 tattacatca cctgaggttg gattatctaa tccacctata atatttaaca atgtgctttt
    14701 tccagaacca gaagttccaa ctatagcagt aaatgtatct cgttcaattt ctatacttac
    14761 tccatttaag gcttttactt tagtctcacc ttttccatag tgttttacta aattattcgt
    14821 cactaatata ctcatttaat ttctcctttc aatacagata tatgttctat aaaatattgt
    14881 aagtgacgat aattacactc atcctacaaa attagtttaa actcttacaa ttctgtaaga
    14941 agatactaaa acaacatcca cttcctagtt tagattctac tataatgttt ccattttctt
    15001 tttctaaaat taatcttgta agatatagac caatccctgt gccattttgg ttttcaacat
    15061 ttttacttct gtaaaatctt ttaaaaatat catttagttc tctactatca atacctattc
    15121 cctcatcttt aatagtaatc ttcgtatata gttccatttt tattacagaa atagtaatcg
    15181 tgctatctga tggtgagtat tttattgcat tttctaaaac atttacaatt gcttctatgg
    15241 tccacttttt attatgaact aattttatgt ctgaaaatgg ttcgagattt atccttatat
    15301 ttttagcttc tgctttatta aagatagtac tgatactttg aataagagta tctttaatta
    15361 gtagttcttc tacttcaaat tctataactc catcctctaa tttagtcatt ttaaataagg
    15421 attgtaacag ccagtcaatc ttaaaagttt catttttcat cttttgtaaa aactccttct
    15481 tctgtaatgt ggaaatattt atattctcca gaagttcaca ataaatggtt atatttgaaa
    15541 gtggagtttt taattgatgt gacatatttg atattaaacc tttaatcgct tctttttctg
    15601 actttgactg ttctacctct atttctatca tatccttaat tttttttact tggtgagaaa
    15661 tttttgacgc tcttgtatcc tttgtatctg gataagtaac ttctttacct tccaatattt
    15721 gatttaacat caaatttaat tcatcatatc tttttcgatt tattttagta gatactataa
    15781 atataacaac tgtacatatt ataaaggcta atataaacat attattctac ctcattccat
    15841 aaataaccca ttccataagc tgtttttata tattttggat tagatgggtc atcctctact
    15901 tttactctaa gtcttcttat atttacagat acaatattat catcaacata attttcttcg
    15961 ctgtcccaaa tatggtgtaa aatttgttcc tttaataata tttgaccttt attttcaatt
    16021 agataactta gaagcttata ttctacagag ctaagttcca aacattcttt atttttatat
    16081 acttttagta acttttggtc caattttatt ccattggaat atattacttt attattcgat
    16141 ttttttctta ttgctacttt gactcttgcc tttaatacag ataaagaaaa tggttttgta
    16201 atgtaatcat caagccctat ttctaatcct tttacttcat caatttctga gtctcttgca
    16261 gtaagcatta taattggtat atctgacttt tcccttatta tttgacatac atcaaatcca
    16321 tctccatctg gaagattgca gtctaagatt ataaaatcta tatttttact attaaatata
    16381 tttaatcctt cttgttttgt ataagcctta aatacattaa atccatcatt ctcaaatgca
    16441 taaaaaagac cttcatttaa gtttatatca tcttcaataa ttaataagtt caattttact
    16501 ctcctttaga ttttttagat aaataattat tttcttgcat tatcatacta aaaatatttt
    16561 aattttattt atttcactaa aaagattgta tttaaatttg ttttcaaaat aaaaacatta
    16621 taatcaagca tatagttata tatttcccaa tttaattacg cttaaattga aaatataact
    16681 ttattcttat ataattaaat tatacaacaa taaagttata ttttttaaat atatttttac
    16741 tagggggaat agaattgaaa agggttgatg agagaaatac tatgtttgca agagcaaatt
    16801 acaaaaaaga tagtactgct tataatgact attataagaa aaatcctgac aaaaaagaaa
    16861 ttgatgatag tataagaaat agaccaaatt tatgtagtga aggaacaatg acttacaatg
    16921 agttaaactc tccaatggca agtagtgcat tcgatttttt atctgatatc aaatctttat
    16981 gcgaaggaaa agtttctgat actaaagtag atgtagatgc aaagtcaatg acaaaaaaaa
    17041 ttaagggtct tgcaaagcag tatggagctt ctgtagttgg tataactaaa ttaaaagact
    17101 atcatattta tacaaatagg ggtagacatg aagaaaatta cggtgaagaa attaatctaa
    17161 ctcataagta tgcaattgta tttggatgtg agatggataa agaaatgata aatagagctc
    17221 caatgatatg tgaagttata gaaacatcaa agtgctatgt ggatgcatct atcgtcggca
    17281 tgattttaag ttactatata agaaatttag gatatgatgc tagaaatcat atggatgcta
    17341 attatttagt aatgcctgtt tttatagctc gtgatgctgg tttaggagat ataggaagaa
    17401 atgctatact tacaaataaa gattatggct ctagacttag attaggtgtt gttactacag
    17461 atattcctct tttagaagat gaatatgttg attttggact agaagatttt tgtaaggtct
    17521 gtaaaaaatg ctcttttaac tgcccttctc attcgctttc taatgatatt aaaattggtg
    17581 atgatggaaa atataattgg gtaattgaac atgagacatg ctatattaaa tggagatatt
    17641 taggtacaga ttgtggtatg tgtatatctg cttgcccatt tagccaaaat ctcgaaacta
    17701 taaagaatac tacttcattt aagggtaata atgagcttat tcaaaaagct ttagatgagt
    17761 atacttcaaa atttggtaaa agaatattta tacctggaaa tccatcttgg ttgaaataat
    17821 tttatttaat aaagaatctg tactagaatt tatcatagga caggttcttt attaaatata
    17881 taaattttta aatacttttt ctcgtttata acaattcagc aatgttttta gtctataatt
    17941 gacattataa aatattaaac taaaaggagt aactgtatgg aaaaaatatt agtagtagaa
    18001 gatgattcta tattaaataa aactctatca tataacctaa ttgaagatgg atatataatt
    18061 acttcaaaat ttacagctaa atctgcacta aagtctattt ttgaatgtga atttgattta
    18121 ataattttgg atattaattt accagataaa agtgggtttg aattatgtaa tgaaataaag
    18181 gaaaattaca atataccaat aattttttta actgctaatg atatggaatg tgatatgatt
    18241 aaaggctatg aacttggagc tttggattat ataacaaaac catttaatat caatatattt
    18301 aaacaaaaaa ttaaagcttt tttaaatcat cttacaataa aaacaaaaca agattactat
    18361 agggatggat atcttgaaat taacttttct gagttatctg ccaatataaa tggaaatcaa
    18421 attatattta caccattaga atatcgtact ttaaaactgc ttactgaaaa tcctaaaagt
    18481 attttaacaa ggaaagtact tttagaaaaa ctctgggata tagatgctaa ctttgtagat
    18541 gaacatactt taacatctgt tataagtagg attagaagca aaattgaaaa agacaatctt
    18601 aagtatatca aaacggtata tggtatggga tatatgtggt taggtgaaag aaatgaattt
    18661 taaaaaattt tcttttagtt ctatttattt aataattgct gttggtataa tttttacagc
    18721 tattttattt agtatctcaa tttatctaat aactgatgat ttaaaactaa ttgctctatt
    18781 attaatatat acaatagtac tttgtggatt tatagcatta ataatatttt tacttcataa
    18841 aaaaatagtt atattttgtt ctagaatatg tcacacttta gatagtatga tgaatagtga
    18901 agataatatt gaaattgaat tagaagaaga aactatttta tcacgtatca atcacagatt
    18961 aattagaatg tatgaagtta ttcaagaaaa tcgcaatagt attgctatag agaaagctga
    19021 tttacaagaa ctagtttctg atatatctca tcaaattaaa actcctattg caaatttaaa
    19081 aatgattaat actactctac taaatcaaac atttaaaaca gaaattcaaa aggatttttt
    19141 aatggatatg gaaaaccaat tagataaatt agatttttta atgcaatcta tggtaaaaac
    19201 ctccagacta gagacaggta taatcacact atctaaaaag aaaaattcaa tttatgaaac
    19261 aattgctaca gcacttagtg gaattttgtt tgatgctgaa aaaaagaata ttgaagttac
    19321 agttgattgt gacccaaatt tatatataat tcatgacaag aaatggactt ctgaagctat
    19381 ttttaatata ttagataatg ctgtaaaata cacaagttct aatggtaaga tacgtgtagc
    19441 tacagaatgt tgggttatgt atacaaaaat agatattatt gataatggaa aaggaatatc
    19501 agaaagtcgc caagcagaaa tctttaaaag attttatcgt gaagaagatg tccatgacat
    19561 agaaggtatt ggaataggtc tctatctttc aagaaaaatt atatctcttc aaggtggcta
    19621 tattaaagtt acatcagata ttggaaaagg gtcgactttt tctattttct tacctaataa
    19681 ataaattttt aaatatttca tttgtaatga ttctgcaaca ttttggtttt atactgtatt
    19741 tacaagatgt taaggaggta ttattatgag tattttacaa gtaattaatt taaagaaata
    19801 ttatggacaa agttcaaaca ttacaaaagc tcttgatggt gtaactctat ctattgaaaa
    19861 aggcgaattt atttctattg taggtacatc tggtagtggc aaatccacat tattaaatat
    19921 gatgggagga ttagataatc ctacatctgg aaaggttatt ataaagggta aggaattatc
    19981 tactatgtct gatgaacagc ttacaatctt tagacgcaga aatataggtt ttatatttca
    20041 aaattataat cttgttcctt tacttaatgt atatgaaaat attatcttac caataggatt
    20101 ggatggagag accatagata aggattttat aaatgaaatt ataaatatgc tttctcttga
    20161 agaaaaatta tatgatatac caagtaatct ttctggtggt caacagcaac gtgttgctat
    20221 agctagagca cttgtaacaa aaccagctat tatactagct gatgaaccaa caggtaacct
    20281 tgatagtaga actagttcag atgtactgag tttacttaaa gtgacaagta aaaaattcaa
    20341 ccaaacaatt gtaatgatta cacacaataa tgaaattgca caactaactg atagaattat
    20401 tcgtattgaa gatggaaaaa ttgttaacta ggaggtgtag tatatgttta gaaataataa
    20461 tcgcacattt ataagaaaaa tagctttaaa tgatttaaaa attaataaac ttaaaacata
    20521 tctttcaggt atcattataa tgatttctac atgtttatta ttaacagtga ccttagtttc
    20581 atataatgcc tctgtagatt tagttaatgc atctccatat catgctatat ataaatctgt
    20641 agatgaaaaa gcaaaaaata tactatataa agataaaaac tttagtggcg taggaactta
    20701 caaattaatt ggaagtaata aaaagacaga ttgtattatg tcgattgttt atgcagatga
    20761 tacagcaatt aaacttatga attttcaacc attgaaaggc aaactaccta caaataaaaa
    20821 tgaaattgct atttcagaaa aatatttaca ggaatttggt ttagataaag atattggaga
    20881 tagcattaaa ttaaattatt atgatgatat tacgaataaa gaagttcaat gtgattttat
    20941 tattgttgga tttctagaaa attattatca agataatgcc aagcaatact atacagtcgt
    21001 ttcaaatgat tattttaaga atatagcttc tacaccttta caaaataaaa gtaatacttt
    21061 tgacgagtca agacctgata ctgtagatgt attagttaaa ctatcagaag aaaatacaga
    21121 gaaagattca gcttcaatta agacacagtt aaataaaatt ggtttatctt taggtattaa
    21181 gaaatataat atatacttaa atgataacta tattgaatca aatttaattg atggtgagca
    21241 gattattaca gttttagtag ttggaatagt tgttcttttt tctagcgttt ttgttatata
    21301 tagtattttt tatatttcag ttgttaattc agttcagatg tatgctaagt tgaaatcgtt
    21361 aggtatgact tcttttcagt taaaaaaaat tatttctcta caaggaaata ttttgtcaat
    21421 tatttttatt ccattagggg ttatagcttc ttgtataatt gcttacataa ttcaaccatt
    21481 agcatggcaa atgatagctg atttatttat aattttaatt ttatcactgg taatgttttt
    21541 aactgttaga atttctttat ttaaaccagc tagaattatt tctaaaatat ctgctattga
    21601 agccatgcaa tatacagaaa ctaaatttag aaaaaaagca aaaaatttta gttatataaa
    21661 tataaaaaat ctagcattaa agaatatcga gtcaaataga aagaaaaatt tgattgcatt
    21721 aatatcgcta agcattagtg gagttttatt tatttcaatc gctaatcttg ctaattcaat
    21781 agatttcaaa aaacaactat ctcaacaatt tgtctataac gaagattata taattagcat
    21841 taagagtgat aacttatatg agcatattac agaaatccaa caaaataatc cactaacaga
    21901 ttctcttaag aatgaaatta aatctattca tggagtaaaa aaattaattg aatccaaatc
    21961 aattaaaagt aatattatag aaccttacat caaagataga gacgaaaaac aatttattac
    22021 tctaattaaa ggtattacgc ctgaactttc aaaatcactt gaagaatata ttgtcagtgg
    22081 aaaaatagac tatacacatt tagattcaga tagtttaatt ataaataaat atagaacaaa
    22141 atattatgga ttaaatttaa aagttggaga tacagttaca tttaatatct ttagtggaaa
    22201 tgatattatt aaaaagaaaa tgaaaattat aggaatcatt gacaattcca atacaggagg
    22261 tatgtttttt gcttcagaca aaactttaga atctctaaca ccatataata caaatttaga
    22321 tttttctatt ttaatagata aaaagcattc taaagaagtt gaagaaaagt tgttaagtat
    22381 aattcagaaa aattcaaatt taatgcttta ttcatatgaa gatgattata gaatgattac
    22441 tagagcattt caatatataa ttatagcttc atacattttt gttggtttaa tttcttgctt
    22501 tggtatacta aatatgacca ataccctaat aaacagcgtt ttaattagaa aaaaagagtt
    22561 tgcattactt caagccgttg gaatgacaag aaagcaactg cgaaatatgc tttatagaga
    22621 aggtctaaac ataagtatca aagctatatg tacttcaagt atactaggtt attttggttc
    22681 aaatctactt tgcactttta taaaagatgt aattagatta gactttatta attttaaatt
    22741 ttctatattt actattttaa ttttttcatt cgtattaatt ggtatacaag ttttagtgac
    22801 tgaattactt gtaagaaata tagaaaaaaa atcacttaca gaacgcttac gttctcagta
    22861 agaatgtata taaaaaatag ccatttttta tacaagtttt aacataattt tttaaaagct
    22921 aaaaggatag aaaattttga ctttacataa ttttctatcc ctatacttgt ttttatttta
    22981 tacagataca cttacttata tctccgagca acatcaccag agacataaac aagcatattc
    23041 cttattttct aaatatgtca attgcatgac ttgtaacccc tactaaatct tcacgttcac
    23101 aagtagcaag gtgatatttt aaatataatg caaatgcatc atcatccata gagtctactg
    23161 cttcacgcat atacaaagcc aaaccatctg atgcgacata atgcagtcta gttacattaa
    23221 atgcagacat caaatcatca atgttttctt tacgtacaag ctcaaacaaa tcctttggtt
    23281 cagacttagc agcaaatgtc tgtggatcaa tcaaaccttt ttcaatatat tcagatacat
    23341 taatatttcc tctatggaac ccctcgtcaa taagacagcc atcagatata acatatgcag
    23401 caaaaaccac accaccaggt tttgttacac gaattgcctc atgtaaagct tgttgtttat
    23461 cttctttgtt ataaagatga tatagtggtc ctaacagtaa cgtaatatca tatttattat
    23521 ctgggaaaac agataaatcc atagcattac cctgagtaat gcttatattt tcatttgatt
    23581 gagtattttt atggaaaacc tctatattat gttcgactaa ttccactgcg tcaacatcat
    23641 atccctgacg tgccagtgtg tgagaataac gaccagttgc agcgccaatt tcaagcacac
    23701 aatcacctga ttttatgtac ttatcaatgt aatgcatagt agtgagaaat tccaccattc
    23761 catgttttaa tgcaagtcga ctatcttcat cataagtatt ataaaagtca attaagtatt
    23821 gttttgtttc cataatttca cctcttctat attagttaat aaacatcaaa tagacaaatt
    23881 ccaatctgat ttttcttgtc ttataaaagc tgttaatata tttttcaaca ttttttcagc
    23941 actatatcta tctaatgtta atttttttgt tgctgttaag acagctatgc catgagtata
    24001 aagaaataaa tctaaaaata ttacttttgc acattccaaa tctattccaa tgctttccga
    24061 aaaaagtctt gccttttttt cattgtcaat ttctttataa aaatcattcg cctctttcat
    24121 catcaaatct aaatcattta taaataacaa cttaaataaa tacgtttctt cttgagcaaa
    24181 ttcaatgtat gaaagcggaa gcagtaaata agggcttaca cttttagaat tacgataatt
    24241 aacaacatac tgattataat attcatatgc aaaagcaaga aattcatttt ttaattcatt
    24301 catgttttca taacaagtaa aaattggtcg agtggaacac tgtaatttac ttgcaatact
    24361 cctcgcattt acagcttcaa atcccacttc tcttgtaata tccaagactg tattcaaaat
    24421 catttctttt gttatcttta ctttaggtgg catatatgtt cacctctcca ttaaattttt
    24481 ataaaacaca tgtgttatat aactatagta acatatcaag aaattatgtc aagaaaaagc
    24541 tttgcatttt tttgcaattc ctaaaactta taaataaaac atgagttgca attaatctat
    24601 taatagataa cagcaactca gattttcctt taaatactct tctttttgtc taatatttca
    24661 tatacacaat cttctattga attaatatct ttttcttttc tttttttaga atcaattaaa
    24721 atgaaataca gtataaaacc tacagcaagt ccccatgttc cgcctttagc agcaattaca
    24781 cctcccataa gtccaatcaa tcccttctca acacctgtat tacatagctc cattgatagc
    24841 tttgtacata aatatccttg aactaaaagt gttactgaca atgctaatgg tataagaggt
    24901 gtagcaatct gcgcaattgg ataaaaacag ataaaaattg ctgaaaccca tactaatgta
    24961 cccatgccac taaaaacaga ctgcatggct tcctttccaa ccttgtacct ttgagcaaca
    25021 cttcctgtaa gtgtcgcagc taatggaccg cacattggta tatatggaga aaagattgcc
    25081 ataaaaatat ttcttatccc acttataaca ttagacctat ttgaattgaa atctatatat
    25141 tcatcttttc tattttcact ttcagaaagt actaagtttt cacctgttat aaaatcacca
    25201 aaggcaatta tgtatatcat aaaagccatt ggtatccctt gtataaataa cattacactt
    25261 ggaaaaccta ttccaaaagg agatactgta tttatcagat ttttaaaatc tactatgtaa
    25321 actaaattgt caaaactaaa tctaggaatt tctatttctt tactaaatat acctactatt
    25381 aaactcacta aaatagctga tactacacca tattctccta aatgaaataa aaatttattc
    25441 ttaactttta gagtatcaaa tctttcagaa aacattacaa aacaagcaac caaaattcct
    25501 actgttatag atataggata agaatcaaat ctccctttag gattaaactc tgatattata
    25561 gtcgatatac cgacacccat tagtattcca cctttaatag aatttggtat cttactaact
    25621 aactttccag ctacaccagt tatacccatt aaaataaata ttattcctaa atctatttgt
    25681 aaagctgtta atgcttgtat tctttcaatg cccatgctga actttaacaa atatgcagtt
    25741 gtaagagtta tagaagctgt aatccagcca ggtacaactg ggtctcccat aaaaacatgc
    25801 aaacagtata atattgagtt aatgatagcc atactccatg ccacttcata gggtaatccc
    25861 aaaatttgtg tactaaggcc aattgtgcct aaacttgtca tacttgatat tataccttga
    25921 atagcttctg gtttctcaaa tctgtaatgt ataaatggaa ttcttatctt aaacattcca
    25981 aattttatat gaggttgttc ccttctagcg agtctttcca taacttcact ccacctttca
    26041 ataactctta taagtttaca actttataat tgtttataaa ttatcaatgt cattaaaatt
    26101 agtatataac atgcaaatta tataaacaat aaattaaatc tataaaattg atagattttg
    26161 tgcatatata gaaagaccgc ttcattttta gttacttaaa tcacttaata gtagttattt
    26221 aaatcacttg ataaaggttt tttataaaat tcaatagttc tattccatga ttcaaactgt
    26281 ccttttgaat ttccttctac agttccacct gaagaaaaaa tccctccact catactcata
    26341 cataaagtct cctttagagg cataatatat ggaattggta acggatgacc catattattg
    26401 tatgttaata attctacgtt atatggataa ttattttctt caaagatttc taatgccttt
    26461 aaacaagctt cataactatt ccatatgtta tcttcttttc cagcaatcat aagtatatct
    26521 gctttggaat tttctatttt tattctagcc tcttttctat tctctgctct tttaagactt
    26581 ttcttataag tactattaaa tccaaatgga ataccttttg atatattttt tttctgttct
    26641 tcaaagaata tatcattgtc tactttgata tatggaaatg gctctccttt atatgaccat
    26701 gatgaagtat catttccact catcaatcca ttaagagctt ggaaacaata aatgtgaggt
    26761 tgtgatacta caaccttttt aatttgttca tatcttgaag caagtaaaaa ggccaattct
    26821 ccaccctttg atgtcccatg tacaaatatt tctttagtac tggtaatttc attttcacta
    26881 atccactcaa atactttttc aaaatattct aatggaacct cttctaattt atctggtaac
    26941 ccttctaaag caaagtatgc aactgttagt acattgaatc ctctagatgc aagtggagct
    27001 gctaaaaggt ctagagcgtc taaatttcca tcagaaccac ctagcattaa aattgtttta
    27061 ttattagaat tttgtttata aaataatttt cctataaact catcagatat atattttgtg
    27121 gtaatatctt ctgatttaaa tattctcttt aattcaactt cttttctttc aatagaagtt
    27181 tcaaatatca tattcataat tattggttta tcaatagata tattttctgc aaaattttta
    27241 ccttcagttt tagatttttc cagcgaataa attaacccca tacaattatc agccttataa
    27301 gtaccttcta taggttcaac taaatctaaa tctacttctc ctttttcatt tgaacaaaac
    27361 actccataag atgaaaattc ttctcccttg caccatggaa attccatttt cacacttatt
    27421 ttaagtttag tatttggaat taagtccgaa accataatct taagtctttc atccacaaat
    27481 gattctacat tgtatacatt tactttcata atctatttct ccttataata attatttatg
    27541 ttttatataa aacagcttta tctaatacaa cataaataaa tttttaaatt aagacaccat
    27601 attgactatt tcattttatc aacatattct atttttgtca acatattgtc ttttttagca
    27661 atttaaaatt atgtagtcta tatgaaatcc agttgatttt tggctaatta aagataggaa
    27721 tgctattagg tttagaatat atatattcaa aataaaaaac cactcatttt aagaatggtt
    27781 tttaatataa actatttgtt attaataagg atattttttt atttaaattt atataatcga
    27841 acatctaata tttaatgttt aataaaatta tgcatttgca aaagtatata tggcattaac
    27901 tcttgctaca tataaattct catcactaca tccaatatat ctagcatatt tttcaatctt
    27961 ttcttttgca ttttcaacat cattttcatc gctctccatt aactcattta tataaatatc
    28021 cattaatgac gctttatatt ctcttatatc atagcctaaa aattcagtca atctctcaat
    28081 ttccttacta aaatctccat cttcttttac caaaaattcg tatacatctt ccctatatgg
    28141 atttaaagtt attatttgtt ttactacttt gcattcgtca gccttcccaa taaaaccatc
    28201 tttataatta ttaaataagg cattagattt ttttatagat tcttcatcaa tataagaatg
    28261 taccgcagtt atacgatttt ctataagggc atctacaaca gcataatgaa ttttaaaaca
    28321 atcattgtat aaataattgc tcattttctt tattgtcgat tctatttcta agaagctcgc
    28381 gtggccattt tttttatttt tatttggtat aataaaagtt ttattcaagt tattaaaaag
    28441 tctcttaaaa tctaaatatt tttcacaata aacactttta aaggtattga tatctatagt
    28501 tataattcca aaacttacta tagtctcaat tcctttctta aaagactctt ctatatattt
    28561 ttctcctaaa cttaaacctc tatcagatat ttgctttaga ttttgaaaac tatttaaaca
    28621 atctctctca aagtttttag atatttccaa agcatataat ttaaagattt tccttatctt
    28681 attataatta ttttttgtat catcaaatct gataatagct ccatttacat caaaagtaat
    28741 cattgagttt taacctcccc attagtttca tcaataaaat aaatttaata taaactttat
    28801 aatcataata ttaaacttat ttatactata attattaatt tgatgataaa agctattttc
    28861 cttctaaata aaaaatttgt ctaaagtttc taaaaaattt agacaaatct taggttatta
    28921 ctctttaaat tatttttaaa ttatttttaa attattccaa atacgccaaa taatattggt
    28981 ataaatatag ctggtaacaa attggctact tttatattcg ttaatttaag tacatttaga
    29041 ccaagtccta taattaataa acttccagct gctgtcattt ctgtgactac aggatcactt
    29101 aaaaatccat ttaaaaatga tgctcccaca catataatac cttcatacaa aaatacagat
    29161 attgcagaaa acattacacc tatacctaaa gaagcagtaa atataattga agctattcca
    29221 tctataacag attttacaaa taaagtatca tgacttcctg taagaccact ttctaatgaa
    29281 ccaactactg ccatggctcc tatacagaat aataaactag atgatataaa accctctgct
    29341 atagaatctt ttttatttcc tttagaaaat ttactttgta aaaaagcacc caacttattt
    29401 acccatttgt caatatctat taattctcct atcagagcac ctacagctac ggatattatt
    29461 gtcactaatg tgttttttcc ttctagtgct cctgatatac caatgtacaa tacacataag
    29521 gcaattccat tcattatagt atcgcttact ctttgaggta atcctccttt tattataaga
    29581 cctactatac atccacctgc aattgctaga ctatttgcta ttactccaaa cattttttct
    29641 cccctcgatt agctaattga aatttatcct attattaaaa cctaaacatc tatactttgt
    29701 attggatatt ttaaatattc caaaaattct tcaaaacctt ttctagatat atttacagtt
    29761 ttagtattta tgttaggatg aaaatttaag taatcttctt taattacatc tttatctatg
    29821 taaagctcaa cttttctttc tgtatcattt attaatgaaa aaggatttac acttccagga
    29881 agaagtttaa gtacattgta tagtctttca ggtgaagcaa acgataatct agaacttcct
    29941 atcttatctt taagtgagtt taaatcaact tgtttttctc ctttaactac aataagataa
    30001 tacttatttc ctttggcatt tcttaaaaat aaatttttac attgacaccc ctttgttatt
    30061 ccatctaaaa tgactaattg ctctgctgta tatacagctt catgctctac tacatcatat
    30121 tcaacattta atttatccaa aatatcatat attttagttt cattcatgct agattcattt
    30181 tcatcttgtt cttttttatt atttaaatca ctcatacttt tctccttaaa cacttcatca
    30241 taatatcatt gtgaggtatt attctactat agctattgct cttactggag ctccatcagc
    30301 atcattatac ttaaatggtg ctgctataaa tagaaatttt tctggaacat tttctaaatt
    30361 tgtaagattt tctatgatta tttttccttt ttcaaataaa atatgatgca cttcaaatac
    30421 tgatgtgtca tatctatcca ctgatagcat atctattcct atgcctttta tattagtatt
    30481 agctatatag tttgcagctt cttttgttaa tgtaggataa cctacatagt actgcttttt
    30541 atcccaaaat tttgaccaac ctgatttaaa tattataaaa tcactatttt ttatttcatc
    30601 ttcatatttt tttagatatt ctaattctat attctcattt cccttttcaa gttccaatac
    30661 ataagctttc ccaacaaaat tttctatatc caacttatct agggtctcac ctttagtata
    30721 catatgtctt ggtgaatcca tatgagttcc attgtgagaa aatacactaa ttaatgtttc
    30781 ttgataacca ttttcttcaa taatagctac tttcttgata tctggtctat taggctctgc
    30841 atatacaggc atgtcattat gtgtcacatg agttaaatca aaaaccttca tctttatata
    30901 ccccctatgt ttttattttc tattatatac ctaaattcat tttatttcta tcagatttta
    30961 ttccattata taccatacta ctatatattt tttataaacc tcaagggatt taccgaaaaa
    31021 tcttggaaag aattatcagt aaatataaca tcttcaccca aaaaacgttt ataccttcct
    31081 tcttctttct ttaaagtaat tctctgtttt tgtgaatgat tattaaaaac cattatctta
    31141 agaggaggtt tttttctatt agtctgcact ctttttaaca tgtattttat gtgcatatca
    31201 gcttcaggaa atgaatatcc acaaaatatt aaaaggtcag tatctcttaa agttttttct
    31261 gtttcattcc aaacattact taaaaatatg tttgacatat tcttaaaata tgttggtggc
    31321 actataatag gttctgttaa ctcaccacac tctaaacatt ttgtctctga actattttca
    31381 ataagcttca tgacaccacc ttcatgtggt gtaagagtta cactattaca aatggggcaa
    31441 taaagccaat tcaatgaccc atgtatctta tataatttga ttaatggttc ttttggtttt
    31501 ctccaattta actcctcttt aaaatttgta aactccacac cataatcaag cataattggc
    31561 aaatcattct tatctcttaa tccagtaact gtattgtcta tatgtatatc ataatttgca
    31621 ctaataaaag tagtatcaag aagcaaatca ttttccaaaa gattttcaac taaaagttta
    31681 tgatatttat tatctgttct aggtgtatta tgaattgctt cagccattag cagtattaaa
    31741 tattgtctta aaaaacgtat actatcactt ctgttattta gattttctag tccaaaattt
    31801 ctaaatgctt cttttctttg ttctgctaag tctaaaagac ctaaaacttc ttcaaaggta
    31861 ggaaaatttg cattatctat attatctttt actatatcaa tattgaacat ctgtttaaag
    31921 aaaatataca attctctatt cattttggta ttataatttg tgggatttag ttttttaaaa
    31981 tattcgctaa aaagttcatt ttgaataggt agattctctg ctgctgaagc tcctgctcct
    32041 aaaaatattg ctattttcat atagttcctc ctaatataaa tattactcct atttttatat
    32101 ccattaaata tccatatcat ttattttatg atacaacaat aaagctgtct tttactagaa
    32161 aaaatcctat tacaagacag ccttatatta tattaaatct ttaataattc gtaaatagaa
    32221 agagcatata tttgagtagc ttttataata tcctctacta ttaagtattc attagcttgg
    32281 tgttctgttt ctggttttcc tggaaaaata gctccaaatg caacacaatt atctaaagct
    32341 cttgcgtatg ttgctcctcc agatgaaagt ggtgttccat caagaccagt ttcttcttca
    32401 tatacttttc taagtgtctt aacaagaaga gtatcttctg gaacatagat tgaatccaag
    32461 aaatcatatt cttcataatt taaattgtat ttatctgtca ttttctttaa ctcttttaca
    32521 aaatcatcct ttttgtatgt tactggaatc cttacatcta ttcctgcaaa ttctttttcg
    32581 ttatcaatag ttactctacc tatatttact gttagtttac ctgatacatc atccttgcag
    32641 ttaggaatta tattgtttcc attagcatct tcaccaataa cttctgctaa aaacttaatt
    32701 atattagaat ctatacctat attattaaga gctatacaaa gtctagccac tgcatttata
    32761 ccagtatcac ttgctgctga atggacactc tttccaatta tacagatttt attaccttca
    32821 acagtatact caaaatttaa tttattaagt tcttttttta atttatcaga gtattttcca
    32881 atatagattg ctttacctgg aactgcattt aaagcctttc caactgacaa ctctatatca
    32941 cttttgctat cacaagtcaa atgaacttgt aaaagacctt tctctgcatt tgttattggg
    33001 aatctagaat ctggagtaaa tccatagttt ggtatttctt cattattttc tttatattta
    33061 tttatacatc tccaaagatt ttcttcatca gccccaaaaa tgaatcttat cctcttatta
    33121 aagtctacat ttaaatccat aagagctttc actgcataaa ttgctgatat tgtaggtcct
    33181 ttatcatctt gtgttcctct tccatacaat ttaccatctt ctaaaacagc ttcaaatgga
    33241 gggtaattcc agctttctaa atcaccttct ggaaccacat caacgtgacc aagtatacct
    33301 atcatttttt caccttgtcc tatttctgca tatccataat atccatcttt gtatactgtc
    33361 ttaaatccta aagatttaca taaatctaat atacctctta aagctttatc tacattttca
    33421 ccaaatgggc aattttcagt tgcttcagat ataacactag gtatttttac actttcttgt
    33481 attgaagaaa tcatttcatc ttgtagagaa tttacttttt ctttaatttg ctctttcata
    33541 ttatcaccct tcaattttca tcataatata ctaataaata ttttgacctt ttaaaaaaaa
    33601 aatatgctta ttttttcagt ttttttataa attcaatcgc ttttaaagtc cccatttttg
    33661 aatggtcaaa tgtaagtcca ccttggaaat aaacattata aggaggtctt attggagcat
    33721 ctgcacttaa ttctatagaa gaaccttgta taaatgctcc tgctgccatt atgacttcac
    33781 tttcgtatcc aggcatgtcc caaggaacag gttttacata agaatcgact ggtgcagctt
    33841 cttgtatacc ttcacaaaaa cttattactt catcagcatt attaagtcta atacattgaa
    33901 taatatcact tcttaagtca tcatattttg gtaatacatc atatcctaat ttttcaaaag
    33961 ctcttgagca aaagatagct cccattacag cctgagatac tatataaggc gccaagaaaa
    34021 aaccctgaag tacatttcta gttgttccaa aagtaagacc acattctttt cctattccag
    34081 gagaagtcat tctataagat ataagctcaa tcaaatcttt tctaccagct atatatccac
    34141 ctgtcaatgc aagcccacca ccaggatttt ttattaaaga gccagccata acatctgctc
    34201 caacatcagt aggctctttg gtatctaaaa actcaccata acaattatca accattacta
    34261 tagcttctgg tttaacagac tttattactt ctatagcttc ttttatatca ctaattgaaa
    34321 gtgattttct ccaagaatat ccttttgacc tttgtatcat aacgagttta gttctatcat
    34381 ttattttgtt tttaattcct tctaaatcta agtttccatc ctctaaaaaa tctacatcat
    34441 catatgtaac accatactct ttcaatgaac ctttttcttc tcttatgcct ataactccct
    34501 ctaaagtatc atatggtcta ccagtaacag ataaaatttc atctcctggt ctaactatac
    34561 cttgtataca taaagtaagt gcatgtgtac catttacaat tattggtctt acaagagcat
    34621 cttctgtatt aaatacttta gaataaattt cctctatttt ttcacgacca atatcattat
    34681 atccatatcc tgtagtccag ttaaagtgca tatcacttag tttagattct tgcatagctt
    34741 ttaaaacttt atattgatta tattctctta tttcttttat ttcttcaaac ttatctttta
    34801 tttcttccat tatttcttgc gatagtttaa aagtatcatc atctattcca tagtagtctt
    34861 ttaataattc ttttgtctca ttaagcattt tatcacctgt ctctttatta ttttatttaa
    34921 acatgtaaag gagactattt tactaaaaca aataaattat agtttataag ttagtataag
    34981 tctcctctca atcatcttaa attaaattaa ttatctatct gttgttatta ttattgttgt
    35041 tttggttttg atttgttaga ttaatatact ttccaggttg tatagttgat acagcatgtt
    35101 tataaatcat gttttgttgt ctattatccc cttctattaa tattatataa ctatcaaacc
    35161 cctttacaag ccctttaact tgcactccat taactaaata tatagtaaca ggtatccttt
    35221 ctttccttgc attatttaaa aacaaatctt gtaaatttaa aactgtattt ttcattagat
    35281 ttgtaccctc ccaagattaa attgaacttc taaaatattc ctaccttata ttctatataa
    35341 gttatgacaa attttcaata ttaagttgta tacttaaaaa tttatatatt attttataga
    35401 atctttaata tataagatta tttcattttt taattcgtct atattttcat attggtctaa
    35461 atcaaaccat tttgctgttt tatatctttt aaaccatgtt atctgacgtt ttgcatacct
    35521 tctagaatct cttttaatta tttcaatagc ttcttcgtat gtatattctc catccagata
    35581 ctttaatatc tctttataac ctataccttg cattgatatc atatcttttt taaatcccat
    35641 acttaaaagt ttttttacct cttcaaccaa tccattttta agcataatat caactctcat
    35701 atttattctt tgatacaaat gttctctatc tctatttaga actattatta ttggttgata
    35761 ttcttcatta aattttaaat cacttgaaaa atcattcatt ttcttaccac ttagacaaac
    35821 ttcaagagct cttatgaccc ttttagtatt gtttttatgg attctattag cagattcttc
    35881 atcaagttct tttaacttat tatgcatgta atctattccc ttttcagcaa gttgtttttg
    35941 aagttcttct cttaattcat tattggcatc agattgtgca aaatccatat tatatattaa
    36001 agagtttaaa taaagtcctg tgcctccagt tactaaaaca catttttcct ttttatttat
    36061 ttcatgtata tatttttttg ctctttgttg aaactctgaa actgaaaatg gatagtcagg
    36121 cttaacttca tctataaggt aatgcttcac tccttgcatc tcttcctctg taacttttgc
    36181 acttccaata tccatatatt catatatttg catagaatca gctgaaatta tctctgcatt
    36241 catatctttt gctaatttta ttgacaaatc tgtttttcca acagcagttg gacctgtaag
    36301 tattataagt ggtatttttt tcataacatt cctttccata tattttaaat atccaaatat
    36361 tttacataat tcttttaaac attttttcta tttctgtctt agatatttcg accattatag
    36421 gtcttccatg aggacatgta aatggattct cacacttttc tagctgttcc aataaacttt
    36481 ttatttcaat atcgtatatt ttatcatttg cttttatagc agacctacat gccatagatg
    36541 caaatctctc tccttttaaa tcataattac ttgtaatttc ttctatatta tcaattattt
    36601 gaagtataaa tttctcggtt tcaggtactc caaatatagt aggaacacat cttaccatta
    36661 tatgattatt gccaaaaatt tctagctcaa aaccaaattt cataaataac tccaagttat
    36721 tttcaatttg aagcatatct acatttgata cttcaataac cactgggtct aaaagtattt
    36781 gcatatttat atcttgtcta tagaacttct ccatatatct ttcatatagt attctttcat
    36841 gtgcagcatg ttggtccaac aaatacatag aatcgtcttt gctcaaaatt atataagtat
    36901 taaatacaac tccaattaca gaatatccgt ataaagaaaa cttgcgtttt gaactacaca
    36961 agtattcttc ttcactgtcc ttaatactat ctcctaagta ataatttcct tcatttttaa
    37021 ttccatcaac ttgaaactct tcttgtatat tatcatttgc actatcttca cttagataat
    37081 taatgttttt tacatcatct tctacacttg catttaggac ttcacttact gattgaaatt
    37141 catttattgg tttttcactt gataaagtaa caacttcaat gacttcatcc ttacctttag
    37201 taatattact atttttagga gtagattcta ataaatcatt atttcttaat ttataatctg
    37261 tacttttttc tctactgtta atagcgattc taggttgtgt ttttttatca ctataagtag
    37321 catattttcc aataagattt gagtgtatta atttaacctt taaaaaatct ctaagttcta
    37381 tatacacttc ttgttctttt tcaaatttaa tttcaagttt attggggtgt atatttacat
    37441 ctatacatga tgggtctact tctatattta agaagcacac tgcatgttta cctattggaa
    37501 ttatagactt ataactttct gttattgcat ctatgattat tttacttttt acaaatcttt
    37561 tatttatata gatatgttgt aagtttttat ttgaacggta tatattgtta ttacctatat
    37621 atccattcat tttaaagtga ttgcacttaa actctacatc tattatattt tccgttattt
    37681 cttttccata tatacttcta atagtgttta caagctttcc atcccctgga gtatttagca
    37741 tctgtttatt gttatttgta tatttaaatt gaatgtttgg attacctatt gcaagtttat
    37801 ttatcaaatc acttatattt atagtttctg catgagtaga ttttaaaaat ttctgtcttg
    37861 ctggtgtatt aaagaaaata tcttttataa tgatggtagt tccattagta gaacctattg
    37921 gttctttcga tattattttt ccaccttcaa catatatttt agttcctatt atttcatctt
    37981 tagttttagt tgtcatttct aattttgata cagctgaaat agatgccaat gcttctcctc
    38041 taaaaccaag agagtataaa tcatacaaat catcaatttt tttaatttta ctagtagcat
    38101 gtctcaaaaa tgatttttca acttcacttg aaggtattcc tattccatta tctgtaatct
    38161 taattagact ttttcctcca tcaattatat ctatggaaat tttatttgca cctgcatcaa
    38221 tggagttttc aataagttct tttactacag aagaaggtct ttctacaact tcacctgctg
    38281 ctatcttatt tatagtcaaa tcatctagga tgttaattat atttttcatt tttacacctc
    38341 taagatttta tttcttttgc ttttctttga agattataaa gagagtttat agcatctaat
    38401 ggagtcatat ttaaaatatc cagatttaaa atttcttctg atagtatatc tctatttaca
    38461 ctatcaaaag agatttgagt taaggctact tcttttacag aatccacttg attaattttc
    38521 tctttatcat cattttgctt tattaaagca acttcatcat ttaatgcttt aaatttagaa
    38581 tttaatttat cataatcctt ttttatatgt ttgtagtctt ttactataag ttcatgttct
    38641 atttttagag attcatattt attcttaaaa ttactttgat ttaccttaac taattcttcg
    38701 tccaaattac tattaattat attattgttt tctttatctc catttattgc aacactgttg
    38761 taaacatgat ttttttccaa gtctttaagt atatattttg ctctttctat gacttcgtct
    38821 ggtaatttag ctaatttagc aacatatatt ccataactct tgtctgctcc ctgaggaatt
    38881 atttttctta aaaatattat tccttcccca tcttctttga ctgctattga ataattttta
    38941 acctctttaa actcttcttc taaatcagta agttcatgat aatgtgttgc aaataatgtc
    39001 ttacatctaa tatttttttg aatatattcc actattgacc atgctaaact tataccatca
    39061 taggtactag ttccacgacc tatttcatct aatataacta aacttctctc tgttgcattt
    39121 tttaatataa gggatacttc gttcatctct accataaaag tagattgacc ttgagataaa
    39181 tcgtcactag ctccaactct tgtaaatatt ctatctaata ttggaatatc agcagactct
    39241 gctggtacaa atgagcctat atgtgccata agagctatta tagcagtttg tctcatatat
    39301 gttgatttac ctgacatatt aggaccagtt attatgttaa taatgttttc tccacgattt
    39361 aaataagtat catttggaac gaaattttcc tctcctacta tattttcgac aacaggatgt
    39421 ctaccatttc ttatatcaag tttattattt tcatttattg ctggttttac atagttattt
    39481 atatgtgcaa ctgttgcaag ggacacaaaa acatctatat tagctatagt cttagccact
    39541 ttttgtattc tatctatgtt tttatatatt gtatctctta tctctacaaa tatctcgtat
    39601 tctaaagatt taatcttttc ctctgcatgt agtatctttt cttctatttc ctttaattct
    39661 ggagttatat atctttctgc attactaagt gtttgctttc ttatatatgt ctcatctagc
    39721 tttgcctgtt taaagttagc ttttgttatt tctatataat atccaaaaac tttattaaag
    39781 cctattttta atgatttaac tcctgttttt tctctttccc tgttttctat ttcctttaca
    39841 agaaaggctc cattcttaga aatctctctt agttccttaa gttcatcact aaaatctgat
    39901 ttaattatgt ttccatcttt tatggttatc gtaggttctt ctagaatagc ttcatctatt
    39961 aaattgtata tatcatctaa tttatccatt tctgaaacat actcttttag gatttttgca
    40021 tttgataaat ttatagtatc ttttaaatta ggtaactttt ctatcgaatt ttttaagtga
    40081 attaactctt ttggtgttac tctctcaaat gctatctttc cacatattct ttctatatcg
    40141 tatatatttt taagtatatc atttaggtct tctcttaata taaagtcatc ttttatttct
    40201 tctattacat ctaatctatt ttcaatttta gatttattta tcaaaggttc ttctacatat
    40261 tttcttaaaa gtctacctcc cattgctgta gaagttttat caagtacgtg taataatgaa
    40321 ccttttttct tattccctct tatagtttga gtaagttcta aattagttct agtaaacata
    40381 tctagaacca tatattctga tgaattgtat atatttatat tattaatgtt agatgttatt
    40441 tgtttttgag tattgtatat ataattcaga agaattgata agcttgactt tattagacct
    40501 ttatcatcaa actttagttt ttgtagataa acatctggaa aatattcttt taatatattt
    40561 atatccaaat agttatcact aaaactttca tttatgtata tattacttac agtagctata
    40621 tctctaagat tttctataaa gtctaaatca tttataatta tttcagttgg atggattttt
    40681 gcaatttctt caattacctt atcttcattt aaacatgttg cattagtttc tcctgtactt
    40741 atatcaacat aagttagacc tatattagta ccatccttat acaaagataa taaataatta
    40801 ttctttttat tttcaagtaa atttccatct aaaactgtac caggagtgat gactcttata
    40861 acctctcttc taacaattcc ttttgctgta gatgggtctt ccatttgttc acctattgct
    40921 actttatatc cattttcaac taattttgat atatatgaat tggctgagtg gaaaggaaca
    40981 ccacacatag gagcacgttc ttctaaacca caagcttttc ctgtcaatgc tatttcaaga
    41041 gcttttgaag ctactaatgc atcttcaaaa aacatttcat aaaaatctcc aagtctaaaa
    41101 aacagtatac agtctttata tctatttttt acttcaagat actgtttcat cataggagtt
    41161 aatttattca tatctatttg cattatcaaa cctccttctt ttctaattaa atattatatc
    41221 atagtagatg attattatta acacaatata taaaattttg acatataact aaaaacaatc
    41281 caaaatgtat actcacattt tggattgcta agtttaatgc ttattaaata aaaatatttt
    41341 ttttacaata aagatattat ttctttttta agtttaatga tattttcaag gttatcttca
    41401 tttaactttc tactatctat aacaaattct ttctttacta ttgatggttt ttttgaaata
    41461 acataaattc tgtttgatag cattatagct tcgtcaatat catgagttat aagaagtatt
    41521 gttgaattta cttttttctt aacatctaaa agccattttt gcatggatgt tttagttaat
    41581 gaatcaagtg ccccaaaagg ctcatctaaa agcattatgt cattagaatt tataaaagtt
    41641 ctcaagaagt tagctctctg tctcattcct ccagaaagtt ctgaaggata tttatcttca
    41701 tatccgctta atccaaacac ctcaaaataa ggttttacca ttgacctagc tttactcttt
    41761 ttttcttttt ttaaaattag tggtagtgac acattatcta ttatagtttt atatggcaag
    41821 agtaaatctt tttgatacat ataactatac ttaccattta tattcacttt gccactatca
    41881 taatctgtaa gtttagttat aatattaaaa atagtacttt ttccacatcc acttggccct
    41941 aatatagaaa caaactcacc ttcataaaca tcaatactta tatcttttaa aacttcaata
    42001 tctttataag tttttgatac attttctata gatactttta cttttttatt gtggtaaaaa
    42061 ttcatttgtg taagcatcac ttgccttcat atccttatct attaatttat attcttttaa
    42121 gaatgatgta tagttgttcc atacactatc tttcatttct ccccatcgtg gtgcatcatc
    42181 tttgtacttg cttgctaaat attcttgact ctttaaagct agtttttcat ctacttcagg
    42241 tgcatgtttt actaaaattt ttgctgattc ttctggattt tttattgcat attcataacc
    42301 ttttgttgta gcttttaaga attttttagc aagctctgga ttatctttaa gcacagtttc
    42361 attagaaatt ataagtggtg tataataatc caatctctca tctaaatctt ttactggtat
    42421 aaagtttaag tcatatccaa ttaaatcagc tttaactgca tcccaacctt caaatatcca
    42481 tgcaaaatct acagttttca tagctgcaaa gaaatcatct tgaccagtat taactatctt
    42541 taacttatta aaatcagctc catttttctt cataactgct ttaaaaacag cttcttctga
    42601 tggagagccc caaccaccat aagtttttcc ttcaaaatct ttagctgttg ttatattctt
    42661 ttcttttggt gatgcaaacc cagaagtatt atgttgtata acagttgcta cagcttttat
    42721 tggaagtgga tcttcactag tctttgcata agtaacttgt tcttgatagc ttataccaaa
    42781 gtcagctttt cctgttgcta ctaaagtttc tgctccactt tcaggtggtt gtactatttc
    42841 aacatccaaa ccttcttctt tatagtaacc cttatcaagt gctacaaata atccagtatg
    42901 atttgtattt ggtgtccaat caagcaccat agttactttt ttagaagaag tatctttatc
    42961 attgtttttg tctttattgt tatttgaaga acatccagtt attgttgcca atgtaaaaac
    43021 acttactaaa cctaatattc ctaacttttt aaaattcata attgcctccc tcaaatacct
    43081 ttaatctatt aatctatgtc ttataacaac tttttttaca gcctgtacaa ttcctacaaa
    43141 cattaaacta aatataacta ctaatatagt agatgcaaat actttatcaa gtgcatatgc
    43201 actttttgac ctaagcatat aaacaccaag tcctttcgtt ccacctagcc attctgcaac
    43261 agttgctgcc attacagcat atgttgcaga tattttaagt ccagaaaaaa atttatccat
    43321 tgccatagga aatttaaggt gaatgaatgt attaacttta tttgagtcca tagtcttaaa
    43381 taaatttaaa taatctttat caatattctc aatgccatct acaaaactta ttaatatagg
    43441 aaaaaaacaa gtaagcatta ccatcaatac ttttggcatt gttccaaatc caaaccatat
    43501 cataaagagt ggtgctataa ttattgtagg tatcatctgt gtaaccaaca taataggata
    43561 aagacatttt tttattattg atacaaaatc catcaatatt ccaattacca atgatattat
    43621 aattgcgact ataaaaccaa gtattgcttc tcctatagta accacagcat gcatggataa
    43681 attttgataa tctttaaaaa acacattaat tatatctact ggtgtgggta gtatatactg
    43741 aggaacttct aaaactccta ccatagattg ccaaagaata agtataaaca aaaatgttgc
    43801 tattggatat atactatctt tgactttatc tatgatttct aagtttttca tctatagtca
    43861 gacctccagc tttttcatct actctagcta ctgttatgac tctttcacat ccaagattaa
    43921 aagggatttt atgtaccttt tttaataatt caaaaacttc atcaaaatca ccttcaacag
    43981 tagtgctcat tgctcctatt tcacatttaa gaccactttt ttcaatttca gcaatacaag
    44041 catctactac tttatacatc tcttcttcac ctttgtaagg tcttagtggc attactgcta
    44101 tgtctgcgat taccatttaa atcactcctt taaaaataat taatacctac taggtatatt
    44161 ttgtttttta ttaaaaaatt ttattactaa aaagatatta tatttaaata aaagaaaagt
    44221 cttatccaaa ataggataag acttattttt atcttaactg gtctccctac actggcatta
    44281 tccaaacagg ttcaaagggt cgagataaaa tctcctctca gcacattagc tccccgaaat
    44341 atattatatc ttttctactt gattatacta cacttatcat attttaacaa attttttatt
    44401 tatattagat attttatccg ttcaaaaata tctaatataa attgtacatt attacaccaa
    44461 ataaattatc ttaaaatggt attttatcaa catcttccaa aactagatta actgaatttt
    44521 ctagttttta ttttgctatt tcaagcatat ttggatgtat atcaattcca tacaaatatt
    44581 gtgctaaatt tctgttttca ctcatctaat ttgcaatcgt tacagattac agattagaaa
    44641 cagtttttag actctactta tctttatcta caaaaaatct ttcaataaat tcattaataa
    44701 tattcagtaa tctaaaaata aacctctatc tggattttta agatacaaac cttttaggaa
    44761 gtatcttttg tgataatata aaaattactc gtcattatca tcaaaatcct cagcaaccaa
    44821 cattttatat aagaatcaaa ctctataata taattatttt atccaattta tttttgagaa
    44881 ataaaatatt tttttaattt ttaaattttt taatatgcac cttgaaaaaa gaaacgtttt
    44941 cctatattat ggtaatagta gaataaaact aaataggcaa aactagagaa atttagtgac
    45001 gcaaagctat agggactaag acttatgaaa tgagttatgt cagccagttg ccaaagagat
    45061 attttctttt tgtttttatg aatgtttttt agggggatat atgatatatg tttatggata
    45121 aaatggatag atgtacacat atactaactg catatatatg cagttcacgc gattactgca
    45181 attttataga tacacaatta aatgatttta tactagaata tggagagaat gtggtagaat
    45241 cttgtttgca tcaagtgatg gtattggtaa gcagatataa ttaaagaaat tttattttct
    45301 agaaaaccct ttttagtttt atctacgttt tataattcat taaagaacta attaaaataa
    45361 gcttcattat atatttttca tgaagtaaac agttaagttt atctcatata ctgtttaccc
    45421 caattacata attctaataa tatagattcc aatgatttac cacgtttagt agacaaatat
    45481 tcaacttttg gaggaatagt cggataagaa atcctcttaa taagtccatc tctttcaaga
    45541 tactttaatt cttgtgacag tatcttatga cttatatgaa caacttcttt ttttaattga
    45601 ctgtaacgta ttggctcttg ttttaaaata tgccataaaa taattgccct ccatttactt
    45661 cctatcacag tcatggtaaa accaattgaa caattaaaat ctttttgtct ttcttcaata
    45721 tttggaaatt cttcaaaatt attatctata tccatctcaa tcctctcttt caaaatagta
    45781 agtatctaac taaaaagtgc attcttgttt agcgtactaa ttcgtaatat aatcttgatt
    45841 aaaaaatagc tatgcacact cgtgacttta gtcatgggag gttcagtgta gcatagagcc
    45901 ttacataata ctactttttt agatgtatat gtttaaattt taatatagac atatgttatt
    45961 ttattaattt tatttaaaca gataataata aataataatt tatctcaagt tttctatgta
    46021 gataaactaa tctaatgttt agaaaggatt atataatatg aataaaaaat ttcgtcttta
    46081 tcaagttgac tcattacaaa agaaaaattt acaggtaatc cagctggtgt aattacaaat
    46141 gctgatggct tatctgaatc acaaatgcaa aaaatagcaa gagaattaaa taattcagaa
    46201 actgctttta ttttcaataa cttggctaaa aatcatcaag aaaattatga tgtacatatc
    46261 agatttttta caccaactaa tgaggttcct atatgtggtc atgctactat tgctgcccat
    46321 tatgttagag caatagaaaa ccaattcaat aacaaaacag tatttcaaaa aactggtgct
    46381 ggaatattac cagttgatat tataaaaaaa gataatgatt atgaaataat tatgacacaa
    46441 ggaaaaattg aagtatctcc accattacaa caaacctatc aaaaaagatt acttaatgca
    46501 tttggtattt aaaggaagat attcgtacag attgtcctat tgccatatca tctacaggac
    46561 attcaaaagt tatgattgga ataaaggaat tatcaacatt aaatagttta tctccaaatt
    46621 tatatgaatt atcgaaaata agtcaagaaa taaaatgtaa tggatattat atttttacat
    46681 tacataataa agaaactcta caagttcatg gaagaatgtt tgctcctgca attggtattt
    46741 cagaagaccc tgttacagga aatgctaatg gacccttagg tgcgtacctt gtacattata
    46801 aagtaatacc tacacccaac acagagttta tatttgaagc agttcaagga gaagcaataa
    46861 aacgcaaagg caagatgtta gtaaaagtaa ttattttaga taataagcca gttgaagtaa
    46921 aaataattgg aaaagctgta attgcattct caacaaacat agaaatctaa ttatagattc
    46981 cttctaagta aatttttgaa ctttttaata ctaatttaat aacaaactaa tttatataca
    47041 atcaaattaa tttttttatt
//
LOCUS       DAMJWC010000024        46716 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMJWC010000024 DAMJWC010000000
VERSION     DAMJWC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.024"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(139..708)
                     /locus_tag="PC503_001586"
     CDS             complement(139..708)
                     /locus_tag="PC503_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2527565.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(780..1388)
                     /locus_tag="PC503_001587"
     CDS             complement(780..1388)
                     /locus_tag="PC503_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2527566.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(1396..3159)
                     /locus_tag="PC503_001588"
     CDS             complement(1396..3159)
                     /locus_tag="PC503_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF2527567.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(3202..3669)
                     /locus_tag="PC503_001589"
     CDS             complement(3202..3669)
                     /locus_tag="PC503_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527568.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            3853..4314
                     /locus_tag="PC503_001590"
     CDS             3853..4314
                     /locus_tag="PC503_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527569.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKV"
     gene            complement(4407..4577)
                     /locus_tag="PC503_001591"
     CDS             complement(4407..4577)
                     /locus_tag="PC503_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527570.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(4766..4987)
                     /locus_tag="PC503_001592"
     CDS             complement(4766..4987)
                     /locus_tag="PC503_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2527571.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(5071..6297)
                     /locus_tag="PC503_001593"
     CDS             complement(5071..6297)
                     /locus_tag="PC503_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2527572.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(6359..7291)
                     /locus_tag="PC503_001594"
     CDS             complement(6359..7291)
                     /locus_tag="PC503_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF2527573.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(7380..7907)
                     /gene="hpt"
                     /locus_tag="PC503_001595"
     CDS             complement(7380..7907)
                     /gene="hpt"
                     /locus_tag="PC503_001595"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2527574.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            8136..9212
                     /locus_tag="PC503_001596"
     CDS             8136..9212
                     /locus_tag="PC503_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2527575.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(9298..10506)
                     /locus_tag="PC503_001597"
     CDS             complement(9298..10506)
                     /locus_tag="PC503_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2527576.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(10667..11056)
                     /locus_tag="PC503_001598"
     CDS             complement(10667..11056)
                     /locus_tag="PC503_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF2527577.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(11160..12161)
                     /locus_tag="PC503_001599"
     CDS             complement(11160..12161)
                     /locus_tag="PC503_001599"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF2527578.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(12220..12475)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12609..13799)
                     /locus_tag="PC503_001600"
     CDS             complement(12609..13799)
                     /locus_tag="PC503_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2527579.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEISRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(14080..15201)
                     /locus_tag="PC503_001601"
     CDS             complement(14080..15201)
                     /locus_tag="PC503_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF2527580.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(15262..15747)
                     /locus_tag="PC503_001602"
     CDS             complement(15262..15747)
                     /locus_tag="PC503_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2527581.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(15749..16417)
                     /locus_tag="PC503_001603"
     CDS             complement(15749..16417)
                     /locus_tag="PC503_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527582.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAVLFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            16807..18831
                     /locus_tag="PC503_001604"
     CDS             16807..18831
                     /locus_tag="PC503_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527583.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(19061..20248)
                     /locus_tag="PC503_001605"
     CDS             complement(19061..20248)
                     /locus_tag="PC503_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF2527584.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(20450..21721)
                     /gene="brnQ"
                     /locus_tag="PC503_001606"
     CDS             complement(20450..21721)
                     /gene="brnQ"
                     /locus_tag="PC503_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2527585.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(21862..22515)
                     /locus_tag="PC503_001607"
     CDS             complement(21862..22515)
                     /locus_tag="PC503_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2527586.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      22844..22945
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23018..24361
                     /locus_tag="PC503_001608"
     CDS             23018..24361
                     /locus_tag="PC503_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2527587.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            24540..25904
                     /locus_tag="PC503_001609"
     CDS             24540..25904
                     /locus_tag="PC503_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2527588.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(26082..27947)
                     /locus_tag="PC503_001610"
     CDS             complement(26082..27947)
                     /locus_tag="PC503_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2527589.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(28183..29400)
                     /locus_tag="PC503_001611"
     CDS             complement(28183..29400)
                     /locus_tag="PC503_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2527590.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(29600..30463)
                     /gene="aroE"
                     /locus_tag="PC503_001612"
     CDS             complement(29600..30463)
                     /gene="aroE"
                     /locus_tag="PC503_001612"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2527591.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(30545..32467)
                     /locus_tag="PC503_001613"
     CDS             complement(30545..32467)
                     /locus_tag="PC503_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2527592.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(32531..33379)
                     /locus_tag="PC503_001614"
     CDS             complement(32531..33379)
                     /locus_tag="PC503_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF2527593.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            33792..34673
                     /locus_tag="PC503_001615"
     CDS             33792..34673
                     /locus_tag="PC503_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2527594.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(34881..35744)
                     /locus_tag="PC503_001616"
     CDS             complement(34881..35744)
                     /locus_tag="PC503_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF2527595.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(35899..37833)
                     /locus_tag="PC503_001617"
     CDS             complement(35899..37833)
                     /locus_tag="PC503_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF2527596.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(37945..38958)
                     /gene="galE"
                     /locus_tag="PC503_001618"
     CDS             complement(37945..38958)
                     /gene="galE"
                     /locus_tag="PC503_001618"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF2527597.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(38982..39851)
                     /gene="galU"
                     /locus_tag="PC503_001619"
     CDS             complement(38982..39851)
                     /gene="galU"
                     /locus_tag="PC503_001619"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2527598.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(40049..40369)
                     /locus_tag="PC503_001620"
     CDS             complement(40049..40369)
                     /locus_tag="PC503_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527599.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(40359..42350)
                     /locus_tag="PC503_001621"
     CDS             complement(40359..42350)
                     /locus_tag="PC503_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527600.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(42473..45016)
                     /locus_tag="PC503_001622"
     CDS             complement(42473..45016)
                     /locus_tag="PC503_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF2527601.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(45294..45628)
                     /gene="rnpB"
                     /locus_tag="PC503_001623"
     ncRNA           complement(45294..45628)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC503_001623"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            45760..46437
                     /gene="srtB"
                     /locus_tag="PC503_001624"
     CDS             45760..46437
                     /gene="srtB"
                     /locus_tag="PC503_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF2527602.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(46597..46671)
                     /locus_tag="PC503_001625"
     tRNA            complement(46597..46671)
                     /locus_tag="PC503_001625"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46637..46639),aa:Thr,seq:tgt)
BASE COUNT        15444 a         8033 c         5110 g        18129 t
ORIGIN      
        1 gtttttatta cattttttat aatacccctt tattttataa attaatctaa tcgattaaat
       61 ttatcctata gaaatttatt acatttaaaa atatgctagc aaataaaata tctactagca
      121 taaagtctat ttataatatt aatcaactat taattctact aaatctccat ttttaacgcc
      181 tgctgcattt ccctcttcca tatcaacatg catttctaga ttaaagctgt cactagctct
      241 tactaataca ttttcaaata ctaatgctct tggtccagat gttttaactt ttactatttg
      301 cttatcagtt acaccaaatt tagcagcatc ttcattgctc atatgtatat gtctagaagc
      361 aactataact ccttctttca tttcaacttc tccagcaggt cctactaatt taacacctgg
      421 agttccagct atatcaccag attcttttat tggtgctttt actcctaatg ggaaaccatc
      481 tgctaaagat atttcaactt gagtatgagc tctagctggt cctagtactc taactccttt
      541 taaagttcct tttggtccta ctaaatccac tttttcttca caggcatatt gccctggttg
      601 agataatggt ttaaatttag ttaactcatg acctgcccca aataatacgt ctatatcagc
      661 ttgactcaaa tgaacatgtt tattagataa tgctattggt aatttcattg aaattccctc
      721 cttttaatta tttaaattat tgcaatacaa ttatacataa tattacctac aaaatcaaat
      781 tatattgaat caatatatat ctttaaattt ttatatatta tatctttaaa ttcttgatta
      841 tctatataag atacatcatc tgtattgttt aaatatatat tgtgtaaaag tttagtattt
      901 atactcttaa agaaaaaatc catcacaatc tgtccacctt taaactgtga atcatatgat
      961 ttactccccc ccactgcaat atacattcct atccgtttct tacttctatc aattgaaggt
     1021 ttatttaata catatttact tgcatatata gcttgagttc tatcaacaac agtctttaat
     1081 ttagctgata ttgaatcaaa atgtacagga cttattacta tagttccttt tgaatcatca
     1141 aacattttat ataatggctt catatcatca ttaaacttgc aataccctgt tttttcacaa
     1201 aatccacatg ctgtgcaata ttcaatatcc atattgtaga tattaaatat tttacaactt
     1261 aatccacact cttctagcat agcttttact tcatttgcta taaaactgca atttttatta
     1321 attcttggac ttccatttat tattataatc tctggacttt taagtccttt tttatcgttt
     1381 gaatccataa tcaatctacc tatcctttaa cataactatt aaaatatcat catcataatt
     1441 atcttttgat gagaagttct ttaaatccaa ttttagattt tctactatta actgttgatt
     1501 taatctaaaa ttttctttta gaaagttttc taatcggttt ataccatact cttcttttga
     1561 tgaatttttt atctctaaaa ttccatcagt gtacatacat accattgcat aatcttccat
     1621 tgaaagagta ttattttcat aagtagcatc ttccattatt ccaataggta tgcccttttt
     1681 acaatttaaa ttattttcta ttgtgccatc tttctttaca actacaggac tatagtgacc
     1741 tgcattagac acagtaatca tattttcttt agtatctata atacctatca aacaagttgt
     1801 aaatactccc atcttgtcaa attcatcata taacatccta tttaaatttg tcattatttc
     1861 tcttggtgta ttgtattgat tgcataatac tttaaaagca ccttttatca ttgcaacaac
     1921 ataatttgat accattccat gtcccattac atcagcaaca atataaacta tatgttcgtc
     1981 atccactttt gtagcataat aaaaatctcc acctactacc cttgctggtt tatggtaaaa
     2041 ataaagttct ttctcatcat tacaatccat tttaccttta tccataataa gctgttgttg
     2101 tttatttaat atgttcaact cgttttcaag aactttgtgt tttacttcct tttcattatg
     2161 ttcatataat tgcataccaa cagaaacttg tttggacaat atactaagaa tatttaaatc
     2221 atcactagta tagtttttgc tatttgcaca aactatacat cctatagtat catttttatc
     2281 ctgaagtttg taatatatat aactttccaa atttattccc ttttttgagc atggttttaa
     2341 attatttaga taccccccca atgactcttt ctttaaaaac atatcaatca taggatataa
     2401 atttgttttc tttttttgct caacattata acaactaact atagcatcct tattatgatg
     2461 actatttata attattaaag cttctttact attagtaata ttacacgctt gtttacttaa
     2521 attttccaaa aagccatcaa tactcttatt aaggtatagt tttttagtag cttcatttat
     2581 ggcacttatt gagcctctta gtttatcaat taaaatttgt acattattat ttttattagt
     2641 tatttctatt gataaactta agagtgatgc aacagatgat ataaaatcta tatcttgttc
     2701 tgttatataa tcatcctctt ttaaaaaaca agtcataaat ccaacaacta cgttatttat
     2761 tataaaagga aaaactattc tcccaatata accttcagct tttgctaaat ctcgttcacc
     2821 ttctgctcta gaatcttcaa atacattttc cacatatatt atcttttttt catttacagc
     2881 ctcatgtata tactctggat atgtgtcaaa atcaattttt gcacctttaa gactatttat
     2941 tggaaaaatt tgaggtacat attctaaggt ttgcgaacat actaagtagg catatttaga
     3001 atcattttta taaaatagat tcacacatgc ctttgtaggg tgaacaactt ctaacatttt
     3061 ttctattatg tcatctttta tattaaaaaa atctgtagat tcagtcacca tagcggatat
     3121 ttccactaaa ttcttcattt tataactgcc attagtcata ctcaatttct ccccctatat
     3181 attaaactat ttattagtat tttaacatac attctttata gtaaaaacaa aaacaacgac
     3241 aaaactagca actaatatcc agttaaatcc tgtcaataat cctataagaa gtaatgtaat
     3301 taatgcattt agacctgttc tccctttttc atccataaaa gttattttag agatgtcgat
     3361 attatttttc acattattta tatgctcttt cacttgttct tccatatttc ttttatatag
     3421 tatataaact acaccaacta aaaacactcc tatacctaaa accatgttta aattaaaagc
     3481 taccataagc aatattgaac caaaagctaa ctttaaaagc ttaaaaaata cactatctat
     3541 ctttagagtt atatttctga tttctttaca ttcatctctt aaagaatatc cacttgaatc
     3601 taagttatta atctttgttt ttacaatttc agaataaaaa agctttatta tcccatttaa
     3661 cattttcatc actcctaaat attttacata tatttgtaag ttttacaatt ataatatttt
     3721 ttatacttgg taataataaa aaataacaaa tattttatta tttagtattt attgtaaata
     3781 agttattgaa gcttgattag ttaagtatag atttttaata aatattttta taatttagaa
     3841 ggaagtggtt ttgtgcaaat agaacaactc gatttagaaa cgagaaataa aatatactgc
     3901 tatactaaaa aaattcttag aaaatatcaa aaaggcataa catctggaaa attaacagca
     3961 gataaatttg cagataatat attgtctcaa gattttatca gtagtatact taatgaaaaa
     4021 atagtcaatg agacaaactt taagatatct tatagaaact atatagaaac tttaataaat
     4081 attcaaaatg aaaatttatc taacttaaga aaaaaatcta ctaaaactgc aaaatgtttc
     4141 aatatctctc aaataaccca attaaaaaac ttactaagta atactggtta taatttatta
     4201 attccatata aatacttaac tgctagagat atagaaggaa tagttactct tattaatact
     4261 gggtctattg aacttggaaa tgagagaatc tacaattata tatcaaaagt ataataattt
     4321 aaacctatta taaaaaggca atttatttaa taaaaaatat ttttaatatt aaataaattg
     4381 cctttttaat tttggattaa atactgctat ccaagtgctt tttctagttt agataaatgt
     4441 tgtattggat aatattttag tagctcttta aattgttcta ctgataaacc ttctgttgtt
     4501 gtatatattc ttattttttc atctaagtca ctattaataa atttgttttt taaatcctca
     4561 aaatttacac tactcatttt acatcactcc ttatgtaaca tattcatttg tattatttta
     4621 tccaaataca taaaatttat tacataaaaa tatatctatt taataattta ataaaaaaaa
     4681 gctatctcaa tttagaaatt actttctata tttgagatag ctctagctaa actaatagcc
     4741 aatagttata aataattatt tataactatc tgttgctttt tccagccatt tgttgttcag
     4801 ccatttcaac taatttttta gtcatgtatc cacctacata accattttct cttgcagtaa
     4861 ggtttccttt atcaacttgt tgataattac tcataccaag ttcattagct atttctaatt
     4921 tcatttggtt taaagcctct tttgctcctg gtactactgt tctgttgttg ttattgttac
     4981 ttgccatgtt gattaccttc cttctgttta atttattttg tgttgctgat aatattatgt
     5041 gattttaaac atttttaatt caggtaattt ttagcaatta aaacctgcca aatatccagt
     5101 agaaaaagct atttgcaaat tgaatccacc tgtatatgca tctatatcta ttacttctcc
     5161 agcaaaaaat aaaccttcta ctaattttga ttccattgta cttgaattta tttcgtttac
     5221 ttttacacca ccagaagtta ttatagcttc ttcaataggt ctgtatctct ttactgtaaa
     5281 ctttaaattt tttaataaat ggactaagtt ttttctctgc tctctagaaa tttggtgaac
     5341 aaccgtattt ggattaattt cacttaagtt tattattata ggtattagtt tttttggaag
     5401 taaatcatct aatgcttttt caaatttttt atttgtatac ttctgaaaat ctttttgaac
     5461 tcttttatcc aatttttcct catctaatgc aggttttaaa tctaataata tagtgtaatt
     5521 ttctttcctt gtatctttca ttctacaact tgcagacttg attataggtc catctaaacc
     5581 aaatttagta aattcaagtt ctccaaaatc actataaact ttcttttgtt tgctattaaa
     5641 cacccttatt tcaacatttc tcaatgataa tttttctaaa tcttttgtaa aactttcttg
     5701 tacttctata ccaattaaag atggttttgt atctataatt gtgtgcccct gtgaaattgc
     5761 aaatttatat ccatcaccag tagaaccagt aagtggataa cttaatccac cagttgctac
     5821 tacaactgaa tcacacttaa tttctttttt atcgtttaaa attacttttt caattttatt
     5881 atttttagat attatttttt ctactttcga atttaataat atatttactt tcttactttt
     5941 aagttgtctt tcaagagcat ttacaatatc aaatgcttta tcactctctg gaaaaaccct
     6001 ttttcctctt tctgttttag tctttactcc aagattatta aacatactta ttacatcatc
     6061 atttgtaaaa gtataaaaag cactataaag aaattttcca tttgtaggta cattttctat
     6121 taattcctct atttcacaag cgttagtaat attacatcta ccttttcctg ttattgcaag
     6181 tttttttcct aatttatgat ttttctcaat taatgttaca tcatagcctt tctcacatgc
     6241 agttgatgcg gctatcatcc ctgctggtcc accacctatt attactacct tcttcaaata
     6301 atcactcttt tctaccctta atttttttaa tttaaactat tgactctata ccttaaaatc
     6361 aatttaattt taaaagttta aataatgctg gagctcctgc tattccataa aaaacaacta
     6421 ctgtattctt aataaaattc ataaaaatta tactcatagt agagtcactt atatttaaag
     6481 tgactattaa cattgaaata aacaacttaa tgccaatata taacattcct attgttacta
     6541 tcccaaccaa aaacctacat attcttgaaa aaattatatt tttactcccc ttatttttat
     6601 tgctaaaatt tatttttttg ttattattat ctgtattaaa tttaacaaat ctatcctcaa
     6661 ccatatatcc aaatacaaat cctactatta taccaaattt ttcaaaatat tcagggctat
     6721 ttagaaatat agccactatt ataaatggta taagtaaaac tacaagtaaa atataatttt
     6781 tattatcatc aatatagtca aatattttta caaatacaac tgtaaaaaat attcctaata
     6841 tccaacccgc tatcacatct attggccaat gaacagctaa atacagccta gacaatccta
     6901 ctcctaaaac cataactgca cctattaaat gaagatatct ctttttaaat atagtcataa
     6961 tactaaccca aaatgttgtt gcagtttgag tatgagcact tggaaaagaa taaccaccag
     7021 cagtagaaac tctcaatgat tcaagacctt ttattcctat tggtctggga gcttttacaa
     7081 actctttgat gcctaaattt acaacaaaat ttccaattat agcaaacagt attttctgtc
     7141 cacatttttt atttatacac cagtatataa ttgttgtaat taatattaat aacggtgctt
     7201 ctgtgcttat tgtaaagaca agaaatataa agttcaaaat tggatttctt aaattttgga
     7261 aaaataataa tatatttaac tgaatatcca tatagatgtc tcctttacta aaattttata
     7321 taattaacta aaaagcacta actcccttag aaattagtgc ttttgattca catttaaatc
     7381 tattctacat cctcaactat acctatataa ggtaaatttc tatacttttc agcatagtct
     7441 attccataac caacaataaa tttgtcttct ataacaaatc caacatagtc tacaggtata
     7501 ttagcttttc ttctctgagg tttatcaagt agagtacata gttttaaaga ttttggattt
     7561 ctagttttta aagctgcaac tagattactt aatgttaaac cagaatctat tatatcctct
     7621 acaatcaaca cattctttcc ttcaatatct acatctaaat cttttaatat tttaactgtt
     7681 ccagaagact ctgttgagtt tccataactt gtaacactca taaaatctat atttacatcc
     7741 aaatctatac atcttattaa atctgaaaca aatacactag ctcctttaag tatacctacc
     7801 actagtaaat cttcgccttt aaagtcttct tctatctttt ttcctaattc ataaactttt
     7861 tcttttattt gttcttctgt caacattttt cctgtaactt tgtacatttt gtatcctccc
     7921 gctttccttc tattaactta tatattatag cataccaaaa tatcaattaa aatctttttc
     7981 atcattttta aacctaaatt aacagcttat ccatactttt ttgcttttta cattaaaaat
     8041 ttggaataac gattcctttg tattataatc tatatgtaca tatattaatc agttattttt
     8101 atcgattata taattttatt tttggaggta cttttatgag cacaaaccat ggagctaatt
     8161 tatatagttt atctagtaag tatggctttt caaaggaaga atttatggat tttagctcaa
     8221 atataaatcc ttttggtaca tcaagtttag ccaaacaata cattgtaaac aatatagata
     8281 tggtatctat gtatcctgac cctgattaca tagacttaaa aacttctata tccaattact
     8341 gcaaatgttc tatagataat atagtacttg gcagtggagc tacagaacta atttcatcat
     8401 ttatacatac aattaaccct aaacaggctc ttttactctc tccagcctat tcagagtatg
     8461 aaaaagagtt atctaaaatt aattgttcta tagaaaaata ctttgcaaaa gaagaagata
     8521 attttcatat aaatttagaa aatcttataa aaactatcaa tgctaaagat tatgatttgg
     8581 tagtaatctg taatcctagt aatccaactg gatttgcatt tactaaagta gaagtgagag
     8641 aaattttaaa aaatacagac tcatttttaa tgattgatga gacttatgta gagtttactg
     8701 atacagatac atactcttgt actcaattag ttgatgatta ttctaattta ttcgttataa
     8761 gaggtacatc aaaatttttt tcaacgcctg gaataaggct tggatatggt cttatatcta
     8821 acactaatgt caaaaatgaa ataaataaaa atctagattt atggaatata aacataatag
     8881 cttctaaaat gggtgaaatc atgtttagtg atttagattt tatatcaaat actatttcct
     8941 taatgaacac tgaaagagat tacctgctta aagagcttaa gaatataaaa agcttagata
     9001 tatacaatac taaaggtaat ttcatattgt gtaaaatcaa gacaaaggaa ttgactgcta
     9061 aatctcttcg agagcaactg cttccacaaa aaataataat aagagattgt tgttcatttg
     9121 aaggtctaga tgagtatttc tttagagtat gtatattaaa acctaatgaa aataaattat
     9181 taatatcatc tcttaaagca atttttaaat aaaaaaatca ctttatttta taatttttta
     9241 taccataaaa aatgagctat ctctatttga gataactcat ttttgattat taaaaaacta
     9301 agcactttgc tcttctttat ttcctttttt actcattcca tcatttattt tatctactac
     9361 tactgctatt gcattatctc ctgatacatt acatgctgta ccaaaactgt cttgagttaa
     9421 gtataaagct atcattaaac ttgcaagccc accatctgat ggtattccaa ccattggtag
     9481 gaaaggaagt gcactcatta tagccccacc tggtgctcct ggtgctgcaa ccattgctat
     9541 acctaacatt gcaatataag ggaataatac acctattcca tgtggcatac cattcatcat
     9601 taaaactgca gttgtaaatc ctgttattga tatcatacta cctgataaat gtattgttgc
     9661 acaaagaggt acaacaaatt ctcttatttg cttacttact ccattttttt ctgcacaacc
     9721 aacattaact ggtatagttg ctgctgaaga ttgagttcct atagctgtta aatatccagg
     9781 tacttgattt tttaacattc ttactggatt ttttcctgaa aatacacctg ctgctgtgaa
     9841 ttgacatgcc atatatacaa aatgtaaagg tattactact aagtatactt tccagaatac
     9901 ccctaatatt gtccatactt cccctgctat agttatattt gcaaaagttc ctgctatgta
     9961 taaaggtaat aaaggtataa tcactgttga caacgttttc gttacgattc cttgaaattc
    10021 ttggaagaaa ttaaataaag tctctccttt tccatgattt cttaaagctg atattccaag
    10081 tcccattaca aatgcaaata cgattgcagc tgttacatct accataggct ctaatggaat
    10141 tgtgaatatt ggagctaaca ttcctgcctc tgggtctcca atttgacttg caacacttgc
    10201 atcaataaaa tttgggaaga ttaatgtaga tactgcaaat gataataatc ctgctattaa
    10261 ggtagaacca tatgctattc ccgtagttat ccccaataac tttcctgcac ctgttgctaa
    10321 atcagctata cctgctgtta caaaacctat aattataaat ggtataacaa attttaggaa
    10381 tgctgagaat aaagtactaa ctgttactaa tatttgtact attatttctg gtgcataact
    10441 tccgattaaa ataccgacta tgataccgat gattagtttg ggcactaaac ctattttttt
    10501 cttcataata tttaccctcc ataacttttt taaattaagc attcttgcac attgaatact
    10561 tagttaaata ttggatatcc acttattatg ataatagagt tttacctctc cgtcaacaat
    10621 ttaaccattt tttgttaata aaaaaaagaa taacatatat aaattgttat tcttcttcat
    10681 cttttataga aaattctaca ttttcaatta tatttgaatg tttatctttt tttgcgataa
    10741 ctctatactt attaatttct tcattcacta tacctatact ccaaattaaa actatagcat
    10801 catctataaa accaaatgcc cctgcaatca tctctggaat tatatcaacc ccagatacaa
    10861 agtaggatat agtaaaaatt aatacagaaa ttacctttat tttatcaact atattgattc
    10921 ttttatctgt cataaaatca ggtagtttaa gtaaatcaaa tacaaaaacc aaaccaaatt
    10981 tagcattttt aaatctgacc aaaatttttt ttaaaatatc taaaactata ttaatgatta
    11041 tttttaaaaa ctccatattt atcacctctt ataattatag gttattctac attataaccg
    11101 atataattaa tttgatgaac atattagata taaattttat caattagttt atatttaaat
    11161 tataataatt caattcctgc actactacaa ttttgaatca tatcctgtgg ccatactcca
    11221 acttgtactt ctcctatatg agctttttgt aagaaataca tacatattct tgactgacca
    11281 attcctccac caattgtata cggaagttcg ccatttaaaa gcatcttatg atagtcaaac
    11341 tcttttctct cttcacatcc agcaagtttc aattgtctat caagagattc ttcatcaact
    11401 ctaattccca ttgaagataa ttctaatgct gaatctaaaa caggattgta aaataatata
    11461 tccccattca attcccaatc atcataatca ggacttcttc catcatgttt ttctcctgat
    11521 attaatgttt ttcctatttg agttataaat actgctttct tctcttttac aattttatct
    11581 tctctttcct ttggtgataa ttctggatac atatcttcta actcttgtga tgttataaaa
    11641 gttatttctt ctggtaatat ttcttttata ccttcataca tactacatac aaaaatttca
    11701 gtatctttaa atactccata caatcttttt acaacatctt ttagagtctt ttcatttcta
    11761 ctacttttat ctataaccaa ttcccaatcc cattggtcta cataaagaga atgtatattg
    11821 tctaattctt cattttttct tattgcattc atatctgtat ataaaccact accaacttca
    11881 aacccatatt ttttaagggc taatcttttc cattttgcaa gtgattgaac aatttctgca
    11941 tttttattca taaatggtat atcaaagctt acagcctttt ctccatttaa attatcattt
    12001 gcacctgttt ctggcaatac aaataacgga gaagaaactc ttataagatt taattcatta
    12061 cttagtctca tttcaaaaaa atcttttaat ttttttatag ctatttgtgt atcaattacg
    12121 ttcaaactac ttttataatc ctttggtatt attgtgctca tatcattcac tccctatatt
    12181 tatatatttt tccattaaaa aaacccttca tccctatata aaagggacga aaggttgctt
    12241 ttccgcggta ccaccctgat tagtttgaaa taaattcaaa cccagctcac aatgtacaga
    12301 tattactcga tacaccccaa tatgataacg gtttggttcc gactaagcct actcttttaa
    12361 aatttcggtt agcaactcca ggatgttctt cactatagac ttcatattgg tctcacacca
    12421 tcaccaactc gctttaatta cattctataa ctactcttcc tttcaaagtc tttaagagtt
    12481 taattcaata aaatttagct ctcttatgtt ttctatttat tcataatagt atgataagtg
    12541 attagttaaa atttgtcaag tttattattt ttttattttt aaacacttta taaattttta
    12601 cctatacttt ataaattttc aaatatagtc tttaatctgt ccatacattc ttttaataaa
    12661 gactgtggac aagctacatt tattctttca aatcctattc cttcttttcc aaatatataa
    12721 ccttcatcaa ataatacatt agctttttta aacattaaat cttcaagttc tacttcattt
    12781 aatccataag cagtaaaatc taaccatgct agatatgttc cttctggata aacaagtttt
    12841 acttttggta ggttttcttt taagtattca tcaataaatt gtatattatt atctaagtaa
    12901 tcatttaatt cattaagcca gtcttcactt tcattatatg ctgctattgt agctacaata
    12961 gcaaagggat ttggtgaagt tgcaactcca acagctgtaa cctcttcttg atatttcttt
    13021 tttagttcat cattattcac tattatatta gacaactgca ttcctgccag attaaatgtt
    13081 ttacttggag ctatacatgt aactatttta tccttgtact ctgggcataa tgactgtaaa
    13141 ggagtatgtt taaatccttt tctaattaaa tcagaatgta tctcatcagc tattatccat
    13201 aggtcatatt ttttacatat ttctacaacc ttttttaatt catcttctct ccaaactctt
    13261 ccaacagggt tgtgaggact acaaagtatt agtactttat tgttgctaca cttagctttt
    13321 tcttctaaat catcataatc catcctataa gtaccattct catatatcag aggattgttt
    13381 acaacgtccc tattattgct ctttatctta gcttcaaatg ggtaatacac tggtttttgg
    13441 actattacac cttcattaga attagttaat attcttacta aaatagcaac agcaggtaca
    13501 acaccaggac taaaaataat atcttttcta cttatttccc agttaaatct ccttttatac
    13561 caatcacaaa ctgcattaaa gtatttatca ctatcatttg aactatatcc aaatatttta
    13621 tgttcaactt ttttacgtaa tgcttctatt attggttctg cacattcaaa atccatatca
    13681 gcaatccaaa aaggcaaacc atctttttgt gcttttgttg aacaattagt tctaaaatcc
    13741 cattttacac aatctgttcc tactctatct attactctgt caaaattata cttactcatt
    13801 ttttccctcc taagaataaa atttttataa ttgttaagtc tattactaga tgcactttgg
    13861 tattatttta caattcttaa tattataata atatcacttt tttgtccaat agatttaaaa
    13921 tataattact tttccatcat attttttcaa tattccaaaa tcagtttcat tatatcaaaa
    13981 taagattgct catattaatt attttctaat taacataagc aatctttttc tataacttct
    14041 ataattataa ttttaaatgt agaattatta gtttggatgt tatcccaatc tcttttcaac
    14101 caatctacac catatatcta caccatattc taaagctttc gtatcaaatg ttacatttgg
    14161 attatgaaat cctggtgtag catcagctcc taatccaata tatgtagttt tacattttag
    14221 tttttgtgta taataatgga agtcttctcc accagaattt ttaaatatac ctatagatgc
    14281 atcagctccc aatacatctt ttatagtttc ttcagccaag tttacaagtt cttcatcaaa
    14341 ttctgctgct ggtactccat ctttggaaat tagtacagct tctgcattta tagaacttac
    14401 aacagttttt acagcatgta ttgctttttc ttttaattct tctattatat cattactttc
    14461 tgcccttata tctaaagcca taaatgcttc atctggtata ttattataag tttctccctt
    14521 aactgatata tttgttactt ttatagaatt tggtatagct ggatttactc ttattgcatt
    14581 tattgcattc actgctaaac agacagcatc tactgcattt actcctaaat gtggtttaga
    14641 accatgacaa gtgatacctt taatcgtaaa ttccattata cagctagcac aatggtacat
    14701 tgcaggtatc gcctttccca acctacaatc ttgtccaggt cttaaatgca tccctaccat
    14761 ttcttctaca tcatccaaca aaccagaatc aattactctt aatgctccat ataatttttc
    14821 ttcacctggt tgaaaaagta tttttaactt acctcttttt actaaatttc tctcttttat
    14881 taactttgca gctgttaaaa gcatagaagt atgaccatca tgaccacaag catgtatcat
    14941 tttcttttct ccatctatga taaattccaa tgcatccata tctgctctta tagcaaatac
    15001 tggtccttct tttttagaat ctatagttac tataatacca gttcctgcaa ctcctttatt
    15061 aatattttca aaccccattt tttcaagctc ttttaaaaca aactctgatg tcttatattc
    15121 ttcaaatcct ttttctggta tagtgtgtag ataatcatac actttatgta catactcaat
    15181 ataatctttg ttagttccca taatctagct cctccttaaa atttaaactt tccatttata
    15241 ttaaattttt attataatta cctatactac gaaataattc attataagca ttgcaataca
    15301 accatttaaa gttgctataa caaacatatg tggataatat ttagttttta actcagctgt
    15361 tcctaaaagt ctccccataa attgtatctg cgctcctgaa agcaataaca ttggcaatag
    15421 aattgcaaca tgtgcttgac ttatttgacc tgctgtaaat aaacctgcga ttactccaga
    15481 tgctcctccc attgatataa atattgtcat tatagctgtt gctgcaacac ctggaagtcc
    15541 aaagatactc attacaggtg taaatattgt ccctattaca tccaaaagac ctgttaagtt
    15601 gaacacagaa attatagcaa aaccgaagat gacatttgga gccattgaat ttgtacttat
    15661 ttggaatcca tttctagctc ctccaataaa cgcatctatc acatttcctt ttttaacttt
    15721 tacttctttt tttgctacct cactcatgtt aagcttcccc cttgtcaaat ttatttaaat
    15781 ataatctaag taagttcgcc ccaacaaact tcataattaa tattaaagca agtggtataa
    15841 atattggtac atctcctata aatggaaata gtactgctcc agaagcaaag aaattcgtaa
    15901 ttgcagacgc acctgaaaat tgaaatgcac aaaatacagc tttttgtttt tcatctatat
    15961 acccatcatc tttaagttct ttagtcatag atgcagctgc atctgtagac tgtaaactag
    16021 ctatcaaagt tagtcctgca aatccaggta accctaataa tggctttaat agtggactaa
    16081 gaagcttttg agctgccttc attccatcta agtggtctat aactctaact actccaagtg
    16141 caaacataac tgatggtatt aatgtcaatg catatagcca tccatctcga gggccagtac
    16201 ctccatcacc tctaaagttt gcagctaatg tacctacacc atcattaatt gttcccaatg
    16261 ttccaaaaga acctaataca ttgttaaaat ccaatacttt taatggtcct ggtgcatctt
    16321 taaatattcc tgaaaaaaat aatgctccca atattaatgc tacataccca taccatttta
    16381 cctcaacttt ttctgttgtt gattctaatt tactcatata aattctccct cctgtttaaa
    16441 tgaattttat tagtatactt gtttaataag caaaacttat gccaatacct taatgataaa
    16501 gcctttgtat ttattttttt attgtaaatt tattccagtg attaaatagc ttataattac
    16561 ttacttttca agtttaaaaa tataatattt ttttattaat tatttaaaat atacattaca
    16621 atataaaaag ctattttcct tatcttgcaa aaataatttc aaaataggtt tttataggat
    16681 aaaatcctaa aaaaacctat tatttaatca aatatataaa tttatactac tatttgttgt
    16741 ataatataac ttgccttata ctttaaatac tttaaaaata aatactattt tgttaggaga
    16801 aataaaatgg ataaaaagaa gttaatcctt ataacatatg ataaattgaa tagtgaccac
    16861 tacaaagaag aattaacaaa cttttttgga gacgaaataa tcatagaaac acaaaatata
    16921 cttgatggaa taaaagaaaa tttagaggga gatgtagtgc tttctctatc acctttaact
    16981 agtaattttt taataaaaca ttttaaggaa gatattgaaa ttattcatgg aacgaaagca
    17041 ctttcaaaac ttggatatga aaaaatgatg aaactgcctc caggtacaaa atcgttactt
    17101 atgacaacca ataaaacttc agcatttgag atggctactt atctatataa aattggtata
    17161 aatcatatag attttgtacc gacatatcca gattgtgatg aaatatatga tttagataca
    17221 gctataacac caggtcagat tagatttata ccaaaataca taaaaaatat tgttgattta
    17281 ggttggagaa aaatctcatt agatacatat atgtcattat tagtagtatt aaaactaaaa
    17341 aatgagaaat ttatagaaaa attatacaaa ttgtccaagg agacactaag tcatgatttc
    17401 ttaaatacat cattagataa tatatctaaa ttaaaaacta tactttacat gaccattgat
    17461 gaaataggtg atggtctaat atttttcaat acctttaata aggttacttt tgtaaataag
    17521 tctttactta atatgttgga actagatgaa aaacttataa aatcaccttc cttaatggaa
    17581 tatatgccaa agagtttctt agataaaatt acaaagaact taaatataga taatatgatt
    17641 atatacatag acgaaataga taaaaaattc atactttcta aaaaaccatt ttatctttat
    17701 aaaaatatag agggttgctt aattacatta aaagatgtaa acaatataga aatattagaa
    17761 caaaaaataa gaagtgattc tgtcaaaaga ggttatgtag ctaaatataa atttaataat
    17821 attattggaa atagttctat tataaaagat tgtattaaaa aggcaaaaaa aatggctctt
    17881 acagataatc ctatattaat aacaggtgaa acaggaacag gtaaagaagc ctttactcag
    17941 tcaatacaca atcattcaaa tagaaaaaat aaaccttttg tagcaataaa ttgtgcttca
    18001 ttaccaagtg aattacttga aagtgaacta tttggatatg aagatggttc ttttactgga
    18061 gcaaaaaaag gtggaaaaaa aggattattc gaattagctc atactggcac tatattttta
    18121 gatgagatag gagatatgcc acatgattta caggttaaac ttttaagagt cttacaagaa
    18181 aaagaaatta gaaaaattgg tggtacaagt attattccaa ttgatgtgag aatattagct
    18241 gccacaaata aagatttaga gaaattaatt atagaaaata aatttaggat ggatttattt
    18301 tataggataa gtatgttcac tttagattta cctcctctta gaaagagatt agaagatata
    18361 cctcttcttt tagaatcatt tttaaaagaa cttccctata aaaacataaa actcgataag
    18421 agtcttttag aagctttaaa ttcatacact tggatgggga atattagaga actgagaaat
    18481 tgtgttgaat atatggctta catgggttcc aattatctta caataaatga tttacctcaa
    18541 aacatatctt caaaattaaa taataatcat atgtcaagta atatgtccat attcaatgat
    18601 ttaaaccaat atgacaaaaa catatgcatt tctatcctaa aatcattgca catgaaacca
    18661 atggggagga caaagttaat gaaatttatg gaatataatg tcacagaata cgaagtaaga
    18721 aatatgctag aatatttgac acgcaatgga tacttaattt ctagtaaggg aagaaaaggc
    18781 tcatcaataa ctgagaaagg cataaaaata atagaaaata atataattta aacctatagt
    18841 aattcatctt tactttatca aaatttatat ataattataa ttttttattt ttctataaat
    18901 tttttataaa ataataaaac ttatttatat taaaaacgaa gctatctcaa catatggata
    18961 agcttctttt taattgttaa aaagataaaa atatatttga tttaacagaa aaagagtgcc
    19021 tcataaacta aaaagttcat tttgagacac gtccttaata ttaataaatt aattggctta
    19081 aaattactga ttgataatta taaagtacct ctgttaaagg agtaaattct gaaccgattc
    19141 caaatcttaa ttctgtaaac gcctctaaat aatctgggtc acatacatct tcttgtgtta
    19201 aatcttgttt caccatttca gtagcaagat aaattgctac tgatggtaga aaagcatcca
    19261 ttggcatagg atatccacca agtctatttg acatgccaaa agccttagcc ttttcactta
    19321 tcatgtcgtt tattttatca taattttgag catctttttc agatattttt agacccataa
    19381 cactaggata tgtttgtatt ggtgatggat tgctttgctc tgcaactata tactttaatt
    19441 ctaaagcctt agtcaatata acttcatcca tatactcatt tacaccaaat acatttatat
    19501 cttttccata ttttttaact tgtttttcaa tatcttcatt taaaaactgc ttaactttgt
    19561 ttttgtcttc ttcagtattt atatttggag tattaacttg tacaaatggc aatcctatat
    19621 ttttgcaagt ctctttaatc atttctaatc ttttggctat attaacatct ttcaaatcat
    19681 ctgtagaggc ataatgaata aaagcttttg ctcccatttc ttttgaacgt tcagctaata
    19741 cttttcctct ttcctctgca ctaaccccta gattcacatc aacaaattgg cttaattggt
    19801 ttttatcatc tcccataggg gcagaaatag ttattatttc tggacgcttt tcctttacct
    19861 tttgtaaagc aggtaaaagc cctgcttggt cagttgaaac tacaatagcc tgaacttctt
    19921 tatcgtcagc caactttact atcttattaa tagcactgtc tatattagaa gtaaaattct
    19981 ctggcaatac aacatgcttt atagtttgtt taactttagt ttgaccatct ttgtctttat
    20041 caattttatt ctcttcctca tattcttttg ccatctcttc caccatattg tattgtactt
    20101 tattttcaga taatggttga gttaccactg caactttaaa atcatctata attttctctt
    20161 tatctttctt gcctacaagt aaactacaac ctgtaagtcc aataattaaa catatggata
    20221 gcataaatgc tgttattttt ctaagcatta attaaaacct cctaaatttg tacattctta
    20281 tcactattac taattttatc atacttcaaa gaaaaattat attataaaaa attatataca
    20341 tgctattata atccaatcta aaaagtacta tgggtagatt aggtttagat taaacctacc
    20401 catagtacta aaaattaata tattataaaa ttaaattaat tacaaattat tatgctactt
    20461 gtttgttgct ttttataaag ttaccaacta ttccacccaa tatagctggt attacccagt
    20521 taaagcccaa acctgcaagt ggcaagcttt gtataaatgg aacagctcct gtcattccat
    20581 ttatagctga taataaacta atcactaatg taacatatgc tgcaccttta aaagcattat
    20641 cattctttat atgtttacca gccaactcca taacaactat tgctaataaa acaggatata
    20701 tagtttgtag gattggaact gatatggcta ttatagaatc aacacctaaa tttgatataa
    20761 gcatactagc tacacatata cctataacca gttgtttata actcgcctta cttattcctt
    20821 caaaataagt tgatattgat gctgttaaac ctgtagaagt agtcagacag gcaagtgcca
    20881 caattacacc taaaattacc tttcctactt gaccatataa caatatacta gttatttcaa
    20941 ctaataaaga tgcttgaggt atactagtat catataaagt tgaaactgtt gcacctaaat
    21001 aagtaagacc accatatact actgctagaa atacacaggc tacaaaacca gctttaatag
    21061 tcattcctat ttggtcttta tctgatgtat atcctttagc tattatagac atcaacatta
    21121 tagttgccat agatgctgca cctagagcgt ccattgtttg ataaccttgt gatatacctt
    21181 caccaaatag atttttatct atcatatgct caggactcat aggtcctgct ggagaaatta
    21241 taccctttac tattaaaaca aataatacta ataataacgc tggagttaaa tacttaccta
    21301 ttatgtctat aaccttagaa gacctaatag taaatgctaa agttagccca aagaagatta
    21361 ttgaaaatac agctttagct actggaccat ggtctccaaa tataggcata atacccattt
    21421 catatgttgt tgcgcaagtt cttggtatta caagaagtgc taaacatgct agagcagcta
    21481 cactcattac tcttgctaac cctttaccag ctctcctaag tacatcatcc atgcttccct
    21541 tacatcttgc tgttgctata ataacaagca ttgctatacc agcatctgca acaacaaatc
    21601 caataagagg aattaaccag tctttgccgg attccatccc taaaaatgga ggaaacataa
    21661 gatttcctgc accaaagaac atagaaaata aagcaaaacc aactataaaa atatctctca
    21721 tctgcttact cacactaaat tacccccttt gaaaatattt tgaatattaa gataatctta
    21781 ctttattttc agaaaaatgt caatctggta aaaattcaca cattgttaac gttttcccaa
    21841 tttattttat gaatattttt ttcattttat gataattccc atcaatttcg ttaaatcaat
    21901 tgcttgtgac acatcaaaaa ttgctcctct aatatcatct ataccaatct caattccctc
    21961 aatattatta gtagtaaaat ctatgccaga aagtttagtt ccattaaagt ttgctttttt
    22021 taaatttgta tactcaaata ctagattgtc accttttact tcttgaaata cagaattttc
    22081 aaaatttgaa tctaagatag aaactatctt aaatttagag aatgaaaagt tagaatactt
    22141 acctaaaaca tccttgaaca aaacgttttt aagtatacaa tcatcaaatc taactcctat
    22201 caatttacta tttttaaatt caactctgta tatacttcct ccatcaaaaa atgtatttga
    22261 taaattgcag ttttcaaata ccacatcaag taaatcaatc ttttttaaat tacaattttc
    22321 aaaagacaca tttctaaata tacaagattc aaagctaact cttacagaat ctaaatcact
    22381 tataacttca ttttctataa ttttattaaa tattttttca tcattaaata tatcttcaag
    22441 tatatcttca agattttcaa taatttctaa ttctcctgta aatttaggtt tttgcacttt
    22501 aataatttta gtcattttcc cctccactat aaattatatt atttttgata ttattttttt
    22561 taatatatta acttaatata catatttgat atattaaaaa gtttttacga aatatccatg
    22621 tattcagtac ttttataatt atatcacaaa ctcatttata ataaacttcc attaatagta
    22681 taaaacaagt tagaataatt gacattatac tcatacatat tcaattattg gaaaaagtaa
    22741 tttttttcaa taaataacct taatttttta taaaatcgac aaaaaaacga ataattttat
    22801 tatatttatt gtaaataata caatattacg atataataca acagaaaaac aaatagaaaa
    22861 tgttcatata atattagtaa tacggtctaa tagtttctac aaactcacct taaatgggtt
    22921 ttctatgaat agaatgtcaa ctctgaatat atgttctatt ctatctatat gaatatatat
    22981 ttttttgttt atatcttaaa gttttttgga ggtaaaaatg gtaccaaaca ctaacaatgt
    23041 acaaccaggt ggaaataatt catcattaag ctttttagac aaaatgttta aatttagcga
    23101 acgtggctct agccttaaaa cagaagtaat aggtggagtt actacattct taacaatggc
    23161 atacatagtt ttcgtaaatc cagcaatatt atctgaagct ggaatggata aagccgccct
    23221 tataacagtt accatactag ctacagccat tggtacactt atatttgcga ttttaggaaa
    23281 tgcaccattt gctctagctc ctggtatggg attaaatgca tttttcacat actctttggt
    23341 tataggtgca ggaatcccat ggcaaacagg tcttggggta gtttttctat ctggatgtgt
    23401 cttctttaca ctcgcagtaa caggtcttcg aaagacaatt gcagacgcaa ttcctagaga
    23461 attggcagta gcatcttcag caggtatagg tcttttcctt gcttttgttg gtttaaaaaa
    23521 tatgggtgtt ataatagcta atccagatac tatagtttca cttgcagatt ttacaccaac
    23581 agttttaata gccctttttg ctcttatctt aatggcaata ctagaatata aaaaagttaa
    23641 aggtggaata ttgataagta tagtagttgc aacaataata tctgttatat ttggatttgt
    23701 ggagttgcca acagcaataa tctcaacacc tcctagtata gcaccagttg cttttaaatt
    23761 agatattgta ggtgcattga aattctcatt aattggacct atattctctt tcatgtttat
    23821 agacatgttt gattcattag catttcttat tacttgttgt aaacaaatgg gtcttgaaga
    23881 tgagaatggt gaaataaaag atttaggaag aatgttatat gcagatgttt cttctacttt
    23941 aataggctca ttcttaggaa ctagtactgt tacaacattt ggagaatctg cttctggtat
    24001 tgcagcaggt gcaagaacag gacttgcttc aatagtaaca gcagcattat tcttagctac
    24061 acttatattt acaccattac ttggtatagt tcctacttac gctgcagctc ctgcacttgt
    24121 aatggttggt gtgtttatgt ttgaaagcat aaaacagatt gattttgctg atagcaaaat
    24181 agctgtacct gcttttgtta cagttttatt gatgccttta acttatagta taagtattgg
    24241 tttatgcttt ggatttattt catatataat aatgcatgta gtagctaaag aaactgataa
    24301 aatcagtatt acactttgga ttataggttt acttgcagtt gtaaacttag ttctaagtta
    24361 atatttttaa atagttctag gtcaatattt taaattatat agaataaaat cttatttatt
    24421 ttaaatttat aaatagcaaa atcactttat atgtaaattg attttgctat taactttgta
    24481 tagaaaattt attatcataa tatatagata taaaaatata tagaaaagga gtggtgttta
    24541 tgtcacaatt acttataaaa aatgcatatc taattactat gaatgcagat agagaggtat
    24601 atgaaaatgg aagcatactt attgaaaata atattataaa agaggttggt aagtttgata
    24661 ttaatattgt agataaagat gcagagatat atgatgctaa aggaaaaata ctaatgccag
    24721 ggctagtcaa tactcatgtt cacttatctc aacaattagg acgtggtctt gcagatgatg
    24781 ttgtactttt aacttggctt agagaaagaa tttggccata cgaaagtagc ttcaattatg
    24841 aagattcctt gatttcatct actgcatgtt gtgttgaatt gataaaatct ggtgtcacta
    24901 catttttaga atctggtggt caatatgtag atgctatggt tgaagctgtt gataaaactg
    24961 gacttagagc ctgtttagct aaatcagtta tggatacagg agatggtctt cctgaggcat
    25021 ggcaaaaaac tactgatgag gaaatcaaca ctcaattaga cttattccat aagtttaata
    25081 atacatctaa tgagagaatt aaaatatggt ttgcattaag aactattttt aatacaactg
    25141 aagaattact tgttagaact aaagaactag ctgataaata caatacaggt atacatatgc
    25201 atattgctga aatagctgat gaaatttcat ttgtaaagca aaacaatgga gttggaacag
    25261 ttgaatacct tgataaacta ggtgtattag gaccaaatct tttagctgct catacagttt
    25321 ggcttactca taaggaaatt gatttattta gattacatga tgtaaaagtt tctcatgacc
    25381 caggttcagc tatgaaagtg gttctagggt ttgcatcaat tcctgaaatg ttagaaaaag
    25441 gaatacctgt ttcaattggt actgatggag ctccttcaaa taatagaatg gaccttatga
    25501 gggacatgta tcttacatca ctaatacata aaggaagaac tttaaaccca actgtcgtac
    25561 cagctgaaga agtcttagaa atggctacta taaatggagc aaaatgtgct ttactagaaa
    25621 aagaaattgg tagtcttgaa gtaggaaaaa aagctgatat gattattcta aatccagata
    25681 caattcattg tttaccaatg cataatccaa ttggaaatat agtttattct atgactagtg
    25741 aaaatgtaga ctctactatt tgtgatggta aatggttgat gaaggaaaga aaagtattag
    25801 ttgtagatga atctgaatta ttaaataaag ttaaaaaaca agcttctaaa ataaaagata
    25861 aagcagaagt taaaattcca tctaaattta aaattataaa ataacataaa tttcaattgt
    25921 tttgtaaata tgaatatata aatatattta tatacatcat atatacaaaa caattgtttt
    25981 tttattttat attcattagc attgctcata aaatacacca taattccaga aaaaataacc
    26041 aatcagttag gattacatca tctaagcaat atataaacgt cttagtttat aagttttatt
    26101 ctactcttat ctaaaaccat ctttaaagag ttttcaactg tttcaattac atctttataa
    26161 ctcaagtaca catttgcgta gatacaatct tcatataaat tatattcagt tactctacaa
    26221 tacagcagtt ttcctccatc taataaattg ctcaaaatat agttttcttt tcttgggaca
    26281 tagcctatca catatccagt ttcaccaact attttaatag ctttttcatc atatagatta
    26341 tctttctctc tagttaaata gtatatctta cttttctcca attctttttc aagatattct
    26401 ctatttctaa accttgaacc agcaacagct attgaagtca aatagatatc cttaccatgt
    26461 tcatctactt ttattttttc aatatttaca aattcttttt ttaaattatt actttcatat
    26521 aatactcttc ttaattcatc cttcaatata acattttttt ctttttcata cgcttcttta
    26581 acaattttta attcttcaag agatagtttc tctctgtatc tttttaagat atttatggat
    26641 tcttttctta cttcatttat atttccaaat attcctttta aagatatatt ctttccttca
    26701 ggatatagtg atttacttcc tttaagcaca ataaaaaata acatatcatc ataatattct
    26761 tgagtcaatt tatctttttc tatatctttc atttttccaa ttaaatcatc tattttaaac
    26821 gtctcttcaa aaaaatttaa taattttaat ctagaacttg tcgttccctt tttagatata
    26881 tgccaatata cctcaaaatc tctaatatct ctatttagat atggcaacaa gtcatcaaaa
    26941 gataagttta catcataaat ttctgacatt tttataatat cttctgtttt tccactagca
    27001 tctcttaatg cttcaaaata tatatttttc catttttcac tgagcaagat accatttatt
    27061 tctttttcaa attcaatctt attgcactct atattttcat cttttaagac gtttatagct
    27121 attaggaaaa ttgaatataa actttcaaag ttagtcccat aatttactac agtaggtaaa
    27181 aatcgattca ctaattctaa tttattacct atatatttaa attctacact tagcaagtaa
    27241 ttgcatataa gacgtgctaa attatttatc ttttctttat ctaaatctcg tttttcaaga
    27301 tattcattca aatctacaat tgaaataata tagttcatca ataatcgttc gtactttgta
    27361 tccttataac catcttcaat tagataggaa tttattttag aatctaaatt ttccatatta
    27421 acaatagcaa atacttttat tgaacctgta gcctttttag ataaattaaa taaatatgta
    27481 ttgtaaaatt caagtttttt aatagtatta ctcagataaa atacgtattc tccagattta
    27541 gaaaatgtat ctacaacttc tcttaagttt tctacattta gatatttctc acttaaaact
    27601 aaccctagtt ttacatactc aactttttta ctcttatata ttaattcttt agttaattta
    27661 tataaccatt tctcatcaat aatcatttct tttaccaaag tatttatctt tttcataaaa
    27721 atttcgaaat aacaaattaa agacttagaa ttactaccct ccaataaata aatttcatta
    27781 gattcacttt tatacatatt taaaatttca tctactagat tatttgcaag ctctacttgt
    27841 tctcttaacg gtatactttc atatatacat aggtaattca tttcaaatga ttctttgtat
    27901 ccatcataac cattaaattc ctgcaatcgc ttaaaaacat tctccaccaa attatcctcc
    27961 tttacatgat gtaatttata ttgattatac tacttatttc atcaagttta catttatacg
    28021 caaaaaaata ttactagaaa ttgaaattct agtaatatcc ttattattaa ttatgtaaat
    28081 accctatctt ataactgtaa ataatatcct tattaatttt aattactttt aataaaaatc
    28141 tatcctagat ttagacttct ctatgcatat attatactaa tattagacat cataatcata
    28201 cactttttct ttttcatatc tcatgtttac aaacaatgca agtaaaattc caacaaatgt
    28261 tattgccaca ttaaacaata caacatattt tggtccatta actccccctg attttgtaat
    28321 aatacctgct atatttaaaa taacatagtt tgctatacta gatgcaatca taactataga
    28381 tgttattttt cctttattag ttggaaacat ttcatttgca gttgacgttg ttaactgaag
    28441 aacacctcct gctgctgaat aacctattac aaatccccct aacatacaaa tagttggagt
    28501 ttgaacaaaa tatacaacta atagcataag taaagctatt ataggatata taactaatat
    28561 tcttattggt ttaatatatt ttttaataag taaagaagtt attaatactg cacatattac
    28621 tcccattgag taaaaggatt gaatttttgt agggtcagcc atcccataca atttacccaa
    28681 ttcctgatta caatttaacc ataatacaaa tgtagatgta catgtaaatc caatacaaac
    28741 aagagctata cttgttggtg taaatttcat cttctctgat ttaactgttt tgcctttgtt
    28801 atcaataaca ttattagctg gtggaaatgg taacacagct atcaaaaagg catctactac
    28861 aataagaatc gctgttacta taaaaataac tttaaatgat attgaatttg ctgcaacaaa
    28921 tccaattata aaaggaagca aaaattgtgc taaagctatt gtaaatttag taaacatatt
    28981 tgctattgtt cctaaactag caaatatctc catacaagaa ggagttacac aggtatctaa
    29041 gaatgaattt gctgcccctc caattattgc aaatacatat gctatataaa aatttggtga
    29101 aaatacaatt ccaacaaaga aaattgcatg tagaaagttt cctataagac cacttacttt
    29161 tcttccatac ttatctgaaa taggtcctgc aaatggataa gatataagtc tccctaatcc
    29221 tagtgcagca ataacagcta aaacaatact tacatccaat gttccatctg ataatgtttt
    29281 agccccccac attgatgaaa attctggttt gtattgtcct aaaattgaaa ttccaatacc
    29341 aagtaaaaaa tatgaaaaat acaacgctat ggcagtagga taatattttt tattgttcat
    29401 aatttttctc ccattcttgt taatttatta acatttttgt gtacaataaa ctcatcccca
    29461 taatggattt aaagtatagt cagttaaagc ttcaaattta actggactat gaggcaaaac
    29521 ccactatgac aatttgtaat ttattattaa aaatattgaa atacgtatgt tttttcattg
    29581 tttaagatat tactcttatc tatttaaagc ataattcatt aacttcttct acaggcattt
    29641 ctaatccagt atatagatta aaagcttctg ctccttggta taataacatt cctaatccac
    29701 caatagcctt acatccatta gcttcagcat cttcaatcat ttttgttttc ttaggattat
    29761 aaacgacatc tgttactact aaatcttttc ttaaaacact agtatctttt atatttgttt
    29821 cattgtcata aggcttcata ccaataagag ttgcatttgt caatatatca cttgattgta
    29881 tctcctcata aagtttgttt gtatcttcta aatcatatag attaacaaca cattctggta
    29941 catctttttt tatattctca actgtttgct ctgctctttt ataaaaatca tccttaggat
    30001 taaagataga tatttctctt gctccatcta aagcacattg tacttgtata gcagttgctg
    30061 caccaccagc acccataatt gtaatctttt tacctttaac ttctacccca ttttctttta
    30121 aattacgaac atagcctact ccatctgtta tatgaccaac taactttcca ttgtcattta
    30181 caattgtatt acatgctcca attatacgag ctgctggaga aagttcatcc atatattctg
    30241 taacagcaga tttacatggc atagtaacat tggctccttt tatattaaaa gtttttattg
    30301 ctaaaagtgc ctcttttacc ttatctactg tgatatcaaa ggctaaatat ctataatcta
    30361 aatctaattt cttaaaacta taattataca tcactggtga tttagagtga ccaaccggtg
    30421 tacctattaa tgcaaataat cctgttctac ctgaaatttc cataactata atctcctctc
    30481 aatattatca ttttctttgc aaataaccta ttcagttatt tacaaagaaa aatttattta
    30541 ttatttatat atttaatgct acttcaaaag cttcttttgt tgcatctaat gccctacgag
    30601 cttttactgc atcaccaaca atataagttt cttttacaac ttcttttata acttcactta
    30661 atgggtcgta attacgagaa cccatagcaa gtactactga atcaaaacct tttaaatcat
    30721 gctctgtgcc atctgtaagt aaatagtcga caccatcatc ataaaattta gaaacttttg
    30781 caccagtaat ggtatgtata ttataatttt caaaatcatt cataaggaat ttacggtgtt
    30841 ctgaaattac atctgcacca acttcttctc taagctcaat aacagtaacc tcatgttctt
    30901 gttctccaag gaaggctgcc acttcacatc caaccattcc acctccaaca acaagtactt
    30961 ttttcccaca agatttttta ccatcaagaa ggtctacagc atgaattaat cctgaatcat
    31021 tgattcctgg tataggaagt acaagtggag ttgctccagt agctataata actacatcag
    31081 gtgatttctc ctttataagt tctactgtag cttctgtatt agtacatatt tttacaccat
    31141 attgattaca ttttgaaata taacttctaa ctaagttagt aatatctcct ttccctggag
    31201 gatatgcagc taaacgcatt tgcccaccaa gaacttcaga tttttcaact aaagttacat
    31261 tatgtcctct tttagcacat acccatgctg caagcatacc tccaacacct ccaccaacaa
    31321 caagaacttc tttgctaatt tcagctggct taagctctgc ttcatgtcct aatataggat
    31381 ttgcaagaca ggctataggt ttgccttgga acatatttgg tacacatcct tgtaagcatg
    31441 caatacatgg tatcatttcg tctagttttc catttttagc tttattaggc atttctgggt
    31501 cagccaagct ttgtctaccg aatgctacta aatcacatct tccttgtctg accattaact
    31561 cagcaaactg tggctctgta taacgtccaa ctgttattac tggtatacta acagcttttt
    31621 ttatttcagt aactaattct gcactgaatc cagcatgtaa agtcgtagga gcccacatat
    31681 attcatcatg tatatgtata ctacgtgaaa catgaagtcc atctattcca caatcttcta
    31741 gatatgctgc tattactgaa ctatcgtgta catcaattcc tcctggaaca tcatcagtgc
    31801 tgtttatacg acataatatt gctagagaat ttcctacttt tttacgtata ttttcaatga
    31861 taagacgagg taatctcatt ctattttcaa aacatccacc aaactcatct acacgcttat
    31921 ttgttctttg tgatataaaa ctactaacca gatatccatg agcgcagtga acttcaacag
    31981 catctgcacc agctttttgt gcacgtaatg cagcatctcc ataagattct ataagttcat
    32041 atatttcttc tgttgttatt gctagtggtg tattacgacc atttgatgca ggtattgcag
    32101 aagcagcttt taatggatgt cctgctactt tttcatttcc ttcagaacca gcatgttgta
    32161 attgtataga taccttcgaa cctgcatcat gacaagcatc tattacattt ttaaaactat
    32221 ctattgtgct atcatcatat aaacaaggct tacgaggacc tccttttgct tttttgtcta
    32281 caacactaga ttctatagtt attaatccaa aaccacctaa agcacgctca agataataag
    32341 ccttagaagt ttcacttaaa gtaccatctg tgtttgcaaa attgtttccc atagggggaa
    32401 ctacaaaacg atttggaact gtcattgaac caattcttat aggtgtaaac atagaactaa
    32461 tcttcataag gttttccttc ctttcaagtt ttatattata atactctgta tatttttata
    32521 ttatataagt ttattttgga gatacttcag accatgcttt atccaaaact tttttagttg
    32581 cattaaatac agtttcagca gcagtggata accctttaga tattagagaa tcagatatta
    32641 cttctgcccc tatgactctt ggtgatatat tgtgttcttt tattattttc acaaattcct
    32701 ctgtgtttcc atatccttca cctggagcca aacggtcatg tagtgattca tccctaagtt
    32761 tttcataagg agtttctaaa acatcacaca cttgaattga tactatctta tctgctggaa
    32821 caggtgcaag gtcctctgct gtctgctttg ctctagccca gtgccaagta tctaatataa
    32881 gcattgcatt ttcacgatta catcctttca caacacgcca tgcagtagcc aaatctggta
    32941 caccactata tggcataaac tcaagaccta taataagttc acctgctctg tcacataatt
    33001 ctcccaatgc agttataatt tgttcttctg gtatcatctc taataatcca caatttatat
    33061 gtttaacatt aaataagtga gccatatgat aaacattttg ctctttttct ctttgagctt
    33121 ccgttctatc ttcttctctt ccccattgag ttatatattc tacttctgta actttcatat
    33181 catattcatt aagaattgca atcatttctt catctgtaac acctgcattt tttgcatcaa
    33241 tataattttc agcacgcaat ccaataccat caaacccagc ttcttttgca atacgaactc
    33301 tatcacggaa tgaaacttct gttcccaatg tataagaact aattgtaatt ggaatattaa
    33361 gatttttttg attattcata gcttaaattt gcccccttta ttttctttat aattaatagt
    33421 atttttgatt ttatattttt atttatccta ctagtagtat tattttacct taaaaataaa
    33481 agtatttttt gatttctatt tatctagatt ttataaattt attgtatcac gagactttac
    33541 taataacaaa ttgataattt cctattaatt catagatttt gtttatagat tttatttata
    33601 agataattct tgtatttttc tattaggtcg tataaatata tttatcttat aattcagaca
    33661 aaaaacgata aattttttta aaagctttta ttcttactct ataatcatat ataataaaaa
    33721 tgtaaaaata tcttaaaggt taacttctac aaatatataa ataaaaatac ctatgaaagg
    33781 atgaacaaaa attgaattta tatcacttac gctattttgt tacattggca catttagaac
    33841 actatacaaa agcggcagaa aatttatcta taacacaacc aagcttaagt catgctattt
    33901 ctttactaga aaatgaactt ggggtggctc tatttgaaaa agaaggtaga aatatagtcc
    33961 ttactaagta tggaaaaata tttttaaaag atgtggaaaa atcattagaa attttagatt
    34021 caagtgtaaa atcattaaaa ataactggta ctggtgaagg acaaatagac ttagcttttc
    34081 ttagaacact tggtactgat tttatcccag acatagtgca caaattttta aaatctaatc
    34141 ctgctaaatc aatagatttt aaatttcata ctggtgtaac tactgacatt attcaaggtc
    34201 ttaaagaaag aaaatatgat attgcatttt gttcgaaact tgaaaaagaa aagggaattg
    34261 aatttatacc tgttgccaaa caagatttag tactaattgt accatatagt catccactag
    34321 ctgcaaagga tactatagat ttaaaagaaa ccatacctta tcctcaaata gtatttaatc
    34381 agagaagtgg tcttagatat ataattgatg atatgtttaa aaaaataaat caacagccta
    34441 atatagtcta tgaagtagag gaagaccaag taattgctgg attagttgca aaaaatttcg
    34501 gaattgctgt agtcccaaat atgaatatgc ttagctttac aaaagtaaaa gtaattcaga
    34561 ttattcaccc aagttgggaa agaaactttt acttagcatt tataaaagat agatatttgc
    34621 ctcctgcaat taaaaacttt aaaaactttg tcattaaaaa cgctcaatta taatttatta
    34681 ataaaggggt tatttttaaa tatcctcttt tattcttttt ataaaataaa aaaatctata
    34741 cttttaaaag tatagattcc taactgacag tcggcatccg agtctcagta attatcgtta
    34801 tacaacagca actggattca gttcctgaat aactaggtta cttacattat atcagatttt
    34861 ttaaaatttg tcaattgtat ctaacgcatt ttttcaagcc atggtccaac aggctctaca
    34921 ataggaactt ctttaaatcc ccaatttctt atatcattca cactcgttgg agtatatatt
    34981 ttgtttctga cagatttgaa tattttgttt ttttctccat attgcataca ctttggatta
    35041 gcttctatta accctcttct tgctctgcta agaggattac ataaaatatc tgctatttct
    35101 aaaccttctc tatagtcagc atcttctttt ttggcaatta taaaaccctt aaccttatct
    35161 cttaattctt catctatatc taagtatatt gttccattat taaatacatc aaaaaacgcc
    35221 ttttgtactt ttaagtttga gacatcatcc cttgactcta taactattcg tgcagattct
    35281 acagtttcat tatttacaaa tgaataaaaa ttctgaagaa catgtataaa agccacaaca
    35341 tacggttcct ttgaaggtgc ataatatttc tttaatctag ctttatctac tgttactgat
    35401 attatagtac actctaatct agatagaaat aaaggcaact catcatagaa taacttaatc
    35461 tgtgaatcat caaacttctc aaatgctctt gattttcttg atatatctgt caaatgtatt
    35521 cctatgttac tggttccaaa acaatactct ttaaatgcat ccatttcttt cctcaaagaa
    35581 catacataat cgccttgact tactgcatat ttatattcaa aaattactcc tgtcaatgta
    35641 aatgggtctt catgatttat atcagctctt ccactttcat caataaacat tatatatttt
    35701 ttctttataa tcttactcac cctcttaaca tatgatgata gcatctatat tcattttata
    35761 tgagttttaa aaatattcca agatttttat ataacttaaa cttaatttta tactaaaaaa
    35821 ttgagatgta aaacaatcaa gcttttattg attgaatttc acatctcaat tataattatt
    35881 tttcaatata tatttttact attttgcaag aatatccatt aatttatcca ttactatata
    35941 agatactccg cctcctattt gataaggagt ttcaactttt ttatttgcaa atactctttg
    36001 ttgctctgat gataatcctg aattatccat taaaactatt ggtgaatgta attttacagc
    36061 taatggtcca gctgataaag catctactaa agcatctgat ttactaacta atacagcctg
    36121 taaatcagta tctccataga atttttctat cactttggca ttagtatcta ctctactatc
    36181 tccatatatt ctatttcctg aaatatcttc agtagttata tcattcattt ttgctattac
    36241 tgaatcgtta attgcacttg gtccacctat aaagtatgca ttttctaatt ttctttctgt
    36301 tagccattta taagattctt ctgtaattcc atctttattg actaatatta taggttgttt
    36361 ttcttcccca gctttagaag ctacagataa agcatctgcc tccccatttc cagaaaccat
    36421 atatgcagtt tttatttctt ctcgatttcc aagttcttca gctattcttg tagcagtttg
    36481 atatctatct tgacctgcta ttctctttgt ttctgtgttg aaagtagttt ttatttcttg
    36541 ctctaattta gaacttattg cattttctcc acctatcaag attactgttt taggtgctaa
    36601 taacttcatt tcttcaacag tttcagttgg taaattagct gtattagtaa gtagtattgt
    36661 tgagtcatag ctacttgcta aaggagttgc tgttatacca tcagctattg cattaccatt
    36721 tactaatatt acagtatctg aactatcagc attccagttt ccaactgaac ttatcttttt
    36781 agctgtatca aatctatttg cacctataat tgtatcccat gtaggattta tagttccatc
    36841 ttcattaaaa gtataatctt tcccatctat tttttgagaa ccagttagca tctttccatc
    36901 tttgtctaaa tagtaagact taccatctat ttgttgccat cctgtctgca ttattcctgt
    36961 tttgtcaaag taatacttat taccatctat ttcttgccat cctgttactg ctaaaccatc
    37021 agatcctaga tagtatttct ttccattctt ttcttgccat cctgtttgca ttactccatc
    37081 tgagttaaag taataagttt ttccgtctat tactttccat ccagatactc ttgctccatc
    37141 agttcctaaa taatattttt tgttattaat tgttttccat cctgtttgca ttactcctga
    37201 agcatcaaag taatacattt ttccatttac ttttagccaa ctattctttt ggtatgttcc
    37261 atcagatttt acataatact tcttaccatt ttctgttttc catcctgttt gatttagatt
    37321 tatcttatat tttgccgcta tctttacata gctgtcgtta ctataatcta taattacatc
    37381 tgaacctaca ggaacttggt caaataacca tctaacatct ttattgtgca ttcttataca
    37441 tccaccagaa atatgctttc ctatagaact ctcattatta tttccatgta ttccatatgt
    37501 atctccataa gttcctttta atgctaatcc catccatcta tctcctaatg gatttcttgg
    37561 acttcctcca ggtatattac ctttataata tggtctattt tttatcttgt taactacttt
    37621 tgttttccct gttggtgttt ctgacccctt tttacctgtt gcaactctaa attcttttac
    37681 aagtttatta tttacaaaat atcctagagt attttttctt gaatttacta taatcacatg
    37741 tttactggct gcgcttgatt ctggtacgcc acatgcaaat actaaaacta aagtcagtgc
    37801 tagtactaaa tactttttta gacttttttt cactataact tccccctctt ttagaaacat
    37861 tactacatgt gtctaattat aacataaaat taccaatacc ttatatttac aaatttgtta
    37921 catttataca tataagtatg tattctactc ttcataccca ttaggattca tactttgcca
    37981 tctccatgaa tcttcacaca tctcttcaag ttcatactta gctttccatc caagctcttt
    38041 ttctgccttt gaagaatctg cataacacat ggctacatct ccagcccttc ttcctacaat
    38101 cttatatggt atttcttttc cacttgcttt agaaaatgct tttactaaat caagaacact
    38161 ataccccttt ccagttccta aattataaac aacaagtcct ggattttctt ctaatttttg
    38221 taatgctttt acatgaccag cagctaaatc taatacatgt atatagtctc taactccagt
    38281 tccatcatgt gttggatagt cattaccata aacactcaat tccttcaatt tacctactgc
    38341 tatttttgtt atataaggca ttagattgct cggaactcca tttggttctt cacctattct
    38401 accactttta tgagcaccga ctggattaaa gtatcttaaa agagctatat ccaatgactt
    38461 atctgctttt gatatatcta ctaacatctg ctctatcata agtttagttc ttccatatgg
    38521 attggttaca gaaagtggaa aatcctctaa tataggacaa gtatgtgggt ctccatatac
    38581 agtagctgaa gaactaaata caaacttttt aacaccatat tctctcatta attcaaataa
    38641 atttaaggta cttattagat tattgctgta atattcaatt ggtttttcta ctgattcacc
    38701 aactgctttt aaagctgcaa agtgtataat tgattcaata ttattttctt taaatacaac
    38761 atgcatttca tctttatttc tgatatcaat attataaaat tttactggtt ttttagataa
    38821 ttccttgatt ctatcaacca ctattgagtt gctattactt aagttatcaa ctataacaac
    38881 ttcataacct gattctaaaa gttctattgc tgtatggctt cctatatatc ctgctcctcc
    38941 agctactaaa actgccattg taattacctc ttttctaata tttatttttc acttactttt
    39001 tttctcatat agtccattaa atcatctttt aaattttctc tctttagagc aaagtctatt
    39061 gttgcctcta aaaaaccaat tttatctccc acatcatatc ttctaccttc aaagttataa
    39121 gcataaatag cctcttgttt tccaagagtt tgaagtgcat ctgtcagttg tatctctcca
    39181 cctttaccag gtgtctgttt ctctaatatg ctaaatattg caggagttat tatatatctt
    39241 ccaagtatag ctatatcaga tggagcttct tcaattgcag gtttttcaac catatcttta
    39301 actttatata ctctatcttc gatatgtttt acatccaata taccatattt attagtatct
    39361 tctttagcta tcttttgaac acctaataca gttgttttat actcattata agtatctatt
    39421 aattgtttta agcacggaac atctgaatct actatatcat cacctaataa tacggcaaaa
    39481 ggttcatcac ctataaaact ttttgcacag taaattgcat gtccaagacc ttttggctct
    39541 ttttgtctta tataatgaat atttaccata tttgatatgt ctcttaccat ttctaacatc
    39601 tctgtcttac ctttttgctc tagttctaac tctaattcaa ctgatttatc aaaatgatct
    39661 tctatagatt ttttatttct acctgttatt ataagaattt cttcaattcc cgattctata
    39721 gcttcttcta ttatatactg taaagttggt ttatctacta taggaagcat ttctttgggc
    39781 tgtgattttg ttgctggtaa aaatctagtt cctagccctg ctgctggtat tattgctttt
    39841 ttaactgtca tctgcatttt ttcacccttc ttcgtaaatt ttctattgta ccaaattaat
    39901 ataccatatt tatacttttt cttcaaactc tatattatcc caatatttaa tgctataaga
    39961 taatataagg tagatgaaat ttcatctacc tttagtttta taagttaata ttgtattgtt
    40021 tatattttat ccaaaactta tacaggtact aaatttcatc taagatgcct tttatatcac
    40081 tatctatatc ttcatctaga taagaatcta aatcttctaa gtcaacttct agttcttgat
    40141 atgtcatatc aacactgaca tcctcatcta tatccatttc tgatattaat tctcctaaaa
    40201 tactatttcc atcagaatct aaaccactat ctatatcttc atctatatag ttttcattta
    40261 aaatttcatc taaatcaatc tcgtaataaa cttcattatt tttttcatcc cctgagtcca
    40321 atcctaagaa ctcatagtta aaagtccaaa cattgtattt acttgacata ctttattcct
    40381 cctgtgaaaa acatattttc atctagttta ttggttccat aatcaacaga gttatatatt
    40441 ttttcaatta tgtcttttct tctttctttt gtactattat ttaatgtcaa ttgtttaaat
    40501 acatatgtat ttgttattct ctcgaataat atttctttta tactatcatc atcaatattt
    40561 ctatagtttt tccacaataa ctcaaataac ttaaacattt ccctactagt ttcatctaca
    40621 taataaggat acatattttc tactaaatgg tttaatcttg atatggcttg ttttaaaaat
    40681 acatcaagac ttgcactttc actttctttt aacattctat aattgtattt cttcttatct
    40741 tctcctgaaa ttacaaagat gatattgtct aaactttttt caacttcatt taaataactg
    40801 cttatattat atgataaatc agacaataga tttttaatct gcttaaacac ttgtacatca
    40861 agtttagtat tatacttttc aaacaaatct atttcttgat tttctaatat tcttggcata
    40921 tatgctgaca ataaatctaa attgtttctt tgttcttgta tttgcttata aagtgaattt
    40981 ataacttcta ttcttatttc atcatttaac tctttttcta aaatcttatc aaattcagat
    41041 ttcatatagt aaatatttcc aaagaaatta aatattatca tatcattcat agctttagac
    41101 caattcttat atatcacttc aatagaattt tctttaagta gaggttgctt tgcatatata
    41161 aatacatctt gcataagttt ttgaaccata cttttactta agtttaaaag tactttttga
    41221 ttattaaatt ttatttccgt ttctacaaaa ttagaatttt cgttttcaag ttctttatta
    41281 attacaatgt cttttatatc actatttttt atagatatga tttctttttg aaaagacttt
    41341 agaatagtca agctatcgaa atcttcttga ataaaaaatg gagcatgttt taatgtatat
    41401 cccactattt cattttctat atcttttagg tcatctattt gcataatttc tctattttta
    41461 tcatttatat gtaggttaaa tacattttta ttatcatata atattatatc ttctcctaaa
    41521 tttaacttag aacaattatc tttcgctgac tttacaatag tcttcttaga tttcttattt
    41581 ataaaaatta attggtcttg atattttact aaaagcatgt ttgtgttttt ataatcaaat
    41641 ccatctatat ttcctgatat cttgcagaat actatttcac aatctttagg aagatttcct
    41701 attttttggt tatctttaac tctctcattt aaatcagatg ggactacact atctatattg
    41761 ttattaaata tagatacaga ccttactata atcccctctc tttccatatg aaagtatccc
    41821 ttcaatgaca ctcttttatc ttctaaaatg tatctttcta tatcatcaaa atttatttca
    41881 aatctatttt tcccactgat aaatataaac ttctcattat ctttattaat tccacccata
    41941 taaaacttat tgtcatctaa acttaatata gtcatattat cctttagata gaatataaat
    42001 tctctttgac ttttgcagat taaatcatat tcatccaaag ttattttcat agtcaaattt
    42061 gctgtaacat ttttacttga attttcactt tttatgtaaa aaggcaagtt atttccatag
    42121 acaattattt gagaatcttc taaaactgcc tctaattttt ctttattgtc tgaaaaacta
    42181 tatatatatt ttacacctgt atcctcatta acttcatctg atttgctgat tattatattc
    42241 cctagatttg ttatatgaag ctttttatat tcttttgagt atctacttat gccactaagc
    42301 tcaaacccat ctgaaagctc atatatgatt ttttctccta atttcaacat accttcacca
    42361 cctaaacaga attataagta ttttataaag gtgaataaaa tgtctcaaaa caaataatat
    42421 tttttttaat actttttatt ctgagacata gtttctcctt ttttataatg ctctaagcac
    42481 cttcaactat ttcttcataa agtttatcta aatgtttaac atattcacga tatccagatt
    42541 tgttctttaa ctcacttctt aaatcttcat atttttgttt aagttcttca gcactcaaag
    42601 aaggagctga ttcttttaat tcttctaact tataatcata gtacttatca tacatagcta
    42661 tatatgtatc aatagacttc ttagctagtt cattacattt ttcttgtgct tctccatatt
    42721 gagaataatc acctattttt attttatagt atccattttc ttgaattatt gttgaagaaa
    42781 tacctttagc ttcatattct tttgctgttt cttttgctgt tttttcaact ttaagtgaac
    42841 ctgcataaac agtgtaatat acacctttac catctttata tgcttccatt tcttttgctt
    42901 tcttttcagc ttgtgctttt tcttgagcct ctttttcagc ttttgccttt tcttctgctt
    42961 cttttttctc tttttcagct tgtgcttttt tctcttcttc agttaattta ttgttagctt
    43021 gttgttgagt tgatgacttt ggaatattct ctttatcatt tttcttattg ttgcctactg
    43081 ttataaaata tcctacacca acaataacca ctataactac tgctataata gtttctttta
    43141 atctactctt cttagaaaca acctcttcat catctaaaga atcttcttta tctgatacat
    43201 aatttttcat ttctttcttg ttttctctat atttgtcctt agaagaattt ttagattttt
    43261 tattactatt ttctttcttt ttaataggta ttactactga tttttcattt tctaattttt
    43321 cttcttttat ttcttttgct tttttatctt ctaagttttt actttctttt tcaagcttcg
    43381 attcattatt tgaagatact ttttcatcta agttattatt tattggtttt tctattttta
    43441 cactacgttc ttcttctata tgttgacttg gttcttcttg ttttatttct ttcaattcat
    43501 tttgctctat ttcttctgat ttcacttgat gattttcaac tggtttatct aaaattatat
    43561 ctggagaaat atcatttaaa ttctcttctt cttgttcagc ttcttcattg tcttttttaa
    43621 taaatccaaa taatttagcc ttctttttac tctttttatt ttctggttca attatatctt
    43681 ctttattgct gtcgtactct ttatctgtag tatctttatc ttctacaacg tcacctatat
    43741 cttgattatt actatctact tcttctttag tcccttcttc agcatcatct tctattgaaa
    43801 tactacttct aaagcaaata tctttatctg cattttttat catgtaaatg tattcttcaa
    43861 tatcgatatc tttatttctt ctagttcttt ttgatgcaat ttcatgattt tctaattcac
    43921 tatagttatc ttttattaga ttctgtgctt tattccatgt atcttcacta atttctgttt
    43981 tatttttaat tacatagtcc acaaattcct taaaattttc aggaccaaat tctccaatta
    44041 tagtcagtct cattgcacct tctataaggt ctctatttct tctctttaaa aattctaata
    44101 caactgttgc acaagcaaaa tctttaataa tttctttgcc aaaaccatat gcttcaacag
    44161 aatgaagttc ttctaatcca cataacttct tatattcatt gtgtattgtt tgagatatac
    44221 tttcattatt taagctattt aacttatcta taaacttcga ttctatatca tttgattttg
    44281 attcatgttt tacttttgaa tttttaattt catttagtag catgtcattt tctgaattat
    44341 ctttacctaa ttgcaaatcc tcaatttcag ttgcttttat ttctactttg ttttgttcgt
    44401 tattctcttc cacattatta ggtaccacat ctttattact agctaatatt ttgtttacac
    44461 agaatataat ttctcttttt aattctcttt tcgcatctgc ttgattttta agaaataaat
    44521 ctccacattc tttcttttct aaacttattt ttctaagaga tatattaaga aggtctttat
    44581 ataggtttaa aaccttataa tccttttcta aacgtcttct tctctctgat agttccattt
    44641 tatcataagc taaaaaacta tttaaatcat tggcttttag agagtctaat ccctctttca
    44701 tagccttatt tacatacttt ctacattttg ctgtagttaa ctctaaatct ttttctaatt
    44761 catctatttc aggtatgtac ttatctacta tccatttgcc aataagtggt tctgtatttc
    44821 ttgctaatgt cttataaaac aatatattaa attttaaaag ctctgcatat tttgcttcat
    44881 taaattctac tttttcaaat ttcttttcca aaacaccatc tagcttttca tttattttag
    44941 actcttgttt taaaaaactt gctgtgacat ttaaaacagt gtttcttatt atattatttt
    45001 cactcaaaac cttcactcct taaatcaatt attttattgt aatatttaca ttgtgcaaag
    45061 ttgctaattt gattatgata tctaaataat tatttactaa atttgctaca tcttatatca
    45121 tatcatatta tttacatcat tttacttttt ctttttatat ctatcttata ttataccatt
    45181 tttaatatct gtactaactt atattacaat attcctcaaa attttaaaag tagattagac
    45241 aaatttacaa ataaaaaaac atcagtttaa actgatgttt ttgactatcg aaataattaa
    45301 gcaagtctat aagcggagtt ctgtattaga taatcatctt tctaggccta ttgtcaccaa
    45361 taggctcaag cgacctacct accggagagt acgagcagca ctctttattc ctatcttggt
    45421 cttgctccag gtggggttta catagccaac tagtcgccta gctgctggtg agctcttacc
    45481 tcgcctttcc atccttacca caatagtggc ggtttatttc tgttgcacta tccttaggat
    45541 cgctcccact aggcgttacc tagcaccctg ctctatggag ctccgacttt cctcatgtaa
    45601 gattacatgc gattatctgg cttacttaat atttatttta cttagttatg ttaacacaaa
    45661 ttcttttaca tgtcaaagta atattatact aaaaatttaa atttattcaa aaatagtgta
    45721 atatagatat ataaactaca tttaactcga ggtgatctat tgaaaaaatt atatagaata
    45781 gtaattaaca ttatactagt attagtaata ctttacagtg gatttaatat atactcaaaa
    45841 cttaccaaat acaatcatga tactaaaata tcctcagaac ttcaaaaaaa agaatataaa
    45901 aaagaggatt tatcaaagat taacagtgat tttaaatttt ggctttctgt tgagaataca
    45961 aatataaatt atccagttgt acaatctaaa gataattctt actatcttga caaagatttt
    46021 tataaaaaag attctatttc tggtacactg tttatggatt atagaaataa atctattgat
    46081 gacaaaaata tcataatata tggacataat atgaaaaata aaactatgtt caacaaccta
    46141 aataagttta aagatgctga cttctttaaa aaaaataata aaataaaaat aaccttgaat
    46201 ggaaaagaat ttttatatga tgttttttct gcttatattg tagaatctga ttatgattat
    46261 ctaaaaacaa attttaacaa tgaatctgat tatcaaaatt acataaatga tattacttct
    46321 aaatcattgt ataaatctcc tattaaggta aatagcaatg ataaaatagt tacactttct
    46381 acatgtacct atgaatttga tgatgccaga atggtgattc atggtagatt gatttaaaac
    46441 tcacagacac agtttaaaac aataatttta aactgtgtca tcttttatac ctataatttg
    46501 taaattagac cactaaaagt atttaataca aaataacaaa tacatcaaac aataaaaaac
    46561 aataaaaaaa gactatgcta aaaacatagt ctttactgga gctggtgata ggaatcgaac
    46621 ctacaacctg ctgattacaa gtcagctgct ctaccgttga gccacaccag cacacctatt
    46681 ttattgtaaa ttagcaaaac taatttttaa aagtta
//
LOCUS       DAMJWC010000025        46192 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMJWC010000025 DAMJWC010000000
VERSION     DAMJWC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.025"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(479..865)
                     /locus_tag="PC503_001626"
     CDS             complement(479..865)
                     /locus_tag="PC503_001626"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527603.1"
                     /translation="MIDEMKPENKRIRELRLNLNLSQEEFANKLNLKRNTISLIENGK
                     RNASERTLNDICKTWSISEEWLKHGVGEMFFIKELDEQFAHLVGELSKMENEVEREII
                     TKMFKLNKKYLTVFDKMIDSLLEIEE"
     gene            1013..1156
                     /locus_tag="PC503_001627"
     CDS             1013..1156
                     /locus_tag="PC503_001627"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527604.1"
                     /translation="MTDINKIREEIYRKLELLGPAKLKLALTKVDILKEIQDIEDENN
                     IQN"
     gene            1134..1385
                     /locus_tag="PC503_001628"
     CDS             1134..1385
                     /locus_tag="PC503_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527605.1"
                     /translation="MKIIYKIKGVKRLKISDFNKNQIGSAVQLQDIRFDTKADCIITK
                     VEKNEILVMYYEKETEEIAYKTLTKEDLILDDYKLKLLS"
     gene            1413..2144
                     /locus_tag="PC503_001629"
     CDS             1413..2144
                     /locus_tag="PC503_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527606.1"
                     /translation="MDLLKDARKKEWFWLENDLIDREDLSIYEKMIYIVLARYSNEES
                     SCFPSYKTISEKAGCSIRQVSNILNELENKELIIRENRNHEGKKEKNSNLYFLISSKA
                     KVQNEVPNVRHEVPNPMAPGALHVRHEVPSKKTYNKKTYIKSNTTTQKESKTDYLDLS
                     FLDLDIEKVKLTKDEYDKLISKFGKKYIHDKIVSLENYIINGKGSRYKSHYRALLTWG
                     NGDASKGIVPEVTKTKNPLSGFKEL"
     gene            2172..2357
                     /locus_tag="PC503_001630"
     CDS             2172..2357
                     /locus_tag="PC503_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527607.1"
                     /translation="MNEKEETVYLNSSNVKLFLGVRDIKEFEELIENVNERICQLQES
                     INKLAQFNIEFDIKSDI"
     gene            2383..2601
                     /locus_tag="PC503_001631"
     CDS             2383..2601
                     /locus_tag="PC503_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527608.1"
                     /translation="MKDEKLELTEKDLHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECKDYFTHIDTFIKLSEMTGVDIFTK"
     gene            complement(2620..2832)
                     /locus_tag="PC503_001632"
     CDS             complement(2620..2832)
                     /locus_tag="PC503_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527609.1"
                     /translation="MNMCKIKTLREKCSLIDDKVEFSGEYKTFPGFTGSKLLECECNK
                     NYICKIQIMTANSNCPLFKKARQLQY"
     gene            2995..3255
                     /locus_tag="PC503_001633"
     CDS             2995..3255
                     /locus_tag="PC503_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527610.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            complement(3248..3436)
                     /locus_tag="PC503_001634"
     CDS             complement(3248..3436)
                     /locus_tag="PC503_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527611.1"
                     /translation="MSQYRVISKECPVINETISLTCEYSAPPGTFGSKLMSTRCDGSH
                     ICDSSSNEECPILKKLLR"
     gene            3574..3891
                     /locus_tag="PC503_001635"
     CDS             3574..3891
                     /locus_tag="PC503_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527612.1"
                     /translation="MERKKHEFTDQDIQRLIEGLRTDPKIREMIFKSKGCETRTSTRS
                     KCEQFVEEKLAYRSYGFETPKYYAKLIADIIDILVYKNVPRDRICGVLYDVERVIPLV
                     VTF"
     gene            3913..5244
                     /locus_tag="PC503_001636"
     CDS             3913..5244
                     /locus_tag="PC503_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2527613.1"
                     /translation="MNYSLEAEQNILGSFLINDSIGYKIRELKENDFYFESHKIILSC
                     MKKIIDSNKPLDLLLLKNELEKIDRLVDIGGVSYITSLTTIVITTSNIDHYIKIIKEK
                     LLKRQISELANELINNSNSDTSIDELIIDINDLKALVTTSSSVNDNYIDASKIKREKG
                     VHKSIDTGFNKLNNMLDGFRYGTLTILTGKPASGKSTIVNQFIAQAITNGEKAFLYSG
                     ELPSFMSMDWFRKTVANDYHIKEYKSVYGGTYTDIPDYAVELISDWIEDKFFLYDEDA
                     ISDEVNLLNTIEHLYLKKGVRFFVLDNLMTIKTGNKADKYERQEQIVSNLKNLAKKYN
                     LVIVLVAHPRKNMGDMKPTMYDVSGASEIVNYADYILSTYRVVDEEEETDDTYLLILK
                     NRITGKQNISFKMNFSERRKRLYTTSEELNRDYKYDVNKQYVQVEIPEDVF"
     gene            5619..6005
                     /locus_tag="PC503_001637"
     CDS             5619..6005
                     /locus_tag="PC503_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527614.1"
                     /translation="MIALEKFAGGVLKEKFNTELQKVLDNIADPNTDFKKTRKISLEI
                     VFKANEDRDLAEVDIKSKATIVEAKATTTKVLIGKDLETGRVEASEFKNQVAGQLVMD
                     IPDSEETNETEENSAGVIDFRNASSK"
     gene            6058..6762
                     /locus_tag="PC503_001638"
     CDS             6058..6762
                     /locus_tag="PC503_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527615.1"
                     /translation="MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEIT
                     TLSGLVDYIKSGIDHKADELLLIQVLTPRKVLLKSPLRKNRDRETYIECVALLPEKRF
                     DRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVAS
                     VSEAIVPNRVKLIPYRTFQEIEQPESEFIFRMSSGPAAGLYEADGGAWKNQAMLNIKA
                     YLQEELKDFKNVNIIA"
     gene            6819..7001
                     /locus_tag="PC503_001639"
     CDS             6819..7001
                     /locus_tag="PC503_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527616.1"
                     /translation="MKMISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVK
                     QMEYRENKYNEGDIAI"
     gene            6998..7375
                     /gene="ssb"
                     /locus_tag="PC503_001640"
     CDS             6998..7375
                     /gene="ssb"
                     /locus_tag="PC503_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2527617.1"
                     /translation="MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYTKKDGTR
                     EVDFIPIEVMGGSAEFCANYLAKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNAL
                     DRKPKDEEKEISFQVLDDEDIPF"
     gene            7356..7940
                     /locus_tag="PC503_001641"
     CDS             7356..7940
                     /locus_tag="PC503_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2527618.1"
                     /translation="MKIFHFKLDGDYVRSLEERNKLVEENINFVWFIIRRYFKVFISK
                     YPYLQDDTFSEGCIGLCKAADYFDSKKGIEFTTFAAVCIKGQIFKFISRYVKKHYRAD
                     IDSFEKCIYKNTHGEEIRIEDRLAGNENVDIENVHVIRSCIKRSKIEDIQKITYLREK
                     GYTQKEIGKILRTNQMTICRKLGKLKSEINILGK"
     gene            7970..8128
                     /locus_tag="PC503_001642"
     CDS             7970..8128
                     /locus_tag="PC503_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527619.1"
                     /translation="MKTKIIGGRENQCPLCNGSVFKIETSIGIVWQCKDCGCMYQDMN
                     CKENKRRH"
     gene            8131..8457
                     /locus_tag="PC503_001643"
     CDS             8131..8457
                     /locus_tag="PC503_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527620.1"
                     /translation="MACVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCDKCYD
                     RLFRSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGGCLEGRKKWL
                     ESEAMK"
     gene            8457..8993
                     /locus_tag="PC503_001644"
     CDS             8457..8993
                     /locus_tag="PC503_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HDF2527621.1"
                     /translation="MKKTLIIVGVVISILIMFACLFLVTKNKAIDLEEQVQSATASVE
                     VQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYP
                     DLKANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIE
                     SKYTEYKAKEDAPQNLFD"
     gene            9005..9811
                     /locus_tag="PC503_001645"
     CDS             9005..9811
                     /locus_tag="PC503_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527622.1"
                     /translation="MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNER
                     YYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTM
                     HTRVVTTKDSKGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLA
                     LKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKV
                     FKGESIQNVLENNNFNTGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK"
     gene            9836..10096
                     /locus_tag="PC503_001646"
     CDS             9836..10096
                     /locus_tag="PC503_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527623.1"
                     /translation="MKCKVYHAIKNIKDANELIDRFETENIFFELNDIDNENVLNGEM
                     NLTDIEDIASLQFILDGDLFIFSSCDEMIFMNKYTQKELGLQ"
     gene            10120..10605
                     /locus_tag="PC503_001647"
     CDS             10120..10605
                     /locus_tag="PC503_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527624.1"
                     /translation="MDLKLISSIPNWKVEDQLAKIDEEVTEFKNAIDTGITKDIIAEG
                     LDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELI
                     NMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNI
                     N"
     gene            10625..10882
                     /locus_tag="PC503_001648"
     CDS             10625..10882
                     /locus_tag="PC503_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527625.1"
                     /translation="MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINM
                     QNGYGSFGAYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE"
     gene            10991..11434
                     /locus_tag="PC503_001649"
     CDS             10991..11434
                     /locus_tag="PC503_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HDF2527626.1"
                     /translation="MQSSKKDNLFSSAEGKLYDYKKIKAEIEKIDIDMQMIKNDYRGC
                     SGVEIKEKTGKTYDIKSVIEIETEEKEKKIALKEKEKRHKELIIEKIDNAMKILSEEE
                     KKIVQYKYFSSSRTSWEYVGRMIGFSASKCKQMRFDIIDKIKGLL"
     gene            11577..12122
                     /locus_tag="PC503_001650"
     CDS             11577..12122
                     /locus_tag="PC503_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527627.1"
                     /translation="MAWNLRSKSFLLSREVLKIKRDITEEISSAAYVPDNLKYYDNVM
                     KETPGMYGRECSLDFIKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILEKSIIDESDH
                     VELVVFKLYLQLENVVKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFTDVVE
                     DLKILVQERQRKNYYGNKECF"
     gene            12126..12770
                     /locus_tag="PC503_001651"
     CDS             12126..12770
                     /locus_tag="PC503_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2527628.1"
                     /translation="MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGL
                     RVGDILALKVADVTDLKLDKKGNKIRVSKDWIRVIEEKRDYNREVFLSDVIKSAIENY
                     TQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAKKVGIKENVATHSLRKTFARHI
                     YDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN"
     gene            12985..13443
                     /locus_tag="PC503_001652"
     CDS             12985..13443
                     /locus_tag="PC503_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527629.1"
                     /translation="MDVNEVEIIDSSYEKGKELTEDQCNMVTLLITGATVTETARIIG
                     VNRKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVM
                     LAANQYLINRIYGTPTSTVIQAEDNSVGMGMDATEIEAAIAKIRIRTSKK"
     gene            13998..15737
                     /locus_tag="PC503_001653"
     CDS             13998..15737
                     /locus_tag="PC503_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527630.1"
                     /translation="MDNLERNIQLIFSYLAKTFIRNGASIKDAEKEANEIIKANSNNL
                     WGVNGLAYQLGKINLEFFCMYFMQDTYLPKEDNAAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGRKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKRFSDDVKYAAQKPVIRNGKTIKRGTTFIALGTLQHKECF
                     YSRLKNLPTWKFKCEKGVLVDNVDELFNSGLWLKFKEILFDFKNTNHLEDAKEFYWEN
                     EKEMKFPILWPSFWDCLDMALSYYENPTSFKQEVQNDVNSIGEKWFKTVRTETREEIE
                     SHTFKKTMLLCDPASAGGSKHDYSAFLVGSESENGLLYGRLAELAKINARTDFDKYID
                     HMIYLLKVYSDITHIYIEKNTFNGADANQLEFKIKNDNVLSYRDIEIINEQQKKNKDD
                     KISTLIPVLSKGQMIFAEEDKEFIQQILDFTGQKYSLHDDAPDISSEFINRINNIKVS
                     ETVNIFDRKLLGF"
     gene            15738..15941
                     /locus_tag="PC503_001654"
     CDS             15738..15941
                     /locus_tag="PC503_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527631.1"
                     /translation="MGGNLLANRSKFEEVQKTLTKKGKKFNVGIGKDEKGYFAYTHRA
                     RSKSYISKQDIPIKVLKFIESTG"
     gene            15954..17231
                     /locus_tag="PC503_001655"
     CDS             15954..17231
                     /locus_tag="PC503_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2527632.1"
                     /translation="MELDLDLIKDIYDDWNSNKSEYDTMYKYYKGETDAISNYKMVTK
                     RSNNKINTNFLKKFINEEVAYSLANKITYTSRSGDEKIINDLEYYTCHWSKKHDSDLL
                     RYALLFGLCYELYYVKDDEIQVKIIKPTDGCHYENENGEIVCFIREFTKGFEDDTYVD
                     VYDKEYIYHFDSNFKEVESPTVNNIFDGNVPISICKRSEELGKNTIFNDIKGLQDAYE
                     TNLSDISNEISDFRNAYLTFSGCNIKEDDLPRMKELGILQVNGDGKIEWLIKDMNDTF
                     VQNTLSSIKENMYEITSHINHNEKMQSNTSSLAVIARLISTEWICSQNNDSIADTLFN
                     RYKLLCIWLNKKYGFDYDYKDIKAKFTPKIPRDDLVVANILSQLGDKLSTETGLSQLS
                     FIDNPHAEIEKAKKEQEIVSEGEILLDESKDYN"
     gene            17209..17970
                     /locus_tag="PC503_001656"
     CDS             17209..17970
                     /locus_tag="PC503_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2527633.1"
                     /translation="MNQKIITKLTEDIYKSAENRTKPFYKYQRENRDKLLLEIAKILL
                     THDIINEYLNINNKDKKNLRSKLNKIINEYSNSYDEEVKDIETILSDSSKNKYSNLII
                     LLGVILKIKDVSNINNKVINKIVNNKVDGKHWSDRLWKNKKGIEESLKKEIKSFLNGK
                     TSVNKIEKAIRDKYSTGAGQTSRLIENEVARCQSEVNEYFFKVQGIIKVMYCADLDSR
                     TCSDCSMHNGVIFYVNEDRPSLPRHCHCRCQYIPV"
     gene            18029..18355
                     /locus_tag="PC503_001657"
     CDS             18029..18355
                     /locus_tag="PC503_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527634.1"
                     /translation="MKVEILGTEYLVIEKLESEDVLLKERAGYCDHSVKEIVIEKINS
                     EEGSLKDLSVYKNEVARHEIIHAFLSESGLKSCSSWATNEEMIDFFAIQFPKIVKVMD
                     KIECLN"
     gene            18381..18983
                     /locus_tag="PC503_001658"
     CDS             18381..18983
                     /locus_tag="PC503_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HDF2527635.1"
                     /translation="MLKKEVLELLKEIEDDAEIDSLLQSTDLFKSASDKKLTIEEFRE
                     LINNDANFKAIIDNEKNKYHSEALENFKKKDMQTLISAEVLKRTGANETEEQKAIREL
                     RESLDKLKKEKQYAEKVSKYKDILVEKKIPTNLIEYLLSDDDDKTNANIEIFENSMKQ
                     YVQSKVDERIKDGSYVPPGKDSAGSLSEIRKQIKQGLNSL"
     gene            19012..19935
                     /locus_tag="PC503_001659"
     CDS             19012..19935
                     /locus_tag="PC503_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527636.1"
                     /translation="MANVLQYVTLFQQELDMQVTVGSTTGWMEKNAGQVIYNGGREVK
                     VPKVTMDGLGDYDRSKGYTQGAVTLEYETMKMEMDRGRTFMLDSMDVNESNFVINASS
                     VMGLFQKQHVIPEIDAYRYSKIFSETAKVDERVKYSYEATVTTILSELKNQLASIQDL
                     SGDIPLIISMSSIIASILEQSSQLDDIEFGDGDIKRIVKSIDNVPIIKVPSKRMKTEY
                     VFRDGKTSGQTEGGFTEGAKALDINWLITPASAPIAVSKTDKPRIFTPDQNQTADAYQ
                     IDYRKYHDLWILDEYLKLCRASVRQAKAAQE"
     gene            19949..20221
                     /locus_tag="PC503_001660"
     CDS             19949..20221
                     /locus_tag="PC503_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527637.1"
                     /translation="MFALIKNNIIKVVEDENSRDKLISKGFKIYSEEVTKENIEKKEE
                     KVKSTSNDLFNLSKPELMEIAKGKNIKGYSTKTKEELIQLLDEYNA"
     gene            20205..20585
                     /locus_tag="PC503_001661"
     CDS             20205..20585
                     /locus_tag="PC503_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDF2527638.1"
                     /translation="MSTMLDNVKLVLGIENDRYDKLIILYINKISEMVLEYCSRQELS
                     TALEGFVEEKVISILSSRFEELKKNSGLDNLEKSLKAITRGDTKIEYNALTLQTAENS
                     ISSSSFLTDTDKKFLSPFCIVSMY"
     gene            20597..20944
                     /locus_tag="PC503_001662"
     CDS             20597..20944
                     /locus_tag="PC503_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527639.1"
                     /translation="MTEADILEMTYLDKMTIIRKLKGWNEETCSNDFSNVVIAENIPC
                     AISRKEEAIVNGDIGSIVVNRKLFCRPEVDIKIGDTINTTYNHGEEAVFKVSKANIYP
                     SHMEIPITELERI"
     gene            20944..21300
                     /locus_tag="PC503_001663"
     CDS             20944..21300
                     /locus_tag="PC503_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2527640.1"
                     /translation="MGIDNLGVFEALALDLGLNASNFNRKIKKFTKETGQELAENIRD
                     ETPVKTEKLKKGWEEKQPEYDTYIVKNEVDYATLVNNGHSTKNGGIVPGSFMVEKGIE
                     RTKENMTSAKANLFDW"
     gene            21309..21758
                     /locus_tag="PC503_001664"
     CDS             21309..21758
                     /locus_tag="PC503_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527641.1"
                     /translation="MLTNRDIIIAVNKRIENEFRYIDIFINEDNIQGFEEACFFVQLL
                     PVSNNIANKVLDTKKIFIDIEYYQKARKNKLNLYDIQSRLEKIFNRNIRVKDRSLIIE
                     NISPSIAKDPVGYKLTFLMTVSYFEEVYFENETFEIMESVDLEIGSD"
     gene            21759..22814
                     /locus_tag="PC503_001665"
     CDS             21759..22814
                     /locus_tag="PC503_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2527642.1"
                     /translation="MGLPEINISFIQAGKTFVKRSGGIVALILKDTKNIGLVEIKEIE
                     DIPENYSAANLDYIKMAMKGNVYPPNKVLVYTLDTDESIDDALDFLETCEFNYLCMPD
                     ETEQDLPKIKTWIKKMREDNKIKVKAITASNSADYEGIINFTATDIEVEGKKYTSNEF
                     LPRIAGFIAGTPSTQSVTYAEIPEVTNIPKLTRAEANTRINNGELILIKESGAIVIAR
                     GVTSFTTITDSKGDIFKKIKLVDTLDQIHNDIKKIIVKNYIGKTQNTYDNKCLLIVAI
                     QLYLQELEKDGLIDEGSTVEINLDAQRAWLKKQNIDISNMEEQQIKEYNTDTLVFLKA
                     RIKLIDAMEDVYLDISM"
     gene            22830..23270
                     /locus_tag="PC503_001666"
     CDS             22830..23270
                     /locus_tag="PC503_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2527643.1"
                     /translation="MKAKIDAKRIISGTFGECWLDNKQLTSTKGMEAKVDIDKEEIKL
                     CGQIMTTYKMIGATGKGSITLYKISTLFGEYVEKMLNEGKEFKVTIISKLQDPDSYGS
                     ERIALYGCMFDDLTLADWEAAKVGEIEVPFTFEGFEYLDKIKEK"
     gene            23285..23701
                     /locus_tag="PC503_001667"
     CDS             23285..23701
                     /locus_tag="PC503_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2527644.1"
                     /translation="MNTVEKLLNMDAGKLKMPSSAFELYCKKLDDTLEIECKAIDPER
                     FDEIRMNSMDVNSGDVENINIYELKVNTILESCSIFSNMELVKKFSAITPKELIKKLL
                     LSGEIDKLYEEVNKVNGIDAEGDKKRQKERAKDIKN"
     gene            23728..23877
                     /locus_tag="PC503_001668"
     CDS             23728..23877
                     /locus_tag="PC503_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527645.1"
                     /translation="MYLLFKYKGIMPSVSYHILRGEKEIVSVFMDQELDERKEEIKSG
                     VGRLF"
     gene            23881..27270
                     /locus_tag="PC503_001669"
     CDS             23881..27270
                     /locus_tag="PC503_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDF2527646.1"
                     /translation="MSSNTKVLQAIIKMRDEASSTLKRVAANTRALHDSSSQASRALN
                     NVQSNLKSVGTSALKAGGLITAGVGGAFAAATKVGTEFESAMSQVKATFGNSLKPGDF
                     EALSKAARDAGKATTKTAADSANALQYMGLAGWDVQKSMHALMPVLNLSEAASMDLGL
                     ASDLVTDSMSSMCLEVDKVSKSGKVLAGAGLSEYLDKVANASTKSNTSIQQLMEAFNV
                     AGGTFSNLKVPLSEATAIMGILANRGVKGTDAGHALNSIMVNLTTGAGQAGKAMKKLG
                     VSAFDNQGKFKGMSNVLKEVANKTKGMTDEQKNYYLSAIGGKTQLKTLQKLLDGVGNE
                     YDSLKKKIDNSKGALKTMSDVMKDNTKGGLATLKSALEETGITIYYQLKPAIASVVDN
                     LTKMTVWFNNLSEPIKRVITNVMLSVGAFGVLLLTIGAVSLIVSKAIGIFGFFVPIIL
                     RAKVAFRAFVIGMKPLSAVFLAVMGPVGWTITAVIALSVAFTIAYAKSEVFRNKVNSL
                     VKSFTEFAKPIVNFCMPALKQLGEKFKELLSAFGPLFASILNLGSVIMKVLGPVLIGV
                     IGFHIAKLVLILSTLATAFKAVVDTITNVLNGLASILNGVFDLIIGIVTGDSKKMMDG
                     VKQIFDGGTKIIKSIWKGFIDFVTAPIQAIADIADSLFKDKAKWLTDKWRDLRTFLEN
                     PIEATAKISTKTNVNIPGSKAADAAGKSTPNTGGLKQTVANLKGSFSDFKTFIKPMTD
                     SISQGVESGKTKFTELQNKILNDVKPALKVLEDSGVNFKDKFKESITSIKDKFNELKN
                     ILAGNIKTNIDNLVKAFEPLKPHLDNLKDCFDKVKKAITDFFTPAKQVGDTVNKVSQP
                     MDSVKKSTDGIKLSFQSLTQALAPVKAWFQGFMPFLSQIGQQLLPSIGIAIAGVVGGI
                     ILAFTWVLNTLTAIITTVSGIINGIMSFISGIINVIMGLITGNADQTMDGLKQIFDSG
                     VGVIKSIWNGLVDLVSGVLEPVIDLADSLFKDKVKGVKEAWNKLKDFFKHPIKGTIEI
                     FKKGPSLQIGKGADAAGKSPRKAFGINRVPRNDYLIRAHEGEKLLTKQEANQYKRNSS
                     NGSLFLDKLADTIIVREEADIDKIVRKINKKISLAKIGGVL"
     gene            27317..27793
                     /locus_tag="PC503_001670"
     CDS             27317..27793
                     /locus_tag="PC503_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDF2527647.1"
                     /translation="MNKKILVLTISIILSLSLVGCSTNNSKNRDSKSKQNTEEVKNHK
                     IGEVVDLDGAKVSVKNIRKLETNSNDYAVEIEITNTGDNDLQSDYLENYILKSSDNTT
                     GEAINNQELNGELMFDTIRPGDTLKGEIAFELTKDATPKTLEIAYENVGKYTVFDL"
     gene            27851..28486
                     /locus_tag="PC503_001671"
     CDS             27851..28486
                     /locus_tag="PC503_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2527648.1"
                     /translation="MEIWLRQANNTFRFPVIPPSFEINGSATINTSNILSVGDIAVFG
                     GLGLKTIELSSFFPNQEYSFCNYNGFPKPYDCVNLIESWMKEGYILRFIITETNINFE
                     CIIADFNYREQDYSRDIYFTLSLKEYRRIQISKVNINNDEKLSSEKNVPLTKGFDTKQ
                     KTHKVVEGDTLFKIAKKYYSNGDLWEKIYKANEDEIKDPSVIKNGWVLIIP"
     gene            28727..30244
                     /locus_tag="PC503_001672"
     CDS             28727..30244
                     /locus_tag="PC503_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2527649.1"
                     /translation="MIIDRSKDSSNNNIDFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFVDNKFPLGNLPKTNVKYTKMFIGVTGYDTIMSVYTEASKTTKKKYMIESNLDKFN
                     VIEKGVVTLNITFEEGFNLINTNFSESIENVKNKVLVVDQYGNKISEKINDSIFKDVG
                     VIMQKVIQQQENSTIDIDGEFKGIEKTCSLKGYGDITCVTGRGVKVKDSYTKLIGLFY
                     IDTDKHTWQNGDYQIELELNFENIMDEKSAGQDEQKEDGSEYTGGTEYPAEFTAYCPR
                     KEEGGNTDCRGKKLDPSKKTCAAPMVGAYEKSYYTKDFLNKHPLMRYGDEIQLVTGVS
                     SRDGTYKVNDNGPAIIIEKDGTYHIDILFGNVEEANNFGRRKGKIIIGGYSGNMTEKA
                     KTVISEARKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVNLPRTSSQQSKVGKKVEK
                     NNLQAGDLVFFHNPVSHVGLYVGNGEFLHAPQTGDVVKISKLSNRKDFNTARRVL"
     gene            30258..30590
                     /locus_tag="PC503_001673"
     CDS             30258..30590
                     /locus_tag="PC503_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2527650.1"
                     /translation="MADPINEFIGIIRQEGKFHNEPSFFIGKIKSKLPDLKIEINNII
                     LEKEDILIDSWMLDRQIELFDTETSQEHKHEIKNPFIDTFESGNTVIMFKIGEKFAVV
                     SKLVSLDE"
     gene            30583..31017
                     /locus_tag="PC503_001674"
     CDS             30583..31017
                     /locus_tag="PC503_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2527651.1"
                     /translation="MNNTIFPFMGVPEDYISPDNEELPIFKEFAWDFNKDEKIIENGD
                     FKIVERNEAIKVWIYKTIKTDKYVHLIYDWSYGTDIKNLIGQKYTKGLTESEAKRYIQ
                     EALLTNPYILEVNITNAEFEDDNLSISLNVKTIYGEEEITFV"
     gene            31010..32062
                     /locus_tag="PC503_001675"
     CDS             31010..32062
                     /locus_tag="PC503_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2527652.1"
                     /translation="MYNGQSFSTLNNRTLNNINLPLYKGQGSSLYNIVSPINSELAQL
                     YIELSYIHKRVFIQDNFDDFLDRRVNEFGVYRKLGTEAIGEVTFEGKIGTQIPNGTII
                     SHSDLLFVIIKDITIDENSKLNVSPIQALEIGIKYNLSANTEFKLIEEITGVTKIYNE
                     LDLKGGTEIETDEELKERFYKIQKNQATSGNKAHYQSWALEVEGVYNAKVIPRWDGPG
                     TIKILIYGQNNQSVDNEVLQRCTEHIEEEKPIGPTVTIVTPSTFDINISATLTLENGY
                     DIESIKVVFLDIINSYLIENSREIVYIKVMSLLASIEGIHDIKNLLVNGDVKNIIVDE
                     EKVPAVSSAIFDIEVS"
     gene            32064..32672
                     /locus_tag="PC503_001676"
     CDS             32064..32672
                     /locus_tag="PC503_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2527653.1"
                     /translation="MKLIDYLPSFANNEIDIQIQEALENELLTLIDEKDDLLEQFFID
                     TATWGLDDWENLLSIKVNYKLDFDTRRSNIKAKMRGKGTTTIEVIKAISEAYTKTNVD
                     VEVFSNLFSFTLSFITNNCSYNTILELDKKIEEIKPAHLEHKFERILFNKNELYTGAA
                     ISTGETVTIYPYVPRNLESFGEIAICSGNDRALEKVTLYPKK"
     gene            32689..33471
                     /locus_tag="PC503_001677"
     CDS             32689..33471
                     /locus_tag="PC503_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2527654.1"
                     /translation="MTEQQYFTLVTDIGKAAIANASITGEKVDFAKIKVGDGGGSSYT
                     PNESQTALKNVVWESTLEHAQGDKDNPNWVVIQKFIPGDVGGFEIREVGLFDSKDQLL
                     AISSYPTTYKPTADSGTVKELLIKVILVVSNVANINLKVDPTVILATLKDIQELDTKI
                     DTTKTELTSNIETAKTELNTKIGDTTQLTTTDKTNIVSALNEVKTSVDSIETTADKTS
                     IKDTDNLFESDNVEGALKEVMQEVKGNRSSIISTINSNLIPM"
     gene            34067..34555
                     /locus_tag="PC503_001678"
                     /pseudo
     CDS             34067..34555
                     /locus_tag="PC503_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893144.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34957..35304
                     /locus_tag="PC503_001679"
     CDS             34957..35304
                     /locus_tag="PC503_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527655.1"
                     /translation="MNRNNRIIYDQTGKIWLQTGEAIGDIQELSEITELNFIDVEFGS
                     IDYSKQYIESINPVTKELNIKNIEVVLTDEQKRLEVLEKELNMLKEENKNRDSEIVNT
                     AFEVGNIKLNNNL"
     gene            35316..35486
                     /locus_tag="PC503_001680"
     CDS             35316..35486
                     /locus_tag="PC503_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527656.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTGL
                     LNKEETPVEPTI"
     gene            35516..35797
                     /locus_tag="PC503_001681"
                     /pseudo
     CDS             35516..35797
                     /locus_tag="PC503_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36105..36572
                     /locus_tag="PC503_001682"
     CDS             36105..36572
                     /locus_tag="PC503_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2527657.1"
                     /translation="MSKSYFNTKLGGSMNVTIVFLATNIFIKLVILAIAFDTLLGCLR
                     AIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLG
                     ISEFFSILFILYESVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGK"
     gene            36576..37406
                     /locus_tag="PC503_001683"
     CDS             36576..37406
                     /locus_tag="PC503_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2527658.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADIFRKE
                     GHKVDVIICPEKQFKTKSEEKSYKIPRVNAGGYDLLIELHLNASDRQGKGSEVLYYSN
                     KGLEYATRICKKLGTVFKNRGAKLDKSLYILNSSKPTAILIESFFCDNKEDYEKAKKL
                     GYEGMAKLIVEGVLNKSIESNEVKQMYKHTIVYSGDDRVSADILGLYYKRAKESYLVI
                     DIKDYKPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTMDKVIEFVKEKL
                     "
     gene            37478..38584
                     /locus_tag="PC503_001684"
     CDS             37478..38584
                     /locus_tag="PC503_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDF2527659.1"
                     /translation="MLTFLDLFAGIGGFRLAMERAGHKCVGHCEYDKFANLSYKAMHN
                     PKEDEWFEKDIREIRAENIPKADVWCFGFPCQDISIAGNKLGFKGNRSSLFFSVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNRGFDFAKLLIELDEIGYNAEWQNLNSKNFRVPQN
                     RDRIYIVGHLRRRSTREVFPITGTSRKTTLEQLNNPNHSSNRIYNSNGLSKCLLSKGG
                     NNTGLYRVGNINPSGNGAGGQVYSSEGFSPTLTTGKGESPKILIKENTKKGYIKASIG
                     DGIRLDHIEGKTGRGRVQHKKSCTLTTASNAGVIGKKFRVRRLTPKECFRLQGFPDDY
                     YDRAASVCSETQLYKQAGNSVTVDVVEEIAKKLK"
     gene            38722..39057
                     /locus_tag="PC503_001685"
                     /pseudo
     CDS             38722..39057
                     /locus_tag="PC503_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894425.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(39068..39583)
                     /locus_tag="PC503_001686"
     CDS             complement(39068..39583)
                     /locus_tag="PC503_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527660.1"
                     /translation="MTWSDLKEKNINEVVDCINNKLSEFESLKKVGDELGANESTIRK
                     WLNKKGYKRTGNKFVEDNKSYDDKYHIDSISSKIDDDIKYLSSEIDNIKNVLEWFKTK
                     DDSYHICVIKENDISIDLPDQSIKRTTVRINNTVWEMFNKFADENKHYDKHDLLSQLL
                     LESLLKYVKSR"
     gene            complement(39666..40571)
                     /locus_tag="PC503_001687"
     CDS             complement(39666..40571)
                     /locus_tag="PC503_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HDF2527661.1"
                     /translation="MSKLGIDIGNYAVKTSTDDIFESKVTEVKNFGSDSDSIKIGNKT
                     YYLGEGDEEINIVKYEKENFLPLLLGAICRNTDDEIVDLGLGLPVKQFAGLRKNLIEK
                     LQGKEYHVEFTRGNETTKRDITIRSIQTFPEGVTGYLYYAKDIVDQIAGRDVVLVDIG
                     GKTTDIALVQGNKATDPYSINVGTINIYDAIKKSLEMDERFLGKVEIKREKIQDYINK
                     GFYLNGEKQDIKKNIDASISLFKEIYNELKLNYPVSTAAVVVMGGGAKLLGEAFKKNI
                     PGIIVMSDVDKHVFANAKGYKKMMK"
     gene            complement(40591..40794)
                     /locus_tag="PC503_001688"
     CDS             complement(40591..40794)
                     /locus_tag="PC503_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527662.1"
                     /translation="MSRIVLTFKNNDKEKAIEKFLDEKLSATAYLKELVWEKMQEKKD
                     NAVVEQKKEIEDPANNFDFGSLE"
     gene            complement(41043..41501)
                     /locus_tag="PC503_001689"
     CDS             complement(41043..41501)
                     /locus_tag="PC503_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527663.1"
                     /translation="MKKTIALLLTLCAVMIPFTAFADGNDYEGTGNSQTVELIGQPNS
                     DSPSTKSVVVPGGTANLTAMSGGQLSWRVTSTLGNILGFEGNIDVYKAGKIVSSQYVG
                     FRLAGTTKTGVVTFKGLKKGSYIAKFKGKGVCTGGIILFSSPAEASFTIR"
     gene            complement(41536..41838)
                     /locus_tag="PC503_001690"
     CDS             complement(41536..41838)
                     /locus_tag="PC503_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527664.1"
                     /translation="MEVNLHTGKDEFFKSHEVAKNYIGGLYKLIDVYKFSMESVSVLT
                     RIDLDKLNNFYAGEASLNYDELCLIESVIITPLVGAFETAEHNYNMIIKARKERKL"
     gene            complement(42226..42378)
                     /locus_tag="PC503_001691"
     CDS             complement(42226..42378)
                     /locus_tag="PC503_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527665.1"
                     /translation="MDNFLFNVLASLTASVVVYLISELFKKAKSHSRAKSDLQVEFKF
                     IFKFKK"
     gene            complement(42498..43232)
                     /locus_tag="PC503_001692"
     CDS             complement(42498..43232)
                     /locus_tag="PC503_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2527666.1"
                     /translation="MYYVYKYINLDTEECLYVGKTENICDRHASHLSNKKENWCNKNL
                     RFEYIELDNKYTMDFYEIYLINKLEPKFNITGKGEMDIAKTSFSYNGQWVIYSERDLM
                     SSLASKRCGINYEVNAKMLGIMRKLKKISSNEEIFIGNENIRIKYYFETVLEGINLEP
                     CILSVAYKTLKESTVGTVISVKREYLSENVCLIIDSIFLNEIMKDPLMSKSDIKDLNS
                     QVNDILKIIGVDCEWNKLSDYCSANS"
     gene            complement(43252..44439)
                     /locus_tag="PC503_001693"
     CDS             complement(43252..44439)
                     /locus_tag="PC503_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDF2527667.1"
                     /translation="MEKKEILMQPNNLIKSKYDFTNVENKLFYKILFNAQKQQNSSYV
                     TTISKEELKVFMKNNNDYEHKNIKEILNMFQQSVLEFDYIEETTGKLKTFGSGLINTY
                     ELDHTDQIYTIMMHEVLYNHITDFVKMQKKKNGYTAINLSVLFNFRGAYTQRLYTLFR
                     LWSRENKEVEIKYKLDELRFYLKLKDNVYPEYKYFKQNVLKRAMNEINKKGNMVVSIK
                     EEKRKNRKIDEIIFSVIDYEPRKYFDKDILVEDYIPKKKQDNEVSFSFYIPNENIFTT
                     GTIKLFKEDFKEFDFKKDVYLNAFNKSIAIAFERDNTDIINTKNYDFFKSTLSNKISE
                     VIIHQKDDLKFKEELDKYWDDEDVKKEEREVDYSKDPVRLETVRRNLFDQGLVNEEGY
                     YYK"
     gene            44859..45548
                     /locus_tag="PC503_001694"
     CDS             44859..45548
                     /locus_tag="PC503_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDF2527668.1"
                     /translation="MLENRKQIQKEIYLPIATYCLKDKQYYIKEYGALLIKSAENSDI
                     FNTHKNRILYKNKLDIQEIANELNVNKATIQRNIKKLEKLDFKILKIENTLNGIVYCL
                     PSENNIDLNKFALINYEMLKKMVNKFKSNTIKVYFLLKTITTETNFKPATNSFIAENI
                     GLSSKSKNNLDIITSSVKTLEENKYIETKKVNVYEYDKEKLREVPKIRKVYRICNFDE
                     WKKEIDKNKVY"
     gene            complement(45697..46080)
                     /locus_tag="PC503_001695"
     CDS             complement(45697..46080)
                     /locus_tag="PC503_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2527669.1"
                     /translation="MKIKKIPESELLVMMFIWDSEDKEVASTEILKTLGEKYEWKKST
                     MLTFLRRLVGRGFLEVVKKDRFTYYKALIEKEEYLKVETKSFFSFFHKNSFESFISAL
                     HDDEEVSENKLKSLEKFIEDWEEDK"
BASE COUNT        18543 a         5381 c         7705 g        14563 t
ORIGIN      
        1 aaaaaaaaat taagcaggag taaaaaaaat aaaatattat caaaatttat caatataaaa
       61 agaaatataa gtataaattt ttctctttgt atattgattg tatacaattc tatttttgta
      121 aaattaaatt ttaaaaaata atcaaaaatc ttaattttca atattgaata caattaaatt
      181 ttcaaactca tctagggcat gacatacaaa agcaaaaaac attaatttag tatctgataa
      241 aaatttaaaa attgtaaaag ggggaagtct gttatttttc agaagcaatg taattgtaaa
      301 aatataaatc agaatatttt gaaaatatgg gggataaact tatgatggat ttagaaaagg
      361 aaaaacatga aataattgaa attataaaaa aattaaatat tgataaagat aaaaggaatt
      421 tattgatgat aaaaaattat atccttggac ttttaaaaaa atagaagaat agcaattgct
      481 attcttctat ttctagtaag gaatctatca ttttatcaaa tacagtcaga tattttttat
      541 tcaatttgaa cattttagtt ataatttctc tttctacttc attttccatt ttacttagtt
      601 caccaacaag atgggcaaat tgctcatcta attctttgat aaaaaacatc tctccaactc
      661 catgcttaag ccattcttca gatatgctcc aagtcttgca aatgtcgttc aaagttcttt
      721 cgcttgcatt tcttttacca ttttcaatta aagatattgt gtttcttttt aaatttagtt
      781 tattagcaaa ctcttcttgg cttaaattga gatttaatct tagttctctt attcttttgt
      841 tttctggttt catttcatct atcattatta tccctccata tgaaatatta tattttaaaa
      901 gtgcttacaa gtcaacaaaa ataaaagaaa aaggtattac aaaatagttg acttgtaagc
      961 agacatgtaa tataattgta ttacacaatc aacaaaagcg aggtgattga aaatgactga
     1021 tataaataaa attagagaag aaatatatag aaaattggag ttacttggcc ctgcaaaact
     1081 aaaattagca ttgactaaag tagatatatt aaaagaaata caagacattg aagatgaaaa
     1141 taatatacaa aattaaaggg gtgaaaagat tgaaaatctc agattttaat aaaaatcaaa
     1201 taggatcagc agttcaatta caagatataa ggtttgatac aaaagctgat tgcatcatta
     1261 cgaaagtaga aaagaatgaa atactagtca tgtattatga aaaagaaaca gaggaaatag
     1321 catataaaac tttgactaaa gaagatctaa tacttgatga ctataaactt aagttattat
     1381 cttaaagtaa tttcagaagg gaggtgataa ctttggatct tttgaaggat gcaagaaaaa
     1441 aagagtggtt ttggctggaa aatgatttga ttgatagaga agatttgagc atctatgaaa
     1501 aaatgattta cattgtctta gctagatata gtaacgaaga aagttcttgt ttcccaagtt
     1561 ataaaacaat atcagaaaaa gcaggttgca gtataaggca agtatctaat attttgaatg
     1621 aattagagaa taaggaacta ataataagag aaaatcgtaa ccacgaaggc aaaaaagaga
     1681 aaaacagtaa cttatatttc ttaatatctt caaaagcaaa ggtacagaat gaagtgccta
     1741 acgttaggca tgaggtgcct aaccctatgg caccaggtgc cttacatgtt aggcatgagg
     1801 tgcctagtaa aaagacttat aataaaaaga cttatataaa aagtaatacc actacacaaa
     1861 aagaatctaa aactgattat ttagacctat cattcttgga cttagatata gaaaaagtaa
     1921 aactaactaa agatgaatat gacaaactta taagcaagtt tgggaagaaa tacatacacg
     1981 ataaaattgt tagtttagaa aactatatca taaatggtaa agggagtagg tataagagcc
     2041 actatagggc tttgctgact tgggggaatg gagatgctag taaaggtata gtaccagaag
     2101 ttacaaagac taagaatcct cttagtggat ttaaagaact ttaaaaacta aatagtaagg
     2161 aggtagatag gatgaatgaa aaagaagaga ctgtttattt gaatagttct aatgtgaagt
     2221 tattcttagg cgttagggat attaaggaat ttgaggaatt gatagaaaat gtcaatgagc
     2281 gaatttgtca actccaagaa tcgattaata aacttgccca atttaatatt gagttcgata
     2341 ttaagtcaga tatttagtta agtataaatt aggaggttgc ctatgaaaga tgaaaagtta
     2401 gaacttactg aaaaagattt acactgtatt gcaagacatt tacaaaatga agttatggag
     2461 atggtgttta gagggaatat agaagcccct acatcatgcg aagtttgcga ttacttgcaa
     2521 gaatgcaagg actatttcac ccatatagac acttttataa aattaagtga aatgacaggt
     2581 gtagatattt ttactaaata aatttagtaa attaaaattt tagtattgta attgacgtgc
     2641 ttttttaaaa agaggacagt tgctattagc agtcattatt tgaattttgc aaatgtaatt
     2701 tttattacat tcgcattcta aaagttttga tccagtgaat ccaggaaaag ttttatattc
     2761 accagaaaat tcaactttat cgtcaataag agagcatttt tctcttaagg ttttaatttt
     2821 gcacatattc atcaccaccc tataattaat ttgaacatac tgtcaatatg ctccgattaa
     2881 ttataacatg caaattatca tgatgtagaa ttaaagcata ggtcaattaa atttagttat
     2941 aaaatcaatg aaacagataa ataattaaat gttaaataaa ttagggggtt gttcatgaaa
     3001 gaggaaaagt tagaacttac tgaaaaagaa ttgcattgta ttgcaagaca tttgcaaaat
     3061 gaagttatgg agatggtgtt tagagggaat atagaagccc ccacatcatg tgaagtttgc
     3121 gattacctgc aagaatgtga gggagatttt acctgtatgt atcattcttt tactaaatta
     3181 agcaaaataa caggtgtaaa agtgactgca tttaagtatt gttttccaga tgaaaatccc
     3241 aaagctacta tctaagaagt ttttttagaa taggacattc ttcattagaa gaagagtcgc
     3301 aaatatgact tccatcacat ctagttgaca ttaacttaga tccaaaagta cctggaggag
     3361 ctgaatattc gcaagtaaga gaaatggttt cgtttattac aggacattct ttgcttataa
     3421 ctcgatattg gctcatactc tcaccacctt tctaattaat ttaaacatat tggaagtatg
     3481 tttaaattaa ttatagcatg taaattatca tggtgtagaa tagtttcaaa tcaaaagaag
     3541 caactaaata gttaaagaca ggaggtatgc taagtggaaa gaaaaaaaca tgaatttaca
     3601 gatcaagata tacaaagact tattgaagga ttaagaactg atccaaaaat aagagaaatg
     3661 atatttaaaa gtaaaggttg tgaaactaga acaagtacaa gaagtaaatg cgaacaattt
     3721 gttgaagaaa aacttgctta tagaagttat ggatttgaaa ctccaaaata ctatgcaaaa
     3781 cttattgccg acataattga tattttagtt tacaaaaatg ttccaagaga tcgtatttgt
     3841 ggggtattgt atgacgtcga aagggtgatt cctttagttg tgacatttta ataataagct
     3901 gggggtgatt aaatgaatta ctctttagaa gcagagcaaa acattctagg aagttttctt
     3961 ataaatgact ctataggtta caaaataagg gaattaaaag aaaatgattt ctactttgag
     4021 tcacataaaa ttattttatc ttgcatgaag aaaataattg actcaaataa accactagat
     4081 cttttgcttt taaaaaatga attagaaaaa atagatagat tagtagatat tggaggcgtt
     4141 agttacatta ccagtttaac aactatagtt ataactactt caaacataga tcactatata
     4201 aaaatcataa aagagaagtt acttaaaaga caaatttcag agttagcaaa tgaattaatt
     4261 aataattcaa attcagatac aagtatagat gaattgatta tagatataaa cgatttaaaa
     4321 gcacttgtga cgacgagcag tagtgtaaat gataattaca ttgacgcatc aaaaataaaa
     4381 cgtgaaaaag gcgtacacaa gtccatagac acgggtttta ataaactaaa caatatgcta
     4441 gatggattta gatatggaac tcttacaatt ttaactggta aacctgcatc tggtaaatca
     4501 actatagtta accagtttat agcacaagca attacgaatg gagagaaagc atttttgtat
     4561 tctggagaat taccctcttt catgtctatg gattggttta gaaaaactgt agctaatgat
     4621 tatcacataa aagaatataa aagtgtctat ggaggaacat acacagatat tccagattac
     4681 gccgttgagc ttatatcaga ctggatagaa gataaatttt ttctctatga tgaagatgca
     4741 ataagtgatg aagtaaatct actaaatacc atagagcatt tatatttaaa aaaaggggtt
     4801 aggttctttg ttcttgacaa tctaatgaca ataaaaactg gcaataaggc agataaatat
     4861 gagagacaag agcagatagt aagcaactta aaaaatctcg ctaaaaaata taacttagta
     4921 atagttttag ttgcacatcc tcgtaaaaat atgggtgaca tgaagccaac tatgtatgat
     4981 gtgtctggag caagtgagat tgttaattat gcagattata ttttatcaac ttacagagtt
     5041 gttgatgaag aagaagagac agacgacact tatttattaa ttttaaaaaa tagaataaca
     5101 ggaaaacaga atataagttt taaaatgaat ttttcagaaa gaagaaaaag actttacacg
     5161 actagtgagg agttaaacag agattacaaa tatgatgtaa ataaacaata tgttcaagta
     5221 gaaattccag aagatgtatt ttaaaaaaag tataaaaaat aggaaatttt attaagtaat
     5281 gattttataa gaaaaaccaa tattgaataa tttaaaaatt caatattgaa aaaaatcatt
     5341 tttcaatatt gaaaaacgga ttttgaaaaa gtattgaatt tcaatactaa aaaaagtttg
     5401 aaaatatagc atttacaagg tttatataaa ttaatttcct gacaatgtac acacaggttt
     5461 agatatgcta gcaaaaaaac ttaaaagtag tgtaaggata aaaaggctat ataaatttat
     5521 aaaaagattt aaaagtgtta ttaaattaga gctaaagttt attaattaat ttcctcgtag
     5581 aaaaatatta ttttaaataa ataaaggagt gattttacat gatagcatta gaaaaatttg
     5641 caggtggagt tctaaaagaa aagtttaata cagagttaca aaaagtttta gataacattg
     5701 cagatccaaa tacagatttt aaaaaaacaa gaaaaattag tttagagata gtgtttaaag
     5761 caaatgaaga tagagatctt gctgaagtag atataaaatc caaagcaact atagtagaag
     5821 caaaggctac aacaactaaa gttctgatag gaaaagattt agagacagga agagttgaag
     5881 cgtctgaatt taaaaatcaa gtagcagggc agttggtcat ggatattcca gatagtgaag
     5941 aaactaatga aacagaagaa aatagtgctg gtgtaattga tttcagaaat gcaagttcaa
     6001 agtagtttaa gaaagtaagt aaaatataaa tttaaataaa aaaggagaat aaaaaaaatg
     6061 ataagaaatg caatggaata tttagttaag ttaggaaaaa gagaaacagt atgtgtagat
     6121 gggtttaagt acacaacaga tgcattagaa ataataaaag aaccaaaagc taatgaatta
     6181 gaaataacta cattgagtgg tttagtagat tatataaaaa gtggcataga tcataaggca
     6241 gatgagttgt tattaataca agttctaact ccaagaaaag tgcttttaaa atctcctttg
     6301 agaaaaaata gagatagaga gacatatatt gaatgtgttg cactactacc agagaaaaga
     6361 tttgacagac ctttagactt agatagtttt aacataatgc tacaatcagc atttataaag
     6421 aataatgata gagatacact tttaaaaatt gcaggaaata tccaagaatc tacagtaaaa
     6481 aatgtgggag atgatggagt ttctcagtct gtaacaataa aaacaggcgt agctagtgta
     6541 tcagaagcaa tagtcccaaa cagagtaaag ttaattcctt atcgcacttt ccaagagata
     6601 gagcaaccag aaagtgagtt tattttcaga atgagttctg gaccagcagc aggattatat
     6661 gaagcagatg gtggagcatg gaaaaatcaa gcaatgttaa acattaaagc gtacttgcaa
     6721 gaagaattaa aagattttaa aaatgtaaat ataattgctt aattgaaaat ctaagagggc
     6781 ttacaataag tcctcttagt aaaaaaggag gggattagat gaaaatgatt tctcatatga
     6841 acattttaga aagagcagaa tttacagata aaatagctaa tgcaatcatg tctgcaaata
     6901 aagaaattga aagaggctgt gcctttaatg aagcagttga gattgtaaaa caaatggaat
     6961 atagagaaaa taaatacaat gaaggagata ttgcaatatg aataatgtag ttttagttgg
     7021 aagattagca agagatccag aattaagata tataccagag tatggtactc cagttgctac
     7081 ttttgcattg gcagttgata ggggttatac aaaaaaggat ggaactagag aagtcgattt
     7141 tataccaatt gaagttatgg gaggatccgc agaattttgt gctaattatc tcgcaaaagg
     7201 aagaatggtt tcaattcaag gccaaataag gatagaaaaa tatgaaaaag atggagagaa
     7261 aaaaactttc acaaaagtaa gaacaaaaat tgttaatgcg cttgatcgca agccaaagga
     7321 tgaagaaaaa gaaattagtt ttcaagtttt agatgatgaa gatattccat tttaaattgg
     7381 atggtgatta tgtgagaagt ttagaggaga gaaataaatt agttgaagaa aatataaatt
     7441 ttgtatggtt tattataaga agatatttca aagtatttat ttcaaaatat ccatatcttc
     7501 aagatgatac attttcagaa ggatgtattg gattatgtaa agcagcagat tattttgata
     7561 gtaaaaaagg tattgaattt accacttttg cagctgtgtg tataaaaggt caaatattta
     7621 aatttataag taggtatgtt aaaaaacatt acagagcaga tatagatagt tttgaaaaat
     7681 gcatctataa aaatactcat ggtgaagaaa taagaataga agatagattg gctggtaatg
     7741 aaaatgtaga tatagaaaat gttcatgtta ttagatcttg tataaaaaga agtaaaatag
     7801 aagatataca gaaaataaca tacttaaggg aaaaaggata cactcaaaaa gaaataggca
     7861 aaatacttag gactaaccaa atgacaatat gcaggaagct tggaaaatta aaatctgaaa
     7921 ttaatatact aggaaaataa tataataatt taagttcatt ggaggcaaaa tgaagactaa
     7981 aataattggt ggtagggaaa atcagtgccc actttgtaat ggtagtgtat ttaagattga
     8041 aacatcaatt ggaatagtat ggcaatgtaa ggattgtgga tgtatgtatc aagatatgaa
     8101 ttgtaaagaa aacaaaagga ggcattaagt atggcttgtg ttataaagtg tgatttttgt
     8161 ggtgaaacaa tagcagaaat tctaaacata aaggtattca gaattgatga tgaaggtaat
     8221 ataatgagta tcggaaaaga tgtatgtgac aaatgttatg acagattatt tagaagtaac
     8281 ttgaataaga agatgactaa ttatgaaaag ataaaaaata tgagcaaaat agaaatggct
     8341 gaatttcttg caaatggcgg aagtggatgt actagttgtg cttatgattt tcaagaatgc
     8401 ttaggcggat gtttagaagg tagaaaaaaa tggcttgaaa gtgaggcgat gaaataatga
     8461 aaaagacgtt aataatcgta ggagtagtta tttcaatatt aattatgttt gcttgcttgt
     8521 tcttagtaac taaaaataaa gcaattgatt tagaagagca ggttcaatca gcaactgcat
     8581 ctgtagaggt gcaagaaaaa aggagaattg atttaattaa gaacatagta gactgtgtaa
     8641 aagactatgc taaatatgaa aatagaacat taaaagaagt aactgacatg agagtaagtg
     8701 caaatgatga atctatcaag gaagcaaaat taaatataca agcagtagca gagaagtacc
     8761 cagatttaaa agctaatgaa aattataagc aactaatgag tgagttgagt ataacagaaa
     8821 atatgattgc acaacataga gaaaattata atatgcaagt tcgcaattac aataaatata
     8881 taagaaaatt tccagcaaat ttaattctaa atagtatggg atatgaaaaa atagaatcta
     8941 aatatactga atataaagca aaagaggatg cacctcaaaa tttatttgat taagaggtgc
     9001 acatatgaaa tttaaaactt ttgaaataac taagagagaa tttttagtga gcataataat
     9061 tgcttgcatg atgattgtgc ttggattttt cattgatgat aaagttcaat caaaattttt
     9121 agaagataat gaaagatatt acaaagcaac taaaataaat aatgacaaag atctctttga
     9181 ttatgctatg gaaacaagtg cgggagattc tttgataagt ggaagattta aaagtgtaga
     9241 ttctgtatct atagaagaat taaaagggga ctattggttt atagaaagaa cggaagaaaa
     9301 atacactatg catactagag tggttaccac taaagacagt aaaggccatt cacataaata
     9361 tactgaaaca tattggactt gggattacca tgattcaata gagaaaaaat gtaataaatt
     9421 taatttcatg ggtaaagagt ttgatgcgaa agtaattact aatttatcta aagagagatt
     9481 ggcattaaag aaagatatat ttaaaaataa taatcttaaa ataaaaggta attatgctta
     9541 cattaataat aagagaaggt actattatga agttataccg aaagaattta atggtactat
     9601 gtatgctaat ttaaaaaata atactatagc gaatccagct gataaaaaca taaaagtttt
     9661 taagggtgag tctatacaga atgttttaga aaataataat tttaatacag ggttttttaa
     9721 agtagtgttt tggatcatct ggatattaat aactacaatc attatatatg tattttatta
     9781 tttaaaaaat gattggcttg aagataaata aagatgtaag aggagaagat caggtatgaa
     9841 atgtaaggtg taccatgcta ttaaaaatat aaaagatgca aatgagttaa ttgatagatt
     9901 tgaaacggaa aatatattct ttgaattaaa tgacatagat aatgaaaatg tcttaaatgg
     9961 agaaatgaat ttaactgata tagaagatat tgcatcattg caatttatat tagatggaga
    10021 tttatttata tttagtagtt gtgatgaaat gatatttatg aataaataca ctcaaaaaga
    10081 gttgggactt caataaatga atgaggggag atactaaaga tggatttaaa gttaattagc
    10141 agtataccta attggaaggt agaagatcag ttggcaaaaa ttgatgaaga ggtaactgag
    10201 tttaaaaatg ctatagatac aggaataact aaagatataa ttgcagaagg attagatgtt
    10261 tgtcaaacta ttttaacaat gtttcaagtt ttagaaatag aaaactatat tactgaagga
    10321 gtagagacac ataataagaa actaaatgga agaggatggg atctcaaaga aataggagac
    10381 gatatactta atttaattaa aaattcaatg attaatgaat tgattaatat gaacaagaaa
    10441 ttaaaatgcc ttgatgaaaa agaatttaat gcaaaaatac aatttttaga tgtagataaa
    10501 ctatggaatt tgtgcatgcc tttagttaac ttaagtacta taaaaggagt taatgaaagc
    10561 attgatgaaa tgaaaatggg agagtttcta aaaaatatta attaaagtaa ggagataata
    10621 taatatgttg atagaagtaa ctgaaaataa tagagaatta aaagtaggag atattgttga
    10681 aattaatggt ggtaataagt tatatatgat tctttcttta aaggaaacaa taggtgggta
    10741 tgttattata aatatgcaga atggatatgg ttcatttggt gcttataaaa gtttaagtca
    10801 actagaatta gacttgaagg taagaggtta taaattatat agttctgatg attacaagtt
    10861 gcaattagtg cctagagaat aagatatatt tcaaaaaaga aaaaaaggag cattacttca
    10921 cgctcctgct tgtcaaaatt ctaaaaccgt catcacaaca tcattataac ataattagga
    10981 gtgtgaggta atgcaatcta gtaaaaaaga caatttgttt agtagtgcag aaggtaagtt
    11041 atatgattat aaaaaaataa aagcggaaat agaaaaaata gacattgata tgcagatgat
    11101 aaaaaacgac tacagaggat gtagtggagt tgaaattaaa gaaaagacag gcaagacata
    11161 tgatattaaa agtgtaattg aaatagagac tgaagaaaaa gaaaagaaaa ttgccttaaa
    11221 agaaaaagag aagagacata aagagttgat aatagaaaaa atagataatg caatgaaaat
    11281 attaagtgaa gaagaaaaaa agatagtaca gtataaatac ttttcaagta gcaggacatc
    11341 ttgggaatat gttggcagaa tgattggttt ttcagcgagt aagtgtaagc aaatgaggtt
    11401 tgatattata gataagataa aaggattgct ataaaaatgt ccgatttgtg acgattttaa
    11461 accgatttat gtctgttttg tgtctaaaaa atgtccggtt tgtgaccaat ttatgtctgt
    11521 tttgtgtctt ttaatcatga taagattgta ttgtgagaaa aatatattta ataaaaatgg
    11581 cttggaattt acgttctaag tcttttttat tgtctagaga ggtgttgaag attaaacgtg
    11641 atataacaga agaaatttca agtgctgcat atgtaccaga caatctaaag tattacgaca
    11701 atgtaatgaa agaaactcct ggtatgtatg gaagagaatg ttctttagat tttataaaga
    11761 aaaagcaaga aaaactcttg aaactaaaaa agaaggttaa gaaaaattat gattctaata
    11821 ttaataagat agactcatat ctaaaaattt tagagaaaag tataattgat gagtctgatc
    11881 acgttgagtt ggttgtattt aaattatatt tgcaattaga aaatgttgta aaagtaactg
    11941 aaactgtaaa cgacttagga tttagaataa agactaacac ttatgcaaga gaaagaaaat
    12001 atagtacaaa tgatataacc tctataatca cagatccttt tactgatgta gttgaggact
    12061 taaaaatatt agttcaagag aggcaaagaa aaaattatta tggaaataag gagtgttttt
    12121 aatgaatgga agcacatagt ggacaaaagg ttaatcccat aaaagatata gaggatgtat
    12181 ttagactttt aaattttcta gaagaatgga atgaaagaaa ctatttatta gccctctttg
    12241 gaatgtgtac tggacttagg gtaggggata tattagcact taaagttgca gatgtaacag
    12301 acttaaaact cgataaaaaa ggaaataaaa taagagtatc taaggattgg attagagtta
    12361 tcgaagaaaa aagagactat aatagagagg tttttttatc tgatgtaata aaaagtgcta
    12421 tagaaaatta tactcaagat aaaccaggag aagaattttt atttaaaagt ggcaagagga
    12481 agaaatttaa tagacctatc caaacaagac aagcaggaag aataataaaa ggagcagcaa
    12541 aaaaggtagg aataaaagaa aatgttgcaa cacactcttt aagaaaaaca tttgcaaggc
    12601 atatttatga tgaagaagag aataagactt atgcattaga acttataagg aagattctag
    12661 gacataagac aatagaaatg actagaagat atataggaat agataaggat gaagaagtaa
    12721 aagcaataac taaatttact aataagttaa agaaaagaaa aagaaattaa aatatcttgt
    12781 attttatcta aaatttaata tgttacgttt ttcaacaaca ggacattatt agaatgcaaa
    12841 gagccttaac aatagagttt acaaggaata gaatagattt attaaaatgt ctgaaaatat
    12901 atattaaagg tcatttattc aagggattta tagggatgta gatatttaaa tgtttattta
    12961 gaagctgagt aaagaggtga ttaattggat gtgaatgaag ttgaaataat cgatagtagc
    13021 tatgaaaaag gtaaagagtt gacagaagat cagtgcaata tggtaactct attgattaca
    13081 ggtgctacag taacagaaac tgccagaatt attggagtaa atagaaaaac aatctataat
    13141 tggatgaata aagagcatgt taggaaagaa atggacagac ggaaacagga gctaacaaac
    13201 caaggaaatt taatgatatt aaaggattta gatagttata tcaacaatat caaggaatta
    13261 gctagtgaca agagcgataa gagggttatg ttggcagcca atcagtatct tataaatcgt
    13321 atatatggaa ctcctacaag tacagttata caagcagagg ataatagtgt tggcatgggt
    13381 atggatgcaa cagagataga agcagctata gctaagataa gaataagaac aagcaagaag
    13441 taattagata tgaaataaat cctgcaagaa tatgttttaa ttatgtttga aatcaattaa
    13501 agcaaaacat atattatata tatatttact ttaataatta aatcatatat tgtatttaac
    13561 tttagttata gctaatttaa taaaatttag tgagacttaa taattaaagt ttcatacagt
    13621 gaagtgatgt ggattattat aggatatgtg aacctattgg aaatgctagg ttctttttaa
    13681 ctatgccgaa aatacatatt taaggaatag ttgaaagata attaataatt ctaatcaaaa
    13741 aaatatttct tgcaagaaaa taattcaaaa tactttaata tatttatttt ttttattaat
    13801 agggggtgtc cttctatttt gaaaaaatta ttttttatgg aaaatgagtt ctagaaattt
    13861 tctagcaaaa tttaaaaacc agagatgtat ttcaaagagg gtgattttat tagagaaaaa
    13921 tttacattgt ttattttatt aattgcatta ctcactgagc ctaaaaaaat agaagaagta
    13981 agaggaagta aatacgagtg gataatctag aaagaaatat acaattaata tttagttatc
    14041 tagcaaagac ttttataaga aatggagcat ctataaaaga tgctgaaaaa gaagcaaatg
    14101 agattataaa agccaattca aacaatcttt ggggagttaa tggtctcgct tatcaacttg
    14161 gaaaaataaa cctagaattt ttctgtatgt attttatgca agacacatat ttaccaaaag
    14221 aagataatgc tgctgctcct atagctaaag ttcatcatga gctatgggaa gatatacaag
    14281 aatctataat tggagatggt tcacagcaat taggaagaat ttatccaaga gggacaggta
    14341 aaagtgcatt tggagattta gcgacaactg tatggtcgca ttgctataaa cataagacat
    14401 atactttgat ttgctctgac ataggatcta cagcagagaa atttgtaaaa gatataaaaa
    14461 atgcattact tgaaaatgag tatattaaaa aagcatttgg tgtcctttta aatgataatg
    14521 atagaaaata catttgtaat agtactcaac tagagctaac aaataaaact tttattgaag
    14581 ctatatcatc ttcatcaccc atgagaggaa gaaaatacaa taataaccgt ccagatctta
    14641 tcatacttga tgattatcag tcagaagaaa atgttagaac agaagatgct agagagaaaa
    14701 aatttaaaag attttctgat gatgtaaaat atgctgctca aaaaccagtc ataagaaatg
    14761 gtaaaactat aaaaagagga acaactttta tagcattagg aaccttacaa cacaaagaat
    14821 gtttttatag tagactaaaa aatttaccaa cttggaagtt taaatgcgaa aaaggagttt
    14881 tagttgataa tgtagatgaa ttatttaatt ctggtttatg gcttaagttc aaagagatct
    14941 tatttgattt taaaaataca aatcatcttg aagatgctaa agaattttac tgggaaaatg
    15001 aaaaagaaat gaaattccct atattatggc caagtttttg ggattgttta gatatggctc
    15061 taagttatta tgaaaatcca acatctttta agcaggaagt gcaaaatgat gtcaattcta
    15121 taggagaaaa atggtttaaa actgttagaa cagaaactag agaagaaatt gaatcgcata
    15181 cttttaaaaa gacaatgctg ttatgtgatc cagcatctgc gggtgggtcg aaacatgact
    15241 atagcgcttt tcttgttgga agtgaatcag aaaatggttt actatatgga agattggcag
    15301 aactagctaa aataaatgct agaactgatt ttgataaata tatagaccat atgatttatt
    15361 tattaaaagt gtattcagat ataacacata tttatataga aaaaaataca tttaatggcg
    15421 cagatgccaa ccaattagag tttaaaataa aaaatgataa tgttcttagt tatagagata
    15481 tagaaatcat taatgagcaa caaaagaaaa ataaagatga taaaatctct actttaatac
    15541 ctgttttaag caaaggccaa atgatttttg cagaagaaga taaggaattt atacagcaaa
    15601 tacttgattt tacaggacaa aaatactctc tacatgatga tgctccggat atatcatcgg
    15661 aatttattaa tcgaattaac aacataaaag tttctgagac agtaaatatc tttgatagaa
    15721 aattattagg tttttagttg ggaggtaatt tattggctaa tagatcaaag tttgaagaag
    15781 ttcaaaaaac tttaactaaa aaaggaaaga agttcaatgt tggaatagga aaagatgaaa
    15841 aaggatattt tgcatatact catagagcaa ggagtaaaag ttatatttca aagcaagata
    15901 ttccaataaa agttttaaaa tttatagagt ctacaggata ggatgtgttg ttaatggaat
    15961 tagatttaga cttaataaaa gacatatatg acgattggaa ctctaataaa tccgaatatg
    16021 atactatgta taagtattat aaaggtgaaa cggatgctat tagcaactat aaaatggtta
    16081 ccaagagatc taataataag ataaacacta atttcttaaa aaagtttatt aatgaagaag
    16141 tcgcttattc tcttgcaaat aagattacct atacaagtag atctggtgat gagaagatta
    16201 taaatgattt agaatactat acttgccatt ggagtaaaaa acatgactca gatttattga
    16261 ggtatgcact attatttggg ctttgctatg aactttacta tgtaaaagat gatgaaatac
    16321 aagtaaagat aatcaagcca acagatggct gtcattatga aaatgaaaat ggagaaatag
    16381 tatgctttat tagagagttt accaaaggtt tcgaagatga cacgtatgta gatgtatatg
    16441 acaaagaata tatatatcat tttgattcaa atttcaaaga agttgaaagt cctacagtaa
    16501 acaatatatt tgatggaaat gttccaatat caatttgcaa aagaagtgaa gaactaggaa
    16561 aaaatacaat atttaatgat ataaaagggt tacaagatgc ttatgaaact aatttaagtg
    16621 atataagtaa tgaaattagt gattttagaa atgcttattt aaccttttct ggatgtaata
    16681 ttaaagaaga tgatttgcca aggatgaaag aacttggaat acttcaagtt aatggagatg
    16741 gaaaaataga gtggcttatt aaagatatga atgatacatt tgttcaaaat acactatctt
    16801 caataaaaga aaatatgtat gaaattacat ctcatataaa tcacaatgaa aaaatgcaaa
    16861 gtaatacatc aagtctagca gttatagcaa gattaatcag tacagaatgg atttgtagcc
    16921 aaaataatga tagtattgca gatactttat ttaataggta caaattattg tgcatttggc
    16981 ttaataaaaa atatggtttt gactatgatt ataaagatat taaggctaaa tttaccccta
    17041 agataccacg tgatgattta gttgtagcaa atatattaag ccaacttgga gataaattat
    17101 ctactgaaac tggcttatct caactaagtt tcattgataa tcctcatgct gaaatagaaa
    17161 aagctaaaaa agaacaggaa atagtttcag agggagagat tttattagat gaatcaaaag
    17221 attataacta aattgactga agatatatat aaatctgctg aaaataggac aaaaccattt
    17281 tataagtatc aaagagaaaa tagggataaa cttttattag aaatagcaaa gatattgcta
    17341 acacacgata ttattaatga atacttaaat attaataata aagataagaa aaatctaagg
    17401 tcaaaactta ataaaattat aaatgagtat tctaatagtt atgatgaaga agtcaaggat
    17461 atagaaacta ttttatctga ttcatctaag aataaatatt caaatttgat aattttatta
    17521 ggagtaatac tgaagataaa agatgttagt aatataaaca ataaagttat aaataagata
    17581 gtgaataata aggttgatgg aaaacattgg agcgatagac tctggaagaa taaaaaaggt
    17641 atagaagagt ccttaaaaaa agaaataaag agttttctaa atggaaaaac ttctgtaaat
    17701 aagatagaaa aagcaataag agataaatat tcaacaggtg caggacaaac cagcagacta
    17761 atagaaaatg aagttgccag atgtcaaagt gaagtaaatg agtatttttt caaggttcaa
    17821 gggattataa aagtaatgta ttgtgcagat ttagattctc gcacatgtag tgattgttct
    17881 atgcataatg gagtgatatt ttatgtcaat gaagataggc cctctttgcc aagacactgt
    17941 cactgtagat gtcaatatat acctgtttaa catgtattaa ttaatttaat aggtgttttt
    18001 attatgtcta aaaaatatga ggtgaaatat gaaagttgaa atattaggaa cagaatatct
    18061 agtgatagag aaacttgaaa gcgaagatgt gctattaaag gaaagagctg gatattgtga
    18121 tcactctgtt aaggaaattg ttatagagaa aataaattct gaagaaggtt cattgaaaga
    18181 tttaagtgta tataaaaatg aagttgctag gcatgaaata attcatgcat ttcttagtga
    18241 aagtggattg aagagttgta gttcttgggc tacaaacgaa gaaatgattg acttctttgc
    18301 aattcaattt cctaaaatag taaaggttat ggataaaata gaatgtttga attaaatttt
    18361 caaaaaggag aactttatac atgttaaaaa aagaagtgtt ggaattacta aaagaaatag
    18421 aagatgatgc agaaatagat tcattgctgc aatcaacaga tttattcaaa tctgcatctg
    18481 ataaaaagct tacaatagaa gagtttagag aattaattaa taatgatgca aactttaaag
    18541 ctattataga taatgaaaaa aataaatatc acagcgaagc acttgaaaac tttaagaaaa
    18601 aagatatgca gacacttata agtgctgaag ttctaaaaag aactggagca aatgaaacag
    18661 aagagcaaaa agcaataagg gaattaagag aaagcctaga caaactaaaa aaagaaaagc
    18721 agtacgcaga aaaagtttct aaatataaag atattttagt tgaaaagaaa atacctacaa
    18781 acttaattga atatctatta tctgatgatg atgataaaac aaatgcaaat atagagatat
    18841 ttgaaaattc aatgaagcaa tatgtgcagt caaaggtaga tgaaagaatt aaagatggtt
    18901 catacgttcc acctggcaaa gatagtgcag gttcgctatc agaaattaga aaacaaataa
    18961 agcaagggct aaatagtctt tagtataaaa aaagaaagga tgattttata aatggctaat
    19021 gtattacaat atgtaacact ttttcaacaa gaactagata tgcaggtaac agttggctca
    19081 actactggat ggatggagaa aaatgctggt caagttatat ataatggagg aagagaggta
    19141 aaagtaccaa aagtaacaat ggatggctta ggtgattatg acagatctaa aggatatacg
    19201 caaggcgcag ttacacttga gtacgaaaca atgaaaatgg agatggatag aggtaggact
    19261 tttatgttag attcaatgga tgtaaatgaa agtaacttcg ttataaatgc atcttctgta
    19321 atgggattat ttcaaaagca acatgttata ccagaaatag atgcatatag atactcaaag
    19381 atattttctg aaacagctaa agtagatgag cgtgtaaaat attcatacga agctacagta
    19441 actacaatat taagtgaatt gaaaaatcaa cttgcatcaa tacaagattt atctggagat
    19501 atacctctta ttattagtat gtctagcata attgcaagca tattagaaca atcatctcaa
    19561 cttgatgata ttgaatttgg cgatggagat ataaaaagaa ttgtaaagtc tatagacaat
    19621 gtacctataa taaaagttcc atcaaaaaga atgaaaacag aatacgtatt tagagatggt
    19681 aaaacatctg gacaaacaga gggtgggttt actgaaggag caaaggcttt agatataaac
    19741 tggttaataa ctccagcatc tgctccaatt gcagtatcta agactgataa gccaagaata
    19801 tttactccag atcaaaacca aacagcagat gcttatcaaa tagactatag aaaatatcac
    19861 gatttgtgga tattggatga atatttaaaa ctttgtagag catctgtgag acaagctaaa
    19921 gctgcacaag aataaggagt tgttttaaat gtttgcattg ataaaaaata acataattaa
    19981 agttgttgaa gatgaaaatt cgagagataa attgatttca aaaggattta aaatatattc
    20041 agaagaagtg actaaagaga atattgagaa aaaagaagaa aaagttaaat caacctctaa
    20101 tgatttattt aatctatcta aaccagagct tatggaaatt gctaaaggca agaatataaa
    20161 gggatattca actaaaacta aagaggaatt aattcaacta ctagatgagt acaatgcttg
    20221 ataatgttaa attagtttta ggaatagaaa atgatagata tgacaaatta ataatccttt
    20281 atataaataa aataagtgag atggttttag aatattgttc taggcaggaa ctaagtacag
    20341 cactagaagg gtttgtagaa gaaaaagtaa tatcaatatt atcttcaaga tttgaagaac
    20401 ttaagaaaaa tagtggactt gataatctag aaaaaagctt aaaagctata actagaggtg
    20461 acactaagat agaatataat gctttaacat tacaaactgc tgaaaatagc atcagttcat
    20521 catctttttt aactgatact gataaaaaat ttctaagccc attttgtatt gttagtatgt
    20581 actaaggggt gattaaatga ctgaagcaga tatattagaa atgacatacc ttgataaaat
    20641 gactataatt agaaaattaa aaggctggaa tgaagaaaca tgttctaatg attttagtaa
    20701 tgttgttata gctgaaaata tcccatgtgc aatttctaga aaagaagaag ccattgtaaa
    20761 tggtgatatt ggatctatag ttgtaaatag aaagttattt tgtagaccag aagtagatat
    20821 aaaaataggt gatactataa atacaaccta taatcatgga gaagaagctg tatttaaggt
    20881 ttctaaggca aatatatatc caagccatat ggaaatacct attacagaat tggagaggat
    20941 ataatgggaa tagataattt aggagtcttt gaagcattag ccttagattt aggtctaaat
    21001 gcatcaaact ttaatagaaa aatcaagaag tttacaaaag aaactgggca agaactagca
    21061 gaaaatataa gagatgaaac tcctgtaaaa actgaaaagt taaaaaaggg atgggaagaa
    21121 aagcaaccag aatatgatac ttatattgtt aaaaatgaag ttgattatgc tactttagta
    21181 aataatggcc attcaactaa aaatggtggc attgtccctg gttcttttat ggttgaaaag
    21241 ggaattgaaa gaacaaaaga aaatatgaca agtgcaaaag caaatttatt tgattggtag
    21301 gtgattagtt gcttacaaac agagacatta taatagcagt taataaaaga atcgaaaatg
    21361 agtttagata tatagatatt tttattaatg aggataatat acaaggcttt gaggaggctt
    21421 gtttttttgt gcaactttta cctgtttcta ataatattgc aaataaagtt ttagatacta
    21481 aaaagatatt catagatatt gaatattacc aaaaggctag aaaaaataaa ttaaatctat
    21541 acgacataca aagtagatta gaaaaaatat ttaacagaaa cattagagtt aaagatagaa
    21601 gtttaatcat tgagaatata tctccatcaa tcgcaaaaga tcctgtagga tataaactaa
    21661 cttttctaat gactgtatct tattttgaag aagtctattt tgaaaatgaa acatttgaaa
    21721 ttatggaaag tgtagattta gagataggaa gtgattaaat gggtttacca gaaattaata
    21781 tttcttttat ccaagcagga aaaacttttg ttaaacgctc tggtggtatt gtagcgctta
    21841 ttttaaaaga tacaaaaaat atagggttag ttgagataaa agaaatagag gatattccag
    21901 aaaattattc tgctgctaat ttagattata taaaaatggc tatgaaggga aatgtatatc
    21961 ctccaaataa agtattagtt tatacattag atacagatga atcaatagat gatgcactag
    22021 attttcttga aacttgtgag tttaattatc tttgtatgcc agatgagaca gaacaagatt
    22081 tgcctaaaat caaaacgtgg attaagaaaa tgagagaaga taataaaata aaggttaaag
    22141 ctattactgc aagtaattca gcggattatg aaggtataat aaactttaca gcaactgata
    22201 ttgaagttga aggtaaaaaa tacacttcaa atgaatttct gccaagaata gcaggtttta
    22261 ttgcaggaac tccatcaact caatctgtaa catatgcaga aataccagaa gttactaata
    22321 tacctaagct aacaagagct gaagcaaata caaggataaa taatggagag ctaattttaa
    22381 taaaagaaag tggagctata gtaatcgcta gaggagttac atcctttaca acaattactg
    22441 attcaaaagg tgatatattc aaaaagatta agttggttga tacactagat caaattcata
    22501 acgatattaa aaaaataatt gtaaaaaatt atataggaaa aacccaaaac acttatgata
    22561 ataagtgttt acttattgtt gcaatacaat tatatcttca agaattagaa aaagatggtt
    22621 taattgatga aggttcaact gtagaaatta atttagatgc tcaaagagca tggctaaaaa
    22681 aacaaaatat agatatatct aatatggaag aacaacagat aaaagaatac aatactgaca
    22741 ctcttgtatt tttaaaagca agaattaaat taatagatgc aatggaagat gtatatttag
    22801 acatctctat gtagtttgga ggttaaaatt tgaaagctaa aatagatgca aaaagaataa
    22861 tatctggtac ttttggagag tgttggctag ataataagca acttacatca acaaaaggga
    22921 tggaggccaa ggttgatata gataaagaag aaataaaatt atgtggtcaa ataatgacca
    22981 catataaaat gattggtgca actggaaaag gatctataac tctttataag ataagtacct
    23041 tatttggcga gtatgtcgaa aaaatgttaa atgaaggtaa agaatttaaa gtaactataa
    23101 taagtaaatt gcaagaccca gattcatatg gttctgagag aattgcactt tatggatgta
    23161 tgtttgacga cttaactttg gctgattggg aagctgcgaa agttggagaa atagaagttc
    23221 cattcacatt tgaaggcttt gaatacttag ataaaataaa agaaaaatag gaggatttta
    23281 ttatatgaac acagtagaaa aattattaaa tatggatgca ggtaaattaa aaatgccatc
    23341 tagcgcattt gaattatatt gtaaaaaact agatgatact ttagaaatag agtgcaaggc
    23401 tattgatcca gaacgttttg acgaaataag aatgaactct atggacgtta atagtggaga
    23461 tgtagaaaac attaacatat atgaacttaa agtaaataca atattagaat catgttctat
    23521 atttagcaat atggaattag ttaaaaaatt tagtgcaatt acacctaaag aattaattaa
    23581 aaagctatta cttagtggtg aaatagataa attatacgag gaggttaata aagtaaatgg
    23641 aatagatgca gagggagata aaaaaagaca aaaagaaaga gctaaagata taaaaaacta
    23701 attaaaacgg atggagaagt taacttgatg tacttattat ttaagtataa aggtataatg
    23761 ccatccgttt cttatcatat actaagaggc gaaaaagaaa ttgttagtgt ttttatggat
    23821 caagaattag atgaaagaaa agaagaaata aaatctggtg ttgggaggtt gttttagtat
    23881 atgagttcta atacaaaggt cctacaagca ataataaaaa tgagagatga agcaagttca
    23941 acattaaaaa gagtagcagc aaatactaga gctctacatg attcatcttc ccaagcatca
    24001 agagcattaa ataatgttca aagtaattta aaaagtgttg gaactagtgc tttaaaagca
    24061 ggaggtctta tcactgctgg agttggtggt gcatttgcag ctgcaactaa agttggaaca
    24121 gaatttgaaa gcgctatgtc gcaagttaag gctacatttg gaaattcctt aaaaccagga
    24181 gattttgaag ctctgtctaa ggctgctaga gatgctggaa aagctacaac taaaactgct
    24241 gctgattctg ctaatgcact tcagtatatg gggcttgctg gatgggatgt tcaaaagtca
    24301 atgcatgcct taatgccagt gcttaattta tcagaagcag cctctatgga tcttggtcta
    24361 gcatcagatt tagtaactga tagcatgagt tccatgtgct tagaagttga taaggtcagt
    24421 aaaagtggaa aagtactagc tggtgcaggt ttaagtgagt atttagataa agttgcaaat
    24481 gcatctacta aatcaaatac aagtatacaa cagttgatgg aagcgtttaa tgtcgcaggt
    24541 ggtacattta gcaatttaaa agttccactt tcagaagcaa ctgctatcat gggaatactt
    24601 gcaaatagag gagttaaggg tacagatgca gggcatgctt taaactctat catggtaaat
    24661 cttacaacag gtgcaggtca agcaggtaag gcaatgaaaa agttaggtgt aagtgcattt
    24721 gataatcaag gtaaatttaa aggtatgtca aatgtgctta aagaggttgc aaataaaact
    24781 aaaggtatga ctgatgaaca gaaaaattat tacttatctg ctattggtgg aaagactcaa
    24841 ttaaaaacgt tacaaaagtt acttgatggt gtgggaaatg aatatgatag cttaaagaaa
    24901 aaaatagata attcaaaagg tgctttaaaa acaatgtctg atgtaatgaa ggataatact
    24961 aagggtggac ttgcaacctt aaaatcagcc cttgaagaaa ctggaattac tatttactat
    25021 caactaaagc cagcaatagc atctgtagtt gataatttaa ctaaaatgac tgtttggttt
    25081 aataatctaa gtgaaccaat aaaaagagtc ataactaatg taatgctttc agttggagca
    25141 tttggagtac ttttattaac tataggggct gtgtctttaa ttgtttcaaa agctataggt
    25201 atatttggct tttttgttcc aataatatta agagcaaaag ttgctttcag agcttttgta
    25261 attggtatga aaccattaag tgcagtattt ttagctgtaa tgggtcctgt gggatggact
    25321 ataacagctg taattgcatt atcagtagca tttaccattg cttatgctaa atctgaagta
    25381 tttagaaata aggttaattc attagtaaaa tcatttacag aatttgcaaa gcctatagta
    25441 aatttttgta tgcctgcact taaacagcta ggagagaaat ttaaagagtt gttatcagca
    25501 tttggtccac tatttgcatc tattttaaac ctaggaagtg taataatgaa ggtactagga
    25561 cctgttttaa tcggcgtaat aggttttcat atagcaaaat tagttttgat tttatctact
    25621 ctggcaactg cttttaaagc tgtagttgat actataacta atgtattaaa tggtctagca
    25681 tctattttaa atggagtatt tgatttaatt ataggtattg tcacaggcga tagtaaaaag
    25741 atgatggatg gagttaaaca aatatttgat ggtggaacta aaattataaa atcaatttgg
    25801 aaaggtttca tagattttgt aactgctcct atacaagcta tagctgatat agctgacagc
    25861 ttatttaaag ataaagctaa atggcttaca gataagtgga gagatttaag aacattctta
    25921 gaaaatccaa ttgaagcaac tgccaaaata tctactaaaa caaatgtaaa tatcccagga
    25981 agtaaagcag cagatgcagc tggtaaatct acaccaaata caggtggatt aaaacaaaca
    26041 gtagcaaatc taaaaggttc atttagtgat tttaaaactt ttattaagcc tatgacagac
    26101 tctataagtc aaggagttga atctggaaaa actaaattta cagaactgca aaataaaata
    26161 ttaaatgatg ttaaacctgc actaaaggtc ctagaggatt ctggagtaaa ttttaaggat
    26221 aagtttaagg agtcaataac ttcaataaaa gataaattta atgaattaaa gaacatatta
    26281 gctggaaata ttaaaacaaa tatagataat ttagtaaaag catttgaacc tttaaaacct
    26341 catttagata atttgaaaga ttgctttgat aaggttaaaa aagcgattac tgattttttt
    26401 actccagcca aacaggttgg agatacagta aacaaagtaa gccaaccaat ggatagtgtt
    26461 aaaaagtcta ctgatggaat taaactttct ttccaaagtt taactcaagc acttgctcct
    26521 gttaaagctt ggtttcaagg atttatgcct ttcctatcac aaataggaca acaactttta
    26581 ccatctatag gaattgcaat agctggtgtt gttggcggaa taattttagc atttacatgg
    26641 gttttaaata cattgaccgc aataataaca acagtatctg gaatcataaa tggaattatg
    26701 tcttttatat ctggaattat taatgttatt atggggctta taacaggaaa tgctgatcaa
    26761 actatggatg gacttaaaca aatatttgat agtggagtag gtgtaataaa atcaatttgg
    26821 aatggccttg ttgatctagt tagtggcgta ctagaacctg taatagatct tgctgattct
    26881 cttttcaaag ataaagttaa aggggtaaaa gaagcttgga ataaacttaa agatttcttt
    26941 aaacatccaa ttaagggaac aatagaaata tttaaaaaag gtcctagttt acaaattgga
    27001 aaaggtgcag atgctgctgg caaaagtcca agaaaagcat ttggtataaa tagagttcct
    27061 agaaatgatt atttaataag agcacacgaa ggcgagaaac ttttaaccaa acaagaagct
    27121 aatcaataca aaaggaatag ttcaaatgga agtttatttc ttgataaatt ggctgataca
    27181 ataattgtaa gagaagaggc tgacatagat aaaattgtaa gaaaaataaa caaaaaaata
    27241 tctcttgcaa aaattggagg tgttttgtaa attatcgtgc tataattgta gtatataatt
    27301 tacagggggt tatgttatga ataaaaaaat actagtatta acaatatcaa ttatactatc
    27361 tttaagttta gttggatgca gcacaaataa ttcaaaaaat agagatagta aatctaagca
    27421 aaacacagag gaagttaaaa atcataaaat aggcgaagtt gttgatttag atggagcaaa
    27481 agtatctgtt aaaaatatta ggaaattaga aacaaatagt aatgattatg ctgttgaaat
    27541 tgaaataact aatacaggtg ataatgattt acaaagtgat tatctagaaa actatatatt
    27601 aaaatcaagt gacaatacta ctggagaagc aataaataac caagaattaa atggagagtt
    27661 aatgtttgat acaatacgcc caggagatac tttgaaaggt gaaatagcat tcgaacttac
    27721 aaaagatgca acaccaaaaa cacttgaaat tgcttatgaa aatgtaggca aatatacagt
    27781 atttgattta tagtaattat cttaaaagac gcttatttac ttaagtgtct tttattttag
    27841 gaggagttta atggaaatat ggttaagaca agcaaataat acatttaggt ttcctgttat
    27901 tccaccctct tttgagataa atggaagtgc gacaataaat acatctaata ttttaagtgt
    27961 tggagatatc gcagtatttg gaggattagg gcttaaaact atagaactat cctctttttt
    28021 ccctaatcaa gaatatagtt tctgtaatta taatggattt ccaaaaccat atgattgtgt
    28081 aaatttaata gaaagttgga tgaaagaagg atatatatta agatttatca ttacggaaac
    28141 taatataaac tttgaatgta taattgcaga ttttaattat agagaacaag attattcaag
    28201 agatatttat tttaccttaa gtctaaaaga atacagaagg atacaaatat ccaaagtaaa
    28261 cattaataat gatgaaaaat tatcttctga aaagaatgtt cctctaacaa aaggatttga
    28321 tactaagcaa aaaacgcata aggttgttga aggagatact ctttttaaga tagctaaaaa
    28381 atattatagc aatggagatt tatgggagaa gatttataaa gcaaatgaag atgagattaa
    28441 agatccatct gtaataaaaa atggttgggt attaataatt ccttaaaaat ggtggtgatt
    28501 tataattaat aaaatcaaaa tacaagttca tataaaaaac ggaaatatat ataatgtaac
    28561 tgatttagtg gataaatgca cttggtctgg tgattataga tcaccatcaa gaactttgga
    28621 attttctata attcaatctg caagtgatat taattttagg cagatagata ttccagtagc
    28681 aagtacagtt tgtttctatg tagatgataa agaacttttt agaggaatga taatagatag
    28741 atctaaagac tctagcaata ataatataga ttttacagct aaagatatgg gttttttact
    28801 tttacaaagc gaagtgtcat acaattttaa agataaatta gtcgaagata ttgcaaaaca
    28861 ggtttttgta gataataaat tcccactagg taatttacct aaaactaacg ttaaatatac
    28921 aaaaatgttt attggtgtaa ctggctacga tactataatg agcgtttata cagaagcaag
    28981 caagacaact aaaaaaaagt atatgataga gtctaatctt gataaattta atgttattga
    29041 gaagggtgta gttactttaa atataacatt tgaagaaggc tttaatctta tcaatacaaa
    29101 tttttctgaa agcattgaga atgtaaaaaa taaagtacta gttgttgatc agtatggtaa
    29161 taaaattagt gagaaaataa atgactctat atttaaagac gttggggtaa ttatgcaaaa
    29221 ggtaatacaa caacaagaaa acagtactat agacatagat ggagagttta aaggaatcga
    29281 aaaaacttgc tctttaaaag gatatggtga tataacttgt gtaactggta gaggtgtaaa
    29341 agtaaaagac tcatatacaa aattaatagg tcttttttat atagatacag ataagcatac
    29401 atggcaaaat ggagattatc aaattgaact agagcttaat tttgagaata taatggatga
    29461 aaaatctgct ggccaagatg agcaaaaaga agatggttca gagtatactg gaggaacaga
    29521 ataccctgct gaatttacgg cttattgtcc tagaaaagaa gagggtggaa atacagattg
    29581 tagaggtaaa aaactagatc cttctaaaaa gacatgtgcc gctcctatgg ttggagcata
    29641 tgaaaaatct tactatacaa aagatttctt aaacaaacat cctcttatga gatatggaga
    29701 tgaaatacaa ttagttacag gtgtttcaag ccgagatgga acgtataaag taaatgataa
    29761 tgggcctgca ataattatag aaaaggatgg aacatatcat atagatattt tatttggaaa
    29821 tgttgaagaa gctaataact ttggaagaag aaaaggaaag attataattg gtggttattc
    29881 tggaaacatg acagaaaaag caaaaacagt aatttcagaa gcaagaaaac atcttggaaa
    29941 gccatacaaa tggggtggga atggaccaag tagctttgat tgttctggac taatggtata
    30001 ttgctttaag aaggttaatg ttaatttacc aagaacctca agtcagcaat ctaaggtagg
    30061 taagaaagta gagaaaaata atttacaggc aggagatttg gtatttttcc ataatccagt
    30121 cagccatgtt ggactatatg taggtaatgg agaattttta catgcgccac aaacaggaga
    30181 tgtagttaaa ataagtaaat taagtaatag aaaagatttt aatacagcta gaagagtttt
    30241 gtaaaagagg tgatatcgtg gcagatccaa tcaatgaatt tataggaata attaggcaag
    30301 aaggtaaatt tcataatgaa ccttcttttt ttattggaaa aattaaaagt aaattaccag
    30361 atttaaaaat agagataaat aacatcatat tagaaaaaga agatattttg atagatagtt
    30421 ggatgcttga tagacagata gagttatttg atacagaaac aagtcaagaa cataaacatg
    30481 aaataaaaaa tccctttata gatacttttg aatctggaaa cacagtaata atgtttaaaa
    30541 taggtgaaaa atttgctgtt gtaagtaaat tggtgagtct agatgaataa tactatattc
    30601 cctttcatgg gtgttccaga agattatatt tctccagaca atgaagaatt acctattttt
    30661 aaagaatttg cttgggattt taataaagat gaaaagataa ttgaaaatgg agactttaaa
    30721 atagttgaaa gaaatgaagc aattaaagta tggatttaca aaacaataaa aacagataag
    30781 tatgttcatt taatatatga ttggagttat ggaacagata taaaaaatct aatagggcaa
    30841 aagtatacta aaggtcttac tgaaagtgag gcaaaaaggt atatacaaga agctctatta
    30901 actaatccat atatattaga agtcaatata acaaatgcag aatttgaaga tgataattta
    30961 tctataagtt taaatgtaaa aacaatttat ggagaggagg agattacttt tgtataatgg
    31021 ccaatcattc agtaccttaa ataatagaac tttaaataac ataaatctcc ctctttataa
    31081 aggccaagga tcttctcttt ataatatagt ttctccaata aattcagaac ttgcacaatt
    31141 atatatagaa ctttcttata tacataagag agtttttatt caagataatt ttgacgattt
    31201 tcttgataga agagtcaatg aatttggcgt atatagaaaa ttaggtacag aggcaatagg
    31261 tgaggtaaca tttgagggca aaattggaac tcaaatacca aatggaacaa taatatctca
    31321 tagtgattta ctatttgtaa ttattaaaga tattacaata gatgaaaata gtaaattaaa
    31381 tgtaagccct atacaggctt tagagattgg cattaagtat aatttatcag ctaacacaga
    31441 atttaaactt atagaagaaa taactggagt aactaaaatt tataatgaac ttgacctaaa
    31501 gggtggaaca gaaatagaaa ctgatgaaga attaaaagaa aggttctata aaatacaaaa
    31561 aaatcaagcg acaagtggaa ataaggcgca ttaccaatct tgggctttag aggttgaagg
    31621 tgtttataat gcaaaagtaa ttcctcgttg ggatggtcca ggtacaatta aaattctaat
    31681 ttatggtcaa aacaatcaat cagttgacaa tgaagtattg caaagatgta ctgaacatat
    31741 agaagaagaa aaacctattg gacctactgt tacaattgtt acaccaagta cttttgatat
    31801 taatattagt gcaactttaa cacttgaaaa tggatatgat attgaatcta taaaagttgt
    31861 gtttttagat attataaatt cttatttgat agaaaattca agagagattg tttatataaa
    31921 agtaatgagt ttgttagcaa gcatagaagg tattcatgat ataaaaaatc tccttgtaaa
    31981 tggtgatgtt aaaaacataa tagttgatga agaaaaagtt cctgctgttt caagtgctat
    32041 atttgatatc gaggtgagtt aaattgaagt taattgatta cctgccaagt tttgcaaaca
    32101 atgaaattga catacaaatc caagaagcac ttgaaaatga acttttaacg ctaattgatg
    32161 aaaaagatga tttattagaa cagtttttta tagatacagc aacttgggga cttgatgatt
    32221 gggagaacct tttaagcata aaagtaaatt ataagttaga cttcgatact agaagaagca
    32281 atataaaagc aaagatgaga ggtaagggta caacaacaat agaggttata aaagctatct
    32341 cggaagctta cacaaagacc aatgttgatg tagaagtatt tagtaatcta tttagtttta
    32401 cacttagttt tataacaaat aattgtagtt ataacactat tttagaatta gataagaaaa
    32461 tagaagaaat aaaacctgca caccttgaac acaaattcga gaggatatta tttaataaaa
    32521 acgagcttta tacaggtgca gcaattagta caggagaaac agttacaata tatccttatg
    32581 tacctagaaa tttagaaagt tttggagaaa tagctatttg tagtggaaat gatagagcat
    32641 tagaaaaagt aacattgtat cctaaaaaat agaaatgagg tgataaaatt gacagaacaa
    32701 caatatttta ctctagtaac tgacattggt aaggcagcaa tagcaaatgc aagtattaca
    32761 ggtgaaaaag tagattttgc aaagataaaa gttggagatg gaggagggag ttcttatact
    32821 ccaaatgaga gtcagacagc actaaaaaat gtggtttggg aaagtacact tgaacatgca
    32881 caaggagata aagataatcc taactgggta gtaatacaaa aattcatacc tggtgatgtt
    32941 ggaggatttg aaataagaga agttggtcta tttgattcta aagaccaatt attagcgatt
    33001 tctagttacc caacaacata taaacctact gcggattcag ggactgtaaa agaactatta
    33061 ataaaagtaa tattagttgt atctaatgta gctaatatta atttgaaagt agacccaacc
    33121 gtaattttag caactttaaa agatatacaa gaattagaca ctaaaataga tacaactaaa
    33181 acagaattaa caagcaacat agaaactgct aaaacagagt tgaacactaa aataggagat
    33241 acaacacaac ttactacaac agataaaaca aatatcgtta gtgcattaaa tgaggtaaaa
    33301 actagtgtag atagtataga aacaacagca gataaaacaa gtataaaaga tacagataat
    33361 ttatttgaga gcgacaacgt agagggagca ttaaaagaag tgatgcaaga agtaaaaggt
    33421 aatagaagca gtattatatc aacaataaat agtaatttaa taccaatgta gaaagtgagg
    33481 tgataaagtg aagatatgga aatacaatag aactgtgaag aaaagaagag gtgtctatac
    33541 agaattagat atacttgcac aaaggtatga atttgaagca gatgggaaac tttatacagc
    33601 ttattttcat ttatatacta ataagaatat agatatattc agagataaag atttatataa
    33661 agaatcttat atgatgagct atagagttgg aaatgtaaca actgatattg atgatgtagt
    33721 acagcaaaca actacagtaa gatttatacc tgaccctgtt attgatattg tgattgataa
    33781 cattagcaga ggatgtgaaa taaactacag aattatagat aatgaaccaa gtgtaaaatt
    33841 cattgttaca gaaaagttaa atggcacaat aatagaaaca aagacaaatt ctagtgataa
    33901 taattataaa cttaaattaa ctgatgaaca aatagtacca ttagcattca attcccaaaa
    33961 ttcaatagta atagaaataa gtacagaaga tggtggatta gtaacaagta aaacagtaac
    34021 atttacaaga acaaataaca agccaacaat tttagttaat tcatatagtt ctaattctgc
    34081 aaaatttaca gcatctgatt tagataataa tttaagtaaa attgagtggt atttagatga
    34141 tgtattaaaa gaaacaataa caacagattt aacagcagaa aaaaccatca actatgaatt
    34201 tacagacaat gcaatacaca cattaaaaat agttgctaca gatgcagaaa atgcaacagt
    34261 tgagaaggtt ttaagtataa gtaaagagat aatgccactt caatctgatg ctagtttaag
    34321 tgatatatca actaagctga tagagattgg agaagggttt agaaatggta aaacaagtat
    34381 tataaacact ttagcactta aaaatataga agcaagttta aataatacac ttgtggagtt
    34441 atcagagaaa ataaaaacaa gttttgatag ttcagacgct agtgtgcagg atttgcaaaa
    34501 tagaataaca gaattgaata atcagcttag tcgaagaaaa aaatgggcta caggtagata
    34561 cacatttact agagaagaag atactatcaa tttcagaatg gttgatggag atagtctttc
    34621 cgcagtaaaa aaactaatta tacccattaa tttagatttt gttccaagtg ttattataat
    34681 agacaaaatg tttttaggta gttacgtacc tgcacaagat gtgcaattta attgtgtttc
    34741 aaacttagcc gattttacac ttggacgtcg tttctataat aaacaatgga tttgcacttc
    34801 ttctataaaa ctagattcag ttacacaaaa tagttttact ctttctttac aaaaagttgt
    34861 tccatttgat aaagttagta gtacgatttt ttctattatt aatactggtt ttgcttggag
    34921 agcatatgaa taaaaatata aattagaggt gattaaatga atagaaataa tagaataatt
    34981 tacgaccaaa caggcaagat atggcttcaa actggtgaag caataggaga tatacaagag
    35041 ttgtcagaaa taactgaatt aaatttcata gatgttgaat ttggtagtat agactatagt
    35101 aaacaatata tagagtctat aaatccagtt acaaaagaat taaatataaa aaatatagaa
    35161 gttgttttga ctgatgaaca aaagagatta gaagtattag aaaaagaact aaatatgtta
    35221 aaagaagaaa ataaaaatag agattctgag atagtaaata cagcatttga agtaggaaat
    35281 atcaaattaa acaataattt ataggaggaa attatatgta taacttatta aagttaatga
    35341 tagaacaaaa aaactatagc actaaggagg atttacaaca taagatggat gtattctatg
    35401 cagtaaatag gattacagaa gaacaatatt tagagttaac aggtttatta aataaagaag
    35461 aaacaccagt agaaccaaca atataggttc ttttttattg aaagaaggtg actaaatgac
    35521 ttttaaagaa ttagttagta aagttagaaa tcttgtatta gaagcaaaga atgtaactat
    35581 agaagataca gagaataaat tcactagtga aaatgtcgag ggagcattga aagagtgtat
    35641 agatagagca gatttggctt ttcaaagtgc cgatagtgga aaagagttaa ttgcaactgc
    35701 tatcggctct cctgctacat ccgaacaaac atttcaagag tatgctaatt atattgcagg
    35761 atttaaaaat actataagtc agttaaattc taaatataaa tatactagtg gaacttttac
    35821 ctattatact ggtgcatatc ctaatgggct aaatataggt tttagaccag atattatttc
    35881 ctatactgcc attaatgctg tagaggaaaa atattattgt gtatacacac ctttattcta
    35941 tcttttttat aattatacaa ctggagaaaa atatcttgat gttaatcata atcgttatgg
    36001 aataactttt actgacaatg gatggatacc tagaaatcca gttaacaatg gtgtgtatag
    36061 ttatatagca gctaagtgcc gttagttgtc aaagacttag ataaatttct aagtcttatt
    36121 ttaatacaaa attaggagga agtatgaacg taacaatagt ttttttagca acaaatatat
    36181 ttataaaatt agtaatatta gcaatagcat ttgatacatt gctaggttgt ctaagagcaa
    36241 taaaaacaca tcagtttaat agctcttttg gaataaatgg aggaataaga aaagttgcaa
    36301 tgatagcatg tatatttttt ctagcagtag ttgacatact tacaaagttt aactttttat
    36361 ttatgttgcc acaagattgg gttgatttct tacgactaaa tcatctagga atatctgaat
    36421 ttttctctat tttattcatt ctatatgaaa gtgtaagtat attaaaaaat atgtatttat
    36481 gtggattacc agttcctaaa cgattaaaag agaaaatagg tagtttatta gatactatga
    36541 cagatgaatt aaatgttaaa ggaggaaaat aaataatgaa aatatgtatt acagtaggac
    36601 acagtatttt aaaaagtgga gcatgtactt ctgctgatgg agtagttaac gagtatcaat
    36661 acaataaatc tcttgcacca gtattagcag atatatttag aaaagaaggg cataaggtag
    36721 atgtaataat atgcccagaa aagcagttta aaactaagag tgaggaaaag tcttataaaa
    36781 tacctagagt taatgctgga ggatatgact tactcataga actacattta aatgcaagtg
    36841 ataggcaagg aaaaggctca gaggttctat attacagtaa taaaggtcta gagtatgcaa
    36901 ctagaatatg taagaaacta ggtacagtat ttaaaaatag aggagctaaa ttagataaaa
    36961 gtttatatat tttaaacagt tctaaaccca ctgcaatact aattgaaagt ttcttttgtg
    37021 ataacaagga ggattatgag aaggctaaga aacttggata tgaaggtatg gctaagttaa
    37081 ttgtagaagg tgtattaaat aagagtattg aaagtaatga ggtgaagcaa atgtataaac
    37141 acacaatagt gtacagtggt gatgatagag tatcagcaga tattttagga ttatattata
    37201 agagagcaaa agaaagttat ctagttatag atataaaaga ctataaacca catagaacac
    37261 aaaatctata tgtaattggt ggagtaactt gtaataaaat gaaagaaatg agtaagacta
    37321 caggagaaaa atttactcaa ctatatggta atgatgtatg gtcaacaatg gataaagtta
    37381 tagaatttgt aaaagaaaaa ttataaatta aaagacaacc tttaaaaatt aattgttaat
    37441 aaaactaata aaattttcaa ctcagaagga gcattatatg ttaacatttt tagatttgtt
    37501 tgctggcatt ggaggtttta ggctagcaat ggaaagagca ggacacaaat gcgtaggcca
    37561 ttgcgaatac gataaatttg caaacttaag ttacaaagca atgcataacc caaaggagga
    37621 tgaatggttt gaaaaagaca ttagagaaat tagagcagaa aatattccca aagcagatgt
    37681 gtggtgtttt ggattcccat gtcaagacat tagcattgca gggaacaaac ttggattcaa
    37741 aggaaatcgt tcaagtttat ttttctcagt tacaaaactt attagagaac ttaaagaaga
    37801 agatagaccc aagtacttac ttattgagaa cgttaaaaat ctacttagtg ttaatagagg
    37861 atttgacttc gccaaacttc tcattgagtt ggatgaaatc ggctacaatg cagaatggca
    37921 aaatctcaat tctaaaaact tcagagttcc ccaaaacaga gacagaatat acattgttgg
    37981 acatcttaga agaagaagta caagagaagt atttcctatc acaggaacga gtagaaaaac
    38041 tactcttgag caattaaata atcctaatca cagttcaaac aggatttata attcaaatgg
    38101 attatcaaag tgtttattaa gtaaaggtgg gaacaataca ggtctttata gagttggcaa
    38161 tatcaatcct agtggaaatg gtgcaggcgg acaagtgtat agtagcgaag gcttttctcc
    38221 cacacttaca actggaaaag gtgaaagccc aaagatatta attaaagaga atactaaaaa
    38281 aggatacatc aaagcatcta taggagatgg gataagacta gatcatatag aaggtaaaac
    38341 tggccgtgga agagttcagc acaaaaaaag ttgtactttg actactgcaa gtaatgctgg
    38401 cgtaattggt aaaaaattta gagtaaggag gttgactcca aaagaatgtt ttaggttaca
    38461 aggatttcca gacgattatt acgatagagc ggcaagtgtc tgttcagaaa ctcaactata
    38521 caagcaagca ggcaatagtg ttactgtaga tgttgttgaa gaaatagcaa agaaattaaa
    38581 atagaatatt aatacaatgc aaaatgtggt aggtttttcc ttccgcattt tgcattgcat
    38641 tagctttttt ggaataactt acctgtacta tcttaaataa aaaaatgcta ctatattata
    38701 aacatttaca aggagtgcat aatgttaata caaagcttaa aacgtggcga attaattgta
    38761 atgaaaatct tttagaaaag aaattcaaga atatcaaaga aagaaattat tcgcatttgc
    38821 aatgaaaaac acaattggcg gaaatctgcg acaaaaactc tacttaaaag acttgttaaa
    38881 aaaagagttc tacttaagag aattaaaatt ttccacatat attacatacc tatagttaca
    38941 gaaaaagaat atttcaaata taaaataaat gatttagagc cagattattt agatgaatat
    39001 tttatacgat taatgtccac tgtacataaa tttaaaaatc tagatgaaga agattaaata
    39061 tctcccttca tctactcttc acatatttta atagactttc aagcaataat tgacttaaca
    39121 aatcatgctt atcataatgt ttattctcat ctgcaaattt attaaacatt tcccacactg
    39181 tattatttat tctaactgta gttcttttta tagattgatc tggaagatct atagatatat
    39241 cattttcttt aatgacacat atatgataac tatcatcttt agttttaaac cattccagca
    39301 cattctttat attatcaatt tcactagata aatatttaat atcgtcatca atcttactgc
    39361 taatgctatc tatatgatat ttatcatcat aacttttatt atcttctaca aacttgtttc
    39421 cagttctttt atatcctttc ttattaagcc acttccttat agtactttca tttgccccta
    39481 attcatctcc aactttttta agactttcaa attcacttaa tttattatta atacaatcaa
    39541 caacttcatt aatatttttt tctttcaaat cactccaagt catataaatc ctcctcaaaa
    39601 aaataataga ttacaaatat catatatttg taatctatta tacatactat aaactaaatc
    39661 cttttttatt tcatcatttt tttgtatcct tttgcatttg caaaaacatg tttatctaca
    39721 tcactcataa ctattatgcc aggtatattc tttttaaatg cttcacctaa caatttagcg
    39781 cctccaccca taacaacaac cgcagctgta ctaactggat aatttaattt caattcattg
    39841 tatatttctt taaatagaga aatagatgca tctatatttt tctttatatc ttgtttttca
    39901 ccatttaggt aaaatccttt atttatgtag tcttgtattt tttctctttt tatctcaact
    39961 ttacctaaaa atctttcgtc catctcaaga gatttcttta ttgcatcata tatatttatt
    40021 gttcccacat ttatagaata tggatcagtc gctttattcc cttgtacaag cgcaatatct
    40081 gttgtctttc caccaatatc aactaaaaca acatctcttc ctgcaatttg gtcaactatg
    40141 tcttttgcat aatataagta tcctgtaaca ccttctggaa atgtttgaat agatcttatt
    40201 gttatatctc ttttagtagt ctcatttcct cttgtaaact caacatgata ttcttttcct
    40261 tgtaattttt caataagatt ttttcttaat ccggcaaatt gtttcactgg cagacctagc
    40321 cctagatcaa caatttcatc atctgtattt ctacatatag cccctaatag tagtggtaag
    40381 aagttttctt tctcatattt aactatattt atttcctcgt caccttcacc taggtaatat
    40441 gttttattgc ctattttaat gctatctgaa tctgaaccaa agttttttac ctctgtaact
    40501 ttactttcaa aaatatcatc tgtacttgtt ttaactgcat aatttccaat atctatacct
    40561 aatttactca tttatgttat ttccccctta ttattctaaa cttccaaaat caaaattgtt
    40621 agctggatct tctatttctt ttttctgttc aactacagca ttatcctttt tttcttgcat
    40681 tttttcccaa acaagctctt ttaagtaagc tgtagctgat aatttctcat ctaaaaactt
    40741 ttcaattgct ttttctttat cattgttttt aaatgttaga actatcctac tcattcaacc
    40801 acttcctttt ttataaaata ttataaaatt tattaatatt tatatatatt ttactaaatt
    40861 ttacacagta attcaataga tttataagat attttttata atattttata attttttacg
    40921 taattttata attttttata aaatttatca ttttgtatat aattaaaaac acacttttta
    40981 taattttgca taaaaaaaga gtgtttcata tatttctaaa cactcttttc tactttttat
    41041 aattatctaa ttgtaaaaga agcttcagct ggactagaga ataatataat acctcctgta
    41101 cacacacctt ttcctttaaa tttagcaata tatgaaccct tttttagccc tttaaaagtt
    41161 actacaccag ttttagtagt tccagctaat ctaaagccta catactgaga tgatacaatt
    41221 ttgccagcct tatatacatc tatatttcct tcaaatccta aaatatttcc aagcgtagat
    41281 gttactctcc aagataactg cccaccactc attgcagtta aattagcagt accacctgga
    41341 acaacaacag atttagtcga aggcgaatct gagtttggtt ggccaattaa ttcaactgtt
    41401 tgtgaatttc cagtaccttc ataatcattt ccatcagcaa aagctgtaaa tggaatcatt
    41461 actgcgcaaa gcgttagtaa taaagcaatt gtttttttca tttgttttcc ccctattttt
    41521 ttatattatt ctcaattaca gtttcctttc tttacgtgcc ttaataatca tattgtaatt
    41581 atgctcagca gtttcaaatg ctcctaccaa aggagttata attacacttt ctattaagca
    41641 caattcatca tagtttaaac tagcttctcc agcatagaaa ttatttaact tatctaaatc
    41701 tattctagtt aaaacggaaa ctgattccat tgagaatttg taaacatcaa taagtttata
    41761 taatccacct atatagtttt ttgctacttc atggctctta aaaaattcat cttttcctgt
    41821 atgtaggttt acttccataa ttccctccat tgttcttata tttttaacct tcaaataata
    41881 tttacttctt cttcaaaaca gaatattcta tcacggtaga atattctgtt tttttcattc
    41941 tatcatgata gaataatatt ttcaatcatt ttttctattc tattttattt aaatagaata
    42001 gaaaaaaaga acacttaata tttttcaagc taatatatta agtgttcttt ttatattttt
    42061 acaagattat ataaaattat tctttaatca attaaagtgt ttttctattt cttaataata
    42121 agaaatgata taaaattgta tcattttaaa gattttgtga tataataaaa gcaagaagaa
    42181 ctacaatcta tttaggcgta gagtggagtt cataataaac gtagtttatt ttttgaattt
    42241 aaatataaat ttaaattcaa cctgtaagtc actctttgca cgagagtggc tttttgcttt
    42301 tttgaatagt tcactgatta agtaaactac cacactagct gttaaactag ctaaaacatt
    42361 aaacaaaaag ttatccatgt aactcacctc ccctcgaatc gttgggagga taatcttttg
    42421 tacatgaact ccactctata gattgtatat tacgctcttc ttgctaaatt taattatacc
    42481 atattttgta atatcagtta agagtttgca ctacaataat cagaaagctt gttccactca
    42541 caatcaaccc ctattatttt aagaatatca ttgacttggc tatttaaatc tttaatatct
    42601 gatttagaca ttaaaggatc tttcattatt tcatttagaa aaatactatc aatgattaaa
    42661 catacatttt ctgataaata ttcacgtttt actgagatta ctgttccaac tgtactttct
    42721 tttagtgtct tatatgctac actcaatatg catggttcta aattaattcc ttctagtact
    42781 gtttcaaagt aatattttat tcttatattt tcatttccaa taaatatttc ttcattgctg
    42841 cttatcttct ttaattttct cattatgcct aacatcttag cattcacttc atagtttatt
    42901 ccacatctct ttgatgctaa actcgacatc aagtctcttt ctgaataaat tacccattga
    42961 ccattatagg aaaatgatgt tttagcgata tccatttctc cttttccagt aatattaaat
    43021 ttaggctcta gtttatttat taagtaaatc tcataaaaat ccatagtata tttattatct
    43081 aattctatat actcaaatct taaattctta ttacaccaat tttctttttt attacttaaa
    43141 tgactagcgt gtctatcgca gatattctct gttttcccaa cgtataaaca ttcttccgta
    43201 tctagattaa tatatttata aacataatac attttttatt ttctccaatt attatttata
    43261 gtaatatcct tcttcattta ctagaccttg atcaaataaa tttctcctaa cagtttcaag
    43321 tctgacagga tctttgctat aatcaacttc tctttcttct tttttaacat cttcatcatc
    43381 ccaatactta tccaattctt ctttaaactt taaatcatct ttttgatgaa ttataacttc
    43441 acttatttta tttgaaagtg ttgatttaaa aaaatcataa ttctttgtat ttataatatc
    43501 agtattatct ctttcaaatg ctatagcaat agacttatta aaagcattca gataaacatc
    43561 tttcttaaaa tcaaactctt taaaatcttc tttaaatagt ttaatcgtcc ctgttgtaaa
    43621 aatattttca tttggtatat aaaaactaaa agacacttca ttgtcctgct tctttttagg
    43681 tatataatct tcaaccaata tatctttatc aaaatatttt ctaggttcat aatctatcac
    43741 agaaaaaatt atttcatcta tttttctatt ttttcttttt tcttctttta ttgaaacaac
    43801 catgttgcct tttttattta tttcattcat tgctcttttt agaacatttt gtttaaaata
    43861 tttatactct ggatatacat tatcttttaa tttcaaataa aatcttaatt catctaactt
    43921 atattttatc tccacttcct tattttctct gctccatagt ctaaataaag tgtataacct
    43981 ctgagtatat gcacctctaa aattaaataa cactgataaa ttaatagctg tatatccatt
    44041 tttctttttc tgcattttta caaaatcagt tatatgattg tatagaactt catgcatcat
    44101 aattgtataa atttggtctg tatgatccaa ttcatatgta ttaattaaac cacttccaaa
    44161 agtttttaac ttgccagttg tctcttctat atagtcaaat tccaaaacac tttgttgaaa
    44221 catgttcaaa atttctttta tatttttatg ctcataatca ttattgtttt tcataaatac
    44281 ttttagttct tcttttgata tagttgtaac ataagatgaa ttttgctgtt tctgagcatt
    44341 aaaaagtatt ttgtaaaata atttattttc cacatttgta aaatcatatt tactttttat
    44401 taaattattt ggttgcatta aaatttcttt tttttccaaa atctatcacc tcatataaat
    44461 tataatacct aatttataaa aaggtcaacc atttttgaaa gacgctcacc tttgaccctt
    44521 aaaatgatga cctttgaccc ttaaaatgat gacctttgac ccttaaaatg atgacctttc
    44581 gacccttaaa atgatgacct ttgaccctta aaatgatgac ctttgaccct taaaatgatg
    44641 acctttcatc tctgaaacct agatatacca attattatag cttgtctaaa aactattaaa
    44701 gactttaaaa actgttttaa aaactattaa agactagaaa agatgttctg aactattctt
    44761 tttttatatt aaaaaacttt agtatttatt tttctagtat actttaaaca cttactaaaa
    44821 ataatttctt ataaaagatt ggagatgaag aattttttat gcttgaaaac agaaaacaaa
    44881 ttcagaaaga aatttactta ccaatagcaa catattgttt aaaagataag caatattata
    44941 taaaagaata tggagcacta ttaataaaga gtgctgaaaa tagtgacatt tttaataccc
    45001 ataaaaatag aattttgtat aagaataaac ttgatattca agaaatagca aatgaactga
    45061 atgtaaataa agcaacaatc caaagaaata taaaaaaact agagaagtta gattttaaaa
    45121 ttctaaaaat agaaaatacc ctaaatggaa ttgtatattg tttaccatca gaaaataata
    45181 ttgatttaaa caaatttgca ttgataaatt atgaaatgct taaaaaaatg gtcaataaat
    45241 ttaaatcaaa tacaataaaa gtatattttt tacttaaaac aatcactaca gaaactaatt
    45301 ttaaacctgc aactaatagt tttatagcag aaaatatagg actaagttct aaaagtaaaa
    45361 ataatttaga tatcataact tcttctgtta aaactttaga agaaaataaa tacattgaaa
    45421 caaaaaaagt aaatgtatat gaatatgaca aagaaaaact tagagaagtt ccaaaaataa
    45481 gaaaagttta tcggatttgt aattttgatg agtggaaaaa ggaaattgat aaaaataaag
    45541 tttattaaat atagcttaaa agcatttaaa ggcttgtctg acgtgtttta attacaaact
    45601 tgatgttatt tacctaaaaa gatacaaatt tgcttaaaaa tggaaataga aggtcaaata
    45661 tataaataga gaaccaaata aaattatatt ggctctctat ttatcttctt cccaatcctc
    45721 aataaacttt tctaaacttt ttaatttatt ttcagacact tcttcatcat catgcagagc
    45781 acttataaaa ctttcaaaag aatttttgtg aaagaaacta aagaaacttt tagtctcaac
    45841 ttttaaatat tcttcttttt ctattaatgc tttataatat gtaaatctat ctttcttaac
    45901 aacctctaaa aatcctctac caactaatct cctcaagaaa gttaacatag ttgatttttt
    45961 ccattcgtac ttttcgccta gtgtcttcaa aatttcagta gatgcaactt ctttatcttc
    46021 gctgtcccaa ataaacatca taaccaacaa ttcactttct ggaatctttt ttatcttcat
    46081 aaagtacacc accttctaaa agtatatcta aaatactata acaatagagt taactacaca
    46141 atactaaatg tctaaaaatg ttttaccaat ttttaccaat taatttttct tt
//
LOCUS       DAMJWC010000026        46146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMJWC010000026 DAMJWC010000000
VERSION     DAMJWC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.026"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            179..3727
                     /locus_tag="PC503_001696"
     CDS             179..3727
                     /locus_tag="PC503_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2527670.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3912..5846
                     /locus_tag="PC503_001697"
     CDS             3912..5846
                     /locus_tag="PC503_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF2527671.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5952..6947
                     /locus_tag="PC503_001698"
     CDS             5952..6947
                     /locus_tag="PC503_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2527672.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6919..7704
                     /locus_tag="PC503_001699"
     CDS             6919..7704
                     /locus_tag="PC503_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2527673.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7692..8390
                     /locus_tag="PC503_001700"
     CDS             7692..8390
                     /locus_tag="PC503_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527674.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8513..8986
                     /gene="ybaK"
                     /locus_tag="PC503_001701"
     CDS             8513..8986
                     /gene="ybaK"
                     /locus_tag="PC503_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF2527675.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKFYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9183..10022
                     /locus_tag="PC503_001702"
     CDS             9183..10022
                     /locus_tag="PC503_001702"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF2527676.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKN
                     VVI"
     gene            10035..10583
                     /locus_tag="PC503_001703"
     CDS             10035..10583
                     /locus_tag="PC503_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF2527677.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10649..11830
                     /locus_tag="PC503_001704"
     CDS             10649..11830
                     /locus_tag="PC503_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF2527678.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEIKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12125..12511
                     /locus_tag="PC503_001705"
     CDS             12125..12511
                     /locus_tag="PC503_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527679.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12661..12924
                     /locus_tag="PC503_001706"
     CDS             12661..12924
                     /locus_tag="PC503_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2527680.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13053..13895)
                     /locus_tag="PC503_001707"
     CDS             complement(13053..13895)
                     /locus_tag="PC503_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2527681.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14190..14924
                     /locus_tag="PC503_001708"
     CDS             14190..14924
                     /locus_tag="PC503_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2527682.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14934..16067
                     /gene="nagA"
                     /locus_tag="PC503_001709"
     CDS             14934..16067
                     /gene="nagA"
                     /locus_tag="PC503_001709"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2527683.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16166..16915
                     /gene="nagB"
                     /locus_tag="PC503_001710"
     CDS             16166..16915
                     /gene="nagB"
                     /locus_tag="PC503_001710"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2527684.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17090..17362
                     /locus_tag="PC503_001711"
     CDS             17090..17362
                     /locus_tag="PC503_001711"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527685.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18022..18726
                     /locus_tag="PC503_001712"
     CDS             18022..18726
                     /locus_tag="PC503_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527686.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18728..20215
                     /locus_tag="PC503_001713"
     CDS             18728..20215
                     /locus_tag="PC503_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527687.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20420..22033
                     /locus_tag="PC503_001714"
     CDS             20420..22033
                     /locus_tag="PC503_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2527688.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22396..23226)
                     /locus_tag="PC503_001715"
     CDS             complement(22396..23226)
                     /locus_tag="PC503_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2527689.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23299..25026
                     /locus_tag="PC503_001716"
     CDS             23299..25026
                     /locus_tag="PC503_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527690.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25063..26925
                     /locus_tag="PC503_001717"
     CDS             25063..26925
                     /locus_tag="PC503_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527691.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27258..27947
                     /locus_tag="PC503_001718"
     CDS             27258..27947
                     /locus_tag="PC503_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF2527692.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28052..28738
                     /locus_tag="PC503_001719"
     CDS             28052..28738
                     /locus_tag="PC503_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF2527693.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28755..30662
                     /locus_tag="PC503_001720"
     CDS             28755..30662
                     /locus_tag="PC503_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF2527694.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31115..31804
                     /locus_tag="PC503_001721"
     CDS             31115..31804
                     /locus_tag="PC503_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527695.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32240..32779
                     /locus_tag="PC503_001722"
     CDS             32240..32779
                     /locus_tag="PC503_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527696.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            32798..33841
                     /locus_tag="PC503_001723"
     CDS             32798..33841
                     /locus_tag="PC503_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527697.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            33843..34679
                     /locus_tag="PC503_001724"
     CDS             33843..34679
                     /locus_tag="PC503_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527698.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            34784..35458
                     /locus_tag="PC503_001725"
     CDS             34784..35458
                     /locus_tag="PC503_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527699.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35458..36510
                     /locus_tag="PC503_001726"
     CDS             35458..36510
                     /locus_tag="PC503_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2527700.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            36740..37588
                     /locus_tag="PC503_001727"
     CDS             36740..37588
                     /locus_tag="PC503_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2527701.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37578..39242
                     /locus_tag="PC503_001728"
     CDS             37578..39242
                     /locus_tag="PC503_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2527702.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39291..40547
                     /locus_tag="PC503_001729"
     CDS             39291..40547
                     /locus_tag="PC503_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2527703.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40570..42651
                     /locus_tag="PC503_001730"
     CDS             40570..42651
                     /locus_tag="PC503_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF2527704.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIIVMIL
                     SMLYIKKYKRR"
     gene            42688..43773
                     /locus_tag="PC503_001731"
     CDS             42688..43773
                     /locus_tag="PC503_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2527705.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            43827..44951
                     /gene="wecB"
                     /locus_tag="PC503_001732"
     CDS             43827..44951
                     /gene="wecB"
                     /locus_tag="PC503_001732"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF2527706.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            45029..46003
                     /locus_tag="PC503_001733"
     CDS             45029..46003
                     /locus_tag="PC503_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2527707.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        18404 a         4678 c         8002 g        15062 t
ORIGIN      
        1 gaatgatgaa atatgaataa agattttaca aataaatctt aagctatctt atttaattct
       61 aatacaggaa gaaggtaaat gtatattgaa aaaatcatag aaatagaagt aaacaattta
      121 aataaataca aaggtttgca aaagaagtaa tataattata tacaatgagg atgtgagtat
      181 gatgaacaga ctaaagccaa gaattttagg tattagtatc ttgtttatta ttataattat
      241 tttaacatgt ggagctgttt tcaagtttaa atttaaatta gataataaat taaaagaaac
      301 cacacataca tatttgtctg agtttacaga acacaatata attaatctca agacaagact
      361 tagtggtcaa tttgacatgc ttgaatctat tgctaacttc ataggaaact tgaataatat
      421 aaatgatgaa atggtgattg atttaatgga ttctgatgta aagcgaagtt ctttaattag
      481 aatgactatc tctacattag atggggaatg ttattctaat gatggaatta cccataatgt
      541 tcaagataga gattatttta aaaaagctaa aaatggagaa aagaatatat cagagccttt
      601 aaaatctatt gttaataata aagaaataat agttttatct accccagttt ataaaagtgg
      661 gaaaatagtt ggtgttttaa gtggaattta tgattcaaaa aagttaaatg agttattagg
      721 attatctgca tttgatgaaa aagcagatgt ttttgttgca aagaaaaatg gagatatagt
      781 tgctcaaaaa acaaataaaa atagaaagac gctatcatgt atatttcagc tttttgacaa
      841 agataattgt gatgaagatg attgtctaaa aactataaaa gaaaatatga aaaatgataa
      901 gtctggatat tttaattata acttagataa tgaaaaattt atgttaaact atcagccact
      961 tggagttaat gattggtatg ttttttctgt tgtgccaaat aaaatagtat ctattcagtc
     1021 agagaatata tcttatgatg tatatatttt tgcattagaa atactactag ttatattgat
     1081 ttttataata tatatagcat gtattataaa taataacacc aaaattatta taaatgaaaa
     1141 agaaaaattt aaagtactca ctgataatat attaggaggg gttaaaacct gtttaaaaga
     1201 tgaatatatg actatgacat atgtaagtca ggggttttta gagcttacag gttactcttg
     1261 tgaagattta aataaaatat ttaaaaatag atttaaagac atgatttata aagatgattt
     1321 agacaagttt aattgtatta ttctaaatca attagaaaaa caagataaaa ttgaagttga
     1381 atatagaatt gtaagaaaag atggaagtat aatttggatt ttggagagaa gtaagtctat
     1441 aaatgataat aaaggaagtg agtgtattca gggagtttta actgatataa cagaacttaa
     1501 gaaaatacaa gaagaattag attcaaaaag atttgaaata caggctatca atgatagtat
     1561 tgttggtgga atagtgataa ctgagataaa tgatgatttt gatagtatat atttaaatga
     1621 aggttattta aatatgattg gatatacacg caaacaactg gaagatgagc taaataataa
     1681 attaatcaaa cttattttta aagatgatag aacagaatta attaatagta taaacaaaca
     1741 actcaaatta agtgatacat ttgcatctga acaaagagtt gaaaaaaggg atggcactat
     1801 tatatggatt ttattaaaag gaagaaagat gatttatgat aatggaaaat ctgtactttg
     1861 ttgtgttatt gtagatatta cttctgctaa attattagag caagaactta aaaagagtga
     1921 agaacgtcat gaaatcattc taaagcagac gcaaaatatt ataatagaat gggatataga
     1981 aaaagataaa atgaatatat cacctaattg gtataataag tttaaatatg accctataac
     2041 tgaaaacgca acaaaaaata taattaaatc agtagatata tatcatgatg atatggataa
     2101 gtttatttca ttaattaaac ttacttcaca aggtagtgag tatgaagagt gtgaaattag
     2161 acttagaact agagatacta tttacgcttg gtttagtata aaggcaacaa ctttatttga
     2221 taataatggt aaaccttata aagtagtagg aagtttgact gatattgatg aatcaaaacg
     2281 agaagctgaa aagttgaaag aaagggcaga aaaagaccct cttacagatc tgtataataa
     2341 aaaagcatca caatcactta tagaggagta cataacattg gataaaaaaa gaaaaggtgc
     2401 tttaatgatt attgatattg atgactttaa aggaataaat gataatttag gacatttata
     2461 tggggatgct gtattaagtg aaattgcaaa tgacctaata aatctattta gagcaaccga
     2521 tatagtaggc agaattggtg gagatgagtt tattgtattt ataaaagata tttctgaaac
     2581 aagagatatt ataaataaag cagaagaatt ggtaaaaaca tttgaaaggt cttttttagg
     2641 taaaggacga aattataaaa tatcattaag tgtaggaatt gctaagtttc cacaagatgg
     2701 tatggactat atgacactat ttagaaatgc ggatatagct ctttactcag ccaaagggaa
     2761 gggcaagaat tgttatacat tgtatgataa aaaatttgat aaagtccaat atataactaa
     2821 tacaagaaat gcaggagata gtgataatgt agagatgtct tttaaagaac atatcacaaa
     2881 ttatatattt gatatactat atgaatcaag tgatatagaa gtggcagtaa atttaattct
     2941 aagtattgta ggtaaacact ttaatgtgag tcgcatgtat atatttgaaa attcagatga
     3001 taatcgagta tgtaaaaata catttgaatg gtgtaacgaa ggtgtaacct cggaaattaa
     3061 taatcttaaa aatatttgtt acaaggattt aggcaactat cttttaaatt ttaatgcaga
     3121 tgggttattt tattgtaatg atattgaaaa tttaggtagt gatgtgaaaa aagtacttaa
     3181 gccacaaggc atacgttcaa tattacaatg taaaatttta gagggtaatg aatttagagg
     3241 gttcatagga tttgatgaat gttcatataa tcgtatgtgg actaatgatg aagtgaacac
     3301 tttgacattt atatctaaaa cgctcagtat gtttttatta aaaatgcgta ttcagagtaa
     3361 gctagaagag tctttaacaa ttcaaaaatc tgtgatggat aatatggata tatgggcata
     3421 tgttgttgac aggaatacct atgaattact atttatcaat aaaaaaatgc ttgagtcagc
     3481 accaaacact catgtaggtg atttatgtta taaagcgata tggaataatc aagataaacc
     3541 ttgtaaaaaa tgccctatga tatatttaaa agatggtgat gatacttata aatcattcat
     3601 gcataataaa aagtttgagg tacaggcaaa tataactaca actactttga aatggtttga
     3661 tggtaaagat gcatgtttaa tatttggaag tgaaataact agtattgaag ctgaagaaaa
     3721 tacttaaaat actgtgttat atatatactt aaaatcgcaa tttgaattta ttagacttaa
     3781 aatgtctata taaatcattt aagttgtggt tttaagtatt ttttatgata taattaagcg
     3841 ttaagaacaa aattaaaaga tacttttgta taaaaaaata tttgttaaat atatattgag
     3901 caggtgataa tatggaaaat aagtttttac caataagcaa acaagatatg atagatagag
     3961 gatgggaaga attagatttt gttctagtta caggagatgc ttatgtggac catcatagtt
     4021 ttggaacagc aataatatct agagttttag aaagtgctgg gtataaagtt ggaataatag
     4081 ctcaaccaga ctggagaact acagatgatt ttatgaagct aggaaaacct agacttgcat
     4141 ttctagttaa tgcaggaaat atggattcaa tggtcaatca ttattctgta agtaaaaagc
     4201 atagagaaaa ggatatgtat tctccaggtg ggaaaatggg ttatagacca gatagagcta
     4261 ctatagtata ttgcaataaa ataagagaag catacagtga tgttgcaata gtaataggtg
     4321 gaattgaagc gagcttaaga agatttgcac actatgatta ttggagtgat aaggttagaa
     4381 agtctatgtt aatagatagt ggagcagatt tattagttta tggtatgagt gaaaagcaga
     4441 ttgtagaagt agccaatgca cttaatgatg gatatgaccc aaaatacatt agacatattg
     4501 atgggacatg ctatatttca gatacattgg aagaaatata tgataaatat atattaattc
     4561 catcatataa agaaatttgt gaagataaaa tgaagtatgt agaagctttt aaaattcaat
     4621 atgatgagca agacccattt agaggtaata taattgttca acctcatgga agtaagtatc
     4681 tggttcaaaa taagccagaa aaaccactta gtagagaaga attagatgaa gtatatggat
     4741 taccatatca gaagacatac catcctgtat atgaaaaatt tggaggaata ccagctatag
     4801 aagaagtaaa atttagtata gtaagttcaa gaggctgttt tggtagttgt tcattttgtg
     4861 caataacatt tcatcaaggt agagcagtgc aaagtagaag tgaaaaatca attattgatg
     4921 aagcaatagg aataacaaat ttagatgatt ttaaagggta tatacatgat gttggaggtc
     4981 caacagctaa ttttagaaga ccagcatgta aaaaacaaat tactaaaggt gcttgtaaaa
     5041 atagacaatg cttatctcca tcaccatgta aaaatttaga tgcagaccac agtgaatact
     5101 tacatttact tagagctgta agaaaattac ctaaaataaa aaaggtgttt gtgcgttctg
     5161 gaattagata cgattatgta atggcagata agaacaataa atttcttaga gagttgatag
     5221 agcatcatgt aagtggtcag ttaaaggtag ccccagaaca tatatcagaa gaagttttaa
     5281 agtatatgca aaaaccagca ggaaaaactt atgataaatt tagacagaag ttttttgcta
     5341 taaatgaaga attaggtaaa aagcaatatt tgatacccta tttaatgtct agtcaccctg
     5401 gttctacctt aaatagcgct atagagttag cagagtattt aagagatact cactaccaac
     5461 cagagcaggt tcaggatttt tatccaactc cagggactct atctacaacc atgttttata
     5521 caggtattga cccgcttaca atgaagccag tttatgttcc taaatcaaaa cgtgacaagg
     5581 caatgcaaag ggctttatta caatatagag cacctagaaa ttatgatttg gtatactctg
     5641 cgttagttga agcaggaaga gaagacttaa ttggttttgg acatagatgt cttataaagc
     5701 caaaaaatga aaagccttat tttaatagaa ataattctaa aaaaaatgta tctaaaggaa
     5761 caaataaaaa caaaaaaact aatacaaata acagaagtaa taaaaatcaa caaaaaagtt
     5821 caactaaaaa aaagaaaaaa cattaaagta taaataaaaa tacttaaaaa agaaggatta
     5881 ttcgataaat taacagaaat tagtataaat aaatataatt attttaatga cgttaccttt
     5941 gggaggaaga gatgaaaaag tatatttcta taatattatt agtggtgttg actatggttg
     6001 ttttggtagg atgttcacca ggaaaagata accctaaaaa taaggagcta tcagttgtca
     6061 aacaagtaaa agtagctgtt ccagatggac taccagcagt ggcaatagct aaacttgcaa
     6121 atgaaaatcc agagattaaa gaaggatatg aaacagtgta tagcattgaa aagacacctg
     6181 aagcgatttc cactagagtg atgaaaaaag atgcagatat agctatagtt ccttcaaaca
     6241 tggctgcaat agcgtataat aaaacttcat catataatat tgttggaact gtaggaatgg
     6301 gttcacttta tttggtgtca acagaaaata taaaagatta ctctgattta gttggtaaag
     6361 aagttggatg tactggaaaa ggacttactc cagacataac tataaaaagt cttttgttac
     6421 aaaaggatat aaattattca gatataaaat ttaattatgt aaattcagca agtgaactgg
     6481 taccattatt ggctactggt aaagttaaaa caggtattgt tccagaacct gcacttagtg
     6541 ctttgatgtc taaaaatcca gacataaaaa ttataaaaag tttaaatgac tcatggaagg
     6601 aagtaagtgg ttcaaaagat ggttatcctc aatctacttt aattgtaaag tctgaatttt
     6661 taagagataa taaagatttt gttgattctt ttgtaggtca attatcaaat agtatagatt
     6721 gggcaaacaa aaatcctgaa gaattaggtg catattctga aaaaataaaa atatctactg
     6781 aatcaaagat aataggaaaa tctcttgaaa gagctaattt gaaatatatt ccagttaagg
     6841 acatgattaa agattataaa aattactatg agaaattagc taattttgat gataagacat
     6901 taggaggcaa agtaccagat gaagcaatat actttgttga gaaataaaaa aaataaagaa
     6961 caatttatag ataaaatgga ggtaacactt tcttgtgtta tcctcttatt tttatggcaa
     7021 attattgctt taaaaattga taatgatatt tttttaccaa cagtaggtca agtgtttaat
     7081 agtataaaag agattatgct aaattctagt ttctatatag atatacttta ctctatgggg
     7141 agatgttttt ttagtttttt actggctatg atttttgcta ttatactttc aatagtgtct
     7201 tatttaaata gattttttag aaacttatta aagccaatca atgctttgac acgttcaata
     7261 ccaactatga tattggtagt acttgcactt atttggtttg aaaaggatag tacccctttt
     7321 atagttggat ttactatagt ttttcctata ttgtatgata acgttttggg cgctatattg
     7381 aatatagaca agaacttatt agaaatggct aatgtgtata aaataaggtt tatagataag
     7441 gtgttaaaaa tttatttacc agccataaaa tttcaaatta tatctatact agtatcaaca
     7501 ttttctttaa gtttgaaagt tgctatagca ggagaggtgt atagtcaacc tacatatggt
     7561 attggaacta tgatacagac tgaaaaaatt aactttaaca catctggaat atttgcatgg
     7621 ataattattg ttcttttaat atctgctatt ttacaaatag ctcaaaagtt tttagcaagg
     7681 agagcttttt tatggaaaag ataaagttga gtattgaaaa tataaataaa agatatgata
     7741 gtcgtattat atttagagat tttaatattg atttttatgt aaatgaggta aattgtatcc
     7801 ttggaaaatc tggttgtgga aaaactacac tcttgaacat aataagtggg attattaaaa
     7861 atgacaccaa caatctaaat atcaaagaaa atttaaatag agtaggaaat aagcttgaag
     7921 ctagttacat atttcaagat gatagactta tagactggtt aacagtagaa gaaaatataa
     7981 agatagttgt aaataaatac tataataaaa ctcaattaaa taaaatttgt gatgaatact
     8041 tggaattggt tggaattagt gattataaaa aattctatcc tcaaatgctt agtggaggta
     8101 ttagacaaag agtaaatatt gctagagctt ttatatatcc atcaaaaaac attataatgg
     8161 atgaaccttt taaatctatt gatgcaaaga atacacagct tataatggat aattttagaa
     8221 atatattaag aaaagaaaag agaactgtgt tatttgtaac tcataatatt gaggaagcat
     8281 tgtttttagc agataggata tttattttag gagactctcc aattagaata aaaaaaatat
     8341 taaaaaattc taaggaattg gaaaaaaatg aagttttgaa gttgatatag agttataata
     8401 atactgtcgt tttaaaatat atttggttaa aatctataag actatattaa aatagtacag
     8461 aatattcaaa actgtgtata atgttcgtat tttataaaaa ggaagtgaat gtatggttaa
     8521 gactaatgct atgagaatat tagattcaaa taagattgat tataaagtaa tgtcttatga
     8581 agtgaaaagt gaacatgtgg atggtgttga ggtggcacat gatataggaa gagatgtaaa
     8641 tgaagtgtat aagacattag taactcaagg agttagtaag aatatatatg tatatgtaat
     8701 accagtacat gaaaacttag acttaaaaaa ggctgcaaaa gtagctaaag agaaaagtgt
     8761 agagatgatt catgtaaaag atataaataa gcttacaggt tatattagag gcggatgttc
     8821 tcctataggt atgaaaaagt tttataaaac ttttgtaaat gaaagtgcaa agaatttaga
     8881 tacaattatt gtgagtgcag gaaaaatagg atatcaaata gaactatctc catttgattt
     8941 acaaagactt ataaaagtag aatttgtaga tgtaataaaa aaataagaat tacatataaa
     9001 atatagagct tatattctca ataataggtg ttgtaatatt aataaaatga ataagaattt
     9061 taaaataaat attcagttac ttatgtgtaa ttggtataaa aatattgaga aattttaaaa
     9121 acaatggtaa agtgtaagta taatcacgaa tattttttat aaagtaatgg agggatgttc
     9181 gcttgagaaa aataaaatct gaacaaatcg tcgagcaggt aaaaaaactt tgtatagaag
     9241 cgagcctata tttaggagaa gatgttttaa gttgtataaa agaaaaagcg aaaagcgaaa
     9301 agagtgaagt tggaaaaaat atattgaata tattagttga aaatgctgaa atagctaaag
     9361 aaaaaaatat accaatatgc caagatactg gtatggctgt attttttgtt gaaataggac
     9421 aagaagtttt aattgaagga gacacactta ctgatgctat aaatgaggga gtaagacaag
     9481 ggtatgaaga aggctactta agaaaatctg ttgtaagtcc aattaacaga gtaaatacaa
     9541 aagataatac acctgctgtt attcattatg atatggtaaa aggtgataaa attaaaatag
     9601 aatttgcagc taagggattt ggaagcgaaa atatgagtaa gatgaaaatg ttaaagccat
     9661 cagatggatt ggaaggaatt aaaaaattca taatagatac agtttcagaa gctggaccta
     9721 acccatgccc tcctatggta attggagttg gtataggtgg gactgtggac aaatgtgctc
     9781 aaatagctaa aaaggcactt tttagagaac taggtgaatt taataaggac gaaaatatag
     9841 caaaacttga aagtgaacta ttaacagcta ttaataaact tggtatagga cctcaaggct
     9901 taggtggtac tacaacagct ttgggattaa acatagagac ttttcctaca cacatagcag
     9961 gtctacctgt tgttgtaaat ataaactgcc atgcatcaag acataagaat gtagtaattt
    10021 aggaggaaaa taaaatgata aaaataacta cacctgtaaa tgaaattgat atagcaaaat
    10081 taaattgtgg agatacaatt agtttgagtg gtatacttta tacagcaaga gatgctgctc
    10141 ataaaagatt gatagattgt ataaataaag gtgaagaatt accatttgac gtatatggtc
    10201 aaggaatata ttatgtagga cctactccta caaagccagg agaagttata ggtgctgcag
    10261 gtccaacgac gagttataga atggatgatt tgactatacc tcttttagaa agaggtctta
    10321 gattgatgat aggcaaggga aaaagaagtg atgaagttat agaaggtatg caaaaatacg
    10381 gagcagttta tcttgctgca ataggaggag ctggagcgta tatttcaaat tcaataaaat
    10441 catgtgaaat tattgcatat gaagatttag gagctgaagc tataagaaag attgtagtag
    10501 aagaccttaa gcttacagta gcaatagata gctatggaaa taatatatat gagcaaggtc
    10561 gagcaattta tgaatgtaaa taatgtttag aaataaatat gaatatcaaa attaaaaata
    10621 gttgtgtata ttttaaggag gaaaattgat gtctaaggat tatgcaaaat tggcattaga
    10681 aatgcatgaa atcaacaaag ggaaagtaag tgtagaaagc aaggtagaaa ttaaaactaa
    10741 ggatgattta tcaacagcat atacaccagg ggttgctgaa ccttgtttaa aaatacatga
    10801 aaatcaagat gatgtttata gatacacttc taaagggaat ctagtagcag tagttagtga
    10861 tggaagtgct gtacttggat taggtaacat tggtgctgaa gcatctatac ctgttatgga
    10921 aggtaaagct atattattta aacaatttgc agatgtagac gcttttccaa tatgtttaaa
    10981 gactaatgat gtagatgaga tagttaaatc tgtagagttg atggagcctg tatttggagg
    11041 tataaatttg gaagacatat cttctccaag atgttttgag atagaagaga gattaaaaaa
    11101 atctttaagt atacctgttt ttcatgatga ccaacatggg acagcaataa tagttgcagc
    11161 cgccataata aactcaataa agttaattga aaataaaaaa atagaagatt tagaaatagt
    11221 tataaacgga gcaggagctg ctggtatagc catagcaaag atactactta atatgaatgt
    11281 taaaaatata atcttatgtg atagaagtgg agcattggaa gctagtatag aaaatctaaa
    11341 ctatgttcaa aaagaaatgt taaaagtaac aaatataaga aatgaaaaag gacctttaaa
    11401 agatattata aaaggaaaag atgtatttat tggtgtttca ggtccaggag ctgttacaaa
    11461 ggaaatggtt gaaagtatgt ctgagaagcc aataatattg gcaatggcaa atcctactcc
    11521 agagataatg ccagaagaag caaaattagg tggagcattt ataatgggaa caggtcgttc
    11581 agacttccct aatcaagtca ataatgtact ggcttttcct ggaatattta gaggtgcact
    11641 tgatgttaag gctaaagaga taaatgaaga aatgaagata gctgctgcat atgcaattgc
    11701 taatacaata agtgatgaag aaatatgccc agagtatata ttaccagatg tatttaataa
    11761 gaatgtagta aaaaatgttg ctaaggcagt taaagaagca gcgataaaaa ctaaagtaaa
    11821 tagaatataa atttttatat gttcatatat ccttatatta tcgggtatat gggcattttt
    11881 attataggtt tatactcata tatccttact tttatataca tatctttatg attaaaggtg
    11941 ttagaaaatg tagtaaattt tatactatca gactctatct ttattacttt agtagataca
    12001 tggttgtaaa ggtttataga aaaaaatata ggaaggcaga tttttattgt tgcgtatata
    12061 tgagaatgat ataatatgaa tattataaat taataaattt aaatttatgg aggtacaaga
    12121 gatgatggaa tataaagtta atgaccaaga acttaatgct tcaatgttta tcccattcgt
    12181 caacaggata tggccaggag attatgatat ggataaaaca cagactgcat tatcaaaaac
    12241 tttgaatata actgcttatg atgataaagt gcttgtagga tgtctgcgag ttctttcaga
    12301 tggttattat tttggaacaa ttacagaatt gcttgttctt ccagagtatc agaaacaagg
    12361 cattggtagt aagcttttcc agcttgctaa agagaacacc ccaactatgc tatattttgg
    12421 tgcacagcca ggagtagaag cgttctatga aaaaaatggg tgccaaagaa gtctgcaatc
    12481 ctacataata aaaaagaaag atagttatta aagttccagc tttcaataat cttaaaagta
    12541 caatatttta gtggaatcat ttcatttttt attactaata tgacataaac atgtcatatt
    12601 agtattgata tacttttaat atggttaaga gccaaagaaa aatataagga gtgatttaaa
    12661 atggaagaaa ctaaattttg ccaatgctgt gcaatgccaa tgggacaaac tgatgaatta
    12721 tatgggacaa ataaagatgg aagtaaaagt actgattatt gtagttattg ttttaaagat
    12781 ggtgagttta cagctgatat aagtatggaa gagatgatag aagtttgtat ccctcatatg
    12841 cttcaaagta ataaggatat gactgaagat gaagcaagaa caatgatgaa caatttcttt
    12901 ccaacattaa aacgctggaa ataattttat gcaaaattag ttatatgcaa aacatgaaat
    12961 atggtgttga gaataagggg tggtgtgctt tatagcatac cacctgtttt gttacttgga
    13021 gttcagttat tttcctaaat attttaaata tactatttta gataagttcc ctcttcatct
    13081 tgataaatta atcctttttt cataagcact ccaagagctc gtttaaaatt tttcttactt
    13141 gaattaaata atatagaaat atctttaggg tcagatttat cattaaatct catatatcca
    13201 tcagaacctt ctaaataact taaaatctta ttttctaaag tatcaagttc atcctttcta
    13261 tttcctctag gagaaagacc aagttttcca tcttcatata tttttatgac atgtaaattt
    13321 tcaagaacat caccagtttt tagttcagta aagtactcat tatgaagtat tacaccagca
    13381 tatttattgt ctacacatat cattgcagaa ttattagttt ggaatccata tacaactcca
    13441 gttacaatat ctcctacatt gtaagtatgg tctgttaata agtatgaatc tatgtctgta
    13501 gtagcagcaa ttcttttgct tttgtctaaa tatatataaa ataaatattt ttcgtctcta
    13561 aatagtggat aagtcttagc tttaaaagga actaatatgt ctttaggaag tcccatatct
    13621 ataaaagtac caatgtctgt attatcaact acttttaaat gtgctacatc cccaacctta
    13681 gctaaaggcg gtattaaagt tgcagcagtt ctgtcatcag aatctttaaa tatgaaagca
    13741 tttacttcat cacctatgtt tatttcattt tttccgatta atctattatg aagaagtata
    13801 tcgtcttttg tgttattagt ttgtccatcc aaaaaatatc caaattcagt ttttcttttt
    13861 actgtaagtt tattaaaatc acctatgttt atcaaattaa aatcatcctc tcattttata
    13921 tttataattt agccataata tacttatgta gtagtttgtc acagtatcca tattagtatt
    13981 agtgaaattt acaataaata atatagttat ttatgtattt ttcaattctc tagcttctta
    14041 tatagtataa actccaattt cttttttgtc tttaggtttt attaaaattt ttacaaaata
    14101 agttaaaaag tattgaaata aaatttcttt taaagtataa ttggtatata ccaaaattgg
    14161 tatataccat atcgaaaagt ggtgactata tgaaaatagt aaataaatct agtaatatac
    14221 cattgcatac tcaattaagt tcaataataa gagagatgat agaaactggt gagcttaaag
    14281 agggcgatgc aataatgcca gaaagagaac tttgcaacat acaaaatgta agtcgtatga
    14341 cagtaaataa aaccattgtt ggattagtta cagaaggact tctttatagg gtacaaggta
    14401 aagggacatt cgttgcaaag caaaaaaaga agtatcagtt ttcaaatgta aaaggtttta
    14461 ctgatgttat gaaagaaaag ggagtaaaca taaaaacgga tatattatcc tttgagatgg
    14521 aactaccaga tgatttagtt aaaagaaagc ttggaataag tgataatact acaaatatat
    14581 ataagattgt cagacttaga tatactgatg gagagccatt tggattagaa atagtatatc
    14641 tatcagaaga aatgtgtaag ggtctaacaa aagggatatt ggataattct tcattatata
    14701 gggttttaaa tgaaaaatat ggctataaga tacaaaaagc tgaacaggta atggagccag
    14761 taatactttc agatgaagaa agtaagcttc ttgaaacaga tgaaggtgct ttagctctta
    14821 aacttcatag aaattcctat aatagagaag gtagccctat agaatatacc atatcaatat
    14881 ttagaacaga taaatatcaa tatgaaatag tattgagtga gtaggtgaat aatatgaaat
    14941 gtttaattaa tggaaagata atattaaaaa atcaaatctt agaaaataaa gtattagtat
    15001 ttgatgaaaa aataattgat atagctgata gtgtaccaaa agattgtgaa gttatagatg
    15061 ctgatggaaa atatatatct ccagggctta ttgatattca tatacatgga aacatgggaa
    15121 aagatacaat ggattcgact gatgaatcta ttgaaacaat ttcaaagtca attatgagac
    15181 atggagtaac atcttttctt ccaactacaa tgactatgga taaagaacat gtttatgatg
    15241 cacttgaagt tattaaaaaa gcccaaaata gaaagcttga aggggcacaa gtattaggag
    15301 cacatttaga aggacctttt ataaatgaga attataaggg agcacaaaat gaaaaattta
    15361 taataaattc aaaatacgaa tttataaaag aatataaaga tgttataaaa gttataactt
    15421 atgctccaga aaaagatatt gattttgatt ttactagaga aataaaaaga tgtacagata
    15481 tagttttatc tattggtcat agtaatgcaa attatgacca agctaaagaa gctataaatt
    15541 taggagtaac taatgtaact cacatgttca atgcaatgac tggtttaaac catagagacc
    15601 caggcgttgt tggtgcagca cttacaacta atgtgtacag tgagttaata gcagatacaa
    15661 tccatataaa taaagattta tttcaattta tactaaataa taaaggaaaa gaaagactga
    15721 ttttaataac agattctata gaagctggtg gtcttgaaga tggcaattat tctcttggag
    15781 gtcagaaagt catagttaag ggtaatgaag ctagacttga aaatggagca ttagctggaa
    15841 gtgtgttgtc tttaaataaa atggtattta acttcttaga taatacaaac cttaaagtga
    15901 atgaagcaat taatttagct tctttaaatc cagcaacatc tttgggaata aatgacaaaa
    15961 aaggaagctt agaaataggt aaggatgcag atatagctgt atttgatgag aatttagatt
    16021 gtaaaatgac actttgcttg ggggacgtag tatataaaaa tatatagtat acaaaacaaa
    16081 ccttaaagac agtaaaaaca atataaaaaa taataaatta aacttacatt agtaaaagta
    16141 gtagttaaaa tttaggagga ataagatgag agtattagtg tgtaaagatt atgatggaat
    16201 gagtaaaaaa gccgctgaaa tgatagcagc tcaaatagtt ttaaaaccaa attcaatact
    16261 gggactagct acaggaagta caccagtagg tatgtataga gatttagtaa aaaaatacaa
    16321 tgataatata gtagattttt cagatgtgat gagctttaat ttagatgaat attataagtt
    16381 accaatatct aatgaccaaa gctatgatta ttttatgaaa gaaaatctat ttaatcatgt
    16441 aaacataaag ccagaaaata ctcatctacc aaatggaatg gctgatgata ttgaaaaaga
    16501 gtgtatgaac tatgaagctt ctatagatgc agctggtggt atagatgtac aagtacttgg
    16561 aataggtcgt aatgctcata taggttttaa tgaacctgat actaaatttg caaagagaac
    16621 tcatgtagtt gaacttacag agtctacaat agaagctaat gcaagattct ttaaatcaag
    16681 agaagatgtt cctaaaaaag ctgtaagtat gggaataggt tcaatattga agtctaagaa
    16741 aatattgctt ttagcttcag gagaagaaaa agctgatgca gtatataata ctgtttatgg
    16801 agatataact ccagaagttc ctggttctat acttcaactt cataaagaca ctatagttat
    16861 agtagatgaa gcagcagcaa gtaaattgaa tccaaaagat tataaattag tataagaata
    16921 gaatgtagtt taagtaaaaa atagctatca ttgagtaatc aaatttattt aatgatagct
    16981 atttttattt aaatttttta cttcttttta tttaaattag ttattattgt ttaaattact
    17041 tgcttattac tttttacgaa aactcgttat caagaagtat ccaaataaga tgttaaaaat
    17101 tattatgttt agtgggattc tatcaagcat aataaaatta cctataattg ggatattacc
    17161 aactggaaac ataaagaaga atacaggcat cagtgatagt aaaaaagatg gaaaacaaag
    17221 aagaagtaat cttggaatat caatatacca actaccatcc tttttgtatt ctctaatcaa
    17281 taattcagtt cctagtaata aaccaatacc accagaggaa attaaattaa taaaaatgta
    17341 tcttttaaag tcttgcatat aaccagtgta aaattgagta tagaaatcat aatttaattt
    17401 aacagctaaa aaatacataa gcaatagaat gattaaaaat aaaagatatc taagagcttt
    17461 tttcatttta aattctccct tcagaaatac tttattcagt tttattttgt tggaatctga
    17521 ttttatcatt tagtttaaga aatccataat attagtgaag aatgaaataa gtattatata
    17581 tgaataaata tttttagaat taaggtgaat tgtagtgctt aatataacta taatattaat
    17641 tgtttgaata ttcaataaaa agtttgaaaa atatcaattt tgatataaac tgaataaata
    17701 cagttgaata ttaaattatt attttatcaa aaatatgcaa agtactacac cttcaaatat
    17761 cacctaaagt aattaaaagg caattaaggt gaagtagttc aagtatttct aaaataagtt
    17821 taataaattc tataataatt tattttttgc cttaaaattg ccttaaaatc caaacaattt
    17881 taaaactaat gtactataaa aagctggtat aatttaaata tagtaaaaaa taagatttat
    17941 cttatctatt gggatttaat tatttaatca atatatttat accatttaat ttaaataaaa
    18001 agtctattaa ggagtgagct tatgagtaag ttaatttata tagcagatga tgaagataat
    18061 ataagaaatt tggtaaagac attcttaaaa aatgaaggtc atgatgttat ggattttaaa
    18121 acgggtgatg aacttttaga acaatttaat ataaaggagt gtgacttagt aatactagat
    18181 ataatgatgc ctggctcaag tggttttgaa gtatgtacaa aacttcgtga gaaaagtaca
    18241 gtcccaataa tcatgcttac tgcaagagat acagatatag attatattac agggataacc
    18301 ttaggtagtg atgattattt tacaaaacca tttagcccaa tgtctttggt tatgagagta
    18361 aaatctatat ttagaaggat agagtttgaa aagaaacaaa attatgataa atatagtaac
    18421 tcgatagata tggaattaaa atttggtgat gtaataataa ataaaaagaa taaaatcgtt
    18481 acaagtaaaa atgtaaatat agaccttaca ccaaatgaat ataacctatt gacttatttg
    18541 tttgaaaata tagatagagc agtttccaga gatgaattat taaacaaaat atggggatac
    18601 gatatagaag ttgagacaag ggctgctgat gatacagtga agagattacg taaaaaaatt
    18661 ttaaatacaa atattttaat agaaactgta tgggggtttg gatttaggtt gaaggagaaa
    18721 agttaagatg aagaatggaa atgacaagaa tagaattgga aagattaaat ccaaatttaa
    18781 attaaagttc tcaaagaaaa atataagcat aaaaactagg attttgttga gtatactttg
    18841 tttgataatt atagtattta tgataatatt agtatctttt aatgtatttc ttgatacata
    18901 tataaaaaca actgcgaatg aagaattgac aaagtctaca gaaatagtag aacatatgga
    18961 tagtaatttt agacctatta agccaccaca agatgatgga aagcttcctc ccaaagtatt
    19021 atctaatttt atgagaaatg tacaagataa agttaggatg gcagaaacac aatcagatgc
    19081 tgatgctatg gtagttgatt ctaagtataa cctgatattt ccaacaagag aggatgattt
    19141 cttaaaaaat gttgatgaga tggagctgat tagggagtgt attcaaaatg aaaaattaga
    19201 tttaaattca gatgaaaata cacggatatc taccagaaat aaggattatt atatttcaac
    19261 tgtaaaaatt actagtatat atggtgaaca agacaagtat cttatacttt ttatagacat
    19321 atcaaaaact ctaaatctag cacaaaagat aaatattgta ttaatatctg taatgtgttt
    19381 tgctggaata ttagcaatat ttacagctgt gattttatct gagaaaattg ctaaaccgat
    19441 aaaagagttg tgtgagtttg caaaaaaaat gggtcaagga gatttcaaaa gaacctactt
    19501 tgacttttca gataaagaat tagtagagct ctcaactgtt atgaataaga gtgctgagta
    19561 tctggataag tatgataatg aacaaaaaat attttttcaa aatgcatctc atgaattaag
    19621 gacaccactt atgtctatta aaggttatgc agaagctata aaatataatg ttatagatag
    19681 taaacatgca agtgatataa ttcttgaaga aagtgatagg ttaagtgata tggttgaaga
    19741 tttattatac atttctaaaa tagataatat aactaaagat tttgaacttg tagaatgtga
    19801 tttaagagaa gtactttcaa attgtggagc taggcaaaat gtaagagcta taaataaggg
    19861 gataaaattt atttatgaat ttgatgaaga aatggtttta tttgaatgtg atgaaaaaaa
    19921 catttccaaa gcatttatga atcttataga aaatgctttg agatacgcta agagtgaaat
    19981 aaaaatagtg tgtaagtata atcaaaaaaa tatagttgtg ataatagaag atgatggaat
    20041 tggaatcaag aaagaagatt tacctcatgt ttttgaaaga ttctataagg gagtaggggg
    20101 aaatcatgga attggattat caatagttaa atctattgta aataagcatg gtgggcgtat
    20161 atacgtagaa aatggcaaaa aaggagctaa atttactata ttatttaaat tgtaaaaaaa
    20221 ttagagaaaa tatagagatg tttgaagttg ttttttatat atatctgttg tatactgttg
    20281 aaaaaagaac aatattaagc tgacatatat tacgatagtt gacatttaaa gtaaatgctt
    20341 aaatatagat acgaaaggaa aagtaaaatc tgaagtgtat ttaggtttaa gtaagcttct
    20401 tattttataa aaaatatgta tgaaagaaca gctgattttt aatattacaa atttagtaac
    20461 ggttgtattt gaagcttttg tcatccatat gtttttatca gactttttag gtcagaaaga
    20521 agggtatata aaagttgtaa gatatgctaa actgggtttt ataatatgtt taggattctg
    20581 taatttaata actttaaacc ctaaaatcac aatgccttta attttcatcc ttattttttc
    20641 aacatcattt ttatataaag gaaatttaaa gacacgattg tttactactg ttttattaag
    20701 tatattcttt atactgtcag aaattgtagt tacaagtatt tttgttttat ttgtaaaaga
    20761 aggctttgaa ataatgcttg aaaataatag tataagagta ttggcgacaa ttttatctaa
    20821 aattgtcttt ttgttgactt gtaaaattat ttgtctattt aaaaaggatg tacatttaga
    20881 tatgcccata aagtattggc tccctttatt tttaatacct atatttagtt tatttctgtc
    20941 tgtttctatc tttgatgtaa gtaaattttt tagtcttgaa agtttaaaat ttctaagctt
    21001 aatatctagt gttggtattt tatatattaa ttttattgtc ttttatttat ttaaatttat
    21061 tatagataaa actaaactat ctatgaaata tgaactactt gaaaaagaaa taattcataa
    21121 ggaagaatta agacttagta atgagtgtta taaaattatt gttgaacaga ctgattctgt
    21181 cgttttcgaa tggaatatca aagaaaataa atcatttgta tcgcaggctt ggactgaaaa
    21241 atttggatat aacaatgcat gtaagaatat ttttaaagaa attaaagata aagacttagt
    21301 tcattctgaa gataaagcta tatttgaagg ttttcttgaa agtattaaaa aaaagaatat
    21361 gcacaatcaa gcagtatatc gtttaaaaaa atctaatggt gaatatattt ggtgtagaac
    21421 atcaattaca agcatttata atgatgaaaa tgaactttta agagttgtcg gagtaattgt
    21481 agatgtagat agtgatataa aaaaatatga agagttaaga actagagcag aaagtgactc
    21541 attgaccaat atatacaata aaggtacatt tgaaaaatta gtggaagaaa ctatagttat
    21601 gaatacaggt gataaaaaag atgcattatt cattattgat ttggatgatt ttaaagaaat
    21661 aaatgataat tttggtcatc catttggtga ttttgtacta aaaacatttg ctgataagat
    21721 acaaactagt tttggtagta aagacttagt cggaagaatt ggtggagatg aatttgttgt
    21781 atatatgcaa gattatgtta cagaagtaaa tttgcataaa aaagctaaag aattaaatag
    21841 agtactttcg gataattaca ctgatttgag ttttagtttt gatgcttctg tcagtatagg
    21901 tattgcaagg tatcctcaag atggaacttc attttttgaa ttgtttaaaa atgcagatag
    21961 agcactttat agcataaaag catcaggtaa aaattcatat tgtttatttg aagaagaact
    22021 atatgtacag tgaatttgaa tttagatttt atgtgagagt aagatttata tatacttgtg
    22081 gctgtctgat ttataaaata tgttactttg tatattttta tatgtttcag taaggttaat
    22141 taacatgagc aaaggtgtaa gtaaatttat attagtttaa gtttacttac acctttataa
    22201 aaatacaaat aatagattca tttacattct taaatgatta aagctcttta ccttctaaac
    22261 atgcataaca tatcgttata attccagtaa ataagactaa aatgcccatt actaagatta
    22321 caatttcatc atctattact ccaaatgttt ttaaagtaac ttatttcgct ttgtatcata
    22381 ataatttgtc tctttttaca ttttaacttc tgctgagatt tgagttagat attcattaga
    22441 atctcgcaca cttatatcat atagaagata ttcttcataa acaaaatccc caatacgtaa
    22501 attattctga ttaaaaaaat ttaataactt ttcataagcc ttgtaaatag tttcataact
    22561 ccctttatga taagcagtta cataaagtcc ctttggtttg attgatacag gatatttctt
    22621 gtactcttta ttaacttttg taaataaata tgaatatgat tcaaagtctt tattaattat
    22681 atcttcacct ttaatgattg agccaatcgt accataatca ctcaattcat agttgtccat
    22741 aaagttaata cattcatata aaaaattttc ttcctcatct cctaaaaact gttctttata
    22801 tgtaacaggt gttttgacca agtactcttc ttcatgttct tttaaagtaa tagtattcgc
    22861 atctatatta catgcacttt tagtaaatga aatagtagat tccattagag cttgaatatt
    22921 atttagtttt tcaatttcat ttttaatatc aatggttttc ttttctaaaa gctcaattag
    22981 taaattaggt gttcttttgt ctatataagc tttaatttct tttaaaggca tttttacttc
    23041 cctaagtgaa gaaattatac caaaaatgct aagttgatgg tatgagtagt atctatatcc
    23101 attttctttc tttaattctg gtgagaaaag acctatatca tcataatgga aaagtgtttt
    23161 tttattgatt ccacaaatct ttgcaaattc tccagttgta aaataatttt ttgaaacttg
    23221 actcataatt ataattcctc cttgactatc ctgttacagt atagtttatc atagtatttt
    23281 gtaaaggagt gtgattatat gaaaaaatta attcattttt taaaaccata tagagtttta
    23341 attgttgtag ttttgatatt tacgttttta caaacacttg gaactttgta tataccaaca
    23401 cttacagcaa atatagtaaa taatggtgta gtaaagggag atatagatta tattgtaaaa
    23461 acaggtttaa tgatgatgat agtagctggt ataacagctt tatcagctgt gttagtttgt
    23521 aaagtatcag caaatctttc atctggattt tgtagagata ttagagaagc agtatttata
    23581 aaatcacaag atttatcaat aaatgatttt aataatatag gtacagcatc aatgattact
    23641 aggagtacta gtgatattac tttaataggt cagtctgtgt ttatgtttat tcaattagta
    23701 ttaccagcac caattataac tgtttctggt ctattcttag catattctat agataaagca
    23761 atgacaatta ttattgttgt agtaatgttt ttattcatgc tttcagcatt tttagttggt
    23821 aaaaagctta taaagttgtt taaaatgatg caaataaaga tggataatat gaatagggtg
    23881 ttacgtgagg tagtaactgg agtaagagtt ataagagctt ttaataggag tcgttttgaa
    23941 aaaaagagat ttgatagaac tgcaatagat tattctgaaa cagcaatttc aataaataaa
    24001 atatttgcag tacttatgcc tattgtaatg ttaataatga atttaggtat agtaagtatt
    24061 atttggtttg gtgggatgag agtcagtaat ggaaatatgg aaataggtca tataatggca
    24121 cttgttgaat attgtatctt aattttattc tatttaatca tgggagtaat ggtatttatg
    24181 tacataccta gagcaggtgc atgtgcagat agagtaaatc agatattaga tatagaacct
    24241 gaaattgtag atggaaatgg tcataaagat actgtctcag agagaggaca tttagtattt
    24301 aaaaatgtaa ccttttcata tgcacaatca gaagaacctg tgttaaataa tataacattt
    24361 gaagcaaaat ctggagaagt aactgcaatt ataggaagca ctggctcagg caaatctact
    24421 attgcaaata taataccacg tttttttgaa attcaatctg gagaaatatc tataaatggt
    24481 caggatatta agaagattcc tcaaaaagaa cttagagata agattggatt tgtaccacaa
    24541 aaagcttttt tatttagtgg aacaatagaa gaaaatataa ggtatggaaa agaagatgca
    24601 agtattgaag aagtaaagca tgctgcaagt atagctcaag ctgatgaatt tatttatgat
    24661 atggaagaca agtatgactc atttgtagca caaggtggaa ataatttgtc aggtggtcaa
    24721 aaacagagaa tatccattgc aagagcgtta gttagaaagc ctgaagtata tgtctttgat
    24781 gatagttttt ctgcattaga ttttaaaaca gataaaagac ttagaaaagc gttgaaaaat
    24841 gaaatcaaag attcatcagc tataattata gcacaacgta taagtacaat catggatgct
    24901 aatcagatta tagttttaaa tgatggaaaa attgtaggta ttggaaaaca taaagattta
    24961 cttgaaaatt gtgaagttta taagcaaatt gcggattcac aacttagtaa agaagaactt
    25021 gcataaaatg aagaattaat ctgatatttg gaggtgtatg atatgagtga aaaaagaata
    25081 gatgaacaag atatagaagt acttagtttt gaagatggca tgtcagcaga aaaagctaag
    25141 gatgcaaaaa aaactactaa gagattatta aaatatatgg caaaacaaaa gtttaaaata
    25201 ttaattattt ttatttcagt attgataagt tcagcgctta cagttttagc acctatggtt
    25261 atgggaaaag ctattgacca actatttaat ggaataaaaa ctgcagtcca aacaggtaca
    25321 aaattcagtg tgaattttag tactatggga gggatagtat caatacttct agggttgtac
    25381 ttaattagtg cagtatttat atatattcaa cagtatatta tgtcaggagt tgcacaaaat
    25441 ctagttctta gcatgagaaa agatttaagt gataaactca ataaacttcc tcttaagtac
    25501 tatgattctc ataaaaaggg ggaaacactt agtatagtaa caaatgattt agaaaaagta
    25561 gcagatagtt tacaagaagg attaatgcaa cttattacag cagtagttac agtagttggt
    25621 tctattgtaa tgatgataag tataagtgta ccacttacaa tagtatcagc tataacatta
    25681 cttgtttcat tgggtattac tgttgtaatt gcaagaaaat cacaagaaag attctctgaa
    25741 aatcaaaagg cactaggaga gttaaatagc aatatagaag agatatttac tggtcaaata
    25801 gtggttaaag catttagtaa agaaaaggat actataagaa actttaaaat attaaatcaa
    25861 aatctttata atgcaagtag aaaagcacag ttttcgtcat atgcaatatc tccaattatt
    25921 agatttataa acctaattgg ctatgttatt atagcagttg taggtgggat atttgcatca
    25981 actggagcaa tgactcttgg tagtatacaa gcgtttattc aatatgtaaa tcaagcatca
    26041 gagcctacta cagaaatatc ttatattgta aatatgcttc aagcagcaat agcatctgca
    26101 gagagagttt ttacagttat ggacgaggtg gaagagataa aggatgaaga atcttcaaag
    26161 gttattagca tgcctaaagg taaagtacaa tttgagcatg ttaaatttgg atatagtgat
    26221 gattttattc ttatgaaaga tattaatatc aatctaaatg caggagataa gattgcaatt
    26281 gttggaccta caggagctgg aaagacaact cttgtaaatt tacttatgag attttatgag
    26341 atacaaggtg gaagaattac tattgatggt gttaatataa aagatttaaa gcgtggagaa
    26401 cttagaacta tgtttggtat ggttcttcaa gatacatggc tgtttaatgg aagtataaaa
    26461 gaaaatattg catatagtaa gtcagatgcc acaatggatg aaattgtaag agcagcaaaa
    26521 tcagcaagag tagaccattt tataaggact ttaccacaag ggtatgacac tatattgact
    26581 gaggatgctt ctaatctatc tcaaggtcaa aagcaacttc taacaattgc cagggcaata
    26641 ctttcagacc catcagtatt gattcttgat gaagcaacat ctagtgtaga tactagaaca
    26701 gaggtagaaa ttcaaaaggc aatgaataac ttgatgaagg gaagaactag ttttgttatt
    26761 gcacatagat tatcaactat tcgagatgct gatttaatat tagtaatgaa agaaggaact
    26821 attattgaac aaggaagcca taaggaactt attgaaaaga aaggattcta tgaagaactt
    26881 tataacagtc aatttacaag tgaatatgat gaagatgttg tatgattatc aagttttagg
    26941 caactaaatg attgataaat attaagttaa atatagtaac atgtaaggtt atatggaata
    27001 agagtatttc tctatttcat ataacctttt ttatttatca aaataagata aaatttcctt
    27061 tctaaattag attgaagaat gtatttatca atataaaagt aaaataatca ttattattag
    27121 tgaagtaaat attgtttgcc acatatatgc cataaagatg cacttatttt acggagattt
    27181 aacaaagtag tgtaaagtat actctaaata taaaataaat caaatagagt taaataaatt
    27241 gagaggtgat ataaatagtg aataaaaaat tgaactatag atttgaaatg aagcacaaaa
    27301 taactgaagc agatgtgtta gctttaaaat caagactcta tccaataatg aagaaagatg
    27361 aaaatgcatc taaagatgga aaatatctta ttaggagttt atattttgat actcctgaag
    27421 ataaagcact tttggataaa ttaaatggcg ttgcaataag agaaaagttt aggataagat
    27481 tttataataa tgactgctct tatataaggt tagagaaaaa aatcaaacat tacaacatga
    27541 catcaaagct atcaactaat ttaaccaaaa aagaagtaat aaatatacta aataatgata
    27601 ttgaatttct aaaagagtcg acaaattgtt tattaagaga attttatttg aaattaaaat
    27661 gtgaaagatt agaggcaaaa agcatagttg attacaatag agaagctttt atttatccag
    27721 ttggaaatgt aagagttaca atcgatagtg atattaaaac ttctgtaaat tcggtagatt
    27781 tatttaataa agatttgcca actatttcgg taattgatga gaatatgact gtattggagg
    27841 ttaaatatga tgaatttata ccagatttta taaaggattt aattcaaatt aataagacta
    27901 cctctacagc agtttcaaag tatgcttcaa gtagattata tatttaagaa taaaggctat
    27961 gatttatata aagatataca taaataaggt taaaaaacaa ataagttaaa aataaataaa
    28021 ataaaaaata aataagttaa aaataggaag gatgatttta attatgacat ttaatgatat
    28081 ttttaaatca agttttatag aaaacgtatc aggtttttca tttgtggaca gtgctttagc
    28141 actaggttca gcttttttag taggtttgtt tatatatatg gtctataaaa agacttatat
    28201 gggaattatg tattctcgac cattcaatgt gtcgcttgta gcacttacaa tgcttacaac
    28261 ttttgtaata ttggcggtta cttcaaatgt agttttatcc ttaggtatgg ttggtgcttt
    28321 atctatagta agatttagaa cagcaattaa agacccaatg gatttagtat ttctattttg
    28381 gtcattaggt tcaggtatag ttttaggagc aggtttgatt cccttagctg tcatgggttc
    28441 aataattatg ggattgattc taatattctt ttcaaataaa acaatatctg aaactccata
    28501 tatattgatg gtaaattgta ataatgaaga ttcagaagat atagcaactg ataaaattaa
    28561 aaaagtattt actaaatatc aaataaaatc aaaaagtgtt acaccagaaa aaggaataga
    28621 attagtgttt gaagtaagaa tgaaagatgg agaaacaagt cttataaatg acttgagtca
    28681 agtagatgga gttactaatg cagttcttgt aagttataat ggtgactatg tagcatagag
    28741 aggagtaatc ttttatgaaa gataaaaaat ttacccttct tatctcgatt atgattatat
    28801 ttttatgtgc tgtagttgga gtttatagta catctagcaa caaaagtgct gatttatata
    28861 gtgatgtata tattgaaaaa tattttaaca gagacaaggt tatggaagtt aatatagaga
    28921 tagatgaaag tgacttgaag gatatgaatg aaaatgctat aaaagaagaa tttaaggttg
    28981 caaaagtaac tgtagatgga gatacatatg gaaacgtagg tataagaact aaaggaaatt
    29041 caagtcttat atctgtagca aatagtgata gtgatagata cagctataag attaattttg
    29101 ataagtataa tactagtcaa agtatggaag ggcttactca attaaatctt aataactgtt
    29161 actctgaccc atcttatatg agagagtttt taacatatag tatttgcgag gaaatgggat
    29221 tagcgactcc agaatttgca tatgctaaag tctctataaa tggcgaatat catggtttgt
    29281 atttggcagt agaaggatta aaagagtctt atcttgaaaa taattttggt aatgtaactg
    29341 gagacttata taagtcagat gaaggaagct cgttgcaata taaaggagat gacccagaaa
    29401 gttactcaaa cttaatcgtt gaaagtgata aaaagacagc tgattggtct aaaatcacaa
    29461 aactattaaa atctttggat acaggtgaag atattgaaaa atatcttgat gtagattctg
    29521 tccttaaaaa tatagcaata aatacagctt tattaaacct tgatagctat caagggagtt
    29581 ttgcccataa ctattattta tatgagcaag atggagtatt ttctatgtta ccatgggatt
    29641 ttaatatgtc atttggtgga tttagtggtt ttggtggagg tagtcaatct atagcaattg
    29701 atgaacctac gacaggtaat ttagaagaca gacctctcat atcctcgtta ttaaaaaatg
    29761 agacatacaa aacaaaatac cataaatatc tggaagagat agtaacaaaa tacctagatt
    29821 cagactattt agagaatatg acaacaaaat tgcatgacat gatagcatca tatgtaaaag
    29881 aagacccaac agcattttat acttatgaag aatttgaaaa aaatataaca tcttcaattg
    29941 aagattctag tgataataag ggatttggta ataaagggtt tgacaacaat aactctaata
    30001 acagtgattc taataataat tctaatagtg aaaataagcg ctctggaaat caaagtgatg
    30061 aaaaagaagt taatgctgaa ttaacatcaa gcgtagtcaa agctaataca gataatgaaa
    30121 ctaaaaataa aactacaaat gatagtgaaa gtaagaataa tacagataaa gataaaagtg
    30181 gaaatgataa taatcaaaag ctagaaggtc ctatgggtaa aggaggtaag tcaataccag
    30241 gggttttgga agttgcagaa gatatgagta aaactataaa atctcaatta agtggagaaa
    30301 cttcttcgac aaagcaaaac tctggtgatg aaagttcaag tggaattaaa ggtagtgaaa
    30361 agtttgatga ggatatgagt ggtatgccag aaccacctga gggaatggat ggtaaaatgc
    30421 caccaggaat gggtaatatg gataagggag atatgaatgg taaaaatggc aatatgaata
    30481 tggatagaaa tcaagataat ccaagagaag ctggaggttt tggcaataga ggaggaggct
    30541 ctgtgagtaa aacaacaaca tacttcaaat taattttagg tggagcttca atgataataa
    30601 tgtcgattat gttagttggt gtatcaaggg taaagagaag aagatttata aagtcaaaat
    30661 aagattaaaa ttgaatataa ataattttaa tactgttaag tctaaatatt tacttagcag
    30721 tattttttta gaaaataatg tatttggtta ataatataag gtaataaatt gataaaaatt
    30781 aaatacagca tattaataat acataataaa gtaataaaaa aactgtttaa gtataataac
    30841 ttatatttag acagtttttt tcatttataa ataatataaa tgaaattgaa aacatttgaa
    30901 ggatagaaat tggttggata aatgtataaa ttacttcacc aaaaaataat gacaaaaatt
    30961 gtaactaagt tgtaataaaa tggtagttat ttagcataaa ataatgtatc atagaagtat
    31021 attataaaat taataaaata agatttttgt aagaaaactg ctggcttttg atatttagag
    31081 tgagtagtta aattatgttt aggaggggta gaatttgttg caaaaagtat tatggaaatt
    31141 tttaaagcta gtagtcggtt tatttatatg ttcagttggt atagtattga cgataaattg
    31201 taaccttgga ttatctccct gggatgtatt tcatcaagga ctttcaaatc atataggaat
    31261 aactatagga actgcttcta taattgtagg ctctatagta gttattgctg atgtcgttct
    31321 tggagaaaat gtaggatggg gaactgtttt taacatgcta ctaattggat tctttatgga
    31381 tttactttta tatagtaatt taattccaga ggctgatagt ttatttgtag gaataattat
    31441 gttgatatta ggattggttc ttttgtctgt tggaatggta ttttatatgg gaagtggttt
    31501 aggaagtgga cctagagatg gtttgatggt tgcaattcaa aagaaaacag gaaaatcact
    31561 taaattaata agaggtacta tagaagttgg agcattaata gtaggatttt tattaggtgg
    31621 aaaagttggt ataggaacta taataagtgc atttggattg gggtatttca cacaaatggt
    31681 atttggctta tttaaattag attgtagtaa gattaaacat agatttatag tagatgatat
    31741 aaaatttatc aaagtgtata tgagtggtga gaaaaaagct gctgttcaaa atatagttaa
    31801 gtaatttaag aataaattca acgaaatgtt aagtatttta aattaacatt ttgtttagat
    31861 agataaattg aatattaaaa gaatattaaa atatgaggat tgctagaaca ctataaaata
    31921 tagatttcta gcaatttttt atttgttcaa tattttttta gtactagaag tcttattctc
    31981 tatttaatga atgaattaat ttataattag agatactaaa ctttatagat attaatataa
    32041 acacctttaa actgtgtatt ttccaaagcc tttaaaatgc ttgtatttat tctaaataaa
    32101 aaaataaaaa aatgtcaaaa aaactcttgt attatatcca aattttatat ataattacct
    32161 atgttgttta gaaattttaa actcaatgtt tagtaaacaa aatgtttagt aaaataaaac
    32221 agaaactagg aggtgcaaca tggatatagg tgaaaagata aaaagattaa gaacagaaaa
    32281 acaactgacc caggaagagt tagctaatag atgtgaattg tcaaagggat ttatttctca
    32341 attagaaaat aacttaacat caccatccat agctaccctt atagatatac ttgaaatact
    32401 aggtacaaat ttaagggaat tttttaatga aatagatgat gaaagaatca gttttacaaa
    32461 agaagatatg tttgaaacag aagatgaaga tttaaaatat aaattaaagt ggttaattcc
    32521 aaattcacaa aaaaatgaaa tggagccaat aataataaca ttgtatccag gaggacagta
    32581 taaagaagaa aagccacatg aaggtgaaga atttggatat gtattagcag gttcaatata
    32641 tgtccatata ggcgaaaaga aaaataaagt aaaaaaagga gagagttttt actttagacc
    32701 gaaagcaaat cactatatat caaacgaggg caaaactaca gcaaaagtga tttgggtaag
    32761 tacgccacca tcattttaga atagaggtgt ttaataattg gtagaaaata taatagaatt
    32821 aagggatata tctaaacatt atgaagaact tactgtttta gataatttca atttagatat
    32881 aaagaaaaat gagtttctaa cattacttgg accaagtgga tgtggaaaaa ctacaacatt
    32941 aaaaataata gcaggatttg agtatgctga tgatggtaaa gttttatttg aaggtaagga
    33001 gataaataat ttgccaccat atgaaagaca agtaaacaca gtatttcaaa aatatgcttt
    33061 atttccacac atggatgttt atgaaaatgt agcttttgga ttaaaaatta aaaagactcc
    33121 aaaagatgta atagatgcta aagtaaaaga ggttttgaaa cttgttgcac tagaaggttt
    33181 tgaaagacga caagttgaat cattgagtgg aggacaacaa caaagaattg caatagcaag
    33241 agctctagtt aatgaaccaa aggtattatt actagatgaa ccacttggag cacttgattt
    33301 aaagttaaga caagagatgc aaatagaatt aaagagaatc caaaaaaaat taggaataac
    33361 atttgttttt gtaactcatg accaagaaga ggctcttact atgtcagata ctattgttgt
    33421 aatgtataag ggcaaaattc aacaaatggg aacaccacaa gatatataca atgaacctaa
    33481 aaattcattt gtagctaagt ttataggtga aagtaacata tttgatggaa ttatgataga
    33541 agattataaa gttaatttct gtaatagaga ttttgagtgt gttgataaag gattcgaaaa
    33601 aaacgaaaat atagaagtag taataagacc agaagatata aaaatggtaa agccagaaga
    33661 aggaatgtta aaggggaaag ttacatctac agtgtttaaa ggagtgcatt acgagataga
    33721 attgaatgaa aatggaagat tgtggatact tcataatact aaaaatgctg aggttgggac
    33781 tgaactaggc atggatatat atccagaaga tatccatata atgagaaaag agaataacta
    33841 agatgaaaag aaaatctttt ttagcatatc catatgtagt ttggagtgcg atatttgtaa
    33901 taattccttt aatattagta gtatttttta gttttacaaa agaatcaggt ggaggttatg
    33961 cctttacact tgagaattat aaagaagtaa ttgaccctat atatatgaaa gtttttgggc
    34021 gttctattct tttagcagga ggagctacat taatatgcct tatagttggt tatccagtgg
    34081 catatataat ttcaaaggct cgtgtaagta gaagaggttc attaatatta ttgtttattc
    34141 ttcctatgtg gatgaacttt cttttaagaa catatgcatg ggttgctata ttaggaaaaa
    34201 atggactttt aaatacattt ttaggttggt ttggaataca accattagca attttgtata
    34261 ctaattttgc catactttta ggtatggtgt ataacttttt accatttatg gttcttccaa
    34321 tatatacagc actatcaaag atggataatg atttgataaa cgctgctcat gacttgggtg
    34381 caaataatat gacagttttt agaaaaatta tatttccttt gagtttgcca ggtgtaatgt
    34441 ctggaataac tatggtattt atgccagcag tcactacttt tgcaatatca agactgttag
    34501 gtggaggtaa aataatgctg gttggagatt tgattgaaca acagtttaca gttgttggag
    34561 attggaactt tggttcagct atatcgatat ttatgatgat agtaatatta atatctatgt
    34621 ctataatgtc aaaatttgga gatgaatctg acaaagaagg cggtgggtta ctattttaaa
    34681 attaaagaaa ataacttcta atatatattt agcattagta ttcttatttt tgtatgcacc
    34741 catatttgct ttggtactat tttctttcaa tgattcaaaa tcaatggcaa gatggaatgg
    34801 atttacatgg aagtggtatg gtcaattact tcaaaatgag agtataatga gtgctttata
    34861 ttatactatt gtaatagcta tattagcgtc tgtaatatct acaatagtag gaactataag
    34921 tgctatagga atacataaga tgagaggtaa gagtaagaaa ttaatactaa atgtaaacta
    34981 tcttcctatt ttaaatacag agatagttac agcagtagct cttatgagtc tgtttgtatt
    35041 tgtaaaaatg gaatttggat ttacaacaat gctattggca catataatgt tttgtttgcc
    35101 atacgttata ctttcagttt tgccaaaaat gaagcaatta cctgataata tagaagatgc
    35161 agctatggac ttgggagcaa cacctatata cgctcttaga aaagtaattt taccacaaat
    35221 aaaaccaggt atagtttctg gatttttaat tgcatttact atgtcaatag atgactttat
    35281 aataagtttc tttaatgctg gaaatggtgt aagcaatctt tctatagaaa tctatggaat
    35341 ggctagaaga ggtataaaac ctgaaataaa tgcattatca acaataatgt ttgcagtggt
    35401 tctaggttta cttttactag ctaataaaaa agaatctata gtaaggggga ttaaataatg
    35461 attaagttta aaaaagcaat atcccttata gctgtaggta tgatgacagt tactttattt
    35521 acaggatgta ataaagcaac tgattctaca aaagttttaa atgtatataa tgttggagat
    35581 tatatagatg agtctcttat agataagttt gaaaaagaaa caggaataga tgttcaatat
    35641 tcaacttatg atactaatga aatgatgtat caaaaagtaa agagtggtag tacacactat
    35701 gatttagtat ttccttcaga ctatatggta gagaaaatga aaaatgaagg tcttttggaa
    35761 aaattagatt ttaagaatat acctaatatg aaatatttag ataagagttt tttaaatcct
    35821 gtatacgaca aaactaatga atatagtgtt gcatatatgt ggggaactct tggaatactg
    35881 tacaataaga aagaagttaa agaccctatg gatagctgga atatactttg gaatccaaag
    35941 tataagggaa atataatgat gtttgactct gttagagata ctatagggat aactcttaaa
    36001 aaattaggat atagcatgaa tagtgtaaat ccaaaagaaa taaatgaagc taaaaatctt
    36061 ttaatgaaac aaaaggattt agtattggct tatgtaaatg atgaaggtaa ggatagattg
    36121 cttggtggag aagtggcaat gggtatgctg tattctggag atgcagttac actaatggag
    36181 caaaatcctg accttgatta tgctatacct aaagagggaa ctaataaatg ggtagatgct
    36241 atgtgtgtac ctacaacagc acaaaataag aaagaagctg agctgtttat aaacttttta
    36301 ttagacccag agaatgcaaa agtaaatgct gagtacattg ggtattcaac acctaataca
    36361 ggagcactaa aattattaga cccagaaata actcagaatc ctgttgcata tccatctaaa
    36421 gaagtgcttg ataaatgtga aacttttgaa gatattggtg aaaatataaa attatatgac
    36481 aaggcttgga tagagttaaa atcaaaatag ggtcttgttg gtttaagtaa atttacttaa
    36541 taaatactta ataaaactgt tcttttttag aaaatttatt ttctaattat tgaacagttt
    36601 tattttttgt ttaagttata ttcatatgca atttaaatag tttattaata aatgaaaact
    36661 tatttgtata atgactttaa taataattag aaaaaatggg caacttaata gaataattgg
    36721 aggtgtaaat ttataaaaaa tgaataggat aaataaaaaa atagatttat taatattggc
    36781 tttgctcgtt tttatatttt taattgttgg aatagtaata ctatcgatta ggacagaaaa
    36841 taaattgaat gtgttcataa tgttagcaat aatttttttt ataataatgt taacttattt
    36901 atcaaattca gtagtggggt tgataacaag ttcaataatt atatttatgt atacatccta
    36961 tattttatat aacaatatta ctcacaatat ggatgttgaa tttatatcat atatgtggat
    37021 aatagcaaca ccagtatctt caattataat gggtaatctg aacaaaagca taaatgaatt
    37081 gcaaaataca aataaaaaac tatctgaaca gtataaggaa ttagtgacta ttgatagtga
    37141 aactggactt agaaatttaa agatttttta taatgatgta aatatggaga taagtaaatc
    37201 tattagacat aatactgatt tttctcttat gatagtaaaa ttaccatact acggaaacct
    37261 acagactata tttggtgaaa acaaaactaa taaaatagta aaatatattg gttcaaatat
    37321 tatagaatgt acaagaaatg aagatataat ttatagttta caaaaagata tgatagggat
    37381 actaatgcca aatacatctt tggaaggttc aaaagttgtt aaagacagaa taaagaaaag
    37441 gataaaagaa ttaaatttag atttaaacaa taggggaaaa tatgtaaata tagatgtcaa
    37501 aattgcattt ttacaatata agagtagttt tggagatagt ataaatttta agaatatagt
    37561 tgaagaggaa cttcaatatg atgtttaaaa tatttaataa aagtctatta aaattagtag
    37621 ttgtattatc aatagtactg acaatatcaa attttagctt atcttcatat gcatcagaaa
    37681 ttacttccag cacagataag gtattaatca tatatgattc taagaaagaa acagcttata
    37741 atagagatat tttaaatatt atgaggactc tattgggaag atttagttca gatatagagc
    37801 tattaaaatt gagtaactat gatggtgaga taaataaaaa ttattacagt catatattta
    37861 ttttaggaat caatgaaaac tcatataata atgataaaaa cactaaaaac ttgattagtt
    37921 ccttaaattt atataaagga actatatgtt ggttaggata tggtatagaa aatcttttgg
    37981 aacataaaaa atacaattta gactatgtag gaaaaacaaa caatatagtt agtgtaaatt
    38041 atagaggtaa atcatataac ttggatgaac attatgtttt taacattgta gaatcaaaag
    38101 atacaagtaa taaagtaata ggaagtatta atgatacctt aaataagtat ccatatataa
    38161 taaatgataa aaatcttttt tatgtatcaa aattagattt agatggagtt ttattttata
    38221 tattttgcga ttcacttaat gatattttta atattaagac gtttgataaa ggacgtatat
    38281 ttgtaagaat agaagatgta catgctttta gagaaccaaa aaatcttgta gagatagcgg
    38341 attatttaag tagtaagaat ataccattta cgattgcatt aataccagca tatgtaaatc
    38401 ctaaaaatca taaggtaata actttatcag aaagccctga aattgtcaaa gcaataaaat
    38461 atatgcaaga taaaggtgga actgtgatat tgcatggata tactcatcaa tacaagaaag
    38521 aagaagtttc tggagaaggg tatgaatttt gggatggtaa aaaagatgaa cccttaaaag
    38581 aaaatatgaa gatatttgtc aaagatagag ttttgaatgg tcttagagta tgtatagaga
    38641 atggaattta tcctcttgca tttgaagcgc cacattatgc aatggaatca gagggatata
    38701 aagaattaaa aaaatatttt tctacttata tagggcaaca tcaaaataat gataaaaaat
    38761 ttagcacaaa tacatatcct tatattatta gggatacaga ggagtttaat atatttatac
    38821 ccgaaaattt aggatatata gacccagaag ataagtttac ttttcaaaat ataaaagaaa
    38881 atttagataa attatccatt gtaagaggtt ttagtggagg gttcttcttt cattcatatt
    38941 taaacataga gtatctaaaa aacacaatag aatatttaga aaaacagaat atagaattta
    39001 tgaatttaag agattttaat aattgggtaa aagttgatga aatacaaata agaaataatg
    39061 gagatgaaat tatagtcaac tatgataagg acttagatga actaactaaa agtgatacta
    39121 gatttaaatc catatccaat attagtaaag ttttaatatt catagtatct ataagtgttt
    39181 taatatttgt gattatattt atatatttta agagaataga taaaaagaaa tttttaaaat
    39241 aaaggatttt atattagaat caatatttta aaatatttta ggagaaattt atgagagatt
    39301 taaatgtatc agagtatttg ttcgtattta gtttgtttag tatatggtct ttattgctta
    39361 taaatattat tttagctatg ggtggatata tattttattt taaaaacttt gataaagaaa
    39421 taaaagaaat tgatgaatat cctatgatat caatacttgt tcctgctcat aatgaagcta
    39481 aagtgatagg tagaactgtg gagtctttgc tattactcaa ttatcctaag agtaagatgg
    39541 aacttattgt tataaatgac aattcttctg ataatagtaa agaaatttta gaaaatataa
    39601 aggataggta caacaattat aatttcacta taataaatac agatagttta acaggtggaa
    39661 aaggaaagtc taatgcatta aatattggat atacgatttc aaaaggagat tttatagctg
    39721 tttatgatgc agataacaca ccagataaaa atgcacttag atatctagta caaactatag
    39781 taatgaatga tgaattaggt gctgttattg ggaaatttag gactcgaaat aaaaataaaa
    39841 acctattaac caaatttata aatatagaaa cattaagctt tcaatggatg tcacaagctg
    39901 gtagatggca actttttaat ctatgtacaa taccaggaac taactttata ttgaggagaa
    39961 gtatcataga agaaattgga ggatgggata gtaaagcaat tgcagaagat acagaaataa
    40021 gttttaggat atataaattg ggatacaaga taaagcttgt accacaatct ataacatggg
    40081 aacaagagcc agaaactgtt aaggtgtgga taaagcaacg tactagatgg gcaaaaggga
    40141 atatatatgt attaatgaaa tatataaaaa atatatttaa acagggaaga aataagattg
    40201 tgtttgatat agcttacttt ttttctgtat attttctatt tttaacatct gtaattatat
    40261 ccgatatttt atttgtttta agtatatcta aactagtaga aatttctatt ccaattaact
    40321 tttttctaat atggatacta tcttatcttt tatttattat agaagtgagt ataagcctta
    40381 ctatagaaaa aggtgaagca acaattgaaa atatattcat agtggcaata atgtatttta
    40441 catactctca actatggctg tttgtagcta taaaaggaat gatagagtat ctaaaagata
    40501 taatttttaa aagagaggtt aaatggtata aaacagaaag attttgattc atgtacagga
    40561 ggaattaaca tgaaaaaatt tattatatca attatatctt tagtattgtt tttttcaaat
    40621 atatcactta tatacaaagt aaatgctgat gagactaaag ttaaaaatta taagtttgaa
    40681 agagatataa ctattgatgg tgttatagga agtaatagta ctttttttga agtaaataaa
    40741 aattgggata ttgaagaagt tttattgcat cttaatttta gtaagagcca aatattaaat
    40801 ggagatgttt caagtttaac tgtattgata aataatgtac caataaaatc tattaaatta
    40861 aatgctaaga caaattataa aaatacatta gaagtattag ttccaaaaga ttatataatt
    40921 caaggatata atgaaataaa aataaaaaca tacaaaacaa tatctgataa aatttgccaa
    40981 gatgattcca atactgggaa ctggatggtt attcacaaag aatcatatat atcaattaga
    41041 tataagcaga aaaaggtgga aaactcaata aatgaatatc cgtatccata tgcagaaatt
    41101 gaaaataatc ataaattaga tacaactata gtagtaccag ataatatgac tagaggagag
    41161 actacagcag tgtttaattt ggcatcagca tttggaaaaa taacaaaaaa tgatgattta
    41221 aagttagatg ttaaattata ttcagaaatg aaaaattggt cagatgataa tattatatat
    41281 attggtaaac ctgaaaatac agcagaagaa attttggata ttttaagtat aaaggaacaa
    41341 accctattat cttcaaactg tataatcaag caagtagatt caccatacaa taagaataag
    41401 aagatgatgg tggtaattgg tagtaatgaa gatgatttaa taaaggcatc aaatttatta
    41461 atagaaaata gactttctaa ccaagtttta tcatcatcag tacttgtaaa caaagagact
    41521 aatataaaaa ttaataggga acaaaaatta aatttaggtc atttaacatt aaaagattta
    41581 ggatattctg actttttgtt ggaaggagca tttaatcaac aagctttgtt tgatgtcaaa
    41641 ataccaacgg gtaaggtatt agatgatggt tcaaagatta tcttaaattt aagatattct
    41701 gacaatttag attttgaaaa atctttagtt acagtgtcta taaatgatgt tattgtggga
    41761 agtaaaaaat tggataggtc acattctaat aatgataagt tagaattaaa aatacctaaa
    41821 gatatagata ataaaaacta ttatcaagtt aaattgacat ttaatttgag tataaaaaat
    41881 tcgaattgtg ttactagaga gagtaataat ccttgggcat atgtatcaaa taattcttat
    41941 ttggcgttat ctacgaaaga aaatgaaacc ttatcttttg aaaattatcc gtatccattt
    42001 gttagagatg atgaatttaa tgatttaact gtgataatgc cagattattc agggtcacaa
    42061 gctatgacct ggatgtttag attaggtgtt actttaggtg cgaatataaa ttcacataat
    42121 ggaaatataa atgtaattag aggaaaagaa tttagtgaca agtataagga tactaatatt
    42181 gtagtttttg gagtgccaca taataattct gttataaaga tgttaaataa taatttaaat
    42241 ataaagttcg ataaaaatta ctccaatttt atatcaaatg ataagataag ctttattgat
    42301 gattatggaa aaaatatttc tactattcaa ttaataaaat caccatataa taatcaaaaa
    42361 aatatcatgg taattagttc aatgaatgaa aaaaacttat atttaggaat ggattatttg
    42421 ttgaataaaa gtaaagttaa tgatttaaaa ggagatacat tgataattga tgaatacgga
    42481 gaggtagaag atttagctta taatttaaaa tctaagaaag aagtaaaaga ttcaagttgg
    42541 aatatgagta taaataagac aactaaagta tttttaatga tttcttttat tactataatt
    42601 atagtcatga tattatcaat gctatatata aaaaaatata aaagaagata atatgataaa
    42661 tttattattt taaaagaggt atataatttg aggaaatata tgaatgaatt taaattaaaa
    42721 agaagtattt taatctcatt aataatctta atttttatat ttatagttta ctttgtaagt
    42781 attgagttaa aagataggag tctagtaaat aatcaatata aaggtaagat taaatcggcc
    42841 aatttatctg tagattatga aataaatcaa gttatgaagg atatagataa attgggattg
    42901 aatacagtaa atgtacctat aattataaat gtagagtcca ttaattctga tattatgtca
    42961 atagataata atagtaaaga aaaggcaatt aagttaataa aaaaattaaa taaaaaaggt
    43021 atttcaacaa tattagaggc atatccatgg attgaaaatg gaaaattgta tgagactgac
    43081 tggaacccta taaataaaaa aagatttttt tatacttggc aaaatgccat attaaatgaa
    43141 cttataattg atgtagcaaa tccactggat gtaaatgttt taaatattgg ttctaatttt
    43201 gtacatttgg aagaatatca acaaaattgg ggtgaaataa tagattttgt acaatccaaa
    43261 tttgacggtc ttgtaacgta cagaactaat tggtggtata caaaaaaaga tgatttaagt
    43321 agtaagttgt tttatgaaca aaagctgaac aataattttt ttgataagtt agattttata
    43381 tctatagcag catattttga gttaagtaat aaacctgtta atacagtgga tgaattaatt
    43441 tctgccttac actcatctac tgtaaacaat agaggacaaa atataaaaca agaaatatat
    43501 aacctttata aagctcatag aaaacctata ttttttggag aattaggttt ttcaaataga
    43561 gaaagtgcaa gttctcagcc gtggaatcat actccttcaa aagctgtaaa tggcgaagaa
    43621 caagcaaggt gttttgaggc atataagaaa gtttttgaaa atgaagactg gataaatggt
    43681 ttttctgtgt tttgtgtagg taaaatagat gacgaaaaaa atttttaccc atcaaaagag
    43741 agtataaaag ttattaagtc ttggtatgaa taattttgaa agtgtagaat ttatatagat
    43801 taaatagatg attaggagag atataaatga atgacatcaa ggttatgact gtatttggaa
    43861 ctagacctga agctatcaaa gtagcacctt taataaagga acttgaaaaa agagagaata
    43921 taaaaagtat tgtttgcgtt acagctcaac atagagaaat gcttgaccaa gttatagaaa
    43981 cctttaatat aaatgtagac tatgatttgg atataatgga aaaaggacaa agcctgaatg
    44041 atataacatg taagatttta aataaacttc ccttgatttt aaacaaggaa aatccaaata
    44101 taatattggt acatggagat acaaccacaa ctctagctac aagtttgact gcattttata
    44161 ataaaactct tgttggtcat atagaagctg ggcttagaac ctatgataaa tattctcctt
    44221 ttccagagga gctaaataga caacttacag gtattattgc tgatatgcac tttgctccta
    44281 ctaatttggc tagaaaaaac ttgatttctg aaggaaaacc taataataat atatttgtaa
    44341 ctggtaatac tgctattgat gctttaaaga tgacaataaa agaaaactat aatcatccta
    44401 taattgatga gattggtaac gataggatga ttttgttaac ctctcacaga agagaaaatt
    44461 tgggtaaacc tatgaaaaat atattcagag ctataaagcg aatagtagat gactttgaag
    44521 atgtacagat agtatatccc atacatttaa atcctaaaat acgaactata gctgatgaga
    44581 tatttggaaa atttcctgaa aaaattcata ttatagagcc tttagatgta gctgattttc
    44641 ataacttttt aaataaatct tatatgataa tgactgatag tggaggaata caggaagaag
    44701 ctccatcatt aggtaagcca gttcttgtgt tgcgtgataa aacagaaaga acagaaggaa
    44761 ttgaagcaaa gacacttaaa ttagtaggta ctaatgaaga tagaatatat aattcagtga
    44821 gcgatttatt aataaataaa gataactatg ttcagatgag taaagcatct aatccatatg
    44881 gagatggaaa tgcaagcaaa tatatagtgg atataataat taaaaaattt aattgcaaat
    44941 atttaaatta gataaggcct aaaacattaa ctaattgata taagatttat gataatatta
    45001 aggaatacaa tttttaaggg ggagtaatat ggctagaaaa ttaataaaaa atttgggtaa
    45061 aagtaaaagt gtaaagagag tgaaactttt atttaagaag atttttatta ctgtattcat
    45121 agtagcaagt atagttgcta tttttaatat aacgaaatat tttgaggaat tatacaaagt
    45181 aagggattta aaaagtacta aaattgaata ctatatggat gtggctgatg aagcaggaga
    45241 tggaaaggtc caattaagtt ggaaggcctt acttgctata gacatggtaa tacatgatga
    45301 agatttaagt aatataaaaa agaaagacac attggatata ggggaaaagt ttatagtaga
    45361 agataaaaat ggtaaaggcg aaaaggtgta taaggtaaaa aagtttaata aggtattaag
    45421 cgaattgaaa tttgactctt ctcaaaaaag tagagcaaga aaatacatga aagatttaga
    45481 atacacatac cttggaaata aacaattaga tagtagtgat gaaaaaatta aatttataaa
    45541 gaagttagaa gactcagcta taagagaata tattgattat ggaatattgc cctctataac
    45601 aattggacaa gctatattag aatctggttg gggaaattct aaacttacaa aacagagtaa
    45661 taatttattt ggtataaaag cagataaagc atggaaagga aaaagtgtag aaatttcaac
    45721 ttcagagcat tataatgaaa aaattgtagc tagttttagg tcgtataatt cattacaaga
    45781 ttctgtcaaa gaccacagtt tatttttaat taataataaa agatatagaa aacatgggtt
    45841 gtttgaggca aaagattata ttagtcaagc tcaagcatta gaaaatgcag gatatagtac
    45901 agcagaagat aaaaaaggaa atcgtatata tgcagagcta ttaatagatg ttattaggag
    45961 ttataatttg caattgatag ataataaagt tgagacaaaa taattgttaa ctttatatga
    46021 ggagataaca agataagatt tttttctaca aaaagaatag aaaaattgta aaaaaaacta
    46081 aaaaaatgta ttgacttgtt atttaaaagg tgatattatt attactgtac tcgaaagaga
    46141 acaaaa
//
LOCUS       DAMJWC010000027        46101 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMJWC010000027 DAMJWC010000000
VERSION     DAMJWC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46101
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.027"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            100..483
                     /locus_tag="PC503_001734"
     CDS             100..483
                     /locus_tag="PC503_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2527708.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            485..835
                     /locus_tag="PC503_001735"
     CDS             485..835
                     /locus_tag="PC503_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527709.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(936..1394)
                     /locus_tag="PC503_001736"
     CDS             complement(936..1394)
                     /locus_tag="PC503_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527710.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLEEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1439..2227)
                     /locus_tag="PC503_001737"
     CDS             complement(1439..2227)
                     /locus_tag="PC503_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2527711.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQEGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2366..2803)
                     /locus_tag="PC503_001738"
     CDS             complement(2366..2803)
                     /locus_tag="PC503_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HDF2527712.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3625..4134
                     /locus_tag="PC503_001739"
     CDS             3625..4134
                     /locus_tag="PC503_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527713.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4540..5076
                     /locus_tag="PC503_001740"
     CDS             4540..5076
                     /locus_tag="PC503_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2527714.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(5503..6303)
                     /locus_tag="PC503_001741"
     CDS             complement(5503..6303)
                     /locus_tag="PC503_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527715.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6498..8096)
                     /locus_tag="PC503_001742"
     CDS             complement(6498..8096)
                     /locus_tag="PC503_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2527716.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            8424..8600
                     /locus_tag="PC503_001743"
     CDS             8424..8600
                     /locus_tag="PC503_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527717.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            8774..9904
                     /locus_tag="PC503_001744"
     CDS             8774..9904
                     /locus_tag="PC503_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2527718.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            10145..10495
                     /locus_tag="PC503_001745"
     CDS             10145..10495
                     /locus_tag="PC503_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2527719.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10503..10952
                     /locus_tag="PC503_001746"
     CDS             10503..10952
                     /locus_tag="PC503_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF2527720.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            11054..11629
                     /locus_tag="PC503_001747"
     CDS             11054..11629
                     /locus_tag="PC503_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2527721.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11622..13031
                     /locus_tag="PC503_001748"
     CDS             11622..13031
                     /locus_tag="PC503_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF2527722.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            13215..14648
                     /gene="eutA"
                     /locus_tag="PC503_001749"
     CDS             13215..14648
                     /gene="eutA"
                     /locus_tag="PC503_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF2527723.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14666..16030
                     /locus_tag="PC503_001750"
     CDS             14666..16030
                     /locus_tag="PC503_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF2527724.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16043..16924
                     /gene="eutC"
                     /locus_tag="PC503_001751"
     CDS             16043..16924
                     /gene="eutC"
                     /locus_tag="PC503_001751"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF2527725.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            16944..17597
                     /gene="eutL"
                     /locus_tag="PC503_001752"
     CDS             16944..17597
                     /gene="eutL"
                     /locus_tag="PC503_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF2527726.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17608..18309
                     /locus_tag="PC503_001753"
     CDS             17608..18309
                     /locus_tag="PC503_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2527727.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            18312..19781
                     /locus_tag="PC503_001754"
     CDS             18312..19781
                     /locus_tag="PC503_001754"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF2527728.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19877..20164
                     /gene="eutM"
                     /locus_tag="PC503_001755"
     CDS             19877..20164
                     /gene="eutM"
                     /locus_tag="PC503_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDF2527729.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            20291..21052
                     /locus_tag="PC503_001756"
     CDS             20291..21052
                     /locus_tag="PC503_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HDF2527730.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21065..21694
                     /locus_tag="PC503_001757"
     CDS             21065..21694
                     /locus_tag="PC503_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2527731.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21736..22461
                     /locus_tag="PC503_001758"
     CDS             21736..22461
                     /locus_tag="PC503_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF2527732.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKEVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            22474..22746
                     /locus_tag="PC503_001759"
     CDS             22474..22746
                     /locus_tag="PC503_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF2527733.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22739..23290
                     /locus_tag="PC503_001760"
     CDS             22739..23290
                     /locus_tag="PC503_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2527734.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            23302..24393
                     /gene="eutH"
                     /locus_tag="PC503_001761"
     CDS             23302..24393
                     /gene="eutH"
                     /locus_tag="PC503_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2527735.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            24395..24868
                     /locus_tag="PC503_001762"
     CDS             24395..24868
                     /locus_tag="PC503_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF2527736.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(24988..25089)
                     /locus_tag="PC503_001763"
                     /pseudo
     CDS             complement(24988..25089)
                     /locus_tag="PC503_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            25384..25905
                     /locus_tag="PC503_001764"
     CDS             25384..25905
                     /locus_tag="PC503_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2527737.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            26284..27459
                     /locus_tag="PC503_001765"
     CDS             26284..27459
                     /locus_tag="PC503_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2527738.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27494..29032
                     /locus_tag="PC503_001766"
     CDS             27494..29032
                     /locus_tag="PC503_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2527739.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29064..30266
                     /locus_tag="PC503_001767"
     CDS             29064..30266
                     /locus_tag="PC503_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2527740.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQKKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30433..31032)
                     /locus_tag="PC503_001768"
     CDS             complement(30433..31032)
                     /locus_tag="PC503_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2527741.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            31202..32560
                     /locus_tag="PC503_001769"
     CDS             31202..32560
                     /locus_tag="PC503_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527742.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32553..33185
                     /locus_tag="PC503_001770"
     CDS             32553..33185
                     /locus_tag="PC503_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2527743.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33514..34671
                     /locus_tag="PC503_001771"
     CDS             33514..34671
                     /locus_tag="PC503_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527744.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(34818..35453)
                     /gene="lexA"
                     /locus_tag="PC503_001772"
     CDS             complement(34818..35453)
                     /gene="lexA"
                     /locus_tag="PC503_001772"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF2527745.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35557..36684)
                     /locus_tag="PC503_001773"
     CDS             complement(35557..36684)
                     /locus_tag="PC503_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2527746.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(36995..37840)
                     /locus_tag="PC503_001774"
     CDS             complement(36995..37840)
                     /locus_tag="PC503_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527747.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37870..38241)
                     /locus_tag="PC503_001775"
     CDS             complement(37870..38241)
                     /locus_tag="PC503_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2527748.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(38394..38654)
                     /locus_tag="PC503_001776"
     CDS             complement(38394..38654)
                     /locus_tag="PC503_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF2527749.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38843..39787)
                     /locus_tag="PC503_001777"
     CDS             complement(38843..39787)
                     /locus_tag="PC503_001777"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF2527750.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39808..40662)
                     /locus_tag="PC503_001778"
     CDS             complement(39808..40662)
                     /locus_tag="PC503_001778"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF2527751.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(40677..42038)
                     /gene="accC"
                     /locus_tag="PC503_001779"
     CDS             complement(40677..42038)
                     /gene="accC"
                     /locus_tag="PC503_001779"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF2527752.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42054..42506)
                     /gene="accB"
                     /locus_tag="PC503_001780"
     CDS             complement(42054..42506)
                     /gene="accB"
                     /locus_tag="PC503_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF2527753.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42776..43222)
                     /locus_tag="PC503_001781"
     CDS             complement(42776..43222)
                     /locus_tag="PC503_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527754.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43497..43775
                     /locus_tag="PC503_001782"
     CDS             43497..43775
                     /locus_tag="PC503_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527755.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43904..44650)
                     /locus_tag="PC503_001783"
     CDS             complement(43904..44650)
                     /locus_tag="PC503_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527756.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGKAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44779..45423)
                     /gene="trmB"
                     /locus_tag="PC503_001784"
     CDS             complement(44779..45423)
                     /gene="trmB"
                     /locus_tag="PC503_001784"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF2527757.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45561..45881)
                     /locus_tag="PC503_001785"
     CDS             complement(45561..45881)
                     /locus_tag="PC503_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF2527758.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        17402 a         6143 c         7042 g        15514 t
ORIGIN      
        1 aatttttatt gatttttaaa aatttagtta gaaactatat cattatggta aaaaatgtat
       61 tataatgttt agaaatatta taataaggag cgattaaaca tgaatctatc gaagaaaata
      121 gaagataaaa gaaaagctaa acagagagct gaaaaagtta agaaagctaa aattgctaca
      181 gctggtgtgg tattaggagc tgttactggt gcagtgagtg gagtactttt ggctcctaaa
      241 tctggaaaag aaacaagaga ggatataaaa gatgcttcac aacaaattgc tgaaaagata
      301 aatatgaaaa ctgtagatgt aaaaggcaaa gtatctgaga agctagagga taaaaaagga
      361 aactttatag aatcaaagaa aaaaataaaa aaatatatag ataacaaaaa gagtgttgaa
      421 aattctagtg aggaagataa aataatagat atagttgaac cagttagtgt tactgaggaa
      481 taatatggac aatacaataa cgattaacat aagtataata tatgtattat tagctatact
      541 tgcttgtatt gctttagttt atttaattat tgtacttgtt aaactacata agattttaaa
      601 taatgttgga actatgttaa atgaaaatac tcaaaatata aatacaactt taaataatct
      661 tcctaatgtt gtagaaactt ttggagaagt aggagaaaat atgaaagatg taacagaagt
      721 agttactgaa gttacagcag attttcttgt tactaaagac agtgtcaaat caaatatgga
      781 tgttatagtt gatatattga ctataattaa aaacattttt ctagataaaa aataataagt
      841 ttaattaaaa taagcctata agatataatt taaacgacct taaaatagca tttataaggt
      901 cgttttttat tagcttgatt tgacactatg tgtttttaat aattggtaat attcctcttt
      961 atcatttgaa catatatatc tatgcttgtt gtttcaatta catccataag aacatcttta
     1021 cattcaagct caaaatcttc cattccttct aaatattcat catcttcatc aaaaaagata
     1081 taagaattat atagccattc ttcaaatttt tcttcaagta tatcccaata cgaactccaa
     1141 aataatccac aacctgatat ataagatgct ctactttgat ttatataaac ctcctctaga
     1201 agcttttgta atctactgct ataaagaaaa tctgctcttc cactgcttga tattaattca
     1261 tttaaatctt ctattgacat taattcaact ttaccacttt tatcataagg agtataattt
     1321 tcatcaaccc atttatgtgg tttgttttct ctgcatactg ttgctatcaa ctctacaact
     1381 tttgttctta tcattttttt atcctaactt atttattttt tataaaataa tcatgatttt
     1441 ataatttatc tatttcttgt aatgctaatt taacagtttc atatctatca gcaccattta
     1501 ttactacatc accttttaca agtttattag cttctccacc tacaacataa acctttttac
     1561 ctaaaccttg cttataacta gacgcttcaa ttattaaaga atctttcaat tgccaatgta
     1621 aaatctgagc agccacttta tcagcatcac ctgtataaac gattacattt tcatacactt
     1681 tattttcccc tccctcttga gaatttgata tagatttgtt tagtatacct tctgctatca
     1741 atttagcaac tttatcttta ttattaacat aataatctgt atctgcttta ctatctacaa
     1801 aacatacttc tattaatatt gctggtgcaa tagtatgatt aagccaataa agacctctaa
     1861 catcagactt tgcgccccta tctttgaata ctgtagctaa cctagtattc actctttctg
     1921 cataggtttt gccattatta gtcttatata ttgtttctgt ccctactgga gttgaagttg
     1981 tggcatttga attaaaatga atctgaacag ccaaatcagt ttcctgttta tttgctatag
     2041 cacattggtc tgctaaatga ttacttgatt catcaactct tcctgtataa acagtagctc
     2101 cacctatttt aagccattta acaattaagt cattcagtat tcttgtttct ttgctttcgt
     2161 ttatataccc aacagctcct gtaccttttc caattaaagt gtgccctggt attattacta
     2221 ctttcaaact aacatctcct ttacaattaa atttaacttc tatttaatat atgcataacc
     2281 tagaattttg tttcttttta tatcttatac ttttattata acccattttg taaaaatata
     2341 gaatattaag taaataatgt taaaattata attttgtata taagacatta cttgattgca
     2401 ataattttat agcatattca tctattctat atccagttct ataatatata tgtttaattc
     2461 cagcttgaat tatagcctta gtacaattta agcaaggaaa gtgagttaca taaatagagc
     2521 aatttttaac tgaaatacct tcttttgcac aataataaag ggcattttgt tcagcgtgaa
     2581 tggttctaat acaatgtcca tctctcattt catgaccaac ttcactacaa tgcttatctc
     2641 cagaaatact accattatat ccagtagaca ctattctgtt ttctgaattg acaattatag
     2701 ctcctacata agctctatca caagttcctc tttcagctac tgtttcgcac agtctcataa
     2761 aatattcttg ccatgagcat ctattttcaa gttttttatt caaattatat acctccaaaa
     2821 cttatatcta atatataaga tttatacctt aaaaataata ttaaaaacaa atttatacga
     2881 taaataaaat ttattaatac tgtttttagt ctaaattatt tcattttaaa ttaaagttac
     2941 aaggaatcta aaattatata tatctttctt cgtaatatta atgttacaat ataaaaaact
     3001 gtctcaataa aatagagaca gttttacagt caaagtttat aatacaagtt catatttttc
     3061 tttaaattct tttacagctt cgggccatgc cttttgttct gtaatacctt tttctttagc
     3121 tattttaatt gcaatctctc ttatcattgc agcgccttct aatattccca tttttaatct
     3181 cccttcaaat atctttttgt atagaatata aatagtgcta agatttatta catgctgcat
     3241 atacaatatc tatacaacac ataacttgta aattcctttt attttcatac gtctttaacc
     3301 gacatataat tatattcaat aagttttaaa attatgaact caattataat tatttttatt
     3361 tttttagaat ctaaacacta aaaattgtag gtaaatttgt cttatgcctt tataaatatt
     3421 tctacagttt taattactgg acatatctat ttttattata aaaagcgatt aaaaatcgag
     3481 aatatccgca taaaaactgt atataagcaa aacggttaaa ggaaaaagaa gaaatttact
     3541 tgaatgttaa aatgcgttgc ttgaagcaat gggcagtttt gcctataata tcggtaacaa
     3601 ctgaaagaaa ggtggttagc cctaatgtta agcgaaaaca ttaaaacaat caggaagtca
     3661 aaaggacttt cacaacaaga acttgctata aaactgaatg tagtgcgaca aacaatatct
     3721 aaatgggaac aaggactgtc agttcccgat tctgatatgt tgatttccat atcagaggtg
     3781 cttgaaacgc ccgtaagtac tttacttgga gaaactattg ttgagtcgga agttgataac
     3841 ttaaaagtga tttctgaaaa attagagatt ataaacttgc aacttgcaca aagaaaaaac
     3901 atgagaagaa aaatgtttca ttggttattt attttattat gtgcagtcat attaatagtt
     3961 tttgtggtct tagggggact aaatagtcct tacttggatt ggaattatac cgaccctgaa
     4021 accgctgttt ttggagtagc ttttcatgct tttgagtggc tatttgtcag attagtaccg
     4081 attgtcctta taggagcaat tattggaatc tttttgacac gtaagaaaat atgaagtaac
     4141 tctgcttttt ataatacagc aagcgttcct taaaagcgtc attctacatg gcaatcgagg
     4201 acgactatgt aaggaagaac ctttttgatt tccaactaag cgaagttatt gaggacgaca
     4261 gtaagaccaa aaccgcatta agtaaagtac aggaagcaag actgctggac ttatactctc
     4321 atgcgtcaga tgcaggaaat gcgaggtctg gtagcatgat ttacaacgat ttgtacaacg
     4381 actgctagta gaaataatat ggagataagt attatctaca aagtcagaaa agaaatgact
     4441 tgataattta ctcatgttat aattattgat gtgaaattaa taaatcgaaa ttcctttttt
     4501 ggatttaata atactgagta aggaaaaagt gaattacttt tgcaaggagg tgttaatatc
     4561 aggcaagtaa agtcttttgt ttttccagtt atatccttaa tattcttaga ccaaattagc
     4621 aaagttctta taggattatt cttaatggac tttgaaattg atataattgg gaaattttta
     4681 agattcaatc ctgttcaaaa tacaaatctc tcttatgggg gaaactttat tggtattcta
     4741 tctaatttat gggtattggt attgtttaac attttagtta tattagttat tatatctgga
     4801 tatgcttttt ataaatcaaa aaatgaacaa acaagctatt cagtaaaagt aattatgtct
     4861 tgtggacttg ctggtacaat atgtagcttg atagataaat tattttgggg aggaagttta
     4921 gattttttgc agataccaag cttttttatt ttcgacttaa aagactgcta ccttactgtt
     4981 gcagaaataa tatttgttgt cataggaatt ttgcataata gagaaatatc aatgaaagaa
     5041 tacatatatt tttgctatcg tcagtttaaa aaataaattt agaagataaa tttaagtttc
     5101 aaggtaaact tatttaatca cagcaaatag ttggcttact taagcttttg ggctaaactg
     5161 tgagcactaa ttaagtctct gatatctaac aaacggagca caaaaataaa aattaaatat
     5221 aaagcacagt taattttgat taaaaagttg actgtctttt cttttgtaga aatttaagca
     5281 taggtaataa agaaatgact gcatttaagc attatgtata taattggagg caataaaaag
     5341 ccagcaaagc ccataaaata gagctgtgct agcaacatga tgaattataa gaagataatc
     5401 aaaaacttac gctttatttt aatttaaaaa aatgattact gtaaagaaat cattttttat
     5461 tataatcact gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat
     5521 tttttctata atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac
     5581 tcccatcatt actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat
     5641 tccatatctt gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt
     5701 aattttagtt aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat
     5761 ttgagattta gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat
     5821 aaaataatta taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac
     5881 gattccttct attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg
     5941 aagagcattt aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca
     6001 aagagcaatt gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc
     6061 atatacagat attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa
     6121 attgtaaata tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa
     6181 aagttcccag attacaataa aaccaattaa aattaatagc tggtagaata atacatttct
     6241 tttttctctt tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct
     6301 catgtgtatc tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac
     6361 gtgttttgag aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta
     6421 tggtagctgg tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta
     6481 tagctaaaaa agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata
     6541 taaacaatat taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat
     6601 aataacaatc tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa
     6661 ttactaacaa taatatcaat attaatactg tcactactaa tattgatgtt actagattcc
     6721 aaagtattaa tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa
     6781 actatataat cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta
     6841 ataagtcttt ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata
     6901 ttaaaaacat tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct
     6961 ttacaattct taattttatc tataactaaa ctttcaacta atggaccatt aagattttta
     7021 cagttgcaac tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa
     7081 tccttgtcag tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat
     7141 tttataagac cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga
     7201 tttttatcta attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt
     7261 tttgcaattg ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt
     7321 ctatctggag tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca
     7381 ttagctttta catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg
     7441 ccaccacgag gaccccttat tccattatta tagacatatt tatataactt agataaggac
     7501 ctaagttcta aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact
     7561 tgaagcttat acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg
     7621 ttgaatccat gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata
     7681 ttgtctttta tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata
     7741 aacatcatag ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat
     7801 gatatgctta gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat
     7861 atcctatcta atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc
     7921 attttcttaa attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc
     7981 aaaaaatctt ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct
     8041 atagaatcac cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt
     8101 aaaaccccct ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa
     8161 acttattaga atgaatttat taattaggta aatttatata attctacttt ttataatata
     8221 tgactattta ttttatttct ttactattca agttctaaat caataataaa ttttgatatt
     8281 taattgtatc aggacaaatc tctaatttca tagattatta atataaaatc ataggttagt
     8341 gtgaaaaagt tgaaatttaa atattttaaa agataatttt tttgaactaa taggtataac
     8401 aaaaatttat agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata
     8461 aagctaaact taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta
     8521 aaaaatatcc taaagaagct ttaaatgaag catttagtac tttagaaaaa gaattaaata
     8581 taagtaaagc taatacataa gctttgatta ttgattttat atactattgg ttttatacgc
     8641 tatgacttga cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt
     8701 aaaagagcaa tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa
     8761 ggaggatagg actttgaata actttgagat taaaactaga ataaaatttg gagaaggctc
     8821 actaaaagct ttgcaagaat taaaaaacaa aaatgtacta ataataacag acccttttat
     8881 ggtgaaatca aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt
     8941 ttttgaagaa atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt
     9001 taaatctata aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc
     9061 aaaatctata atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc
     9121 aataccaaca acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag
     9181 tcaaaaaaaa tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact
     9241 agacccagaa cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt
     9301 attgacacat gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact
     9361 agctgaaaaa gctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa
     9421 tgacatagaa gctagagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa
     9481 ccaagcatca cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat
     9541 accacatgga agaacaaact ctatattact tcctcatgta atagaatata attcatcaat
     9601 agtaggatat actaacacaa cttactctgc tacagctaaa aaatatgcac aaatagcaga
     9661 attagtagga cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat
     9721 aaagaaacta caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt
     9781 agaagatata actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac
     9841 attaactaat cctaaggtac caactgaaga tgatataata aacatattaa agaacattaa
     9901 ataactacat tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa
     9961 aatataaatt atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg
    10021 cgtgatactt tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga
    10081 gctcctttta ttttaatcaa atagcttttt aataaactat attcaaagaa agcagggaat
    10141 aaatttgact gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt
    10201 tacattagca catatcatag ctaaccctaa tgaagatata tataagaagt taggattagt
    10261 acttgataaa aaagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat
    10321 agcagcagat gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag
    10381 tggttcagta gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt
    10441 agaagtctta ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata
    10501 caatgaagaa tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa
    10561 aactagacca gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg
    10621 caatagacac tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa
    10681 catcagcaga tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata
    10741 tagcaccagg ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa
    10801 ataaagctac tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa
    10861 gtcaaatctt taaaatagac acagttgata atattggact tgaaaaatta tttaaatatc
    10921 tagaaaaata taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat
    10981 tattaaagta tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa
    11041 gcgaggtagg aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat
    11101 ggatacaaaa gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg
    11161 atttgaagct gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga
    11221 gatgccaata cttgatggta taaaggcagg caaaataata tgtaaagaaa atatagctgg
    11281 tggagtactt ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat
    11341 aggtgcttat ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga
    11401 aatgtgttta aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa
    11461 ttctaaattg aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt
    11521 taagatttct gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac
    11581 tacaatgatg gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa
    11641 aaatatcaac tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat
    11701 caaaatcctt agatttaatg gcttcttttt atgaagctga tgtttttata gatgtactaa
    11761 gtaaatttga tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt
    11821 actgtgaaaa tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt
    11881 gcttaaaaac aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg
    11941 tcaaacaaaa tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg
    12001 aaaaagatat aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata
    12061 aaaatttaca tcagtttata aaacttattg gaaataatga ctttttagtt gataatttaa
    12121 attcagccat attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa
    12181 ctgagatata caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt
    12241 tagatataga aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa
    12301 atgaagtttc aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg
    12361 aatttaaggt ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat
    12421 tagttttgaa aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata
    12481 cagtaatatc tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt
    12541 gtttagataa cataataaat agggtatttg caatactttc gactcattat ttactatcta
    12601 aagaagttga taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc
    12661 aaggtggcta tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa
    12721 ttagtggaga aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt
    12781 atgaccatgc attttcggat agagaacatg gtactataca aatattaata aataaagata
    12841 acgactatag aaatattgct attatagatg atggaattgg atttgatagt aataatataa
    12901 ataaaaatag cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa
    12961 atatagagag aaaaagtagt gagaatggta cagaagtatt aattactata cctacacaaa
    13021 ttaatattta aataataact catctacaaa gtagtagttt taattgagca aagaggctta
    13081 aggttattaa tagattaagt taattgaatg tatttataaa aattataagt atatattcaa
    13141 tttaacaggt atttattata actttaagcc tctttgcttg tttaagacat acttaaattt
    13201 taggaggtga gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta
    13261 ctactcagtt aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac
    13321 ctagaataag tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc
    13381 ttatttcaaa taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata
    13441 aaaaagcaaa tatatctaaa gaagatatac atacaggagc agtaataata actggtgaaa
    13501 cagctagaaa agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact
    13561 tcgttgttgc aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag
    13621 ctcatattta ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa
    13681 ctagtaacat agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag
    13741 gtggaaggct tgtaaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa
    13801 tagataaaat cataaaagat aataatttaa atcttcaagt aggcacaatg gctactgtag
    13861 aaaatacaaa gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggattaa
    13921 agaaacagac acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa
    13981 atattaaaaa tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa
    14041 taaaagatta ttttgaatat ggtgacttgg gaattttact tgggcaagca ataaaaaatt
    14101 gtgaatacct taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg
    14161 ttggagcagg ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa
    14221 agtttccact taagaacttg ccagttttaa aattatcaat tgatgaagaa acaggcactt
    14281 caaaacaaat cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt
    14341 tacagaaagt tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag
    14401 agtatgctaa agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta
    14461 tagtaattgt tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa
    14521 attatgaaaa agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg
    14581 acattggaaa acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt
    14641 ttaattaata gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta
    14701 tcagtttaaa ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa
    14761 attagcaggt cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc
    14821 acacataaaa ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt
    14881 aacaagaata atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac
    14941 agtctctgaa cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag
    15001 aatatcaaga ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat
    15061 ggacttagtt tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg
    15121 agaacaagga acattatcag caagacttca acctaatcat ccaacagacg acccagatgg
    15181 aatacttgca tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt
    15241 aaatccagtt gatgactctg ttgagagtgt tactaaagta ttaaaaagat ttgaagaagt
    15301 aaaacaaaaa tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat
    15361 ggaagcaata agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga
    15421 aaaaggaaat gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc
    15481 cttaaaacac ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc
    15541 agaattatct tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta
    15601 tggatttgct aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc
    15661 tgagtactta tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg
    15721 taaactacat ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga
    15781 ccaaaatgat atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat
    15841 gggaatacct catggagatg atgttatgct taactatcaa acaacaggat accatgaaac
    15901 agcatcactt agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga
    15961 aaagatggga ttctctaaag atggtaagtt aacagagttg gcgggagacg catctgtatt
    16021 attaggatag gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt
    16081 agttggacaa atggttggag aattagatac taatgttgtg tctgagactg ttaaaaaggc
    16141 aactgaagtt gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag
    16201 aaagcaatta ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa
    16261 aacacctgca agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt
    16321 aagatttaga gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga
    16381 atttataaaa gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata
    16441 cttaacaaga ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc
    16501 taaatttggt acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc
    16561 aatagaggca aatttaaaag actgtgtgcc agctataaaa caggggctaa aaatgtatgg
    16621 tatagattca agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt
    16681 aggtgaagaa ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt
    16741 tactgctgaa tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc
    16801 aaaaagaaca gttatatcaa atattcacaa aggtggaaca actgcagttg aagcaggtgc
    16861 tcatatagct gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa
    16921 ataaagtcga gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa
    16981 ttaaaataat ttcaaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc
    17041 acaaaagctt aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg
    17101 aagcaactaa agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg
    17161 caaatgcttc aacaaaactt gctggtgaag tattaggaat aatagcaggt ccaagcccag
    17221 cagaagtaag aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta
    17281 taagtgcaaa tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta
    17341 catacctttc agaggtagca ggaataagag aaggtgaagc attagcttat ttagtagcac
    17401 caccacttga agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt
    17461 gtgaattatt tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc
    17521 aatcggcttg taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca
    17581 atccaacagg attttaagga tagttagatg gatgctatag gcttaataga agtaatagga
    17641 tatgttgctg caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta
    17701 agagttgata aggttggagc aggtattgtt actttaacaa tatgtggaga tgtcggtgct
    17761 gtaaaagctg ctttagaagc aggtgaaata gcagcttcca gagttggtac attaagaaca
    17821 tcacatatta taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa
    17881 cctaaagtct gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata
    17941 gctgataatg tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa
    18001 aacagtggag atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa
    18061 acagttgatg atagtttaac agaagctaat gaggaaaaaa tagaaaacac taatgataaa
    18121 gaagtattgg aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag
    18181 aacagtgtaa aaaaacttaa agctatggct aagaaattag attcttcaat aacttataaa
    18241 gacttaaatg ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagtagaagg
    18301 gatagatagt tatgacactt ttagataaag atttagtatc tatacaagaa gtaagaactc
    18361 ttgtaagaag atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag
    18421 ataaaatagt aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa
    18481 tggcaaatga agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg
    18541 catctatggg agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag
    18601 ataaagaagc caatacgata gatatagcta caccagttgg agttgttgca ggtcttatac
    18661 cttcaacaaa cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa
    18721 atactatagt tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata
    18781 taataagtga tgctgctata aaggctggag ctccagagga ttcaatatta tgtataacta
    18841 atccaagtat agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag
    18901 caactggagg agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag
    18961 ttggaccagg aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca
    19021 aaagaataat agattctaaa acttttgata atggtgttat atgtgcatca gaacaatcta
    19081 tagtaataga aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat
    19141 atgttttaaa tgaggaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta
    19201 ctatgaatcc acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa
    19261 caaatgtacc taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg
    19321 tagcctattc aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa gaaaatgtag
    19381 aagctattat gaacagatgc agagaaatat tgttaaatga aggtgcaggt catacattct
    19441 caatgcatgt aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa
    19501 gaatacttgt gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac
    19561 cagcactaac acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac
    19621 cacttgattt aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg
    19681 gaagagataa atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa
    19741 taaatcttct tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac
    19801 ttatggctat cgctataaat ttctaaaaat ataaactata aaaaactata aaattaaatt
    19861 tttggaggat aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt
    19921 agtaggagca atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg
    19981 aaaagagcaa gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt
    20041 taaagctgct acagatgcag gagctgccgc tgccgagaga gttggagaac taatatcagt
    20101 tcatgttata ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga
    20161 gtaatataag aataattata aaatttaaat tttgattgaa aaagaggcta tctcaaaaat
    20221 gagtcttact aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag
    20281 atgtgataaa atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa
    20341 aaataatata actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc
    20401 ttatttagct gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa
    20461 tgaacctaaa gaagttgtaa aagaagtagt taaagagaaa aaatatagat atactactgt
    20521 atttggcgct aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt
    20581 agtttttaaa gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga
    20641 aatactaaag gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt
    20701 gcaagaagta ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct
    20761 aggggacttt aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc
    20821 taaaaaatac tttggtatag gacatgagtt cccaagttat gaaatgggag aagtagtagt
    20881 agctataaat agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt
    20941 taagggtgag tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc
    21001 gtcagtattt tggataatga tatataaggt tagaactaat aagtataagt agttggagga
    21061 cataatggag aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga
    21121 agcatttata gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga
    21181 taaattattt ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca
    21241 atatgcatgt aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt
    21301 tgtacttgga ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac
    21361 tcttggacta aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa
    21421 aatatcaaca caatatggtg aagttgaact tgataagggg ttaatggttg ctaaaagaca
    21481 tatacacatg actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga
    21541 agctaaggtg atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga
    21601 cagttttaaa acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa
    21661 aggaactgtt gctaaaataa taaagaaagc gtaaatttaa cctactatat aaattacctc
    21721 tagggaggat ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat
    21781 aaaaaaataa atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt
    21841 gaacaagata acaataaatt taacttatta aaagatgaat ttgaaatagt agaatttgat
    21901 aaaagtataa gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg
    21961 aatatagcac ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg
    22021 aagggcaaag aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact
    22081 gcaccaaaag cattatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt
    22141 gtagaaatta taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa
    22201 ctagaaagta ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatgtttta
    22261 aatttaacca gtgtagaaag tgtaaaaata gataatgaat ttagtttaga tttaaggaat
    22321 aaaaaactta tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata
    22381 ttagttaata aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat
    22441 ctcaaactaa agaaagtgta aggaggtaat tttatggata taggaaaagt tgtaggtaat
    22501 gtttgggcta caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt
    22561 ttaaaaacta aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca
    22621 ggaaatggag acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa
    22681 tctcatgttc cggtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat
    22741 gaataaaagt ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa
    22801 tgaaatgata aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa
    22861 atttctaata atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat
    22921 aaaacttgga gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat
    22981 attagatgga tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt
    23041 tgaaagtagt aaagtatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga
    23101 cttagtatta gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatatagt
    23161 agcaggagat ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga
    23221 aaaagaagta atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct
    23281 aataaaataa tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc
    23341 ttcatggtac ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa
    23401 tttgaagaag gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt
    23461 ttagcaccag ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt
    23521 ggagctgacc cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcacca
    23581 cttgcacttg aacttgcgaa agaccctaat gctgggttat ttggtggatt aatagtaggg
    23641 gctatgatgg gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa
    23701 gaagaccaaa aattcttagc aacaggaata cttgcaggta taataacaat acctattgga
    23761 gcattcgttg gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg
    23821 ccaataataa tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg
    23881 ataaaaggat tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct
    23941 gctgccatag ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt
    24001 gaaggtatag aaatagttgg agatatagca atagttttag caggagcatt cccattagtg
    24061 tttgttataa caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg
    24121 aatgatgtat cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt
    24181 atgatgaaag atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca
    24241 gcattcgtat ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca
    24301 ccaatgatag ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc
    24361 gcaaataaga cactaaagaa ggagaatgta taagatggat atatcaaata tagataaaaa
    24421 tttaattgaa acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac
    24481 agtagatttt gttagaaata aagacattag tggaataact tctataaagt taccaactgt
    24541 aaaagttagt gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa
    24601 agatttattt acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga
    24661 aacaactttt gattggactc taaactatga tgaaatagat tatgtaatag atggaacttt
    24721 agatataata atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tatttatacc
    24781 aaaaggaagt aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata
    24841 tccggcagat tgggcatctc aaaattaata aaaatcaagt taagttaata ataatcaaat
    24901 aaataattta aaatacaaac tcttaaataa gcacacatat ttaaaaaagc tatgaattaa
    24961 aattcatagc tttttttata aagaatgtta tattttagac gtattttttc tatatttact
    25021 gggagacata ttatattttt tattaaataa tctaataaaa tgctctacat ttggataacc
    25081 aatactattt tactgataat cttttcctta tcactaatct tacattttaa aatattattt
    25141 ttactcgtaa tattatcata agaatttgtt tcttatttaa aactaattag aattataaag
    25201 tttattgcca tgttattaat aaaataaatc cagttaaatc gagtgctagt taaagtaata
    25261 agaaactttt acaatggttt cctttatcga ttgaaataaa agttaatatg gtataatatc
    25321 taaagagaga atcttatcaa ttagaatatg catagaaaca agtggcttaa aaggagacgt
    25381 tatatggaag agatagtaaa gaaggaacaa gcaagtatga atgatatttt tttgtatctt
    25441 aaagctaaat caaactcatt atataaattt gtaatattat ataatgagtt tatcaataaa
    25501 cctaaagatt atggaactgg ggaacttata aacatggttg aagtacatat gctaacagcg
    25561 attgaagaaa atccaggaat aagtccaact cagttagcta aaatatggaa cagaactaaa
    25621 ggtgcaatat ctcaaactat atctaaattg gagaaaaagg gttatataac taaagaaaag
    25681 aaagaaggaa atgcaaaaac tatattacta tatccaacca catcaggagt agagttaagt
    25741 aaggcacata aactatatga caccatagat gttacaagaa catttgaata cttaatcaag
    25801 gagtgtacat tagaggagat agatagtttt tataaagtaa ttgatttgtt tattaattta
    25861 ttagaagaat ctccgcagga aaataatgat tctgaaaaag tgtagctgag attgaagttg
    25921 aataaagaga aatagatatt atagaagtag tacttaagta cacattatat aaaaatataa
    25981 taggtatagg attaaaaagt ttagtggttt aaagtttaac cactaaactt ttttaatgtc
    26041 tataatctac tattatttaa tttactaaaa ataaaaaaac tcattatatt aagataaaaa
    26101 tagaaaaata actagaaaaa tactataata tatcagctta atacagaaaa aagttaaaaa
    26161 atttgagaaa aataaaaatg aaaacgtttt atattgacat agagaaaaag tagtgatacc
    26221 atttaaatat agtttagtag ctaaactata tttaaattat aataactatt ttagggggat
    26281 gttatgaatt taaaacaatt aagtgaaaaa tacgaagaat atgtaattca aatgagaaga
    26341 gaatttcata agtatccaga attatctttt aaagaaataa gaacaaccca aagaataagg
    26401 gaagaattac aaaaaatagg ggtccctttt gtatctattg aaccaaatat cgtaatagct
    26461 actatacaag gcaaaaatga aggtaagaca attgcaatta gaggagatat agatgcgctt
    26521 ccaatgcaag aagattcaga tgttgaatac aaatcagaat atgatggaat aatgcattct
    26581 tgtggacatg atgctcatgg agctatgtta ctaggacttg cacatatgct aaatgatata
    26641 agaaaagatt taaaaggtag agtattatta gtttttcaag cagctgaaga agttggtggt
    26701 ggacacaagg agataataca gtactttaag gaaaatggag gaccagatag attaatagct
    26761 actcatgttt ggtccgatat tgaagctggt aaaatttctg ttgaaccagg acctcgtatg
    26821 gctggtgggt ctggttggag aatagacata acaggtagag gaggtcatgg ttctagacca
    26881 gatcaaagca tagatcctat aaagccagct tgtgatatag ttttaaaagt atcttctata
    26941 ccagttaatc atataagtgt actagaacaa tgtgttgtac atgcatgtgc aatacatgga
    27001 ggaactacaa taggaaatgt tattccaaac aatgcagagg taataggtgg atatagatat
    27061 tttactgaag aatcaggcaa aaaagtgttt gacattataa agcaaatgag taatggtgtt
    27121 ggacaagttt atggagtgga tgtgaaggtt actcatactg gaggcatagg acctgttatc
    27181 aatgatgaag aagcagttaa gatggctaaa gaaatagttt ctaatataga tggattggag
    27241 ttagattctt atgagccaat atgtgcatca gattgttatg gtgaaatatt aaaagagtat
    27301 tctggctttt attgttatct aggggtaggt aacaaagaaa aaggaataat atatgcacaa
    27361 caccatccta agtacaatat agatgaagat acattaaagt taggttgcga atttatggct
    27421 aaatatgcag ttgaattttt aaataaaaat aataactaaa ataaatcgaa ttttataaat
    27481 gggggggatg aaaatgcaag gtgcattaaa ggaaaataag aaaaaaagtg gtggaggatt
    27541 tttaggatgg attgaaaaag ttgggaataa aatgccacat cctctagcat tatttacata
    27601 tattacattg atagtagtag cattatctgc aatagcaagc tttttaggtt tttcagcaac
    27661 aagtcctgct acaggaaagt taataaaagt tatgaactta ataagtgcaa aaggtttagt
    27721 actatttatg caagagtttg ttaagaactt ccaaaacttc cctgtgcttg gagtagtttt
    27781 agttatggca gttgccacag gagtttgtga aaagacagga tttttttcaa ctgccataaa
    27841 aatgagttta tcaaaagtta aggggaatgc ggttgtattt ataatagctt ttataggagt
    27901 atttgctaat caagctggtg atgctgcttt tgtattagta ccaactcttg caggagcaat
    27961 attttatgga ttaaatagaa atccattagc tggtatattc tgtggatttg catcagttgg
    28021 tggtggattt gcaacagctg taattcctgg gggatgggac gttacgctaa cgccaataac
    28081 tgtatcagct gctcaaacta ttcaacctgc atttgatatg acattattag ctagttatta
    28141 tgcactattt gtatctgcgt ttatagtagc tacagtatca acaatagtaa cggttaaatt
    28201 tatagaacct aaattaggta agtatactgg taaaccagaa ggtatagatg ataatcaagg
    28261 ttttgaggtc acaaaagaac aagcaaaagc agcaaagtta gcaggtttta cagttttagc
    28321 ttatgtagcg ttattaattg ctttgtgtat accagctaat agttttttaa gaagtccaga
    28381 aggttcttta atatttggag caccacttat gtcttgctta cagtttttta tagtaatact
    28441 attcttcttg ccagggattg tgtatggaat gagggttggt aaaatcaaga ctgtaaaaga
    28501 cttaaatgat atattatgtc aatcaatggc agcaatggca ccgtttatcg tacttgcaat
    28561 agttataggt caattcttaa cgctattctc agtgtctaat ttagcacagg tactagctat
    28621 aaaaggtgga gcattactca actcattgcc actaccacca caagctataa tactgctatt
    28681 cttagtacta gtagcgttta taaatatatt tgttataagc ggaagtacaa aatggatgat
    28741 atttggacca gtatttgttc caatgttaat gcaattaaac atacatccag catttactca
    28801 gtttgtatat agattaggag attctgtaac caatcattta tcaccattaa atgcattctt
    28861 tataatactt ttagcaacag tccaaaaata cgataaaaat gcaggtatgg gaactatatt
    28921 ctcagctatg ataccttaca ctataggtta ctttgtagta cttgcagttt tagtagtagt
    28981 ttggatgaca ataggtatac cagtaggaat aggtggacaa gtttggttat aaaacatatt
    29041 taataatttt gggaggaaag aaaatggaaa caactgaaat aagatacaat tttgatgaag
    29101 taatagatag aagtggaaca aactgtctta aatatgatct taagagtcaa tttatgccag
    29161 aatctccaga agatgcacta ccactatggg tagcagatat ggattttgca tgtgcccctg
    29221 agataattaa tgcaatgcat gaaagaatag acagaaaaat atttggatat agctctcaac
    29281 aaactgatga ttattatgaa gctgtatgtg gatggtttaa gagaagattt gattggaaaa
    29341 tagaaaaaga gaatatattc tttagcccag gggttgtgcc tgcgttagga tttttcacac
    29401 aaatattaac acaaaagggt gatggtatca taatagaaaa gcctgtatac tatccttttg
    29461 aagataaaat aactaataat gaaagaaaag tagttaatag tcctttaaag tttgaagatg
    29521 gtcattattc tatggattat gatggatttg aagaattagc taaagatgaa aataataagg
    29581 tgtttatatt atgtagtcct cataatccag ttggtagagt atggaaaaaa gaagagctta
    29641 gaaaaatagt agacatatgt aagaaatatg atttgtggat aatatctgat gaaatacatt
    29701 gtgatattat tcgtaaaggt gaaaagcata taccattaga agtagcatgt cctgattata
    29761 aagatagaat aataacttgt acagctccaa gtaagagttt taacttagct ggtatgcaat
    29821 tatcaaatat agtaatcaat aataaggaat tacaaaaaaa atggatgctt gaaacagatt
    29881 ctaaattagc tatattccta cctaatccat tcgcaatagt tgctactaaa gttgcttata
    29941 atgattgtga agattggatg aatcaagtaa atgagtatat agatggtaat attaaatatg
    30001 tagaagattt tgttaatgag tatatgccta aagtaaagat aataaaatct caaggaactt
    30061 acttagtttg gttagacttt agagggtatg gattagatgc aaaacagctt gaatatgtaa
    30121 tgcttaacaa ggcgaaggta ttgctagatg aaggatacat attcggagaa gaaggagcag
    30181 gatttgaaag aataaatgtt gcttcaccta gaacaattat agaagagtgt atgaatagaa
    30241 taaaatgtgc atttgaagga ttataatagt aatatctaaa taatatattt gtgtatttta
    30301 aaaaaagact atgctaaaaa aatatttcaa agcatagtct tttaaagttt tatgatgagt
    30361 ttaaaaaatt tcaaaacgtt actattcact tatatgttta tattagaaat aattccacaa
    30421 tatactcatt ttctaaagtt gcacttttat acaccttgct tcaccaatat catgtgtaac
    30481 caaaatagta gacttattct cattcttaat aatactataa acatcatcac aaactaataa
    30541 tctagtctga taatcaagag ctgaaaaagg ttcatctaaa agtagaatat ctggatttac
    30601 agaaagtgtt ctaataagcg caactctttg tctcatacct ccagataatt cttttggata
    30661 catacttcta aaatcccata atccataagt ctttaaaagg ctttcaactc tatctaaaga
    30721 ttttttatct tttttgcctt gaatttccaa tccaatagtt atattatcca ttatatttct
    30781 ccattcaagc aaattatctt tttgaaacat atatccaata tttccagtaa tctttatatc
    30841 accactagtc ggttttaaaa gattagtaag aatatttaat attgtagatt taccacttcc
    30901 agaaggacca agcaaagtta atatttctcc ttctttcaag ttaaaattga catcctttaa
    30961 tacttcaagc tcgccttcct tagtgtagaa gttcatattt atatttttaa cttctactat
    31021 gttgtcattc attatgccac cccctataac ttttagctcg tatatattat gttattaaca
    31081 atatgaccta tttgtaccat ttttcataaa tataatataa atattttgtt tatttacgta
    31141 ttttcttagt aacttgtacg tataaattat agataaataa attataaggt aggggataaa
    31201 tttgagtaac ataataacga atttaataga gtcaatattt actaatccaa taactatatt
    31261 gtttttactt gcaataactg tgtattctgt ttttaaaata atagaaaata acagagtata
    31321 ttcatttgta agttcaaaat tagacgaaat caatagagac tataagacaa gtgagtttta
    31381 taaaaaggta agggatgact actatacata tagtaaagaa aatccttatg cagacgtaaa
    31441 tataacttca tttatagagg aagttgtatc tgatttaaag cataataatt tgccattgtt
    31501 agaaaaaatt agaagtataa aaaattcatc ttcaataagt atattacttg gggttttagg
    31561 tacgtttgtt ggtctttcta caatgctttt atgtgttgat actaaagaca ttataaattc
    31621 acttccttca actattagta gtatgcaaac tgcatttaca actagtatat ttggagttgt
    31681 attttctcta attataggtt actttactaa gataaaagat tgtgaacatg ttttgataca
    31741 aataatgtta aaatctgaaa atttactaac atctgaaata actcatttta agtcagaaag
    31801 aatggattta aaagtagaag aggtaaaaaa tacaataaaa caaataagta agtctataga
    31861 agctattgaa aaatttgata aaatatctaa agatttaaat gactttaatg atgaatttat
    31921 cagtggtata gaagctttaa aaagcctttt agaaggttct caaagttcta ttaagacatt
    31981 tgaccagagc gtaagaaaat tagataaaca gtttaatatt ttaaatataa aatttgtaaa
    32041 gctttttgat aaatatgata atcaagataa tataaataaa gagattttat ttgatataaa
    32101 agaatcttca aaaaatatat acaatgccac tgaaagccaa ttcaaaatta gagattatat
    32161 aaaaaatata aatgcaggat ttgctctata tgaaagaagt gctcaagatt tattaactaa
    32221 attaatgacc catgaaaata aaatatctca aaatcaaaaa atccttttag atgaaaagtt
    32281 taccttagat gactcaataa aaaatctctc aagtattatt gaaaactttt ctaatgacct
    32341 acaagttaaa ctggatatga tgtttgaaaa ttctttagat attcaagata agttagatgt
    32401 tatgtttaat aactctttta tgaatgatga agttcctctt gatagtgaag aattatttaa
    32461 ggatgatgtt aataatgtat ttaatccttt tagtgaagaa atttatgaga tagaggataa
    32521 agaaataaag gtcataggtg aggatgagtt aaatgaataa taaatataga agaactgtta
    32581 acagagaatt tgaaaagagt agcttttggc caacatttac agatttatta tctactgtat
    32641 tgatggttgt gattcttatc ttatttagct cagaaagtat ttcaggttct gttgaacaag
    32701 atttagctaa gaatgtcaat gcttctgttg aagaaacttt taaaaaaagt ggaatacctg
    32761 tgaaggtaga taaatctaat gggcaagtaa cttttggtga aaaaaccatg tttgatgtag
    32821 atagtgatgt tttaaaacca gaggctaaag aaatgctaaa aatgtttgtt ccaaagtaca
    32881 tagagactat ttataaagat tatggtgact atatatccaa aatagttata gaaggtcata
    32941 cagatgatgt gggaagttat atatacaact tagatttatc gcaaagaaga gcatatagcg
    33001 ttgctaaatt tatagtggga gatgaaatag gtgactataa atacaaagat aaagtgacta
    33061 agcatattat tgcaatagga aggtcaaaag ctgaactcat caaaaatggt gacaatagcg
    33121 tgaatagaga tgcatctaga agagtagaac taaaatacga aataaatatt aatcaaaata
    33181 aataattaaa tttttataaa aaaaaagaag gcagttggtg tgagctttaa gccttcttta
    33241 aggaaaaagt ttatttattt ttgttgatac ttaacatatt atagttttta gaagcagttt
    33301 gcaatatatt aaacgtaaat ggtcgtttaa aatgcataac tggatactac tgatgtaaaa
    33361 tatttcattt tatataatat aaaaattata cagtgtcaat tttctatatt attgtactat
    33421 aatctattat ttaaaatatt atgtaaaaaa atatcataaa aacgcatatc atgttataat
    33481 tactagagta ttatgaatat ggaggcgtag tttgtgatag aaataagtat aaaaaataaa
    33541 aaaaattcta aaattaaaac tttgatactt ttattgatag tatctatatc gatttattta
    33601 actggttgta ctacatcaga taatggaaat aatcaatcaa ataataatga ttctttgtct
    33661 agtagtatat caagtgataa gaatgtaaaa attcatttta ttgacactgg aaatagtgat
    33721 gcaatattga ttcaagatgg taaaactttt acattgatag atgggggaga taatgatgat
    33781 gagggattaa tggtagatta cctaaacaat caaggtgtaa aagatattaa atatcttata
    33841 gctacccatt ctcatgcaga ccatttaggt ggacttgatt ctgttgtcaa aaactttaat
    33901 atagaaaatg tttttgtatc gaatggttca gcagaaacaa agagttatag ggactttata
    33961 aatgctttag caaataaggg tttatcccca agtgtaccgc ttgaaaataa taagttctat
    34021 ttagaagatt cttattttga agttctaaat acaaatgggg gagatactac taatgaacaa
    34081 tctctagtcc ttgtatatac taatgggaat gataaagttt tatttacagg tgatgctgaa
    34141 gaaggtaccg aaaaagaaat actacctaag cttgagaaag tagacctttt aaaagtagct
    34201 catcatggtt ctcgtagtag ttcatctcaa gagtttttag ataaagtaaa tcctgaatat
    34261 gcggttcttt tagtaggcaa gggtaattca tatggtcatc cacatcagga gacaatgaat
    34321 aaattaaaaa aaatgggagt aaaagtgcat agaagtgatg agtgttcaga tataatattt
    34381 gaatcaacag gtgatggagt atttacaagt tgtaaagatg gaagttataa taaaggcgtt
    34441 agagaagatg gaaactctgg aaaatcaaac agtaatacaa gtaaaaatga ttcttttaaa
    34501 aataaacaaa atacatccaa ttcagaagaa atagtgtatt ttactccaaa aggtaagagc
    34561 tatcactcta caaaaaattg tagtgggctt tcaagaagta aaaaaatatt atcaggcaca
    34621 attgcagaaa gtaagaaaaa tgacccatgt gatatatgtt atggaaaata acaaaaaaac
    34681 aaccaattta tctataaagc ttctgaactt taaatcattt aaaaaataaa ataaatgcat
    34741 aaaaaaataa gctataatca atagataaca cattttatct atacgaatag cttatttttt
    34801 taagtatttt ttaatagcta tttaataact ctaaatacac cagttacaat acctacaatt
    34861 tcaacttctg agtcattgag cataattggt tccataaaat cattttctgg ctgaagtctt
    34921 attaaatttc cttctttaaa aaacctctta accgtagcag attcaccatt tataagtgca
    34981 actactatct gagaatttaa ggctgtattt tttttgtcta ctacaacgta atcttcatct
    35041 aaaattcctg cattaatcat actttcgcct tttactctta atacaaaatt gttactgccc
    35101 tttactaaac tggcagggaa tggaatgtat tcctctatgt tttgttgagc taaaatgggt
    35161 tctccagctg ttatttgacc tactaaagga agctctatta tttcttgatt agctccagaa
    35221 acatcattta ctttactacg ttctaaaact tcaatagctc ttggtttagt agggtccttt
    35281 cttatgtatc ccagtttttc aagtttattt agatgagagt gcacagttga agtagatctt
    35341 aaccctacag cagtacatat ttctcttaca gcaggtggat aaccttttaa tatgatttga
    35401 gactttataa attccaatat caagacttgc ttttcagtta gatctaaata cataacatca
    35461 ctcatttcca aacatatttt gtttttattt ccatacactt tatattttta attataacat
    35521 aatccattta tatctgcaaa catttgttcc tgatttttaa tcgtcctcaa tccattcaaa
    35581 attcttgact atatcacgtt ttacattttt cttatgagct gcataaagct gagtagttgt
    35641 gacattatca tggtcaagta agttttgaac atcatatata gaaaatcctg tttggattag
    35701 agaagttgca gccgttgctc ttaatttatg gggactatat ccattgtctc tagtagtatc
    35761 aagtggaata gatgtatatt tttttaccag tgttcttata gcctttgctg taattctctt
    35821 attttgaaga gacaaaaata aagcatcttt ttcttcatca tttaatagtt catctcttgt
    35881 tctttcgttt tgcaaataat cttttattac atgttcacaa gtatgattta taggcattaa
    35941 aacttctttc ccacgttttc tatatatttt aaattcacct cttgaaaaat taaaagagga
    36001 gatattgagt tctctaagct catttaatct aagcccgtat gtaacaaata atgctagtat
    36061 agctttgtca cgtaatttag tttttctcca atataccttt tctttctctg taagcccttc
    36121 acctgtttct actgattcaa gcatcttagc aacttcatct atctcaaggc gcttaatagc
    36181 atctggctga ggtttaggaa gttttattgg attgaatcca tcagttatat tattatctat
    36241 ctgagagttt ctgtataaga atttaaatag agtagagatg gatgattttt ttcttgctaa
    36301 agctctattg ttattttcaa aaatcaatgt gtttttttct gtatttttgt aatatctact
    36361 gcaataatca cctaagaata aatttatatc tcttgatttt attgtattaa aatcatcttc
    36421 tgtaatgtct tttacacaat ctgcatttgt taattctttg gtttcaatca aatatgaaca
    36481 aaaaaaatta atatcttcta aataagcaag tcgtgtagaa actgcaacag aaccttttaa
    36541 atatataaaa taatccttca taaatacagg aagtttattt tccaaaagta gacatttttc
    36601 tatgagttca ttttctttga taacaatatt atcaggttta tctgatttat tatgtacttt
    36661 tataattttc ttatcattat tcaaaattaa acctcctaaa actaaaatat aaatctttta
    36721 tattattttt tgatatttat actaagtgag tataaatatt taatttaatc attttttaca
    36781 tttttaagag attagcagtg ctttagatga aattatcact aactattccc taaatccaca
    36841 tttaaagact agttgaattt aagtactctt ttttatttct caatatattt atataaatat
    36901 attgagaaat tttttatgct ctactagaat cttttttata taatattttt atatgtttct
    36961 aacgaaacca aatattagta aaatatgtat ttatttaact aaagttttta aatgggctga
    37021 ctaagcttaa aatataggat attatgagag ttactattga aaaaataaac cctattgcca
    37081 taaagaaact tataaatatg ttatacttaa ctattaaact ggatatattc aagttatcaa
    37141 atccaaataa gtatgtaatt gaacttatta caaaaataac tataactata aagctcaggc
    37201 catttaagct attttttaaa tcagcactac taagtgacat atgtgtagat atagaataca
    37261 ttaaaaacat aaatataaaa tacttcaatg aatatacact aggtgttaac aacattattc
    37321 ttataaaatt ggaaatatca cctaaaataa tgtgtataaa accatttata tttaaattat
    37381 taatcatgct tacatataac tttaaatcta tattttgagt cactttcata taactatctg
    37441 gcagtaatat cttaaaaatt aaaataatca ttattgttcc acctataata ggtgcaattc
    37501 ctataaagaa atttcctata ctttgataaa gattatcttt tttatagcta tgacttacat
    37561 atcctagtat accatcattt ttactttcta ttggtctgaa aaacttaact gaatttattt
    37621 tatgcatgaa aattaaacac attatcaaat gactcaattc atgaacaaat gttcctatag
    37681 ctccagttac aataattcca gtttttccaa aagatgaaaa tataaattta ttatttagat
    37741 tttctgtaat gctaaaaatc aatccaaata caataaatat tcctatgaaa caaaaaatat
    37801 ttattacact tatttttaaa atttcgatta tataaatcat aagttaaatc ctcatgtaaa
    37861 agtatttaac tactctactt catatccatt acagcttaaa attttacaag cattttctat
    37921 atccttttct tttactaaga tatagtctgt atcataagta gaaattgcaa atatgcttat
    37981 tttgttgtct gctaacaaac tacttaactt agataaaatt cctacaagtg aaaagtctaa
    38041 aggacctagt atcttaagta ttctccactc cttttctgac ttaacatcag aaggaatatt
    38101 attatttaaa catacaacac ttaattcatc atcagttcta gttatagagt aaaacttctc
    38161 tgtatctatc catgttggta ttttactgtc attatttaat ctacatactg catactcttc
    38221 taccaataat tttaatttca taatgtatat ttcctccaat cttatttgtt tacttaagat
    38281 tatacattaa aagttacata aaataaaaca tataaagtaa aaaaggttca ctatagtgtc
    38341 ctatttctat agccaacctt taaaacttaa ttaaattcta ataaagagat atattatcta
    38401 ggttcaatta taagtttaat ggctgttttc ttatcacctt cgatttctat atcagtaaat
    38461 gcgggaatgc aaactaaatc cattccacta ggtgcaacaa aacctcttgc tattgcaatt
    38521 gattttatcg cttgatttag agctccagct cctatagctt gtatttctgc aacgcctcgt
    38581 tctcttagta ctccagccaa ggctccagct acagaattag gattagattt tgatgaaact
    38641 tttagtacct ccatttcaac atctccttgt taatttgtta aagtatccat tacctaaagt
    38701 actaaatcat aattgccatt tactaattac aatcatcatt taaagtatac ttttataaaa
    38761 atatacttct ataatcgttt taagaaaacc tttatttttt ttaaccattt tattatgaaa
    38821 aaactacaaa tttctttata ttctataagc attttccaat atttctaaat tttttatatc
    38881 tttgagctat aatttcctct ttatccatat ctttgtaatg atttaatctt tctaaaatgt
    38941 aagcttttat ttcttttgaa acagcttcta catctttttg tgctcctcca agaggttctt
    39001 ttataatctt atctattatt tttaaatcat ataaatcatt acttgtaagc ttcataacat
    39061 cacaagcttc tttagcttta gatgaatctt taaatagaat actagaaagc ccttctggag
    39121 aaatcacaga ataaactgaa tgttctaaca tacatacatc atttcctact ccgataccta
    39181 aagctcctcc actaccacct tcaccaatta caaaagtgat tactggaaca gaaagtttac
    39241 tcatttcaag taagtttctt gcaatagctt ctccttgtcc tctttcttct gcttctagac
    39301 cacaaaaagc tcctgatgta tcaataaacg ttattatagg tctattaaat ttttcagctt
    39361 gtttcataag tcttaatgct tttctgtatc cttctggatg aggcattcca aaatttcttt
    39421 ttatattttc ttttgtatct cttccttttt ggtgtccaac tatagtaaca ttaaactttc
    39481 ctatctgacc aattcctcca accatagaag ggtcatcttt aaaaagccta tctccatgaa
    39541 gttctaaaaa attagaacaa atatgttcta tgtattccaa tgtcgtaggt ctctttatat
    39601 ctctacttaa tgttaccttt tcatatgctg atagatgtga aaaagcatct tccttaagct
    39661 tttccaattt ctcattaagt gaatttattt tatcacttaa atctatatta tttgccttag
    39721 aaatagttat taattgttta atatcatttt ctaagacttt tattttttca ctattatttt
    39781 caatcaaaac agttcctcct ttatgcccta tttcttgtgc atagcaagaa tttgatataa
    39841 tacttccttc atttttcttc tatctactat catgtcaata aaaccttttt caagtaaaaa
    39901 ctcagaagtt tgaaatcctt caggaagttt ttgatttatt gtttgctcta ttactcttgg
    39961 acctgcaaaa cctatcaacg tatttggctc agaaattata atatcaccaa gcatagcaaa
    40021 actagcagtt actcctccag tagtagggtc agttagaact gatatatatg gcaatgattt
    40081 ttcttcaagc ttagaaagtg cttgagaagt ctttgccatc tgcataagag ataccatacc
    40141 ttcttgcatt ctagctcctc ctgaagcaga acaaataatt ataggtaaat tattttcagc
    40201 agcatactct attgaataag ttattttttc cccaacaata gaacccatac ttcccatcat
    40261 aaaatcagga ttcattacac aaataactgt tttaattcca tttattcttc cataacctgt
    40321 gacaacagct tctgactctt ttgttttttc cttataagag tctacttttt ctttgtattt
    40381 aggaaaattt agtggatttt gaaattctac atcagaatta aactccataa aagttccttt
    40441 atcaatcaat aaatttattc tttttcttgc tcttaagcca taatgtcttg aacattttgg
    40501 acatacaaat gaattttctt ctatgtcctt tctaaataca tgactatcac aacctttgca
    40561 ataggtccaa aatttatcat ctacactatt ctttttaaag ttgtcatcta aagaaatcgt
    40621 aacatactta gattcttttg atgataaaaa tttttttatc ataatctatt tactccttat
    40681 aatgtagcaa attctttctt cataaagaca tcttctataa atttggtatg atgagtatct
    40741 tctctaaact cctcacttgt tacaagtgcc ttttgaaatt ctacatttgt attaatacct
    40801 tctacaataa tttcgtctag agctctatat attctactta tacattcttc tctagtttca
    40861 gcccaacata ttaacttacc tatcatagaa tcatataaag gtggtatagt atatcctgca
    40921 tatacaaaag tatcaaatct aacaccaaaa cctccaggta aatttaatga ttctatctta
    40981 cctggtgatg gagcaaaatt ctttgatgaa tcttctgcat ttattctaca ttcaatagca
    41041 tgacctctaa aagtaatatc ttcttgttta aaaggaattt tatccccatt agctatagat
    41101 atttgaagtt ttataaggtc aagatttgtt accatctctg taactggatg ttcaacttgt
    41161 attcttgtat tcatctctat aaaataaaag tttttatctt tgtcaactat aaactcaata
    41221 gtacctgcac cgatataacc tactcctttt actatatcta ctgcaatttt atgaagtttt
    41281 tgtctttctt catctgaaag gtatggactt aaagattctt ctattacttt ttgatttcgc
    41341 ctttgcatag aacaatctct atcacctaaa tgtattgcat ttgaatgttt atctccaaat
    41401 acttgtactt ctatatgtct aggattttct ataaactttt ccatatataa atcactatta
    41461 gaaaatgctg ctagagcttc tgaacttgcc atatcaaaat ttgaaaaaag ttcttcttct
    41521 tttctaacga ttctcatacc ttttccaccg cctccacttg aggcttttat cataacagga
    41581 tatccaattt ctcttgcaac ttctaaagct tcttccttag ttttcaaaac agattctgaa
    41641 ccaggaacaa cagggatatt caattccatc atagtttctc ttgctctaga tttatctccc
    41701 atcaaaatca tttgttctct tgttggacct ataaaaataa tattattatc ttcacattgc
    41761 tttgcaaatt caggattctc tgataaaaat ccaaagcctg gatgaatagc atcacacttt
    41821 aatttaagag caagatagat tatattttct atattattat aactcttact tatattattt
    41881 ggtcctatac aaatagattc atcagctata tatctatgaa aacaatcttt atctatttca
    41941 gaatagatag caacagtttt tatacctagt tctttacatg ttctgatgat tctaactgct
    42001 atatcgcctc tatttgcaac tagtattttt tttatcaact taaatacctc ctactacaat
    42061 ggttttatct taaataaagg ttgattatat tctactagtt cttcattact aactaatact
    42121 tcaattattt cacctttaat ttcacttgtt atctcattca taagcttcat tgcttctaat
    42181 atacataaag tgtcgccttc ttcaactaca tcgccaactt taacaaagct atctgcatct
    42241 ggacttggag aatcatagaa tgttcccatc aaaggagcta ctactactga tagattctca
    42301 ttagatgtga caggtgtatc gtttacaact ggcttttcta aagaaagatc cactactgat
    42361 tcttgttgta cacttaaaac aggtgaactt gtagattgag cttttttaga tacttctaat
    42421 cttaaatcgc tactttcaag ttttacatat tctaagttag ttgagtctat ggcctttaat
    42481 aattccttaa tttcattgat gttcattttg ttaccccctt gtattattac ctggtgctaa
    42541 tattatatca caaaaaacaa atttataaaa gaaaaagtgc tgactagaga atcaacacat
    42601 caatatatct tttaatttta aattaacaac cagtaactta tatttgtttt aattttccat
    42661 tattaatata aattataagt ataaaatgaa taaaattcaa tattttttgc aaaatacaag
    42721 agaatacaaa ttaatacctc gggaattttt aagacaaata ccaatattat gcaatttaga
    42781 cttcgctttc tttcaaatta gtatcatttt ctttattttt acataggatg tactttaatt
    42841 tagctatcaa aacattgcta tataggttaa aagttattag aattgcagga attataaagt
    42901 aaactctagc acctataaaa ccaaaaacta ctgtaataag tattaatctt ttatttaaag
    42961 taaaaaaagg tatattaaaa atacttttgt cggatgtttc tggagtataa gaatatataa
    43021 ctccaaaaat caaagtaagc atacaaagtg gaagtagtgt ataacttgaa attattccca
    43081 aaaatcctat actttcaaaa tatttgctag cactatttgt ataaacaaac atgtatccat
    43141 ttaaatatgc gcatatacat gatataatgc caaaagttcc ccctaaggat tgagtgtacc
    43201 aattaaaaaa tttagattcc atatacctca cctcctaaaa ctgtatatat aatgatatgc
    43261 atttaaatag taaaatatat ctttatatgt ttctgaataa aattttgtta atttcattaa
    43321 tttatgttta agaaatttga agtatagtgt agtatatatt aatgtagatg aagttttata
    43381 gtacttattt catagtgctt aatcaagtta tcttattatg gattcaaaag ttgtttgtag
    43441 ggttttatat tttgttgagc tgaaaaattt attataaatg aagggatgtt ttcgctttgg
    43501 tagatacatt agaatttggt cttaaaattt tattttttat attatcaata atttggatgg
    43561 gtaaaataat gattttaaga actgataagc aaatagtaat caatcctttg cttattggta
    43621 tatctgcaat ccttgtgatg ttgcatacct cacagagtaa cattgaattt tttggattag
    43681 atgtccaata tataagaata gttttgtata taatatattc actgataatt ttaataggaa
    43741 tatgggctac taacagaaga aatggaattt tttagataat ctatttctat aaaatttaaa
    43801 ggttgctagt aacaaatcac taatattagc gttctgttac taacaacctt tattttgatt
    43861 atacacttaa attgaaaata gaatgattga ataagttgac agattatttt acattgacag
    43921 taattagaac ttcttgagat gtatttaaat catttttgtc gcttagtata acttttacca
    43981 ctgctttacc tgttttatta cctttaatta tcatatcttc acatgaaagt acactcttat
    44041 cacttacaga tacaataaaa tttaaatctt ttggaaggtt atcagtaact tcccagtatt
    44101 tataataact atcaattttc ttcgtaatta tttttctcaa atcaatactt tcaccttttg
    44161 ctatatcaac attatgatat ttagagtcca gtttatactg attatctttt gtatcaataa
    44221 aatttaaatc gcaatttaca tccacaccat tatgagaaag agaatttact acatcgtcat
    44281 caatcaaata attattggca agatttattg aatccatatc ttttagactt aaagcttcct
    44341 taggaacctc ttttatatta ttattccaaa aaataaaatt gtctacattt tcaagatatg
    44401 atataccttt taaatttgaa atactctcac cagttgcata aaattctcca tctaaagcct
    44461 ttatattgct tatagtcatc tcatctggat ttatatatct ttttacaact gctcttaaat
    44521 ttgcatcagg aaaaatatct ttaagttgat tttcgctcaa aaccttatca tttgaattta
    44581 ttggacttaa agctgctgca gaaataataa atggtattaa attagctaaa ttcatagtac
    44641 cctcccacat aaatttttta ttataataat ttaatttcta tgagagggtt ctgtttcctt
    44701 gttatatata cctactttcg tacactttat taatataaat taaaataaat ttctactatt
    44761 aaacttataa acatattact agttacgttt tttagcttca catctaaata ttcgcatacc
    44821 ttgtgacata aatttgtctt catactctgt tgtaacatta ttttcatact cactatttcc
    44881 taaatcaaga gaaatattct ttaatagcca attatttgca gcaatttcat ttaaactaaa
    44941 ctcgaataat ttttcattat ctgttttaaa gtgaatttcg ccatcatctt ccaaaaccct
    45001 attgtacatt tctaaaaatc cagaatgagt gagtcttctt ttactccatc tatttttagg
    45061 ccatgggtca cagaaattta tataaattct cgataattct ttagcttcaa agtaatccaa
    45121 aatattgctt acatctcccc ataaaaatag tatattattc aaattagaag catctgcttt
    45181 ttcaacagct tttaaaagaa cttcttcctt aagttccatg gcaatataat ttatgtcagg
    45241 gttctgctta gctaaagttg ttataaactt accttttcca gtcccaaatt caacatgtat
    45301 tggattatca tttctaaact ttaaattcca cttgcctttt aatttgtcta tatcgtctct
    45361 taaaacatat tttgtataac ttaaaagctt ttcatctgca cctttttttc gtcttcttct
    45421 cacaataatt ctccttacat ataaaaaatt agtaaaatac atttttatta tacattatct
    45481 caccaaaaaa taaaaagaac tctcttaaaa tagaaattta tttctataaa gagagttcta
    45541 aacttactaa aaacttaatc ttagtggcac cctgaacaac cagagcatcc tcctccacct
    45601 tgatctttca tattttcagg aataactcta aatccaaatc ctgtatcttc tattattata
    45661 tctccatact gactatattc atcagagctc attacaaatt gtaattctcc aacttcataa
    45721 gttaagtcat cttctttttt ctcatctaaa gctaatccaa aagaaggacc tccacaacca
    45781 acacctgcaa agtatactct tatattatta ggtttatctt gattgtcttt taagatactt
    45841 tttaaagtat caatagctgt ttctggtaaa gtaattttca tcaaatcatt ccctttcaaa
    45901 tattttatta aaacaatatc tattatatac ccatacaagg tacataatca attagttttt
    45961 gcatatttta ctaaaacttc tacctaatat tacctaaggc tttaaaatat tttatataat
    46021 attttattac cttaaataaa taccctatca taaacttagt aaacaaataa aattattatt
    46081 ctaaaaaata taataatttt a
//
LOCUS       DAMJWC010000028        45547 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMJWC010000028 DAMJWC010000000
VERSION     DAMJWC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.028"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            98..937
                     /locus_tag="PC503_001786"
     CDS             98..937
                     /locus_tag="PC503_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010293327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2527759.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITKYLYFNGL
                     DGK"
     gene            1052..1291
                     /locus_tag="PC503_001787"
     CDS             1052..1291
                     /locus_tag="PC503_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527760.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1462..1638)
                     /locus_tag="PC503_001788"
     CDS             complement(1462..1638)
                     /locus_tag="PC503_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527761.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1692..1788)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2143..2817)
                     /locus_tag="PC503_001789"
     CDS             complement(2143..2817)
                     /locus_tag="PC503_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2527762.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3037..3591)
                     /locus_tag="PC503_001790"
     CDS             complement(3037..3591)
                     /locus_tag="PC503_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2527763.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYYK"
     gene            complement(3669..4034)
                     /locus_tag="PC503_001791"
     CDS             complement(3669..4034)
                     /locus_tag="PC503_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527764.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4499..5284
                     /locus_tag="PC503_001792"
     CDS             4499..5284
                     /locus_tag="PC503_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527765.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEGGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5381..6205)
                     /gene="pdaA"
                     /locus_tag="PC503_001793"
     CDS             complement(5381..6205)
                     /gene="pdaA"
                     /locus_tag="PC503_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2527766.1"
                     /translation="MKKDSLKKYIMIGAFALTLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6426..9545
                     /locus_tag="PC503_001794"
     CDS             6426..9545
                     /locus_tag="PC503_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2527767.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANKIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINFIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9563..10162
                     /locus_tag="PC503_001795"
     CDS             9563..10162
                     /locus_tag="PC503_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF2527768.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10389..12518)
                     /locus_tag="PC503_001796"
     CDS             complement(10389..12518)
                     /locus_tag="PC503_001796"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF2527769.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12784..13032
                     /locus_tag="PC503_001797"
     CDS             12784..13032
                     /locus_tag="PC503_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527770.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13198..14589
                     /locus_tag="PC503_001798"
     CDS             13198..14589
                     /locus_tag="PC503_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF2527771.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14704..16173
                     /locus_tag="PC503_001799"
     CDS             14704..16173
                     /locus_tag="PC503_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2527772.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16238..16831
                     /locus_tag="PC503_001800"
     CDS             16238..16831
                     /locus_tag="PC503_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF2527773.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            17013..18359
                     /locus_tag="PC503_001801"
     CDS             17013..18359
                     /locus_tag="PC503_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2527774.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18541..18912
                     /locus_tag="PC503_001802"
     CDS             18541..18912
                     /locus_tag="PC503_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF2527775.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18905..19594
                     /locus_tag="PC503_001803"
     CDS             18905..19594
                     /locus_tag="PC503_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF2527776.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20114..20980
                     /locus_tag="PC503_001804"
     CDS             20114..20980
                     /locus_tag="PC503_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2527777.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21222..22031
                     /locus_tag="PC503_001805"
     CDS             21222..22031
                     /locus_tag="PC503_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527778.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22175..23239
                     /locus_tag="PC503_001806"
     CDS             22175..23239
                     /locus_tag="PC503_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2527779.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23267..23986
                     /locus_tag="PC503_001807"
     CDS             23267..23986
                     /locus_tag="PC503_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2527780.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            24010..24594
                     /locus_tag="PC503_001808"
     CDS             24010..24594
                     /locus_tag="PC503_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF2527781.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24596..25945
                     /gene="pabB"
                     /locus_tag="PC503_001809"
     CDS             24596..25945
                     /gene="pabB"
                     /locus_tag="PC503_001809"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF2527782.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25935..26678
                     /locus_tag="PC503_001810"
     CDS             25935..26678
                     /locus_tag="PC503_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDF2527783.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDIKYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FVKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26712..27413
                     /locus_tag="PC503_001811"
     CDS             26712..27413
                     /locus_tag="PC503_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527784.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27439..28011
                     /gene="folE"
                     /locus_tag="PC503_001812"
     CDS             27439..28011
                     /gene="folE"
                     /locus_tag="PC503_001812"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF2527785.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28075..28866
                     /gene="folP"
                     /locus_tag="PC503_001813"
     CDS             28075..28866
                     /gene="folP"
                     /locus_tag="PC503_001813"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2527786.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28877..29242
                     /gene="folB"
                     /locus_tag="PC503_001814"
     CDS             28877..29242
                     /gene="folB"
                     /locus_tag="PC503_001814"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF2527787.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29235..29741
                     /gene="folK"
                     /locus_tag="PC503_001815"
     CDS             29235..29741
                     /gene="folK"
                     /locus_tag="PC503_001815"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF2527788.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29722..30507
                     /gene="aroF"
                     /locus_tag="PC503_001816"
     CDS             29722..30507
                     /gene="aroF"
                     /locus_tag="PC503_001816"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2527789.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30762..32552
                     /locus_tag="PC503_001817"
     CDS             30762..32552
                     /locus_tag="PC503_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2527790.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32570..33736
                     /gene="rpoD"
                     /locus_tag="PC503_001818"
     CDS             32570..33736
                     /gene="rpoD"
                     /locus_tag="PC503_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF2527791.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33901..34590
                     /locus_tag="PC503_001819"
     CDS             33901..34590
                     /locus_tag="PC503_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2527792.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34604..35701
                     /locus_tag="PC503_001820"
     CDS             34604..35701
                     /locus_tag="PC503_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2527793.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35764..36336
                     /locus_tag="PC503_001821"
     CDS             35764..36336
                     /locus_tag="PC503_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2527794.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36396..36863)
                     /locus_tag="PC503_001822"
     CDS             complement(36396..36863)
                     /locus_tag="PC503_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2527795.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37249..37725)
                     /locus_tag="PC503_001823"
     CDS             complement(37249..37725)
                     /locus_tag="PC503_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2527796.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37845..38936)
                     /locus_tag="PC503_001824"
     CDS             complement(37845..38936)
                     /locus_tag="PC503_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF2527797.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFIPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLLTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38929..39318)
                     /locus_tag="PC503_001825"
     CDS             complement(38929..39318)
                     /locus_tag="PC503_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2527798.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39510..39956
                     /locus_tag="PC503_001826"
     CDS             39510..39956
                     /locus_tag="PC503_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527799.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEELDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40220..40945
                     /locus_tag="PC503_001827"
     CDS             40220..40945
                     /locus_tag="PC503_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527800.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40932..42176
                     /locus_tag="PC503_001828"
     CDS             40932..42176
                     /locus_tag="PC503_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527801.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLIVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            42256..42933
                     /locus_tag="PC503_001829"
     CDS             42256..42933
                     /locus_tag="PC503_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527802.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQVSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42934..45495
                     /locus_tag="PC503_001830"
     CDS             42934..45495
                     /locus_tag="PC503_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527803.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVKNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIVCTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
BASE COUNT        18498 a         4641 c         7654 g        14754 t
ORIGIN      
        1 ttaaagattt ttttagtata ttctaatact atagtattat agagtaataa tgttgattta
       61 aaataaaaat aagatttcgg aggagtttat tatataaatg aaagattact ataaaatagg
      121 agagatatct aaaatatatg gaataggtag agattcatta atgtattatg aagaaatagg
      181 cattctaaga ccagttagag atataaatgg atatagaatg tataatatat cagatatatg
      241 gaaattaaat ttaataaaag aatttagaag cttgaacttt ccaatgaaga aaataaaaga
      301 atacctagat gacagaagta tagagtctac gaaaaatatt ttaaatgaag aactcgattt
      361 aattgataaa aaaatagctg aatttataag ccataaggaa aatattataa aaagattgag
      421 ttcaattgaa agtgtaattc aaaatacaaa aatagatgag atagaggttg tatatataga
      481 aaaaagaaaa gctttagaat taaatgctga tataaagagg gatgaagact tcgatttttt
      541 aattcaaaaa cttcagaaag aatatgaaga tagatttaat atacttggaa acaacaatat
      601 tggttctgcc ttttctactg aagcaattaa taaaggcata tttaatgagt ttaaatctgt
      661 attttgtttt ctggaaagta atgagaaagt atataatata gtttttgatg aaggatatta
      721 tgtaacttta aattatactg ggagtaattc taataataag atgtatatgg agaaggtgtt
      781 taaatttata gaagaaaata attataagat aattgctgac cctatagaaa tctataagat
      841 agatatacat gagactggaa ttgtagagga gtttgtaaca gaaattcaag ttcctataac
      901 taaatatcta tatttcaatg gattagatgg taaatagaat gaaaaaatgt tgatttggca
      961 ccgatttgcc actgtgttat aaaatcggta gcaaattata ttttaaatta taagatagca
     1021 tgaaaaaata attgtttagg gggttataaa tgtgaaatgt tctaattgtg gaagtgtaaa
     1081 tattgaaaag ggaattttaa caactggtgg catatatgct gaaactattg gattaaaata
     1141 tagaggagat ggaaaattag ataaagttat aaataaaact tttccagtac aatctactat
     1201 atattcagat ttatgtttag attgtggcga aatagttaga acctatataa aggataatac
     1261 tgataggaat tggtgtaaag ataagaaata gaataatttt tgaagttgaa ttttattaaa
     1321 gatacaagtg aaaaagtata aatgggaaga aattgttata tggaagaaaa ctttgcatat
     1381 atggaagatt agttttttaa tataataaca tttttaaatg tagataaaac taaaaagggt
     1441 tctctagaaa acaatttcta tttaattata cttacttacc aataccatca cttgatgtaa
     1501 acaagattct actacatttt ctccgtactc tagtataaaa tcatctagct gtgtatctat
     1561 aaaatcacaa taatcatata aactactaat ataagcagtt aacatgtgtg tacatttatc
     1621 catttcatct ctaaacatat atattactat ccccctaaaa aactttcata aaacaaaaag
     1681 aacaatatct ttttggcaac tggctgacat aactcatagt ttattttata agcgttagtc
     1741 cctatagctt tgcgtcacta aatttctcta gttttgccga tttagtttta ttctacaact
     1801 aaaataatac actaggataa gttattgttc aacatacttg tcagaaaatt gaaatattta
     1861 acaatatctt aacaatatga aatctatttt tcactcaaga aacaaactat atgtatagaa
     1921 tgtttaataa aaattatatt tagttttgta ttgaagtttt tgtattaaaa agtttagttc
     1981 acaagggtta cttggctaga taatagataa acaaaaatat cttgaaaaaa tatatatgaa
     2041 tggcaaaaaa caagggatga attttatata gactcatccc ttaattattt atatattgac
     2101 cttgattaaa tatattatta tttttaagct tcaattttta tattatattt ctaaagtttc
     2161 tataagagga ttatcgctaa ataattttaa taaatttgtt tttttatatc ctttaggtaa
     2221 cttagtatat ataactactt ctaaccaatc cccatcaagg cgtttaatat tcatgtttat
     2281 aatttcaata ttagattttt taaatttacc ttcaatatat tctatggaat cagtgctgtt
     2341 agaaatttta agagaaactt gctctgctgt agggagtttc atccatttcc tatctctatg
     2401 aagtgttatc tgtacaataa caataatgat acttgaaaca ataccaacta agtataatcc
     2461 agagccaatg gcaagacctg taccggctgt tgcccatata ccagcagctg tagtaagacc
     2521 acttactgat tgatttctaa taaatattaa tccagcacct aaaaaaccta taccactgac
     2581 aacttgtgct gcaacgcggg ctgggtctag accaatacct ggagtaccca ctatatcatt
     2641 aaatccatac ttggaaacaa tgattataag tgctgaagct aatgccacta taaaatgagt
     2701 gcgtattcca gcttctttta gtctattctt tctctcatat ccaattaaag ccccacagaa
     2761 accagcagta atgattcttg ctatatattc aaattgaatc aatatatgat ggttcattta
     2821 tctagcaccc ccttctatat aatattatat atactataat actacatttt ttatgtgaat
     2881 atagtaaagt ttaaaattta tataatagtt atatatgaat ataaaatgta taaacgtata
     2941 ttatgtatat aaaaatgata gaaagcatct aattttaaat gattaaagag caagcttaaa
     3001 taaatcaaac ttgctctttt aacatagtgt atgtttttat ttgtaatagt tagataaaaa
     3061 tttatctgtg ttttttacat ctgcaaaact gttctgtagt gatgccatga atacttgatg
     3121 tacagtattt gcattaattt ctatattatt ccaagataaa ttcttcgttg tacatgcatc
     3181 gcttattaga gttatgtcgt atcgaagttt ctttgctgtt cttacacttg tatcaataca
     3241 catatggctc atcattccac agattactag attagtaata ttttttttct caaggatact
     3301 ttgcaaatct gtttcaaaga aactatctgg tgtgtgttta attataattt cttcattatc
     3361 tagtggaaaa acaattttat ttatttctga accatgagta ttaggaagaa aaaaagaagc
     3421 tgttttatct gttgatatat gctgtatatg aataactggt aaattgtttt ttctaaaaaa
     3481 cagtagtatt tttttagcat tttcagcagt ttcttctgat tgaaataatt cacattttcc
     3541 atttttaaaa taatcatttt gaatatcaat caatattaaa gctatagaca tgattatacc
     3601 tcctatttat ttttattata atactattgt aaaaaatgta aattacttac tttttggtat
     3661 gtataggatt acttattgta gcaaattcct ttattatcta gaatttcttg ttgaccatgt
     3721 tcaagcatat attcgattcc tatttcttgc attatttcca ctgcttttaa cattttttta
     3781 ccacgattag taagaaaata ttcaacatgt aatggatatc cagcagaact tattttatca
     3841 ataatcccaa aatcacgtaa ctcttttaat tgttgaatca acattttttg atttattcca
     3901 taaatattat gttgcaattc agaaaatgtt ttattagatt gtcttaattc aaatataagg
     3961 atagttttcc attttccttt gattatgtca tgtacaattt caagaggaca tgtatattca
     4021 gctcttattt tcatagcata tcacccccag taaaatgata ataaattata tcacttgtct
     4081 tgtgatatga caaatatata tgaactgtat ataaatttta tgttttatta agttctaaat
     4141 ttcttctatt gtagttcata tttagtacat aaataattag taagatataa gtaaataaat
     4201 atataacatg actatagaaa tttaacttta aaataactta tgataattta gaggaggaat
     4261 atatatgaat atatcaagaa aagctatgaa aataatagaa ttagcacaaa aaattgcaaa
     4321 taagagaggt atttcagtag aagaagcttg gagtgaagca gtaacagaat ataaaaataa
     4381 atacgaacat attgcataga tatttaaaaa tttagaatat ttggtagaat ataatgattt
     4441 taaatgatac tataaattat aaggtatatc attattaaca tagaaggagg atatctgctt
     4501 gattgtaaaa atagataata ctttagaaaa agaattttgg caatatgtat cacatgaaga
     4561 aagtttaaat ttattcataa ttggatacgt tgagaattat ggatttagct ctcaatatca
     4621 agatatatgg tctcaggtag aaggtggaaa tataacctct ataatattaa aaaataagtc
     4681 aacacttata atttatagtt ttaaaaataa ttttaatata ggagaaatga agaatcatat
     4741 aaaagattta gatgtagaaa gcataagtgg aaaaaaatgt gtaatagata gactaataag
     4801 taaatacaaa gatttttatg aaaaactaga taataaattt tgtgtattaa aagaaataaa
     4861 agaaatagat ttttccaaca tgaaggagta taaaatagaa aatgctcagg aaaaagatat
     4921 tgatgaaata ggaaaacttt taaataggtc agactataaa gtaagtaaaa attacataga
     4981 agaaagaaaa gttcatttaa aagagggaaa tgtaagagca tattttatta gaaatgatga
     5041 tactatgatt agcactgtgt caactggtat ggaaactagt tttttggcaa tggtggtctc
     5101 tgtaagtaca gataaaagat ataggggaaa aggacttgca agttatatgg tttacaattt
     5161 gagtaaagaa ttgttgttag aaggaaaagt tccatgtctt ttttataata atgatgtagc
     5221 aggtaaaata tatcataata taggatacaa agagataaat gaatggacaa ttctttttaa
     5281 atagctataa aaaataaaaa actctatcga gaattaaagt atttataaat aactatattt
     5341 ttactataat tcatgataga gtttttttaa atttatgata ctatttttta ttatttaaat
     5401 aatcaagtgt tttaagttta taaccttctt tttcccaatg tgtaagaacc tcatctaata
     5461 tctcagtatt tgttgatgaa tttggatgca gtaaaactat tgcaccagga tgagttcttg
     5521 aataaatttt gtttttggca aattcatgag taggttgttt cttttcatac caatctacat
     5581 aagcaaaact ccaaaatatt gatttatatc ctaaatcttg tgtatatttt aaagattgtt
     5641 cgctaaattt acccattgga ggtctaaaat acttaggcat ttcttttcca gtaacatctt
     5701 tgtatgcttt ttctacactt gtaatttctt ctttgaattt ttcaaaatct gtaatacctg
     5761 ccattgatgg atggcttttt gaatgattac aaactaaatg tccttctttt tccatacgct
     5821 ttattaactc tggattgctt tttatataac tttcaactac gaaaaattga gctttagcat
     5881 tgtgtttttt aagcgtatct aataattttg gagtgtttcc actttcatat ccagcatcaa
     5941 atgatagata tataactttt tcattgggat ttcctacata ataagctccg tattttttaa
     6001 aaaaatcagc ttcttttata ggtgatggct gtttaccatc ttccctaggg ttaaaatacc
     6061 aatcatattc atgtgtgtcg agtgttggac tagaaatttg agtttttgtt ttatctaatg
     6121 atttaaaatt tatactagca attccaaaaa gtgttagagc aaatgctcct atcataatgt
     6181 atttttttag gctatctttt ttcacaattt cacctcttat ttaaaattta aagtatattt
     6241 cttataatat agtttgaata tttatagtta aaaatattca catatacaaa taataaatga
     6301 aagaagttta ctgtaagata taaagttgat attaattatc ttaaataaag tgtatataaa
     6361 tgataaaata taaagagaaa tgattgtaaa taagttaggc tggtttaact tgaagggata
     6421 taaaaatgga taatataata agtgtattga atgatgttgt ttttttagat atagaagtta
     6481 gtggattaga ttgtttaaat tcagaaattt tagaagttgg agctgtcaag gttaaagact
     6541 ggaaaatata tacctatgaa tcattaataa aaaacaaatt tgaggtacct atagaagtat
     6601 tctcagtatg taaaaattta gataaaaatg atttagaaat agctaataaa atagaactgg
     6661 tggaagatag acttgtaaat tttgtagaag atagtttcat tatatgtcat gatttaagtc
     6721 tgaaaaaaaa gttttttgag tatcatatgc caaagttaaa aaataaattt attgatttaa
     6781 ttgaattagc agttatttta gaaccatatc ataaagatta tagcttagaa tacttaaaaa
     6841 atactttaac aaattgtaat tctaaagtgg aaaatagagc tttatcagat gctattgata
     6901 taataaatat tgtaaattgc cttttagtaa aatttaataa ctatgaaaaa actactttgg
     6961 agccattgag ttttaaaata aattcatatc ttaaaaaatt taatcttcca acatgggaat
     7021 ggagcaaatt tttagaagag gcaaattatg atttatcaaa taatataaat ataaaaaaag
     7081 aatataatat atttgactca aaagaagaaa agaagaagga aagagaaacc ttaaaaattt
     7141 taaatgaaga agaaaaaaat tatgaagaat tattaaaata caaaactatt tgggagaata
     7201 aagaaggatt tacatatgaa tatagacctg gtcaatatga gcttactaaa acaataagag
     7261 agttgtttag aaatagcgaa gatgaagaaa aaattgcatg tatagaggca ccaactggta
     7321 taggtaaaag tgtaggatat ttattgcctg caatattaga ggctagaatt aataaaaaaa
     7381 gattattaat ttctactgac acaaaggaat tgcagataca attaataaat aaagatattc
     7441 caaatgtgtt agattctttg ggtctaaatg gaaaagtaag ttacggatat ataaagggaa
     7501 aaaataacta tatttgtata gatagactgg aagcatatat agatgattat gagtctcaaa
     7561 accctactaa aggagaaatt ttatctttaa tatttttgaa gagattagtt gaaggtggca
     7621 agtatggaga tatagaagaa ataaattatt tagtgtttga caacttcaag gaaataagta
     7681 ctcacttaag aaatgtaagt tgtgacccaa atatgtgcag acctaaaaaa tgcaaaaaag
     7741 attgtttata taaaaacaga atagaagaat taaaagaaga acatataaca gtagtaaatc
     7801 attcactatt agctaaatgg ccgtataagg atgaaaaacc tttagaaaat ataatagtag
     7861 atgaagcaca taatttgact gaaaaaggat atgatttctt ttcaagtatt ataaattcaa
     7921 agtctttaag gtacttatta caagaaattt atccttacga gtttattcaa aatagtagct
     7981 ttatatataa aaaatatagt agaaatatga gaaaaataaa ggcttttgat aaattttata
     8041 atgtattaaa aattggaaga gaagataaac aaaaaattgc tagaagtata aatttcatta
     8101 ttgaagagat agattcaata ttaaagtttg gtaattgtaa tgaatataat aatgtaagta
     8161 attataattt aagatgggaa ctgaatttgc aaatagatga aattgtggga aaactaaaaa
     8221 aagatggtat agatactgaa ataagttata gagcctatag tgaaaagata aagttgagtt
     8281 gtgagaaaat aataaaaaat ttagtttcaa taataataat aatttatagg aatattgatg
     8341 atgatagtat agataaagaa gcagatatat ataaatttgg aaaggcaaag acaagagatt
     8401 tagaggatat aaagattata tttgaaatct ttttagagta tgatgaaaag gatgattatg
     8461 caaggatagt tgaaattgat aagaattata atgactttga atttcgagta gtaccattaa
     8521 aaatagcaga tttatttgaa gaaaatattt tatctcaatt agaaaaagga atatttttat
     8581 cagcaacttt gagtttatct gaaagtatgt cttattttaa aaatacatta ggaatagaca
     8641 gagttaagaa tgtggaaaag attatagaac caatttttga ttataaaaat agagtctctg
     8701 tagttggatt ttctgatatt tgtgagtaca gaaattctga atttccaaat gagatgagta
     8761 aaattatatc taatatatca aagattacag aaggtcatac attagctctt tttaatagta
     8821 aagatagaca agaaaaaact tatgaaatat tgaaaaaata cttacatagt tttaacttag
     8881 aaatttatgc tgataaaaag ggcattagac accttaacga tttaaataga aaatgtgtag
     8941 tacttggctc aaaaggatgt tttgaaggcg tagacattcc aggggatggt ttggtttgtg
     9001 taactttaga caagcttccg aatctaaatc ctaaagaccc tttgtatttt actataatga
     9061 agaagtatgg tatagactac tatactataa attatcctca aatgaccata aaggtaaagc
     9121 aagctatggg gagaatttta agaagcaaat atgactatgg atgttttgtg atttttgatg
     9181 taggaactaa tataagtgtg ttaaagagat tagagaaaga tttacacgat tgtaaaattt
     9241 caaaggttaa tagcaatgag ttttatactt atataaggcg acatttaaat aaatctagaa
     9301 gtttaatact aaaatctgtt atatttgata ctataaaagc gttgaatgtt gatgctaaaa
     9361 tggataacaa tgatgttgat aaggatatta taaaaaaaga tataaatgaa aatataagac
     9421 aaagagctgt aaaaggagaa gtgtaccata ttgatattat aaaaaaagat atgaaagtaa
     9481 aatattttga tagaaactat cttataaatt tagatatatt tatgagagaa gaagataaaa
     9541 attaagagtg ggagtgatat atttggcaaa acaaaagttt tatgctgtga aaaaaggtaa
     9601 aaatataggt gtatataata catgggatga gtgcaaaaaa caagtaaatg gattctcagg
     9661 agctgaatat aagagttttt ctacttttca agaagctaaa gaatatattg atgggtcaga
     9721 aaaattgagt tttcaagaag ataaggagtt tatagaagca tatgtagatg gaagttatga
     9781 acattcagta aaaatgtatg gttcgggtgt tgtgatttta aaaaataatg aagttataaa
     9841 aacttatagt gaaaaaggaa aagagaaaac tttagtaagt atgagaaatg tagctggaga
     9901 gatagaggct tctaaaattg caatgcagta ctgtattgac aataatgttc aaaacttgat
     9961 tttatacttt gactatgaag ggattgaaaa gtggtgtact ggagtttgga aaacaaataa
    10021 agaaggaact atagcatata aaaatttcta tgacagtatt aagaataagc ttaatgtaaa
    10081 atttacaaag gttaaagctc attctggaaa taagtataat gaggaagctg ataaattagc
    10141 taaaaaagct attggtgtat aataaaaaaa tatttataca taattacatg gtataagagt
    10201 atatctaaat tcctacttta taattaaaca acttgtaatt aaataaattt tgattaaaaa
    10261 agcagattgt attatgaaaa aataagtatc taatttataa acaattaata atagtattaa
    10321 ttagatacaa cttatttaat ataataaaat ctgcttttta tataactata aaattttact
    10381 acattctatt agaattgccc ataaatacct tcaagttctt cttttaatac ttcagggtca
    10441 tttataccaa tagacatggt tctagccagt atatttgctt ggtcataagt tgatgtccat
    10501 gagaatacac cacctagaca atttctaaga acatattgag tttttaagaa tattgataaa
    10561 gcatcatcat atgacattgc aaaatctcca tccttaacta aatacggaac ttgagcagta
    10621 ttatcaaatc tatattcata tccattttta tttatataat cccttctaag ctcatcataa
    10681 gttcttgtta tagtagcacc taatcttcca taaaatggta taccaagaag gattttttca
    10741 gaaggcattc cagcattctc aagatttctt accattgcat caacactata tcctggcaaa
    10801 gataagtctg aatcaaaaag atttgcttga tgttttctac catttgggcc tgtttcacct
    10861 gctgtaaaat cataactcat aagattaaaa taatctatta taggagctat tttatctatt
    10921 tcagcacttg aatttatata tcctctatct cctgttccag ctacactaag ccatttatca
    10981 tctcctataa catctcttat ggcagttagt aagagtgtaa agttttctct atcttgaggt
    11041 cttgatgtta ttccagatgc actacttcca ggatattccc agtctatatc tattccatct
    11101 aaagcatatt catttatcat ctgattgacc tgtcttgcaa aattatatct agatgtaggt
    11161 gttaatgctg catcagagaa tccttcagct ccccaacctc caatagctac aattactttt
    11221 aagctaggtt tttcaccttt aagagcaagt aattgattta aaaatctagg ataaggaata
    11281 aacaaatttc cagactggtc tatctcagca aaagcaaata taactgcatc taatagttga
    11341 gcatctacat tagttggatt tccaagaaca tattctgcta caattggatt tatatctgga
    11401 cagtttgcat tttcaactat tggattgtat gggtctgtta tttgtggtct aactaatttt
    11461 ttagaatctt ttaaagtttt catagctatt tttttagtat ttttttcgct agtataatcg
    11521 tagtttttat aattatgttt atagaaatct tcataactac tatcttcttt gttatagcta
    11581 gaatttattt tgtcacaaga ttcatcttta tcatagttaa aattcatttc atcacaagac
    11641 ttatctttaa acttatcttg tttggagttg tgaactttgt tagtattttt agtatgtttt
    11701 ttctcatgat tgcaatcatc tttaatatca gtcttgtgtt cttgtttaca gtcaagagct
    11761 ttgttcaggt agtcatgatg ttcatgttca cagttacatt cattttcaat gtttttagta
    11821 tgttcttttt tccagctaca agtattatca attttcttgc tcacttcttc atcattataa
    11881 ttatctggta caaaacataa gtaccagtcc atacatgaat atttcttatt acaactgtta
    11941 actctatttt ttaattcctt atagttttta ggataaggta aaatcactgg cattccagga
    12001 aaccagtttg caggagtaac tatattatct ctatcactag tctgaagtgc atctactatt
    12061 ctaagtattt ctggaatatt tcttcctgta gttagtggat aataaagaat cgttcttaga
    12121 atttgattat tatctataat aaatacagag cgaacagttg atgtatcact cattggtttt
    12181 gatatcatgc cgtataactt ggcaattctc atatctctat cttctataat aggaaatgga
    12241 atttctacac ctgtaagtaa agaaatatta tacatccaag ctaaatgtga actgttacta
    12301 tcaacactta gaccaattag ttctgtattt ctttttttaa attcgtcata atatttagca
    12361 aaacataaaa attctgtagt acaaactggt gtaaaatcac caggatgtga aaataaaaca
    12421 atccaattac ccttatagtc agagagtcta ataggaccat ttgttgtatt ggctttaaaa
    12481 tcaggagcct ttgaccctaa acttggcaaa tttggcatgt aaatcacccc tcaataaatt
    12541 atcatttatt ttattctatt aattaataca tattagtgtt actattttat taaaagttaa
    12601 gtaatcctta tgtcaaaaaa agatatttat taaaaagatt taatattttc ctaatataaa
    12661 tgacaatagt aattgctatt tttttactaa tttggtatag taatggataa ggggtagtgt
    12721 caattttagt gattatacga ggtgagtgga ttgaaaaaaa ttctaagaat tttagttatc
    12781 tccatgatga tatgttttgc aatgactttt gcattagtgt taataaattc agttatggga
    12841 gtacatatag gattggatta ttactttttg atgggaagtg tgcttacagt ttgtttaaca
    12901 attggaattg ttttatgcaa tgctagaaaa atatttgata gcaaagctat acacaagaca
    12961 agaacgaaaa ctgtcagtaa taataaaaaa caaaagagtc attctaggga tataaaaaga
    13021 aagatatcat aatttatgta aaggaaatat ttatgtataa aataatgatt gataggtaaa
    13081 ataaaaacac gatttaactt gtgtttttat tttttttcaa gaattatgat ataataacca
    13141 ataagaaatt tagtttacca taaaatataa agattattaa atggagaggg aactataatg
    13201 aattttagag atttatttga gaaggctgta gattttattg atgaaaaaag gaaatctata
    13261 gttgcgattt cattatcaac attaggtgta attgctttga taatagtatt tttcttaagt
    13321 agtaacgagt ttagtgtagg aaatgaagct aatgagttgt taaagattat agagaaaaga
    13381 cagtattcta tagctgttga ttactacaca agtatagaaa aaaagttttc tgattcaaaa
    13441 atggaaaggt ttaataagtc tgtttctaaa aaaataaata aattgctatt aaatagtggt
    13501 gataaatatt tagatggaga cataagtcaa gaaagtttta ttggattaat aaataccgtg
    13561 aaagaattaa acaaaataag tatagatgtg gatgacttat tagctcaagc tgatagagtt
    13621 agagaaatgt ataaagaaga aaatactact tatgatattg ccattaacta cataagtact
    13681 gtttcaatat taaatggtat gggtagtaac ctagatgtat acaaacagaa tatagaaaca
    13741 atcaaagagt ctagagatgt ttatgactca gcagtaaaag accaaaaagc atataagtat
    13801 tatgaagcta ttgaaaagta taataaagta ttaaaagaag atgaaaagta ttacagtatg
    13861 gctcaaaatg ggaaagaaca atgtattgaa gaaatgtatg attactatat aagtagagct
    13921 gaagaggcaa atacttctgg agattatgaa agagcattac aatatattga gtatttaaaa
    13981 gacgattatt cagatgatga aaaggtacag agtttagaaa aaaaatataa aaagaattta
    14041 tcattgtata ctttaacatc tgatgacatt ataaatgtaa tagctaaaaa aagtggcaaa
    14101 gacaaggcaa atctatctat aaattcactt ccacaaatga taaaaaataa taaatactat
    14161 tatgctgaag tatatgagta tgataaatta ataaatgaag ttttggtaag tgcaaaaact
    14221 aaagatttat attcatataa agatggtaaa aaagattaca aagtagatta tggtgatgga
    14281 tactttagaa tattagaaga tggaagttat caatttggta ttacaaaaga taaagctaag
    14341 tttgtgttaa ctaatactct tgatgaaaaa gaaaataagt ataaaaagat tgagatatta
    14401 gatatagaga aagcagatag atatgtaaaa agtaaaaaga gtttagaaga attgtttgga
    14461 aaatataaaa atatttatta ttatgctgta gtaaataaag gcttatttag aggcaaagaa
    14521 gtttatgcta ttaatattta caatgaaaaa atatatgcca tatcagaaaa tggactaaat
    14581 gaatattaat taataatatt aaattaatat ataattaaaa agtttttggg gttttaaggc
    14641 gcattatgta gtaatataat aatagggata tataaataat tttattgtaa ggagaagtat
    14701 gggatgagta atgtgaacaa aaagctagtt atagctattg gagctgtagc attagtagta
    14761 ataattttta taggcataat gtgcatgcaa tttaaagggg agaaaatagc aaaaaacaca
    14821 tatgttaatg gagtaaatat tggaaaatta actaaatcac aagcaaaaca ggaattagct
    14881 aaaaaataca aattagagaa tgttgatttt aattacaatg ataaaagctg gaaagtaaag
    14941 agcaaagatt taaatttatc tactgacctg gataaaacag tagaaaacgc atataattta
    15001 aatagaaaga gtgctttctt tggcaatcta tcaaaaacta tttcagcaaa ttttggcaaa
    15061 aaaagcaact tagtagttgc gataaattat gataaaaata aattaaaagc agaaatggaa
    15121 aagatagcta aagaaataga tgtagatgta aaagatgcta cacttgatat aagtggtgaa
    15181 aaagtcaagg ttataccaga ttctgatggt cttaaaatgg atatttctaa gagtatggag
    15241 aattttgata atcaaactaa aaaaggtaac tataaaaatg agttagtagt aaaagctact
    15301 ccagcaaaag taaaaaaaga gcaacttgct aatatagata caaatttagg tacgtattca
    15361 acaacattta aaacttctca aataaataga agtataaaca taaaattagc aacagataat
    15421 ataagtaatg tattacttat gccaggagaa actttctcat ttaataaaca tacagggaaa
    15481 agaagtaagg aaaatggata taaaagtgca cctgtaataa tggaaggtga gatggaagaa
    15541 gattatggtg gaggagtttg tcaagtttca tctacgttat acaattctgt gctatacgca
    15601 ggtttagaaa ttgttaatgt aaaaaatcat actataccat caagttatgt tccaaaagga
    15661 agagatgcaa ctgttgcaga tagtggaata gatttcttat ttaaaaataa tctaaagcat
    15721 ccagtttaca taaaaaatta cgtttcagga aatcaaattg tttgcaatat atatggaagt
    15781 gcagaagata aacaaaatat aacaatatca acaaaattag atggcgtttc acaaactaca
    15841 atgaaaagag ttaatgaccc tacaatgcct aaaggtaaag aaaaagtaga caaaagtgga
    15901 agaaatgcat attctgtatc aacatataga acatttaatg atgcaaatgg taaaaaaatt
    15961 aaaactgaaa aaatagctaa ttcatattat cctaagaagg aaggtattat attagttggg
    16021 actatggaac caaaaccaga ggaaaaacca aatacagacg aaaataagaa taatcaaaat
    16081 acaaacaatc aaaacccaaa taatcaacaa aaaccagaaa caccaccaac tgataataag
    16141 cctaatgaga cacaaccaca accgcaagct taaagttctc aagaatagga tttatgtaga
    16201 gtaataaaaa atataaatct aaataggagg gattactttg aatttaaata atataacgaa
    16261 ttacgttcaa agtatttgcg agaatatttc taatgtcttg gatgtagatg ttactttagt
    16321 tacaaaagat ttaactagga tagcaggtac aggaatattc agaggtaaaa taggagagac
    16381 aatatcagag aagtcagtgt actctcttgt tttaaaagat gggaaatcct atgttataaa
    16441 taaagaaata gaagagaact gtaataaatg tgcaaataga gaaaattgta aagagttagc
    16501 tgatatatgt actcccgtta aaatgggaga gcatatactt ggaatcttgg gtatagctgc
    16561 gtttaatgaa gaacaaaaag aaaagatact ttcaaaagat aaggagttaa ctgcttttgt
    16621 aaggagtatg tctgatttaa tatcttttaa actagatgaa ctttataaac aagaagttaa
    16681 gactatagat gaccttgaga gggaagctat agaaaatgcc ataaagaaat atggaagtaa
    16741 tacagaaggt atgaaaaaag tagctgaggc attaaatata ggtatagcta cactctatag
    16801 aaaagtaaaa aaattcaaca ttaaaagtta atagtattga aaaagaggta acctttttat
    16861 gaaaagaaga ggattacctt ttttattatg agaatggtgg aaaaatatgt atagttttga
    16921 cttgacatat taaatatgtt atcttaaata tatattttag agtggaggtg agtattattt
    16981 tagttaaaga tataaaacaa gacatagaaa gcatgcctag aaaaatttta gatatatctt
    17041 tgatagaaga taataaaagt gatttgactt tttttaatat agaagaagaa gacggtgatg
    17101 aaacattaaa agcattaaaa cagagttatg tgactacaaa ttataaagaa gaaactctat
    17161 taaacttgca aggagcttta aattcaaagt cagatacaac gtctaaggag ttaaaattag
    17221 aatcatataa aagatataac aatgcattgg atttagcata taaaaattat ataactagtg
    17281 ccattaatat ggttaataaa gctctggaga taaatcctaa agacattgat atactaaatc
    17341 ttagaggtct tttaaaatta ttaaaatgtg attttgctaa atcatttgag agtttttata
    17401 ctgctttatg ttatgaaaat aatcatatat ctagaaaata tgtaaatcta atttcatctg
    17461 aagattttaa aactttttta ggaagataca atcattctat aagatttata aatgaagaat
    17521 taaattatga gtcaatacat attttagaga acataattga agaagaacct gaactaatag
    17581 agccatatgt aattttatct ttgttatatg ataaactagg taatgtaaaa aagagagaag
    17641 gatatttaga caaacttaaa gagctagata aagataatcc tgtatttgaa aaaaatgaag
    17701 aagaaaaaga agatacaagt aaaaaggaag aaataaaaaa agtaaaaaga aagaaaagta
    17761 ttttgccata tattatagtt ggctgtgttt taataggtat ggggatatat ttgattcaaa
    17821 gcaaaaagag aatagaaaac ttgaataacc aaataagtag taaagaggaa aagttaagtg
    17881 aaactgataa aaagttagga gaaacgagta aaaaattaga aaaaacgaat aaggaattaa
    17941 atgaggttaa aaataaagaa ccagaaagag agataactgt agctgatgag gaagatttat
    18001 attatcaagc tctaaattta aagaaaaaca aagaatatga aaaagccata gataatttta
    18061 aaagtgtagt ttcttctggt aaaactaaaa aatatatttc tgagtcaata tatcaattag
    18121 caataacaaa taaattatta ggaaataagg atgaagctat aaaatattac aaaaaatata
    18181 taaatactta tactaaaaat gaccagtatt atgatgattc atattacgag ttgggtatgc
    18241 tttattatga taatggcgat ttaaaaaatg cacaacagac tttttatagt ttgagaagtg
    18301 aagttccaga cagtatgtat aacaattcaa aaataaaaga aattttaagt gaaaaatagg
    18361 tttatatagt taagtttttt gaaacaacca agtatgtatt ttattaaatt aaaataaaaa
    18421 taaatttaaa aagagattgt gtcaaattat aactttctat tttaaagaaa gatatttgct
    18481 tgttgataaa actacaaata tatgatttga agcaatctct ttaatttttg gaggtggaaa
    18541 atgaaagttt tcaatcaatt ggtaataatt ttatctatct gggtaatagg agagtatata
    18601 agttccttta tacaaggaat tatacttatt cctgggagta tagttggtat gctattatta
    18661 tttctactac tacaatttaa agttttagac ttgagtagta tagaaaatgt aagtggattt
    18721 ttcctcgata atatggctat attttttatt ccagcaggtg tatcacttat aaagtcatta
    18781 gacctaataa gggaaaatgt attagtgctt ttattagtca tatgtttaag tacactaata
    18841 gtaatgtata ctactggaat tattgtggag aaaatgataa aaaagaagga agaaggacaa
    18901 aaaaatgtat aatgtattac agacaccagt atttggtata atagtaacaa tagttttttt
    18961 caatttagga agatacattc aacgaaaaac aagtaatcct atatgtaacc ctttattaat
    19021 tgcaatcgta ggaataatat tgtttttaag catatctaaa atcccttatg agaattacaa
    19081 gataggagct gatagtctaa atttcttttt aggtcctgtc acagtagtac ttgcagttcc
    19141 actttataaa caatttgaat tatttaaaaa gcatatgttt gagattattg taggaatagg
    19201 ttgtggtata gtgatttctt ttgtatctgt attgataatt ggcaaaatag ctaattcaga
    19261 tgtaagtata ataaattcac taattccaaa atctataaca acaccaatgg gaatatcttt
    19321 agcaaattct ttaaatggtg tagaatcaat aacagttgta gccataattt ttacaggtat
    19381 ttttggtggt atggttgctt ctacagtatt caaactgggg aatataaatc atccagttgc
    19441 taaaggaatt gctcttggaa catctgcaca tgctttagga actacaaagg cttttgaact
    19501 tggagaaata gaaggagcta tgagtggtgt ttctattgga gtctctggta caattacagt
    19561 aatactaatt ccaattataa tgaattttat ataaaaaata aaattaagac gagtaacttg
    19621 aatacttaaa acaaaataaa ataaaaaaaa tttaaaataa aaactgaacg aaaaaaatgc
    19681 aaataatgaa ataaaaaaat catgtactga aattataaaa agaaaaattt catttaggaa
    19741 ttaattataa agagacaatt actaaacttg aatttgctaa aataaaataa attactgcga
    19801 aaatagatat ttagaaaaaa atactataaa tttactatat tgcaagttaa ataataagca
    19861 gtatcatatt atgctagaaa aagtttcatt taaggcataa atgagatgat ttgaacgttt
    19921 ttaaagatta gaatataaaa gattgcacta gacatatatg aaaaagataa tataatagat
    19981 gatgtaatag atgacagttc aagaaattat aaaaaaaatt tatttgaaat attatctatt
    20041 acatcaggaa taatatatgt aagagtaagc ttttaaaatt ctaaagattt agaaagattg
    20101 aagggagaaa gaaatgagtg aagttaagaa taccctacaa aaacatccag ttttaagata
    20161 ttcaacaatg ctatttggga tgttgatgac atctatagga ataaatgggt tcttaagacc
    20221 agcacatcta cttagtggag gtgctacagg tatagcaaca tctataaact atttgacaaa
    20281 tataaatgta ggtttattaa catttttaat caatattcca atatttatct tagggttcat
    20341 ataccttgaa aaagagtttt gtatttcaag tttggtaaat atgattgtat tttcattatt
    20401 attaggagca actcaggaaa taagtaatat tatacctata catgatatat tgcttcaaag
    20461 tgtatatggt ggtatattat ctggtttagg agtcggagtt gtatttagaa ctaggtcttc
    20521 tcaaggtggt acagatataa tagctgcaat actaaaaatt aagaagaata tagaaatgaa
    20581 agacactgct ttagcaataa atggcttgat agtacttaca ggaagttttt tatttgggtt
    20641 ggatttagca ttatacactc ttataggtct atttctaaat gcgtattcaa tgagttttat
    20701 taaagatgca atgaattacc aaaaatctgt tatggtaatg tcaaatgaag tcgatttaat
    20761 agcagaagat ataatgaaga gtttagttag aggtgtaact tttttagatg cagaaggtgc
    20821 atacactcat caaaaaaaga agattatata tacaatagtt tcatcaaatg agataccaaa
    20881 gataaaagat atagctttga agtatgataa aaaggccttt atatctgtaa atgatgttac
    20941 agaagtaaaa ggaagagggt ttaaagcaaa agatttatag aaaattttac aagctgggag
    21001 tttataatgt aaatttgtat attatatctc tcagcttatt taaatttagt atacgaaaat
    21061 aaaggtttta ttaatgattt gtgtatcact ttaaaagata tcattttaaa attaaaattg
    21121 aaaaaattac ttaatatgta gaaaacatga ccactattag gatataataa atttaataga
    21181 tttagtaaaa tatctaggaa taacgttgga ggaatggcat tatgaattta tctaaagaat
    21241 atgttaattt gtatgataat tatttgaaat atataaatga agtaaacaaa gagattagaa
    21301 gtataaagaa catgaagaaa cgtgttttaa aaaggggcga ttttgctcca gaaaatgaag
    21361 tattagaatt ggaaggaaaa acaatacgcg atatagatga tgtcgataca aaaaaaccaa
    21421 aaaataaaat ctataaattt tcaaatgggg atgtatatgt agggaaattc ttagagggaa
    21481 agatggaggg gaaaggctca tatacttttt ttgtagatga aggaacagtt atggagtaca
    21541 taggagaatt taaagaagat aaaaaaaatg gaaaaggaaa ctttatattt tcaaatggaa
    21601 atgaatatat aggttatttt gaggaagata tgatgagcgg tattggaaat atgttatata
    21661 gtagtaaaga tgaatatatt ggaacttgga aaaacggaaa aaaagatgga aaaggtattt
    21721 ataagtggag tgatggatgt atatatgcag gtgaatttaa aggtggaaag atggaagggt
    21781 acggtatttg ctataatagt aaaggggaag tactttatga aggagaatgg aagaataatt
    21841 tgattcatgg taagggaact tatatatggg aaaaaggtaa aaagtatata ggtgaattta
    21901 tgcatggtaa aaaacatggg caaggaactt tttatctaaa taatgaattg gtttatgaag
    21961 ggacttggaa atttgataag ccatctatat ttgatagaac attagatgaa atattttcct
    22021 tgagactgta gctttatcta attagtagat aaagcttttt tctaatactt actgtaaata
    22081 ggtatgaatg atattgatta gtatacacta tcaatattaa cttaataaat gcaatattaa
    22141 aaaattttga ttgattttaa gaaggagaga tatattgaag agattaattg ctttagtgtt
    22201 agtagtactt attgttttat tttatagtcc tgaattatta aaagaaggat atgatttaaa
    22261 agaaaagttt tttcaaagtg aaatatggaa tgaattttta gacaaaataa atataaatga
    22321 taattctaag aaagataaaa aagaaaaaag tcaaaattta caatcaaata atactgaagg
    22381 ggagaactta ggagagtcag atataaagaa ttttgaaaaa ataagcttag gagataattt
    22441 aagctatgtt ttatcaagta tcggcaaacc tggtagaatt gatattagtg aatatggttt
    22501 tgattggtat gtatataatc aatatggaaa agaatttgca atggttggac ttgaaaatga
    22561 tgaagtagta gcactttata gtaattctat taattcatgt gaaaatcaag atataaaact
    22621 aaatcaagat agacaaacag tgagaactaa gattacacca ttaaaatata agagaaaagg
    22681 aaataccaga tatataataa actcagaaaa tcaatatgat ataataagta aggaaggtaa
    22741 gtatattaca attttctacg atattcatga agaaaataga gtttgttcat atttaataat
    22801 tgataaaagc actgaagatg agtttaaaaa tttatatcca gatgatagcg aagaacttaa
    22861 aaaatgtttt gaacttgaag ttatagacct tgtaaatagt gttagaaatc aaagagggtt
    22921 aaactcattg agatacagtg aacaggcaac tttgagttca agaaaacata gtgaagatat
    22981 gagagataat aatttttttg accatgtaaa taagaagaat gaaactccat ttgacagaat
    23041 gaaaagagaa ggtatagtat atacttcagc tggagaaaac atagcagcag gacagattaa
    23101 tgcaatatat gcgcatgaag cttggatgaa ctctgaagga catagaaaaa atattttggg
    23161 gaactataat aatattggag ttggagtaat atttggagga agctataaaa catattacac
    23221 tcaaaatttt tataaataac taaaatattt gaaaggaagt taaaaaatga catcatggaa
    23281 aaaaaagaca gtatataagt gcttaatagc agtagtcttg ttttgtggaa tagtgttaat
    23341 atctaatttt agtaaagttt ctgctttgat gatggatact aatggaaatg ttttgattaa
    23401 acatggttca agggaaaaaa agctaatagc aattaccttt gatgatggtc ctcatcctaa
    23461 agaaactagt caagttttag atgtattaaa gaaatacaat gtaaaagcta ctttttttat
    23521 agctggaaaa catgcaaaat ggtataaaga accattagta agagcaagta aagaaggtca
    23581 cgagatagga aatcatactt tcaatcatcc tgatataagt aatttaagtt ctagtcagat
    23641 agaagaggag attgttaagt gtgaagacat tttgaaagaa gtaactggaa aaaaaccgac
    23701 attatttaga ccaccatttg gaagttatag agaaaaagaa ttaatagaaa ttgcaaaaaa
    23761 gcatgactat aaagttgttt tatggacagg tgtagatgtg aaagattgga aaaatccagg
    23821 agctaatagc attgcagata aaataattaa taaagtacaa aatggagata taatactttt
    23881 gcatgattat gcaactaatg atacagttga agctttagat atgtttattc caaaaatgat
    23941 tgaaaaaggt tttaaatttg taacagtttc tgagttaata aaataatttt taggggggag
    24001 atttacagta tgattcttat gatagacaat tatgattctt ttgtatacaa cctagtccaa
    24061 tatatagaag aattagggga aacagttgta gtaaaaagaa ataatgaaat caaaataagt
    24121 gacattgaag aactaaatcc agaggtaatt gtgttatctc caggaccgtg ttctccaaaa
    24181 gaagctggta tttgcataga tattgttgag cattttaagg ggaaaaaacc tatactagga
    24241 atttgtttag gtcaccaaac tattggacat gtttttggag gagatattat aaaagcacaa
    24301 cagcctgtgc atggaaaagt atatagtatc aaccatacta ataaaggagt ttttagggga
    24361 cttaaaaatc ctttaaatgt cactaggtat cattcactaa tagttgactc caatacagtt
    24421 ccaaaagaat tagaaattac agcaattact gataaagggg aaataatggg gattaggcat
    24481 aagaaatatt taatagaagg agtacagttt catccagaag ctattttgtc agagtatggt
    24541 catgaaatgc ttaaaaattt tataacagaa gctagagaaa gggtacatat gtaatatgat
    24601 aagagagata aatactaaat taaattcttt tgagatattt actattttta gaaatgaaca
    24661 tgacagtttt atattagaca gtgctatgga caaagaaaaa ttgggaagat attcttttat
    24721 aagtagccaa ccatttaagg tattaaagta taaagatact gatgaaaatc ctttagaagt
    24781 tttaaaagaa gaactacata agtatagggt tgtaaatgat actaatcttc catttgtagg
    24841 aggtgctgtg ggatatttat cttatgattt aggtaattac atagaaaatt tacctagaac
    24901 tgctgtagat gatattgaga tgcctgatat gtattttgga ttttataatc atgtaatagt
    24961 tatagaccat cttgtgcaaa aaacttatat agctactcca aacatagata tcgaattaga
    25021 agaaaagata atagatgata tagaacaaag aatattaaaa gaagagaaaa aaggtataga
    25081 tagcatatgt tatgaagaaa aagaagtaac acctataaga cttaaatcta attttacaaa
    25141 ggaagaattt aaaaatgcag ttcaaagtgt tagagagtac ataagacaag gagatatata
    25201 tcaagctaat ttaacacaaa ggttcagtgg agaaacagaa cttacaagct ttgaattgta
    25261 tagggactta agaagattta gcccagcacc atttggggca ttcttaaact ttgaagatgc
    25321 acatatatta tcaaattctc cagaaagatt tataagatgt gttaataaga gaatagaaac
    25381 tagaccaata aaaggtactc gtccaagagg gaaagataaa gaagaagatt taagacttca
    25441 acaagaactt agaaatagtg aaaaagatag agctgaacta cttatgatag tagatttaga
    25501 aagaaatgat attgggagaa tatctaaaac tggaagtgtt aaagttccag agctatttgt
    25561 aattgaacca tatgcaaatg taaatcactt agtttccaca gttgtaggtg agttaaaaga
    25621 tgataaagat gctactgatg taataaaagc aacttttcca ggggggtcta taacaggagc
    25681 acctaagatt agagcaatgg aaattataga cgaattagag ccaacgcaaa gaaatgtata
    25741 tactggttca ataggttata taggttttaa tggtgatatg gattttaata tagcaattag
    25801 aacaataatc aaaaatgaca aaaaagtcta ttttcaagtt ggaggaggaa tgacttggga
    25861 ttctgaccca gatgaagaat atcaagaaac acttgataaa gctaaatcca taatgaaggc
    25921 tttgagggga tattatgaag aataatgtag gttttgatag tagtttaagt aaatttggaa
    25981 ttggtttgtt tgaaactatt agagttaaaa atggaatagc agtagattta gatatccata
    26041 tagaaagaat gctaagttca ataaattgtt tggatttaga tataaaatat aaaaaagatt
    26101 tcttgataaa tgaaattgtt acatatataa aaaaagaaaa tgtcattaat aaagcactta
    26161 gaattactgt ttttgatgaa ggttataata tatctattag ggatattcca tataatcaag
    26221 agacgtatga gaaggggttt aaattagcta tatctccaat agttaggggg aatagtttaa
    26281 ttcatagaca taagactact aattattttg aaaacatata taccaaaaat atcgcaaata
    26341 agactggtta taatgatggt atatttttaa attcagaagg tgtaatatta gaatgttcta
    26401 tgagcaatat tttctttgta aaaggagaaa gagtgtacac tcctagtgat agattaccga
    26461 tattaaatgg aataataaaa aaaaggatta tagagatttg tgacgaatta catatagagt
    26521 tgatagaaaa tgaaattaat atatcagaaa ttagtagttt tgattttgtt tttgtcacaa
    26581 atagtcttat gggcgctata aaggttacag aaattgacaa aataaaattt aataaagaaa
    26641 atgttgtttt tgataaaata gtgaagttat tagaataaat taaaatatta acaatttgtt
    26701 ggagacaaaa gatgataggt tgtatttatg aagtatacaa tgaagagata actaaaataa
    26761 tagaaaacca aaacactttg gctgtatatt tagtgggttc tagtaaagac gtagatttta
    26821 ctctttatga tgtagagata aacgatattg atgtgttcgt ttttgtaaaa gaaggggaaa
    26881 aacaagagag aatactgttt aaaaaaaagg gaatagaatt tgatgtaaat tacttttcaa
    26941 aagatggtgt aaaaaaatta ttatcaaata gggaatattt ctttgtgaaa gaaatgaaag
    27001 atgctaaagt actgtttgat agggagaata tatcacatat tataaaagat ataagtagaa
    27061 atatttactt agaaggaccc agtaaaatgt cattagagga aaagtctttt ataaagcaag
    27121 atattggagc aaaaatatcg aatttaaaaa ataaagaaaa atttgatgtt tttgaatatc
    27181 attttttgac gaatttatat ttaaaagata taataattgg gtactttaat ataaatgata
    27241 aatgggtacc aaaagacaaa aaattgctaa aagttttaaa aaaagaaaat aatgagcttt
    27301 ttgaactagt gtcaaaagta agtgaaaatt atgactatca aagactttta gatgtttata
    27361 attatatttt taaagaaatt gagacaaaag aggttataaa actaatcttc tagtcacaaa
    27421 tcaatggggg gagtttaaat gaataaagtt gataaagaaa agatacaaca tgcagtaaga
    27481 gaaatactag aggcaattgg ggaagaccca gatagagaag gtctaatcga aactccaaat
    27541 agagttgcta ggatgtatga agagatattc tctggtctta gtgaagaacc aagagaccat
    27601 ttaaaagttc tttttgcaga tgaaaaacat gaagagttag tattggtaaa agatattcca
    27661 ttttattcat gttgtgagca tcatctagtt cctttctttg gaaaagctca tattgcttat
    27721 ttaccaaaag gaggaagact tacagggctt tctaaacttg ctagagtaat agatacattg
    27781 gcaaaaagac cacaattaca agaaagaatc actaaaaatg ctgcagatat aataatggaa
    27841 gaattacaac cttatggtgt cttagtagta gtagaagctg aacatatgtg catgacaatg
    27901 agaggcgtaa aaaaaccagg ttcaaaaact gttacatcag cagtgagagg aatatttgaa
    27961 aaggacattg cgtctagagc cgaggctatg agtttgatta ctatgaagta gcaatttatt
    28021 atagatataa tcatttattg agataaaatt taatttaagg gagtgtcatt aattgtgttt
    28081 gattatggta aaagaactta tataatggga atattaaatg taactccaga tagtttttct
    28141 gatggaggag attttaataa cttggacata gcaatacaac atgcaaaaga tatggttgac
    28201 caaggtgcag atataataga cctaggagga gagtctacac gcccaggtca tagctatgta
    28261 gactcagacg aagagctaag aagagtaatc cctgtaataa aaaaacttaa acaggaattg
    28321 gatataccaa tatcaataga cacttataag gcagatgttg cagaagaagc attaaaatta
    28381 ggtgtcacta tggtaaatga tgtttggggt cttagaaaag ataaaaatat ggcttctgta
    28441 ataggaaaat atgatgcaga agtgtgtata atgcataatc aagatgggac aaactatgac
    28501 aaagatataa tggagtcaat aaaagacttt tttaaggtaa gtatagaaat ggcaatgagt
    28561 tgtggtgtaa aaaaagaaaa aatagtactt gacccaggtg taggatttgg caaggatttt
    28621 gaacaaaata ttgaagtatt gagaagatta aatgaattaa aagatttagg gtatcctatt
    28681 ttgcttggga catccagaaa atcagtaata ggaaaagtac ttccagttga gcctaaaaaa
    28741 agattagaag gtacaatagc tactactgtt cttggtataa gagatggcgt agatatagtt
    28801 agagtacatg atgtttatga aaatttaatg gcagctagaa tgactgatgc aatatataga
    28861 aagtaggtat aatataatgg ataaaatatt acttagtaat ctaggattct atggatatca
    28921 tggtgttctt aaagaagaaa attttctagg tcagaaattc tttgtcgaca tggaacttta
    28981 tattgattca agagaagcag gtcttagtga cgatataaat aaatctgtaa gctatgccga
    29041 ggtttacaat gttgttaaag atattactga aaataaacaa tttaatcttt tggaggcttt
    29101 agcggaaaat attgctgaag aagtcttgaa taaatttata cttataaatg gagttatggt
    29161 cagagttaga aagcctgagg ctcctgtaaa tggtatttat gactattttg gtgttgagat
    29221 aaggagaaca agagatgaat aaggcttatt tgggaatagg tactaacatg ggtgatagat
    29281 ttgataattt atcaagagca tgtgaacttt tgaaaaatag tgattctata tataaagtaa
    29341 aagaatcaag cttatacgaa acaaaaccat ggggatatac agaacaagca gattttctaa
    29401 atatgtgtgt agaaatagaa acagagtttg aaccttatga gttgttagaa tattgtcaag
    29461 aaatagagag agaactacac agagagagaa tagttcattg gggaccaaga actatagatg
    29521 tagacgtact attttttaat gatgtagttt ccactgatga aagactaaca atacctcatc
    29581 caaggattca agatagagct ttcgttttga taccacttat ggatttaaat gaagaactta
    29641 taataaatga aaaaacaata aaagaacatt taaacctcct atctgctgaa gaaagagaag
    29701 aagtaaagga gcttgtaggt tatgaaagaa aacctattta ataataattc aaagatagag
    29761 ataaatacaa ataacaaaaa gataactgta aaaaaagata aacttataat agctggacca
    29821 tgcgcaatag agagttatga gcaacttttg gagactgcta aatttgtaaa aagtcaagga
    29881 gcaaacattt taagaggtgg agcatacaag ccaagaacat cgccaaattc atttcaagga
    29941 ttaaaaaaag aaggtcttga aatattaaaa gcagttaaag acgaagttgg tatggctgtt
    30001 attacagaac ttatggatgt aagagatatg gacgaactgt atagtataag tgatataatt
    30061 caaattgggt caagaaatat gcaaaacttt actcttttaa gtgaagtggg aaaacaaaat
    30121 aaacctgtta tgttaaaaag aggaatagca tccacaatta ctgaatggat aggtgcttct
    30181 gaatatatag caatagaagg aaatagtaat attataatgt gtgagagagg tataagaacg
    30241 tataatgatt atactagaaa tacattagat ttagctgcgg tacccattat tcaaaaggaa
    30301 acaggtcttc ctgttgtggt agacccaagc catgccactg gagttagata tttggtaaaa
    30361 cctatgtcac tggcatcttt tgcatgtgga gcagatggaa taatggtaga agtacatcct
    30421 gacccagaaa atgctttgtc agatggtgct caatctcttt gctttaatga atttgaagat
    30481 ttaatgaaat caattaataa ttattaaaag aggcaagagc ctctttttta ttcgtaatcg
    30541 ttgctaaggt aaatttataa gttataattt gatagttaga ttatttaata taaataaaga
    30601 tttaatattg atagaattaa tataaaaaat aaaaattttt tgattaataa gaaggatatc
    30661 aataaaaaaa gtcgaattgt gtatattgag tgattgacaa atttagaata tagtgtagaa
    30721 tagaaatgtt aacacaaaaa attacaccag aaggtgataa tatgaatgat ataaaagaca
    30781 ttattgaaga aataaaagct agatgcgata tagcaagtat aatatctgaa tatatgaata
    30841 taaaacaatc tggagctaat tacaaaggat tatgtccatt tcatggcgaa aagacacctt
    30901 ctttttatat aaatacatca aaacagattt ataagtgttt tggttgtggt gaaggtggag
    30961 acgtaataaa ttttgtcatg aaaatggaaa atttggattt tatggatgct gtaaaaattt
    31021 tagcaaataa atgcggtata gaaattaaca ctaacatgaa tgaagaaact aggattaaaa
    31081 tagaaaaatc taagaaattt caagatattc atacggaagc agctagattt tatctttcaa
    31141 acttattggg aagcaaaaat cttgggtatg aatatttaag aataagagga ctagatgata
    31201 aaattattaa gaaatttggt ttaggatttt ctttggattc atggaattca cttatgaata
    31261 ctctaatcag taaaggatat aaaaaacaag acttattaga gtgcggtcta attgcaaaaa
    31321 atagagatgg aactaattgc tatgataaat ttagaaatag agttatgttt cctatattcg
    31381 attatagagg aaatataata ggatttgggg gaagagtatt agacgattct ttgccaaaat
    31441 acttaaattc tccagacaca ttaattttta ataaaaaaca gaacttatac ggattaaatt
    31501 ttgctagaaa aaatttagaa agtaaaacta tagtcttagt tgaaggatat atggatttaa
    31561 tttcacttta tcagtatggt ataaaaaatg tagtagcaac ccttggaaca gccttgactg
    31621 aacaacaagg cattttaata aagagatatg cggacactgc tattatatct tatgattctg
    31681 atgaagcagg aataaaagcg actttaagag ctatagatat acttactaaa ttaggtatca
    31741 atgtaaaagt gttagactta aaagatgcta aagacccaga tgaatttgta agaaaatacg
    31801 gacttagtga ttataaaaaa gctatggatg tttctactca ctacataaaa tataaaatag
    31861 atcatcttaa aaaagaattt aacattcaaa aagatgaaga acgagtgaag ttcgcaaaag
    31921 aagcttctaa aattataaaa caattgacaa gtcctgttga aattgatttt tatacaaagt
    31981 atttaagcaa tcaaatagat attaatgtcg agtctataaa gagagaagtt tatggtaaaa
    32041 attacaataa gccatataat aacaaaaatc aaaagaaaat agaagaaaaa gtaattgaaa
    32101 aagtcgaagt cagacaagac ggaaaacaat tagttgaaga aactctaata aaaataatgt
    32161 tagaagacaa aaaaattaga gaaatagcgt tacttaaagt agaagaaagt gattttttat
    32221 tgaaagaaag taaagaaatt ttaaattaca tgattaaaaa tcaagaattg gacaaaataa
    32281 ctattgacaa attgaaaagt ttaaacatat ccgaagaata cttaaaagaa ttaaattcaa
    32341 tttctttgaa tagtataaac ttagagaaca caaaagaaat agaaggaata ataacaaata
    32401 tcagaaaaaa ctcattagaa gagcaaatta atagcttgtt gagagaacaa caagaattag
    32461 aaaataataa tgatatgaaa gaggtagatg gtagagttat ggaaattgct ttaaaaatag
    32521 ttgagataaa taaaatttta aagagcttgt agagaaagga ggtttgagtg tggaaaataa
    32581 atcgaataaa aaagagttaa aaaaggttac tgctaagaca ttaatagaaa aaggaaaaaa
    32641 gcaaggttct ctgacacttg cagagataat ggaagctttt tcggagactg aacttgataa
    32701 ggatcaagta gaaaatcttt atgagacttt aggaaatttg ggaatagaaa taacagaaac
    32761 aaaaaactat aaagctgata tagatttttc ggttgctgat gacgatttaa gtataggcca
    32821 cttagatgaa gatgcagagg caatttcaca tgatgactct tctgcaatag aaatagaaac
    32881 tgtggattta tctttaccaa aagggataag tatagatgac cctgtaagaa tgtacttaaa
    32941 agaaatagga aaaattcctc tacttaaacc acatgaagaa gtagaatttg ctagaaggat
    33001 gcacgaaggt gatgagatag caaaacaaag gttagttgaa gcaaacttaa gactagttgt
    33061 aagtatagca aaaagatatg taggaagagg tatgcttttc ttggatttaa tacaagaggg
    33121 aaatttaggt cttataaaag cagtcgaaaa atttgactat acaaaaggat ataagtttag
    33181 tacttatgca acatggtgga taagacaagc tataacacgt gctattgcag accaagctag
    33241 aactataaga ataccagttc atatggtaga gactataaat aagctaataa gagtatcaag
    33301 acaactactt caagaacttg gaagagatcc aaaaccagaa gaaattgcaa aagaaatgga
    33361 aatgacagaa gataaagtaa gagaaataat gaaaatagct caagaccctg tgtctttaga
    33421 aacaccaata ggagaagaag aagatagcca tttaggtgac tttattccag atgatgatgc
    33481 tccagcccca gcagaggcag cagcatattc tttattaaaa gaacaaatag aagatgtact
    33541 tggttcatta aatgatagag aacaaaaagt attaaagctt agatttggtc ttgaggatgg
    33601 tagagccaga actcttgagg aagttggaaa agagtttgat gtaactagag agagaataag
    33661 acagatagaa gcaaaagcac taagaaaact aagacatcca agtagatcaa aaaaacttag
    33721 agattattta gactaaaaag atacatcatt gatgtttttg tgataaatgc catgagataa
    33781 gtgatatctc atggctattt tgtagtaaag atttaatttt atttttgtag ttatttcagt
    33841 ctaatatcta taacttggat taaatcctat aaataaaggg aattgaaagg agaattatat
    33901 ttgaaattaa cagatagatt attgaaaata gcatcattag tgtcagatgg taaaaaaata
    33961 gctgatatag gaacggacca cggatacata ccagtatatt tgttaaaaga gggaaaagta
    34021 ccatttgcag tgctagcgga tgttaataaa ggacctcttg acaatgcaca taaagaagtc
    34081 atacagaaca atcttttaga taaagttgat ttacgattgg gttctggtat agagatactt
    34141 gaaatagggg aagtagaaga agtgataatt gctggtatgg gtggaatctt gataagtgag
    34201 cttctcgaag ctaaaaaaga agtagcacat aatgtagaaa aattaatatt acagccaatg
    34261 caagcacaag aagaacttag atattacctt ttaaacaacg gatatgaaat tttagaagaa
    34321 gttttagtga gagaagattt tagaatatat gagataattg ttgccaaata tacaggtaaa
    34381 aatactataa tagaagatga gatatattat gaggttggaa taaagctttt agaaaacaaa
    34441 gattctcttt ttaatgattt tatagaaaaa aagataaaga catatagttc tatagttaat
    34501 aaattagaag ggaaaaatgg ggaagctata gataagaaga gaaaggaaag cgaagttgca
    34561 ataaaaaaac ttgaaaattt aataaaataa ataggaggta tatatgctat taaagagtct
    34621 aactagaaaa attgaaaaaa agtatcctct aaacttagca gaggattggg ataatgtagg
    34681 tcttatagtt ggagattttg atatggatgt aaaaaaggta ttggtatctt tagaagctaa
    34741 tgaagatgtt attgatgaag ctatatccaa aaatatagat ttaattgtga cacatcatcc
    34801 ttttatattt gggaaaatta ataaaattaa tagtggagat ttaaaaggca gacttatcca
    34861 aaaacttatt aaaaatgata tatcacttta ttctatgcat acgaattttg atatagcatt
    34921 tgatggtcta aatgactatt ttatggaaat tatggaattt ggtaattcaa aggttttaga
    34981 tataactaaa agcgaaaatt tgtataaatt agcagtatac gttccacata actattcaga
    35041 tgaacttaga aaggttttaa gtaattcagg agcaggtcat atagggaatt atagtgattg
    35101 tacgttttca acagaaggtg aaggacaatt taagccatta gaaggctcta atccgtttct
    35161 tggaagtgta aatgatatag aaactgtaaa tgaagttaaa attgaaactg tagtaccaca
    35221 gaagctttta ggtggggtaa taagttctat gttagatgca catccttatg aagaagttgc
    35281 atatgatttg tacaagttag aaaataaagg tgagatattt ggactaggta gaataagtaa
    35341 acttgataaa agtatgacat tagaaagtct ttcaaggaaa ataaaagaga aattaaatat
    35401 gaaacacata agagtagttg gaaaccttag tacagacata acgaaagtag ccgttgtaac
    35461 aggagctggt tcagaatttg taaaaaaagc taagagacaa ggtgcagaag tactaattac
    35521 gggtgatgta aagtatcatg aggcacaaga tgcacttgat attggaatgt gtatagtgga
    35581 ttgtggtcat tttgatacag aagatatatt caaaaatgtt atgaagagat ttttagatga
    35641 atttagtgaa attgaagtaa taaagagtaa tgtatatttg aatccattta gtactattta
    35701 gcagtgtttg ataataaaaa tactatataa aaaataaatt tgagtttaat tagggggata
    35761 atgatgaaag tagcagtaat ttttcatagt gtttgtggga gtacatattt attagctaga
    35821 gaatataaag aagcgcttga agaaatgaat atcgaggtag atatatttag agtaagtgac
    35881 gaagttgcaa aaacacttcc tcaatattat ttgataaatt ccaaagaata caaagacgaa
    35941 tttgaaagta taaatgtaat taaatctgga aaagaaatat tagattatga tgctatattt
    36001 atgggttcac caacatatta tggaaatgta tctggaccaa tgaagatgtt tatggatagt
    36061 ttttctgata tttgggtagg tgctcctttg agtggtaaaa tatttggttg ttttgctaca
    36121 gcaggttcac aacatggagg aggagaatta gctttgcaag ctatgaatat atttgcccaa
    36181 catatgggaa tgactctttt gtcagttcca tgttcagtaa gaggaggtta tccagcgtat
    36241 ggaatacttc atatagcagg agataattct gatataaggc caaatgatga tgccaagata
    36301 ggtataagag attacctaaa aagacttaac atataagaat atcatataaa aatacctaaa
    36361 agcgactgta tatactttta ggtattttta cttaattata aacgtgaagc tttaccagaa
    36421 atatggtcaa tttctatttt aacaacagtt gttaagttca tatccttctc tatgtacttc
    36481 atgccttctt caaagaatcc tttagaatat ttttttatta tttctacaag agcatttttc
    36541 ttttcttcat tttctacagt gcaagctttt ccaaaaacta tagcactaga ataagtagta
    36601 ctaaatttat ctggaataac actttcatta gcaactacta aaaaagaaac tttgttgttt
    36661 ttcgatatat tatctaactt atgcccattt cttgcacaat gaaagtaaat agaatcatta
    36721 aagtatacat aatttacagc aactccataa ggataaccat tttcagatat agtggaaaaa
    36781 gtaccaaatt caccattttt taatacttca acagtatctt cttttgtcat ttctcttttt
    36841 ttcaatctca tttctttaaa cataatatca tcctttctaa ttttgatgct taaattaaat
    36901 tttagaacat ttataaagat tatgctatgt tttttacaaa ttttaagaaa aaaatatagt
    36961 ttaagataaa aggtagtgaa agagaagcta tttggaggtt tatttatgat attattgtta
    37021 gagtagtaca aataatacta ataaatttaa tagctggttt cttgttattt aaggtagtaa
    37081 gcatgtctat aagaagggga agttatcgag ggtagaagtt gttgtttata acgatattat
    37141 aaagaaaata ttattatata aaataataaa tagtaaagag gtatcaagtt gaatataata
    37201 cttaatacct cttcaaaatt aagttataaa agtgttgtgg gaattgtcct atacatggta
    37261 aggagataat aaagaatgta tctttaaagt ctcaactaaa cagcaaaatt tatccaacaa
    37321 acatacaata aatgcttctt tgtatctagg tggcttaaca gtaagtggcc acatgtgttt
    37381 taaaattatg tccgtttctt tttcatttat ttgaaaaaat aaagttgcat tttttaatgc
    37441 ttctctaggg tgagtaaatc catgtaatcc ttttctatca cctttgtaat gccaatcata
    37501 aagaaaaaag tcgtgtagta aagctcctct aataacactt tgaatatcaa cacttaagtg
    37561 caatttttta cataatagat aactataata tgctactgac aaactatgtt caagacatga
    37621 aacattgcca tgatgaggaa atgttctcat aagttgaact ttttcagaag aaagtatctc
    37681 agaagcacat tcattaaaat atttgatttc agcttttgac aacattatga aaatctccat
    37741 tcttagtaat atataaatac tatacttcaa cgataatatg aaatatttct tatcctacaa
    37801 aatataatac ccaataatac aagtaagata ccttttatgg tattttaaag taagagagat
    37861 tttattaggc taaacaatga aaaaattaaa agtaaagcta tagcaatata tagtattttt
    37921 ccaagaggat tgccaaaatt tatagtccat ccaataccaa accttttatt aaccattaat
    37981 gatgggtcat ttggattatt atacatgatg cctgctatcc aatacttctc atcttcttct
    38041 ggagaataag atgagttgaa ttttaaattt ggggaattaa tatatgttgc tattaaataa
    38101 attataacta aaagcgttgt aatattcata gcagttaata gttttgtttt tattgataaa
    38161 agagtagtaa aaaactgtgt tgtcattata atcatcaata ttaaaaacaa ataaccaatt
    38221 ttatttaaat atttaatgtt ttcaactcta ctttcttcaa ttctatttgt atctatctta
    38281 atccttgact ttatggatcc aatggaagtt atatataata aaaccattaa acaaaagtca
    38341 gtaccgatta atttaaatac attaagaaat gatttatcta taaaaacatc aggagaccca
    38401 tttatgttcc aatgagtggc aattgagtct ggcaattgat tataattaaa tgctataaaa
    38461 atactcattc ccaaagtaaa tagtatcggt attaaataga ttattttaaa tttttttatt
    38521 attttatttt tcttatttat aaaatccata tctactatta attttgaatc tatatctata
    38581 tgacctaatt tagcataaat ttctgattta agcttcttag cttttttatg tgtatgaata
    38641 tatagtatac tttcatataa taaaaaacct ataataccaa taaaatagga aagttccaat
    38701 ttattaaatg taaagaccag aataaaaact aatataaagt ctataataaa acctaaagat
    38761 aatagttttt taaattcttt atctaacttt ataaagtaat tataattttt atgctcttgg
    38821 tctatagaaa ctccatagat gtgtttttta cctacaaaat agggtataaa ataaaatgta
    38881 gcatacatca aaattagaac tggaaatatt gtaaatagac attcaatctt actcataata
    38941 tttcacctca tacttgtcaa ataaacttga acttagtgac aaaaattctt ctttactaat
    39001 acctgataaa taagattttg ccaccaataa ttccaagtca agtttatttt tttgacgagt
    39061 tgtattatct attttcattg gtagttgagc tacaatagca ccttttcttc tatcaatatt
    39121 taagaatccc tcttctttta attcattgta ggatttgttc actgtatgta aatttacacc
    39181 aatattttca gccatacttc ttacagatgg aagtgattca tttattttca attctcctga
    39241 agctatagcc ttagttattt cttctttaat ttgtacataa atagatttat cactattaaa
    39301 atctaaattt aaaaccataa aaaacctcca ttatgcttta taaatgaaaa cgattgttat
    39361 atacatagta taacataaaa aataataaca aacacaaaat ataagtttat attttgtaaa
    39421 aattgtaatt taaaaaataa cataattttt attaaaataa tacagatact atttatagat
    39481 agaaataaaa attagaaagg agaaaaaata tgttaacata tttaatgaaa agacaaatgc
    39541 ataaaaaaga tgatggaatg agtaaaccaa tgatgattac aggagctgta attacaggtg
    39601 taggagcata tgctgtatat aaaatggtaa aaagccataa atctaattct caaatggtca
    39661 atacaaatta ttatggaaat agcgattatg atgattataa atatgacgaa tttgattatg
    39721 actgtgattg tagagacaca aaacaagatt atgaatatga agaattaaaa aaaaaagtaa
    39781 aagaatttaa ttcaagaaga ataaattgtg aaaattgtcc acatgtttct caagaagaaa
    39841 tgatgcaata tgtaaatagt gttaaagatg taaaggaaga gcttgattta catgaagatg
    39901 ctaaaaaaga taatatttac aaagaagatg aatacaaaaa atatgaagaa gaataagtaa
    39961 tattttgtat aactgaacaa atagtaatgt caaattattt aatatctagt tttaatatgt
    40021 aagttgtaac ttaacttgaa agaatcagta tcattcttta gatagttaag taacaactta
    40081 cattttattt ttataaattt taatagttct ttgtgactat tttgtaattt tagaaatatt
    40141 ttagtatcca gggtaattgt gtataataaa acttgtatag atagatagta tgaaattaag
    40201 cagatagttt aaaattaaaa tgaaaagaaa ggaaatagtt atgttaaagt tgttgatagt
    40261 tgaagatgat agtactatat cttttggaat aaagtatgct ttagaacaag aaggatttag
    40321 tatagatata tcaaaggatt tatctagtgg aaaagaaatg atttcttcta atgaatatag
    40381 catgatactg ttggatgtta cattgccaga tggaactggt tatgagcttt gtcaatatat
    40441 aagaggattc tctcaggttc ctataatatt cttgactgct tgtgatgaag aagtaaatat
    40501 tgtaatgggt ctcgatatag gtggagatga ttatataaca aaacctttta gaattagaga
    40561 attaatatcc agaataaaag ctgttttaag aagaaaaggt aatacttcag aagaaaataa
    40621 gaaaatactt aaatttggag atttaagtat atatacatta gaagctagag tatataaaaa
    40681 tgataaagaa atatttctga catcagttga atataaactt cttttaattc ttatacagaa
    40741 taaaaatact gttttaagta gaactcaaat attggaaaaa ctttgggatg taacttatga
    40801 ttttgtaaac gacaatactc taactgttta tataaaaagg cttagagaaa aaataggtga
    40861 tgatttatgt gaaccaatct acatagaaac tgtaaggggg attggttata aatggatagg
    40921 aagtgaaaat agtgtttcta tataatccag aagtgaagaa gtttttaagt aagtatgtta
    40981 ctttgatgtt tattgttatc ataatatcta ttggatttag cataatcaac gtgtccttaa
    41041 ctaaagagat ggttgtaaga aataatcagg ctataatagg aactttatca agcaagtatc
    41101 caaacttaga aagtcagata gtagacataa taactcaagg gaagtctatg gagaacatag
    41161 attatggtca gaaaatatta attaagtata attatgataa atctattagg ataaactctg
    41221 agcctattat ttctaaatta gttttagaga ctatcaaaat aaatataata ttagtatgta
    41281 taatatttat tttgatattt gtgttgattg ttagatattt tacgtcaatt tacaatgatt
    41341 tatcagatat gactaagtat gtttactata gttcagaggg taagccattt gatatgaaaa
    41401 acaagaatca agaagggcag ataggtcttc taaaaactga actcttaaaa atgacgacaa
    41461 ttcttaatga aaaggttgaa cttttaaaaa gagaaaagat atttttaaac aatacaattt
    41521 ccgatatatc acatcaatta aaaactccta tgacttcttt aataatgttg aatgatttat
    41581 tatataatga tgtaccatac gaagtaaaaa tcgatttttt aaataagata aaaaatcaat
    41641 taaatagaat ggattggttg attaaaagca tgcttaaatt atcaaaggta gaagcaaaag
    41701 tgataaattt taaaaaagat aaggtaaaat ttagtgaact catacataga gcaatgctat
    41761 ctatgaaaat acctatggag attaaaaatc aaaaactgac tatagaggga aatgataatg
    41821 tatcttatat tggtgatatt gattggtccg tggaagcatt agtgaatata atcaaaaatt
    41881 gtgtagaaca tactcctgaa tttggaaata taattataac ctataaagaa aatccattat
    41941 tttctgaact aataataaaa gatgagggtg aaggtataga taaaaaagat ataccacatg
    42001 tatttaaacg attctataga ggaagaagta gttcaaaaga agatagtgta ggaataggtc
    42061 ttgcaatgtc aaaatctata atagaaagcc aaaatggcga tatatatgta aacagcgaaa
    42121 aaggtaaggg tacagaattt catataatat ttcataaaat gtatgatagt gactaatctg
    42181 taatatttaa ttcactttat agtaatagcc aaaacctaat atatgaagta tagaatataa
    42241 atattggagg tagttatgga aattttaaga gtagaaaatc taactaaaag ttatggtaaa
    42301 aatgaaacaa aagttgatgc tataaaaaat gtaagtttat cagttgaaaa aggaacgttt
    42361 atagcaataa caggtccaag tggaagtggt aaaagtacct tattacattt attaggagga
    42421 gttgacagac caactagtgg taaggtttat ataaatgatg ttgatatata taatttaaaa
    42481 actaaggatt tggcgatatt tagaagaaga aatataggtc ttatatatca attttacaac
    42541 ttaattccag tcttaaatgt gaaggaaaac atattgcttc cagcagagct tgacaataga
    42601 gatattgata gagaatattt tgatgattta atgaaaacat taggtctaat tgatagagaa
    42661 aagcaccttc caaaccaagt atcaggaggt caacaacaga gaacctctat aggacgtgca
    42721 ttaattaata gaccttctat aatattagca gatgagccaa caggtaattt agatagtaaa
    42781 aattcaaagg aaatattaga attgttaaaa ttgtcagtaa aaaaatacaa ccagacacta
    42841 ataatgataa ctcatgacaa aaatatggca cttcaagctg atagaattat aagcatagaa
    42901 gatggaatca taaaaagtga tgaggtgatg tagatgaatt tatatacatc actaactatt
    42961 agatacttaa aacaaaataa aagaagaacc attgtaacca taatcggtat aatactttca
    43021 acagctttaa tttgtggtat aggaaatata tttgaaagtt ttatggatta tcaaatgaga
    43081 gaaactataa agaatgatgg aagtttccat gttacatttt atgatgtaaa tagaaaaaat
    43141 gtggaatatg taacgaaatc agctgaaata gaaaaacatg catttaccaa acaacttgga
    43201 tattctaaat tagaaaatag tgaaaatgct atattaagta taaagcaata tgataaaaat
    43261 gcaataaatg gatataaagt ttctataaaa gaaggtagat ttccagctaa ggaaggagaa
    43321 attgttttaa gtgaaagtat tattaatctt atagatgata agttaaaaat aggagataag
    43381 ataactttaa aagtagggga tatgtttgac tcaagcaaga aaaagattga tagtatgaca
    43441 tttcatgaag gtgattatat agcaaatgaa aaagatagaa cttttaaagt tgttggtata
    43501 attgaaaaac ctgggtttga acgttataat ggaattgcaa cagctatagc ctactttaat
    43561 cctatgaata attacaatga tacaattaat gtatcagtag cagtaaaaaa tcctaaagat
    43621 gtgtataaga taagtaataa aataagtaaa aatatatatt caaataaaga taaagaagca
    43681 gtttctgata tgataaaata caatgaacat ttattgaggt tacaaggtgc tagtaagtat
    43741 tcaaatataa atagctctat aaagtctata attatagcag taactatttt agtaatcgta
    43801 tgtacaattg ctacagtgta caattccttt agtatttcta taaatgaacg aaaaaaacag
    43861 tttgggatat taaattctat aggtgctaca tctagtcaaa ttaaaagatt agtttttata
    43921 gaaggtatta taattagttt aattggtata ccaataggac taatatctgg aacagtagct
    43981 atagacttat tgtttaaaat tataaataag tattttactg aatcggttgt tactaagatg
    44041 agtttgcaga tagtgtataa tccaataata attattgtta gtataataat agttttgctt
    44101 acaatcttta tatcaattct actacctgca atatcggctt ctaatatttc tccccttaat
    44161 gtgattaaaa atactggaga gtataaagtg ggcaaaatca aaagctcaag acttattaaa
    44221 atgattttta aaactgaagg agtacttgca tataaaaata ttaggagaaa tagaaaaaaa
    44281 tttataataa ctcttttttc tttaatggta agtataataa tatttatatc ttttagtggc
    44341 tttacattac ttttactaag aggtgaagaa attagaaatt ctcaaagaaa atatgatttg
    44401 tatttaactg caaagaacac agctaggtct gtagaggata ctataagtga actagaagat
    44461 attgatggga taaaaaactt tgaattggca acaggacaat atgtgtctat aagagtaagt
    44521 gaaaataaaa taaataaatc caaggaagat ttaatcagga aatattatca aaaatataag
    44581 attggagata gttatgaata tgatttcagt aataatgaat taatttttcc aggagatttt
    44641 gcagtaaaaa acaaaataaa taacttagta cagggctctt ttaataaaga gagagcaatt
    44701 gaagaaaatg gtgttatatt agttagaaaa agtgcaattg aagaaaatgg gaagaaaggt
    44761 gtagtagaac ttaccaacta taaagtagga gatacagtaa attgtgaata tcttgatgaa
    44821 aatgccttaa gtaaaaaagt aaaggtcaag attcttgcta taactgacga agaacgtcta
    44881 ggtcttggtt atcaaaatat ggggttacaa tttataactt atgatgaagt tgctaaaaat
    44941 ttaaatttaa aattaagtaa aagccttata tttattgatt caggaggaag cattaagact
    45001 aagaaggaaa tagaagcttt ggcaaataaa aataatttta acttttatga tgaaagtgca
    45061 agcaatgaaa gtgaaaaaca agatttaaag gttattaaaa tatttgtata tggttttata
    45121 gtagtgatat ctttagtgag tgttacaaat attctaaata cagtaagtac aagtataaat
    45181 ctaagaaaaa gagaacttgc agtaatacaa tctatagggg ttactcctaa aggatttagg
    45241 aaaatgatat atttagaaag ttttatatat ggtatactgt cattgttgtt tggaatacca
    45301 attagtattg gtataattct aattatgaat aaacttattt caggtgtaat tgaattttct
    45361 ccgattatac cgtggacagc catagttatc tgtatagtaa gtgtttttat aataactttt
    45421 atagcagggt atataccaat gagtaaatta aataaagaaa atataataga taatataaga
    45481 agagaaagta tatagatata aaaataattc ttaactatat aaaatattat taaaatcatt
    45541 taagtgg
//
LOCUS       DAMJWC010000029        44927 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMJWC010000029 DAMJWC010000000
VERSION     DAMJWC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44927
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.029"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            78..1790
                     /gene="ptsP"
                     /locus_tag="PC503_001831"
     CDS             78..1790
                     /gene="ptsP"
                     /locus_tag="PC503_001831"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF2527804.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(2582..3247)
                     /locus_tag="PC503_001832"
     CDS             complement(2582..3247)
                     /locus_tag="PC503_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527805.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            3591..5021
                     /locus_tag="PC503_001833"
     CDS             3591..5021
                     /locus_tag="PC503_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2527806.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            5389..5967
                     /locus_tag="PC503_001834"
     CDS             5389..5967
                     /locus_tag="PC503_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2527807.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITISSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            5997..6143
                     /locus_tag="PC503_001835"
     CDS             5997..6143
                     /locus_tag="PC503_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2527808.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            6439..7818
                     /gene="scfB"
                     /locus_tag="PC503_001836"
     CDS             6439..7818
                     /gene="scfB"
                     /locus_tag="PC503_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF2527809.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            7847..8344
                     /locus_tag="PC503_001837"
     CDS             7847..8344
                     /locus_tag="PC503_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF2527810.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            8642..10306
                     /locus_tag="PC503_001838"
     CDS             8642..10306
                     /locus_tag="PC503_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF2527811.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEAIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            10319..12769
                     /gene="recJ"
                     /locus_tag="PC503_001839"
     CDS             10319..12769
                     /gene="recJ"
                     /locus_tag="PC503_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF2527812.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            12782..13294
                     /locus_tag="PC503_001840"
     CDS             12782..13294
                     /locus_tag="PC503_001840"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF2527813.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            13368..15575
                     /locus_tag="PC503_001841"
     CDS             13368..15575
                     /locus_tag="PC503_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF2527814.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            15600..16049
                     /locus_tag="PC503_001842"
     CDS             15600..16049
                     /locus_tag="PC503_001842"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF2527815.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            16064..16678
                     /locus_tag="PC503_001843"
     CDS             16064..16678
                     /locus_tag="PC503_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2527816.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            16769..18325
                     /locus_tag="PC503_001844"
     CDS             16769..18325
                     /locus_tag="PC503_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF2527817.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            18315..19577
                     /locus_tag="PC503_001845"
     CDS             18315..19577
                     /locus_tag="PC503_001845"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF2527818.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            19651..21438
                     /gene="aspS"
                     /locus_tag="PC503_001846"
     CDS             19651..21438
                     /gene="aspS"
                     /locus_tag="PC503_001846"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF2527819.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            21897..23129
                     /locus_tag="PC503_001847"
     CDS             21897..23129
                     /locus_tag="PC503_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2527820.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            23143..23949
                     /locus_tag="PC503_001848"
     CDS             23143..23949
                     /locus_tag="PC503_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF2527821.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(24061..24930)
                     /locus_tag="PC503_001849"
     CDS             complement(24061..24930)
                     /locus_tag="PC503_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2527822.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            25302..26729
                     /locus_tag="PC503_001850"
     CDS             25302..26729
                     /locus_tag="PC503_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF2527823.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVEIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(26806..27075)
                     /locus_tag="PC503_001851"
     CDS             complement(26806..27075)
                     /locus_tag="PC503_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527824.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(27078..28520)
                     /gene="nhaC"
                     /locus_tag="PC503_001852"
     CDS             complement(27078..28520)
                     /gene="nhaC"
                     /locus_tag="PC503_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2527825.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(28545..29711)
                     /locus_tag="PC503_001853"
     CDS             complement(28545..29711)
                     /locus_tag="PC503_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2527826.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(29936..32056)
                     /locus_tag="PC503_001854"
     CDS             complement(29936..32056)
                     /locus_tag="PC503_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527827.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQNFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            32289..32690
                     /locus_tag="PC503_001855"
     CDS             32289..32690
                     /locus_tag="PC503_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527828.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            32733..33026
                     /locus_tag="PC503_001856"
     CDS             32733..33026
                     /locus_tag="PC503_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF2527829.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            33041..33481
                     /locus_tag="PC503_001857"
     CDS             33041..33481
                     /locus_tag="PC503_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF2527830.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(33573..34046)
                     /locus_tag="PC503_001858"
     CDS             complement(33573..34046)
                     /locus_tag="PC503_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2527831.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(34046..34834)
                     /locus_tag="PC503_001859"
     CDS             complement(34046..34834)
                     /locus_tag="PC503_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2527832.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            35162..36406
                     /locus_tag="PC503_001860"
     CDS             35162..36406
                     /locus_tag="PC503_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2527833.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALITSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            36729..37826
                     /locus_tag="PC503_001861"
     CDS             36729..37826
                     /locus_tag="PC503_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2527834.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            37817..38515
                     /locus_tag="PC503_001862"
     CDS             37817..38515
                     /locus_tag="PC503_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2527835.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            38518..39582
                     /locus_tag="PC503_001863"
     CDS             38518..39582
                     /locus_tag="PC503_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2527836.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            39765..40469
                     /locus_tag="PC503_001864"
     CDS             39765..40469
                     /locus_tag="PC503_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527837.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            40462..41784
                     /locus_tag="PC503_001865"
     CDS             40462..41784
                     /locus_tag="PC503_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527838.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            41971..43344
                     /locus_tag="PC503_001866"
     CDS             41971..43344
                     /locus_tag="PC503_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527839.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(43716..44654)
                     /gene="pdaA"
                     /locus_tag="PC503_001867"
     CDS             complement(43716..44654)
                     /gene="pdaA"
                     /locus_tag="PC503_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2527840.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        17310 a         5086 c         7626 g        14905 t
ORIGIN      
        1 aaactataaa aatgtaaatt atttatataa atttataaag tttatgtgct agatgatatt
       61 ttttaggagg tagggttatg gcttacaaag gaataggtgc ttctcctggt gttgctttag
      121 ggaaagcgtt agtagttgaa catagtgaat tagtaattga aaaaaaatct atagataatg
      181 ttgaagctga aattgctaaa ttagaagatg cagttgcagt ttctaaagaa gaattagtaa
      241 aagttaagga aaaggcttct gaagaattag gagcagagga agcagaaata tttgaagcac
      301 atttattagt tttagaagac ccagagttaa ttggttctgc aatagataaa attaaaactg
      361 aaagtgtaaa tgcagagtat gctttaaatg aaataaaaga gatgtttgtt agcatgtttg
      421 agtctatgga caatgagtac atgaaagaaa gagcggcaga tataaaagat gttacaaata
      481 gaatacttag acatatatta ggaattaaag ttgttgattt atctgcttta agcgaagaag
      541 ttgtattaat agcacatgat ttaactccat cagacacagc aactatgaat aaaaaaatgg
      601 ttttaggatt tttaactgat ataggtggaa gaacttctca tactgctatc atgtctagaa
      661 ctttagaaat agctgcaatc gttggattaa atgatataac ttcaaaagtt aaggatggag
      721 attttgtggt tttcaatgga gacacaggtg aagtaatcgt gaatcctgat gaagagacta
      781 taaataaata tactgaatta aaagctaagt atgaagatga gagaaaagca ttacagctat
      841 taaaaggaaa accatctgta actttagacg gaaaacatgt ggaattagct ggtaacatag
      901 gaacacctaa cgatatagaa ggtctaataa agaatgatgc tgaaggtgtt ggtctttata
      961 gaacagaatt tttatacatg gatagagatt ctttcccaac agaagaaata caatatgaag
     1021 catataaagc tgtattagaa ggaatggatg gaaagcctat agttataaga acattggata
     1081 taggtggaga taaagaatta agttatttaa gtatggaacc tgaaatgaat ccattcttag
     1141 gttacagagc aataagactt tgcctagata gaaaagatat atttaagact caattgagag
     1201 ctttatatag agctagtgtt catggaagat taagaatcat gttcccaatg atttcatctt
     1261 tagaagagtt gttacaagct aaagaagttg taaaagaagt tttagcagaa cttgattctg
     1321 aaggtgtggc ttatgctaaa gatgtagaaa ttggtatgat gatagaagtt ccatctgctg
     1381 ctgtgatatc tgatgtattg gctaaacacg tagatttctt ctctatagga actaatgatt
     1441 taattcaata cacttgtgca gttgatagaa tgaatcaaaa gataagctat ctttacaatc
     1501 aatttaatcc agctgtttta agacttataa agactgttat agacaatgca cataaagaag
     1561 gcaaatgggc aggtatgtgt ggagaatctg ctggagacca aaaaatgata ccaatacttt
     1621 taggtatggg attagacgag ttctctatgt ctccaatatc aatacttcct gctagaaagt
     1681 taataacttc agttaaagag tcagatatga aaaaattagc tgatgatgta cttaatatgg
     1741 gtactgctga agaaataaaa agctatatag aaaagacttt taatatataa ttaatgttat
     1801 atagttacta aaattcattt ttctaaataa caaaattata ttttacgaat taaaaaggag
     1861 atgtttcaaa ataaaaattt gaagcatctc ttttttataa aagattacta agaattactt
     1921 aatctttgta atagtcattt tgtgaaaaag caaaactgca ttgtggctat agtatatatg
     1981 gatgttatta tcaataaaag tactattaaa atgaagattc attctcaaat gatatcaaaa
     2041 gtagttgtga tggagtaaga taatattttg tgatttaata gtaaaaatta aaaaaatatg
     2101 gtattgaaaa ataattaaaa gtatttaata atagaattag ggaagaataa gtttataagt
     2161 aaaaataatt gattactagt taataaaata aatgtgatat ccaaataaat cctaaatcta
     2221 atttgagttt taatatagat agtctaaagt ttgattatta aagatttaat tgtaagttgt
     2281 tacagttgat gatattgatt agagattaaa gtttagagta gaaagttacc ttaaatttaa
     2341 aaatgcaaga taacccaatc taaaaattat aatcactcaa taggtttaag gatttatttg
     2401 tttattataa ataggagggt gtctcaaaat gaacttttta gtttatgagg cactctcttt
     2461 tatatagaat taaatatatt ttattatttc aacaatgaaa aagaagctta tctctatttt
     2521 gagacagcct ctttgtatac tattattaat ttaatcaata acataattta aaactatatt
     2581 attagttaag atttcctgct ttattagtaa ataattcttt aatagcattg tttctggaaa
     2641 ctaaatcgtt atcagagttg tttgtttttt tcataatcac tgaataacgt tttttattta
     2701 taaaaaatat taaaatctta tcatcatcaa aattgtattc tttatatctg tcaatagact
     2761 cataacctag atttagaatg tttttgtctt ttatactatc tacatctaaa atatatgatg
     2821 ggtcagcctt tagtaatata ttaattaaac atttttcttc accagcacag aataactcca
     2881 tcttacttga tatagattta gattgctctg aagttatttt tgcaggaata aggttgtcat
     2941 tgtcatctct tagaagataa ccatgtgtgt cttgttgata tactaaatta acctttttct
     3001 taggaacact aatcatttta tctaaatgta cataatgatg attttcaaca aaaccttcat
     3061 ttaatatttc aacaaagtta ttaattttac ctaggcaaaa agattctata gattctttac
     3121 agaatttatt tgtaaatggt attatgttta cgttttcctc gtctgtattc catgctatag
     3181 cataatccaa cgaatatact tcttcctcta tatctgcaaa attatattgt actatgtttc
     3241 ctttcaaaat tactcgacct ccatcttata atatatttaa tatactttat aaaacttata
     3301 ttatatttaa ataatatcat aaattgaata aatatgatat agtaaataag aaaaaatttg
     3361 aaaaaaatca ctataaatga gtaataaata taaatagtgt atactaatgg gatggaaaat
     3421 gtccactatt aactttatta ccccacatat ataagataaa attattaata taaaatataa
     3481 tctatcgaca atgaatagac ttttaaataa acttaatata aaattaatta aataagtgct
     3541 taaaaacgat ttactttaat gatagaatca tattaaagga ggataatttt atggatataa
     3601 agaataaaat taaatctata tttttaccag aaaaaaatga ctatttagat gatgaagaat
     3661 ttgagtatga tatagaaaat aatgaagaag atttaaagga agataacaaa gtacatttaa
     3721 atgatttaag cagagtaaaa tatgattaca gagagttaaa agacatagaa aaccaaacag
     3781 aagagatgtg tctgctagca gtaaagcagg atggtactat aattgagttt gtaaaggaca
     3841 agacttataa agtatgtatg gaagcagtaa aacagacata taaatctctt aagtatataa
     3901 caaatcaaaa tgaggatatt tgtatagaag cagtaaaaca gaactacaga gctttgtact
     3961 acataaataa taagacagaa aatgtactaa ttgaggctat aaaaaatgca tcaacttatg
     4021 atgtcatgga agtatttaaa tttgtggaag agcaaacaga agatgtatgt ctagcattta
     4081 tagaaagggc atctaaaaat gatgttgcag agatattaaa aggaataaaa gagcaaactc
     4141 cagccatatg tttagaagct gtaaaaaaag atggaaaatc tttagcttat gtaaaggaac
     4201 aaagtaatag tatatgttta gaagctgtaa aagaaaacta cagtgcacta tcttgtgtaa
     4261 aagagcaaac tgaagaaata tgtatagaag cagtaaaaca gaatgacttt gcattgtatt
     4321 atgtaaatga acagacagaa aaaatatgca tggaagcagt aaaaagaagt tatatggctc
     4381 tacagtatgt aaataagcaa acagaagaga tttgtttgga agcagtaaga attgatggaa
     4441 gagcattaca gtacgtaaaa gagcaaacag aagaaatttg cttggagtca gttagacaaa
     4501 atggaaaagt actgcaatat gtaaaaaaac agactgaaaa tatatgtata gaagcagtaa
     4561 gaggttcatt tgaagaactt gaaataaaag aaatattaag ttatgtaaag ataccaacag
     4621 aaagaatatt tgtagaagca gtaaagcaaa atggaaaaat tcttaaatat gtagaaaatc
     4681 agacagaatt aatatgttta gaggcagtaa gagaaaacta taatgcttta gcttatgtaa
     4741 aggaacaaac agaaaagatt tgtttagaag cagttaatca aagttatgaa gcgcttaaat
     4801 atgtgaaaga acaaacagaa gaagtttgtc taaaagcagt aaaacaagat tatagaatgt
     4861 tgaaatatgt aaataatcaa acagaaaaaa tatgtttaga agcagtaaag caaaattata
     4921 gagctttaga atttgttgat aatcaaacag aaaaagtttg tcttgaagca gtaaaacaga
     4981 atagaaaagc actacagtat gtaaaacaaa aacaaagtta aaaggctaaa atatatgggg
     5041 aatatatgca aataaataaa atttgatatt ttgtaataaa taaaatgggt atctcaaaag
     5101 gaacttttta gtttgtgagg tactcttttt atatgaaatg aaatatattt ttagcctttt
     5161 aacaaagggg aaaaggtttg tttctatttt gacataggct ttttatgcat ataaagcttg
     5221 ataaaattgt tttattataa ttgttttgtt atataaataa taagaagaaa attatatagg
     5281 tctttttttg accagtttta catttttaac aactagtttt gtaaagtata ttgaattttc
     5341 tcaaaaaaga atgtactcta tatatgtaaa atttttttgg aggtaaaaat gtttaaaaga
     5401 tatgctgaaa aaatgacatc tgttttaatt tgtaataata tgatagataa taatgaatct
     5461 aaagtctatt cttatggatt tgaaatatta atagctttca tagttaatat aaccaccatg
     5521 ctgtttatag gttttttatt tggtaaattt acatatgtat tatttttttt aatgtgttat
     5581 tgtccaataa gacaattttc aggagggtat catgcagaca attattttag atgcttatta
     5641 acttttattt ttataatttt atccacaatc ttaattatag aaaatataaa tatagactta
     5701 tttaaaaata ttattatgat tattgcaagt gttagttggg ttggaatttg tgttctgtgc
     5761 ccaatagaac ataggagtaa ccctataagt gatagggaaa agttggttta taagaaaact
     5821 gctatattta tatctacagt agtgttattg ataacaattt caagtctttc tttgagtata
     5881 tttgtagatt atttcacata tagcgcattt gccatgtttt ggatttttgt gatgttagta
     5941 ttaggtaagt taaaagctaa agtataagta aaatatgtat gagggagagt taagttatga
     6001 aaaagtttat tgtaagattt atgaagtttg ctagctcatt ggcacttagc actgctattt
     6061 tgtcagctaa tagtacctgt ccttggatta ttcatcagcc taaagtaccc aaagaaatca
     6121 gcaatctaaa gaagacaaat taaatacaag cacttattta tacaaaatta tcaggaaaaa
     6181 agaaattatt atattttaat aagattaaaa caatataaaa tcagatacaa aatttatttt
     6241 ataggagcct aatacctatt tggtaatata ttagtgcgcc aatttagggg gatatagtgt
     6301 atttaatgaa atgacttacg gagagtaagt catttttgta ttgtatgtat tttatgtaaa
     6361 cttatgatat aatgaagggt aaagtttaat taaaataata aaaaacttta gtatagatag
     6421 taatttagga ggtagggtat gagtatgata cataaatttt ctatgaatgg atataatatc
     6481 gttttagatg tgaatggtgg agctgttcat gtgttagatg atgttgcata cgatttgtta
     6541 gatttttata aagaaaaaag taaagaagaa atattagaga tattaaaatc aaaatatcaa
     6601 gaagaaaaaa taaatgaagc atatgaagaa atattaaatt tggaaaaaga gggtctttta
     6661 tatacagaag atacatatca atatcatcca agctttgtac atagagagcc tgtagtaaaa
     6721 gctttatgtt taaatgtagc tcatgattgt aacttaaaat gtaaatactg ttttgcagct
     6781 caaggtgatt ttggaggaga aaaagaactt atgagttttg aagttggtaa ggcagcaatt
     6841 gactatttga ttgctaattc aggaagtaga aagaacctag agatagattt ctttggtgga
     6901 gagcctttga tgaactttga agttgtaaaa caactggttg actatggaag aagtgtagaa
     6961 aaagattata ataaaaatat aagatttaca ataactacaa atggtgtact gctaaatgat
     7021 gagattatag attatataaa tgaaaatatg cataatgtag ttttaagttt agatggaaga
     7081 aaagaagtta atgataatat gagaccaact ttaaatgata aaggaagtta tgatattaca
     7141 ttaccacgat ttaagaaact tgtggaaaaa agagcaaaag ataagtatta ttatataaga
     7201 ggtactttta caagagataa tttagatttt tcaaaagatg ttatgcattt tgcagattta
     7261 ggatttaaat taacctctgt agagccagtc gttggagatg agagtaatcc atatgcactt
     7321 agagaagaag atttacctaa gatatttgaa gagtacgaaa aatttgctgt agagtatgca
     7381 gatagacaat tacaaggaga tggatttaaa tttttccatt ttatgataga cctaaatcaa
     7441 ggtccatgtg taataaagag aataactgga tgtggagctg gaaatgagta tctttctgta
     7501 actccaaatg gagatatcta tccatgtcat caatttgttg gaaatgaaga atttaaaatg
     7561 gcaaatatat ttgatgaaga aatagtactt ccagaaaatt taaaaaatat gtttagagaa
     7621 gctcatgtat atactaaaga agagtgtaaa caatgttgga ataagtttta ctgttcaggt
     7681 ggatgtcatg caaatgcgat aaactttaat aatgacatat caaaaccata tgaattagga
     7741 tgtgaaatgc aaagaaaacg tacagagtgc tctataatga tacaagctaa gttaatgtta
     7801 gaaggagcaa ccaactaaat ttatatttta aaggagttgt ttatatatga ttagagatta
     7861 tttagaagat aaacctttaa ttgacgaaag tgtatttgtg gcaaaatcag cagatgtaat
     7921 tggaaatgtt aaaataggca aagattcaag tatatggtac aatgcagtag ttaggggtga
     7981 tgaaggacca ataactattg gagaaaacac taatatacaa gattgttcta tagtgcatgg
     8041 agatacagaa actataattg gtaacaatgt aacagttggg cataggtcta tagttcatgg
     8101 ttgtaaaatt agtgataatg tgttaattgg tatgggttca ataatattgg ataatgctga
     8161 aataggagaa tatactctga taggagcagg tacactaatt acatctaata agaagtttcc
     8221 gccaggtgtt ttgataatgg gttctcctgg taaggttgtt agagagctta cagaagaaga
     8281 taaaaaatat attgatgaat cttatgaatg gtatttagag gcagcacaaa atcaaaaata
     8341 ttagtttaaa gagtggttgt ttcaaaacat atttaaatct gttttgaggc aaccactaat
     8401 ttattttatt agattttgtt gatattttag ttttcaaaaa gtatttgatt aaaccagata
     8461 taaaatgtca aaaataaaaa ttaactgagt taaataattt taataaaatt ggtagtatat
     8521 gtgataaaat taaatattaa agaggatata ggatattaga atatcaattg gtgaaataat
     8581 gtcatatacg ataaattaag gtgtaagttt ttgggtatac ctatcttagg agtgaaaaga
     8641 tttgagaata agttatagaa atttaaagcg atatagagaa attggatatg ttttaataaa
     8701 gtatggtttt agttttattg tagaaagact aaatatagaa ggaattgcct ataaaatacc
     8761 actatttgac ccaccagaag aaataaaaaa tatgacaact ggtgagagaa tgaaaagagt
     8821 tttagaagaa ctaggaccta catatataaa aataggacag atattgagta caagaaaaga
     8881 cttgttagac caggatataa ttgatgaaat atcaaaactc agagatgatg tagagaaatt
     8941 tgattcaaat atagctattg atatatttaa agaagaagtg ggtttaagta tagaagaaat
     9001 attcttagaa tttaaagaag aagcaatagc agcagcttca attggtcaag tttatgaagg
     9061 tgtacttaaa acgggagaag aagtaatcgt aaaaattcaa agaccaaata tagagaaaat
     9121 aataaaatct gatttagaga ttcttagaac tattgcaaat actttaaaag atttaaaaaa
     9181 ggattttaat ttagatttag tacagatgat tgaagaattt caaactcaat taatgaggga
     9241 acttgattat acatttgaag ctataaatgc aactaaattc tctaggatat ttaaaaatag
     9301 tgatgaagta tatataccta aagtatattc agaatataat actaagaaaa ttttagtaat
     9361 ggagaaagtt aatggtacaa agttaagtga tgtagaaaaa ataaggagac taggttataa
     9421 cacaaaaact attgttgaaa taggcgttag gtcatttttt acacaggtat tatctcatgg
     9481 attttttcat gcagacccac atccaggtaa tatattcgta gttgctaaaa ataagatagc
     9541 atatatagat tttggaatga ttggaattat tgataataaa actttaaacc aattaaatga
     9601 aattgcatta gcaggtgtag aaaagaatgt tgacaagata atatatctat tgatagaaat
     9661 ggatgcatta aatggagagg ctgatattaa gggacttaga caggatttac tttatctaat
     9721 acattattac tatgatattt ctatagaaaa aataaatgta acagatatat taaatgaact
     9781 atttaggttt tttagacagt ataaaatagt catgcctgca caatttgtaa ctcttgcaaa
     9841 gacagttata acattagaag gaacaagtag aactttaaac acagattttt cttttggttc
     9901 tatgggaaaa gagtttatga aacatcatta taagagtaaa tttaacccta aaaatgttgt
     9961 tttaagttca agacaaaatg tagaagaaat attactggac ataaaaacta ttccaaagca
    10021 attaaaagca attttaaaaa atatagaaag aaataatata aaaatgcaaa ttgaagatgt
    10081 taaaatgacg aggttagaaa attgtataat agagctaaca tctcaaatat ctttgagttt
    10141 agtgttggca tctattatag taggttcttc tcttataatt gcatctccaa atatagaaaa
    10201 taatatatgg ataaaattta ctgcaatagc gggtttcttt atatccttta taataggcct
    10261 ttgcttagtt ataagaagta ttaggtcaaa atacaaaaaa gattaggggg aattaaattt
    10321 gaaaaaatgg atattgaagt ataaaggtaa gatagaggaa agtgaattta gcaaaaaact
    10381 taatatttcc ccggaaatct gccaaatttt aaaaaataga gggatatgta ctgaaaaaga
    10441 ttcagagata tttatgaatc catctttaga ttatttaaga gacccttttt taatgaaaga
    10501 tatgcaaaaa gctgttgata gaataaagtt agcagttgag aagaacgaaa aaatttggat
    10561 ttacggagat tatgatgttg atggtgtatc atctacatct atcttgtgct tatattttaa
    10621 gagtataggt tacaatgttg attactatat tcctaataga ttagaagaag ggtatggtat
    10681 aaatgaagat gctattaagc ttataagctc taggggatgt gacttgatta taagtgttga
    10741 ctgtggaatt acatcagtgt ctgaggtcaa tacagcgaat gatttgggca tagatgttat
    10801 aattacagac catcatgaat gtcaaagtga aattccatca gcctttgcag taataaatcc
    10861 aaaacaagaa gattgtaatt atccatttga ttcactatgt ggatgtggtg tagcatttaa
    10921 aatgattcaa gccttgactc caaaagaaga atttaaaact agtatgtata attatttgga
    10981 aatagtaaca ctagcaacta tttgtgatat tgttccactt atagatgaaa atagaataat
    11041 tgtaaaaaat ggtttaaaat caatgaaaga aggcaaaaat attggattaa gggagcttat
    11101 aaaagtttgt ggtgtagaaa gtgataagat aggttcttct catataggtt ttgcaatagg
    11161 tcctaggata aatgcttcag gtcgattggg atattcttac ttaggagtag agctatttac
    11221 tactcaatca caagaagagg cagtagaaat agctagtata ttggaagaaa aaaataatga
    11281 aagacagatg atagaagcta agatgtatca tgaagctgag gaaatgctaa agtctaatag
    11341 cagatacaat gatgacaagg tgttggtttt agctaaagag ggttggcaac atggaataat
    11401 aggaattgta gcatcaaagt taactgaaaa atactacaaa ccaacaattc ttctaggtat
    11461 agaaaatggg gaggctactg gttcagcgag gtcaataaaa ggatttaata tatttgaagc
    11521 tctcataaag tgcaaagact tgatgactaa gtttggtggt catgaacaag cagcagggtt
    11581 atccttggat tcagacaatg tagaaatttt agcaaatgaa ataaataaat ttgcagatta
    11641 taatttaact gaagatgata tgatagagaa tgtaaatgtt gagtttgaat tacaagaaaa
    11701 tgtaataaat ttaaatcttg tagaagaatt acataagtta gaaccctttg gattaaataa
    11761 tcctaatcct agatttatag ttagaaatta tattttaaaa gatttgaaag ttataggtaa
    11821 gaatcaacaa catctgaaat taagcataga aaaagagaaa agctatgaat gtataggatt
    11881 taatatgagt catttaaaat caatgtataa agtaggagac aaggtagatg tactattcca
    11941 attagatgaa aataactata tgggaaatag gaaagtacaa tttttactta aagatatacg
    12001 attggctcga cctaaaagtg caagtaatga caaactttca ttgaaattaa tgtcaaaaat
    12061 aataccaaaa gatactcaaa gcctgtataa tatatctgtg tctgattttg aattatttga
    12121 tggaaataca gatataaata tatttgatta ttttgaaaaa gatacactaa taatatctaa
    12181 ttctataaat ggattttata gagcaatgtc agatatatca cttatagatt tggattttaa
    12241 cataaattac aatattattg aagatgttag caaaaatact gataaattag agcttatatt
    12301 ttctcctaat attgataaaa tagacttaaa aagatataat aatattattc tttatgatta
    12361 tttatacaat aaaggcgaat attcgtatat atatgagaat aaaagagaag aaagtgaaat
    12421 tataaaatat tataataaaa cagacctatt atatttaaag aatgtagtta gtaatatagt
    12481 tccatcaaga gatgaattta taacaattta taaacaagca ctcataaaaa aagaaattga
    12541 tttggatatg gtaaatataa gggaaacttt taatgtaatt ccattaaagt tttttacgat
    12601 attaaatgta tttagagaat taaatttact tgactttaat ttaaattatg aaaaaaattc
    12661 tgtactcata agaatattgc caaaaccaca gaaaaaatta gacttaaatg agagtttaat
    12721 actcaataat ctaaaaaatt tagaaaaaca atacaatagc agttattagg aggcgtttcc
    12781 catggattta aaaaacttta taaggaatat tgatgatttc ccaaagccag gcatagattt
    12841 taaagatgtg acaactctat ttaaagatgg agatgcattt aaatatgcag tggattctat
    12901 agttgaagaa ttgaaagata aagatgtaga tttagtaata ggaccagaag caagaggatt
    12961 tttgatgggt acacctgtag catatgcttt aggagtagga tttgttccaa ttagaaaacc
    13021 tggaaagtta ccaggtgaag ttgagagtta tgagtatgga ttagagtatg gtacagatac
    13081 tttagagata cataaggatg caattaaaaa gggtcaaaaa gtagcaatag tagatgattt
    13141 attggctact ggtggaacta tggaagccgc tgccaagctt gtagaaaaat taggtggaga
    13201 agtagtttct atgcaatttt tgattgagct aaaattctta aatgggagag aaaagttgtc
    13261 taactatgat gttaattctc ttataaaata ctagtacttt tataatagtt ggtataacac
    13321 caactatttt catatatatt aaaattttat acaaaatagg tggttatatg catgataaag
    13381 aattacaaga aataattgaa aaaataaaag tttatgcacc taatgcaaat tttgaaatgg
    13441 ttgaaaaagc ctataatctt gcaaaaaaag cgcatgaagg acaatataga aaatctgggg
    13501 aaccatactt tattcatcca ttagcagttg caaatatttt aatagagatg gaattagata
    13561 ttgaaactat aacagcaggt ttacttcatg atgttgtaga agatacagaa tatacctatg
    13621 aagacataaa aaaagaattt ggcaaagaag tagcggattt ggttgatgga gtaactaaac
    13681 ttggtcaaat aaaatatcgt tcgaaagaag aaactcaatc tgaaaattta agaaaaatgt
    13741 ttttggcaat ggcgaaggat ataagggtta tacttataaa acttgctgat agattgcaca
    13801 acatgagaac attaaaatac atgcctccag aaaaagcaaa gtataaagca aaagagacac
    13861 ttgaaattta tggtggtata gctcatagat taggaatttc caagataaag tgggaactag
    13921 aagacagagc attaagattt atggacccag aagggtatta tgatttagtt agtagagtat
    13981 caatgaagag aagtcaaaga gaggattata ttcaaggaat tgttgaactt cttaaagata
    14041 agtttaaaga tttaagtata ccatgtgatg tatatggtag accaaagcat ttttacagta
    14101 tatatagaaa gatgcaaaaa aaacataaga cttttgaaga gatttttgat ttaacagcag
    14161 taaggatatt ggttgataat gtaaaggatt gctatgcagt acttggtata gttcatacat
    14221 tatggagacc tattccagga agatttaaag attatatagc aatgccaaaa cccaatatgt
    14281 atcaatcatt acacaccact gttgtaggtc ctgatggaga acctttagag atacaaataa
    14341 gaactcatga gatgcataat atagctgaaa atggtatagc agcccattgg aaatataaag
    14401 aaggtatctc tagcaaagaa tcaaaggttg aagaaaaact tcaatggttg agacagatga
    14461 tggagtggga aaaagattta aaagacccac aagagtttat ggatgcactt aaagaagatg
    14521 tatttaatag tcaagtttat gtatttacgc caaaaggaga cgtaattgaa ttaccagcag
    14581 aatcaacacc tatagatttt gcctataggg ttcatacaaa tgtaggcaat aaatgtgtag
    14641 gagctaaaat tgatggaaga atagttccta ttgattataa gcttcaaaat ggtaatattg
    14701 tcgaggtact tacatcatct aattctaatg gaccaagtag ggattggctt aatatagtga
    14761 agaccccaaa tgcaaaaagt agaattagac aatttttcaa gaaggaaaga agagaagaaa
    14821 atgttgaccg tggaaataca atattagaaa gagaatttaa gaagcatgat ataccacaaa
    14881 aagaccctct tgttgaaaaa tatatggcat tagttgctaa gaaatttaat cagccaagtg
    14941 ttgaggactt aattgccact gtaggttatg gtggtataat gtcatctcaa gtggtatcta
    15001 aggtaaaaga cctatattta aaagaggtta aaaaagctaa aaaggaacaa cagatacaag
    15061 aagaagattt aaataaacac aatataagtg aaacagaata cagtaaaaag agaaagaaaa
    15121 acgcatcaca aggaattata gtaaaagggc ttgacaatat cttagtaaga tttgctaagt
    15181 gttgtaatcc tcttccagga gatgaaattg taggatatat tactaagggt aggggagtag
    15241 ccatacacag agctgattgc ccaaatgcaa acaataatgg tgatttcttc caaaatagat
    15301 tggtggaggt ttcatggagt tcagcaggaa aaggtaagtt tgaagcggaa attcaaataa
    15361 aagctattga tagaagagga attgttaatg aaataactca tattgttgca atggataaac
    15421 ttagtttaaa cggaataaat gcaagaaaag gtaaggatag tattgtaagt ataaacttac
    15481 ttgtagaggt taatgacaca gaggaattaa aaattctaat gaaaaaatta aaagcaattc
    15541 ctggtgtaga aagtatttat agaatgacaa attagagtta aaataatagg gaggaaacta
    15601 tgagagcagt agtgcaaaga gtatcttcat ctaaagttac agtagatgaa aacactatag
    15661 gtcaaataaa taaggggtta ctagtattgt taggagtgac tcatgatgat aaatcaagtg
    15721 atgtagatta tatgattgat aaaatattga atctgagaat ttttgaagat gaaaatgaca
    15781 agatgaattt atctctaatg gatataggtg gagagctttt agtagtatct caatttactt
    15841 tatatggaga ttgcagaaaa ggaagaagac ctggatttag taatgcagct aggccagaac
    15901 ttgcaaataa cctttatgaa gaatttgtaa aaaaagcaaa agataaaggt gtgacagttg
    15961 gtacaggtca atttgcagct catatgatgg tagagttaac taatgatggt ccagtaacaa
    16021 tactattaga ctcaagtaaa tctttttaag ggggaaaact ttaatgatta taaaaaaatt
    16081 tgtagatagt tattttggag taaatactta tgtattaggt gatgaaaaga ctaaaaaatg
    16141 tgcagttata gacccaggtg gaagtttagt agagacatta agttttgtaa aagaaaatga
    16201 attaaatatt gaatatatta tccttactca tgggcatgga gaccatatag gatatgttaa
    16261 ggatattaaa gaaaaaactg gtgctaaagt agttgcacat gttgatgaaa aagaattatt
    16321 aaatgacaaa aataaaaatc taagttatac aatgagatgt ggagcgcaag agtttgatgc
    16381 agatatctat gtaaatgata aagacaagct tgaacttggt gaattaaaaa tgactttctt
    16441 gcatactcca ggacatactc aaggatgtat gtgtataaga gttgaagatg aaatgttcac
    16501 aggagatact ttgtttgctg gaagtattgg tagaactgat ttatatagtg gagactttaa
    16561 ccaaatggaa aaatcactta agaaattatg taaatatgaa gatgctgtta gagtatatcc
    16621 tggacatgga ccaaccagta ctctaggggt tgaaaagaag acaaatcctt acatgtaatt
    16681 ttatattagt atttaaaaaa gtataaaata tttaataact atattagtga gggggttctt
    16741 ctactgttaa atagaaggag ttaagttgat gttgtatgtt tttttaaaag gacatgatta
    16801 taagtatgaa gtagcagaac ttataaaatt gtttactagt gaatttaagt ttaaagactc
    16861 taatgctaac aataatatag agtcaaagca tttaataaat agattgattt atgagaatgg
    16921 tgtattattc tcaagtactg aatactatga aaatggaaac ttaaagtacg agtcaataca
    16981 gaatatagaa aatatgaatc ttgaattttt agatggattt gatagcagca aaacgattga
    17041 agaatttctt aatagcctag atagtgaaag taagaggaac tttaaaaagc tgtgtaaaga
    17101 aaatatcaaa aaaagcatgt ttttagtgct taaacaagta tttaattctt atgtaccatg
    17161 gggaattttg actggtatta gaccagtcaa aattgtccac aatttaatgg ataaaaagct
    17221 agatgataat agcataagaa ccattctaaa agataattat tttataatag atgagaaaat
    17281 agatttagct cttgaaatag ctaaaagaga gcgattattt atgtatccta tagataaaaa
    17341 taaaatttct ctttatgtaa gtattccatt ttgtccaact agatgtgtat attgttcatt
    17401 tccttcaaat tcattaaaac aatttggaca tttaaaaaga gaatatgttt ataaattgat
    17461 tgaagaaatt aaggggtttg ccaaagttat taaggatact aagaaagaag ttgaaactct
    17521 atatattggt ggtggaactc caactacact tgatgaggaa gaattggatt tgcttataaa
    17581 ttcattgttc aatgaattag atttaagtaa aattaaagaa tttactgtag aagcaggtag
    17641 acctgacact attacagaac aaaaactaag agtgttaaaa aaacacaatg ttagtagaat
    17701 tagtataaat cctcaaacta tgaatgatga taccttggta aagattggaa gagagcatag
    17761 agtatctgat ttagtagatt gctttaatat ggctcgtaga atgggatttg ataatataaa
    17821 tatggatata attttaggtc ttatagatga agacttaaat atggtaaaga acacattgga
    17881 ggagataaaa aaactttctc ctgaaagcct tacagttcat acattagcca taaagagagc
    17941 atctaactta aatataaata tggataggta taaagaacat ctaacacaat atgaagaaat
    18001 ggtaaaaatg atagatttat caatgaaata tgcaaaagat atgggattaa atccatatta
    18061 tatgtacaga caaaaacata tgttgggaaa tttagaaaat ataggttatg ctaaagaagg
    18121 atatgagtgc atttataata tacagattat ggaagaaaaa caaagtaact atgcattagg
    18181 tgcaggtgct atatcgaaat ttgtctatgt agatgaagat agaattgaaa gagtagaaaa
    18241 tgtaaaaaat gttgaacaat acattgaaag agtagatgaa atgataaaaa ggaagaaaga
    18301 agaggtatat aaaaatgttg actaaagctc ctagaggaac taaagacata actccaaaag
    18361 aggcttacaa atggcgttat gtagaaaata aatttagaga aatatgtgct ttatatggat
    18421 atgaagaaat ggtaacacct atatttgaac atacagaact tttcaagaga agtgttggag
    18481 atactacaga tatagttcaa aaagaaatgt attcttttaa agataaaggt gatagagaaa
    18541 ttaccctaaa gccagaaggt acagcaggtg tagtaagagc atttatagaa aataaattat
    18601 atgcagatac tcaaccaaca aaattatttt atgtgacacc ttgttttaga tatgaaagac
    18661 cacaagctgg tagacaaaga caatttcacc aatttggaat agaagcactt ggaagtgata
    18721 ctccttcaat ggatgctgaa ataatcgcac tagctgttca attttttaat gaagttggat
    18781 taaatgattt ggtagtgagt ataaattcag ttggctgtcc agtttgtaga aaagagtaca
    18841 atgctttatt aaaagagtat cttgactcaa aagctgatat attgtgtgat acttgcaatg
    18901 agagaagaga aaaaaatcca atgagggtta tagactgtaa aaatcctaca tgtaaagaaa
    18961 atatcaaaga tataccattt attgcagacc atttgtgtga tgattgtaaa tctcactttg
    19021 ataaacttca agaatactta aaggaaatga atataaactt tgtaattgat aaaacaatag
    19081 ttagaggctt agattactat agaaaaactg cttttgaaat tatatctaat gatataggag
    19141 ctcaaagtac tgtatgtggt ggaggaagat atgatggtct tgttgaacaa ttaggaggac
    19201 caaaaggtat aagtggaatt gggtttggac taggaattga aagactttta cttacacttg
    19261 aaggtaatgg aattgaaata gaaaaccctc aatctacgga tatatttata gtaactatag
    19321 gtgaagaagc aaatacaaga agctttaaat tgttaaaaga cttgagacaa aatcatataa
    19381 gtgcagataa agaccatata gagagaagtg ttaaagcaca atttaaatat tcagataaaa
    19441 taaattcaaa atttacaata gtaattggag atgatgaact taaaaatgac actgcgacat
    19501 taaaaaatat gaaaacatca gagcaaacta ctgtaaaatt aagtacatta gttgaagaat
    19561 taaagcaaaa gctgtaaaat aagaaagtat gatgttttgt gtattagata aatatatagc
    19621 attaaaatta aataaaatgg aggtagtatc ttggaaactt taaagggttt aaagagaact
    19681 cactactgtg gagagttgag agaaaaaaac ataaatgaag aagtcgtact tatgggatgg
    19741 gtacagaaaa aaagaaattt aggtggtctt gtatttgttg atttaagaga tacaagtgga
    19801 ttatgtcaaa tagtttttga tacagatgta gataaagaag cttttgaaaa agctgaaaaa
    19861 ttaggggctg aatttgtaat agctgtaaaa ggaaaagtat gcgaaagaca atctaaaaac
    19921 cctaatatgc caactggtga tatagaaata tttgcaactg aacttagact tttaaacaag
    19981 tcagaaactc cgcctattta tataaaagat gatgatgatg tttctgaagc actaagatta
    20041 aaatatagat acttagattt aagaaaacca tctatgcaaa gaaatttaaa attaagacat
    20101 aaagtaatga atattacaag aaattactta tcaaacaata gattttgcga aatagaaaca
    20161 ccatttttaa tagctccaac accagaagga gcaagagatt atctagtacc aagtagagtt
    20221 aatccaggaa aattttacgc attaccacaa tcaccacaat tatataaaca attattgatg
    20281 gtaagtggta tggatagata tttccaaata gttaaatgct ttagagatga agacttaaga
    20341 gcagatagac aaccagagtt tacacaaata gactgcgaaa tgtcttttgt tgagcaagaa
    20401 gatgttatga gtatgattga aggtttgctt gaagcgatat ttaaagaagt tttagatgta
    20461 gaattggcac ttccacttcc taagatgact tatgcagaag ctatgtctaa atatggttca
    20521 gataaaccag atactagatt tgggtatgag ttaacagata tatctgatgt tgtttgtaac
    20581 tgtggattta aagtgtttgc tgatgctaca caaccaggaa aaagtgttag aggtataaac
    20641 gtaaaaggca aagctgacga ctttactaga aaacaaatat catcactaga agaacatgct
    20701 aagacatata gagcaaaagg tcttgcttgg atgaaagtag gacaagaagg agtaacttct
    20761 ccaatagcaa aattcttcaa tgaagaagaa atgaacgcta tacttacaag aatgaatgct
    20821 gaagtaggag atttactttt atttgtagct gataaaaact caatagtatt tgatgcttta
    20881 ggacaagtta gacttgaagt agcaaatagg cttaatctat tggataaaaa tgtatataac
    20941 ttactatggg taactgagtt cccagttttt gaagaagatg aagaaacagg cacattctca
    21001 gcaatgcatc acccatttac atcacctatg gatgaagatt tagacaagtt agaagaaggt
    21061 gataagtcat ctttaagagc gaaagcttat gatattgtat tgaatggtta tgaaataggt
    21121 ggaggaagtg ttagaatatc aaattctgat gttcaatcaa gaatgtttaa agcacttggt
    21181 tttacagagg aaagagctaa tgaaaagttt ggttatttat tagaagcatt taaatatggt
    21241 actcctcctc atgctggtct agcttttggt cttgatagac ttgttatgtt acttgcagga
    21301 actgataata taagagaagt tattgcattc cctaaaaatc aaaatgctgt ttgccctatg
    21361 acaaatgctc ctacattggc ggaagatgag caattagaag aattaagtat aaaagttgat
    21421 ataaaagata atgaataata tgtagttgca agaaactaaa atgtaaaaag tctggatata
    21481 aaatatattt atattcagac tttttttatt agaattattt tatatttttt ctctatatat
    21541 tttcataaat tatacttata ttcttaacca atataattaa aatactatgt ttaaaaattt
    21601 tacataaact tggttgtttt agaaactact tctgtaacga gtacacgatt ttaattaaag
    21661 aatatataac aaatttgaaa taagtctaat atatgactta atagattaaa ttaaaataat
    21721 aaatttggac tatttatcta tttataactt aaattatatc aaattgataa caaactagat
    21781 attatacttt tttgtagaat agaattacaa ttatataaag aaaaattcta ttaatagtga
    21841 aaaaaaagta gaaaaaagta gaaattattc ttttataaag aaagggaggg ataatattgc
    21901 aagagagaga agaattagtt ttaaatccag ttccaaaaga ggaaagagtt ggatggttag
    21961 ctccattgtt taatatgctt ggttctaaca tagctatatc tgaactaatg gttgggggaa
    22021 ctttaatttt aggaatgact ctttctaata tgattattac atcaattata gggaacttaa
    22081 tattagttgc aattattatg atacaaggtt atataggtta caaagaaggg ttaaatacgt
    22141 atgtattagc taagggggca tttggagaga taggaggaaa gtatcttata tctctattac
    22201 ttggtataac tagttttgga tggtttggtg tacaagcagg ggttgcagga ctatcagtac
    22261 aaaagatatt cccaagtgta aacctaacat tagttacagt tatacttgga ttatttatgg
    22321 ttgtttttgc actgtatggt tttaaagcta tggctaaatt taattactta gttataccac
    22381 cacttatgat attaatggtg tggggagttt ttaaagcttt ttctacttat ggagttgaag
    22441 ctatttataa ttatactcct caaacaacta tgagtatggt tgaaggtctt aatattgtag
    22501 taggtcttgt tatagttggt gcaattatat cacctgacca gttaagatat acgagacgag
    22561 taaaagacat ttggattatc agttttttag gtctagggat tatttcatta ttccaacaag
    22621 ttgcagctgg tgtaatgtct atgggagcac ctacttggga tataacagaa gtattggcta
    22681 atttaggttt tggatgggta gcgtttgtta ttttaatact tgcatcttgg tctacaaacg
    22741 tatcaaatgc ttattctggt ggattagcat taaaaactat ttttccaaat gtaaaaagaa
    22801 atgttttgac tttagttgca ggtctaatag gtacaataat agcagctact ggtataatat
    22861 ttaaatttca gtcattttta tctttcttgg gaatcgcagt tcctgcaata gcaggaatta
    22921 tgtggtgtga gtattatttt atacaaggaa gaacttataa gcatagagaa ggaataaatt
    22981 ggattgcagt aataagttgg ttaataggtt ttgcagcgtc gtattatagt tcaaaaataa
    23041 atttcttaat acctccgata aatggaattg tagtgagtat ggttatttat tatatattaa
    23101 tgaattgttt tggaatcaaa gataaataaa gggggcaatt acatgggtcg taaggtgaaa
    23161 ataggtataa ttcaacaaca cagtgtactt ggaaatgtta aaaaaaatat agaaaaagca
    23221 gtagagatga tagatgactt aggaaaacaa ggggcagata taatttgttt accagaacta
    23281 tttgctacag gatataattt agagtcttta ggtggagtta aaacattaga attaataaga
    23341 gaacataata agtacataga ggaatcaatg tcagaagctg ctaaaagaaa taatgtatac
    23401 ctgatatctc catatggaac cttagaaaaa gggtctacac atgtttataa ttcagcagtt
    23461 atatttgata gaaaaggtaa gattatggga gaatactgta aaaatcatct gtggtcatta
    23521 gaagcagtat actttaaagg aggggaaaaa gtagaggtat atgatgctga ttttggtaga
    23581 tttggtgtaa tgatatgtta tgatgcaggt tttccagaag tatccagaga attgacatta
    23641 aaaggttctg aaataatatt tataccatct gcatggagaa tacaagatga agatatgtgg
    23701 gatttaaatg tatctcaaag agctttagag aacactgtat atacagtagg tgtaaattta
    23761 gtaagtaatg actctaattt aatactattt ggaaagagta aaatatgcaa tcctagaggt
    23821 actgtaataa ctcaattaga tacatacagg gaaaaatatg tattatcaga gattgattta
    23881 gatgaaataa aaaagtatag ggaagatatc ccctatttga aagacagaaa aagtagctat
    23941 aacatataat tctatactat aatacaagtt caatataaaa tgataaaaag aggatgtatc
    24001 aatattaaga ttaaatttat tatactttga tatatcctct ttaatattat caactttgat
    24061 ttaaatattt ttaaaatagt tgataagaaa gtttttgaac aacaacacag ctttagattc
    24121 atagttttcg ctaaaccatg aaagatttaa atatctttta aattcaatat ctttgatatg
    24181 taacaactta atctcagggt cttgagataa tccccatgat tttccacata taaatccaac
    24241 tccttgaagt gattttataa gagcataaat tgtatatggt gaatcagact caaatgctat
    24301 tttgggtttg aaattagctg attcgcacag gatatcaatt acctctctat aattctcacc
    24361 cttcgttata actataaagt tttcatctga aacttcgctt agatatactt catcctttaa
    24421 tgataaagga tggtttattg aaactcctaa tagtatttct tcgcatgtta aagttatgct
    24481 attttctgag tttagctttg taaatgaaga agatatgtac aaatcaaaat cacttttttt
    24541 ataagatgat ggcaaagtat gtgacacatt aaaagtaata ttgggatata gttttctgaa
    24601 attactcaaa agtgatggta acacattagc cgctgcagga gataatatct ttacttctcc
    24661 tgaattttcc aaagaagtgt cttgtaactc cttttttgaa ctttctacta aatctaaaat
    24721 gctatctact ctttttagaa acaatcttcc atactcattt aaaacaatat atcttccttt
    24781 tctgtcaaat aactgaactc caagttcttt ttctaaggaa gatatagttt tgcttaaagc
    24841 tggctgtgct atatttaact tgtgtgatgc ttttgttatg tgctccattc tagcaacagt
    24901 ttgaaaatac ttaagatgca ataaatccat agtataaaat acacctcttt taatatgact
    24961 tgagttatat caattttata atcaactcca cattatacat tataatataa agtttatata
    25021 ataaactaca atatattaaa aagttattta aattgttatt tatattttgt acataatcta
    25081 attaaaaaaa gtaactttaa atggttaact aaggaaatat tgttacaaac tttagttata
    25141 taaaaaattc gtttgatgag caaagtatta atgtcaagta agaataaaag cttattagat
    25201 aagaaaaata atattttata ataatgatgt tacttaaatt attatgttat actattttaa
    25261 ataggaaaca tttagatact ataattttag ggggagtcaa gatgaaatta actaaatcaa
    25321 tatcatcaat gctgtgctta tctctagttt taagcttatc accagtagca tatgcaaatg
    25381 aaataagtag aacaacagtt gagaatactt tagtaggtca ggatagatat caaactgctg
    25441 ttgaagtaag taaaaaagga tggagtagtg caaatgaggc tgtagttgta aatagtgaat
    25501 ctattgtaga tgcattagct gtaacaccat ttgctaaatt aaaaaatgct cctatattat
    25561 tgacagaaaa aaataatcta aattcacaaa ctgagaaaga attaaaaaga ttaggagtta
    25621 aaaaagttta tataattggt ctatctagtt ctgtatcaaa tgatgtgcaa aaacagttag
    25681 aatctaataa tttaactact gatagagttg gtggtagtga tagataccaa acagctttga
    25741 gtatagctaa aaaaatagaa ggattaaaag atatatcaga aatagctgta gtaaatgggt
    25801 acacaggtct tgcagatgca gttagtatag cttctgtagc tgctactaat ggaatggtta
    25861 tacttccagt atctgatgca tctggtatat ctagctttaa agattttata gaatctaaga
    25921 atataaataa atcatacata ataggctcta ctaatgctgt atcagataaa ataaaacaaa
    25981 gtttacctaa ttcagaaaga ataggtggag cagatagaaa tgaaactaat ggtaaagtaa
    26041 tagaaaagtt ttatacatct aataaattaa acaatgtatt tgtggctaag gatggaatga
    26101 aaaatcaaaa tcaacttata gacgctttag cagtaggagt actagcatca aaagaaaatt
    26161 ctcctgtact aatcgtagga gaacaattaa gtgcaacaca aaagagtgta ttttcgaata
    26221 aaaatgctac ctctataact caagttggta gtggaggaaa tgaaaatgca tttaaagaat
    26281 taaaagattt acaggcaaat agtaacaata agagagtaat gtatgtaact aatacagata
    26341 aggtaaatat aagaaatgat gctacaatag aagcttctgt tataggatat ctaaataatg
    26401 gtgatgaagt agaagtttta gatgtgttaa aaactggatg ggtagaaata aaatacaatg
    26461 aaggtattgg atatgttagt gggtcttatt tgacaaataa taagcctgat aatagtaatg
    26521 aaaatataaa aataaagtat gtaaaagaaa aagatggtct aaatgttagg aaaggaccaa
    26581 gtacagaaga tgaaaaaata ggtcaccttt catatggaag caaagtagaa acaatagaaa
    26641 tgtttgctac tggatgggta aaaataaagt ataatggtgg atatggttat gtaagtaatg
    26701 attacttatc tgatacacca gttatttaat tataagtaac aataaaaaaa ctgctttaat
    26761 ttgtaaagca gtttttttat aaaaatttaa gtctaataac tatttctatt ttgatacctt
    26821 aatcctggga tttattatta tggatattat caacatacaa acactccaaa tccagtgtct
    26881 aattccaaac ttagatatta ataaattcag tcctgctatg gtaaataagc agtatttaat
    26941 tacaattaaa agtgtattta tagaaagccc cttcatagaa agtatcctaa atccaataat
    27001 agacattcta agtcctataa atgccaataa tatacctgca atatcctgaa ttaagtaata
    27061 gtattcaaat ttcatattca atcaactctt ctctgagcag tatcaaatat ttctaactct
    27121 tcaatttcat catctgtgta tgtaagcata gtaaaaccag ttacaccata aataaatgaa
    27181 attataggtg taatccaact taagaaacaa tatggaataa attctagtgg gcttacacca
    27241 agagtctgag cacagaaaac agcatttgaa ttccatggta ttaatggacc accaagtgta
    27301 gctgtatctt ctataattct agatagattt tgtggtttta atttaaattc tttgtatatt
    27361 ggagacatta gagttccgac aaatacagaa gtgaacatca ttgatgaact aaatgcattt
    27421 gcaaagtaac ttactataaa agtagaccca accaatttag ttcttgattt tcctatttta
    27481 gttataagag gttgaagcag tacttctaag aatccagttt tttggagaat accagcaata
    27541 acgaaaacta caaatactag taaaacggtt tcagccatac tcattattcc accacgattt
    27601 aatagtttgt cggcatagac aaatccagta tctatagtaa atcctgatag catgtaattt
    27661 aaaacatcac ctattttttc tccttcttga aatactgcta taataagtcc catgatagct
    27721 gaacttagta tagatataat gggtggcttt tgtagcaata aaagtaataa taaaaatatt
    27781 attggaatca ttgctactaa accaatatga aagtttgaat ttaatacatc cttgatttga
    27841 tttatttgaa catagtctat agtattattt gaatacttaa atccaattac tgtatacaga
    27901 actatacata ttacgtatgc aggtcctgtg gtataaaaca tatgcttcat atgtgtaatt
    27961 acatctgtct tacaaactgc tgcagctaag tttgtagaat ctgatagagg tgacatctta
    28021 tctccaaaga aagcaccaga aatgactgca ccagctgtta aaccaagagg aatacccata
    28081 ctagtaccaa tactcatcat tgctatacca gaagttccaa gagtccccca agatgtacca
    28141 gtagcaacag aagttaatga acatacgatt aatgttgtaa gcagaaaata tttaggggtt
    28201 attattgtta gtccactata tactactgtt ggtattgtac cagcagctat ccaagctgct
    28261 attagtacac caacagaaag tataattaag tttgattgaa aggcatcttt accaacttca
    28321 aatccaaaag cttctatttc atcattagta taaccaagtt tcatagctgc aggaactact
    28381 ataagccatg aaagtaaaaa cattgtagtt atagaagcat taaatacaac tataccaact
    28441 gatgttagag ctattattgc aagcattact aacaaggaat atctaaatga aggtattttt
    28501 ctttctgtat tcattttcat agtgcaaatt ctccttaaat atttttagtt aattgcattt
    28561 tttattctta taagagcttc ttcaagcata cttcttggac aagctaagtt tattctttga
    28621 tacccacttc ctccaatgcc aaagctgttt ccttgattta gagcaacttt acctttttgt
    28681 acaagtatac tttctagttc ctcatcactt aatccaagtg cactaaagtc tacccataat
    28741 aaataagtac cttctggttt tctaacttta agttttggca tattttcatt tatatatttt
    28801 atagcaaaat ctatattaga ttctaaatat tctaaaaatg attctagcca agattcacca
    28861 ttattatatg aagcttcagt tgcaactaag ctaaagcaat tatttctctt tatatcaatt
    28921 ctggtaaagg catcatctaa caatttatag tctttttcat caggtagtat tacatatgat
    28981 gattgaagac cagctatatt aaaagtttta gttggagcca tacaagtaat tgtatttttt
    29041 tcaaattctt tagaaataga tgccatagga atatgcttat gtttttttaa tataatgtca
    29101 ctatgtattt catcagatat gatttttaca ttatgcttaa gacaaatatc tcctagtttt
    29161 tttaattcat cttttgtcca tactctacca actggattat gaggattaca aagtatgaat
    29221 aattttacat ctttaatctt gttttcaatg tcttcataat ccattatgta gtttccattt
    29281 tctagttttt gtaatgggct tataattagt tctctattgt tattttttac aacactatta
    29341 aaagggctgt aaactggttc ttgtatcatt attttatcat ttgcttttgt gagttcattt
    29401 attaaaagac ttatagctgg gataacacct ggactataaa ttaaccactc actttttatt
    29461 ttccagttat gtctcctatc tagccagttt actatagatt cattgtaaga atctggtctt
    29521 gttgtgtagc cataaatctc ttgttctagt ctatttttta aggaatcaat tatacaaggt
    29581 gcagccttaa aatccatgtc agccacccac ataggaagta aatcattagt tccatacttt
    29641 ttttccattt ctgaccattt agatgaaaaa ttattgcttc tatcaacaat ctcattaaaa
    29701 ttataattca ttgtaaatac ctccagtaat tttaatttta tgttaataat attaagcaaa
    29761 caacgtgcca atattgataa taaaaaatat ttattcacaa gttaatattt aatattaagt
    29821 aatttcagag catagataag ataaaaatat taattatact taaaactttg tggaaaaggt
    29881 tatttctaat aaatttttaa atatatgaaa atgtaattaa ataggttaaa taggtttaac
    29941 tgtttaactt gttagaccta tttatatttt ttagaaattc tactcctttt gatgttataa
    30001 ttgaacctcc acgaccaaca agtatgtcta caagcccaaa gttttgtagt tctaaaagca
    30061 tatttctaat ctgttgttct gtcaaaaatc tattttcctc taaagctatt ttacataagc
    30121 tttttctacc tattctttct tttaaatcat aagccttttt taaattatcc aatataaata
    30181 tgtattcatc tagtgacctt ttaaaattat agtcgtattt catgatgttt ttgtctttgc
    30241 caatgttgaa ttgatacttt tttatattat cacttacttt attacaaacg gttctactat
    30301 aatttgaatc tatagtatct aatatatatt caggtaaatc acatatttct ataatatctt
    30361 tttccaagta acagaagtat tctcctaagt ttcttaattc tcttacattt ccttcccatc
    30421 tatacatttt aaagatttct tttacttcct cacttagaat aaaattacat ggaatatcat
    30481 attttaatga accaaaaatt tcaaatatat cagcaggtct ttccctaagt ggatgtattt
    30541 taaggggaag aacattcaac ctaaaatata aatctcttct aaacatattt ttagatacaa
    30601 gttcttttaa atttctatta gtagctgcaa ttattcttac atcaatgtca atgacattat
    30661 tagaaccaat acgtcgtact tgtttttctt gtatgactct aagtaattta gattgagaat
    30721 ttaaatccat ttctccaatt tcgtctaaaa atatagttcc attgttggct aattcaaata
    30781 aaccaatttt cccacctttt ttagcaccag taaaagcccc ttcatcatag ccaaataatt
    30841 cactttgcag tagattttct tgaaaagtac tacaatttac tgcgacaaaa ggaccatctt
    30901 ttctcctaga agcactatga atggattgag caaataattc tttaccagta ccactttcac
    30961 caattataag gatagatgaa tttgattgag ccattttatt agcaattttt tttgtattaa
    31021 tagtttgtat actagaacct aatatgtcat caaatgtgta tttactgata ttaccagagt
    31081 ttactagttg tgctcttaat ttagcttgct ttttttctaa ttgagaaaac tttgtcatct
    31141 ttagtataaa tccatcaaat acatttaatt gtatatgttt aatctctaaa tttatatcaa
    31201 tatgatttat tttaatcaat ttctcaaaaa atggagtttt attggtcaat atgctttgaa
    31261 aattgatgtc ttttatgcaa tcaccaacaa atgagtcaat catttcattt gcatttatag
    31321 acaaaatttt tctagccata tgattataga attgaattat tccatcgtta tttgtgcata
    31381 taattccatc atcaattata gatagcaaca aatcaaattg tctttcaaac ttatttgcat
    31441 ctaacaataa ctcacctgta ctataacttg taggaattat tttttctacg tattttttta
    31501 ttaggtcatc ttttattaga tgttttaatt tggtttttgt agcaatttca acaatacaac
    31561 ttaaatctat tattctgtat tttaaatcta taacttcaca atttttaaac ttaggcaaga
    31621 ttttttcgcc aggagttagg attacagcat ctgtgggagt aaactcaatc tctggatagc
    31681 agggcaggat atttatattg tctattccta atctatgtat taaagaaatt gtttctattg
    31741 ccatatcttt acttaagtta tatacataaa taattttatc tttttctaat ttggatatca
    31801 tatcaatact gttcttttca aatgtcaact taggaacaat gatttgagca tcatagtgag
    31861 ataattttac tatttcatca tattttaaat aagcagatag gagtataagt ttttctttaa
    31921 aaaactttaa atttccctct tcaaatgagt ataaatttat ctttagatta tcacctaaga
    31981 attgccttat ttgattttca taaatttctc cagcgtcttt ttttaaactt acaatagcta
    32041 attccatttg tttcatttta acctctcata caaatttgac ttattttaga ttacataata
    32101 attaaattag attaaataat attatttaat tattattata aatttattat agactacaca
    32161 ttgaagtaaa agaagtagct aaaattattc cttttatttt tgttttttgt atctatttgg
    32221 tataatagta ttagagcgta taataattta ggcaaaattt tttaaggaag actagaggag
    32281 aatataaaat gaaaaaatgt ctttactgta atagggatat aaagtcacca aataataaat
    32341 tagctataaa atatgatgac aatatgaata tatatccatg tcgtgcagaa tgtaaggaaa
    32401 aaattgaaga atatatagca aaaaaaccta catataagtt tataaatata ttagaggttc
    32461 ttttaggtgt gggcggaata ttctgctttt tgagtaaatg gactattgca gcccaagttg
    32521 tacttggaat tgatgcactg gttatatttt tattcccatt ggcaggattt aaaatgaatg
    32581 gaaagttaag tatggaacaa actaagaatc aaagtaggtc tattgcaata tcaattttgg
    32641 catttatagt aataataact gtattatatt ttaaacaagt tggtaagtag agcataattg
    32701 tataagacat cattagagta tgaggtgagt ttatggaaga aagaaaatta gcaccaaaca
    32761 atgagaggga agctctcata aaaagattaa aaagaataga aggtcaagtt aagggtatac
    32821 aaaagatggt ggaacaagaa cgttattgtg ttgatatatt ggttcaaata tctgctataa
    32881 ggtctgctat aaatagagta ggcacaatta tcttagagaa tcatataaaa ggatgtgtag
    32941 cagaaagtat taaacatgat gatgctgata aaactgaaga gatgataaaa gagcttatgg
    33001 atactataaa taaatttaca aaataaggag gcggttagtt atgaatcaac aaggatttat
    33061 tatggaaatt gttgatgata gaactgcaaa gttaaaaatg caaagacatt cagcttgtgc
    33121 tgcttgtgga aaatgtgcta ctacaaattc agcagagtca aaagaaatat tagtagaagt
    33181 agacaacaca attggtgcaa aagttggtga ccatgtagaa gtgagtatgg ataatatgaa
    33241 tgtattaaaa gcagctgtaa tggcttatat aatacctctt atagcacttc ttgtaggaac
    33301 aatagggact tattatatat tgggggcaat tggaatgaca actggagttg aagccataag
    33361 tggattagtt ggaatttgtc ttacaataat ctgttattta tacttaaaga agaatgacaa
    33421 aaaatttaga gacagtagag aatttatacc agtaataaca agaatattaa ttgaccttta
    33481 agataattat aattaaaaaa tagcaatgta ctttttaaat aaatactcaa tacgtatttg
    33541 tagagtttaa gtacattgct atttttatat ttttattttg attttctgta aggaataaag
    33601 ttttttctga tttttaaaag attcaatgtt cttacaaaag aagttacaac taatacacca
    33661 agtgctattg cagcacttag aaatagcgca tctgtacctt ttgacatagc caaagaataa
    33721 tttttctgaa tcaaagacaa cattgtatta tatagcccaa ttcctggtat tagaggaaga
    33781 atacctggaa ttacgaacac aatagctggt tgctttagtt ttcttgctaa agtctcactg
    33841 cacgctgaga ccaaagcagc agcgataaaa cctgcaaaaa ctgcatttgt agtaaaatta
    33901 aataaataaa catatacaat ccaaccaatt ccgccagtta ctccagctgg aagaagtaga
    33961 tatagtggag cattaaagaa aacagcaaat ccagcagttg caacacctga aaataaaaaa
    34021 tgcaaaatca tagacatatc agtcattaga aaggacctcc tattctatac catgtatcaa
    34081 ggacaaaacc aactccagaa gcaattgcaa taataatcat agcagcatca aaagcacgag
    34141 aaattcctga tattaaattc cctgatatta aatctctaat agcttttata aaagcaactc
    34201 ctgggagtag tggcattata gcgccgacta taagcatttt agggtcatct aaaatgccta
    34261 tttcaactag tagaactcct gaaagtgcaa ttaaaaaaga agatactaaa caggaaaatg
    34321 cagatattgc acttatcttc atcgttttat cataagtaat tgcagcaaag attgctatta
    34381 taaacgtaag tataaaattt aatacataat tccctccaag caaacaagca aaacaagcag
    34441 atgcaattcc tgtacaagag taaaataacc ataaaggata aggttttaca tcttggattt
    34501 cataaagacg tgcaatggca ttatcaatat catactcttt gtcactaaca aattctcgag
    34561 aaaaactgtt taataaagaa atcttattta agtttatacc tcttgattga atcgttttca
    34621 taaacgaaaa gccatcaaat ttctcatctg aaataattat tactgtagga gttgtaaaaa
    34681 tatttacatg ataaaaccct cttgacctgc atattctaag gacactgtct tcaaccctag
    34741 atgtttcagc tccatttttt atcatcagtt cccctacaaa tagagctagt tttagaatat
    34801 ttttcttata ttcaagttcc tcattttgat tcataaatac acctccaaat taaaaaacgt
    34861 aatattgaaa ttatatcaaa tttttaagta atattcctta atatctatac aaatatatta
    34921 tctttttttt gtttcaaaat agtcacattt aaattatatc caattaaaag aattagacaa
    34981 tattatttat tatattttaa cttaaaaata aagaaagtaa ctatgttaaa tatggaaaaa
    35041 tggcaaaaca cttgactatt aattggtaaa ggactataat aataaattat catattgata
    35101 aaaacgaaaa ttatgaaatg tctgtaaaaa taaaatttaa ataataacta ggaggagtaa
    35161 tatgtttgag aacttgaaaa aagcggaccc tgagatttat gaaagtatga aaagagagtt
    35221 aaaaagacaa caaagaaata ttgaattaat agcatcagaa aacatagtat cagttccagt
    35281 aatggaaact atgggaagtc atcttacaaa taagtatgca gaaggttact caggcaaaag
    35341 atattatggt ggatgtgaat acatagatga agttgaaact cttgcaatag atagaatcaa
    35401 aaaaatattt ggagcagaac atgctaatgt tcaacctcac tctggagcaa atgcaaatat
    35461 tggtgtatat tttgctatgt taaaaccagg tgatgttgtt atgggaatga atttatctca
    35521 aggtggacat ttaactcatg gtgctccagt taatatttct ggtcaatatt ataaatttta
    35581 tgaatatggt atagataaag acagtggact tatagatttt gatgaagtta gaaagatagc
    35641 acatgaagta aaacctaaaa tgatagttgc aggagcaagt gcatatccta gagaaataga
    35701 ttttaaaaag tttagagaga tagctgatga ggttggagca ttgcttatgg tagatatggc
    35761 tcatatagca ggtcttgtgg ctgctggtct tcaccaaaat ccatgtgaag tggctgattt
    35821 tgttacaaca acaactcaca aaactttaag aggacctcga gggggtgtta ttctttgtaa
    35881 agaaaaatat gctaaagaca tagacaaagc aatattccct ggtattcaag gtggacctct
    35941 tgaacatata attgcttcta aggcagtttg ctttaaagaa gctttaagtg atgagtttaa
    36001 agaatatcag gtacaagttg ctaaaaatgc aaaagcctta gctgaagaac ttattaaaag
    36061 agattttaaa ttgatttctg gaggtacaga taatcattta atactattag atttgactaa
    36121 taaaaatata actggtaaag cagcagaaaa gagattggat gatgcttata taacagctaa
    36181 taaaaataca attccatttg acccaaatgg tgctcttatt acaagtggaa taagacttgg
    36241 tactccagct gtaactacta gaggtatgaa agaagaagat atggcaataa tcgctgaggc
    36301 tatagaccta tgtttaactt atgatgaaga atctaaggct agaacattgg ttgttggttt
    36361 aactgaaaaa tatcctttat atgaagaata taatattatg gattaattat aaagaacaac
    36421 taaataaaat acatttaaat aattacaatg attgtgtatg tatttgaata tagttagata
    36481 taaaaaaggt gtctcaaaat gaacttttta gtttatgagg cacttttttg tatggaatcg
    36541 aacatatttg tgttatttaa ataataaaaa atatggttat ctctattttt agatggtctc
    36601 tttgtatttt ttaattaaaa ctttaagatt tcttaagaat tatactaggt ttttctaaag
    36661 atttaaagtc tatacttata agtatagtaa tcatatgaaa agaaaagctt taacgaggag
    36721 ggaatcttat gaaggtatta attcttacag gaaaatttgg tatgggtcat tactcagcat
    36781 caaattcttt aagtgaagat ataaaagcaa aatttgataa ttcagaaata ataattaaag
    36841 atatatttga gtacattatg cctaactatt cagataaaat gtacaagact ttttctattc
    36901 ttgtaaatcg gggaagtagt ctttataatt tattttataa atgtgctgaa aatggaaaga
    36961 aagatataaa atttactttt tcagattatt ttttaaataa attagataca ttacttcatg
    37021 aagtacaacc aacagtagtt atttcaactt ttccattttg ttctcaatta gtatcaagat
    37081 ataaggaaaa atataactca aatcttcctt taataacatg tataactgat ataagtagtc
    37141 actcagaatg gattagtaaa aatacagact gttatttagt agctagtaaa tctactaagg
    37201 aagaacttgt ttttaaagga atagatgaat ctaagattaa agttaatggt attccagtaa
    37261 aaaaagaatt taaaagaata gaacatgtaa atcattcaac taaaaaaaat attcttataa
    37321 tgggtggagg attaggatta ctgcctaaat cagaacaatt ttacaaagaa ttaaatagtt
    37381 tagaaggagt aaaaactact gtaataactg gtaataataa aaaaatgtac tataaactat
    37441 atggtagata tgaaaatata gaggtagtag gttacaccaa tgaagtatat aaatatatga
    37501 aagattctga ccttattatt tctaaaccag gtggaataac actatttgaa acaatttatt
    37561 cagaacttcc aatattggca tttaatccat ttttacaaca agagatagat aatgctagtt
    37621 ttatattaaa taatgaaatt gggagaatac ttggtaaaaa taaaaaatac tatgtagatg
    37681 agataaaaga tttaatttat gatgatgcta ctcttaaaga aatgagcagt aacatgaaag
    37741 aattaaaaaa acaatttgat aataatacct tagagaatat tttattttca cttgatgaac
    37801 aaggagcgtg tagagaatgt atgtagtagg tttaattatc gttgttgcat tgattttttt
    37861 agtccattca attataccta catactataa taaactatta aataaagagg tattaaaaaa
    37921 tatggctgga gaaaatgaaa ttgcacttac atttgatgat ggtccagata agagatatac
    37981 agaaaaatta ctagatgtgt taaaagaaaa tgatatacaa gctatgtttt ttgtagtagc
    38041 aaagaatgct gaaaaagagc ctgaaattat aaaaagaatg ttgagagaaa atcatatagt
    38101 tggtttacat tcattggaac acagaaatgc atggctttat agttatagtt atgttaaaaa
    38161 agattttatt gaaagtacaa atataatgaa aaatttaggt gtagatgtaa actactatcg
    38221 tccaccatgg ggtcatacta atatattttc aaattcattt gttaaaaaat ataatctaaa
    38281 aatgactttg tgggatgtaa tggcagaaga ttgggagaaa gatagtacag tagacattat
    38341 tataaacaag ttaatgagta gaacaaaaga aaattctata atttgtttac atgatgcagg
    38401 tgaaaattca ggtggtgcag taggtgcacc tgagcgtact attgaagctt taaagatagc
    38461 tattccaaaa cttaaagcca gtggtttaaa gttcgtaaca ccagaaagga tgtagttatg
    38521 ataagtaaaa ctgaaaagaa aaataaatgc ctaggtagtg tagctttttt agttttacta
    38581 atgggcataa caggatattt tgtttttaga gggcagtcag ttgaatcatt gataaaatca
    38641 ttaaaaggtg caagccctat gtttatacta attggatttg caatgatgtt tatatatgtt
    38701 gcctgtgaag gtataaatat atacttaggt atgaaagctt taaaccaaaa gactactctt
    38761 ttaaaatgta tgggatatgc ttttattgga ttttatttta gttctattac accttcagca
    38821 tcaggtggtc aaccagcaca agtttattat atgaaaaaag acgatataaa tatatcatat
    38881 tcttcactta tactattagt cattgttgtt attcaccaag tagttatact ggcatatagt
    38941 ggaataatgt tcattatgga acgtgagttt atattaaata atgtaagtgg tatgaacatt
    39001 ttactaatat atggtgtaat aacaaatgtt gctcttgtca ttggagtaat tgcaattata
    39061 ttttcaaaaa aacttgtaaa caattttata atatcaataa caaatttatt aggtaagtta
    39121 agaataataa aagatgttga aagttcaaga aaagttataa tatctcaaat tgaagagtat
    39181 gttaaaggtg ctcaatatat aaagcagaat ccaaaacttg tagtccaaat tttagtcata
    39241 actattgtac aaataacagc tatgttttta gttcctttct ttgtatacaa agcttttcat
    39301 ctatcaacat atactgtatt tgagatatta gcgatacaat ccttgcttaa tattgctgtt
    39361 tcttcattac cattgccagg ggctgttgga gcttctgaaa atagttttat gacattattt
    39421 aagatatttt tccctggtca cttattagtt ccggcaatgt tacttagtag gggaataagt
    39481 ttttatgcat ttgtagctat aagtggattg atatgtatag tagtacatgt aaaatcttct
    39541 gaaaaagtaa aagcagtgaa aaaagttgct tatgtaagat aatattatat agattatttt
    39601 tattaatatg tcaatttgtg tgtatatttt aattaagctt taaacatatt tacaggagta
    39661 gaaactatta aaacgtgtga cattgctaag cttttgctaa taaagtataa tattttatat
    39721 agtttgaaat atttaagaaa tatagcaaaa aaaggagctt ggtgatgaat aaagagattc
    39781 caaaaaaaat tttagtagct gatgataatc ctgagattag ggaaatcgta gaaatacttt
    39841 taactggtga aggttatgaa gttattatgg caacgaatgg agaagaagct gtaaacttag
    39901 tagatagtac gattgatttg attattttgg atgttgtaat gcctgtaaaa acaggatttg
    39961 ttgcatgtaa tgaaattaga gaaaaaacga cagcaccaat attattttta actgcaaaaa
    40021 ctcaagactc tgataaagtt attggatttt cagcaggagg agatgactat ttatcaaagc
    40081 ctttttcata ttctgaacta atttcaagag ttaagtctct acttagacgt tattatatat
    40141 accagggaaa ggaaaaggaa agagagccaa atatattaaa aacaaaagag ttatgtgtca
    40201 atttagatac tcaagatgtt acactaaatg gagaacctgt gtttttgaca actatagaat
    40261 atagtatatt aattcttatg ttgaaaaata gaaaaaaagt tttttcgtct gaaaatttat
    40321 atgaaactat ttgggatgag cagtattttt atacagcaaa taatacaata atggttcata
    40381 ttagaaattt aagaaaaaag ttagaaaaag accaaaaaaa tccacaatat ataaaaaccg
    40441 catggggaaa ggggtattat attgattaac aaaattaagc catctaagtt gggagttata
    40501 ctattgatat atgtagtaat ctcagctgca gtggctttca ttttaaatat accattttac
    40561 tctgctgttg aatctatagt aaaagatgta tcagaaggga aagtatattt taaaagagaa
    40621 gtaaatcaac ttatggataa ttttcaaact tatgtgaata acaatggtat aagagcagat
    40681 gatggagatg atatagcaaa atggaatagt gataattggt ttgtttctat gaagatatat
    40741 aaaggaaata aggtttttta tgatacatta tactatccta atgaagtacc tgataagagt
    40801 gaggaaaatg agttttatag cagtcccatg gctagaaact atgagataca attttctgat
    40861 attaaagcta atatagttgt agtagcttta tttagattta gatttcaaaa ttttatagaa
    40921 gcaatttcta ttacatttat ggcacttaca tttattataa catttttact gttgtttagt
    40981 agaaagataa agtacctaag gaaaatagaa atgggtataa agatagtaga gagtggcagt
    41041 ttaaagtata gaataccagt aaaaggtaat gatgaattat catcacttgc atctagtatt
    41101 aatgagatga gtcatacatt ggagaatcaa cttataaaag aaagggagat gaagaataaa
    41161 aataaagata tagtaacttc aatatcacat gatgttagaa ctccattaac gtcagtaatt
    41221 tgttatttag atttgattaa agaccataaa tacaatagtc ctgagcaatt ggaacaatac
    41281 ataaaaaatg taaggtctaa agcatatcaa ataaaagatt taacagatga cctttttacg
    41341 cattttgtta attctggaga ggaagtttca aaagggtatg aaaaaataaa tgctaatgaa
    41401 tttatttttc aattactttt agatagttca tatacattgg aggagaaagg atttcatata
    41461 acaatagaaa atgaacttta taaccaatat catatttatg tagatgttac acaatttaga
    41521 aggatatttg ataatttatg ttctaatata ataaaatatg ctaggaaaga taagcctata
    41581 gtatttttaa ttaaagtaga ggattctaaa ttactaatta tacaaaaaaa tagagtaagt
    41641 aatttttcta agaatgtaga aagttttgga attggtataa agaattgtga gaaaatagtt
    41701 gcatatcata atggaagcat aaatgtaaat tcagatgata aagaatttgc tattgaaata
    41761 tctattccag caaaagaatc ataaaaattt aaattatata ttgtgtaatt gctattatat
    41821 attgtgtaat tgcttatgta aaattctatg aagcaggaag catgtgactt tagttatggg
    41881 atgttcaata ttgtgtacct ctaggcaagt aacaagttta cttacaagac catataatat
    41941 tattatctta aaaaaagggg acataataat atggttttga caggagcaca ttatatttac
    42001 attctattta tggtaattat attaattact atgattatga aaaaggatac aatagtacca
    42061 tgtatattag gtgttttttt tatggggttg ttctttgaaa aaaacatttt tggtgctata
    42121 acagcagtgt ttaactcttt tattatatct ttaaatgagt tgggtccaat tatcttgatt
    42181 atagctatta tggttgcatt atctaaagcc ctagaagcca ataatgctat acagtatatg
    42241 gtgagaccat tttcgagagt tataaaaaat tctaatacag cattttttgt aactggattt
    42301 gttatgttag ttctttcttg gtttttctgg ccaactccag ctgttgcctt agttggagct
    42361 gtatttttac ctgttgctat gagagctggg ctaccagcaa ttggtgttgc agtagcatta
    42421 aatttatttg gtcatggtct tgccttgtct acagactttg ttattcaagg agctccaagt
    42481 ataacagctg gtgcagcagg tgttgcagta tcatatgtta taaatgatgg tatgattttg
    42541 ttttgggtga tgggaatcgt aaccatatct atggcatttt atacattaaa aagagatatt
    42601 aacaaaggaa tgtttagaga agaactaaaa ggttttgaaa gtgaagaagt agaagagttc
    42661 aatggaaaat ctaaaatagc aactatttta gtagctctgg gatttcttgc tgatataatt
    42721 gctatgtata tatttgacct aaaaggagga gatgcatcag ctcttttggg tggaacagca
    42781 gtatttttaa taataattat aaatgttata aattttggca aagatagtct tgaaaatgta
    42841 tgtgagaata taattgatgg ttttgtgttt gggataaaaa tatttggagc aattatacca
    42901 atagcagcat ttttctatat gggtgaagtt gcaccattga caggtgtatt tggaaaagta
    42961 ttagcaccag gttcacaagg tttattatca gatataggca tagctctttc tcaaacaata
    43021 ccacttaata aatttgccgt atcaggtata gaaactgtag tgggagcaat aactgggctt
    43081 gatggttctg gattttctgg gatttcatta gttggttcac ttgcctctgt atttggaact
    43141 gctataaatg caagtgttgg tgcactagct gcattaggac aaatcagtgg tatatgggta
    43201 ggtggaggct gtctagttcc ttggggtctt atttcagcag cggcaatttg tggagttagt
    43261 ccaatagaat tggcaaagcg aaactttgtc ccagttataa ccggattggt tgtaacaacc
    43321 atagtagcaa tgtttattat ttaataaatc gaataaatct ttaattgtat aaattaaaaa
    43381 tagatgtgta gctataattt attataattg ttttactaat tctaagccat acatctattt
    43441 ttattgatat ttttattagt attctttaat aaaataatat ttttcattat actatacata
    43501 acatctaaat ataacatcta aaatactgtt atctatattt aatatcttgc caaatttttt
    43561 gatgttttat tgccctgtcc caccaacata tataagctat cacaagtttt tacctatact
    43621 atcaccaaac aaaaattcta attttaattt attattttat aacctatatt atattaacta
    43681 tattagtttg tagactttag atgtaattat aaatattaat actccaagag ttcaaattca
    43741 tatcctagtt ttcttgcatt tgatataaaa tcatttaaaa tttctgtact agttttggaa
    43801 actgcatgta gtaacaagat agaaccatca tgtagattat ccattatttt ttgcgttgct
    43861 tcttcatgtg atggttgttt atcagtatcc cagtctctgt atgcaaaact ccaaaataca
    43921 gtcttgtatc ctaaattttt agtcattgcc aagctttttt ctgagtattt tcccatagga
    43981 ggtctaaaaa atttaaccat atctttccca gttacatctt tatataactt ttcaacatca
    44041 tataattcgt cattaaagtt ttttagattg cttgtttttg ttggcataga tggatgggtt
    44101 ttactatgat ttccaactat atgtccctca gaaaccattc tttttactaa atctttattt
    44161 tcttttatat atggagctgt aacaaaaaaa actgctttaa cctgattttg ttttagagtg
    44221 tcgagtattt ttgtagtgta tccattttca taaccttcat caaatgtaag atatagtgtt
    44281 ttttgaccat cttttgtagg tccattgtat agggcatcat agtcagaaaa tttaaattca
    44341 atgtccgtat ttacttctgg tgttttatgc ttattgtttg gtatataaaa ccaatcaaga
    44401 gtagtgttat ctaaagaaga tacatctaat ttattattat cattattagt agtggctttt
    44461 gatggtttat ctgttccgtc tgaaactatt acattggaag tatctttacc actatctatt
    44521 ttttccttat cttcttgtaa ctgtgtttcc ttattttgat tttcgttttg attgttttgt
    44581 gaatttgaac atccaacaat aaaaaaaata gaaatagaaa gtagtgttaa ataatgcaat
    44641 acttttctaa acattttgaa gctcctttct aaattaataa taattgcata taataataat
    44701 tatatgatta attacaattg catatagtat tattataatt ggaaattact attaataata
    44761 gttatatctt taaaaataag gtcacaatag tatgacaaag ggtgaataat caataaattt
    44821 aaaaaaaaat gaaaaaaata gttgaccata ttatgagaag atgttattat aataaatgtg
    44881 ctcaacaaga agtaacaaaa taacaagcac aaagaagtta attgaat
//
LOCUS       DAMJWC010000030        44680 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMJWC010000030 DAMJWC010000000
VERSION     DAMJWC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44680
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.030"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            514..768
                     /locus_tag="PC503_001868"
     CDS             514..768
                     /locus_tag="PC503_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527841.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            804..1127
                     /locus_tag="PC503_001869"
     CDS             804..1127
                     /locus_tag="PC503_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527842.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1401..1553
                     /locus_tag="PC503_001870"
     CDS             1401..1553
                     /locus_tag="PC503_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527843.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            1747..2670
                     /locus_tag="PC503_001871"
     CDS             1747..2670
                     /locus_tag="PC503_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDF2527844.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVRA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   2937..3752
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2937..2965
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            3943..4095
                     /locus_tag="PC503_001872"
     CDS             3943..4095
                     /locus_tag="PC503_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527845.1"
                     /translation="MKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4215..5028
                     /locus_tag="PC503_001873"
                     /pseudo
     CDS             4215..5028
                     /locus_tag="PC503_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5080..5241
                     /locus_tag="PC503_001874"
     CDS             5080..5241
                     /locus_tag="PC503_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527846.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(5569..6033)
                     /locus_tag="PC503_001875"
     CDS             complement(5569..6033)
                     /locus_tag="PC503_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527847.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(6169..6486)
                     /locus_tag="PC503_001876"
     CDS             complement(6169..6486)
                     /locus_tag="PC503_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527848.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(6769..7065)
                     /locus_tag="PC503_001877"
     CDS             complement(6769..7065)
                     /locus_tag="PC503_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527849.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            complement(7084..7497)
                     /locus_tag="PC503_001878"
     CDS             complement(7084..7497)
                     /locus_tag="PC503_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527850.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7481..7714)
                     /locus_tag="PC503_001879"
     CDS             complement(7481..7714)
                     /locus_tag="PC503_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2527851.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            7933..8307
                     /locus_tag="PC503_001880"
     CDS             7933..8307
                     /locus_tag="PC503_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2527852.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            8919..9611
                     /locus_tag="PC503_001881"
     CDS             8919..9611
                     /locus_tag="PC503_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527853.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            9807..11867
                     /locus_tag="PC503_001882"
     CDS             9807..11867
                     /locus_tag="PC503_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2527854.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12072..12395)
                     /locus_tag="PC503_001883"
     CDS             complement(12072..12395)
                     /locus_tag="PC503_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF2527855.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12388..13089)
                     /locus_tag="PC503_001884"
     CDS             complement(12388..13089)
                     /locus_tag="PC503_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF2527856.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13367..14752)
                     /locus_tag="PC503_001885"
     CDS             complement(13367..14752)
                     /locus_tag="PC503_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2527857.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(14860..16098)
                     /locus_tag="PC503_001886"
     CDS             complement(14860..16098)
                     /locus_tag="PC503_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2527858.1"
                     /translation="MELFIEVIKFNIYISPLILFFILFTKKISKYTFKFNYFICLLIV
                     VRMMFISKINLNILNINNTTINIYKHNIDNYIPYDQGITLDIFMYIWILGIIAISFYY
                     LRTNFKFYNYIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTR
                     CKIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIYWFNPILYLLKKYFH
                     ELCELSCDEIVIDKCTTSEIKEYAYIILDTIKYQKSLKYSSFVSQFLNKKNIILKKRL
                     DSMFNQDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGT
                     HIIDSNGNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFK
                     KTIPLYDKEGIKIIGRFEIN"
     gene            complement(16111..16479)
                     /locus_tag="PC503_001887"
     CDS             complement(16111..16479)
                     /locus_tag="PC503_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2527859.1"
                     /translation="MKKIPKSELLVMNFIWDKDIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(17007..17429)
                     /locus_tag="PC503_001888"
     CDS             complement(17007..17429)
                     /locus_tag="PC503_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF2527860.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            17907..20810
                     /locus_tag="PC503_001889"
     CDS             17907..20810
                     /locus_tag="PC503_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2527861.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEDEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDESLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            20843..21289
                     /locus_tag="PC503_001890"
     CDS             20843..21289
                     /locus_tag="PC503_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527862.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            21412..21714
                     /locus_tag="PC503_001891"
     CDS             21412..21714
                     /locus_tag="PC503_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2527863.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            21895..23301
                     /locus_tag="PC503_001892"
     CDS             21895..23301
                     /locus_tag="PC503_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2527864.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPVITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            23645..24703
                     /locus_tag="PC503_001893"
     CDS             23645..24703
                     /locus_tag="PC503_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2527865.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVNIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            24802..25488
                     /gene="araD"
                     /locus_tag="PC503_001894"
     CDS             24802..25488
                     /gene="araD"
                     /locus_tag="PC503_001894"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF2527866.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            25506..26153
                     /locus_tag="PC503_001895"
     CDS             25506..26153
                     /locus_tag="PC503_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2527867.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(26326..27693)
                     /locus_tag="PC503_001896"
     CDS             complement(26326..27693)
                     /locus_tag="PC503_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF2527868.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(27883..27971)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            28399..30519
                     /locus_tag="PC503_001897"
     CDS             28399..30519
                     /locus_tag="PC503_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF2527869.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRLFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            30623..31876
                     /locus_tag="PC503_001898"
     CDS             30623..31876
                     /locus_tag="PC503_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF2527870.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVIAMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(32030..33091)
                     /gene="ytvI"
                     /locus_tag="PC503_001899"
     CDS             complement(32030..33091)
                     /gene="ytvI"
                     /locus_tag="PC503_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2527871.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            33365..34105
                     /locus_tag="PC503_001900"
     CDS             33365..34105
                     /locus_tag="PC503_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF2527872.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            34117..35895
                     /locus_tag="PC503_001901"
     CDS             34117..35895
                     /locus_tag="PC503_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2527873.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            36062..36979
                     /gene="pfkB"
                     /locus_tag="PC503_001902"
     CDS             36062..36979
                     /gene="pfkB"
                     /locus_tag="PC503_001902"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2527874.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     IFKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            37016..38935
                     /locus_tag="PC503_001903"
     CDS             37016..38935
                     /locus_tag="PC503_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2527875.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            39531..41057
                     /locus_tag="PC503_001904"
     CDS             39531..41057
                     /locus_tag="PC503_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2527876.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            41085..41642
                     /locus_tag="PC503_001905"
     CDS             41085..41642
                     /locus_tag="PC503_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527877.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            42164..43201
                     /locus_tag="PC503_001906"
     CDS             42164..43201
                     /locus_tag="PC503_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527878.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNQILTKVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQVE
                     SEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAINL
                     YTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKSEW
                     SYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYDEY
                     FKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTKVG
                     RNFIRYSLRSI"
     gene            43312..44454
                     /locus_tag="PC503_001907"
     CDS             43312..44454
                     /locus_tag="PC503_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2527879.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT        17869 a         4695 c         7292 g        14824 t
ORIGIN      
        1 tgaaactcac gatagagata taaatgcaag tataaatata ttaaaagaag gattaagact
       61 aataacaatt caaaataaat aacgtatgta agaaccgtag gaactacggg gatagcctgt
      121 ggagaattag taagacatat gttagtatgc aaaattctgt gaagcaggaa acctgtgact
      181 ttagtcatgg gaggttcagg ctagtattac tcattattgt attcaaaagc taaagtggaa
      241 acctagtgaa tatatgaatt tagaagttaa tgagagagca ttagcagccg actcaatact
      301 tattaaaatt gaagatgaag aagaaacaat gaaagaagct gaaagagaga aaaagagagg
      361 tagaagaagg tagaatttaa agttaaaata gttacattgc taatatatga aaatgttaca
      421 aatttggaaa tagatggata tatatgttgt atagtataat gtagataata tatcaccaag
      481 taaaaaacaa caaataaatc taaattatga ggggtggaaa ataaagatat taaacttaca
      541 atatgtatat ttgcttttgt aattggaata atagtgttat tttgctgtat aggtctaggt
      601 caatttaata tggattgtat tataaaacaa aatggtgggt caatagctac cgaacaatac
      661 aacatatatt tagaacaatc tatttcacaa tatagaaatt ttggttctat actggtttta
      721 ctaggaggaa taggaatact gtttgataaa agtgtcagaa aatactaaaa aagtatattt
      781 ttatttagga tgtgatgaat gatatggcaa gagatgtatt tagtgtaaag atgacaccac
      841 tagaagcaca gaaaatggta gaaaaaaatt tggaagcaga tttagtttct gttgatattt
      901 ataacctaga aaataataag tctataatag ttacaatctt tgaaaaatat tatgcaagaa
      961 gcaatagtga tgcaggtttg gtagtgattt gtgaaaatac tacaggaaaa acacttgtta
     1021 aaattacctc aactggtagt gcaattggac tatttcagat tgattgggga acaggtaata
     1081 atttgattaa aagagtaaaa aaaatactta ttgattatat tatttaatta ttttatgtag
     1141 atattcttag gttggtatgg aatttgtact aacctattaa gtaatcaata aaactaaata
     1201 aacatagaaa gcacttacaa atatgtaggt gctttttatt gaaaaaatag aaaataaaat
     1261 aaaaagtaag atataggaaa aatatgtaag aattatatgt tataataatt gtagcaagaa
     1321 gatgtaatct acaatttata gagtggagtt catgtattaa aaaattatcc tcccaacgat
     1381 aagaagggag gtgaatatac atggataatt ttttatttaa tgtgttagct agtgtaacag
     1441 ctagttacat agtttatttg attagcaagt taatcaaaaa agtaaaaagc cactctaccg
     1501 caaagagtga cttaaagatt gatataaatt ttaaatatca tcgtaaaaaa taactttcag
     1561 ttatagaact tcactctacc gcaaatagat tgtagttctt cttgttttta ttataccaca
     1621 aattagaaaa aatattgcat ataatatttt ttatagtcaa taaaaatatg aaatttttta
     1681 tacacaatga tgatgaatct aactagatga ataaatttaa ttgtaaataa gaaagtactt
     1741 acttaaatgg taggtgcttt tgttttgcca aattatgcta taatattgag tgagatgagt
     1801 aatttgtggg ggaattttat aatgtggata ttagtaccaa taataacaat agtattactt
     1861 ataatagctg tttcttctat gcaatatatt ttagttatga tagctttttt gttgattata
     1921 tattctttta tagaaaagaa aatagttatg ggtcttgtgt cagttctttt tttcacttat
     1981 tcaatttatc tttgtgcaac ttgggaagat aaatccttga tagcagataa taaagttgag
     2041 actgttaggg cacaaagaga aactgtagaa agagaaaaag aaatggaaag aagaagaata
     2101 caagaagaag tagacaaaga aagatatatt gaaaaacatg gaatggaaat atcagaaaat
     2161 gatttaaaag ttaagctaga ggctttagta cctcaagaat ataaggggaa gaaatatgaa
     2221 ttaaaagtag gaaaatttaa aagatatagt atgtattttg atttaactgt acaaaatgaa
     2281 aaatttagta attctgaaga atgtaaaaaa tttgtaaaag aaattgctaa tgatcttaaa
     2341 aaaattaaaa taagcaaggc gtactttaag tttcattcaa aagatgacgg cggtatatat
     2401 aattctgttt atattgatta ttttagaaac atacaaaata atgtagataa tgttgaaaat
     2461 ttagaattca atgagtttga acttaaaacc gaagaagaag agaagcgaga acaagagaaa
     2521 atagaacaag aaaaaaacag ttataataac tacattcaaa acagagtggt tgacccacta
     2581 gatagaataa agaaactaaa agagttgcta gattcaggag caattacaca ggaagaatat
     2641 aataaaaaga aaaaagaatt attagaatag ataatatagt aagcacttac aagtatgtag
     2701 gtgcttttaa atttacaaag tattccattt taattttata gtttagattt tatgatataa
     2761 taaaaatata gaagttttgc agtgtgcgat atttgttaca aagtagggct taatacttga
     2821 aatctaagat gttgagggtg cgtgataagt gttatcaatt gcactattgc ccgctcactg
     2881 caattttaag agtattgtat atatgtaggt attggaaatg ctaagtttat tttggggttt
     2941 tagattaact atatggaatg taaatattac atgggtaaaa attttgatga tttttatgac
     3001 agttttagat taactatatg gaatgtaaat tgtatagaat taagaatttt tttaatacta
     3061 attatagttt tagattaact atatggaatg taaatattac atttaatttg cattgctttg
     3121 atgacttctt tgttttagat taactatatg gaatgtaaat gcgtacaagg ttgagaagct
     3181 ccgcaatctc aacgtcgtgt tttagattaa ctatatggaa tgtaaatatt tgaaaggaat
     3241 aaattttaaa tgaatgaaag gataggtttt agattaacta tatggaatgt aaatcagcca
     3301 aaaacttcga atttgaacta aaatgcgtgg gttttagatt aactatatgg aatgtaaatt
     3361 ctcatgacta ttgaataaat ataataaaca agcatacgtt ttagattaac tatatggaat
     3421 gtaaatttag aatcaaaagc acttaatcct agttctttca tagttttaga ttaactatat
     3481 ggaatgtaaa tagcttttta gcttcgtcta ctactttata agcaaagcgt tttagattaa
     3541 ctatatggaa tgtaaatgat gaacaataaa acaatcatct aaagacgaag aaagttttag
     3601 attaactata tggaatgtaa atgttcctgt tgtgtttttt actaatccca ttttatatgt
     3661 tttagattaa ctatatggaa tgtaaattgc tgtgatttca ctaataaaac aattaataat
     3721 tgtgttttag attaactatg tggattcaaa attaaataaa caaagaaagc acttacaaat
     3781 atgtaggtgc ttttattctg ctcaaaattg gtcggttggg taaaatcatt agaaaaaatt
     3841 agtaaaaacc tcttttctgt aactcgttac aatattatta ttaatgtaac gagttacaga
     3901 aaagaggtga ataaaatagc aactaaaagt agggcagagt atatgaaaaa ttgtcgaaaa
     3961 gataaaagag gttttagtgt acttttagac aaagaaaagt tagataaatt tgatgaagta
     4021 ttagaggaaa agaatctaac caagaaagaa tggctagaag aaaaaatcga cgaggaactg
     4081 gaacaaaagg aataaaaaat aagggtcact cccaccgacc aaagtttgag taacccctat
     4141 gatgtatact atcgtatatc aattataata tatgtcattc cttaaaaaaa tcaattatta
     4201 aggagtgtaa tattatgaaa aatgaattaa tgatgtttga aggaaaagag attgaagtat
     4261 ttgaatttga aggaagaatt ttattcaact caaaagatgt agcaaattgt ttagacataa
     4321 aaaatgttaa tgagaatata atacttatga atgaaaagca agttgtaaag ttaagaaatt
     4381 cggatatcag taatactgac atccgaaaac ttaataatgc tggagaaaat tttcttactg
     4441 aaagtggagt gtataaatta atctttaaat caagaaaaga agaagctgag agattccaag
     4501 actggataag cgatgaagtt ttaccaagca taagacaaac tggtgcatac ataactaata
     4561 atgtaatccc gaaaagttga gagaaaaagc aagtgagatt gaaaaattac agttgcttat
     4621 aacagtacat ctatgttaaa agaattgcta gatgatgcag gctttgacaa taaatcaaaa
     4681 ctattaacag ctaaaacatt atataagaaa gcagaaattg atttaccaat agagataaac
     4741 gaagaagaac attattttga tacaaaacaa atagcatcta aactgaaaat atattctaag
     4801 agtaataaac cagctcagat ggctgtttgt gagattatta aaaagattga tttagaagat
     4861 ggtgaagtta aaggtgtttg ggaaattaat ggttcttgga ctggtactgt aaataaatat
     4921 acaaagagtg taatagataa ggtgagaact tggatagagg aaaataatag acctaccaag
     4981 attgcaggtg agaagaagaa ttattatgta ttttacaaaa ttgagtaaat ttatcagttg
     5041 tattaaataa tttagtttag ttttgggggg attaatacaa tgtgtgagaa tttacttgat
     5101 aatatgtata ttgaaaagag aaaagaagaa tatagaatta aacttttgaa aataagagaa
     5161 acagatatag atatatataa taagttagaa agtatagtat ataaactttc tgagaaaaaa
     5221 ttagagaaaa ataataaata gacatataaa gcacttggat attctactgt ttcaagtgct
     5281 tgtttggtat aaaatggtat aatggagata gagaattata ttaaccaaaa aatggagaaa
     5341 atagagaaga tgatttagtt gacgctttat cagtaggagt acctgcaggt aagacagaat
     5401 ctctagtacg attagttgga gatggaataa gtgatactca aaaaagttta ataaataaaa
     5461 gagaatttag aaatataact caaattggtg gaaatggaaa tgagaaagca tttagtgaag
     5521 tagaaaactt agttaaatag attagaaggt agcaactaga gttggttgtt accttctttt
     5581 tttatacttt ctctctctaa gtattttatt tttcatatct tctaatacat ctaatgcagt
     5641 agtataaaat tgtatattat ttctataagg tatagctatt ggaagaatgc ccttgttaac
     5701 taaaaaaata agaagtacaa taaataaaag tgtcataatc attctaataa aataattagt
     5761 gatatctgat aaatcaaatg ttaagttaat tgttgtagaa aatacaacag ccataataga
     5821 tatatacaaa gcaaaaatgg ggttactatt tttttgtaac tgtcctttaa gcctagattg
     5881 ctctatttct atatcttgaa tactttttat ggaatccatt tcactataat acttataaac
     5941 ttttaaataa tattttttat acttgtttaa agcttcttca ttatctttaa ggtctttgtc
     6001 acttaactct gatttaactt ccccaaaatc cataaaatcc ctcctacaat gttatataat
     6061 atactttaat ttatagcata tttaagaact tatatcagca atttgtcgaa cgattttagc
     6121 taaaaataga gtataatgat aggcttatta tttataagat attatttttt atatagttat
     6181 atatttcttt ctaattagat aatataatgc tgttgttata atggctacta atattattgc
     6241 tattattgta atatctaatc ttcttgtaaa taagcctatt gctatatact caagacctgt
     6301 tacatagcga taaagtactt ctagtttaac agtttttttc ttatctatat ttccatatat
     6361 tgattctaat ttattaaaat attttttact acaaaaagca gttttaggtt taattaaata
     6421 tattattgta gttcctatta taactattat tccaataagt ataagattga tatttccaaa
     6481 atccatagca gatacctcct attaaatttg cttttcttaa tcaaagtata tcagtaacac
     6541 aagtacaaag agtatctaaa atattacaaa tattaacagg atagataaaa ctatagtaaa
     6601 aattgtaata ataaagcgaa cgaaaattat catactaaaa cataagacat gttataattg
     6661 tattagatag aagattaaca tacaccaaag cactccttat aataaagagt gcttattttt
     6721 ttgaaattca tcaatatata aactatcaag aaccttattc aacacacctt aaaatcgatt
     6781 taaatagttc tttttgataa cataatttat atgatataat aaaaaaatag aagtgtacca
     6841 ccaatacact tctatagcta taactaagca ttctcttgct gggggagtgc ttttttcatt
     6901 tctccaaaca acattattta cttcatcagt aattatcaaa tcaatctcat tatctttcaa
     6961 aatctctgtt gcagtacaaa ttagattatc taagtcaaaa cttcgagtta tctctagttg
     7021 tttgttattt acttctcttt ttagtatata agttttaaaa tacatttata tcaccccttg
     7081 tatttactct tttttctcta aaaatatatt gataagtaaa tatgcaacaa ataaaaaaat
     7141 ctcaatgaca catagtgtta tagctataac tagaagtgat tgatttttcc atgcactata
     7201 agctatgatg aaaagaaatg taaaagtaaa taatgtataa ttcataattt taactaagat
     7261 atgacttgtt ttcattgtta agtacaagtc tctttcatct gtactatcgt gtaattcttc
     7321 aacaatgcct tttcttgaaa aagcattaca aaaattaaag attgctatta caattaaaag
     7381 aaatgatgaa attaggaatc ttttatcttt taaaatgcaa taaataacta aactagcaca
     7441 acataacaca caaactataa tacccactat aaaacttcgt ttactcttta ctttcatgtt
     7501 ttttatcctc catttcttta ttttctttta aacaacatag ttcttcaatc gttgtaccaa
     7561 acacttgtgc catacgatag gcaagcataa gagaagggct atattgctct ttttcaatag
     7621 aaataattgt tctgtttgat acatggacta aatcagcgag ttgttgctgt gttagaccca
     7681 tatttgttcg aaattctcgt acttttgttt tcattccata acctctttct atatgaagct
     7741 aacttcatgt gaagttaact tcataatatc ctaaaatgag taaaatgtca atctcattag
     7801 ataagtatta taaaacctaa aagaataata tggtaaaaat tggatggaat tatttacctt
     7861 aattctcttg tttgtaaaac tttattgata tagaatttaa catatacata aatcggcaaa
     7921 ggggcgcgaa ttatgaaaat tagtaaatta ccagaagcgg aattaaaagt tatgagatat
     7981 atttgtgaag ctaacaaggt attaacttct agggaattag ttgctgcaat ggaagaaaaa
     8041 tatgagtgga atgaatcaac tacatttaca gttttgaaaa gattagagcg aagagagttt
     8101 ttaagtacag agaaaatagg caaacttaca cattataata tactagtaaa agagaaaaaa
     8161 tatctaaggt ttgaaacaaa ggaatttttg aagaacatac ataaaaattc aatttcaagt
     8221 ttaatgtcag cgttacatgg tgaagacgac gaagtggatg aagataaatt aagtgaactc
     8281 gaagaatgtt ttaagaattt gaaataagaa aatgacaaat tgatacataa taaataaaat
     8341 gaaggtatga aattataact ttttctacct tcattttgtt tattattctg aacatgttaa
     8401 gaaaatgaaa taagtttgta ttttagttat ataaatttta atagaatatg tacagtatat
     8461 agtagataga atgtataaaa atagaattta aataagtagc tattattgca gtgaaatgaa
     8521 tgtttctaag tatatttggg tggaagaatg gtggaagaaa attagtgaaa tgtaattctt
     8581 ccaccattct tccacctaga aaatagaaac tgtttaataa gaattaatat acattaattc
     8641 agctgaatgc aatcaaaata cttaaatgaa agtaatctga aaacaacata attcaaatca
     8701 atttattcaa ataaacctca atttatctta aatcttaaga aatatttaag aattaggata
     8761 atattttctt aagatttata ttttattata tagttataag ggaaagttac aaaaatgtaa
     8821 gccaaagtaa tataacaatt tagtcattgt tgagaaaggg agtgaaagat attgtataat
     8881 atagataagt attattatac aatagaggaa gtgaaaatat gtacaatata ttagtagtag
     8941 acgatgataa agaaattgtt gattcgatag aaatatatct taaatcagaa ggatttaaaa
     9001 tatataaagc atatgatgga atgaaagctt tggaaataat aacagagaat gacattcatc
     9061 taatactaat ggatataatg atgcctaaat tagatggaat caaagcaact gtaaaaatac
     9121 gagaagaaag aaatattcca ataattttaa tttcagcaaa aagtgaagat acagataaaa
     9181 taataggatt aaatattgga gctgatgatt atataacaaa gccatttaat ctattagagc
     9241 ttatagctag ggttaaatca aacttaagac gatatgtaac tttaggtaat tatgaagata
     9301 catgtaaaga aattctaaaa agtggagctt tggagttaaa tacactaaca aaagaagtta
     9361 aaattgatgg tgaaaacata aaaatgactc caattgagta taaaataatt gaacttcttt
     9421 tagaaaataa aggacgagtt ttctcaatag atgagatata cgaaaaagta tggaatgagg
     9481 aaagttttaa ttcagaaaat acagtagcag tacatatcag acgaataaga gaaaagattg
     9541 aaataaatcc aaaagaacca agatttttaa aggtggtgtg gggagttggt tataagattg
     9601 aaaaatttta gtggaaaaat tataaaagaa aagagtttaa tatttaattg cattttgatt
     9661 ttagtcattt ttacatttac acaaatgtta ggaattttaa tatgttttaa ttttttctct
     9721 gagagtttaa tttactctat ggggattatg cttttcttaa actttatttt atataaaata
     9781 ctgacaatgt agatgaggtg ggcaacttgg agaaatatag agtattaaag ttagtttcat
     9841 taatcataat atctatctca tttccattaa ctatattgtt ggtgacaata ggacttgctg
     9901 agcctaaata caatatacaa aaaacttcta caaagagtgg gatttttgat atatctgatg
     9961 atttttatga tagtaatata tttgacgaag gaacaatggc aagtctatta cccaagttta
    10021 agctatctgt aggtggtaaa ttaactagta aagaaaaagg taaattccaa caagaaggta
    10081 aaagtataga tttaagtagt agtgattctg agtatgataa aatcatgatt aatgaacaag
    10141 cttctgaaga atatttaagt tatctaaaaa atataaaagt gtatgttatt aatacataca
    10201 caggagtatt ttatacaaat acgtcatatg ctagtttata tgattttaaa caaaaaacta
    10261 agagctattg taatgtagag ataataaata agataggaaa gagctcatat attaaaacaa
    10321 taaatggaga aaaatttgaa ctgaataatc tgagtctgga actaaatgaa gtagatgaag
    10381 gttttgaggc atatgtatct tttccagaag agccaactat agaagatgga atagtataca
    10441 ctaattttca aatatttaaa caagctacag aaaaagtaag attatttttt gtagctagtt
    10501 taagtttagc aattatatgt ttattatcta taattttata tatcaaaata aaaggtgaag
    10561 ttttaaaaag aaataatgta tttttactaa tatacagtaa gatacctatg gaatttaatg
    10621 taatattagt atctatttca attgcaattt taactatata tgctcttgct gtatcttatc
    10681 atattgatgt aattgcatta gtttctttat ctttactgat agtatcaaat aatatatttt
    10741 ttataaatgt gcaattgagc tatttagaaa ataaaatgtg tatatttaag acaagtatta
    10801 tagtaagagt gattttatgg ttaataaaaa ctgtaaggga ggtcagtaac gctataaaga
    10861 aagtatcttt agcaaggaaa gttattgtta tagtgataat atctttagct ttaatcatgg
    10921 caattagcac tcgaagtata ggtatgggat tactgttttc tatatgtatt tttttaggat
    10981 ttacaatata tataactaaa agactttcat atcttagtta cgtaatagaa ggtacagaaa
    11041 gaataaaaaa gggagaatta gattataaga taaaaattac tgggaatgat aattttacgt
    11101 ctttagctga aaatataaat aatattggag aaggtcttga tagagctata gaagagcaag
    11161 taaaaagtga aagaatgaag tctgacctta taacaaatgt atctcatgat ttgaaaactc
    11221 cacttacttc tataataaat tatgtagatt taattaaaaa agaagaatca atacaaccag
    11281 agtatataaa tgattatata aatgtacttg agtcaaagtc aaaaagacta aaattattga
    11341 tagaagattt atttgaagcg agtagagtaa gtagtggcaa tatagaatta caaattagca
    11401 agattgattt agtgcaacta ttaagacaaa gtataggtga acttgaagaa aaattatcta
    11461 aaaataattt atatttaaaa ttaaatgttc caaatgataa ggtgtatata tgggcagatg
    11521 gaagaagaat gtatagagta tttgaaaatc ttttatctaa tatagcaaaa tattccttag
    11581 aagaaactag agtctatatt gatgtatatg actatggtga aaatgtaaag gtaactatga
    11641 aaaatatatc ttcttatgaa ttaaattttg acccaagtga gattatggaa agatttaaaa
    11701 gagctgatga atcaaggaat actgaaggaa gtggattagg gcttgctatt gcaagagatt
    11761 tagtagcttt acaaggtgga aaattttata tagaaataga tggagattta tttaaagcaa
    11821 atttagagtt tcaaaaatat gaagaagaaa taacaaatat ggaatgagat agtatttaag
    11881 tatatatatt tttttactgt cgaaagcttt tattataata tattagaata tttacagtag
    11941 agaatgaaga gtaaaaacag agtaacttta agtcactctg ttttttattt aaaatcaata
    12001 atataacaac ttaaattaaa attgtacaca tagttttaaa ataacttata caataaaaca
    12061 ttatccaaat atcacaagat aattccaaat aaatatatag atatcactcc tgtaataata
    12121 gaaataccaa tagatttaaa cttatatgca acaagaagta caatcataaa agatataatt
    12181 ttagggttag ctatagataa atatagacta tctccattaa aaaatacatc tttagcagtt
    12241 aaggaagtaa gtattgctac aggtataaat ttcatgattt ttttcaaaaa atcaggcatc
    12301 tctttttttg aaaaaattaa cataggaagc actcttggta gatatgtaac aatgtacatt
    12361 ccaattataa taaaaaatat ataattatta ttcataagat tcctcctttt tacagtaaga
    12421 ttcttctata aagaaaccaa ttaaagatgc taaaattgat gcaactatta ttactaaatt
    12481 gcttttgaat aatgcatata aaataacaga aataatgatt gatgatataa atactacaat
    12541 ataaatctta ttttttattt gagaaactat taaagctata aacatagaag tcaatatgaa
    12601 gccagaaata gaactgtcta tagatatact ttctcctaaa aatgctccaa taaaattagc
    12661 taaaactgat gaaattaagc agaagaaatt aagataaata gcatttctat cagaccaatt
    12721 tccagcagta aatttttcat aattaactgc aaaagtttca tctgttatag tatgacaaaa
    12781 tggcaatata aattttggac ttttattttt tatgtacatg ttcaaattag aactcattag
    12841 aaaatgtctt aagttaacta taaatgtagt caaaacaata gatgttacac ttgcaccagt
    12901 agaaatcatt gaagctgcaa tgaattgaga acttcctcca aatactaaag ttaccattag
    12961 tgctatttga aaaggtgaaa gaccagattt ttgtaatagt attcctccta ctatacctat
    13021 aggtatataa cctaagaata taggaattga agcaataaag ctttctttta attgttgagt
    13081 tctttccaca ataaatcact ccttttgtat taaatgtatt aaagtattcg taaaacagaa
    13141 aaatagatta attgtataat tgcaattata attaaaaata aatttggatt aatatataaa
    13201 atactataca acaaatagat aatcttaaac ggttattaaa ttttatctat ttgttattat
    13261 gatgtaataa tacatattaa tctctataag ttaattacta tctggtgtaa ttttatttta
    13321 acaacaaaaa aaaatacaca caattaaaat attgtgtgca atacaattat tttttctctt
    13381 ctaatagtct ttttaatacg ctcaaaccag ctttaagttc ttctgtactt tctgtagcac
    13441 atacagctat tcttattgca gaaattggtt tttcttttcc aacagcaaaa cgttcagaag
    13501 catagacctg tacaccttct ttaagtgctt gtatctcaaa tttttctgcc attattccat
    13561 caggtagaat caaccatcta aatatacatt cttcatttcc caaaagatta tatccagata
    13621 aatattgatt aataatcttg tttcttcttc ttgcagattt acggcgtgca ttaattaatt
    13681 tatcggcttc acctgatgta atcatgcgat aagcaatttc tgttaaaaaa taagattgag
    13741 atagattaat gttgtataat gcgcttgata atgcctctcg atactgttta ggtgtagaga
    13801 tatatgctag ccgtaaacta ggtgcaataa tttttgataa actcgtaata taaattgttt
    13861 gattgggcag ataggaagcc actggattta aatgtgtttc attaagtaaa ctatgaatag
    13921 catcctcaat aacaattaaa ttgtatttag atgcaatatt tgcaatcatt tttcgtccat
    13981 tttgtgacat tatatgtgta gttggatttt gataatctgg tattatgtat agacctttaa
    14041 tattttcatt tttacaagca tataatagtc cttcttcact aatctcatta tcttcttgtt
    14101 taattggaat tagttgaatc ccaagcattt tagctgctgt ctttattcca ggataagtta
    14161 atgggtctac acctattcta tctccatgtt gaaacaaacc agctaaaata gcaacaattg
    14221 cattttgtcc accacttgca ggaagtaagc tatctgatgt agtttcaagc ccagctttat
    14281 aaattaattt ggcaatagct tctttttgcc atttagcacc atctctttgt ccatattgga
    14341 atatggtttt aaaatctatt tccttaatta tgtgtttaaa caaagtattc atttcttcta
    14401 gtgtgaaatc tggattcatt gtgcccattt caataaatgt aattttatta ttactggaca
    14461 tcaagaatag atttgaacgt gtatcataag atacaaaagt tccacttcct gtaactccac
    14521 ttattagacc ttttttttca caaattttaa aagctctaga gatagtactc acattaacat
    14581 ctaagaaatc tgccaattca cgttggggtg gtaatttagt acctggtaat aaaaatccat
    14641 tgttgatatc ttgttctagt tgttctgcaa gcgccttata taatatttgc ccttttgaag
    14701 gtctctttgg tttccagttc ataggataat tttcaaaaga attaattggc ataagttttc
    14761 acctcacatt attaatttga ttttttcttt atctaaaaca ataaattcta aagatacaaa
    14821 taaaaactga taggaaataa ttctatcagt ttttgtcttt taattgattt caaatcttcc
    14881 tataattttt ataccttctt tatcataaag agggattgtt tttttaaata tattaaaatt
    14941 tctttttctt gtatataaaa cagcttcttc tggtgtcttt ggttgattat cacaatcgta
    15001 caaatctctt ttttttacgt agccgacttt tttacctcta cctattgttt gtataagttc
    15061 tggttcaatg gaatttccat ttgagtctat tatatgtgta ccataggttt ctccattttt
    15121 attataatta atcttaccaa tagtatattc tacatcttca ttttgtttaa aattggagtt
    15181 gatagaaaat attgacccta ttattataaa ggttaataaa aacttaagac ctaaattaat
    15241 tttcttttta tcttgattaa acatagaatc taacctcttt tttaaaataa tatttttttt
    15301 atttagaaac tgagatacga atgatgaata cttcaaagat ttttgatact ttattgtatc
    15361 taatattata tatgcatact ctttaatttc actcgtggta cacttgtcaa tcacaatttc
    15421 atcacaagat aattcacata attcatgaaa atattttttt aataagtata aaattggatt
    15481 gaaccaatat atgatacaaa ttatactaat tagaagctta aataagttat cttttctttt
    15541 ataatgaatt aattcatgtt taaagatgaa tcttaactct ttattattgt actttttttc
    15601 tggaattatt attttacagc gtgttaaacc tataatggca ggagaataaa tacctttaac
    15661 cttatatatc tgaagttttt tatttatact tagttctttt gcttgttcat ctaagatact
    15721 agtaatatct atttctaaaa tttctttttt aaaattttct atgtaattat aaaatttaaa
    15781 atttgttctt aaatagtaaa aagagattgc tataattcct aatatccaga tgtacataaa
    15841 tatatctaaa gtaatgccct ggtcatatgg tatataatta tcgatattat gcttatagat
    15901 attaatagta gtattattga tatttaatat atttaaattt attttagata taaacatcat
    15961 tctgactact attaaaagac atataaaata attaaactta aaagtatatt tgcttatctt
    16021 tttagtaaat aaaatgaaaa aaagaattag tggacttatg taaatattaa atttaataac
    16081 ttctataaat aattccataa aatacgtctc ctattttctt ttttttagcc attgttcaag
    16141 ttcttttatg tcatcatctg atatttcatt tccacaacct aatgatgata taaagctatg
    16201 aatagaattt ttatgtataa gctctaaaaa atcctttgtt tcaaatttta gatattcctc
    16261 atgtttaact ttaatagtgt ataaagtatt tctaccatct ttttcaaatt ctaaaaaacc
    16321 tttatcactt aatctagaaa gtactttacc agtagtacct tttgtccatc catgagaaat
    16381 ttccatataa ttagctactt ctctggctgg tattttatct atgtctttat cccatatgaa
    16441 attcataact aacaactcgg attttggtat ttttttcaat ataatcactc acctttaact
    16501 tgattatatt agacaaatgt ctaatagtca atataatata tcatcatgta taaataatct
    16561 ttatattatt ttatgcttga gaactaagta gtatagattt atagataaaa aagatattga
    16621 gagttttatg gaagagggga atatattttc tattagagat aagaatatga catatatttt
    16681 ttattgattt ttacaaaaat actatatagt gaataaatta atatcttttc taaattagaa
    16741 gaggagaatc ttattagata aagattatcc tctttattga aagtttaagg gatattagag
    16801 attattaatt tttctctctt tttttaacta aaagcaataa tacataaaat tattattgct
    16861 aatgatactc ttaatgtggt atatagtcat agtgtcacat gtttatcaat agttttttca
    16921 ttaattattg taacgaatag taggactcat aaaatactta gaaatatgtt tttagataga
    16981 ttttaaatat ataatctaac ttatatctat aaattaacac tattattctc caattccatt
    17041 tctagttttt ttataaattt attaaattct tctggttgcc tttttccaaa caatactctt
    17101 acaagagctg aattgatttt tccaaatata ttcctcttgc tctcactttc aataaaaata
    17161 agttttgtat tttctaagtc aatatgtact aattcatatc tagtaatagt actttctctt
    17221 ttattgcttg tttttatctc atatactcta tttttttcga aattagttat ttcaacctta
    17281 aatcttttat tatttttttg ctgtacaaat gttcctactg cttttttctc attaaaatta
    17341 ggaaaattta gtcttgcaga ttttgtaaat atattaaata tgtcttttgc agaatatttt
    17401 aataaaactt cagttttaaa tgtattcata tcgttttccc ttctgtatat aaatttaata
    17461 tttataagtt aatttttaag ttaaaatagt ataatatgcc atattaaatc atgttaaaac
    17521 tatttatata gctaaaatct tacctatata agtatgtata ctatcatata aaaataaaat
    17581 cttaaaatag aaagggttaa aaacacagtt tattataatt tttattgttg agtagatacg
    17641 tactattata tatgattgag caagtttttc aatcataaat ttataaagta ttttgcatta
    17701 aaatttaaac aaagaattaa attatttaag attatgaata actaatacat ttagtaaatt
    17761 actaaatata caaaatgtaa atacttatca aaatgtataa atacttatga catctagtta
    17821 cttacagggt ttaagtagaa aaaaatatca aagtaagtat ggcatgatag ttgcttatat
    17881 atttatcaag aaaggagtta ttaagcatgg agttgagaga taaacttgta aacatcataa
    17941 atacagaaaa taaaaaagat ccattaacag atgttcaaat agcaaagttt ttaagtacaa
    18001 ctagagagaa cataactaat ttgagaaaag aacttaatat aagtaattca aggcaaagaa
    18061 gatatcctta tttaaaatca gcaatttcgg caatattaca aaagaataag aatatttcta
    18121 tatcagaaat tacaagggaa ttgatgacag aaggctttaa tatatcgaga agagttgtgg
    18181 aggaactttt acctaaagaa agtttagaaa tggatgtagt agaggaagat gaagaagaat
    18241 cgaatgaccc atttgaaact ctgataggta ataaagggag tcttagaaat gctgtagagc
    18301 aggctaaatc tgctatattg tatccaccaa aagggttacc aacgttgatt attggggaaa
    18361 gtggagttgg taagagttta ttttctagac atatgtatga gtttgcaaag caaaaaaaga
    18421 tagtaaaaga gagctccaat tttgttgtat ttaactgtgc tgattatagt gacaatccac
    18481 aattattatt atctttgtta tttggatata aaaaaggtgc atttacaggt gctgaatatg
    18541 atacaccagg tcttgtagaa gaagctgatg aaggagtttt atttttggat gaaatacata
    18601 gattgcctcc aaaaggtcaa gaaatactat tttctatctt agatagggga aagtttagga
    18661 gattaggtga aactaatgct gaaagaaaag taagtattat gttgattggg gcaactactg
    18721 aaaatgtaga gactaattta ttattaacat tcagaagaag gataccaatg ctaataactt
    18781 tgccaccatt acatgataga ttactaaaag agaaaataga ccttatatac aatatctttc
    18841 aacaagagtg taatagaata aatgcaaaaa tatttgtaga taaaaatgtg attgaaatac
    18901 ttgcactaaa aaagtttagt ggaaatatag gacaattaca aaatatgatt caggttcttt
    18961 gtgcaagagc ttttatgaag tttataaatt ccaaagatga agatagtgaa tctatagtag
    19021 tagtagatat aaatgaagtt ttaaagctta aagattcgtt taaagatgct gcctttcaag
    19081 agattgaata tacagagata agaaaatatt tgaaaaatgc tatatttata ccatttaatt
    19141 tagaagaatc atcagtaaaa ggaagtcttt taagtgatga atatatatta ccagaggaca
    19201 tatacaaaac aattgaaaag aaatattatg acctaaaatc cctagacatt gaagatatag
    19261 atatagagaa tattttatgg acttttattt taaatagatt tgctgactta aagtttaatc
    19321 ttgatagtaa tgaagaaatt ttttcaatga gtgatttaaa tagttttgta agtgatagtt
    19381 tagttaaact ggtaaaagaa cttatgaatg atatagttga aaaaaatatg aatttagaag
    19441 taaataaaaa tatgttcaaa tatctagcaa tacacttaga agaagctata aaaagaatta
    19501 agctaaatca aaagataata aatgtaaatt tagaaaaaat aaagattgac ttttcaaaag
    19561 aatatgaaat tagtaaaagt tttgcaataa aaattgagga atcaattggt attaagattt
    19621 cagatgatga aattggattt ataacgctct acataaagtc tgctctaaaa aatgaagtga
    19681 aaaaagataa agtagggtta ataataattt ctcatggacg tatagctaca gagactgtaa
    19741 atgtagttaa agaactttta ggtgtaaagt ttcctgtggc tatagatatg cctttagatg
    19801 aaaaaccaat aaatatatac aataaggcag tagaattgtc aaaaataata gaccaaggga
    19861 aaggcatatt gtttttggtg gatattggtt cacttacaaa cataggtcaa atagtaaata
    19921 agagaaccaa tataagtact aaaactattg atagagtaga cctcctaatg gcactagaag
    19981 caactagaaa agtttctatg ggagaggaag aacttgatga aatatttttt tctttgctaa
    20041 aagataggat gggatataac tatgaattag aaaaacacat agataaatca aatgcaatta
    20101 taacattatg tcttactgga gaaggaactg ctaagtatat aagtaaaacg ttggaagaaa
    20161 agtatgataa cactaaatgt tatcaaatga gtgcattgga tgaaagttta ttttgtaaaa
    20221 ttgaaaatct aaaagagaca aacaatatat tagctattgt tgggacaata aaccctaaga
    20281 taccaggtat aaattttata ccctataata aagaactttt caaaaatttg gatatctatc
    20341 tatcaaaatc aaaacaacaa gatgacagac caattaaatc gtatgaaaga atgcttgatg
    20401 aggatttagt gatttttgaa ccagatatat attttaaaaa ggatttatta gaatatgtat
    20461 gttcaattct tataaataaa gaatatgtag aaaaagatta cttagattct gttttacata
    20521 gagaagaaat gcttccaaca tattctaaag gagctatagg tgtgcctcat ggagattctt
    20581 ctactgtaaa tagtacaagg tttgtttttg ttaaactaaa gaatcctatt gattggggtg
    20641 taggtaatgt aaatttcata tttatgccag tttttcaggc taatgataaa gagattgtta
    20701 aaaatgttct tgagatacta aaagatgcag aatttatgaa caatgccaat aagtgttttg
    20761 ataaagatgc ttttagaagg attatatttg ataaatttaa acatctgtag ccatagcaaa
    20821 aaaattgaga ggagttagag taatgaatgt agatttaata tcattgggtt tagaatctaa
    20881 tgattatgaa agtgttattg aagaattagg aagtataatg tgtaaaaaag aatatgtaaa
    20941 agaaacatac ataaatgctg tcttggaaag agaaaggaca ttaccaacag gtctagatat
    21001 tggagacatg tgtgttgcta ttccacatac agattcaaag catgtaaatg agtctaatgt
    21061 agctgtaggg atattgaaaa atcctgtaaa gtttaattca atgatagacc caaaagatag
    21121 acttgatgta gaacttgtat ttttattagc agtaaagaac ccagactcac aagtaaaact
    21181 gttaaaagat ttaatgtcag tttttcaaaa tataaagtta ttaaaaaata taaaaaacgc
    21241 atcaacaaaa gaagaagtag ctaaattatt ggattttata gaaatttaat gtaggagaat
    21301 tttataaata aaaaattaaa atttaaacaa tcaaagtaag tattattttt ttaataggtt
    21361 taatcttata taaaataaaa atttagagtg aaaaattagg aggaaattat tatgaaacaa
    21421 tttaatgtat tatcagtttg tggttcaggg acagttacat catctatggt agcaggtaaa
    21481 ttaaaagaag tactaggtaa taaggggatt tctattacta caacagaagc tagaccaaca
    21541 gaagcactaa atttagcaca atcaggaaga tttgacttta taacatttac gagtccactt
    21601 caaacaggcg attatggaat accaactata aatgcatttg cttgcctaac tggtataggg
    21661 gaagaggcat tctttgaaga agttttgact gttattgaag ggatagataa gtaagttttg
    21721 gagacgtgaa tttatagtat ttaaatcaat gatttagata ctataataag ctaatattaa
    21781 ctaaatattt gtggaaaaaa cattttatat gttgtcataa attaaaaaat tataaaaata
    21841 gtcacttaag tattaaatta agcttataaa tatttataag taggagggaa aaagatgtta
    21901 gaatttatga aatctataat cgatacattt ggttctgcaa ttatagttcc aattataata
    21961 ttcataatcg caaagatatt taaagtaact actaagaaat cgtttctttc tgctgtgtat
    22021 gcaggagttg ctttacaagg ttttacactg attttaaatt catttacacc agtaataaca
    22081 ccagttatca ataggatggt tgagagtaca ggagtaaacc taccagtttt tgatgttggt
    22141 tggcaagcaa catcattggt tgcattttca acaagtgcag gtatgatata tttaggtctt
    22201 ggtatattat tacaaacaat tttatttttg ataaaatgga cagatgtgtt tcaaccatca
    22261 gatttatgga ataactattc ttatatggta tggggagcaa tggttatagg agtaacagga
    22321 aattttcctt taggtatagc atgtatggtt ttattaaacc tatatagttt attaatatca
    22381 gagttagttg caaagagatg gtctagttac tatagatatc ctaattgtac aataatagct
    22441 atgcataatg ttgaggcttc tgtgtttgca gtatttgcag accctatata caataaattg
    22501 ggattaaata aaataaaatt aaatccaaaa gaattagaga agaaattagg gtttttaggt
    22561 gaaccaatta ctttaggtct ttttttaggt atgtttatag gtatattagg taatatgacg
    22621 agaataaata ctatggaagc ttggggagaa ataatgaaag taggtatatc tacaagtgca
    22681 gtgatggcaa ttttccctaa agtagcaagt atgtttgctc aagcatttgc acctataaca
    22741 gaagcagcta gaaagattat gcaaaaagct ggaaaccgtg agtggtacat agcagtaaat
    22801 gatgctgttg gatatggtga acctgcaact ttaatatcag gtcttatatt aattccaata
    22861 atgcttgtaa tagctatggt acttcctggt aataaggtat taccagttgt ggatttattg
    22921 gcaattccat atatggttca aggtttagtt gccatacata atggtaatat accaaaagta
    22981 ttagtttcag gtataatttg gtttggatta ggattatatg tttgtacatc tacagcacca
    23041 ttatttacag atatggctac aaatataggt gtagctatac ctgcaggagc aatgttaata
    23101 acaagtttta atatactagg aaaacctttg atgggattag ttttctttgc atttctaagt
    23161 gcaaatccaa tttatatagg tctttcagtt gtaatttact ttgttctatg ggcattgttt
    23221 agaaagaaca aaacaagtat tcttgattat ttagaaaaac aagcacttaa aaatgtagaa
    23281 gaagagcctg tagcagttta agtttataaa aatgaaataa aaataattaa aggagtttat
    23341 aattgatttt atataagtat cagataatac ctgagaaata tttaaatgaa atatagactt
    23401 ctttttattt gataatattt gtaattataa tgcattgtat ttttatagtt gagttttctg
    23461 tataacctgc tatttaaaac atactctttt atatttatac agtaatgtgg tttaatttta
    23521 taaaatgtaa tctctactgg taaaagactt tgtatataag gcatttgcct gaataaacca
    23581 tttatctttt gtatggcata gatattgcta tatagaagta tatagcatga aaggagatat
    23641 ttatatggga aataaaatga gagcatcagt attgtataat gtaggtgatg tcagatatga
    23701 aatggtaaat ataccagaaa taacagatac gcaagtgctt gtaaatgtaa aatatgttgg
    23761 gatatgtggt tcagatttac ctaggtctat ggtaagtggt ttgagtggaa atacaaaata
    23821 tccattgatt ttagggcatg aattttctgg tgaagttgtt aaaattggag aaaaagtaaa
    23881 gcatattaat gtaggagata gagtagctgt tgcaccatta gtaccttgtg gaaaatgtga
    23941 ttattgtaat gaaggtaatt ttggcttgtg tgatgattac aatataattg gaacaagagt
    24001 aaatggagcg tttgcagaat atgtaagagt tccagaagaa catattttaa aactaccaga
    24061 tacattggat tatgaaactg ctgccggaat tgaaccagca actatagctt atcatgggat
    24121 ttcaaagtct aatattagag taggagatag tgtagttgtg ttaggatgtg gtccaatagg
    24181 tcagtttgtt atacaatggg caaaggtgtt tggtgcatct aagattatag cagttgatat
    24241 ttttgatgaa aaattagaac tttctaaact tctaggagca aactatatac ttaactcaaa
    24301 agaagtaaat gtaatcaaag aaataaaaaa aataacaaat ggtggtgctg atgttgtaat
    24361 agaaactgct ggtagccgat ttacacaaga acaatctcta tttgtagcaa aaaagagagg
    24421 aaatatagtg tttgtaggta tatcacacac agaattacca cttagtgcag acgctactga
    24481 gtgtatatta cgtggagaac ttaccttgaa aggttcttgg aattcatata caagccctta
    24541 tcctggaaga gcatggactg caacattgga ttttatggaa aaaggtgaca ttatttttaa
    24601 acccatgatt tcagataaaa taggtcttaa tgaagtgggt gactttttaa gtaaaatgag
    24661 caagagagaa attaatttca ataaaatcct agtagaaata taaaaattta ataaaaaatt
    24721 ctaaaagcaa ttaaatttta taactatgac attaaataaa ataaaaataa ttttcttaaa
    24781 taaaatatag gaggaagaaa agtgttagaa aatttaaaag aagaagtatt aaaagcaaac
    24841 ttagaattac ctaagaaaaa gctaattact tatacttggg gaaatgtaag tgggatagat
    24901 agagaaaaag gattagtggt gataaagcca agtggtgtag agtatagtaa tatgactgta
    24961 gaagatatgg ttgtagttga tttagaggga aatatagttg atggcaaatt aagaccttct
    25021 tcagataccc cgactcatct agttttatat aaagagtttg aagaattggg gggaatagta
    25081 catacacatt caagttgggc aacaatttgg gctcaaatag gaaaatctat accatcttgt
    25141 ggtactactc atgcagatta tttttatgga agtataccat gtaccagaaa aatgactaga
    25201 gaagaaattt gcaatgaata cgaaaaggaa actggaaatg taatcattga agaatttatg
    25261 ggaagaaatc caattcattg tccaggaata attgtaaatg accacggacc ttttacatgg
    25321 ggaaaagatg caaatgaggc tgtacacaat gcagtagttt tagaagaagt cgcaaagatg
    25381 gcttattata cagagttaat gagtcctgat aatattatgg ataaggttct tatgaataag
    25441 catttttcaa gaaaacatgg aaaaaatgca tactatggtc aaaaatgatt atctggaggt
    25501 gaattatgct agactcttta aaaggtaaag ttgtggaaat agcaattaaa gcagagcatt
    25561 atggtttatg taaagaaaag actggtaatt ttagtattag agataaggat actggatata
    25621 tacttataac cccatcaggt gtaggaagag aagaattaaa agttgaacat atttgtgtat
    25681 tggatttgga tggaaatgta atagaagttg agaaaggtat taagccaagt agtgaggtat
    25741 tgatgcatat tgaaatatac aaaacaagag aaaatataaa tgccatatca catactcatt
    25801 ctttatatgc aacagcattt tcagtagcaa agaaaccaat tataccaatt gtatatgaat
    25861 cagttaatta tggcggttat gtagatattg cttcatacga aagaccagga actttaaaat
    25921 tagctaagag tgtttcaaaa ttactgatag atacagatgc atgcttatta gaaagacatg
    25981 ggttgacaac tgtaggtaat gatttagacg aagcattatt aaaatcaaga tatgtggaag
    26041 aggtagcaga aatatactat aggtctttag tattaaatca atttaaagaa cttgaagtag
    26101 tagatgttga tgagtttaaa tcttggaaat acccagaaga aataaagttt taatctaaat
    26161 aattttcatt gaagtggtta attaaaatat atgtattatt tatatcaatt actatgtttt
    26221 attatgttaa ttaccgtatt ttgcaaatat atttattaca ttttttcaaa aaaatataga
    26281 atccgaaagc catataaaat tgacttggga ttctatactt tttatttatg catttttctt
    26341 tatctgattt tctggagaat ttatatgttc aaaatatttt ttagtttcag atactattat
    26401 aggtgataat gcaagtaaag ctataaggtt aggtattgcc ataagcccat ttacaatatc
    26461 agcaattatc caaacaactt ctaactttaa gaaagcacct aataacacca tagccacaaa
    26521 tacagttcta tacccattca tgccttttac accaaacaga aattcaaaac atctttctcc
    26581 ataataactc catcccaaaa ttgtagtaaa tgcaaataat gttaaactaa ctgtaagtaa
    26641 tattggtcca aatgtaggaa ttgctccgtt aaaagctgct tgtgtcataa cagctccatt
    26701 taggtctgaa caccacactc ctgaaataac aagagagaat ccagtaagag tacagattat
    26761 aatagtatct ataaaagtac ctgtcataga tataagacct tgttccgctg gccattcagt
    26821 tttagcagca gctgcagcta ttggagcact acctagacca gactcatttg aaaatacacc
    26881 acgagcgata ccatttctaa ttgccagtga catagttgct cctaaaaaac caccagtagc
    26941 agcagtaggt gtaaatgcac ttttaattat taacataaaa gtttcaggga ttttattcca
    27001 aaaagatatt aaaatgattc cacagattac aacatatata actgccataa aaggtactat
    27061 tttagtagct acattagata tacttttaag tcctccaaat acaactaaag ctacaaatac
    27121 tgctaataca acccctgtaa ttctagggtc tatcccgaaa ctattattta ttgcatctgt
    27181 tattgaattt acttgagtaa aagtaccgat tcctaaaagt gcaactagta taccacttat
    27241 agcgaaaaat attgcaagag gtctccattt ttctcccata ccatttacta tgtaatacat
    27301 tggcccacca gacacttgac catttttatc tttagttctg tattttattg caagaacacc
    27361 ttctgaatac ttagtagcca ttccaaagaa tgctgctatc cacatccaaa aaagtgcacc
    27421 aggtccacca gctttgatag ctgtagcaac accaacaata ttaccagtac caactgtagc
    27481 agctagagca gtacataagg ctgcaaaact tgaaacatca ccactacctt tgttttcagc
    27541 agagaatatt aacttaagag ctcttggcag tttagttatt tgaacaactc caagcttaac
    27601 agtaagtagt ataccagtac caactaatag taccagtagg ggtggtcccc aaataaaagc
    27661 atcaactttg tttaaaatat caattagatt cataaaaaca ctccctcatt ttttttgctt
    27721 tacataatca atagaatttt taatgaagta attgacagga aataagtata atttattaat
    27781 aatttctagt gtaataaaaa aagctaaatc taaaaaagat tcagctctgg atgtacacta
    27841 attagcaacc aaaataaaag tattagtaaa tactgttttt ggtagataat ccctgtcctt
    27901 ttgcctgaga gattgagcat aaaagccttg ccccttcggc gcccataatg ggtctctcca
    27961 gagttccgta aattttacag tcctactttt aaaagtacct gagagtgtta ctccttcggt
    28021 gtgctatata gcaactcttc tataaaatct taaccggata ttgatttgtc atagcttatt
    28081 gtattaataa tattaatata agtttttatg ttttgtcaac taaaaaatta aaaaacaaag
    28141 aaaaaatata aaaatgtaag cctatttacg aattataaac ttagaaagat gagtaatata
    28201 cgtgaaaatg aattttgtaa tacacataca aatgaagtgt aaaataagtt ttaaataaaa
    28261 aaataataaa atcttaaata attaattaga tatgattaaa ttatggtaat attatagtta
    28321 cgatattaag aaaagttcta tttagttaga ttttaagcgt aatatgagat tatgtataga
    28381 gaaaggatgt atttttagat gggaaaaata ttagtgctag cagaaaaacc ttctgttgga
    28441 agagatatag caaaagtttt agggtcaaaa aatgaaaaaa atggttatat agaggggcca
    28501 aagtatgtga taacttgggc actaggtcat ttggttacac ttgctgaccc cgaaagttat
    28561 ggagaaagat ataaatcatg gagcttagaa gacctgccaa tacttcccaa gcaccttaag
    28621 actgttgtaa taaaaaagag tggaaagcag tttaatacag ttaaatcgca aatgaataga
    28681 aatgatatag atgaaatagt tatagcaaca gatgcaggtc gtgaaggaga acttgtagca
    28741 aggtggataa tagaaaaatc acaggtaaaa aaacctataa aacgtctttg gatttcttca
    28801 agtacagaca aagcaataaa agacggattt gcaaaattaa gaagtggaaa agaatatgaa
    28861 aatttgtatt actcagcaat agcacgagca gaagctgatt ggattattgg aataaatgca
    28921 accagagctt tgacaacaaa gtacaatgca cagctttctt gtggaagagt acaaactcct
    28981 actcttgcaa tgttgcttaa aagagaagaa gaaataagaa atttcaaacc taaagagtat
    29041 tatggattag aattaattgc tacaaaggga aattcagata taaaatttat ttggaatgat
    29101 aaaaacaata attcttcaac ttttagtaaa gaaaagatag aatccacatt aaaaaaagta
    29161 aaaggtgtag acataaaaat atctgaagta aacaagtcat ataagaaaaa atattcacct
    29221 gcactctatg atttaacaga attacaaaga gatgcaaata aaatgtttgg attttcagca
    29281 aaagaaactt tatctataat gcaaaaactg tatgaacatc ataaagtact tacttatcct
    29341 agaactgatt ctagatattt aacatcagat attgttggaa cattaaaaga tagaataaaa
    29401 gctgtaaata ttagtgatta ttcaaagatt tgtaatagat tattaaaaag caatattata
    29461 gctaataaat cgtttgttga caattcaaag gtaacagacc accatgcaat aataccaaca
    29521 gaacagaagg tattcatgag tgattttagt gataaagagc gaaaaatata taatcttgta
    29581 gtaaaaagat ttttagcagt actatctcct ccttttgaat atgagcagac aactataagt
    29641 gcaactgtag aaggagaaat atttaaggct aagggaaaca aagtaataaa tttaggttgg
    29701 aaagaaagtt ataaagatat tgaagatgaa gatgagtatg aaagtatacc aaatgtttta
    29761 gaaaaagatg tacttaaggt caagggatta aagataactt caggaaaaac aaatccacca
    29821 ccatacttaa atgagggaac attattgact gctatggaaa agaatggtct agggacagtt
    29881 gctacaagag cagatataat agaaaaatta ttcaattcat ttttaatgga aaagaaaaat
    29941 aaagatatat atataacatc aaaaggaaga caattattag atttagttcc agtagactta
    30001 aagacaccag aacttacagc ttcatgggaa aagaaattat tggatatttc aaagggaaaa
    30061 cttagtaaaa atacattcat aaatgacatg aaagattatt caaaagatat tgtactagaa
    30121 gtaaaaaata gtgataataa atttaaacat gataacttaa ctaaaaatag atgtccagaa
    30181 tgtggtaaat ttatgttaga ggtaaatggt aaaaaaggta agatgttgat ttgtgaagat
    30241 agagagtgta atactagaaa aactatatca caagtaacca attcaagatg tcctaactgc
    30301 cataaaaaat tagaacttcg tggagaaggt gaggggagac tcttcacttg tagttgcgga
    30361 tacagagaaa agttgtcttc tttcaacaag agaaagcaag aagaaaaaca gaaggcatca
    30421 aaaaaagatg ttaatcaata tttaaaaaat caaaataaaa atcaagagac atttaataat
    30481 ccatttgcag aagcattagc taagctaaaa aacaaataat tttaaagtta ttattataca
    30541 caattataac tttaactgta tattagttat atgtactgat ataatatagt gtatagttta
    30601 ggcatgaaag tagggctgtt aaatggattt aagtggcata tttaaatact attgtaaaga
    30661 gtgtgaaaat acatggaata attcgagtgt tgaattattt gagaatatag aaacgtatag
    30721 taaagattca caaaaaaaga gggaaaaaga attagataaa ttgctaaata caatatcagt
    30781 tcatttagag aggtatccaa gtgatgctgt attgagaaaa atgtgggtaa aaaagggcga
    30841 ggttttctta caaaagacat tggaaaaaga aaatattttt aagttagaaa aaatggatgt
    30901 agaggataga aaaaaatttt tagatataac aaaacagttt attagagatg ctagaaaatt
    30961 tgatgatgat ttacctatag gtgatattat gcaagctatg aggaatgtat ggatttcaaa
    31021 tgcattacaa ttattatttg gtaaagaagt atattattca aaagctaact ttgcatatag
    31081 tatgttatat ccatatactg ataattattt agacaataca aatatagata aaaatgataa
    31141 gattttattt aataactggt tagaaaaaag gctcctggga gaacacatta aatctaagga
    31201 ttatcatgaa agtaaagtat ctcaaatgat agattatatt gaaagtgtat accctagaga
    31261 aaagtttaca gaagtttatg aatcgttatt attaatattt aaaagtcaag taaatagttt
    31321 aaaacaacat ggtaaggaaa atcatttgtg taaagaagat ttattatcca tttctattga
    31381 aaaaggaggt tcatccgttt tagtagatgg atatttaata agtggattga tgacaaagga
    31441 agaaatagag ttttgtatag gatatggatt tttattacaa atatctgatg atttacaaga
    31501 tataaaagaa gatttaaaat acaaccataa aactattatt acagagatgt caaaagaggg
    31561 tactttagat aaagttgtaa ataaactaat aaattttact attgagttaa tagatagttt
    31621 taaaattaat aataaaaata aatctgtaat agctatgata aagaatgatt gcttaatgtt
    31681 aattttattt tctgtagttt ataatgctga atttttttct gtaggatata taaaagaagt
    31741 agagaaattt attccatata caatagatta ttcattagag attgaagaaa aaataaaaga
    31801 aaaatttaaa aatatagatg ttttaaataa tgaaaatgaa tataaagaaa tgattgatat
    31861 tatttgtgca gagtagaaaa aaagggagtg tcttagaata gactttttag tttatgaggc
    31921 actctttttg tataaaatca aatgtatttt catcatttta acaattaaaa agagcttatc
    31981 cctatttgag aaagcccttt ttaatttaaa taaaaatgtc aaggttaaac tatttaaatg
    32041 cagtaataat cccattatca tgtaagtttt ttatgattgt agctgcgata gggaatccaa
    32101 ataatccagc tattccaaat agttgagctc caacaaacat acacattaat gttattaaag
    32161 gatataggcc aatttggtgt cctactacct ttggttctaa tatttgtcta acaacggtta
    32221 taattatgta tagtattaaa agtcctattg ctaaattaat atttccatta atgagtgaga
    32281 taatcatcca aggtgtcaaa atacttcctg tacccaagac tggcaaaata tcaacaagtg
    32341 ctatgatgac agatatagta aatgcatttt caacctttag gatagtaagt ccaataagta
    32401 gttctatgaa tgtcactgat agtagtattg cataggcttt tagtagtttt aaaagagcat
    32461 taatactgct attttttata tttattatca taaattgact tttttctgga aattgtttta
    32521 agataaagtt tactattttt tgatagtcaa aagtaaagaa aaaagaagca attaaagtaa
    32581 taataagttt taacataaat gcaggtgttt tacttgcaat actagcaata gcattgagtg
    32641 catttgttga aatagaagct actaaagaca tcatagattg acttatatta tcccaaccaa
    32701 gtattaatgc taggttaaca ttaggtgtac tagcatctat ctttgaaaat aaagtattta
    32761 gcgttggttg tatacttgat ttatatattt caggaagtct aaaaaataca tcacttacac
    32821 ttgcaaatat cttcacacca aagctaacta ataaaaatat acacaaccca taaaaaatta
    32881 aaagtattac tatagaaata agtgtacgat ttaaatttgt attatttgta ataagtctta
    32941 taataggtct taagatggat gcaatgataa aactgattac aaaaggcatt aataatggca
    33001 ataagaattt taatacaata tatacaatac ttgttattaa aactacatat gtaaatttaa
    33061 ttataaaatt cttttgcttt tgaatatcca taatataaaa cctccaatgt atttgatatt
    33121 attctaaata tggtcttttt tacagaaaat atactactgt atattgatta taaactataa
    33181 agcttatgta aagtaaataa attatgtaaa atttaggtta attttgtata aagagatact
    33241 tttatatttt acaattaata accaaatact aaaaaatatt ttaaataaag aacttaaaat
    33301 tgtgataaaa ttaatttata gatattaaaa aaagtataat atatggtttt taagaggtgc
    33361 taagatgaaa aattttagag atttaggtgg gaacaaaact gaggatggca gaactgtaaa
    33421 gaagggatta ttttataggt ctgcaaaatt atcaaatcta agtgaaaatg atataaagat
    33481 tttaaaagag ttaaatatta aatatatatt tgattataga agtgatgaag aagctcgtaa
    33541 acatccatca acaataatat caaatataaa aaatataaga ataccagcaa tgagagagct
    33601 agaagaatca ggaggaagtt ttggttctat tgaagatatg attgatggat tgtttgaaaa
    33661 agatggtgca tttaatatgt taaataatag ttactataat ttgcctataa ataatccgtc
    33721 atataaaaaa ttagtagaac ttataagaga ctattctaat ttaccaatat taaatcattg
    33781 tacagctggt aaggatagaa ctggtgtggg gagtgctata attcttatga ttttaggggt
    33841 atcgagagag aatataatga aagattatct aaaaagtaat gattttgcag ataaagagat
    33901 agaaagattt atagaatata agcctaaatt taaggacatt ccaaaagaaa atttgaaata
    33961 tatatttggt gtaaatgaag agtatatgaa aactgcattt agaagaattg atgaagaata
    34021 cattagtgta gaagcatatt tatatggaga atttaattta aataaagaag aaataagaaa
    34081 attaagaaat caatatctag agtaaaaggt gagtttatga gtttaaatat aacagcaaga
    34141 cagataaata taataaaaat attgttaaat tcaaaagata caattagtgg tattgcctta
    34201 agtcaagaga taggatgttc ttcaaaaact atacaaaatg aaataaagga tattaataaa
    34261 caacttagaa atggtaaaat tttgtcaata agaggagttg gttataaact agaaggaagt
    34321 tttgatgagg taaatctaaa tagcaatctc tatgatgatg tagatagagt agaatatata
    34381 atcagaaaaa tattaacctt aagtaatgaa gaaaaaaata ctataaaact tgaagattta
    34441 gccgattcta tgtatgtaag tgtttcaaca gtaaaaaatg atttaaaaga agtaaaaaga
    34501 atgttggaaa agtattcaat atcagttaaa tctaagcata aacaaggtat atgtgttttg
    34561 gaaagtgaag ataagatatt aaattgtata gttgacttaa gcaataagag agataatcaa
    34621 ttgagtttaa atgatttttt aaatgatgat ataaaggaaa gaaaactatt aataaaaaaa
    34681 ttattattag acatattaaa tgaaaatgga ttagtattaa ctgatataga atttaagagt
    34741 gtgttaaata atatattagt tatgttaagc agacataagt ataatgaaaa agaatttata
    34801 gagaattata tagaaaatta taggagcaaa agaagctcaa ttttagaaaa tgaacaaaac
    34861 aaagaaatta taataaattc aataaaaaca ttttgtaaaa atttaaaatt agctacatca
    34921 atagatataa gtaatgataa ggtatttgaa gagtttttgt ataagcatat tagtagttta
    34981 tgtaaaaaaa taaagttagg tataaatcaa tcacctataa tggctcaaga tataaaaata
    35041 aaatatccat ttgcttttga actagctaat atagctaaaa agacaataga aaaagatttg
    35101 aagatagaaa ttaatgaaga tgaagttgca aacatagctc tacatatagg aggagcagtt
    35161 gaaagagcat cttataataa taaagataag gttttcaaaa ctataatagt ttgtacttca
    35221 ggcataggca catcaatgtt aataaaagct aaattagaga atatatttaa ggaaaaatta
    35281 gaaatactaa agattattcc ttcatactta gttgaatata taaaagttat agatgttgat
    35341 tttgtaatat ctactgttcc tattgaagta ggagatgtgc cagtaataaa tatatctcca
    35401 attttaagtg agaaagaaat tagattaatt gaaaaatata tagaaacagg aaatatatac
    35461 ctagatttag atataaaaag cctgtttgat agtgaattgt tttttactga tttggtgttt
    35521 aaaaggaaag aagaagttat agattttatg gcaagtaaac ttgtacaaaa gggctatata
    35581 gatgaggata tgaaaaaatc ttactttgag agagaaaaaa tagcaacaac agaaataggg
    35641 aatatggtaa ctataccaca tggagctatt ggaaaaattt ttgataataa aatagcaatt
    35701 ggtatattaa agaagcctat ttcttgggaa atatcagatg ttcgtttaat aataatgtta
    35761 gcccttgata aagataaaat attagattat gaagtaatat tttcaaaaat atataaaaga
    35821 gtagattcta tagcaaaagt tataagtata tgtgaaaata gtagttttga aaaatttgta
    35881 aatttattca attagatggg tagtattgta tatacacctg taaatttgga taatataaaa
    35941 ctaaataaga taaaaacgat aaatttctct tttaattaag agaaattttt tgactttcaa
    36001 ggatattaat ataaagttaa gatataaaca taaagcaaat aaataaaaaa gaggtggcaa
    36061 tatgatttat acagtgacat taaatccatc aatagattat atagttaagc tagatgagct
    36121 aaagacagga agtacaaatc gtgtaaaaga agaatacgtt tatccaggag gaaaaggtat
    36181 aaatgtatct cgcatattta aggaacttgg aaatgataat acatctttag gttttataag
    36241 tggttttact ggagaatata taataagaac attggaagaa aaagaattga agacagattt
    36301 tataaagata aaaagtggtt tttcaagaat aaatgtaaaa ataaaggcgt taaaggaaac
    36361 tgagattaat ggacaaggtc caaatataga tgatgaagac attgatactt tatataaaaa
    36421 acttgataag ctaaatcaag atgatatttt aatattggca ggaagtatac catctacttt
    36481 agatgaaaaa ctatacgaaa atataatggc tagattagaa aaaaagaata taaaagttgt
    36541 agtagatgca actaaaaatc ttcttcttaa tgttttaaaa tataaacctt ttctaattaa
    36601 gcctaataac gacgaattag aagaactatt tggtgttaaa ttaaattcaa ttgaagacat
    36661 ggtaaaatat gctagaaggt taaaggaaat gggagctata aatgtcttgg tatcaatggg
    36721 aaaagatgga gcattgttga ttacagagga agatgaagtg cttataagtg atgttccaaa
    36781 aggaaaagta aaaaattctg taggagcagg tgattcaatg gtagcaggat ttatatctgg
    36841 gtatttgaat actgggaaat atgattatgc tcttaaattg ggagcagctt caggtagtgc
    36901 aactgctttt tcatatgact tagccaaaag agaatacatt gataaattgg taaatgagat
    36961 atctgtaaag cagttttaaa atattaaaaa atatatagaa aggtaattaa tatttatgaa
    37021 aattatagat ttattagatg aaaagtcaat taagttaaat ttaaattcaa aaaccaaatc
    37081 agaagcaata gaagaattag tagatttggt cgcaaatagt ggaaatttaa atgataaaga
    37141 aaactacaaa aaagcaattt tggctcgtga agaaatgagt acaacaggaa ttggagaagg
    37201 tgtagctata cctcatgcta aaaattcttc agttactaaa gcttgtatag cagcagcagt
    37261 gtcaaaagaa ggtatagatt atgaatcgtt tgacggaagt ttatcaaatc tattttttat
    37321 gatagctgca ccagacggag ctaacaatac tcatcttgaa gtattatcaa gattatctac
    37381 aatacttatg gatgaagact ttagaaataa acttataaat tcaagctctg aaaaagaatt
    37441 taaggaaata atagataaaa aggaaagaga aaaattcagt gaagaatatc aagatgagaa
    37501 agttactgaa aaaaatataa tagatactaa agagaatgat gctaataagt atcctaaggt
    37561 tttagcagta acagcatgtc caactggaat agcacataca tttatggcag ctgaaagttt
    37621 aaataaaatg gcagaaaaca aaggtgtatc aataaaagta gaaactaatg gttcagcagg
    37681 tgttaaaaat aagcttacaa aagatgaaat agaaaatgca acatgtataa tagtggcggc
    37741 agataaaaat gttgagatgg ctagatttaa tggtaaaaaa gtcataaaaa ctaaggtggc
    37801 tgatggtata cacaaagcgg aagaacttat agacaaggct gtaaatggag atgctccaat
    37861 ttaccatgga ggagatggaa gtcacaacga atcaaatgaa gaaagtgaaa gtggatttag
    37921 aaaagtatac aaacacttaa tgaatggtgt atctaatatg ttaccatttg ttattggtgg
    37981 agggatactt atagcgatag cctttttact tgatgattat actattaacc cttcaaactt
    38041 tggttcaaat acacctatag cagcattttt taaaggaata ggagataaag cttttggatt
    38101 tatgttacct gtacttgctg gatatatagc atactctata tctgatagac cagcgtttgt
    38161 tgtaggattt gtaggaggtg ctctagcagg tgatggtggt tcaggttttt taggtgcact
    38221 acttgcaggt tttatagcag gttatttagt agaagggctt aagaaaatat ttagtgtact
    38281 accagcttca ttggaaggaa taaaaccagt attgttatac cctttacttg gaacactttt
    38341 gatgggaatt ataatgacat ttttagtaat acctccagtt acagcaatta ataatgcaat
    38401 ggttggattt ttaaatggtt taggtggaac ttcaaaaata gttttaggat tagtattagg
    38461 tggaatgatg gctgtggata tgggtggacc tgtaaataaa gcagcatatg tatttggagt
    38521 tgcatcactt gaatcagggc agtttgaaat aatggcagca gtaatggctg gtggtatggt
    38581 tccgccactt gctatagctc ttgcaactac attttttaag aatagattta ctaaagaaga
    38641 aagagattct ggtaaagtta attatgtaat gggattatca tttgttactg aaggagctat
    38701 accttttgca gctggagacc cacttcatgt tataccagct tgtgttggag gttcagcagt
    38761 ggcaggagca cttagtatgt tgttcaacgc agctcttcgt gcacctcatg gaggagtatt
    38821 tgttatacca gtggttaccc atccatttgc atatatatta gctatagctg taggtgcttt
    38881 ggttggaatg atgcttttag cattacttaa aaaaccatta aatcaagaag tatagcaatt
    38941 aaaggatatt caagaactta aaatatgatg ttttataaaa attaatatat tgctgaatta
    39001 ttttaaaata aggattttat gaggctgtta tataacgatt tgtaattgtt atcttgacag
    39061 tcttttattt ttatataagt aaaataagtg tgttttgctt tatttgtatt taaattgttt
    39121 ttaagttaga atataaagaa aattatatat tattttaata ttcactcgaa ctagaaaata
    39181 atatttgttg tatttttttg tatataaaat atattgtaat attaaaaaaa taatagtaaa
    39241 ctgattgcat aaaaatgatt tttatataaa atttaagcag aagaataaat ttctaacgaa
    39301 attggatatt tcttctgtaa atacatattc aaaaaaagaa ttataagagt ttagtcagca
    39361 gtcgtgtaag taataaggac tttataaata tatagaaata taatgatatt aatataacca
    39421 agcgattttt aatttagctt tttaataagc ttatttttta tactatttat aataaataaa
    39481 ctccatgatg ggaaaactat tactatttaa tatgtaaagg agtattttaa atgaatgaat
    39541 catattggtt tttaaactca agtccaaaag aatataacaa attaggtgaa aatataaaaa
    39601 cagattgtct tatagtaggt ggtggaataa cgggattgac aactgcatat ttattagcaa
    39661 aagaaggtaa aaaagtagtg cttgttgagg ctgataaaat aggatatgga acttctggaa
    39721 ggaatactgg taaggtaact tgtcagcatg atatatttta ctctaagata gagaaaaaat
    39781 atggattaga taaagcaaaa tcatattata atgcaaataa tgaagcttta aatttagttg
    39841 aacaaataat agaagaaaac aatataaaat gtgattttaa aagggaaact tcttttgtat
    39901 ttacagaaaa agaggatact ataaaggata ttaaagatga atatcgtaca tgtaaaaaaa
    39961 taggaataaa ttgtgagtat catgaaacta tagaaaatat tccattagat ataaaggggg
    40021 ctattagttt tactaatcaa ggtcaattta acccaaagaa gtatattgat ggattggcaa
    40081 aagcagcagt aaatttaggg ctaaaaatat atgaaaatac accagtagta gaccttgaaa
    40141 aaggaaaaat atgtagggtt aaaacaagag aggataatat aatagaagct gagaatgtta
    40201 taatttcatc tcatagtcca tggtatgatg gattgaattt ttattttgca aaagaatatg
    40261 cagagcgtgc ttatttaatg gttgcagttt tggaaaataa attagcagat ggtatgttta
    40321 taagtataga tgacccatca ataactttta gacaatataa tgatggaagt gaaaatttac
    40381 tgatttttgg aggaggagac cataaagttg gtcagggagg aactgagaaa gaaatatttg
    40441 atgatttaga gcattatggt aaagaagtct ttaaggtaaa agattttaag gggaaatggt
    40501 ctgctcaaga taatatgagt tttgacaatg ttccttatat tggttatatc aacaaaagag
    40561 aagacaatat ttatgtagct acagggttct ctaaatgggg aattactaat ggaactgctg
    40621 ctggaataat aataaaagat ttaataataa ataataattc tgattataaa gatactttta
    40681 atccatccag actaggtagc tacttttcaa aagattttat aaaggaaaat gcaaacgtag
    40741 caataaatta tgtaagtgga aaattaaaaa taggtagtgg agatatgcct aaaaataatg
    40801 gagaaggaaa gattgttaat attgatggaa aaagatatgg tgtatataag gatgataatg
    40861 gagattttta tattgtagac actacatgta ctcatttagg atgtgaactt aattttaaca
    40921 gtgaagaaaa aacatgggac tgtccatgtc atggttctag atttgactat aagggaaata
    40981 tacttgaagg accagctctt aagccattaa aactttatgg acatggtgat aatgatgtta
    41041 atcctaagtt attataaaat tatttttagg aaggtaaagt gtatatgaat aaacttttaa
    41101 agccaataac tatactattg tatatagttt atattttatc tgccgtattt tttgtagcaa
    41161 acaaagaata tggaagtcta ggtctagtag caattagttt agttggtact ttcattttga
    41221 gttttataaa taagcaaact gaaagattat tgagtaaaga attatatata atgcttgctt
    41281 tatttataat gttttcatca ttgttaggta cttgttttaa tttttatgat ataaattatt
    41341 atgatgattt tttgcattta tggtcaggta taatatcttg tattgtggct ttttctataa
    41401 ttaaatactt ttatacacaa agagagataa gtaaaatgag taaagtgttt ttagttatat
    41461 ttttatttat gtttagtatg ggagtagcga gtttatggga aataggtgaa tttttaatgg
    41521 atacttttgt tgggactact acacaggccg gagggttaga agatactatg attgatatgg
    41581 tagatgcttt aataggcaca attataacta ttccttttat agtaaaaaaa tctaatatat
    41641 agttttaaat tttttatatt aattataatg gatttaatta atcatgttga gtttcaaggt
    41701 ctatatgatt aattaaatcc atttttgtta tttataatta ttattgaata tatttttaca
    41761 tataagatat aaggtgatag atagaaattg ttggattatg taaataatta atatataata
    41821 ccattatggg caataaatac aaatcaaatg ataatatagt ctatttatgt aaatgttata
    41881 ttgtatccta agtataatag taagtttttt gatagtggtg tagaaagtaa aaatctacta
    41941 gcctaaattg atgtatggat tagtttagga acagtaattg catatcttaa gtttgatgtc
    42001 atgttgggct actagaaata ggtcatcttt ttcacttgaa tatcttttct ttaaacatgg
    42061 ggagtatcat atcaaaaaca tatgaaaatt aagtgattta tgagaacagt aatattttat
    42121 atgatagtat agaatagtaa taaagtatta ggaggaacat tgagtgttaa aaaagtggtt
    42181 tggtattgtg aaaaaaagac aaaaaagtga gtcagtaaaa gaagaaggtg aagtaatatt
    42241 aaaaaacgaa aaaatattat ctgaagaaaa gttgatagat gaagaaggag ttgtagttaa
    42301 tattgataat caaatattaa ctaaagtagt aaatgatgac aatgaaatag aagaaaaaat
    42361 aatagaagaa gatttgttaa ttagtgaaaa taccataaaa ttagatgata aagaagcaat
    42421 tattaatgat aaaaacatag aattatgtaa aaaagaagtt caagttgaaa gtgaaaaaat
    42481 aggtttaaat aagtttgaag gactggacca aaatgaaaat tataatctag aaaaaaatgt
    42541 tattgaagaa aaaaaagtaa gtgaatgttt gacagaagaa gatttagagt acataaaaga
    42601 aattaaaata aaaagaggaa aaagtataaa agctataaac ttgtatacta aagaagagtg
    42661 ggtttttgac actcatatac agtgtagtaa aaaactcaaa gttccattag ggtacataag
    42721 agaaaattta aaatatggat atatggatta ctttggagat gcaataaatt atttaagtga
    42781 agtattaaat atagatgaat actgcaaaag tgaatggagc tatctcgata atagcaaatc
    42841 tccatctgag atatttaata ttctaaacaa taaaatattt agtataaggc tttctaatga
    42901 aaaaagaaat gaaattttga caaatgataa aattgaagca ttaaaaatga attatagatt
    42961 tgaatgtatt gatgaagaat atgatgaata ttttaaaaaa tataagtcta taatcaaaag
    43021 aggtggaaag aaaaaagttg aattagtaaa taaaaaaggt gacattttag aaatatttaa
    43081 gtctttagaa gaatgtgcca tttatttgca aaaggaaaag aatgaagtta tacaaatgtt
    43141 aaaatatgga gatacaaaag taggaagaaa ctttataagg tatagtttga gaagtattta
    43201 atttcatttt aaattcataa gagtttcatt tctgattcac acatttaata ttattttaat
    43261 gtaaaataat aaaggtgaag tattgcacaa ttaaaattaa ggagggtatt aatgtctgaa
    43321 gaaaaaaatc caaaagaaaa tacattagat gaatctaaaa attcagataa tgtaaattct
    43381 aaaaaagatg atgtgtcaga tgaaaaaaat actgataaca aagttaaaaa aagggaaata
    43441 aagctaaaca acaaaacact taaagctatt gtagcaattg ttgcagtagg agctatatgt
    43501 ttaggtggag gctatgtttt tggcaaagaa gctggaagaa aattgcctgc tacttcaaaa
    43561 cactataata gcagtgaggt agtagctact attggggata aaaaaataac aggtgaaatg
    43621 ttaagaaaga gaatggagcc attattttat ttaaatgcaa aaactactat gactgatgac
    43681 gaaatacgtt catatgaatc aaatatgatt gaaactatga ttacatctga tatattatcc
    43741 tctgaagcag caaaagagaa aataagtata actaatgacc aactagatgc tcagtataat
    43801 aatttaatga gtagtataga atcagcaatg ggaatgacta aagaagagtt tttaaaacag
    43861 tttgatttga ctgaaaaata tataaaagat gatatgaaaa aagagctagt agcatcaaaa
    43921 tatttaaatg aaaaatcaaa agttactgat aaagaagcag agaactatta caataaaaac
    43981 aagagcaatt atttacaagt tagagcttca catattttaa taaaaactgt tgatgataaa
    44041 ggtaagcaag ttagtagtag caaaaaagct gaacttaaga aagaagctga agaaatactt
    44101 aaaaaagccc aagctgggga agattttgct actctagcta aaaaatactc tgaagatagt
    44161 agtgcagaat caggtggaga tttaggtttc tttggtaaag gtcagatggt ggaatctttt
    44221 gaaaaagcag cctttgcatt gaagaaggga gaggtatcta acaaacttgt agaaagtgat
    44281 tatggatatc atataattaa gaaaactgat gaaaaatatc agccatttga agaggtaaaa
    44341 tcagatttag taagcagttt aacatcagaa aaacaaaacc tacttataca aaatctaaaa
    44401 gaaaaatata atgttaaaat tacagataaa tatcaaatga aagctaaaga atagataaag
    44461 tcaatttatt aaaaaaaaga aaaattaact gtatggataa aagctatttt tactctcaat
    44521 atagagagta taaaatagct tttattattt tgcaataaaa tctatttata tatatgaagt
    44581 gataaagaaa taacatgcaa aaaggtatta aaaagaaata tttttaattt gaattttttc
    44641 aataaaaatt tacaaaaatg aaaaaataaa caaaaaagaa
//
LOCUS       DAMJWC010000031        42108 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMJWC010000031 DAMJWC010000000
VERSION     DAMJWC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.031"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            48..716
                     /locus_tag="PC503_001908"
     CDS             48..716
                     /locus_tag="PC503_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF2527880.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(807..2258)
                     /locus_tag="PC503_001909"
     CDS             complement(807..2258)
                     /locus_tag="PC503_001909"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF2527881.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALILLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2274..2714)
                     /locus_tag="PC503_001910"
     CDS             complement(2274..2714)
                     /locus_tag="PC503_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2527882.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDINNKDKLFTSLEESKNIIEQLF"
     gene            complement(2962..3390)
                     /gene="ytfJ"
                     /locus_tag="PC503_001911"
     CDS             complement(2962..3390)
                     /gene="ytfJ"
                     /locus_tag="PC503_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF2527883.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3344..3973)
                     /locus_tag="PC503_001912"
     CDS             complement(3344..3973)
                     /locus_tag="PC503_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF2527884.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            complement(4135..4674)
                     /gene="scpB"
                     /locus_tag="PC503_001913"
     CDS             complement(4135..4674)
                     /gene="scpB"
                     /locus_tag="PC503_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF2527885.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4676..5395)
                     /locus_tag="PC503_001914"
     CDS             complement(4676..5395)
                     /locus_tag="PC503_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF2527886.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5425..6021)
                     /locus_tag="PC503_001915"
     CDS             complement(5425..6021)
                     /locus_tag="PC503_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF2527887.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            6319..7155
                     /locus_tag="PC503_001916"
     CDS             6319..7155
                     /locus_tag="PC503_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2527888.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7176..7598
                     /locus_tag="PC503_001917"
     CDS             7176..7598
                     /locus_tag="PC503_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF2527889.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7809..8972)
                     /locus_tag="PC503_001918"
     CDS             complement(7809..8972)
                     /locus_tag="PC503_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2527890.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(9026..9226)
                     /locus_tag="PC503_001919"
     CDS             complement(9026..9226)
                     /locus_tag="PC503_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF2527891.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9432..11108)
                     /locus_tag="PC503_001920"
     CDS             complement(9432..11108)
                     /locus_tag="PC503_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF2527892.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11325..12062
                     /locus_tag="PC503_001921"
     CDS             11325..12062
                     /locus_tag="PC503_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2527893.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12179..12637)
                     /locus_tag="PC503_001922"
     CDS             complement(12179..12637)
                     /locus_tag="PC503_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2527894.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12919..13206)
                     /locus_tag="PC503_001923"
     CDS             complement(12919..13206)
                     /locus_tag="PC503_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF2527895.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13284..13709)
                     /gene="ruvX"
                     /locus_tag="PC503_001924"
     CDS             complement(13284..13709)
                     /gene="ruvX"
                     /locus_tag="PC503_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF2527896.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13915..16086)
                     /locus_tag="PC503_001925"
     CDS             complement(13915..16086)
                     /locus_tag="PC503_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527897.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDIMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(16096..16353)
                     /locus_tag="PC503_001926"
     CDS             complement(16096..16353)
                     /locus_tag="PC503_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF2527898.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16378..19017)
                     /gene="alaS"
                     /locus_tag="PC503_001927"
     CDS             complement(16378..19017)
                     /gene="alaS"
                     /locus_tag="PC503_001927"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF2527899.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19085..19323)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19466..20545)
                     /gene="mnmA"
                     /locus_tag="PC503_001928"
     CDS             complement(19466..20545)
                     /gene="mnmA"
                     /locus_tag="PC503_001928"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF2527900.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20834..21274)
                     /gene="nifU"
                     /locus_tag="PC503_001929"
     CDS             complement(20834..21274)
                     /gene="nifU"
                     /locus_tag="PC503_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF2527901.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21328..22521)
                     /gene="nifS"
                     /locus_tag="PC503_001930"
     CDS             complement(21328..22521)
                     /gene="nifS"
                     /locus_tag="PC503_001930"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF2527902.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22539..22985)
                     /locus_tag="PC503_001931"
     CDS             complement(22539..22985)
                     /locus_tag="PC503_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2527903.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23094..23864)
                     /locus_tag="PC503_001932"
     CDS             complement(23094..23864)
                     /locus_tag="PC503_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527904.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23895..25160)
                     /locus_tag="PC503_001933"
     CDS             complement(23895..25160)
                     /locus_tag="PC503_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF2527905.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25267..26052)
                     /gene="codY"
                     /locus_tag="PC503_001934"
     CDS             complement(25267..26052)
                     /gene="codY"
                     /locus_tag="PC503_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF2527906.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26217..28304)
                     /gene="topA"
                     /locus_tag="PC503_001935"
     CDS             complement(26217..28304)
                     /gene="topA"
                     /locus_tag="PC503_001935"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF2527907.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNIGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28337..29437)
                     /gene="dprA"
                     /locus_tag="PC503_001936"
     CDS             complement(28337..29437)
                     /gene="dprA"
                     /locus_tag="PC503_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF2527908.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29456..31057)
                     /locus_tag="PC503_001937"
     CDS             complement(29456..31057)
                     /locus_tag="PC503_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF2527909.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFSKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31088..31432)
                     /locus_tag="PC503_001938"
     CDS             complement(31088..31432)
                     /locus_tag="PC503_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF2527910.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            31616..32779
                     /locus_tag="PC503_001939"
     CDS             31616..32779
                     /locus_tag="PC503_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2527911.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSMHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            32772..33419
                     /locus_tag="PC503_001940"
     CDS             32772..33419
                     /locus_tag="PC503_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527912.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTIKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            33548..34483
                     /locus_tag="PC503_001941"
     CDS             33548..34483
                     /locus_tag="PC503_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527913.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGN
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            34497..35594
                     /locus_tag="PC503_001942"
     CDS             34497..35594
                     /locus_tag="PC503_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527914.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            35597..36661
                     /locus_tag="PC503_001943"
     CDS             35597..36661
                     /locus_tag="PC503_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527915.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            36905..37402
                     /locus_tag="PC503_001944"
     CDS             36905..37402
                     /locus_tag="PC503_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2527916.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(37578..37826)
                     /locus_tag="PC503_001945"
     CDS             complement(37578..37826)
                     /locus_tag="PC503_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527917.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(37892..38908)
                     /locus_tag="PC503_001946"
     CDS             complement(37892..38908)
                     /locus_tag="PC503_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2527918.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCVNSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(38966..39733)
                     /locus_tag="PC503_001947"
     CDS             complement(38966..39733)
                     /locus_tag="PC503_001947"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF2527919.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39801..41990)
                     /locus_tag="PC503_001948"
     CDS             complement(39801..41990)
                     /locus_tag="PC503_001948"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF2527920.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYGISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKKFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEGDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13496 a         7267 c         4451 g        16894 t
ORIGIN      
        1 atatttatat agatacatat taaatttatt ataggagaga atgttatatg tttaaaattt
       61 ttcttttttc tagtgaacaa tttgtaagtc tctttatatt tggattattt ttatactatt
      121 gtccaaaact aaccaaaaat attttacctt atagctatac agttgagaag ataatttgta
      181 cattacttgt aataattatg gctctagagc aattattact tatttcttca ggtaattata
      241 gtactctaaa ctctttacca attggaatca attatatttg tatatatctg tgtatagcca
      301 tactaatttt taagcagtat catcttttta atatattttt ttcttggagt ttagtttgtt
      361 cagttggaga actcattttt tctaaaaact tgggctatga atttcctagc ttaatatatt
      421 ttatctttat cttctctaag tgcttgataa tttatgcaga tatatatatg gttgatgtta
      481 gaaaatttag agttaacaga tatgcactta gagataactt agctatatgt tttatttatt
      541 tttcattcat atttttacta aacacattta ccaactctag gtactattat ggttttttaa
      601 gtcatagcac aactgctatt tttacgttta tttttgttac tagtattatg tacatacctg
      661 ctcttttatt taatagagat acttttatac ttgaaaaaaa gaaaaagagt aaataattta
      721 tttaaataaa aaataaagcc acatagataa tcttaaatta caaaaatatc cacgtggctt
      781 tataaattat attttataat tgttttttag atttctgcca aatagtacaa tgttctaaca
      841 ggttctcctg tagccccctt tgctttgtat ccaattgatt ttgatgatgt acttgtcccc
      901 gctatatcca tatgtatcca aggagtattc ccaacaaatt caccaataaa agctcctgct
      961 gttatacatc cagcattttt accaccagtg tttttaaggt ctgcttcttc tccttttatc
     1021 atatctttaa attcatcata aattggcatc ttccataccc tttcccctga taaagtggca
     1081 gctttttcta attcacaata aaaatcatca ttatttgtta ctataggagt tgcgacatta
     1141 cctaacaata ttaaagcagc accagttaat gtagctacat caaccacctt tgttactttt
     1201 tcattgttta taatgtagta tattgcatca gctaatgtaa gtctaccttc tgcatccgta
     1261 tttaaaactt caatagtttt ctttgccata gaactaatta tatctccagg tttgtatgaa
     1321 cctcctgata aagcattctc acatgctgcc actactgcta taacattttt ctttaattta
     1381 ctttgagata tagcacacat agcacctata acactcgcag caccagccat atctgtcttc
     1441 atatctagca tagaagcatt tgattttaaa gaatatccac cagtatcata agtcaatcct
     1501 ttacctacta gacctaatat atctgtactt tctttatctc caaagtatct cattactatg
     1561 aatcttggtt tattaattga acctcttgaa acagcgaaaa aagcatccat tcccaatgcc
     1621 tttatttttt cttcttcata aacatcaaca ttaaacccaa actctgcacc aagtttaact
     1681 gtttctactg ctaatgtttt tggatatatt acgtttgatg gttcattaac tagatttcta
     1741 gctattatag ttgaattagc taatatttta gccttttcta tttgacactc aacttctttt
     1801 tcagtaaata tagttatagt atcaacttct tttctttcaa aatccttact ttttgtctta
     1861 tatttatcaa acttataatt tccaagtaat atcccttcta caaaacaacc tatttcatca
     1921 ctatttaaat taagattcag tacattaaca tcactactct tatatgcttc atttttcaat
     1981 atatttttta attttttaca caaattccca cctatgattc taattttttc tctattcaat
     2041 aactctctct taccaaaacc aacaagacaa acatttacca aattgttatt ttcaaccaat
     2101 gttacagtat ctatactatt ttctttagaa ttaaaatttc tgcttatcat atttatttta
     2161 tcaaatgtcg tagaaacatc ttctccctca aatagagcta ctactgttat agcattttct
     2221 aaacttttta atatttcttt agaatacttt atattcataa taaattctcc ttttcaaaat
     2281 aattgttcta ttatattttt agactcttcc aaagaagtaa ataatttatc tttattattt
     2341 atatctaggc aatccatttt atcacttatt atagatacaa actttagtat ttcattatcc
     2401 aatatctttt ctccattttt agttattcca taaaaagtat ttcgtctatc tctactatct
     2461 tcttccctat atacatactc ttgctcaacc aatttattaa gtagtataca cagactagaa
     2521 gtagatacat gcaaatctct acttagattt ttaagctcta ttttatcatg ttttcttatt
     2581 tttactaagg caaagaactg tctttctgta agaaccttat cttttttata tctttcgtta
     2641 ttaataatct ttattaaatt atgaaaatta ttcatacttt ctaacaacaa aatagataat
     2701 tctttatcgc tcataacatt cacctcaaaa ctaatgattt ataactccct cttatatctc
     2761 aaatgcgttt atatatctat aatataatac ttcttttctt tttataatta tactatatat
     2821 caactttatt atctatttaa attgttttaa actaaaatct tattagatat aaatgtttaa
     2881 agtacacaac aaaatagtgg gatttatatt aaccccacta ctttacttaa aactatatac
     2941 atatttaaaa atattttatt cttacatatt gtttttatct tgattcttat tactttgtga
     3001 tatattttga attttctcca atactctagg agttatagat aatatattat ccactagatt
     3061 gatattacta tctaaactca ttattctagt ctctccactt tcaactacta caaatgctac
     3121 tggttgtaca gatatagccc ctgcgctacc tccagcaaaa ttcgtatctg atttttcatt
     3181 ttttaattca atttccctat ctttatcatc atatcctttt gagtattctc ctcctcctat
     3241 accaaagcca attgtaacct ttgatatagg tacaaccact gtagtatctg tttttatagg
     3301 gtctcctata atagtatttg catctataga acctttaatt gtttcaagag ttgtttccat
     3361 aagactctgt atcgaacctg ttgctctcat tactatcacc ttccttattt cctttatttt
     3421 tattcataat tttattaatc attattataa tattaaataa agcttttatt cttggcctta
     3481 tatgtatcct tatatttcct aaaacataat cttttgtgaa atctggattt acatttaaat
     3541 acattttttc tgcatcaatc atattaaata aatttccata caaagtattt atcaatacat
     3601 atacagaaga tgttaagcca atatttccag ttccaaaatt aatatttgaa taaagttcat
     3661 gtatttttat cttttttaat aatctataaa tgctcaaaag gtcatcagct aataatatac
     3721 ttgaatctat attattcttc atcccctctt ttttatcatt atttttacta ttttcagctg
     3781 gataaagttg tctatttata tttattaaat taaacatgta ttttatatta agctttaaac
     3841 aaatatcttt gttttttata tcagctatta ttaagatgtt tatatgagat attaaaatca
     3901 acatagttac acttataata aaaattacag ctattattaa atacttaaaa ttaaataatt
     3961 cattaagctc catgtttata ttatcatcaa aaaattacta tttatactta attatccata
     4021 tttattttaa gagaattata attttatatt tatacaaaaa aacacaacaa cttagagcat
     4081 tttaaatctt ttaaaattta aaattacata ctaaattatt gtgattttat atttttattc
     4141 atttgttgcc acttcttgat aattttctat aggtggcaat tcttcaagac tttctatatt
     4201 caacaacttt aaaaattcat ctgttgtttt ataaattatt ggtttcccta tcttattcaa
     4261 tctaccagct tctcttataa gttcattttc aaacaaagtt tgtaatacct tatcacattt
     4321 tactcctctt atatcctcta tttctacctt tgttattggt tgtttgtagg caattatagt
     4381 aagagtttct aatgtagctt ggctcaaact tttctttttc tttggttcaa taatcttctt
     4441 tatatattct gcatagtctt tatttgtaca catttggtac ttattctcta acttgattat
     4501 ttgaatacct ctattttgtt ctctgtactc ctcaataagt aaatttaaca taatctctat
     4561 ttcttttgat gaaagttctt tatttattat atagtttaat tcttttatac ttattggttc
     4621 accatatgca aacataacag attctataat atactttata tcttctcttt tcattttaac
     4681 actccgaact ttttcttatt agaatatcat caaaaaatat atcttgtact acgactattt
     4741 ctttttcttt tataagctct aatatagata aaaaagtagc tattatttca tcattttcat
     4801 atgattttat aatatttgta aaagtaactt caatcttctc ttttataata tctcttatat
     4861 ataatatttt ttcttctaca gatattattt tcttccttac tattttatct agtttctcat
     4921 cattagcatt ttctatctgt gatgttttaa ctttaaatat gtatggaagt atatttttta
     4981 ttgcttctat tgatatatct tctaaatcca cattgtcatc aataattatc tcttctttat
     5041 ttctataaaa tctctcatta acataagtta tattttcttt tatatcttgt gatgctacct
     5101 taaactttct atattcttct aacttttcca taagttctat tcttgggtct tcttcttcat
     5161 ctttttgctt ataaagcaga tatttagact ttatctctaa aagttttgat gccatagtta
     5221 taaattcact agttatctct aaatccattt tatctagcat tttcaaataa tttagatact
     5281 gcttagttat atctattatg gatatatcct ttatatctat tttatgcttt gttattaaat
     5341 cataaagtaa atctaatggt ccctcataga cttgtaattg tatattatac ttcatatcaa
     5401 tccctcttta atctgtttat tatattaaac aaataaatat actattttta gcaacactgc
     5461 atatattggt gttaatatta ttctatacat accagtaaat aaagcaatta ataaaattat
     5521 ataactcatg ctttcaaatt tatacaaata ttcattccat ttatatggta caaatgtaga
     5581 tataactccc catccatcaa gtggaggtat cggaagtaag ttaaaagctg caaatccaat
     5641 actatataaa aacacatatt cagctattgt atttatagca tacatatgca catacttatt
     5701 gataattaca cacagtatag cagtcaaaac attacaaaaa acgcctgcaa gtgaaactat
     5761 caggtttcct atcttatagt ttttaaagtt atttggattt actggtactg gctttgccca
     5821 ccctatctta aggataaaca tagccaaaag acctattggg tcaacatgtc ttacaggatt
     5881 taatgtcatt ctaccataag ctttagctgt atcatctccc aataagtgag ctgaataagc
     5941 atggccaaac tcatgtattg atattgccat agctatacca actaaacttg ctactatttc
     6001 tcctatattc atacttaaca ttaatgtaca tctcctaaat taaattttta atattattat
     6061 aacaattaaa tagcttataa tcaaaattat tttacattat aataatttta acttctaggc
     6121 ataaaattaa aatttgcttt ttattttata acttttatta ttatatcata ttcattgtga
     6181 aaatataata attacaccta ctgtaagtgt aatattatat tgacatgaat tgacattatt
     6241 gtctcttagt caatattata caagaagtat aaaaaaatat gtgttacact ttgtataaca
     6301 tgaaaggagg ttacctaagt gagacaagaa gaacgcacag tatgctttga tagggaatta
     6361 aaaattgaag catatagatt taaaggcata atgcaaaaat tcccaaacca ttttcatgaa
     6421 cattatgtaa ttggttttat agaaaaaggt caaagatatt tatcttgtaa aaataaagag
     6481 tataccacaa gtactggaga tttgctactt tttaaccctt ttgatagtca tacttgtgaa
     6541 caaatagatg ataaagtact tgattacaga tgtattaata ttaagccaga aataatgaaa
     6601 aaaactgtct ttgaaattac aggtaaaaat tatttaccaa aatttaatca acctgttata
     6661 tttcgcagtg agctagtacc tctactacaa gaattacact atataatcat ggaagaagaa
     6721 ttggatttta aaaaggaaga gctttttttc ttcctaattg aacaattaat tgaagaacat
     6781 acagagccaa atttgcaatc taacttggaa aatacaaata tagaaattca agcagtatgt
     6841 gattatctag aaaataatta tgctgaacat atagtacttg acgaattaag cactatagca
     6901 ggtatgaata agtactctct acttcgtaat tttacgaaat taaaaggtat tacaccatat
     6961 agatacctag aaaatatacg ggtaaacaaa gctaaaaagc ttttagaaaa aggcgtagaa
     7021 cctatagatg ctgcgataca aacaggattt gtagaccaaa gtcactttac aaactttttt
     7081 aagaatttta ttggtcttac accaaagcag tatcaaaata tatttataaa tgatgattca
     7141 aacaacttta aataaggtaa aaaggagaaa taaaaatgga aactaaaaat tcaaaatgtg
     7201 tcatggtaat agacgaaaat ttaccaatgg gaattatatc caatacagca gctataatgg
     7261 gaattacact aggaaaacat gccccagaaa ctgttggccc agatgtaatt gacaaaacag
     7321 gtaatagcca cttaggaatt attgacattc ctgtacctat tttaaaagga aacaaagaaa
     7381 taataaaaga tttacgtaaa aaattatata ctttggaatt taacgattta actgttgtag
     7441 atttttcaga tgtagcacaa agttgcaatc tttatgaaga atttacacaa aagattgcta
     7501 gtgttccaga agatgagtta cagtattttg ggatagcaat ttatgggaat aaaaagaaag
     7561 tgaataaact tactggtagt atgcctttac ttagataatt gttaaacaac cctatatatg
     7621 atattaaatc aaatgatatt ttaagataca taaacttttc tatatttcta taaaaatcat
     7681 aagattataa aatacttcta tatggtaaat aaaaataccc ctatggcaaa taattacata
     7741 agggtatttt ttatgtgtat tataatcata tctttgtgta ttataattat atttcatctg
     7801 ataattattt atatcatatt atcaattatt ctttgaagca tttgtagata gcttgcctta
     7861 tttatatcct tagtatttat caattccact tcgcctatta cttttttatc tttacatatc
     7921 tttatttttc ctaaaacagt tcccttttta attggcatct taggattttt tactatttca
     7981 attttcttct caaattcttt agaacttcct tttttaataa gagcatttaa atcttcttta
     8041 gcaaccaatt taactttgtt ttcatcagcc ttatccaatg taagtgttgc tatattatca
     8101 cctttactac ataacttaac actttcataa ttagcaaatc cataatttaa aaggctagag
     8161 gcatcattaa atctttctgg agaagtctct gctcctaaag ttgcagcaac tagatgagta
     8221 ttacctctct ttgcagatgc tgataaacag tattttgctt cttgagtaaa accagtttta
     8281 acaccagttg ctccttgata atgctttata agtttattag tatttgcaag acctactgta
     8341 acttgtttct tccctactac aaccttatcc atccatgtag ttaagtattt acttatcatt
     8401 tcgtgtttta atagttctct agacattaaa gctatatcat gagcagatgt atagtggttt
     8461 gcaactggaa gtccatttgt atttgcaaaa tgagtatcat tcatatttaa ctcttttgct
     8521 ttagcattca ttctatcaac aaatccttca acacttccag ctaagtgttc agccatagca
     8581 acacaagcat catttgcaga agcaacagct atacctttta ataatgtatc aaccttttga
     8641 gtttctcctg gctctaggaa tatttgacta ccacccatac tagatgcagt ttcacttact
     8701 tgaacttcat catcaagctt aatcttgcct gaatccaaag cttctactat aagtagcata
     8761 gtcattacct tagttacact agcaggagga agctttttat gagcatcctt ttcatataaa
     8821 atttgtccac taccaacatc catcaaaatt gctgattttg aagatatatt tagttggttg
     8881 gcatcagcat tttccttatt atttgcaaaa gaaaagctta aaggagtaag cgcaattaat
     8941 atagccaaag cagtactagc taattttttc atcgatgtca cctcttaaag tttatttaaa
     9001 cttattttct cacatttaac tttttttatt ctaaatgcct agatatacct tgacctaaat
     9061 tttttttctt ttcaagcttt ttaaagtaac cttctaaaac acctttatta gacgcatttt
     9121 ctattatttc aaaagcatct tcataattca ttccatactc tcctgctatt tccatttttg
     9181 tttgttttaa agcttttata gcattttgtc ttgaaacatc atccataaga atcctcctat
     9241 cagtaaaatt tatatataag tagtttttac taataaaaga ttgttataat tggtatttta
     9301 tgtaatatat atttttttaa aatgagtatt aaaaagacct cttgtaattc ttaagataat
     9361 atcaattgga tttttgatat tactttaaaa attacaagag gtctaatttt caaatttata
     9421 gtttttttat attatacttc cattatgata ggaagtatca ttggatttcg tttagttttt
     9481 tgatataaat attcttttag gttttcttta atattattct ttaaataagc ccattcttta
     9541 atatttttct cttcacattc atttagaaca ttcttaatta tatcctttgc tccatccatt
     9601 aaatcttctg actctcttac atatacgaat cctctggaaa ttatatctgg acctgctaag
     9661 accttaccct catccttgga aatagtaact acaactatca taagaccatc ttctgataaa
     9721 tgctttctat cccttaaaac tatattacct acatcgccta ctcctagacc atcaactaat
     9781 atgtttcctg tttgtatacg gtttgctacc ttagcagaat ttttatctaa ttctaaaaca
     9841 tctcctgttt gcatgacaaa aatattttct ttatccatac caagctgttc agctatttca
     9901 gcatgtcttt ttaacattct atattcacca tgagctggca taaaaaactt tggtctaact
     9961 aatgcatgta taagttttaa ttcttcttga caggcatgtc cagaaacgtg tatatcagct
    10021 atatcactgt atactacttc tgctcctttt tcaaataaga aattgattac tcttgatatt
    10081 aatttttcat ttcctggtat tggatgagca gatattataa ctaaatcgcc actctttatt
    10141 tctacttttt tgtgctctga aaaagccatt ctagcaagag ctgacatagg ttcaccttgt
    10201 gaaccagttg ttattatcac taattcacta tcttcatact tacatatatc atttaaatct
    10261 ataagcatgt catcagaaat atctaggtat cctaattctt ttgcaactcc aactacattg
    10321 accattgagc gacctgatat agcaactttt ctattaaact tttcagcagt atttattatt
    10381 tgttgtaatc tgtgtatgtt ggatgcaaag gtagcaacta taattcttct gccatttcct
    10441 tttgcaaata attcgtcaag acctacccca acagtctttt cagacatagt aaatcctggt
    10501 ttttctgcat tagtactatc tgccagcatt aaaagaactc cttttttgct caactcacag
    10561 attctatgca tatccataac atctccatca ataggagtca agtcaatctt aaaatctcct
    10621 gtgtggtata ttataccttg gtctgtgtgt attgcaatag agtaagcatc tggtatacta
    10681 tggttatttt tcaaaaactc tacttccata ttatcaagct ttataacttg tctaggacct
    10741 ataacattta acttaacatt attcatttta tgttctttaa gttttacttg tataagacct
    10801 atactaagtc ttgccccata tacaggtaca tttattttct ttaatatata tggaagagct
    10861 cctatatggt cttcatgtcc atgtgtaata aatataccct ttattttatc cctatttttt
    10921 actaaataag ttatatctgg tataactata tctactccta acatttcatc ctctggaaaa
    10981 ctaagtccag catctataac aattatttca tctttatact caacaacagt catatttttt
    11041 ccaacttcgt taagtccacc caaggccatt acctttatct tgttggtgtt ctttttgaac
    11101 aattgcatca tctccttctg tctatttaat tttttaacac gttctacaat cataaataat
    11161 atcaaatcac gcactcgcta ccagttattc ttattgtacc ataattcgta tcatatttta
    11221 agctatattt aaaatacatt taacgtatta ttttgacaaa cctattttat tttgatatcc
    11281 tctaaatatt atatgattta atatcggata atttaggagg atttatgcgt ggtaaaactc
    11341 attgtgcaat aggaatctta acagctatcc aaacatcttt aatatttaaa attcctatat
    11401 ctttagttga tattttagtt tcagctactt ttgctgtact acccgatttg gataaatcta
    11461 attctatggt ctcaaatttc attctaaaaa acaatgtatc caaatacata tatagaattt
    11521 ttatatatgc tgttaatatt attattttct ttatttcaat aaatataaat gataattttt
    11581 atttaagcgc aataattaca tttgttgcaa ttataattat tgaggcaaaa ctaacccaca
    11641 catttctaag aaaagttttt ctatcattaa tatttatact attagctata tgcttataca
    11701 tcatagaagt tgaaatatat tttacaattt tttgtctaat gttgtcaatt tttccctggt
    11761 taaagcacag aagtttttct catagcatat ttgcaactat aatagtatat tttttactaa
    11821 aacaaataga attaatcact aatattaata atttatcttt ttatggtacg attggttatg
    11881 caagtcatat gtttttagga gatttattta caaagcaagg aataccaatt ttttatccgc
    11941 taagcgaaaa gaaaatttct ttaggttttt taactgttgg aggaccattt agtaatttca
    12001 tagaaaaatc attcattttt gtacttatag gattaattat attttcaata ttaaaactat
    12061 aagcatcttg aaaactgtat atttgcattt tatagatggt ttataataaa aaatggaaga
    12121 atagcataga atataaaagt tctatactat tcttccatcg acattaagca atagaagttt
    12181 attcttctga atcgcttact ccattacact cgtcacatag tccataaaat ttaacatcat
    12241 gatcaagtat tttaaatttg tacaatgatt gtatctcttt ttctatattg tctaaaaggt
    12301 cttctttagc ttccattatc tttccacaat ttttacaaat aagatgatga tgattatgac
    12361 agtcttcttt atgtagacta atctcatatc ttatacatcc atcgtctaag tttagttttg
    12421 atattaatcc tatttcatcc aatagctgca ttgttctata tacagtagct aagcctattt
    12481 caggacagtc aaccctaact aaatcataga tttcctcact acttagatgt gaatggtcat
    12541 gtttaagcaa tatttcaact attgctcttc tttgtggcgt aatcttaaaa ccagtttctt
    12601 ttaacttgtc ttttaataaa tccattgtat ttgccataac atcaccctta ctattttcaa
    12661 ttgataatct ttattaaata atattgtaat tgataattca ttttttgtca agacatttaa
    12721 ataaatttaa tttattctca taatataaat atatacccat aaaagatata ttattcacca
    12781 aaattcataa attttttggt atttttaata aaaaacaaaa aaacagatat atactataaa
    12841 tgcttttaca attaataatg tttaattaaa gcaaatataa taaatatctg atttttatat
    12901 acaaacttaa ttacttatct agttaagtcc atttgattca tcttcgtcgt aatttaaacc
    12961 ttcttcttcc attatagcag tatacacagc tacaacagtt tcatactctt catcactttc
    13021 caaaggtatt aagatttcac cttcttcatc ctcatcaatt ctaaagatta aagcttcttc
    13081 agcttcttca tcatctaaag gcattaatat tgcatactct tttccttctg cttctaatgt
    13141 taatattatt tcaaattggc tttcaacgcc attttcgtct attaaattta ttatattttc
    13201 ttccataatg tcattcacct caaatttatt tttattttta ttatttatat tatatatcat
    13261 aagtattcaa ttttatagtt cttttatgaa tttattttaa aatctaaata tccttgcaaa
    13321 attattactg ctgccaacat atctataacc ttttttcttt tttgtctact aacatctgct
    13381 tctaataaag acctctctgc cgctactgta gaaagcctct catcccaaaa ctctacatca
    13441 atacctgttt ctgcttttac caattcacaa aacttgatta ctttttctcc ttgtggacct
    13501 aaagttccat tcatattttt tggtaatcct gatacaattt tatttacttg tttttctttt
    13561 attattgctt ttagctcttc aatatctttt ttcttgccaa ctctttttat tgtttttaca
    13621 ccttgtgcag ttaatcccat caaatcactc acagcaactc caatagtttt atcaccaaca
    13681 tcaagaccca ttattcttcc atctaacata gttcctcctt tatctattta tattctatag
    13741 attaaataca tattctgaac ctctcataac taaggtcaca ggcttactgc ttcatataat
    13801 tttacataat caatcataaa aattgcaata tgatttttta tgtaagcatc cagtttacat
    13861 taataatcat attgcatttt ttatttaaat cctatatgaa cagtaaaaat ttttttagtt
    13921 atttttttca aatattatca tatttatact tattattatt agtggtataa gtatatatat
    13981 agatgctgta gatgcagcaa ctattccaga atcattaact aaaagtgtaa ttatacaacc
    14041 aaccatagat gcaataaacc ctttaaacaa gattggaaaa ttattcatta tctttctaaa
    14101 gtgtctagat ggtttaaata taagcactgc aattactcca attcctacaa gtaaaatatt
    14161 tacccataca cttgtctgtg ctagttgcat attcatttga atttttcttc caaatgtttg
    14221 taatatctct cctggtccat ttaggaaaat tctctgtaca aacataccta aatgagattc
    14281 actacctgaa agtatatcta aagctgcaaa tgcaaaaacg acaactacag ctgaaacagc
    14341 taataataca gctttcttaa aatctatttt aatgtcatat ataagcatta taaacaacaa
    14401 atatgctaca cattctgata tagctccacc aacatttgca cccattgaag gatatgcact
    14461 agttataagt attattaatg aaaaaattac aacaagtaat ttagatacct tcttataatg
    14521 taataatact gctaagccaa atactgcact tgctatagtt acaccttcat attcatttcc
    14581 tacaccatag tacctagctc ctatgacagc atcataactc attatgttat tttgcattaa
    14641 gtatgttcca aatacagaat ctataactat gactaaaata gtaagtgttg caaaaaatcc
    14701 catgtgcttt atatcattgt ccttaaataa ttttctacct aacaagtata atattagcgt
    14761 agttgcaaat attcccaaag atattgaaat tggagtttta aaattcatca aaggagctaa
    14821 cataaatgat agtggcatta ttatgcctaa ttttataaac tccttaagta ctttgaatac
    14881 acgctcttta tgtggcatat aatttctaaa gaaaatcgca aacatggcaa ttacccaaga
    14941 agcagatatt acgcctacaa agccatttat aatagttgac cttattgaag atatagacac
    15001 tatcctttca taaagtgatt ttagatagct aatattgtcc tctttattta ctaaagtata
    15061 acttctacct accatctctt tattttcaag accaaatgta cctagtatat ctactccaac
    15121 atctaaattg gcaacaattc cagcctttct tgttgtggca gattccagta gacctttccc
    15181 ttctccacta aattttatta ttggagaaag tcttctctta ttcttataat ctaggtcact
    15241 tggaaatgca cttgctatat aaacagtgtc attttctcca accatagaaa atacttgttc
    15301 aagatattta tttatatttt ttacaatatt tttcttcatt atatcataag tattatcatt
    15361 tagatttaat ctatacatat ctaatctata tgtatctcca agttctacaa atatagcatc
    15421 actattttta taggattttt tagtttcatc tagtaattta tcataatctg tagatattcc
    15481 aaatggcatt ttagaatctt tcttattaat attatcaata ttacctgaat caatccttcc
    15541 atattggtcc atagctacta aacataagtt tctgttttta actaattgat tattttcaat
    15601 tatatcagca tttccaatta cagatgtctt taaaccattt tctgataaag tttttcctaa
    15661 tgaccctaaa tttgctccat attctccata ctcaagattt tcatttatag atctattaat
    15721 gcctaaatca tttatttctt tagctttttg acctgttgcg acttcaaaag ctttagcagt
    15781 atcttggtct actttttgaa aattgatata gtcttcagta gttacactag ctcttgttcc
    15841 tgcacccata cttgcataag accttctatc atcagtacct tgatcccctc ttatattcat
    15901 gagagctaca tagcctctct tttctatctc atttttcaag attggaatat tcatcatact
    15961 tccaagattg gtcctattca tatcaataaa tatgaccttg cctttttctt cagcaaaacc
    16021 atagctagca gttgatacaa aaatcataat gactattgca aacaacgaca taatcttttt
    16081 tctcatttat ttgacctact ttctattcag atagtgcgtg attacttctt caagtatctc
    16141 atctctttca aattttttaa ttatagctct tgcattttta tgactagtta tatagctaga
    16201 atcaccagaa aggagatacc ctataatttg atttataggg ttatatcctt tttcaactaa
    16261 tgctttatat acaaaatcaa tagtatctcc tacactcatc ctatcttctg gtattccttc
    16321 aaatttcata gtgtagtcta aatctttttc caaactaaaa acctccttga gtgaatgtta
    16381 tttaacttgt gtcttaataa cctcacttgc atagcttaaa gcttggtcaa ccttagatac
    16441 atcactagct cctgcttgtg ccatattagg tcttcctcca ccttttcctc cagctatttt
    16501 tgcaacttct ctaacaatat tacctgaatg tattccctta tctaatacat ctttagtggc
    16561 agtaactaca aagttaactt tatcatctac tacatttgca agtactacta caccagaacc
    16621 aagcttatct cttagattat ctgctgtttc tcttagtgta tccatatcca taccttcaaa
    16681 tttattagtt atcaaattaa ctccatttac ttcaacttta gaatcaaaaa tagaatcaac
    16741 tgattgtaaa ctcatcttag ctttcatatc atgcaattct ttagataagt ttttattttc
    16801 ttctaataaa gaacttattc tttgaattaa attatcttct ttagatttta agtttacaca
    16861 aacttcagag ataattccat ctctttcttt taggtattca taaacagctt ttcctgttat
    16921 tgcttctatt cttcttacac ctgctgctac tccaccttca gataatattt tgaacattcc
    16981 tacttgagaa gtatttgtca agtgagttcc tccacaaagt tctgtagaat aatctcccat
    17041 agaaactact cttacctcat caccatattt ttcaccaaat agtgctgtag ctcctttttc
    17101 tttagcttcc tttatattca taatatcaca ttttatgtct aaagatgata aaataacatt
    17161 atttactttt tcttctatta cttttaattc ttcatttgat atcgcttcaa agtgagtaat
    17221 atcaaatcta agtctttctg gagttactaa agaaccagct tgattaacat gttctcctaa
    17281 tacttctctt aatgccttat gaagtaaatg tgtagcactg tgatttcttg cagctgacat
    17341 tctagtttct ctatctacga gtgtcttcac tttgtcccca ttacttattc ttcctgattt
    17401 tattatacct atatgtttta tactattatt agcacctttt ttagtattta atacttctaa
    17461 aactaagttt tcattagtta tcaatccaca atctccaact tgtcctccac cttcaggata
    17521 gaaagtagtg ttatctagta ctatagatac cttatcgcct tcttctgcac tttgaactag
    17581 ctcatcatct ttaactatag cttcaatagt tccttcacca taaatttcac tatacccatt
    17641 aaatgtactg tcaactgtag attctaattt tgatagaggg tcttccttcc aactttctcc
    17701 atccatattt cctctagcat ttctagctct ttctttttgc ttttccattt cttcattaaa
    17761 agcttcttca tctacagata gatgttcttc ttctaatatt tctttagtta agtctatagg
    17821 gaagccataa gtatcatata gtttaaaagc ttcttgacca cttaggacag tctttccttc
    17881 attttttaat acttctatat aagagttcaa tatttctgtt ccttggtcta tagtttcatt
    17941 gaatttttct tcttctattc caactacttt tttaatataa ctttcttttt caactaaaac
    18001 tggatatgct ttatcattta cttttataac ttcatctatt agtttctgta aaaataattc
    18061 ttttactcct aataacttac catgacgagc agcacgtcta aggagtcttc taagaacata
    18121 tcctcttcct tcatttgatg gaagcactcc atcactaact aagaatgtta cagctcttat
    18181 atggtcagtt attattctta ttgatatatc attttttgga ttctctccat attttactcc
    18241 tgttaacttc tcaactgctt ctagtataga tttaattgta tcaacttcaa agatagtgtc
    18301 tacgccttgc ataatacatc ccattctttc aagacccata cctgtatcta tattcttgtt
    18361 ttctaataga ctataatttc cttcttcatc tctatcaaat tgagtaaata catggttcca
    18421 aaattctaaa tacctatcac aatcacagcc tggtttacag tctggattgt cacatccata
    18481 ttcttctcct ctatcaaaat atatttctga acaaggacca caaggacctg tacctatttc
    18541 ccagaaatta tcatcttttc caagtctaac cattctttct tctgggaaat tcatttcttt
    18601 tgcccatata tcataagaat catcatcttc ttcatataca gtcacccata tcttatcttc
    18661 tggtatattt agccattctg taacaaattc ccatccccat tttattgact ctcttttaaa
    18721 gtaatctcca aatgagaaat tacccatcat ttcaaagaat gtagcatgtc ttgcagttat
    18781 acctacattt tctatatctc ctgttcttat acatttttga gatgtacaca ttctcacact
    18841 tggaggtact tctacacctg aaaagtagtt tttcaaaggt gccatacctg agtttataag
    18901 taacaaactc ttatcattgt ttggtactaa agaataacta tttgctacat aatgaccttt
    18961 tgactcaaaa aattctaaaa acttacttct tatttcattt aatcccatct tttccatatc
    19021 atgttcctcc taataaattt tattttttcg tttaaataaa aaacctcgtc cctataaata
    19081 aatttatagg ggcgaggaca atcgcggtac caccctaatt atcatacaaa gtatgatatc
    19141 ttcggaaaac cttagctata acgtaactac cgtcaatctc tacttaaatc ttctttataa
    19201 aagataaatt gttcaagatt gctactaaaa ggctgcttca aatatcatat tctaagggct
    19261 tccagcattt ccctctctct gtaagacatc aaatatttta ctattcctta tcactgtatt
    19321 tgttttttaa ttaatatact aattatatta ctaaatttta caaaattaat caatactata
    19381 ttttcatata caataaattt attttataaa ctttatttac tcttaatata ctttattgct
    19441 tattttttta attttttaga tgtttttata aacttttctc gattatacct ccacctacta
    19501 caatatctcc atcatacatt actacagatt gacctttagt aatagctctt tgagcttcat
    19561 caaaaactat tttaatagta tcttctccta ctctatgaat agtagctggt gatggttttg
    19621 ctgaatatct tattttggct tgaactctta agggttcttc taacgtatct attgatataa
    19681 agttaacatc tttagcaata agttcctttt taaataaatc ttcattgtct ccaagaacta
    19741 tggtattatt tattggattt atgtctatta caaacattgg ttttccaaaa gtaattccaa
    19801 gcccttttct ttggcctata gtataatata atataccctt atgttttcca agtatattgc
    19861 ctttagtatc tacaaaaaaa ccttcttcaa tacgcttttt agaatgtttt tttacataat
    19921 ttgcatagtc attatcttta acaaaacaaa tttcttgact atcaggctta ttgtgtactg
    19981 ccatacccat ttccttagca atttctctta ctctatcttt ttcatagtca cctattggca
    20041 ataaagtatg ctctagttgc tcttgtgtaa gattataaag tgcataagtt tggtcttttt
    20101 tatctgtaac agattttttt agcaaatatc ttcctgtact ttcatccttt tctatctttg
    20161 catagtgacc tgtagctaca taatcacaac ctatttgtct agccttctta taaaaatcat
    20221 caaattttat atgtttatta caagctatac agggattagg agtttttcct tccaaatatt
    20281 catctataaa ataatctatt actttttctt taaacacttc tctaaaattt aaaacataaa
    20341 atggtatacc tattttattt gctacccttc tagcatcttc aacagcagat aaagagcaac
    20401 aaccaccttc aatttcaaca acatcatcat cttgccacaa cttcatagta acaccaatga
    20461 catcatatcc ttgttgtttt aaaagatatg cagctacaga gctatcaact cctccactca
    20521 tacctatcat tactttttta ttcataaaca aatttcacct catcttttgc attacttatt
    20581 attataccat atagagcaag tattgtactt atttaaaata tagcttgttc tattttctaa
    20641 aaaaataatc atctttatta tttgaatctt atggattatt ttgttaacta attaacctct
    20701 aaatcaagtt aaaatactta atttaggcaa taaaaaatag ctattttaaa aacagctatt
    20761 ttttatgtcc taattatatc attagtactt ctttttaatc attgtaaact tctcataaca
    20821 caatcactta tttttattct tcttcttcaa catcatggtc atgagcatca tctataacat
    20881 atccatccaa ttctggtata tggatattgt tcttttgagc ataatctata agagctgctt
    20941 ttacagcttg ttcagctaaa actgaacaat gcatctttac tggtggtaaa ccatccaaag
    21001 cttctgcaac agctttattt gtaagttcta atgcatcttt tatagttttt ccttttatca
    21061 tttcagttgc catagaagaa cttgctatag ctgaaccaca gccaaatgtt ttaaacttaa
    21121 catcctttat tacatctcca tctatgtcta aaaatatctt cattatatct ccacatgtag
    21181 ggtttccaac ttcacctaca ccacttgcat tatcaatttc tcccatattt cttggattca
    21241 taaaatgttc cataacttta tcactatatt gcattatctt ttcctcctac tcaatttatg
    21301 tctatttttt atgctttatc tttatgtcta ttttactaaa ccttgtttct tcgcatcatc
    21361 ataaagtggt gacatgcttc taagtctttc tattactttt ggtaagttct ctagtatata
    21421 atctatatca tcatctgttg taaaatctcc aactgtaagt cttaatgaac catgtgctat
    21481 ttcatgtggt aaacctattg caagaagtac atgtgaaggg tctaatgaac cagaagtaca
    21541 tgcagaacca cttgaaccag caattcctaa catatctaat aataaaagta ttccttcacc
    21601 ttctataaat tggaatgcaa agtttgcatt tcctggcaat ctattttcta agctaccatt
    21661 tactcttgtg taaggtattc tttctaacac accatctatt aacttatttc taagacgagt
    21721 taaagtttct acatgatttt gcatattttc cttagctaat tctgctgctt ttccatatcc
    21781 aactattgca ggtatatttt ctgtaccagc tcttttgctt ttttcttgtg ctccaccatg
    21841 gacaaagtta tgaagtctta caccttttct tatgtataaa gctcctacac cttttggtcc
    21901 atatatttta tgtgaagaca tactcatcaa atctattcct aattctttaa catctactgg
    21961 aatattacct gtagcttgta ctgcatcagt gtggaataat atcttatgtt ttttagctat
    22021 ttcggatatt tctttaatag gctgtatagt tcctatttca ttatttgcaa acattatact
    22081 tataagtata gtagtatctt ttattgaatc ttctagttgc tttaagtcta cttttccttc
    22141 gctatcaaca tctaaataag ttatttcaaa tccatgatgt tttgctaagt attcacatgt
    22201 atgaagtatt gcatggtgct ctatttttga agttattata tgattacctt tgtttttatt
    22261 agcataagct acaccctcta gtgtccagtt atcactttct gaaccacctg ctgtaaaata
    22321 tatttcacta ggttcagcat ttataagggc tgctacttgt tctcttgctt tatccaaagc
    22381 atcttttgct tctcttccga atgtgtgaaa actagatgca ttaccaaaat aatctgttag
    22441 gtatggcatc attgcatcca atacttcttt tttaataggt gttgttgcag aataatccat
    22501 atacaatctt cttttttcca ttacattcat ctccaaatct attttttaat atttgttata
    22561 tcattttcta atttattttt gttatagtca tttatcatat ctttaagagt aattgaatct
    22621 ataacatctt ctataccctt tttcatcttt tcccaaacta tttttgttac acacatgttt
    22681 gagttttcac atacatcttc atctagtaca cagtcagata atgcaactgg tccttctaat
    22741 actacaagta tatctcctac tgttatgtct tcagcattct ttgaaagcaa ataacctcct
    22801 tgagcacctc tcacactttt tactagaccc gattttttta aagatgaaaa tatttgttct
    22861 aagtactgat ctgatatttt ttgcttctta gcaataaatt ttaatgatac tggtccattg
    22921 tcttgattta atgctaattc aaacattgct tttagtccat atctaccttt agtagacaac
    22981 ttcatatatt atcacctcta tatagaaatc taattcatac tgttttagta ggaattactt
    23041 tcaagataat tttattatac cctactaatt ttgtcaagat taattttaat tttttatttt
    23101 gaataaattc cccattttcc aatgttttca aatcctagtt ttttatatat ctttccagcc
    23161 tcttcattat cataaaacaa acaaggaatt ttgttttctc tcagtaactc tgaacatagt
    23221 ttaattaggc attttgtagc aagtccttta gctctatatt taggatgtgt tcctactcca
    23281 attatcattg catgagtcct attttctgaa gtactctttg ccattgacac cacctgtttg
    23341 ttaatctcta tacaatatcc tctacctgtc cttagtccat tttttaaatt ctctaaagtt
    23401 gtactgtgaa attcatctat taagtcataa agttttactg tcttttttag atttccaagc
    23461 ctaattctct taacctttgc attacaatta ttatctatca aaaacttttt agtttgaagt
    23521 ttgcaaaaat caactacctt taaattatta agtcctaatc tctttgctaa agcatctaca
    23581 gcacatattt tcccagatat ttcttcgtaa ttagtattac gaagtagatt ataaaaacct
    23641 tcaacatcat actctccatc agaataaaac atcataaatt caaaatattt aagtaatatt
    23701 gcctttattt caccatgttc acccacatct gcccatatat ttaaaaaatt atttccatat
    23761 ccatatcttt caatatcccc tattataaac aaattgtact caggttcttt ttttaagtat
    23821 ttcataactc tactgtgata agttgagtta agttttataa tcataatatc tacccccgat
    23881 acataaagtt cagtctaaaa atcactattt agatattcta aatatttttt tatatttttc
    23941 tcagttttat tttcttgtgg tatgtaataa atactatctt ttatgctatc tggtaaatac
    24001 tgttgcttta cataatgatt tttaaaatta tgaggatatt tgtatccaca acccctacct
    24061 atttctttag aaccagaata gtgagcatcc tttatactat ttggtatatc cttaacaaac
    24121 tctttatcca gttcatccat agctttcatt attgctatac atgcagaatt agactttgga
    24181 gatgtagcca aaagaatagt agcttctgct aatggtattt tcgcttctgg aaatccaagt
    24241 tgcatagctg agtctacaca tgcctttaca attacaatag catttggata agctaaacct
    24301 atatcttcac tagctattac taaaagtctc ctacatatac ttatcaaatc cccacctttt
    24361 ataagtcttg ctagatagtg tatagatgcc tgtgggtcac ttcctcttat agatttttga
    24421 aatgcactta aaatatcata atgactatca ccatttttgt catagtttat aattttatta
    24481 aatgtagatg cccttattac atctgaatct atataagtta tattatcctt atttggttta
    24541 gttgaataga ctaccacttc caaaatattt aaggctcttc tcatatctcc atcagaaaga
    24601 attgctatat cttcaatagc atcattatta cactcaatat ccatatagct atcttcattt
    24661 aatacttcaa cagctctttt cagtcctttt tctatatcaa gtttttctaa aggtttaaat
    24721 tcaaatacag tagacctact taaaagagct ttatatacat aatgatatgg attttctgta
    24781 gtgctagcaa tcaaagttat actcccattt tccataaatt ctaatattga ttgttgctgt
    24841 tttttattaa aactttgtat ttcatctata tataatagga ctccatttac attatttata
    24901 cttccaagct ctgatatcac cttttttata tcttctaaag atgaattagt agcatttatt
    24961 ttatagaagc ttttattgct tctttctgct attatttccg ctactgtagt tttaccaaca
    25021 ccaggaggac caaaaaatat catatttggt aaaaaattag attgtaatat cttagacaat
    25081 atttttccat tacctattat atgactttga cctattacat cattcattgt ttttggtctt
    25141 attttatctg ctaaaggcat tttctcactc ctttttaata tacttatcat taccttaata
    25201 attcgtctaa aaaaggtatc tatttgaaat agataccttt tctaatctaa acctataaaa
    25261 tatagattat tgattgtttt ttaatttttt taattcatct gtaagtttgt cattaagtat
    25321 tcttatatga gtacctttca tacctaatga tcttgattct atcacacctg cactctcaaa
    25381 ttttctaagt gcatttacta ttacagacct agttatacca actctatcag ctatcttact
    25441 tgctacaagt aaaccttctt ttccatccaa ttcagcaaaa atatgttcaa ctgcttcaag
    25501 ctcggagtag gacagagtgc ctattgccat ttgaactaca gctttctttc tcatttcttc
    25561 ttccaattcc tcacctattg ctcttaatat ttcaagacca acaacagttg cactgtattc
    25621 agctattact aaatcatcat cattgaatga atttgaatat cttgaaagta ccaatgttcc
    25681 taatctttga ccgcttccta atattggaac tactgtagta tatttttgta atcttccatg
    25741 ttcttcagga aagatttcta atatcttctc accatttaaa ttttctaatg tttcatcaat
    25801 ttttaacaca ttttgagtat attcatctga aaatttcttt tgcttagtat actcatcttc
    25861 tataactgaa ctgtcttgaa catcatttaa atgaagacct agtactttac cttttgcact
    25921 tactacataa acattagaac ttaaaacgtc gcccaatgct ccggccagta aatcaaaaga
    25981 gacactgctt ccaccacttg tttgtaatgt tttatttatt ttccttgttt tttgtaacac
    26041 ttcacttgcc atttaatcat ctcctcatga aatttaggcc ttttaataac cttttatatt
    26101 ttctaatatt attttcacat ttaatgaaaa tttatttttc tattagttgt ttacacttga
    26161 aagattatca tagattggaa cctttttcaa gagaattatg tgattttttt caattttcac
    26221 tcttttccgt cattatgctc ttttgtctct ttattacatt ctttattaga acacactgtt
    26281 tttgtttcag atttagtcac tttttcaacc atatatgaac cacacttctc acaaaactct
    26341 cctgttggct tattccaagc tacaaagtca cagtttggat aattagaaca cccataaaaa
    26401 gctttacctc ttttagattt tctaagtata atatctcctt cttcacattt tggacattta
    26461 acaccaattt tattcataat tggtctagtt gttttacaat cgggatagtt tttacaagcc
    26521 ataaactttc caaatctacc atatttgata accatattag aaccacagtt ctcgcaaatc
    26581 tcatcagttt cttcatccat atttactttt tctatatttt caagagcttc ttcaatagcc
    26641 tctttaagtg gtgcatatga ttctgataca atctttttcc aatctgtatt gccttcttct
    26701 ataacatcaa gtttactttc catatcagca gtaaaatcta catctataaa tttatggaaa
    26761 ttattttcca aaatatcagt aactattatt ccaagttctg ttggacatag acttgttcct
    26821 tgcttttcaa catactctct attcagtata gtagctattg ttggagcata cgtacttggt
    26881 ctacctatac ctagttcttc tagtgttttt actaaactag cttctgtata tcttgctggt
    26941 ggttgtgtaa aatgttggtc tggcaatata ttttctatat ttaatatatc tcctttttct
    27001 atacttggta aaattttgtc ttctctttct gaaaaattat ataccttggt ataaccatca
    27061 aatttcattt ttgaaccagt tgccttaaat acaatatcgc ctattttaca ttctacattt
    27121 agtatatcaa acactgaatc ttccatttga ctagctacaa atcttctcca aattaaattg
    27181 tataacttgt actggtcttt gctcaatgag gcttttatac tctcaggagt tctatcaact
    27241 gaggttggtc ttattgcctc atgggcatct tgaacctttt tagtatcctt tttttctttt
    27301 ttatcaccaa tgtttttata gtagttttct cctaaattgt ttacgatata acccttagct
    27361 ttttcttttg cttcatcaga tattctttta gagtcagttc ttatatatga tataagacca
    27421 acagtacctt caccttctat gtcgatacct tcatataatt cttgtgctat catcattgtt
    27481 tttttagtag taaaaaataa cttatttgct ccttcttgtt gaagcatact tgttgtaaat
    27541 ggttttggag ctgatttacg tcttgattta gattctatct tctcaacctt taaatcttta
    27601 ccttccattt cttttagtat ttcatttaca gcttcttcat tttctaattc aatcttttca
    27661 tcatttttac cataaaattt caaagttata tctttgtctt ttactgtctt agcctcaaca
    27721 tctattgtcc agtattcttt tggaataaat gcctttattt ctttttctct atcacaaatt
    27781 aactttgttg taacagattg cactctacct gcactaagac cttttctaac cttttgccat
    27841 aatataggac ttatttgata acctaaaagt ctgtctagca ctcttcttgc ctgttgtgca
    27901 tcaaccaaat ttatatcaat atttctagga tgtttaattg cttttttaat tgcatcctta
    27961 gttatctcat taaactctat tctacaatcc tcagattcat ctaaatttag tatatgagct
    28021 aaatgccatg atatagcttc accttctcta tcagggtcag ttgctagata tacttgttta
    28081 gattttttag cttctttttt taattctttt attacatcgc cttttcctct tatatttata
    28141 tattgaggtt caaaattatt ttctatatct acacctaatt tacttttagg taaatctctg
    28201 acatgaccaa ctgatgcttt aactgtgtaa tgacttttcc ctaaaaattt ttctatagtt
    28261 ttagcttttg caggcgattc tacgatgact aatgttttgg ccataaaacc atacaccccc
    28321 actacctaat cttaatttat acatttaaac tgtacgtttt attattcatt tctactacta
    28381 actcatttag tactaattca ttgattattg aatttacata ctttatttct ataccagtat
    28441 aatcacaaat actatctata tgcaagtttc cttctctttt tatagcttca attatttgct
    28501 tagacttggc atttagactt atattatcat atttttgatt tattttttta tcaataatat
    28561 taaatatgtt atattcattt aaaatatcat ctatattttc aattaatttt gcaccttctt
    28621 ttataatttt atgacaacct ctactcattt gagaatttat attaccaggt attgcaaaaa
    28681 cattttttcc atgttcaaga gcaaaatcta ctgtgattag tgcaccactt tttattgctg
    28741 cttctacaac aactactcca tcacttaaac cactgataat tctatttcta ttagaaaaat
    28801 ggtacggggc tactgtcgag ttaatattat actctgataa taataatccc ccattttcta
    28861 atattttatt tgataaatgt aaattttgtt ttggaagagg attgtctact cctgaaccaa
    28921 gtactgctat agttttagat tttccactca tacaacctat gtgcgagtat gcatctattc
    28981 ctatagctaa tccacttact atattaactc catattggga tagttgacaa cttattgttt
    29041 ttgcacaatt aattccatag gctgtaggtt ttcttgaacc tactatagct atattaaaat
    29101 tattattaac taagcctatg tcacctttgt agaataataa ctttggagcg ttgtatatat
    29161 tctttaaatt ttcaggatat tctttatcat atttacaaat atatttaatc gcttttttgt
    29221 aaagtagttc ttttatattt tctaaataag cgtgacctct atattttact atattttttc
    29281 taatattcaa gcttatattt tttaaattat atatttcttt ttcagaaaaa tcaaatatat
    29341 cttcaatatt tactatttca ttttctatta tttcaattgt ttttgttgtt attccaccaa
    29401 ttgattttaa ccataaataa gtatctcttt tttccataaa atccacctca aaaaactatt
    29461 taaaataact ataataagcc tttctaaatg aaaaagcttc tataatacac tgtgaattta
    29521 tcaaatctct ttcttctaaa tctgctattg ttcttgccat ttttaaaagt tttgtataac
    29581 ttctactgct taggttgtat ttactaaata tcatctcagc cgtttttgaa gcttcttttt
    29641 ccagtttaca atatttaaat aaattgtaag ctttaatttc actattattt tttatattat
    29701 ctttcttaaa tctatttatc tgtatttttc tagcattttc tactcttctc tttatttttt
    29761 gagagctttc ttcttgtttt aaagaattaa aatctgaata ttttatagaa ttaacttcta
    29821 caaaaatatc aaacctatct aacaatggac ctgatatttt atttatgtat ctatcaattt
    29881 cgttacttct acatctacac tctgtctctg acatataata accacatgga catggattca
    29941 tagctgcaac taacagtact ctacaaggat attttgcact gtactttact ctggatatat
    30001 ttacatatcc atcttctata ggttgtctta aagtctcaag tatttttcta tcaaattcgg
    30061 ctatctcatc taaaaataag atacctctat gtgctaaagc aatttctcca ggtcttgcat
    30121 ccattcctcc tccaattaaa gattgctttg tagttgtatg atgaggtgct ctaaaaggtc
    30181 ttttatcaat tattccttta gtttcattta tcatacccaa tatactatag accttactta
    30241 cttctatcat ttcttctaca cttatatctg gtaaaattgt ccttactctt tttgcaatca
    30301 tagtttttcc tgagcctgga ggtccaatca taaacatatt atgatttcca gcagcagcaa
    30361 tttctgcact cctctttaca aaataatttc cttttacatc tttaaagtct tcatcatatt
    30421 tactttcttc attattaatc ttagtatatt tgcaatctat ataactatta tctttttcta
    30481 attcttcgtt ctcttttctt gacttatcat ccaaaaaaga cattatcctt actttatcga
    30541 cttttatctc ttcgtttaaa aaatcgacac attcttttaa acttttaata ggaattatat
    30601 caatttcatc tacaaataga ctttctttta tgttctcaat tggtataaaa atacgtttta
    30661 tgttctgagt ttttgcaccc ataattatgg gcaatatacc tcttactttt cttattttcc
    30721 catctaatga taattctcct ataaacatac tttctcttat gtaattttca tcttttttta
    30781 ttaactctct taaaaggcct atacttatag ataaatctaa aaaagctcct tcttttttta
    30841 tatctgctgg tgataaattt acaactattc tcgtgcttgg aaatttatat ccactattaa
    30901 gaattgctga ctttactctt tctcttgctt ctttaatttc tttgcctgga agaccaacaa
    30961 tattaaaact aggtattcca ttgcttacat ctacttcaac cttaactaaa aagctgtcga
    31021 ttcctactaa gttgcttgaa ttaataatac ttaacatatt taatcctttc caaaaacatt
    31081 atctttttta aaaagcattc attatgtgat ttattctttt ttctaataaa tatacctcta
    31141 taacatcaaa tcttatggga gtgttattta agttattttt tataatataa taatttgcaa
    31201 ctccaattat cttttttctt tttttgaagc ttacagattc acaagggtag ccaaacttta
    31261 tgttagacct tgatttcacc tccacaaata taatttcatc ttccattttt gctattatat
    31321 ctatttcccc tatctttaat ctgtaatttt tttctagtat ctttgctcct tttgatagca
    31381 aataattaac tgctactttt tctccaaaat cacctttttc tttattattc attattcact
    31441 ccaatacatt aaattttcac ttttaaatta tggtcagtat acaattttac tattcaagtt
    31501 tttggattga ttttatttcc atcaatatta ataaatactt ctattgactt tattctttta
    31561 tgatattatt ctagttttca taggaaaagt ttattttttt ggaggagtgc ctttaatgaa
    31621 cagagaaaaa ttagttgctt ttatacgata tttatcttta tttatattag ttgtaagcta
    31681 tttgaaaaat gttgaaaata cattgtatcc ggtcataact atgataatat tatttctaat
    31741 tataataaat aatcaagtta gatttttttc tttatcaaat gagaataaat ttatacttat
    31801 ttcttacttt ttagaactta tattaatttt tatactttgt aattatacaa aaacttttaa
    31861 ttcgatttac tttgttcctt taatattaga tatatcattt ttaataaagg aaaaatataa
    31921 gtacatattg ttctcttttg ttataatatc ttctcttatt attagtttag ataaaaatat
    31981 atatttggca ctggagtcaa gctctatatt gctaattata actgtacttt ctatatatat
    32041 agaaaatgag aatttatcaa aattatacag tcaaaatctt tatgataagc ttagaatttc
    32101 taaagatgaa ttaaaaaaag ttaatgctga tttggaaact tatgcaagtt ctatagaaga
    32161 attagcaatt ttaaaagaaa gaaatcgaat atcaagagaa atacatgata gtgtaggaca
    32221 ttctctttct acaacaataa tacaattaaa tgctatagaa aaactcttaa aagacaaacc
    32281 tctaatttat gacttagtac atgaacttag agaatttgta actgaaagtt ttcaagatgt
    32341 aagaagggct atatctgagt taaaacctgt tgaatatgaa aattaccaaa gtttatttaa
    32401 aatcaaagaa ttagttaaaa gctttattaa gcttacaaat attaatgtta aattaactat
    32461 ttcaaaaaat acttggaact tatccagaaa tcaatctata gctttatata gacttataca
    32521 ggaatccctt tccaactcat cgatgcatgg aaaggcaact gaaatcagaa tttttattac
    32581 attcaatact tcaaatctta taattactat tagtgataat ggtataggat gtggcaatat
    32641 aaaaaaagga aatggactta atagtatcaa tgagagaata tatgaattaa atggtaaagt
    32701 tgaatttgat aattctaata atggtttcac aattagagct tcttttccta aattttcagg
    32761 gggtgatttt tttgaataaa attaaagttc ttatagtaga tgacgaaaaa ttaattagaa
    32821 aaggtcttaa aattatatta tcatcttata atgatttaga aattgtagga gatgcttcta
    32881 atggatatga agctttagaa ttttgtaaaa tgaatgatgt agacatagtt cttatggata
    32941 tacgaatgaa agtatgtgat ggggttctag gtacaaggct tataaaggaa tataataatt
    33001 ctataacatt attaatttta acaactttta atgatgatga atatataaaa gatgctatga
    33061 agtttggtgc ttcaggatac cttttaaaag atagctctga tgaagtattg catgaaggga
    33121 ttcgttcttc attttttggc aatattgtgc ttgataaaag tgtagctgaa aaaatcatga
    33181 cctctgaaaa aacgattaaa caagagcatc tttatgacat gtacaattta acagaaaaag
    33241 aaatatctat aattagacta attgcaaatg gacttaataa taaagaaata agtcaagaac
    33301 tattcttatc tgaaggtaca ataaagaata acataactaa tattttagct aaactagaac
    33361 ttcgtgacag aactcaacta gcaatctttg ctttcaaaaa taaaattgta atagaataaa
    33421 tctaaaaata taaagtgact taagtcactt tttttagtga cttatagtaa tagaattata
    33481 attcacaatt ctttattata atattatagc tttttaactt atacaaaatt attttggagg
    33541 gattactatg gatatagtca gagtaaataa tataacaaaa agatttaatg ataaattagt
    33601 acttgataac atcagctttt ctgttaaaaa aggtgagata tttggactta ttggcccaaa
    33661 tggtgcaggt aaatctacac ttataaatat aattacaaat cttatgttac caaatagtgg
    33721 tagtattcaa atcaatggtt tagatttatc aaaagattat ataaaagcaa agtctataat
    33781 agggttagtt ccacaagaat tagcaattat agaaactctt accccttttg ataacttaga
    33841 gtactttgga gctttctacg gtttaaaggg aaaactactt aaagaaagaa tcattgaagc
    33901 attagaagtt acaggtctta ctgaagtcaa aaagaaaaag gtcaaaaaat tatctggtgg
    33961 tatgcaaagg agattaaata ttggaatagc actcttaaat catcctaaaa tattaatatt
    34021 ggatgaacca actgtaggtg tagaccccca atcaagaaat catattttca attttataaa
    34081 agatatatct aaaaaacatg aaactactgt aatatatact tcccattata tggaagaagt
    34141 tgagcacctt tgttctaaaa tttttattat ggatgaaggt aaagaaattg cttttggaaa
    34201 taatgattat ttaaaatcac tcgtatctac aaatacaaaa ttaattatgg aaataaaaaa
    34261 tataaatgcc caacttatct ttgatttaaa aaatactaaa ggtgttatat ctgttttaga
    34321 aaataattca ttattagaat tggatataga taaaaaatta caacttacag atatactctc
    34381 tgtcattgac aaaaacaatt caaaaataat gaaaatttct tatgaagaac ctagcctaga
    34441 agacgtattt ttaaatctaa caggaaaaaa tttaagggac taatggaggt gattttatga
    34501 aattatacat gagtgtaaaa actatgctaa agagtttaaa aagctccttt atacttaatt
    34561 taatatattt tttagctttg cctctgattt tatcttggtt tcttgggatg gttacagaaa
    34621 gcatgtttca aaaccctata aaaacagaat ctacccccat tgttatatat gacaaagata
    34681 acacaagatt atcaaatgat ttgacaaagt atttgaaaaa tgatttatct tatatattaa
    34741 cagttaaaaa agatgattct aaggcagaat taaagcttac tatacctaaa ggctatgaga
    34801 gtagtttatt aaatgaaaaa tcaaatactc taaacataga aaaacttgga actcgtgatg
    34861 atattgcaat attgcttcaa gatatattag atacttacca tgaaaaattt tatttaaata
    34921 attctcagaa aataagttca gaagattttt ctaaattatt taataaaaat tctattgata
    34981 cttctataat aaataacaat gttaaacaga gctcttatga atactttgct ttagtttcac
    35041 taggatttct tgtaataatt tttataatga acaatatttt gtcaaattat ataagtgaat
    35101 caaagggact ttcaaaaaga ctttattcta tgcctataac tagagtacaa ttcttaattt
    35161 atgactttgt aggtttatgg atttattcat ttatattctt attattatat gttttattct
    35221 ttagaatact tggaataaca tttaaaggta attttgccat attgctccta ctttgtgctt
    35281 tatcatctta ttttatgact tcaatatcta cctttgtaac cagctttttt agtaaaaaat
    35341 acggtacagc aatagtttat gcattactct ttttacagac aatttttgga ggtatcttca
    35401 gtatgataag tgatacattt actaagctta caagtttatc tcctacctat ttaataggag
    35461 aattgtttag taattatgaa acatttaaaa ccatagattc aataggaaat ttaattttca
    35521 catgtttaat tatctctaca atattaattg cacttgctat tgtaaaggaa aaatataaat
    35581 ggagggaggt ttaataatga ttagattaac tattgcaaat ataaaaagat atctaaaaaa
    35641 tcatactctt ttaattaata tggttatgct tcctattata ctaatttttt cacttaattt
    35701 ttttatcaac aactcgggaa atcaatcaat gtacttttct ccagtagcaa ttgtatctga
    35761 ctcttcagga aagtatgaac ataagttaat aaatagttct aaattaaaag aaaattcatt
    35821 tagattaaat gaacaagata aggctatgaa tctattaaaa aataataagg tttctgctgt
    35881 attcgtttta gataaaaatt tttcaaatag tatagataaa ttacaacgac ctgtagttaa
    35941 atgctttaaa attgaaaatg gtggtggtag tctttgggca gaatcacaaa tagaatcttt
    36001 tattactaaa tcgttaaaat tgaaagtgga taaaaatata gatgataaat tgacaaagac
    36061 aaatataatt gataacaaac cagataagaa taaaggttca tttttagtag tcttcttgat
    36121 atgctatttt atgtatatta atgcggcaca tcttgcttct gatttattta cattaaaaaa
    36181 atcaaatgtg ctaaaaagac ttatctctac agataataaa gatataaaaa taattttcag
    36241 tatattttta ggactatttt ttattcaatc aattgtatac acttttgctc tattatgttt
    36301 ttcaattata gaagacttta atttgagtct gaatgtattg atgattgtac tagcaaatag
    36361 ttttgtttcc actggatttg tattttgggt agctagagta tttaaaaatg aaagttctat
    36421 aagtcttata tctacatttt attctttaat aggtctagct atatctatct ctagtctaat
    36481 accatcaatg gataaattat cctttatgac taatctttca aagttcacac cattttattg
    36541 gactatagat gctattaaaa acaatggtag tattttaata aatataatag ctctaatatt
    36601 aattggaatt atatttgtaa ctgcaggaag tcttaaacta agagattttg ctaaaaacta
    36661 ataattatta aatataatta gtatctattt ttatataatt gtaaaagaat atttcaacat
    36721 attaaattat tttatcttat atttttctct ttagtttcac acatcaccaa gtctaaactc
    36781 tatattatat attaatattt ttgacttgtc aagttattta tgttataata ttaatcatta
    36841 gataattaaa gcattgtacc taagttgcaa tatctaaaat tcaatttgga ggtataacta
    36901 gcatatgtat aaaattggtg aaagtgtaat gtatccaaaa gagggagcct gctctgtaaa
    36961 tgatattgta acaaagaaaa taaatcatga gatgcaaaaa tactatgaat taagtgtcat
    37021 ttttaatagt aaccttaaaa tttcgattcc agttctaaat gcagatagaa ttggcatacg
    37081 tccagttatg gatggaaatg atgttgataa ttttatccaa tctattaata aaacagatgg
    37141 tgtatggatt tttgatagaa aagaaagact taaactgtac caagataaat ttcattcagg
    37201 agatgttttt gaaattgtaa aattaatcaa aatgcttatg atacaagaca gttcaaaaca
    37261 attgtgtagc acagataagg agtttttaaa taaagctcaa aaatttgctt tatcagaatt
    37321 agctgctgct caatgtaaat cctatacaat ggtattagag gaaatgaaaa aacatatatt
    37381 aaattcaaag aatacaaatt aaaccagttt tttaaactgg ttttattttt tatactaatc
    37441 atccatgcta ctttagctta ttttaaactg cctaatctaa tattaataaa gttatctcaa
    37501 ttagatagat gtattttatt caaataaaaa aaactaagag taaatcatat tactgattta
    37561 ctcttagcta ataaaattta atcttcttca agttcttttt tctcttgtaa taatacactt
    37621 aattcatttg cttctaaaac ttgtgcctct gcaatatcaa gtaactcttg ttgccattcc
    37681 acacatttat ctttgtaatc aaaaggtagc gttctgtcaa ctatgtactt atcaatacag
    37741 tcctccgcac ttttaattat ttcttttctt tcatcaataa atttttctaa ttctactaag
    37801 gcttcttcat aagcttttct actcatataa attccccctt tgtacaatta ttctacatta
    37861 aaatgatttt tcctcttttt tgtataaaat tttatttgta tataactttt ccatcaatat
    37921 cttttatagt ttgacatcca gttaatatca tagaactact tagctctgat tgaagtttat
    37981 ttacataagt ttctacacca tcagttgcac caccaaaaga agcagtcaca aaaggtcttc
    38041 ctattaatac tgcatctgca cctaaaccta tcatttttag tacgtctaaa ccagttctca
    38101 ctccaccatc tgcaagtatt gtaactttac ctttaacagc atcagcaatt tttggtaaaa
    38161 cttcacatgc tcctggtgta cagtcaagca ctcttcctcc atgatttgat acgactattg
    38221 catccacacc tgcttctact gccattaaag catcttcaac agtcattata cctttcaata
    38281 taaatggtag tttagtagac tttactaact cctttatttg tttaacattt ttaggaagta
    38341 ctggttttcc atgtaatgat aaagttacta gaccacaggc atctatatca actccaactg
    38401 caaatgcacc agcttcttca gctaatctta tcttttttat aatattttca ttatcccaag
    38461 gtttaataaa tacaattcca gctccattat actttttgac tacatctaaa ttttccatta
    38521 aaaaagcatc tactgccgta tcaccaacca ttgcataaat accactatta acacatcctg
    38581 caactactgg ttctatgtaa tctctttcat taatttttcc acccatattt aaagtagttc
    38641 ctgttactgg agctgcaaat ataggtgcac tcattttctt tccaaacatc tctatagatg
    38701 tatcaggatt tgatacatca tgtattactc tcatatttac ttttactttt tctaaactct
    38761 tgctattttc tataaaagaa gaaccacttc ctttacctcc catgccaggc acttcacctg
    38821 cacaagcaac cccattacaa accttacaaa ctttacaact tccatttaaa ttttctctag
    38881 cactttttaa taattcatta tattccatct ttaatccccc attaactata gtaatttata
    38941 ttatatacat tatatcatat tatatttaca gtatattttt caaaaaactt tttctgtgga
    39001 taggagttat gccatatttt tcaatagctt catagtgttc tttagttcca tatcctttgt
    39061 gagatttaaa cccatattct gggtatactc tatcatattg gtacattata ctatccctag
    39121 taactttagc aagtatactt gctgctgcta ttgatataga ttttgaatct cctttcacaa
    39181 ttggattttg agatatgtca atacctggta ttgttgctgc atcaactaat aaataatccg
    39241 gtgctttttt taaacaattt atagcctttt tcattgccat atatgtagca tttaatatat
    39301 taaattcatc tatttcttca ttgtttacta tacctattcc ataatctagt gcttcttctt
    39361 ttattacttc aaaaagttca tctctttttg cctcactcag tttcttagag tcatttacac
    39421 cttctatttt ggtatctttt ttaaatacta caacagaagc tacaacaggt ccagcaagtg
    39481 gtcctcttcc cgcctcatca attcctccaa tatataaata acctttatca tagccttcgt
    39541 tctcaaatat atttatagtt tccaatcttt cttcttcttt tctaatatta tccagctttt
    39601 ttgccagttt tatagctaga ccttgtacag attttctttc atcaactctt aacagctcta
    39661 tatattccat atatttttct acttctaaag tctctattat ttctttaatc tccctcacac
    39721 ttttatcctg cataccattc cctcatcttt cgtttttaaa aatttaattt ttaaatatat
    39781 taaaattttt taattagagt ttaattgcat ccactatagc cacattttaa acatatacta
    39841 catccacctg tatgtgcaat tccttcactt ccacactcag ggcacacaaa tttttcatct
    39901 ccttcaaaat ttttatttat tatttctttg gctttttcat ctttattatc tttttctttt
    39961 ttattatttt tataatattc ttttttacta ttttcttttt tatcttcttt attattttct
    40021 tccttttttt catttattaa aattccactc cttttacatc catctctaaa tattgttact
    40081 cctttaagac cagcctccca tgccttaata tatatattga aaacatcttc aactgtagtt
    40141 tcaaaaggta tatttattgt agatgatata gaagcatcaa tatacttttg ccatactttt
    40201 tgcatgttta ttctttcttc atatcctata ttcatagcag taacaaaaaa atctggtaaa
    40261 cattcttcat ctgtaatacc tttcttgtcc atatactctt taacaattgg agtatatact
    40321 ttataataca catcctcatc atgcaagctt tcagtttttc ttatatatga aagattaaat
    40381 ataggttcta ttccaccact gatacctatc attgtagata tggaacctgt aggaggtatg
    40441 gttaaaagtt gtgaatttct aagcccatac tttttaacca tttccttagt gtcttcattt
    40501 agattttcta taaaaaactt agatttagaa atattttcat atttatactc actaaatgtt
    40561 ccatattctt tagcaattaa tgctgattgc ttcacagctt catttaacat agtcttacca
    40621 attaaatcac atagttctaa agattcatca gaaccatatc ttattcccat ttttataagc
    40681 atatcagcta tacccattac acctaaacct atctgtctat acttatgtac actatctctt
    40741 tgttcttgta atggatgcaa gttcaatccc tcatctaaga catcatttaa agctactaca
    40801 gcttctctaa cgcaagattt taatttatta atatcaaaag tagcatgttc accaaatggt
    40861 tgtattataa actctgacaa gtttattgag ccaagtagac aacttcctcc acttggaagt
    40921 ggttcttctg cacaaggatt tactcctgaa aagcaaaagt tcttatcttc actcataaaa
    40981 ttatatgttt ttattttatc ccaaaacaat atacctggtt ctgcataatc ccagttattt
    41041 ttcacaaatt tattaaataa atcataagca tttactatct taactatttt ttctccagta
    41101 gtttcaactt caaaagtaca attatataac tttttttctc ttacagcttg cataaattca
    41161 tctgttactc ttacagaaat atttgcttta gtaaccttct ccaaatctgt ttttatatct
    41221 ataaagtctt ctatctctgg atgatttaca tccatagaaa tcataagagc tcctcttctc
    41281 cctctttgac caattaagcc agttgtcata ctgtaaagtt ccataaaaga gactgctcca
    41341 gtcgtatgtt ttgcagcatt gttaactttc gctccttttg gtcttagctt tgaaatatca
    41401 attccaactc ctccaccata actaaaagtt ctagcaagtt tttttgcagt atcaaatata
    41461 tcttctatgc tatcttttgg tggttctatt acataacaat tagaatatgt tacttttttt
    41521 ccctctttct gtaatcctct atttgctaaa attcttccag caaatagaaa ttttttttgt
    41581 cttattagtt ttgatattct tgaactatta tttgaaattc tctttatcca ttcatcaaaa
    41641 ctctcaccat tatgtctata cttgttcttc catattgatt tttgtaattc atcaaactcc
    41701 caagctttag tccttatttc agagcgtctt tctctatata atatgtagtg ttttgctata
    41761 tcttttctat ttgattccat aagtagtact tcaactatat cttgtatttc ttctacggat
    41821 aagcattttt ccatagaatt atagtcatta gctatttttc ttgatatacc atatgccaac
    41881 tctctatcta ctccaccttc actatttata ctagctttat agacagcatc ttcaatctta
    41941 cttttactaa aaagttcttt tgtaccatct ctttttatta tgtatttcat ttttaaacct
    42001 ccaataaatt agtattaaat taatacacac attaactata actctaaaca aactttttat
    42061 atatttgtat attttcatat taattatcta acataatata tattatac
//
LOCUS       DAMJWC010000032        41624 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMJWC010000032 DAMJWC010000000
VERSION     DAMJWC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41624
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.032"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            144..2237
                     /locus_tag="PC503_001949"
     CDS             144..2237
                     /locus_tag="PC503_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2527921.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     gene            complement(3290..3574)
                     /locus_tag="PC503_001950"
     CDS             complement(3290..3574)
                     /locus_tag="PC503_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527922.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     gene            3781..4599
                     /locus_tag="PC503_001951"
     CDS             3781..4599
                     /locus_tag="PC503_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2527923.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(4732..6852)
                     /gene="feoB"
                     /locus_tag="PC503_001952"
     CDS             complement(4732..6852)
                     /gene="feoB"
                     /locus_tag="PC503_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2527924.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKNSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(6878..7105)
                     /locus_tag="PC503_001953"
     CDS             complement(6878..7105)
                     /locus_tag="PC503_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2527925.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            complement(7432..7872)
                     /locus_tag="PC503_001954"
     CDS             complement(7432..7872)
                     /locus_tag="PC503_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527926.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            8024..9013
                     /locus_tag="PC503_001955"
     CDS             8024..9013
                     /locus_tag="PC503_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF2527927.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGLIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISLYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     misc_binding    9165..9417
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9490..10698
                     /locus_tag="PC503_001956"
     CDS             9490..10698
                     /locus_tag="PC503_001956"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF2527928.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     gene            complement(10759..11640)
                     /locus_tag="PC503_001957"
     CDS             complement(10759..11640)
                     /locus_tag="PC503_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2527929.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            12026..12970
                     /locus_tag="PC503_001958"
     CDS             12026..12970
                     /locus_tag="PC503_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2527930.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            13193..13738
                     /locus_tag="PC503_001959"
     CDS             13193..13738
                     /locus_tag="PC503_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2527931.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            13829..14977
                     /locus_tag="PC503_001960"
     CDS             13829..14977
                     /locus_tag="PC503_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2527932.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            15030..16295
                     /locus_tag="PC503_001961"
     CDS             15030..16295
                     /locus_tag="PC503_001961"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF2527933.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(16581..17813)
                     /locus_tag="PC503_001962"
     CDS             complement(16581..17813)
                     /locus_tag="PC503_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527934.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(17816..18490)
                     /locus_tag="PC503_001963"
     CDS             complement(17816..18490)
                     /locus_tag="PC503_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527935.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            complement(18498..19727)
                     /locus_tag="PC503_001964"
     CDS             complement(18498..19727)
                     /locus_tag="PC503_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2527936.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALSSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            complement(19839..20843)
                     /locus_tag="PC503_001965"
     CDS             complement(19839..20843)
                     /locus_tag="PC503_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2527937.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            complement(20867..21541)
                     /locus_tag="PC503_001966"
     CDS             complement(20867..21541)
                     /locus_tag="PC503_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2527938.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            21829..22596
                     /locus_tag="PC503_001967"
     CDS             21829..22596
                     /locus_tag="PC503_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527939.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            22583..24520
                     /locus_tag="PC503_001968"
     CDS             22583..24520
                     /locus_tag="PC503_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527940.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEVEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVAKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            24745..26358
                     /gene="ggt"
                     /locus_tag="PC503_001969"
     CDS             24745..26358
                     /gene="ggt"
                     /locus_tag="PC503_001969"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF2527941.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(26491..27342)
                     /locus_tag="PC503_001970"
     CDS             complement(26491..27342)
                     /locus_tag="PC503_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF2527942.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            27968..28861
                     /locus_tag="PC503_001971"
     CDS             27968..28861
                     /locus_tag="PC503_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF2527943.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            28861..30255
                     /gene="gltA"
                     /locus_tag="PC503_001972"
     CDS             28861..30255
                     /gene="gltA"
                     /locus_tag="PC503_001972"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF2527944.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            30621..32840
                     /locus_tag="PC503_001973"
     CDS             30621..32840
                     /locus_tag="PC503_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2527945.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            32987..33733
                     /locus_tag="PC503_001974"
     CDS             32987..33733
                     /locus_tag="PC503_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2527946.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            33733..35613
                     /locus_tag="PC503_001975"
     CDS             33733..35613
                     /locus_tag="PC503_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2527947.1"
                     /translation="MDFRKFAYNNIVKNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGVII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            35732..37123
                     /locus_tag="PC503_001976"
     CDS             35732..37123
                     /locus_tag="PC503_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2527948.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            37230..38270
                     /locus_tag="PC503_001977"
     CDS             37230..38270
                     /locus_tag="PC503_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2527949.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            38759..39412
                     /locus_tag="PC503_001978"
     CDS             38759..39412
                     /locus_tag="PC503_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2527950.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKAAEKIDGIIDGMKF"
     gene            39488..39697
                     /locus_tag="PC503_001979"
     CDS             39488..39697
                     /locus_tag="PC503_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527951.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(39837..40403)
                     /locus_tag="PC503_001980"
     CDS             complement(39837..40403)
                     /locus_tag="PC503_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF2527952.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            40564..41217
                     /locus_tag="PC503_001981"
     CDS             40564..41217
                     /locus_tag="PC503_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF2527953.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGFSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(41375..41551)
                     /locus_tag="PC503_001982"
     CDS             complement(41375..41551)
                     /locus_tag="PC503_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527954.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT        15802 a         4766 c         6561 g        14495 t
ORIGIN      
        1 tataatttaa aatatgaagt aataaacttt ctaattaaat taaggtattt agtgtatatg
       61 tataagttat aagtaaatct tctaaaaaga ataattttaa caatgttgtt ataaagagca
      121 gtaactatgg aggagataag tatatgaaca aacataattt tgaagttata ttaaatcaac
      181 tacagattaa tatatatgtt acaaatattc atactaatga aattattttt atgaacaaaa
      241 aaatgaaaga agaatataat attttagatc cagaaggaaa agtttgttgg caagtattat
      301 atcctgaaaa aaattctact tgtagttttt gtaaagtttt agaattatta aagaatgata
      361 aaaaaggagt attaataaag tggtatgaaa aatgtaataa gttaaatcgt gtttttgaaa
      421 attatgatag tttaattaca tggcaagatg gcacagttgt tcatatgcat caatcaatag
      481 atattgcaaa ctcaacaagc ttaaataaac caattaagat taatgaattt catgaaatat
      541 caaataataa agaagaaaaa ggagttttta atttttcaag agacaatttt gattataatt
      601 ctacattgct ttacgatgct ttgattagag gtacagatga atatatatac atttgcaata
      661 tgaaaacagg cgtatttcga tattcaccat cacaagttga attatttgac ttaccaggag
      721 aaattgttaa aaatccgctt gtttactgga aaaaaattgt acatccagaa gactggaatc
      781 gtttttataa gtcaaacact gaaataggta aaaaccagat ggattatcat acagtggaat
      841 ttagggctaa aaatcgtagt ggagaatata tatggttaag atgtagaggt caactaatgc
      901 gtgatgaatt tggagagcca agtatttttg caggaataat gacgcaatta ggtaaacaaa
      961 ataagattga ttcattgaca cagttactga attatcatga atttatgagt gtatttgaag
     1021 ataaaatttc aaatcctatg attgaaaaat tatgcatagt attattagat attgacgatt
     1081 ttaaaaatgt taatgagatg tatgataggg attttggaga taatataata aaaacactag
     1141 cacagtctgt acaatctatt ttaccagata atgctgaact ttataaactt gatggggacg
     1201 aaatgggcat tcttgttgat aatgttgaag aaaatgaaat tctaactcta tataatcaaa
     1261 tacagaatat gattatacac cttcaactat ggagaaaata tggattaaat ataacaattt
     1321 ctgctggttg tgtaatatat ccaaaacatg gagatacagt aaaagaactt tataagtgtg
     1381 ctagttactc tttacaatat gcgaaagagc atggtaaaaa caggcttgtt tttttctccc
     1441 aagaaatatt aaaaaataaa atgtattcat tagaaatgat gcgggattta aaggcatcaa
     1501 ttaatgatga ttttaggggg tttagtcttc gattccagcc acaagtagat acagaaagtc
     1561 ataaaataat aggtgtagaa gttcttttaa ggtggactaa tgacaaatgc aaagcaattt
     1621 ctcctttgga atttattcca atattagaag aaaatgatat gataaatatt gtaggggctt
     1681 gggtgcttcg aatggcatta cgtactttta ggaaatggat tgattactat ccttttttta
     1741 aagtgagtgt aaacgtttca gctgttcaaa tattagaaga cacatttatt gaagatatag
     1801 taaaaattat agatgatgaa aattttcctt atcaaaatct tgttttagaa ttgacagaaa
     1861 gtcatacagt acaaaatatg agtattttac agtttaaatt taaggcttta caagatttag
     1921 gaatttatat tgctatggat gattttggta ctggatactc gtctctagaa gttttaaaat
     1981 tttctccaat agatatagtg aaaattgata gagtatttgt taaagatata ttaaagagta
     2041 agtttgatgc tacatttata cattttattg ttgcaatttg tcatgatgta ggaataaaag
     2101 tatgtttaga aggtgtagaa acacaagaag agtatgattt agttaaacaa ataaagccag
     2161 attacataca aggatattta tttggaaaac cgcagacagc aacagaaatc tttgaccttt
     2221 taaagctaga taattaattc taatttatca ataatatcac tgaaaagctt taaaatcaaa
     2281 aatacattaa attattatat tgaagatata tcaattataa attgcaatat aagaaaatag
     2341 catttcaatg gatgttaaat tgggaatagt atatgattaa agtattttaa aaagggataa
     2401 ccataataaa aatagatatc tatttttaga ttaaaaataa tatatcataa ataaaataat
     2461 aagaggtaga tacagtttta agggaataca aaagttttta attaaactat gcttgttcag
     2521 atagatattt atttaagaaa aaagactatt aaaagcaata tacaagaatg atatattaga
     2581 ttgattaaac aagcataaat attatgtaaa aaactttaag ttatagaatt taaatctaat
     2641 gtagatagat tacgtttttt tgcttttatt atggtataaa ttggtatcaa tattcaaaag
     2701 taatatattt atgatataat aaaattatag gaattttgca gtgagcgata tttgtgaaaa
     2761 aatttggcgt aacagttgaa atataaggcg ttgagagtgc atgataagcg ttatcaattg
     2821 cactattgct cgttcactgc aaatttagga gagttgtata cgtgtaagtg ttgaaaatac
     2881 taagtttatt ttggtgtttt atattaacta tatggaatgt aaatgcatgt taaagtggct
     2941 aattggaact atgattacaa cgttttatat taactatatg gaatgtaaat atttgatttt
     3001 aatggtacgt tttcgctttc tctaaggttt tatattaact atatggaatg taaatctatc
     3061 ttttgttgct ttacataaat ttatattact tatgttttat attaactata cagaatgtaa
     3121 gttttcataa ttttctttta atgtgttatc ttatgattat ctagttacat tagcatacaa
     3181 aaatataata aaattacact atattataaa aacaaaaagg tagtatagaa atcctattac
     3241 ctttttatta ttaattttat cagtgtttta ttataaatag cttacataat tacacatttt
     3301 ttctgattaa ataatatgat gctattgtta taatagatac taatgctaat gatgttattg
     3361 cagtatctaa tcttcttatt aataaactca tttctatata ttcaagttct attaaatact
     3421 gataaaatat ttctagttta acagcttttt ctctatctat atttccgtac tttaactcta
     3481 atttatctaa agatttttta ttacaataat taactttatg tttaattaaa tatcttattg
     3541 tagcacctat tacaattttc actctaacaa gtataaatat aatattccat ccaaaagtta
     3601 agaggggata tcttttttat gatgggaaag ggtaaaatat ttataactga catctaactg
     3661 atatttaagc tttaaaatca aaaccatatt gattttctaa aataataact acttgattta
     3721 gtaaataata aagaatatag taactatata gacaacaaaa agaaaaggag tgtataaccc
     3781 ttggaaaaac agtattttac aacaggtgaa tttgctaaat tgtgtggtat atctaagcag
     3841 acattaattt tctatgacaa aataggtatt ttttctcctg aatataaaga taaaaataat
     3901 tatagatatt actcagttta tcaatatgat acacttgata tattacaatc attaagagaa
     3961 ataggaatga gtttagagga aataaaagag tatatacaaa atagaactcc ccagctttgt
     4021 gtgaaaatgc ttaaagaaga agaaaaaaag ataagagaaa aaataaaaaa actaagaaag
     4081 ataagttcta agatgcaaaa tagaataaat ataacagttg aaggaatttc taaaatgaat
     4141 agtgaagaaa tttatatatc caaaaagttt gaagaatatt tagttctatc aagcgatttg
     4201 agtaatatga gtaatagtga ttttatgatg gaattaatag attttaccaa ttattgtaaa
     4261 tcgaaaaatt tgtatcaagg atatgagttg ggagtaatag taagtaatga aaatataaaa
     4321 aatggggact atttaagtat atcaagtttt tatttgaaga tagataaaaa aataaaggat
     4381 aaaaagctat atgtaaagcc agaaggaatg tatgcttgca taaaacatat tggaaaatat
     4441 gaggattcat ataaatctta cgaaaaattg aaaaaatata tatatgaaaa tgaatataaa
     4501 attgttggaa attcgtatga ggagagtata cttgactttt tttgtgaaag taatgaagat
     4561 aattatatga ctgaaatttc aatccaagta tccagataag aattaaaata gagatatatt
     4621 caaatgttaa gtaattttac ttatcattga atatatctct atgctttata ataaagtata
     4681 taaattttta aatggtttct ctaatatatg tctactgtca gttaatacta attatataaa
     4741 taaattgtaa actgtagttg ttaaaaaaca aacaacaaaa gcaagtatag taggcattaa
     4801 gaatcctaag gcagtccatt ttaaactacc agtttctttt tttattgtta aaagtgttgt
     4861 tgcacaaggc caatgcagta aactgaacag cataacattt aaagctgtca aataagtcca
     4921 tccatgttct ctaagaactt gacctaaagc actaaagcta tctaattcta tcatagaacc
     4981 agttgctagg taagccatta aaagtatagg tacaactatc tcatttgctg ggaatccaag
     5041 aataaaagca agtaatataa aaccatcaag accaattaat ttagctaaag ggtctaaaaa
     5101 gtttgcaaca tgtgataata tacttaaatc tcctatatat atatttgcaa atatccaagt
     5161 tatgacacca gcaggtatgg ctaccattac agcccttcct aaaacaaata ttgttctatc
     5221 tattatagag gtatataaag ttcttcctat ttgaggaact ctataaggag gaagttctaa
     5281 tgtaaatgta gacggaactc cttttaatag cgtcttagaa agagtgtaag aaaccaacaa
     5341 tgttattata acacctagaa ttatcagtaa agttatgcaa agtgcagttg ctacgcttga
     5401 tacgaaagag ttggttataa ctgagctaaa aaatattgta gatatagcta tcaaagtagg
     5461 aaaacgacca ttacaaggaa caaagttgtt tgtaagtata gctataagtc tttcccttgg
     5521 agagtcaatt atcctacaac caataactcc agctgcatta catccaaatc ccatacacat
     5581 agtcaaacac tgttttccat gtgcacaagc ttttttaaat aggtggtcta agttaaatgc
     5641 aactcttggc aaatatccaa aatcctcaag tagggtaaat aatggaaaaa atattgccat
     5701 aggaggtagc attacagaga ttacccatgc taatgttctg tataatccta aaaccaacat
     5761 atcatttaac catgatggac aattaatact atttaatata cccgaaatac ttggctcaaa
     5821 tccgagtaat aaattagata ataaagtgga tggatagtta gctccttcta tagtaatcca
     5881 caatatagta cctaataata agagcattat tggaagccca aatattttag atgttaatat
     5941 tttatctact ttttcttctc tatcagttga ttttttagca acattagaac aacactcatc
     6001 actcagtttt ttagcataat catagttgat tttagtaaac tcatctctta ttttctgttt
     6061 atttatattg tctggaatct ttttctttac ttcattaata gcatctatag aatttttgtc
     6121 tatataatta ctcatagatt caaatatact ttcatcgcca tcaataagtc taagtcccaa
     6181 ccatctagaa tttatacctg gtataatatt atccaattct ggttgaattg attttaccac
     6241 attctctata ttttcattgt atctaacagg tttattattt aatttatatt tgtcaaaaga
     6301 tacatcattt aaagtatcca atagttcatc cataccagag ccatttcttg cagcagttaa
     6361 aataactgga ataccaagag aatcctctaa aagtttttta tcaatagtaa tgcctttttt
     6421 tctagcttca tctattaaat taatacacaa aataacttta tctgtaagtt ccatcacttg
     6481 aaatactaaa tttaaatttc tttcaagaca tgtagcatca catactacta ttactgcatc
     6541 tggattacca aaacatataa aatcacgagc tacaatttct tcttgtgata aggcaaataa
     6601 agaatatgtt cctggtaaat ctattaatgc atattcggta tttttatatt taaaattacc
     6661 acgagctgta gctacagttt ttcctggcca gtttccagta tgctgtctaa gtcctgtaag
     6721 atgattaaat acagtacttt tacctgtatt tggattgcca gccaatgcaa ttacaaactg
     6781 gtcttcctta ttgtctatat caaacatgtc ttttaaagaa ctcattttag ttgagttatg
     6841 tgtcaacccc atattaatat cctcctgcta gaaattttta aatgtcagaa actaatatta
     6901 agctactttc ttcttgtcgt agagctatct tgctacctct gattttatag acagttaaat
     6961 tattttttgg accttttcta actacatcta taacagctcc tctagtaaga ccaagcgcta
     7021 acattctttc tcttaaatta ccactagata atatatcttc aactttgaca gtttttttca
     7081 cttgaatatc gttaaggttt ttcataatag cacctccatg cttgaaattt agcctgggct
     7141 aatcttctta ttttaaacta tgcattatat tattaccttg ttacttttac aaaaaaaaga
     7201 taggcaagat gcctatcata caaagttggg tataattctt acttttgggg aaagtagaat
     7261 atagaataaa aattaacact ttgaatccat ataattattg aattttgata ataaaaaagt
     7321 cagaaagcaa aagccttctg actctatgta aggtattttc aaatacctaa atatcaattc
     7381 aatatttaat ttatacttaa attatatatt aacaatatta gcttgtcaac actataatct
     7441 cattttaata tgttcaatac ctgcttcgtc gtatacttct gagatttctt taaaaccaca
     7501 agataagtaa aggttcttta tataagtttg tgctgataag gttatattat tttcgtgtaa
     7561 gttaactttt ataaaatcta tagcacaatc catcatttgt tttgctaatc cttttcttct
     7621 atgactagaa agaactaaaa ctctaccaat ggaaacatca ttataagagc tgtattcttt
     7681 aggaattatt ctagcgtaag cacaaatcaa tccattttct tttaaaaata tgtgataaga
     7741 gtttttatct atatcatcat aatcgtttaa tgaaaatatc ttctgttcac aagcaaatac
     7801 ctcatatctt gattttgcta tttcataaaa ttcatctaaa ctcaaatcat taaagtgttt
     7861 aattttaaac atagtaatta cctcctagca tcttaaaaaa ctgaatatta agatacatta
     7921 taccattttt aacataaata cctttattaa aatttatatt tattaaaaat atttttaaaa
     7981 agtgatatac tatattaaaa acaaaacttt agttagaaaa tttatgattt atggaggcag
     8041 tgttttgaat actactaaaa aattaactga agcagcttta ttgtcatctt tattcatagt
     8101 agtaacaatt atagctgtga gtactggatt tggatatgct atttacttag attttatagt
     8161 gccagtattt ttttgtataa tctgcttgaa atgtgattta aagtatacca ttttatctgg
     8221 aattacttcg cttttaataa tttctctggt acttggaaat ctaggaactg ctatttgggc
     8281 aagtcagagt gtattacttg gtataatgtg tggctatcta ataaataagc ctacaatggt
     8341 tatggatgat ttagtatatg gttcagtatt tgggcttatt gtaatggttt ttattgatat
     8401 atatgcttca acattaatag gttatagttt tatgaaagaa tttcaaggat atagcaaatg
     8461 gatttatttt aatgggtata caaattttat ttattattta atgatagcat tgtttccttt
     8521 tggtatggtg ttttgcatat atttattaag tttaatttta gggaataaat tgcatatttt
     8581 agattctaat tctctaaaaa aatttttaat atttaagaat tttagaagtt taaaccaatt
     8641 tttatgttgc tcaaaaaaag ctttttacat atgtgtttct tatctagcca tttttgaagt
     8701 tctaaaactg ttgaatgtta aagttgattc tgtttattta aaaacaatct ttatatcaat
     8761 aacctatata agtctctatt ttatcattag agactcatgt atgtcactac aaaactttat
     8821 aatagctaag tttagaaaat tattatatgc tagaatttta tttttgataa taattttatt
     8881 gctgtttttt atatttgatg taacagttat tggtttaata attataaacg catttttaaa
     8941 taagaaaata aatataagat tgagtcagag taatatagtc aataaacaaa taaatctttt
     9001 gattgaaaaa taaattttgg gtattggtaa aaaatataaa aaagtagtat aatgtaaaaa
     9061 aacatgtata taataataaa aaaggttgac aaaatataaa aataataata tattatgagt
     9121 aagttaagaa aaatttcttg taattgatga aataatctga atatataaat gctatgaaga
     9181 gaagaagtag ggctagattt tatttaacag agagttccag tttggtgaaa tggaataaat
     9241 tgatttagtt tgaatacatc tcagagcact atctctgaaa gataacaacc attaagagat
     9301 atcggattag tacacgttat agtacacgag tatatgtaat tgtactctaa gagattaata
     9361 tcgtgagata ttgatgaact aaggtggtaa cacgtaagca atgctttcgt ccttttaaga
     9421 ggatgaaagc tttttttatt ataaaaataa aaattataga ttatataaat attttaggag
     9481 gaatgaaaaa tgaaatcgat agacgagcaa atgcgaataa ttatgaaagg tgtagatgat
     9541 ttaatagatg agaaagagtt aagggaaaag cttattaaat cagaaaaaga aggaaagcct
     9601 atgatagtaa aattgggtct agacccaagt gctccagata tacatttagg gcatacagta
     9661 gttcttagaa agatgaaaca attacaagat ttaggtcatc aaatagtaat aataattgga
     9721 gattttacag gaaaaattgg agacccaact ggaaaatcta aagctagaaa agctttaaca
     9781 acagagcaag ttcttgcaaa tgcaaaaact tatgaagaac aaattttcaa agttttagat
     9841 aaagaaaaaa ctattgtaag atttaatagc gagtggttag ctaagttaaa ttttgaagat
     9901 gtaataaaat tagcagcaac tattactgtt gcgagaatgt tagaaagaga agattttaaa
     9961 aagagatatg aaggacaaat gccaatatca gtacatgagt tcttctaccc attaatgcaa
    10021 gcatatgact ctatagcatt agaagctgat atagaacttg gtggaactga ccaaagattc
    10081 aatttactaa tgggaagatc attacaaaga gaatttggta tggagtctca aatagtaata
    10141 atgatgcctt taatagaagg attagatggt aaagaaaaaa tgagtaagag tttaggtaac
    10201 tatattggaa tagatgaaga agcgggaata atgtaccaaa aatctatgga aattcctgat
    10261 gaacttataa ttaaatacta caatttagtg acagatgttc atcctgatga agttaataaa
    10321 atagaatcac agttgaaaga gggttcagta aatccaagag atataaagat gaacttagca
    10381 agagaaatag taacattata ccatggagaa gaatctgcta aagaagctga agaaagattt
    10441 aaatctgtat tccaaaaagg tcaaatacct gaagatatac aaacaattca agttaaggaa
    10501 gatggatttg acttaatcga agtactagtt tctaatgaga ttgttaagag taagagtgaa
    10561 gttagaagat tagcttctca aggtggagta aaggtaaatg gtgaaaaagt agaggattta
    10621 agcactattg taaaagagag tgaattagtt gttcaaatag gaaagaaaaa atttgtaaaa
    10681 atcgagctag taaaatagag taaagtaaaa gcaagtctat tgagtataaa atgtacattc
    10741 aataaacttg cttttttatt atattaaaat tttaaattga taaccattgt ctttaaaata
    10801 tgttataatt tggtccaatg catttactgt ttcttgtttt ccataagtat catgcattaa
    10861 aagaacaacc atttctttgc cttcagaaga tttctttgca tgttcaaata attcttgtgc
    10921 atttttcttt ttaccttctg catcagcatt taaagcgttc caatcaattg atgccatgtt
    10981 tttctctttt aagtagtttc ctagaggttc catatttttc catgacatat acccgcctgg
    11041 gcatctaact acatttgagg aaaaattctt tcctaagact tttttcatag cttcatcagt
    11101 tttgttaagt tcatttacga atgtatcgag atttaggctt ctgttaggat atagtttttt
    11161 atagtcatga gtataagagt gatgggctat tgcatttcct tcgtcaaatg ttctttttaa
    11221 aatttcatta gctccttttc tttcaagaga atcaccctta ataaagaaag ttcctctaac
    11281 accatgtctt ttcaagatat ctagaacttg tggagtatta gtagtagatg gtccatcatc
    11341 aaatgtaaga aagactatct tttctccatt gtttgaatag tcgtatttgt taagtttgtc
    11401 ccaaactatt tttgcgtcat atccatattc ttttacagct tctttttttg caccaataat
    11461 aggttcattt ttttcttttt caattctttc tttttctaat ctttcagctt taagtctttc
    11521 ttgagtttct ttcatttctt tttttctaga catgtccgcc catgccatag aaaaaatacc
    11581 aataactatt acaacaagta tagtaagtgt aacagttttc ttttttcttt tttttaccat
    11641 aattacagca ttcccccttt tgtcgaattg tatcaaaaat atattataat tatatcgaag
    11701 aaagtagaaa aagtaaaccg acaaagttgt aactaagata actaaagtgt aacttatatg
    11761 acattatttg cataatatta aagtatcata tatattaaaa atatctataa aaaaatttag
    11821 tataggtaaa aaaatataaa aaatataaaa atttattaaa aaggtgttta caaaaaatga
    11881 ttaatatatt actgttaaat agtggatata aatttgagct caaaatgtat gtaaatttag
    11941 atttaaaata ctgaaaaaat ttactatatt aatttatagt aatgcttata gaaaaactct
    12001 cttgctgttt agggggttta taattttgca aaaaaataaa aaggaggggg ctttattgaa
    12061 aaaatacttt ggagaaatag gactaatatt tatagcaatt atatggggaa gtggctttgt
    12121 agcaacccaa tttgcattag acggtgggct tacacctcta caaatcataa ctttaagatt
    12181 tttcttggca gctataatta tgaatttact gttttttaaa cagattcgtg ctaatatggg
    12241 taaaaaatta ttaaaagcag gagggatttt aggaatattt ttatttctag cattcacagt
    12301 acaaactatt ggacttatgt acactacacc atctaaaaat gcgtttataa cagcagctaa
    12361 tgttgtaata gttccattca taggatttat actttataga agaaaacttg ataaaatagg
    12421 aataataagt agtttggtag ctcttatagg aattgggata ctttctttag aagctgattt
    12481 ctctattaat tttggagatt ttctaacact tatatgttca ttcggatttg catttcatat
    12541 attctttaca agtgagtttg caaaagataa caacccaatg gcattgacag ctattcaatt
    12601 tacagtagcg tttttaatgt ctgttgtagt tcaaacattt gcaggtcaat taaagatgga
    12661 agctgaatta tctggttaca tgggaactat gtatctagct gtatttagta ctacaattgg
    12721 atttttattt cagactatat gtcaaaaaag agttgatgga actagaacag ctataatatt
    12781 atccacagag gctgtatttg gtacaatatt ttctataata attttaaagg agcttattac
    12841 agcaaaattg gttattggta gtatcttgat atttgttgca atcataactg cagaaactaa
    12901 attatctttt ttaaagagca aaaaagtgaa acttaaagat tcagaggagt cttcattaga
    12961 aagtatttaa tatgacaact atttcctaat taatcaaata aattatgtat tatgtagaaa
    13021 tttgacatca aaacttggtt gatactggtg tttcaaagtg ataaaattaa ttaggaaata
    13081 aattttattt ttagtgttta agctataaag tctggggtat atatattctt gtagcaagtt
    13141 attaaactta aaaataaaaa tttaattata taaaattggg aggaaattaa ttatgaaaaa
    13201 atttgtttgt acagtatgtg gatatataca tgaaggagat gctgcaccag cacaatgtcc
    13261 agtatgtaaa gttggagctg ataaatttga agaaatgaaa ggcgaaatgg tttgggctga
    13321 tgaacataga ataggagtag ctcaaggtgt agatgcagaa ataatcgaag gattaagagc
    13381 caactttact ggtgagtgta cagaagtagg aatgtattta gcaatgagta gacaagctga
    13441 tagagaaggt tatccagaag tagctgaagc gtataagaga atagcttttg aagaggctga
    13501 acatgctgct aaatttgcag aacttcttgg agaagttgta gttgcagata caaaagaaaa
    13561 cttaagagtt agagttgatg ctgagtatgg tgcaactgat ggaaaattaa aattagctaa
    13621 gagagctaaa gaattaggat tagatgctat acatgataca gtacatgaaa tgtgtaaaga
    13681 cgaagctaga catggtaaag cattcttagg attattaaac agacattttg gaaaataata
    13741 attaaaacat agattaaaag gagaaacttt ggtttctcct tttttaaatt atacaaataa
    13801 actgttgtga tagaaggatg gagataatat gaagtcggta tctgttagga gttgtaaaac
    13861 ttacaattat gaagaagtaa agttatctat tgaaaaaaat ttagaggata ttggtggtat
    13921 agataagttt gttaaaaaag gaagcaaagt acttataaaa ccaaatttat taatgaaaaa
    13981 aaagcctgaa gaagctacaa ctacacatcc tatggttgta aaagttgtat gtgaaaaact
    14041 tttagagtta aattgtgata ttacaatagc agatagccct ggtggtccat ataatcaaag
    14101 ttctcttaag agcatttata aggcatctgg aattgaagaa gtagcaaatg aactgggcat
    14161 taagttaaat tatgatgttt cagatgttaa gatacatagt gaaaaagcac atgttctaaa
    14221 atatatggat attattaaac caatagtaga ttcagattat ataataaatc tttgtaaatt
    14281 aaagactcat ataatggcaa cttttactgg tggtacaaaa aacttatatg gatgcatagc
    14341 tggattgaaa aaagcagaga tacattatag atttcctaca gaagagttgt tttgcgaaaa
    14401 tgtactttta gatatttgtg attatataaa accaacattg acaattatgg atggtatagt
    14461 aggtatggaa ggtgatggac cttcagctgg tactactcga gaaataggcg ttttattagc
    14521 atcacaaaat ccatatgcta tagatgttgt tgcatgtaag attataagtt tacttccaaa
    14581 tagagttgct acaattagag gtgctattaa gagaggatat atacaagaag atttttcaga
    14641 tattgaaatt ttaggtgaag atataaaaga tttaattata aaaaattaca agattccaaa
    14701 tgtaagtaag gatttaagat tgttttctgt aaagctacca aaatttttaa atgaacctat
    14761 ttcaaagctt ataacaccaa agcctgtggt aagatttcaa gattgcataa aatgtggaaa
    14821 atgcaaggaa gcttgtcctg catccactat agagataggg actaagggtg ctattataga
    14881 cttaagtaaa tgtataagat gttactgttg ccatgaactt tgtcctaaaa aggctattga
    14941 tgtcaaacgt aattttgtat ttaagtatgt aaaataatgt ataatattat atgagtctat
    15001 ataaattaaa aatataaagg agaaataata tgattttaat taaaaatggt agagtaatag
    15061 accctaaaag tcaaagagat gagaatattg acttaattat aaaagaaaat aaaatttata
    15121 aaataggcaa gtttgatgaa agtgatgaat atgaaaaaat aatagatgct agtggtaatg
    15181 tagttgctcc aggtttagtg gatgtacatg tacactttag agaccctggg tttacatata
    15241 aagaagatat agaaagtgga gctaaatctg ctgctagagg tggatttaca actgttatat
    15301 gtatggcaaa tactaatcct attgtagata atgaagatac ttttaattat gttaaagaaa
    15361 agtcaaaaaa tgcatgtata aatgttttac aagcagcagc tataactaaa ggttttgaag
    15421 gtaaagagtt agttgatatg gaagctctta aaaaagctgg tgtaccaggg tttactgatg
    15481 atggattacc tttaatggat agcaatctaa ttatggaggc aatgattaag gcaaaagagt
    15541 tggatgtacc acttagtttt catgaagaag acccttcttt agttggaaat ccaggtgtaa
    15601 atgcaggaaa ggtagcttca gaacttggat taaaaggtgc atcaagtgta gcagaagatg
    15661 ttatggtagc cagagattgt atgttggcac taaagactgg tgctaaagtt gatatacaac
    15721 atataagttc aggtgtatct gttgatatgg ttagatttgc aaaatactta ggtgcaaatg
    15781 tagttgcaga agcttcacca catcacttta cattgactga ggaagatgta ttggagtttg
    15841 gaacaaatgc aaaaatgaat ccacctctaa gaagtaaatg ggacagagat aagattatag
    15901 agggattaaa tgatggtact attgaaataa tagcaacgga ccatgcacct catagtaaag
    15961 aagaaaaaga tagagagttt ataaaagctc caagtggaat tattgggctt gaaacttctt
    16021 tagctcttgg aataacaaat ttggtgcata aaaatcatct tagtatgatg cagttaatag
    16081 aaaaaatgtc tataaatcct gcaaagttgt acaatttaaa tattggattt atagaagaag
    16141 gggctgtagc agacattgtt atattcaatc cagaagaaga atggacagtt gaaagctttg
    16201 tttctaaagc tgataattca ccatttaaag gtaaatcttt atatggaaag gttaattata
    16261 caatatgtaa tggggagatt gtatataacg cctaatttaa gattattttt tttaggcgga
    16321 gtgtacaatg attgaaagta aaagattgta tattaggaga atgagattga ttaatcaaaa
    16381 ttggaagtat tagtttgaac aattagaaca taacatcttg gtaatttaga tatagtaagg
    16441 aagagaatcc tttttatgaa agaacgcact attatatttg gaaagattaa gttcctaatc
    16501 tatcatatat aatagtgcgt tatatattta agtatgtttt atataaacta atctaaaaat
    16561 cgaaaatctt tatacaattt ctacttataa attgccttta tagggtctag tttagaggct
    16621 ttaaaggctg gaatcagacc aaatacaact ccagtcaata tagtagctac aattgcataa
    16681 aataagctat ttaagctagg tatagcttca aaacctatat atttagaaac atagttagta
    16741 gcagtaaatc caactatagt tcctaaaatt ccaccacata ctgttataaa aacagcttca
    16801 actaaaaatt gaaataatat agacctaggt tttgctccaa tagcacgtct tataccaatt
    16861 tctctttgtc tttccataac agatacatac attatattca ttacaccaat accaccaaca
    16921 aacattgcaa ctacagttat tatagataca tatttgttta cattggaatt aatgctttca
    16981 agataagctg tctgttcagt tgggtctggt gtagtataag aaccattgat accagggtgc
    17041 atctcatata atttagctat aacattgttt gcaacttcat ttacattata gcctttagaa
    17101 gaaactaagt ctaactggta aatttcattt gaataagaat tttgactcat taaagtgtca
    17161 aaagcctttt taggtactag ggaagtagta aattgcatat cttggtaacc tccaaagaat
    17221 cctccagctt ggttttgctg agaatcatct aataccccta ttatttcaaa tatagttcca
    17281 tttatgttga taccatgacc taaggcatct tctggatttt caaaaatttc acttgtactt
    17341 tgtaatgtaa gtaaaattac ttttcttttt tcatcatcta aagaaaaatc tctaccacaa
    17401 attaaattta ttttagaatc tttttttact ggtccaacat caacatacgt agttttttta
    17461 tcaaaagatg cttgtgaaga gtaaactgaa tcaaggttaa acccatctct tgaaggagct
    17521 attctttcta ctccttcaac aaatgataat tcttctaaat cttttgcatt aaatggtttt
    17581 aaaaaaatac tcatatcatc agtaagacct gtgttatcgg ctgattcaaa cgaaatagta
    17641 gttttattag ggtttacatt gtttacagat ttcttaattt ctttttgaaa tccattacct
    17701 atagaactaa caagtattac tgaagttatt cctattataa tccagagtaa agctacaaat
    17761 acacgaagct tgtgaccttt taaattggcc aaagaatttt ttaataaact catgattaca
    17821 cctccgaagt aaacacacca tctttaagtc gtataacctt agttgcatac ttagttaaat
    17881 cttgatcatg tgtaaccatt attatagtct taccttgttt gttgagcctt gttaaaagct
    17941 ccataatttc tctgctagtt tcactatcta atgccccagt cggttcgtca gcaaagatta
    18001 tctgagggtc atttgctagg caacgtgcaa tggctacacg ctgttgttga ccaccagata
    18061 attgaagtgg tttctgctta agcttgtcca aaagcccaac agaacttaat ttatctttaa
    18121 caatttcttc tctattagat ttttttagtg ctttattgta aattagaggc aactctacat
    18181 tttgatatac atttagagtt tctattaaat taaattgttg gaaaacaaat ccaatattaa
    18241 tatttctaaa aacagaacgt tcattttcac tcaaattagt tacatctgtt ccatcaaata
    18301 tatatcttcc ttcatcaaat acatctagaa aacctaagat attaagtaaa gtagttttac
    18361 cactaccaga cttacccatt atcatgacaa attctccaga ttcaatttct aaatttaagg
    18421 attttaaaac atgtaattca tctttcccta ctttgtaata tttttgaata ttttctaatt
    18481 taattaacat atgtaaatta attcacatcc atagtaactt cttctacttt tttgtttgga
    18541 gtagtatctc cattattaga accagcagtt acgccatcgc cttgaactgg gtctccttct
    18601 ttcatttctt tagtagggtg ttttattatt atatcgcctt gttcaagacc gcctctaact
    18661 acagcaaaat catcattttg acttgctaca tctacaattt gctttttcaa tataccatct
    18721 aaatccttaa atacatatga gtgtttgttg tctttaagta cacaagatgc tggtatttta
    18781 aagcttgaat tagctacttc aagtgatgct tgaagatgga atccatttac taatccttct
    18841 tgattatcaa atgctatgtt tatatcataa taagatagtg tattctgctg agctcccatt
    18901 tcagtatttg gagtagatgg tttatcagat ataaaactta ttctaccagt aagcttttgg
    18961 tcagttgaaa aaactagtat attgaccatt tggtcaatct tcattttagg taaatcttgt
    19021 tcacttgctt gtcctttcat ataaaactct agaccttgaa tagtcataaa tgaaactggt
    19081 tggtctggat ttccagtttg gtcattcaag tatactgtgc catcaaaagg agcagtaact
    19141 ctgtcataag cttttttatc cagagaagct atctgggagc ttaaagcagt tatctgtgca
    19201 tttatagaag caatagcatc tttattttca gcaatatcag aaagtgatat tttttgtttt
    19261 ttgtattgac taagttgtga ttttaaacta tctatttctg ctattatagt tggattttta
    19321 gcagtaaaaa gaaggtctcc ttgatttact ttttgaccat ttgtaacatt aacatcactt
    19381 aactcataat ctccagatat attgaagtcc ttagtttgct taggaacaac catcccattt
    19441 ataaatattt tttcattttc aggaatagta tatgtttcga taaaattttc attagcttgt
    19501 aattcagtgt ttttcgaatc aacataagca agaactccta gaattaaaag tatgattact
    19561 gctattcctg catatatttt gaatctctta tttttaaagg gattgttttt aaaaccttta
    19621 tttttagact tgaagccact acttccaaaa ctgctatttc taaagttgtt acttttaaaa
    19681 ctgttatttc taaatctttt atttttaaat ttttttagaa aagacatgtc ttcctccttt
    19741 ttataaaaac tacttaatta tatactggga tgtacatata gaattactat aagaagttga
    19801 atataagtta atgaaaataa actatcaata ataagatact ataaatcaca tttgaatgta
    19861 atagtaaatt ttgtatattg gttgtactct gaatctacat caattttatg accaagctta
    19921 tcacaaagtt cttttactaa ataaagccca agacctgtag atttagaatt gtttcttcca
    19981 ttattacctg taaatccctt attgaatatt cgatttaaat cttccttttt tataccacaa
    20041 ccagtatctt ccactcttaa ttgtaaataa tttttggttc ttttgcaata gatagatata
    20101 ttatctccta atgaggagta ttttagggaa ttactcaata attgctcgaa tatgaagtat
    20161 agccattttt catcagataa aaccttaaaa ttcaaattat ttaagtctaa aataattttt
    20221 tttgaaataa aatattttga gtattttttt ataatatttc taatgatttt ttcaatattt
    20281 acctcttgaa ttaaaaaatc cttatgaaaa tcttcgagtc ttgataaata taaaattttt
    20341 tcaacggagt tttcaattct aaatatttca ctatctatgt catctgaaat tttttcatca
    20401 attaaatttt cattttgttc aagaatgagt tttattatag ctataggtat ctttacatca
    20461 tgtacccaca tatttaaaat ctctttgttt tcttcaaatt tctcgatatt attatttatt
    20521 atgttattac attgatattg atgattttta ataatgttca agtatatttt ttcttcattt
    20581 ttacatctag ctaattctat atcattcata ttaattttga atgtatcatt ttttatctta
    20641 tctaaaaatt tgttcttctt gatgtagcta ataaatagat ataaaaataa aaacacaaca
    20701 tttacaacta atatatataa aatagtatca gtcagaaaaa catctacagg agaaaatata
    20761 ataactgata ctgtaaaaat taagaaagta aaattgtata ctaaaaaacc tagtttatcc
    20821 ttgagaaaat ctttaaagct cataaattca cctacttaga attgttttaa ctgattatat
    20881 aacccaatcc tctttttgtt tctataaaat cttctaaacc aatttcattt aactttgagc
    20941 gtattctatt tacattgaca gttaatgtat tatcatctac aaaccaatca ttatcccata
    21001 attttttcat gagtttattc ctacttacta tctgcccctt atatttcata agctcatgaa
    21061 gaattttgat ttcatttttt gttagctcaa tagtattatc ttcatagttt attgttgcag
    21121 ttgataaatc taaagtaaca ccattgtgaa taatctgatt tgagttatta tcaacaaaat
    21181 tataagttct tcttaaaagg gcattaactt tagctactaa gacatctaca gaaaaaggtt
    21241 tttgtatata atcatctgca cctaaattta cacccattat tacatccata ttagaatttc
    21301 ttgaagaaat aaaaattata ggaacttttg aaatttttct tatttcatta caccaatgaa
    21361 aaccatcata aaatggaagg tttatgtcca ataaaactaa ttctgggtta tagtttttga
    21421 actcttctat tatattttca agattttcta tttgatgaac atcatgtccc catttagtaa
    21481 gacactttgc tatgatattt ttcaatgaga cgtcatcttc aactaccatt attttaaaca
    21541 ttcttacctc ctaattcaaa atagttatat taacataact atattctact tgataaatta
    21601 aaatatttct accttattac ctaaaataat tatattaata taactatatt ttacttgata
    21661 aattatattt taaacataat tgcaataaat ttgaagaaat ataattaata cttacgaaaa
    21721 tgtaacctta aattaatata attaaatgtt taaaagccat tttaatatat ataatatatt
    21781 tgtgagaatt gataaataac taattgtgat gaaaggtgat tattaactat ggaagaaata
    21841 ttatctgttg aaaatataaa aaaggagtat ggaagaaaag gttcaaaaca tgaagctcta
    21901 agaggaataa ctttcaaggt ttataaagga gaatttgttg gtattatggg gtcttccggt
    21961 gctggtaaat caacactttt aaatattatt tctacaatag atttaccttc atcaggagat
    22021 atttatataa atggaaagaa tactattaaa atgaagcaaa atgaattggc agattttaga
    22081 cgtgataatc taggctttgt atttcaagat tctaatcttt tggatacact tacaataaaa
    22141 gaaaatataa tgttgcctct ttctttaaaa aatgaaagag tatcagtaat agaaaataga
    22201 ataaaagaga tttcaaaaga attaaatata gaatctatat tagataaata ccctggcgaa
    22261 gtttctggtg gacaaaagca aagaggagct gtatgtagag ctatagcaac aaaaccatca
    22321 ttagtacttg cagatgagcc tacaggagca ttagattcta aatctgctag ggatttgttg
    22381 aattgtctat taaaattaaa caaagacagc aataaaacaa tattgatggt aactcatgat
    22441 gctataagtg cgagtttttg caatagaata ctctttataa aggatggaat aatattcaca
    22501 gaaattgtaa agggagaaag taacagagag ttctataata aaatagtaaa tacagtttcc
    22561 ttaattggag gagttaataa aaatgacttt atttagaatt gcaatgcaaa atgtaaagaa
    22621 tagttttttt aattatttaa tgtactttat ttcaattgta tttagtgtat ttgtattttt
    22681 tagttttaaa tctatagagt ataatgaagc gttgagttca cttggagaga aaactaggat
    22741 gagtattaat acaagttcaa ttgtaatagt ggtatttgta tttttattta tatattattc
    22801 aaactcattt tttttcaata gacgtaggcg agaagtagga acttatagtt tacttggaat
    22861 gaggaaaaat cagataggaa aaatattttt atatgaaact tttttgatgg gtatagttgc
    22921 aatactaata ggtatatttt taggactgtt attttcaaag cttatgacta tgatgcttgt
    22981 aaaattaatg aatgaaatga tagtagtaaa tatgaactta agtataaagg ccttagttca
    23041 gacactagcg gtatttttaa taatattcat agttattgga ataagaaata ctatagttat
    23101 cagaaataag agaattatag agttatttaa taaatatcca gaaaagtata agtttaaaaa
    23161 atttataaag ttaaaatgtg tacttggtgt tttattaata gctatttctt atttaatgtc
    23221 aattagttat tttattgctg aaaatattat gctttcagtt tttatattag ttacaataat
    23281 acctggaact tttttatttt tttcatcaac gatgtatatg attattgatg ctgttaagaa
    23341 gagaaaaagt ttttattata agggacagaa tttaattgca ttttctgaac ttggatttaa
    23401 attaaagagc aatagtagtg tattggctgt aatagcaata ttaatagcta caagtgtaac
    23461 tatgctaggg tttaccatat cactttatta cgatatagat aggaacataa gtgaaaatta
    23521 taaatacagt tataccataa atttaggaaa ttcttatgta aataacgaaa ttgacaaatt
    23581 attatataaa tataaaaaag ataataagat aatctttgat aaaacaatag aacttataga
    23641 caaagatata aatattgaaa tgtattataa aaatggaaat agttatatag aagatagaac
    23701 gtctgtagat attattagag aaagtgattt taaaaaatta agacaatatc agaataacaa
    23761 ttatgaagaa ttaacttcaa aggaatctgt gtactatgtt tctgattcat acaaaaaaat
    23821 attttttaaa gactttgagg ttgaaaaaat aaacttgcat attaaagata caaatgagta
    23881 tgatataaat ctgtttaaag tacaaaaaag catcttggag ccagaaataa attcacaagc
    23941 tacgtttgat ttaattgtag caaaagatga cgtatttaat cagttaaaat tacatggaaa
    24001 ttctagatta ataagattaa ttgatataaa aaatgaaaaa aaagaactgg atttgacttt
    24061 aaaattaaaa aatatagtaa gtgaaaatat gaaatttact tatcctttta attttacatc
    24121 aagtattgaa agttataata acttgataaa attaagtggt ctaatgctgt ttataggcat
    24181 atttttgtct gtagtatttc ttttatgtac aggtagtata atcttattta aacaattatc
    24241 aaatatatat gatgataagg aaagatatat tatgttaata aaacttggag caaataataa
    24301 agatattgag aaaataatat caaaacagtt aaaagttata tttttaatgc cattagttgt
    24361 aggtacagtt cataatttat ttgctatgtc tatagcacaa aagtttatac caaggtcatt
    24421 acttgtacca attatcataa ctctagtcat ttattttata ggatatttta tatattattt
    24481 tttaacttta aaatatgctc taaacatgat aaaagaataa attattttta agtcaaaaga
    24541 attagatata tgttttgaat aaaataactt atttaagtgc agatagaaaa tactagaatt
    24601 gagtttaaga tatttattta aagacaaaat taaagttagg aaaaagtcta tattttatat
    24661 cattttgtat cagttacatt acttgatgtt atataataaa tctaagcaga atatcaaata
    24721 aaaaatgacg aggagctgaa atttatgaag tttaatgcct accaacataa atactcatca
    24781 ataagaaatg tcgtgtatgc taaaaatgga gcagttgcaa catcaacacc attagcatct
    24841 caagctggac ttgaaatact aaaaaagggt ggaaatgctg ttgatgcagc agttgcaaca
    24901 gccgccacat tagcagtagt agaacctaca agcaatggga ttggaggaga cgcatatgcc
    24961 cttgtttgga tagaggaaga aaaacgattg tatggtttaa attctagtgg ctttgctcca
    25021 gaaaatatgg aattaaaaaa ttataataat atgaaagaaa tgccaaaata tgggtttgga
    25081 gcagtaactg tacctggaat accagcagct tggtcagaat taaataaaaa atatggtaaa
    25141 cttagcttaa tggaatgctt atctccagcg ataaactatg caagagaggg atacgtagta
    25201 tctcctaatg tagctaaggt atggaaaaaa tcatatgaac tctatgaaaa agaacttatt
    25261 ggagaagagt tcaaaccatg gtttgataca ttttctaaag atggtaaagc tccagaggct
    25321 ggagatatat ttatatgtga agaacaggca agtacattag aagagatagc aaatactcag
    25381 gctgaaagct tttatagagg aagacttgct gataaaatag atgaatattc taaaaaattt
    25441 aatggggcta taagaaagag tgacttagag tgtttttatc caacatgggt agaacctata
    25501 agtacagaat ataagggata taaaatattt gaaatcccac caaatggtca tggaataaca
    25561 gttttaatgg cacttaacat attaaaagaa ttggaattag aaggaaatat agaaaatgta
    25621 gaagacatac ataaaattat agagagttta aaattagctt ttgcagattc taaaacatat
    25681 gtaactgata tagagcatat gaaggtaaag attcaggaat tactaagcca agagtatgct
    25741 aaaaaaagaa gtttattgat tgacaataaa gaggctttgt atccaactgc aggagagcca
    25801 tattgtggtg gtacagtata cctttgtact gcagataagg atggaaatat ggtttcatat
    25861 atacagagca attacataaa ttttggttca ggaattgtga taccaagaac tgggattgct
    25921 ttacatagta gaggaaataa ttttaattta gaccctaaac accacaatgt agtaaaacca
    25981 tttaaaaaac cttatcatac tataatacct ggatttttag gtaaagaaga taaagcaata
    26041 ggtccatttg gtgtaatggg agcttttatg caaccacaag gacatattca agtgttaaca
    26101 aatatgattg attttggatt aaatccacaa gaggcgctag atgctccaag atggcagtgg
    26161 ataaaaggaa aagaaataga agttgaacca gagatgccaa agcatataat agattcatta
    26221 attgaaaagg gtcatgaaat aaaagtaatt catgatactg tcgacatggg acgaggtcaa
    26281 ataatattta aaacagaaca ggaaagttat atttgtggga cggaatcaag atgtgatggt
    26341 catattgcag tttattaata ttatcaacta aaatatatat aataaattta aagagtatat
    26401 gaaataataa gtaaaggcga aagtctacaa tgactgacgc ctttacaaaa tttaagctat
    26461 catatgctga ttttatatag attatgagcc ttattcttga ccagttttga tttcattgtc
    26521 atcataacta atccagtcac taaagctacc aatataaatc ttgtgaggta tatccagttc
    26581 tctaagagca agactgttaa cacaagcaga tatccctgaa ccacaagata aaattacttc
    26641 atcataatta tttaaatctt taaagaattt ttttaaaaat tctatatctt taagtgagcc
    26701 attttcaaag tcacttttta ttaaatcctt acaaaaataa ttttttgcac ttggtatatg
    26761 accagctttt gagtaagcag gttcaactaa accctggtat ctctcattag cacggcaatc
    26821 tattattaca gtatcttttt tgtataattt agatttaaca tattccattg gaacaactaa
    26881 atcattgttt atatttggtc taatttcctt acctgtacaa cttggtatat tcactttctc
    26941 ttccaattct ccaccttcct ttacgaaaga tgttattccc ccatctagta catagacatt
    27001 tttaagcccc aaatgtttta attggaaaaa taatctgcaa gctccattta aatctccatc
    27061 atcataagtt acaatcgtag tgtcattatc aacacccatt ttttctaatt tttcttttag
    27121 tattaaaggg tcttgtaaag gatttttacc accatgttct tttgtaggag atgataaatc
    27181 cttgtctata tctaagataa aactgccttt gatgtgtcct tttttataag aatcaatacc
    27241 ataagttcta ttgataagat caaatctaca atctattaca actagattat catttttttc
    27301 tagttttgat ataagttctt ttgctgaaat aatgtttttc aaagaatgta cctcctgtgt
    27361 ttatattatc tttattttaa tttatattaa ttattaactt tataaactaa tattattata
    27421 atttattaca taagtaaata aatctttaga aattgtaaaa attttatata aaaattcaaa
    27481 taattaatga atattgaaaa ttttagatat ataataaaat aagagtatat tttatacaat
    27541 atgaaagctg gtattgcaat agattaaagc cttatacacg tttagttttt aaagaaatta
    27601 gtgttattat gaaaacctaa gttaatttat taaataaata attgaataaa aaaattttat
    27661 tatgtattta taaaattttt gttacaaatt tggcataata tagtatactt taagtgtgta
    27721 ttaggttaaa tctataacaa attagacgta tgatatagac ttagtgttta ttggcattta
    27781 caagaaattt gttaatatca actatttgta gtttgggcag ttataattat tatagggggg
    27841 atgtccaata caaaacaatc aaccaagaac taatattata ttataaagag ttatagtttt
    27901 gtgtgtttat gtttttaatt aaatttaaag tgggaaaaat atatttgtta gaatggagaa
    27961 tagcgagatg agtaataaaa tagttagtaa gagacaatta acagatagta tttatttaat
    28021 ggaaatagag gcacctagag ttgcaaaatc ttctcaacca ggtcaattta taataattaa
    28081 aaatgatgaa aaaggagaga ggattcctct tacaatagct gactatgata gagaaaaagg
    28141 aacagtaact attgtattcc aaacagttgg tgcttcaact aaaaagttag caatgtttga
    28201 agaaaacgat tttgtaatgg attttgtagg gccattagga caagcaagtg aatttataca
    28261 tgaagatata gaagaattaa gaaataaaaa gatattattt gtagctggtg gagttggttc
    28321 tgctccagtt tatccacaag ttaaatggtt taaagagcat ggattagatg tagatgtaat
    28381 aattggtgca agaactaaag aattaattat attagaagat gatatgaaaa aagtagctaa
    28441 aaatgtatat gtatcaacag atgatggtac atatggattt aatggaagag ttacagacct
    28501 attaaaagat ttagttgata atcaaggtaa aaaatacgac caagcaatag taattggacc
    28561 aatgataatg atgaaattta tgtgccaatt aactaaagag ctaaatatac ctactatagt
    28621 aagtttaaat acaataatga tagatggaac aggtatgtgt ggtggttgta gagttagtgt
    28681 tggaaatgaa actaagtttg catgtgtaga tggtcctgaa tttgatggtc atttagttga
    28741 ttttgatcaa gcaatgagaa gacagtctat gtacaagact caagagggaa gagctatgct
    28801 aaaacttgaa gaaggcgata gtcatcatca tagtaattgt ggatgtggag gtaacaaata
    28861 atggatgcta aaaaagtaaa agtaccagtt agagaacaag aacctgctgt gagagcaaca
    28921 aattttgatg aagtatgctt agggtataat aaagaagaag ctatggcaga agctaataga
    28981 tgtttagctt gtaaaaaacc aaaatgtgtg ggtggatgtc cagtaggaat cgacatacca
    29041 gggtttataa caaaaattaa agaagatgat atagaaggtg ctgctaaagt aatagctaag
    29101 agcagttcat taccagctgt ttgtggtaga gtatgcccac aagaaagtca atgtgaaggt
    29161 gtatgtatac ttggaataaa atcagatgct gtatcaatag gtaaattaga aagatttgta
    29221 gcagattggt caaaagaaaa tgacataaat ttatctgata cagagcctaa gaaaaatcaa
    29281 aaagtagcag taataggaag tggtccagcg ggtctagctt gtgctggtga tttagctaaa
    29341 aaaggctatg atgtaacaat ctttgaagca atgcatgagc caggtggagt tttaacttac
    29401 ggaatacctg agtttagact tccaaaacaa gctgttgttc aacctgaaat agacaatata
    29461 agaaaattag gtgtaaaaat agaaactaat gtaattgttg gtaaaacaat tacagtagat
    29521 gaacttatag aagatgaagg atttgaagct atattcatag gttcaggagc tggtcttcca
    29581 atgtttatga atataccagg ggaaaatgca aatggagtat tttctgcaaa tgagttttta
    29641 actagagtaa acttaatgaa ggcttataga gatgattatg atacacctat tagttctggt
    29701 aaaaaagttg ctgtagtagg tggtggaaat gttgctatgg acgctgctag aactgcatta
    29761 agattaggtt cagaatcata tatagtttat agaagaagtg aaaaagagct tccagcaaga
    29821 gctgaagaag ttcatcatgc aaaagaagaa ggcattatat ttaatacatt aacaaatcct
    29881 aaggaaattt tagtagatga aaatggatat gttaaaggta tggtttgtat aagaatggaa
    29941 ttaggagagc cagatgattc tggaagaaga agacctatag aaatagaagg ttctgaattt
    30001 gtacttgatg tagacacagt tataatgtca cttggaacaa gcccaaatcc actaatatct
    30061 tctacaacaa agagtcttga tataaataag aagagatgct taataacaga tgaaaatggt
    30121 cagacttcta aagagggtgt atttgcaggt ggagatgctg ttactggagc agcaacagta
    30181 atatctgcaa tgggtgctgg taaaacagca gcagcatcaa tagatgaata tttaaaagca
    30241 aaagttaatg cttaatttgt aaattaaaga gagggtgtct caaaatgaac tttttagttc
    30301 atgaggcact ctttttgtac aaaatcaaat atgttttaat catttcaaca atgaaaattt
    30361 cattcctgta gaaagtctaa cttttaggtc ttagtacaat ctctattttg atgtagccac
    30421 ttttttagat ggtttaataa tttatcagtt attattgtaa tatttgatac taagtaacat
    30481 aactttgtct aactatgata aaatagttat acaataaagg tcttgtaagg agtgaataat
    30541 gtgtggctaa taaaatcaga tttgtcaaat ctaacattaa ataatagaaa aataaattgt
    30601 gtaattaatg gtattttaat atgaaaaaaa gagaaaaagt atttgatggg ctagttttta
    30661 agcatatatt aatcttatta atactattag ttttgattga tttaacaagt accatcatat
    30721 atgcaagtaa ctctatggaa attacttcta gaaatatgat tgaggcatca aaaagagaac
    30781 ttgaaaacta tttagaagta aacatatctt tattaaaagc tcttagtcaa gatgatagat
    30841 tttctaatgg tgaaacatca ctaattgaaa agggaaaatt attaagtcca tatcaaaagg
    30901 aatataatct ttttatgatt ggtataacag atacaaaagg aaatgcttca agtacatata
    30961 gggaaaatgt taactcaata aaagataagc ctagttttga gaaagcaatt aaaacaaagc
    31021 aagtagtagt ttcagatatt gaagtcagta atgtaacagg tgacaaagta tttatcatat
    31081 atgtaccaat tgtaaaaaat aatgagatga ttgggaccat ttttgcttct ttttattttc
    31141 aagatgtaaa taatttaata agtagaagca attttgatga ttctattaaa tttctaatga
    31201 tagataaaga ttatactatt atttctcatc caaacaaaaa atatgtaaat gataaaagta
    31261 agatgcttga tttagaaggg aatattatag gaaccactaa aagtgaaatc ttaaaaaata
    31321 taaataaaaa atgtcaaggt gattttttat cttgggataa ttggagatta tataatgtaa
    31381 aatatacgaa cataaagtgg actaattgga ctttagtatc aaaatgtaat atatttaaga
    31441 actttaaaaa tctaatagtt aattttatga taaagttgta tttttatata gtaatattta
    31501 tgatattgtg gaaattaagt aatgctaaat taatagaaca acttaaaaaa ttggcttatt
    31561 atgattcttt aagtggaata aaaaataaag aaaagtttag aaaagattct atgtatattt
    31621 taaagaatta ttatcaagat aatttttact tagtacaatt ggatgtcaat aaatttaaat
    31681 atataaatga gatgtttgga tatgctgaag ggaataagat attaattcat atatcacagg
    31741 ttttaaataa taatacaaat aaatatgaaa tttgtgctag gatggataat gaccatttta
    31801 tattgttgat tgcttgtaac actgaagatg aacttttaaa tagattatct aaaataaata
    31861 aagaaatttg taacttaaat actactaact catctaagta taaaattgtt atgtcaagtg
    31921 gaatatataa gattactaaa aaggatgata ttaaaaagat tgacttgtta attgatagag
    31981 caaatattgc agcaaaaagt aaaaaggaaa aatatgaaca ttcatattca ttttttaatg
    32041 aagatacaag aaatcgattg tacaaggaaa aacgattgga agataatatg aataaagctt
    32101 tagaaaaagg tgaatttata gtatattatc aacctaagta tagtttagat gatgtaaatg
    32161 aaattgaagg agcagaagcc ttgataagat ggaatagtcc agaatttggg tttatttcac
    32221 ctatagattt tgtaccttta tttgaaaaga atggttttat tgtaaatatt gatatgttcg
    32281 tgtttgaaga agtatgcaaa acattaaaca agtggataaa taaagggtat actcctgtac
    32341 caatctctgt aaatatgtct agagttcatt tatataggga taattttata gaaaatataa
    32401 ctgatttgat aagtaaatac aatatatctc ctgagtttat tgaacttgaa ctaacagaaa
    32461 gtgttgtgtt tgataattta aatatattga ttgatataat gaaaaagatt aaagagatag
    32521 gattccttat atcaatggat gattttggtt cgggatattc atctttaaat ctgttaaaag
    32581 acctttcttt tgatatttta aaattagata gaggattttt aatcgaaaca acagatacaa
    32641 aacgtggaaa aattattatt tctaagattg tggaaatggc aaaagcgatt gatattaaag
    32701 taatctgtga gggcgtagaa acttatgaac aagtagagtt cttgaaagag ataggttgtg
    32761 ataaggttca aggatactta tttgctaaac ctatggtatt agatgaattt gaaaaacact
    32821 taaactttaa atttgattaa tcattaataa ttattagact ataatatacc ctaacaactt
    32881 acttacaaat atgtaagtta attgttaggg tatttttatg gttaaagtag tatattcacg
    32941 atattatggt attgtagtaa aaataaaaaa ttatggagaa tataaaatga acatattgag
    33001 tattagaaat atatcaaaaa catattgcgg aaatattcca tttaaagcat tagataaggt
    33061 tagtctaaat atagaaaagg gagaatttgt gtctgttatg ggaccatctg gaagtggtaa
    33121 atctactctt ttaaatataa tatctacagt tgatagacag agtgaaggtg aggttgtatt
    33181 agatggatat gatgtaagta aattgaaagg agaaaaactt gctgaattta gaaggaaaca
    33241 acttggtttt gtatttcagg attttaattt gattgacact ttaactgttg gcgaaaatat
    33301 tatgttgcca cttacactag agggggcaag tatcaaagat atgaatatac aaactaaaag
    33361 tatatctaaa tttttaggaa tagataaaat tttagataga aaaacctatg aaatttcagg
    33421 aggtcaagct caaaggtgtg ctattgctag agctattata aataaacctg ccatacttct
    33481 tgcagatgag ccaactggaa atcttgattc aaaatctact gatgatgttt tgaaattatt
    33541 tactaggata aacaaagaac aaaaggtaac aacacttatg gtaactcatg aagcatatag
    33601 tgcaagttat tcagatagag taatttttat aaaagatggt tgtatatata cagaaataaa
    33661 aaaatctgaa agcagtaatt ctttctattc tgatatacta gctgttttgt ctcaaatagg
    33721 aggtgtaaga tagtggattt tagaaagttt gcttataata atatagttaa aaatttcagg
    33781 gcatatttag catatttttt aagttctgtt ttttctataa tgatattttt tgtttttgca
    33841 gtgtctatgt tccatccaat tataacaaaa tctggaatgc agagtggttc tactgcattt
    33901 atggctctta tgacttcaga attaataata ttcggtttta gtctactttt tatattgtac
    33961 tctttaggaa atttcttgaa atatagattg aaagattttg gagtattgat gataattgga
    34021 atgagtaaca gacaactgaa aaaattgata ttaattgaaa atttgataat aggattttta
    34081 gcagtgatgt taggaatatt acttggttta tcaatttcaa aattgttttt attgtattta
    34141 agcaaactgt tttatatgaa tttaactgaa ttttattttc cagtaaaagc aatgctattg
    34201 actattgtat catttatgat tttatttttg ataacaggac caatgagctt aaaattattg
    34261 agtaaaaaga gcattttaga gcttttagta ggtacaaaaa agcctaaaaa agagataaaa
    34321 tcttcaaagc tatttggaat aattggtgta atatgtctta tattaggata tgctatgata
    34381 ctatttggca ataagttaaa aataaatgga ggtatgtata caacagcact attaattact
    34441 ttggggatat ttttattttt ttctcaattt actattttga tattaaagta tttaaaaaat
    34501 aaagaaaaat tttataagaa caaagtaaat atgttactta taagtaattt gatatataaa
    34561 ttaaaggata atacacgatt gttattttta ataacaatac ttttatcggc tactttagta
    34621 gcatttacaa caacttcaac acttgtaagt tctcaaggag aagcttctaa aaataatttt
    34681 ccaatggttt actcatattt ttcagagcat aataatgaaa aagaatatga agaactacaa
    34741 caaattagag aagcaatcaa aggatatgat tataaggagt taagttttcc tgtacttaaa
    34801 tataataggg aagtcttact aagtgtaaag aattataaca aattatcaaa ggaattggga
    34861 ttagataaaa ttagttcaaa gttagaaaaa tatgaagggg ttataattcc tagtagcaat
    34921 tcacaagaac atataaattc tttaaaacaa ttaaaaaatt atagtataaa aaatttaaat
    34981 atagaagtaa aaaaatcaaa aaataaaata atttttccta caggactgtt tagtaaagtt
    35041 gtagttataa gtgatgactt atacaatgaa gtaaaaggtg aattttcaaa aattaatttt
    35101 catggatttg attataaaaa ctggcaaagc agtgcacaga taactgaaaa tttaaaagaa
    35161 aaacatttta atttggatag agaatataac aggtcatatt ttttaacatt accagatatg
    35221 tatttagtag agttacaaca aagtaaaatt cttcaattta tgggtgtttt tataggagtg
    35281 atattattta tagcagtttt tagtttttta tactttagat tatatacaga cgagatagaa
    35341 gataatgtaa agtacaaaaa actatcaaaa ataggtctat cttttaaaaa tatgaataag
    35401 attgttagta tagagatagg tacattgttt tttataccgt attttatagc aattataaat
    35461 agcataattt ctttactgtt tttaaatcaa gtattaaata atagttttaa gttagaaaat
    35521 ttgggtatat tactactgat atcatctata tattcacttt atttttactt attaaaaaaa
    35581 atttatacta gaaaagtttg gttttttgat taaagtggta tataatagat atataaatta
    35641 atatttaaaa agtagttaat attaggggag ggcatttgca cctcccttgt aatatgtgga
    35701 aaattgaata ttagaagaag gaggagactt gatggaaaat caacaattat taggaacaga
    35761 acgaattagt aaattactac taaaatattc tataccagct ataataggta tgttggtaaa
    35821 tagtttatat aatgtagtag atagaatttt tattggaaat ataccagggg ttggaccact
    35881 tgcaataaca ggtcttggtg taacaatgcc aataatgaca ataatacttg catttgggat
    35941 gttgataggt ataggaacta ctactaccat atcaataaaa cttgggcaag gtaaagtaga
    36001 agaggcaaga aaacttatag gaaatgcaat gacgttatct gtaataacag gaattatcat
    36061 aatgatactt ggaatattat ttgcaaataa aatacttaca ttgtttggag caagtgaaaa
    36121 tactttaata tatgcaaaat catatatcaa tattatatta ttaggtacag tagtaaatct
    36181 tctttccttt tctttaaacc actcaataag agctgatggt agtcctaaaa tttcagcagg
    36241 aataatgata gtaggatgtt taactaatat agttttagac tggatattaa tatttggatt
    36301 caatttggga atacaaggag ctgcaattgc tacagtaact tctcaggctc ttacagctat
    36361 tttaactata gggtattata taagtggaaa atcaaactta cgattcagta aatctaatct
    36421 aaaattagat aaaaagctaa taaaagcagt gtttgcaata ggtatgtcgc catttgctat
    36481 gcaacttgca gcaagtttag ttcaagtaat atcaaatatt gcacttaaaa ctcatggtgg
    36541 agatttagct ataggggcta tggctactat ttcttctatt gcaatggtat ttttgatgcc
    36601 tatctttgga ataaatcaag gagcgcaacc tattataggt ttcaattatg gagctgaaaa
    36661 atatgatagg gttaaaaaag catatttagg ttcattagta gtagctacta taattttatg
    36721 tatgggtatg gtagtagtta tgcttttccc agaagctatt ataggtatat ttaataaaga
    36781 ccctgaactt atgaatatat ctgttaatgg attaagaata tacttactta tgttgccaat
    36841 tgtaggctta tcagttacag gaacaaactt tatacaatct ataggaaaag caaaaatggc
    36901 tatgttattg agccttttaa gacaagtaat tttattgata ccagcagtat taattcttcc
    36961 tacattctta ggtttacagg gtgtatggac agctcaacca gtgtctgatt ttatagctac
    37021 agtaattaca ggtatagttg tatttagaga attaaaaaga tatactccta aaactgaaaa
    37081 attaaatgaa aatgaaagac taaacgagat aactactgag taaaaatata aattcagata
    37141 attgagcaag aaattgcaaa aaatacgatt atatgataaa ataaaaccgc tgtcaaggat
    37201 aagagaaatt ctaattatgg agtgatttta tggaatttac aaagaaaagc aaattaaaaa
    37261 atatgtatgt aaacatgaat gtagctagaa tgttgtctaa gataaatgag tataagggta
    37321 gacaactgct ttacaaaaaa caaccaaaag aaattttaga aaacttagaa aaaaaatctt
    37381 tagtagattg ttctgaatct acatacattg gaaatcaaag agatagtagt aattttaatc
    37441 tagaaaagtt gataagtaat gaagttacac ctagaagtag agaggaattg agtattgttg
    37501 aatacagaga tgtggtaaaa actattaaca gtgcttatga gagtattccc atcagttcac
    37561 aaacgattct tgagcttcat ggatacttat ataaattttc atctactaga ggaggaagtt
    37621 ataagtcaga taatgatttt attgaacaca atttaaaacc tagcgaattt ataagtattg
    37681 attcaagtgt caataaagtt gaaaaagctg tagaagaaat atgtgaagct tataatacat
    37741 tgatagagga agatgaaatt gatatattaa tattaatttc tgcatttgtg ttagatttca
    37801 tattgataca tccattcaaa gaaggtaata taaaaatggc gagagtactt atcctattgt
    37861 tactaaataa aaatgggtat gaagttggaa gatatataag tttaggaaag atatttgatg
    37921 atagttcata tgaatattat agtaatttaa attatttgaa agcctcaata ggtagtgaaa
    37981 aagcagatat gaatgcatgg attgagtatt ttttagagac gatattaact gcatatgaga
    38041 agctggatga tagtttaaat atatctgata agaaaagaca aacaaaaact agtagaatag
    38101 agaaaataat aaattctacc cttggatatt ttacaaaaga agatataaga gatttatgtc
    38161 ctgacattcc agaacctact ataaatagag tttttaataa tctaagaaaa caagataaga
    38221 tagaagttgt tgcaagagga agaagtgcaa aatggaagaa aaaatattaa aaaatgttta
    38281 gataactaaa atggtatagt gttttacact ataccatttt taatgtcatt agcatgagca
    38341 ataatttaac aacttaagca atatcaattt tatttattga ttatttttga actgaaaaat
    38401 ggcgttatat ggtatacctc agtggtaatt aattttggat gagaagatat aatattacag
    38461 aatatattag gagtatatgt agaaaaaata taataaaagt gtgaggctta gtaattaaca
    38521 aattatgtgg cttcacactt ttttataaaa taaagatact tagcagaaga atattttagt
    38581 tgatatgttt ataagatggt acttgtttgg gtaaaagtat aaatagtaaa aaagtagaag
    38641 taatgtgtat aaaaacgtaa gttacattct gtaataatag ttattttata attcaacaaa
    38701 agaatagaat gggtatattt gtgaaataat aatataaaat aatcttagga gtgagcttat
    38761 gaagaaaaaa ttattatata taaatgtaaa ttcaaaacct gaagacttat cttcaagtaa
    38821 aactgtagca agaaaattta taaataaatt tatggaaaaa aataaagatt ttgaggttga
    38881 agagatagac ctttataaag aacatatacc aagacttgag tatcagtact ttgaaaaaag
    38941 aaatagcata gttagtgaag aaaatgctaa aaatttagac gataaggata gaaaagaact
    39001 tacaaagatt agaaatcttt gtgaccaatt tgtgagtgca agtgtatatg taatagcagc
    39061 acctatgtgg agtttatctt ttccagcacc acttaaagag tatatagatt gtataattca
    39121 agatggaaaa actatatctt ttgaaggcaa tgataaacca caaggaattt taaatgatat
    39181 tgatagaagt atggtatata tacaatcttc tggtggacac ataccatggg tgttgaagcc
    39241 agttatgaat aaagggttaa attatgtgga aagtattatg aaatttatag gaattaaaaa
    39301 atttgatgaa ttgttagtag atggaactgg aactagtgaa gaagaaagac aagctgctat
    39361 agaaaaagca gctgaaaaaa tagatggtat aatagatggg atgaaatttt aattataata
    39421 ttttattaaa aatataaagg aaaaacctct tttaatgtag aaacttatat tgaaggaggc
    39481 gagaatcatg cgagaagaaa aaagtaatga aaagtatgat tgttattggt gtaatcaaga
    39541 gaataatttc tgtgtagaaa taaaagataa tatagtcatg atagatgatg gcactggtac
    39601 gttaaaacaa gccgttttca tagggtataa acaaatccaa attaatttaa actgttcaca
    39661 ttgtcaaaac ttgaatagaa taaaattaaa tttgtagaat tttaaaatgg aaattattga
    39721 aggaattaaa aatagaaagt gttaatattt agactgaaaa ttatatttta tacaataaaa
    39781 gtttatttaa ataacattgt attttaatat ttattttcag tcttacttta ttaaaattat
    39841 tttttggtta tgtctggaaa atatctgtct actaattttt ctgaaatatt ttttaattgg
    39901 tcagccattg aagtcagact taataaggct atcaataaat catctttatt ttctggattt
    39961 atactaatat tttcaaaatt agactctata aagtccggta tattctttct ttgattttct
    40021 tttattaaca tgaatttttc gtaacatgaa actaaatctt tttcactgaa attatccttt
    40081 tcatacacac catgtaagat tcttttaatt tcttgtattg taagtgtatt tttcatagaa
    40141 taaataatta tcatctgtaa aatttgttct ttagtatact tttttccctt aactggtttg
    40201 attaatccct ctttgctgta attatttatc atggttttag taagaatttt atcactttca
    40261 aatcttttat tggcagaaag cttattgtca attagagaaa taatttgatc catatataag
    40321 tcaatagatg gaatatcgtt tgaagttata tctgcattat ttagtgtttc tagtattata
    40381 gtattaagtt cattattcat catatgttac ctccataata tatataatac actaaattag
    40441 aaagtaaaac aatattaagg cttgtaaaaa aaacataaag tggtataatt aaatatataa
    40501 tatagtaatg gaaactatat ttgtgaatct gatttttaaa atacataatt gtaggaggac
    40561 gaaatgtatc aatttttttt aaagggtaga gacccaataa gcagtttaac tcattttata
    40621 ggtgcttgtt tatctctttt agcaactata attttagttt ttcaatctgt tacattacag
    40681 gaaacttctc tcttgatgat agtatctgta tcggtatttg gattttcact aattgcttta
    40741 tatagcgcaa gttcgtatta tcatttttta aaggggacac cagaacaaga attgtttttt
    40801 agaaaagtag accatgcaat gatttacgta ttgattgctg gctcttatac accaatatgt
    40861 ctgaatttta tggaaaaaaa agaaggcata atatttgtta cagcaatatg gatagttgca
    40921 tttattggta taataataaa aatattttgg atggatgcac ctagatggtt atctaccagt
    40981 atatatttac ttatggggtg ggcaattgtt tttgatataa atgcattcaa ttcaattcct
    41041 aaggattgcc ttagactatt aattatggaa ggtgtatctt actctatagg tgcaattatt
    41101 tatataatta aaaagcctaa tataagtcct gagtttggat ttcatgaaat atttcatatt
    41161 tttattatga taggttcttt atttcacttt ttagcagttt tattgtatgt tttatagttt
    41221 taaaagattt gattaattga tactaaaatt ctacaatgaa taaaatggaa ctgccttata
    41281 tagattatat cttcgacaat aagacagttc cttattataa atattaaatt ctacttataa
    41341 taaaattttg ataaaaatag tccattcaaa atgcctattc cataattcct ttaatgtact
    41401 tttcatttac gacatatagt ttgaatttat gtactataat tatatcctct aaattctctg
    41461 aaacactaac aattctgaca catttgtttc taatttctac aggtaaatct aaatcatttg
    41521 ttaaattcac atagtcatca tatttataca taaaatcatc cctttacatt aagatatact
    41581 tattatacta tattttaata agttttttta aattattaca attt
//
LOCUS       DAMJWC010000033        40748 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMJWC010000033 DAMJWC010000000
VERSION     DAMJWC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40748
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.033"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            140..799
                     /gene="cprR"
                     /locus_tag="PC503_001983"
     CDS             140..799
                     /gene="cprR"
                     /locus_tag="PC503_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2527955.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1010..2068
                     /locus_tag="PC503_001984"
     CDS             1010..2068
                     /locus_tag="PC503_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2527956.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPEKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2319..4463
                     /locus_tag="PC503_001985"
     CDS             2319..4463
                     /locus_tag="PC503_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2733..2735,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HDF2527957.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4512..5345
                     /gene="fdhD"
                     /locus_tag="PC503_001986"
     CDS             4512..5345
                     /gene="fdhD"
                     /locus_tag="PC503_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2527958.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5356..5529
                     /locus_tag="PC503_001987"
     CDS             5356..5529
                     /locus_tag="PC503_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527959.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5587..6138
                     /locus_tag="PC503_001988"
     CDS             5587..6138
                     /locus_tag="PC503_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2527960.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6163..7539
                     /locus_tag="PC503_001989"
     CDS             6163..7539
                     /locus_tag="PC503_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2527961.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7539..8054
                     /locus_tag="PC503_001990"
     CDS             7539..8054
                     /locus_tag="PC503_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2527962.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8132..9415)
                     /locus_tag="PC503_001991"
     CDS             complement(8132..9415)
                     /locus_tag="PC503_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2527963.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9603..10025
                     /locus_tag="PC503_001992"
     CDS             9603..10025
                     /locus_tag="PC503_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2527964.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10127..11065
                     /locus_tag="PC503_001993"
     CDS             10127..11065
                     /locus_tag="PC503_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2527965.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11251..13275
                     /gene="ligA"
                     /locus_tag="PC503_001994"
     CDS             11251..13275
                     /gene="ligA"
                     /locus_tag="PC503_001994"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2527966.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13435..14784
                     /gene="rph"
                     /locus_tag="PC503_001995"
     CDS             13435..14784
                     /gene="rph"
                     /locus_tag="PC503_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2527967.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRTIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14784..15254
                     /locus_tag="PC503_001996"
     CDS             14784..15254
                     /locus_tag="PC503_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2527968.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15448..16734
                     /locus_tag="PC503_001997"
     CDS             15448..16734
                     /locus_tag="PC503_001997"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2527969.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16884..17468
                     /gene="clpP"
                     /locus_tag="PC503_001998"
     CDS             16884..17468
                     /gene="clpP"
                     /locus_tag="PC503_001998"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2527970.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17487..18737
                     /gene="clpX"
                     /locus_tag="PC503_001999"
     CDS             17487..18737
                     /gene="clpX"
                     /locus_tag="PC503_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2527971.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18808..19335)
                     /locus_tag="PC503_002000"
     CDS             complement(18808..19335)
                     /locus_tag="PC503_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2527972.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19323..19835)
                     /locus_tag="PC503_002001"
     CDS             complement(19323..19835)
                     /locus_tag="PC503_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2527973.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20015..22378
                     /gene="lon"
                     /locus_tag="PC503_002002"
     CDS             20015..22378
                     /gene="lon"
                     /locus_tag="PC503_002002"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2527974.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22368..22979
                     /locus_tag="PC503_002003"
     CDS             22368..22979
                     /locus_tag="PC503_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2527975.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23244..24614)
                     /locus_tag="PC503_002004"
     CDS             complement(23244..24614)
                     /locus_tag="PC503_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2527976.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24789..24904)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25192..26271
                     /locus_tag="PC503_002005"
     CDS             25192..26271
                     /locus_tag="PC503_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2527977.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26662..27342
                     /locus_tag="PC503_002006"
     CDS             26662..27342
                     /locus_tag="PC503_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2527978.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27335..28714
                     /locus_tag="PC503_002007"
     CDS             27335..28714
                     /locus_tag="PC503_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2527979.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28885..29970
                     /locus_tag="PC503_002008"
     CDS             28885..29970
                     /locus_tag="PC503_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2527980.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30024..30383
                     /locus_tag="PC503_002009"
     CDS             30024..30383
                     /locus_tag="PC503_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2527981.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30436..31308
                     /locus_tag="PC503_002010"
     CDS             30436..31308
                     /locus_tag="PC503_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2527982.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKNIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRGFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31309..31752
                     /locus_tag="PC503_002011"
     CDS             31309..31752
                     /locus_tag="PC503_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527983.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31767..32351
                     /locus_tag="PC503_002012"
     CDS             31767..32351
                     /locus_tag="PC503_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527984.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32604..33641
                     /locus_tag="PC503_002013"
     CDS             32604..33641
                     /locus_tag="PC503_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2527985.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLNGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33722..34087
                     /locus_tag="PC503_002014"
     CDS             33722..34087
                     /locus_tag="PC503_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527986.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34092..34409
                     /locus_tag="PC503_002015"
     CDS             34092..34409
                     /locus_tag="PC503_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527987.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34457..36061
                     /locus_tag="PC503_002016"
     CDS             34457..36061
                     /locus_tag="PC503_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527988.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36185..37813
                     /locus_tag="PC503_002017"
     CDS             36185..37813
                     /locus_tag="PC503_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2527989.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38078..39427
                     /locus_tag="PC503_002018"
     CDS             38078..39427
                     /locus_tag="PC503_002018"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2527990.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39583..40662
                     /locus_tag="PC503_002019"
     CDS             39583..40662
                     /locus_tag="PC503_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2527991.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
BASE COUNT        16748 a         4304 c         7338 g        12358 t
ORIGIN      
        1 tctaagatat tttatttgta aaatagtaat taattattgt aagctataat atgagagtat
       61 tatggttaat gtgaatttta aagatattat taaatatata aattagaata ctattaaacg
      121 gataaatgga ggagttatta tgtctaagat attagtagta gatgatgagt tagatatgtt
      181 aaagttgatt gaaaatgtgt tgaaaagaga tggacatgaa gtaaaggtaa ttagtgatgt
      241 agaaaaagct atgaacatgg attttaatta ttttaatcta ataatattag atgttatgat
      301 gcctaagatg gatggttttg aagtatgtaa aactataaga aataaggttg attgtccaat
      361 actgtttttg acagcaaaaa atatggaaag tgatattatg tacggtcttg gtataggtgc
      421 agatgactat ataaccaaac cttttggtgt aggagaatta agggctagga taactgctca
      481 tttaaggcga gaaagtagag aaaaaaagaa tttattaact atctcaaatg ttcaatttaa
      541 ctttttaggc aaagaagttt caattgatgg taaaaaaatt aattttacta aaagtgaata
      601 tctaatatgt gaatttctag caaaaaataa gggacaagta ttttcaaaag aaagaatata
      661 tgagtcggta tatggttttg atggagaaag tgatataagt actatcacag agcatataaa
      721 aaatatacga agcaaattaa aacaatatga tatttataca atagaaactg tatgggggat
      781 agggtataaa tgggtgtaat aagtataagt gttgtttagt gaaaatatta tatatatcta
      841 caaaatgttt gtaaaatatt aatctatata ttaaaattta atttatagat taatattttt
      901 tgtaaatgac aaaattgtaa ggtattttgt tataaaatat taagattcat agtgtatact
      961 aataatatag tatttagtat aaatcttgag caaaggatgg ttatttctaa tggatagact
     1021 aaagaatatt agaaagagtt tactacagta tacattttta tttttgttaa taggtataac
     1081 aatttaccta gtgtttaaaa cattggatat taaaatgcta tcaaatgtta tggttatggt
     1141 agataagaag tttttattca taggtgcttt ggcaataatg tgtcacataa tgcttgaagg
     1201 agtagtaatg aagataatta tagaaagcac tcacaaagtt aatattagat ttattggttt
     1261 taagctagcc attatgggat tttattataa tttaataact ccttttgctt caggaagcca
     1321 accagtacag atatatgtac ttaaaaaatg taaaatgcca cttagtaagg caagtgcagt
     1381 tgttaccaat aagtctatta tcttccaaat agtagttact ttttattgta caatacttgt
     1441 tttaatgaat tttgctatgt tagaaaaaca aatgaaaatg attatgcctc tagtgtttct
     1501 agggatagcc attaattcat ttgtcttaat tatgataata ttagttattt taaatcctga
     1561 aaaaataaaa tattttatga gaattactat aaagcattta tcaaaaatta agtttttaaa
     1621 atttttagat aataagattg aatccataga aagttttata gatgattata gtaaagcaat
     1681 aaattttttt gcaaagaata aaaaggtatt aatttcaact ataatagtaa cttttattca
     1741 attaagtgct tactttagtg tttcattttg gatatataaa gcatttaatt tacaaggtta
     1801 tagctatatt tatatactga cattacaagc atttttatat atggcaatat ctccaatacc
     1861 aacacctggg aatgtaggag ctaatgaatt agcctttttc actatattca aatcagtatt
     1921 ccctcaacct ttgatgggat atgcagtatt tttatatggt ggatttatgt actatttgat
     1981 tctgattgga agtggaatat ttactgtaat tactcactat agaatgaaaa acagaattgg
     2041 cagaaatatt gttttaagtg aaaactaaat aagtttaaag aatatatatt gagtatatta
     2101 aaaaatatgt cataagaact agaatatttt aattaaatgg ttgaaatata aagattatta
     2161 tgacatattt tttttgaaat ttaagaggaa ttgtgagaaa attgttgaat ttaatagata
     2221 gtattgcaaa atatttatga ttttgcatat tataaaaaca ctcattatct ttaagataaa
     2281 ttttacttat caggggataa atctaagggg ggaattgtat ggagaaaaaa attttaacag
     2341 tttgtccata ctgtggagct ggatgccaat tatatctagt agtaaaagat aataagatat
     2401 taagagctga accggctaat ggtagaacaa atcaagaaag tttgtgttta aaaggtcgtt
     2461 atggatggga ttttctaaat gaccctaaaa ttctaacacc taggctaaaa aagccaatga
     2521 taagaaaaca aggtgtacta gaagaggttg aatgggatga ggctataaac tatacagctt
     2581 caagactaaa tgaaattaaa gaaaaatatg gacctgattc tattatggga acaggttctg
     2641 caagaggacc tggtaatgaa gcaaactata taatgcaaaa atttatgaga gctacaatag
     2701 gaactaataa tgttgaccat tgtgctcgtg tctgacatgc accatctgta gccggtctgg
     2761 cttactcatt aggtagtggt gcaatgtcta attctatacc agagatagaa aatgcagatg
     2821 ttttatttat atttggatat aatggagcag attcacatcc aatagtggca aatagaatag
     2881 taaaagctaa aaaaaatggt gctaaattaa ttgttactga ccctagagta actgaatctg
     2941 caagaattgc tgatatacat ctacctataa aaggtggaac aaacatggtt ttagtaaatg
     3001 cttttggaaa tgtattaata gaagaaggtc tttacaataa agaatttgtt caaaatcata
     3061 cacaaggatt tgatgagtat aaagaaattg ttaaaccata tacagctaaa tatgctgaaa
     3121 agattacagg aatcccagaa gagcttataa gaaaagctat gagagaatat gcaaaaggta
     3181 aaaaagctat gatactttat ggaatgggtg tctgtcaatt tggtcaagct gttgatgtag
     3241 ttaagggact tgcatcaatt gctctactta caggtaattt tggtagagaa agcgttggaa
     3301 taggacctgt acgtggacaa aataatgttc aaggagcttg tgatatggga gctcttccta
     3361 atgtatatcc tggctatcaa aatgtaactg atgataagat aagagaaaag tttgaaaaag
     3421 cttggggggt aaaattatct cctaataatg gttatagttt aactcaagtt ccaaatttag
     3481 tactaaaaga gaaaaagctt aaagcttatt atatatttgg agaagaccca gtgcaaagtg
     3541 acccagatgc atcagaagtt agagaagcat tagatgaatt ggaatttgtc attgttcaag
     3601 atatatttat gaataagaca gcacttcatg ctgatgttat acttccagct acttcttggg
     3661 gagaacatga gggagtatat acatgtgcag atagaggatt ccaattgatg agaaaagcta
     3721 tagagccaca aggagatgta aaaccagact ggcaaattat aagcgaaatt tctacagcaa
     3781 tgggatatcc tatgaattat aaaaatacta aggaaatatg ggacgaactt agacaattat
     3841 gtccaagttt cttaggtgct acttatgaaa agatagaaac tcaaggatgc gttcaatggc
     3901 cttgtaagag tgaaagtatg gaagataaag gaactatgta tctgtatgaa ggtcaaaagt
     3961 tttctactcc taatggtaaa ggtaatttgt tcgctgctga atggagaccc cctatggaag
     4021 ttgaagatga tgaataccca tttagtttat gtactgtaag agaagttgga cactattcag
     4081 taagaacaat gactggtaat tgtagaacac ttagttcatt agaagatgaa ccaggacgtg
     4141 ttcaaataaa ttctaatgat gctgaaaaat taggaattga agatgatgaa ttagttagaa
     4201 ttagttcaag aagaggaagt gtaataacaa gagcaacagt tactgataga gttaaggaag
     4261 gtgcaacata tatgacttat cagtggtggg ttggagcttg caatgaactt acaatagcaa
     4321 atttagaccc tatatctaaa acaccagagt ataaatattg tgctgttaaa cttgaaaaac
     4381 ttgaagacca agaattagca gaaaaatgtg taagagaaga gtatcaaagt ttgaaagaca
     4441 aaatgacagc tacaaatatc taatgattta ttagatttaa gatttataaa aggcagaaag
     4501 gctaatattt tatgaacaat atatactcaa aaactaaatt acaagaaaat agtaaggata
     4561 aagtttttga aaatagttat agtctagtgg actacaaata tttaaattct tttaatgtag
     4621 aagtaagcaa aataaatgaa catgaagtat caatagataa tgaagaaata attgcagaat
     4681 atccacttag ttttatttta aatgataaat atgtaaatac atttttatgt accccatata
     4741 atttagagga acttatagta ggattcttga aaacaaaagg atacatagaa aacaaaaaaa
     4801 gcttattaaa atttgagata aatgagagtg aacgttttgc aaaagtaact attcaagaga
     4861 aacaaaaaaa tcaagatgag caaattatat ttttaaattc actagactat ataacatgtg
     4921 ctcctgtaaa gagcaatata aaaataaatt atgatacgat ttacagtata atggataaaa
     4981 atttaaattc atcagaatta tttaaaaata ctggtggggt acatagcgta tctgtattta
     5041 attttgataa aaaaatagtc acttgtgaag atgtagcaag gcataatgca atggataagg
     5101 ctattggatt ttgtgtttta aatgacataa cattaaaaga taaaattgtg gctgtaagtg
     5161 gaagaatatc attggaaatg atattaaaag cagctatgac tcaaattcct attgtagtat
     5221 caaaatcagc accgactaat ttatcaatag agctttctaa aaaattaaat ataacgctta
     5281 ttggatttgt aagaggaaga cggatgaata tttatgcaaa tccacagaga gttatcaaaa
     5341 agtgagaatg aatatatgtg tactaaaaaa gaagagcaaa gatattcaaa gtgtgaaatc
     5401 tgtggagtat taattgatga tactgataag gtgtataata acacatacaa tttgtgcaaa
     5461 aaatgtaaac gaaatataag tactgagaaa atagtgaaat atataaatat atatgatgaa
     5521 agtaagtaga catatgatga aaataactag agggttggaa atatacaaat tgaaaggtgg
     5581 gataatatga aaaataaaat aggctctttt gtaatagcag acccaaacaa atgtacaggt
     5641 tgtagagctt gtgaagtagc ttgttttaca atgcataatc agcataataa tgtgggttat
     5701 acagttggaa cagttgatat acctgttata cctagacttt acttagtaaa aggtgacaat
     5761 ttctgtatgc caatacagtg tagacattgt gaagatgctc cttgtttaaa ctcatgtcca
     5821 caaaaagcta tagttaaaga aaacaatatt atgtctgtaa atgaagaaaa gtgtatagga
     5881 tgtaaaactt gtctgctagc atgtcctttt ggagctatag acttacttcc acaatatgaa
     5941 gatggtaaag aagtagaaca agtaatttta gatgaaaata agaagatagc ttataaatgt
     6001 gacttatgta aagacaatga aaaaatagct tgtataagtg catgtcctca ggaagcatta
     6061 aaacttgtta ctccaataga tgacaaaaaa gctaagaata gacaagctgc acttagttta
     6121 ttgttaacaa ataaataaag gatacagggg taggtgacgt ttatgataat aaatatagat
     6181 aaggatttat gtactggatg tagagaatgt tcaaaggtct gtccagtaaa tgctattgaa
     6241 ggtgaagagg gaaagccaca agagataaat ttagatagat gtgttatgtg cggtcaatgt
     6301 gttcaaactt gtaaatctta tgcctcagtt atagatgaag gatttgagtt tttacaagag
     6361 aaaaaacaag aaagagagat accagagtct ataaatgaac ctatatttgc agcatacaat
     6421 gtatgtgata tagataaggt gaagaaagct ttaagtgacc caaatgtatt cactatggtc
     6481 caatgtgcac cagcagttag agttgcttta ggagaagatt ttggatatta tttaggatac
     6541 ttaggtgctg ggaaaatggc agcagcactt agagctttaa attttgatag agtctacgat
     6601 actaattttg cagcagattt aactataatg gaagaaggta gtgaattaat taaaagagtg
     6661 acagaaggtg gaactcttcc aatgtttaca tcttgttgtc cagcttgggt aaaattcatg
     6721 gaaaaaaatt atcctaaatt aactaatcat ttatcttctt gtaaatcacc tcagcagatg
     6781 ggtggtgcaa tatttaaaac ttatggtgca gagataaata atgtagatgc atcaaagata
     6841 tttagtgttt ctataatgcc atgtacatgt aaaaaatatg aatgtgatag agaagaaatg
     6901 gattctagtg gatatagaga tgtagatgta gtattaacta ctagagaact agcttattta
     6961 ataaaagaca tgggaattga ttttaaaaat ttaagagaag aaaaatttga tagtccttta
     7021 ggtagttata gtggagctgg aactatcttt ggtgttactg gtggggttat ggaagctgct
     7081 ataagaacag gatatgagct tataactgga gaaagtattc ctgatgtaga agtaaaacaa
     7141 gtaagaggag aaaatggttt tagaaagtca actattaaaa taggagactt agacttaaga
     7201 gttggagtag taagtggatt aaaaaatgta ataccagttc ttgaagactt ggaaaaagga
     7261 aaattagatg tagattttat tgaagttatg acttgtcctg ttgggtgtgt aagtggtgga
     7321 ggtcaaccaa aaattttact agaagaatat aaggaattgg cttatgaaaa tagaacaaaa
     7381 gcaacatacg tgcatgatga acatttagca attagaaaat ctcatgagaa tcctgatatt
     7441 aaaaaactgt atgatgaata tctggtagaa ccattaggag aaaaatctca tcatctatta
     7501 cacactacat attgtatagg aaaggaagtg gctaagtgat gaactatttt gttatagcag
     7561 accctgataa atgcatagga tgtagaactt gtatgatagg atgtgtagtt gcacattcag
     7621 atgaagatat tttttaccaa aatccagatg aaataaattt taatccaaaa ctttctgtca
     7681 taaagacaaa agaagtaagt gctccaatac agtgtagaca ttgtgaagat gctccttgtg
     7741 caaaggcatg tccaaatggt ggtatagtta gggttggtaa cacaataaaa ataaatgaag
     7801 aaaattgtat aggatgtaag acttgtatgt tagcatgtcc tataggtgca atagacatag
     7861 ttacattaaa agatgtagat gaaggaaagc tttgctttag agaaagaatg acagcaaata
     7921 agtgtgattt ttgtatagaa tcgccagaag ggcctgcatg tgtaaatgtt tgtccaacta
     7981 aggcatttac tatagttaag gatgaggata tagatagtaa agttaaaaat aagagaaaat
     8041 tagctatatt gtaatataaa aaagatggag ttttatttat gattaaaagc tccatctttt
     8101 ttattataat atttatatat ctaaaaatca attattgcat tagtttatct aatctttctt
     8161 tattcaattt tttcattcct atagaagtta taataagtaa agtataggca attataactg
     8221 ataaaattat aatagaccaa gaaaatctgt atccaaaatt atcaactaac aatccaaata
     8281 atgttgaacc taatgcaaat cccactgcaa aaattaattg tacgattcca tatatgctac
     8341 caaactcctt ttgaccaaag aaagagccag ttaaataagc aggaccaatc atataagcaa
     8401 atacagaaag acctttcaaa atggcaaata caaatgcaaa agtagaagat ttatctacca
     8461 atagtaatga taaagttgct ataagaacca atacaaaaga tataataagt ggctttgttt
     8521 gaccgaattt atcaaacaat aatcctccaa ataaattacc aatgagagca aataaggcaa
     8581 atgtggagcc tactgttcct attagaatag gatttagata atttctaaga taagttggat
     8641 attgtacaga taatgatgaa acatatatac caacaaatat aaatccaata gtcataatcc
     8701 aaaaatattt aattttttta gcttctttta atgtataacc ccatactgaa ggagaaattg
     8761 tatcagatgc tttctctttt ttacctttag attttacctt ttcattaata tctttaggca
     8821 tcctgagtat gaataatatt acaggtatac caactattaa tgctataatt ccaaatatta
     8881 gataagaacg actgtatcct tgagttgcta ataagcgaac tgcaagtggt tgtagaaata
     8941 tactaccaat agaaccacca gcaaaagcaa agcccaaagc ttttcctttg ctttcttcat
     9001 caaaccaagc acttattaaa acaggtattc ctatagcaga tataattgta gcgccaattt
     9061 gaacaataca tgatacagtg taaaattgcc atagttcagt acatatagaa aaagtagcaa
     9121 aagcaatact agaaattata caacctaata aatatagtat cttaatattg actttagaaa
     9181 ataatacacc tataaaaggt gatgcaattg ctgaggcaat agtaccaata gtgaatatta
     9241 gagaaaaaga agctaaacta aagccttctc cttctacaac ataacttata aattgaggct
     9301 gtatacttgc tacaatacta aatggaacag cttgtattaa catacaacca agtactataa
     9361 cccaagcatt tgaaaagttt ttaatgctaa atttattgtt tagtaatgta ttcatggtat
     9421 ctctccttta ggttatgatt tgtagatatt aatctaatta ttctaatttt atatattagt
     9481 tttggatagc ctaactattt aaatataatt tgggtattaa tataaaaatt aactataaaa
     9541 attgattatt ttaaatgtat ggggtaaatt aaagtatata aataaatgaa aggatggata
     9601 aaatgtcatt tgaaaaaata aataataata acctagataa aatacacaat aggaagtgta
     9661 ttatgcttgt aaactttaat aaaaaagaat tatcattaat taaaaatgta agtaactttg
     9721 ctggaataag agaccatatc atcttaagtg ataaaaatgg agagaatata ataagagaca
     9781 ttttagatgg aaatatatca aatgaatgtg aaaatgggat taagagtaag tctgtaatat
     9841 ttaataacac tccaagtaca caagtaaatg catttttaga agggctaaaa aaagtgagaa
     9901 taaatagacc ttttacagct atggtaacag agacatctat tgattggaca ttgaataatt
     9961 taatagaaaa tttagttcaa gaacgtaatg ctatgtcttt aggaaaaaca attgaacata
    10021 agtaaattta agatatctta tagtaatttt aactaatgta cattgagtat catattatat
    10081 tttagaatag aaaattttaa atgtgggtag atggaggaga tttgagatga aagttttatt
    10141 tacaataaat tatggaaaag aaaaatttga taaaataaga gaattaggct atgatgtcat
    10201 acattactct gaagatagta ttgaaaataa tgaggatgta aatacagcag atgtactagt
    10261 tacatacaat ccatttgaga gattagatat ttctaagatg aaaaatttac aatatataca
    10321 gacaactagt gtaggtatag accaacttcc aaaagaagag gtattgaaga gaaatattaa
    10381 gatagctaat aatagaggcg gatatagtgt acctattggt gaaagtattg tattgtatat
    10441 tttagaaata tataaaaata gtgcaaaatt ttttaaacaa caacaaaata aagaatggaa
    10501 gatggatttt tctgtatcag aattgtatgg acaaagagtt ggatttttag gaacaggtac
    10561 tatatcttca gaagcagcaa aaagattaaa agcttttggt gtagaaatat ggggtgtcaa
    10621 tactgatgga agtagtaaaa aatactttga taagtgtttt gctactgagg atatgaatat
    10681 tgtatttgaa gaatgtgata tagtagttgt agcaatgcct tctacaaaaa gtacagatgg
    10741 aatagtaaac aaagatatgt ttaaacttat gaaagatggt tctgtattta taaatgtagg
    10801 tagaggaaat acagttaatc agaaagattt agaagaatgt gtagagaaat ttagaggggt
    10861 agcattagac gtatttgaaa gtgaaccttt aaacaaggac aataagttgt gggagtgcga
    10921 aaatgtcata gtaactcctc ataattcttg ggtgtcagat aaaaacaaag agagaacatt
    10981 taatatggtt tataataatt tgaaacacta tataatggag aataaacctg tagataatgt
    11041 tgtagacata tcaagaggct attaaaaata aaaaattttg ataaaaataa aaactcttat
    11101 tagtcgtatt aaagatacta ataagagttt tttttgtaat aaatttaaag cccaaaaagt
    11161 gatatactaa aaaatatata aataggagat aattaattat agggaaattt caaaataatt
    11221 taattttaaa aatatgaaga ggtgcaaaaa gtgagcgtaa aagatgaaat taataaactt
    11281 atagagacaa taaactacca taatgaaagg tattataatc aagatagccc agaaatatca
    11341 gattatgaat acgataagtt aatgaaggag ttaatttctt tagaagaaga acatccagaa
    11401 ctaaagagaa ttgattctcc aacaaatagg gtaggaggta agccattaga taagttcaat
    11461 caaattgtac ataaaactcc tatgttgagt ttatcaaatg ctttttcaga gcaagatttg
    11521 agagattttg ataagagagt tcaagaatat gtgggagaaa atgttgaata tgttgttgaa
    11581 tttaaaatag atggtctttc tgtaggtcta acttataaca atggagagtt tgaaaaagga
    11641 gcaactagag gagatggagt tgtaggagaa gatatttctc aaaacttaat gacagtaaaa
    11701 agcatacctc ttaagataaa tgataaaaaa gaactaatag ttagaggaga agtatatata
    11761 tcaaaagata attttagaaa agtaaatgaa caacaagaag aacaagaaca gccattattt
    11821 gctaatccaa ggaatcttgc agctggttca ttgagacaat tagacccaaa actaacagca
    11881 aagagaccat tagatatatt tgtatttaat atggaaaata tagaagaata cgatttagaa
    11941 agtcacagtg aatcactaga gtacttagaa aaactaggat tttcagtaag tcagagttat
    12001 aaagtttgta aaagtataga tgaagttatt gagcatattg aatactggac agataacagg
    12061 ggtaatttag actacgaaat agatggtatg gtaataaaag taaacaatat aaaacaaaga
    12121 gacgaaatgg gatatacagc caaaagtcct agatgggcaa ttgcatataa attcccagca
    12181 gaaaagaaga aaactaaaat agtagatata atagtagaag ttgggagaac tggtacaata
    12241 acaccttcag caattcttga accagtcaga cttgcaggta ccactgtaag tagagctaca
    12301 cttcacaatg aagattatat aagagaaaaa gatataaaaa taaatgatac agtattagtt
    12361 caaaaagcag gggacataat acctcaagtt ttagaagtta taaaagaaga acgtactgga
    12421 gatgaaatag attttaaaat gccagaaaag tgtccagttt gttcagagcc aacaataaga
    12481 ttagaaggag aagctgctgt aaaatgtatc aatatgtctt gcccagccca aataagaagg
    12541 ggaattatac actttgtgtc aagggatgca atgaatatag atggattggg agaatctata
    12601 attacactgc tattaaatga aaaaattatt caagatgtat ctgatttata ttatataaaa
    12661 aaggaagatg tagtcgacct agagagaatg ggcgaaaaat ctgctgacaa tttaataaat
    12721 tcaattgaaa aatcaaaaga aaatgattta tggagactta taaatggatt aggtattaaa
    12781 tttataggag ttaaagcagc taagatactt gcatataact ttaaggattt agatgaagta
    12841 atttctgcaa ctagtgagca actagaagaa ttagaggaat ttggaagtat aatggcaaac
    12901 agcgttgtcg agttttttaa ggaagacaaa aatatgaacg ttataaacaa gttaaaaaat
    12961 gtaggagtaa atacaaaatc attggataat acaggtgaaa aagtagaaaa aatatttgaa
    13021 ggtatgaaaa tcgtattgac tggtacactt cctacattaa aaagaaatga tgcaaaagat
    13081 atgatagaaa aaagaggtgg aaaagctaca tctagtgtta gtaaatcgac aacatttgtt
    13141 ttggcaggtg aagaagctgg ttctaaactt actaaagcaa atgatttagg aattaaagtt
    13201 atagatgaag agagattttt agaattatta aagttatcat cgaaagatga agtaaaagct
    13261 gtattagaga gttaaaaagt cgcttaattt agtagaaaac tactataatt aatgatagaa
    13321 tagttcagta agctaataag attacgaaaa atgacaataa ttaatatttg acaaaattaa
    13381 aaattataaa aataaattta taaaaaataa aaaatatgag aaaggatata aaaaatgacc
    13441 agaagttatg atagaagtaa tgaacagata agacctgtaa agataactag agattataca
    13501 aagtatgcag aaggttctgt tcttatagaa atgggagaga caaaggttat atgcactgca
    13561 tcagtggaag aaaaagttcc tcctttttta agaaatagtg gtactggatg gataaatgct
    13621 gaatattcta tgctaccaag agcaacacaa caaagaaaga taagagatgc atctagggga
    13681 aaaattgatg gaagaacaca agaaatacag aggttaatag gaagaacaat aaggtctgtt
    13741 gtagacttga ataaattagg agaaagaact atttgggtag attgtgatgt gattcaggca
    13801 gatggtggaa ctagaactgc atctataaca ggggcatttg tagcagttgc agaagcaata
    13861 tataaattat ataaagcaaa gacaataaaa gagatgccaa taacaaattt tgtgtctgca
    13921 attagtgttg gtattgtaaa tggaatacac atgctagatt tatgttatga agaagattct
    13981 aaagcacagg tagatatgaa tataataatg actgataagt gtgagtttgt agaagtacag
    14041 gggacaggag aagagaaacc tttttctaga gcagatttaa atttattgtt agagttaggt
    14101 gaaaaaggga ataaagaatt aataaggctt caaagagaag ctttaggtga aatatcagat
    14161 gagatattgg gtatggatta tggtaatgaa gtagtgattg ctactaataa tgctcataag
    14221 ctagaagaaa taggtgaaat cttaaaagat tttgaatata aagtgtactc tttaaaagat
    14281 gttgatttag caggtataga gatagtagaa gatggaaaaa catttgagca taatgcgttg
    14341 ataaaagcta gaacaatagc aaaaaagact aaacttatag caatatcaga tgattctggc
    14401 ttagaagtag atgctttagg caaaaaacct ggtgtttatt cagctagata tgcaggagaa
    14461 catgcaacag atgaagaaaa tagaaaaaaa ctgttaaaag ctatgcaaaa tgtaccaatg
    14521 agcaaaagaa atgcaagatt cgtctctgca atagcagtag tttttcctga tggaaaagaa
    14581 tttgtagtaa gaggaatttg tgaaggaatg ataggatttg aagaaaaagg taaaaatggt
    14641 tttggatatg atagcttatt tatagtaaaa ggatatgata agacttttgg tgaaatacct
    14701 agtgttataa aaaattcaat cagtcataga gcaaacgcac taaaacttat gaaacaagag
    14761 tttataaaaa gggtagtgaa gtaatgaaaa taggcatagt aagcgacaca catatgatga
    14821 ttaaaaatat ggaaaaaaca ataccatatt tgaaagaatg tgacctaata attcatgcag
    14881 gagataactt tactgattca agatatattc atagcatgac taatgtaggt attattgcag
    14941 ttaaaggtaa ttgtgacttt gatgctgttg aggaagaagt tgtctttgaa gtggcaaata
    15001 aaaccatatt cttatgccat ggagataagt atggtgtaaa atatggaact aatatgttag
    15061 aaaaaaaggc aactgaagtt gatgctgata tagttatatt tggccatacc cataccccat
    15121 ttagagaaat taaagatggt gtactttaca taaatcctgg aagcacttca cttccaagag
    15181 gagtatcgta taaaagtttt gtcattatgg atatagaaga agatgacata aaaattgaag
    15241 aaatacgcat ataaaggtgt atttatctaa aaaaatggca aaaaacgctc aaaaaattaa
    15301 attttatcaa ataagtacaa cgatattaat ggaacacttg taaataaaaa aacttatgtg
    15361 atataattaa gtggttgaat tataaataga atgaattata ataccgttat cgggtattac
    15421 ataaatatca ctaggaggat tagaaggatg aaagcagaac taattaaaaa agagggtaat
    15481 aaagttactt taaaaataac agtagataac aataaatttg aagcagcagt aaataaggct
    15541 tataataaaa gcagaaataa atacaatata cctggattta gaaaaggtaa agctccaaga
    15601 attgttatag agactcaata cggaaaaggt atattctaca atgatgctat agaaatatta
    15661 ttcccagaag tttatccaga agctatcaag gaattagaca tagacccaat agacaatcca
    15721 gatttagata tagaagaaat aagtaaagac aatgggttgg ttatggttct taatgtagaa
    15781 gttaaaccag agtttgaatt aggaaactac aagggtatag aaatagctaa ggttgagaat
    15841 actgtaagtg acgaaaatgt tgatgctaaa ctacaagaaa tggttgaaaa aaatgccaga
    15901 ttagtaagtg tagaagacaa agctttagaa gatggagata cagctataat agacttcgaa
    15961 ggttttgaaa atggtgtagc ttttgatggt ggtaaaggtg aaaattataa cttagttata
    16021 ggttcaaaca catttatacc aggatttgaa gaacaattag taggtaaaaa agctggtgaa
    16081 gaagtagaag ttaatgttac tttcccagaa gaatatcact cacaagattt agctggaaaa
    16141 ccagttgtat ttaatgtaaa aataaatgat gtaaaagtaa aagaattatc tgcacttgat
    16201 gatgaatttg ctaaagatac tagtgaattt gattctttag atgaattaaa agcagatgta
    16261 agagctaagt tagaagaaga agctaaaaat agagcagatg cagaaactag aaattcagta
    16321 gtagaaaaag ttgctgaaaa tacagaaata gaaataccag aagttatgat acaacatcaa
    16381 atagataata tgttaaatga acttaactac caattacaat atcaaggatt tggattacaa
    16441 caattactag agatgactgg tagaactatg gaagaattaa gagaagagag aaaagaagat
    16501 gctaaaaaat tagttaagtc ttctttagta ttagaagcaa taactaaagc tgaaggaatt
    16561 gaagcaacag aagaagaatt taaggctgag ttagaaaaaa tggcttctgc ttacaatatg
    16621 gaagtagaaa aaatagaagc ttctttaaga gatgctgaca aagaagatat aaaaggtcaa
    16681 ataaaaataa gaaaaacaat agatttatta gttgataatg caacaatagc ttaataaaat
    16741 aaacgctaac taatatagtt gacgttatga aatgtttagt atataatgat gtgcaaatat
    16801 aatttagtta aatgcgtata ataatttaca gtagcttaaa aaaagctact gtaaattata
    16861 tagaataaag ggggtatgaa accatggcat tagtacctgt agttgttgaa caaacaggaa
    16921 gaggagaaag atcttatgat attttttcta gactattaaa agacagaata atcttcttag
    16981 gagatcaagt taacgatgcc acagcagggc ttatagtagc acagctatta tttttagaag
    17041 ctgaagaccc agacaaagat atacatttat atataaattc tccaggagga agtataactt
    17101 ctggaatggc tatatatgat actatgcaat acatcaaacc agatgtaagt actatatgta
    17161 taggtatggc tgcttctatg ggagcattct tgttggcagc aggagcaaaa ggaaaaagac
    17221 tagcactacc aaatagtgaa ataatgatac atcaaccatt aggtggagct caaggtcaag
    17281 caacagatat agaaattcat gcaaagagaa ttttaaaaat aaaagaaact ttaaatgaga
    17341 tattatctga aagaactggt cagccattag aaaaaattaa aatggatact gaacgtgata
    17401 acttcatgag tgcactagaa gccaaagaat atggtttaat agatgaagta tttacaaaga
    17461 gaccgtagat agagagaggt gttaatatgt ctaaatatga agaaaaacga caattaaagt
    17521 gttcattctg cggtaaaaat caagatcaag taagaagatt aattgcaggt ccaaatgtat
    17581 atatttgtga cgagtgtgtt gaactttgtg acgaaattat tcaggaagaa atagaagata
    17641 ctatagatga agatactaca tctttaccaa aaccaaagga aatgatggag attctaaatg
    17701 attatgtaat aggtcaagaa aaagctaaaa aagctttatc agttgcggtt tataatcatt
    17761 ataagagaat atacagtaaa aaatctagta gtaaggatat agaaattcaa aagagtaata
    17821 tacttttatt aggacctaca ggttctggaa agacattact tgctcaaact ctagcaagaa
    17881 ctctaaatgt accttttgca atggcagatg ctacatcatt gactgaagct ggatatgttg
    17941 gagaagacgt tgaaaatata cttttaaaac ttattcaagc tgctgatttt gatatagaaa
    18001 aagctgaaag aggtataata tatatagatg agatagataa gattgcaaga aaatctgaaa
    18061 acccatctat aactagagat gttagtggtg aaggtgttca acaagcactt ctaaaaatat
    18121 tagaaggtac tgttgcaaat gttccaccac aaggaggaag aaaacatcct catcaagaat
    18181 ttttaaagat agatactact aatgtattat ttatattagg tggagctttt gatggattag
    18241 agaagataat tcaaaaacgt ggtggagata aaacactagg ttttggagct aaaatagaaa
    18301 gtaaaaaaga attagattta gggaagctgt atgaaaaagt acttccagag gatttattaa
    18361 aatatggtat aataccagag tttataggaa gaataccagt tttagctact ttagagttgt
    18421 tggatgaaga tgcattaatg cagatattac aggaacctaa aaatgctcta gtaaaacagt
    18481 ataaaaagtt attggagtta gatgatgttg agctagaatt tgaagaaggt gctcttcgtg
    18541 caatcgctaa aaaggccata gaaagaaata caggagctag aggacttaga agtatagttg
    18601 aaagcgtaat gatggaaact atgtttgaag taccatctag agataatata aagaaggtta
    18661 tagtaacaga gaaatctgtg aacgaagact cagtaaatcc tatcatagta cttaaggatc
    18721 aagaggaaag tgcataagat gatgaaaagg agctttaaaa gctccttttt ttatgttaat
    18781 atgctaaata taaaataggt atcattatta taaaaatgtg agtaatatac ctagaatacc
    18841 aaagacgaat acaattgcaa tggaaccaat ttttccttta tataaaagat aaaatgatgc
    18901 tataaatgca attattccat ataaatccca attaacttct ttggcagatg aaaaagctgc
    18961 tgataatatg aatcctagag taattggtct aagaactgtc aataagtttt ctaccttttt
    19021 attattttta aatttagaaa ataactttga tataatagtt agacctatta atgcaaaaat
    19081 tgtaacacca atagttgcag ctagagaacc aaagaagcca gcagtcttaa atcctacaaa
    19141 tgtagcacta tttattgcta caggacctgg tgtagattgt gatatagcaa gtaaatccaa
    19201 aaactcttga ttagttataa agtgatattt agatataaat tcttgctgga taaatggtag
    19261 catggcataa ccgccaccaa aactaaatgc ccctatttta aggaatatta agaagagtag
    19321 tattatttct gacatagact atatacacct cctccaatta ttaaataaat agggcttata
    19381 ttgaatacac caacagataa aactgctata attaatagta gtatgttagt tttagacttt
    19441 ggtagtttct tgaacatgct cgtaaaagaa tacaatataa gagctattac aacaggcgca
    19501 actcctttaa aaaatccatc taaaatttta gatgatgaat ttttaaagta tagatacgat
    19561 aagactaaga ctatacaaaa tgatggtaaa gcagagccta aggtacatat aagaactcct
    19621 ggtataccat aaagtttata tcctaataat acagatatat taactgccag tactccagga
    19681 taactttgag ctatggataa ataatcaata aattcttcct gctctaaaag tttttgtttg
    19741 tttacaagtt catcttgtat aagaggaacc atagcgtatc caccaccaaa tgtaaacgca
    19801 ccaattttta aaaaggttaa aaacaatttc aacataatag aaacctccaa aagataaata
    19861 acatctaagt atactaatat taatattata tcataataaa aagataatat agtatgatag
    19921 tattctaaga atttatcatt aatgttgaaa attaacttgt tcaaatatat aatattaaaa
    19981 gcaaagcaat tagactagaa aaggagtaat gttgatggaa caaaattata ctaaaataga
    20041 tcatgaatta ccattaattc ctctaagagg attagctata tttccatata tgatattaaa
    20101 ttttgatata ggtagagaga tatctcttaa agctttagac caagctatga tggatgaaga
    20161 acttatattt ttaacttctc agaaagaagc agaggtagat gagccaggag aagaggattt
    20221 ttatcatgtg ggaacaatct gtaaagttaa gcaaatgata aaattaccag gagatacagt
    20281 tcgtgttttg gttgaaggtg tatcaagggg tagagtaaag aaaatagaac aagaagatgg
    20341 gtatttcaga gcagtaatag aagaaatagt atttgatagt gataatttgg atagtgaaac
    20401 agaagttgaa attgaagcat ttgtaagaaa tgtatttgat gcctttgaag agtatataaa
    20461 tattggaaat agggtatcac cagaaatatt aatatcttta gctgatatag aagatgtaga
    20521 tagatttata gatacgatag ctgcaaacat atatctaaaa tcaagccaaa aacaagaaat
    20581 attagaagaa tttgatatta gaaaaagact tgaacttatt tattctatat tattagagga
    20641 aatagatata ttaaaaatag aaaagaaaat aactttaaga gtaaaaaaac agatgaataa
    20701 ggttcaaaaa gaatattatc ttagagaaca attaaaagct atacagaaag aattaggtga
    20761 agaagaagat ataaactctg aagcagatga gtatagagaa aagcttaaaa aaataaaagc
    20821 acctaagaca actaaagaga aaatagaaaa agagatagat aaattttcaa aaatatcttc
    20881 tatgtctcca gatgtatctg taagtagaaa ctatttagat actatattct cattgccatg
    20941 gaataaagag acaaaagata aattagatat aactaaggca aaagatatat tagatgaaga
    21001 ccattatgga ttagaaaaag ttaaggagag aatactagag tatctagcta taagaactct
    21061 tgctaagtca cttaaagggc ctataatatg tctagttggt cctccaggaa caggaaagac
    21121 atctatagta aaatcaatcg ccagagcatt aaatagaaaa tttgtaagaa tatctttggg
    21181 tggagttaga gatgaagcag aaataagagg tcatagaaga acttatgtag gttcaattcc
    21241 aggaagaata attaatgggg taaaagaagc ccaaacaaaa aatcctgtat tcttatttga
    21301 tgagatagat aagatggcag cagattataa aggtgaccca gcttcagcaa tgctagaagt
    21361 attagaccca gagcaaaata aggattttgt ggaccattac ttagaaatac cttttgattt
    21421 gtcaaaaata ctatttgtta caacagcaaa tagtctaagt aatataccaa gaccattatt
    21481 agatagaatg gaagtaatag aagtatctgg atatatagaa gaagaaaaat taaatatagc
    21541 aaaaaaatac ctacttccaa aacaaattaa agaacatgct ttaaaagaaa actttataaa
    21601 aatagatgat gaaactttaa gaagtataat caaccattat acaagagaag ctggtgtaag
    21661 aacactagaa agaactattg gtaagatttg tagaaaggtt gccaaaaaat acgttgaaga
    21721 cccaactctt gaagaggttg ttataaataa gtctgaccta gagacatatc ttggaaaaga
    21781 catgtttaag tatcaacttg cagaagttaa ccctcaaata ggattagtaa atggtcttgc
    21841 atggacagaa gttggtggag ttacacttga agtagaagta aacgtactta aaggtaaagg
    21901 agaaattgta ttaactggaa aattaggaga tgttatgaag gaatctgcga agacaggtat
    21961 ctcttatata aggtcaatag tggacaagtt tgatatagac cctgaatttt ataagacgaa
    22021 tgatattcat atacacattc cagaaggtgc tgttccaaaa gatggaccat cagctggtat
    22081 aactatggct cttgcagtaa tctcagcact tactaaaaga cctgtgcctg gaaatatagc
    22141 aatgacagga gagataactt taagaggtag agtcttagca gtaggaggag ttaaagaaaa
    22201 gttattagca gctcatagag ctggtataac aaaagtatta attcctaaag aatgtgaagc
    22261 tgatttagat gaaataccag aaaatgtaaa agaaaaaatg gagtttgtgc ttgtagaaca
    22321 tatggatgaa gtattagaac aagctttatt aaagagtggt gaaaataatg aaaattagaa
    22381 gttcagagat aactatgagt gctgtgaata aatcacagta tccagcagaa ggaatcccag
    22441 agatagcatt ggctggtagg tcaaatgttg gaaaatcatc aataataaat acattgctta
    22501 acagaagaaa cttcgctaga accagtcaaa caccaggaaa aactagaact ataaattttt
    22561 atctaataaa taatgaattt tattttgtag accttccagg ctatggatat gcaaagatag
    22621 ctaagtctga aaaagaaaag tggggaggta taatggaacg atatctagaa agtagacaag
    22681 agttatgttc tatattccta cttgtagata ttagacatga gcctacagca gatgataagc
    22741 ttatgtatga atggataaag cactttggat ataactgtgt agttattgca actaaggcag
    22801 ataaaatatc tagaggacaa tatcaaaaac acataagtat aataagaaaa aaattgcaaa
    22861 tggaaagtag tgaaaaagta attcctgttt cttcactaaa aaagactggt gttgaagaat
    22921 tatgggaaga gattgtaaat caatacaatc aacatggata tgaaataaca gtagattaaa
    22981 tttaaaatgt taaatattga catgagattt atttgaataa taaatgtaat aatagttagt
    23041 tttaattata ttaatattaa agcaaaatat aggatgcctt aaaatagttt taatgaactt
    23101 tttttggcat ccttattgtt tataaacaat aaatatcagt aattttgtta aatactaata
    23161 aattttagta aggtatggga aaattagtat aaattagttc aactaaaaaa ttattgactt
    23221 atgtagtcag caataaatag catttaagaa atagatttat ctgtttttct cataaagaaa
    23281 acagttagta taagccctat aaaacatact gatgctgcaa tccaataaga ctgattgcta
    23341 gctataacat aggctgatgt gtgactttta aacttttgat tgtatgtaag actttgtgca
    23401 aaaaaactac taaaaaatgc tgttccaaga gcaaatgata aattacgaat agttgcaaga
    23461 aaactgcctc cgtatccctg tttttgagga ggaacatctg ctaaaatact actattgttt
    23521 ggtgaactaa atgctcctag cccaagtcca aaaataacta aacatacaat taaaagatac
    23581 aatggagaat ctgcttttaa aagtgccatt ccaactagtg agatggtcat aaatgaaaaa
    23641 gatgctgtta gaatgttttt tgcaccgtgt ttatcagaaa gtgaacctgc aataggtgct
    23701 ataagtacca taataagtgg atgtacagtc attacataac cagccatcat aggagataaa
    23761 ttttttaatt gttctaaata aaatggaagt agaaaagata ctgccatttg aggaaaataa
    23821 caagctactc caatgatatt gcctacagta aagtttctat ttttaaatag aggtaggtca
    23881 ataaagcttt gttcaaattt tacttctctt aatgccaaca ataagaagat tataagtgct
    23941 gttataccta aatacaatct tgtattaccc ttctcattca ttgcaagtaa tataagcgta
    24001 gtgcaagatg cgaaaagtag aagacctgga atatcaaagc tcttgttttg ttcatccaaa
    24061 acaggtttag gtagaaattt aatgccaaga aagactgcta taataccaat aggtatattg
    24121 ataataaaaa tagaaggcca tccaaaatgt tctaaaatta tacctccaat tacaggacca
    24181 ctcatatttc ctataccaac tacagctcca gtgattccta tagcttttcc tttttcattt
    24241 gctggaaatg cattggaaac tataccaagc ccagtagcca ttaaaatact tgctccaact
    24301 gcctgaaaga ttcttgaaga aattaatgtt gataaattgt ttgacatact acacagaaaa
    24361 gaacctattg taaatataaa aaatcctaat gtgtatagac gatttgaacc tactttatcg
    24421 ccaagttttc cgaaaaataa catagtagct gttacaacaa gcatataagc tgttacaacc
    24481 cactgaattt gtgacatgtt aattttaaag tcagcagcaa ttgtaggatt tgcgatattt
    24541 agtatacttc catcaagagt agacataaat acaccaatac agatgataat caatactatc
    24601 catttttgtt tcatgataac actccaatct taatagattt tataagtacg atataattgt
    24661 aaaataaaca acaaaaaaag cacctgtata ttaggtacct tgaatgtgtc taatttcatg
    24721 aataaatacg gtagttgaag gatttgtata gattactcat gtaaaattac ataaaggtac
    24781 tcatatacta ttttcttcta ccatccagat tttactgtcg gctttggaat atgaccaaat
    24841 tatgccataa ggctcgcggg cttttaccgc cgatagggaa tttcacccgt ttatgaagaa
    24901 aaacagatgt attttgtaat attattttaa cataaaatta taatggaaac aattggattt
    24961 aagtaatatc cagctgtatt acaatacaaa tatttcaata tggacactta aattgtattt
    25021 atagatagaa taaggaacag tatgagaatc tataataatt agataaaatt aacctgttat
    25081 tagtattaga tggtaagttt taaatttatc aaaatcagaa agctgtaata aaattcttat
    25141 aatatgaata tcttaattaa gagatattgt aaattatgag gaggcgctaa tatggaagga
    25201 aaggtaaaga aggcattccc gggtggaaat acatcacaag gctcatattc tttttttgac
    25261 tatataattc ctgaaaatgt aaaaagagtt ttttgtttaa agggtggacc tggagtagga
    25321 aaatcctcac ttatgaaaaa aatttataaa gagtttttgc atagaggata tgatattgat
    25381 ttatatcatt gtccttctga cccaagttcg ttggatggtt tagttataaa gaaattaggc
    25441 gtggtactta tggatgcaac tgccccacat actatggacc caaagctacc tggagctttg
    25501 gatgagataa ttaatttagg tgattactgg aatacagaag aattagaaaa gaataaacaa
    25561 gaaatatcag tttatgataa agatattagt aattcattta aaagagcatt taagttttta
    25621 aaatcagcag aaccaatctt tagagacata gaagaaaaat attctgattg tatggattat
    25681 ggaaaagtaa atttggtcac agaagaattt ataaaaaggt tatttgatgg agttaaaagc
    25741 acaggaaatc taaaaagaga aaagcattta tttggttcag ctataactcc tgtagggtgt
    25801 ttagattata cagaaaacat tttaaaagat gtaaagaaag tctattattt agatggagaa
    25861 ataggaactg ggaaaactac attattaaac aaagtatata agaaagctat tgaaaaaggt
    25921 ttaaatgtag aagtttatca ttatccactt attccagaga aaattgaaac tgtactatta
    25981 actgatttag atataggcat aactataagt acgactttta aagaagaaga tacaattgat
    26041 ttaaatcagt ttttaaatag agaaaaacta cttaaatatg aagaagatat taaatttgat
    26101 gaaaaagttt tagatgattt aatttgttgg gcagtactaa atcttaagag agccaagtct
    26161 aaacatgata ttatagaaag ttactatagt cctaatatga gatttgatga agtagggaaa
    26221 ttaagagata agttaattaa aagaatttta aaatatgagg aaaacttata aacgcatatg
    26281 tttaaaatta acgttagtaa taatataatt tttagtaaat tggtgtagct ttgaggctat
    26341 gccattttac tttttttgct aaaaaatgat attaataatc tccaaagcca ttatttgttt
    26401 ttcataatta ttatttcctt tcctaattta tgttttttta taatatcaca acaatgttta
    26461 ttgaaagttt atataatttt aagaacatct aaaaatgcat acttgatatt ggtaaattag
    26521 tgataggagt tcaatgtatg atattatata ctaaagatga attttaatat ataactttga
    26581 tataataagc atatgtaaat gtttaatatt taattaaaga aaattatcat ataaaaataa
    26641 atttgtaagg agcaatacag tatgaaaaaa caatatgtgt ttataatact agcaagtact
    26701 attttaggta tacttgttgg aaccatattt agagattata gcaatgaaga aacagtttat
    26761 acaagcaaag acaagtcaat aagaaaagaa ataaaaatga caagaaaatc tataaaagaa
    26821 ttaaccaaag agaaagacaa gttagataaa gaaattaatt caatgaaaca aaatcaaaaa
    26881 aattctgaag aaatatcaga aatagaaaca cttagagata gtctatcata ttcagatgta
    26941 aagggtagtg ggataatatt aagtatagat gctatagatg aaaaaacagg gaatatagct
    27001 aatagtatag actataataa gattcttgta aaagttataa atgaattaaa agtaaacgga
    27061 ggaaaataca tagaaataaa tggtcaaaga attaatcaat attcagaagt tgtacttgca
    27121 ggaagccata taaatataaa tggagttcct gtagcacaac catatgaaat aaagtgcatt
    27181 ggagataagg agaaactatc taattatgta gataaaggta gtaaatattt agatagcata
    27241 caaaccaatt atccaatgaa aataagcata aaaactgaag aaaatatctc tatgaaaaaa
    27301 atgaatatac ctaataaatt aaagtatata aagggtgatt aagattatat tagaggaaag
    27361 cagtttgcca atgttaatac cagaaaaact tgcaaaaaaa tataatgtat ttccagttga
    27421 gtttcaagat gataatttag ttgtagaaat agaagatgag gatatttatg ctctacagga
    27481 cttgagatta gctacaggta aagaaattat attgaagaag gagaaaaaag aacttataag
    27541 tgaaaagatt gaaaaatatt ataatagctt tgaacttgat gaggattatg caaaaaaatt
    27601 atttgaaaat cttttagaaa aagctataaa agaaaacgca agtgatatac atatagaacc
    27661 atttaaagaa catttaatag tgagaatgag ggtagatgga gaactaaagg aagtatcaaa
    27721 gtttttagtt gatgtctatc catcattgtc tacggttata aaattaaagg catcaatgga
    27781 tataacagaa aaaaggcttc ctcaggatgg tagggtggat ataaagttag gtggaaattt
    27841 aattgacatt agagtttcat caataccaac tgtctatggt gaaaaaatag ttttgaggat
    27901 acttaataga gatacttttt taaaagacaa attagaactt ggtttttcag aggaagctat
    27961 aaaatctata aatcgtataa taaataaaag agcaggaata ttattagtga caggtcctac
    28021 aggtagtgga aagactacaa cagtatattc cttattaaat gatttaaaag gaataaataa
    28081 aaatattatg actatagaaa atcctgtaga gtataagatg gatggcataa gtcagattca
    28141 agtaaattca aaagtagggt tgagctttga tgtaggtctt agagcgatat taagacaaga
    28201 cccagatata ataatggtcg gagaaataag agatgcagaa acagctaaga tagcagtaag
    28261 agcagctata acaggtcatt tagttataag tactttacat actaatgatg cagtatcttc
    28321 catagctaga ttactagaaa tgcaaatacc accatatctt ttaaatgcct ctcttatagg
    28381 tgttatatct caaaagttgg ttagaaaagt ctgcaatcat tgtagccatg agattatgat
    28441 aaaagataat tttagtggag atgtaaatac taaggtagct gtagggtgtg aaaaatgtaa
    28501 tgataaagga tactttggaa gaacagcaat ttatgaaatc ttagaaatta atgatgatat
    28561 aaagacatgt ataagaaata tggaggattc tagtactatt aaagatgtag cacaaaataa
    28621 tggaatgata acatttgaag atagttgtaa aagactaata aatgaaaaaa taacgacatt
    28681 agaagagtgt ttagtagtaa atgaaatgat ttaactgaat tgtatagtta aacttcgttt
    28741 ggtcagttgt ctttatttaa tctattttaa ttaagatgtt tgagtataaa ttatatttaa
    28801 gtgaaataaa attaaatgca ttaaattaga aaatattaag tttatttaat tgtaattaat
    28861 ataatttgga aggtattata gtacatgaga ttatctaaaa atatatttta taatttagaa
    28921 aagttttatt tagtattaaa tagaatcagt gataaagaaa ttagagtaat ttgcaaagag
    28981 ataggcatat tgctggaatc tggatgtgaa attacaaaaa tatttgaaat cattgagagt
    29041 cagtcaagta aaaaagtaaa gaacttgctt agtatagtat caaatcatat tcaaaaaggt
    29101 aactcaatag cagaatcatt tcaaataaca ggtatatttt ctaaattctt tataagtatg
    29161 ataaaagcag gagaaactag tggaaactta gatataataa tgagtgattt atctaattat
    29221 tatgataaag aatacaaatt aaaaatgaaa ataataacta tttcaatata tccaataata
    29281 cttataatat tatctatctt atcaatgttg tttatattcg tatttgtaat acctaatttt
    29341 caggtggttt ttaccaacaa tggaattgaa ccacctttaa taactagagt tttaatggga
    29401 atatctacag tggttacaaa taacttagct tatataatat ttagttttat attgttttca
    29461 ataggaagca tttatttctt tataacaaat gataatataa aaaaattgat taattcgtta
    29521 aaattcaaaa taccttttat aaaaaaaatt aatcagttag tagctacaac aagattttca
    29581 agggcattgt ccgttttaat tagcagtgga atacaaattg tggaagctat agatatgtca
    29641 gctagtgtta tagacaacga atttatttat gaaaggttaa agatttctaa taattatata
    29701 aaaaaaggaa atagcatagg taaatctttg aatttagcaa atatttttcc aaaattattt
    29761 atttcaatgg caaatacagg agaagaaagt gggaaactag ataaaagtct aaatgtaata
    29821 aataaatttt atgaaaatga attaaataac aaaatagagc aaataatgaa atttatagaa
    29881 cctatgctaa ttgtatttat gggattaatt attggtactt ttattttagc aatggttgtt
    29941 cctatgtttg atgcaattac taatttttag agagaaaaat aaattttatt agatgaaact
    30001 tttgaaaagg agagaatatt taattgataa atttgataaa taaaaaacga aaaggattta
    30061 cacttgttga aatgattgta gtagtaacta ttttaggcgt tatatctagt atagcattag
    30121 ttaagtatag taaggttcaa gaaagtgcca aattaaatgc agactatacg aatgctgcta
    30181 atatagtaac cgcagctagc atggcaatta atgatgatga aaagacaata gactctctaa
    30241 gtgtagagac attgaaggaa aagggatacc taaatactgt tccagttcct cagagtacat
    30301 caggtaaatt cgaacttgtc ataaatgata gcggaacaga tataagcgta aatataaatt
    30361 ctaagcaatt ttatccaaaa taatatttta tattgattgc tgtaagtttt aaaattattt
    30421 ttatttaaga aggagatggc tataattaaa aaaattctaa acttagaaat aaatgatgat
    30481 tatataaggc ttgtattttt aagaaaaagt cataaaaaag tttttataga taaatcaatt
    30541 ataaaagaga ttaactttga tataaaaaat gatagtaatt cgattgagaa gattaaatat
    30601 atagaagatg tagttagatt tgtaaaagag gagattggta aatcaaaaat attatataaa
    30661 aatttatact ttaacattca aattcaggat atagtcatta gaaatgttga agttctaaat
    30721 actaagaaaa aaagagacat attaagcatg attgaatttg aaataacaca atacattcca
    30781 ataaacataa ataactattc aataaaatat aaagttataa attctaaaaa tgataaattg
    30841 aatatacaag taattctttt cccaaagaat attattcaat taattaagaa catttcagaa
    30901 aatctaaata tgaatccaaa gactataaat ataaattttg atatattaca aaagcttata
    30961 aacttaaatt taatagagaa tttttcagaa gaaggggtat ttatagaatg taaaaaaagt
    31021 cagttaatta taaatataac aaaagataaa aaaataagag aaacatactt gctatcaaaa
    31081 gagggaaaat catatgagtt cataaaaaga ttattaaggg gttttaagta tgtttattac
    31141 tatggtatag aaaattgttt tattgaagaa tactttaaat atacagataa atctattgaa
    31201 gtaaatccat taagattaaa agataaagta aaagtagaaa ataattttga tgcagattta
    31261 gaagacaata ggataaatta tataaatagt ataggaatga ttatttaagt gaaagtggat
    31321 aaaacaataa attttcttaa tggatttaaa aaaactaaac catgtaataa aatctataaa
    31381 ataataatag tcttaatttt aacgtgtatt ttatttaaat catttatgta tgtgaaatct
    31441 ataaatgaac ttgaagatta tataagtcaa aataagctag tggataaatc aaagaacact
    31501 ttaccaacaa cagataaaac tagagagaaa ttttctaaaa taaaacttaa tgaaataaaa
    31561 aaaatatatg aaacaattgg aataaatagt attactaaaa tatcaataga taaaaataag
    31621 ctagagatgg aaggtgtgtg tagtgattta gatgttttaa acaatttaag gaaaataaag
    31681 tacataaaat attattacat agacagtatt gtaagagatg gagaatatta tagatttaga
    31741 ataaaaagtt agatgggtga ttatttttga gattaaataa tagagaaaaa aatctactta
    31801 aaatattgtt aatattagtt attatattgg caagtgatat agcagtaagt tatttggaag
    31861 aaaacctaac tagtttgaag aatgaaaagc aaaatataat aaataaaata aataatcaag
    31921 ataattatca aataaaggat aataagcata tagatgataa atatatagaa agtgttgaat
    31981 taaataaaaa tgaagaattg aaaaataatt ttaataactc atttttagat aaaaaaacaa
    32041 ataaagatat agtgttatta gtagaaaatg aactgagaga tattgtgaat gtagaatata
    32101 ttaatcaaga aagtagttta gataatcaca ataaaaaaca agttaattta gaaataaaag
    32161 ttaatggaga acttgcaaat gtgttgaaac ttgaaggtgt aatgaagaag ttaagactaa
    32221 ataataaact tgaaaagata gaaattaaca aattaaaagt caataatttt gatgttcaaa
    32281 atattccaaa tgaatataaa caagaaaaag acaatattgt tgaatgtaaa atgacagtta
    32341 gagtcatata acaaaaaaga atagataaag taaaaaacta ttatcaatta ataaaatttt
    32401 atagaggaat tagttttacg ataattcatt tctacaagag ggattgttga tgattttatc
    32461 gaaatcctaa ttaaagttaa tatattgtac caaaatataa gtgaatttaa tagaatattt
    32521 acttatacta tagattgatt aataaaaaaa tggtataata acaaattgta ctttaattta
    32581 ataataaggg agtggaagtc atattgttag ggagaaatga gctatgccct tgtggaagtg
    32641 gcaaaaaata caagaaatgt tgtttaaata aagatattgt ttcagaaaga gcatgcagaa
    32701 aaactgaact ttcacaaaaa caatatacag atttatattc aaagttatat gattattcaa
    32761 gacaggataa gtttaaagaa gaatgtgaaa aagctaaaga aatgttttat ataatgcaaa
    32821 atgatagtgt aaatgaaaaa tttgaaagat tttttaatac ttatttaata caagaccaca
    32881 taatggaaaa taaaaaggtt atgacagttg gttttcttga agaaaatggt gcaaacctaa
    32941 gtcaatcaga agtatcaata ttaaaaagta tgtttgaatc atacgtaagt atttatgagg
    33001 taaaagaagt ttctgctgga aaaatagtat taaaggactg tttaaatgga aatgaacttt
    33061 gtacagaaga tgtaaaactt ctgagaagtt ttaaaatcgg aagttgtatg atagctagaa
    33121 tagttgatat tgaaggaact aacatattga tagatataac tataagtata tcaaatgagg
    33181 ttaaagatat aattttaaag gatattatga atctattcaa tcaatatcaa gatgtataca
    33241 aagatatgaa gtcgttctta atttatcata cacatatact atacaagtat atacaacagc
    33301 ttttagaccc aagtatagct gaatatttaa agagagaaag agataaaaac gatacaaaag
    33361 ttaattcaga aaatgaatta gctgaagaag aatgtaaagt tttagatact cttaaagaaa
    33421 atgtagaaaa agaaaatata gatgcatgta tagagttttg gaatgaatat aagaaaaatc
    33481 atgaaaatat aaaaggagct gaaaatggtt gggcagctgc tgttgaatac tatgttaaaa
    33541 aagaagcagg acaacctata actcaagttc aaatatcaaa gaaatacgat ataagctcta
    33601 gtacactagg aaagagatac aaggatttaa aaatatctta attaattata aaaagcttta
    33661 agtcatagat aaagaatcta tagtataata tatgtataat gtttagaaag aggtattaat
    33721 aatgagtctt agtttaggaa atgcaattgc tgtatcaacg aactttataa aatctaaccc
    33781 agctgtacct gtgtacaacg gagaagaaat atatgcagtt atttatcata tagaaatagg
    33841 atataataat ggtgtatcac ctgataccaa acaatatata ataatagact ataaagagtt
    33901 tgatttatct atggataaaa aaaatgaact aataaatatt gctaaagagt actgtaaatc
    33961 taaaggtatt gtagaaaacg aaaaccttga aataaacctt ttagacaatg aagaagcaga
    34021 gaacttctta gaaaaggtgt ttaataatat gaaggttata agaggtctta taactaaaaa
    34081 aggataaata aatggactat ataggaatag aaaatataac accttatgaa aatacatatg
    34141 aatttagtgt atatgaatat gatgatgaaa tcaccttagg tagtgaaaag ttatatgtat
    34201 gtgaattaag ggttgtattg attaaagtta attctctgta tgttgaaaga ttgcataaat
    34261 cagttgaagc aatggtctta gtaaaaaact tgaaaaaaga tttagataaa acacttgttg
    34321 taaacaaaat aaagaatttt gtgctagatg agatttgggt agaaaatcta gtaaaagaga
    34381 atatagaagt tatatttgta gaaagctagg aataacccta gcttttttat attacaatct
    34441 aagagaggaa aacaatatgt taagagtatc taatgtaaaa cttggaattg ataaagatat
    34501 atctttatta aaagatgtta tacttaagaa gctaaaaata aaagaaaaaa acttagtcaa
    34561 atatagtata tataaagaat ctatagatgc tagaaaaaaa ggaaaaatgg aatttgttta
    34621 ttctgtagat gtagaagtta aagatgaaaa taaaatactt aactcaaaaa taaaagatgt
    34681 aacaaaaata aaggaaatca gatacgtaaa tgtacctgtg ggtgataaaa aattaaagaa
    34741 taatcctttg gtaattggta gtggaccagc tggcttgttt gcaggtctgc ttttagctca
    34801 aatgggttat gaaccaatca tacttgaaag aggtcttgat gtagacagta gaaccaaaga
    34861 tataagtgat ttttggacaa ctagaaaatt aaaaaataat tcaaacgttc aatttggaga
    34921 aggtggagca ggaacttttt cggatggtaa acttacaact agaataaaag atatacgatg
    34981 tagaaaagta ttagaagagt tagttcagtt tggagcacca gatgaaatat tatactcaca
    35041 taagccacat gttggaacag atatattaaa aaatgtagtt aaaaatataa gaaatgaaat
    35101 aataagttta ggtggtcaag ttagatttaa ttcaaaagta acagatatag ttgtatcaaa
    35161 tgattctata caatctgtaa taataaatga tactgaaaaa atagatacag atacaattat
    35221 attagctgtt ggacatagtg caagagatac ttatgaaatg ttgtattcaa gaggtataaa
    35281 aatagttcaa aaaccttttg caataggagc tagagttgaa catccacaag atttaataaa
    35341 taaagcacag tacaaggatt tttataatca tcctaggtta ggagctgcag attatagact
    35401 tatagagcat gtttcaaatg gaagaacagc atatactttt tgtatgtgtc caggaggtag
    35461 tgtcatagca tctgcatcaa atgattttga aatagttaca aatggtatga gtgaacatgc
    35521 aagagataaa ataaatgcaa atagtgcatt tttagtaaat gtaacgccag aagattttaa
    35581 gagtgataat ccactagcag gtgttcattt ccagcagaag tatgaaaaat tagcttttga
    35641 attaggtgga aaaaattata atgcaccagt tcagcttgtt ggagatttta taaacaataa
    35701 gacttctttg aatttaggaa gtgttgagcc atcatataga ccaggatata cacttacaaa
    35761 tttaagtgaa tgtttgccta gcttcgtaac agagactatg agagaagcgt ttatatctct
    35821 tgataaaaaa ttgaatgggt ttgcaatgta tgatgctgtt ttgacgggag tagaaactag
    35881 gtcatcatca ccaataagaa tagtaagaga tgaaaatact ttagaatcag tgagtattaa
    35941 gaatctatat ccatgtggtg aaggtgctgg atatgcaggt ggtatagtta cagcagcagt
    36001 tgatggtata aaatgtgcag aaaaaataat acaaaaatac accaataata caaaaattta
    36061 acataaactt aatgattttt taatatttaa catgaattta acattatcac tcctataatt
    36121 tgataaaata caataggtta taaaattttt agatacagta atctctttac aaggaggaaa
    36181 taatttgaac attataataa gtctaatggg tggattaggt ctgttcttat atggtatgaa
    36241 ccttatggga gaaggtcttc aaaaatctgc tgggacaaag ctaaaaaaga taataaaact
    36301 acttactagt aacctattta tgggagtttt ggtaggtaca ggagttacag cagtaataca
    36361 aagttcaagt gctactactg taatggttgt tggtttcgta aatgcaggaa taatgacttt
    36421 aaaacaggca ataggagtta taatgggtgc taatataggg actactgtta cagcccaatt
    36481 ggtatctttc gacttaactg gtatggcccc agtagcatta ggtgtaggta ttatacttta
    36541 tttatttgga aataagccta gaataaaaaa tatagccgaa atacttatag gttttggtat
    36601 attatttaca ggtatggatt ttatgaagat ggcagtggag ccactaagag actatcaagg
    36661 atttactgac ttacttgtta catttggtag atatccacta cttggattat tattgggatt
    36721 tgggattaca gcaataatac aaagttcaag tgcatctatg ggtatgttgg ttgcactggc
    36781 agcagaaggt ctagtgccat tatcagcagc actgccaatt ctttatggcc aaaatattgg
    36841 tacatgtgta acttcactgt tatcaagtat tggtgctaac aaaaatgcac gaagagcagc
    36901 tatgatgcat ctaatcttca atgttttagg aacggtgata ttcttaatat tcttgaataa
    36961 accagtagta agcatggtta caagttggga cccaagcaat gttgcaagac aaatagccaa
    37021 tacacataca ttgtttaata taatatctgt attgatactt ttaccattta caaatcttat
    37081 tataaaacta gctataaagc ttgttcctga tagagcaggt gatatagatg aagatgaaac
    37141 taaaactatt aaatatatag atgatagaat gatagaaact ccttctatag ctcttgcaaa
    37201 tacgataaaa gaagcacttc gtatgggtga gaaggcgaag gaaagcctaa atgcatctat
    37261 ggaagcttta gtagaacatt caactgaaaa aatagataag acatataggc gagagagatt
    37321 aatcaatgat ttacagaaag ctattttaaa ttatttactt aaactttcaa aagcaccttt
    37381 agatgatgat tcaagagaag ttgtggatac tttgtttaat acagtcaatg atatagaaag
    37441 aattggtgac cacgctaaaa atatagctga attatcgcaa gttgcaatag attcaaatat
    37501 ttctttctca gaagaaggac aatctgaact tgatgttatg tataatagag ttgtttcagc
    37561 atatacttat gcattagaat caatgagaac tgataatgtt gatttagctt gtaaggttat
    37621 aaaaattgaa gaacaagttg atataatgga gaaatcttgt agagctaatc acatgtatag
    37681 attgaacaat aatctatgta gtatagaaaa tggagttatt tatttagacg taataagtaa
    37741 tttagagaga atatctgacc atgctgtcaa tatagcacaa caagttatag caaagagatt
    37801 aggaaatgat taaaaataat taatttaaaa taatataaaa tttaaaatag aggataaata
    37861 aaagagaaac tttaaatgat acgtttagag tttctttttt tgtaaattta tttgactaaa
    37921 atttttaaat ttatacatag ttatagcatt tagaagaatc gatttcctga taataaatga
    37981 tgagatatgt atgattttgt ggcaaacttt taaaaaaaac acctatattt tgtgttataa
    38041 tctctttaaa acgaatatgc tgaaaagagg gatttaaatg ggaaaaataa attttgatta
    38101 tagtaaagct acagagtttt tttgtcaaaa cgaaatagat gtcatgcaac catatgtaga
    38161 tgttgcgcac gacatgttac ataataaaac tggtttagga aatacttttt taggatggat
    38221 agaccttcct aaaaattatg ataaagaaga gtttgacaga ataaaaaaat ctgctgataa
    38281 gataaaatca gactcagatg ttcttttggt aataggtata ggaggctctt atttaggttc
    38341 gagagctgct atagatatgg taagtcattc ttttaggaat ggacttaaaa aagagcaaag
    38401 aaaggctcca gaagtatatt ttgtagggca taatataagc tcaacatata ttatggattt
    38461 attagatata attgaaggaa aggatatttc tgtaaatgta atatctaaat caggaactac
    38521 tacagaacca gctctggctt ttagaatatt taaagattac ttagagaaaa agtatggtaa
    38581 ggaagaagca agaaagagaa tttatgcaac aacagatgca agtaaaggtg cacttagaca
    38641 gttagctaca gaagaaggat atgagacttt tgtaatacca gatgatgtag gtggtcgttt
    38701 ttctgtattg acagcagttg ggttacttcc tattgctgct gctggacttg atattgatgc
    38761 tatgatgaaa ggcgcaaatg atgctagaga agcatttcaa aatcctgact taaaaagtaa
    38821 tgatagttat agatatgctg ttgctagaac aattttacat agaaaaggaa aagatgtaga
    38881 gttattagtg aactatgaac ctcaactaca ttatgtaagt gagtggtgga aacagcttta
    38941 tggagaaagt gaaggaaaag aaaataaagg tttattccct gcttctgtag atttctcaac
    39001 agatttacat tctatgggtc aatacataca agatggaaaa aggcttttat ttgagacagt
    39061 acttaatgtt gaaaactgta agagaaatat aactataagt tcagaggaag tagacttaga
    39121 tggtttaaac tatttagcag gtaagactgt agattttgta aatcataaag cttttgaagg
    39181 aactctattg gctcatacag atggaaaagt acctaattta gtaataaata tacctcaact
    39241 agatgagtat aattttggat atttagttta tttctttgag aaggcttgtg gaataagtgg
    39301 atatttattg ggagttaatc catttgacca accaggagta gaagcttaca agaaaaatat
    39361 gtttgcttta ctaggcaaac caggttatga aaaagaaaag gaagagctag aaaaaagact
    39421 taaataattt taaatagtta aggtttaatt aagattaaaa taatataatg aaatcatcga
    39481 aaaggagttt actcaaaata gatgatttca ttttttttat gaaaaattgg gaaaaatata
    39541 ttttgataat ttatattata ttaagatagg gagtggtatg agatgtcaag aagaaagaaa
    39601 gggataagtt tagtaatatt agttgctata ataagttcaa tacttagtag ttttctaaca
    39661 ataattttag ttaaggacaa tttagtaagt aaatctacag gaagttctac gccgatagtt
    39721 gtaaatgatg atggtaagag tcaaaatatt tatcaagcag ttgcagaaaa agctacgcca
    39781 tctgttgtag gtattacaac aactagtgtt gatactagta atatgtttgc aataccaact
    39841 gaaacacaag gtgtaggaac tggaatcata gttgattcaa atggatatat acttactaat
    39901 tctcatgtta tatcagatgg tcaagctaca agtgtaaatg tattattcaa tgatggttca
    39961 acaacttcag gtaaagtagt atggtttgac caacaacttg atttagctat agttaaggtt
    40021 gataaaactg gactaacacc agcagaattt gctgatagtg acaaagtaaa agttggagat
    40081 atatcaatag caataggtaa tcctcttgga ttagattttc aaaaaacagt tactcaaggg
    40141 ataataagtg gattagatag aactatacaa acagaaaaaa ctaatatgac tggtttatta
    40201 caaactgatg caagtataaa tgcaggaaat agtggaggac cattgttaaa tcaaaaaggt
    40261 caagtaattg gtataaacac agcaaaagct tctcaagcag aaggattagg atttgcaata
    40321 ccaatcaata cagctaagag tatagttgaa gaagtaatca aaaatggaaa atatgaaaaa
    40381 gtaactttag gcataaaagg tacagatgta tcaaattatg aagcagcaac aggtacaaaa
    40441 ttaagtactg ataaaggtgt ttatgttgca gaagtaatat ctggttcatc agcagaaaaa
    40501 gctggagtaa aggtagggga tattataact aaagtaggag atacagatat aacaggtatg
    40561 aatgatttaa ataaaaagtt gtatactttc tcaaaaggtg ctagtacaaa aataacagta
    40621 aatagaggcg gaaaagcagt aacaataaat gtgaatttct aaatatgacc agaaagatag
    40681 agactacatg gtaaagtgta gtctctattt ttatttaatt tttatagtat atacatctaa
    40741 attaatta
//
LOCUS       DAMJWC010000034        40108 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMJWC010000034 DAMJWC010000000
VERSION     DAMJWC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.034"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..196)
                     /locus_tag="PC503_002020"
     CDS             complement(<1..196)
                     /locus_tag="PC503_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2527992.1"
                     /translation="MFFSLFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSILDVAVLI
                     GFNSQNYYSIIFKKFNNFTPI"
     gene            489..680
                     /locus_tag="PC503_002021"
     CDS             489..680
                     /locus_tag="PC503_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527993.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(769..1581)
                     /locus_tag="PC503_002022"
     CDS             complement(769..1581)
                     /locus_tag="PC503_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF2527994.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            2003..3154
                     /locus_tag="PC503_002023"
     CDS             2003..3154
                     /locus_tag="PC503_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2527995.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVISDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            3272..3910
                     /locus_tag="PC503_002024"
     CDS             3272..3910
                     /locus_tag="PC503_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2527996.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3911..4933
                     /locus_tag="PC503_002025"
     CDS             3911..4933
                     /locus_tag="PC503_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDF2527997.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4923..5543
                     /locus_tag="PC503_002026"
     CDS             4923..5543
                     /locus_tag="PC503_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2527998.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5667..6353)
                     /locus_tag="PC503_002027"
     CDS             complement(5667..6353)
                     /locus_tag="PC503_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF2527999.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQNKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6367..6912)
                     /locus_tag="PC503_002028"
     CDS             complement(6367..6912)
                     /locus_tag="PC503_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528000.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            7140..8387
                     /locus_tag="PC503_002029"
     CDS             7140..8387
                     /locus_tag="PC503_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2528001.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLTFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8474..10468
                     /locus_tag="PC503_002030"
     CDS             8474..10468
                     /locus_tag="PC503_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2528002.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10468..11790
                     /locus_tag="PC503_002031"
     CDS             10468..11790
                     /locus_tag="PC503_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2528003.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            12069..13355
                     /locus_tag="PC503_002032"
     CDS             12069..13355
                     /locus_tag="PC503_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2528004.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13441..14748
                     /gene="grdB"
                     /locus_tag="PC503_002033"
     CDS             13441..14748
                     /gene="grdB"
                     /locus_tag="PC503_002033"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:14488..14490,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2528005.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            15025..15756
                     /locus_tag="PC503_002034"
     CDS             15025..15756
                     /locus_tag="PC503_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528006.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            15758..17116
                     /locus_tag="PC503_002035"
     CDS             15758..17116
                     /locus_tag="PC503_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2528007.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            17155..17640
                     /locus_tag="PC503_002036"
     CDS             17155..17640
                     /locus_tag="PC503_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528008.1"
                     /translation="MYLKRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKALQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(18295..18519)
                     /locus_tag="PC503_002037"
     CDS             complement(18295..18519)
                     /locus_tag="PC503_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2528009.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(18616..19869)
                     /locus_tag="PC503_002038"
     CDS             complement(18616..19869)
                     /locus_tag="PC503_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF2528010.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            20129..21118
                     /locus_tag="PC503_002039"
     CDS             20129..21118
                     /locus_tag="PC503_002039"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF2528011.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            21190..21930
                     /locus_tag="PC503_002040"
     CDS             21190..21930
                     /locus_tag="PC503_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF2528012.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPSLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            22130..23281
                     /locus_tag="PC503_002041"
     CDS             22130..23281
                     /locus_tag="PC503_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2528013.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            23306..24061
                     /locus_tag="PC503_002042"
     CDS             23306..24061
                     /locus_tag="PC503_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF2528014.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            24253..26640
                     /locus_tag="PC503_002043"
     CDS             24253..26640
                     /locus_tag="PC503_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF2528015.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(26871..27104)
                     /locus_tag="PC503_002044"
     CDS             complement(26871..27104)
                     /locus_tag="PC503_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2528016.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            27393..27983
                     /locus_tag="PC503_002045"
     CDS             27393..27983
                     /locus_tag="PC503_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528017.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            28097..28942
                     /locus_tag="PC503_002046"
     CDS             28097..28942
                     /locus_tag="PC503_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528018.1"
                     /translation="MIKVDDLSFSYTERDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            28939..29622
                     /locus_tag="PC503_002047"
     CDS             28939..29622
                     /locus_tag="PC503_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528019.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            29619..30335
                     /locus_tag="PC503_002048"
     CDS             29619..30335
                     /locus_tag="PC503_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528020.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            30432..30695
                     /locus_tag="PC503_002049"
     CDS             30432..30695
                     /locus_tag="PC503_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528021.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            30667..31122
                     /gene="def"
                     /locus_tag="PC503_002050"
     CDS             30667..31122
                     /gene="def"
                     /locus_tag="PC503_002050"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2528022.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            31174..31635
                     /locus_tag="PC503_002051"
     CDS             31174..31635
                     /locus_tag="PC503_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF2528023.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            31685..32587
                     /locus_tag="PC503_002052"
     CDS             31685..32587
                     /locus_tag="PC503_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2528024.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSEGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            32957..33769
                     /locus_tag="PC503_002053"
     CDS             32957..33769
                     /locus_tag="PC503_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2528025.1"
                     /translation="MYLERPELYKQSEINFWDDEYISEQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVNYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            34818..35579
                     /locus_tag="PC503_002054"
     CDS             34818..35579
                     /locus_tag="PC503_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2528026.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            35644..36426
                     /locus_tag="PC503_002055"
     CDS             35644..36426
                     /locus_tag="PC503_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2528027.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKCKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            36693..37112
                     /locus_tag="PC503_002056"
     CDS             36693..37112
                     /locus_tag="PC503_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF2528028.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(37215..37481)
                     /locus_tag="PC503_002057"
     CDS             complement(37215..37481)
                     /locus_tag="PC503_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF2528029.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            37708..38409
                     /locus_tag="PC503_002058"
     CDS             37708..38409
                     /locus_tag="PC503_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528030.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            38491..39099
                     /locus_tag="PC503_002059"
     CDS             38491..39099
                     /locus_tag="PC503_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2528031.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            39423..39887
                     /locus_tag="PC503_002060"
     CDS             39423..39887
                     /locus_tag="PC503_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HDF2528032.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTYETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
BASE COUNT        16056 a         4084 c         6597 g        13371 t
ORIGIN      
        1 caattggtgt aaagttatta aactttttaa aaattatact atagtaattt tgactattga
       61 atccaattag tacagcaacg tctaaaatag acaagtcttt ttttaatata tactttttgc
      121 ttttttcaac tctaacttta cttaaaaaat tagtaaaagt atatccactt tttttcttaa
      181 ataaagaaaa aaacaacttt tattaagttg taattcatta catatattac ttactgttat
      241 atcttctgag taatttttgt gaatataatc tatagttttc tttaagtttt ctttacataa
      301 aactaagagt tggtctatgt ttcattttat caaggcatat ttattaaaaa atcaatctct
      361 atttgttaaa ataatttatg aatgatgtta gaaactgtaa tatattggat ataatataat
      421 aaacagataa actctgtatt aagaggatat atagtttatc ttaattatag gggaagtgag
      481 gatatattat ggaaagatta atggaactca tagaaagaaa atttttaaag gatgtagaac
      541 ttttagaatt agaagacata gaaaatgtaa tagaatgcaa aatgacacag ccatataatg
      601 ctcattataa tgaatattta gtaaaagtaa aaaatggaga tgaagtagaa gaatattttg
      661 tgtatttaaa acatagataa acataaaaga ggtttatatt tatttgtatg attataaaat
      721 aaatacaagc ctcttttttt gataaatata aaattataaa atttttattt atttaatttt
      781 ttcaacaaca ttagtcaata ttgaatctaa atcatcacta atttctgtaa ctccattatg
      841 agtaatatct ataatttctt tagtcatagg aagttctcct aaaagctcta agtctaaatc
      901 atctaaaaac ttttcagtag attctccttc aaataacttg atttttttag aacaatcagg
      961 acattggata taactcatat tttcaataac tccaaggaca tttatgttca tttttttagc
     1021 catattaaca gcttttgata caatcataga taccaaatct tgaggtactg aaaccataac
     1081 tattccactt ataggaatag attgcataac tgttaaggca acatctccag taccaggagg
     1141 catatctatt aataaatagt ctaattcttc ccaaagaaca tcagtataaa attgctttac
     1201 aacccctcca agtaaaggtc ctctccaaac aacaggttca ttttcatcat ctatcataag
     1261 gtttatagac attactttta tgttatttga gttttctaca gggtaaatat aagagccatc
     1321 agaataagct tttacatttt ttacacccat aagtctagga atacttggtc cagttatatc
     1381 tgagtctaat ataccaacct tatatcccat tttgtttagc ttattagcaa gtaaagcagt
     1441 tacagttgat tttccaactc cacccttccc actcataaca ccaattattt ttccaaattt
     1501 attgttaggg ttattttcaa tagaacaatt tgattgacta ttacaatttc cctttgatgg
     1561 acatgaatta caatctgcca tatctattac ctccaaactt taatatttat tagattattt
     1621 gtaacctaca tatactattt tagtacaatt gaaccataaa gtcattattt aaaagcaact
     1681 tagaagattt tctattgatt tattcataga ctatagcaaa aagaatacaa taaaaaaatt
     1741 ataacattct tgaaaaagtg attatttcaa tttagttata gaacttagtc atataaatat
     1801 atagaaaata ttttaatatg ttatacataa cgggttattt tataagttta actataaatt
     1861 aggtttatat tttataaaaa tttgctaaaa aaaacaatta aaaattgtaa agaaaaaaga
     1921 tataattaga actgtagtaa taaatgtttt attatagata atagagtttt aagtatctta
     1981 aataatattt ggaggaatat gaatggaatt aagaccaaga agtgcaaaat tagaagaatt
     2041 tgataaagta atagaattaa taaactatgt atttagaata tcaagaaatc ataaaccaac
     2101 tatgatggaa gaatttcctc ttttactaag taaaaataat atagaaaata tgattataat
     2161 atcagaagat gataaagtga tttctgatgt aaactatcta attcaggatg tatctattca
     2221 aggaaacaga ttgaaggttg cagctatagg tggagtatgt actcatccag attatgaaaa
     2281 gagaggctat tcatctaaga tattggataa agtagaagaa aaaatgtttt atgatggtgt
     2341 agatattgta attatatcag gaacaagaag tctatacagt agaagaaatt gtagtttggt
     2401 aaagagtttt tataaatata caataaaacc tgaagatgta aaaatagcat atgaaatagt
     2461 tgaatttgat gaaactaatt ttgaaaaaga taatgattta gataaaatga ttgaactata
     2521 taatcaaaat agtactagat ttataagaac gagagatgag tttcaaaaac tattgcatgc
     2581 agcaactatt gcctggggac caattggtta caagaaggta tttataaagg aaaataataa
     2641 tataatagga tatttgataa taagaacaat aaaaaaagaa gattctactg taggagaagt
     2701 tgctgaaata gggttaaact ctgtaaatgt tgaaaatata ttgaaatatg ttgcaaataa
     2761 atttggatta gaatatttaa attataaagt acatgtgaaa aatcttaaag accagttgaa
     2821 atgtaatggg acaaaatctt tggattatca acaaggaact atgaaaataa taaattttac
     2881 taagttgtgt gatagtttaa gaagttattt tagtcaatat gtagattttg aattactaaa
     2941 atacatggaa tttaaacaag ttgaaaataa atatattatt aaatacaaag aagaagaact
     3001 tgtaatagaa aatttggata agcttaataa actgtttttt gaaaaaaatg aggaacagta
     3061 caatgaattt aaacatctaa aaaatatata tgaatttgct acaaaggcat ttcctgtaga
     3121 ttttccatgg actgcaaatt taaattatca atagttttag atgatattaa ataaaattga
     3181 ttgataccta gagttagtcc ttgttaaata agagaaatta ttggatattg aaaaagcaat
     3241 tttgtaagta attagaaagg atgagtatta tatggacata cttgatgata tagcagaatg
     3301 tatattaaat atgggtgtag ataatataga gaatttagta aaaattgcta tagataaaaa
     3361 tattgatgtg gaagatattt atgaatatgg tttaaacaaa ggtatgatag gagctttaga
     3421 taagtttgag aataaggaat actatctttc agaagttata gtatgcacag atgcattaaa
     3481 taaaggtatt aatcttttga agggaactgg aaaagtaaag aaaaaatcaa agggagtaat
     3541 tctgatgtct gtagtagaag gagatactca tgagatagga aaaaatattg taaaagtaat
     3601 ggtagaagcc actggatata aggttattga cttaggtgta aatagaaaaa gtgaagatat
     3661 aatagaagaa gctataaaaa acaatgtaga tataataggc ttatcttcaa tgatgacaac
     3721 tacaatggaa aatatgaaat cggttataga cgaacttaat atgattgaga tagataaaag
     3781 accaaaagta ataattggtg gaggacctgt aagtatggag tttgcagaag aaataggagc
     3841 agatggatac agttcaaatg ctccaaaagc agttaaatta ataaataaac ttataggagg
     3901 tgaagtttaa atgttttcag atatgacttt acttcagtat ataaatagtg aagatagagg
     3961 tttttttctg cctgatatgg gtacaaatgg attgttctta ataaataaaa aggcatatga
     4021 agtatatgat agtgtagatt tgcaattaga attagcaaag actatggaca agtattttga
     4081 atcagatttt atatactcat tctgtgatgg gattacattt tgtgaaactc tgggtttaga
     4141 gacattaaga ccagattatg attttccaag tgtattgaca catactataa ctgacagaga
     4201 taaattaaga aaattagatg ttccagaccc ttatacgagt ggacgtatgc cactcaatat
     4261 agagagctta tcagttatat caaaaagtat taaaaaacca ctatatgaat cgatacaagg
     4321 tccatttaca cttgcaggtc aattagctgg agctactcaa cttttaagat gtataataac
     4381 tgataaaaaa tttgtagaag aattattgga atttacaact gaattggtaa gaagatatgc
     4441 tgtagctgca aataaagcag gagcaaaata tatttcaata gcagagccaa catcagtaac
     4501 cctaagtaaa gatagatttg atgaatttat agtaaaaaat ttaaataaaa tctacaatga
     4561 acttgattgt tggaaaggta tgcatatatg tggagacacc agagaattat tagataatat
     4621 gctaagttgt aatatagatg cagtaagttt agaccaaatt ttagactatg aagaaattgc
     4681 tccaatgatt cctagagata tagttttgat tggtaattta gacccaataa aacttcttgg
     4741 acgttctaag ccagataaga ttagaagaga gacgctaaaa ttgttaaaga agatgagaag
     4801 atatgataac tttttatgtg attttggctg taactgctta aataccactc cagtagaaaa
     4861 tttacaagca gctataaagg caggaagaat tagttataaa gaattagata ggattgatat
     4921 tgatgaatta taatagtaat aaaaataaat atcttttaaa ggatataaat ttagatgata
     4981 tttttataga taagaatatt gtgctaaagt ttttggggta tggaaataga aaagctccag
     5041 atacaattag taaaatcgtt gaaagagaaa taagaaatat aaatgatatt ttagatatca
     5101 agatatatat aagtgaagtt gatattaata aaacacctaa agaatgtaaa aaagcatttg
     5161 ctgtactata tacaataggg gataaaattg atattaagat gaatgactat atggaaaatt
     5221 gcaatatgat ggcagggcta gcattggata aaataggtat agtatgttta gattatatta
     5281 atgagaaaat aaaaatgtat ttaaaaggaa agtatgatag tctcaaaata tcgcatgaaa
     5341 tatatccagg agataaagat tttgaagtag agagacaaaa ggatatttat aactatgtaa
     5401 aaaataaata taatagtata gaaatagaaa ttaatgatta tcatcaacta tcccccataa
     5461 aaagtgttgc aatgcttatt ttaatggggg atgaagaaaa tttagaatca agatgtagta
     5521 agtgtcctag aaaatgcttt tagttaattt tcaagactaa gatttgtttt gtgtataaat
     5581 tgcaataatt tttttggtca ttttatgtat aaactaaaaa aattattgca aagtaatatt
     5641 ctatttaatt tgaacagact tacaaactat agtagtttct ttaattcaat aagtgtattt
     5701 atttcataag ttggtatatg attagtataa tttatactgt tattggaatt taaccaacaa
     5761 gtatctattc ctgaatttat tccacctaag acatcagagg ttaagctatc cccaattatt
     5821 aaggcagaag atttatcatg acaattaaac tttttgagag cgtatttaaa tatttcagga
     5881 tttggttttg atattttcaa ctcttcagat acaaccattc catcaatata tccttttatt
     5941 tttgaatttt caagtctttt attttgaact gcagaaattc catttgttat tataacaata
     6001 gtatactttt ttttaagata ttgtaatata tcgattgcac ctggaattaa aaatgtacat
     6061 tcacctaaaa aatttaagta cattttgcta agagtttcag aatcaacatc caaagatatt
     6121 ttatttgcaa aaagttcaaa tctaagtaat ttaagttcat tcaaagttat aatatttttt
     6181 tcaaggtcga gccaaagctt atcacttata tttctatatg actctatata attctcaaaa
     6241 ttaaattcta aatcaaactc agatagaagt tttttaaaag catgtgattc acttttctta
     6301 aaatcaaata aagtatcatc tgcatcaaaa aatataaatt tatatgtctt catggttttt
     6361 actcctttac aagatgactg caaaaattac tttactttca ctatttgagt cattttgcca
     6421 tttatgtttt gttcctaaag gaacttttac actatctcct ttggacaaag taaattcatc
     6481 atcatccata aaaagtttaa cttctccctc caaaacatat gcaatttcat ctccattatg
     6541 agtaatccta tcaacacaag aagaagtgtt tggagctaaa tccataattg caaattctaa
     6601 attaccacta gagtctggaa ttaaaatctc atatataact tctttgcttc caggtaaaat
     6661 aacttttttt ctattatcat gtcttactat caagtttttt ttatctactt cagatacaaa
     6721 aaatgtaaat aaaggaacat ttagagaaga ggctatagat tttaatgaat ttacagatgg
     6781 attagcaaga cctcgttcta tttggctcaa taatgatggt gtaacatcag ctagttttgc
     6841 taaatctcga atacttaagt tttgtttttt tcgaacttca gctatttttt cccctaaatt
     6901 taaatcattc atataaatat cctctctttt taatttaaaa aatattaact taaaataatc
     6961 aagtaaaatg attatgtagt atgaaattat tataacatat agaattaggt tttgaaaaaa
     7021 ctatgttcaa tataattaaa taaattaaaa tataattgac aaagtggata cagaatactt
     7081 aaaatatatt taaataaaat taagcaaaag atagttaatt tatgatagga ggggatatta
     7141 tgcaaataac gacttttgga gctatatttg gtttattaat agcaattatt ttaattataa
     7201 aaaaatttca agctgtatat agtttaatgt taggagcatt tattggagga ttagttggag
     7261 gagcaaatat aacacaaact gtagatttta tggcaaatgg agctatgaat atatcaccat
     7321 caattcttag agctttggca tcaggtgtat tagctggaag tttaataaaa acaggggcag
     7381 tagataaaat atcagaacag attgtaaaaa tatttggtga aaagagggct ttattttcga
     7441 ttgccatttc aactatggta cttgctggag taggtgtaaa tttggatgta tctataataa
     7501 ctgtagcacc tataggatta tatataggta gaaaattaaa ttattctaaa ttgtcaatac
     7561 tattagctat gttgggaggg ggtaaagcag gtaatataat atcaccaaat ccaaatacta
     7621 tagcagtagc agataatttt tctgtcaatc tctctagtgt tatgatggca aatataattc
     7681 cagcaattat tggagttgtt attacagtta ttttagcaag tatattaata aataaaggaa
     7741 ataaagtaca atcatatgaa attttagagc aaagagaaga tttaccaagt ttatttaaat
     7801 cattatgtgg tccaattata gctatatttc tattgttttt aggaaatgta tctcctatag
     7861 ttatagaccc aatgatagcc cttccaatag gaggaatcgt aactctaatt gtcacaggaa
     7921 acttgaacaa ttcaagagaa tatttaactt ttggattatc taagatgcaa ggggtatgca
     7981 tattattact tggaacaggg actatcgcag gaattataca gatgtctgaa ttacaacaga
     8041 gtacaatagg tgctttacaa tttttaaata tgccacaatt tttattggca ccagtttcgg
     8101 gtatacttat gtcattagca acagcatcat caacagctgg tgctactata gcatcatcta
     8161 cttttcatga tgctataata aatggtgggc tatcaccgat ttcaggtgca tcaatagtaa
     8221 atgctgggtc tagtgtattc gagcaattac cacatggctc actatttcat actagtgcag
     8281 gtagtataaa catggatata ggtgaaagat ttaagttaat tccatatgaa gcattgatag
     8341 gaatagtaat gactataatt tcaacatcta ttcaattagt tttataataa atataaatat
     8401 ttaatgaaaa aagtaggatt ttgttattaa atattgaact tattatagta aaaaagaaga
     8461 ttggagtttt aaagtgaata aaaaaaagat tgttattata gggattattt attcattttt
     8521 agtagtattt tcacttacaa atatgtatgt aaatatggag tataatctaa atgtatttga
     8581 atatattaag aagtcacttc catttacaga agaagaaaaa aagtggttag aaaaacacaa
     8641 gaatttgatt tacagctctg accaaagttc acctcctttg agatataaag gtaaggaaga
     8701 tggacagtat aagggaatta ttgttgattt aataaattct ctgtcaattc aaattggtag
     8761 agatttttat tttaaaccaa ataattggtg gaaagaatct ttcgtaaatt caatagatga
     8821 tagtataaag ttttttgact tgattccatc aaaagaaagg gcaaataaat ttatatttac
     8881 tgacccaata tacactttga gtgcaaatat attgaaagat aaaaagtccc aagatataaa
     8941 tagttacatg gatttaaagg ggaaaacagt agcaattcca gaaggtgatt attctataaa
     9001 ttttttaaag caaaaaattc aagatataaa cattttattg actccagata taaagactgg
     9061 agtcaaccat ttaatgtctg gaaaagtaga cgcagttgtt ggtgatgaac cagtattgcg
     9121 atactatata aataattatg gactttcaaa taaatacagt gttttaagta atcctatata
     9181 tactaaaaaa gcagttcttg ctgtacctaa acaatatgaa gagctggtta gtattttaaa
     9241 taaaggcatt tttaaacttc agaaaaatgg agtgtataaa gatttaaaga aaaaatggta
     9301 ttctacgtat aatgaagttg atgatatatt gtatgagcga ggaattgtgc ctagtattta
     9361 tctttttata ggtataattt taatatcaat ttatgttttt tatagctata catatttgtt
     9421 aaagatagaa atcaaaagga aaacagaaca ggtaatagaa aataaaaaaa ctttagaggc
     9481 aacttttaat agtattacag atataataat gcttgtagat gaaaataaca atatagtaga
     9541 atcgaacaaa gtactatatg actttatggg tgaaatgagt tataagatag cagatttgat
     9601 tagcatgata aaaggtgtta ttgaaaatac cttctctgaa aatactaata aaactagtga
     9661 aatagaaata cacaataaaa ttttaaagat aaacactttt cctgtagagt ataaaaaaaa
     9721 taatactgag tatatagtag ttcttattaa agatataact aatgataaaa tagtagaggc
     9781 gaaattactt agagaaaaca aaatgatatc tatagggcaa ttagcttctg gggtagcaca
     9841 tgagataaga aatcctttgg gtataataag aaataattgc tatctcttaa aagataacgt
     9901 tacaatggaa gaagtaaatg attgtgttaa atcaatagaa agtaatgtag atagggcaag
     9961 taatataata accaacttgt taaatttcgc aagaatatca gatgataatt tagaacatat
    10021 aaatataaaa aattttattg aaaatatagt gaaacttcaa tataaaatgt tacagttaaa
    10081 gaatgttgaa ataaaaattg actgtgaaca taatttaata tgctatataa atggagaatc
    10141 gttaaaacat gtatttataa atttaatttc taattcaata gatgcaatac atcaagatgg
    10201 aaaaattatt atatactgtt atgaaaaaaa tcattgttta tttatagatt ttaaagataa
    10261 tggtgaagga ataaaagaag atgtcctaaa ggacatattt aatcccttct atacaacaaa
    10321 accaattggt gagggaactg gtttaggttt atatattact tataatgaga ttaaaaagaa
    10381 taatggagat ataagtgttg aaagtaaatt gggggttgga acttgttttc atataaaaat
    10441 tccattaaat aaagaggtga ctatataatg aaaatactat tagttgatga tgagctagaa
    10501 tatggagtgg taatgaaaaa aattctacaa aagaagggct atcttgtaga tatagcacta
    10561 agtggtgaag aagctataaa tataattaaa aaagataaaa attatgattt ggttttatct
    10621 gatgttatga tgaaaaatat ggatggagta cagctattag atagaattaa atctattaat
    10681 agagatatag aggttatatt agttacagga tatggaagta ttgaaaatgc agttgatgct
    10741 atgaaaagag gagctttatc ttattttata aaaagtaatc ccattgaaaa tttattagaa
    10801 gaagttgaaa aggtaaaggc aagtaaaata tctgtttctg tacaaaaaaa taattttgaa
    10861 tttactttgg aatctaaaaa tagagatttt aataatatca taaaaatagc aaaaaaagct
    10921 gcttgtaaag atgttaatat attaatcttg ggggaatctg gtgtaggaaa agatatatta
    10981 gctagatata tacatagcat aagtccaaga aagaatgaga tatttgtacc tgtaaattgt
    11041 tgttcttttt cagaaaatct attggagtct gagctgtttg gtcatgaaaa aggttctttt
    11101 acaggagcag tagatagtag aaaaggtaga tttgaacttt cgaataaagg aactctattt
    11161 ttggatgaaa taggagatat acctctaaat gttcaggtaa aacttttgag gacacttgag
    11221 gacaaatcta tagagaggat aggaagtaat aaatctatta aagttgactt taggttaatt
    11281 tgtgctatga ataaagaacc aaaagtggaa atatcaaatg gaaatataag agaagatttt
    11341 ttttatagaa taagtacaat aacaataact ataccaccac taagaaagag aagagaagac
    11401 ttaactactc ttatagaatt tttcttaaat aagtaccaaa ttgaacatga taaaaagata
    11461 cactcgattg ataaggaagt aaaggatttt ttattaaatt acaattatcc aggaaatata
    11521 agagaattaa aaaatataat aaatagactt gtagttttaa gtgaagaagg taatttatca
    11581 aaagacaatt taaatttaat atcaaataat gtatacatag atgataaaat aagtattaga
    11641 cctttaagag aaataagaaa agagtttgaa tgtgagtata ttgaaaaagt tttatctttg
    11701 tgtggaaata atatttcaaa tacagctaaa aaattggaga ttagtagaag acagttaacc
    11761 aataaaatat cagagtataa tattaagtga gaaaaaaact tctcattaag tgagaaaaaa
    11821 atttctcaaa ctgtattaaa agataaacag aaaaaatctg tttatctttt tttattataa
    11881 ttttaaaaat taatatttac aataattatt gctaaattca atattggtgt aaattaaaaa
    11941 tgaaaatttc tatgacatta atacatagaa tatatatttt aaataattgg catagaaaat
    12001 gctttatata ttaataaacg taataaatac ttttaattgc gattaaatat attaaggggg
    12061 attttcatat gaagctagag ctagggaata tatttataaa aaatgttgaa tttggagaaa
    12121 agacagaagt aaaagatgga gtactatata ttagtagcga agaaatagaa aagatagtat
    12181 tagaagatga aaggattgta agtgtaaatg ttgaacttgc aagacctggc gaatcaataa
    12241 gaatagctcc agttaaagat gtaatagagc ctagagttaa aattggagat gaaagcaaaa
    12301 tatttcctgg aattataaat aaagtgaaga ctgtaggaag tggaagaacc catgtacttt
    12361 taggagcttg tgttgtaact tgtggaaata tagttggatt tcaagaaggc gtaattgata
    12421 tgagtggtcc tactgctaaa tatacacctt tttcaaaaac aaataatata tgtattgtta
    12481 taaaagcaaa ggatggtata gatactcatg attatgaaga agcagctaga attgcaggat
    12541 taaaaatagg tgcatatgta ggtgaggcag gaagagaagt tgagccagat gaagtcattg
    12601 tatatgagac aaagccatta ttaaaacaag taaaagaata tccagacctg ccaacagtag
    12661 catatgttca catgttacaa tcacaaggac ttttacatga cacttattac tatggggtgg
    12721 atgctaaaca gatagtgcct acatttatgt atccaactga aataatggat ggagctataa
    12781 tatctggaaa ctgtgtagca ccatgtgata aggttacaac attccatcat ttaaataatc
    12841 cagttataca tgacttatat aaaagacatg gaaaagattt aaactttata ggagttattt
    12901 tgactaatga gaacgtattc ttagtcgata aagagagaag ctctgatatg gtagctaaat
    12961 taatagaatt tttaggagtt gatggagttc tagtgacaga agaaggttat gggaatccag
    13021 atactgacct aatgatgaat tgtagaaaat gtagtgaagt tggagcaaat gtagttttga
    13081 taacggatga atttcctgga aaagatggca agagtcaatc tatagcagac gctactaagg
    13141 aagcagatgc agttgtttct tgtggtcaag gaaatctagt ggttcatttc ccagcaatgg
    13201 aaaaaattat aggaacttta gattatgttg aaatgatgat aggtgggtat aaaggatgct
    13261 taaatgaaga cggaagcatg gatgcagagc tacaaattat aatagcatca actatagcaa
    13321 atggctataa tcatttgaca gcaagatatt attaaataag tatttgaata taaagttctg
    13381 ttgatgtaat cattggtcta actgatgtaa taactataaa gtgatttgga ggattaagag
    13441 atgagtaaaa tcagagtggt tcattatata aacaatttct ttgctggtat aggtggagag
    13501 gaaaaagcag atattccgcc agaaaaaagg gctggtgtag taggacctgg aatagcattt
    13561 cagagtcaat ttaatgatga tgcagagata atctcaactg taatttgcgg agatacgtat
    13621 tttggtgaaa atattgagag tgcaactcaa gaacttttaa aaatgataaa agaagaaagc
    13681 cctgatttat ttattgcagg cccagcattt aatgcaggta gatatggagt agcttgtggg
    13741 actatttgta aggcagttga agaagagtta aatattcctg taattacagg catgtataaa
    13801 gaaaatccag gtgtagatat gtttaaatta gatttgcata tagtgtctac aggaaattca
    13861 gcagcaagtc ttagaaaggt agttccaata atgacgaaac taggtcttaa attggttaga
    13921 ggtgaggaaa taggacctcc tgaagaggaa ggatatataa tgagaggaat aagaaaaaat
    13981 ttcttccatg aacttagagg gtctgaaaga gcaattgata tgttggttaa aaagatgaaa
    14041 ggggaaagct ttgaaactga gtatccaatg cctgaatttg atagagttac acctatgaaa
    14101 cctgttaaag atttatctaa gataaaactt gccctagtaa cttctggagg gatagttcca
    14161 attgataatc cagacaaaat tgaatcttca agtgctacta aatatggaat ttacgattta
    14221 acagatatgg attctatgtc aaataaagaa tttacaacta tacatggggg gtatgacaga
    14281 gcatatgtcc ttgaaaatcc aaatttagtt gtaccactag atgtagttag agagcttgaa
    14341 aaagaaggtg taattggaga attagtagat tattttataa ctactacagg aacaggaacg
    14401 agtgttggca attctaagag atttggagaa gagttttcta agaaattgtt agaagatgat
    14461 gtagatgctg taattttaac ttctacatga ggtacttgta ctcgttgtgg agcaacgatg
    14521 gtaaaagaga ttgagagagc tggtatagca gttgttcata tatgtacagt agtaccaata
    14581 tcacttacaa taggagctaa tagaattgtt ccagcagtag ggataccata tccacttgga
    14641 aatcctatgt taggagaaga ggaaagtaaa aaaattagaa agaatatagt tttaaaagct
    14701 ttaaatgcac taacagaaga tatagaagaa caaacagtat ttgaataata aaaatacaac
    14761 acaacactga aataaaaaaa gatatcaaaa aataattttt taaaattatt ttacgatatc
    14821 tttttttatt aggtaaattc gaaatttgca tttttttaaa ttaaatttat aaaagtgata
    14881 aattagttta ttataatatt gatacacaaa ttcaaattag atatactatg aaaagcgaga
    14941 ttattacatt ttggaacaaa tattcaacat attagatcat attaattgaa cagaaaaaat
    15001 taactttata taataattag aataatgata agaaagaagg tgtatatatt gatttcaatt
    15061 gccatttgtg atgatgaatc ctatatgcta aatcatttaa aggaaaatat agaattatac
    15121 atgaagcaga agaatttatt atataatata gagcttttta ataaagtaga agatttacta
    15181 tgcaatcatg aaaagtttaa tattgtattt ttagatatac agatggaaga gattaacgga
    15241 atgcaggcag ctagaaaatt aaggtcatat ggtaatgagt gctttataat tttcgttaca
    15301 gttttaaatg aatttgtatt tgatgctttt gaagtagatg ctataaatta tctgataaaa
    15361 cctctatcta atgagaaact atataaaact ttggataaaa tagttacaaa acttgatgat
    15421 aatgaaagta attatatcac aatacaaaaa ggttattcat attggaaatt aaaacttgct
    15481 gatattttat attgtgaagt tataaaaaga aagatttatg ttcatttaaa gaaagagact
    15541 gtagattatt atgagactat tgaaaattta gagagaagtt taccaacaaa tttttttagg
    15601 tgtcatcgta gttatataat caatttacaa tatgtatatg gatatgaaaa tggtaatgca
    15661 gttatggaaa gtggagatag aatacctgtt tctagactac gtcaacaaat attttcaaaa
    15721 gttatgcttg agttcatgaa aaataggagg atataagatg attaatttat tttcttccga
    15781 tttattttta aagtacagtt ttttcttctc ttttattgta tatagaattt taatggtaat
    15841 agtgcaatac tattttctaa tcaattttac aaattttaat tcaaaatttt ggtgttttat
    15901 tttatattcg ataatttcaa tttttttaat cattataaat acatatttta atttatataa
    15961 tttattttct tcacagattc tattttttct tatgactttt ttatttgtaa agtacataat
    16021 aaaacaatct actgttttat ctatagtatc aactttgtta gtatatttaa ttgaacaatt
    16081 agtatatgga tttacagctc cattaaatta cttgatattt actagtgata taaatacaga
    16141 tatttataaa tttgatataa atatgggact atcttcttta attactatta taatagctgg
    16201 atttatatat tggtatagtt ctaaaaagtt taatattaag gtcatgaact ttgataaata
    16261 tatagcaatt ttgatgattc cattgttgct tataatatta tttatgcaat catttgaata
    16321 tagttcaaat ataaatatag atacaagtct tgggattgta aagctgctat taaatacttc
    16381 tataactgaa gaaattcaag cttttctttt ttctataatt ggaactatat gtgtattttt
    16441 ttctctattt acctttaaga aactaattca agctctcgaa gatgacaagg agagggcaat
    16501 tatgaatcaa cagattcatg ctcaaaaaaa ctatattgaa gaagcgaaat cacgattatc
    16561 acaaactata tcctttagac atgattttaa taatcattta gctattgtca atggattgtt
    16621 gaaaaaagac caaattttaa aagcacaaga ttatttaaat aagcttgaaa aagtaacaag
    16681 tgacctatca ttttcttgta atacacagaa tattgttatt gatgctcttt tcaacaataa
    16741 attaagtata gcaaaacaat taggcataga ggtagattgt gaagtaatta taccccaaag
    16801 cactaacatg aacgattttg acctatgtat agtgtttgct aatgctattg acaatgcaat
    16861 taaagcttgt agagttgtag ataaacaaaa taggtattta aagctttcca ctaagttaga
    16921 gggtggattt tttatgatag aaataaaaaa tagctataat ccaataaata attatacaag
    16981 tggctcaggt ataggtcttt taaatataaa agaaattgct aaaaaatatc aaggggctat
    17041 aagtatagat aagacatcag actattttca aataaatgta ttgctagtta tttcattaca
    17101 ttgcgctagt atttgagaac aatttcattg aaaatagtat ttgtaagcta tattatgtat
    17161 ttgaaaagag aaagtttgat atatagaaat gaggaggtta ctaaaatgaa agttggaaat
    17221 ataaatggtc aagcaccaat tacaaatggt ttagatagtt gtcaaagtga ggtacaaggc
    17281 ttagaacaaa agaaaaaagc attacaggat gaaatagaga aagtaagaag tgataaaagt
    17341 attgatggtg aaacggccaa attaaaaata gaagctttaa aaaaagaaat ggaagagatt
    17401 gaaaataaaa ttcaagagtt aaaaggaaat aaaggaaaaa aaacaaataa agaagaaaat
    17461 aacgtttcag aagtaaataa taatctatta gagagaaaaa aagaaccttc taataatgaa
    17521 aatgtaaaac aattatatga tgtttttgaa agaagcaatg tagacgaaca atgggataat
    17581 acttatcgtg ttctccaaga tgataaaaac ttaaaagtaa aatttaatag acctatatag
    17641 tttatttata aaaatagtta atattttaat tatcaccact ttttagaaga atacacactt
    17701 tattttaaag acccacatat ttatttacag ttagcacatt tatatgtggt tttataacta
    17761 ttatttacaa gtctatattg ataactttta catagtatat gatgtttaaa tacttattca
    17821 aatttatcta tacataaaca aaaaaagaga ttttaaaatc tctttttaga ttgttgactt
    17881 atggcttttt gatttaataa aatcaagaag ccgtttgaat tttatatgtt ggctgatacc
    17941 cttctgatat tgaaacacca tttttgtttc caaaatcgtt taaaattaag aacttattat
    18001 gaatgactat ttcattatga acaataagca aataacatga atcttcaatc aatgttttaa
    18061 cagtagcatt aaatgcttgc ttatatagtt ctatcgtttg tttgaactgc ccattaaagt
    18121 aaatatgagt caataacata actatatcta cacaaattaa tataaatttt ttatactgta
    18181 cattatctaa ctgttgatta tctgtattac aacatgattg aatttaaaaa gccatcaaca
    18241 catagaatgt tgatggcctg aaaatagatt ttaaaatctc ttttttatta tatattaatt
    18301 attttttaaa tttatatttt ttgcatcaga ttttctaata gctaagtcaa accctctaaa
    18361 tctaatcact atagggtcat taagaggagc tatctttttc acttcaactt cagtgccatc
    18421 tattagtcct aaggctagaa gtctcttcat aagtttttca tttccagcta tattgtctat
    18481 aattcccttt tgtccaagtt ttaagttgta aacagtcatt attaacacct cctaatgaaa
    18541 atcattatca aactttatat ttataatata taacaaaaag agcaaattgt caatatataa
    18601 caaaaaataa acatactaag ttagtatgtt tataaaaaat agtatacatg ggatactaat
    18661 agcatctagc aaaaaaccac ttactaatgg tacaactaaa aaggcttttg gagaatcacc
    18721 atatttttgt gtcaaagaac tcatatttgc cagagcgttc ggagtagctc ctattccatg
    18781 tccaatcaaa ccacttatta tgatggcaga atcaaaatct tttccaagta ctctaaagca
    18841 aataaatatt gaaaatagga ttataaagat tacttgaaaa gttactatta agagaatagg
    18901 aggtaataat gtagataatt caaataaatc tatattcata agtgataaag ttaaaaaaat
    18961 tcccaatgaa agttctttta aaaaatctat aagtttaaaa tttaattcta gtatatttat
    19021 cttatcattt aaatttctaa aaataacagc cgaaaacata caagttacaa cagagggtaa
    19081 tagtatatta aacgttatat agaagcatct acttataatt tctcctgtat ttatacaaat
    19141 aaatatgaga agaacctgtt ccaaaaatac agatggtgtt attgtttcgg agaagttatt
    19201 attttttatc ctattcttat ttctaaaaaa tttacttcca aatctcttta gatttctatt
    19261 atatctagga atcgacaagt ctatatttga tgatggtttt aatttatatt tatttattag
    19321 aaatttagct acaggacatc ccaatatacc acccataata agtcctattg ttgcagcaga
    19381 taatccaacc ccaactgctc cttctatacc aagattttct attgtaagtc caaatgcagc
    19441 agaataacca tgaccacctt ccatagatac atttccacac ataagcccta aaagaggttc
    19501 aagttttata atctttgata ttgtaatagc taatatattt tgacaaaatg ccaatactcc
    19561 acacaaaatc caatatctaa ataatacact accacctttc tttataagat ttatgcttat
    19621 ttcaagtcct atagttgtaa aaaagaaggt tatgaaattt ggcattaaat ttccacttat
    19681 agatatatct gctatattaa aatatttaaa aaataaattt agaaaacaaa ataatagacc
    19741 tcctattact ggtgcaggta tacagaaatt atttaaaaag ttaactttat tcttcaataa
    19801 attaccaatt aaaaagaaga atatagatag tgtcaaggtt tgcactatat caaaacttaa
    19861 ggtaatcaaa ataagtcctc ctttgtaatt caaagtttta attatataac ttaaattctt
    19921 atgtattgaa attttattat caaatgtata ttaataaatg tatattaaaa agaatcagta
    19981 gatataatta gatagtcata aattaaatta aaatatttta atgagatatg acttttttag
    20041 aattaaaaac cgtagtatat tgatataata gaaataagac ttaaaaatct gttgatagta
    20101 ttatttataa gtacagtagg aggataaaat gtttgaaaat ttacctaaga tagatttaca
    20161 ttgccactta gatggaagtg ttagagtaga aaccatgctt gatatagcta ttaaagagaa
    20221 aatagattta ccttcaaata atatggatga aataaaaaaa ttagcaaagg tttcttttaa
    20281 ttgtacttca ctagatgaat atttagaaaa atttgattta cccttaaaag taatgcaatc
    20341 taaggaaaat ttaaaaagaa ttacttttga acttttggaa gatgcaagta gagaaaatgt
    20401 aaaatatatt gaaattagat ttgcaccatt acttcacacc caaaaaggta tgagtgttaa
    20461 aaatataatt gagggtataa ttgaaggaat tagagaagct gaaagtattt atgatataaa
    20521 aggcaattta atattaggtt gtatgagaac aatgacctca aaagaggcat tattagtaat
    20581 tgaagaaggg aaatcatttg taaataaagg tgttgtagca gtagacttgt gtggtccaga
    20641 gaaagaggga ttttgtaagg aatataaaga tgtttttaaa ttagcaagag aatatggata
    20701 taaagttaca atacatgcag gagaagctgc aagtggagaa aatgtattgg atgctataaa
    20761 tattttaaag gcggatagga ttggtcatgg ggtaaaaatt aaagaccata aaaaggcgta
    20821 taatttagtt aaagataaaa aaatattgct tgaattatgt ccaactagta atgtacaaac
    20881 taagacagta gattcttatg aagcacatcc attttatact ttttataaag ataatttaca
    20941 tgtaagtata aatactgata atagaactgt atcagatata aatttaagtt cagaactaaa
    21001 tgttatattt gatactttta aactaggatt agaagactat aaaataattt atagaaatgc
    21061 agtagaagct agttttgcag ataaagaaac taaagagtat ttgaatagtt taatttaata
    21121 gataaaaata tttaaacttt aaattaagct attaaattga taaaaataca ttgtattagg
    21181 agaaaaaatg tgaaagatta tgaagatgtt gtttatatta aactagtcaa aaaagaactt
    21241 gaagaatgga agaaaaatat attaaagaaa ccttctatat ttgacaaagc atcaaagggt
    21301 atacagaata aatttaatgg agtattgcca gataaatatc atgaaataat tacttcttct
    21361 ataaaagtaa tgacaaaaac cgtactgttt ggatataaat atgctacaaa gccatcactt
    21421 agaaatatgt cattagaaga aagagaaaaa ttagttttag aaaaagctaa aacttacaag
    21481 actacagcaa tgattgaagg ggcaggaaca ggggcaggag gaatcctctt aggtttatct
    21541 gattttcctt tgcttttagg tattaaagtg aaatttttat atgatgtagc ttcaatatat
    21601 ggatatgatg ttaaagatta tagagaaagg atttatatat taaatatatt acagttggct
    21661 ttttctagtc aacagcatat aaacaaaact tttaaattga tgaataactg ggatgaatat
    21721 gtaaatagtc taccagaaga catcaatgat tttgattgga gaacatttca acaagagtat
    21781 agggattatt tagatttagc taagttttta caactaatgc ctggaatagg agcatttgta
    21841 ggattttatg tgaatggaaa attaattgat aaattatgtg aaactgctgt gtctgcttat
    21901 agattgagga ttcgagagct taagttataa gagaaattat aacataaaaa attagttata
    21961 caatatatct atatgtatct aattttgcat tgataaaaac aattatggat aaaaggtaaa
    22021 gcatgataga atctaatgta gaggtttgta ttttaatgga aaaatttagt ttttattgct
    22081 taagatacaa attgaattac gaagagaagt aattgggagg aatattttca tgacaaattt
    22141 gccaaaacaa tttgatagct tcaatgaagc tagacaaaaa ggatttataa atgcaaagga
    22201 acttaaggaa agtgggaaaa agatggttgg agttttctgt acatttactc cagttgaaat
    22261 tccaatggca gctggagcaa ctgtagtagg tgtatgcggc gttagtgaag agccaatacc
    22321 tgatgcagaa agggtgcttc caagaaatct ttgtccttta attaaatcaa gctatggaca
    22381 tgcaataaca gatacctgtc cttatttcta tttttctgat ttgttgatag gagaaaccac
    22441 ttgtgatggt aagaaaaaaa tgtatgaaga acttgcaaaa gttaagccaa catatgtaat
    22501 gcatttgcca aatacttcaa aaggagaatt tgcctataaa ctttggaaag atgaaatgat
    22561 aagattaaaa gaagaggttg agaaatcttt aggtgtaact ataactgaag aagatataag
    22621 aactgctata aaagataaaa atgaagaaag agaactttta aaagagtttt atgcacttgg
    22681 taaattacaa ccatctgcac ttacaggcct tgagttacat aatgttttat atcaagcagg
    22741 ttttaaattt gaccgtgcag aacttaaaca ttctttaaga aaagttatag atgatatgaa
    22801 agaaagatat gaaaaaggtg aatgtcctgt tcaaaaagat aagccaagaa tattgataac
    22861 aggttctcct attggtggaa taagcgaaaa aatagttaaa actttagaag atgcaggggc
    22921 atcagtcgtt gcatatgaac tttgtggagc tattagatca aacgatttat tggttgatga
    22981 agaaatagaa gatgtatatg atgctttaac acaaaaatat ataaatatag gttgttcttg
    23041 tatgatgaat aatgacaatc gtattgaatt attagataga ataatagatg aatataatgt
    23101 agatgctgta atagatgtag ttttacaagc atgtcataca tttaatatag aaagttatag
    23161 aataagagaa tttgttacaa aagaaaaaaa taagccattt atgtctcttg aaactgatta
    23221 ttcaaaatca gatactgaac aattaagaac tagatttgaa gcgtttgtag agatgttgta
    23281 ggaataaata aaagtaggag gaactatgtt tagtatagga gttgactcag ggtcagtggc
    23341 aacaaagggt gtgctatttg atggtgaaaa aattattaag aaaataatta taccaactgg
    23401 atggagccct aaaagtacat ctaaacaggt ctatgagttg ctaagtagtg aaattgacaa
    23461 aaaagatata aaaaaggtgg taggtacagg ttatggaagg ggagtaatgg attttgctga
    23521 taagaaagta acagaaataa cttgtcatac tagaggtatt tactttttaa acaagaacat
    23581 aaggactatt ttagatgtag gtggtcaaga tagtaaagtt ataaatttag atagagatgg
    23641 aaatgtattt aactttataa tgaatgataa gtgtgctgca ggaactggtc gatttttaga
    23701 gattacttct aaccttttag gaagcgatat tgaaagtata gatacattag ctaaaggata
    23761 tgaaccagtt aatatatcta gtatgtgtac agtttttgct gagtctgaaa ttgtaagtct
    23821 tctagctcaa aacatttcta ctggagaggt agcagcaggg atacttaaat ctattgcaaa
    23881 taaatccacc tcaatgttag caagaggtga ggtaatagat gaagttgcat ttactggagg
    23941 gcttgcaaaa agtaaagaac tagtaaaaat gatagaagaa atactgggta aaaaaatttt
    24001 tattgcagaa gatactcaaa taataggagc tttaggagct gctgtaatag gatttagata
    24061 aaaacatata aaaggaaaat gagaagctga atttattata aataaattca gttttttatt
    24121 ttattttatt tatttataaa ggaaaacttt ggtataattg atttaaatga ttgtatattt
    24181 gtaaatactt gatatttagt catatataac attataattt taaaaattag ctcaaaataa
    24241 gggggagaaa gcgtgaaaaa atttacttca aaaaaagtaa caaggtttgt tgcgctgttt
    24301 ttaatatcta ttttagtaat gtcaacaatt cctgtatcag ctgacaatag caatacattg
    24361 aatcagataa aaaaagcaga atacagtgag acgtataaac aatatctaaa tgatgctaaa
    24421 aatggacgta cagaaaaata taatgggatt ataccaaatc catatcagtt ggaaggtact
    24481 caaatccaaa gtaaaggaag aacagctcca acatcttatg accctagaaa attaggtctt
    24541 atgacatcaa taaaaaatca agaggattta ggaatctgtt gggattttgc tgcaatggca
    24601 accttagaaa gtttcttaaa gttaaataat tatggagact atgatttatc agaagaacac
    24661 ttaagatggt gggcttcaga tggtgaatat ggatggtctg taaatgatat gaatggtgct
    24721 ttaaattatg aagctatggg atatttaaca tcttggtcag gtcctaaact agaaaaagat
    24781 attccataca atggtagagt atctaaagca caaggagcaa aaaaaccaac taatatgaat
    24841 acagcaccta ctgtttttaa tgtgacagat gctgtgtgtg taagtaatga cataaattct
    24901 acaaaaaatg ctatattaca gtatggagca gtaacatctg gttattatga agatattaaa
    24961 tatcaaagtg atgaccaaaa ttcatattat tgtccaacaa aaagttttaa tacaaatcat
    25021 gctatttcaa ttgtaggttg ggatgataac tattctaaag ataattttaa tgcaaatatt
    25081 agaccatcaa aaaatggtgc ttggttaata aaaaatagct ggggagatta taattctgag
    25141 ggtggatatt tctggatatc ttatgaagac aagacactta tgtctgatat agataatttt
    25201 tcaatcaaag gtggtaaaaa accaaatgat gatgagaaga tgtatcaaca tgactatgca
    25261 agtattgtac ctttaatttc aaaaaagata acagctgcaa atgtatttga tttcaataga
    25321 ggcgatgaaa ctctaaaatc tgtaatgttc ttaactgaaa gtataggagc taagtatgaa
    25381 gtatattatg ctccagtagt aaatggtata cctcaagaaa acaatatgaa aaaattaaaa
    25441 gaaggtactg cccaatattc aggatacata acagttccaa ttgattcttt tgatatacca
    25501 gaaggaaagg gtgcaattgt agtcagtata gaggggaaaa atggagagtc aactataggt
    25561 tctgagtcaa atgtaccagg atatgataca tttaaagcaa aagctaattt aggtgaaagt
    25621 tatatcatag ataatactgg aaaattcttt gatataaata gagatagtaa cttctatccg
    25681 tgtaatttta ctataaaagc tgttacagaa aagtcttctg gtgagagtat cccaaatgag
    25741 tctttaattg gtagtgatag atatgaaact gctatcaaag ttagtcaaaa tggtttcaat
    25801 tcttcagaaa atgtagtttt agtaaatggc agttcaatag tagatgcatt ggcagcaact
    25861 ccttttacat ctgctataaa ttcaccaata ttattgacac aaaaagaagc tttaaattca
    25921 aaaactaaag ctgagataca gagattaggt gctaagaaag tatacctaat aggtggagaa
    25981 aattctataa gtaaagaaat tgaacaacaa ttaaaaagct taaatatatc gatagagaga
    26041 atatcaggaa gtgatagata caagacaagt ttattattag ctcaaaagtt aaatggtata
    26101 aaaaatgtat ctcaaatagc agttgtaaat ggagtgaaag gattagctga tgcaattagt
    26161 gtaggcgctg cagcagcaga aaataacata ccaatcatac ttgcaaatga aaagagcgaa
    26221 ttgcaaggag ctgatgaatt tctaaattca ttaaatatag agaaatctta tattattgga
    26281 ggaacagcat ccctatcaaa caatctagaa agtaagttaa aaaatccaac tagattatct
    26341 ggtagtagta gagacgaaac taattcaaag ataatagata atttttataa aaaagatact
    26401 ttaaaaaatg catttgtagt taaaaatgga atcaagaatc aaaatgattt aatagatgga
    26461 ttggcagttg gtcctttagg agcaaaaact gggtcaccag taattttagt tggtgataaa
    26521 ttagctgata gccaaaaaga agttcttaaa aataagactt tagaaaaagt aactcaagtt
    26581 ggtggaggag caaataaaaa tgcatttaaa gagttagtaa aattaaaaag tgctaaatag
    26641 agtacttaag tattaacata tattagtgtg tattagtaac ttatcttaat aaaagctgaa
    26701 aataattact tcaaattatt gataaataag ataatcaatg attgtaaagt tttgttttca
    26761 gctttaaatt tatgtagtat aagtttaaaa acataaaaaa gggttacttt atatagaaat
    26821 atagaaaatc ttacatttta tatataaata acccatattt aattaacttt ttatagtgtt
    26881 ctaatagata ttattgaact taatggtaaa tataatgtgt aagtttcatt taaagttgga
    26941 ttagattcat ctatatatct tgagcaaagt gtaattgata agctatctgc ttctataatt
    27001 tcaccatata gaggacaact gctaaagtaa gaatgtactt caacatattt atttaagttt
    27061 tcttgaacat aatcgtaaaa acggtttttt gtagtagtag ccataaaatc aactccttta
    27121 ttttttatta aagttgaaac ttttaaaaag ataaatatga ttacttctat tagaaactaa
    27181 gttaaaaaat aagcaaatag atatgaaaat tagaataata tattatttat atcttaatta
    27241 taacactaga taataaaaaa tgctatataa aattcagaat tttcgaaagt ttttaagctt
    27301 atttttaaat atactaataa tactattgac attagataga aaaagtatta tattgactat
    27361 ataaattatt ttagtcaaac tggagggaaa agatgcctaa atcgtattct gataaagaaa
    27421 gagagtatat aataaaaaga cttaaagaag aagcaagatt gtgtatggag caatatggta
    27481 ttagaaaaac tactgttgat gagcttgtaa aacgggtaaa aataccaaaa ggaacttttt
    27541 atctattttt tcaatcaaaa gaattgctct tttttgaggt attaagagat atacatgact
    27601 ctatacaaaa agaaatctta tatgagataa atagagtaga tgaaagtatt acatgtgaac
    27661 aattgacaga tatatttatg aaattctata ggatggttga tagtacttca attttaaatc
    27721 ttatgataaa tggagaattt gagatattgg tgagaaagtt accagattct ataattgaag
    27781 aacactttag acatgatgac tttgaaattg gagagattat atcttgcata ccaaatgcaa
    27841 aaaataaaga catagaaagc tttagtggag catttagagc agtttttctt accatgctat
    27901 ataagcgcga ggttggaagt aattgttttg aagatgcttt aagattaatg ataaacggat
    27961 tagttataca acttatggaa tagaatttaa attttgtttg ctaataactt ttattaaaaa
    28021 ttattaacaa acaaaaaaat tatattttat tgaccatata gtcaaaatag tcaaaaattt
    28081 gaaagggtga tattgaatga ttaaagttga tgatttatca tttagttata cagagagaga
    28141 ttttttacaa aatattaact ttggagtagg aaaaggggaa atactaggat ttttaggacc
    28201 atcaggtgca ggaaaatcta cattacaaaa gattctaatt ggaatgataa ctaattatgg
    28261 aggaagtgtc attgtaaatg gagtagagag taaaagacac tcaaataaat tttatgaaaa
    28321 tataggagtt gattttgaat ttcctagttt atatgaaaag ttgactgcaa tagaaaattt
    28381 aaaatatttt gggtctctat attctaaaaa actactatct attgatgagt tattaaaatc
    28441 agtaggacta gaaaatgaag caaataaaag ggtatctgag tattcaaaag gtatgaaatc
    28501 tcgattaaat tttataaaag ctttattaca taatccagat attttatttt tagatgaacc
    28561 aacaagtggt cttgacccat caaatagcaa ggttatgaaa gatataattt tatcagaaaa
    28621 atctaaaggt aaaactatta ttttaacaac tcataacatg ttagatgcaa cagagctttg
    28681 tgacagagta gcgttcattg taaatggtaa aatatctgct ttagatacac cacataatct
    28741 tattatgtca aaaggagcta ttaaagttag atatacttac tttgataatg gagaaaaaac
    28801 ttctgaatgt tttctgaaca atactgctaa tgataaaaat ttgaatatgc ttattgagaa
    28861 aaataaactt ttatcaatac atagtagtga accaacatta aatgatattt ttattgagat
    28921 aacagggagg aatttacaat gaggctaaaa aatcttattt taggagatat aaagtttcaa
    28981 tttaagtatg gtttttattt tttatatctt tttttaagta ttatatatat ttgtattatc
    29041 aatgtatttc caacttttat gagagaaaaa atagctataa ttatgattta ttctgaccca
    29101 gcagcaatgg gattgttttt tatgggagct attgtacttc ttgagaaaag tcaaagggtt
    29161 ttaaattcct tagctgtatc tccagtaaaa gtatctgagt atattttatc aaaggtaatt
    29221 tcattaggag taatatctag tattgtagct atgtttattg ctattacatt aaatttagat
    29281 aatattataa tatcaactat aggtaccttt ttttcttcta ttatattttc tttgcttgga
    29341 ttgatacttg caagtaaagc atctagtttg aatcagttta ttgttttaag tattcctatt
    29401 gagattatat gctttattcc accaatactc aatgtacttc ttgacacaaa atcatatgca
    29461 aatttgtacc cttttaatat atgtatttct cttattagtg gagataaaaa ttttataatg
    29521 attaatattt taattttaat atcaattata ataataattt attttataac ttattatttt
    29581 atttgtagca gttggaaaaa ggtaggtgga gtaaaactat gataaagatt ataaatgcgt
    29641 ttaaacaaga gtttgaacaa attaagagag atgctatgct ttttatagta tgtgtttctc
    29701 caatattatg tggagtattt ataaaatttg gaataccatt aatacagaat atatcactta
    29761 acaagtttta ttatcaatta aatttagagc cgtatttctt gatgtttgat ttacttttag
    29821 cttttattac accttttatg ttcttttttg cttctacaat ggtcatattg ggagaaattg
    29881 atgacagcat ttcaagatat ttaatagtaa ctccgcttgg taaaactggt tatcttattt
    29941 cacgatttgg aataccaggt atcttagcat ttattattac tatgattcta cttatctttt
    30001 tttctctaac taaaatttct ttcttgttaa acttatcaat ttctttatta gttttattac
    30061 aaggaattat tatatcaata ttagtgattt ctttatcatc aaataaacta gaaggaatgg
    30121 taattacgaa attctcaggt gtttttatga tgggtatttt agcaccattt tttattttaa
    30181 ataaagcaca atatattctg ttcttcttac caactttttg gatatcgaag gcatttaagg
    30241 aagataatta tgtctatatg tttatttcaa ttgttatatc attaatatgg attttattat
    30301 tatttaaaaa gtttagtaaa aaaatagtta aataagaaaa tttaatatat aaatgtaagg
    30361 ttgacttgac agtaatgttg aaaaatgtta catttaagat gtaaagttaa ccttacatga
    30421 atggagcaaa tatgaaaaat aaaataaaga tattaagaga aaaattagga ttgacacaag
    30481 aacaactagg gagattagtt ggaacatcta gacaggctat aaatgctata gaaactggta
    30541 aaaatgaacc ttcaatatgg ttggcatatg atatttcaag aatttttaat gaaccaattg
    30601 aaagtgtatt tttatttgaa gaaagtgaaa gaaaatcaag agcacagata agtaggggag
    30661 aatattatgg ctataagaaa gataagaaca tttgatgatg aaattttaag aaaaaagagt
    30721 aagtatgtag aaaacgtaga taataagata agagaaatat taaatgacat ggcagagacc
    30781 atgtacaata ctccaaatgg aggaggatta gctgcatgcc aagtaggagt attaaagcga
    30841 ttagttgtta tagatttagg agaaggactt attaagcttg ttaatcctga aattattaaa
    30901 caagaagggg aacaaattgt tgttgaagga tgtttaagtt ttcctgaagt atggggtaaa
    30961 ttaaaaagac caaaaaaagt tacagtgcaa gctctaaacg aatacggtga gaaaatagaa
    31021 attaaaggtt caggttttat ggcaaaatgt ctttgtcatg agatagacca tttaaatggt
    31081 atagttttta cagataaaat tattgaacat gtaaaattgt aagatagatt ggttattgaa
    31141 tttataaaat attttatagt aaggagttaa attatgagat tatggcataa ggatttaatt
    31201 gatgtattac ctaaaaatca attagtaagt caatggagag agctacttgc tataaaaggt
    31261 tctatagata aaaaaggtac tccaaaccat ctattagtga ataaagtatt gaattatagt
    31321 atagatgaat ttaaatttta tacaaaaatt gtacatgatg aaatgttaaa aagaaattat
    31381 aaacctaatg aacttaaata tacaagtata ttaaaatgga aaaatagaaa ttttgcaaat
    31441 gatatatcta atgaacatag tttaaattta gaaaatttat atgatgattg gcataataaa
    31501 atgtatttaa agcaatgctt atataattta gaagaaaaag caacatgtgg aggaatacca
    31561 ataaatgaat ggaatatatt actttgtaaa tatagtaaag attatgaatt gtggtctgga
    31621 aatatcatgt tttaattact atagattaac attatagtat tattgtatat aaagaggtga
    31681 ttatttgtat aataaaataa aatatattcc aataaattgt gaaatagctt gtaataaatt
    31741 aaaaaggagt atgccatata aatgggattt aaatatttat cgtggatgtg agcatggatg
    31801 taaatattgt tatgctattt actctcataa gtacatcaac tccaataatt attttgaaga
    31861 gatttatgta aaaacaaata tagtagaaaa acttgagaga caacttaaaa gcagtaaatg
    31921 gaagaaagaa gtaatcaata taggaggagt tacagatagt tatcaaccaa tagaagctga
    31981 ctataaaatt atgccagaaa tattaaacct gctaataaaa tacaagacac cagctattat
    32041 ttctacaaag tcagatttaa ttttaagaga ttacgattta attgataagc tatctaggat
    32101 tacatatatc aatgtagcat ctacaattac cacagtaaat gaagatacac aaaggcttat
    32161 tgagccaaat ggtgtggatt caatgagacg atttaaaatg ttaaaagaat ttagaaaaac
    32221 taacgcatca gttggtctac atattatgcc aattatacca tatattacag atgattttga
    32281 taatataaat tcgctattta gacatgcaaa agaatgtaat gtacattatg ttttacctgg
    32341 gactttatac ttaaggggta taactagagg tgtttttttt gactttgtta aaaaagagtt
    32401 tcctgaatta tttgataaat tatcaatact atatagtgaa ggttcactta atagggagta
    32461 taaaaatcaa ttgtataaaa tggttaatga acttagatat aaatattctc tatcaagcag
    32521 ttactctaaa ataatgaagg aaaagttaaa aaactcagga gatgtacaga tatctttttt
    32581 tgattagttt tatataaaaa aatttttttt actatgatga ttaaaattta ttaaaattaa
    32641 aatttattga caaatataaa atttaaatat ataattaatt cataaaataa aaatatgaaa
    32701 ggatgatgtt gttcggtgat atttgatatc ataaaatcgt tgatataagt attgctggaa
    32761 aagagtgaat aaaatcaaat ttaataagca aacaaagtaa agctatagtt ttattgttgt
    32821 gcttaaaaat atttggttct attttactct tatttaaact catctttttg aagttaaacc
    32881 acagagtaaa ctctgtggtt tttttatttt aaaaataaat tttaaggagt ggtatgtttt
    32941 gttaaacaaa ttatgtatgt atttagaaag accagagctt tataaacaaa gtgaaattaa
    33001 tttttgggat gatgagtata tttcagagca attattaaaa gcacacttag acactaattt
    33061 tgaaggagca agtagaaatt ttaactttat cgaggattct gtaaattgga tagttacagt
    33121 tgcaaatcca gttaattatc ctaaattact tgatttaggt tgtggtccag gtttatatgc
    33181 agagaaattt gcacaaaaag gttataaggt aactggaatt gatttctcaa aacgttctat
    33241 taactatgca caaaatagaa ataaggagac taatttaaat ataaattact tgtttcaaag
    33301 ttatttaaat atgaactata atgaggaatt tgatttggct accttaattt attgtgatta
    33361 tggagctttg tcaactgaaa atagaaggtt attaatggaa aaaatttatg atagtttaaa
    33421 acctggagga aaattaatat tagatgtatt tacaataaat aaatacaata attttgagga
    33481 aattaaatat tgggaaataa atgaagatgg aggattttgg agtaatgaaa aatatatgtg
    33541 tctacaagat aattgtaaat acaatgatta taatacatta gaacaaactc ttgtaataac
    33601 cgaaaaagat gaaaatgtat tttatgtttg gaatcactat ttttcaaaag aaagtttctt
    33661 attagaagtt gaaaatattg gatttaagtc tgttgagttt tttagtaatg ttaagggtga
    33721 agcatattct gacgatagta tgactatggg attagtttta caaaaataat aattttttta
    33781 aaatgaataa ataaaaactt gaaaccttta acaataaaat aacataagaa aagcttacat
    33841 attgaaaaat ggaaactttt atgttatttt tagtacatta caaatttgtt tatataaaaa
    33901 tcaatacttg aattattatt tttatgtgaa atttatctat agtatatttt tataaacaag
    33961 taatgttatt aaaattaagt atatagttaa aagtgtatag caaaaaggct gttatattaa
    34021 tgttagaggt tcagggaaaa tatataaagc aaagatattt acagataatg tagattgcac
    34081 agctataagt tagataatag aattatgtaa tcaagaattt acaacaaagt ataagataag
    34141 gataatgcta aattgccata caggtgctag atgtgtaaat ggatttaatt aatactattg
    34201 ataaagtgca acaagcacat aaaccaattg atgagattat tgaaactata agagatatag
    34261 ttgacataat taaaatattg gaacctgttt ataattttaa atcaaatcaa taatgattaa
    34321 gattaaaata atattaaggc atcaatgtta taagagtaca atataaggag tactatatag
    34381 tactccttac ttatacatat taggcaatag ggaatttttt tatagttaaa ttttcaaata
    34441 ttttttaggg aactttataa ttgagaatta agggtatagt atgtgatgaa cttactaaat
    34501 ttataattag gttatataat ggaataatca tcaatagttt tactttaggg aaaatatatg
    34561 cttaaggaag tatagcttac taatattatt aaaatgtata tttaaaatga taaaaaaaga
    34621 attagacaag tatttagtaa attgactatg caaaattcta tcaagcagga acactatgac
    34681 tttagtcatg ggaggttcag taggtaactt gttgaattaa gtttatatta tttaaataaa
    34741 ctacttaatt tagataatat aaaaagtcag aattttaaga atagagctat ataatcttag
    34801 ctattaggag aagtactatg ataggaatat attttagtgg aacaggaaat tcaagatact
    34861 gtgtagaaaa atttttacaa gaatatgata taacagcaaa ttcttattct attgaagata
    34921 atgaactttt acagcacatc aataatcatg agaatattat ttttagttat cctgtgcaat
    34981 atagtaatgt gccaaaaata ttgaaagatt ttataataaa tcattcaact ttgtggaatg
    35041 gtaaacgtgt ttttattatt gcaactatgg ctctatttag tggagatggc tctggtgtgt
    35101 tagctagaat attaaaaaaa tacggtgcta taactgttgg tggattacat gtgaagatgc
    35161 cagatagtat aggagatgaa aaggtattaa aacattcttt agagtataat agaaagcttg
    35221 taataaaagc agaaaagaaa gtaactaaag ctgctaaaaa actgaaacat gggtcaccac
    35281 caaaagaagg gttgggtttt ttgagtcata ttgtagggtt atttggacaa cgattgtatt
    35341 ttatcaataa aacaaatatg tatacagata aactaaaaat taatactgag gaatgtattg
    35401 tatgtggtaa atgcgttaat ttatgtccaa tgaagaatct agtaattaaa aattgtatga
    35461 ttgttgcaaa tgggcaatgt acaatgtgtt atcgttgtgt aaataattgt gccaaaaaag
    35521 caattacatt gttaggtaaa aaagttgttg aacagagtaa tattaaaaaa tatatgtaag
    35581 aaatttaaag ttttattgaa tgtaaattga tgtatatttt atgttagaaa gagaggttaa
    35641 ataatggaat actacatagt tgattcattt gcaactaaac tatttaaagg aaatcctgct
    35701 ggagtttgtg ttcttgacag aagaatacct ttagagttaa tgcagaaaat agcagaagaa
    35761 aacaatttac cagaaacagc atttgtagtt aaatgtaaag gaaattatga attacgatgg
    35821 tttactccta aagcagaaat tgatttatgt ggtcatgcaa ctttagcagc agcttatgta
    35881 atatcaaatt ttattgatgt taatgtaaaa aggatagatt tctttactca aagtggaaag
    35941 cttgaagtta cacgaaatgg aaatctatat gaaatgatat ttccagaaat aatgcctatt
    36001 gaaatagagt tatcaccaca acaagctaat ttgataggct gtgtaccaag tgctgtttat
    36061 tcttcaagag atttaatctt attgctaaac agtgaacaag aagttataaa ttataaacct
    36121 aattacgcac aattgcgtaa attgacagac tggttaggta taataatcac agcacaagga
    36181 agtaatacag attttgtatc aagatatttt tgtccagaat tagattcaga agaccctgtt
    36241 actggttcat cacattgtaa tcttattcca tactggtctg aaaagttggg aaaacacaaa
    36301 atggtagctg ctcaactttc taatcgtggt ggtataattc agtgtgaagt gttgaaggat
    36361 aatactgtaa aaatttctgg tgaagcagtc ttgtttatgc agggaacaat aaagattgat
    36421 atttaaataa gtataataac taatttatta tgaaaaataa ttaattttct tagtgttaac
    36481 aataataaag tagagttaaa aagcttgatt tcacttaaat caatatgata gatgttgata
    36541 ctaagattga caagcatgat taaaaaagat aatatttaat ctataaagat aaaaacacag
    36601 tctggttggt agtccagacg cagcaatagc tgtcagtaac ctgcctcctt ggttgtccgt
    36661 tctttagaaa gtaatttaag gaggaactag caatggacaa aattagtgga aaattaacag
    36721 ttttatttga agaaccattt tgggtaggta tatttgaaag acaagatggt aaaaaatatg
    36781 aagcatgtag ggtagttttt ggagcagaac ctaaagaagt agaagtgtat gaatttatac
    36841 ttgaaagatt tttctcatta gattttggta gcattaaatt agaaaaaaat gtgaccaaag
    36901 acaacattgg atacaaaaga atgcagagaa aagtaaaaaa ggaacaagaa aaagaaacta
    36961 tagggactaa ggctcaaaat gctcttaagc ttcaatatga agaaagaaaa caggatagaa
    37021 aaaacctagc taaaaataga aaagaagaag aaaaagaaag actatttaat ttgaaacaag
    37081 aaaagagaaa agctaaacat aagggtcatt aattttaatt aaatatcttt ttaataattg
    37141 ctagaaaaag gtgtataaaa tttttaattt tatacacctt aatttattga aaagaataag
    37201 gttttatatt tcaattactt taaaatataa aaatatacta ataaaaattg taaaaatagt
    37261 ataaatggta taccaaatgt aaatttaatg tgtttagttt tatgtctaaa agaatacatt
    37321 ccaattatag aacctatact acctccaatt actgctatag acataagagt agcttctttt
    37381 attctccatt cgtttctaat tgctcttttc ttatctatgt acattgaaaa gaaagcaata
    37441 gaattaatca ctataaaata tattagaata aaatttttca cagtcttgcc tccataaaaa
    37501 tatattatac attataaaac aagatatttg ttttggaaag ttaaatttgt aattagtaca
    37561 tataaaatat ttgataagaa caaatataat attaattgga aaatttaaaa aaattaaaca
    37621 attagcaaat agggggtata tttataagac acaaagtgat aaaatctatt tagaaaataa
    37681 tgtaaaataa caggaggata aagcaaaatg aaatttatag tagaaaaaga agtttttgat
    37741 aaattagaaa atgtatgctt tggtgtagta gttgcaaaag gaatagataa tactaaagaa
    37801 atagaaagaa taagcaacct tttagatata agtatagata gagtagaaga ttacttcaaa
    37861 gataaaaaag taaaggaatc agaagaaatt ataccatata gagaggcatt tagaagtcta
    37921 ggcatgaacc caaataaatt tatgagttcg atagaagcaa tgacaacaag ggttgctaag
    37981 aataagaaac ttcctcatat aaatcctatt gtagatttag gaaactctat ttctttaaaa
    38041 tatttacttc caatgggtgc tcatgatatg gattttagaa atgatgatgt atatgttaga
    38101 ttttctaaaa aaggggataa atttgtacca tttggagaaa ctgatgttga attaatggaa
    38161 gaaggagaat taatttattc agttggagac atggtaaaaa ctagaagatg gatatggaga
    38221 caaggagagg aaggaaaaat tactaatagc tcaaaaaata tattttttcc tatagatggt
    38281 tttactgatg ctaatttaga taaggtaatg agtgcaagag aagaattagc aaaattgtta
    38341 aaggaaatat ttaattgtga aattaaagta ggttttgtag ataaagataa tcctgaaatg
    38401 gaaatataat aagttgttga atacttgtta agatattata tttacttaat gatgttaaaa
    38461 aggtattaaa aaagaaaggt cgtagtaaat ttgaaaaaaa ctataataaa gaatgtaaat
    38521 ccaatgattg aaaataagtt tataggactt tttgaaatag agtataaaaa caaattagat
    38581 gaagataagg tttggatggt agcatcaaga aaaagtagtg agcaattaaa aaatatttat
    38641 ttgaagaatg aagaagatag tgtagatgca gttgtaatag ttgggcttca taaaagtagt
    38701 aaaaaattaa ttttaataag acaatttaga gtacctatta atggatatat atacgagtta
    38761 ccagcaggtc ttgttgatga aggagagtct atagatattt ccgttgaaag agaacttaga
    38821 gaagaaacag gacttactct tttagaaatt aaaaaaaata aaagtattga taaagtttat
    38881 ttatctcctg gaatgagtga tgaatctgtt gcctttgttt attgtatatg tgatggtgat
    38941 ataacagatg aatttttaga accagatgaa gagattgaag cgcttttaat ttcgcaagaa
    39001 gatgcaaaag agattttaca aagtaatcat aagatagaca caaaagcatt tttgatttta
    39061 caaatgtttg tgagtttagg agctaaatta tttgaataga tatatagaaa agaggttata
    39121 tagaagagta aaataataaa gtttatttta cttgtataaa ttataatctc tttttttata
    39181 caataaagta taattttgtg tatttttaaa taagtgactt gactcttaaa ttttcataat
    39241 atgttataaa ccaatttaag atactacaat aattaaaatt ccaaaattat ttaacatatt
    39301 tgcaattaaa atgagaaaag gtaaaggttg aatgattgaa aaatttgatg taaaatagta
    39361 gcttagttta atattatagt ttgtagggtt aaaaattaga aattgtaagg gagataaatt
    39421 ctatgaaaaa attagttatt attttaatta gtatcattag tatggttagc ttgacagctt
    39481 gtaaaaaaag caatgaaagt aaatataata atttaaacaa caaagaatcc ggacaaacaa
    39541 ccattgaaat ggacttagat aaaaattatg atacttcaga cccatttgtt aatgcacgtt
    39601 tgttttgtgt gtctaatgat atagatgttt tagacacaga gatttctttt aaaatggatg
    39661 gagatagtgg tattgtggaa ataaaggaca ataaaacata tgaaacttta tggagtaata
    39721 catggcatgg aagcgttgat aatgatacat tcacaatttc tctttctaat atacaaaaag
    39781 agaaagagta tgctatatgc tttactggaa ttaaaataaa tcatgcagtt gtaaaggtta
    39841 cttttgaaag caatttagtt aaggagaaag aaaaaccctc aaaataaatt ccagattgtc
    39901 tataacttga tattcagtac ataaaagcag ttgatattta tgattgactg ctttttctta
    39961 tcaaaaagga gagtttgtgc atttttactt gaaatagttt atgcacatca aaagttggtg
    40021 agcatgatat tggaaatggt aagcatgaaa tcttgataag acaaggaaat aaatttaagt
    40081 tttcaattaa gtatatttcc ataattta
//
LOCUS       DAMJWC010000035        39512 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMJWC010000035 DAMJWC010000000
VERSION     DAMJWC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39512
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.035"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            195..1508
                     /locus_tag="PC503_002061"
     CDS             195..1508
                     /locus_tag="PC503_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2528033.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1680..2855
                     /locus_tag="PC503_002062"
     CDS             1680..2855
                     /locus_tag="PC503_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF2528034.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            2958..3977
                     /gene="hrcA"
                     /locus_tag="PC503_002063"
     CDS             2958..3977
                     /gene="hrcA"
                     /locus_tag="PC503_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF2528035.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            4007..4627
                     /gene="grpE"
                     /locus_tag="PC503_002064"
     CDS             4007..4627
                     /gene="grpE"
                     /locus_tag="PC503_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF2528036.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4719..6566
                     /gene="dnaK"
                     /locus_tag="PC503_002065"
     CDS             4719..6566
                     /gene="dnaK"
                     /locus_tag="PC503_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF2528037.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            6777..7931
                     /gene="dnaJ"
                     /locus_tag="PC503_002066"
     CDS             6777..7931
                     /gene="dnaJ"
                     /locus_tag="PC503_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF2528038.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            8897..9832
                     /locus_tag="PC503_002067"
     CDS             8897..9832
                     /locus_tag="PC503_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2528039.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            9868..11241
                     /locus_tag="PC503_002068"
     CDS             9868..11241
                     /locus_tag="PC503_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528040.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(11429..12196)
                     /locus_tag="PC503_002069"
     CDS             complement(11429..12196)
                     /locus_tag="PC503_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528041.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDFI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12226..13335)
                     /gene="ugpC"
                     /locus_tag="PC503_002070"
     CDS             complement(12226..13335)
                     /gene="ugpC"
                     /locus_tag="PC503_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF2528042.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRNLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            13593..14330
                     /gene="cas6"
                     /locus_tag="PC503_002071"
     CDS             13593..14330
                     /gene="cas6"
                     /locus_tag="PC503_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2528043.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            14335..15810
                     /locus_tag="PC503_002072"
     CDS             14335..15810
                     /locus_tag="PC503_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528044.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENRLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYSFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            15830..16843
                     /locus_tag="PC503_002073"
     CDS             15830..16843
                     /locus_tag="PC503_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HDF2528045.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            16859..17656
                     /gene="cas5"
                     /locus_tag="PC503_002074"
     CDS             16859..17656
                     /gene="cas5"
                     /locus_tag="PC503_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2528046.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            17683..20091
                     /locus_tag="PC503_002075"
     CDS             17683..20091
                     /locus_tag="PC503_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2528047.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            20532..21479
                     /gene="prmA"
                     /locus_tag="PC503_002076"
     CDS             20532..21479
                     /gene="prmA"
                     /locus_tag="PC503_002076"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF2528048.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            21498..22256
                     /locus_tag="PC503_002077"
     CDS             21498..22256
                     /locus_tag="PC503_002077"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF2528049.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEIILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNSVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            22258..23556
                     /gene="mtaB"
                     /locus_tag="PC503_002078"
     CDS             22258..23556
                     /gene="mtaB"
                     /locus_tag="PC503_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF2528050.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            23599..23949
                     /locus_tag="PC503_002079"
     CDS             23599..23949
                     /locus_tag="PC503_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF2528051.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            24112..24291
                     /locus_tag="PC503_002080"
     CDS             24112..24291
                     /locus_tag="PC503_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF2528052.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            24321..24764
                     /locus_tag="PC503_002081"
     CDS             24321..24764
                     /locus_tag="PC503_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF2528053.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            24875..25372
                     /locus_tag="PC503_002082"
     CDS             24875..25372
                     /locus_tag="PC503_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2528054.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            25565..26128
                     /gene="raiA"
                     /locus_tag="PC503_002083"
     CDS             25565..26128
                     /gene="raiA"
                     /locus_tag="PC503_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2528055.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            26341..26577
                     /locus_tag="PC503_002084"
     CDS             26341..26577
                     /locus_tag="PC503_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF2528056.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            26590..27933
                     /gene="yqfD"
                     /locus_tag="PC503_002085"
     CDS             26590..27933
                     /gene="yqfD"
                     /locus_tag="PC503_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF2528057.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            27872..28987
                     /locus_tag="PC503_002086"
     CDS             27872..28987
                     /locus_tag="PC503_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF2528058.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            29044..29505
                     /gene="ybeY"
                     /locus_tag="PC503_002087"
     CDS             29044..29505
                     /gene="ybeY"
                     /locus_tag="PC503_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF2528059.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            29511..30230
                     /locus_tag="PC503_002088"
     CDS             29511..30230
                     /locus_tag="PC503_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF2528060.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            30349..30750
                     /locus_tag="PC503_002089"
     CDS             30349..30750
                     /locus_tag="PC503_002089"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2528061.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            30814..31707
                     /gene="era"
                     /locus_tag="PC503_002090"
     CDS             30814..31707
                     /gene="era"
                     /locus_tag="PC503_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF2528062.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            31719..33098
                     /gene="mgtE"
                     /locus_tag="PC503_002091"
     CDS             31719..33098
                     /gene="mgtE"
                     /locus_tag="PC503_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF2528063.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            33171..33326
                     /locus_tag="PC503_002092"
     CDS             33171..33326
                     /locus_tag="PC503_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF2528064.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            33292..34065
                     /gene="recO"
                     /locus_tag="PC503_002093"
     CDS             33292..34065
                     /gene="recO"
                     /locus_tag="PC503_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF2528065.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            34058..34657
                     /locus_tag="PC503_002094"
     CDS             34058..34657
                     /locus_tag="PC503_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF2528066.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            34817..35695
                     /gene="glyQ"
                     /locus_tag="PC503_002095"
     CDS             34817..35695
                     /gene="glyQ"
                     /locus_tag="PC503_002095"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF2528067.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            35695..37761
                     /locus_tag="PC503_002096"
     CDS             35695..37761
                     /locus_tag="PC503_002096"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF2528068.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(37927..39474)
                     /locus_tag="PC503_002097"
     CDS             complement(37927..39474)
                     /locus_tag="PC503_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF2528069.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEKLFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNKEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
BASE COUNT        15835 a         4088 c         7056 g        12533 t
ORIGIN      
        1 gaataaaata cttatttaga taaaataaat aatttttaga gaatatttta gaagttacga
       61 ttgtatgatt tttaaatgca taggcattta ctctaggact atagactaat ataaaaaaaa
      121 actttgggaa tactaaaacc ataaatttat aaaattaata ttttatatac tgtaaaacag
      181 tgaggaggga cagtatgcat actcaactac aaaagactat tggtctttca gcagctcttt
      241 ctactgttgt aggtatggtt ataggttcgg gagttttttt taagccacaa gcaatataca
      301 ctacaactaa tggagctcca ggtctaggta ttatagcgtg gcttttaggt ggttttataa
      361 caataactgc tgggcttaca gctacagaaa tttcagctgc tataccaaaa actggtggta
      421 tgatgattta tatcgaagaa atatatggag aaaagttagg ttttttaact ggatggatgc
      481 aaactgtatt atttttccca ggtacatcag cggcattagg agtaatattt gctcaacaag
      541 catctgaact tttaggaatg agcccaaata atatggcaaa tgtacttcct atagcaattg
      601 gagttatact atttttagcg ttattaaata taataggttc atccttagga ggaaaagttc
      661 agacagtagc cactattgga aagatgatac ctttaatttt aataatagtc tttggattta
      721 ttaaaggtca aagtagtgaa gtattaaatc catttgtagg agatggtgta aatgcatcaa
      781 atgcacttgg acaagtatta atagctactt tgtttgcata tgatggttgg ataaatgttg
      841 gagctatatc aggagaaatg aagtctccag agaaagattt accaagagca atagttggtg
      901 gtttatcatt agttatggca gtttatatta taataaatat agcttatctt tgggtagtac
      961 cagcaagtga attagcaaca gttacttccc cagctacatt agtagcaaca agattgtttg
     1021 gaaatatagg tggaaaagta ataactgtgg gtatattaat atcagtattt gggacattga
     1081 atggatattt attaacaggt tcaaggatac cttatacatt agctgaaatg ggaactttac
     1141 cagcatctaa aactctttta aaagtaaatt ctggaggttc tcctgtaaat tcaatactac
     1201 ttataactgt gttagcctgt gtatatgcat tatctggtca atttaatctt ttgacagact
     1261 taacaatatt ttcaatatgg gtattttatg tattgacttt tataggtgtt atgaggctta
     1321 gaagacaaaa gccagattta cacagaccat ataaagtccc tttatatcca ataataccaa
     1381 ttatagctat attaggtgga ctgtttgtaa taataaatca aatattgact tcaacagtca
     1441 tatctttagg cggaatattt ataacactat taggtttacc agtttattat tatatgaaaa
     1501 aaagataact acttaattta agttagataa atttgggtaa aggtgaaaat taacttttat
     1561 ccaaattttt tatactgtta tacaatataa gtattatata ttgcttgatg tgctattttg
     1621 tttgatttat aatttagtaa ttgatgtttt aagataattt aagaaatgag gagtgaaaga
     1681 tgctaggact ttatgtacat attccatttt gtgtgaaaaa atgtaagtat tgtgatttta
     1741 attcttataa aatggacata gattcaaaaa aaagatatat agaagactta aaaatagaaa
     1801 tggaattata tagtaataaa ttatataaag ataataaata taaaaataaa gaatgctgta
     1861 gtctaaataa aaatgacaaa ataacgagta tatttgtagg gggaggtaca cctagtatac
     1921 taacctctga tgaaataaga gaagtattta taagtataaa agaaatgttt gatatagatg
     1981 agaatgcaga aataactata gagtgtaatc ctgggacatt aacattagaa aaattaaaaa
     2041 ctatgaaaga gattggcata aatagactta gtatagggct acaagctatt caagaaaagc
     2101 atttgaactt tataggaaga atacatactt atgaagaatt tgagaaaaac tataaagatg
     2161 cattaagtgt aggttttaaa aatattaata tagatttaat gtacagtctt ccaaatcaaa
     2221 ctctatgtga ttggaaggaa actcttgaaa aagttgtaca cttaaatcca acacatatat
     2281 cagcttattc ccttatacta gaagaaggaa ctgaactata caatatgtat gaaagtaata
     2341 aatttgaact tatagatgaa aatgtagata tagaaatgta tgagtataca ataaactatt
     2401 taaagtcaaa aggatataat caatatgaaa tatcaaacta ctcaaaagaa ggctataatt
     2461 gtgagcataa tattttatat tgggaatgtg aacattatat agggattgga gcaggagctt
     2521 ctggctatat taatgagaac agatacaata atgtagaatc tttagaagat tatcatttaa
     2581 gtttggtaaa aagagaaaaa ccaatacaag aaaatgaaat tctttctgag aaagatatga
     2641 tagaagaaaa gatatttatg gggcttagaa tgaataaagg cataaaattt gaagatttta
     2701 aaaaaaaatt tggaatagat tttagagaga agtataataa gcaaatagaa atgctattag
     2761 ctagaaagct tataaatcag agctttgaag gtatacaatt aactcaaaaa ggaagagaaa
     2821 tatctaatag tgtatttata gaatttatgg aataattttt aaggtgttga caaaataaat
     2881 ttataatggt atataatata tataatcttt ttagcactcg aacttagtga gtgctaacag
     2941 ctaggaggta taataatatg gaattaaatg aaagaaaatt aaatatcctc aaagctatag
     3001 ttaaagatta tatagaaaca gctgaagcta taggttctag aacaatatct aaaagacatg
     3061 atttaggtgt tagtgctgct accataagaa atgaaatggc tgaccttgaa gaattagggt
     3121 atttaattca gcctcatact tctgcgggta gagttccatc tgaaaaaggc tataagttat
     3181 atgtaaactc tcttatgagt aaaagcgaat tggatgataa tgataagatt cttattgaac
     3241 aatgtatgaa tcataatata aatcatataa aagaattgat tcatgaaact tctaagctat
     3301 tatcgcaact aacaaactat acaactgtag cagttactaa gagtttaata aatcaaagtg
     3361 ttataaagca catacagttg gttgctatga atgacaataa tattttactt atagttgtaa
     3421 cagataaagg ggacttaaaa aaagctaacc ttacaactaa tgtatattta gatcaatcta
     3481 agttaaattt gatttctgat aatcttacaa ggaagctctt aggtaaaagt ataacagatt
     3541 tggatgataa tctaattgct tttattaaat acgaaataag tgagtattct gggcttatag
     3601 atgagctttt aaatgctttg aactcaaata tgaaagaaga agatttttct ctatcattaa
     3661 atggagctac taacatattt agttatccag aatttaatga tgtattaaaa gcaaagtcat
     3721 ttttaaatat gttggaaaaa aaggaaacaa tagctgacat aattaaatca aagggaatac
     3781 aaaaagacaa tctaaatata ataattggta gtgataatga ttgtgaactg gcacaggatt
     3841 gtagtatagt tacagcaact tataatgtag atagagactt ggttgggcga ataagcttta
     3901 taggccctac cagaatggat tatgctagaa tttactctat aataaattat atgagtttat
     3961 taattaatag aaagtaaaga aattttaaat tgcgaggtgt aaagtcttgg ataaaaaaaa
     4021 tgagcaacag gaagtaagag aagaaaatga tacttctatt aaccaagaat cggaaactca
     4081 agtagagtta gaagaggaag ttgttaatga agaatgtgaa acatcaagtg aaaaaactga
     4141 tgaaaaagaa gttgatgatg aaaatgtaac agatataaat tctaagttag cagaaaaaaa
     4201 attgcaggat gagttggatg aattaaatga taaatatcaa agacttcaag ccgaatatgc
     4261 aaactacaga agaagaactc aacaagagaa agagacaata ggcgtatttg caaatgaaaa
     4321 aataataact gaattgatac cagttataga tagtatggaa agagccttag atgcatgtga
     4381 agataaggaa gatactatgt ataagggtat aagccttgta cataaacaat taatagacac
     4441 tttagtaaaa tttggagtag aagaaataga agcagaatct aaggaatttg accctaatct
     4501 acatctagca gttatgcaag aaagtgtaga tggagttgaa gcaaatcaaa tagtaatggt
     4561 acttcaaaaa ggatataagc taggaactaa agttgtaaga ccttcaatgg ttaaagtttc
     4621 ttgctaagta taaattaaag gttaaattat ttaacctaat ataaaatatt aaaataagta
     4681 aaacttaatt atataattac tcgaggagga ttttagtcat gggaaaaata ataggaatag
     4741 atttaggaac aacaaattca tgtgttgcag tgttagaagg tggagaagca caaataatag
     4801 caaatagtga aggtatgaga actactccat cagtagtagc atttacaaaa gatggtgaaa
     4861 gaatagttgg agaacctgca aaaagacaag cagttacaaa tgcagataaa acaataactt
     4921 ctataaaaac tcatatggga actgattata aagtaaatat agatggaaaa tcatatactc
     4981 cacaagaaat atcagcaata atattacaaa aattaaaatc agatgcagaa agttacttag
     5041 gacaaacagt aacagaagca gttataacag taccagctta ctttacagat gctcaaagac
     5101 aagcaactaa agatgctggt agaatagcag ggcttgatgt taagagaata ataaatgagc
     5161 caacagcagc agctcttgct tatggtatgg ataaattaga ccaagaaaag aaaatattag
     5221 tatttgactt aggtggagga acttttgacg tatctatact tgaaatagga gatggaactt
     5281 ttgaagtttt agctacagct ggtaacaata gattaggtgg agatgacttt gaccaaatag
     5341 taatagatta tttagcagag gaatttaaaa aagctgaagg tgtagattta agaaatgata
     5401 aaatggctct tcaaagatta aaagaagcag cagaaaaggc taagaaagaa ttatcatcaa
     5461 caatgagttc aaacataaac ttacctttca taactgctac agcagaagga ccaaaacact
     5521 taaatataga tttatcaaga gctaaatttg aagaattaac tagaggttta gttgaaaaaa
     5581 ctatggaacc aactaagaca gctttacaag atgcaggact ttctacaggt gatatagatg
     5641 atgtattatt agtaggtggt tctacaagaa taccagcagt acaagaagct gttaagaagt
     5701 ttataggaaa agaacctcat aaaggtataa acccagatga gtgtgttgca gcaggtgctt
     5761 ctatacaagc tggagtttta gcaggggatg ttaaagactt attattacta gatgttactc
     5821 cattatctct tggtatagaa actatgggta atgtaatgac taagataata gaaagaaata
     5881 ctacaatacc aactaagaag tctcaaatat tctcaactgc tgctgataac caaacagctg
     5941 ttgatataca tgttcttcaa ggtgaaagaa gtatggctta tgacaataca actttaggaa
     6001 gattccaatt aacagatata ccaccagcac aaagaggaat acctcaaata gaagttactt
     6061 ttgatataga tgcaaatggt atagttaatg tttcagctaa agatttaggt acaggaaaag
     6121 agcaaaaaat aactataaca tcaaacacta atttatcaga agcagaaata gagcaaaaga
     6181 taaaagaagc agaaatgaat gcagaagctg acaaacaaaa gaaagaaaaa atagaagcat
     6241 tcaatcaagc tgaatctact atatatcaaa ctgaaaaaac tttaaatgaa cttggagata
     6301 aaataagttc aggtgaaaaa gaggatatag aaaaagctat agcagactta aaagctgtaa
     6361 aagataatca agatgctaca gcagaagaac ttaagaaagc tacagatgaa gtaatgacta
     6421 agttccaaaa agtatctcaa gaaatgtacc aaaaagcagc tcaagaacaa caagcggcac
     6481 aaggtgcaga acaagcacaa gacaatggac ctaaagatga caatgtagta gatgctgact
     6541 ttaaagaagt agatgaagat aaataagcta tataatatgt aacactaaat gataattgga
     6601 acatatatga tttgtgaaaa tcatatagat gttaaagata tatggacaat atacatcata
     6661 aagaatataa tatatcatag attatataac ttaaagtaga atataagaat taatgatagc
     6721 ttgtagttta ttattctaca agctatcgtt ttgtaaaatg aaggtggtgt caatttttga
     6781 gtacaaaaag ggattattat gaagtcttag gtatcagtaa aggtgcagaa gctcaagaga
     6841 taaaaaaagc ttatagaaaa ttagcaatga agtaccatcc agatagaaat cctggagata
     6901 aagaggcgga agaaaaattt aaagagataa atgaagctta tgaagttcta tctgatgata
     6961 caaagagaaa aacttatgac cagtttggac atgatgggct aaatggtcaa ggcggttttg
     7021 gtggtcaagg aggatttggc ggtcaaggct ttggtggttt tgaagatatg ttcggagata
     7081 tatttggtga catgtttgga ggaagcttcg gaggtggaag agcaagaaga agagggcctc
     7141 aacgtggtgc agatataaga cagagtgtta ctatatcttt tgaagaagct gcatttggta
     7201 aaaagatgtc tataaaagta aatagaagtg aagaatgtga agaatgtaat ggaactggag
     7261 caaaaccagg aacatcaaag aaaacttgtt caacttgtaa tggaactggt caagttagaa
     7321 ctgttcaaag aactccattt ggtaatatag caagttcaag accatgtagt gcttgtaatg
     7381 gaactggaga agtgattgaa tctccatgta gtaaatgtca tggaactgga aatacaagaa
     7441 aagttaagac tatagaagta gatatacctg ctggtataga tgatggtcaa atgataaaac
     7501 tttctggtca aggtgaagta ggagaaaaag gtgctccaag aggagactta tatattgtag
     7561 ttaatgttaa gtcacatcca ctatttacta gagatggaaa tgatatttat tttgaaatgc
     7621 caattacatt tgttcaagca actttaggtg atgagataga agtacctact ttggatggaa
     7681 aagttaaata tagtgtgcca gaggggacac aaactggaac tgtatttaga cttaaagaga
     7741 aaggaatccc tagaattaga ggtaattcaa gaggagacca atatgttaag gttgtagttg
     7801 aaattcctaa aaaattaaac gataagcaaa aagaactatt gagagaattt gcgaaggagt
     7861 gtgggtcgaa cgtccacgaa aagaagaaaa ccttcggaca aaagatagaa gatatgttta
     7921 agaaaaagta gttaaagtag ccaatatata atcatatttt taaaatctta gttatttata
     7981 agattgtcaa aggagatatt atgattttta tattggctat ttttgtataa aaaataaatg
     8041 tgcataaaat aaaactgaat ataaataatt ttctgaaaaa tacttgtcct aaaatatata
     8101 atatgctata atataatcaa ataaaagaaa ggggtgattc cagtgggaac ggatgtggca
     8161 ctgccaaatg atgaagaaaa ctttattgta atatacaaaa taaaattaga tacttttagt
     8221 gctagattaa gtactggaaa aactcatgag ctgggataat tattgtaatt acctagactc
     8281 aaacttttag tagtaaaata gtaatattat atagacaagg tatctaattt ttaaatcttt
     8341 tgtatgaatt aaaattttta taaagggtat atctgattag aatgtaatta gggaaaccta
     8401 gttgtgaatt acttttagta tatacatgtg taaagaaata tgtatatggt attggttatt
     8461 gtgctagatg tgtatgtaaa ggaatatgtg tctagttggg tatatgtaaa gaaatatact
     8521 tataatctat gaaaaatttt tagtataaat tgctaaaaca ttgagattgt tttttataga
     8581 aagttagttt ataccaacta aaaatgtgct taagatttgt ttgatgttta attataaata
     8641 aggttgtaga taaaaaaata agtaaagaca aaggtttaaa atacttgctt taaatatagt
     8701 ttgttttgaa cacttgccaa attaaaataa ttaataaaat agacatcttc tcatagtaaa
     8761 atatactgtg agaggatgtt tttgctttgt tcataaactt ttatgaaaaa tttgcatagt
     8821 gtcacatttt aatatactat atatataata aaatatagat aaaattaaat gattcaaaag
     8881 agaaaggtga aaagagatgt attatatagg tgtagacata ggaggaacag gtatacaagc
     8941 aggagtagtt gataactatg ggaaaataat ttttaggtca gagtgtaaaa cagtaattga
     9001 aaaaggcttt gaaggaatac ttaatgacat aaaaataatg atttataagt tgttggaaga
     9061 taataaactt actatgagtg acataaaatc tattggattt ggtgttccag gttttataaa
     9121 taaagaagga ttagtaactt gtgtaaattt aaaatggaat aaaaaagctt ttaataaaga
     9181 gttaaaaaga agatttccag atgttgaaat tcatggagaa aatgatgcaa cagtagcagc
     9241 acttggagaa gcaaagtttg gaagtatgaa aggtgctaat gttggagtat tatatacttt
     9301 aggaactgga gtaggtggag gaatagtaat taatcaaaaa gtcttttctg gagcacatgg
     9361 attgggttca gaaataggtc atcaaattat aggagaaaac tattttaatt gtaattgtgg
     9421 aaataatggt tgtgtagaaa ctttttgttc agcaactgca attataaagt attctcaaaa
     9481 actgatagaa gaaggagaaa agagtaggat tttagatttg gcagagggaa atttagaaaa
     9541 tgtaaatgca aagatggtgt ttgatgcata tagagaaaat gatttagtgg caattaaagt
     9601 aataaataga tttaaagagt atttagcaaa aacttttgca aacacaataa attctttaga
     9661 cccagaaatt atatctatag gaggaggcat ttctaaatct agcgatataa tacttgatgg
     9721 aatagaagat ttggtaagaa aatttgtatt atacaaaaca gaagatatag ctacaattac
     9781 atgtgcaact ttaggttcag acgcaggaat tataggagca gcttttttat aatgtaaatg
     9841 aactgcttat tggaggcgtg atgatatatg ggtaaaacaa atgctagaag aacgcttttt
     9901 ttgatagcaa taggttcagg aactatgctg aatcctctta attcttctat gatttcactt
     9961 gctttacata gtatacaaaa tgattttcat attagtttta caactgtatc ttggattgtt
    10021 tcagcatttt acctagctag tgctattgca caaccagttt caggtaagat aggagattta
    10081 ataggtagaa aggtcttatt tttgagtggt ttgatgcttg taattttatc agcatccata
    10141 gtaccacttg ttcaatcatt ctttatattg atttttataa gagtaattca agcaattgga
    10201 acaagtaccc tatatccatc tggagttgct cttatacaaa ataatataaa agaaagacaa
    10261 tcttctgcat tagcagttct aaccattttt gcttcaacta cagcaggatt aggtccgaca
    10321 cttggaggat tattgttgga cttaggagga tggcatgcta tatttcttgt aaatatacct
    10381 gttgttttgg tttctatatg cttagggtat tttttattcc caaaagaagt aaaagaaaag
    10441 aaatctataa aagaaacttt aaaaaatgtt ttgtcaagat tagatattat tggcatactt
    10501 ctattttcaa ttgcaatgat ttttatatta ctatttttgc tatctatgaa ggagtctttt
    10561 aacttggaac aacttgtatt tggtataata ctgatgtgtc tttttatttg gcatgaattg
    10621 agaacaaaat tgccatttat agatattaag ctttttgtaa gtaatcctaa attgtcaaaa
    10681 gtttacttgc aatttattat attaaatttc tttaattata ttttgttttt tggtcttcct
    10741 agttattttc aagatgcctt acattatagt gcaaagtcga ctggattatt tatgctattt
    10801 atgtctggta taggtatatt tatatctcca ttaactggaa aatggataga taaatctgga
    10861 actagatttc ctcttgttac atcatcaatc tttatgttta ttagtgcagt acttctttca
    10921 gtagttttta tccatatacc tgtaatagga aagggtatta tattatcatt agcaggtatt
    10981 agttatggag ttggtaatgt agccctgcaa tcctctatgt ttgaagaaag tcctcgtgac
    11041 agtataggga cagcttctgg tctgtttcaa actagtcgtt atttaggttc tattttagca
    11101 actgttttac ttggaatggt atttgaagta aatataacat cagaacaatt tcagatatta
    11161 ggttatgtta tggtggtctt aggtacaata agttttttat taaattttat attaaagaaa
    11221 gaattaagaa aagtagaata gtggatttat ggatttaata agtctaataa ctgataagtt
    11281 taaaaatatt gtttgtaaaa cataactggt ttgatattta ttaattctaa gttttgaagc
    11341 atagagtact cgataagtat acaatatttt gaattaaaat taagcagaaa tttgaactag
    11401 tctttcaaat ctctgcttaa tttagtagtt aaattttttt atagagaaaa taagatttga
    11461 cacttagata aaaaatcatt gcattttcaa aattctttaa atcaaaccca agtatctcat
    11521 taatcttttc caatctatat actagcgtgt ttctatgtaa aaacatacta gtagatgtct
    11581 tagaaatatt taaatcatta tttataaatt ttattcctgt atatagaagt tcttcgtcaa
    11641 tagatttaat cttattaaaa tctattaatt tattgagtat attatcctca ttaattaaat
    11701 ctaaagtttt atatctaata aagtcaaaca aatttaaaaa cttattttca gcgttgtctt
    11761 ttataatatg aggtagtaaa tcagaacata actgtaatct aaaatcaaaa tcagctttac
    11821 tatctaattc accaagataa aaaatataag tactttgata agtttcagtt tcaattatat
    11881 tttgtgtagt tacattaata tctaagttat atttagaatt tactataaaa aaaccattgt
    11941 gttgtattat atttatatct tcaaataaat tataaaaaat attttttaga tattcaaagt
    12001 ctatatgaga ttggtaaatt aaataaaagt tgccttttaa attatcgaga ttatttttat
    12061 ctagaaaatc aataacataa atagcattat tgaaagtaac taaatggcta ctagcatcta
    12121 acttttggtt ttcatatgga tagatattta tttttttatt aagctgtctt tctaaaaaat
    12181 cttttaactc ttccataaag tctccttaaa aataagatta tattcttatc ttatagctaa
    12241 agtagtttct ttgtcaaata tgtgtactct actattgtca actgaaagtg ttaagtcatc
    12301 accaacatta attctgtttt tactgtcaaa tctaattgtt atcgtatttt cgcctagttt
    12361 taagtgagca taagtttctg ctcccataag ttcttttatt tcaattcttg atttaaaaca
    12421 agtatctgga ttagatttaa taaaagtatc ttctacatga atatcttctg gtctgatacc
    12481 tataacaact tcattattaa tataattgtc ttttattaaa tcatagtgtt tttctttatt
    12541 caatttaagc ttaatatgtt cattttgtgc ataaatttca tcattttctt ctattaatat
    12601 tacatcaata aaattcatct gtggtgctcc aataaatcct gcaacaaata tattagctgg
    12661 ataatcgtat acatcttgtg gagttgcaat ctgctgaact actccatcct tcattactac
    12721 gattctatca gccatagtca tagcttcaac ttggtcgtgt gttacataga taaatgtagt
    12781 tccaagctgt tggtgtagct tagttatctc tgttctcata gcagttctaa gttttgcatc
    12841 taagttggat agaggttcat ccattaagaa taccttagga tttctaacta ttgcacgtcc
    12901 taaggcaacc ctttgtcttt gtcctccaga taatgtttta ggttttttat ttaaaagagg
    12961 tagtaagtct aatattttag cagcttcttt aacttttttg tctatttcat ctttaggcaa
    13021 atttctaagt ttaagtgcaa atgccatgtt ttcgtaaaca gataagtggg gatataaagc
    13081 atagttttga aaaaccatag ctatatctct atcttttggt tctatattat tgacaagttt
    13141 atctccaatg tatagttctc cttcagagat ttcttcaaga ccagcaatca ttctaagtgt
    13201 agtcgattta ccacaaccag atggtcctac taaaacgata aattctttat ctttaatgtc
    13261 tatatttata ttttttactg cgttaaatcc atttgagtaa agttttgata tattttttaa
    13321 aattacttct gacataatat cctccttgat atttaaattt taattatata gtatcaaatt
    13381 tttttattat attaaatgtg taaaatgact aaatgtattt gtttaatatg tatatttagt
    13441 ttttagcaaa gaataaaact aacagtagaa tatatttaaa aaattaaaaa acaaaattaa
    13501 atttattatc aaaaaatcat tttatgatat gttttatttt tatattacaa atagagaata
    13561 atgaattata ctagaaagta ggaggtgaaa atatgagcag aatttcaatt tttatggaat
    13621 catgtaatgg caaatttcca aatgaaaatt caatgttgtc agtttccttt ataaaaaata
    13681 ttttaaatgc agaaaacaaa gattttgcta aaaacatatt taactatggg gaagaaagaa
    13741 aaaacaataa gcaaataaag gatataaata cagccattta cataccaaat cttataagaa
    13801 gcaaaaatga gttacttgtt gatggagata taatattcaa tataagtttt tataattatt
    13861 ctatgttcag taaattatac aatggaattt taaaagtaaa ggagctagaa tataaaggtt
    13921 atagatttaa aataaaaaat ataaaaatac ataaagaaca cgagataaaa gaaaatggtg
    13981 ttatatttaa aactatgtct cctataatag taaagaataa agaaggtaaa tatttagatg
    14041 tagaagattc aaattatata gaatgtttaa actatatagc taatctaact ctggagagta
    14101 taagaggtag tgggcttaga aagccattgg aatttatacc tattaacttc aaaaaaagag
    14161 tgttaaaaga aaagattcgt ggatttaaag tgagagaata ttactatata aatgcttatg
    14221 caggaacatt ttttttaaaa ggagatatgg aagatttaaa tgcactgtat aaaatgggaa
    14281 ttggatatag aaggacagaa aatgcaggaa tggttgatat attaaagtag cgaggtgaga
    14341 gaaataaaag ctaaatttta tagatcaggt gatattgtaa gagatattgg cattgtttac
    14401 ttttatgaat tactaatgga tttaaaaaac gaactagaaa aaaatgatta taagctaaaa
    14461 tttacttgtg agttaaatag aaattattta tctttagaat ctgcagaata tatagaccct
    14521 aagtatatat ctgattatat attagaaaat cgacttttta aggtatttaa aaatgggaaa
    14581 aaggaaacct tagaaaaaat atttagtaat atagataatt taacgtatgt aaattttatt
    14641 gaagaattag ataaatcttc tgcaactgct aaacaaaagg aagatattaa aaaagatttt
    14701 aaaaacagga ggtttccata tgttagaaat agtggtaagt atggattaaa cacgagttta
    14761 gaaaatatgg aaacaaatgt aaaaagaata gtagatactg taattaaatc aaatatagag
    14821 atagatgaaa tagataaact tgatttgaca caatatgaag aaaaagatag tgtatgtaat
    14881 gtttgcaata taaataaaac aacaaaacta gatattgatt taagagaacg aaaggactct
    14941 aagtataact ttttatttag aggtgcagaa aaatcaggct ttaaaagaag tggacaagtt
    15001 gaaagtaata tttgttttga gtgtgaattt ttcaacttaa tgtgtctttt atatataaat
    15061 ttaaaaagac caatggtttt tgcatatacg aatgatttaa gagaattagc atttttaaat
    15121 cataagataa tgcttaaaag aaaaatgtat tcagataaat cattttataa aaaacttttg
    15181 catgaaaaaa taagttcaat tagactatat agctttgata ttgatacgaa taaaggtata
    15241 attctaaagt ttgattctat tatagagtat aaagaattat taaaaaaaat tgaacttata
    15301 gatattatag ataattataa tttttcaaga gagccaggta atactagaaa tttgggtaaa
    15361 agaatgattg ataatgggaa tttatcaaat ttaaaagaat tattacttga taatataagt
    15421 gttttaaagc aatcaactgg aacttctcga gaaatggatt ttgtatctag ctcatataat
    15481 atcggtttat atataaaatt gtgttggatt gtagatggag gggaggagta taaaatgaaa
    15541 aactatatgg aaagtaattt aatatattca agagtaggta aagacttatt taataaaatg
    15601 acagatgaat ccagaagaaa aaatttttct atgaaagtga ttcaactact taagtctaat
    15661 gatagaactc agctatttca aactataatg catgtgttag tttctaatgg aatcttaata
    15721 ggagaagggt ttgtagaagg tctaatgcag agttctgaat tagaattaaa tacgaatgta
    15781 ggtctattta ttcaagaaat catgaaataa aaaaggggga aaatttaaaa tgaatgaaaa
    15841 aagagtaaaa ggagtaacat taactatact gacagaaagc ccagttccac tttcatatga
    15901 ccaagggtat ggaaattata caccaataaa aaaagaacaa tatagagaaa aaatacatgc
    15961 aaaaactagt atagccacaa taacatatga tttaagaaga atgctccacc aagaatatgg
    16021 ttggaattta agtaatattg tttttggaaa aaaaggaaat atatatccat ctattaagaa
    16081 aaatgtagga tgtgtagatg aaaatggatt agagactgat gtatttggtt atttaatacc
    16141 acttaaagat aaaggttcta taagtaaagc ttctccactt agaataatac cttttaggtc
    16201 attaaatcca tataaaggtt caacacagct aataacaaat agaggctttt taagtagtga
    16261 atttggtaga aaatattatg atgagaagga agaaaatgaa gtacctagag atgaaaactt
    16321 tccaacatca caagcattag caatagaaga gactttatca gattactacg tttatacaat
    16381 aacattggag cttgatagaa taggagtagt agaagtagaa gatggaaagt tacttttacc
    16441 agaagaaaga aaatttatga gtaaggagtt aagagaaaaa gcagtaaaag atatattaga
    16501 tgcaattact gtgtttacaa gaaacataaa acattcatca gtactattaa aaccacttgc
    16561 agtaataggt ggagcttttg ataaagttgt accatttttt tgggatgatg tagattataa
    16621 tgctgatagt ggtgagataa atttagaggg agtcatagaa actatagaaa gttatagcct
    16681 taaagaaagt aacacaatac ttgctatcaa tgatagatta aaaatttcta ataaaaagga
    16741 attaaataag tttaatttaa gtaaataccc tgtaaaagag attaaaaatc tagcagatag
    16801 attggaaatt ggagaagata atatgtggta tttaaaagag taggaggttt tttgaattat
    16861 gaaagtatta caatgtaaac ttaagcaacc aactgctcac tatagagacc caaaagtatt
    16921 tcaaaatgaa tatataagta ctttaaattt accatctaag accacaataa tgggaatgat
    16981 aacgtattta tgtgatagaa gattaaactc tgatatagat ataggaataa ttggaacaca
    17041 tcatcataga gaactagaat tttcaagagg agaaaacatt gatttttgga atgaatatat
    17101 aaaaatggga aaaggtaaag ataaagaaaa gtttttgctt aaaggaaact actatgatta
    17161 ctataaagag cataaagctc aaaatagcat attaaactat gaagttctta aagaagtaga
    17221 actgactata tttatttctt gcaaggatga tgaagaactt gaatttatta gaaaaaagct
    17281 tgaaagtcca tgtaaatatg caaatttagg aagaaaagaa gattttgtaa taccaagtga
    17341 aaaagggtgt tttgtgaaag aagttaagtt aaaagaggtt atacctatga atactcgtga
    17401 tgctataaaa gaaaatataa aattaaagaa tacatatgta agagttgact taagagataa
    17461 agagaatgtc gagactataa taaatcaagg tgtattgatt gcattgcctc ataaatataa
    17521 agatttagaa gcaaatagag atgatagagt ttatgagttt tgccattata tatatgttga
    17581 taatgatggt atatatccta aaaatattaa ggtaaatgta tgtattgata caaaagaagt
    17641 ttttacatgg ctttaaatta ttttgaaaga taggtgttta tcatgaaaaa tatcatgcaa
    17701 aaagaaatat tagctaagtc atacaattta agaactaatc aacaagaaca aacattagtt
    17761 gaacatatta aggatttatt tgaagtatta gaatctatat tagaattaaa tctatattca
    17821 gataaagatg tagagatact aaaaatatgt tgtgctttgc acgatttagg aaaaattaat
    17881 tcaattatgc aacaaaaaat ggagattaat aataaaatat cgtatagttg ctcagaagaa
    17941 gagaggaaaa agttagagtc tgacaaaaaa tctttaaaaa agatagcaag acataatata
    18001 ttttctggag catttttaaa agatatatta gaaaaaatga acttgtcaga agaagataag
    18061 ttatatatat ataaaagtat aatgttacat catggaaact atgaagatta tatgaggtta
    18121 agtattagta aagttcaaga agaaatttat gagtatattg aaaaaggcat tttagaaaaa
    18181 gaagagttta atctgaaaga tatagaaagt tatataaata gcattttaaa tgtagacttt
    18241 aaatttggtg aagatgtatt ggattatgat tacatagata aattaagtga aagtatgttt
    18301 atagacagtg attataacaa tggtcaaata gatgattcag ttttaaatta tagaaagttt
    18361 aagtatattt tatataaagg gatgctgaac ttaatagacc atagtgcatc aagtagacag
    18421 aaaggtataa aattttataa cgattttact gatgaagaaa ttgataatat gattttaaat
    18481 gagatatata agagtcaggg taatttggaa aaaaataata tagagttcaa tactatacaa
    18541 aaaaggttga gagaactttc tggaagaaat gttctgactg ttgcatttac aggttcagga
    18601 aaaacagctg cagattatag aaagactttt aaaagaaaat tctttttagt gccaaataaa
    18661 atatcagcag aaagttttta tagaaaaaat atttttcaaa ataaaaatga tttagataca
    18721 agaagtagta atgattacat tggattactt catggagata taaacttata ttcagagaat
    18781 gaagataatg gagaacatga ttttgtattg acattaaggg atatagattt gagtataaac
    18841 ttttgcaaac cttgtgtaat tgcaacagtt gatcagttat tacttagtat gtttaaattt
    18901 ccgggatatg aaaaaatatt cgcagccgta aaaaatgcat ctataactgt tgatgaagta
    18961 catttattgg aaccaaagat gtttttgatt ttgatatatt ttatgcagtt tgcatgcaag
    19021 tacttagatg ttgattttca cttaatgaca gctacacttc caaaatcata taaagagcaa
    19081 atgataaaca agggaattat ttttcaagaa gaaagtaatg aaaatgttac tgataaagga
    19141 gaaatagttt ttattgagag caacaaggaa gaagagattt gtgaaggtaa agatgtaaag
    19201 gtttctttta taaaggaaaa agaaatcaag tcaatagttg aagatgcttt agaaaataaa
    19261 caaaaaattc ttataataaa gaatactatt gattcagtca atagaacata tgagttttta
    19321 aaagaaaatt tatctgataa gtatggtggt gtagatatag atgttttaca tagtagattt
    19381 aagttcaaag ataaaaaaga gaaatatagt aaaatattaa atggagaggg tgatatttgg
    19441 atatcaactc aatcagtaga aatatccttg gatttggatt tcaatataat aataagtgat
    19501 ttagcaacta tggatagctt aatacaaaga atgggtagat gcaatagaaa taataagtat
    19561 gaatatggaa acttttatat tctacctagt gaagataaaa tttatgacaa caaacttaag
    19621 agcacaacta aaaacatctt aaaggacata ttaaaaacta actctatttt tacaatggga
    19681 attagaaaaa ctattttgga tgattactat gataatagtg tagtcaaaaa atattttgaa
    19741 gagaatttta taagttgtga taaagaaatt aagaatattt atggtgtaaa taaagaaatt
    19801 tttgatggat tggatttaat ttttaatttt gaaccttaca aaaatattgt tgatagtaag
    19861 aaggaagcag ctaaaatttt tagagatgtt gatgttagtt acaaaattat tctggaagaa
    19921 gatttttata aggaagatag agagttacaa caagattcga ttcaagtatc agggtttata
    19981 tttaatagat tatattatta tgggttaata agcaaagtag aaggatacat ggtactaaaa
    20041 tctagtagta agtttgagta taatagtact gtaggcttaa ttttgaagtg agcatatgtt
    20101 taaatataat atacctttag acattgaaaa tacaaaaagt actactgtaa gctcactgta
    20161 aaaactattt tttaaaagga aaaataagtt gtgagataga gtgtttacaa gtgtatatag
    20221 ataataaatt tgaggtttaa gattaactaa gtgggtttca ggtacatcgc gaaaataatt
    20281 ataagttgga gattttgtat gtttaagatt aactaagtgg atttcaaata ttgatatagt
    20341 agatataata gaagttttat tattaggttt aaaattaact aatcggattt ttaaatattc
    20401 tgactattat ataaggatat tattagattg aatttaaaac caataatata aaacaacaaa
    20461 atattatatt tatgatataa taaaagttat ggaaaaacag gaatattact atagagaaga
    20521 gaggtaaact tatgaataat tggatagaag taactataaa aacaacaaca gaagcagttg
    20581 aacctataac gaatatacta tatgaacaag gagctggagg agctgtaata gaagacccaa
    20641 aagacttttt attccaaaag aaaaatgaac tagactggga ttatgttgaa gaagaagtat
    20701 ttaaaaagaa tgaagaagat gatgttctta taaaaactta tgtttctgaa gaaaaaaatg
    20761 tgatggaatt tgtcgaaata ataaagcaaa aagttttagg attaaaagat tttggtatag
    20821 atataggtga aggaagtgta tcattggacc aagtaaatga agctgattgg gcaaatgcat
    20881 ggaaagcata ctacaaacca acaaaagtag gacaaagggt agtagtaaag cctacatggg
    20941 aagattatgc tatgcaagag ggggatttaa tcatagagct tgaccctgga atggcatttg
    21001 gtacaggtac acatgagact actagtatgt gcattagaga attagaaaag tatgtgaata
    21061 aagattctaa agtatttgat attggatgtg gtagtggaat ccttgcaata gcagcagcta
    21121 aattaggagc aaaagaagtt gtagctgtag atttagatga agtggctgta aaagttgcaa
    21181 aagaaaatgt tcttgaaaat aaagttgaaa aaagtgtatc tgtaatgcat ggtaatttaa
    21241 ctgatgtaat aaaagataaa gcggatgtaa tagttgcaaa tataatagct gatataataa
    21301 agatacttgc aaaagatgtt caaaacttta tgaaagaaga tgctatattc atatcttcag
    21361 gtataatttt ggataaagta gaagaagtta aagaaagctt aattgaaaat ggatttgaaa
    21421 tagttgaagt tcaaaaatta ggtgaatggt cagcaatagt ttctaagctt aaaaaataag
    21481 ggatatggtg acgtataatg gatagatttt ttgttgaaaa aaataatata aatctacaag
    21541 ataaaacttg cactatagaa ggtgaagatg taaaacatat ttcaaaagtt ttaagatgca
    21601 aattaggtga gaaacttgaa atatgtgaca agaataataa tgagtatatt tgtgagataa
    21661 tgaatataga taagagtata gttaatttag aaattttaga aaaagttgat ataaatagag
    21721 aatcagaact taaagtaagg ctataccagg gacttccaaa agctccaaaa atggaaataa
    21781 tacttcaaaa attaactgaa gtgggtgtag aagaaataat attagttcaa actaagagaa
    21841 gtgttgttaa agttgatgac aaaaaagaag ataaaaaatt tgaacgttgg gaaagaataa
    21901 tttatgaagc agcaaagcaa agcaaaagag gtaagatacc aaaattaaga ggtgttttaa
    21961 gttttaaaga agctttagaa gatatgaaaa aaaatagtgt aaatatttgc ccttatgaaa
    22021 atgaaagaac agtttcaata aaacatgcac taaaaaaatg tgattctaat atagatagtg
    22081 ttggaatttt tataggtcca gaaggtggat tttctgaaga agaaatagaa caaatacaaa
    22141 aaaataattg taatgttgta tcattggggc ctagaatatt aagaactgag acagcttctg
    22201 ttgtagcatc aacaatagct ttgtatgaac taagtgattt aggaggagaa aaataaattg
    22261 aaaaaagtag ctttttatac acttgggtgt aaagttaatc aatatgaaac agaagctatg
    22321 ctagaactat ttgagaaaga tggttatgaa caagtcaata gtgaagagta tgctgatgtt
    22381 tatgttataa atacatgtac agttactcat atgagtgata gaaaatctcg tcaatatata
    22441 agacgagtta aaaagaagaa tccagatgca ataatagccg ttgtaggatg ttattctcag
    22501 gtatctccgg aagaaatttt ggatatagaa gaagtaaatt tagtcatggg tacaaatgat
    22561 agaagaaaga ttgttgaaga aattaaaaag ataaattcaa gtaagaaagt tagtacagtt
    22621 gatgacataa tgaaagttaa agcttttgaa gaaatagaaa tcagccaaac taatggaaag
    22681 actagagcat ttatgaaaat acaagatgga tgtgacagat tttgtactta ttgtatcatt
    22741 ccttatgccc gaggacgcgt tagaagtaga gatattgata gtatagtcga tgaagttaaa
    22801 aaattggcta ataatggcta taaagaggtt gtattaacag gaatacatgt tgcctcttat
    22861 ggaaaagatt taaaggatag ggatattaaa cttcttgatg taataaaaca aataaaccag
    22921 atagaaaaaa tagaaagaat taggcttagt tctgttgaac caattttatt tacagatgaa
    22981 tttgtaaatg aagttttaaa gatggataaa gtttgtcctc attaccattt atcacttcaa
    23041 agtggatgtg atgaaactct aaaaagaatg aatagacgat acacaacttt agagtacaaa
    23101 actattgtag atagattgag aagtaaaatg ccagatgtgg caataactac agatgtaata
    23161 gtaggttttc ctggagagac aaatgaagag tttaaaaaaa cgtacgagtt tttaaaagaa
    23221 atagagcttt cacaaatgca tatttttaaa tattcaccaa gaaaaggaac tccagctgca
    23281 actatggaaa atcaagttga ccctcaaatg aaacacttta gaagtgaaca acttttaaat
    23341 ttaagtaaag taaattttaa taaatttgca actaaattta tcggccgtga gttggatgtt
    23401 ttatttgaac aaaatataga aggcaataaa tatgagggat taacttcaaa ttatataaga
    23461 gttgttgttg aaagtgacaa aaatatacaa ggtcagatat taaaagtgaa aataaatgat
    23521 gtaaaagatg aatatgtaga aggaattttg ctataacatg tagaaattat aatatttata
    23581 agataggagg tggaaagaat ggattgtatt ttttgtaaaa tagcgaacgg agaaatacct
    23641 tcaactaaag tttatgaaga tgatagagtc ttagctttta atgacttgaa cccagttgct
    23701 ccatatcata tattagttgt acctaaaaaa cattatgata gtttaattga tattcctgat
    23761 aaagagatgg acattgtgtc acatattcat gttgttatta ataaaatagc taaagagaaa
    23821 ggttttgacc aaactggatt cagagtcata aataattgtg gaagtgatgg agggcaagaa
    23881 gttaaacatt tgcactatca tattttagct ggtaaaaagc ttcctaatta cgaagcggga
    23941 caaaactaaa ctaaattatt gaaaaattga gttccttctt gataaaaata cttgataaaa
    24001 gtaaaaattt agtttataat aaacaaagtg ttaggttgta atgcatatta tgcaaaaaga
    24061 acatagttac agtcccagca taattgcgct attggaggga gggaaaaaga aatgtcagaa
    24121 gtaagagtta gagagaatga aacattagac agcgctttaa gaagattcaa gcgtcaatgt
    24181 gcaatgtctg gcatcatgtc agaagtgaga aaaagagagc actatgataa gccaagcgtt
    24241 aagcgtaaga aaaaagctga agcagcaaga agaaaaaacg ctaagaaata gtagtaaata
    24301 agaataaaga ggtgaagggg atgtccctta agcaaaagtt acaagaggat ttgaaatctt
    24361 cgatgaaaaa caaagataca gtgagaaaat ctgtagtaac tttaataaga gcttctataa
    24421 agcagtatga ggttgataat agggtcgagc ttgatgaaga tggaattatc gatgtaatag
    24481 caaaacaatt aaagcaacgt agagatgcat tagttgaatt tgaaaaagct ggaagagaag
    24541 acttaataaa agaaacagaa ggtgaaattg aagttttaaa agagtaccta cctcaacaat
    24601 taagcgaaga agagttagaa gaaattgtaa aatctactat atccgaagta ggggcaactt
    24661 ctatgaagga tatgggaaaa ataatgtcag ttatccaacc aaaagttaaa ggaagagctg
    24721 acggaaaact tataaataag ttggtaaaac aaaacttaca atagattgat atagcctaga
    24781 gagaaatctc taggcttttt atagtttttg ggaataacga gtcatatttg agcatatcta
    24841 taatcaaaga aaattttgaa agaaggggaa aaatttgatt atatcagtaa aagagattag
    24901 gaattttttg ataaacatat ttataccact aataataggt tacttaagta gcatcttaac
    24961 aatgattatc agtggaacag atatttcaac ctattattta caactcacaa agccaagctt
    25021 tgcaccacca gcttttatct ttcctatagt ttggactata ttgtacatat tgatgggtat
    25081 atcttcatac ctaatattaa gaaagggtta caacttacct aaagtaagag atgcaatttt
    25141 ttattatgga ttacaacttg tattaaactt tatttggagt atactatttt ttggatttgg
    25201 acttagattt acagctttga tagatataat aataatgatt ttggtttcta taataatgat
    25261 ttcgaagttt tctaaaatag ataagagatc tggatacata aatttgattt atttaatgtg
    25321 gcttgtttat gcaggatttt tgaactattt tatatggttt attaataaat agaatgtaaa
    25381 gattttgtaa attaccctgt acttttaata atatcataac aaacgaaaaa taaatagact
    25441 attaaaaata atcattttca tatacaataa tattaattta aatacaataa atttataaaa
    25501 attgtattta aagattaaca tattaaagta ttagaattgg aaaggcttga agggagaggt
    25561 ttttatgcaa ataatagtat ctgggagaca aatgaaatta actgacggaa taaaaggata
    25621 cgtagatgga aaattaagta ggttagaaaa ataccttgat cctgaatcag aagtgaaagt
    25681 aacagtaagt gcgaaaaagg atagacaaaa agtggaggtt acaataattc ctattaacgg
    25741 tcaaataata agagcagaag atgtagaaga tgacttatat gcagcaattg atattgtttg
    25801 tgacaaatta agtagacaag ttgtcaaata taaaactaaa gttaaagaca aagttcaaaa
    25861 taataagagc ataagatttg aaaatcttga ctttatagat aatagcagtg aatttgatga
    25921 ttatgattat gatgatgaag aagatgaaaa tatagtaata gaaagaagaa agaaatttaa
    25981 tgtaaaacct atgagttctg aggaggcgat acttcaaatg gaactagtag gacacaattt
    26041 ctatatgttt agaaaccaag ataattttga aataaacata gtgtataagc gtaaagctgg
    26101 tggatatggt ttaatagaac aagattaata aaaattgtat acgtttagat tttatataag
    26161 aaaaaataaa aaggtaatca tgttgatttt ttatcaatat gattaccttt ttcttgttta
    26221 aataatatat tagatattag gtatttatta tataaaaatt ttaaaactaa tctgttacaa
    26281 catcaataaa gtgcataaat acctatttca agcataaaat taattaaggg ggtaatgctt
    26341 atgttagaaa tatccactga tttacaagta aatcaaccag ttattactgt tacaagtaat
    26401 acgtttatta gtatagaaaa ttatctatca atattagaat atgaagttga tttaataaga
    26461 ataaagacta aagttaaaac aattaaaata tctggggata aactttcact taagtatatt
    26521 actgatagtg agataggtat aaaagggatt atctacaatg ttgagtatgt tgattaggag
    26581 gagatacact tgataagttt tataagggga tactatgtta tagttgtgga aggagtagga
    26641 ctcgaacaat ttttaaatca tcttataaga aatgggataa gtgtttacaa tgtaactaga
    26701 ataaaaaata ctaaaatgga gtttcatata gatagacaag atataaaaga ctttaagaat
    26761 gtttatagag gaagtaagtt tgatataaag gtaaagcaaa aaactggggt cccttttatt
    26821 atcaaaagag tttataagca caaaggtatg tggatttgtg ctcttgtttc tttattttta
    26881 ttgatgtcta catcacagtt tgtgacagat gtatatatac aatctcctga aggtataaaa
    26941 aaagaagctc ttagaaatga gctttataag gttggagtaa ggccaggagt ctataagaag
    27001 agtattgata gaaaagaagt tagagaccat atgatgtcaa aatttaatga tgtggcatat
    27061 ttatctatca atgtaaaagg aacaaatata tttgttactg ttacaaaaaa ggcagaatcc
    27121 ctaaaatcta cagaccaatc aaattattgt aatgtaattg ctttaaaaaa tggtataata
    27181 gaaaaggtaa tccctagaag tggtaaatca gttattaaat ctggagacat agtccaaaag
    27241 ggagatgtct tattaaatgg agctaatacc aagtcaatac cagaagtatg ggcaagtact
    27301 ttttatgagt ccacaaaaaa ggcaagttat gtagatactg taaataaaaa aactggagaa
    27361 aagaaaaata tatatacact aagtttttat gataaagagt ttacaatgag aaaaaatata
    27421 aaatataaag attatgttgt tgaaaataaa gaaaaaaaac tatcaatagg aaactatact
    27481 tttccaataa agataaaaac gagtactttt tatgaaacaa aaaaggttga agtaaaaagg
    27541 aataaagaag agttaaaaaa agaattatct gaaaaagctt taaaagagtt agaatacata
    27601 atcccagctt cggctagaat aatagatgta aaacataact ttaaggttaa taaaaatatg
    27661 ttagaatatt taataacagt tcaaactagt gaaaatattg ctaaaattta tcctcttagt
    27721 aagtcagaag cagaaaggtt tataaaggaa gaaagtaaac cagatgaagg tgaagaggaa
    27781 gttccttcca atccagaaaa aagaccatta aatgatataa gaaatgagtt tgatgaggat
    27841 aataaggata ataaagacca aaacaattct gatgaaaata atagtaatca aaatagtaat
    27901 aatagtcaaa ataataatag caataacaac taataaaatt aaacttaaaa tcttaggagg
    27961 actaattcaa ttgataatac aaaagaaatt tacaatagca gatggtaact ttgaaagaga
    28021 gttatttggc aactttgatg aaaatgtaaa attaatagag aagactttaa atatagatgt
    28081 aatacttaga gaaggcaata taattttaat tggagaagaa aaaaatgtag attctgcatt
    28141 aaaacttatg aatgaattac accaaactgt atcaaatggt aagcatttag ataagcagag
    28201 tatttcttat tcattatctc ttttgcttga aggaagtgaa caaaaaataa aagaacttga
    28261 ggggacaatc gtcataactc aaaggggaaa agctgttcaa cctaaaactt taggtcaaaa
    28321 agaatatata aaacttatag aaaataatga tataactttt ggtgttggac ctgctggaac
    28381 aggaaagact tatcttgcgg ttgctatggc agtaaaagct tttaaaagag atgaagttag
    28441 tagaattata cttacaagac cagctgtgga agcaggagag agtctaggtt ttttaccagg
    28501 agatttaaag gacaaagttg acccatattt aagaccacta tatgatgcct tatttgaaat
    28561 gttgggtgct gataaattta ataagtattt agaaagaggt actattgagg ttgcaccact
    28621 tgcatttatg agaggtagaa cacttgataa ttcatttata atattggatg aagctcaaaa
    28681 tactacttct gaacaaatga aaatgttttt aactagactt ggatttggct ctaaagctgt
    28741 agttacagga gatgtaactc aaacagattt accacaaaat aagaagagtg gtctaataca
    28801 agctacagag attcttaaag gtgttccagg tattgggtct ataatgctaa cagatagaga
    28861 tgttgtaaga catgagttgg tacagagaat aataagagct tatgagaagc acgacaaaag
    28921 agaagaattt aaaaaagaag aacgtaaaaa agcgaaaatg caggaaaaga ctttcaaaag
    28981 aaagtaaaag tgtagtaata tagatatata gcattattaa tgaataaaaa gtaggtgtag
    29041 tgaatggatt tgatactaga tgatagacaa gataaattag aagtaagtga ggagttaatt
    29101 gaaaagataa aggatataat catagaatgt ttagattatg aaggatatga tgataattat
    29161 gaagtgagtc tttcttttgt agataataaa gagattcatg aattaaatag agaatataga
    29221 ggagttgata gagtgactga tgttttatca tttcctcttt taagtgatga ttttgaagat
    29281 gttgagttag aagaagaatc cctaggtgac atagtagtat ctcttgaaag agccttagaa
    29341 cagagtatag agtataacca tagttttgaa agagaagtat gttttttaat atgtcatagt
    29401 atgtttcatc ttttaggtta tgaccacgat acagatgaaa atacaaaaga aatgagagaa
    29461 aaagaagaac acatattaaa taagttaaac ataacaaggg agtagttttt atgaaaccag
    29521 aaaaaactcg tcaaggtata attaaagcat ttaatgcagc tatagaaggg atattgtata
    29581 catttaaatt tgaaagaaat atgaaaatac attatttagg ttcagttgct gttcttataa
    29641 taagtttgtt ttttaacttt tcaaaattag aaatgataat gttacttatg tccatatgtt
    29701 tagttgtagt tgctgaaatg tttaatacag ctatagaaaa agctgttgat ttagtaactg
    29761 atgaatatca tgttcttgct aagatagcaa aagatgttgc agctggaggc gttctagtgg
    29821 cagcactaaa ttcagtagta gttggatata ttttgtttta tgataaattg acagatatat
    29881 ctggaatatt aatttataaa ataagagaat cagaattaca tataaccttg atatgtatat
    29941 tattggttct tatagctgtt gtagttgtaa aagcattgac ttctacaggt actcctctaa
    30001 aaggaggaat gccaagtggt catgctgcct tagcatttgc tatagcaact gcaattacac
    30061 ttatgactga aagagttgtt gcctctactc ttgcatatat aatggctgta ttagttgccc
    30121 aaagtagaat tgaaggaaaa atacatacat tttgggagac tattgctgga gctttgttag
    30181 gtgtgttgat agctatatta gtatttcagc ttggaatgtt ctataattaa aataaatgta
    30241 cataaaatat ttaaaataaa acaaatctgt gctaattaaa tttttatgat ataatgtaga
    30301 gtattaaata aaaataactt ttaattattg tatacaggag gagttgttgt ggataacata
    30361 gaattgttaa ggttggcaga agatgccaga caacattctt atgctcctta ctcaggtttt
    30421 agagtaggtg cagctctttt aactaagagt ggtaaagttt atactggatg taatatagaa
    30481 tgtgcatcat taggtggaac aaattgtgca gaaagaacag ctatttttaa agcaatatca
    30541 gagggtgata aggatatcta taaaatagct atagcaagtg ataactcaga aaataatgag
    30601 caaacatatc catgtggaat atgcaggcag gtaattatag agtttggttc tgatataaaa
    30661 ataataacgg gatatactaa aggagaggtg tttgagcata gtataaagga tttgttgcca
    30721 aactatttct ctggaaatga tttaaaataa atttaaaagt ataaataaat ttaagtaatt
    30781 aaaacaagaa gataaaaagt taggagacag ttaatgttca aatcaggttt tgtcagtata
    30841 gtgggtagac caaatgtagg aaaatctact ttaatgaata atgtagttgg agaaaaaata
    30901 gctataatga gtgataagcc tcaaactaca agaaatacaa tacaagcagt atatacagat
    30961 gaagaaatgc agatagtatt cttagataca ccaggtattc acaaaccaaa aaataaatta
    31021 ggtgaattta tggtaaaggc agcaacagaa gcttttaaaa atgtagattt aatattattt
    31081 gtagttgatg attctaaaaa aataggtcct ggagatagaa agataataga ggatttaaga
    31141 agtgttaaga caccaataat tttagttgta aacaaaatag accaactaga ccaaaaagat
    31201 gagctatttg atataatcaa aatgtatgat agagaaggta tttttaaaga aatagtacca
    31261 atatcagcat taaaaggaaa gaatacggat accttaataa aagttataca aaattattta
    31321 gaagaagggc caaagtattt tccagattat atgattacag accagccaga aagagtatta
    31381 atagcagaac ttataagaga aaaagttctt cactatctta atgatgaaat acctcatggt
    31441 gtagctgttg aaattgaaaa aatgaaagcg agaaatgata aggaaatagt agatgtatct
    31501 gctgtaatat actgtgaaag agattcacat aagggaataa taataggaaa aaatggtagg
    31561 aaactaaaag gaataggtaa gtcagcaaga caagatatag aattgctttt aggttcacaa
    31621 ataaatcttc aattatgggt taaagtcaag gaaaattgga gaaatttaca aaattatata
    31681 aataattttg gatataatga taaataaagg tgggttatat ggataggaaa ctggatgctt
    31741 cccaagattt attatatgaa gtaaaatcat taattgataa taataaagta ttggagttaa
    31801 gagaattaat agaggaatat catataattg atatattcga tataatggaa aatttagagg
    31861 aagacatgaa aattcaatta tttgaagtac ttcctttaga tatggcatct tctatattag
    31921 aagaaggtag tgtagagttt tttattagta ttttatctaa actggatgta gaacactcga
    31981 aaaatatact tgaacttatg tctcttggag atatggcaga caagttgagt gaacttgaag
    32041 aagaagaaag agaacacata ataaatcttt tgaatcaaga gaatgccgat tatgtaaaag
    32101 agttactatt ctatgatgaa gattctgctg gtggaacaat gaccactgga tatatttcta
    32161 taaataaaga tatgacagct cttgaggcta tagaccatat gagagaagaa gctgaagaag
    32221 ctgaaactat ttattatata tatgtggttg atgatgaaga aaaactagtt ggagtattgt
    32281 cattaagaga attaataata gctagagacg caaatatagt agaagatttg atgagtgaaa
    32341 atataatctc tgtttatgta gatgaagata gagaagaagc agtaagatta gtatctaaat
    32401 acaatttaat agcaattcca gtagtagaca gacaagaaaa attaaaagga ataataacag
    32461 tagatgatat aattgatgta atggaagaag aagcaactga agatatgtat aaatttgcag
    32521 gaagttcaga acatgaaaga gaagttgcgg aaaaagaaaa ccctacattg agagagcaaa
    32581 taatatcagc acttagagga cgattacctt ggttaattat taccttagtt ggagggttgt
    32641 tggcttcgtt aatactttct aacttagact atataatgaa tcctgtatat gctccattag
    32701 tattttttat acctgtagta attggtatgg gtggaaatat tggaactcaa tcatcatctg
    32761 ttacagtaat aacattgtct aataaggatt taaattttag caatgtggtt agagaaggta
    32821 ttgtaggtat tattacaggt cttttgtgta gtataataac aggtattgta atttactttg
    32881 ttatgagaaa gttagacatt gtattaattg tttcaatatc attatttata aatatggttt
    32941 taggtgcaac aataggtgcg tttatgcctg ttttattaaa aaaaatggat gcagacccat
    33001 ctacagtttc atcaccaatt atatctacag ctcttgatat aactggtata gcagtttact
    33061 ttataataac aacggcatta ttgtcaaaaa ttgtttaata actttatgta tgatttatcc
    33121 tcttcttact aaaaatataa gtataaatgt aagaaggggg ttttttaaaa atgaacaata
    33181 tcagttggga agtttttaaa aaaacaggta gtatagatgc atatttatat ttctgtgatt
    33241 gcaaaaacat acatgaagaa attgaagaag taagggagaa aaaagaagac gatgataatc
    33301 ctgaacaccc aggggatagt acttaaagct ataaggtata aggaaagtga tataatactt
    33361 acactattta caagaaagct tggaaaagta tctgcaatag caaaaggagc taaaaaaaat
    33421 aagagctctt tgctttcatc atcacagtta ttttcttata gcaattttac cttaaaaaaa
    33481 caaggtaata tgtacaaggt tactcaaagt gaaataataa aaagttttta taatatatcc
    33541 tatgatatag aggcattttc ttatgctaca tatattacaa aattagttga aaattctata
    33601 cttgaaaatc agactaataa taggctattt atattacttg cgcagactct gtatttgtat
    33661 acacaggata atacagacaa taggtttata acagcagcat tcgagttaaa atttttagac
    33721 tatataggat ttaaacctat agtaaataaa tgcattaatt gtgaatgtaa aattttacaa
    33781 aattctgtgt ttaatatcta cgaaggtggt atactatgta gtaagtgtag taaacttttt
    33841 gataataata taaaattaga cttaacaact ataagtctta tggaatatgt attaagaaat
    33901 gatattttaa catgtagtaa agctaaagta tcaaaatata taacacatga acttgagaat
    33961 attctagaca agtatttgaa agtttatgtt gataatatta attttaaatc attacacgta
    34021 ttgcaaagtg taaaaaataa taagggagtg gataatgatg agtagtaata taactattga
    34081 aatggttgat tcagtctttg aaagagttcc aggagcaact tatgcagaag caaaagaagc
    34141 attagtaatg tgcaatggag atgtaattga ggcagtaata tatttagaaa ataaaaaaaa
    34201 tacttgtaat tgtaaagcaa aatctgctaa agaaactatg gaagaagtat ttggcaaaga
    34261 tggagaaaat ataaagtttc aattaaaaga gcttcttaga aaaagtagtg tagtgcgaat
    34321 aatagttgaa aaagatggaa aaactatgat gaacattcct ttaacagttg gagttgttgg
    34381 attagctttt gtaccattag ctactttagt tggattatca gctgctgtta taagtaaata
    34441 tcgtataaaa gttcaaaatg aagaagatgg agaaattgta gatttaggtg aattgaatga
    34501 agaaaaactt cacgttttga agaatatgat aactaatgca gcaaaagatg tgaaggatgt
    34561 agtagttgac aaaaaagaag atgacaaaga tgtaactgct gaccttatga aagaagaatc
    34621 tgaaaagaat aaagaagacg aagacgaaaa taaatagata taaagtgact tttaaaaaat
    34681 gaagagaaga taattataag aattatcact aacattgaca aattttatag aatttgatat
    34741 tctaaaagtt gtagaagaac tattaaaata gcctttcgtg tagacgagag gctttattgt
    34801 tataggaggg atttttatga attttcaaga gatgatactg gcgttgcaaa aatactggtc
    34861 aaagcaaggt tgtatcatga tgcagcctta tgatattgaa aaaggtgcag gaactatgaa
    34921 tcctaatact tttttaagat cattaggacc tgagccttgg caagtatgct atgtagagcc
    34981 ttcaagaaga ccagcagatg gaagatatgg tgaaaaccca aacagactat atcaacatca
    35041 tcaattccaa gttatactaa aaccttctcc agataatata caagaattat atttggaaag
    35101 tttaaaagag attggaattg acccaagtga gcatgacata agatttgttg aagataactg
    35161 ggaagctgct acagttggtg cttggggact tggatgggaa gtttggctag atggtatgga
    35221 aataactcaa tttacgtatt ttcaacaagt aggtaatatt gaatgtgagc ttgagacagg
    35281 agaaattaca tatggattag aaagattagc tatgtacatt caagaagttg atagtgttta
    35341 tgatttaaaa tggaatgata aaataactta tggtgaagta tttaataaag ctgagtatga
    35401 aaactcaatg tacgcatttg aattatgtga tgcagatatg ttgtttaatc tgtttgatat
    35461 atatgaaaaa gaagcattaa gacttatgga aaatggcctt gtaatacctt catatgacta
    35521 tgtgttaaaa tgctctcatg catttaatac attggatgca agaggtgcaa taggagttag
    35581 tcaaagagct tcatttatag gtagagttag aaatatggca aagactgttg cagaaacttt
    35641 tgtaaaacaa agagaagaaa tgggattccc tcttttaaag gacggtgaca aataatgaaa
    35701 aattatcttt tatttgaaat cggtgttgaa gaaatgccat caagatttgt aggcagtaca
    35761 ctagaacaat taaaaaacaa tcttagtaaa ttatttgatg aaaatagaat agcttttgat
    35821 aaaataaatg cgtatgggac accaagaaga cttactttag tagtcgaagg attgagtgat
    35881 agacaaaatg atttagaaga ggaaataaag ggtcctgcta agaaaattgc tgttgatgca
    35941 gaaaataatt taacaaaacc agcattagga tttataaaaa gcaaaggatt aagcgaatct
    36001 gacatatatt ttaaacaagt tggaaaagaa gaatatatat ttgcgactat aaagcaagat
    36061 ggaaaagaaa cttcagaagt actaaaagac atattaccag agactataaa atctgtagta
    36121 ttcccaaaag ctatgcgttg gggaggaaaa aatcttaaat ttgcaagacc tataagatgg
    36181 atagttgcat tgttaaatga taaagtatta gagtttgatt tagaaggaat aatatcttct
    36241 aatgtaacaa aaggtcatag atttttaggt gaaagtacaa tagaagttga ttctatagaa
    36301 gattattttg aaaaattaga aaaaaattat atagttttag accaaaacaa gagaaaagaa
    36361 atgataagaa aacaatgtat agaagtggca aattctttag gtggagaagt tgaatttgat
    36421 gaagatttac ttgaagaggt aacttactta gttgaatatc caactgcttt ttatggagaa
    36481 tttgatgtgg attatataaa actaccaaaa gaagttgtta taactcctat gaaacaacat
    36541 caaagatatt ttccagtact taaagaagga aaactgttac ctaactttat agctgttaga
    36601 aatggtgatt cttacagaat agacaatgtt aaagctggaa atgaaaaagt tttagaagca
    36661 agacttgcag atgctttatt tttctataga gaagatacta agagaaactt agaaagctac
    36721 atagaaaaat taaaaactgt tgtattccaa gtaaaactag gaactattta cgacaaaact
    36781 ttaagacttg aaaaattaag tgctgatata cttgatagtt taggtttagt agatgaaaag
    36841 gcagatacta taagggctgc taaattatct aaggcagatt tagttactgg aatggtagga
    36901 gaatttgatg aattacaagg ttttatggga aaagaatacg caaaagttgg aggagaaaat
    36961 gatgttgtaa gtgaagctat ttttgaacat tatcttccaa gatttgcagg agatatactt
    37021 cctaagacta atgcaggagt tgccttatca atagctgata agttggattc aatagcaggt
    37081 ttctttgcta taggaataca accaacaggt tctcaagacc catatgcttt aagaagacaa
    37141 gctttaggta tacttagtat acttatggac agaaaagttg ctgtggatat aaaagtactt
    37201 attgaacatg ctttagacaa ttattctgaa ttagatttta ataaagaaga agttgttgag
    37261 caaataatga atttcttcaa tgagagagta aaaaatctat ttaaagattt aggaataaga
    37321 tatgatgttg ttgatgctgt tttaagttct gatataaatg atgtttctga tatgcatatg
    37381 agagctttag agcttaataa ttggctagaa aaagatgaat tagtggagat gcttactgca
    37441 tttaatagag tttctactct agctcaaaaa gcagaaagtg ataaaattga tgaatcttta
    37501 ttaaaagaag atgctgaaat taaactttac aatgaattta aacaagtaaa ggtaaaagtt
    37561 aatgaattat taaaggataa gaaatatggt attgctttag atgaatttgc atctttaaga
    37621 ccagtagttg ataatttatt tgatacagtt atggttatgg ataatgatga agctattaag
    37681 aacaatagac ttgctttact taaacaagta tatgatacta tgctaggaat ttgtgattta
    37741 tctaaaattg tttataaata aaatttaaac tatttataag aaataaggct gtctcaaaat
    37801 agagatagtc ttatttttca ttgttgagat gatgaaaata tatttgattt catagaaaaa
    37861 gagtgtctca taaactaaaa agttcatttt gagacaccca tgctttttgt aagtaaatat
    37921 aataaattat attttatact tatcagttat tttgtttaaa atattatcat ttgaatttac
    37981 ccattcataa aaattgcctg atgatgcgtc cgatatttta taaagcattt caggaatatc
    38041 actagcttta aaatctccaa gtgattttcc caatctagtc ttacctattt caaaactgcc
    38101 tccaacaaat aattcaaatg catctgtaga tataccatca acattcttct ttttaccaca
    38161 taaacctatg ctaccaactt gatgaacacc acatgaattt aaacatcctg atatatataa
    38221 cttaggtgct ttatttaaaa tttctttatt attttgtaat ctaaaataat ctatgatttc
    38281 atgtaacatt ttctgactat tttgtatgcc catttgacaa attggaacac ctatgcaaga
    38341 tatactttgt tctaattgag aattacaact aatagtttta cttatttcta atattctttt
    38401 tgcttcattt ccatttaaat ttaaaatata taatccctct gtcattccta gtctaatcat
    38461 aggattttca atattatcta attctttaag taaagtactt aaatcctttg ttaacaaaat
    38521 acctccaact ggatgtatat atacagtgta taaaccatcc tgtttttgag gtattagtct
    38581 agaatcctgt atatctattt taaccccagg tttagagtaa tctatttctt caatattgag
    38641 ttcaagacta ccattttctt tttctaattt atagtattct ttaaattttt ctaagaataa
    38701 tttttcacca agtgattcga ccatatatct aaccctagct ctgtttttat tttcataatt
    38761 tccataatcc ataaagaatt taatcatacc ttcaacacaa tataaggcat ctttcggttt
    38821 tataagttca tcaagttcta aagcaacttt gggttgttta cctagacctc cacctaagaa
    38881 aactctgaaa tatggttcat catttttcaa agtagcaaca aatcctaagt cttgtatact
    38941 acaatgagca gtatctgtgt aacaattaga ataagaaact tttaattttc taggtaaatg
    39001 gtatgtagta gcatttttga taaaatattt atcagtagca actgcatatg gagtaacatc
    39061 aaagacttca ctagggtcaa ctccagataa tggagataat ccgacatttc taggataatt
    39121 accaccacca cctctagtga atatatcatt ttttattcct tcttccatga tatcaacaat
    39181 tgaatttata gataaatcgt gtaattgtat agcttgtcta gttgttaagt gtatcttatc
    39241 taagttgtgt ttaatagcta tttcatagat tttattaagt tgatactgag ataaaactcc
    39301 agcagatact ctaagtctta tcataaaaga ttttttgtct ctttgagcat aaacaccata
    39361 tccaccagaa aatcccttat attgcatttt atttatttct ccatttaaaa attttgaaga
    39421 atattcttta aaattaggta gttcatttaa caatatcttt ttaaaattat ccattatttc
    39481 acctcattgt tagtcttgta taaaaatata tc
//
LOCUS       DAMJWC010000036        38592 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMJWC010000036 DAMJWC010000000
VERSION     DAMJWC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38592
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.036"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(263..1603)
                     /locus_tag="PC503_002098"
     CDS             complement(263..1603)
                     /locus_tag="PC503_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2528070.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
     gene            complement(2273..3364)
                     /locus_tag="PC503_002099"
     CDS             complement(2273..3364)
                     /locus_tag="PC503_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2528071.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(4132..6051)
                     /gene="thrS"
                     /locus_tag="PC503_002100"
     CDS             complement(4132..6051)
                     /gene="thrS"
                     /locus_tag="PC503_002100"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF2528072.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(6115..6353)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6965..7567)
                     /locus_tag="PC503_002101"
     CDS             complement(6965..7567)
                     /locus_tag="PC503_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF2528073.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     gene            complement(7747..8565)
                     /locus_tag="PC503_002102"
     CDS             complement(7747..8565)
                     /locus_tag="PC503_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF2528074.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(8568..9329)
                     /locus_tag="PC503_002103"
     CDS             complement(8568..9329)
                     /locus_tag="PC503_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528075.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(9819..10931)
                     /locus_tag="PC503_002104"
     CDS             complement(9819..10931)
                     /locus_tag="PC503_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2528076.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDFIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(11057..12061)
                     /locus_tag="PC503_002105"
     CDS             complement(11057..12061)
                     /locus_tag="PC503_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2528077.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(12349..13197)
                     /locus_tag="PC503_002106"
     CDS             complement(12349..13197)
                     /locus_tag="PC503_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2528078.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(13233..13703)
                     /gene="trmL"
                     /locus_tag="PC503_002107"
     CDS             complement(13233..13703)
                     /gene="trmL"
                     /locus_tag="PC503_002107"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF2528079.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(13897..15066)
                     /gene="nth"
                     /locus_tag="PC503_002108"
     CDS             complement(13897..15066)
                     /gene="nth"
                     /locus_tag="PC503_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF2528080.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKEEINKKGMNKKDIIEKEEINKKGMNKKDIIEKEEINE
                     KGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKGETEKKTKKSSSNKATQ
                     KTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILSAQC
                     TDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLCELY
                     DGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPNPQK
                     TEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK"
     gene            complement(15264..17501)
                     /locus_tag="PC503_002109"
     CDS             complement(15264..17501)
                     /locus_tag="PC503_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528081.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(17607..18521)
                     /gene="queG"
                     /locus_tag="PC503_002110"
     CDS             complement(17607..18521)
                     /gene="queG"
                     /locus_tag="PC503_002110"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF2528082.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     KYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            19543..19947
                     /locus_tag="PC503_002111"
     CDS             19543..19947
                     /locus_tag="PC503_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2528083.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(20204..21199)
                     /locus_tag="PC503_002112"
     CDS             complement(20204..21199)
                     /locus_tag="PC503_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2528084.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(21483..22319)
                     /locus_tag="PC503_002113"
     CDS             complement(21483..22319)
                     /locus_tag="PC503_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF2528085.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(22807..23370)
                     /locus_tag="PC503_002114"
     CDS             complement(22807..23370)
                     /locus_tag="PC503_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528086.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(23468..24397)
                     /gene="glsA"
                     /locus_tag="PC503_002115"
     CDS             complement(23468..24397)
                     /gene="glsA"
                     /locus_tag="PC503_002115"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF2528087.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(25356..27023)
                     /locus_tag="PC503_002116"
     CDS             complement(25356..27023)
                     /locus_tag="PC503_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF2528088.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(27097..27852)
                     /locus_tag="PC503_002117"
     CDS             complement(27097..27852)
                     /locus_tag="PC503_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF2528089.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EILTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(27862..28398)
                     /gene="lepB"
                     /locus_tag="PC503_002118"
     CDS             complement(27862..28398)
                     /gene="lepB"
                     /locus_tag="PC503_002118"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2528090.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(28564..29100)
                     /gene="lepB"
                     /locus_tag="PC503_002119"
     CDS             complement(28564..29100)
                     /gene="lepB"
                     /locus_tag="PC503_002119"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2528091.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(29200..30510)
                     /locus_tag="PC503_002120"
     CDS             complement(29200..30510)
                     /locus_tag="PC503_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF2528092.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(30589..31305)
                     /locus_tag="PC503_002121"
     CDS             complement(30589..31305)
                     /locus_tag="PC503_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF2528093.1"
                     /translation="MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            31550..32821
                     /gene="sleC"
                     /locus_tag="PC503_002122"
     CDS             31550..32821
                     /gene="sleC"
                     /locus_tag="PC503_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF2528094.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(33247..33903)
                     /locus_tag="PC503_002123"
     CDS             complement(33247..33903)
                     /locus_tag="PC503_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528095.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(35015..35425)
                     /locus_tag="PC503_002124"
     CDS             complement(35015..35425)
                     /locus_tag="PC503_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528096.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(35641..37023)
                     /locus_tag="PC503_002125"
     CDS             complement(35641..37023)
                     /locus_tag="PC503_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2528097.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(37034..37393)
                     /locus_tag="PC503_002126"
     CDS             complement(37034..37393)
                     /locus_tag="PC503_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2528098.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(37598..38377)
                     /locus_tag="PC503_002127"
     CDS             complement(37598..38377)
                     /locus_tag="PC503_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF2528099.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT        12696 a         6960 c         3569 g        15367 t
ORIGIN      
        1 ttaaattctt atatattaaa tttctatgca tcacttttat acatattaaa ttcctatata
       61 ttaaactttt atgcatcact tttatacata ttaaattctt atatattaaa cttttatgca
      121 tcacttttat acattagttc ttatatatta aacttctatg catcactttt atacattaat
      181 tcttatatat taaacttcta tgcatcactt ttatacatta attcttatat attaaatttc
      241 tacacatcaa atttatatac atttaaatca catgattaac tgctttcttc acatttctaa
      301 gtggaatagc aattttaact acaaattttt tatcatcata ttcaattaca acattaccac
      361 catacttatt tacagagttt tttacacttt ttattccaag tccatgaaga gaaccttttt
      421 tgtctgtcaa aatatctcca tttttagtaa taatcttatt tatcttagta ttttcaactc
      481 ttattaaata aaaattttgc ataacatcac ctttaacaca aataactcta tttccactat
      541 caattttatt acatgcctca attgcattgt ctaaaatatt tgaaaatata tgacatatat
      601 ccactaattc aacagcttca caacaactaa aatttattcc tatttttagt tctatatcat
      661 tcttatcaca aacctctttc ttttcactta atatagcatc taatataaaa ttaccagtat
      721 taaataacaa gtcattactc tgaatttcta cctgcaaatt atttaaataa gaagtaacat
      781 caataccttt tttaatcata gcatttatac acaatatgtg atttttcata tcatgactta
      841 gtaatctagt ttttaaatat ttcttttcta tatcttcata atactcattt tcatacttca
      901 aagtattttt aatcatattg ttttctacaa ctaaagtatt atattgctgt aattttttag
      961 caattaaaac taaagtgata cttgatataa gcaatacaac agaaatcata acgaattgga
     1021 aattatgtat taagctacca gaccctggat taaatatgta ttcaaaaatt acaaaaaaag
     1081 atgctatatt agcgactata ggaataacta tataaaataa tgtcctttta tttatttcta
     1141 tattaagttt tatctttaag gctctatata aaagcaaaga cacaatcaaa agtatctttc
     1201 ccaatattat agactcaatt ctgtatatat ctcccgtccc catactactc atgtcattta
     1261 tagaattaag ccaaactgtt aaagatatac tcaaagcatc tgtggcgatt agtaacatcc
     1321 aataaattaa ggatattaat acagacttta taaaccccac atcatatgag attttataaa
     1381 atgcaatagt aattatcata gatataatta ctcttatatt tggaggtaca tcaaaaaaat
     1441 atattatgtc agcaaaaaca ataataccta ccatacaaaa gtttattttt ttgttagaaa
     1501 tccttttctc acttgtataa tctagcattt tcttacaaag aaaccattct atcataaagg
     1561 atatcgcaat gaaaatattc caaaataagc ttgactttat cataatactt tctcctaacg
     1621 tattactaaa ttattttttt atattttatg tataatttaa ttatatacga ctctacacat
     1681 gtagtaaata gattgtcaaa attattccaa ataagtccat atttcttttc ttttttaatt
     1741 atatcactaa atttgctaaa ttgaattaaa ctttttattg ctttttttaa taataactat
     1801 ataaatttat ctataactag gtataaaata tattatttat aaagttttta cattatttct
     1861 ataataaaat cttataaata ttacaataaa atattttttt ccatgatata ccttgataaa
     1921 atctctgctt ctttaagcag taactttgag ttgaatcatt atagtgattt ataacattta
     1981 tagaaatgct gttatagatt tatatttaaa cactacaaat ggaaatttaa ctattataaa
     2041 aaacaatcat tagataaaat gattcttaca acaaaagcat ttctattgta gatttattag
     2101 taaataataa atctacaata gaaaaaacta gaagtacagt atcataaaaa tataattaac
     2161 tgtacttcta aattattgtt tttaaaataa attttcattc attaaaaaat acatataaat
     2221 atttccagac tccgattcag caaacttata taagttcact ttttatttat catcaattat
     2281 tttcatatac ttcttttatc tcatcttcac ttaagtcaaa atcattaaat ttatttaata
     2341 tgtcatctaa tttaaaacca ttttttttca acattataat tattttataa tctttttctt
     2401 ttgcaactct aattgctgtc tctctttcaa tctcttcttt aaaatttcta cttttattca
     2461 tgatataagc acctcttttc agatttaata aatattcttc attgctacct aattctttta
     2521 atctatcaag tgctttttta ataatagaat cattcttagc tataactctt acatctaagt
     2581 tagaaggatt actaataagt tttccccata gcataattct atttactata tagtcagatt
     2641 tatgaatttt tggaagctct ataaaatata atgcagtttt actagaataa atatctggat
     2701 gcccgtccat tgttaatctc aggcaattta cataatcttc tatgtgatta tattttacat
     2761 gatttagtat atgtattcca atagtttttc caatttcttt atactcttta ccttcttcta
     2821 actttctacc atgtacacga ctaagataat attcagctct ttccaaataa tcgttctcaa
     2881 aagctctttg catctcaata tttatatgat tattttcttc atcttcagcc aaaatatcaa
     2941 gtttaggtct tttctctcca atgtaattaa ttgttggatc agtttcaact ctaattattc
     3001 tctttatttg agtgaacggt ttgatattcc tgttagcata tggagcatct tttagaatat
     3061 catttataaa atttacaagt aaatcatatt cattatttaa agtgaacaat gatttaaata
     3121 cctcatcata ctcaggctta gcatatccat cttcagtcac aacttctcca acattttcat
     3181 tagtcaaaat ctcttttgga attaatgcct tgattttatc taattcatca ttagaaaaac
     3241 tacttctact aagtatatca tttaattttt tggtccattc tttatctttt tcttcaatta
     3301 tagttcgctt atattctttt gatgttttaa taatcttaga tttttcttct actttttcta
     3361 tcatttcaac acctctcttt ttcctctttt gtatttatca tttcttgaaa ttaaactaag
     3421 tcactacctc ttttaaaagt tcttgctcca taaacacttt cttaaactct aatgtctgtg
     3481 tatgtacttg acattctctc tctatctaaa gttaaataaa ttaatctatg tatagaggat
     3541 aagtccaaaa ataacataaa acactaatta atcatttata aagcattaat taatcactga
     3601 caatgctgtt attgtcacca catagcacca acatagattc ttctattata gggcaattat
     3661 ctatgaaaaa tagactcata agattagaaa atgtacttaa attttagttc atttaaatat
     3721 tcattttgaa gaaagaaatt taactttaga ctaaaaagga aatatttcaa gaggattaag
     3781 aaattttctt aaagggataa taatttttat gaaaatggaa caaatatgaa aataaagtta
     3841 tgatttttac agccataacc ttaccaacaa gcacttaatt atcactcaaa aaataaactt
     3901 ttatttaaag aatgcacata aatatttcca tgttcaaaac acttctatga tatatttatt
     3961 aataaatcta ccatacaaaa aactagaggt acattaatca taaaaatatg attaactgta
     4021 cctctaatta tactcatctt ttcataaatt taatcactat gcatcaacat atcaacatat
     4081 tgattaaact tatcttatat aacaatatct tagctactaa tataatatat attagtcttg
     4141 aataatactt tctcttgatt caatttcttt tgaaatacta gctataaatt catctaattt
     4201 aatactacct atttcacctt tatctcttga tctaacagaa acattattat cagctacttc
     4261 tttttcacct actattaaca tgtatggcac tttttcaagc tgagcttctc ttatcttaaa
     4321 tccaattttt tcagctctat catctaattc aactcttata cccttatcaa ataactcttt
     4381 cttaacttca tttgcataat ccataaattt atcagatata ggaagtatct taacttgagt
     4441 tggagataac caaactggga atttaccagc ataatgctct attaatatac ctataaatct
     4501 ttctatacta ccaaaagcaa ccctatgaat cataactggt ctatgctttt caccatcttg
     4561 accaatataa gtattatcaa attgtcttgg aagctgcata tctaattgga tagtaccaca
     4621 ttgccaagtt cttcctaaac aatcttttag atggaagtct atcttaggac catagaatgc
     4681 tccatcaccc tcattaatag tatatggtag acctaactct tctaaagctt ctcttaatcc
     4741 attttctgct gcttcccact cttcgtcgct tcccatagag ttctctggtc ttgtagataa
     4801 ttctaaatta tattcaaatc caaaagtttt gtatatacca tctattaagt tagctactcc
     4861 ttttatttcg tccttaattt gctctggtaa catgaatata tgtgaatcgt cttgagtaaa
     4921 tgctctaact ctcattaatc cttgtaatgc accagataac tcatgtctat gaactctacc
     4981 aagctctgca actctcattg ggaaatctct atatgaatgt agttgagagt tatagtaaat
     5041 taatccacca ggacagttca taggttttat agcataatcc tcatcatcta ttttaactgt
     5101 atacatattt tctttgtaat gataccagtg tcctgaagtc tcccataatt ttctatttaa
     5161 tatgattgga gattctatct caatatatcc agcttttctg tgtatttctc tccagaattt
     5221 taataattca tttttaagtt ccataccttt tggtaaaaac atagggaatc ctggaccttc
     5281 ttcaggtatc ataaataatc ctaattcttt acctaatttt ctgtggtctc tctttttagc
     5341 ttcttctagt aaatgtaagt actcttctaa gtctttgttt ttctcaaaag aagttccata
     5401 tattctttga agcatcttat tattttcgtc accacgccaa tatgcacctg ctacactttg
     5461 taatttaaca gcttttacct ttttagtaga tggtaaatgt ggtcctctac ataaatcagt
     5521 aaaatcacct tgcttgtaga aagatattat ttcactttca ggtaaatcag aaataagttc
     5581 taccttatag tcttctcctt gttctttcat aagctctaaa gcttcatttc taggaagttc
     5641 aaatctttct atttttaaat cttctttagc tatttttttc atttcagctt ctattttctc
     5701 taggtcctct ggaactaatc tatggtctaa atctatatca tagtagaatc cattttctat
     5761 acttggtcct atagcaagct ttgcttctgg gtaaagtctt tttatagctt gagctaatat
     5821 atgcgctgat gtatgtctaa aaacttcctt accttcttta tcttcaaact taaataaatt
     5881 caagtcacaa tcagtatcta taatgtggtc cagacctaca acctctccgt tcacagacgc
     5941 tgctaccaca tttctagcta atccttcact aatggattta gctacatcca taacagaaat
     6001 agcattttca aattctttta ttgagccatc ttttaaagca actttaatca ttgttttttc
     6061 ctccttattg aaataatttt tagatttttt gtaataaaaa atcgccccaa atatgtttgg
     6121 gacgatatta attcgcggtt ccacccaagt tggcgtatac aagtatatac aaccctcttg
     6181 atgactataa ggtcgtcacc cgagcacttt cacgtatagt ataaatacaa atactgctaa
     6241 taagctcagc tccaaggtag ttttcaaata gacctattac atgggctctc agccatagac
     6301 ccaaattctc tgagaatggt ttctactcta ctcttcctct tcaacactat gatttttaat
     6361 atattttcat tataacagat agttatacat caatcaacat taatgtaata tattaattac
     6421 ccattatttt tcatctcaat cagctgtaaa ccaatattct tatattttta tattaaatta
     6481 atctcttgat ttatagttat attataatat tttcataaat ttaaaatttt taaaacgtat
     6541 ccacatgcat gatagatatg actagataaa tactaaaact aatttttatt aaaactaact
     6601 tctaattttt gtactctttt taggttttgt atacttaaat acaatcaata cttaatatgg
     6661 ttaataagta gtacagtaaa tacttaaata ctattaataa gtaacacaat caaataaata
     6721 aatacaatta atatctaaat gctattaata agtaattcac tcaaataggt aaatacaatt
     6781 aatatctaaa tactattaat aagtaattca ctcaaatagg taaatacaat taatatctaa
     6841 atgctattaa taagtaattt actcaaatag gtaaatacaa ttaatatcta aatgttatta
     6901 ataagtaatt cactcaaata ggtaaatata attagtactt aaataaatgc tacttctcat
     6961 atatttaaat aaacatagta attaaccctt gagctatacc tattaaaaac cctaagacaa
     7021 gccccaaaaa ctctatatgt tttaattctt tcttagctat tcttattatt atctcttcca
     7081 attcatataa atctagttca ttaatcttat cttcgaccat tttttgtata tctatacgtt
     7141 catttgcttt atttattata tttttactca attcatctat actttgctta acttcagact
     7201 caattatctc tcctagataa tcttgtatca tgttttttat accactcggg ataaatgaaa
     7261 ctttctcatg tattataatt tttacccttg cttttatgta tcttacaact tcttccttat
     7321 cttcgtcagt aatgatattt gcaagtattt cgtccataga aagaaattct tcttgaatta
     7381 tttctcctac atttgctgct atttctgctc ttctctttgg tataagacct actatttcta
     7441 tatttaaaat aggtatttta ataggctcta ttggtctaaa tatcagtctt atagcaacta
     7501 cattcgtaac ataacctata aatccaccaa taacagctaa tatcagtatc ctaattaaat
     7561 tatccattat aaaattactc cttatcaatt gtatatttgc cagctatatt gcattaatca
     7621 agtagatatt ctttatactt aataactcta gttatactat agctttatat acaattataa
     7681 gtcttttgtg tcgatttaaa aagaattttt ttaattttat atggatagct tttatatgct
     7741 tagattctag ttttccataa ttatactaac tttattttca aaaattgctt ctacagtatc
     7801 tataatttcc tttgagcaat tattatttaa caaatccaat atttctattt ttttgggaca
     7861 tagagttaat aaggtactta ttaaaaagtc ctcataattt aaattttctc ttattaccat
     7921 atttataatt tcttcatcat ctatactgtc tatcttattt ccatttttat cgtataaaac
     7981 aaatgtatta tcttccatta tatgaacttt aagcaaatca atcttttctt cttgagtatc
     8041 tataaagtat tttaaaactc ttataaattc atcttggtct ttctttatta aatactcctc
     8101 aactgcaata tcacctatag cagaaatata tttcataaat tctctcattc taaatctaat
     8161 aaaaccttct acatttataa aatcattttc ttctatataa tttctcaccc tagtaaatac
     8221 tgtttctctc ataaaaatct cttttttagc aaatatgttc agtgaatata tgtatatatt
     8281 atttttatct tcaggatatg tacgcccata gcattttaga atgtattctt tcaaaagttt
     8341 ctctttcatt atacttatta tcatactagt tatttccgtt gatatctcat caatatttaa
     8401 agctctttgt tcagctttag taccattaag tattttttta tttaacactt cttgctttgc
     8461 agaatctatc actacttcta caatgtcatt cgtatatatt aatctatcgt ttacattatt
     8521 attcctcaaa aatttcatgg aagaaatatt atccttctca accaaagtta tcgctccttt
     8581 cttgtcatga gaggaactat agaacctata tctagtaaat tttcacagct aagtgtaact
     8641 atctccttgt ttttactttc tacaaaactt tttatacgtt catagtcagg atgtttttta
     8701 acatctccac aaaaagctag tttatcctta gaaatcaacc ctgtacatcc acctataaat
     8761 ccataattca tctcaaataa atttatgtga cctttttcta tcaataaaca ctctatttct
     8821 gtattcttca tacttttcca aataccttta tctgatgtta ttatagacgt tctatctact
     8881 atacagattg agcatttaga atagccctgc tctatattta tctttttaag tttattattt
     8941 tcaatataat ctaatattgc tttgtcagta tacttaaaat tgtgtatagc atagtcacca
     9001 actatcgcaa tattgtaagg tatatcataa gggtatctat ttaataaatt agcttctccc
     9061 ttaattatat taaatttata tctacttaat aactctttgt attgattata tacattcggc
     9121 gcaacaatta tatctccttt tcctaaatta caaatacata tatccgggtg atattttatg
     9181 ctttcatata attctttaca ttctattgtt tttattatct ctatatttct taattttaat
     9241 tcattttcca ttagataact aattcttttg tccaccaaag ctagacacaa atcgtcatct
     9301 agtataaatg gttctcttgt aaattccatt ttttactcct ttttcttttt tttgataaat
     9361 tttttatgtg aatataaata aagtgtgtag cagaattttt ctgcccacac acttattgtt
     9421 ataattttat atagttattc taagcttaat tagtatagct ttgtacagtt ggttcaaatt
     9481 taataaatat atctttttat cactaatcta aacttaagca gtatattccg tacagttagc
     9541 acaaatttaa taaatatatc tttttattgc taatctaaac tcaatcaata tattttgtac
     9601 agttagacta aatttaataa atatatcctt ttatcaccaa tctaaactta agcagtatat
     9661 tccatactgt taacacaaat ttaataaata tatcttttta tcactaatct aaacttaatc
     9721 aatatatttt gtacagttag cacaaattta ataaatatat ctttttattg ctaatctaaa
     9781 cttaagcaat atatttttat aatcttctac atcaataatt aatatgtatc tttcactttg
     9841 ttatactctt tttttatgta ttccaaaaca tctggtggta tatttctact gctctttgaa
     9901 gtcaagccaa gttccccatc ttttatttta aattccatta ctttacttcc cttaaaacca
     9961 tcttttgcaa cgttctttat cagttcatat acaggttgtt ctacatcttt tataattgaa
    10021 cttattacat tatctggagc catatcgtat tggtctttat taatagctat aactttacca
    10081 ccattttctc ttgctacctg aatagctctt ttactatcat cttctgtagc tgaaaataca
    10141 acatctctat cagaatctct catttccttt gcaatagttc tagctgattc agggttttca
    10201 aatatatttg aatacttaac tagtaactca gcatctttat ttgaagtttt aagccccttt
    10261 ctaaatccag attcatactt atctctacta gaaccctcaa ctcctcctat aaaaccgact
    10321 ttcccagtat cagtcatttt acctgcaata agtcctgcta aatatccagt aacattatct
    10381 tgaaatgata cagaaattac attagctggc tgaactttat aagtatagtc aactattgca
    10441 aattgctgtt tgggatattt agtagcagct tctttaattg gctctgcaaa tctggctcca
    10501 actgctatta taaaatctgg ttcatactta tgcagttttt ctatactctc tttaaaactt
    10561 ttagaagtct ttggtttttc aagttttatc ctaacatcaa aatcttcgtc agcccttttt
    10621 aaggctgata gtacattgtt attatatgat tcgttattta agttttcggt atctaacaat
    10681 actccaatag tttttcttac atatgaatca tcttctgtgt catcttcttt attcttactt
    10741 ttactatttg atttatcctt ttctgctgaa gttagcaaac ttttagactc actctgtttc
    10801 gatttagcac tatctatatt agaattattc ttatttactt tatcaaaccc aaaatcaaaa
    10861 ttacatatag ctaatataaa aattgtaaaa actactacaa agcaagccat caatatcctt
    10921 tttattttca caaaattcac tccctgattt agataggtct gacctacctc tgcatatgtc
    10981 tttctatata tgtctattat aacatccaat tcacctcata actaaactca taagtattct
    11041 tggatattat agtagattat ttattgttct tattaacata ttctaacaca tctggaggaa
    11101 tattttgaga actattttgg gcaagtccag tacttccaga cttaactgtg ttttctataa
    11161 cctttccgcc tttataattt ccttttacaa aactttgtat cagattataa gtaggattct
    11221 caaaatcttt tacaatagaa cttataacat tttctggagc taactcatgt tggtctttat
    11281 tcgttgctat aactttttta ttttttgccc ttactgcatc tattacagct tttgaatcat
    11341 cttcagtagt agaaaaaata atatccactc cattatccat cattttttta gctatagatt
    11401 ctactgattt gctatcttta aaaacatctg catactcaac tgaaatatcc tttatactac
    11461 tattagaaaa tttaacaccc tctctaaaac ctgattcaaa tttatctcta ctagaactct
    11521 ttgttcctcc tataaaacca accttatcgc tttcagtcat ttttccagca attaatccag
    11581 ctaggtatcc agatttatta tcttcataag aaattgaagt tatattagaa ggttgcttgt
    11641 catactcata gtctataatt gcaaattgtt gctttggata tttcttggct accatctcca
    11701 atggttttgc aaatctagct cctacagcta taattaaatc gtaattgtca ttacataaaa
    11761 tatctatact attagaaaaa gttgaggaat catctgattc cactttgttt gtatctatat
    11821 taagtttctt ttgagcattg tttaatgcta ataaagctga attattcata gcttcattat
    11881 ttgttccttc aatatctagt atcattgata cagatttttt tgaattactt ttatcgctta
    11941 tatcactttt attatctttg ctagagctag gattattact tgggttatta gcacacccaa
    12001 ccaacattcc agctatcatt gctacagtta acatcaatat caatattctt ttgaaacgca
    12061 ttaaatttca ctcctcatac atttacgata tttttatatc ctatttactt ttacatccta
    12121 tttataattt ttttatatac aatttacaag tacattttga aattttttta ataaatctta
    12181 ctataaaaaa gtgtgcaata gattcttatc tatttacaca cttccctaca aactaaatct
    12241 aatatatcaa cacttaattt catccaaaat aaatccaatt taacatctca acaattaata
    12301 ttctatccta atttaataaa aaaataaata atgtcatcca aaaatatatt atttattttt
    12361 taagcatatg ataccagtaa caccaggacc agcatgtgca cctatacaca caccaatttg
    12421 gaaaaatcta atttctttag gtcttaattc atcttgcata accttagata attgttcttt
    12481 ttccttaaaa tcatcactat atcctatata cacaatttgg tctgataaat catcaccaca
    12541 atttgatttt atcaattcca tcatcttaga aattacattc ttctttcctc ttacttgaga
    12601 tatttgcgaa actaatccat ctcttatttc aagaatcggt tttatattta atatacttcc
    12661 tattgctgcc ttagtagatg atattctacc tcccttttgt aaatattcca atgtatctac
    12721 tgaaaatata acaaaagcct tctcttttaa ttcatccaaa acaggcaata tttcagcaac
    12781 agactttcct tcacttgcaa gttctcctgc ttttattaca agtaaaccag ttcccataca
    12841 aagcaagtta gagtcatatg tatatatttt accatctaca tcattctttg ccattacagc
    12901 actttgatac gtacctgtag ctgtggcaga ccctgctata taaagtatct ctctatcctc
    12961 atttgtatat ttctcaaaaa tttccttaaa ttgggcataa gtagcttgag aagtttttgg
    13021 atatacattt tcttctctaa gccttttata aaattcatct ccagatatat caattctatc
    13081 cttgtattct ctttcctcca gtataactgt taatgaaact atatctatat catatttatc
    13141 taacaaatct tttggcacgt ccgataaact gtcacagatt atctttagat ttttcattaa
    13201 gtatgctcct ttctcattta ggcttgttga aactacctca tatttgggta tcctatttgt
    13261 cttaaagcct cgtacactac aatagcaact gaatttgata aatttaatga cctagctttt
    13321 tcaacatcca acataggcac tctaatacaa gtatccatat ttgctttcaa caaaggttct
    13381 ggtaatccct ttgtttcttt cccaaatact ataaaacaat tttcttcata tttcacatct
    13441 gaatgtgact gtttagcctt tgttgtagaa aaaaagtatt tactatttgg atacttttct
    13501 tgtaattctt caaagctatc gtaatattgt atatcagcta tatcccaata gtcaagccca
    13561 catcttttta ggtgtttatc atccaatgaa aaacccagtg gttttactaa atgtaaagtt
    13621 gaacctgttg ctgcacaggt tcttattata tttcctgtat tttgaggtat ttctggttct
    13681 actaatacta tatttaatga cattttaatc ctccctaagt atcgctttta tttatcaaat
    13741 tttattttat aaacagaata acaataatat tatactatta tataaaataa tgttaataat
    13801 aatttttatt tcatgtatat aatagttttt tatctaacat tttcacaagt attattatat
    13861 cagaaaatcc ctcttgtaca acttactttc taaaagttat ttcgtttcat taagttcttt
    13921 ataataatta caatcttctt ttattgggca acttgcacat tctggatttc tagctttaca
    13981 cattcttctt ccatgaaaaa ttaatacatg atgtgagtgt gaccatcttt cttttggtat
    14041 agcttccata agtgcaaatt ctgttttttg aggatttggc tcgtccacta ttcctattct
    14101 attgctaact ctaaatacat gagtatctac agctattgct ggatgattaa aagcgttact
    14161 aagtacaacc cctgccgttt ttcttccaac accaggtaat tttataagct tttctaagct
    14221 atcaggtact tcaccatcat ataattcaca tagctgttca gatgtatcct ttattttttg
    14281 agacttgctt ttgtaaagac cacaactctt tatctcttta ctaatttctt caatgctcaa
    14341 attagcaaag tctctagctg tgttgtactt tttaaacaac tctgaagtaa ctttattcac
    14401 tcttacatca gtacattgtg ctgataaaat agttgctatt aaaagttcaa aggctgtccc
    14461 ataatttaac tcacatttag catctggata caatttttct aactcgtcta aaatcttatt
    14521 tacgtctttt tcatttgctg actcattttt aattttagac ttacttttag tttctttact
    14581 tgttttttgt gtagccttat tagaactact cttctttgtt tttttctccg tttcaccttt
    14641 tttagtactt tttttactta ctttgatact ttttttatct tcttcaatat ccataaaatt
    14701 ctctatatct ttctcatcaa ttatctcatc ttttttacca atcattttat ctattccttt
    14761 ttcatttatc tcttccttct caattatatc tttcttattc attccttttt tatttatctc
    14821 ttccttctca attatatctt tcttattcat tcctttttta tttatctctt ccttctcaat
    14881 tatatctttc ttatctattc cttttttatt tatctcttcc ttctcaatta tatctttctt
    14941 atctattcct tttttattta tctcttcctt ctcaattata tttttcttat ccattccttt
    15001 tttatttatc tcttcttcca aaattacatc tttttcattt atctctttta gatttacatt
    15061 tttcataatt atcccccttc aaaataccaa tttataaaac gctatttata aatagtttaa
    15121 tcatatcaac aaaaaaataa acatcaatat ataaaacata caaaataaga atttaattta
    15181 tatatattta caaaaaaagc aaaaacctat taaagttctt gctttttatt atacataaat
    15241 acccattaaa ttctataata aacttattct tttgacacag tttgtatctt gctgaaagat
    15301 attaattttt cttttaccaa tttctttatt tcttcaaatt taacatctgt caatatctct
    15361 atagcctctt ctactctttc aacagtatat atcttaaatt ttccatctcg cactgcatca
    15421 ttaacttcat ctgataaaac gagatttctt tgattttttc taggaattat gacgccttgc
    15481 tcaccattta accctttagt tttacatata gaataaaatc cttctatctt ttcacttata
    15541 ccaccaacta cttgtatatc acccttttga tttatagaac ctgtaacagc aatattttgt
    15601 ttaattgata ctccactaag agatgataat agtacatata attctgcaga agatgcacta
    15661 tctccatcta ttccaccata attttgttca aaacaaacat atgcatttag tgacaatagt
    15721 aaatcctgtg caaaattctc agaaagatag ccacctaata taagtactcc tttgttatgt
    15781 atagagccac tcatatttac ttctctttct atatttacta tgcctttact tcctgggcta
    15841 gtggtcgctg taatccttga agctctacca aaagagtatt ctcctgtact taagactgac
    15901 aaaccattta tcactcctac ttttcttccc tctgtttcta ttagagtaaa tccattttca
    15961 attgattcat ccatatgtgt ttccactcta ttgattcttt ttctcttttc acttattgct
    16021 tttttaacat cacactgctc tgtatactcc gaatttctaa actctgcata agcacttcct
    16081 tctattacaa cttccattat tttattaaac ttagttgata atttttctaa atcaccagat
    16141 aatctagtgc taaatttaat aacctcttca actgctgatt tagtaaaatg ccttaaatta
    16201 ttcttatcac attggtatgc tataaatctt gctattcctt cttcattatc ttcattttta
    16261 tccatttcac tatcaaagtc tacaaatact ttaaaatatt tttcaaaatc ttcatcatat
    16321 ctatataaaa tatcatatat atagtggctt ccaatcagta ctaatttaac atccaatggc
    16381 atattttctg gtttaattgc tgtttgtgtt tccaatatta cttttttagt ctgcaaagtc
    16441 tttttaagaa tttcccaaga cattgtatat tttagtaatt ggtctgcata aagtactaaa
    16501 taaccaccat tagccctatg aaatgctcct gataatagtt ttgtgaaatc agtctttata
    16561 tttccatttg cataatcata ctctgccttt ccaaatagat ttgctggact tgggtttatc
    16621 tctactacaa caggtgctga ttctttattc tttgagcttc cattgtctac aaataggtta
    16681 attttatatt taataaaatg ctctttatca tacttatctt ttaactcctc ttcatctaaa
    16741 tagaataaat acatatattc tattatatct ttctttatat tttccagata agtttgaatc
    16801 ttatcataat tttcatattt ttcacacaat ctcttgatat gaggttctac tacaagttta
    16861 gctatctctt cttcaagctc taacactgct ttttcagcta tttcttctaa gtttctaatt
    16921 ttatatacga cctgtatcgc catattttct agttctcttt tagctttgta aaactcttca
    16981 tcagactcat cactttcatc ttcctcttct ttcaaaggga taaaaactat tcccatttta
    17041 ctctgtttta atttaaatcc tttttcttct ccatattttt taatttgctt caaaagcata
    17101 tctttttcta tttcatattc atccagaagt ttattttttt ctatttcaaa attttcactt
    17161 tcaaacgcat ttttaaaatc ttctaaaaga ctttcaatta atttctccat atctttctta
    17221 agttctcttc caaacccctt ttctaattca actataatag gctctctagg gttttcaaaa
    17281 ttatatatat aacaccaatc tttatgcgta ttttttttgg atgcatactc atttaaaacc
    17341 tttaaggcat aagtactttt accagttcca ggttcaccag ctatatatat gttgtacgct
    17401 ggattattta ttttcaaccc taattccata gcttctacag ctctttcttg acccaatata
    17461 taatctagtg gatttatttc agatgtatta ttatatttca atattccccc acctccccat
    17521 atttaacttt aatgatataa tatgactttt acacaacaag tgttaaagta aatacacatt
    17581 aaagtatatg aaacagactc ttattattag tcatcatact tatctaaaat tatttccata
    17641 tttctcttta ttatatttct tcctctccag ctaaaagctc tatctccata tttcctttta
    17701 aattctttat ttgaaatatt ttgtatctca tcataattca aataatctat tatattttct
    17761 ttaaattcca aaatatgagt tgttggtatt tcaacattat gtggacatac ttcttgacaa
    17821 atatcgcatc caaatacctt tttgccattc tttaaaacaa ctttttcttt ctctgacaaa
    17881 tctccttttt tttgagttat atatgataaa cattttttgg ggttcatatc ataatttccc
    17941 aatatagcat ttcccggaca atattttaca cactttccac atttaaaaca acttttttct
    18001 agtggtttat cttcttcaaa tttataatta tttactatat accctataaa tacgtaagaa
    18061 ccatattcat cagttatgat attattattt attccaaaat atcctattcc tgataaataa
    18121 gctaaatacc tgtcaactaa tggtccatta tcagcaaata acttgtattt aaaatctgtt
    18181 actgttttag aaatataatc acaaatttgt tgtaaaaagt cctttactac aatgtgataa
    18241 tcctttccat gacaatattt tgataaattt gaatttttat tcttttcttg tctatttata
    18301 tgatatggaa atgcacagac tattatagag ttagcatcct tcattatatg tcttgggtta
    18361 attctgttct caattattgg ttcttccata ccagttaaat aacctttttg ttgtctgtcc
    18421 ttaagtatct tttctaaatt atcatactta tctacccctg ctactcctac acagtttaat
    18481 cctattaaat tacaaaatgc ttttaattcc ttattatcca taaaattatt cctttttaat
    18541 ctaattgact ttttaaattt atttaatttt tttagtcttt ttaacctttt ctagctacta
    18601 actcttttaa atacttaatc tttttagcta ttcaattttc ttacctactt aaatctttta
    18661 gatacttcgt ctttttacct atttaatttt ttacctacta acgcttttag atacttaatc
    18721 tttttatcta tttagttttt tacctactaa ctcttttaga tacttcatct tttttattta
    18781 ctaactcttt tagatacttc gtctttttca tttacttatt taactttttt atctacttaa
    18841 ctcctttaaa taattagtct ttttatctat ttaattattt tacctactaa ctcttttgaa
    18901 tacttagtct tttttattta tttaattttt ttatctacta acgcttttag atacttaatc
    18961 tttttatcta tttaattttt ttatctacta actcctttat atacttagcc tttttcattt
    19021 acttatttaa ctactaactc ttttagatac ttagcctttt tcatttactt atttaacttt
    19081 tttacctact taactctttt agatacttag cctttttaat ctattcaacc ttttttaccc
    19141 acttaacctt cttacctttt aatataaact ctaaaacttc aaatatcatt agttatattt
    19201 tgacattctt tctatagtta agcaaaaaga ttgatttttt cttataatta atatcccatt
    19261 tacattgcca tttattaaat ctttacttga cttatatgga tttcttttta ctctctttac
    19321 taaactatac ttattaatat tatgaaggtc ttataataga ctaatatgaa tatgtccatc
    19381 atatatcaaa ttttaaaatt tgtaagcaaa atacttatct tatattacta catctaaagt
    19441 ggaaaatttt acaaaaaagc tctgtaaaaa cactttaaat aacaatttgc ttttaaatca
    19501 tatacagatt ataataaata ctgtataagg atggtgaaaa atttgattaa aataacaatt
    19561 ccaggtagac ctattagtaa atctaatttt aagcttcata acataaatgg tcaagcatgg
    19621 atgccttcaa agggaaaata ttctaagtat cttgcatacg aaaacatgat tgcaggtttt
    19681 ataaaccaac agtatcaagg ggaaactgtc gaagaaaatc taataacagt cttgaaatta
    19741 ttcttcccaa ataagagaat gggggattta cataattatc caaaaagtat ttgtgatggt
    19801 attgaaaaaa gtggaataat aaaaaatgat aaacaactta agccagtact tttatttgat
    19861 tttatagata aagataaccc tagggttgaa attgaacttt atccagtatc taaatacgat
    19921 atatcctata atatttttga aaaataaaga ttttatgtgt tattcgacat tatattgata
    19981 ctccagtatt tgaaactata ctaatacaac aataataatt gtgttatgtc tatactcaaa
    20041 caaatgtttt taaaaagcat taagtaaata tttaataagt attaaacaaa tattaaattt
    20101 atataatagc tataactatg taaatttaat atttgtatat aagaccacat ctaataaaaa
    20161 gaaatcggag taaatttaat acaccgattt caataaataa aatctatcct agcttttcaa
    20221 caacagtctt aagcatttct cttataggaa gttcatatgg acatctactc tcgcaaagcc
    20281 cacagtcaat acactcagta ggtttaacat ccataacctc atatttttct ttagcccact
    20341 cttttaatcc atatctagta taataacctt cacataaaaa actcaatggt atatttattc
    20401 ctacagcaca aggcatacaa tattcgcatc ttctacagaa ttttttacct aaagaatttc
    20461 ttatttcttc aatttcctta ttatcttttt catctagcac aagattttca agtacagcga
    20521 cattttgtct aacctgttca acactctcca tacctggtat aactacatct atgtactctt
    20581 tagatagtat atatttaata gccagtgttg cattgtctaa agcacctcca gctaaaggtt
    20641 tcattactat tatcccaatt cctttttcat gagctttttt aaacacttca tctgcttgtc
    20701 cttcaactat attataaggg aattgtatag tgtcaaattt tccatcttct atagcttttt
    20761 ctatagtatt taaattgtga ctagttatac caatatgttt tatcttacct tgctcctttg
    20821 cctctaaaag ggcactataa gccattttat ctttaaaaag attatcatac tcctcttctt
    20881 taacattatg gaattgatat aaatctataa aatcagtttt aaaattattt aaacttattt
    20941 caacatctct cttcattgaa tcataatctc tggacatact tttagtagct aagaaaaatt
    21001 tatctctttt tccttcaatg gcaattccga ttgcttcctc acttattgta taccctcttg
    21061 cactgtcaat aaagtttatt ccttgttttt ctaactcatt tataactaag ttagtatcat
    21121 cttgagtaat cctttgtatt ggaatgcccc caaagccaac tctctttatt ttcatgttag
    21181 tattgcctaa atttctcata tctttcccca cctaactttt aataattttt tatataatat
    21241 aaatatgtca cctttaatta tacaacaaat tatgagaatc tttgcaatgt atttacatac
    21301 tattcataat ataattatat tttatatcag tctattcata atataatcat actttatacc
    21361 cagttaattt gtatacaatt ttcgttattc ctatccatta atttaaatta tcacatttca
    21421 tgattgtatc tccaccctaa ttatgttgag ggtggagtat ttcacatatt tttaataaag
    21481 gtttatttac tagatagtat ttcttttatc attttaagct ctctcttgtg accttcatca
    21541 tcaaaaggag tttctaagaa aaatggtaaa tgttttagac taggatgttc cataaaatca
    21601 attaatgctt ttaatcctat ctttccttcc cctataggag catgtctgtc ttttttgtct
    21661 ccaaatggca tcatactatc atttagatgg acagttttca atctttctat gcctataacc
    21721 ttatcaaatt cttccaaaac cccatctaaa tcattcacta tatcataacc agctgaaaaa
    21781 atatgacatg tatcaagaca cacacctatt ttttctttat gctcaatttt gtctattata
    21841 ctttttaatt gctcaaattt aaaacctatt tcagttccct ttcccgacat agtttcaaga
    21901 agtatagtta tattttcatc accctttatg gcattgttca atccttttac tattctatct
    21961 atgccaaaat ctacaccacc acctacatga cttccaggat gaaaacacat gtattcaatt
    22021 cctaatgagt ccatccttct tatatcctca tctatcaccc ttgttgcaaa ttcgtataca
    22081 tcatcctttg taccacccag attcatagta tatggtgcat gtgcaagcag tggtgcaaaa
    22141 ttattttctt ttctaatttc ttgaaattta attatatctt tttcatcaaa ttctttagca
    22201 tttcctcctc ttggatttct actaaaaaat tgaaatgtat ttgcaccaat atatacagct
    22261 gtctcagccg cattagcaaa tccttttgct attgaaagat gtgttcctaa tttaatcata
    22321 ttaatctcct tttatttgta ctactacttg tactcaattt taattttgaa ctactccacc
    22381 ttaactacat ttagccaaca tatgaagatg gagattccta tttgatagta ctttttcact
    22441 aaaaattcgt aagctctaag ggatgttcta tcccaactaa tctcattcct cttttaacat
    22501 atttctagca ttgatttaat ttatattaat ttttaatttt aatatttaca ctttaattat
    22561 acccatttta atcaatttca aatattataa tcttacatac tttgtatatt atctaagcac
    22621 ttcttagata gtgtatacat cttacactat acatattatt tacaaataca ataggtataa
    22681 aaaaacaaaa aaatagagat taaaaatcat tgttttaccc ataccaaaaa ctattttttg
    22741 attattaagt aaattttgat gttcaatctc taatattata tctttaatta atccataatt
    22801 aattctctaa ctaggacatt cctcctcaag agtaggaact ataaccatag ctatatcata
    22861 cttagaacct tcaacattgt gttgtctttt atttaaaatt tcatctatct ttgacttcat
    22921 agtgtcacta agttcaacta attcatcatg agtaagagaa atatcatgat aatcaactat
    22981 attttcattt tctaaaacat cttcctctgc tgccttataa aaaacttcac tcatattttc
    23041 aaattttgat atgtacaatt cttctttttc ttccccattg tctaaagaaa aattaagtat
    23101 cctattccct ataaccacat tttttgcact tggataatag tacttttcca caatccccga
    23161 ctttattttt tcctcaacta attctaaaat accaactttg tataacattt ttatatggta
    23221 gtttattttt gcatgaggtt cttccaataa ttgagataat tgttttgctg acaatggcga
    23281 tttgtcaaat gcttttagaa tatctattct acgtggatgc gcaatagcct ttatgcactc
    23341 caaatctcgt aataccaata cctctttcat tgacccctcc taaaaaattt atttaattca
    23401 tatttcttta caatttaatt atatattaaa ttatatgttg ttgtcaaaaa aatcctttct
    23461 taatatttta aaaaatattt aatttgagtt tatttgacaa ctcctctaaa actttaactc
    23521 ctgcgacgct gttacctttt ttgtcaagcg caggtccata aacaccaatc cccatgcgtc
    23581 ccggcacaga agccattata ccacccccaa ctccagattt tgcaggaatg ccaactttaa
    23641 tagcaaattc cccagaagca tcatacattc cacaagtcat cataaatgtc ttgacaatcc
    23701 tagaaaccat ttcactcatt aaatgctcac cattttctat atctactcca taatttgcaa
    23761 gatttattcc aattctcgct aaatctacag aatctatctc aattgagcat tgtttaaaat
    23821 aaaggtctag aacatcttct acattccctc tgataaatcc atcacttttc aataagtaag
    23881 ccatagctct gtttctatct ccagtcattt tttcagactt atagacatca tagtttattc
    23941 ctatattatc attttttgct aactttctaa agaaactaag cattctttct tctttttctt
    24001 ctaaacaact cccatttata agggaagtgg ttactatagc ccctgcattt atcattggat
    24061 tacagggttt ttttgtgtca ttaatttcaa gtttcattat tgaattaaat gggtccccac
    24121 ttggctccat tccaacgttt gaaaaaacgt cttcccaatc attatccata agtgccatag
    24181 caagcacaat tggttttgaa atactttgta tagtaaactt tgtgctacag tttccagcac
    24241 tataaagatt attttcgcta tctatgatac aaattcctaa atcatttctt ctagcgtttt
    24301 ttaattctgg tatgtaacta gcgacttgtc cataattagt atacttctta ttagaactta
    24361 taatttcttt taataatgtc tcatctaacg tattcatatg cacctcttat attatgttat
    24421 atattctatt ttagcacaag tttatactat aataaaacaa tgttaaaaaa aattatactt
    24481 taaaattatt ttctacaaga atcaattcat ttttcaaaca atttaaatag tttaaatagc
    24541 ttaataattt aataatttaa caacctagca atttagtaat ctaataatcc agtaatttaa
    24601 caacctaata atttagcaat ctaataatct aactatctaa taatccagta acttaacaac
    24661 ctagtaattt agtaattcaa caatctaaca attcaataat ttaacaattt aacaacctag
    24721 taatctaact atctaataat ccagtaactt aacaacctag taatttagta attcaacaat
    24781 ctaataattc aataatttaa caacctagta atctaactat ctaaataatc cagtaactta
    24841 acaacctagt aatttagtaa ttcaacaacc taataattca ataatttaac aacctagtaa
    24901 tctaactatc taaataatcc agtaacttaa caacctagta atttagtaat tcaacaacct
    24961 aataattcaa taatttaaca acctagtaat ttagcaatcc agcaatctaa taatccagta
    25021 atttaaattt ttataacacc aaaaatttct aacccaacac cttttactct tttactcttt
    25081 tactctttta ctcttttact cttttactct tttactcttt tactctttta aaaaataatc
    25141 acataaatta acaaaatatt aaacaaaaaa gtaaaattta aaataaaaag cttgcttcat
    25201 acaaaagtat aaaacaagcc tttttatata tcaactcaaa ctttaaaatc tgtatcaatt
    25261 taattctcca ctttacactt aatatactta acataaacca ataacactac ttgctatgcc
    25321 atttaatctt cataaaacaa tctataatac acacattaat caactatttt acttcctcca
    25381 ataaattccc taagaattga aatacctggt atgtcagaag tatcgtccaa ttcaacaaaa
    25441 tactgcaaaa actttagtaa tctagtagct tcaatatgtg caggattatc ttcctttatc
    25501 tcttccaaca aaggtttcgc aaatcgtttt aaaactgcca attcatatac acaagcagag
    25561 ttaaatatag catctgcctc ctcttggtac gggaatatat tcttcttttc tcctcttcta
    25621 actgatgccc attgtaaaat agtattatca gcactatatc ctctaaaatt atagtctcta
    25681 acaattcttc ttatcattct caaatcagca gtagggattc gattatggtc atccaaattt
    25741 atttgagtaa gggcacttat gtatatctta aatttatctt catctggtat agatgatgtt
    25801 aaaataggat ttagcccatg tataccttct aatataattg gctgatttga atctatcttt
    25861 atctttttac cagtgtattc tctcttacct tctttaaaat tgaatcttat atcatcaatt
    25921 tcttcaccag ctaaaagttt ctttaagtct aagttaaact tctctaaatc tattgcataa
    25981 attgattcaa aatcataatt tccatattca tctaaaggag tatgttttct atctataaaa
    26041 taatcatcta aagaaattga aataggattt aaattattta ctctaagatg tattgataat
    26101 ctgtgagcaa aacttgtttt tccagatgaa gatggagctg ctattaaaac tactctctta
    26161 ttgccatcct ttatcatatc cgctatttgg gataacttct tttcatgcaa tgcttcaaat
    26221 gtccttatta tatctccata ttcattgttt tctattattt tattaagaga tactaccttg
    26281 tcaattccca taagtcttga ccattcttct gcttcataat atacacttga tagcttaggt
    26341 tgaggtacaa atttcatagg aagagtctta tcttcttcac taggtcctaa aattataacg
    26401 cctccattat aaagcttaat atcaaatgat tttatataac cagttgatgg caacatataa
    26461 ccataaaaat ggtctatata gtttctacac ttatatactt tagcactatc atactctttg
    26521 tatttcaaaa gctctgcctt ttcatacatt tcattatttt caaagataga aatagcttca
    26581 tttcttgtaa cttcaatttt ttctataaca taatcgttgt ttactatctc tttcatcttg
    26641 ttttttatat tttcaacatc tgcttcttta agctttctat ctatatgaac ttcacaatat
    26701 agcccatctg atagtgaatg ttctattgta actctgctat cccaaaagat ttctctacat
    26761 gccattacaa atataaatga catgactcta aagtaaactc tctctccatc ttcattagta
    26821 gtatctaaaa aatttatctc acaatccttc ttaactctac aatttagctc ttttagttta
    26881 ttgtctacaa ctgcaagtgt tatataaccc ttatgctcat cacaaaattc ttttgctata
    26941 tctcccaatc tgattccagg ggaattttct tctaatgaat attccttatc ttttccttct
    27001 atttttaagt ttattttttt cacttcaaca tctccttcct tttgatgaat ataaatttta
    27061 attaatgagg catatcaaca agataaagag aggtatttaa ccctctccta caatattatt
    27121 caatttactt atagtatctt caatgtcttc gtaatttatt tctaatacta aatattctgc
    27181 atctaatgtt aagatctctt taatcccctc ttcagataaa attcctcttc ctataccaac
    27241 atgtgtatca ttgataccat cattatcact taagtgtatc agtcttattt tatcctttaa
    27301 gttctttaca taagcatcct catcaattaa acagtgtcca gtatcgtaac aaaaacaaat
    27361 cttagaattt ttaatcctct taaatatata ttcaaaatca taagatatat ttccaatatt
    27421 tgaaaaatcc ccaccttttg aataagtatt ctctatacat acatatgaat ttgtatttaa
    27481 tttatctaaa aaatccacac tatttcctaa atatttgtct ctattctttc taactctatt
    27541 tgtcataaca tatcccaaat gaaggttaaa ataccttaaa tcaaatcctt ttagttcaaa
    27601 ttctatcttc tcaataaaat ttatccatga atttcgtata tactctatgt tttcgcaagt
    27661 atttaattcc ataggcaaat gtatccctat agataatcct aacttagaaa ttctctcttt
    27721 atatttacat aactcactac attcagatat attgtcaatt ccaatctcta aatgagttat
    27781 ttgctttata ctctcacaaa tgtttaaagc ctcctcaata ttaaacaata aggacgctat
    27841 accaactgcc atacaaatca cctactcaaa aatacctata tctgtaaaag gaaatactct
    27901 taaaataact tttcctttaa tattttcttc atctactaat cccacttctt tatatctact
    27961 gtctaaacta acttctctat tgtctcccat cgcaaatact tttcccttag gaatcaccat
    28021 atcaatatcg ccttcagtat aattatcatg tatatatgaa acttcattta ataacttacc
    28081 atttatataa accttagaat ccttaatttt tagatggtca ccaggaacac ctataaccct
    28141 ttttacaagc tcttttttcc ttccattctc ttgtaataaa tcagtcttaa atatcattat
    28201 atctccacat tttggttctg ataacttata tgtcatcctg tttgctacca aataatcatg
    28261 tgatttaagt gttgggtaca ttgattctcc atttactaat gttggtttta taaaacgagt
    28321 tataataaat gcaaaaaaaa gtgcagtaat aattattttt atccactcta caatctcttc
    28381 tttaatagtt tcattcattc acaaattctc ctttatagtt atattatctt tattgataat
    28441 gtctcttaaa cactatcttt tagataagtc tactaaataa ggtgttgtct tttttatata
    28501 gacaactatt gtgtatggtc tggtgatttc agctaatcag cgattgctcc aaattttata
    28561 tgtttagtca atagttccta tcttagaaaa tggatacaat ctgactagaa cctttcctaa
    28621 aatggtatgc tcgtcgacca atccaacctc atcgtatcta ctatctaaac ttttttctct
    28681 attatctccc attgcaaata attttccttc tggaactacg atatcaatat ctccatcagt
    28741 acgattatta tgtatatagg aagtctcatc taacaactta tcatttacat ataccttgga
    28801 gtcttgtatt tttacatggt caccaggaac cccgataact ctttttacta aatctttttt
    28861 ctttccattt tcctctgtta agtcggtttt gaatactatt atatctttgt attttggctc
    28921 tcctaccttg tacgcaattc tgttaactat caaataatca cgttcaacta atgtaggata
    28981 cattgattct cctttgacta ttgttggcac tataaaacga gttattgcaa atgccaaaac
    29041 aagagctatg acaatcactt ttatccattc tacaacttct tttttaactg cttcacccac
    29101 taaaatcgtc tcctctgtgt taaatattaa gtcaatctac agcaaaataa tctaccataa
    29161 acctacaata taaatattat acttcttttt tctaatagtt taaaatactt ttctaagacc
    29221 tttaggataa tgattcttaa ttacaccaga agattctttt ccccaaccta aaggtattcc
    29281 ttcaaccgaa accaaaaccc atcctctact atcattagaa tttacaacat ccccttttaa
    29341 atatttaaga attgattcac tctgtacact gaagttttca acatttttta catcttcaac
    29401 ttttaagtaa tgagatagtg catgagaagg ctcaaatcta ttcttcttta aaacccctaa
    29461 atgcaaacca tatctcaata cttttagttt tttcgtatct ggatatattt caggaagtag
    29521 gtacaaattt tctcctctta aataaaattt atttttttta ttactataaa aatcaacctt
    29581 taaaaatttc ttttcaaact ccctataatc ctttatttct ttatctaaat tttttatttt
    29641 taattctttg acattacatt cttcttcttc taattttttt attttggcaa caaaatgacc
    29701 ttctcccttt atcttatgag gccataatct ttccatttca ataagttctg catgtggata
    29761 ttcactgata aactcattta taacatgctc attttcctcc cttgaaaaag tacaagttga
    29821 gtaaattaaa atgccatcct tctttaacat tttatatcca tctcttataa tctctttttg
    29881 gatggattga cattctacta cctttgcata actccaatct gatatggcaa cctcatcctt
    29941 cctaaacata ccttgcccag aacaaggtgc atctataata accttatcaa aatacccatt
    30001 aaacgtcttt cttaagctat tagaatcggt gtttgttata atacaatttc tcgctccaaa
    30061 tcgctctaaa ttttccccta gagccttaat tctactagca ttaatttcat tagaaaccaa
    30121 taaacctgta tcgtttagct tagatagtat atatgtagat tttccaccag gagcagcaca
    30181 catatcgaga actttttcac cctctttaat atctgccttt ggtattacac tcattgcaga
    30241 aggctcttgc aaatagtatg ctccagcctc atgcagtgga tttctaccag gtctgtcaat
    30301 tttatcatca taataaaaac cttcttctgc ccatggtatt tgattcaaat caaacaactc
    30361 caaatcaaat aattttttct tgtcaatttt taaagtattt attctaagcc cagtagtctt
    30421 actttcctca taacttttta taaaatcatc atattcatct tttagtattt cttcaatatc
    30481 ttctaaaaat tcctttggta attctgtcaa atctataatc ccccttcaat ctgctttact
    30541 tgtgtgtcat ttattatact ttaattattt atgtctttcc tttaaatttt atttcttctt
    30601 ctttttccta agattaccga aaaacacttt tttagagtga ttcatatatt tctcaagttt
    30661 atcaagattt atcttccaca aaattattac ataaactata agtaatataa tagcccatct
    30721 atattctatc atcaatatga aatcaaaaac tccatgtaat aaaattggaa ttaacaccgc
    30781 cataaacaaa tactcacgtc ttttattttt atttccctca aatttatact tagaaatata
    30841 gtagcccata gtaattgcaa acattacatg agctggtata gagataactg ccctattaat
    30901 accaacttgc agtgctagat ttctactttc agaaaaaata taaaccatat tttcaattgt
    30961 tgcaaatcct aaagctaaaa atacagagta aataatacca tctaactttt cagtaaagtg
    31021 tttttcttta attagggcag gaatcagtat cagagctttt acaccttctt ctacaagtcc
    31081 tgcaactaca aatgatacat atattagttc tgaataccct tcaaatacat taaacttcat
    31141 cagtaaattt tctaaaagta taattataac acttagaaaa gcacctatta aaaaaaattt
    31201 aattagatgg attaggggtt ctctacaata tctatcttta gaccttatcc aaaacatccc
    31261 tatcaatata ggaattattg ctaataaaaa taaatctagc ttcatagatt attttccttt
    31321 caaaattttt gatttattta tgatttatat catctactta tttttaactt attcgtgttt
    31381 taaatacata ctaaaatata cattaaatta ttttaaatta tttaaataca aatatactca
    31441 aatactcaaa aaaatttaaa tttatatcta tattatttaa caaatttcaa gctatattca
    31501 tatcttgaaa tataagggaa ctaaattcat ttaaagaaag ggtgatttga tgcaagatgg
    31561 tttcttaaca gtaagcataa ttgatgctac taacaataga cctattcaaa atgcagtagt
    31621 aaacatatat tcaatgtcta atggtagcca aagctcatca actttatacc aaaacctaag
    31681 aagtaatgaa tctggtcaag tgactggttt agtattacca gcaccagatg tagattactc
    31741 tctacaacca tctgatgtta gaccttatag ccagtatata gtggaagcca tagcagatgg
    31801 atatgagaca gttgtcatag aaggaacaca gttgttagct acaattgaag caagacaagg
    31861 agttcccatg tctcctagaa caagaagtaa gcgttctttc tcaagacaaa gtgagttgat
    31921 ttttgatata ggagaacata ctctatatgg tacttatcct cctaagattc cagaaagtaa
    31981 cttaaaacca ttaccacctc ctactggttt cgttgtatta gataaccccg tagtgcctga
    32041 atttatagta gttcatgatg gtttgccaga agattcatca gctccaaact attggattcc
    32101 atttaaagag tacattaaaa acatagcgtc atctgaaata tattcaactt ggcctgaaca
    32161 gacaatctat gcaaatgtaa tagctataat atcatttact ttaaatagag tctttactga
    32221 atggtataga aataaaggat ataactttac aataacttca acaacagcat acgaccataa
    32281 gtttataaat aatagaaact tatttgaacc aattaacgta gttgtagatg ctatttttaa
    32341 tacttttata aaaagacctc ctacatcaag acagccacta ttagcacaat attgtgatgg
    32401 acaaaaatcc caatgtcctg accaaatgac tcaatggggc agtaaagact taggtgacca
    32461 aggatatgac tatgagagta tactaagata tttctatgga gatgagatag tatttgaaag
    32521 agcacctata gtaagtggtg taccagtgtc attccctggt actacactac aagttggttc
    32581 ttctgggcag tatgttagaa ccatacaaaa tcagttaaat gctatatcta attcttatcc
    32641 agctgtacca aaagttatag aagatggtat ctatggaaca gatacagaaa acgctgttaa
    32701 gatattccaa ggaatctttg gtttacctca aagcggagta gtagatttta aaacatggta
    32761 tgaaatatcc agagtttatg tagctacaac tagaatagct tctttaaatc ctttaattta
    32821 aagcttgatt tagaacataa actcaaatta ttgaataaaa ttattaattt aaaataaaag
    32881 tggctgttat gaactaatat ataccataag tattacttat aagtattgta gtcttaacag
    32941 ccatttttta gttataactt gtttttttag aatcttaaaa ctttaaatgg gggattttaa
    33001 gcttcttaaa aacagtgctt agcaacttag atttctttaa aatattatat ttatttttaa
    33061 gtttaataaa atgctattct aacgaaaaac ctacttttta tttaaaatct cacttattat
    33121 ttaaaacact atccatcact tagaatatta cttcttatat aaattattat ttattataaa
    33181 tacaaataat attaatttaa aaagttattc ctaatttaaa taatactact atcttcatca
    33241 gtgaacctaa actgcaactt tagacttatt agctaaagcc aatattagac ctaaagctat
    33301 agatgcaaat gcagaagcaa ttactctata ctcagcaggg aataaaaata caattgtatg
    33361 acatggtatc cagaaaaatg gtatagtttt taaaacacta aaaccaaggt aagcattcca
    33421 gtccacaata tttaccacat ctttaagttt taccttaatc ccctttccaa cctcatattt
    33481 tttatctata aaacagtcca taaccttatg gaataaaaat acagttggtg acattagtat
    33541 attcatagtt gcactcttaa atagagcatt tgcaaaagct attccctcaa atggaagcat
    33601 accatccact tgtgcttgac ctacacctga tgagtagatt gacattccat atgtggtaac
    33661 tacacctatt attccccaaa ctattgctct ataaaatact cctactggta ttttccaatc
    33721 cttatacaaa attctaacac caagtaaatc tcccattgta gctaatacag caaactttaa
    33781 aaaacctcca atatatggat gtgcacctgt tgcttccata aatacttctc tactacttgg
    33841 tattgctaag acagcaataa tacaaataag aactccactc catataaaat cgcctttttt
    33901 catatttata aatactattt aatatataaa tagttctcct ttctattaaa gatttattta
    33961 atttacaatc tatctacaat tatttattaa tcacttatta ttagatattc attttccata
    34021 tttaaattta ttctatccct ttatctattt attttcttac tactctatcc accattatct
    34081 atatatttat tttacgatta ctctttcacc ctaacccttt aactatctat tttttcttac
    34141 tattcttatc cacatcatcc atatatttat tttacgatta ctctttcact ctaacccttt
    34201 aactatctat tttttctgat attcttatcc accatcatcc atatatttat tttacgatta
    34261 ctctttcacc ctaacccttt aactatctat ttttttctgg tattcttatc tactattatc
    34321 tgtatattta ttttatgatt actcttttaa cctaccccct atactttata gtaatatgtt
    34381 tttaaccttt ttcattattc ccaatatgct ttataactac aaatactctc cccccttaaa
    34441 aataataata aaattaatca ataaatttat aatcatatta ttactctatg tattaagcaa
    34501 ttactatgcc aataaacttt gattttttta aacaaatctt aaaaatccta aaatgctaat
    34561 tttctttaac ttttaatgaa tctaatagat aacatttaat tttcgttata tttttcagaa
    34621 tatttctatt attattttta agaaaaaaaa ataatgttaa catttcttaa catacattaa
    34681 aaaatgttaa cattataaat tgggtttaat acttttactt tgactcgatt tacttttatt
    34741 ctacttctta ctttattttt aacttagact ttattttttt attacttatt tgagtcttat
    34801 ttattttatt ctcactccat atgttcaatt acatttgtct aaattctttg atacttttat
    34861 tacataattt taacaagctt aagtgttatt tgggtagtgc agttgataat tatttaaata
    34921 atcatcaact gcatgtttat atcattacag tagcttaatg tatttaatca tacttactta
    34981 ggattttgaa atatcttaga gattatattt aacattagtc aattgctgca taattgtaag
    35041 caattgaaat ttgagaccca tcttcatttt ctatagtgat aggcttcata atttttaatc
    35101 cttcagtttt tatcttttct aattcttgtt ccattttctt aattgtttcc tcaaggtctt
    35161 tttgacttac atctttgact gcattagggt ctttagcata gtcttttaat tcttgaatat
    35221 gtttagcata ctcttcataa gtataatgct caacaccata cttttccaat tcagtagggt
    35281 cagttattcc tgattttatt agagattcaa atttaggtaa agcaatatta gatgaatcat
    35341 ttccatttgc aaatactgct ccagttcctc ctagtaccat tgcagatacc atcattgcac
    35401 ttataaggga tttttttatt ttcataacca atcttccttt cttagagatt tatttgggta
    35461 gtgtagttta aaatgactat tgcaatagtt atcaactaca ctcttagact atcacagtag
    35521 tcatgtttat gtcaagcctt tttaaaaaac ttttcaataa aaaatactat ctcaaagcaa
    35581 aattaattat tttgagatag tattttaatt ctaaatcttt tatattacta agatttatgg
    35641 ttattctatc catgttctat attgttcttt attaactgct aacaaattcc cttttcttaa
    35701 tatgacaaag cgattatcat tatagccact tcgctcaatt gaaacttctc ctgaatcagt
    35761 ataaagtaca tccttactat tactagattt atttacatac gtttcttcac tattctcaga
    35821 attagttact ttgctcatag atgattcttc atgctctcta aattcaatta cagatacttt
    35881 tgccgtacta aaatgagtct ctccatcact tttagcttta ctaacaagaa tatcagattc
    35941 tactttggga gaatataaat cagttgattt actacttatt gaaaatccaa ttttatcact
    36001 ttgttcattt tttgttaaac caaaagattc aacctcatta atctctttat tttctgttgc
    36061 aaaaacaaga cctgtcccac aaactaatac agttgaaact aaaaaagtaa cataagttga
    36121 ttttttaaat ttcataatat taactattct cttttctatt tttgtctttc caaatccact
    36181 acatattgtc attgaaaatg gattattctc ctctgctaga cttattagtg tggttgcata
    36241 atcagcccta tattcttcac caagtatact cataaccttt tcatcacaac taaattctat
    36301 gtctttattt agtaaaaaaa acatcaccca aactaaggga ttaaaccaat ggacaacaag
    36361 agctacaagc ataaataact ttaacagatt atcaaagcta ttaatatgaa ccatttcatg
    36421 agttaaaaca aagtctaaag tttgattatt agcataattc atttgctttg gcaaaataat
    36481 tcgtggtttt aaaataccag atgtaagtgg tgtcctagta aattcagata tgcaaacaat
    36541 aaatcttcta aaacggctat tcttacacat ccatttttta atgaactcat gattttttat
    36601 atgaattgaa gttttaaaaa gattaattat tttaaaatat ctaaagcata aaagtatgct
    36661 aaacataata gtaactataa aagacaaaat gcccaacatt tccaacatca taatattttc
    36721 aatattagac attatttcaa attcgtcaga attgttttta cctgtagagt cactagcttt
    36781 cttaagagta taattttctg ttgatgtatt acccaattcc acatcaaaag tcgattcaat
    36841 tatactataa atactaaaac cagaatttaa acttactggt attagaagtt taaataaaac
    36901 aatcaaccac aataatacaa ataccttttt aggtaatttt ttaaataaac atgctcttat
    36961 aaaaataact attaaaagta atactccaga agtaaaactc atttctaaca atttaatgaa
    37021 cataaatctt acctcacttt aatttttcaa caatttgttt aagttttgta atctcatcac
    37081 ttgaaagatt ttctttatta ataaaagctg aaagaaattt ttctgaagac cctccaaaca
    37141 ttttattaat taaagtttct gtttcctgtt tttgtacttc ctctttgctt attaaagctt
    37201 tacaaacaaa attcggctca attctctcta ttgcaccttt tgacactaat ttttttataa
    37261 cggtatacgt agtgtttcta ttccatcctg tttcttcttt taaaattttt actaactctc
    37321 cagccttgct ttctcctctc tcccatagaa cttccattac tttaagttct gaatcaaata
    37381 attttatctc catataaaat cgctcctcaa atatagttat cacaatagtc attactataa
    37441 taaaaaacta tcatagtagt ctatactatg tcaatcattt attttttaat aataaaaact
    37501 gtctttttaa aaaattctta taaaagacag ttttatcaat gttatacttt aatgtttaat
    37561 taaagccata ttttatttaa atatataact atctatctta gtacatagta taagattttt
    37621 ctttatctaa tagtatatcc tctacatctg ggttttcttt tactaattgt ctataaaaat
    37681 tacaattagt aacacccaca tatggaatta gccatagtag acctattcca agagtagcta
    37741 ttgaaagtat ataccatcct ataaagctaa agtttagtac aaataattta agtacatttc
    37801 ctttcatcat atctaaacta gcacccattg atttaaatac acccatatta tccttgtctt
    37861 cacaaattaa gaaagtagct tgagaaacat ataatagcaa tatataaact ggtaacataa
    37921 gaacaagtat tataagaact agagttattc cagtagaaat aatagtccct attccaacat
    37981 tatcacttga taaatattca attgctccac tagtaagtaa aactccaaat gataaaaacg
    38041 ctcctataat tgtgattata aaagaataaa tatacacaat aattgattca aataaataaa
    38101 aaccaaaact tcttaaataa attctcccac ttacaaagat atctcctatc ttgacttttt
    38161 catctttagt aattttcaag aacatacatg taaatcctgc tgaaacgcaa aaagctatta
    38221 cagccactac aatagtagtc aatggttcaa aaggtaatcc tacaattgat attaatacta
    38281 tcaatgcaat atatactgcc atagaaattg cacatatccc ccagtttcca gataactgag
    38341 ctttagatac tcgttttaat tcttgccttg ataccataaa aaacacccct ttcattttat
    38401 aaaaaaactt ttaaaaatat aaataatctt ttaacgtata atattaatat atcatatttt
    38461 cgactatata agatacaatt attcaccatg ttttatcaag atatgccata attgtattac
    38521 tagttttata tagtcaacat taccaaatac atcaaataaa tttgattaat tattcaacaa
    38581 gtaataaaat aa
//
LOCUS       DAMJWC010000037        38022 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMJWC010000037 DAMJWC010000000
VERSION     DAMJWC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.037"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            197..1381
                     /locus_tag="PC503_002128"
     CDS             197..1381
                     /locus_tag="PC503_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528100.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1758..2867)
                     /locus_tag="PC503_002129"
     CDS             complement(1758..2867)
                     /locus_tag="PC503_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2528101.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3330..4523
                     /gene="nifV"
                     /locus_tag="PC503_002130"
     CDS             3330..4523
                     /gene="nifV"
                     /locus_tag="PC503_002130"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF2528102.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4548..6473
                     /locus_tag="PC503_002131"
     CDS             4548..6473
                     /locus_tag="PC503_002131"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF2528103.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6495..7490
                     /locus_tag="PC503_002132"
     CDS             6495..7490
                     /locus_tag="PC503_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF2528104.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7815..8288
                     /locus_tag="PC503_002133"
     CDS             7815..8288
                     /locus_tag="PC503_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2528105.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8322..8816
                     /locus_tag="PC503_002134"
     CDS             8322..8816
                     /locus_tag="PC503_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2528106.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8913..9434
                     /locus_tag="PC503_002135"
     CDS             8913..9434
                     /locus_tag="PC503_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2528107.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            9623..9934
                     /locus_tag="PC503_002136"
     CDS             9623..9934
                     /locus_tag="PC503_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2528108.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9962..10648
                     /locus_tag="PC503_002137"
     CDS             9962..10648
                     /locus_tag="PC503_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2528109.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10880..11764
                     /locus_tag="PC503_002138"
     CDS             10880..11764
                     /locus_tag="PC503_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2528110.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11863..13038
                     /locus_tag="PC503_002139"
     CDS             11863..13038
                     /locus_tag="PC503_002139"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF2528111.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13166..14020
                     /locus_tag="PC503_002140"
     CDS             13166..14020
                     /locus_tag="PC503_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528112.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            14064..15299
                     /locus_tag="PC503_002141"
     CDS             14064..15299
                     /locus_tag="PC503_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF2528113.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15400..16341
                     /locus_tag="PC503_002142"
     CDS             15400..16341
                     /locus_tag="PC503_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF2528114.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16560..16913)
                     /locus_tag="PC503_002143"
     CDS             complement(16560..16913)
                     /locus_tag="PC503_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2528115.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            17209..18120
                     /locus_tag="PC503_002144"
     CDS             17209..18120
                     /locus_tag="PC503_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF2528116.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            18380..18814
                     /locus_tag="PC503_002145"
     CDS             18380..18814
                     /locus_tag="PC503_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528117.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            18837..20372
                     /locus_tag="PC503_002146"
     CDS             18837..20372
                     /locus_tag="PC503_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528118.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            20456..21823
                     /locus_tag="PC503_002147"
     CDS             20456..21823
                     /locus_tag="PC503_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528119.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            21858..22082
                     /locus_tag="PC503_002148"
     CDS             21858..22082
                     /locus_tag="PC503_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF2528120.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGVTMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(22532..22930)
                     /locus_tag="PC503_002149"
     CDS             complement(22532..22930)
                     /locus_tag="PC503_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF2528121.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(22933..23334)
                     /locus_tag="PC503_002150"
     CDS             complement(22933..23334)
                     /locus_tag="PC503_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2528122.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23694..24680
                     /locus_tag="PC503_002151"
     CDS             23694..24680
                     /locus_tag="PC503_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528123.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            24664..25575
                     /locus_tag="PC503_002152"
     CDS             24664..25575
                     /locus_tag="PC503_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528124.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            25688..27256
                     /locus_tag="PC503_002153"
     CDS             25688..27256
                     /locus_tag="PC503_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2528125.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            27331..28356
                     /locus_tag="PC503_002154"
     CDS             27331..28356
                     /locus_tag="PC503_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528126.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            28349..29293
                     /locus_tag="PC503_002155"
     CDS             28349..29293
                     /locus_tag="PC503_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528127.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIDVSDGHFVYSSKSEINKYQQNLKVV"
     gene            29652..32309
                     /locus_tag="PC503_002156"
     CDS             29652..32309
                     /locus_tag="PC503_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2528128.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFWVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            32524..33153
                     /locus_tag="PC503_002157"
     CDS             32524..33153
                     /locus_tag="PC503_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528129.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            33288..33614
                     /locus_tag="PC503_002158"
     CDS             33288..33614
                     /locus_tag="PC503_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2528130.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            33630..34919
                     /locus_tag="PC503_002159"
     CDS             33630..34919
                     /locus_tag="PC503_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2528131.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            34943..35272
                     /locus_tag="PC503_002160"
     CDS             34943..35272
                     /locus_tag="PC503_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2528132.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            35420..36748
                     /locus_tag="PC503_002161"
     CDS             35420..36748
                     /locus_tag="PC503_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2528133.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            37065..37925
                     /locus_tag="PC503_002162"
     CDS             37065..37925
                     /locus_tag="PC503_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF2528134.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEIEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
BASE COUNT        15021 a         3963 c         6808 g        12230 t
ORIGIN      
        1 aaaacaaagt gaatttgaat actatttaaa aaataaaata aatatataaa aaatatttaa
       61 tataaaggtg gaaataagtt gaaaatgtaa agtcattgga aaaatatagt tgaatttaat
      121 gagcaaaaat gttattgttt tatcaataaa gtgttaaaat aaaaactttc aatatcattt
      181 tagggaggat gatttcatgc aaaaaagtgt aaagaaagca aaagtaacgg gctctatgtt
      241 agctattttt ggtgttgcaa gcgttctttt tagttcacat gcaggaggag gatttgctac
      301 agggaatcaa gaaactcagt actatgtgca gtatggatgg acagcaccac ttatggcaat
      361 tttagcaatg attatactta ctgctaccat gagagaagtt atcataatgt ataataataa
      421 caattgtagg aattataagg atttattttg tgagctttgg agaccatatc caaaacttga
      481 aataatatgg gagatatatt actatctaat ggttttaata gctgtaagtg ctgttatagc
      541 aggtgcagca gcagtatttc aaagtatagg agtaaattat tttgtagctg tatttattat
      601 tggagttgta cttcttgtct ttactatatt tggtgctatg cttgtatcta aagcagctac
      661 agcaatgaca atagctattc tagtatgtac tcttactatt tttattgttg gtataaaagc
      721 taaagtacca gaaataactg aaatattatc aaatagaacg agtttcacac ctggctatat
      781 caagccaata cttaatactt ttatttatgc aggttttcaa tcggttgtta tacctacact
      841 tgcaggatgt tcaagaccac ttcttaagaa ctcaaaagaa gctactaagg caatgataat
      901 ttcatttgtt atgaatgcaa ttgcattagg acttgctgta actatgctaa tgggatggta
      961 tagagaaatt attgctgctg ggcaaacaac actccctact ctttatgttg caggtcaatc
     1021 tggaaatcat actatataca taatttataa tgttgcatta ttcctttgtt taatgtctac
     1081 aggagtaact actatatttg gtcttgtaaa tagatttgaa gaccataaag cactttcttt
     1141 cctttcttca agaatgaaaa gaagggtatt tacagcttgt gcaataatgg tagtgtcaat
     1201 gcttatatca cttacaggat taagtaatat tgttaaatat ggatatggat attgtggtta
     1261 tcttggtcta ttcactatag taattccatt tcttacacta ggacattata agaataagaa
     1321 gtttgcaaag gaaaatccag aagctaaatg gccagcggaa ttaaatgaaa atgtaaatta
     1381 gatgtagtag caaaaaatat tgctaaagag aatactataa ataagaatac tatagataat
     1441 atatctgcat gtttattaag attatttgca aaatctaata ttaaacaact ataaacaagc
     1501 aatataaaac taagaataaa agataaaaag agggtatctc aaaatggact tttagtttat
     1561 aaggcactct tttttatatg aagtcaaata tattttcatt attttgacaa taaaagagac
     1621 taatcctact ttggatagcc tcttttttct ttaatataaa atagtataac agcaaagtat
     1681 agattgatac atgttttctg tagctttcta tatattacag tgtttgtgtg gcattggtat
     1741 tttaagcaat ctataaatta taattctata attcttctac taattttaga ttctatagcc
     1801 gtctctattt cacttaacat tcgttcattt ttagggtcaa taaaagcaca tgtatagcct
     1861 tcttcaccag ctctaccagt tctaccaata cggtggatgt agtcttctgg tgtttctggt
     1921 aaatcgtaat tatatatatg acttactcca gatatatcaa gaccacgaga agctacatct
     1981 gtagctatta agtattgtat atctaaattt ctaaatgatt tcattattct ttctcgtttt
     2041 gattgagcaa tatcactatg aagtttttga caattatatc ctcttatagc aagagcttct
     2101 tcaagattgt caacccttct cttagttcta caaaatatta ttgccataaa aggattatct
     2161 tcatctagta ccttacataa ggcatctaat ttttttctat ctgtagtttc tactacttct
     2221 tgttttatat tattaagagt gatttcttct ttttgaatag aaactacaac aggatttttt
     2281 gtgtatctat aagctaattt ttttacttga gaatttatag ttgcagaaaa gcatagtgtt
     2341 tgctttttgt ttgaagtctc ttttaaaata gcttccactt catttttaaa tcccataagc
     2401 aacatttggt ctgcttcatc taaaacaaaa gtctttaact tactaaggtc tattgttttt
     2461 ctatttagat ggtctaaaag cctacctggt gtagctataa tcatatgaat atttcctttt
     2521 agtttcttta tttgagaacc aatatctttt cctccatatg ctgcaagaat acttacatct
     2581 ttagattctt taagtttcat agcttcttct gttatttgaa tagctagttc tcttgtagga
     2641 gaaagtataa gtacttgtat atcatttata tctaatgata tattttcaaa tatcggaagt
     2701 aaaaaagcta gtgtttttcc tgttccagtt tgagcttctg ctattacatc ttttccttct
     2761 tttattagtt taatactttc tttttgtata ggtgtaggtg ttgttattcc tgattttttt
     2821 agaatattta ttgtattttc actaatccct aagcttttga aatccattgt tatcttacct
     2881 ttcatgaaaa attttctttt ttattaacca attaataata tcatatttgt aagtattttt
     2941 agtaaatttt ttaattatta tttatatagc ttaaaaatat attaagatac tttaaaatgg
     3001 aatgtaactt aaattaaatt ttagtaggaa ttttataggt ttatttttaa aggttttttg
     3061 aaaataaatc tatttaaaaa ttaaattaaa atgcaagaaa aacataataa ctttcatttt
     3121 taagaagttt tcacaaaaaa gaaaaaatat agtgcaataa atgatacaaa gtaatataat
     3181 agattacaag atatgaaaag ctaaaaaaat aaattgcaaa tgaaattaaa atgaataaaa
     3241 aataaaaaaa taatcataag ttagaagtat caatgaaaaa taagacttaa tgtttttaaa
     3301 attaaaagta tactaagggg ggcattaata tgtgcgttat atcaaaagat agagcaaagg
     3361 aaataaaaat agtagatact actttaagag atggagagca aacagctggg gttgtatttg
     3421 caaatagaga aaaaataatg attgctgaaa tgttaagtga cctaggtgtt gaccaaattg
     3481 aagttggtat acctactatg ggtggagatg aaaaaaatgt aataaagcac atatgtagta
     3541 gaaatttaaa atcagatata atggcttgga atagagcagt aataaaagat gttgaagaat
     3601 ctatttcttg tggtgttgat gcagtagcta tatcaatatc agtatctgac attcatatag
     3661 aaaataaatt gagaacttct agaggctggg ttttagaaaa tatggctaaa acagttgaat
     3721 ttgcaaagaa aaatggatta tatgtttcag taaatggaga agatgcttca agagcagata
     3781 tagacttctt aactgaattt ataaatgttg gaaaacaagc aggggcagat agatttagat
     3841 actgtgatac agtaggagtt atgaatcctt tttctataaa gaatgcaata gaaactcttt
     3901 atgaaagaac taattttgat atagaaatgc atacacataa tgactttggg atggcaactg
     3961 caaatgcact tgcaggaata gcagcaggag caaattatgt tggtgttaca gtaaatggat
     4021 taggtgaaag agcaggaaat gcagcattag aagaagtttt aatggcactt aagtgtgttt
     4081 ataaatgtga tttaaataat atagatacta gaaaatttag aggaatatgt gagtatgtag
     4141 cacaggcatc aggaagaata cttcctacat ggaaaccagt agttggggat aatatgttta
     4201 tacatgaatc tggtatacat gcagatggag ctttaaaaga cccacataac tatgaaccat
     4261 ttgacccaag tgaagtaaat cttgaaagaa aaatagtaat aggtaaacat tcaggaagag
     4321 ctgcagttgt aaataagttg agtgaatatg aaatgtatat ttctccagaa aacgctacca
     4381 agctattaaa tgctataaga gctacatcta taagattaaa aagaagttta atggataaag
     4441 aaattcttca attatattgt gatatactag cacatgagaa aggcacaaca gaagaagaag
     4501 cagttagagg ttcatatatt taagatataa ttgtttagga ggaaaatatg ggagataata
     4561 tagtttataa aataattaaa aaacatatag tagatggaga agctgttgct ggaagttcaa
     4621 ttggtataaa aatagaccaa actttaacac aagattctac tggaacaatg acatatcttc
     4681 aactagaagc tatgggaata gataaagtaa agactaaaag aagtgtggca tttgtagacc
     4741 ataatatgtt acaacaagga tttgaaaatg cagacgacca taagtatata caaacagtgg
     4801 cagataaata tggagtttat ttctctaagc caggaaatgg tatttgtcat caagtatttt
     4861 tagaaagatt ttcaacacca ggagatacac ttttaggttc tgatagccac acacctactg
     4921 ctggaggtgt gggcatgatg gctattggag ctggtggatt agatgttgct ttagccatgg
     4981 caggaggagc atactatata aaagcaccaa aagtctgtaa ggtgaatcta gttggaaaat
     5041 taaataatat ggtatcatca aaagatataa tattagaagt gttaagaaaa caaactgtaa
     5101 aaggtggagt aggtaaagtt tatgaatatg gtggagaagg tgtcaaaagc ctatctgttc
     5161 cacaaagagc tacaataaca aatatggggg ctgaacttgg agcaactact tcaatcttcc
     5221 caagtgatga aaaaacacta gaatttttta agagtcaagg aagagaagac gcatgggtag
     5281 agctaaaacc agatgcagat gcagtttatg atgaagagat tactataaac ttggatgaat
     5341 taaaaccatt agctgcaaaa cctcatagcc cagacaatgt agatgaagtt gaaaatatag
     5401 gcaagattaa aatagaccaa gtggcaatag gaagttgtac aaattcttct tatgaagact
     5461 taatgaaagt agcacaaatc ctgaaaggaa ataaagtaca taaggatgtg agtttggtaa
     5521 tagcaccagg ttcaagacaa gttatggaga tgattgctag aaatggggct ttggcagata
     5581 taataagtgc tggagctaga atactagaaa attcttgtgg tccatgtatt ggtatgggtc
     5641 aatctccagg tactgactct gtgtctttaa gaactttcaa tagaaatttc tatggtagaa
     5701 gtgggacttt gtcagcacaa gtatatttag taagtccaga agtggcagca gtaagtgcaa
     5761 tcaagggagt gcttacagac ccaagagaat ttgatattaa atttacaaat ttagatgtaa
     5821 atgagttttt gatagatgat agcatgataa ttaaacctgc tgatgtagga agtgatgtag
     5881 aagtagttag aggacctaat ataaaacctt tccctcttaa tacagagcta agtcagtcta
     5941 taggtggaaa agttatatta aagacagaag ataatataac tactgaccat ataatgccat
     6001 caaatgctaa gttacttcct tttagaagta atataccgta tcttgcaaac tattgtttca
     6061 atactgtaga tacagaattt cctcagagag caaaagacaa taatggtgga tttatagttg
     6121 gtggagataa ttatggtcaa ggttcaagta gagaacatgc agctttagca ccattatatc
     6181 taggtgttaa aggggtaata gttaagagct ttgcaagaat ccacaaggct aacttgataa
     6241 atagtggtat aattccaatg gagttttgtg atgagaaaga ttatgaaaat atatctcttt
     6301 tagataatct ggagatacca aatattttag acaatctagg tagtggaatt ttagaagtta
     6361 agaatacaac taaaggaact tcttttaagg tcaaagtaga attgtcagca aaagaagttg
     6421 atgtattaaa agctggtgga aaattaaact acactaaaaa tcaagctaat taatatgaaa
     6481 agagggaata ttgaatgtat aaagtgacac ttataccagg agatggaata ggaccagaag
     6541 ttgcgaaagc tatgaaaaag gtagtagaag ctactggagt agaaatagaa tgggaagaag
     6601 ttaatgcagg agaggcagtt attgaagagt atggtactcc acttcctgaa tatattatag
     6661 atagtataaa aaagaacaaa atagctataa aaggcccaat tactactcct gtaggtaaag
     6721 gatttaggag tgtaaatgta actttaagac aggcattaga tttgtatgtc aacttaagac
     6781 ctattaaaag ttttaagggg ataaaatcaa gatatgaaga tgttgattta gtggttgtaa
     6841 gagaaaatac agaagattta tatgctggaa tagaacataa aataggtgat tatgcagctg
     6901 aaagtataaa gataataaca agaagtgcaa gtgaaagaat cgttgatttt gcatgtaact
     6961 atgttaaaga taataagaga aaaaaagtta cagctataca taaggcaaat ataatgaaaa
     7021 tgtctgatgg attgttttta gatgtgttta gagaagttgc atcaaaacat ggtgtagaat
     7081 atgatgattt gattgtagat gcagcagcta tgaacttagt tttaaatcca gaaaattatg
     7141 atgtaatggt aatgccaaat ctttatggag atatactatc agatttaggt gctgggcttg
     7201 ttggaggttt aggtataatt ccaagtgcaa atattggtaa agattgtgcg atatttgaag
     7261 ctgttcatgg aagtgctcca caaatagcag gtcaaaataa ggctaatcca acagcactta
     7321 ttcaatcatc agtaatgatg cttagatact taggtgaata tgaaaatgca caaaaaatag
     7381 aaacagcttt agaaaaagta tttcttgaag gaagtaaatt gactgtagat ttaggtggct
     7441 cagcttctac tacagagttt gcggatgagg tgtgtaagta tattgtatag attttattta
     7501 gggaaaaagt aaaatataga ttgaagaaaa gaggctttct caaaatagag ataagccttt
     7561 tttattggaa tgataaaata tatttgattt tatacaaaag agagttcctc ataaacgaaa
     7621 aagttaattt tgggatatcc attttaattt taaaattaat tgattaatac gcaaagaaag
     7681 attaaataaa tttattattt ttaattgaac tttcaaccaa aatatggtaa aatttaaaaa
     7741 gttgaacttt caactaaaaa tgaaaatatt gattatgtga aattctataa aacagaaact
     7801 atttgacttt agccatggta gtttcagtgg aggtgtgttt gattaagact ttagatagta
     7861 atatattaag agaagtaggt actttatcta gagcagtaaa ttcaataaat gatattaagt
     7921 acaaggaatt aaagttacaa aaaggacaat ttacattttt gacaagaatc tgtgaaaatc
     7981 ctggtataaa tcttgtggaa ttatcaaata tgttaaaggt agacaaggct acaacaacca
     8041 aggctataca aaaattaata aaggcaggat atgtagataa aaagcaggat aagtttgata
     8101 aaagaggata taatttaact ccaactgata aatctttgga agtttatgag ttgataattg
     8161 aagaagagaa tagaagtata gagatatgtt ttgataattt tacagatgaa gaaaaacaag
     8221 tggtaactaa gttattagaa aaaatgagca aaaacgtaga aaatgaatgg tttaaagtaa
     8281 agagatagta aataaataca ttaacttaag gagatatttt tatgattaga aaagcgaata
     8341 tgaatgattt agaaagcatt atgaaaatta taaaatctac agtggaagaa atgaagactt
     8401 ataataatac acaatgggat gaaaactatc cattagaaaa agactttgtt tcagatatta
     8461 agaaacaaga tttatatatt tatgaagtgg atggagaagt agcagggttt atatgtctta
     8521 attatgaaga gccagaagaa tatttaggct taaattggtc atctaataaa aaagcaatgg
     8581 taatacatag aatggctgta aatccaaact ttagaaagac aggaatagca tctaagttag
     8641 ttgattttgc tgaaaaatta gctgtagaaa acaatgtatc atacttaaag agcgatacat
     8701 attcaataaa ctcaaaaatg aatttattac ttacaaagtg tggttttata aaaatcggag
     8761 aaatgagttt tttaggaaag gagaaatctt tctactgtta tgataaaata ttataaagag
     8821 catttataat acaaggggta aataatagat tttcagcatt agtaagggca taatataacc
     8881 tagtatatgc tattatgaaa gggatgattt atatgattgg atttctaaag aaaagaagaa
     8941 gtattagaaa atacaaggat gttgaagtag aaaaagaaaa attagataaa atattaaaag
     9001 ctgctctttt agctccatca tcaaaggggc ttagaacatg ggaatttata gtggtagatg
     9061 ataaagaaaa gctaattaat ttatctcaat gtagaactaa aggtggtgga tttttcttaa
     9121 aaaatgcacc tttagctatt gtaattattg cagataaaga aaaaaatgat gtttggatag
     9181 aggatgcaag tatagctgct tcatacatac aacttcaagc tcatgaacta ggtttaggtt
     9241 cttgttggat acaagtaaga aatagaatgc atgatgataa tatagaagct gataagtaca
     9301 ttagagaaga attaaaagta cctagcaagt acagtgtaga atgtataatt tctataggat
     9361 atcctgatga agaaaagaaa gcatacggtg actctgattt agactataaa aaggttcatt
     9421 ttaacaactt ttagtatata atatgttgta ttaagacatt atattttttt ctattgttaa
     9481 tatatactta aaattgtaaa aatatatctg aattttacta acttatctag gggttatgta
     9541 caaggatttt aaagataaat atagaaatta atgtttataa tcgatacata acttgagtaa
     9601 caaaatttaa ggaggttaaa gtatgggtat atttaaaaca aaaatggatg aggactggaa
     9661 agtaaactac attaaagagt ttaatgaaat gagagattct tatgagagta aacttcaaaa
     9721 aaaacagttt gaggtagata gtttgaaatc agaattggat agactaagaa gctataaaaa
     9781 tagccttaag ccaaaagaaa aacaaattac tgatgatgat ataaataata taaagagttt
     9841 aagaagagat ggcttaagct ataaagaaat ttcaaatcaa acaagttgga gcaaagcaac
     9901 tgtaagtagg gtattaaatg gactttacga ttagcatata catggggtga tttaaattgg
     9961 gatgaagtat agttacaaaa aatgcataat agattctatt ttattgatgt ttatagttca
    10021 aatattaagg atgattttga attatgtact tctaagtcaa tttgaattta ctcttgaaaa
    10081 ttttaatatt ataaacttaa tttcttttac attagttggt ttatcgttaa ttttattttt
    10141 aaaagataat tctttgtata acaaggttag aaatagaaaa atcacagaag cttttgaaga
    10201 aaataaaaac aatatactta ttgaaaagtg taagctgata ctttttgttg tggttttatc
    10261 tttagcaata attgtaactt attgtactaa gggatatgta ctttttaatg taactatgat
    10321 gactttgtct gtattgatag tcccaatatt tgaagagtta ttttttagag aatatatatg
    10381 gaactatcta agtaatttta taaagtcaaa gagtaaaatt atctgtataa catctatact
    10441 atctggaatt tataatatag gatacataga tgttataaga aattatgtaa tattgtataa
    10501 caattcaagc tacacctttg aagttattat ttcaaaaatt atgataggta ctgtttttgg
    10561 tattgtactt ggattagtta agtataggtt tagagatgta gggttttgta tattattgag
    10621 gagcttattt gctatattta ttaggtagat agtataatcg gtttataagg ttgttttaaa
    10681 tttaatttta aatcaacctt attttatttg tgttttataa agcacttata tattaataac
    10741 taataaattt aataaaaatt atttgaatat ttttaaaata tataaatatg tattgacata
    10801 taaatattat gaattacaat ttatataaac taataaaaat taaataatat taatcaactt
    10861 attgaatgga ggaataaaaa tgaaatttgt gactttttgt agtagcaatg aagaaaaaat
    10921 aggtgtattt aattcagaaa caaatagtat atatgaaatt aatagtttag gattaagtaa
    10981 attatatact gatatgaatg attttattga aaacgtatct acaggagatt tagaaaaaat
    11041 aaaaaacaat tcatttgaaa acgcaaagtg ttataagtta gaagaagtta aattatgttc
    11101 cccaattgta agacctaaaa aagatattat atgtttaggt ctaaactata aagaccatgt
    11161 caatgaaatc ccagatggag ttataaaaaa cgtagttatg ccagattatc caatttattt
    11221 ttctaagaga gcagacaaaa taattggagt ggatgataag ataagcttac atggagattt
    11281 ggtagagaag ttggactatg aatcagaact tgcagtaatc ataggtaaag aaggtataaa
    11341 tatatcaaaa gaagatgctt atgaatatat atttggatat acaatagtaa atgatataag
    11401 tgaaagagca cttcaagata aacatgttca atggtttaga ggaaaaagct tagacacaca
    11461 tacatctatg ggaccttgta tagtacataa agaagaattt gaacatcctt taaaattaga
    11521 tataagtagt gtagtaaatg gagaagtaag acaagattct aatacagagt actttatatt
    11581 tgatatacct actataataa atgatttatc aagaggaatg actctaaagc caggagatat
    11641 aatttcaact ggaactccag caggggttgc tatggggatg aatcctcaag tatatttaaa
    11701 gcatggcgat atagttgaat gtaaagtcga aggaatagga gttttaaaaa atatagttga
    11761 ttaatggata aatatgccat ataattttat tagtacgaat aatttaatta atataggatt
    11821 aatcaaactt atgattaatt tattatagag agggatgagt atatggcaag agaactagaa
    11881 ttaaagtatg gctgtaatcc aaatcaaaaa ccatcaaaga tttatatgaa gaatggagaa
    11941 cttcctatag aggtattaaa tggaaaacct ggatacataa attttttaga tgcatttaat
    12001 agttggcaac ttgtgaagga attaaaagaa gctacaggtc ttccagcagc aacttcattt
    12061 aaacatgtaa gtccagcagg agcagcagta ggggtacctt tatcagatac tttaaagcaa
    12121 atatattttg ttgatgattt agagctttct ccattagctt gtgcttatgc aatggcaaga
    12181 ggagcagata gaatgtcttc ttatggcgat tttatagcac tttcagatgt atgtgataag
    12241 gagactgcaa ctattatagc aagagaggtt tctgatggta taatagctcc aggatataca
    12301 gatgaagccc ttgaaatatt aaaaggaaag cgtaaaggta actataatat tgtaaaaata
    12361 gatgaaaatt atactcctga acctattgaa acaaaggatg tttatggaat tacttttgaa
    12421 caaggtagaa atgaaatatt aataaatgaa gacctattaa aagatattcc aactgataat
    12481 aaaattttta cagatagtgc aaaacgtgat ttaattatag ctcttattac attaaaatat
    12541 acacaatcaa attctgtttg ttatgctaaa gatggacaag taataggggt aggtgcaggt
    12601 caacaatcac gtattcattg tactagactt gcaggtaaca aagctgatac ttggtatctt
    12661 cgtcaacatc ctaaagtatt aaacttaaaa tttaaaaagg atataggtcg tccagataga
    12721 gataacacta ttgatgtata tctttctgat gattatatgg atgtgcttgc tgatggcata
    12781 tggcaaaact tttttgaaga aaaaccagag cctctaactg gagaaggaaa aagagcatgg
    12841 cttaaaactt taacaggagt agcacttggt tcagatgcat ttttcccatt tggagataat
    12901 atagaacgtg caaaaagaag tggggtaagt tttatagcac aaccaggtgg ttctattcgt
    12961 gatgataatg ttatattaac ttgtaataag tataacatag tcatggcatt tactaaaaat
    13021 agattattcc atcattaaaa tactgaaagt ataaagataa tatagattaa gtaaaaatct
    13081 acaacaagtt ttgttgtaga tttttttatt tgctgtataa ttttaaatag aactttattt
    13141 ttagatattc aatttggagg ttgatatggc tttaaatata agaaactata gcctattatg
    13201 taatcaagga acagctaaat ttaatgaaga tgtagtcggt ataaatccat ttggggcatg
    13261 ggttttagat ggtgctacag gacttaatgg aaaaaattta gtgtcaactg aaagtgacgc
    13321 aaggtggtat gttcagtggt ggaataggta tttatataaa aatataaata aagaagaatc
    13381 attaaagagt attattaata ctggaataat agaagtaaaa aaagagtatg aactaagatt
    13441 aaatgggttt aaggttgaaa aattagattt accatctagt tctatagttg ttgtaaaatt
    13501 tcatgaaaat aaagtagagt attttttatt aggagattgt gctttgttta ttaaaaatgg
    13561 agattccaaa gttataaaag ataggagtat ttgtaaattt gataatactg tatttgatga
    13621 aatgagtaaa ctttctaact tggaagagat ggcttttgat gagattagaa ctagtgttat
    13681 ggatacaata gtaagcaata gattgaagaa aaatacaaaa gagggctatt ggatattgga
    13741 ttttgatgag gaagctgtgg aaaattctat atatggatac attgaaataa aaaaagattt
    13801 tcaattgatg ctaacgagtg atggttttac aagtgcatgt gatagatata atctaataaa
    13861 agaagaagaa ttgatacgta tagcagaaaa atttggtata ggatatatac ataataaagt
    13921 aagggatttt gaagataatg actataaagc ggttaaagtg ccaagattta aagtaaaaga
    13981 tgattcatct tgtttatatt tagatatata taatgattag actgtataaa actatttaat
    14041 tttagaaagg aggcaagtga aaagtgaaaa ttcttcatat aataacacaa aaaccaaata
    14101 gtacaggtag tggtatatat ttgtctggta tgataaaagg gttcgaaaaa atcggtcata
    14161 agcaagctgt aattgcaggt atagatgtaa atgatgatgt aaattgtttt ccaagtgaag
    14221 taagttttta tccagtaaag tataattgtg gggagttaaa ttttcctgtt gtaggtatga
    14281 gtgattctat gccatatgaa agtacaagat ataaagattt aaatatagac atgataaata
    14341 gattgaaata tcaatttaaa gtaaatatag ataaggctat gaatgatttt aaaccagaac
    14401 ttataatatg tcatcatttg tacctcttaa ctgcatttgt tagggaaatg gtaaaagata
    14461 taaaggttat gtctatttgt catggaactt gtttaagaca gttaaatacc attgatttag
    14521 agaaagaata cataatagca aatataagga aattagattt aatatttgct cttcatgaaa
    14581 atcagaaata tgatattata aagacttttg gagtaagtga aagtaaagta gttgtaattg
    14641 gtagtggtta taatgatgat atattttata ataaaaatta taaaataaag gatgataaaa
    14701 taaaaatagt atttgcaggt aagatatgta aatcaaaggg actgattcca tttataaaag
    14761 ctatatctaa attaaaatat agtaaagatt taatagaagt caattttgca ggtactggaa
    14821 gcgatatcga atcatataat gagatagtta aactggcaag taagtctcca tttaaaatga
    14881 atttcctagg aaagttagaa cagagagatt tagctgagct attcaacagg tcacaaatat
    14941 ttgtgttacc atcattttat gagggattac cagttgtagt tttagaagct ttatcttgtg
    15001 gcacagatgt aatcactact gatattcttg gtgttaaaga gtggattggt agtgagatta
    15061 ataattctgg aaagatagaa tatgtttctc taccttttat ggagaaagaa ggtattccaa
    15121 aagatgaaga gttatatgat tttgaaaata atttgtataa tgcaatagat tctaagatac
    15181 aatctttatt gaataactca aataagaaaa catctgtaga tatgtcaaaa aaaacgtggg
    15241 atggcttagc atatagaata aatgaagtta ttttaatgga tgaattgtgt ttagtctaaa
    15301 attatttaaa ttataaaaaa gtgtaactat ttttacacta tttttaaatg attttatatt
    15361 atactaatac taaatatatt tgttttaggg aggtaattta tgaggattag taaaaaggta
    15421 ttggcgttag gtatttcagc attactgtta agtgttagtt ttccaacatc aataaacgca
    15481 ctagataaga ttgaaaatat tcaaggagta gataaatatg aaacagctgg gcttatttca
    15541 gataagcaag attttacaac agcagttctt atcaatgcag actctacaat ggtagatggg
    15601 attgctgcaa gtggtcttgc aggagtaaat aatgcagcta ttttattaac taataaggat
    15661 gatataccag aagcaacact tcaaagactg aatagagtta ctaagatata tgtaataggt
    15721 ggagaaaatt ctataagtaa agatgtagaa aaaatgttac ttatgagaag aatgcaagtt
    15781 ataagaattg atggtgtaga tagagtagat acaagttata aaattgcagg tgaaatagaa
    15841 aaaattaaaa acagtgataa gatgttttta gtaaatggat ttaaggatga agctgatgca
    15901 gtaagtgttg catctgttgc ttatagagat ggagctccta taatattgac aaaagatata
    15961 ccttcagcag aagaagacac agacttagac ccatggtttg gagtttctcc tgttccagta
    16021 tatgctattg gaggagagtc tacattaagt gattacatag tgagcagata tagagcaact
    16081 agaattggtg gtgttgatag atatcaaact aataaaaatg ttattgaaaa gttctataat
    16141 ggagcaaaag agttctatat aacaagtgga gatgatttag tttatgcttt agttgcatca
    16201 ccacttgcaa aaaatgctcc tgttgtttta gtttcaaata aaagtgataa gagtatatta
    16261 agtggagcta gtaaagtaac agcaataggt ataagtgata agagtattat agagcaatgt
    16321 ttggatgctg taaagaagta atggagtgtt attagtaaaa tgaatatata cattgaaaat
    16381 tagtagattg ttcattttat aatggtataa aatatatggg aagaggctat caaatggaga
    16441 taagcctctt tttcattgtt aaaattatga aaagatactt tattttatat aaaaaagtat
    16501 cttatgaact aaatgtctat tttgagacac tatctacttt tcttatatta tattattttt
    16561 tatatggaat aaatttcata agtattatct tcctttaatt tttctaacca aaccatctct
    16621 aaaatatcta gttcttctaa atagtctttc tctgttttgt tatcatcatg ttttataagt
    16681 tctaaaactt caaatgtaaa tgctttttca ccatattttt tccattcatt atttaattct
    16741 tttatcatac atgagccagc accaagctga aatttgagag agttaaattt gctttttatg
    16801 tcattacttt ttccaaggta aatcttttta gtaatatcat tttttattat gaatacacct
    16861 gtgtcaaatt tcatttcttt gtataattgt tttaattcac gttttctatc catgatttta
    16921 gatacctctc tttataattg atatgtaata tgtaagtgta aaaatatatt acatatcaat
    16981 tataaagaga ttaattttat atgtaaatag tttttataaa tttaattatg aattagtcat
    17041 caataaacaa gaaatttagc tgtaaaaatc cattataaag gctattataa attttaatat
    17101 gctaaaaata taaaaagaat agttgacagt gtagaaaata tggaataaac taaaagtgta
    17161 atagtaatat gaagttatat attacattga aaggtgtgaa tgattattat gaataaaaaa
    17221 atagaattaa tagggaattt tgcaagtgat tggattaggt atagtgatta tgaatataaa
    17281 attactgaag aagatgaatt atatatagtt ccaacagaag atgctgtgtt taccatgtat
    17341 aacccatttg atgtagcaga tgatataata gtagatataa ttcgcatagg acaagaggca
    17401 ttacaagata tatcaaaaga gacaaaagaa atgaaactaa agaaagaagt acttgaattt
    17461 gtaaaaaagt atggattatt gggtttaata tattcaagtg tatataatag agatatagtt
    17521 ggagaagaaa gagtactgat gattgaaaag aattatatta caaaagagaa tatattgagt
    17581 acagatgaat atgtaaacat gtttatacca tttgcaagtg atgaagatgt gtattttaaa
    17641 aagtatagaa ggggtataga tgtatcaaag agagaagaat ctccaaagtt ttttggaaag
    17701 agaccattga ttttagattt agtattttca aagttctaca ctgaacaact agattggatt
    17761 gtaagttttg ctaaagatat gtgtaagcat tttaatcaaa tttgtgtata taaaaataca
    17821 tctaatctat taactgaaag tgttactatt atgtctggag ggtttaatcc tcaaaagata
    17881 ggattttcta taagccaatt agataaacca attattgcat gggagtttga ttctttgaaa
    17941 acagctattg agactatcta tgcctttgca attacaagtg aaccttcttc tttaaataaa
    18001 tgcaagtact gtggtaaaat ttatattcct acaaattcta aatctcaata ctgttcacct
    18061 tcttgtagaa attgctcaaa tgtaaagaaa agtagaagta gagccaaaaa agataaataa
    18121 aattaataaa tatatcattg tttagatttt agtaaataac tactgaatta aaagttgtta
    18181 tagaaaatta tatatctaaa tgatggtatt tttttgttga gaaaattgaa aagtttaatt
    18241 gagatagtaa ttttgagttg acaaaaacca cttttaacac tactattata agtggttggt
    18301 aaaataatat acattaattt aagtatagca taaaaaacaa aaaaagtcaa tggaaaaaat
    18361 aaaaaaggag aatttaaaaa tgatatcacc tattattttg agttctataa atcagaattt
    18421 aaaggaaata gaaagaaatg aactgcttga aactaatata gaatctggag attatggtct
    18481 agctctttct gaatctgatg taaaagatat aataaattcg agagataata ctttaaaggg
    18541 gtatggaaga atagaattag atataaaagt tacaaaacag ttaatagaaa atatatatac
    18601 atcacaatat acaaatgtgg acaattattt agaggctatt aatgatatgc aagaaatttt
    18661 ttattattta aaaaatgaaa ctgatgacaa gatatgtgat gatgagatta tagaaatact
    18721 gggtgaattt tatgaaaaat tttcaggcaa tatggacaat gtaagaggag aagcagacga
    18781 atttgcaaag aaatttaaat ttggagaagt ttaatatatg ataggagaga ttttgtatgt
    18841 taaataattt aagtaatatt aatataaacg aaaataattt aataaagaac caatattcca
    18901 tatctctact taaggaatgt ctaaattgta aagtgataga tgaaagagaa gtatataata
    18961 tacaacaaga agtatctcta atacttatgg acttgattaa aaaatataca aatggtcaaa
    19021 gcacatcagt aaaaacagaa gttgccgaaa aactgttgat ttcaatatgg tatgctattg
    19081 atgcatatat aaataagctt ggagatatag aaaaaagagt tgtggagttg actgctaaga
    19141 atgttaaaaa agtgtacctt ggaggcattg aaatattaga ggaagagtta gttaggctaa
    19201 aagattttta taaactaatg atgagtagaa aattggatac taattcaata gcatataatg
    19261 ataccttgat ggagttatca agtttcttta aaagttatat tgtaaaattt gaagctcagg
    19321 acgttccagt aagtatagat tatccattgg cactagatga tatggatgtt aagggtattt
    19381 attatgtgaa gaattatatt gagagtatag atatagaaaa tagattttgt aacctattta
    19441 agaaaaaaga tagagaaaaa ttattttatg actatgggat gacttataaa atagattgtg
    19501 atgttatact tgtaaattta tttgaactta ttatgaataa ttgtattttt tctactattt
    19561 taggaaatga agtgactaat ttagaaattt caaaatatga gtatgaattt ttagaaaaac
    19621 aatttaaaaa tatgtacaat aatattactg aagataaagt tatagactct gaagaaagta
    19681 atataattga attgattgaa gtagatgata gttttaacac tgaagtagat agtaatttgg
    19741 attataatga ttttgaagaa attaacagag aaattagaat aaataaaaaa ataactttac
    19801 tacttatgga agcaattgaa gtattaataa aaagattaag catagaagat gaagatgtaa
    19861 taagatatat taaaaaatat gaaaagatat ttattgaatc tgtgctaagc tcaataaaaa
    19921 gtaacacttt taaaagtatg gtaactgtga gtaaaaataa aaaggaacac ttagaagatt
    19981 atattgttga tgatgaaagt aaattggatg atgaatcgtt tagagagata ttcaatgaga
    20041 tattagatag tacatctata attgaaaaaa taagaataat aaaggaaaat atcaatgcta
    20101 aaaaagactt tatcgatatt cttgaatctg aatgtttatt tggagaagag tatttaatgt
    20161 tgtttgcatc attaagtgaa ttagaattgg caatattggg tagtgtagta ttttatgaag
    20221 atattagaat gagagaaatt aatatattag aatttatgtt aaatgagaaa actgaaacta
    20281 ctttatggaa gatagagtac attaaattta tgaagaggca aagtgaagat aagatatact
    20341 ccatagaaga gcatatgaat aaaattaatt aacaaaaaat tgtgaataaa tagaatgtta
    20401 gtatataata taatctgtaa agcatatcaa aaatacatat atttggagga aaattatgaa
    20461 agagtatatc ataaataatg ttgaagaaat aagagaagaa ttaattgatt tatctaagaa
    20521 aatatgggaa aatccagaat tagcctttga agaaaagtat gcaagtagca ttcaaaaaga
    20581 atacctaaag tcaaaaggat ttaaaattga agaagtagaa aatttaccta ctggatttat
    20641 agcaagtttt ggagagggta aacctgtgat tggcatactt ggagaatatg atgctttacc
    20701 agagctatca caatgtgtaa gtgcagaaag aaagccattg gtagaaggaa aagctggaca
    20761 tggatgtggg cacaacctgt tgggtgtagc aggtgtagga gcagttgttt ctataaaaaa
    20821 attaatagaa gaaaataaat ttaatggaac aataaaatat tttggttgtc ctgctgaaga
    20881 agaaggtgga ggaaagacag ttatgtgtat aaatggctgt tttgatgatg tagattgtgc
    20941 atttacatgg catccttttg atataaatgc accttggaga ggtggaagtc tggcaaactt
    21001 atctgtaaaa tttaaattta aagggataac agcccatgca gctcaagctc ctcataatgg
    21061 tagaagcgca cttgatgctg ttgaaattat gaatgttgga gctaattatt tgagagaaca
    21121 tgttattgac tctataagaa tgcactatgt tataactaat ggtggtggaa gacctaatgt
    21181 agttcctgga tttgctgaaa gttggtactt tattagaggt aaaaaagcaa aggatgcaga
    21241 acacgttctt gatagattaa taaaagtagc tcaaggagca gcaatgatga cagaaactga
    21301 aatggagtat aaggttacag atggaatata tgactatata ccaaaccaat gtttgactga
    21361 tttagtttat gacaatatgg tttttgttgg ttgccctaaa aatactcctg aagaagaaga
    21421 atttgcaaaa aagttgtgtg atactcttac tagagaagaa agattaggtg tagcaacatc
    21481 attacaaaat gataaatcta ttgtagaaag ctatatacac aaggaaatag ttgacggtga
    21541 caaagataaa ggactagctg gttctactga tgttggagat gtaagttatg taataccagt
    21601 ggctcaattt gcaatggcag cttggcctgt tggaattgca agtcatacat ggcagtcatg
    21661 ttcatcagca ggttcaaata taggattttc tgctatgata aattcagcta aagtactggc
    21721 ttgtagtgct tatgatgtat ttatggatac taaaattatt gatgaagcaa aaattgaatt
    21781 tgataaatca ttagatggac aaaaatttaa accattggta taattttgct aataaaatat
    21841 ttctgggggg aatagctatg agagaaaaag ttgaaaaagt gcttgaggaa aagataaaac
    21901 cagtattaca aagagatggt ggagatgtag agcttataga tgtaaatgaa aatggtgtgg
    21961 ttttagttag actacaaggg gcatgtagtg ggtgtccagg agtgactatg acaatcaaag
    22021 ctattattga aaatgttttg gtgagtgaag ttccaggagt aactcaagta ttaggtgttt
    22081 aatagttagc gtttattaaa tgtatgttat acataagtat ttaataaaga agtaaaaaaa
    22141 atagtgaagc aatatatatg aaaaagtatg agaaagataa taaaacatta tagaaataat
    22201 gaaatatttc atatgtatat gaagaaataa gaaaaaatag tgaagcaata tatatatgaa
    22261 aaagtatgag aaagataata aaacatttat agaaataatg gaatatttca tatatacata
    22321 tgaagaaata gtaaaacaat atatatatga aaaagtgtga gaaaataata aaatactata
    22381 gaaacaatta aatattctat ataggtatta agaaacatga aagaaataat ggagtattat
    22441 aaataaatat gtaaaagtgt gaaagaagga tgtagataaa tttgtcttat acaaatttac
    22501 ctacagtatt tcttacacac tttttatttt actatccagc cataccaata aacataccta
    22561 taaaatatgg aactaaccat atagtccata caactatact aaacttatga aagaattttt
    22621 tcttttcctc atcatctttg tataggacaa aagtagccca acttgcatga aaaagcataa
    22681 gcacaattgc aagaagacct gtaatactat gaaggttttg tgataaagca gattttactt
    22741 caaaagtatg gctgttggct atgttactca ttgtaaatgt tcctaaagta tcaaatataa
    22801 aaccaagcca aaatataatt acatgtttct tttttaaaat ttttgccttt ctttctccaa
    22861 atacacctat agtgtagaaa attaaagctg atgttataaa tactattgca agtattaatt
    22921 tataattcat aattatctct cctttacttt tgccaatata tttctaagat tttttactaa
    22981 gtcactcaat tcgttttcat cacaattttt aaaaatatca tcaaaacttt cttgcatttt
    23041 aattttaaaa tttgtggcaa attcaaatcc tgttgttgta aacttaacgt atgtatttct
    23101 tttatcatta gatttcttga atttttctat atatccaatc tgttctaatc tgctgattat
    23161 gcctgaaacc gtacctttag ctaaagacat ttcatcacat agttgtgata ttgtaagttc
    23221 ttgattatga gctatcagtt ttataactat aatctgttgg tgtgttaatc cattttcttt
    23281 aaaattttct tctactgtgt acatagtttt agaataaagt tcttttaaga gcatggctat
    23341 tctaaaacag tcataattac ttttcaataa aatcacctct taaatggttt gcatacaaac
    23401 taatataata tacttttctt atatagtcaa cctaaaattt tataatttta tagaaaataa
    23461 tgaagaatag aatataaaaa ttttatttta ggtataaata aaataatttg atgaaatttt
    23521 aacaattttt aaaaagtttg tttacacagt taataaatga tgctaaaatt aactcataga
    23581 taaatataga aaatttaatt ttgtttaatg ataatggaac cacgaaggtt ttaacgttac
    23641 tttacgtttg cttttatgtg gtttttttta ttgcaacaaa ggggggttgg ggtttgttaa
    23701 aggatatact gaaaaagttg ttgcagttta ttttagtaat gtttttatta tcttttattg
    23761 ttttttacat ggcaagactt gctccaggag acccattaat ctcttactat ggggatggag
    23821 tagaaagaat gagtacacaa gaaaaagaaa atgctatgaa aaaacttggt ttggatgaac
    23881 caatatacag tcaatatata aaatggattt caaatgcatc aaaaggggaa tttggaattt
    23941 catttaaata taaacaaaat gttacttctg ttataaatga tgtctatata aacactataa
    24001 tattaggtgg ttcaggatat atacttacct ttgtgctagc cttattgtta ggaatatttt
    24061 gtacattaca tgaagataag ctcattgata gaatcatatg caaattagga acaataacca
    24121 actgtattcc atcattttgg gttgccttag tactcatact tatatttagt ataaacttaa
    24181 gtatacttcc aagtagtggt gcttattcaa tgggagaaga gtccagtata ttaagtagga
    24241 tatcacatct aatcttacct cttacagtac ttatattaag ccatctatgg tattacacat
    24301 atatgataag aaataaatta ctagaggaaa taagagaaga ttatgtgctt ttatgtaaag
    24361 caaaaggttt aaataataga actattgttt ttaagcattg cctgagaaat ataatgccat
    24421 catatattag tataatggcc atttcgatac ctcatatact aggaggaact tatgtagttg
    24481 aaaaagtttt ttcttatcct gggttaggaa cactttgttt tgaaagtgca aagtatcatg
    24541 attataatat gttattagtt ttatgcttaa taacaggggc tttagtagta tttgggaata
    24601 tgttagctca aattataaac aataaaatag accctagaat gaaatatgat agaggtgata
    24661 ctaatgaagc cacaatatag tgattttgaa attgtaggag aaaattatat tttagtagca
    24721 gaagatgaac atatagaaac aaagaaaacc ttatctaaaa aaattaaaga attaccatat
    24781 atatcaatta ttattttatc aatcatagtc attggaagtg tattctcatc ttttataatg
    24841 acacatgaac caacatacat ggatttagca agttctaatt tagctccaaa taaaactttt
    24901 ttatttggaa cagactcaat gggtagagat atatattcta tgatatggta tggaggaaaa
    24961 atatctttat ttataggact attttccact gtaatatcaa ctgttatagg aattgtttat
    25021 ggtagtataa gtggttcagc atctgaactt gtagatgatg caatgatgag gtttacagaa
    25081 atcatactta gtataccttc aatattaatt ataatatttg tacaagctat acttggaaat
    25141 tcaaatccag tatctatgtc catagtaata gggataacaa gttggatgaa tatatctaag
    25201 atagtgagaa cagaagttag acaaataaaa aatagcgaat acatactagc agctaagagc
    25261 atgggaggag gattcttcta tgtattaaag caacatttac ttccaaattt tgtggcatca
    25321 ataatgttca tggttgtaac aaacataggc gcagctattg gtactgaatc gacacttagc
    25381 tttttaggaa ttggtttacc aatagaaatt gtttcttggg gaagtatgtt atctttgtca
    25441 gaggaagcat tactttcaaa tagatggtgg attatactga ttccgggtat atttttggtt
    25501 accacattgg tgtgtataac aaatataggt aattatataa gaaagaataa taataaaaaa
    25561 tctagtaatt tataaatcag catttgagta ttaaataagc aaatactgag gtatttgaaa
    25621 tatctattta aataaatggg gtcaaagctt tgaaaaatat tttataaaaa gcaaaagggg
    25681 gagcatcatg aaattaaaga agttaaaagt tttaagttta gtaatgatac ttagtctaat
    25741 ggcaggttgt tctagtggag gagacaaaga taagaaggca gatacgccta aagatggaaa
    25801 ggtgcttgtt tatggaagta atgactatac aagtataaat cctgcactat atgaacatgg
    25861 agaaataaat tcgttaatat ttaatggatt aacagctcat gatgaaaata ataaggtggt
    25921 tccttgtcta gcaaaggact ggaaatttga tgaggcaaca aatacatata cttttaattt
    25981 aagagatgat gttaagtggc atgatggaga aaaatttaca gcaaatgatg ttaagtttac
    26041 aatagaaact ataatgaatc cagataatgc ttctgagata gcatcaaatt atgaagatat
    26101 aacaaaaatt gatgtggtta atgataatac tataaaaatt actttaaaag ctccaaatac
    26161 agcaatgctt gattatttaa cagtaggagt attaccaaaa catgctttgg aaggtaagga
    26221 tatagctact gatgaattta atcaaaaacc aataggtact ggaccattta aacttgaaaa
    26281 atgggacaaa ggtcaaagta taacacttgt taagaatagt gattattttg taaaagaacc
    26341 aggattagat aaagtagtct ttaagattgt tccagatgat aaggctaagg caatgcaatt
    26401 aaaatcagga gaattagacc tagctcaaat aactcctaaa gatatgtcta actttgaaaa
    26461 agacgaaaag aattttaaag taaatataat gaaaacagcc gactatagag gtatattata
    26521 caattttaat tctaaattct ttaaagataa aaaagctaaa ggattaccaa atgctttaag
    26581 ctatgcaata gatagaaaag caatagttga cagtgtatta ttaggacatg gtgtaccagc
    26641 atattcacct ttacaaatgg gaccatataa taatcctgat atagaaaagt ttgaatataa
    26701 tccagaaaaa gctaaacaag aaattgaaaa gctaggttgg aaattaggtt ctgatggaat
    26761 ctatgaaaaa gaaggtacta agttagcttt cgagataaca gcaggtgaga gtgaccaagt
    26821 tagagttgat atggctaaaa tatgtgcaca acagttaaaa gaaattggtg ttgatgctaa
    26881 agctgttgtt gtaactgaaa cagattgggc taatcaagat gctcatttaa taggttgggg
    26941 aagtccattt gacccagatg accatacata taaagtattt ggaacagata aaggtgcaaa
    27001 ttacagtgct tactctaatc ctactataga taaaatactt caaaaagcaa gagaaacaga
    27061 agataaagat gaaaaattaa agttatataa acaattccaa gtagaaatga ctaaggatat
    27121 gccttataca tttattgctt atatagatgc aatatatgtt ggaaaaccaa acataaaagg
    27181 attaacacct gatacagttt taggtcatca tggtgtaggt atattctgga acatagctga
    27241 ctggacaatt gaataatact gaaattaatt agaaacctta gggataaaaa tatatcccta
    27301 aggtttgaat agcatagggg ttgatggttt ttggaacatt tattggaggt taataatcta
    27361 tctgtaagtt ttaaagtaga agaaggagaa gttcaggctg taagaaatgt atcttttaat
    27421 ctaaaaaaag gtgagacatt ggctatagtt ggagaatctg gttgtgggaa atctgtactg
    27481 tgtaagagtt tgatgaggat actcccatac aatggatata ttaaaaatgg agaggtttta
    27541 cttaaatcaa gtgatttggt taagaagtct gaaaaagaga tggaagatat aagaggaaag
    27601 aatatatcaa tgatatttca agaccctatg acatctctca atccaactat atcaatagga
    27661 aagcaaattg cagaagctgt aatcattcat caaggtataa gtaaaagtga ggcaaaaaag
    27721 agagccatag agcttattga attggttgga attgataatc ctgagaaaag atttaaacaa
    27781 tttccacatc atttttcagg tggaatgaga caacgtatag taatagctat agcacttgct
    27841 tgtaatccag atgtattgat tgctgatgaa cctacaactg ctttagatgt aactatacaa
    27901 gctcaaataa ttgatttaat aaaggattta caacataaaa taggtttgtc aataatattt
    27961 ataactcatg atttaggagt agttgcaact atagctgata gaatagcagt tatgtatgca
    28021 ggaaagattg tagaaatagg aactgtagag gatatatttt atgaccctag acatccatat
    28081 acttgggggt tgttgggttc attacctact ttagattcgc aggatgacta tttatataat
    28141 atacctggaa tgcctccaaa tttattgaac ccaccaaaag gagatgcttt tgcaataagg
    28201 aataaaaatg cacttaagat agattatgaa aaagagccac caatgtttaa aattaatgat
    28261 acacatagtg cagcaacttg gttattgcac ccagatgcac ctgaagtaga tgtaccagtt
    28321 agagtaaatt gtggaagggt gatttctaat gaatagagaa aaaatactgg aaataaaaaa
    28381 cttaaagcaa tattttcatt tggacaaaag tactactgta aaagcagttg atgatataag
    28441 ttttgatata tataagggtg agatatttgg attggtagga gagtcgggtt caggaaaatc
    28501 tacaactggt aaaactataa taagactaca tgaatctact ggtggagaag taatttacaa
    28561 aggaaattgc atatcagata aaaaaacgta caaatttata aaaaaagatg taaacaaaag
    28621 tatgcagatt atttttcaag attctacttc atcattaaat ccacgtatga caattgcaga
    28681 tataatttca gagccactaa aaattcaagg tatctgtaaa aataaaacag atagaatgaa
    28741 taaagtatat gagatgctaa agctagtagg acttgataga agttatgcaa ataagtatcc
    28801 atctgatttt tcaggtggac aaagacagcg tattggcata gcacgagctc tttcagtaga
    28861 cccagaattt ataatagctg atgagcctat agcttctttg gatgtgtcta tacaagcaca
    28921 aatagtaaat ttatttaaaa aattgcaaca agaaaagaat ttaacttgtt tatttatagc
    28981 tcatgattta tctatggtga gacatattag tgaccgtata ggagttatgt ataatggaaa
    29041 attagtagaa ttggcagatt caaatgaatt gtataataat cctattcatc catatacaaa
    29101 atcactactt tctgcaattc ctgttcctga ccctagatat gctaagtcaa gaaatagaat
    29161 agagtataat tctaatggat atgattgttc aaatgaaaag tcattaagtt ggattgatgt
    29221 ttcagatgga cattttgtat attcttctaa atcagaaata aataaatatc aacaaaattt
    29281 aaaagttgtt tagtataaaa atacttgaac aggtatttat ttgaaataca aactaaaacc
    29341 ctatttttgg agaaatttta aaactactcc aaaatagggt tttttatttc tacttttcaa
    29401 atataataaa ttcaaatata ataaaattaa aaacaagtaa agtatgttgt taagaaagta
    29461 ctataaaatt aaaaatagta atgtagaaaa aatgagcaat aatcttattt tttctacaat
    29521 aattttctat aatttaaagt aaggaaagtt tgataaatta taaccttagt taaagaataa
    29581 gagtttatta aaaaataaag tgtgtatagg ggttttagtt aataaaatac tataatgtag
    29641 gggagcttgt aatgatatat aaaaaagata aagtaatgaa agttttagaa tcatcatata
    29701 gggaaaatga aaaagggatt acagctaacc aattatcaga aaagacagga attgcaagaa
    29761 acaatataag tacatattta aaccaattat tcaatgaggg tatggttacg aagataaaag
    29821 gaagacctgt gtattatatc cctgcaaatc ttaaccttaa caagaatgaa ttgcttgata
    29881 cacaaagtga gttgcttggc ataaaaaaag gaacaaaagt agaaaacaaa ataaaaaaag
    29941 atagttttga aacactaata ggtaaagaac atagtttaag acctataata gaaaaatgca
    30001 aggtcgcaat gctctatcct acaaatggac ttcatactat tatctatgga gaaacaggag
    30061 taggaaagag tatgattgct agatatatgt acgattattc tatagatagt ggaattagaa
    30121 aaaataaagc tccttttgta acatttaatt gtgctgatta tgctaataat gcacaattac
    30181 ttatgggaca tattttttgg gtagaacaag gagcttatac aggtgcagaa tcttccagaa
    30241 aaggtctttt ggaaattgca aatggaggga tactattttt agatgaaatt catagactac
    30301 cagcagaagg tcaagaaatg ttgtttactt ttatagataa gggaacattt aaaagactag
    30361 gagatgcaac gaaagaaaga gagtctaagg tattaataat atgtgctact acagaaaatc
    30421 cgacatcaac actattagat acattcaata gaagaatacc aatgaaaata gaaataccat
    30481 cactgagaga taggacaatg attgaaagaa tggaattagt caaaaatttt ttcaaggaag
    30541 aatcaaaaag tatttctatt tcaataaaag tacataaaga aataattaaa tcactattac
    30601 tttatgattg taaaaataat gtaggtcaac ttcaaaatga tataaaatta gctgttgcaa
    30661 atggatacct aagatataaa agagataata aagaaccagt ttatatagag aaaaaatatt
    30721 ttgataaatc tataaatgaa gtgagtgatg attatagaga gaagtctatt aaagcagatg
    30781 aagttataac acatggaata gaatattttg tatttacgtc attaggagaa gaagaagtta
    30841 ttaactacaa tgatataaat attattaatg cagtaaatac taatcttaat aaatctgtag
    30901 aaatgaatat agcagatgct tctctattta ataatgttaa gtttaaaagc atgtgtgaat
    30961 caataagaca aattattaaa gaagatgaag aaatagacat aagtgaatca atatttaagt
    31021 caatggcaat ttatataaaa agcgtattgg ataaaagtag ctctacaaac aacatagatt
    31081 tgaatcaaat tagaagaaat aacagaagtg aatttaaaac agcactaaaa atagttggaa
    31141 taattgaaaa tgaatttgat ttatttttat ctatagaaac tgtagcatat attacattat
    31201 tcatagtaca agctaaacaa gatgaacaaa ataaaatagt gaataacatt aatattatag
    31261 ttgctatgca tggagaaact acagcaagta gtatggtaaa agcagttggt gatattattg
    31321 gaaagtgcag tgctatttct ttcgatatga agttagataa aagctatgat gaagttattg
    31381 tagattttaa aaatttaatt aataatatag acaataaaga tgtattacta tttacagata
    31441 tgggttcatt aaactctttt gatgaaatta taaagaaaga aaaaaagtgt ggagtaagag
    31501 taattcctat ggtgacaaca ttaactgtgt tagaagcagt tcagaaggcc aatatgggat
    31561 tacctttaaa tgacgtatac aactctataa ctaacacgag aaagtactat tttggaacta
    31621 atgaaattca aaataaagaa aatctgtcta aaacaattat tatagcatca catgtttcag
    31681 aaggtgtaga taataaaaca agaaaaatat tagaagaaaa gatgagtagg tacttagatg
    31741 gaatagatat tatatctgtc ccatataaaa cagaaaaaga tttaagttta aatattacga
    31801 aacttaaaga aagtagtaat attgttgcag taatcaatga acaaagaatt aatattagag
    31861 gaattgacta tattagcaaa aaagatatag ataaggatga aaatatcaat aaattaaaaa
    31921 atattataaa gataagtata ggttatgatg atgtagttga aggtttaaag acatccttaa
    31981 aaagctctaa ttataatagg atatttaaag atataaaata tgtgtctgat gaattgtttt
    32041 tagtatttaa tatagaaaag aaatacgata aagtaattgg acttatgatg catttagctt
    32101 tcatggtaga tggattgatt ggaaatacta gagaaattga aaagcttgat aaagaaaaaa
    32161 cacttgatta tcacaagagc ctaagcaaaa taaaagatat agtatctcaa ttagataaaa
    32221 aatataatat agaaattaat gaaaaagagt gctatcaaat attattaata ttagaatatg
    32281 cagaaataat cgaaaaagat taccaatgag tataaaaact tatttggtaa ttttttttag
    32341 tctaaaataa tattaatatt agacacatat aaatatactt agacaaagta tctaagtttt
    32401 gatgataaaa atgattgaaa taacagtgtt ttaaagtgtc taaaaaaact ggcataatac
    32461 ttgcttatat tattaaatga gtaatataaa taattaaaat ttaaataaaa aggagtaaat
    32521 aatatgcaag ataaaatatt aagagataaa aaggcaaatg acccatgggc aagaatgact
    32581 acaagaaacg gatttagtgc agatgaaata atatcgtcat ttcaaaaagc tataagaaga
    32641 aatatggtgg aagaagcttg tgaatttgct tatgaactat atatatcatc accagaatta
    32701 gaagataagc tatggagaag gatacttaca atatcagttg aagatatagg aatgggggac
    32761 ccatcagctg taataatcat aaataattta aatcaagtaa gaaaggaata ttcatatgca
    32821 gatggagaca gacctttatt tttcatacat gcaataagat atctttgtgc atgtgagaaa
    32881 gatagatcaa gtgatttatt aaaaaatata attataaaag gatttgcaat gggtaaagtt
    32941 ccagaagtta tggacgtggc acttgacaag catacatata gaggattaga aatgggaagg
    33001 gattcattcc actttttaaa tgaagctagt atagtaatac cagaaaaaga agtagataat
    33061 gattataaag aaagatactt aaaaatatta gaaaaatata agcaagaaga agttatagat
    33121 acggctttca agtttaatca ttggcagtac taagaattag agtaaatatt aataagaatt
    33181 aaaataaaat aataagaatt aaagtaaaaa ctgataggaa ttagagtaag aattggctga
    33241 taaaaaatta gaaaataaaa gaggttagat attgtaggag ggtaattatg aatattttat
    33301 tagtatgtgc aaatggagct tcaacaggtg tacttgtgga aaagatgaaa agtttttgta
    33361 gtgagcatga aaagttaaaa actaaaacta taaatataga ggcaacatca tttgaaaatt
    33421 taaaatcata cattgaagct aatgataccg atgtagtact tgtagcacca caaattaggt
    33481 ttaaggaaga tgatgtagtt gaagcttgta agaattacaa aatagcagtt ggtttaatag
    33541 atactaagca ttatggtcgt atggatgctc cttctgttat gaagtcggca atcgaattat
    33601 ataaaaatag ataattgggg ggaataaaaa tggaagcact tcaaaataat ttaagaagat
    33661 ttcttcttcc aatagcacaa aagattgaaa aacaaaggca tcttcaagct ataaaagaag
    33721 gtatgataag cattacccca ataataattg ttggttcttt aagtatgtta tttatggcat
    33781 taaacaatat gttacctgaa ggaagtgcaa aaacattatt atctgaaaat atggatacat
    33841 tacttatccc taataaattt actatgagtt tattatctat atattcagca ttttttatag
    33901 ctcaggcact agctaaaaaa tataatctta atcatgtaga aataggtatg acagcagttg
    33961 ttgcacaact tgttgtatgt ggacaagtag tagatggtgt attagataca agttatttag
    34021 atgcacaagg tttatttgta agtatattag tagcactttt agtagttgat attactaagt
    34081 ttatgaatga taaaaatctc gtaattagat ttccaaaaga agtacctagt gtagtaaata
    34141 aaagttttag aaacttaact ccaatgatag tatgtataat gttatttaca gcaatagcag
    34201 caataactaa aaatgtctca ggtcaaccat taccagctat tataatgaat ttcttagcac
    34261 cagctataag cagtgtagat aatgtttttg cagtaactat aatactattt ataactcaat
    34321 tattatggtt ctttgggctt catggagcag caataacttc aagtatatgg atgccaatag
    34381 cagctacata tatggcagaa aatgcaacgt taatagcagc aggaggagac ccaaaatatg
    34441 tgtttacaat aggtttttac tatggtttct tgcaagtaac tggttcaggg ataactttgg
    34501 gattagtgta ccttatgtca agaagtaagt gtaagagttt taatagtatg ggaaaagttg
    34561 tgattttacc atcactattt ggaataaatg agccggtaat atttggaaca ccaatagtta
    34621 tgaacccata tatgtttgta ccatttgtat ttggacctgt attggttgga gcacttaatt
    34681 ttatggcatt aaaagtagga ttagtaggat tacctattgc agaaccacca ggctttttac
    34741 ctccaggggt tgcagcattt ttgatgacat tagattggaa ggcaatcgta ttagtatttg
    34801 caagtataat acttatgacc ttgatatatt atccattctt taagataatg gagaaggaag
    34861 aattaaataa aaatgcagaa ttagctacaa cattagatga tgatagcttt gatttttaac
    34921 aagtcattag aaggagaagg atatggtacc tgaaatggaa gaaaaagtat ttagtataat
    34981 atcagaagca ggagatgcta aaagtgatgt aatgatgtct cttaaggaaa taaaaaaagg
    35041 tgactacaat aaagcaaaac accttttaaa ttcagcctca gagaaaatac aaacagcatc
    35101 aaagcatcat ttagaattac tatcaaatgc tatgaatagt gaagatagtg ggactgattt
    35161 tttagttgtg cactctgaag accattattc aaatgcatta tttgctcatt ctttagtatc
    35221 tgaacttgta gatatatttg agatgatgga cccaagaatt aataagaatt aaatttcttg
    35281 taaatagtgc ttgaagtttg gctatagttt attaaatcaa tagatttaat aaatgaactc
    35341 ccttttactt taaagtacta gtatttataa atttatttat aaatacagta aatttttaaa
    35401 tagaaaagga gatattatta tggaaaaatt ttcagtagta atagctggag gaggaagtac
    35461 atatacccca gaaatcatat taatgttgct agataactta gataggttac cattaagagc
    35521 aatcaaatta tatgataatg atgaagaaag acaaaataag gtagctaaag cttgtgaaat
    35581 actaataaag gaaaaggacc ctaatataga gtatttagca acaacatgcc ctaaagaggc
    35641 ttatacagat gtagattttt gtttagctca tataagagtt ggaaaacttg aaatgagaga
    35701 actagatgaa aagatacctc taaaacatgg ggtagttggt caagaaactt gtggaccagg
    35761 tggaatagct tatggaatga ggtctataga aggtgttctt gaaaacatag attatatgga
    35821 aaagtattct ccaaattgtt ggatgttaaa ttattctaat ccagcatcaa taatagcgga
    35881 agctgttaga aggttgagac ctaattctag ggtaataaat atttgtgata tgccaatagg
    35941 tatggaacat aatatagcaa ggattgcagg actcaaatct cgtaaacata tggatataag
    36001 atactttgga ttaaaccact ttggttggta tacttcaatt aaagataaaa aaggaaatga
    36061 acttttacca aaattagtag aacatataaa agaatatggt tttataaatg gtgaagaagg
    36121 aatgaaaaat gacaagaaag atagttggtt tgaaactaat ttatttacta aagaaatagt
    36181 aaaaacagat ttaactacaa taccaagtag ttacttaaag tactatctat ttccagatta
    36241 tgttgtaaat cattctgatg taaattatac tcgtgccaat gaagttattg atggaagaga
    36301 aaaagaagtt tttggttcat gtgcattgat agaaaagcaa ggacattcta agggcagtgg
    36361 gcttaagata ggaatacatg cagagtttat agtggattta gctacagctc tagcttttaa
    36421 tacacaggag cgtatgttat tgatagttca aaataatgga gctatagaaa atatacaaga
    36481 tgatgctatg gttgaaattc catgtatagt tggaaaagac gggtatgaac cattatcaat
    36541 agggaaaata ccaacattcc aaaaaggttt aatagaacaa caattagcag ttgaaaaatt
    36601 agtagttgat gcttggattg agaagtctta taataaattg tggcaagcac ttatgctatc
    36661 taagacagtt cctagtgcaa cagttgcaaa agaattacta gatgatttaa tagaagcaaa
    36721 taaaaattat tggccaaaac ttaattaaga ataatatatt tttaaagttc ctacagttta
    36781 gtacatagcc tagttaatgt atttgtaggg actttattta tttacaaatg agatacaagt
    36841 ggcaaacata gtgtattttg cagttaggaa agtaggttta gttacttgtt agttggatta
    36901 aatttaggta caataattta ctatcaatca atagaaataa ccagagaagt tgcataataa
    36961 aaaatttaca cttttaacag gatttatgta ggtgtttata gaaataaata aatatgtaca
    37021 taaatacata attattttta agtctaaaat acaagaatgg agagatggct atgaagtgga
    37081 gagattatgc tgatgatgta aatttatttg aggattttga taaaactatc aagcctctaa
    37141 ctgacgaaca aagaagaaaa aatataaaca ctttaattgc atatttttca aaagaagttc
    37201 cttctaaaat atacaattta tcaaatgatg aaattaagcc tagagatata cttagaggac
    37261 ttttgaatgt atatccacca aaagaaattg ctccagagat acttaatatg ttacataatt
    37321 tattgttgat tgaatgtgaa gaaagagagt tagtagatgt aaatgatata gaagaaatag
    37381 aggaagggat tgccatatgg agaggtaata taacgaattt aagagcagat gcaatagtaa
    37441 atgctgcaaa taacaagtta ttagggtgtt tacaaccatt acatctatgc gtggataatg
    37501 agatacattc atgcgcaggt cctagactta gagaagattg tgacaaaata ataaaaaaac
    37561 aagggcattt agaatatact ggagatgcta agataactag aggttattgt ttacctgcaa
    37621 aatttgtagt acatactgtt ggacctattg tatctggtgg tcagccaagt aaagagcaag
    37681 aaaagcaact gcttcattgt tataaatcat gtttaaatac aataaaagaa attgatgaaa
    37741 taaaaaatat tgttttttgt ggaatttcta caggtgtatt tggttatcca aaaaaagagg
    37801 cagctaatct tgctgtaagt agagttagac tatggctaaa agaaaatcct gaaaaaaatt
    37861 taaaagttgt atttaatgtg tttactgaag aagaagaaga gaaatataga agaatattta
    37921 aataatatta tgtaacagaa tcctaaaaat acttattata taatacaaat tcattgtata
    37981 agataataat ttacaagtag taaaaattaa taaaatataa tt
//
LOCUS       DAMJWC010000038        36580 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMJWC010000038 DAMJWC010000000
VERSION     DAMJWC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36580
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.038"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..254
                     /locus_tag="PC503_002163"
     CDS             <1..254
                     /locus_tag="PC503_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2528135.1"
                     /translation="KKQVQNCTVLESIFFYKNINPNTVQKRIRVNKIERYISIDDIKK
                     DLELDKEDKSLERAIKHTKDRMLNSLDEEEKLLLLKGLM"
     gene            complement(872..1258)
                     /locus_tag="PC503_002164"
     CDS             complement(872..1258)
                     /locus_tag="PC503_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528136.1"
                     /translation="MCEQIQEENIKDRIKEIREDAGLSQKDFGSKVKLSRSQISCYEK
                     GIRDATDRSIKDICREFDVNENWLRFGEGEKYSINEKDSLLAEVLAEITISDNMPMKE
                     IIIKLCELDEEYLDLINKLIDGLLKK"
     gene            1425..1595
                     /locus_tag="PC503_002165"
     CDS             1425..1595
                     /locus_tag="PC503_002165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528137.1"
                     /translation="MREEKIKTIVRKINFLDEFGLEIVNNIGDLCIKDQKNKKKSNSY
                     NLENIISIDKLD"
     gene            1681..2283
                     /locus_tag="PC503_002166"
     CDS             1681..2283
                     /locus_tag="PC503_002166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528138.1"
                     /translation="MEINSVRELRELVELFGVIKAESNNVVSCNETVNELSNKELIKA
                     NENKFKKPWNDALLYEINALDIIKKHKHSDRKEKAYKTYLGLENADIEEIYKIHYGDK
                     ENSETVASCEEISSAKTDTISCNHDSVSKGKDTSDSECTCFICSKKIENQEDVFKIPF
                     LTRDYLSSAKEIKNIEICEKCLDGNSWSIIRRKQFKKMKK"
     gene            2329..2610
                     /locus_tag="PC503_002167"
     CDS             2329..2610
                     /locus_tag="PC503_002167"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528139.1"
                     /translation="MIKNNVLSYEEKIKVLKKHGYSDFTKEYVLKEFDKEHAFYKSFL
                     RAIEKEDDGKGVLIKKIGKGQHQFSKGFIKTHTISELLEEAKRIRKILE"
     gene            complement(2649..2993)
                     /locus_tag="PC503_002168"
     CDS             complement(2649..2993)
                     /locus_tag="PC503_002168"
                     /inference="COORDINATES: protein motif:HMM:NF022172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2513 domain-containing protein"
                     /protein_id="HDF2528140.1"
                     /translation="MVTNQDCIRDILLLIESNTTPISPVLQFDTILDNLTYDKSTIVH
                     HINLIYQNNLVDDVNYGDDTVLEVMQLSLKGYQYLDKIRDNTKWNKIKSSTSSFLNMS
                     LPIAIEYILGKF"
     gene            3082..3258
                     /locus_tag="PC503_002169"
     CDS             3082..3258
                     /locus_tag="PC503_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528141.1"
                     /translation="MQKRITEMSILEKVDLIGQKQKKLQEKYKNLSKGELFSIACNEV
                     KKIEEQEGKYFEYR"
     gene            3284..3610
                     /locus_tag="PC503_002170"
     CDS             3284..3610
                     /locus_tag="PC503_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528142.1"
                     /translation="MEELKEEIKQKEENLKEREKYIKELKERLECFARDALESEECII
                     DIENILIEQTVELEAYNLFIDCILNKDIRKAIAIYNRTKSIRIKHKNINSISKKIEKI
                     KQIISL"
     gene            3630..3803
                     /locus_tag="PC503_002171"
     CDS             3630..3803
                     /locus_tag="PC503_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528143.1"
                     /translation="MDKFVTCARCERTINVEENNHVKYEEETLNLSFTLYFCLGCVDK
                     LIEQSKMLEGENE"
     gene            3796..4011
                     /locus_tag="PC503_002172"
     CDS             3796..4011
                     /locus_tag="PC503_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528144.1"
                     /translation="MNKISVTQALEKFDSLLDNWNDLPNHVYTLEYRSKFYEWIKLLE
                     RKGSLQNYKIVEVLNAERNGEEASFWN"
     gene            4070..4243
                     /locus_tag="PC503_002173"
     CDS             4070..4243
                     /locus_tag="PC503_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3797 domain-containing protein"
                     /protein_id="HDF2528145.1"
                     /translation="MKMINVFKLSSMYCICPKCGSDKLGEGEGKLIVDEHTYYRECKC
                     GFNVLVDEREDEI"
     gene            4258..4665
                     /gene="ssb"
                     /locus_tag="PC503_002174"
     CDS             4258..4665
                     /gene="ssb"
                     /locus_tag="PC503_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2528146.1"
                     /translation="MNSVILIGRLTKDPELKYIPGSGTAVSTFTIAVDRDYIKKDGTK
                     ETDFIPIEVMGKLAEICANNLTKGRLIGVEGSIRVNSYEKEGEKRTYTKVHANKIKFL
                     DYKKEDNEKEYMFEPKGLDQQGFQAIDDPDIPF"
     gene            4682..4861
                     /locus_tag="PC503_002175"
     CDS             4682..4861
                     /locus_tag="PC503_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528147.1"
                     /translation="MSNINKKTAKICGWCGTTVYSYVDGKIAYCSKKCKKKREKNLET
                     EGAKNEKNKNRRIYY"
     gene            4827..5117
                     /locus_tag="PC503_002176"
     CDS             4827..5117
                     /locus_tag="PC503_002176"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528148.1"
                     /translation="MKKTKIEEFITKVKESMQSVAKESIKDLENILKEIETGETEVKI
                     LFIDKEKKVEEIVEFTHDEYVKMIIEKMIFDSLKIIKEQHEKILKEFEEREV"
     gene            5120..5380
                     /locus_tag="PC503_002177"
     CDS             5120..5380
                     /locus_tag="PC503_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528149.1"
                     /translation="MNFKMIANIPKWTVKEQFEKVLEEVLELKEAIELKDNKKIMEEG
                     LDVIQAIFTLFKVLKIDKEIREGLKLHNKKLRKRKWKLEKIN"
     gene            5398..5607
                     /locus_tag="PC503_002178"
     CDS             5398..5607
                     /locus_tag="PC503_002178"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528150.1"
                     /translation="MSICRKCLYGDYLDELVVGECILCGQEFFSIKTPVGKMCPSCSE
                     MFKGNCSQCAKPIGNEKKSFKNKLK"
     gene            5850..6311
                     /locus_tag="PC503_002179"
     CDS             5850..6311
                     /locus_tag="PC503_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528151.1"
                     /translation="MKIKKEYFDKVENALKMLGDKYRKLRVLKKEIAILKHKENYREI
                     NYEELGFKVQKSVKGIDDMVVTIEDAIYNKETEIEIIERKLEFYNIYLKELSEIEQKI
                     IELVYFYSWNGKMPITKMAMELNYDRTSLYNKKAIAINKIALMIYGDEALE"
     gene            6491..7039
                     /locus_tag="PC503_002180"
     CDS             6491..7039
                     /locus_tag="PC503_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2528152.1"
                     /translation="MNFVEPIRNLEKLESICAYLEETNMRNNVLFSMGIYTGLRVGDI
                     LKLRIKDVHDKRFITLKESKTGKTKPIEVNPILRRILKEYTKDKNQNEFLIKSREQTN
                     KAISRVMAYKIIREVGEMFGIDNLGTHTMRKTFGYHYYKRTHDVVTLQKLFNHSSATI
                     TLRYIGIEQDDLNKAYRNIKYF"
     gene            7212..7484
                     /locus_tag="PC503_002181"
     CDS             7212..7484
                     /locus_tag="PC503_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528153.1"
                     /translation="MNKYGKFKCNNCGKKVNVNNRDLKTKVIDNTTVTYFMCRRCFEK
                     FVVSCEDDYIKHKREEYKKLKDDEVKLLQDMKEYSDGLGELYINEL"
     gene            7474..7806
                     /locus_tag="PC503_002182"
     CDS             7474..7806
                     /locus_tag="PC503_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2528154.1"
                     /translation="MSYKHMTLDRLKELILIDRLDIFYRSTDWRKLRKKALERDNNEC
                     QICKEKKKVSKAECVHHIKEVKEYPGEALKLNNLTSLCNLCHNEIHEKILKINQEKKK
                     KFFSEERW"
     gene            7978..8484
                     /locus_tag="PC503_002183"
     CDS             7978..8484
                     /locus_tag="PC503_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012720579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HDF2528155.1"
                     /translation="MDDNEELEIRRDVQNDYVLGMTYKEMSAKYNIPENTLKSWRKRG
                     GWTRNCTPKKGCVKNGLQESGNNLKNSIRKDLLRQIKENNMTEEYFKDLVEDYLKMWD
                     IKNELIEDVKTRGVQVKYKNGQNQWGYKKNDSVSELIKYNAQMLSLLDKLGIKATPKV
                     LGDDDIEL"
     gene            8468..10096
                     /locus_tag="PC503_002184"
     CDS             8468..10096
                     /locus_tag="PC503_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDF2528156.1"
                     /translation="MILNYKYNKYIDEYFNLVDKGEIVLCKEMELAVKKIKKDLKKPN
                     IYIDHEKVEKAIEYMEKYFYKMYAWEKFVVALVVGCFEGDELLYDEIFIMMGRGNGKN
                     GFISQLANYLQTHLHGVKNYGIDIVAMSEEQAKTSFDDVYNMLSEHPAICKKFFNRTK
                     EVITFKKTNSYLKFRTNNAKSKDGLRPGCIIFDEVHAYENYDNIKVFTSALGKVKNPR
                     IFYITTDGNVRGGVLDDFKEESKQILNEEIKNSKMLPLIFKLDSIEEMENIDLLEKAN
                     PSIKYNSDLRTQILKDIDKAKNRPQMMIELLTKRFNLPAQNLATVVAEWDDIVATNEE
                     LPDLKGFSCIGGLDFSSIRDFTSVVLLFKKDKKRYIMHHTFICYKSLEITNFKFDIEL
                     AKQKGLCTIIYDETIKAEYIADWFIEKAEDYNILKICCDSYRAAHVKEEFANKGLPIE
                     EVRNGSITHAKIAPLVEQIFAERTIKWGDDMMMRWYTNNVYVDTDKKGNKTFLKIEPI
                     KRKTDGFFAFLHALSKDDELMQESTIKFYDCYTY"
     gene            10115..11305
                     /locus_tag="PC503_002185"
     CDS             10115..11305
                     /locus_tag="PC503_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2528157.1"
                     /translation="MNFKNFITNFLFKDKMSGADGEYFKKLEATIFYKEFALRSCISI
                     IANALVLSEFQTFKNGKSIKEKNYYLFNIEPNQNQNATEFWQEVITRLVYDNECLVIQ
                     ENEQLFVAESFSVDKYVFYEDIYKDVTIRNYKLDRSFRESDVLYFKLNVESIKTVIDY
                     LYNDYKDLLSSAMKGYKKNNSEKGVLEIDTNYPQTKEAQERLNDLMGNKFKLYFESDN
                     AVLPLSNGLKYTENTKASSIKDSRDIRAIIDDVMDFVCAAFHIPAGLVKGNISGVEGI
                     TDNFLNFSINPIARLITTEITRKMYSRDNFFEKSYVKVDTQKIANMGLEKISKASDLL
                     FRIGVNSINDNLEMLGREKINESWADEHYVTKNYQSILNPDLKGGANNGNGEKSGIAG
                     NKGQ"
     gene            11259..11894
                     /locus_tag="PC503_002186"
     CDS             11259..11894
                     /locus_tag="PC503_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDF2528158.1"
                     /translation="MEMEKRAVSLEIRDSNLESRKISGYAAIFNDDYTKLQDRWGDTF
                     YEKISRGAFLKTLADNTRDKFMLINHDWNKVIGRTNSNLILEEDERGLRFELDIPATT
                     DGNDLLENVRLGLIKGCSFGFNIVNSKTRFDDDWTYYRDITEVELFEITATPIPAYND
                     TEINCRSDISIKELRESQKEEAKQNDNKDNIEKRNVDLVSAFFNAFNRGGK"
     gene            11898..13064
                     /locus_tag="PC503_002187"
     CDS             11898..13064
                     /locus_tag="PC503_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDF2528159.1"
                     /translation="MAIKNLDEATNVELRTNLMEAIKSNDEEKITTAFLRMAEDIQSN
                     LLKEARSIANTESIDRAILDKRGMPQLTSEERAYYSQVIEKRGFTDLEITMPRTIFDR
                     VFDDLEQNHPLLSAITFENTTGVTEWVIRKTGTEAAWWGQLTDPIKKELEGGFAKINT
                     VAYKLSSYLPVAKSMLDLGAEWLDRYVRVVLTESISLGLEMGIVAGTGKDQPIGMMKD
                     LKGSVVEGVYPDKTAKPLADFKPNTLGTEIMAPLTNDGKRTVASVIMLVNPVDYWAKI
                     FGATTMLTSNGTYVYGVLPIPGNIIQTVAVPKNKLIVGVAKDYFMGIGSAGKIEYSDE
                     YKFLEDVRVYLAKQYATGTPKDNFSFLVFDIENLDTTLATEINSNTKTSATRAK"
     gene            13074..13367
                     /locus_tag="PC503_002188"
     CDS             13074..13367
                     /locus_tag="PC503_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528160.1"
                     /translation="MENENIKNIVEEVKEYLNITWIEEDAKIEKMVVRGINYLENEIA
                     GIALDFKDNFNRELLFNYCRYVRNNAIEYFEENFSKELFRLQIKSAANEVTKI"
     gene            13364..14014
                     /locus_tag="PC503_002189"
     CDS             13364..14014
                     /locus_tag="PC503_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HDF2528161.1"
                     /translation="MKKIKFDNFNDGIIEFGEYKESYDIEGNALDEKKFIVNGKLFYS
                     NEYIREQDRLKFDNTGLKVSIKLKVPYMKLIKTSDVIKLNNEFYSIVKLDISNDKTSI
                     YLYLSELVDVLDKHISIFIKERKNVLEDVEMKFYKKVWACVEDLNSKELIENNSIKTS
                     TNKKFKIRYIEELDLSIKQNAITNFVIKYKDKFYNITQILNLEEENKILEITAESK"
     gene            14031..14357
                     /locus_tag="PC503_002190"
     CDS             14031..14357
                     /locus_tag="PC503_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528162.1"
                     /translation="MHSKIVTILEKLNIGIGFQEYDNFSNDEEYIIFFIENEYDANFS
                     DNENKSIVYSIKIEYWYKSLKNINKYISIKDMFKKEDFIFLNSSDFIENEYYCKELKF
                     KYEEVI"
     gene            14358..14801
                     /locus_tag="PC503_002191"
     CDS             14358..14801
                     /locus_tag="PC503_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2528163.1"
                     /translation="MSVEITTEGFDAILSKIESMGKSGDKLLNEAVKAGGNVILQDAL
                     PRVSKRSGKLKDGLKVSGVKKKGGTKYVLVGITKEDNSKIFYGKFLEFGASAHKIPIK
                     KGKKKGRVVNHPGVSPKPFLAPAYESKKDEAKNVMKEILKRGLGL"
     gene            14801..15136
                     /locus_tag="PC503_002192"
     CDS             14801..15136
                     /locus_tag="PC503_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528164.1"
                     /translation="MININDLVIETLKPLKIPVSFQRFDGEEKTYITFFSYLEQNRYA
                     DDEVVGTEHYIQIDLFSKNKMSYINKEIERLLKKNNFIKRSIHEIKESDYSYHTIFRF
                     LFFAKNEED"
     gene            15140..15736
                     /locus_tag="PC503_002193"
     CDS             15140..15736
                     /locus_tag="PC503_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2528165.1"
                     /translation="MAIIGLRNYRLVKLLVDTESELEYDTKIMKLTGAKNIKIAPKVD
                     SAENYGDDQLLETASAMGAIEVEFEVASLTLEEKAFILGYKYKDGVLVEDKDFNPPNI
                     ALGFESPKSQGGNRMVWLTKGVCEPLEEEAKTKEDKVEFQSQKIKLKFMPRINDGRHK
                     ITADTDVENSPTAEEFFATAFLKTAAKPTAPAKTNLNK"
     gene            15751..16038
                     /locus_tag="PC503_002194"
     CDS             15751..16038
                     /locus_tag="PC503_002194"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528166.1"
                     /translation="MEIKLTINEEEKIFKAPPIALRKLDKVFTLTDKIEDGLNSTELF
                     RELLDFTVDIYGEQFSKDELLDGFYPAGDFINKALEDLSKVSGGFEEKVKN"
     gene            16122..16277
                     /locus_tag="PC503_002195"
     CDS             16122..16277
                     /locus_tag="PC503_002195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528167.1"
                     /translation="MFLFEKNWSMTDIDNMDIFYYLDILVYMKENKKDNNNPNENDVY
                     IDQISWL"
     gene            16290..16508
                     /locus_tag="PC503_002196"
     CDS             16290..16508
                     /locus_tag="PC503_002196"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528168.1"
                     /translation="MCKYCEVKINTEPFSMYDTVVRGELLTNDSDIDMYIELKNGKHF
                     LTGASYDYLGISSKETIKYCPFCGRKLI"
     gene            16577..21778
                     /locus_tag="PC503_002197"
     CDS             16577..21778
                     /locus_tag="PC503_002197"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDF2528169.1"
                     /translation="MAEDVGELVVRVAMENSSFQQGVNNLNRQMKLIRSEFKNSGAGV
                     KNFGTSLDGLKSKQQMLSSTIQQQTKVVEAYKNKLNESKTTLSNTAQKQVELKEKVNQ
                     AKSAYEQSKATLGENAEETKRLKSELDSLEQEYAKNEEKIRSNSAAVDNWSIRVNNAE
                     SRLSEMRSELDDTTERINQQENKWNQLATKMTEIGNKFSSVGKQMQDVGKKMTMSITA
                     PILAVGAAASKLGMDFEASMSNVQGLSGATADEMVQLEKAAREAGASTSKTAKDAADA
                     LGYMALAGWDAKTSMEALMPVLRLSEAGNLDLARTSDLVTDSMSSLGLSVKELPTYLD
                     QVAKTAASSNTNIDALMEAMIVSGGTFKNLNVPLSEANALLGILANRGLKGSEAGNSL
                     NSIMINLTSGAGQAGVAMKELGLSAFDSNGKFKGMANVLMELKEKTKDMTEEQRTMYL
                     SMIGGKTQISTLQALLSGVGEEYSELEKKVGNSTGALDKMAKTMQNNNKGSITALISA
                     VQELGLKIYNVLKPSIAQAVSWFQNLTNKLNEMKPSTVETIVKIAGLAAALGPVLLIG
                     GKIVSMIGGAIGAFGTFSAAMAVVTTGAAAATPAVGALAAILGALSSPAAVAIAGITA
                     LGISVATVAKDMSKDAIEPISRFGKSVSESTKEAVGAFMDLEEKTTISLNQLMWSGET
                     VSEKMKQSIVSNFTEMSNQIIAKLQESKEQGIQSLQEMFATSKNLSDKEKEELIKNTE
                     EAYSSKEEKIKKSNEKVNQIMTKASQEHRTLTKEESAEINQIKTDMLNTAVVTMSKSE
                     AEQAAIMERMKANHVDLSAKEAAEVVKNSIKKKDESIKAANEEYNERLKIAAQLRAEG
                     GAENEKLADKVVEEATRQKDESINKAKEMHQGVVAEAQKQAENQASKVDWTTGEIKSK
                     WQVLNDTVKGKMQEWDDMAGNWVEGLKEKISTGWANLKENTAILWDNIKLTVTTKWTE
                     IKESIAFKIEEIKQSISEKWESIKLFFTTTWENIKMIFGNAWDAIKQQVEEKFAPFVE
                     RLKIIFDGIKEFFRSTWEVIKNIVLGAVLLILDLVTGNFDKLKTDAIQIWENIKQSLS
                     DAWESIKEVFNNALTAISDLLSNMWEGMKSTASSVWESITQTLSSIWENIKSTCSNAW
                     EGLKTICSNTWTNIKTTLVTSWENMKTAVSTKLTEIKNNIVTVWNSVITFFKTLPAKL
                     KQAAIDMFTRLKEGIDSKKQDAVNASQKVGTDVVNKIKEFPSKFLQVGKDFVSGLANG
                     ISGFAYKVVDEAKKLGQKAADAVRKVLGIHSPSRVMAEIGKFVDEGLAQGIANNSDSV
                     KKATEKITKIIEEETKKATKACEEDIKLFNKQIDELSKQEKAALKKVKGDAKDALKEE
                     YAAKKEKIKEAIALRKEQKEKEVEQLKEIANSAKEQLNKELQDRQEFVKKVDDLTKAI
                     VDALKEKYKQEYEAQQASIKKELDALDKWKEESIDRINSVYDAKIKAIDNELEAFEKA
                     EKEKDRLEQDKEELNKIEEIKTAIKFEHDDTNKEQLQKELEKVLAERKKRIEQQEIED
                     KKEALKKRKEELEEKKKDEIENINQIYESEKEYYNKRLEDAKKFYDERIKESKLQAEA
                     EKLIMDKNQKEIVALLNSYSDAYKNAGQTLGEKLLEGFKPAINEIKNLIDSITREINN
                     ARNEALSLNSDIRKGNSAANSNSGRREATYNNNSRTANYNVNVNSTDSNTAREIERTI
                     RSLAFSL"
     gene            21810..22676
                     /locus_tag="PC503_002198"
     CDS             21810..22676
                     /locus_tag="PC503_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015957549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDF2528170.1"
                     /translation="MQKLICRNSKGQEVKLGNSRPFLLEKIENGANTSANISVSNNLG
                     DGVSIDDISIKERLLPISAAIYAKNKEDLELKRAYLTSLFNPKLGEMEFIYTNNALTK
                     RVKGVVQDITFQTPVGLMQKFLIQLLTPSPFWMDEFVLKEEVALWVGDFEFTLEISNE
                     GIEMGHRVSNLICNVVNNGDVECGMKIQFKALATVDNPSLFNVNTREYIKINRTLEAG
                     DLLEITTEFANKRIELVKSNYERINVFNWIDLDSEFLQLEVGDNLFRYDADVGIDNLE
                     MSIYYNPLYLGV"
     gene            22678..23757
                     /locus_tag="PC503_002199"
     CDS             22678..23757
                     /locus_tag="PC503_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus ReqiPepy6 Gp37-like family protein"
                     /protein_id="HDF2528171.1"
                     /translation="MQQSIRILDKNINLIAEIDNYEELQIIKKFHKVGEFSLKINANK
                     NHVDKLVKNNIILLGKNYNKVCLILHREFMYTETGEKSDILSVKGVDLKGLLNRRLII
                     PDTGEAFESHEGTQEEIIKAFVNNNCVDSSNPKRVIDNLIISENKNLGSADMWRSSYE
                     NLSDKIQEISEFCGLGWEVVLDANKKKFIFDVITGKDLTINQTENPPVIFRSDFNNIR
                     ARHFTESIINSKNVVYAGAREDATKLVISTGEVEGFERNEVFADVSENTISILQKEGE
                     IKLKEYEELKSFELEIDPKNTFMYEKDYKLGDIVTVQDRKLKVTMDTRIVEVQESYSK
                     NGMKLKITFGSSIPTLFSKIKRMVK"
     gene            23757..24644
                     /locus_tag="PC503_002200"
     CDS             23757..24644
                     /locus_tag="PC503_002200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528172.1"
                     /translation="MEKSFVFNSVNGDRRYKAEDFREYFASFIGNGVFPNPSSNLQVV
                     DNNNNNMTITVKKGKGWINGAIYINTDDLVINIDPADGILNRIDRVVLRFDTLNRNIK
                     LAVKKSAFNSSPAATELQRDADAYELGLADIYIRAGAISITQSSITDLRLDKNLCGIV
                     KGTIEEIDTTTLLAQLSTWKDEEISNFNDWRENQENKQEDWYNTTTTNFVSEFNIWFE
                     SIKDILDEDAAGNLLNEINKVKEELAKIETTAEKTSYNNATSNLTATNVQGAIDEIVA
                     KIENFNEINISIQNDMLPI"
     gene            24661..26349
                     /locus_tag="PC503_002201"
     CDS             24661..26349
                     /locus_tag="PC503_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528173.1"
                     /translation="MAIVYEFNYTGAEQSVVLPPGKYKFECFGACGGNYYDFVQCAKG
                     AYTAGSLILKENTTLHVYVGQSGYCKGVNGIETCRSGFNGAGGITTYKSTSDGYYSLA
                     GGGATDIRLIGGNWDNLQSLLSRIIVAGGGGGGSGNSHDSIGHGGGTKGKDGISIANK
                     YFAGGGSQFQGGLTFNSLYNGSFGVSGAGDGISGVGGGGGWYCGAGSFYAEFGGGGSG
                     YILTKDSYKPANYSPSSKYYFSDINSVVGGNTTKQDGYAKITLLQALPFLTISSYNST
                     TATFKADHTDPTLLTKIEYFIDDVLKETITTDLTLEKTINYTLEDNALHTLKIVVTDS
                     ANATAEKVVSISKGIAPLPAGSTTDEVTSKWIEIKDAFKSGKTSIINTLALKNIEASL
                     NNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNTRYKVASGITYQLNNPSL
                     SANFYNGGYTTTQDHWINVSNLGFVPHIFIAECDFTKDGYLTKSLVFASYNVFSKDYV
                     ISSYFRRQTNSTFYSHGNIYNLNEKDVYVNGRGVQLPAFNNYDFAYKWQAIKFV"
     gene            26363..26656
                     /locus_tag="PC503_002202"
     CDS             26363..26656
                     /locus_tag="PC503_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528174.1"
                     /translation="MNRANRIIYDQTGKMLLQTGEATGDVLEYDTITELHCIDIPYGS
                     IDYTKNRIIGINIETKEPILEEIPVFISEEEKRIQELENQILLNENEKVGGIL"
     gene            26656..26838
                     /locus_tag="PC503_002203"
     CDS             26656..26838
                     /locus_tag="PC503_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528175.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFELDDVTNAEYRKAVED
                     YIIEHSGVVEGTQPTK"
     gene            26901..27332
                     /locus_tag="PC503_002204"
     CDS             26901..27332
                     /locus_tag="PC503_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2528176.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPRKLKDRIGSLLDTMTDELNVKGGSK"
     gene            27332..28171
                     /locus_tag="PC503_002205"
     CDS             27332..28171
                     /locus_tag="PC503_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2528177.1"
                     /translation="MKICITVGHSILKSGACTSANGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKIYKIPRVNSGGYDLLIELHLNSSGVGAFGTEVFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGVKLDKSLYILNSSKPTAILIESFFCDNK
                     EDYEKAKKLGHEGIAKLIVEGVLNKNINNEGVKQMYKHTIIYDGEVDKIPATVVGWGY
                     NDGKILICDIKDYVPGQTQNLYVVGGGACEKIGSITKEKYTMIKGNDRFDTLYKALDF
                     IDR"
     gene            complement(28222..28434)
                     /locus_tag="PC503_002206"
     CDS             complement(28222..28434)
                     /locus_tag="PC503_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528178.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            28613..29443
                     /locus_tag="PC503_002207"
     CDS             28613..29443
                     /locus_tag="PC503_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528179.1"
                     /translation="MKTLFKEAHKIAREIKEKYNDVDYKVQFSLCLSFLNKKGDIKMK
                     ELKGSEKQIIWANDIRADILNLTNELEKSKLERIKNEDYKIKDMSIEEMIERCKRKFE
                     RIREAISNIEDAKFFIDNFRNVLKYNSLNQKAFQINQIFRESQFTEEIGNLKFLKGET
                     QASHKLRKVEGSISYEEAKKIAKEINFNDNWSNEIKENVLEIVEIFDDAVKQATSTEY
                     IEKAKKYIIETLIQKNAQFYRNGFADIKKKQIENYRKIESAERKIEIAYQIFRDGVEC
                     "
     gene            29522..30025
                     /locus_tag="PC503_002208"
     CDS             29522..30025
                     /locus_tag="PC503_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528180.1"
                     /translation="MNIDFSTILNLKVNKENVEMIEKEINKINNDIFDISLKDCANGH
                     VGIVKETVGKSLNIETWGHGEINSSIGIRLRFNFYYSKGDKVDIENIENILIYVNSLC
                     SKNVESDLIASVRPGFYKLEEKYSTRIEKCEIRHEFTGINKQEIKEFLEYLTEIEKSE
                     RTVIYKK"
     gene            30049..30519
                     /locus_tag="PC503_002209"
     CDS             30049..30519
                     /locus_tag="PC503_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528181.1"
                     /translation="MNKQKARRFLRVIDMNMDKIEEEAIKAFKESCLIKETNNIKIYI
                     DIQGKVEAIAVQTWAKLLDDDKEINIFTLNQTPTHLNDLFGEICYVNDYEEFENWCEN
                     EREILDWDSYKKFNKENFEEIAERNIDDSTSVFLEELQKSIESCKQELQNIVEN"
     gene            complement(30822..31103)
                     /locus_tag="PC503_002210"
     CDS             complement(30822..31103)
                     /locus_tag="PC503_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528182.1"
                     /translation="MNVYLQIGKELSEKMTKSELNKFSQEVANYLQYAGLDKNMKIKL
                     FQTILEMVARKKITLSSDSEFTEGILQSDEAEMTMNVGFIIEGLSYHNN"
     gene            complement(31246..31581)
                     /locus_tag="PC503_002211"
     CDS             complement(31246..31581)
                     /locus_tag="PC503_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528183.1"
                     /translation="MPKFDEELLSNKEKPVFKKNGTIIQNNSTTTDNKTLNIYNLVNK
                     KSKKVTMSATLDEELVNKLKSFSIDMNSDVSKLLSDVLTQILSDVTIKEENLNIYNER
                     NRRNKTKKK"
     gene            complement(31582..32391)
                     /locus_tag="PC503_002212"
     CDS             complement(31582..32391)
                     /locus_tag="PC503_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2528184.1"
                     /translation="MANTKLLTYFNIKGGIYKTTTSIMTAYELAKDKDKKILLWDLDV
                     QANLTQYVYEINHNDNTTLDILKGISANDAIVKSPNEKYINVDLIPSDIQMARFEQEL
                     SPLPAREKFLARWYMQNFNTLSEYDYIICDLSPRYDLTAKNVLFLADSIIIPIQDKNI
                     SSLRGAELFKQLWDVDRTYFDKEDNIKSTVLVGFEKKKTQISDTFDSYLEGFNDMRDI
                     MLDTYIRKNEFIEKALLKKLSLTDYTKITKEHFSRQEFANMLEELKVKGVL"
     gene            complement(32680..32862)
                     /locus_tag="PC503_002213"
     CDS             complement(32680..32862)
                     /locus_tag="PC503_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDF2528185.1"
                     /translation="MEKEKRDLKFNFHKGGSGSFTPRMSVPKKWADEMGITRENPNVT
                     ATFEGDRIIIEKAKNE"
     gene            complement(33684..33836)
                     /locus_tag="PC503_002214"
     CDS             complement(33684..33836)
                     /locus_tag="PC503_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528186.1"
                     /translation="MDNFLLNVLAGVIASLIFYIISKLFRQVKNHSAQKSGWEFDLRI
                     KFKKFK"
     gene            34356..36521
                     /locus_tag="PC503_002215"
     CDS             34356..36521
                     /locus_tag="PC503_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2528187.1"
                     /translation="MKNVNKNNIDKMFLEECSAERAEHEKENYSNFNRHETYEIKKYI
                     NEKKLGIKTAIANAINGGKTLFIAPTGAGKSYSFINTLKKLKTKALFILPNASNVEQA
                     MHEYDIPGAYDKIPVSEAFKNGNLVVMTWDKTEKLINTDLSEYIIVVDEIHQTYTDAY
                     RGKAIKNLNNIMSKCKGRIDITATPTKLEFEIYDYIIEYTQKQKTEYKVKLYNDFDNK
                     NFTEMINIINKSKNSAMLMNDISTLEFIRDSVNKKVGVVYADGKEENELYNRIVKNSD
                     MKDYETLLNTTTILAGVNINNKDITDIIIVNIKDVGAIKQYVARFRNLKKVNVHIFNK
                     YEEECNVYKIEWLVNKNIEKATILKDAYNKVSKHMLQFETVGINATPIRIDSNVYYCT
                     KDNCYKVDKLYIKSQVYSNYYNTRTIQSFKVLLEEYFENVNITDAKEVGTNEKELKEY
                     KKVVKEIKDATREILKEHKEILVGYRQIKSDSKSFSLMQYHNDMKLSSKGCLEAYRAY
                     DIHNLVKKSKSNSMLELYSNYVLDNKFDLDLAWKLANTANKRRGVIFNKINTLIYREL
                     KEEYPEFLNDELIQVTVFNYIDKLFGIGTSYKELHLQELSNDLRTILGENWDLTTKKL
                     SVTLNGIFIIEKKKYSNWHDIETMFFYKNINPISCQFEKKRIQLNNIKRYITVDDIKK
                     DLELDEKDKSLENAIKYTKDRMLNSLDEDEKLLLLKGFM"
BASE COUNT        15047 a         4106 c         6486 g        10941 t
ORIGIN      
        1 aaaaaaaaca agttcaaaac tgcacagtat tagaaagtat ctttttttat aaaaatatta
       61 atcctaatac tgtgcagaaa agaattagag ttaataaaat tgaaagatat ataagcatag
      121 atgacataaa aaaagattta gaattagaca aagaagataa gagtttagaa cgtgctataa
      181 aacatacgaa agacaggatg ttaaactctt tagatgaaga ggaaaagcta ttgctattaa
      241 aaggattgat gtaagaatat aaaaaatgtg tccatactta gaaaatatct tttttacaaa
      301 aatataaatc ctatttcatt ccagttttaa ttgagtaaat tagatgaaat tgaaaaggcg
      361 tttttaaaca atgaatttga tatagggttt aaaattgaaa aagaatcaaa agaacaatta
      421 gagatttgca tctaaacaaa aagccggggt taggattata tatatattaa atcctaaccc
      481 cggctttttg atgcaagatt aaaatttctg accttacgat ttttatatac aagaaaattc
      541 agtatttttt gaattggaaa tattttccag tagcaaaatt tgctaaaagg tactattatt
      601 gtagtataaa tgtttaatta cgacaaaaaa tcgcacatgt gttcttgtaa tatcgaacaa
      661 aagggggtat aattaaaatt gtaagttatt ttttacaaat tttaagaatg tattattcta
      721 cttgtatata gggggatgat ttggttgaaa gaggacgagt ttagagaaag aatagtatca
      781 attataatgc aaattaataa tattaatgtt ttgaaattta cctatacata cttaataaaa
      841 gcaaaaaaca agtgctaaat agcgcttgtt tttatttctt taataaacca tcaattaatt
      901 tatttattaa atcaagatat tcctcatcaa gttcacaaag ttttattatt atttccttca
      961 ttggcatatt atctgaaata gttatttctg ctaatacttc tgccagtaat gaatcttttt
     1021 catttatcga atatttttcg ccttctccaa atcttagcca attttcattt acatcaaatt
     1081 ctctgcaaat gtcttttatt gaccggtcgg ttgcgtctct tattcccttt tcgtaacaac
     1141 ttatttggct tcttgataat tttactttac ttccaaaatc tttttgagat aaaccagcat
     1201 cttctcttat ttcttttatt ctatctttta tattttcttc ttggatttgt tcgcacaagt
     1261 tttaccactc cctctttgaa ttttttctta agtatagaat aaatcatttt agtttacaat
     1321 gcaacactta attgaaagat aatggttgca ttgtggaata aaatggtgta ttattaaatt
     1381 ataaattcta ctttgcaaca taattatgaa aggaaggttt ttccatgagg gaagaaaaaa
     1441 ttaaaactat agttaggaaa ataaatttcc tggatgaatt tggtcttgaa attgtaaata
     1501 atataggcga tttgtgcatt aaagaccaaa aaaacaaaaa gaaaagtaat tcttataact
     1561 tagaaaatat catcagtata gataaattag actaatcttg caaagcaaca ttaatgcgta
     1621 ctttgacggc tacgctaaac caattaaaaa aagaaaaata taaaaaggtg gggtaaaaaa
     1681 atggaaatta atagcgtaag agagttaaga gaattggttg aactttttgg agttataaaa
     1741 gcagagagca acaatgttgt ttcttgtaat gaaactgtaa acgagttaag taacaaagag
     1801 ctaataaaag caaatgaaaa caaatttaaa aagccttgga atgatgctct attatatgaa
     1861 ataaatgctt tagatataat aaaaaagcat aagcacagtg atagaaaaga aaaggcatat
     1921 aaaacttatc taggattaga aaatgcagat atagaagaaa tttataaaat tcattatgga
     1981 gataaagaaa attctgaaac tgttgcaagt tgcgaagaaa ttagttcagc aaaaacggat
     2041 acaatatctt gcaatcatga cagtgtttca aaaggtaaag atactagtga ttcagaatgt
     2101 acttgtttta tttgttctaa aaaaatagaa aatcaagaag atgtatttaa aatacctttt
     2161 ttaacacgag attatttgag ttcagcaaaa gaaataaaaa atattgaaat ttgtgagaaa
     2221 tgtttggatg gtaattcgtg gagtattata agaagaaagc agtttaagaa aatgaagaaa
     2281 taaatattta aattagtatc tttacatgtg aaaaaggaga gtgaaaaaat gataaaaaat
     2341 aatgttttaa gttatgaaga aaaaataaaa gtattaaaaa aacatggtta tagtgatttt
     2401 accaaagaat atgttttaaa agaatttgac aaggaacatg cattttacaa atcattttta
     2461 agagcaatag aaaaagaaga tgatggaaaa ggtgtgttaa ttaaaaaaat tggaaaaggt
     2521 cagcatcaat tttcaaaagg ttttataaaa acacacacta tcagtgagtt attggaagaa
     2581 gcaaaacgta ttagaaaaat attagaataa ggcttagaaa tgtctataat ctaaacctta
     2641 tacttaaatt aaaatttacc taatatgtac tctattgcga taggtaggga catatttaaa
     2701 aaacttgaag tggaactttt tattttattc catttagtgt tatctcgtat tttatctaaa
     2761 tattgataac cttttaaaga caactgcatg acctctaaaa cagtatcatc accgtaatta
     2821 acatcgtcaa cgagattatt ttgataaatt aaatttatgt gatgaacaat agttgactta
     2881 tcgtatgtga gattatctag tatagtatca aattgtaata caggcgaaat gggagttgta
     2941 ttagattcaa taagtaataa aatatctctt atacaatctt ggttagtaac catagtatca
     3001 cctccttttg ctttagtata gcacaggaga aatgagatga taataaattt tactgtagca
     3061 gaatgagaag gagcaaagca aatgcaaaag agaattacag aaatgagtat attagaaaaa
     3121 gttgatttaa ttggacagaa acaaaagaaa ctacaagaaa aatataaaaa tctaagtaag
     3181 ggagaattgt tttctattgc ttgtaatgaa gttaaaaaaa tagaagagca ggagggaaaa
     3241 tattttgaat ataggtagtt atacattagt taagaaacaa ctaattgaag aattgaaaga
     3301 agaaattaag caaaaagaag aaaacttaaa agaacgtgag aaatacataa aagaattaaa
     3361 agagaggtta gaatgttttg cgagggatgc gttagaatca gaagagtgca taatagatat
     3421 tgaaaatatt ttgatagaac aaactgtaga attagaagct tataatttat tcatagattg
     3481 cattttaaac aaagatataa gaaaagctat tgcgatttat aacagaacta aaagcatcag
     3541 aattaagcat aaaaatatta attctatatc taagaaaatt gaaaaaataa aacaaataat
     3601 ttccttgtag aaataggagg agtttaatga tggataagtt tgtaacatgc gctagatgtg
     3661 aaagaacaat aaatgtagaa gaaaataatc atgtgaagta tgaagaagaa actttaaatt
     3721 taagttttac gttgtatttc tgtttaggct gcgtagataa attaattgaa caatctaaaa
     3781 tgttggaggg agaaaatgaa taaaattagc gttacacaag cattagagaa atttgacagt
     3841 ttactagata attggaacga ccttccaaat catgtttaca cacttgaata tagaagcaaa
     3901 ttttacgaat ggataaagtt gcttgaaaga aaaggtagtt tacaaaatta taagatagtt
     3961 gaagttttaa atgctgaaag aaatggagaa gaagcgtcgt tttggaattg aagaaatata
     4021 acttgaaaag gacttaaact ttttctagat agaagggagg tatataaata tgaaaatgat
     4081 aaatgttttt aaattatcat caatgtattg tatttgcccc aaatgcggga gcgataaact
     4141 tggagaaggt gaaggaaagt taattgttga tgaacatact tattacaggg aatgtaaatg
     4201 tggttttaat gttcttgtag atgaaagaga agacgaaata taaggaaggt gctggaaatg
     4261 aatagtgtta ttttaattgg aagattaaca aaagacccag aacttaaata tataccgggt
     4321 tctggaacag ctgtatcgac ttttacaata gcagtagata gagattatat taaaaaagat
     4381 ggaactaaag aaactgattt tatacctatt gaggtgatgg ggaagttagc agaaatatgt
     4441 gctaataatc tgactaaagg taggctaata ggggtcgaag ggtctataag agttaatagt
     4501 tatgaaaaag aaggcgagaa gagaacttat acaaaagttc atgctaataa gattaaattt
     4561 ttagactata aaaaagagga taatgaaaaa gaatatatgt ttgaaccgaa aggtttagac
     4621 caacagggat ttcaagctat agatgacccg gatataccat tttaaagtgg gagggataat
     4681 aatgtctaat ataaataaaa aaacagctaa aatttgcggt tggtgtggaa caacagtcta
     4741 ctcttatgta gatggtaaaa ttgcatattg ttctaagaaa tgtaagaaaa aaagagaaaa
     4801 aaatttagaa acagaagggg caaaaaatga aaaaaacaaa aatcgaagaa tttattacta
     4861 aagttaagga aagtatgcaa agtgtagcaa aagaaagcat aaaagactta gaaaatattt
     4921 tgaaagaaat tgaaaccgga gaaacagaag ttaaaatttt atttattgac aaggaaaaaa
     4981 aagttgaaga gattgttgaa tttacacatg acgaatacgt gaaaatgatt attgaaaaaa
     5041 tgatatttga tagtcttaaa ataataaaag aacaacacga aaagatttta aaagagttcg
     5101 aagaaagaga ggtctaaaaa tgaattttaa aatgattgca aatataccaa agtggacagt
     5161 aaaagaacaa tttgaaaaag tgcttgaaga agttttagaa cttaaagaag ctattgaatt
     5221 aaaagataac aaaaaaataa tggaagaagg tttggatgtt attcaagcaa tttttacact
     5281 atttaaagta ttaaagattg ataaagaaat acgcgaaggt ttgaagttgc ataataaaaa
     5341 actaagaaaa agaaagtgga aactcgaaaa aataaattag cagaaggggg agttaaaatg
     5401 agtatatgta gaaagtgttt gtacggagac tatttagatg aactagtagt aggcgaatgt
     5461 attttatgtg gtcaagaatt tttttctata aaaactccgg ttgggaaaat gtgtcctagc
     5521 tgttcagaaa tgtttaaggg gaattgttct caatgtgcaa aaccaatcgg aaatgaaaaa
     5581 aagtcattta aaaataaatt aaagtaaata ggcaatataa aacataattt gattgatttt
     5641 taaattaaaa tagataatat actttataaa tatagatttt atttaaactt aaaaaaatga
     5701 agtcttatga caaaaaaaca aaataaaaat ccagaatatt ttgaataata tgcagtagtt
     5761 ggaaatgcta caaaatacct aactagtccc aaaagctaaa tttaaggatt agttaggtat
     5821 ttataacaaa aagtacaaga ggtgtaaaaa tgaaaataaa aaaagagtat tttgacaaag
     5881 tggaaaatgc attaaaaatg ttaggagata aatatagaaa gttaagagta ttaaaaaaag
     5941 aaatagcaat tcttaaacac aaagaaaact atagagaaat taattatgaa gaattagggt
     6001 ttaaagtaca aaaaagtgta aaaggtatag atgacatggt tgtaacaata gaggatgcta
     6061 tctacaacaa agaaactgaa attgaaatta tagagcgaaa gctagagttt tataatattt
     6121 atttaaaaga gctatcagag atagaacaaa aaattataga actagtatac ttttatagct
     6181 ggaatgggaa aatgcctatt acaaaaatgg cgatggaatt aaattatgat agaactagtc
     6241 tttataacaa aaaagctatt gctattaata aaatagcttt aatgatatat ggtgatgaag
     6301 ctttagaata aacattattt ttacagaaaa aagactattt ttatacttcg tttctaaaga
     6361 aagcatgtta gaattgtatc atagaaaaaa gtgtacattg acaactgaat atcccccgaa
     6421 acctaaagtc taaacttgaa gctcgaaagt ttaggctttt ttattgctaa aaaaggaagg
     6481 gggtgagtaa atgaattttg tagaacctat cagaaattta gagaagctag aaagcatatg
     6541 cgcttattta gaagaaacta acatgagaaa caatgtactc ttcagtatgg gcatatatac
     6601 aggacttaga gtaggggaca tattaaagct tagaataaaa gatgttcatg acaaacggtt
     6661 tataactctt aaagaaagta agacgggtaa gactaagcct atcgaggtta atcctatttt
     6721 gagaagaata ctaaaagaat atacaaaaga taaaaatcaa aatgaatttt taattaagag
     6781 tagagagcag accaataaag ctataagcag agtcatggct tataagataa tacgagaagt
     6841 aggcgaaatg tttggtatag ataatctagg cacacataca atgcgtaaaa cttttggtta
     6901 tcattactat aaaagaacac atgatgttgt aacattgcag aagcttttta atcatagttc
     6961 agctacgata accttgcggt atattggaat tgaacaggat gatttaaaca aagcatatag
     7021 gaatattaaa tacttttagc ttaagagttt aacataaaaa ggtcacgtta aactggataa
     7081 aatatagtct aataataaag tcttgaatgt attgttaata ctaaagtgta aggctgtttg
     7141 ataatactta aatgagttta acagaatata tcttatgtta aactcaacta ggaaattaaa
     7201 ggagtatcac tatgaataag tatggtaagt ttaaatgtaa taattgcgga aagaaagtta
     7261 atgtaaataa tagagattta aagactaaag ttattgataa tactactgtt acatacttca
     7321 tgtgtcgcag atgctttgag aagtttgttg tatcatgtga ggatgattat attaaacata
     7381 agagagaaga atataagaag cttaaagatg atgaagtcaa gctattgcaa gacatgaaag
     7441 agtatagcga cggtctagga gagctgtata ttaatgagtt ataagcacat gacactagat
     7501 agattaaaag aattaatttt aattgataga cttgatatat tctatagaag tacagactgg
     7561 cgtaaattaa gaaaaaaagc acttgaaaga gataataatg aatgtcagat ttgtaaagaa
     7621 aaaaagaaag tatctaaggc ggaatgtgta catcatatca aagaggtaaa agagtatcca
     7681 ggtgaagctt tgaagcttaa taacctaaca agcttgtgca acctttgtca caacgaaatt
     7741 cacgaaaaaa tactaaaaat taatcaagaa aaaaagaaaa aatttttcag tgaagagcga
     7801 tggtagatag cccccctatt gaaaaaactg gctttcaagg caaaattttg tgaaccgagg
     7861 taggtacatg gctccgcaag gagacgtcaa tttaacaaaa ggtgtggggg gtgggggtct
     7921 tgcaaccaaa attatggttg cgggtgcaga aaaaaacata aaaatgaggt ggtgaaaatg
     7981 gatgataatg aggaattaga aattaggcga gacgtacaga atgactacgt tttaggcatg
     8041 acttacaaag aaatgtcagc caagtataac atacccgaaa acactttgaa aagttggaga
     8101 aaaagagggg gttggactcg caactgcacc ccaaaaaagg gttgcgtgaa aaatgggttg
     8161 caagagtcgg gaaataattt aaaaaactct ataagaaaag atttattaag acaaataaaa
     8221 gagaataaca tgacagaaga atacttcaaa gacttagttg aagattattt aaaaatgtgg
     8281 gatataaaaa atgaattaat agaagatgta aaaactagag gtgttcaagt caaatataaa
     8341 aatggtcaaa atcaatgggg ctataaaaaa aacgatagtg tatcagagct tattaagtat
     8401 aacgctcaaa tgttaagttt acttgataaa ctaggtataa aagcgacacc aaaagttttg
     8461 ggtgatgatg atattgaatt ataagtacaa taaatacata gatgaatatt tcaacttagt
     8521 tgataaaggc gaaattgttc tatgtaaaga aatggaactt gcagttaaga aaataaaaaa
     8581 agatttaaaa aaacctaata tctatatcga ccatgaaaaa gttgaaaaag ctatcgaata
     8641 catggaaaag tatttctata aaatgtatgc ttgggaaaaa tttgttgttg ctttagtagt
     8701 tggctgcttt gaaggcgacg aacttttata tgatgaaatt tttatcatga tgggcagggg
     8761 aaatggaaaa aatggtttta tatctcaatt agctaattat ttgcaaacac acttacacgg
     8821 tgtaaaaaat tatggtattg atattgttgc aatgtcagaa gaacaagcaa aaacaagttt
     8881 tgatgatgtt tataacatgt tatctgaaca tcctgctata tgcaaaaagt tttttaacag
     8941 aactaaagaa gtaataacat ttaaaaaaac taacagctat ttaaagttcc gcacaaataa
     9001 tgctaagtca aaggatggat taagacccgg ctgcatcatt tttgatgagg ttcatgcata
     9061 cgaaaattat gataatataa aagtttttac ctctgcgctt ggaaaagtaa aaaaccctag
     9121 gattttttac attacaactg atggaaatgt aagaggtggg gtattagacg atttcaaaga
     9181 ggaatcaaaa caaattttaa atgaagaaat taaaaactct aaaatgctgc cacttatttt
     9241 taagcttgat agtatagaag aaatggaaaa tattgattta ctggaaaaag caaacccgag
     9301 cataaagtat aattcagact taaggacaca aattttaaaa gacattgaca aagctaaaaa
     9361 tagaccgcag atgatgatag aattactaac taaaagattt aatttgccag cgcaaaattt
     9421 agcgactgtt gttgctgaat gggatgacat agttgcaaca aacgaagaat taccagacct
     9481 aaaaggcttt tcgtgcattg gaggattaga tttttctagt ataagagatt ttacaagcgt
     9541 ggtattgtta tttaaaaaag ataaaaaacg atatatcatg catcatactt ttatatgtta
     9601 taagtcttta gaaataacaa attttaaatt tgatattgaa ttagcaaagc aaaaaggtct
     9661 ttgtacaata atttatgatg aaacgataaa agcagagtat attgctgatt ggttcattga
     9721 aaaagcggag gattataata tattaaaaat ctgctgtgac tcatatagag ctgcacatgt
     9781 aaaagaagaa tttgctaaca aaggtttacc aatcgaagag gttagaaatg gttcaataac
     9841 tcatgcgaaa atagcccctc ttgtagaaca aatcttcgca gagagaacaa ttaaatgggg
     9901 cgacgacatg atgatgcgtt ggtatactaa taatgtttat gtagatacag acaaaaaagg
     9961 aaataaaact tttttaaaga tagagccaat caaaaggaaa acggatggct tttttgcatt
    10021 tttacatgct ttatcaaaag atgatgaact gatgcaagaa tcaacaatta aattttatga
    10081 ttgttataca tattaaaaat aatgaggtgg tgaattgaat tttaaaaatt ttataactaa
    10141 ttttttattt aaagataaaa tgtctggagc agatggagag tattttaaaa aactagaagc
    10201 tacgatattt tataaagaat ttgcgttaag gtcatgtatt tctattattg caaatgcttt
    10261 agttttaagt gagtttcaga catttaaaaa tggaaaatct attaaagaaa aaaattatta
    10321 cttgtttaat atagaaccta atcaaaacca aaacgcaaca gaattttggc aagaagtaat
    10381 tacaagactt gtgtatgaca atgaatgtct agttatacaa gaaaacgaac agcttttcgt
    10441 agctgaaagt tttagtgtag ataagtatgt tttttatgaa gatatataca aagatgttac
    10501 aattagaaac tataaattag atagaagttt tagagagtca gacgttttat atttcaaatt
    10561 aaatgttgaa agtataaaaa ctgtaataga ttatctttat aatgattata aagatttatt
    10621 aagtagcgct atgaaaggtt ataaaaaaaa taatagcgaa aagggcgtac ttgaaataga
    10681 cacaaattac ccgcagacga aagaagcaca agaacgactt aatgatttga tgggtaataa
    10741 gtttaaactt tattttgaaa gtgataatgc tgttttaccg ctttcgaatg gattaaaata
    10801 tacagaaaat acaaaagctt caagtataaa agatagcaga gatataagag cgattattga
    10861 tgatgttatg gactttgtat gcgctgcttt tcatattcct gctgggcttg taaaaggtaa
    10921 tatttctggc gttgaaggta taacagataa ttttttaaat ttttctatca atccaatcgc
    10981 tcgacttata acaactgaaa taactagaaa aatgtatagc agagataatt tttttgaaaa
    11041 gagttatgta aaagtagata cacaaaaaat tgctaacatg ggacttgaaa aaatatcaaa
    11101 agcaagtgac ttgctattta gaataggtgt aaattctata aatgacaatt tagaaatgct
    11161 tggtcgagaa aaaataaatg agtcttgggc tgatgaacat tatgtaacta aaaactatca
    11221 gtcgatttta aatccggatt tgaaaggagg ggctaacaat ggaaatggag aaaagagcgg
    11281 tatcgctgga aataagggac agtaatttag aaagtcgtaa gataagtggt tatgctgcta
    11341 tttttaatga tgattatact aaattgcaag acagatgggg cgatactttt tacgaaaaga
    11401 tttcaagagg tgcattttta aaaactttag cagataacac tagggataag tttatgctta
    11461 taaatcatga ctggaataaa gttataggta gaactaactc aaatctaatt ttagaagaag
    11521 atgaacgtgg gttaaggttt gaactagata taccagctac gacggatggg aatgatttgc
    11581 ttgaaaatgt aagacttgga ctaattaaag gatgttcttt tggttttaat attgtaaatt
    11641 caaaaactcg ttttgatgat gattggacat attacagaga tataacagaa gttgaattat
    11701 ttgaaattac agcaacccct attcctgctt ataatgatac tgaaataaat tgtagaagtg
    11761 atatatctat aaaagaactt agagaatctc aaaaagaaga agcaaaacaa aatgacaata
    11821 aagataatat agaaaaaagg aatgtcgatt tagtatcggc tttttttaat gcatttaatc
    11881 gaggaggaaa ataaaaaatg gcaattaaaa atttagatga ggcaactaat gttgaactaa
    11941 gaacaaattt aatggaagca ataaagagta atgacgaaga aaaaataaca actgcgtttt
    12001 tgaggatggc ggaagatata caaagtaatt tactaaaaga agcacgttct attgctaaca
    12061 cagaatcaat tgacagggcg atacttgaca agcgaggtat gccacaatta acaagcgagg
    12121 aaagagcata ttatagccaa gtgatagaaa aaagaggatt tactgattta gagataacta
    12181 tgccgcgcac tatatttgat agagtgtttg atgacttaga acaaaaccac cccctactta
    12241 gtgcaataac ttttgaaaat acgacaggcg ttacggagtg ggtaataaga aaaacgggaa
    12301 cggaggcagc ttggtggggg caattaactg accctattaa aaaagagtta gaaggtggat
    12361 ttgcaaaaat taatactgtt gcttataaat tatcttctta tcttccagtt gcaaaatcta
    12421 tgcttgacct aggtgctgaa tggttagaca gatatgtaag agtagttttg actgaatcta
    12481 tatcattggg gcttgaaatg ggaatagtag caggaacagg aaaagaccaa cctattggga
    12541 tgatgaagga cttaaaaggc tctgttgttg aaggtgttta tccagataaa accgcaaaac
    12601 cattagctga ttttaaacca aatacattag gaactgaaat catggcacca cttacaaatg
    12661 atggtaaaag gacagtcgca agcgttataa tgcttgtaaa tccggttgat tattgggcta
    12721 aaatcttcgg tgcaacgact atgctaactt caaatggcac ttatgtatat ggagttctgc
    12781 ctataccagg aaatataatt cagactgttg ctgttccaaa aaataaatta atcgtaggag
    12841 ttgctaaaga ttattttatg ggaattgggt cagctggtaa aatagagtat tcagatgaat
    12901 ataagttctt agaagatgta agagtctatc ttgctaagca gtacgcaact ggaacaccaa
    12961 aagataattt ttctttttta gtatttgata tagaaaactt agacacaact ttagcaacag
    13021 aaattaattc aaacacaaaa acgtcagcta ctagagcaaa ataggtgaaa aatatggaaa
    13081 atgaaaatat taaaaatata gttgaagaag taaaggaata tttaaatata acttggatag
    13141 aagaagatgc aaaaatagaa aaaatggttg taagagggat taattactta gaaaatgaaa
    13201 tagccggaat agcattagat tttaaagata attttaatag agagttgtta tttaactatt
    13261 gcagatatgt aagaaacaat gctattgaat atttcgaaga aaattttagt aaagagcttt
    13321 ttagacttca aattaaaagc gcagctaatg aggtaacaaa gatatgaaaa aaataaaatt
    13381 tgataatttc aatgatggta ttattgaatt tggagaatat aaagaaagct acgatataga
    13441 aggtaatgca ctagatgaaa aaaagtttat tgtaaatggt aaactctttt attctaatga
    13501 atatataaga gagcaggaca gacttaaatt tgataataca gggttaaaag tatctattaa
    13561 attaaaagtt ccttatatga aattaattaa aacaagtgat gttataaaac taaataatga
    13621 attttacagc atagtaaagc tagatattag taatgacaaa actagcatat atttatattt
    13681 atctgaatta gttgacgtac tagataagca tatttctatt tttattaaag aaagaaaaaa
    13741 tgttcttgaa gatgtagaaa tgaaatttta taaaaaggtt tgggcttgtg ttgaagattt
    13801 aaacagcaaa gaattgatag aaaataattc aattaaaact tctacaaata aaaagtttaa
    13861 aattagatat attgaagaat tagatttaag tataaaacaa aatgctataa ctaattttgt
    13921 tattaaatac aaagataaat tttacaatat aactcaaatc ttaaatttag aagaagaaaa
    13981 taaaatactt gaaataacag cagagtctaa gtaaaaaatt aggtggtagt atgcattcaa
    14041 aaatagttac tatacttgaa aaattaaata taggaattgg ctttcaagaa tatgacaatt
    14101 tttcaaatga tgaagaatat ataatatttt ttatagaaaa tgaatatgat gcaaattttt
    14161 ctgataatga aaataaaagt attgtatatt caataaagat agagtattgg tataagagct
    14221 taaagaatat aaacaaatat attagtataa aagatatgtt taaaaaagaa gattttatct
    14281 ttttaaattc tagtgatttt atagaaaatg aatattattg taaagaatta aaattcaaat
    14341 atgaggaagt tatttaaatg agtgtagaga taacaacaga aggttttgac gctattttat
    14401 ctaaaataga gagcatgggc aaatcgggcg ataaacttct aaatgaagct gtaaaagctg
    14461 gcggcaatgt tattttacaa gatgcattac caagggtcag taaaagaagt ggaaagttaa
    14521 aagatggttt aaaagtaagt ggagttaaga aaaaaggtgg tactaagtat gttttagttg
    14581 gtattacgaa agaggataat tcaaaaattt tttatggaaa gtttttagaa tttggagcat
    14641 ctgcgcataa aataccaatt aaaaaaggta agaaaaaagg aagggtagta aatcatccgg
    14701 gtgttagtcc taaaccgttt ttagcacccg catacgagtc aaaaaaagat gaagctaaaa
    14761 atgtaatgaa agaaatatta aaaagaggat tggggttata atgattaata taaatgattt
    14821 agtaatagaa acattaaaac ctttaaaaat tcctgtttca tttcaaaggt ttgatggaga
    14881 agaaaaaaca tatataactt tttttagtta tttagaacaa aaccgctatg ctgatgatga
    14941 agtagtaggc acagaacatt atatacaaat agatttgttt agtaagaata aaatgagtta
    15001 tataaataaa gaaattgaaa gacttcttaa aaaaaataat tttataaaaa gaagtataca
    15061 cgaaataaaa gaatctgatt atagttacca tactattttt agattcttat tttttgcgaa
    15121 aaacgaggag gattaagaaa tggctattat aggattaaga aactatagac ttgttaaatt
    15181 gcttgttgat acagaaagcg aacttgaata tgacactaaa ataatgaaat taacaggtgc
    15241 taagaatata aaaatagcac caaaggttga tagtgcggaa aattatggtg atgaccaact
    15301 tttagaaact gcttcagcaa tgggagctat agaagtagaa tttgaggttg ctagtttaac
    15361 attagaagaa aaagctttta ttttaggtta caaatacaaa gatggcgttt tggttgaaga
    15421 taaagatttt aatccgccaa acattgcgct tggatttgaa tctcctaaat cgcaaggtgg
    15481 aaatagaatg gtttggttaa ctaaaggcgt atgtgaacca cttgaagaag aagcaaaaac
    15541 aaaagaagat aaagttgaat ttcaatctca aaaaattaag cttaagttta tgccacgtat
    15601 aaatgatggt agacataaaa taacagcaga tacagatgtt gaaaactcac caactgcgga
    15661 agaatttttt gcaacagctt ttttaaaaac agcagcaaag ccaacagcac cagcaaaaac
    15721 aaatttaaat aaataaggag aaaattaaaa atggaaataa aattaactat aaatgaagaa
    15781 gaaaaaatat tcaaagcacc tcctattgca cttagaaaat tagataaagt ttttacacta
    15841 accgataaaa tcgaagatgg tcttaactct acagaattat tccgcgaatt gcttgatttt
    15901 acagttgata tatacgggga acaattttca aaagatgagt tattagatgg tttttatcca
    15961 gctggtgatt ttataaataa agcgttagaa gatttatcaa aagtaagtgg aggtttcgaa
    16021 gaaaaagtaa aaaactaggt aatggagaag atacagaaaa taattctaat aaagaaaata
    16081 ggtatctatc tccacgtgat tttataaaag atttatatag catgttttta tttgaaaaaa
    16141 attggagcat gacggacata gacaacatgg atatatttta ttatttagat atacttgtgt
    16201 atatgaaaga gaataaaaaa gataataata atccaaatga aaatgatgtt tatattgacc
    16261 agataagctg gttataagga tgtgagtgta tgtgtaagta ctgtgaagtt aaaattaata
    16321 cagaaccgtt tagcatgtat gatacagttg taagaggtga attattaact aacgactccg
    16381 acatagatat gtatatagaa cttaaaaacg gaaagcattt tctaacagga gcaagttacg
    16441 actatttagg aatcagtagt aaggaaacta ttaaatattg tccattttgc ggaagaaaat
    16501 taatttaata taagttttat ataaaataaa ccaagataaa aatcttggtt tatttttttg
    16561 caagtgaggt gagagaatgg cggaagatgt aggtgaatta gttgttcggg tcgctatgga
    16621 aaatagttca tttcagcaag gtgttaataa tctaaatagg caaatgaagt taataagaag
    16681 cgagtttaaa aattctggcg ctggagtgaa aaattttgga acaagtcttg atggtttgaa
    16741 atctaagcaa caaatgttat ctagtactat acagcagcaa actaaagtag ttgaagcata
    16801 taaaaataaa ctaaatgaaa gtaaaacaac tttaagcaac acagcacaaa agcaagttga
    16861 acttaaagaa aaagttaatc aagctaagag tgcttacgaa cagagcaaag cgacgttagg
    16921 tgaaaatgca gaagaaacaa aaagattaaa atctgaactt gatagtttag aacaagaata
    16981 tgctaaaaat gaagaaaaaa taaggtctaa ctcggcagcg gttgataatt ggtctattcg
    17041 agttaataat gcagagtcga gactttctga aatgcgttca gaactagatg acacaacaga
    17101 aagaataaat cagcaggaaa ataaatggaa tcagttggca actaaaatga ctgaaatagg
    17161 taataaattc agctcggttg gaaaacaaat gcaagatgta ggtaaaaaaa tgactatgag
    17221 tattactgct cctattctag cagtcggagc agcggctagt aaacttggaa tggattttga
    17281 agcatctatg tcaaatgtac aaggattgag tggggcaaca gctgacgaaa tggttcaact
    17341 tgaaaaagca gctagagaag caggggcttc tacatcaaaa acagctaaag acgcagcgga
    17401 tgcgcttgga tatatggctt tggctggatg ggatgcaaaa acatcaatgg aggctttaat
    17461 gcctgttttg cgattgtcgg aagctggaaa ccttgatttg gcaagaacct cggatttagt
    17521 aaccgactct atgtcatcac ttggacttag tgtaaaagag ttaccaactt acttagacca
    17581 agttgctaaa actgccgcaa gttcaaacac taacattgac gcacttatgg aagctatgat
    17641 tgtgtctgga ggtactttta aaaatttaaa cgtacctctt tcggaagcta atgcactgct
    17701 tggaatactt gcaaacagag gactaaaagg cagcgaggca ggaaactctc taaattcaat
    17761 tatgataaat ttgacaagtg gagcgggtca agctggtgta gctatgaaag aactaggatt
    17821 aagtgctttt gattccaatg gtaaattcaa aggtatggct aatgttttga tggaacttaa
    17881 agaaaaaaca aaagacatga cagaagaaca acgaacaatg tatctatcca tgataggcgg
    17941 aaaaacacaa atatctactt tgcaagcctt gctatctgga gttggagaag agtattcaga
    18001 actcgaaaaa aaagttggaa atagtacagg tgcattagat aaaatggcta agactatgca
    18061 aaataataat aaaggttcta taacggcttt aatatcagct gtacaggaac taggacttaa
    18121 aatatataat gtactaaaac cttctatagc gcaagcggtt agctggtttc aaaatcttac
    18181 aaataaatta aatgaaatga agcctagcac ggtagaaact atagttaaaa tagcaggatt
    18241 agcagcagcg cttggacctg ttcttttaat tggtggaaaa atagttagta tgattggcgg
    18301 agctataggg gcttttggta ctttttcagc agcaatggca gtcgtaacga caggagcagc
    18361 cgcagcaact ccagctgttg gtgctttagc tgcaatttta ggtgcattat caagccccgc
    18421 agctgtagct atagctggaa ttactgcgct aggcatatcg gttgcaacag tcgctaaaga
    18481 catgtcaaag gatgctatag agccaattag ccgttttggt aaaagtgtat cagaatctac
    18541 aaaagaagct gtaggcgctt ttatggattt agaagaaaaa acgacgatat ctttaaatca
    18601 attaatgtgg agtggtgaga ctgtttcaga gaaaatgaaa caatcaatag tatctaattt
    18661 tacagaaatg tcaaatcaaa tcattgctaa acttcaagag agtaaagagc aaggtattca
    18721 gtctttgcaa gaaatgtttg caacttctaa aaatttaagt gacaaagaaa aagaagagtt
    18781 aataaaaaat actgaagaag cgtattcaag caaagaagaa aagataaaaa agagcaatga
    18841 aaaagtaaat cagataatga ctaaagctag tcaagaacac agaacattaa caaaagaaga
    18901 atcagcagag ataaatcaaa taaaaacaga tatgctaaat accgcagttg ttacaatgag
    18961 taaaagcgaa gcagagcaag ctgcaataat ggaaagaatg aaagcaaatc atgttgattt
    19021 gtcagctaaa gaagctgcgg aagtagttaa aaactcaata aagaaaaaag acgaaagtat
    19081 aaaagcagct aatgaagaat ataacgaaag attaaaaata gccgcacagc ttagagcaga
    19141 gggtggagca gaaaatgaaa agttagctga taaagtagta gaagaagcaa caagacaaaa
    19201 agatgaatca ataaataaag ctaaagaaat gcatcaagga gttgttgcag aagcacagaa
    19261 acaagcagaa aaccaagcga gtaaagtcga ctggacaaca ggagaaataa aatctaagtg
    19321 gcaagtttta aatgatacgg taaaaggtaa gatgcaagaa tgggacgaca tggcgggcaa
    19381 ctgggtagaa ggcttgaaag aaaaaatatc tactggatgg gctaatttaa aggaaaatac
    19441 agctattttg tgggataata taaagcttac tgtaacaact aaatggacag agataaaaga
    19501 gtctatagcc tttaaaatag aagaaataaa acaaagtatt agcgaaaaat gggagtctat
    19561 aaaattattc tttacaacaa cgtgggaaaa tataaaaatg attttcggga acgcttggga
    19621 tgctataaaa caacaagttg aagaaaaatt tgcgcctttt gttgaaaggt taaaaattat
    19681 atttgatggt ataaaagagt tttttagaag cacttgggaa gttataaaaa atatagtact
    19741 tggtgctgtg ttattaattt tagatttagt aacagggaat tttgataaac taaaaactga
    19801 cgcaatacaa atttgggaaa acataaaaca aagcttatcg gatgcgtggg aatctataaa
    19861 agaagtattt aacaatgcgt tgactgcaat aagcgattta ctttctaaca tgtgggaagg
    19921 tatgaaaagt actgcatcaa gcgtatggga atctataaca caaactttaa gcagtatatg
    19981 ggaaaatata aagtcaacat gttctaatgc ttgggaaggg ctaaaaacaa tttgctcaaa
    20041 tacttggaca aatataaaaa caacccttgt aacctcatgg gaaaacatga aaacagctgt
    20101 tagtactaaa ttgactgaaa ttaaaaataa tattgtaact gtttggaata gtgttattac
    20161 tttttttaaa acacttccag ccaaattaaa acaagccgct attgatatgt ttacaagact
    20221 aaaggaaggt atagactcga aaaaacaaga tgctgttaat gcatctcaaa aagtcgggac
    20281 tgatgttgta aacaaaataa aagagttccc aagcaagttc ctgcaagttg gtaaagattt
    20341 tgtaagcggc ttagcgaatg gtatatccgg ctttgcttat aaagtagtag acgaagctaa
    20401 aaaattaggg caaaaggctg ctgatgcggt tagaaaagtg ttaggaatac attctccatc
    20461 tcgtgttatg gctgagattg gtaaattcgt tgatgaaggt ttagcacaag ggattgctaa
    20521 taatagcgac tcggtcaaaa aagcaactga aaagataaca aagattatag aagaagaaac
    20581 aaagaaagct acaaaagcat gcgaagaaga tataaaacta tttaataaac aaatagacga
    20641 attatctaaa caagaaaaag cagcgcttaa aaaagtaaaa ggtgacgcta aagacgcatt
    20701 gaaagaagaa tatgcagcta aaaaagaaaa aataaaagaa gcgatagcac taagaaaaga
    20761 acaaaaagaa aaagaagttg aacagctaaa agagatagca aattcagcta aagaacagtt
    20821 aaataaagag ttacaagaca gacaagagtt tgtaaaaaaa gttgatgact taacaaaagc
    20881 aatagttgat gcgctgaaag aaaaatacaa acaagaatac gaagcacagc aagcgagtat
    20941 aaaaaaagag ttagacgcac tagataaatg gaaggaagaa agtatagata gaattaatag
    21001 tgtctatgat gcgaaaatta aagctattga caacgaatta gaagcttttg aaaaagctga
    21061 aaaggaaaaa gatagacttg aacaagacaa agaagaatta aacaaaatag aagaaattaa
    21121 aacagctata aagtttgaac atgatgatac taacaaagaa cagttgcaaa aagaactaga
    21181 gaaggtttta gctgaaagaa aaaaaagaat agagcaacaa gaaatagaag ataaaaaaga
    21241 agctttaaaa aagagaaaag aagaattaga agaaaagaaa aaagacgaaa tagaaaatat
    21301 aaatcaaatc tatgaaagcg aaaaggaata ttataataaa agacttgaag acgctaaaaa
    21361 gttctatgat gaaagaataa aagaatcaaa acttcaagca gaagctgaaa aattgataat
    21421 ggataaaaat caaaaagaaa tagttgcgtt attaaatagt tattcagatg catataaaaa
    21481 tgcaggtcaa actctaggtg aaaaattact tgaaggattt aagcctgcca taaacgaaat
    21541 taaaaatcta attgatagta ttacaagaga aataaataat gctagaaatg aagcattgag
    21601 tttaaatagt gatattagaa aaggaaattc agcagctaat tcaaattcgg gaagaagaga
    21661 agcaacttat aataataatt caagaacagc gaattataat gtaaacgtta atagtacaga
    21721 ctcaaacaca gcaagagaaa tcgaaagaac aataagaagt ctagcattta gtttataaaa
    21781 aaatagttta taaaaaaggg gtgtgaaact tgcaaaaatt aatatgtaga aactcgaaag
    21841 ggcaagaagt taaattagga aactcacgcc cttttttgtt agaaaaaata gaaaacggag
    21901 caaatactag tgctaatatt tcagtctcga acaatctagg tgatggtgta agtatagatg
    21961 atataagcat aaaagagaga ttacttccta tttcagcagc tatttatgca aaaaataaag
    22021 aagatttaga attaaaacgt gcatatttaa cctctttgtt taatcctaaa ttaggagaaa
    22081 tggaatttat atatacaaat aacgcattaa ctaaacgtgt caaaggagtt gtgcaagaca
    22141 taacatttca aacaccagtt ggattgatgc aaaagtttct tatacagctc ttaactccaa
    22201 gcccattttg gatggatgag tttgttttaa aagaagaagt cgccttatgg gttggtgact
    22261 tcgaatttac tttagaaata agtaatgaag gaatagaaat gggtcatagg gtaagtaatt
    22321 taatttgtaa tgtagtgaat aacggagacg ttgaatgtgg catgaaaata caatttaaag
    22381 cacttgcaac agttgataat cctagcctat ttaatgtaaa cacaagagaa tatattaaga
    22441 taaacagaac ccttgaagct ggtgacttat tagaaataac aacagaattt gcaaataaaa
    22501 gaatagagtt agtaaaatca aactatgaaa gaataaatgt atttaattgg attgacttgg
    22561 atagcgaatt tttacaactt gaagttggag acaatttatt tagatatgac gcagacgtag
    22621 gaattgataa tttagaaatg tctatatatt ataatccact ttatttgggg gtgtaatatg
    22681 cagcagagca taagaatact agataaaaat ataaatttaa tagctgaaat agataattac
    22741 gaagaattac agattattaa aaaattccac aaagtaggag agtttagttt aaaaataaat
    22801 gctaataaaa atcatgtaga taaattagtt aaaaataata taattctact tggtaaaaat
    22861 tataataaag tttgtttgat acttcatcga gagttcatgt acaccgaaac aggagaaaaa
    22921 agcgacattt tatctgttaa aggcgtggat ttaaaaggct tgttaaatag aaggctcatc
    22981 atacccgaca ctggagaagc tttcgaaagt cacgaaggga cacaagaaga aattataaaa
    23041 gcttttgtta ataataactg cgtagactct tcaaatccaa aacgtgtaat tgataatctt
    23101 atcatttcag aaaacaaaaa tcttggaagt gctgatatgt ggcgaagttc ttacgaaaat
    23161 ttaagtgata aaattcaaga aatatcagaa ttttgtgggc ttggttggga ggtagtgttg
    23221 gatgctaata aaaagaaatt tatttttgac gtaattactg gtaaagattt gactattaat
    23281 caaacagaaa acccgccggt tatttttaga agtgatttta ataacataag agctagacac
    23341 tttacagaaa gtataattaa ctctaaaaat gttgtgtatg ctggagcaag agaagacgcg
    23401 acaaaactgg taatttcaac tggtgaggtt gaaggttttg agagaaacga agtctttgca
    23461 gatgtaagtg aaaatactat aagcatacta caaaaagaag gagaaattaa attaaaagaa
    23521 tatgaagagt taaaaagttt tgaattagaa atagacccta aaaatacttt tatgtatgaa
    23581 aaagactaca aactagggga tattgttaca gttcaagata gaaaattgaa agtaacaatg
    23641 gatactagaa ttgtagaagt acaagaaagc tatagtaaaa atgggatgaa attaaaaatt
    23701 acgtttggga gcagcatacc aaccttattt tcaaaaataa aaaggatggt gaaataatgg
    23761 aaaaaagttt tgtatttaat agtgtaaatg gcgataggag atacaaggca gaggacttta
    23821 gagaatattt tgctagtttt ataggtaatg gtgtattccc taatccaagt agcaatttgc
    23881 aagttgtaga taataataat aataatatga ctataacagt aaaaaaaggc aagggctgga
    23941 ttaacggagc tatctatata aacacagacg atttagtaat taatatagac cccgcagatg
    24001 gaattttaaa tagaatagac agagtagttt taagatttga tactttaaat agaaatatta
    24061 aattagctgt aaaaaaaagt gcttttaata gttccccagc tgcaacagaa ttacaacgtg
    24121 atgcagatgc gtacgaactt ggattagctg atatttatat cagagctgga gcaataagta
    24181 ttacacaaag ttctataaca gatttaagat tagataaaaa tttgtgtgga attgtaaaag
    24241 gtacgataga agaaatagac acaacaacat tacttgcaca actaagtact tggaaagatg
    24301 aagaaataag taatttcaat gattggcggg aaaatcaaga gaataaacaa gaagattggt
    24361 ataacactac aacaacaaat tttgtatcag agtttaacat ttggtttgaa agtataaaag
    24421 atattttgga tgaggatgca gctggaaact tattaaatga aataaacaaa gtaaaagaag
    24481 agttagcaaa aatagaaaca acagcagaga aaacaagtta taataatgca acaagtaatc
    24541 ttactgctac aaatgttcaa ggggcaatag atgaaattgt tgcaaaaata gaaaatttta
    24601 acgagattaa tatatccata caaaacgata tgttacctat ttaagagagg agagtgaaaa
    24661 atggctatag tttatgaatt taattataca ggtgctgaac aaagtgtagt gttgccacct
    24721 ggtaaatata agtttgaatg ttttggtgct tgtggtggta attattatga ttttgtacag
    24781 tgcgcaaaag gtgcctatac tgctggttct ttaatattga aagaaaatac tacattacat
    24841 gtttacgttg ggcaaagtgg ttattgtaaa ggtgttaatg gtattgagac ttgtagaagt
    24901 ggttttaatg gtgcgggtgg tataaccact tataaaagta cttctgatgg ttattatagt
    24961 cttgcaggtg gtggagctac tgatattaga cttattggtg gtaactggga taatttacaa
    25021 agtttgctat ctcgcataat tgttgcaggt ggtggtggtg gtggaagcgg aaattcacat
    25081 gatagtattg gtcatggtgg tggtacaaaa ggtaaagatg gtatttctat agcaaataaa
    25141 tattttgcag gcggtggaag ccaatttcaa ggcggtttaa cttttaatag tctttataat
    25201 ggttcttttg gtgtaagcgg tgctggagat ggcattagtg gtgttggtgg cggtggtggt
    25261 tggtattgtg gtgcaggtag tttttatgct gaatttggtg gtggtggaag tggatatatt
    25321 ctaacaaaag atagttataa gccagcaaat tatagtccat cttctaaata ttattttagc
    25381 gatataaata gcgttgtagg tggaaatact acgaaacaag atggttatgc taaaataaca
    25441 ttactacaag cattgccatt tttaactata tcctcatata actcaaccac agcaacattt
    25501 aaagctgacc acacagaccc aacattgtta actaaaatag aatattttat agatgatgta
    25561 ctaaaagaaa ctataacaac agatttaacc cttgaaaaaa caattaacta tacattagaa
    25621 gataatgcac tacacacact taaaatagtt gttacagaca gtgctaatgc tacagcagaa
    25681 aaagttgtaa gtataagcaa aggaattgca cctcttcctg ctggttctac aacagatgaa
    25741 gttacaagta aatggataga aattaaagat gcatttaaaa gtggcaaaac aagtattata
    25801 aacactttag cattaaaaaa tatagaagca agtttaaaca atacattagt agagttatca
    25861 gagaaaatta aaacttcttt tgatagttcg gacgctagtg tgcaggattt gatgaaccag
    25921 ctaacacaag ctaataatac tataagtcag ttaaatacaa gatataaagt tgcgagtgga
    25981 attacttatc aactcaataa cccaagttta tctgccaatt tttataatgg tggttataca
    26041 actactcaag accattggat taatgttagc aatcttggtt ttgttcctca tatttttata
    26101 gctgagtgcg attttacaaa agatggttat ttaactaaga gtttagtttt tgccagttat
    26161 aatgttttta gtaaagatta tgtaatttct tcatatttta gacgtcaaac aaattcaact
    26221 ttttactcac atggcaacat ttataatctt aatgaaaaag atgtttatgt taatggcaga
    26281 ggtgttcaac ttcctgcttt taataattac gattttgcat ataagtggca agctataaaa
    26341 tttgtataaa tggggtgata aaatgaatag agcaaataga ataatttacg accaaacagg
    26401 caaaatgctt ctccaaacag gagaagcaac aggggatgta ttggagtatg atacaataac
    26461 agaattgcat tgcattgata ttccgtatgg aagtatagat tatactaaaa atagaattat
    26521 aggtataaat atagaaacaa aagaaccaat tttagaagaa ataccagtat ttatctcgga
    26581 ggaagaaaaa agaatacaag agttagaaaa tcaaatttta ttaaatgaaa atgaaaaggt
    26641 aggaggaatt ttataatgaa tataaataat gttgtagtaa gaatattagc agagagaata
    26701 ttaaacggag gcttaaaccc tttaaaaaat cgagaatttg aactggatga tgtaactaat
    26761 gcagaataca gaaaagcagt agaggattat attatagagc atagtggagt agtagaagga
    26821 acacaaccta caaaataggt tcttttttta taggcttaga taattctaag tcttatttta
    26881 atgcaaaata aggaggaaat atgaacgtaa caatagtttt tttagcaaca aatatattta
    26941 taaaattagt aatattagca atagcatttg atacattgct aggttgttta agagcaataa
    27001 aaacacatca gtttaattca agttttggaa taaatggagg aataagaaaa gttgcaatga
    27061 tagcatgtat attttttcta gcagtagttg acattcttac aaagtttaac tttttattta
    27121 tgttaccaca agattgggtt gattttttgc gattaaatca tcttggaata tctgaatttt
    27181 tctctatttt atttattcta tatgaaagtg taagtatatt aaaaaacatg tatttgtgtg
    27241 ggttaccagt acctagaaaa ttaaaagata gaataggtag tttattagat actatgacag
    27301 atgaattaaa tgttaaagga ggtagtaaat aatgaaaata tgtataacag taggacacag
    27361 cattttaaaa agcggggcat gtacttctgc taatggagta gttaacgagt atcaatacaa
    27421 taaatctctt gcaccagtat tagcagatac ttttagaaaa gaaggtcata aggcagatgt
    27481 aataatatgc cctgaaaagc agtttaaaac taaagcagaa gaaaagattt ataaaatacc
    27541 tagagttaat agtggaggat atgacttact tatagagttg catttaaatt caagtggtgt
    27601 aggagccttt ggaacagaag tattttacta tagtgaaaaa gggaaggaat atgcgcaaag
    27661 ggtagtagat aaattatcta aacctttcat aagaaaaaaa ggagataaag aagtaggtaa
    27721 tagaggtgtt aaattagata aaagtttata tattttaaat agttctaaac ctactgcaat
    27781 actaattgaa agtttctttt gcgataacaa agaagattat gagaaagcta agaaactagg
    27841 tcatgaaggt attgctaagt tgattgtaga aggtgtatta aataaaaata taaataatga
    27901 gggagttaaa cagatgtaca aacatacaat catttatgat ggagaagttg acaaaatccc
    27961 tgcaactgta gttggttggg gctataatga tggaaaaata ctgatatgtg atataaaaga
    28021 ttatgtacca ggtcagacac aaaatcttta tgttgttggg ggtggagcat gtgaaaagat
    28081 aggttctatt actaaagaaa aatacacaat gataaaagga aatgatagat ttgatacact
    28141 ttataaagca ttagatttta ttgatagata gattaagaag gtagcaacta atttgctagt
    28201 tgctaccctc tttttttatg cctacttttc tttctttttc caaacaactt cgtaccctat
    28261 tagattagca atagtcaaga tttcgctata tttcatagtc tcattattta ttttttgcct
    28321 caaattttca actgtattat tcttattatt atgttcattc attaaattat ttaactcatt
    28381 catgctgata ttttctttca caagaatact tttgatttca tttttccatg tcattttttc
    28441 acacctctct tatttatata ataacataaa aaaattaaaa gtaaaagaat aatctatgtt
    28501 aatcaaagtt atattttcgg taatcaaaga aaaaactttg aaaaagtgtt gacttagata
    28561 ttcatataga ttataatata attaacaaat aaaacaaggg ggtaagcaaa gaatgaaaac
    28621 tttatttaaa gaagcgcata aaatagcaag agaaattaaa gaaaaatata atgatgtaga
    28681 ttataaagta caatttagtc tttgcttatc cttcttaaat aaaaaggggg atataaaaat
    28741 gaaagaatta aaagggtcag aaaaacaaat tatttgggct aatgatataa gagcagacat
    28801 tttaaattta actaacgaac tagaaaaaag taaactagaa agaataaaaa atgaagacta
    28861 caaaatcaaa gacatgagta tagaagaaat gatagaaaga tgtaaaagaa aatttgaaag
    28921 aataagagag gcaataagca acatagagga tgctaagttc tttatagata attttagaaa
    28981 tgttttaaaa tataattctt taaatcaaaa agcgtttcaa ataaaccaaa tttttcgaga
    29041 gtctcaattt acagaagaaa ttggaaattt aaaattttta aaaggagaaa ctcaagcgtc
    29101 tcataaactt agaaaagttg aaggtagtat aagctatgaa gaagctaaaa aaatagccaa
    29161 agaaataaat ttcaatgata attggtctaa tgaaataaaa gaaaatgtac ttgaaatagt
    29221 tgaaatattt gacgacgcag taaaacaagc tactagcaca gaatatatag agaaagctaa
    29281 aaaatacata atagaaacat taatacaaaa aaatgcacaa ttttatagaa atggatttgc
    29341 agacattaaa aagaagcaga ttgaaaacta tagaaaaata gaaagtgctg aaagaaaaat
    29401 agaaattgca taccaaatat ttagagatgg tgtagagtgt taaaaatttt ggattggtac
    29461 aaatatagtt caccgtcgaa tgctataatt ttaatatata aaataaatgg aggattgaag
    29521 tatgaatata gattttagta caatattaaa tttaaaagtt aataaagaga atgttgaaat
    29581 gatagaaaaa gagattaata aaatcaacaa tgatatattt gatataagtc ttaaagattg
    29641 tgcaaacggt cacgtgggaa tcgttaaaga aacagttgga aaaagtttaa acattgaaac
    29701 gtgggggcat ggtgaaatta acagtagcat aggaataaga ttgagattta atttttatta
    29761 ttcaaaaggc gacaaagtag acatagaaaa tatagaaaac attttaatat atgtaaatag
    29821 cttatgcagc aaaaatgtag aaagtgacct tatagctagt gtaagacctg gattttataa
    29881 attagaagag aaatattcta cacgcattga aaaatgcgaa attagacacg aatttacagg
    29941 cataaacaaa caagaaatta aagaattttt agagtatctt acagaaattg aaaagagcga
    30001 aagaactgtt atatataaaa aataactaaa aaatggagga tataaaaaat gaataaacaa
    30061 aaagctagaa gatttttaag agttatagat atgaacatgg ataaaataga agaagaagct
    30121 ataaaagctt ttaaagaaag ttgtttaatc aaagagacta ataatataaa aatttatatc
    30181 gatatacaag gaaaagttga agcgatagca gttcaaactt gggctaaact tttagacgac
    30241 gacaaagaaa ttaatatttt cacattaaat caaacaccaa ctcatttaaa cgatttgttt
    30301 ggagaaattt gttacgtaaa cgattatgaa gaatttgaaa attggtgtga aaacgagcgg
    30361 gaaattttgg attgggatag ttataaaaaa ttcaataaag aaaatttcga agaaattgct
    30421 gaaagaaata tagacgatag cacatcagtt tttttagaag aattacaaaa aagcattgaa
    30481 agttgtaaac aagaattaca aaatatagtt gaaaattaag tagaagagta ttattattaa
    30541 tgtatatagt atcgctttta agattaacta cgagggattt aaaatatttt ttaatttatt
    30601 tagaaataat attgtaataa gaatttttat attaactaca agggatttaa atgtcaattt
    30661 aatttataga gaaataatat aataacaatt tttaagatta actataaggg atttaaatat
    30721 caatttaatc tatatccata tgatacaata tccaatttta gattaactat gcggaaataa
    30781 aaacagtgta ttcaataaat acactgtttt tttaaaaatg tttagttatt atgataactt
    30841 aatccttcga ttataaatcc tacgttcatt gtcatttctg cttcgtcgct ttgcaatatt
    30901 ccttccgtaa attcgctatc gcttgataat gttatttttt tccttgccac catttccaaa
    30961 attgtttgaa atagtttaat tttcatattc ttatcaagtc cagcgtattg cagatagttt
    31021 gccacctcct gcgaaaactt atttaattca gatttagtca ttttttcaga taactctttt
    31081 ccaatttgca aataaacatt catcttttcc aacccctttt agattatagt taaaacatat
    31141 tatttaaaca atatcgatat attgtaataa taatattaaa atattactta aatattatat
    31201 atacaatatt taagtaatat ctaaacaata taaatataat attatttact ttttcttagt
    31261 cttatttctt ctatttctct cattgtatat atttaaattc tcttctttta tagtgacatc
    31321 agataaaatt tgagttagta catcacttaa taatttgctg acgtcgctgt tcatatcaat
    31381 agaaaaagat tttaatttgt ttacaagttc ttcatcaagc gttgcactca tagttacctt
    31441 tttacttttc ttattaacta gattatatat gtttaatgtc ttattgtctg tagttgtaga
    31501 attattttgt atgattgttc catttttttt gaaaactggt ttttctttat tagataaaag
    31561 ttcttcgtcg aattttggca tctacaacac tcctttcact tttagttctt ctaacatatt
    31621 agcaaactct tgtctgctga aatgctcttt agttattttt gtataatctg ttagagatag
    31681 ttttttcaat agtgccttct ctataaactc gttttttcta atatatgtat ctaacataat
    31741 atctctcata tcgttaaacc cttccagata agaatcgaaa gtatcactaa tttgagtttt
    31801 cttcttctca aatccaacca aaacagtact ttttatatta tcctccttat caaaataggt
    31861 tctatcaaca tcccagagtt gtttaaataa ttctgctcct cttaaagaag aaatgttttt
    31921 atcttgaatt ggaataatta tactatctgc taagaaaagc acatttttag ctgtcaaatc
    31981 gtagcgtgga gataaatcac agataatata atcatactca ctcaaagtat taaagttttg
    32041 catgtaccag cgagctaaaa atttttctct ggctggtaaa ggtgatagct cttgttcaaa
    32101 tctagccatt tgtatgtcag aaggaattaa gtctacatta atgtactttt cattaggtga
    32161 cttgactatt gcatcattag cactaatccc ttttaaaata tctaatgtag tattatcatt
    32221 atgatttatt tcataaacat attgtgttag atttgcttgt acatctaagt cccataagag
    32281 tattttttta tctttatctt tcgcaagttc atacgctgtc attatagacg ttgttgtctt
    32341 atagatacct ccttttatgt taaagtacgt aagtagcttt gtattagcca ttttctccac
    32401 ctcattatta tatttataat attataacaa tattgtagta ttgtttttat aatattgcaa
    32461 caatatatta atattgttaa ttacaatatt caaataatat aaatacaata tttacatatt
    32521 gcttttacaa tgccaatata ttatattaaa aatactaaaa tattgtatat acaatactaa
    32581 aataatattt ttataatatt acagtattat ttttatatta tagtaaaatt taaaaaaaag
    32641 aaggctaaga aaaaaagcaa ccttctttta tagaaaaagt cattcattct tagccttttc
    32701 aattattatc ctgtcgccct cgaatgttgc cgtaacatta gggttttctc ttgttatgcc
    32761 catttcatca gcccattttt taggaacact cattctagga gtaaacgacc cactcccacc
    32821 tttgtgaaag ttaaacttta aatctctttt ttctttttcc attcattagc tccttttttg
    32881 ctgtattaca aagaaaagca ataatacaac actaaaaact aaaccgagca tgttgcttgt
    32941 actagagttt aatactatag atactatatt taagactata gttatcaaaa ctaaaacaat
    33001 gcaaatctta taaaatttat cactcatgtt ttttttagaa atgtgttata atattagaaa
    33061 gaagtcacct agagagaagg gctattccct ctaggcttat ccttacagtt ctttcaaaat
    33121 tcttagaact gcgaggatta tgttaagtaa taataggatg aaggagaaaa cttttttaac
    33181 tatgttaaat ttgttttctc ttttcttttt acttctttct aatctcccca ttcccgttcc
    33241 tcctttcttt tatttttttg ctttctcacc tccttctcta taaatatatt ataccatgac
    33301 gggtcgtcaa aaacaatagt tttctcctat tttttaaaca aattttggta aaaagtaaag
    33361 attttagtat attagaaatg atgtaaaatt gtatcttttt ttaaaaaatg tgatataata
    33421 aaagcaagga aataatgatt tactttacac aagagtagct atttccaatg ttttgaaaaa
    33481 taacttattt tcttaaacca ctcttattgg cgtttgagtg gttttttaat tttatcgttc
    33541 ttaaaataaa ctttgataaa aataaaaaaa atagaatact gaaaatgatg taaagttgta
    33601 tcttttaaag aaaatgtgat ataataaaag caagagaact gtattctagt cataagagta
    33661 gagttttagt ctaaaataaa aaattattta aactttttga atttgattct caaatcaaat
    33721 tcccaaccac tcttttgcgc agagtggttt tttacttgtc taaataattt gctaattata
    33781 tagaatatta aactagctat aacaccagct aatacattaa gtaaaaaatt atccatactt
    33841 catcacctcc ctttgtagcg ttgggaggat aatcttttgt gtatagactc cactcttttt
    33901 ttagaatata gattgctttc tcttgctaaa attattataa catatattta cataaaaaaa
    33961 gacttagttt atatactaag tcttttaaaa tgcagtattt tagaaaatat atttttaaaa
    34021 tataatttat tttcaaaaag agtatatttt tttataattt aaatgtgcta taattataat
    34081 cacaacgaac agaaaacttt tttttaattg gtttaaaaaa atctacaaaa aaataaacaa
    34141 ggaacatgta cttgccgtca aacaaaccat gttccttaca ccggaggtta gacctctctt
    34201 aaggataata tatccttgtt tttctatact tatatttata ttataagaca aagtgtagaa
    34261 aaacacaatg gttttaaggt aattttaata gtaaaattat tacaaaaaat caaaaaaaga
    34321 gcgtcagcct ccaggtggaa attggaggga taaagatgaa gaatgttaat aaaaataata
    34381 tagataagat gtttttagaa gaatgtagcg ctgaaagagc agagcatgaa aaagaaaatt
    34441 attcaaattt caatagacat gaaacatatg aaataaaaaa atatataaac gaaaaaaaac
    34501 taggaattaa aacggctata gccaacgcga taaatggcgg gaaaaccctg tttattgcac
    34561 cgacaggagc aggaaaaagt tatagcttta taaatacatt aaaaaaatta aaaacaaaag
    34621 cgttattcat acttccaaat gcttcaaatg tggagcaggc aatgcacgag tatgatatac
    34681 caggagcata tgacaaaata cctgttagcg aagcatttaa aaatggtaac ttagttgtaa
    34741 tgacttggga taaaactgaa aaacttataa acacagactt aagtgaatac ataattgtag
    34801 ttgatgaaat acatcaaact tatacagatg catatcgagg aaaagcaata aaaaatctaa
    34861 ataatataat gtctaagtgc aaaggaagaa tagacattac agcaacacca acaaaacttg
    34921 aatttgaaat atatgactac ataatagagt acactcaaaa gcaaaaaaca gaatataaag
    34981 ttaaattgta caacgacttt gacaataaaa attttactga aatgattaac ataataaata
    35041 aatctaaaaa cagcgccatg ttgatgaatg atatatcaac attagaattt ataagagatt
    35101 cagtgaacaa aaaagttgga gttgtatatg cagatggaaa agaagagaat gaattgtaca
    35161 atagaatagt taaaaattca gacatgaaag actatgaaac gcttttaaat acaacaacaa
    35221 tcctagctgg tgtaaatata aacaacaaag atatcacaga tataattatt gttaatataa
    35281 aagatgttgg agctataaaa cagtatgttg caaggtttag aaacttaaaa aaagtaaatg
    35341 tacacatatt caataaatat gaagaagagt gcaatgtata caaaattgaa tggctagtta
    35401 acaaaaatat agaaaaagca actatcttaa aagatgctta taacaaagta tctaaacaca
    35461 tgttacagtt tgaaacagtt ggaataaatg caacgccaat tcgcatagac tcaaatgtgt
    35521 actactgtac aaaagataat tgctataaag tagataaatt atatataaaa agtcaagttt
    35581 acagcaacta ttacaataca agaacaattc aaagttttaa agtgttatta gaagaatatt
    35641 ttgaaaatgt taatataact gatgctaaag aagttggcac aaatgaaaaa gagttaaaag
    35701 agtacaagaa agttgtaaaa gaaattaaag atgcaacaag agaaatttta aaagaacata
    35761 aagaaattct agtaggttat agacagatta aaagcgattc taagagcttt tcactaatgc
    35821 agtatcataa tgatatgaaa ctaagttcaa aagggtgctt agaggcttac agagcgtatg
    35881 acatacataa tttggtaaag aaaagtaaaa gtaatagcat gttagaacta tattctaatt
    35941 atgtactaga taataagttc gacttagacc ttgcttggaa actagcgaat acagcaaaca
    36001 aaagacgtgg ggtaatattt aataaaataa atactttaat atatagagaa ttaaaagagg
    36061 aatatccaga gtttttaaat gatgaactta ttcaagttac agtatttaat tatatagata
    36121 aattgtttgg aattggaaca tcttataaag aattgcattt acaagagtta agtaacgact
    36181 taagaacaat tttaggggaa aactgggatt taacaactaa aaagctaagc gttacactga
    36241 atggaatttt tattatagaa aagaaaaaat atagtaactg gcatgatata gaaactatgt
    36301 ttttttataa aaatataaat cctatatcat gccagtttga aaaaaaacga atacaactta
    36361 ataatataaa aagatatata actgtagatg acataaaaaa agatttagaa ttagacgaaa
    36421 aagataagag tttagaaaat gctataaaat atacaaaaga caggatgttg aactctttag
    36481 atgaagatga aaaactattg ttattaaaag gttttatgta agaatttgga cttaacaact
    36541 aaaaaaatag agattatatt gaatgaaatt tttataatag
//
LOCUS       DAMJWC010000039        36209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMJWC010000039 DAMJWC010000000
VERSION     DAMJWC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.039"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            31..1143
                     /locus_tag="PC503_002216"
     CDS             31..1143
                     /locus_tag="PC503_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF2528188.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENI
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1397..3421
                     /locus_tag="PC503_002217"
     CDS             1397..3421
                     /locus_tag="PC503_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2528189.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3641..4327
                     /locus_tag="PC503_002218"
     CDS             3641..4327
                     /locus_tag="PC503_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF2528190.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4422..5477
                     /locus_tag="PC503_002219"
     CDS             4422..5477
                     /locus_tag="PC503_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF2528191.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5592..7148
                     /gene="murJ"
                     /locus_tag="PC503_002220"
     CDS             5592..7148
                     /gene="murJ"
                     /locus_tag="PC503_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2528192.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7194..8900
                     /locus_tag="PC503_002221"
     CDS             7194..8900
                     /locus_tag="PC503_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2528193.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="PC503_002222"
     CDS             8922..9995
                     /locus_tag="PC503_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF2528194.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="PC503_002223"
     CDS             10007..10729
                     /locus_tag="PC503_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2528195.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="PC503_002224"
     CDS             10745..11902
                     /locus_tag="PC503_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF2528196.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLSIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="PC503_002225"
     CDS             11905..12744
                     /locus_tag="PC503_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2528197.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="PC503_002226"
     CDS             12759..13934
                     /locus_tag="PC503_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF2528198.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="PC503_002227"
     CDS             13963..14712
                     /locus_tag="PC503_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2528199.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="PC503_002228"
     CDS             14734..15642
                     /locus_tag="PC503_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2528200.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="PC503_002229"
     CDS             15690..16442
                     /locus_tag="PC503_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2528201.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16396..17763
                     /locus_tag="PC503_002230"
     CDS             16396..17763
                     /locus_tag="PC503_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF2528202.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17769..18860
                     /locus_tag="PC503_002231"
     CDS             17769..18860
                     /locus_tag="PC503_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2528203.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="PC503_002232"
     CDS             18944..20857
                     /locus_tag="PC503_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2528204.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21056..21763
                     /locus_tag="PC503_002233"
     CDS             21056..21763
                     /locus_tag="PC503_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2528205.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="PC503_002234"
     CDS             22065..24176
                     /locus_tag="PC503_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF2528206.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="PC503_002235"
     CDS             complement(24374..25339)
                     /locus_tag="PC503_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2528207.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="PC503_002236"
     CDS             complement(25624..26580)
                     /locus_tag="PC503_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2528208.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="PC503_002237"
     CDS             26948..27736
                     /locus_tag="PC503_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2528209.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="PC503_002238"
     CDS             complement(27859..28329)
                     /locus_tag="PC503_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF2528210.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="PC503_002239"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="PC503_002239"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF2528211.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29155..30060
                     /locus_tag="PC503_002240"
     CDS             29155..30060
                     /locus_tag="PC503_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2528212.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="PC503_002241"
     CDS             30375..31922
                     /locus_tag="PC503_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2528213.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="PC503_002242"
     CDS             31925..32323
                     /locus_tag="PC503_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2528214.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="PC503_002243"
     CDS             32363..34096
                     /locus_tag="PC503_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2528215.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="PC503_002244"
     CDS             34328..35539
                     /locus_tag="PC503_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2528216.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35732..35992
                     /locus_tag="PC503_002245"
     CDS             35732..35992
                     /locus_tag="PC503_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF2528217.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
BASE COUNT        14505 a         3789 c         6364 g        11551 t
ORIGIN      
        1 atttcaaata atgctgtaga ttctaaactt atgaatagta ggattaaatc aatagatata
       61 ataagagggc tatcaatagc cctcatgata gtctgcaata atcctgggac ttggatgaga
      121 atgtatcctc aattaagaca tgctgtatgg catggtgtaa cacttgcaga ttttgcattt
      181 cctttttttg ttatatcttt aggtgttaca attccaatat caataaatag taaactaaaa
      241 aataataaat ccacactgag tataatactt agtatattca agagaagtat cttattgata
      301 ttatttggat ttttcttaaa ttacctagga aatcctgatt tagatactgt aagaatactt
      361 ggagtacttc aacgtatggg attagtctat tttgtgacta gtttagtata tttactacta
      421 aaaaaattaa atgttggaag tactgctaca ataattactt ttctatgtat atctacattt
      481 ataatagttg ggtactacat attagcaaaa ccttatggat ttgagctaga aggttctctt
      541 gcacagttag tggatttaca tttcttcaag ggacatttgt acaagccgga atttgaacca
      601 gatggttttt taactagtat agtagcaatt tcttcaggta tgttgggatg cactatggga
      661 tgtgtacttt taaaagaaaa cataggagaa tataaaaaat tctttaaaat actggttatg
      721 agcataatcc tgctaatagg tgcttttatc tttaatcagt attttccatt taataaaaga
      781 ttatggtcta gctcatttgt acttttaatg gctggcagtt atggtatatt actgtcaata
      841 ttttatttta tatgcgacat caaaaataaa agtaaaatat ttaccccaat aatagcactt
      901 ggaagtagcc ctatttttac atatatgtgc cttgaaatat tgagtcatgt tttttggaat
      961 gttccaaaac ttacgaacaa agtcgattat ccaactacct tggtagagtg gactacatat
     1021 gaacttataa caccttgggc aggtacaact tgggattctc ttatattttc tttattgtat
     1081 gtcctattct gggttatagt aatgtctata atgtacaaga aaaaaatatt tattaaaatt
     1141 tagtgcaata tttttagatg ataaagtctt tgatttgttc aaatatacgg aaactatcaa
     1201 atataatcaa aatttctcct cgataaaatt taaaaaccat gccataaaag attacaaaaa
     1261 gtttacaatt tgtaattttt tgtgctataa tgaaaaaaga tttacataat attgaattta
     1321 tgtaatataa aacaagctta agatgtatta aaaaagattt aaagatttaa agaaccaaaa
     1381 aattaggggg gatatgatga aaaaaacaac aaaattattg gcaacaggaa tgttgtctgt
     1441 agcaatggtg gcaccaaatg tagctttagc ggctgaaaat actactgcaa atacagaatc
     1501 taattcagat attaatataa atttacaaag aaaaagtgta gtgttaggaa gtaaatctaa
     1561 tgcaagtgta aaatttaaag aaaaattaaa tgctgattca ataacattaa attttatgtg
     1621 ttatgatatg ccacttgaag ctactttaaa ttacaatgaa aagacagatt catatgaagg
     1681 tgtaataaac tataacaaag acccagaata cttaaatgta tgggaacttc aaagcataaa
     1741 aataaatggt aaagatgaac agaaagtttt aaacaaagaa gacttagagt ctatgggatt
     1801 aaatcttaag gattatgatg ttacacaaga gtttataata agtgatgcaa attcaacaaa
     1861 agcagtaaat gaatatatga gaaaaacttc tgcaccagta aaaaaacttg ctggagctac
     1921 tagatttgaa actgctgttg agataagcaa acaaggttgg aaagatgggt ctagtaaggt
     1981 tgtaatagtt aatggagaat tagcagcaga tggaattaca gctactccac ttgcatctac
     2041 atatgacgca ccaatattac ttgcaaataa agatgatata ccagaaagta caaaagcaga
     2101 gttaaaacgt ctaaatccaa gtgatgtaat aattataggt gatgatggtt cagtttcaca
     2161 aaaggcagtg tctcaaatta aatctgctgt aaatgtaaat gtgactcgta ttggtggagt
     2221 tgatagacat gaaacatctt tacttatagc aaaagaaata gataagtatc atgatgttaa
     2281 taaaatatac atagcaaatg gatatgctgg tgaatatgat gctcttaata tttcatcaaa
     2341 agctggtgaa gaccaacaac ctataatatt agctaataaa gattctgtac cacaaggtac
     2401 atataattgg ttatcctcac aaggtttaga agaagcttat tacataggtg gtagtcaaag
     2461 tttatcatca aaaattatag accaaatatc taaaatagca aaaaatggta cttcaaaaaa
     2521 tagagtttct ggagcagata gacatgaaac aaatgcaaat gtaattaaga ctttctatcc
     2581 agataaagag ttgagtgcaa tgttagttgc aaaatctgac ataatagttg attcaataac
     2641 agcaggacct ttagcagcta aattaaaagc tccaatactt ataactccaa aaacttatgt
     2701 ttctgcatac catagtacaa acttatcaga aaaaacagca gaaacagtat atcaaattgg
     2761 tgatggaatg aaagatagtg ttataaattc tatagcatct agtttatcaa aacacaatgc
     2821 accaacagaa ccagataatt caggttcagc agcaggaaaa actgtagtga tagacccagg
     2881 tcatgggggt tctgattcag gggcaacaag tggattaaat ggtggagcac aagaaaagaa
     2941 atatactctt aatacagcat tagcaactac tgaatattta cgttcaaaag gtataaatgt
     3001 tgttatgact agagatacag ataaaacaat ggctttagga gaaagaacag cattatcaaa
     3061 tactataaag ccagatttat ttacaagtat acattacaat gcgtctaatg gatctggtaa
     3121 tggtgtggaa atttattaca aagtaaaaga taaaaatggt ggaacaacta agactgcagc
     3181 atcaaatatc ttaaaaagaa tactagaaaa atttaatatg aaaaatagag gaatcaagac
     3241 aagaacactt gataatggaa aagattacct atatgtgtta agaaataata attatccagc
     3301 aatacttgtt gaatgtgcat ttattgacaa taagagcgat atggataagt taaatactgc
     3361 agaaaaagta aaaacaatgg gaactcaaat tggaatagga atagaagata cagtaaaata
     3421 aaatagaaaa tattaaagca aaacatatca tctcctgtta taatgtaaaa tataacaaga
     3481 gatgatatat ttttgtaaag aatcaaattg tttacaatga tgtttcttgt attgataatc
     3541 tgctcattat tgagtataat atagaaataa gtcaaaaata agatagaaat aagttgaaat
     3601 taagaattaa aaaaattttt attccaatat ggaggtaact atgtctggat atactaatga
     3661 tgagtgtgaa atacctaaaa ttaaaagcta tccaggggca gataaagaaa ttgcaagtga
     3721 gattgactat agcatagtaa aaggaacagt tttattcgac ttgtaccaaa gaattatgga
     3781 tttagtttta tctataatag gacttgtgat aggtttacct ttaatagcaa tatttggaat
     3841 tcttattaaa atagaggaca aaggaccaat aacttataag caagaaagac taggaaaatg
     3901 cgggagaaga ttctatatat ataaattgag atctatgaga acagacgcag aaaaatttgg
     3961 cgcacaatgg gctgaaaaag atgatcctag aataactaag gttggaaagt ttattaggaa
     4021 aactagaatt gatgagattc cacagctgtt taatatatta aagggggaca tgggcttaat
     4081 aggtcctaga ccagagagac cgaactttac tgttcaattt aatgaggaaa tacctggatt
     4141 tatcaacagg ctcgctataa aacctgggct tacaggttgg gcacaagtaa atggtggata
     4201 cgaaatcact cctgaagaaa aacttaaaga agatatttac tatataaaaa ataggagtat
     4261 attacttgac tttaagatac tctttaaaac tgttaaagta gtattgacag gagacggagc
     4321 tagataattt taaaatatta gattactaat caatgaaaaa gctctttaaa aagagctttt
     4381 ttattgtcaa aaaatacaaa aaagaaaagg aatgagaact tatgattaaa aaaatttcta
     4441 ctatattatc gttagttttg ttaatctcta tttctagtac gataggagta tttgcagatg
     4501 caaatcccaa aagagaattg atagaaggga gtataccaga gatttcgaca gaattaaata
     4561 aaagagcatt taaggattct aaagaagtaa ttcttgtaaa tgaagagtca attgtagata
     4621 gtataagtgc aacaccttta gcatatgcaa aaaatgctcc aatagttgta actaagagta
     4681 aaaatcttgg tagagtaaca agaaattatc taaaagaact aggtccagag aaggttacga
     4741 tagtaggtgg tttaaaggca gtatctaaag atgctgaacg taatatagaa aaaatgggaa
     4801 tgaaagtaga aagaataaga gggaaagaca gatatgatac atctttaaag atagctagag
     4861 aaatgtatag aacagtagga tttgatgaag catttttact tagctcaaca acaggattag
     4921 agaacgccat atctgtatat tcttatgccg ctaaaagtgg aatgccaata atatgggcta
     4981 aagatgaagg gtttgaggaa caaattgatt tcttaaaagg caaaaatctt aaaaaaatat
     5041 atgcattagg tgattcaaaa gagtttattg cagagattga ttctaactta aaaaatatag
     5101 aaggaataaa gcaaataaat aagtcaagta caaatgttga tttaataaag aagttttatg
     5161 atgaaaaaga tataaagaaa atctatactg ctagattaga ctttggtagt agatctgatg
     5221 taaacgaata tatttctttg ggagtagtat cagcaaaaga aaatatgcca atactgattt
     5281 gtagtgataa cttaagtcgt gcacaagata aattcttgaa agatagcaat ataaatgatg
     5341 tagttgaagt tgggtataca gtaggtgatt atagtctatt taagagcata tttaatctaa
     5401 cattcttatc ttgtatagta ttaatactat tattactatt gattacattt agggcactta
     5461 gatatgagtc gaaatagttt ttgatttata aggaagcttt tcataggtta aatttactta
     5521 attagaataa tgtttataag cagttttaaa agttctactt ttagagttta aattagataa
     5581 ggagaaagaa gatgtcaaaa acagctaaag cagcattgtg gattatggca gccactatgt
     5641 tttcaaaagt attaggtttc cttagagaac ttgtacttgc aaatttctat gggacaggta
     5701 tgtatgcaga cgtatttgta ttaacattaa atatacctgg tttaatcata gcagtcatag
     5761 gctctgcagt tgctacaact tatataccta tgtactttga gacaaagaaa agactcggag
     5821 atgaaggtgc cttaaaattt actaataatg ttttaaatat atgctatata atggctatag
     5881 taatagctat tattggtctt ttatttacag agcaatttgt tacagtattt gcagcaggat
     5941 ttagaaacga ccctgctaag ttccaagcag caatattatt tactaaaata atgatttcag
     6001 gagttttatt cctgagtgga agtaagatat ttagttcgtt tttacaggtg aatgacagtt
     6061 ttgtaattcc tgggcttata ggaatcccat ataatattat aataatagca gcaatagcac
     6121 taagtgcagg taaaaatgta tggatactgc cagcaggagc actattggct atggcaagtc
     6181 agctattgtt tcaactgcca tttgcgttta agaagtccta caagtataag ccatatataa
     6241 atttaaagga tgagtccata aaagagttag tcaacctagt attgcctatg ttggtaggag
     6301 tagctgttgg acagttaaat atatttgttg accgattatt ggcaaccact ttgggtgatg
     6361 gaaagttgtc tgctcttaac tatgcaaata ggctaaatga gtttgttatg gcattatttg
     6421 ttacatctat aataacagtt atatatccta aactagcaaa aatgtctggt aaagataata
     6481 aagaaggatt tataagtact attgtaaaat cttcaaattg tattatattg gtggtgcttc
     6541 ctatatctat aggagctatt atattagcag agcctcttgt tagaatatta ttccaaaggg
     6601 gtaaatttga tgcgttatca acagacctta catctatagc gcttagatta tattcactag
     6661 gtttattggc ttgtggagta agagatgtct tatatagggc attttactct ctttcagata
     6721 caaaaacgcc aatgataaat ggaagtatag ctttaataat aaatatagtt cttaatttaa
     6781 tattgataag accattgggt catgcaggta ttgctatatc aactagtaca tcaaacataa
     6841 ttacagttat attattattt atatctctta aaaagaaaaa tggatatttt ggaggggata
     6901 aaattataaa gactggtcta aaaagtttgg tagcatctgg tgtgatggca gtagctactt
     6961 tattgatata taataatcta tatgcattta tgggttcagg aacaattaaa gaaattatat
     7021 cagttggagc tggagtatta ggtggagctt ctgtatatac tgtattgata gttttattta
     7081 aggtagaaga gatggattta gcttttgaat ttttaagaaa aggaaaacaa aaactactta
     7141 gaagatagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgaacaa acgaaaaatg
     7261 agctattaag tataaaagat gatgaaaaag aaatacaaga tagattttat aaaaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaaaact caaggagaag
     7441 aaggtaagca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagtac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa gccagtaaga aaagtcttaa atgaatgtgg ctttgaaaat gtaatggtag
     7981 ttaaggagca agaattgcca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa caatggcact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggc atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggt tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat actatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tactagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa gatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa tatcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacaa
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagagc
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aagataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatatgga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgac aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcagcat gttttttaat
    11101 ggtagctata ttattattta atctatttcc ttcattgata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actaccaatg ctcctaaaga cattatcgat
    11461 aatacttact ttatttagtg taattattgg tacagtattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggacagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag acaatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaataaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagacta tacaagattt gatgagaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataacta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attataagtt tgcaaaagtt atggtatcaa aacttgtaag aaatatagga
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagt tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt ggaaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatttt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagta gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta tagaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gattatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagtaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcaacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaagaagat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggttcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat gatgtaaaag tagaacttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctac atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaggaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa taggatatgg tggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaggttgctg ttttaggttt gacttttaag ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgctcgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaacta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagcgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcctataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa tccagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaaaata aaattggaag aataatccac aatgtgaaaa ttgtaggaac
    19561 aacttcagat ataaaagatg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaattg cttagaaaat ataaaaataa
    19981 attagattta aaaacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatt attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtacttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat ataaatgggg agcaactgga ccaaattctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggagtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca cgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgctgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaat
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggatgattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatcgagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg tataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtattagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttga aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactactcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatga
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtcg cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatatata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagtaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 attaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagcatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgcaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggtcagta cttattatgc aaagtttaaa attgtagaag atttgacgaa
    27361 agtagaagga gacatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 tataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgcc ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatagat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaaatcctt tgcatcaaag atttttgatt cctttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggactaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatggttg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agacttgata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actaatcaac aacaaaatgt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttgcaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaattttaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaagaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttactcac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaacct tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatt aagaataaaa
    30901 ttgtgatact aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaagact taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcac
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caaccttaag gggataccac
    31621 tagatattat aaaaattgat aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt gttaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa gattatagat attttaaagc aaggagggat
    33001 tggcagtgtt ataactccaa gatatttttt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaatata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaggatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataataatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttagaga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatctttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atatagttca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaacta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaaccgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg atttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa aatggaaaaa gtagttagta tcaaaaatgc
    35761 aagtggatta catgctagac cagcaggaat gtttgttaag aaggcagctg aatttaaatc
    35821 aacagtagag gttgtagcaa aagacaaaac tgtaaatgca aaatcaataa tgggaataat
    35881 gagtttaggt ttagctcaag gagaagaatt aaagttagtt gtaaatggag aagatgaaga
    35941 agtagcttta gctgcaatgg ttgaattagt tgaaagtgga tttggagaat agatataata
    36001 attttttaaa aatttgatat ttagaatcta atattactta aagtaaagta acagagaagt
    36061 attaaacata tacagaccaa catttgtaga tatttaattt ctttgttact ttcatgttta
    36121 tttaatcaga agattaagac tattgttaat tgggtataaa aatataaata ttttagaaaa
    36181 tgaaataaga tatttttaat cataaattc
//
LOCUS       DAMJWC010000040        35891 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMJWC010000040 DAMJWC010000000
VERSION     DAMJWC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35891
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.040"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(359..871)
                     /locus_tag="PC503_002246"
     CDS             complement(359..871)
                     /locus_tag="PC503_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2528218.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            1321..1797
                     /gene="purE"
                     /locus_tag="PC503_002247"
     CDS             1321..1797
                     /gene="purE"
                     /locus_tag="PC503_002247"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF2528219.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDNNLRG"
     gene            1803..2501
                     /locus_tag="PC503_002248"
     CDS             1803..2501
                     /locus_tag="PC503_002248"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2528220.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            2513..3880
                     /gene="purF"
                     /locus_tag="PC503_002249"
     CDS             2513..3880
                     /gene="purF"
                     /locus_tag="PC503_002249"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF2528221.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            3874..4950
                     /locus_tag="PC503_002250"
     CDS             3874..4950
                     /locus_tag="PC503_002250"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF2528222.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMERYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAVAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            4944..5537
                     /locus_tag="PC503_002251"
     CDS             4944..5537
                     /locus_tag="PC503_002251"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF2528223.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            5530..7062
                     /gene="purH"
                     /locus_tag="PC503_002252"
     CDS             5530..7062
                     /gene="purH"
                     /locus_tag="PC503_002252"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF2528224.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            7073..8323
                     /gene="purD"
                     /locus_tag="PC503_002253"
     CDS             7073..8323
                     /gene="purD"
                     /locus_tag="PC503_002253"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF2528225.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            8348..12154
                     /locus_tag="PC503_002254"
     CDS             8348..12154
                     /locus_tag="PC503_002254"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF2528226.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKETSIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            12360..13232
                     /gene="rfbD"
                     /locus_tag="PC503_002255"
     CDS             12360..13232
                     /gene="rfbD"
                     /locus_tag="PC503_002255"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF2528227.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            13341..14210
                     /gene="rfbA"
                     /locus_tag="PC503_002256"
     CDS             13341..14210
                     /gene="rfbA"
                     /locus_tag="PC503_002256"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF2528228.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            14259..14816
                     /gene="rfbC"
                     /locus_tag="PC503_002257"
     CDS             14259..14816
                     /gene="rfbC"
                     /locus_tag="PC503_002257"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF2528229.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            14854..15837
                     /gene="rfbB"
                     /locus_tag="PC503_002258"
     CDS             14854..15837
                     /gene="rfbB"
                     /locus_tag="PC503_002258"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF2528230.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            15867..16535
                     /locus_tag="PC503_002259"
     CDS             15867..16535
                     /locus_tag="PC503_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2528231.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVNQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            16544..16972
                     /locus_tag="PC503_002260"
     CDS             16544..16972
                     /locus_tag="PC503_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF2528232.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            16996..17310
                     /locus_tag="PC503_002261"
     CDS             16996..17310
                     /locus_tag="PC503_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2528233.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVKVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            17461..17736
                     /gene="flgM"
                     /locus_tag="PC503_002262"
     CDS             17461..17736
                     /gene="flgM"
                     /locus_tag="PC503_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF2528234.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            17741..18157
                     /locus_tag="PC503_002263"
     CDS             17741..18157
                     /locus_tag="PC503_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF2528235.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGNDISMSEVVENSNDGYLKEIYTDLKRILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            18175..19485
                     /gene="flgK"
                     /locus_tag="PC503_002264"
     CDS             18175..19485
                     /gene="flgK"
                     /locus_tag="PC503_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF2528236.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            19504..20436
                     /gene="flgL"
                     /locus_tag="PC503_002265"
     CDS             19504..20436
                     /gene="flgL"
                     /locus_tag="PC503_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF2528237.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            20452..20844
                     /locus_tag="PC503_002266"
     CDS             20452..20844
                     /locus_tag="PC503_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF2528238.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            20838..21050
                     /gene="csrA"
                     /locus_tag="PC503_002267"
     CDS             20838..21050
                     /gene="csrA"
                     /locus_tag="PC503_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF2528239.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            21072..21467
                     /gene="fliS"
                     /locus_tag="PC503_002268"
     CDS             21072..21467
                     /gene="fliS"
                     /locus_tag="PC503_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2528240.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            21467..21823
                     /gene="fliS"
                     /locus_tag="PC503_002269"
     CDS             21467..21823
                     /gene="fliS"
                     /locus_tag="PC503_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2528241.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            21844..23367
                     /gene="fliD"
                     /locus_tag="PC503_002270"
     CDS             21844..23367
                     /gene="fliD"
                     /locus_tag="PC503_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF2528242.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            23370..23705
                     /gene="fliT"
                     /locus_tag="PC503_002271"
     CDS             23370..23705
                     /gene="fliT"
                     /locus_tag="PC503_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF2528243.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            23807..24679
                     /locus_tag="PC503_002272"
     CDS             23807..24679
                     /locus_tag="PC503_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF2528244.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            24772..26913
                     /locus_tag="PC503_002273"
     CDS             24772..26913
                     /locus_tag="PC503_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2528245.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            26937..28814
                     /locus_tag="PC503_002274"
     CDS             26937..28814
                     /locus_tag="PC503_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2528246.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            28807..30921
                     /locus_tag="PC503_002275"
     CDS             28807..30921
                     /locus_tag="PC503_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2528247.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDRIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            30930..31925
                     /locus_tag="PC503_002276"
     CDS             30930..31925
                     /locus_tag="PC503_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF2528248.1"
                     /translation="MNNIHINKFEKSCERNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            32017..33249
                     /locus_tag="PC503_002277"
     CDS             32017..33249
                     /locus_tag="PC503_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2528249.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            33269..34213
                     /locus_tag="PC503_002278"
     CDS             33269..34213
                     /locus_tag="PC503_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF2528250.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ELFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            34307..34714
                     /locus_tag="PC503_002279"
     CDS             34307..34714
                     /locus_tag="PC503_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HDF2528251.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            34801..>35891
                     /locus_tag="PC503_002280"
     CDS             34801..>35891
                     /locus_tag="PC503_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF2528252.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
BASE COUNT        14701 a         3613 c         6545 g        11032 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaata aaatacttta atgaaaaata gctaacttta attgtaggat attcttaata
      181 tatttgaaat aaataaaaat attgaaggat ataatattca actggtatat aaataataaa
      241 tgatagttaa attttacctt agaggctaat taggtgttta gtcaaagcta atgcctttag
      301 aatacaaatg tattctaaag gcatttttac tatgtatttt catttatatt actaaacatt
      361 atctattttt atatacattt ctatgtattt tattttcatc aaatcggtct ataaactcat
      421 ttttttcttc actatatcca atagatataa gtgcataagg aactaatttt aatggtaagt
      481 ctaaagtttg tctaacttta tttaccactt tatttttagg aaatactcct gcccaacaag
      541 cagctagacc ttgattagta acttctaata ataaattttg tgtgcaagca cctaaatctt
      601 gtatccattt accaggtttt aagaatttat ctctatttcc aagcactact atacataatg
      661 gtgcaaattc tatatgcttt gctctatgct gtgactttga gagctgtttc agcagttcct
      721 tatcatctac tataataaat tcccaaggtt gagcattttt tgatgaaggt gcttgcatag
      781 ctgattttag tatttcagtt attttatctt cttctatatt tttatctata tatgttctta
      841 ttgaacgtct attttttata acttctaaca tacagattct cctttaaata aaattatttc
      901 tatttatata atatcattac tttaaatttt agctattact tatataaaga ataaactttg
      961 tgttggtttt atctaagtaa aagtaacatt cagaactaaa aaacaagact ataaatccaa
     1021 agtattaatt aaaaaagaag taataaaaaa taatatacaa gatttaaaaa agagtattgg
     1081 gcttaaaatt taattagaaa accaattttg agataatctg ttttttattt taacaaaaaa
     1141 acataaataa agttcgatac gtagcgaatg aaaaaattac aagaaatatt ttttttaaaa
     1201 aatttcaaaa aagagttgat aatatatgta tattaatata aaatttaagg tgtataattc
     1261 gtataataat acgaatgatt tgtagtgtaa aataacttat aaacggagag gggaagtcta
     1321 atgaaagtag cagtagttat gggttcaaaa tcagattatc caaaattaga agaagggata
     1381 aaactgcttg aaaaatatgg aatagaagtt gtagcaagag cattatcagc tcatagaaca
     1441 ccagaacaac tttcaatatt cctaaaagaa atagaagatg atactgatgt aataatagca
     1501 gcagcaggaa aagcagcaca cttaccaggt gtaatagctt cacaaacatt aattcctgta
     1561 ataggattac ctattaaatc atcaactatg gatggactag actcactttt atcaatagtt
     1621 caaatgccaa aaggaatccc agttgcaaca gttacaatag acttaggttt aaacgcagct
     1681 ttattggcat tacaaataat gactttaaaa tacccaaaat taaaagagga tttgaaatca
     1741 tatagagaag agatggcaca aaaggtgtta gaagacgaca ataatttaag ggggtagcag
     1801 aaatgttatt atatgaagga aaagcaaaac aagtatattc tacagataat gaaaatgaat
     1861 atgttgttta ttataaagat gatgcaacag catttaatgg agaaaaaaaa gcagaaatat
     1921 cttcaaaagg tatactaaat aataagatat caacaataat ctttgaaatg ttaaaagaaa
     1981 ataatataaa tactcacttt ataaaaagtt tatcagatag agaaatgtta gttaaaaaag
     2041 tagagatttt accattagaa gtaatagtaa gaaatattgc tgctggttct atctgtaaaa
     2101 gagttggtct tgaagaaggt gtagttttcg atgagccaat ttttgaaata agctacaaaa
     2161 atgatgctta tggtgaccca atgctaaatg atgattatgc agtggcaatg aagttagcaa
     2221 ctagagaaga gttaaaattc ttaagagaag aaactttaaa aataaatgag ttactaaaag
     2281 catttttctt aaaattaaac ctaaagttag ttgactttaa aatagaattt ggtaaggatt
     2341 ctgaaggaaa tataatattg gcagatgaag tatcaccaga cacttgtaga ctttgggatg
     2401 taaatacaaa tgaaaagtta gataaggaca gatttagaaa agaccttgga gaccttgtag
     2461 aaggttatac ggaagtactt tcaagaatga ataataaata ggaggcaaat gtatgtgtgg
     2521 agttttaggg atttactcta ataaagatgt aactaaagaa ctatattatt ctttatattc
     2581 tatgcaacac agggggcaag aaagctgtgg tttagctctt ttagatgatg gagaaattaa
     2641 gtacaaaaaa gatatgggat tagttggaga tgtttttaag gaaaatgaat tatctaagtt
     2701 aaaaggaaat atagggattg gacatgttag atattcaaca gctggaggaa gtcatgtttc
     2761 taattgtcaa cctttagttg gaagttgtag aaaaagacaa ttagccatag ctcataatgg
     2821 aaatctagtt aatgcaaatt atttaaaaga tatgctagaa gaagatggat atatgttcca
     2881 aactaattca gatacagaag tgattttata tatacttgct agatattaca aaggggatat
     2941 agtagaaagt ttaaaagtga caatggatta tataaaaggt gcatatgctc ttgtaataat
     3001 gagtcaagaa gaattggttg cagttagaga cccacatgga ttcagacctc ttgtacttgg
     3061 taaaaagggt gatgaatata tatttgcatc agaaaattgt gcaatagata tacttggcgg
     3121 agaagttata agagatgtag agccaggaga gataatagta gtcaaagatg gagaactaaa
     3181 atcatatttt tattcagaaa attataaacc agttaagaaa agttgtatat ttgaacacat
     3241 atactttgca agaaatgatg caactataga caatgtaaat gcatatgaat ttagaattaa
     3301 atgtggtgag agattagctc agaatgaaac tgtaaaggca gatatggtag ttccagttcc
     3361 agattcaggt tggccaggag ctattggtta tgcaaatgct agtggattaa aaataagtga
     3421 aggcttagtt aaaaatagat atgtaggaag aacatttata aaacctacac aagaagaaag
     3481 agaaatagca gtaaaaataa aattaaatcc tctttcaaca ataataaaag gaaaatctat
     3541 aattttagta gacgactcaa ttgtaagagg aactacatct aaacaattag taaaatcttt
     3601 aagagaagca ggtgcaaaag aaattcatct tagaataact tctcctccag tagcttactc
     3661 ttgttactat ggaatagata ctccaaatcg ctctaaatta attgcatcaa gtaacaacgt
     3721 agaagaaatg agagaatata ttggatgtga tagtttaaaa ttcctagata tagaaggaat
     3781 gttagatgca acagaacata agtctacttt ctgtaaagct tgttttgatg gagaataccc
     3841 agttaagaaa attgataagg aggaactact ttcatgttaa catataaaga atcaggtgta
     3901 gatatagatg aaggaaatag agcagtagac cttataaaag gtaaaataaa aggaacttat
     3961 gatggaaatg tagttggaga tttaggtaac ttcagtggat tatacagttt aaaagatttt
     4021 gtaggtatga aagaaccagt tttgcttgca tctacagatg gtgttgggac taagttaaaa
     4081 atagctcaga tgatggacaa gcatgatact gttggaatag atttagttgc aatgtgcgtg
     4141 aatgatttaa tttgtcaagg agcaaaacca ttattcttcc ttgactatat agctcttggg
     4201 aaattagtgc ctgagcatat agaaaaaata gttggtggaa ttgcagatgg ttgcaaaatg
     4261 tctggttgtg cactaattgg tggagaaact gctgaaatgc ctggaatgta tggagaagat
     4321 gactatgatt tagcaggatt ttctgtggga atagcagaca aagaaaagat tgtttctgga
     4381 aacaatgtta aatcaggaga tgtattggtt ggtatatctt caagtggagt acacagcaat
     4441 ggattttctt ttataagaaa gatattttta gaaacttaca attataaaat ggaacgatat
     4501 gttgaagaac taggaatgac agttggagaa gcacttttaa caccaactaa aatatatgtt
     4561 aaattagctt tagatgtatt agctaaacat gacataaaag ctgtagctca cataactggt
     4621 ggagggctta tagaaaatat aacaagagtt atacctaaag gattaggact agatatcaat
     4681 aaaaaatctt gggagaagcc tcctatattt aaaatgatag aaggttttaa tgctgttgat
     4741 gagagagaac ttcataagag ttttaacatg ggtattgggc tagttttaat agtagataaa
     4801 gaaaatgctg atgatgttgt aaactttata aataatagag aaaatgacaa tgctgattat
     4861 gtagataaaa aatatagtga attattagaa gataaagctt atataattgg tgaagtagta
     4921 gatagtcatg aaggtgtaga attatgctaa atataggagt tttaatatct ggtgggggaa
     4981 caaatttaca agcagttata gatggtactg agtctggaga aataaaaggt caggttaaag
     5041 tagttatctc aagtaagcaa ggtgcttatg ggctagagag agctaaaaat cataacataa
     5101 aagcaatttg tgaaactgat gaagacaaga taatagaaat tcttaaggaa aataaaatag
     5161 atttagtagt tttggctggt tatttaaaaa taatcagccc aaagctggtt aatgagttta
     5221 gaaacaaaat gataaacata catccatcat taattccttc attttgtgga gctggattct
     5281 atggagaaaa agttcatcaa ggtgttatag attacggagc taaagtaact ggtgctacag
     5341 ttcattttgt tgatgaaggt gctgatactg gaccaatcat aatgcaagat gtagttaagg
     5401 taaatcaaga tgatgatgca aagacacttg caaaaagagt gttagaagtt gaacatagga
     5461 ttttaaaaga aagtataagt cttttttgtg aaaataaatt aaaacttcaa ggtaggagag
     5521 tgtttataaa tgagtaagag agctttaata agtgtaactg acaagactgg tgtagtggaa
     5581 tttgctaaag agttaaataa attagattat gaaattatat ctacaggaaa tacatttaaa
     5641 acattaaaag aaaatggtgt taatgtaatg caagttgaag atgttacaaa ttttccagaa
     5701 atattagatg gaagagtaaa aacattaaat ccatatatac atggtggtat actttataaa
     5761 agagataaag aatctcatgt agaaactgta aatgaacata aaatacattc aatagattta
     5821 gtagctgtaa atctatatga ttttgaagga actttaaaag ctggaaaaag tcatgatgaa
     5881 ataattgaaa atatagatat tggtggacca tctatgatac gttctgctgc caaaaactat
     5941 aaggatgtaa tagtagtagt agatataaaa gattatgatt ctataataga aaaattaaaa
     6001 acagatacaa tgacattaga agacagaaaa aaattatcat ataaagcttt ctcaactaca
     6061 ggaagatatg atgcgttaat atctagttat tttgctggag aagttggaga tacgtatcct
     6121 gacatattaa atttaacttt ccaaaaagaa caaactttaa gatatggaga aaatccacat
     6181 caaaatggtt tcttatattc acagtcaaat gcaaaaaatc caatcttaaa ttatgagcaa
     6241 ttaggcggta aagaactttc ttttaacaac ttaaatgatt tacatggatg tttagaagta
     6301 atgagagaat ttaaagatag tgaagaagta gtttcagtag ctataaaaca tgctaattca
     6361 tgtggggtag gtttaggaaa agatgctttt gaagcatata caaaatgtta tgaagcggat
     6421 aaggtttcaa tatttggagg aatagtagga ataacttcta ctatagataa agctacagca
     6481 gagaaattaa atgaaatatt cttagaaata gtagtagcat atgattttga accagaagct
     6541 ttagagatac ttaaacaaaa gaaaaatcta agaatattaa aattagctaa aatagaaaat
     6601 agtttacaac catatgaaat gaaatattta gatggaaaat tattgataca agatagaaac
     6661 aatatattag cagaaaaaag tgaaaatgta acaaaggaaa aaccaacaga tgcacaactt
     6721 aaggacatgg aatttggtat gagagtagta aaaaatatga aatcaaatgc aattgcaata
     6781 gtaaaaaatg gacaaactct agctttaggt tgtggacaaa catcaagaat ttgggcatta
     6841 aaaaatgctc ttgaaaataa caaagataaa gattttacag gagctgtttt agcgtcagac
     6901 gcatttttcc catttgatga ttgtgtaaca ttagctcatg aatatggaat atcagcagta
     6961 gttcaaccag gtggctctat aaaagataaa gattcaatag aagcttgtga caagtatgat
     7021 atggttatgg tatttacagg aataagacac ttcaaacact aaggaggata ttatgaagat
     7081 attggttgta ggcggtggcg gaagagagca tgctatatgc tggaaactaa gcaaagaaaa
     7141 aaatgtagaa aaaatttatt gtgcaccagg taatgcagga attgcaaacg tagcagaatg
     7201 tgtaaatata ggtgatacta atatagaaga acttttaaaa tttgccaaag aaaatgaaat
     7261 aggtctgaca atagtaggac cagaagtacc actagttatg ggaatagtag atgagtttga
     7321 aaaagaagga ttaagagtat ttggacctaa taaaaaatgt gctcaacttg aaggaagtaa
     7381 agctttttca aaagaattta tgataaaaca taacatacct actgcaaaat ataaagaata
     7441 tacaaactta gaagaagcta tatcagaaat agatagtttt ggatatccag tagtaataaa
     7501 agcggacgga ttagctgctg gaaaaggtgt tgtaatacct gaaaatagag aagatgctat
     7561 agcaacttta aaagaaatga tgtcagataa gaagtttgga gctgctggag ataaaatagt
     7621 aattgaagag tttttaaaag gaatagaaac ttcaattcta gcatttgtag ataatgatac
     7681 aatagttcct atggcaagtg caaaagacca taaaaaagta aacaactatg agcaaggtcc
     7741 aaacactggg ggaatgggaa ctttttcacc tagtgaaata tatacagaag aattagcaaa
     7801 taaagtaaaa gagacagtat tagaaaaaac tttagaaggc ttcaaaaaag atggacttaa
     7861 ttttaaaggt attttatttg ttggtcttat gataactgaa gatggagaaa aagtacttga
     7921 atataatgta agatttggag accctgagac acaatctgtt ttatttagat tagaaacaga
     7981 tttacatgag ataatggaag ctatactaga taataagtta aaagatatag aaataaacta
     8041 tagtgatgat gaagctgtat gtgttatgct tacatcagga gggtatccag acagttatga
     8101 aaaagggaaa attataactg gtcttgaaaa cttggatgat gatatagtag tattccatag
     8161 tggcactaag atgtttgatg gtaatttggt taccaatgga ggaagagtaa ttggtataac
     8221 tgcaaagtca actacagtta aggatgcagc agaaaaagtt tatgaaaaca taaagaagat
     8281 aaactttgaa ggaatgcact atagaacaga cataggaaga taatttttct aaaatggagg
     8341 ataaggtatg ttgaatactg aaaataaaga ctcaatggtt agaagagtat tagttgaaaa
     8401 aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa gacttagtag aaagtttaca
     8461 catagataat atagaaaatt taagaatatt aaatagatat gatgtagaag gaatatcaga
     8521 agaagtttat gaaaatgcag caaagacaat attctctgaa ccaaatttag atgtagtata
     8581 ttatgaagaa ataccaaaat taaatgatga aagagtattt gcaatagaat ttcttcctgg
     8641 tcaatacgac caaagaggtg attgggcagc tcaatgtgta caaattgtaa atcaagggat
     8701 aagacctgct attaatacag caaaagttta tatattatca ggcaaaataa ctgatgaaga
     8761 gttttctaaa ataaaagatt actgtataaa tccagtagat agtagagaag catctttaga
     8821 aaaaccagaa acgttaaaaa tggaaactga aataccaaca acagttgaag tattagatgg
     8881 atttatagat ttagatgaaa atggattaaa aacatttgta agtgaaaaag gattagcaat
     8941 gactttagga gacttacaac acgttcaaaa atactttaaa gatacagaaa agagaaatcc
     9001 aactataaca gaaataaaag tattagatac ttattggtct gatcattgta gacatactac
     9061 ttttatgact gaaatagaaa atgtaaagat agaagatggt aagtttaatg atatagtaaa
     9121 agaagcgtat caaatgtatc ttaactcaag agacaatgta tatgtgaaca gacataaaga
     9181 tatatgttta atggatatag ccactgttgc agtaaaagaa ttaaagaaaa atgggaaatt
     9241 aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt ataaacgtag atgttgaagt
     9301 tgatggtaag atggaaaaat atctagtaat gtttaaaaat gaaactcaca accatccaac
     9361 tgaaatagaa ccatttggtg gagcagctac ttgtttagga ggagctataa gagacccatt
     9421 atcaggaaga agttatgttt atcaagcaat gcgtgttaca ggaagtgctg acccaagaac
     9481 gactttagaa gatactttac ctggaaaact tatgcaaaga aaaataacta cagaagctgc
     9541 tcatggatat agttcatatg gtaaccaaat aggtcttaca actggacaag ttgcagaagt
     9601 atatgatgaa aactttgttg caaagagaat ggaaataggt gcagttatag cagcagcacc
     9661 aaaagagaat gtagtaagag aaagacctga agcaggagat gtaatcgttc ttcttggagg
     9721 aaaaacagga agagatggct gtggaggagc aactggttca tctaaagaac atagtgaaga
     9781 gtcaatctta acttgtagtg cagaagttca aaaaggagat gctcctaacg aaagaaaaat
     9841 acaaagattc tttagaaata aagaagttgc tcaaatgata aaaagatgta atgattttgg
     9901 agcaggtgga gtttgtgttg ctataggaga gattgctgat agcttagata taaacttaga
     9961 cttagttcct aaaaaatatg atggacttga tggaactgag cttgcaattt cagagtcaca
    10021 agagcgtatg gcagtagcca taaaaaaaga aaataaagat aaatttatac aattagcagt
    10081 agaagaaaac ttagaagcta cgcatgtagc tacagtaaca gatacaggat atttaagaat
    10141 gttctggaat ggaaaagcaa ttgtagatat aaatagagag tttttagata caaacggagt
    10201 aaaacaaact actgatgttc atgttactaa agtagatgaa gaaaatacat tctttagctc
    10261 taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa gacaagttta caaaagtact
    10321 atctgacctt aatgtttgtt ctcaaaaagg attagtagag atgtttgata atacaattgg
    10381 tggtaataca gtacttatgc catttggagg aaagtatcaa gcgactccaa cacaaggtat
    10441 ggttgctaag ataccagtac ttggaggaga aactaatact tctacaataa tgacttatgg
    10501 atacaatcca aaggtaggaa aatggagccc attccatggt gccttgtatg cagtagtaga
    10561 atctgtgtgt aaattggttg ctattggagg aaattatagt acaacaagac ttacattcca
    10621 agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg ggtaaaccat tctcagcact
    10681 tttaggagca ttttatgcac aaagtaaatt tgagatacct gctataggtg gaaaagacag
    10741 tatgtctggt acatttaaag atattgaagt tccaccaaca ttagtttcat ttgctgttga
    10801 cacagtagat gcgaagaaag tagtatctcc agaatttaaa aaagcagact caaaagtagt
    10861 aatgttatgt gtaaacaagg cagaaaatga tgttgtagat tttgaggaat taaagagaaa
    10921 cttagataaa gtaagagaac ttatacatgg aaataaagtt ttatcaacat atgcattagg
    10981 atttgcaggt gtaggtgaag caataagtaa aatggctttt ggtaataaaa taggatttaa
    11041 gtttagtgaa gaggctgaaa aagcatttac agatgataaa ttatttgagg ctagttatgg
    11101 aaatatagta cttgaattag caaatgatga tttaagtatg ttagaaggat acaattatgt
    11161 tgtgcttgga agtacagtta aagaaactag tatatttatc aaaggtgaag aacttgcatt
    11221 agatgaatta tataaagcac attgtagtac tttagagcct atattcccaa ctaaaacaga
    11281 agaagtaaaa tcaaagatag aaactataag ttatatatca caaggagaag ctaaaaaatc
    11341 atcattaagt atagctactc caagagtatt tataccagca ttccctggaa caaactgtga
    11401 atatgactct gcaagagcat ttgaaagagc aggagctaat gcaagtataa gagtatttaa
    11461 gaatttaact tataaagaca tagaagattc tatagataca atagtaaacg aaataaaatc
    11521 ttctcaaata ataatgttac caggtggatt tagtgctggt gatgagccag atggttctgg
    11581 taaatttata gctactgtat ttagaaatcc tagagtgcaa gaagctataa atgaattttt
    11641 aactcaaaaa gatggactaa tgttaggtat ctgtaatgga ttccaagtat taattaaatt
    11701 agggttagtt ccatatggag aaataagagt tccaagtgaa agtgctccaa cacttactta
    11761 caataatatt ggtcgccatc aagctaagat tgctagaact agaatttcat ctaataaatc
    11821 tccttggtta gctcaaacta atgttggaga tattcataat atagcaattt ctcatggaga
    11881 aggtaagttt gttgccagtg aagatgttat gagagaatta attgctaatg gacaagtagc
    11941 aactcaatat gttgacttta ataatgaagc tacttatgat attgagttta atccaaatgg
    12001 ttcattctat gctgttgaag gtataactag tgctgatggt agagtgtttg gtaaaatggg
    12061 acattctgaa agaattggtg aggaagtata taagaatatt ataggtgaaa aagaccaaaa
    12121 gatatttgaa tctggagtta aatattttag ataaagcttt gatgtttaat tgatagctag
    12181 aatatataat ttagatattt agatttaaag agatgtaata atatgatgat aatcatttaa
    12241 tattacatct cttttttatt tatctaagaa ataataagtt caacctaagt taaaatacaa
    12301 gctgtgttat aattaattat taagtaaaat tgaatattta ttggaggaca acataattaa
    12361 tgaaaatatt aataacaggg tctaatggtc aattaggaaa agaattggtt aaccaattag
    12421 aagcaatcaa tcaaagtata aaccaaccaa aatatgttat attagctaca acaagaagtg
    12481 atttggacat atccaatcag actaatgtag ataattttat tttgcataat aaacctgatg
    12541 tagttgtaaa ctgtgcagca tatacaaagg ttgatgcatg tgaagataat atcgaaattg
    12601 catacaaaat aaatgcttta ggagtgagaa atctagcaat agcatcagaa aaagttaatg
    12661 ctaagcttat tcacatatca actgactatg tattcaatgg tttttctaaa tatccatata
    12721 gggaagacaa taaaactgaa cccaattctg tatatggaaa aagtaaactt atgggagaaa
    12781 aatttgttga acaattctca cataagtact ttatattgag aacagcatgg ttatatggta
    12841 atgggaataa ttttgtaaag accatgataa aactttcttt agaaaataaa gaggttaatg
    12901 tggttaatga ccagtttgga actccaacaa gtacagtaga cttagcaaaa attataataa
    12961 aaatcatgga aacagaacat tatggagttt atcatgctac atgtgaaggt gagtgtagtt
    13021 ggtatgattt tgccaaaaag atatttaaac taaaaaatat agatataaaa gtaaatccaa
    13081 ttaagagtaa cgaatttaaa tgtaaggctc caagaccact atattctgta ttggataatt
    13141 ttatgttgaa gttaattggt ttaaattctt ttagaaagtg ggaagaatcc attgaagaat
    13201 atttagaaag atatgatata aatgaaaagt aaatgtatta ttttgagaaa agaaaataag
    13261 atattataaa aaatataaat atttctttta tttatccgat aatcataata tgacaaaaac
    13321 aaatttaagg atggaaaaag atgaaaggaa ttattttagc aggagggtct ggtacaagac
    13381 tatatcctat aacaaaatgt atatcaaaac aaacacttcc aatatacgat aaaccaatga
    13441 tatattaccc tatgtcggtt cttatgttgg cagggataca agatatatta ataatatcta
    13501 caccaagaga tataaaagca tttgaagaat tatttggaga tggaagttca ctagggctta
    13561 acataacata tgcaattcag gagaaagcaa atggaattgc agaagcgttt ataataggag
    13621 aagaatttat aggaaatgac agagtgtctc ttgtattagg ggataatata ttttatggat
    13681 atggatttag tgaaaggttg gagaatgcag ttaaaagaaa aggagcaact atatttgggt
    13741 atcatgtaag taatccaaat tcgtttggag ttgtagaatt tgataaggat tttaatgtat
    13801 tgtcaataga agaaaaacct acagttccta aatctaatta tgctatacca ggattatatt
    13861 tttatgataa tgatgttgta gagatagcaa agctagttga accgtcagat agaggtgaat
    13921 tagaaataac ctctataaac agtgaatatc taaaacgagg aaaactaaaa gtggaacttc
    13981 taggaagagg tatggcttgg cttgatactg gtacacataa aggtctattg gatgcttcta
    14041 attatgttga agtggttcaa acaagacagg gactgtatat agcatgttta gaagagattg
    14101 catatacaaa aggatatata agtagagaac aattaatgaa actagccaag ccactgataa
    14161 aaactgaata tggtcaatat ctattaaaat tggctagtga agatatgtaa tatggtagat
    14221 aaaatttatt ataaatttta ttaagggagt ttattataat gggaaaaatc aatgttataa
    14281 agactaaaat agaaggatta tatatagtcg aaccaaatgt attttatgat gaaagaggat
    14341 attttatgga aagctataat aaaaaggatt ttatagagca gggtcttgat atgtgtttta
    14401 ttcaagataa tgagtctagc tcaagaaaag gcgttttaag aggaatgcat tttcaggtta
    14461 aatatcctca aggaaaatta gtcagagtta cagagggaga agttttcgat gttgcagttg
    14521 atttaaggaa agattcacaa acatttggga aatgggaagg tgtaatattg tctgataaga
    14581 ataaaaaaca attttatatt ccagaagggt ttgcacatgg atttttagtt ttatcagaaa
    14641 aagcagtatt tagttacaaa tgtacaaatt attattaccc agaatttgag aatggcttta
    14701 tatggaatga caagcaaata tctattgagt ggcctttaaa aggaattgaa gaaatatttt
    14761 tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat ttgtacaaga cgttaataaa
    14821 aatttattag aattaacatt taggagaaaa aatatgaaaa aaatactgat aactggagga
    14881 gcaggattta ttgggagtaa ttttatacat tatatgctta acaagtatgt agattatttt
    14941 attgttaacc tagacttgtt gacttatgct ggtaatttag agacattaat agaaatacaa
    15001 gacaattcca attataaatt tgttaaagga gatatttcaa atagggagca ggtgtataag
    15061 ctatttgaag aagaaaggtt tgatatagtt gttaactttg ctgctgaatc tcatgtagat
    15121 aggtcagttg agaatcctga tttatttatt aaaacaaaca ttataggaac acaagtactt
    15181 ttagatgcat ctataaaata tggagttaaa aggtatcatc aaatatctac agacgaagtg
    15241 tatggtgatt taccaattga tagaaaggat ttattcttta cagaacaatc ttctatcaat
    15301 ccaagttctc catattcagc ttctaaagca tcagcagatt tattggtaag ttcttattat
    15361 agaacatatg gattgttaac aactatatct aggtgttcca acaattatgg gccatatcat
    15421 tttcctgaaa aattgattcc tcttatgatt ttaaatgctt tggaaaacaa acaattgcca
    15481 gtatatggga atggggaaaa tgtaagagat tggttacatg tatatgacca ttgtactgct
    15541 atagacttaa taatacataa aggaaatata ggggagattt acaatatagg aggtcataat
    15601 gaaagaagta atctagaagt agtaaaaatg atattaaatc ttttaggtaa atctgaagag
    15661 ttaatatcct atgtaaatga tagacctggt catgatttaa gatatgctat tgatgcaact
    15721 aaaatagaga atgagttagg ttggaaggca aaatatgact ttgatttggg tataaaagaa
    15781 actgttaagt ggtatataga aaatgaatct tggtggaaag ctgttttatc agtataactt
    15841 taaaatttag aaaggggcgt tttatattga atgagataag ttcactaatt aatatattag
    15901 cattgactca attatctggt agtaatacta caaatcaatg taattgtaca tataataatt
    15961 catctggatt tgatatgatt atgatgacct tgttaaaagc attatcacaa aataatcaac
    16021 atacttctaa tagctacaat ttattgtcta attctgagaa tttatttaat gaacttgata
    16081 atgtagtaaa taataccact agtagattta tagatgttga tacaaaagat aaaaatgtaa
    16141 agttgagaat tgaaaatgct gtaaatcaag catcaaaaaa atataacgta gattcaaatc
    16201 ttataaaagc aataattaaa gttgaatcag attttaatcc aaataccgtt tcttctgctg
    16261 gtgctaaggg tcttatgcaa cttatgccag aaaactgcag agacttaggg gttacagacc
    16321 cttttaatat agaacagaat atagatgctg gaactagaca tattaaggaa tacattgata
    16381 tgtttggagg gagcatagaa atgggattga tggcatataa tggtggtcct ggaagaatga
    16441 aaagtagagg agtagaatca atctctgacc tgtataaaat gccaaaagaa acacaaaatt
    16501 atattcctaa ggttatgaaa tattatagag ggtaggcttt attatgggaa taaatataga
    16561 taagctaaac ataagtccaa gtataaatat ggaggttaaa aaactaaaag agagtaataa
    16621 attttctgac aaattaaact ctttaaaaca atcttcttca ttggaagata taaaacgaaa
    16681 tttggaaagt gtaaaaaagg caggagaaag gcttgtactt actcaaaact atggcgatat
    16741 tagtatatat aaaaatgcag taaaagaata cctaaaatct gttgtagata atatgtattc
    16801 acttgataaa aatagtagct tttgggagca tcagtattat aagaatgtaa agattgttga
    16861 tagtaaactt gaggatatga ctagtaagtt aattagtgaa gaaaaagaaa acatagatat
    16921 tgtttctact gttgacatga tacaaggctt attgatagat atgtatagat aaggttatac
    16981 aaggagaaaa attttatgaa tagcaaaaaa gaggatatat atgaattgaa ttttgggcaa
    17041 ttaatagaag aaaaatctgg tgttatagaa gaaaatcaaa atgtttttaa tgcaaaagta
    17101 aaggtagctg tttctatagg aaatacaaca gaaacaataa aaaatatatt agatttaaaa
    17161 gaaggctcta taataaaatt aagtaagaat gtggatgaaa aattagatat atatgcaaac
    17221 gatagattgt ttgcttatgg agaaagcatt attacaaatg agaagttatc tgtaagatta
    17281 tctaaaatag aagattcaga tgtaaattag cattttaaat atatcccttt agtctattct
    17341 gtatgagttt agctaagggg atatttttat aaaaaattta aaatatgtgt gaattatata
    17401 aatattttta ttttatgagc gataactaaa ttataagtat gtaattttgg aggtgaaact
    17461 atggatatta aaaatgtaag ttcaaatatt gtagtgaata attatttaaa gaatacatct
    17521 ggtataaaaa aagtggaaga ggttaaaaaa attaataaaa cagacaagat agagttatct
    17581 aaatttgcaa aggaaatggc aagtgtgtca aatatgagtg atgagaatat tagaaataaa
    17641 aaagtcgatg aaataaaaaa tgcattagaa aatggaactt acaaaataaa accaaaagaa
    17701 attgcgaaaa aaatgataga ggatatgcga ggataaagtc atgattacag acttaaaagt
    17761 tataatatat gaagaaaaaa atataattag taagatgatg gaattattaa aagaacaatt
    17821 tgattatata gttgaaaaag acttagaaaa tttaaatatg ttaaatccta aactagaaga
    17881 tattagcagg gagcttgcat ccatagaaat aaagagaaga caactttttg gtaatgatat
    17941 ttcaatgagt gaagttgttg aaaatagtaa tgatggatat ttaaaagaaa tatatacaga
    18001 cttgaaacgc attcttgctt tagctaaaaa tcaacaagaa tcaaatgatt ctctaataaa
    18061 gaaagaactt atttttacga aaaaaatgat taatttcata aaaccagctg ataagcaaac
    18121 tacaacttat aattcttatg gaaatattag aaaataaata ttaggaggag aaatatggca
    18181 ggattatttt ccattttaaa tacagctaat tcaggaatga atgcgcacca aaaagcaata
    18241 cagacaattt ctcataatat aagtaatcta gatacagacg gttattctag gcaaaggacc
    18301 gagtttgcta caaatagtcc aatgtatatg cctagtttga gtaattcaat tgcaagagga
    18361 caattaggga ctggagtaca tgtaacggat gtaacaagag ctagaaatag tttttatgat
    18421 taccaattta gggcagaagc tcataagtat ggtaagacag tttcaaaata tgattattac
    18481 aatactatag aaactatact aaacgaacca tcagactatg gaatatctgc aggtatagat
    18541 gattttttta aaggatggga gtcattatca aaggatataa atagtgacag taaaaaaagt
    18601 ctagtggtag aaaacgcatc taatttagca actttaataa gtgaaagtta taagaagctt
    18661 gataagttaa aagaagatat agattctaat atagacactg agataaaaca aataaatgac
    18721 atgttaaaaa gtcttgaaga tttaaataaa tctattgata ttatatctgg ttctggctct
    18781 acaccaaatg atttgcttga tgaaagagat agaattttag ataacttgag ttttaaacta
    18841 gactttgaaa atagtgatgt taaaaatatg cttgcagatg gtaaattaga acttaatgaa
    18901 ttaaaaaatc cagatggaac ttggaaaaca ggtatatcag ggaccttaca aggcttgttt
    18961 gaaatgcatg gtaagattga tacatataaa agcgatttaa aagatgtatc tgatggatta
    19021 gctaaacaga taaatgatgt ttataatacg tctgcaggaa taacagtaac agattttttt
    19081 ataacttcaa atgtagatgg tgaagatatt ataaagataa atccagctat aaagagtaac
    19141 ccaaatgaat taaagcttac tgctgatgaa gcttcaaaaa ttgctaagtt aaaggatgaa
    19201 aaaatagata ttggggtggc tggtggaaaa gtaagtacaa taagtgacca ctataaagcc
    19261 tttgcagaat caatcggttt agattctcaa aaagtaaatc aagatgaagc aaatcaacgt
    19321 aaaattataa ataatattga taactcaaga atgagtgttt caggtgtatc tttggatgaa
    19381 gaaatgacag agcttataaa aatacaacgt tcatatcaag ctagtgcaaa agttatgtca
    19441 acagctgtgc aactactgga tgttgtaata aatggaataa tttaatagaa gggggaattt
    19501 ataatgagag tcagtacagg tatgatgtct agcagctatc taaactcact acaagataat
    19561 ctacaaagat tggataaggt taatagacaa gttaatacaa caaaagaaat aaacaagcta
    19621 tcagataatc catataaagc aataaagata ttaaactcaa aaagtgaaat aaagactatg
    19681 gagacttatg ttgagaattg taaagataca gggaattggt tagaaactac tgatactgca
    19741 ttagatcagc ttggaaaatt attatcagac ataaagaaaa ctttggtggc aagtggtgat
    19801 ggtgcatact cagatgatga attaaagact cttagtaatg aaactaatga aaaaatgaaa
    19861 gaaattgcaa atgctttaaa tgcaacacat gaagggaagt acatattttc aggttcaaat
    19921 acgggggtac cacctgttga atgtatagat aatgctgatg gttcagtgag tttaaagttt
    19981 aattctagtc taaatcttaa taaattaaat gactctttga gtatggatat agctcaagga
    20041 ataagtgtag attataacgt taaattgagt agccttggat ttgacccaac aaaaactgac
    20101 ccatttgaag agttaaataa catatcaaaa aaattagcaa atccagatgc tgatgctata
    20161 aaagagctta caacaacttg tttgggcgat atggaacaac taatagaaaa tacagtaaat
    20221 gttaggtcta tatatgggac aaaagcaaat acagtagagg ctatgaagga aaaaaacgat
    20281 gatagtttga tacagttaaa ggatattttg tcacaaaatg aagaaataga ttatggtgaa
    20341 aaacttgttc aattaaaggc agcagagtta acttatcaag cttcactaca aacaggagga
    20401 aagttattta atgtatctat attagattac atataataaa ataacgcaga tatgatgaag
    20461 gttacattaa aaaaaggtat attaggtttt gaaaatttaa aagaatatga gcttttagat
    20521 atagaagata atgattattt aaaagaattt aattctactg aagaagaagg tataggattt
    20581 gttgttgtat ctccatttga gattatcaat gaatatgaaa tagttttaaa tcaggaaaca
    20641 atagaaaaac tagaagtgaa atctccaaag gatgttgtat tatttaatat aattactctt
    20701 ggtcagacat ttgaagaatc aactgtgaac atgaaagctc ctatagtgat aaatataaaa
    20761 actaattttg gaatgcaaat aattttacag gatgataaat attcaataag gcatccatta
    20821 ttgagaggtg ataatggatg ctagtaattt caagaaaaaa agatgaagca gtacttatag
    20881 gagaaagcat agaagtaaaa attgtaggag tagatggaaa caatgtaaaa ctagctatat
    20941 cagcgcctaa caatataagt atattaagaa aagaaatata cgaaaaagta aagagtgaga
    21001 atataaaagc tacaaataaa aatataaaaa ttttaaagtc attaaaataa taagcttgga
    21061 ggaagtaata tatgtatgga gaaaatcctt ataattctta taaacaaaat gctgttttta
    21121 tggcatcaaa ggaacaattg ttacttatgc ttgttgatgg agcagtaaaa tataccaaaa
    21181 tagccagagc agctatctta gataaaaata cacagaaagc gcatagagaa cttgtaagag
    21241 ttcaggatat atttacagaa ctaatggtta cattagacca aaatgcagga caatgggcaa
    21301 aggatatgta caaagtttat gattttgtaa gatatgaact ttcaagagcc aatattagaa
    21361 aagacatcca ggtaatagat aatgtgttac ctgtaataga acaaattaaa gatacatggc
    21421 atgaagctga taaaaaaagt aaagaagaaa gaagtaggta caaataatgg aattaaattt
    21481 agctgaatta gataagttat caaaagagga attactattg atgcttgtag atggcacagt
    21541 aaaatatacc aatatatcca aagaagctct tttaaataac gactatttga aagcacataa
    21601 tgaacttgta agagttcaaa atatatttac agaactaatg actacattag accaaaatgc
    21661 aggacaatgg gcaaaggata tgtataaagt ttatgaattt ataaaatctg aattagcaat
    21721 agctgatgaa aataaagata ttaaaataat tgatgatata ttgccaatag taaaacaaat
    21781 tagagataca tggcatgaag tttacaatca actaaaaata taattagatg gagggataaa
    21841 ggtatgtcaa gtataagtcc tataagagtt acaggtcttt caggaaattt tgatatggaa
    21901 ggcataatcg aagctagtat gattagagac aaggaaaaag ttgataaagc aaaacaagaa
    21961 caacaaatcg ttaaatggaa gcaagaaata tatagaaatg ttatacaaga atcaaaagat
    22021 ctttatgata aatatctaag cataaattct cctaatagta tagtaagtga aaaagcatac
    22081 tcttctacaa gaataaccag ttctgatgaa agtattatag tagcaaaagg ttcagctggt
    22141 gcagaaaaaa taaattatca atttgcagtt tctcaaatgg ctgaaccagc aaaatttact
    22201 attaaattaa attcaagtga acctattgtt cgacagttcc ctccaaatgc cagtggagcg
    22261 agttctttaa ctataggaga tgtaaatata ccaatatctg aacaagatac tacaagtact
    22321 attgtaagta agataaactc cctttgcgca gataatgata taaaggcttc ttatagtgag
    22381 atgacaggtg aattgattat ttcaagaaaa cagactggtt cgtcatcaga cattaattta
    22441 agagtaattg gaaatgacaa tttagctcag caaattgcta atgataatgg tatcacattt
    22501 ataaatgatg ctggtggaaa caaagtggca aatgtatatg gaaagaatct agaagctgat
    22561 gtaactgatg aacatggaag agtaactcat ataagtaaag aacaaaattc atttaatata
    22621 gataatattg actataatgt aaattcaaaa ggaactgcaa agttgacttc tgtcactgat
    22681 actgaagaag ctgttaaaaa tatgcaagca tttgtggatg attataataa actgatggac
    22741 aaggtctatg gtttagttac tactaaaaaa ccaaaagatt atccgcctct tacagatgcc
    22801 caaaaagaag atatgacaac tgaagaaata gaaaaatggg aaaagaaagc taaagaaggt
    22861 atacttagaa atgatgatga gttaagaggt tttgttgaag atattcaatc tgcatttttt
    22921 ggagatggaa aaaatattat tgcattaaga aaactaggta tcaatgaaag tgaaaattac
    22981 aataaaaaag gtcaaatatc atttaatgca gatacttttt caaaggctct tatagatgat
    23041 agtgataagg tatacaaaac actagcaggt tattcttcga attatgatga taagggaatg
    23101 tttgaaaagc taaaagatat tgtatatgaa tattctggaa gttcaacttc taaacttcct
    23161 aaaaaagcag gtatagaaaa aactgcttct gctagtgaaa atgtatattc aaaacaaatt
    23221 gcagagcaag aaagaaatat aagcaggtta gttgaaaaaa tgaatgataa agagaaaaga
    23281 ctttatgcta aatattcagc cttagaatct ttgttgaatc agtattcttc ccaaatgaat
    23341 tatttctcac aagcacaggg taattaatta tggataaatt aaaagaaaaa ttaaatttat
    23401 ataaagatat atctttacaa attataaatt tgattgaaaa ggaagaatat ataaagataa
    23461 gtattaagtt aggtgaaaga caagagatta taaatagtgt aagtgaaatt gatagaaatg
    23521 attttataca gctttataat agaatggaat taattgaaat tgatagcagg ataagagata
    23581 ttttacaagg acaattatta gaagtaaaaa aagaattaca tgagtataag cttactaaac
    23641 aagtgaacac aatgtattat aacttaaata gagaaaaagt aaatattttt aataaaaaag
    23701 tataaagtta tgtaccatct tgtccgatta tataaatgaa gaattaataa aaaagattaa
    23761 aagtagaaat gacaaggatg tcaactatac taaggagggt aaaataatga gagttaatac
    23821 aaatgtaagt gctttgatag caaataacca aatgggaaga aacgtaaatg cacaaagtaa
    23881 gtctatggag aagctatctt ctggtgttag aattaagaga gctgctgacg atgctgctgg
    23941 gcttgctata tctgagaaaa tgagagctca aataaaaggt ttagaccaag caggaagaaa
    24001 cgttcaagat ggtatatctg ttgtacaaac agcagaaggt gcattagaag aaactggtaa
    24061 catactacaa agaatgagaa ctttatcagt acaatcttca aatgaaacta atactgctga
    24121 agaaagacaa aagatagctg atgagttact acaattaaaa gatgaagttg aaagaatatc
    24181 aagctcaatt gagtttaatg gtaagaaatt acttgatgga agttctacag aaataagatt
    24241 acaagttgga gcaaactttg gaacaaatgt tgcaggaaca tctaacaaca acaatgaaat
    24301 aaaagttgct ctagtaaata cttcaagtat aatgagtaaa gcaggtataa caagttctac
    24361 aatagcaagc ttaaatgcag atggaacttc tggaacaaat gcagctaaac aaatggtatc
    24421 tagcttagat gtagctctta aagaattaaa tacatcaaga gcaaaattag gggcacaaca
    24481 aaatagacta gaatcaactc aaaacaactt aaataatact atagaaaatg ttacagcagc
    24541 tgaatcaaga ataagagata cagatgttgc ttcagaaatg gttaacttat ctaaaatgaa
    24601 tatattagtt caagcatcac agtcaatgct tgctcaagct aatcaacaac cacaaggagt
    24661 tttacaatta ttaggataaa ataattttgt atattggata tagaagaaag ggtaaggctt
    24721 tgctttactc ctttcttttt ttacaaatat acttttgaaa ggaaaattta tatgttactt
    24781 agtatagtta tgattgttaa aaatgaagaa aaaatacttg aaaaaacttt aaaatcatta
    24841 accacattaa gaaattctat agaaagtgaa cttataatag tcgatacagg ttctacagat
    24901 gatactataa aaatatctaa gaagtacacg gaaaaagtgt attttcataa ttggaataat
    24961 gatttttcta gtatgagaaa tatatcaata tcctatgcta aaggtgaatg gttacttata
    25021 ttagatgcag atgaaatact aattgattct tcaactattg taaaattttt taaagatggt
    25081 cttgataaaa aatttaattc tgcttcaata caattaaaaa atctttactc atatgataaa
    25141 aaattatatg gatattgttc agtgcttaga ctttttaaaa acgttgattt tagataccat
    25201 ggtaaagtac atgaacaacc aatatacaaa aaccctatat ttaataatgt tgctgatttt
    25261 gaacattatg gatatttgtt tgaagatgaa gaaataagat taaataaggt gaaaagaaat
    25321 gaaaaactat tatttcaaga gttaaaagag aatgataatt ctccatatac aaactatcaa
    25381 ttagggaaaa attttattat attaggaaaa tatcaggagg ctttatacta tcttgagaaa
    25441 tcttatgaat tatattctaa actagaattg gcacctggtt acttgataac aagccttgta
    25501 aaaacatatt tatatttagg aaaacataag aagtgtgaaa gattgtgctt aaagtatatt
    25561 aagaaagaca tgaataatat tgatatatat tattatattg cacaagcaca agtagattta
    25621 ggaaagtatg aaaatagtat agattcgtat aagagatata tttacttgtt agataattat
    25681 gaaataagta cacaagcaaa tagtttattt tcagacactg atactgtagg gcttagagat
    25741 gaggctatta ttacactgat aaagatttat tataagcttg aaaaatatga gtttgtaatt
    25801 tcagagtata ataacattga agatgtggaa aagaaaaaga atgtgtactt tagcttattt
    25861 atgtcactat ataaattgaa tagatttgaa gatataaaaa attattataa agaagtttca
    25921 aattctaaaa ttgaaaaaaa tagtttttat agaaatatag aagaagttat aaataatatt
    25981 aaagaggatg aaaaagagta tgtatataaa atcctttgtg acattgaagg taattatggc
    26041 attttaaatc aaataaggat aaataaatgt gtatctatag ataaatgtaa agaaatactc
    26101 aatgaagaaa aggaaataat ttatgcatat attataaaaa tagcttttga agagaagatt
    26161 gatttactag atatttttta tgaaatggaa tatgtatgga tagagaaata tctaaaatat
    26221 cttttagcat tagaaagaag ttttaattta gtactatata agtacataat tagtcgtcca
    26281 aatacatcag atatggaaaa gataagagta tataaagcta tatctaaagt agttttagaa
    26341 agtataagct taagtgatga aaaatataag gagatttttt atctttatat aatgtattct
    26401 tataagtaca taagatacat atatagcaat ttaagtgatt ttgaattaat aaaatttgtt
    26461 tgtaatgatt tagataagtt cactatagaa tttaagcatc tacttgatat taaaaataaa
    26521 gtaaataatg ctaatgaaaa attagagtat atacatagta tgaggaaatt actaaatgag
    26581 tatccttttt ataataaaat aataaaaata cttataggtg aattagaaga aaatataaaa
    26641 gaaagtgaag aatttaagga tttaaaagat agttttatta ttagtataga aaatatgatt
    26701 gaaactggca aaataaatga tgcgaaatta ttggtagatg actattcaaa aacatttgtg
    26761 gatgatataa agattttaaa tataaaggga attttataca tgtttgaaaa taagcttgat
    26821 aaagctgatt ttatgttaaa aaaggcatta tcattagatg tagaaaatga agatactata
    26881 tataatatag aatacttaaa aagtttaaga taagtcaaaa ataggagaat tgaagaatga
    26941 atataccaat agtggttaat gaaaaatcta aagacataat aaaagattgg caatatacat
    27001 gtacaaatga agatataaaa tttacaagca taataatatt gacatataat caaatagaat
    27061 atactaaatt atgtattgaa agtattagga aatttacccc aaagaataaa tatgaaataa
    27121 taataattga taataactct tctgatggaa cagttgagtg gttaaaggga caatctgata
    27181 taaaatctgt gtataataac aaaaacttag gatttccaaa aggatgcaat caaggtattg
    27241 agttagctac tggtgaaaac atattgttgt taaataatga tgtaatagtt actccaaatt
    27301 ggctctataa tttgaataaa gctttatggt ctcaagataa tataggtgct gtaggaccta
    27361 ttacgaatgc atgttcatat tatcagcaaa ttgatgttga ttataagtca attgaggaca
    27421 tgtttatatt tgcacacaaa ataaataaat ctaatattaa cctatggaaa tatagattga
    27481 agttagttgg attttgcatg ttaataaaaa aaactgttct ggataatgta ggggttttag
    27541 atgaattatt cacacctgga aattttgaag atgatgattt atcttttagg atgatagagt
    27601 caggatataa gttattatta tgccaggata cttttataca ccattttgga agtgtgtctt
    27661 ttaaagaaaa tcgtaataaa tatacagata taatgtatat taatagaaga aaatttgaaa
    27721 ctaagtgggg atttaatcca gaatatagtg gaatgataag aacagatttg atttctaaaa
    27781 tagatgatag tttggaggca aatattaatg ttttagaaat aggatgcggt ataggggcta
    27841 ctcttttaga aataaaaaat atatataaaa atgcatcaat atatggaata gaaattagtg
    27901 agtcagcagg taaacttgca aagtatagtg cagatgtact tatagcaaat atagaaaaag
    27961 taaaattgga ttataaaaaa gatttttttg attatataat attgggagat gtacttgaac
    28021 atttgattga cccatggaag atagtcaatg aattgaaaca atatctaaag aaggatggtt
    28081 atctggtatc tagtatacca aatattatgc atgtttctgt tttaagaaat cttgtgttag
    28141 gtaattttac atatgaagat tcaggaattt tggacaagac tcatttaagg ttttttacat
    28201 taaatgagat aacaaaaatg tttaatgata gtaattacat aattaatagt attacagcta
    28261 ctagtatgcc actttcggaa attgataata gcttcattga tacaatatgt aaggaaagct
    28321 gtaaagaaat gagacaacag tacgaatctt atcaatatat agtaaaagcc tctaaaatcc
    28381 tagatactaa aagatattct agtattagta tgattaattt aaaatacgct ttaatgagaa
    28441 ttgataatga attagatgta gatagtaatt taagttatat atttgataat tataatataa
    28501 ctgaaccatg ttttgttgat gatattgaat atctaattga tacatttgtg ataaataaag
    28561 caactctatt aaatagatta ggagttgagg catttaacag aggtctagga gattttagta
    28621 taaacatgtt tatgacagta ttagagatgg atagagatga tattgactca atatataata
    28681 taacaagtgt attatgtgaa ttagaagaat ttgatactgc ttataattta attaaaaata
    28741 gtagcgaaaa agtacagagt gaaagtgata tacaagagat actttgtttt attgagggga
    28801 agaaatatga ataatgataa gatatgtttt ataacctgtg taaatgatga aaggctttat
    28861 gaagaatgtc ttgtatatat aaatagccta gacattccta aaaactttag tatagaaaca
    28921 gtagctttaa gaggagccga ttctattgcc tctgcttata ataaagctat gagagaaaca
    28981 gattctaagt ataaggtata cttacatcaa gatactttta taattaataa aaatttcata
    29041 catgatattt tagagatatt taaaaaaaat acagatgtcg gaatgattgg tgtagctgga
    29101 gtaaaagata tgcctgtgaa tggaatttgg tgggattctg ataaaaaagc agggaaagta
    29161 tatgatagtc atacaggtaa aatggatatt tatgaattta gtaactttga agaatgtttt
    29221 aatgaagtta tggctataga tggattaatt atgattactc aatatgatgt attttggaga
    29281 gaggataagt ttgatgggtg gcatttttat gatttgtcac agagtatgga gtttagacaa
    29341 aataaataca aagttattgt accaaaacaa aataagcctt ggtgtatgca tgattctgga
    29401 gtagtaaata taaataatgg atatgatgaa tataggataa aatttgtaaa agagtacata
    29461 aatcttgatt tatatagaga aaatttttat gaatttgata agaagaaagc aagtaccata
    29521 cttaagagta ataagcatgt aatggattgt atgaaagagg agcttacaga acaattaaga
    29581 ttaaagaatt acaaggatgt tttaggtatt gtttctaaaa ttgctcattt ttctgttttt
    29641 aatcatactg gtttgtattc ttgtgaagaa tgtgagagag cattgctaga atgtgcaaat
    29701 aatttaccag aaatagaaaa tacgaaatta tttacaaaaa aagatttaaa aagaagaaaa
    29761 gtattacatg ttttaagtga aggatattca acaggaggtc atacaagact agttaaaaat
    29821 tggattgaaa ttgacaaaga ctctgttcat tcagttgtaa ctacatggca atcagataca
    29881 ctgccagact ggttattaaa agcaataaat gatagtggtg gcgaagttat atctttggat
    29941 ttaatttcag atgattattt aaaaagagct gtagctttga ggaaaatagc ttatgactgg
    30001 gctgatatag ttattttata tgttcatatg tgggatacaa tacctgttgt tgcttttgga
    30061 gttgatggga aaatacctat tttacatgtt aatcactatg atagtacttt ttggttaggg
    30121 acaagtattg cagatattgt cattgatttt agcgaagcta gtcaattaat tacattagat
    30181 aaaagaggca tagataaatc tgaaatatta ccaatgccat taaaagaaaa agaagtattt
    30241 tcaaaatctg aagttagaaa acgatataat ttagaggatg atgtgacaat aatattgact
    30301 attgctagtg aaagaaaata caatagtgta aatgatatta attactttaa aattgctaaa
    30361 acattgattg aaaatacaga taatacaatt attattgttg taggagttga tacagagaat
    30421 ctctattgga aaactttaag taacgttaca gataatagag ttatatgttt tggaacaaca
    30481 gcaaatatag acgattttta caagatttcg gatatatata tggagtcttt catggtagga
    30541 agtcatactt caaaactaga tgcaatttta tatgatttaa ttcctgttaa gtttaaaaat
    30601 gaagtttcac caatttttac aaatatgtgg aattttatag ataagtttga ttataagaat
    30661 ataaaagagg ttatagatat gataaaaagg tacaatacta gtgaatttga cagggatagg
    30721 ataaaagaaa aacaatcgga aataaaacat tttgttatag ataaacactg tattgaaata
    30781 aaaaactata tagacaaaat atataatgaa gctaatcatc ataaagttaa gtatgattta
    30841 tataaaaatg atgaaatcga ggactatcag ctttttgtag cattatatgg ctatatggta
    30901 aaaaataaaa acatgtcata ggtggtaaaa tgaacaatat tcatatcaat aaatttgaaa
    30961 aaagctgtga aagaaactgg gattattttg tagaaaataa atctataaat ggtacatttc
    31021 tgcaaactag aaatttcctt aattatcatg aggagggaaa attcactgac cactcattaa
    31081 taatatgtaa aggtgaagaa atactagcag tcgtacctgc atgtgaaact tatgaagatg
    31141 gtgaaagaat atttttttct catttaggga gtacttttgg tggtattata ataagaagtg
    31201 gttttaatga tattaggcat gtaaatgcca ttacaaataa gttagaaata tatttacggg
    31261 aacaaaattt cgataaagta tatttaaaaa atacatcaag aatattttgt aaagaggata
    31321 cttcattact agaatatttt ttatttaaga ataattacat gttttatgat gaattaagta
    31381 tgtttttaga attaagtaag tataaagaag atatattagc caattttaaa tacagtaaaa
    31441 gaagagattt taaatattct ttgaagaata atcttacctt taaaagactg tatagtgatg
    31501 aagatatagt ttgttttttt aatttacttt ctaattgttt agatagtaaa ggagctaaag
    31561 taatacattc agtagaagaa cttttggagt ttaaaaataa tagattaaaa gatattgtag
    31621 aattttatgc agtatatatt gatgacatta tgatttgtgg gagcatggta tttaactttc
    31681 aagaaagagt ttatcatact caatatctag catcaaattc gacatataat aaatattatc
    31741 caatgatatt tttatactat aatctaataa aagatgcttt agagagaaat tttaagtatc
    31801 tttcttttgg aattagcact ctaaatagag gcaaatactt agacgagggt ttagctacat
    31861 ttaaagaagg ttttggttca agtgcaattt gtaacagaac atactataaa aatataaata
    31921 agtgagaatc atgttttata gagtttttag aatatagtaa atatctagta ctctaacatt
    31981 acataaaaat aattagttta taaagaaggt ttgtatatga aaagattaat gattttaggc
    32041 tcaattaagt attttgagaa tattgttata tcagctaaaa aagagggaat atatacgatt
    32101 gtttgtgata atagaattga tactcctgcg aaaaagattt gtgatgaagc aatagatgtt
    32161 gatgtatttg attttgataa aataaaaagt atagctatag ataaaaagat agatggaatt
    32221 ttaactggat ttacagattc tttaatgaaa ccatatgttt atattgcaaa tgaactaaat
    32281 ttaccatgtg tgatttcttg caatcaactt gaatctgtaa ctaacaaggc tattatgaaa
    32341 aaatatttta aaaataatgc aatacctaca actgattact gtattattga aagtctaaaa
    32401 gatttagaaa aaatacaagg attaaatttt ccacttgtaa taaaacctgt tgatggttat
    32461 ggttcaagag gtgtatattt tgtatcaaat atagaagaat taatagaaaa atttgaatat
    32521 tctaaggaag cctcacaaga tggacaagta ataattgagg aattttatga aagtgaggaa
    32581 atacaaggac tagcttgggt tcataatgga gagtcacatg tattttatat tggagataga
    32641 gagcttgtaa acatacatac aggaagagct ggaaaaccag atagattact ttatccatca
    32701 aagtattgtt ttcaatatga ggaggaaata aaatctatat atcaaaatat aacacaggct
    32761 tttgatataa aaaatggacc tctttatgta caaatgttag tgggagcata tggaataaag
    32821 gtatctgaag taatgccaag attacctgga ggttgtgact atatggctat ttctcaaata
    32881 acagatttag acataggaag tttatttgca aactttagtg tgaataatga agtaaatttt
    32941 gatgaaataa agaaatataa tatgcatcta tcaaaatgtg tatatgcatt accaatatac
    33001 ataagacccg ggacaataaa aaagataaat aatatagata aaatagaaaa cttagattat
    33061 gtcactcaat ttctattact agtaaaagaa ggagatacaa tagaattata tgaagatgag
    33121 agacaggatt gtggaagagt ttatggaata gcaaataata tatttgatgc aaatataaaa
    33181 aagaaatgta ttcatgaaat gatagaaata cttgatgaaa ataatgaaaa tatgatagaa
    33241 aatttttaaa taagggagta tgatagatat gaagctaata actcatgaac aaattatgtc
    33301 attaaacatt tctcagaaac aaggatatga gtggataaaa gaatctttct taacaaaaaa
    33361 agattgtcaa ttaccaccaa aaataagcat ggtagaagaa ggacatgtat tttacaatgt
    33421 aatgccatcc ctaaatcata atcatatgat tggtggaata aaaatggtta caagattgcc
    33481 agggagaaat ccaagtttaa actcagagat atttctatac aatatggaag atgctaaatt
    33541 aaaggctatt ttggatggta attatattac agcttttagg actgctgctg ttgctgcctt
    33601 ggctatcgat acatttgcta aaaaagattt taatactatt gctattatgg gtttaggtgt
    33661 aactgcttct gctataatga atatgctttc atatactctt aaagataaaa atataaatat
    33721 aaagttactt aaatataaag accaagcaga gttgtttgta aaaaagtatg aaaaaaatga
    33781 acaatttagt tttgaaatat gtgatacaca tgaagaactt attgtagatt cagatgtagt
    33841 tatttctact gtgacatata cagatgaata tttatcagaa tttaaatggt ttaaaaaagg
    33901 tgctttatta ttacctgtac atgttatggg atttggaaat gttgattatc tatttgataa
    33961 agtatattta gatgattata atcatttgaa acatctagaa aatatagata gatataaata
    34021 ttcttgtgaa ttttatgatg ttttaagtaa acaagctaaa ggaagagaaa atgatgatga
    34081 gagaataata tcttacaata taggtttgtc aatacatgat atattatttg caaataaaat
    34141 ttacgaattg tgtgaaacac taagctgtga agaaatagaa ttaaaagaac caaaagaaaa
    34201 atattggata tagtttattt cattcatatt tacaatagtt tattgtaaat atgaatatga
    34261 agtaatatat tgttagaaaa ttagcatgaa taggatagat aaatttatgg ataaatataa
    34321 tttaattagg ttcgtatcta ttggaaacga atatatagga aatttagttg cattagaatc
    34381 aaataaagta ataccttttg atataaagag agtttattac atatatgatg taccaaacaa
    34441 tgtaaagaga ggatttcatg cacacaaaaa cttggaacaa gtactagttt gcctaaatgg
    34501 aagtgtgaag ataaaatgtt atgatggtgt aaaagagact atatttaatt tacataaaaa
    34561 tgatgttgga ttatatatag gaacgggagt gtggcatgag atgtttgatt ttgatgaaaa
    34621 aactgtttta atttctatag catctgaaca ttataatgaa gaagattata ttagagacta
    34681 taaagaattt ttaaagtatt taaataatgt gtagttatta tacaattagt gatgtatttt
    34741 cttaattaaa taaatttaag atagccacat agagaataga tagattagga tgtgaattta
    34801 ttgttggtta aatttaataa tttattaaaa cagttccaaa ctcataaaga agaatatgaa
    34861 cagaagatta aggatgtaat ggaaagtgga tattatatcc ttggaaatga agtaaagcat
    34921 tttgaagaag aatttgctaa ctatgtaggt agcaaatatt gtgttggttt agccagtggt
    34981 ttagatgcac tgataattgc ttttagagca ttaggaataa gcaaaggtga tgaagtaatc
    35041 gtgcaatcaa atacatatat tgctagtgtt atgggaatca gtataaatgg agcaacacca
    35101 gtatttgtag aaccaaatga atattataat atagattcat ctaagataga agaaaagata
    35161 aatagcaaaa caaaagctat attagtagtg catttatatg gtcaagcaag taatatgaaa
    35221 gatatacaag aattatgtga taagtataac ttgtatttaa ttgaagattg tgctcaatct
    35281 catggagcta aatatgatgg aaaaatgaca ggaacatttg gtgatatagg ttgttttagt
    35341 ttttatccaa gtaaaaattt gggtgcattt ggagatgcag gagctatagt aactagtaat
    35401 gaggaaatag ctgataaagt gaaaattctt agaaactatg gctcagaaaa gcgatattat
    35461 aataaatttg tcggatataa ttcaagattg gacgaaattc aggcaggttt attaagagta
    35521 aaacttaaat atctaaatga aattgaaatt gaaaaatcaa aaatcgtaga tagatatctt
    35581 aatgaaatta ataatcccaa agtcatactt ccaaagatag aaaataattg tactcatgta
    35641 tggcatttat ttgttttaca agttgaaaaa cgagatacat ttatggaata cttaaagaaa
    35701 agtggtatag agtctataat acattatccg ataccaccac atctatctga agcatatgct
    35761 tatttgggat ataaaaaggg gagttttaat atagctgaga actattcaga taaagttgtt
    35821 agtatacctt tatttattgg tatggaagat gaagaagtta gttatataat taaaattata
    35881 aatgaatatt a
//
LOCUS       DAMJWC010000041        34818 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMJWC010000041 DAMJWC010000000
VERSION     DAMJWC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34818
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.041"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC503_002281"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="PC503_002281"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF2528253.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKAYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="PC503_002282"
     CDS             complement(2851..3216)
                     /locus_tag="PC503_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528254.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="PC503_002283"
     CDS             3415..4263
                     /locus_tag="PC503_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528255.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGIPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="PC503_002284"
     CDS             complement(4700..5788)
                     /locus_tag="PC503_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528256.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="PC503_002285"
     CDS             5913..6641
                     /locus_tag="PC503_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2528257.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6843..7334)
                     /locus_tag="PC503_002286"
     CDS             complement(6843..7334)
                     /locus_tag="PC503_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528258.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7345..7788)
                     /locus_tag="PC503_002287"
     CDS             complement(7345..7788)
                     /locus_tag="PC503_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528259.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7778..8617)
                     /locus_tag="PC503_002288"
     CDS             complement(7778..8617)
                     /locus_tag="PC503_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528260.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8836..10221)
                     /locus_tag="PC503_002289"
     CDS             complement(8836..10221)
                     /locus_tag="PC503_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528261.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDSLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10394..11137)
                     /locus_tag="PC503_002290"
     CDS             complement(10394..11137)
                     /locus_tag="PC503_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF2528262.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSKHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11157..12419)
                     /locus_tag="PC503_002291"
     CDS             complement(11157..12419)
                     /locus_tag="PC503_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2528263.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12603..13601)
                     /locus_tag="PC503_002292"
     CDS             complement(12603..13601)
                     /locus_tag="PC503_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF2528264.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13585..15096)
                     /locus_tag="PC503_002293"
     CDS             complement(13585..15096)
                     /locus_tag="PC503_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2528265.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15150..16112)
                     /locus_tag="PC503_002294"
     CDS             complement(15150..16112)
                     /locus_tag="PC503_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2528266.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC503_002295"
     CDS             complement(16160..17050)
                     /gene="rbsK"
                     /locus_tag="PC503_002295"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF2528267.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17092..18105)
                     /locus_tag="PC503_002296"
     CDS             complement(17092..18105)
                     /locus_tag="PC503_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2528268.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="PC503_002297"
     CDS             complement(18334..19311)
                     /gene="bioB"
                     /locus_tag="PC503_002297"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF2528269.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19517..19780)
                     /locus_tag="PC503_002298"
     CDS             complement(19517..19780)
                     /locus_tag="PC503_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528270.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19850..20923)
                     /locus_tag="PC503_002299"
     CDS             complement(19850..20923)
                     /locus_tag="PC503_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2528271.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21171..21929)
                     /locus_tag="PC503_002300"
     CDS             complement(21171..21929)
                     /locus_tag="PC503_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528272.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTIYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            complement(21926..22843)
                     /locus_tag="PC503_002301"
     CDS             complement(21926..22843)
                     /locus_tag="PC503_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528273.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22843..23043)
                     /locus_tag="PC503_002302"
     CDS             complement(22843..23043)
                     /locus_tag="PC503_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF2528274.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23048..24142)
                     /locus_tag="PC503_002303"
     CDS             complement(23048..24142)
                     /locus_tag="PC503_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528275.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24652..24792)
                     /locus_tag="PC503_002304"
     CDS             complement(24652..24792)
                     /locus_tag="PC503_002304"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF2528276.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            complement(25102..26409)
                     /locus_tag="PC503_002305"
     CDS             complement(25102..26409)
                     /locus_tag="PC503_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2528277.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26474..26953)
                     /locus_tag="PC503_002306"
     CDS             complement(26474..26953)
                     /locus_tag="PC503_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF2528278.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27000..27863)
                     /locus_tag="PC503_002307"
     CDS             complement(27000..27863)
                     /locus_tag="PC503_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2528279.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27863..28618)
                     /locus_tag="PC503_002308"
     CDS             complement(27863..28618)
                     /locus_tag="PC503_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2528280.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28645..29133)
                     /locus_tag="PC503_002309"
     CDS             complement(28645..29133)
                     /locus_tag="PC503_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2528281.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29151..29552)
                     /locus_tag="PC503_002310"
     CDS             complement(29151..29552)
                     /locus_tag="PC503_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2528282.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29555..30052)
                     /locus_tag="PC503_002311"
     CDS             complement(29555..30052)
                     /locus_tag="PC503_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2528283.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30076..30480)
                     /locus_tag="PC503_002312"
     CDS             complement(30076..30480)
                     /locus_tag="PC503_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2528284.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30710..33277)
                     /locus_tag="PC503_002313"
     CDS             complement(30710..33277)
                     /locus_tag="PC503_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2528285.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33443..34186
                     /locus_tag="PC503_002314"
     CDS             33443..34186
                     /locus_tag="PC503_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2528286.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            complement(34498..34704)
                     /locus_tag="PC503_002315"
     CDS             complement(34498..34704)
                     /locus_tag="PC503_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528287.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
BASE COUNT        11273 a         6375 c         3556 g        13614 t
ORIGIN      
        1 cttaaaaata attcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaatgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatgcttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaagaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctcgaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgctaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggctctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcattcc taacaatgtt cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggta tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctatac aaggtatacc acaggctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtattgg tgggtcagaa
     4501 tagtatgata ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gccaaaaaat
     6301 ataatgtaac cgatttttta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aataacctat aaaagaactg
     6901 taaacatagt catatactat aaaggctatc tcaaatgaac ctataataaa tatgtttatt
     6961 ggaatataaa ctattgttct taataaaaaa tacaatataa gtatcattat atttgcaaat
     7021 actaatttca taaaatactc aatatatata gacctatctt tttctataag atattttaca
     7081 ataccatata ttccaaaggt aagtgaatat acaatccatt gagacttact tgccatcact
     7141 ataaatccta aaactataga acctatataa aaagcaattc cactcttaaa gccccattcc
     7201 attattacaa ttgatactaa aagtgatgct aaccccataa taaacaatgt atttacagga
     7261 ataatatttg taagagtcaa caatatcaca tttaatgcta ataaaactcc tccataagca
     7321 acttttatac tcatatttat catcctaaca acaagttatt aaatctccac caaaacattc
     7381 acaacatgaa tctaaacacc aaagcttagc acaattttca caacaatcgt cacctagaca
     7441 acaacagcaa tcatcacagc aacagcaaca acatccatct aaatcattac gtcttcttct
     7501 attataattg tcagccctat tgctataatc atttctatat tgtgtataac ttctaagtgc
     7561 atcactatat tcactatttt caggctccat aaattttgct ctttttaaga agtcttcacc
     7621 ttcttcataa tatcctatgt tcattgcaga aaagccagtt aaataatacc actctgcaca
     7681 tttgtcagtc aaagttttta aaaaatcata tgctttttta aattcactat tttctatgaa
     7741 tgctcttgct ctcataaaat tttcattatt ataagtatta ctgtacattc tttccacctc
     7801 tactttctaa tatattaata tatcttaaat aaacaccaga ataaattata ttttctatta
     7861 ttccaacatt tttatttaga tttagattat caattcccct agctaaaaac cctaatgatg
     7921 ttactattat tttttttact ttttctttta actcatcatt tttatcaata tactctataa
     7981 atggattata tcttcctttc ttaaaatctt catctaaatc ttcataggca tctagtagat
     8041 atatatactt acctatatta aaacctatca ttcttaagtt tctctcattt tcatcttttt
     8101 tatagacaaa tacttcaccc attatatttc caaatatact agatacttca tctatattta
     8161 tatttttatc tttttctaac ttatttaatt catttagttg ttgttttata tactctgctt
     8221 tttcaggata cttttcatat gctaatttta atttgttttt atatatataa tatgccaatt
     8281 tatcttttat gcgtttatca tccattaaat tatcttccaa tttataatac gttaaaagaa
     8341 tattcatact tgctgcatat tctgtaatat catttgtaat tacctttttc tttttaaatg
     8401 gatttactat acacacttcc tctgtactta tagactctgg gttatatact gctgttaata
     8461 aaacaattaa aaatgttata tcataattca aagaaaacct agagatttct ccatgatttc
     8521 tttttaaata tttacatagt ccacaatagt aagctttgta ataatcgtat tctctaaatg
     8581 ttaaatccat tttgtttatt ttaacatatc caaacataaa tactcctttt tgtactattt
     8641 tttatttaga ttatatatag tataacactt tttatcaaga ttatataatt tacagtattc
     8701 taagaaactt aaaaaattcc ttctaatcat tgtatcttaa atttaaaata attagaaggt
     8761 tgggttaaaa ataatattaa attatatact tatattaact catacaagtt agttgtgctt
     8821 atatcaattt aagttttaaa taattggtat atatttaaaa ctacctacag tatccttcaa
     8881 ttcttttttt gctttattta taaccaattc atcaagcatt acatcattta ttgaacatga
     8941 tatagattta gatgccaata acattgcttt aaatcccata tcagaacctg cactggcaca
     9001 agattgccat gtatgggcag aaataccaat aggccaaact gaacaagaac actgtgctgt
     9061 aggaattatg taactaacat ctccaatatc caatgataat gatatacagt tattatgagt
     9121 aaatgtatca tccgtaactt catcatgcag attcatctta gtaatatcct tatttccact
     9181 taatacacta gaaacactac ttcttttatc tatagacact gtctcagcta atttatctgc
     9241 aaaatagtag tcatcttcat tatagttttg tacacctact aatttcatat tttgtgatag
     9301 aatatctgtt aatattgtat ttggaatata gtcatatact ccacttataa tgtcatattc
     9361 cataatagta ccagtcatta atgctgctcc ttttgctata tcaacaatcc taccaaatac
     9421 atctcttaca tgctccattt taactcctct tatgtaatac cacacttctg caaaatcagg
     9481 aactatattt ggcatttttc caccattagt agttacatag tgtactctac aattatcaaa
     9541 tatatgttct ctcaaataat tacaacctat attcataagt tctactgcat caagtgcact
     9601 tcttccgtta taaggagctt gtgctgcatg ggcactaatc ccattatatc taaatttcac
     9661 agagtaatta gcaagtgttg ggattcttat aggagtattt atatcaaatg gatgccaact
     9721 aaaagcacaa tcaattccat caaaaaaacc tttttttatc atcaatactt ttccagataa
     9781 atcttcctct gctggacatc catagtattt tatagtccct ttcagctttt ttagtttgat
     9841 taattccttt actgcaatta cagctcctat tgaacctgta cccagtaagt tatgtccaca
     9901 tccatgacct gcaccaccat ctacaatagg ttctttaata gtggatactt tttgagacaa
     9961 actatctaaa gcatcatatt ctcccaaaac tgctataact ggtctacctt ctccatagct
    10021 agccgcaaat gctgtatcca taccttctaa ttcatctata ctaaaaccat atttttttaa
    10081 gtattctttt tgtaaatttg aagcataata ttctttatac tgaagttctg gatttttcca
    10141 tatcttatct gatatatctc ttaattctcc ctgtatctca tctatatatt ccatcaaaaa
    10201 ctttttattt aaattctcca tattaattat ataaacctcc ctgtttctaa taacttatcg
    10261 attatcagcc aaaatgacta attttaactg atttaaaaat attttctatc atacaaccat
    10321 tttatacaat aaaacctctt gacttgtaag tttcatttta tcaagtaaga ggttttcaag
    10381 ttttataaaa tttttagcat gttaaccaat caagcatatt aacccataat ttattatagt
    10441 atttccaatc agtaaattct tttggacccc agtgaggtgc acagtcagaa ctaaagatag
    10501 cagattttcc ttttccaaac tcgccaacag ctacaaatgg gtctcctcca atagttgcta
    10561 aaacaggaca attatctcta gctactgttt tgttatatcc taaaaacttt ggccattctg
    10621 ttggtatacc ttttaatact ggatgtttag agtcaataac ttctggaatt attcctgctg
    10681 gtttttcaac tctatcatct ttatctatca ttgttattgg taatacatct ttgatagcag
    10741 tttctccgaa tctagctttt gcatctattc ctgtaaatga catatatcca cctaccatga
    10801 ttaacgcccc accattattt acatactctt tgattagttc aagtctatct ggattactat
    10861 tgcaatctat aaaagtacta ttagataata agaacgtatt agaacctata tcagataata
    10921 ttatacagtc atactcattt aactcttcta atttatacgg aaaactatct gctgctacat
    10981 gtgcaggcat atgaactgtc tcatatcctc cagattctat tgcttctttc aaccacttta
    11041 cagcttcttc ataatgagtt gtaacaaacg tatcaaatcc ttttatatga gttatatttt
    11101 ttacccaaga ttcccctact attaatactt ttttcattta tatattcctc ctacttttat
    11161 aagtttaata ttagacttgc atacataagt atactatcta aatactcctt aatttcaaca
    11221 tattcatcaa ttgaatgaca ttgttctatt gaacctggcc ctaatataag tgttggtatt
    11281 tcagctaaat ttttcattaa tctcgcatca ttgccagctg ttgaaccttt tatctctaat
    11341 tttttcccta gagtttcttc tagtatttta tgtgcattca ctacaaaatc agaatccttg
    11401 tccatctcaa aacctaaccc tgattgatat atgtttatat ttggtttatt atctttaagc
    11461 cataaatctc cattagccct tgtcattatg acatttgtta catcatttac aacttgttca
    11521 taactcatta tatttggcaa gaagtgtaca cataaattaa atacacactt atctggcaca
    11581 gtagaacctg ctgttccacc atttattaca cctaaattta ttgtaggtga aggtaatagt
    11641 ggatgtttat atatcataag ccagttatgt tccaactctt ttatatcttg aagcaacaac
    11701 atagccttct caattgcatt tacaccctcc cacttactac cacagtgaag agacacacct
    11761 ttaacctcaa cttcaaagaa tacaaatccc atatgtgcaa ctattaagtt ttgttctgat
    11821 ggttcacaaa ttatgcaaca atctccatca ataccattca taactgcatt tatggtacca
    11881 tttccgccac cttcttcatc tactactgac attattttta cattaccagg tacatttaga
    11941 ccactatctt ttataagctt tacagctaat attgatgcta taagtccaga tttcatatca
    12001 gcagttccaa gtccataaag ttttccatta tcttctgtag cacgatatgg attatatttc
    12061 cacttactta tatcacctgg tggcatagtg tctacatgac cattaaatac aattgtctta
    12121 ccaggtaaat catcactata cttacaaatt aaattatatc tatcttgata attgtgacct
    12181 agatttcctt ctttatatat attttttgct tttttaatta attcttcgct catttcttgt
    12241 ctatctacac taaaacctat gtaatttgca agtttttcaa tatattcctg tccttctttt
    12301 tcaaatccac ctagtattcc atgaccaaca tcttcagtct ttatacttac aagttctttt
    12361 aaataatcta tgtattcttg ttttttacta tttaatgtat ctaagagaat ttttttcata
    12421 tttcctccta agatttattt ttacatttaa aatttcaagt ctaatctcat ctatttaagc
    12481 catagtaaac tttttcactt agcatattcc cattcaatgt ataaagatgt atgcaaatta
    12541 aagtataaaa atatatacaa aaacttaata atttttatag tttataagct aaaatttaat
    12601 tactatttag atttagctga tttttttaat tttatattat ttatccatat agcaaataac
    12661 attaccaaac cttttataat catttgatta tatgaagata cacttaataa gtttaatcca
    12721 tttcctaata ttcctattat tccgacacct atacatgtac ctactataga accagaacca
    12781 cccatcatat tagtaccacc aagcacaacg gctgctatag catccaattc tgctccatct
    12841 ccaacagttg gtgaacctga tgccaaacgt gatgatagta ttatcccagc taatgctgtt
    12901 agtagtccag ctagtgcgta tacttttact ataactttat ttacttttac tccacataat
    12961 ctagcggcct cttcatttcc acctactgca tgtacatgac gtccaaaatt agttcttttt
    13021 aatagaaaat gtcctgctat tacaactata atcataatta taactggtat tggtattggt
    13081 ccaatatatc ctctaccgag catcttaaat gcatctgtat ttactgatat aggtcttcct
    13141 cctgtaaata caaagcttgc cccacttatt atcgttaaca tggctaaagt tacaatgaat
    13201 ggaggtagtt tttgtgttga aataattgca ccttttatga ctcctaaaat tgtccctatt
    13261 gctaatgcaa gtatcatacc tacccatata ggtgcattat aattcactac tgttgtagcc
    13321 caaaatgtac ctactaaagc aattactgct cctacactta aatctattcc tcctgtaatt
    13381 attacaaatg tcatacctac tgcaagtatt gcatttattg atatttgtct tccaacatta
    13441 attaaattat ctaaagttaa aaagttagat gaagctacac tcattattat aaaaattatt
    13501 acaagtccta cagctgcact cccttggtct ctaaatacac ttgttaattt tgtcaataat
    13561 ggagaagatt tttcttcttt atgcttagtt attgaactca ttaattttac ctccgaaagc
    13621 caattttaat acattatttt caaccatttc ttcaccttct aaaaatccac ttatatgacc
    13681 ttctctcata accattattc tgtcactcat tgatattaat tctggtattt cagaagatat
    13741 cattattata cttacaccac tctccactaa atctcccatt agattgtata tctctgcctt
    13801 agcatttaca tctatacctc tggttggttc atccataatc aatatatctg gttgtaataa
    13861 aagccatctt gctattatag ctttttgttg gtttccacca cttaaacttt gtataacttg
    13921 attcatatgt ggtgttttta tctttaaagc ttctatgtat ttttctaaaa tctctttttc
    13981 cttttttcta tctataattg atttaaactt agatatcttt tttaacccag ccatagttgt
    14041 attttctttg acactcattt gtaaaaacaa tccagtacct tttctatctt ctgttattaa
    14101 tcctagtcca ttttctattg catctgatgg agttttaaac tttacttctt cattgtttaa
    14161 atatattttt ccagaatcat atgttctaag tccaaatata gcttctacta tttcacttct
    14221 cttacttcca actagtccac ctattcccaa tatttcacct tttcttatat taaagctaat
    14281 atcattaaaa acattgttct tagttagatt ttccactcgc ataatttctt cttttatttc
    14341 tacttttctt tttgggaaaa attggtctag ctttctatct atcattaaat taactaattc
    14401 ttcctcagac gatacatctt tggtatttaa agtcgaaatc gttttcccat ctcgcattat
    14461 agttattctg tcacaaatct caaagagttc ttccatccta tgggatatat atattatact
    14521 aactccactc tcttttaaat catttataag tctaaaaagt atttcagtct cttttttact
    14581 tattgaagaa gtaggttcat ccattattaa tactttagtt tctgatgata aaactcttgc
    14641 tatttctacc atttgttttt gagctatact aagctctttg actaaactat ttggatttat
    14701 atctattccc atattatcga aaatcttttt agcttcttca ttcatttttt tgtcattggt
    14761 taagactttg ccatttattt cttttcccat aaaaatattt tgtgctactg ttaattcgtc
    14821 aaaaactgtt agttcttgat atatggcatt tatacctatc tttttagaga tatctgggga
    14881 tatattctct atttctttgc cttcaaaaat aaattttcca gaagttttcg aatgtgcccc
    14941 agttaaaatc tttatcattg ttgatttacc agcaccattt tcacccagta gtgcatgaac
    15001 ttcgccatga aataactcaa aattaacatt atctaatgct ctgacaccag gaaattcttt
    15061 agcaatatta cttaacttca gaattatatt actcataatg acactccttt ttaaatagga
    15121 tttctttcaa ataatctcat tttattttac taattcttaa agtcttttat attttcctta
    15181 tcataaagta aagctggtac tggtatattc ttttctacct tttccccttt tatagctttt
    15241 actactgctt ctacagctaa acgtcccatc tctttaggtt gttgttgaat catagcaaga
    15301 atagttccat ctgttattcc acttgatgct tcttcagtta agtcaaatcc tacaatctta
    15361 acatccttat tttttgcaga ttcaagtgca gctttagctc ctagtacact attttcagct
    15421 gttgcatata ttatatctac atctggatta gattgaatta agttttctac tgtattaaga
    15481 gattcttctc tgtcatatcc tggttgtgaa tttaatatct taacatttgc tgaacctttt
    15541 aatgcatctt taaatccatc tattctctgc atttgtattt gagattttaa atctgtcact
    15601 attgctattt ctgactttcc acctaacttt tcatctatgt attttttagt gtattcccct
    15661 aattttttac cagcatcata actaactgtt cctacataac ttgtaatatt ttcagtattt
    15721 aatacagcat ctactgtaac tactggcatt ttttcaaatg ctccttctac tgctggtact
    15781 atagccgaat tatcagttcc aagtactatc attccatcta cattctgttg tataaaatct
    15841 tctattgctg atgtttgctt agctacatct tggtctgggt catttactat aactttcaca
    15901 cctaattctt tagctttttc ttttattccc tcatcaatat ctataaaaaa ttgatgttga
    15961 agagttattg tagatactcc aatagttaaa tctttcttgt ctgaaccacc tttattatct
    16021 gatttacttg gtccttccat tgaacaccct gttaacattc ctattgctag tattccagca
    16081 attcctaaag ataaaatttt tctcactctc ataattaacc tccattttta atagttttaa
    16141 atttgaacaa attagatttt tatttattat ttaaatactt ttcaacatct tctttatagg
    16201 gcataccaga ttgtgcacct agtttagtta cagaaagacc tgatactact actgcatatt
    16261 ctactgctgt atataaattt ttcccttctg ttatagccac tgccaatgct ccattaaatg
    16321 tatctcctgc tcctgtggta tcttgaacat caacacttat acaagataca tgcttgattt
    16381 cctcaccatc ataaaatcta gctccatttt ttccttctgt tattacaagt ttatttggat
    16441 atttttttaa tacttcttct atcccttcat ttgtgtcaaa aactatctta tattcatgtt
    16501 catttggtgt taagtaagtt actttttcta ttatatcttc atttagtttt actgctggtg
    16561 ctggatttaa taaaacccta atcctatttt caaaacagaa attcactaca taatttattg
    16621 tttttaatgg aatctctaat tgtagcaata ctatatctgc attctttatc tcttcttcat
    16681 tctttttaat taattctata tctactagct cattagtccc tggtacaaca acaatactat
    16741 tatcattttc acataatgtt ataacagcaa caccagaact tttgtgatta tttctggata
    16801 ctaagctata atcaacttta ttcgttctaa aatttcttat taactcctct cctaagccat
    16861 cttcccctat gcatgatatc atttttacat ttgctcctag tttagaagct gagatagctt
    16921 gattagcccc ttttcctcca ggtgatgtaa aaaaactatt acctaatact gtttctcctt
    16981 tttctggtct tttatctaca gaacatacca tgtccatgtt tacacttcct atgacaacta
    17041 tatttcccat tacattactc ctttacatat ctatttatgt ctctcgtgct gttattcact
    17101 ttcttttgtt gaatctctta tgaccaattc tggtttgaaa atcaattcat caaacgattc
    17161 ttttttatct cctcttaaac aatttatcaa tatttcactg gctttatatc ctatatcata
    17221 agacggctgt tttactgtgg taagagaagg gcttattaga cttgatgttt gaatatcatc
    17281 aaatcccacg acacttatat catttggtat acttaatcct ctttctttaa gacctcttat
    17341 gacacctatt gcaatcaaat catttgcaca aaatattgca tcaaaatcta tcttttctaa
    17401 attttttata aattcttgtc cccattcaat cttatatttt ccttcaaata cataagcagg
    17461 attgtagctt aaattacact cgattagagc ctttttatat ccttctaatc tatctactgc
    17521 tatttcattt tgaagtggac cacttaggta tattattttc ttatttccaa tatctaataa
    17581 atgttttgta gctatatagg ccccttcaaa gttatttatt ttaacaattc cttttaaggt
    17641 ttctttgttc atacttatct tcttatcaat caagacagtt ggtattttta tatctttata
    17701 atttgcttct ttccagtttg tatttgaaga tgctgcaaat ataattccat ctatcatcct
    17761 ctctgatagt gttcttattc cttcatattc ttttttagca tcttcatctg tattacataa
    17821 aattatattg taaccttctt cattagcttt gtcttctaca cctcttgata catctgtaaa
    17881 gaatggattt cgtatatctg gtataagaag ccctatagta ttagtttttt tagttactaa
    17941 actttgtgct aatttatttg gtacataatt tttttccttc attattttca aaattttttc
    18001 tcttgttgcc tgacttatat tttcatcttt attattaatg acttttgaca cagttgtttt
    18061 agaaacacca gccaattcgc caatttcttt tatagttata ctcaagaagt tcacccccaa
    18121 aatttaggaa accgttttac ttaaccggtt acctagatac tatcacatct tttttccatt
    18181 tgcaaccatt ttatataaat tttgatattt ttcccttttt tcaaaatatt gcaacttata
    18241 attcaatttt aatatttaaa ttaatctgca aaaaaaaatt aatatacttt tataattatc
    18301 taaaagtata ttaattaatt taagcagtat ttattaaagt tcaaatcctt gctctataat
    18361 cattttttta tcattttcaa tcccacttcc aacagttgtc aaataatcac caacaattgc
    18421 agaatttact cccccattaa atccaacttt gtcatatccc tttaatgata gccttccacc
    18481 agcatacctt atgtacacat taggaattat aaacctaaat actgctgttg tttttagtat
    18541 ttccattggt tctaatacat cataattttc cattggtgta ttcttaatag gatttaaaat
    18601 gtttattgga aatgatttta catttaattc tcgtatttca aaagccattt ttagtctctg
    18661 ttcttcactc tcattcattc caattatacc acctacacat acatctagcc cagctttttt
    18721 agcatctttt atagttttta tcctatcttt atatgtgtgt gttgtacata tattatgaaa
    18781 attatctcta cacgtctcaa cattgtggtg atatgtagtc acacctgctg acttcaacat
    18841 tttagcttgc tcataatcta taatacctaa agatgcacat aattttaaat tagtattttc
    18901 cctcaatcct tcatagatat ttaaaatatt attaaactcc tttcctgaca tacctttacc
    18961 acttgtaacc aatgagaatc tatgcactcc tttactctcc atctctttag ctctatttaa
    19021 gatttcattg taatctaata atgaatattc ttctacacca gttttataat gagatgattg
    19081 agcacaaaat ttacagtctt cactacattt gccagattta gcattcatta tcgtacataa
    19141 atctgctttt cttcccataa aatattctct tatttcattt gcagatttta atagaatatc
    19201 aaaatcgttt ttattatttg tatcaaggct tattaaatta agagcttctt cataacttat
    19261 ttctttttct ctcaatactt tattttttaa ttttattatg tatttttcca tatatcctcc
    19321 tatttgtcaa cttaatattt ttatgtagtt tacttattat atatagtatt gcatatataa
    19381 catttattgg tcaactttat tttagacaca agtttactat acacaaaaaa atactgcttc
    19441 aaaataatat tagtaaatgg attatacata ttattattaa aacagtattt tttattagaa
    19501 tataattctt actggtttat aaaactatcc ttgtcttaac tccatccaag ctttccattg
    19561 taataacctc taagccttca tattctctaa atagccattt taaatccttc atggcttgat
    19621 taacctgact ttttgttaga ttatttataa aatattcttt tctagtttcc tcatactctt
    19681 tgctagtcaa aaagtttctt agaaaattaa acgcaaatac acttggaata ttgtttacat
    19741 tagccttctt gctgttttcc ttctcatagt aaattttcat aaatgcatac tcctttgata
    19801 cttttagatt tctcttacaa taattatatg catttaagtg ctactattct tataatttta
    19861 ttaattcata ttctttactt cccataccca tttcacatgc atagtctatt attctagttc
    19921 catttacatg aggatgttca tgtttgaaaa catcatgacc catttcctta caaatcaaat
    19981 catagcatgc ttgttcaata gctacagggt ctgttgatgc taatattcct atatcatggg
    20041 caattggtct acctgaccaa ggtacacaat cacaaagtgg agttacattc ataacaaaag
    20101 ttatataccc taccttgtct tttttatttg atactgctcc ataagcgtat tctgccatct
    20161 tttcgacaaa cacatctgag tcactttccc attgtatagt tactgctcta gttggacaga
    20221 cagttggaca ttctccacat ccataacata catcagaatc tataactgct tttttatcca
    20281 ctatacttat agcttttgta ggacaagaat taacacactt tccacaacct acacacttct
    20341 tttcctttac tactggagta acatcagaat gttgcatttg ttttcctgct gcacttgcac
    20401 atcccatagc taagtttttt aatgctcctc caaaacctgc tgcttcatga cctttaaaat
    20461 gactcattac tatcattgca gaagaattat aaatttctcc acctattttt acactttcaa
    20521 aatgtttttt gtctattttt acattctcat aatttctact atataatcca tctgcaatta
    20581 ttactggtgc atttacaact gcataagcaa atccattttc tatagcagtt gtaagatggt
    20641 ctacagaatt tgttctactc cctgtataca gtgtatttgt atctgttaaa aatggctttc
    20701 cttcgcagtc tttaacctta tcaaccactt gtctaactgc cacaggactc atatatgtag
    20761 tatttccctt ttctccaaag tgaagtttaa ttgcaacttg gtcattcttt tctattaaat
    20821 ctttgaatcc tgcttcatca aataatcttc ttacattgtt tggtacgttt ttattttgcg
    20881 aatttgagta taaatcacaa aaatatactt ttgacttttc catatctaca cccctttaaa
    20941 atatttactt atactaattt tatcactttt aaagtaattt ttagtatatt ttaacataat
    21001 taaatattct tatatttatt tgatacaaat aatattattt gtattatttt ctacacttaa
    21061 ttctatatat taaaaatcaa aaagacttga aacttaagtc caagtctttt tgatttttag
    21121 gtgtagtttt taacaacata agattacttt accttgtgat aaaggtatta ttaaactggt
    21181 tttttattaa ataaaataac agctgctagt aaacatacta cagaaataag aactgttata
    21241 ataattggaa taataaattc tggcattgcc actttccctg aaatcaagtc tatatttttt
    21301 gacatcaaga aattaggagt ataaggtgca atctgtttag gaatagaaat taaactcaat
    21361 aaaagagttg ccaccaatac aagtaaaaca ctggcaaatg ctggtctaaa tagtacacac
    21421 ccaagaatta atacactaat atacataatt cctataagcc ataaattaaa tgctgaaaat
    21481 ataatatgat taagatttgc agttggccaa aaatatattg tatagccata agcaaataaa
    21541 aaactcaacc aaaaaccaat tgtcataata atcaccgtaa cagagaattt agacaatact
    21601 atagatgaac gtgataaacc tttagtcagc ataataacaa gtgtcccttt agaatattca
    21661 tttgataaaa tattacaaaa aataattaga gttaaactca taccaagacc agagatattg
    21721 ctaaaaaatt gtgtccaaga atctaaagca gttggtgcag cagtaacttt taaagtcggt
    21781 gcaaaatgag caatcaagtc tggcataaat tttgcagaaa taggactact tataccaaat
    21841 attagaaata aaataattaa actaaataat ttataatttc ttaaattctc tttaaattct
    21901 ttttttgtaa atgctatgta ttctctcact ttactacctc caaaaataaa ttttcaagtg
    21961 ataattctat tagttccatc tttactggac aaagattcat ttctgcgagt gtagatataa
    22021 ctgttttttg tattgctttt atatctttac catgcaaaac aatttccata ttagtttctt
    22081 ctgaatcttt tagtaaggat ttaataccat cactagactt aaacttttga atttcatcat
    22141 tacttgcaaa ctccagtaaa agtctatcct ttccgtgcat actttttatt tctgaaagtg
    22201 taccactaag ggcaatgctt cctttgttta atatagcaac atggtcacag attctttcaa
    22261 catctgatag tatatgtgtt gaaaatatta cagttgttga gtctttgatt ttaagcataa
    22321 tatctaatat ttcttttcga ccaacagggt caagtgcact tgttggttca tcacaaataa
    22381 gtaatttggg gcgtgaaagc aaagcttgag ctataccaag tcgttgcttc attccacgag
    22441 aaaacccacc tattcgtctc ttttcatttc caagacccac aagtgataac aactcttcac
    22501 tccttatctg tatttctttt tttgaaagtc ccgtaatttc accacaaaga gaaagatatt
    22561 caagtggtct catatagttg taaaactctg gaacatcagg cagataacct acatgacgat
    22621 tagaacttgt tttcccatag gtcactttct caccacaaac atctatagtt ccactatctg
    22681 gtttaagtaa cccaagtacc attttcattg ttgtagtctt acctgcacca ttcttaccta
    22741 caaacccaaa gactgaccct tctggtacag taaaatttaa attatctatt atctttcgat
    22801 taccaaaacc ttttgataat ccatttattg agacaatatt catcattctt cacctcttcc
    22861 tattgtaaaa tacaaaattg gtcctattag actaataaac agtactacaa taatccatat
    22921 tgccttattt ccaattttat aatttggatg tctcaataca tgaacaagtg cagtaattat
    22981 aagtattaaa tctaaaataa taacaggaac caaaagtggt aagtattcca tcaaattttc
    23041 cataatctta ttcctccaat aaagataatt tttctataag aaatttgtat tctttgtttt
    23101 cacttaatac agaaaacatt ggattatttt taatagcagc aacaatacct gcttttacga
    23161 ttgtatcatc acgtgtaata cctgttccaa tttcagaaat ccatctgtca agtttattaa
    23221 aaaagtcatc cccatgtatt ataattgggt atatatcacg tgttgctaaa tctacatatt
    23281 ttcgtaatga tttaatagct ccttcattat caccatgtat taaattaatt tgtgcctgtg
    23341 ttaaatatga agaaagcata atagcaggag ataatgtatc aagctcaaat atatctgaaa
    23401 ttgctagaat acgtctttct atttccttca tttgtaattt atctgcattt tgcaaaatac
    23461 ccactaggtt ttggactaat gatataaggt tctgatatgc accaagttga aatgtttctc
    23521 tcgcttcatc catttgacca ttcatcattt gcccctgtgc aagaagtata gattcattta
    23581 tcatgggaaa attgctgttt tgcaataaat caatcacttg tatgggttga tttaacaata
    23641 tataacaagt tgcctccata ctttttgctt gacggcaaat atctatgtca ttacaagttt
    23701 cctgtatacg aataaatatt tctaatgctt cactaattaa tagttcacgc tttttttcat
    23761 ctacaatatc atagtgatta actattaaaa gacccatccg aaaaatcaaa ggaaaacatg
    23821 aataatattt ttttatgatt tctcttattt catccatgac ttcatcaaat ggtttaaccg
    23881 taaagtcttt gcacagttta ttatacagtt tattaatatc ttccttcatc atttgaggtt
    23941 cataacatat taactcatca acggtaatgt tgaaatatgt cgcgagttgc ggtaaaaaag
    24001 ttatgtcagg atagctttgt ccagtttccc atttagatac agaagcttta gaaacgccta
    24061 tataatttgc aagttcatct tgtgtaattc ctttttcttt acgctttaaa atcagcgttt
    24121 ttgcgatgtt taattcattc atgtcaatcc ctccttatgt ataattatat ccttaaacat
    24181 gtaaagctaa caagcgattt gaagttgact tttgacgaaa aaatcaacca cagagaaaca
    24241 aataaacaag tatataaaat atatatttaa atttatcttt aatctctttt gtaaaatatg
    24301 taaactttgt aaataaaatc catattatat aaaactaata gttaatctat ctaaatacag
    24361 tttttattta tcacgttttt aaatattttg tgtaaaacct cttttaatat aaacacctta
    24421 ttttcatttc tcatttcata ttctttttaa aatactgaat ataactcttc gattttccat
    24481 ttaattcttt tataaagtta ttattcgtat ttatttctct aattataaca ggcaactatc
    24541 atgtattggt atttgtctat tatataaaaa tctataaaag aaaagcagtc aatcatttag
    24601 attaactgct tgtacatata tcttattaaa ctgtataaac tataattttt attattctcc
    24661 attttcatcc caagtcataa atccccatcc actatctgga taagtatcaa tagacttttc
    24721 tctaatcata taaccaactt tataacactc ttttgttatt ttattagata gtatacatcc
    24781 ttctccattt atctaattcc attcaattaa cttttctttt caaccttaac ttttataaaa
    24841 tcatcttttt taataatttc atacttattt tctcttcaac atcatcaaat gagggtgtct
    24901 caaaattaac tttttacttc ataaggcact cttttttgta tgaagtaaaa tatattttca
    24961 tcatttcaac aataagtaag aggcttatct ctattttgag acagccccat ttgatggtgt
    25021 tgaacattta aataaggttg aactcgtttt atctctcttt ttaagatatc tgtaaatttg
    25081 cacataaagt ctcttcttct tttacaattc taatagtttt attaaagcca aagtatatat
    25141 ctccatattc tttcgtatat gatttattgg tactctttca tctactccat gaccaccagt
    25201 tttatacgct aagaacttag gtccaaacgc caccatatct ttaaaccaac ttgcatatgt
    25261 gccaccaccc atagcaattg tatatccatt ttcatctgtt acttcttcat aggcttctaa
    25321 taatttttta agtactaaat tactctcatc cacataatgt aagtctttat gagcaataac
    25381 ctctattttc caaccattac aaaaaacctt tttgaatcta tctattatat tgtttaaaac
    25441 tatattttta ccatacctta tatctaactc acatacgatt ttttcctcat ttacttttaa
    25501 tattcctaaa tttaaggtag tgtttttgaa tacctcatca tattgattaa tccctaatgc
    25561 atctccataa taatcactac aaaggtattt tgaaactaat tcgatatctt ctctatgctg
    25621 aaaatccata ttatcctcaa ctatctttat taccatttta gatatagcat tttctccctt
    25681 ttcaggatta cttgcatgta cagctactcc tttagtagtt aactctgaaa taattccatt
    25741 aataattttt gcagtacaat gagatggaac aacattttct ttagttcctc cccttactat
    25801 tatgtaaggt ttacttttgt caattttaat ttctttttct atccttatat gaacccttcc
    25861 tttttctcca ttaaccactg gatacatagc atctggagta aatcccatac ttggaatttc
    25921 ttcaccttta tctaagtaat atttgataca tttcatacct gtctcctcat ttgtaccaaa
    25981 aattaatctt attcttttat taattgtagg atacatatcc tctatgtttt tcaatacatg
    26041 tataagcata gatacagcac ccttattatc tattacacct cttccataaa taatattgtc
    26101 aattactgct cccgaaaatg ggtctacact ccacccctct cctggtggaa ctatatctaa
    26161 atgcattgga atccctatta attcctctcc ctctccaatt tctgcatatc caatataatt
    26221 atcaatattt ttaacactaa aacctaaact agcacagtaa tctaaagttt tatctaaaga
    26281 ttttttaggt cctataccaa aaggacattg tgaaataggt tcaccttgtt gtgaatcaat
    26341 ttttatcaat tcttttagaa attctatggt tctatttaaa ctattatcta cacttctgct
    26401 tatatccata aatcaaccta ctttctatct ttttaaagcc tgtccttaaa gaacaggctt
    26461 ttagcattaa aaattatttt tttgtaaata ctaattcaca aacttcatca tcatgagcac
    26521 atttttgagc aaaatctaat ttaacacctt gtgcgcagtc aactcttcca taatccccat
    26581 aacaagctaa tctacaaatt tcttttcttt cttctttagt taatccatat tctttccaag
    26641 cagcatctaa tggacagtga tggaatttta aaacgccatt ctcatctgta ttttctacta
    26701 attccatttc aaacactttt tgtcctttac tgttatataa catttctgcc atttttcctg
    26761 gagtatctgc tacgttatat ttttgacctc tcattttacc aaatccatat attgcttctt
    26821 tacatatatc atctggatta gctcctaatt tttcagcttc tttcataaga agatagaacc
    26881 atactgctct ttctcctgtt gctcctctaa ttccttctaa atattccttt tctgtataca
    26941 ttttttctga catttctttc tcctcctaaa attaaattct atattttaat cactgtgaat
    27001 tagaatattc caatgaatga ccctaccaat gctaatacaa ctaaaattac taataactta
    27061 gttattgtcc acttcttgta tttcattccc caatatacga agaatacaac accaagtggt
    27121 aataaacctg gagcaatcat atttaatgta tcttgaacaa caattgcttt accaccaata
    27181 tcaaatgata gcggagttga aagcttaact gtagttgcag ataatgctcc catcataaac
    27241 attcctagaa ttgaagcacc atcaattatc ttattgacaa taccacctga tagaattttc
    27301 ttaattgaat ctctacctaa agaatatcct aaatgaaata agtaataacc ttcgcaaaat
    27361 agtaatatac taaacattat tgggaaaaat gcacctataa cacttccttc tgctccaaat
    27421 gaagcaccta aagctaagaa tattgtttga aatgtaccaa aatctaaagt atctccaatt
    27481 ccagccaaag gtcccataag accattctta acacctgaaa taacttctcc tgggattttt
    27541 ccttcagtag ctttctcttc ttccatagct aaaactgtac cgtgaattaa tcctccccat
    27601 atagcttgag tattaaaaaa ttgtaagtgt ctctttaacg catctactaa atcttctttt
    27661 ctcttatata acttttctaa agccggagtg aaacttgcac aaactgctaa tgcttgcatt
    27721 ctttcaaaag agttggataa ttctgctgtc caccaccatc ttagatatgt ttttgttaca
    27781 tctttctttg taagtactct tgtcttatta acttcagttg gaccttgtcc atttttaact
    27841 tctttatttt ttatttcttg cattatactt cacctaccct tttgtcttct ttcataaagg
    27901 taattaaaag agctatacaa acaccaaata ttgcagctgc agtaattgat atttcaaaat
    27961 attgaaccat aaaaaatcct ataataaaca ttggtaaaaa tttattttta cctatagtaa
    28021 atattgttgt tgcaaaacct aatgcaggta atataccgcc cattactgtt aatccattca
    28081 ttaaccattg tggtataaca tctaataatg attgaactaa atctgctcca aaaaagttac
    28141 atacaaaaac tattggaaac cttaaaacaa acccaaatat taaagaataa agtgttgcac
    28201 atctccagat gccttttgta ttaccttctt cagcatactt atctgcctta tgaaccaata
    28261 cagcattacc agttcttctt aagttattaa ctaatactcc tataacacct aaaggtaccg
    28321 caatagatac tgcaacttct gcattaacac cagtttgaag tgctactggt attgcaataa
    28381 gagcagctag acatttatct gatggaatat ttccccctgc tgcgaccatt cctagataaa
    28441 ccatttctat acttgcacca acaatcatac cagttgttac atcaccccaa agtaatccaa
    28501 ggctaaaacc tataaataaa ggagacttta gtgttgagaa aagggtatac cctgcaagac
    28561 ctgctgcaaa ccaataccat aatcctgtta caattgccaa catcaaaaca gattccattt
    28621 ataattcctc ctaatttata ttttttattt aaatttcttt aacgcatttt catatgtcat
    28681 agatgattcc tctggtataa cttgtaggac tatttcaacc ccattttcat taagttcatt
    28741 aagttgttct acatcctcat ttcctaatga aacagctgta aacaccattt tctttcctgc
    28801 ttcatttgga atacctccta attgaatctt ttcatattta agtccagctt tataagcctt
    28861 atttgccata tcaacatttt taaatagaat aaatatattt ttatctccta aagtgttgtt
    28921 ttggaatgct tgtcccgcat cttctgctgt taaaataact acttctactc ctgatggtgc
    28981 tgccatttta tatatgtcag ccataaattc atcttgacct aagaagtcat caactattat
    29041 tattttttga gcttgagcga tttttaccca ttttgttata acttgcccat gaattaatct
    29101 gtggtctact cttactaatg ttatttttgc cattatattc acctcataat ttatattttt
    29161 ttaaattctt taattaaatc cacacaaagg ttattatttt ttttgacgat tctttctggt
    29221 aatgtatgta atttatcttc tttgcttaat tcttcatcta cgattaaaat tgtctgtaag
    29281 ctaagtccat ttattgcatc tattcctctt cttatagcaa cagctattgc aacacttgat
    29341 gtagatcctc catataaatc tgatattata attttcacat cttctttatc tactacttct
    29401 tcaacctctt tcataaatac agaaacatct ttttcagaac ttagtgataa aacttcatat
    29461 tgatttgaca atccaaagtt tttatttgtt tcttctacta agacttttcc ccaagttcca
    29521 tggcacagta tgattacctt atatttattc attgctaaat aaactctcct ttatagcgat
    29581 taatattttg gtttaattct acttcttctt catcaggtac catttgaatt gatacattaa
    29641 tattcttttt aataaattca tctattaaaa gaaactcttt tttattaatg tatacatttt
    29701 gagatatttt cttttttcct attcctgtag gtattcttcc aacaataagt tttttgatat
    29761 taatcccttc ttctatcatt ctatttgcag tatctaaatt tttaattaat acaaaaacgt
    29821 tatcatcagc ttgattatta taaaaatatc tccttgattc acttacagtt aatattgata
    29881 aatcaatatt ctttggtgct gccattttta tcaaaccttt agcaataaca tcattggttg
    29941 tttcatcatc tactactact atctttttta cacctagatg cttaacccat ttatatataa
    30001 cttgaccatg tattaatcta tcatcacatc tgcaatattt tactaaagac atttttaatc
    30061 aaactccttt ttctattaca ttgagctaag aactttgtta atattgttta taccagtttg
    30121 tcctgcttca atacatgctt ctgctaactc ttctaaactt tttccctctc tattaattaa
    30181 agcttcaagt agcattggaa gatttactcc agtaagtgca tgaaacttgc cacctttttt
    30241 aaggtttaaa cttgcaacat tacttggcga acctcctaat aggtcagcta atactaaaac
    30301 tccgtcacct tcatctaatt catttaactt ttctacaaaa tttttattta agtcttcaat
    30361 attatcattc ctatttagtt taattgctgc tgttctttct gctggtcctg caataagttc
    30421 acagcttttt ataatttctt cactaaaact cccatgagtc ataactatta ttcctatcac
    30481 caatttcacc tcacttttct tgtcactttt tatataagca attgccgtgc caacttatgt
    30541 gtatcaataa caaatggcta ttttacagga tttaatcaaa actttttatt caattttttt
    30601 taaaaactta ttatttcgat atgtatcaaa agattttttc aacctgtatc aaatctgtat
    30661 caaaaaaagt aaaaaaaaga tagccttttg gctattttta aattttgtat caacttttga
    30721 atttatctgt atcatattgt gattcaaata tatctaatat atttgcatat tccatatctg
    30781 aaataattat atcgaatgtc tcttctacta gcttaaaact ttcttttata actaaatata
    30841 attctttatt tctactaatt ctttcttcat atgatttata aactaaagac tcttttatta
    30901 ttactctttc aatcatacat gaacaatgaa atataaactt tactaaaagt tcatcttgaa
    30961 ttactaaaga atagtgttca ctaattctat taattacttc ttttaatata aaataagcct
    31021 tttccccatt taaaaaagtc aaagttttac taatattatc aattagtaat ctatcaaaat
    31081 atctaccacc attatctttt tcagcatatg taacttccat atctccataa tgtttcttta
    31141 tagattctat aatattaaaa tataatttct ctaatgtcat ttctggagtt agagcctttc
    31201 tagttgcttc tattacaata ggtgtactta ccatatctat tgcttttact tcttttcctg
    31261 tagcatcacg aataacttta gcaaatgtta aaatagaccc catatcagtt aaaattaaaa
    31321 ttccctttcc tttatcaatt ttattggcta tttctacagc ttgtactaaa atatcctgaa
    31381 ctctatcttc taatcccata ttaattgcca ctgcatggtt acaatccagt aaagtattgg
    31441 ctacattcac catgctagat gctgtagatt caccatgcat tatgactaat attgctatac
    31501 tctcctcatt taatcccaca tacgataaat aaagaaatgt tgctaaaaaa attgcttcat
    31561 cttctggaaa ctctactcca tacattaatg acatgttaga taatatttct tttgctatgt
    31621 tatattcata tgctctttcc ttcataattt catctttatt aggatgcttt actatatttc
    31681 caatctttat tctttcaatt aaattctgaa tatgtaaagc tatagctttt attaatttat
    31741 ctaatccttc tcttttgctc catttatcat gcttttgtaa aatatatttt acagtagttg
    31801 caattgaatc attaacaatg ttgttataag ctgtttgatt actactatta tatataaaag
    31861 tattcattaa attataggaa tacttctgta tgtctccatc tataacactt ctaatttgtg
    31921 actctttaat accttcttgt tgaagtttat tccaagtttc ttttatcatt ccataaaaat
    31981 ctaaatcata ttttttattt tctattaata aattttcact ttcaaaatcc ttttcttctg
    32041 gtaaaaaaat aatatcatct tttccaataa aactgaaatt ttgtacaaac tcctcttttc
    32101 tattatttcc atataatgat tctctaatat tatttggtag aagagagagc cttacatata
    32161 cacattccct tttataggtc atataatcta aaaaagctct tgcacaaatt aattgtatat
    32221 cgctttttaa ttggcctatg tttcccttac acttatataa aataaatgcc ttaataactt
    32281 cttttgaaac ctttaactta acaccaatcc taacactctc ttctttaaaa aaataacata
    32341 taagcttcat tctctcttga aagcctcttt cctctaaaga cggaatcttt atagttacag
    32401 gtattcttct taaaaacgtt tccaacattg ctgtttctgg gtcttctgta gtggctgcaa
    32461 ttatcataac tctacactcg tgtaccttat tagcctctcc taaccttcta tatatccctt
    32521 tatccataag cagaaatagc atttcttgtc cctctgcaga taatctatga acttcatcta
    32581 aaaacaatac tccattatta gcttcatgta caataccata cttatcttta tcagctccag
    32641 taaatgctcc ttttacatat ccaaaaagct gcgctaataa taattgctga ttatcagaat
    32701 aatcagcaca gttaaatatg ataaatggtg cattatcact atcttctttt atagttaaac
    32761 tatacttata catatattct gcaaatatag atttaccaac tcctgtaggt cctattatta
    32821 atgtactcaa ccccttaggt ggatatatta ctgctgcttt agcctgttct atttgggatc
    32881 ttaaacttcc atcacatcct actaaattaa aaatattgtt ctcttttttt atactctcta
    32941 aaatatactc atctttgata gaatcatttt cactatattc gtttatagag ttaatattat
    33001 caaatatccc tttatttagt ttctttccta aaatactctc aatactttct ttatataagt
    33061 actgaacagg cttacccttt atctttataa tgatactttc ttttattaat tgatttaatt
    33121 ccttactagc attacttcta tttataccta cttcagtagc tatatattct gcatcaaatc
    33181 caaatctaat gccattatta aagttcaagt gttcttctgt taaccttttc aagcaaatta
    33241 aaactttttc tttccttgat agcttctttt gtgtcatagt taacctcccc tataagcagt
    33301 aatactgtta aacatttatt attaagctta attctacaat attttaatat ttttgtctaa
    33361 ttatgtaact attgattttc tttcctattc gttttataat ataaattacg ttaccctcat
    33421 cttttataga ggaggaattt atatgaattt tttatcagat ttacacaccc actctatagt
    33481 cagtggtcat ggctatagca ctttactaga aaatattaat tattgtaaag aaaatggaat
    33541 taagatacta ggtacatctg aacatggtcc taagatgcct ggttctcccc acagatggta
    33601 ctttcacaac attcaaaata tcccaagaat cataaataac attataattt taagaggctg
    33661 tgaagcaaat atactagata ttaaaggaaa catagaccta gagccttttg taattcctcg
    33721 gttagattat cttatcttgt catttcacga agctgtgttt tctccaaata cattagagaa
    33781 taatactaaa gctttaataa atgcaataaa taagcatgat aatattgaaa tattaggaca
    33841 ccttggaaac ccaaactacc caatcgacta tgaattaatc attaaattag ctatagaaaa
    33901 gaatatctta atagaaataa ataattgttc tattaaaggc gtgtcaagaa atggtagctc
    33961 ggataactgt aagtatattg ctacactttg caaaaaatat ggtgctaaaa tcatactaac
    34021 ttcagatgct cacatttgtt ttgacatagg taactatgag tattctgaaa atatcttaaa
    34081 ggaaattaat tttccagatg aattaataat gaattatcct aaaaaactta ttaatcattt
    34141 tcatcaaaaa ggtaaattac tagatgttga ttatacaaat atctaagtaa taatacatgc
    34201 ttactttaac tcccataaaa attttaatac tatttatatt atatgaaata aagaaattat
    34261 aataaagaag ctatttaata aagcttaatt acttttatga acttgatgga ttgatatggt
    34321 ctatgatagc aatagaaatt ataacatttt taataagctt agttttatat accttatagt
    34381 ataaagctaa aaaaaagaat catctaaaat aaagtaaatc ttatataagg tttactttat
    34441 ttttatttgt aataatcatc aatacaaatt attttattat atgtaattat ttatgtctta
    34501 accaatttta tcgaaaataa cagtcttctc ttttaaagag atttttccta cttgatatcc
    34561 atattcattt aattcctttt tatatttcaa aaacgaatgg tctatctcta tcccagcaat
    34621 atcttttatt tcttcaaaag ttaatttaaa cgattgacta ttgtttttct taacatattc
    34681 ccataaagaa ctatatttac tcatcttata tcactccttt taaaatcata tcttatctat
    34741 taatttatat tctatcatta ttaatgtata aagtcatgct acttattatt tatatataaa
    34801 aatatccaaa taataagt
//
LOCUS       DAMJWC010000042        34793 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMJWC010000042 DAMJWC010000000
VERSION     DAMJWC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.042"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(98..754)
                     /locus_tag="PC503_002316"
     CDS             complement(98..754)
                     /locus_tag="PC503_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2528288.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(809..1438)
                     /locus_tag="PC503_002317"
     CDS             complement(809..1438)
                     /locus_tag="PC503_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2528289.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1569..2210)
                     /locus_tag="PC503_002318"
     CDS             complement(1569..2210)
                     /locus_tag="PC503_002318"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF2528290.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2219..2890)
                     /locus_tag="PC503_002319"
     CDS             complement(2219..2890)
                     /locus_tag="PC503_002319"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2528291.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2895..3779)
                     /gene="rsgA"
                     /locus_tag="PC503_002320"
     CDS             complement(2895..3779)
                     /gene="rsgA"
                     /locus_tag="PC503_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2528292.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3877..4614)
                     /locus_tag="PC503_002321"
     CDS             complement(3877..4614)
                     /locus_tag="PC503_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2528293.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4722..6737)
                     /gene="pknB"
                     /locus_tag="PC503_002322"
     CDS             complement(4722..6737)
                     /gene="pknB"
                     /locus_tag="PC503_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF2528294.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6754..7506)
                     /locus_tag="PC503_002323"
     CDS             complement(6754..7506)
                     /locus_tag="PC503_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF2528295.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7526..8557)
                     /gene="rlmN"
                     /locus_tag="PC503_002324"
     CDS             complement(7526..8557)
                     /gene="rlmN"
                     /locus_tag="PC503_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2528296.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8565..9890)
                     /gene="rsmB"
                     /locus_tag="PC503_002325"
     CDS             complement(8565..9890)
                     /gene="rsmB"
                     /locus_tag="PC503_002325"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF2528297.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9952..10653)
                     /locus_tag="PC503_002326"
     CDS             complement(9952..10653)
                     /locus_tag="PC503_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF2528298.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10722..11474)
                     /locus_tag="PC503_002327"
     CDS             complement(10722..11474)
                     /locus_tag="PC503_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF2528299.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDIMDIEKAIGFLTGKNILVCN"
     gene            complement(11484..12413)
                     /locus_tag="PC503_002328"
     CDS             complement(11484..12413)
                     /locus_tag="PC503_002328"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF2528300.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12428..12868)
                     /gene="def"
                     /locus_tag="PC503_002329"
     CDS             complement(12428..12868)
                     /gene="def"
                     /locus_tag="PC503_002329"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2528301.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12886..15411)
                     /gene="priA"
                     /locus_tag="PC503_002330"
     CDS             complement(12886..15411)
                     /gene="priA"
                     /locus_tag="PC503_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF2528302.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15650..16849)
                     /gene="coaBC"
                     /locus_tag="PC503_002331"
     CDS             complement(15650..16849)
                     /gene="coaBC"
                     /locus_tag="PC503_002331"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF2528303.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16854..17120)
                     /locus_tag="PC503_002332"
     CDS             complement(16854..17120)
                     /locus_tag="PC503_002332"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF2528304.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17123..17740)
                     /gene="gmk"
                     /locus_tag="PC503_002333"
     CDS             complement(17123..17740)
                     /gene="gmk"
                     /locus_tag="PC503_002333"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF2528305.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17770..18651)
                     /locus_tag="PC503_002334"
     CDS             complement(17770..18651)
                     /locus_tag="PC503_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF2528306.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18655..19485)
                     /locus_tag="PC503_002335"
     CDS             complement(18655..19485)
                     /locus_tag="PC503_002335"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF2528307.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19772..20806)
                     /gene="ltaE"
                     /locus_tag="PC503_002336"
     CDS             complement(19772..20806)
                     /gene="ltaE"
                     /locus_tag="PC503_002336"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF2528308.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21102..22877
                     /locus_tag="PC503_002337"
     CDS             21102..22877
                     /locus_tag="PC503_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF2528309.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23092..24744)
                     /gene="abc-f"
                     /locus_tag="PC503_002338"
     CDS             complement(23092..24744)
                     /gene="abc-f"
                     /locus_tag="PC503_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HDF2528310.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(25043..26254)
                     /locus_tag="PC503_002339"
     CDS             complement(25043..26254)
                     /locus_tag="PC503_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF2528311.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26538..27071)
                     /gene="pyrR"
                     /locus_tag="PC503_002340"
     CDS             complement(26538..27071)
                     /gene="pyrR"
                     /locus_tag="PC503_002340"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF2528312.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27431..28378)
                     /locus_tag="PC503_002341"
     CDS             complement(27431..28378)
                     /locus_tag="PC503_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2528313.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28347..28793)
                     /gene="lspA"
                     /locus_tag="PC503_002342"
     CDS             complement(28347..28793)
                     /gene="lspA"
                     /locus_tag="PC503_002342"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2528314.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLVDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29103..29882)
                     /locus_tag="PC503_002343"
     CDS             complement(29103..29882)
                     /locus_tag="PC503_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2528315.1"
                     /translation="MKKIICGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29937..30419)
                     /locus_tag="PC503_002344"
     CDS             complement(29937..30419)
                     /locus_tag="PC503_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2528316.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30685..32106)
                     /locus_tag="PC503_002345"
     CDS             complement(30685..32106)
                     /locus_tag="PC503_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2528317.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32252..33022)
                     /locus_tag="PC503_002346"
                     /pseudo
     CDS             complement(32252..33022)
                     /locus_tag="PC503_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(33027..34229)
                     /locus_tag="PC503_002347"
     CDS             complement(33027..34229)
                     /locus_tag="PC503_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2528318.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        11078 a         6388 c         3486 g        13841 t
ORIGIN      
        1 aattaatatc aataaaacct actttttaat tttttaaata tttattttta atttattttg
       61 tttttaattt acttcgattt taaaatgtcc ttgactttta ttttataaat gtacatattt
      121 cttctactgg ttttttagat ggactcttca aattgtcctc tggcactcca agagctaaca
      181 ttgcacctaa aaaatactct cccttttcaa aaccagtttc tgcttctaaa acagcttcta
      241 tctcatctgc tgcatagttt tgacttgtca accaacaaga accatatcca agttcaattg
      301 ctgatagtgt aaagttttca attgcagcac ctagactctg catacctgga tttcttataa
      361 ataatttatc tatagtctcc ttaggtgcat ctataagctc taattcataa tatcctgatg
      421 gattatatac ctttgtaaaa actaatacta aaactggagc ttttaagtaa aatagtgtaa
      481 aatttttaac aaattttcta aatctattag ccttatccac tgatacttta tccatttcta
      541 caagtatttc ttgttgcttt ttagttatca catctgctat cttttccatt aaatcacggc
      601 gttttataac aacaaaatgc cagttttgaa tattcttgcc tgatggtgct gcacctgctg
      661 cttttatcat ttttaaaata tcttcatctg atacatcttg atttttaaac tttcttacac
      721 tttgtctttt aaaaatagta tcttgtaatt ccatttttaa atccccccat aactttttta
      781 ttattttaat ataattttta aactcatctt attttaatat atcatgttct aacaaatctt
      841 taaatgaatc tataaaataa tcatatacat ctacattccc aaacccatat ttggcatata
      901 taaaaggtat acctacaaac ttagcactat ttgcatcacc ttgcgtatca ccaacataga
      961 ttggatttat taatttattt ctttcaatta taagtttatt attttctcct ttatgcaaac
     1021 cagtattacc aggacattca aaatctataa aatactgttc tagtttatgt gcttttaaaa
     1081 aagattctat atatccagct tgacaattac ttactataaa taatttatat tttttagata
     1141 gtaatttaag agtatcttct atatcatcaa ataatttagc tccattttca gataaatagt
     1201 cacattcttt caaagaacat tcattcaata aattcattct ttcttcttca cttaaatttg
     1261 gaaataaacg atttgctatt tcctcaaaag aaagccccat aagacttcta aataaatctt
     1321 ttgtgacact taattctatt tccttatgct cacttaaaac atcctgccag actttgcata
     1381 cttcttcagt tgaatcccac aatgttccat ctaaatcaaa aataatacta tctaccacaa
     1441 aaaatccccc ttatgtcaaa gtttattata tatttataat tatatactaa aaagcagata
     1501 caatcataaa tatattttac ttgattgtat ctgctctaca atataaaacc aattgtcaaa
     1561 atcaaatttt ataaatttct aactacaagt acacagcctt gctctacttt aatcttacaa
     1621 gaattactca acataacatt tgatattcca ataggtacag agtatttcat ataataatta
     1681 tcgagagggt attctaagcc agtaagtgtt acacccttag catcaccatt tatagctatt
     1741 acagaaatag tgtcccctgg gtttccatac aatgaaattt cctcattttc aactatatac
     1801 atctcttctt tatcagaaag tatcctagaa tatataccat cttcttttaa ataatataat
     1861 agctttatat ttgcaagagt gtggtcaatc cttcccccta aagcaccaaa aaaatcaata
     1921 tgatttgctt taagtgtctt agctaaaaaa agacaaagct ctgtatcagt ctcatctttt
     1981 ttagatggaa atttttcaaa tttaacacct ttatttttat agaagtttat cttttcttct
     2041 tctactgaat ctaaatctcc taatatataa tctggcatta tttccatttt ataagtgtga
     2101 tttgcccctc catctgcaca tattatgcag tcataacatt ccttaattat aatatctctt
     2161 gtaacttcgt aatcttcaat ttcgccattt aaaacaatac agattttcat tattaaattt
     2221 aaactaattc ttcaagagaa gcattctttc taaataaatt aactgtttct tgaatgtcat
     2281 cacttccaaa tattgcagaa cctgctacta ttacattagc tcctgcttgt acaacttcgg
     2341 ctacgttttt agggcttata ccaccatcaa cttctatatc aatgtttaat ccttgactat
     2401 ctataatagc ttttaactct ttaatcttat ctaaaacaca aggaataaat gattgtcctc
     2461 caaatccagg gttaacagac attaataata ccatatctaa atcaggtagt acatgtttaa
     2521 tcgtatctac tggtgtagct ggattaagta ctacaccagc ttttattcca tgtgatttta
     2581 tattttgtat agttctatgt agatgaacac aagcctcctg gtgaacagtt attatatcac
     2641 atcctgcttt tacaaattct tcaatatact ggtctggatt ttctatcata agatgagcat
     2701 caaataccat atttatattt tctttcttta aacttttgac tacaagtggt cctaatgtaa
     2761 tgtttggtac aaagtgtcca tccattacat cgatatgaag atattcacat cctgcacttt
     2821 ctacttttct tacatcttct aataattttg caaaatctgc tgataatatt gatggtgcta
     2881 atttaatcat gtttctaata cctcctacta ttattttgtc ttatttcatg tagcagctgt
     2941 atataactat catatctttc tttagatatt tctccatttg taacagcttc ttttatagca
     3001 caattaggtt cattttcatg aatacacttt gaaccaaact tacaatcatt aaatttatca
     3061 aattctataa aataatcttt aagttcaact tcctctatat cttcaagggc aagggaacta
     3121 aaacctggtg tatctgcaac cattccacca aattctaatt ttaaaagttc agcgtgacga
     3181 gtagtatgtt ttcccctttt tattttatca cttacaactc ctgtttgaag tttaaaattt
     3241 tcatctattt catttaataa gcttgatttt ccaactccag atggtcctgc aaacactact
     3301 acattttctt ttaattcttc ttttacttta tctatattta acttagtaat attgcttaca
     3361 ggaatgactt tatagccact aagttcatat atatttttaa cagtttctaa tgtatcatta
     3421 tcatctaaat ctgcttttgt aaggattatt acagtttcta aattttcttt ttctgccaaa
     3481 actataaatc tatctaaaag agataagttt ggtttaggat tttttattgc gaatactatt
     3541 aatgctttat ctacatttgc aataggaggt cttataagtt ctgtatctct actgtcgatt
     3601 tcttctaaga tacccttttt ttcattttca tcaacaatgc ttattttgac tctatcacca
     3661 accaaaggtg ttattttctg ctttctaaat atccctctag ccttacattc ataaatacca
     3721 ttataagtat ctacataata aaatccacta atccccttta taatttttcc ttctagcatc
     3781 aaatgcctcc ctttataaaa tttatataaa cacatactgt ttatgagtag tatatcgtgt
     3841 tattctttcc tatttttata taataccaca ttttttttaa ataacaaatc ctccgtttgg
     3901 actaattacc tgaccagtga taaaatttga tttgtctgat gccaagaaaa tagcacaatt
     3961 tgctatatct tctggagttc ctagcctcat tagaggggtt tcttccacaa gagcgtctat
     4021 atcttcctca ttatatccag ataacatgtc agtattaatg acacctggag ctatgctatt
     4081 tactctaata tttgatggtc ctacttcttt agctaatgcc tttgtcatac ctattatgcc
     4141 tgcttttgtt atagaataat gcacttcaca agacgcacct gatatacccc agattgaaga
     4201 tatattaatt atatttcctt ttttttctga tatcatgtat tttaaagcaa cttgtgaaca
     4261 ataaaagctt ccttttaaat taatattcat catattatcc caatcttcat cagttatatc
     4321 tgtaaacaac ttatcttgac ttacaccagc attgtttaca agtacatcca atcctccaaa
     4381 ttcttttata caataatcta ccatatcctc tacatcttct ctatttgaaa tatcagcctt
     4441 aaaaagtttt acagaaaaat ttttttcatt taatatagtg tacaactctt tagcttcatt
     4501 ttctgactta ttaaaattta ctaatacatt gtaaccttct tttgcaaaag ctttagacat
     4561 agctttacca atccctctag ctcctcctgt aattaaaact gttttcttct tcataaatac
     4621 ttttctcctt atattataac caattcagta ttttatacaa aacaaactgc cctttaaaga
     4681 aaatattttc tataaaagga cagctcttat tttattaata tttattctgt tttaccaatg
     4741 tttgcgccag ttcctgatga agttcctcca ttatctcctg agtttgagcc tcctgaacta
     4801 tctccattgt ctcctgagtt tgaacctcct gaacttcctc cattgtctcc tgagtttgag
     4861 cctcctgaac ttcctccatt atctcctgag tttgagcctc ctgagtttcc accactattt
     4921 cctgagtttg aacctcctga gttacttcca ttattgcctg agtttccacc actatttcct
     4981 gaatttgagc ctcctgaatt tccaccactg tttcctgagt ttgaaccagg ttctgttggt
     5041 gtattattct ctggtgttgt tggtttttta tctggtactg ttggagtctg tgtatttgat
     5101 ttttctgaac ctttgcttac atataggttt acctcatcac cttcctgagc tcttgatgag
     5161 ccagcacccg gactctgact taaaactgta ccttctttat atattgagct gtattcatac
     5221 ttaacagttc ccacttttaa gttattttct tcaataagtt gttttgcatt actcaaagta
     5281 agtcccacta cattaggaac agatgcctga cttgaacctt tacttacgac aacatttata
     5341 gtatcaccct ttttgacatt tgtacttcca ccttcaggtg tctgtgatat tatacaattt
     5401 tcatcaactt cactattata ctcttcactt tttacactca ggtataatcc ttctttttca
     5461 acagcacttt gagcttcttc taatgtcata tttacaagat taggaacagt caaagattta
     5521 ttgccaaacc ctccagcaaa taaaaactta tatgctaaga atacttgagc acacaatatc
     5581 agtatcaaaa cagccgcaat tacttttaat cttcttctag attttgggct ttcctgtttt
     5641 ttcttctttt tcttagttct cttacttgga gtactcttag gtctctgatt ctttttagct
     5701 ctcattatct cttcctcttc ttcatcttca tcatcatctt cttcataaaa atcatcatag
     5761 taatcttcat catcatccaa atcagctact tcaacaggct taaccacttt ttcaggagct
     5821 ggttttgcaa gtgttggatt tacaacttta ttaatttctt tttcatcaat tttcttagtt
     5881 gcaaaatcat catattcttt tataaaatct aaatcaatat ttttttctat atactctata
     5941 tcttctatca attcttcagc agtttgatat ctatctgcac tagatttttc tgtaagcttt
     6001 tttattgtag ttcttacact ttgaggaatc ctaacttttt cttctgatgt aaagtctata
     6061 tcatcattaa tgtgttgaag tgctatagaa attggactat ctcccctaaa tggaactttt
     6121 cctatcaaca tttcatataa aactatacct agagaataca ggtcagcatt attagttaca
     6181 aatttacctt tagcttgctc tggtgaaaaa taatgcactg aacctattat actaccaata
     6241 ttagtcattg ttgaatttga aacagctttg gctataccaa aatcagccac ttttactact
     6301 cttccttcat ttgatatgag aatattatga ggttttatat ctctatgtat aatccccttt
     6361 ttgtgcgctg cactaagtgc catagctatt tgttttgtta tatctaatgc agtatattca
     6421 tctaatatac cttcatcttg tataatctct tttagattct tcccatctac aaactccatt
     6481 acaatgtagt gaacttttcc atcttcacca acatcataaa catttactat atttggatgt
     6541 gaaagacttg ctactgcttc tgcctctctt ttaaactttg ttagaaattc atcatcatct
     6601 acaaattcag gtctaagtac tttaagtgca acagtcctgt ttaataatct gtctttagcc
     6661 tcatatacaa aggccattcc tccatcacca atcttcctga tgatttcata tcgatttcct
     6721 aaaattgtat ctcccacaat atcaccgtcc taattatact tttatcacta taaccgaaac
     6781 attatcttta ccagaaacat cattggccat acttatcaat tcttcactta tattactagt
     6841 tctctcatat tcataatcta atattaaatc tcttatatct tcatcatcaa taaacccagt
     6901 taatccatct gtcgcaagaa gtattatatc actttttttg atttctttct taaaaatatc
     6961 tacaacaacc atatcatctg ttccaattgc tctagttatt ctattcctct gtggatgtct
     7021 tcttgcctct tcttctgtaa tgacatgggc catcataagt tcttcaacca cggaatggtc
     7081 tatagttatt ttatcaaatt tttcatctgt taacaaataa catctgctat ctccaacatt
     7141 tgccacatat aagacattat tatacactat agccgtaact aatgtagttc ccattccttc
     7201 aaattctata tcttccatag attttttgtg cacaattgag tttacattat tataagcctg
     7261 ttttaatata tcatctatat agtctatttt tacattatca tgttgtaata agttttcttt
     7321 tagaaaatca attatatttt ctactgctaa tttactggcg acttcacctt ttttatgtcc
     7381 acccattcca tcagctatgg caaatattcc tattggacca tgttctgtat ctataacttc
     7441 tccctcacaa tagtcttcat tgttttttct tatttttcct atatgggagg cacaactata
     7501 aaccatacga cttcctcctt acaaattact tgtattttct tctcaattgc ccacaagctc
     7561 cactaatatc agaacccata gacatcctaa ctgtggcagg tatattgttc ttctccaaac
     7621 tatccctaaa tttataaata aatgctttat ctggtttttc gtattctctt tcttcaactt
     7681 tatttattgg aattaaattt acatgacata gcataccttt taggagctta gctaatgcct
     7741 ttgcttcttt ttctgagtca tttactcctt ttataagaga atattcaaat gtaacccttc
     7801 tatttgtctt ttttatataa tatctacatg cattcaatat ttcttcaata gaataagcat
     7861 ttgctacagg cataattttt cttcgttctt catcatatgg tgaatgaagt gataaagcta
     7921 aatttatagc tatttctaag tctgccaact catacatttt aggtactatt ccacaagttg
     7981 aaagagttat atgtctatac cctatattaa gaccattttt ttcgttaatt atttttaaaa
     8041 attgttttgt attttcaaag ttatcaagtg gctcaccact ccccatcaat acaagatttg
     8101 ataccctctt accagtatct tcttgaattt taataacttg gtctaaaatt tcccatggct
     8161 ctaagtttct aattaatcca tccattgtag atgcacaaaa attacatccc atcctacaac
     8221 ctacttggtt agaaacacag acagtaactc tactatcata atccatcatc acagtttcta
     8281 ttatatttcc atcatctaat aaaaacaaat atttttttgt attatctacc ttagattcta
     8341 actttaattc tatatctata tgccctatac atgaaacctc ttctaattta tttctcaaac
     8401 tttttggtat attgttcata tcatcaaaag tttttgcacc cttatatatc caagagaata
     8461 tttgacttcc tctaaagggc ttttcatcta tagttttcat aaactcttta agttcatctt
     8521 cagtaaaatt ttttaatact atctttttct tttccattct ctcactacct tattctcttt
     8581 aattttgcta tgaaaaaacc atctatacca tgaatattag gatatatctt taaatatcct
     8641 ttatcttgat tgtctaagtc tacatttact gtatcaattg gaacaaattc aaagttgtga
     8701 ttttcttcaa caaaagaagt aactatattt atattctcca catcttgaat tgtacatgta
     8761 ctatatacta aagttccacc aactttgaca tatttagatg cattttctaa aattttcttt
     8821 tgtatagaag tgatgtcttt taactcttct tctttcttat acttaatttc tggtttacgt
     8881 cttattatac caaaaccaga gcaaggaaca tctgctaaaa cataatcaaa tttacttata
     8941 ctattttcat caatctcaga agcatcaaat ctttctacaa acacattttt aagccccaat
     9001 ctatttacag tagagtttat aagctttagt ttatgctcaa aaatatctct agctactact
     9061 tgaccagtat tgttcattaa agtagctaag tgagtagatt tccctccagg agcactacat
     9121 acatccaaaa caaatgaacc ttcttttgga ttaattactt tccctactat catagaactt
     9181 atatcttgaa ttgtaaataa accagcctta aataattcat ttttttctat atttttcatt
     9241 ttttcgactt taatagcttc ttctaccata ggaactttta aacatacaat acccatttca
     9301 cttaattttt caataagttc ttctctactt attttaagtg tattcgttct tatatagata
     9361 ctaggctttt cattatttgc ttccaacaaa tcttcagcaa attcttgtcc aaatttatct
     9421 atccagtttt ttataatcca agagttatag gaatacttta tagataagta ttttacacta
     9481 tcttcctcag ttatgtccat tatagtctct ttagctctta tttcatttct aagaatagca
     9541 tttatgaaac cagaagattt tttatcatat ttcttagata attttacagt ttcattaact
     9601 gctgcataat ctgatatact atctaaaaat aaaatctgat atgttcccat tcttaaaaag
     9661 attttaacat aagttgacat tttttttacc tttatttttg aaagtttatt gattatataa
     9721 tctaaataat atttattttc tattactcca taaattaact ctgttgcaag tcctctatcc
     9781 atatcactta tttctaaatt tttaaaatgc ttatttattg caatatttga ataattgtca
     9841 tttttttcta tatcacataa tactttaaat ccaacttctc ttgcatccat ataaatttct
     9901 cccttttatt aaacataaaa aagggttgtt tctaaacaac ccactttact tttagtcatt
     9961 tcttctttga gctattagta acaatctaag taattgaagt attgaaacca atgctgctgc
    10021 aacatatgtt aaagctgctg ctgaaagtac tcttctactt tgtcttgact cactttcatc
    10081 tataatccct aaattcccaa gttgaacgat tgctctactt gaagcattaa attctacagg
    10141 caatgttatt atttggaata acactgaagc cgaaaacaat agtataccaa tttttaaaaa
    10201 tggaccagcc ataataaatc ctaaaaatat taaaaaccaa gatatacttg aagcaaaatt
    10261 cactactggt actaaactac ttcttatttg aagaggtgca taacctttag catgttgtat
    10321 ggcatgacca cactcatgtg cagctactgc aacagaagtt atagatgttc cataatatac
    10381 atcttctgac aaccttacag cctttcttct tgggtcataa tggtcactta gatgccctct
    10441 aaccatttct atctttacat catacaaacc atttgaatca agtactcttc ttgctgtttg
    10501 ctctccagta tatcctcgac gtgtatttac tcttaaatac ttatttgttg ttgaactcac
    10561 tttaaattgt gcatatatag taagtaatat agctggaatt aatacaacca ttgttgggtc
    10621 aaatccccaa aaaccgccat atacagggta cataaataac actctcctaa aatatatttt
    10681 tattatacat cctcttaata ttcacttcac ttaaaaacag tttaattaca aactaatata
    10741 ttttttcctg ttaaaaagcc tatagctttt tcaatatcca taatgtctac attagtattt
    10801 acacaaggtc cattaggtct tttgttaaat acacctaaaa caggaatttt cttaatatct
    10861 tgtattccag atgtcaaatc tctttcacat gcaacagcta caacagcttt aggtttatta
    10921 tccattataa tttttctagc tagggttcct ccagtagcta caaatatttt tacattagtt
    10981 ttttccttta gcttaattaa ttctcctatg ttgcatcttc cacattcttt acaattatct
    11041 atatcattag taacttttaa tttacaacta ttctcttgaa tacaatgagg tattaaaatt
    11101 attatatcct ctggattaaa attatattta ttactgtata tatattcatt atttaacttt
    11161 atatatattc ttctaatatc actttttgac ataccaaatg atgatgcaat gaaagatata
    11221 ataggaaata atccactgac aatattaaaa tttattttca ttatatttga gttaacatac
    11281 tttcctttaa ttactctata agtaactgct gttgaacata gtattataag tattagtgat
    11341 attattataa tatttatcat caaggagaat atttgagtta aacttattat aaaaaaatta
    11401 acaactccta tcaaaattcc taatattaaa atcaaaatcc caacacttgt taaatacttc
    11461 tttatatctg tcatactttt cacctaaccc aatactaaac cagtttctat agtattccct
    11521 tttatatatt caccaaccaa cattctcttt ttattcggca tctgaatttc ttcaattaaa
    11581 agtacattat ctatagtact tacttttatc ccatctttgc ttacatcaat tattgtacct
    11641 acatcttttg tgcttttttc atctaacact ttagttttcc aaactttcat tatgacatca
    11701 ttataggtag tataggcact tggccatgga tttactcctc taactaaatt gtgtatttct
    11761 ctggcacttt ttgaaaaatc tatgttacct aatgatttat tcattattgg cgcataggaa
    11821 aattcttcat gattttgtac ttctcttgga gcatttcctt cttcaattaa tcttaatgtt
    11881 tcttttaaag tttctgcgcc tatattcatc attttatcat gaagttctcc tgctgttata
    11941 ttttcatcaa gatttacttc tgtctttagt atcatatctc cagtatctag cccttcatcc
    12001 atatacatag ttgtaacacc agtcttttct tcaccattta ttattaccca atttataggt
    12061 gccgcacctc tatattttgg aagtaaagaa acatgaacat ttatacatcc aagtttagga
    12121 atctctaata tttcttttgg aagtatctgt ccaaaagcta caactactat tacatctgga
    12181 tttaaagatt taattttatc tataaattct ttatctctag cctttactgg ttgatataca
    12241 ggtatattat tttcaattgc cagttctttt actggactca tacctagttt tttacctctt
    12301 ccttttggtt tatctggttg agttacaaca cccaatattt catacttctc atctattatt
    12361 ttttgtaaac atggaactgc tatatcagga gttcccataa atactatttt catcaaatca
    12421 actcctacta cttttctatt ttgtcaacaa acaaaattcc atctaagtgg tctatctcat
    12481 gacaaaatgc tctagctaaa agttcttctc cctctaactc tattgtttca ccatttctat
    12541 ttaaagctct gacctttaca taatttggtc ttctaacatt tcccgcttct ccaacaacac
    12601 ttaaacatcc ttcctcatct atttgctccc cagatgtttc tattatttca ggatttataa
    12661 gttctataag ctcttctcca atatctatta ctactactct ttttaatatt ccaacttgag
    12721 gtgcagccag tccaacacca tctgcatcat acatagtttc tgccatatca tctaataatt
    12781 gtattatctt ttcatcaatt ttttcaacct tttttgattt ttttcttaat actggttctc
    12841 ctatttgaac tatttgtctt aaagccatta taattcctcc taaatttata atacactgtt
    12901 tggattaata tctatagata cattgatatt cttatcaaat atcaaatctc gttttgttat
    12961 acatatatat tttattatac cctttaagag attaatttca atattttcat ctttaaagag
    13021 tatttgccat ctataatttt gatttatttt tgatattgaa catggatttg gacctaatat
    13081 aaatcctaaa tcatttatac cccttttttc taataaataa atcaatgatg catgcatatt
    13141 ttttatattt tttatcacta gtctttcatc ttcaccacta acaactacac ttaacatatt
    13201 attaaaagga gaatatccaa atgcttttct tatttttatc tcatcttcat aaaaaccctc
    13261 ataatcatat tcaatagcat gcttaatagc atagtgttca gtgtcataag tctgaagtac
    13321 tacttttccc tctttatcag ctctccctgc tcttccagag acttgagtta tcaattgaaa
    13381 tgtagtttca aaacttttaa agtctggaaa atttaatatc atgtctgcag acaaaatacc
    13441 tactaaagtt acattctcaa aatccagccc tttacttaac atctgtgttc caataagtac
    13501 atctgcttct ttatctttaa atttatttag tatctcatct aaagcacctt tttttgaagt
    13561 tgtatcttta tccattctca aagtttttat atctggaaaa atatatttta attcctcttc
    13621 aattttttga gttccaactc caaatggctt aacataagta cttttacatt caggacactc
    13681 ttttggaatt tctttctcat atccacaata gtggcatctt ccagtattgc ttttcttatg
    13741 ataagttaaa gatatatcac aattttcaca ttgaaacaca tatccacact ttctacaaga
    13801 tacaaaattt gcataacctc ttctgtttaa aaatagtatt acttgattat tttcttcaat
    13861 cgcataacgt atttcttttt gtaatttcaa actaaatata cttctatttc ctttatctaa
    13921 ctcatctttc atgtctacca cttcaatgtt tggaagaggc ttatcatttg ctctactttt
    13981 tatatttata agtttgtatt ctccagattt tgccctataa tactcttcaa ttgagggcgt
    14041 tgctgaacct aaaataagag ttatattatt ttttaatgcc ataaatctag caacttctat
    14101 agcattaaat tttggattct tctcagactt atatgatgac tcatgacatt catcaattat
    14161 tattaagcct aaggaattaa aaggtgcaaa taaagctgac ctagctccaa ttaacactct
    14221 tactttacct gctttgacag ctttgtaaac atcatgtttt tctccttcag atagtttact
    14281 gtggaacact ccaaccaaat ctccaaacct actctttagc ctatctattg tttgaggagt
    14341 taatgctatc tcaggtacta agaatatact gtctaagcct tgatttagag caaattctat
    14401 tatttccatg taaacttcag tttttccact tccagttact ccatgaatta agtatggttt
    14461 tttatcatct acaaacatat tcgactttat ctcatcaact gcttcttgtt gctcattgtt
    14521 taattttata ctttttagta cggatttgta aatacttttt ggctctctat aataatcctt
    14581 aaattctagg gttattagct ttttcttact tagagaattt atactttgtt ttgaagcatt
    14641 taataaatcc aataaatcat ttatctctac attttcatta tttttaagaa aacttaatat
    14701 ctctttttgt ttacttccca catttatttt attttgctct atataatcgt caatcttatc
    14761 actttctaaa ctcaaagata tataacatac cttcttttca tttttgtgat ttttatattc
    14821 ccaacataat tttataattc cattcttatt cattgtgtac aaagaactat ttaagtttgg
    14881 tatatatttt aacttatcaa ccttaatttt acctttacta tcaatcactt tctctactat
    14941 ttctctattt ttatcactta aagttgatat tttttccttc aattcaatat catttaatcc
    15001 acttaaactt tcacctaata ggactacttt ataattattt aatttgtatc cctttggata
    15061 tatcaaattt atacattcta tataagtaca caaatatcta tttttcatcc aataaaccaa
    15121 ctctaaatct tcttttctaa atatcggatt ttcatctaat atatcaataa tttcttttat
    15181 ttttattttt tcatctaagc tatctgtaaa ttgaaataca aaggcttctg ttggtttatt
    15241 accttttcca aatggtacta atattctgtg cccaattttt attacatcag ataaaaatac
    15301 aggaatttga tatgtaaata aattatctgt atatatagta ttacttctaa ctattacctt
    15361 tgcatatttt ttcattataa aacctctact taaatttaat atattgttca tattttaata
    15421 tactttacaa gatattaaaa tctcagaatt tataagcaat ttcaagttat taatattaac
    15481 tttattttaa taattaacta ttaattatat tttatacttt atgacaaaat aaatgctgaa
    15541 aactacaatt taactgacat ttgcgagttt ttactcgcta aaattgaatt gcagctttca
    15601 gccactttag ctgtgataaa atacacaaat atcatattta aaaaaggtct tatttctcaa
    15661 gcaacgcttt aactttatct aaaataacat tggctacttc ttcttttttc atcttaggat
    15721 actcagtaat atttccctct acatctatta tttttacaat attagtatca gctctaaaac
    15781 cagcaccttc tttagttaaa tcatttgcca caataaaatc taaatttttc ttttttattt
    15841 ttcctttggc atgttctata aggtcattag tttcagctgc aaatccaatt agtatcttat
    15901 cttcttttat ttttcctatt tcataagcaa tatcataatt tctacttagt tctattgata
    15961 aatcatcatt cttcttttta atttttttgt cagaataagt ttttggttta taatctgcaa
    16021 ctgctgcact ttgaattact attttatttt cacttaaatt tgatactact gcttcataca
    16081 aatcttgtgc tgactctatt tgaacaaatt ttttaagatt ttgtggaata gaaagatttg
    16141 taggacctga tattaatgtt acatcagcac ctctagctat agcttctctt gctatagaat
    16201 atcccatttt accagaagac ctattagtta aatatcttac tgggtctata ctctctacag
    16261 ttggaccagc tgtaactatc atactttgac cttttaaatc ttgctcttta gtaagattag
    16321 tcaaaacttc ctctactatt atatctggat tagctagttt acctgttcca atatctccac
    16381 atgcaagcct tccactttcc ggttcaataa atttatatcc aaagctcttt aaagtttgta
    16441 tatttttttg aacaattgga ttttcataca tattagtatt catagctggt gctataagaa
    16501 cctgtgcttt tgttgccata acagtagttg tcaacatatc gtcagctata ccatttgcaa
    16561 tcttgcctat aacatttgca cttgctggca ctattaagaa taaatctgct ttttttgcta
    16621 atgatatatg ttcaacttcc caagtttttg gttcttcaaa catatcttct actacataat
    16681 tttgactcag cgattgaaat gtaagtggtt taacaaattc tgttgctgat tttgtcatta
    16741 taacatggat atttgcattt agttttttta acttacttac aacatcacaa gccttatatg
    16801 cagctatacc gccacttatg ccaattacaa cagttttatc ttttagcatg accttactcc
    16861 tcttctgaaa tttgttggtg ttgctcagca tgatgtctag cttcttctat ctctatttcc
    16921 tcttctgtca ataatctata tgttattttt ccacttgcaa cttctttagt tgctacacat
    16981 acaggctttt ccttagtttt atttgaaaca tatggttctt ctccatcaat taattttctt
    17041 gctctctttg aaacagtccc tactaaatag tatctgttgt ctattttttc tagtacctca
    17101 ttgatagatg gttttaacat aattataatt cctccttaaa tttctctatt ataatatttt
    17161 tatatctgct aactttattc ttttcagatg atattatacc ttctatttct ttagcagatg
    17221 tttttacatc ttcattaaat ataaaataat cataatcctt aatcatttta atttcttcat
    17281 atgcacagct aaatctcttc tctatttcag cttctgtttc tgtacctctt ccaacaattc
    17341 tattttttaa ttctttaagt gatggtggta gtacaaatat aaatactccc tctgggcaaa
    17401 cttcttttat ttgttttgct ccttgcattt caatctccag taatacatct tgtccttttt
    17461 ctaaacattc cattattgcc gcttttggag ttccataaaa attatcataa atttgagcat
    17521 actccaaaaa ctcacctttt tctatcatct cttcaaactt ttccttactt atgaagaaat
    17581 aatttactcc atcaacttct ccagttctgg gttttcttgt agtagctgat acagaaagtt
    17641 ttattgtatc attttcttta agtagttctt tgcaaatagt accttttcct gcacctgatg
    17701 gtcctgatac aactagcaat aatccttttt tcacaaacat ttaagcattc cccttctaat
    17761 attgtattct tactctatat tttgtatttg ttctcttatt ttttccaatt cgctttttac
    17821 ttctactact aaattagtta tatttatatc agatgacttc gaacctatag tgttagtttc
    17881 tctattcatc tcttgtatta agaaatctat ttttctacct atagagtcgt ctttaaatat
    17941 agtattttta agttgcccta tatgactttt aaatctaact atttcttctg ttatactgct
    18001 tttatctgca tatattgcaa cttcttgtgc taatctattc tcatctatta tacttgggtc
    18061 atccagtaat tcacttattc tcaaattcaa tttttctcta taatcttcta caacactact
    18121 tgaatatttt tcaatctctt ctatatgatt ttttaataaa tcacatctca tggcaatatc
    18181 ttcagctaat tttttacctt cttcacttct catttctctt aatttgatta atgcatcttc
    18241 aactgcttga ttcaacattg accacaataa atcttcatct tcttcctttt cttctatttt
    18301 cacaatatca ggaaactttg caacattcat aacgctaata tcatctataa tatcaaattt
    18361 attttttatt tcttttagta tgtctatata ctgagatgct aatccctcat caaaatttaa
    18421 gtttacatct tctttgccta ataagtcaaa ctttatgtat aaatctactc ttcctctttt
    18481 tacataattt tttactaaat ttctaacttt atcctctaaa aatgaaattt ttcttggaag
    18541 acgtatgttt atatctgaat acttatgatt tatcgtttta cactctacta aaaagtaata
    18601 attatcatcc ttgtattctc ctcttccaaa accagtcata cttatagcca ttaattaaac
    18661 ctccaaaata ccttcacata tttttactgc tggacctgtc atataagaga aatctcctac
    18721 atctatttta actgttccac cttgagacgt tacatttaca ctactttcta ccatattaag
    18781 taaattgcac actattgctg atgcagtcat accagtacca caacctaaag tatatccaca
    18841 acctctttcc caagtataaa catgtatatt atacttatct tctaccttta caaaatttac
    18901 attcgttttt tcaggaaata ttttattatt ttcaatctct tttccatatt tacaaacatc
    18961 atctacatct aattcatcta ctataactac tgtatgagga acccccatca acatagaagt
    19021 aactttaagc tccctatcta aaacctttat actttcttgc acaaaacgtt ctttatttgt
    19081 aagtacagga acgtccttag ctataaaact tccttttccc atattgactc ttatagagtt
    19141 tatttctcta ttagtaagat ttacttttat atcttttata ccatctaatg tatctactgt
    19201 aaaactttct tttttaacta tacaattatc ataaacaaat ttacaaaaac atctaaggcc
    19261 atttccacac atagctgctc ttgaaccatc agaattataa tataccattt ctacatctgc
    19321 aacttttgaa tctttcacaa ctaacaatcc atccgctcct acagaaaatc ttctatggca
    19381 tacttttttt gctaaagcag tataatcaga tggatttatc tggtcgaatc ttccatctat
    19441 tgctataaaa tcatttccta ttccatgtag tttccaaaat ttcataagta tcgctccttc
    19501 gtaaattaac acttaaacta ttataacata aaaaaattcc cataaactta taatttatgg
    19561 gaaaagtttt gtaatgacaa ctataatttg aggatgtgag ggagagttgc cattacaatt
    19621 agggtaatta tattatgttt ttaagctagt tctttctatg tttatatatt aatatttcta
    19681 tatgaatttt atgtatgttt tatttaaact gtctatgaat tttttaatta aacatctggt
    19741 aactagctat aatccttcta gtagatatct attaacatac acctattaat tctttaagtg
    19801 tttttaaaac atagtctaaa tcttccttag taatatctac atgagttaca aatctatatt
    19861 caccattttc cattttatta atttttatat ttctttcaaa aaattctttt attaaaacat
    19921 cctcttttat aatatcttca ctcatcttaa aaaataccat acttatatct ggattaacat
    19981 tgtttacttc aatgccatca attttattta attcacaagc taaatatttt gcattttcat
    20041 ggtcttcatt caatcttaaa gtcatttttt caatggcaat tataccagct gctgcaacta
    20101 tacctacttg tctcattcct ccacccataa ctttttgctt tcttctagct tttgctataa
    20161 attctttatt tccagcaagt atagaaccca ttggtgcagc taaacctttt gacacacaga
    20221 acataacact atcacaacac tttgctattt ctttagcttc tacacccaaa gttaatgctg
    20281 cgttaaataa tcttgctcca tctaaatgta ctggtaagtt atgtttctca gctatttttt
    20341 taatttctct taaattatca agactcacaa ctgttccacc tgaatatgca ttttctacac
    20401 atataagccc tgtctgtggt tcatgtatgt catctcttct aattgccttt tcaacaagtt
    20461 caggatttag agctccactt tcgtcttcat ctatagttct aagctgaact ccagctatta
    20521 cagcaggtgc cccaacctca tgagtcacaa tgtgataacc tttaccaata attatttctt
    20581 gccctcttag gcaatgagta aatagagcta attgattccc aaaagttcca cttggaagga
    20641 aaatagcatc ttcttttcca actttagctg ctgctaattc ttcaagttta tttacagtag
    20701 ggtcatctct aaagattgaa tctccaacag gagcctttgc catagcttct ctcatttcgt
    20761 cagtaggcat agtaacagta tcacttctta aatcgataaa tctcattttt tcaaccttct
    20821 ttcatattta tatactatag aaccttaaaa ttgatttttt ctgtaaagtt catatacttt
    20881 catagcttat actctacaca ataattatac tatatttact ttatatttaa tctactttaa
    20941 attattaatt ttaaaaataa agtttcctct ctaataaata taaataatta tacaatttaa
    21001 atattaatct ctattgttta aattccccct agtcacaaag cgtatattat gtgtataatt
    21061 aatttactga ctcattttgg tcaaagaaag gggtgctata aatggcatta gatggattag
    21121 ttatacattc aatagtcgat gaattatcat caaaacttac aggtggaaaa atagataaga
    21181 tacatcaacc tgaagatgat gaggtaattt ttaatataag aaataataaa gaaaatttta
    21241 gattggtttt aagtgcaagt gcctcaaatc ctagagttta tcttacaagt aattatcaaa
    21301 aagaaaaccc tctaaaagcg cctatgtttt gtatgttact tagaaaatac atacaaggtg
    21361 gaaatatagt agaaatttct caaataggtt ttgaaagaat aataaaaata agtgttgaat
    21421 ctttagatga attaaaagaa aagacagtta aaaatattat gattgaaatt atgggaagac
    21481 atagcaacat aataataact catggtgaag aaaataaaat tatagattct ataaaaagag
    21541 tcccttttag cataagtaga gttcgtcaag ttttacctgg tcatgattat tcattgccac
    21601 cagaacaaaa caaactcaac cctcttgatg atatatctaa ggatttgttt attaaaaacc
    21661 tagaggaatt ggaaggacct atctttaagt ctatatattc taaatttcta ggtataagcc
    21721 ctattatagc taaagaaatt tgctacagag caggtgtaaa tcaaaatgct atcataaagg
    21781 atatatctga tgaacaattt gattctttac acaaagtatt ttgtaattta ttcaatgata
    21841 taaattctaa caaatactct ccttgcatta ttatagataa aaaggtggat aaggtagttg
    21901 atttcagttg tataaacctt acattattta gcgatttatc atatataaat aaggatagta
    21961 tgtctcgtat tctggaagat ttctatagaa ctaaggatat taaagataga attaatcaac
    22021 gttcatctga tttaaagaag agtatatctg ttaagcttga tagactttat aataaactta
    22081 aaaaacaaga agaagaatta tcagaatccg aaaatgcaga catttataag ataaaaggag
    22141 aattgattac ttcatatatt tatatggtag aaaaaggtat ggaaagtatt gaagttgcta
    22201 acttctatga tgaaaattgt aatgatgtaa caatagaatt aaataaaaac ttgacaccat
    22261 ctgaaaatgc tcaaaaatac tttaaaaagt ataacaaaat gaaacatgct aaagtcgaga
    22321 tatctcatca aatttcctta aataaggaag aaatagatta cttagaaaac ataattttaa
    22381 gtattgaaaa ctgtgaaaat ttagctgaat tacaagatat aaaagaagaa cttgctaagg
    22441 ttggatacat caagactcaa aagaaaaaca gtaaaaagga tactatccca tctacaaaac
    22501 ctcatgaatt tgtttcttct gatggattta aaatattggt tggtaaaaac aataagcaaa
    22561 atgactatct tacactaaga cttgctgata atgatgactt atggatgcat acaaagaata
    22621 ttcctggttc tcatgtaata ataaagtgtg ctggtaagga agtccctgat aatactgtat
    22681 ttgaaggagc tatgctagca gcattcttta gtaagtcaaa actttcttct caggtgcctg
    22741 tagactatac taagagaaaa aatgtgaaaa aacctagtgg ttctaaacca ggtatggtta
    22801 tttatgaaac taacagtact atttatgtta ctcctgaaga agaaacagta gccaagctta
    22861 aggttaaatc tgaataaatt ctgcactaaa tacaaaataa atgttagaca actacacatt
    22921 atcattctaa ataaaaatag tggccttctt ataaagtaca ataataaggc cactttctaa
    22981 ttagcttact tttaattttc taacaaaata cttttctgtt ttaataacta tacttatatt
    23041 cccaacaaat attttcagtc ttcttatata gatgtaatta aaaagttaac actaaaagct
    23101 attttttaat ttattgattt gttttagtaa ttcattatat tctgattcat acaattcttt
    23161 ttttagatta tctttttcta tagataacat agatataaca gttgtaagtc tattttctaa
    23221 tactagaaga ttttcttttt tgatttggtt ttctctacta ggagtttttt tatttctgct
    23281 aattgtatat tcgtcataat tacaatcaaa ctcccttatt ttagcatctt ttatctctat
    23341 aatatagtta caaatatgtg atacaaatac tctatcatga gacactataa gcatagtttt
    23401 atcagtattt atcagtgcct tttccagtgc ttccatagat tttatatcta agtaatttgt
    23461 tggttcatca aatactaaaa aattattatc ttccaatatt attttacata gtgctatttt
    23521 taccttttct ccaccactaa gtacttttac ttttttgtag acatcatcac ctttaaaccc
    23581 aaataggctt aagtttatcc ttataaaaga ttcatcaaat gaactattaa ctttagtatt
    23641 gtatagaaca ctcttttcct catctaataa actttgattt tggtcaaaat aacctacttt
    23701 taccttgtta tttattttta tattgtcatt tttatcagcc aatatttctt ttatcagagt
    23761 actttttcca cacccattat cacctaataa tgctatcttt ttacctcttt ttatcttaaa
    23821 ggaaacatta tctaacagga gcttattttc taactttaga gtcatatctt ttacctctac
    23881 tagattttta ctaattatct ccataccatc ttgaatctta atgttcattt ctttagaaac
    23941 tttaggttta ttctttacct caagtttatc aattctgctt tttatagcct tcacatttga
    24001 gtccaacttt ttcttattag tctgaccacc cattttgtgc aacctagctt ctgaattacc
    24061 cattcttttt ggtgtttttc ttatgccatc acttaaagct tttttatata aaagagcttt
    24121 ttcaagcctt tttttctctt taacatattc ttgatactca aaatcagctc tttttacttc
    24181 ttcatctttt tgcattaaat aatcagtgta attgcctttg taagctttta gttttccatc
    24241 ttctagttct aatatagttg tacataactc atccagaaaa cgtctatcat gagatattaa
    24301 taataatgct ccctcatgcc ttttaaacat atcttccaaa accccaatgc tttttttatc
    24361 taagtttgaa gttggctcat cagctattat gatatttttc ttattactca gcgcatctgc
    24421 tatttttaac ttaacctttt cccctcctga taagtgttct tcaaatttat ctggagcatt
    24481 taaaagactc ttctccttac tatgactaca tgtttcaata ttattttcac tctgacttat
    24541 ataagaatag ctttctgtaa ggtaagtata tccttcatca atttctattt ctcccaatat
    24601 tgcttttaat aatgttgttt ttccttgacc atttgaacca actagaccta ttttgtcatt
    24661 ttctaatatt tcaagtttat ctatatccaa aattaattta tctgcataat atttctttaa
    24721 attctctact tttactaaca acataaaaaa tccctcctta acacacttaa atataaggag
    24781 agattctata aataggcata acaaataaac gtatagacta taatctactc tccttaattt
    24841 aagcattgca aataaagcca ccaaaatagg cttttcaaaa attacaatac tttaaattat
    24901 aaaaaataga ttatattctc attgtcctag ttaccttgcc ctttctttca tttattttta
    24961 atcattatat caacattaat tacaaatgtc tatagaaaat taactaattt tagttattca
    25021 atatacaact tattctttaa atttattctt cttcaacttt aaagtcctga ttatttaaaa
    25081 ttctgtttaa tacaattcca acaattgcag ctaaactaag accagttatc tttactgtac
    25141 ttgttatagg gattccaaca gaaatacctt tattagataa atatgttgtt ccaagaccta
    25201 ttaataatat aactgctatg attaatatat ttattttact ttctacacaa gaactgtccc
    25261 ttatagtttt taatcctaca taagttatca tcgaaaatag cattatacta attccaccca
    25321 taactgaacc tggtatactt tgaagaaatc caccaaactt gcctacacat gcaagcaata
    25381 tagcaaatat tgctgtacgt ctaagtattg aagggtcata gtttttagtt atagcaagta
    25441 ctgctgtatt ttctccataa gttgtatttg ctggtcctcc taaacaccct gcaactatag
    25501 tcgcaaatcc atccccaagt aatgttctat ttaatccagg attttctata aagtttttac
    25561 ctactacagc accattagta gtcatatctc ctatatgttc cataaataca gctaatacaa
    25621 ctggagatat aatcactatt gctcctaaac tgaacttagg aactgtaaag ttaggtattg
    25681 caaataaact tgcttctgta atagtagtta tatctactaa tcttaatatc aaacagatta
    25741 tatacccaga aaaaactgct attaatattc ctaattgttt tataaatcct ctaccaaact
    25801 tattggttaa aattgctatt gctaaagtta taaatgctat cacaaaattg gctgaagcca
    25861 tactaaaagc tgttggcaat aaatttaatc ctataactac tatcatagct cctgtaactt
    25921 gtgcaggaaa atataattta attttattta caccaactac ttttactata atcgacatta
    25981 taatataaat taatcctgct actattatac caccttgagc atatgctaaa tctccaccat
    26041 acgcctcttt agctgctagt ataactggta taaacgcaaa acttgaacct aaaaaggcag
    26101 gtacttttcc ttctgtacaa aaatgaaata tcaatgtacc aacaccagca cagaaaattg
    26161 caactgacgg attaaaacct gtcaaaatgg gaactaatac tgtcgctcca aacatggcta
    26221 atagatgttg taaagacatt atcgtttttt tcataaaaac ctccaaaatt attatatata
    26281 aataaatcct ctgtttaatt aatacctttt aattaattat cattccctag attctatttt
    26341 ttaacctcta tatacttatt atataattta tcattatttt acattttacg acatcaaaaa
    26401 ctcaaataaa ggagaataaa aactacatta agactcacat ccataaaatt ataatattta
    26461 ttttgtgcaa tctatgtaag ctttatcctc ctccctgact attcaatgct aagcttttat
    26521 ataatactta aaaataatta ttctttgatt gtaactgaat cttctccatc aatttctaat
    26581 aaactgacag atataatttc atgtctagaa gtaggtacat tttttcctac ataatctgct
    26641 cttataggca actctctatg ccctctgtcc actagcactg ctaattgtat tgatttaggt
    26701 cttcctatat ctataatagc atctagtgaa gctctcacag ttcttccagt gtataaaaca
    26761 tcatcaacta aaactactgt cttatcattt acattaaaat ctaaataagt tcctttaact
    26821 acaggttcaa catgaatttt ttccaaatca tctctataca aagttatatc aatatctcct
    26881 gtatctactt ttgttccttc tatttgttct attttcttag aaattctatt tgcaattggc
    26941 acacctctag tctttattcc aactaaaact agattttcta cacctttatt tctttcaatt
    27001 atttcatgac ttattctagt aattgctctt gctattgcct tttcatccat taattgagct
    27061 ttttctacca tatcataatt attgtcaaag atataatata tctatttgac aaatctactc
    27121 ctttctttta attttttata aatttatttt tatttaaaat ttcaatttaa acaacaaaaa
    27181 aacttctcat cacaagacaa gaagctctta tataaaaaat atacagtgta atttagcaat
    27241 tgtcttacga tatctctgta tcgtttaaag ataatttttt aatctatcaa ctcaaattat
    27301 atatttatat ttcaaatttt tcaagctttt ttaaacaaaa tactttaata taagatattt
    27361 tatttaaatt tcactaaatt tatttactta tataaaaaca aaaaatgatt tataagtatt
    27421 atacaaatgg ttattttatc tttttaataa cttccttaaa atactcaggt aattctgaat
    27481 taaattcgat atattcctta gtagtaggat gtataaatcc caacttctta gcgtgcaaag
    27541 tttgtccttt taatttaaat ttagtttctt ttggaccata tacataatca cctaaaagtg
    27601 ggtgatttat agacaaagca tgaactctta tttgatgagt tctaccagtt tcaagcctag
    27661 ctctcatatg tgtaaactta tcaaatcttt ctacaacttc aaagtgagtg attgcatttt
    27721 ttccatcttt tactacagcc atttttaatc tatccttagg atttctccct ataggtttat
    27781 caacagttat tttatcttct ttaaccacac catagcatat aaattcatac tccctagtta
    27841 tagtatgttc ctttaactgt tctgctagaa aattatgtgc ataattgttc ttagctatca
    27901 taagaagacc agaagtatct ttgtctattc tatgaactat accaggtcta ataactccat
    27961 ttattgatga caacttatct ttacaatgat ataaaatccc atttactaac gtattttcat
    28021 agtttccagg agcaggatgg acaaccatat cctgaggttt atttattatt aagacatcat
    28081 catcttcata tacaatatct attggaatat cttgaggtaa aacttctaat actttaggtt
    28141 ctggtatctc tataacaata ttatcttcct ctttaaccag atatctagct ttttctactt
    28201 tattattaac ctttactttt ccatctttta taattttttg tatataactt cttgacatat
    28261 cacctaattg ttctgctaga taaatatcaa gtctaacttc ttcttcctct tcaagtacta
    28321 aaaactcttt tacttcatcc attatatcac ctacttttac tttcaaaaaa taaaacatat
    28381 atacataaaa acacagttcc tacaactaca aatacatcag ctacattgaa tacatattcc
    28441 catataactc taaagtcgaa gtaatctacc acaaaaccta atcgtactct atcaactaga
    28501 tttcccaatg caccagatat aattaatata attcccaacc ttccaaatat atgtactttc
    28561 cttgtattaa gatagtataa tccaaatacc gttgcaagta atgcaacaat tataaatatc
    28621 cattgattat tttgtaataa tccaaatgct gcacctctat tttcgacata agttaaatga
    28681 aatacattat ttattattgg tattgttgat acatccacca aattattcaa tacccatatt
    28741 ttagacagtt ggtctaaacc tatgagtaga attattatta atatatatag caatgatttt
    28801 tccccctata aattatttaa aaaccaattt tatttgaagc acactattat tattatacaa
    28861 aaaaaatgct ctaaagagca actttattaa aattgtattt tcttaataaa gctagaacaa
    28921 aatttaaaat agtactactt tttttatatt gtagatttct acatatttaa aatcatatca
    28981 ttatgtataa aaaatttaaa aataccatac taatcaatat tttttgtgta ttttatagat
    29041 taaagattaa tgatgtctgt aatttaaact tacaatcacc actaatcttc aaacaaatat
    29101 ttttactttt gcacttgctt atttttatct aaatgttgta taagttcaga tactgttacg
    29161 aatttatatc ctctctcttt taatttagga attactactt ctaaagcttg tatagtttgt
    29221 gatttatcat ttcttttagt gttataatca tgtaaaagta ttatattacc attttggacc
    29281 tttgtaagga tagtatttat aattgcatct actccagggt tagaccaatc tctagggtct
    29341 aagtttgacc aaagaattat attcattcct ttagaaacta taatatcaca gacactttta
    29401 ctcatggctc tatatggagg tctaaatatc tttggttcta ctcctatcac actttttata
    29461 atattttgcg tatctgttat ttctttttca acactactat aactattttt tgcaacattt
    29521 atatgtgtaa atgtatgatt ccctatttca tgcccctcat catattgtct ttttaataat
    29581 tctttgttat attctacttt ttctccaact acaaaaaaag ttgcttttac atcatttttc
    29641 tttaatatat caagtacttg tggtgtaaaa tcctcatctg gaccatcatc aaaagtcaat
    29701 gctaaaattt tttcatcctc atttcctttt tttattatta catcttcata atcgtctttt
    29761 atattgtcat ttaaactata tgcttctttt gaactatctt gattatgtgt attatgatta
    29821 tatgtatata cacctactat agataataaa catatacata taccacatat tattttcttc
    29881 atgtcattac ctcttttcta attcattcta gcaatatatt ttataatgtc agttttttaa
    29941 tctctcaata ttccattttt atttaaatca gttaaatttg ttaggtcttc tgaataaaag
    30001 ttagaatctt ctacatcagg gttttgcatt gcatcaccta ataaattatt ttccttcttt
    30061 gcacaatcat tacataaact tgtatctggc aatatatcca atctttctaa atctatttga
    30121 ttatgacata aatcacaaat cccatatgtt ccattctcta ttttagataa tgctaagtct
    30181 atttgataca atcttccctc ttcatgattt attagactgt tttgcatatt ttgcatatat
    30241 aaatctgttc ccatgtctcc tatatgatta tcataactag ataattctcc tgatgaatac
    30301 ttttcacttg tatgtttagt tgtatctcca aataaagtat tatctttcat atcctctact
    30361 aaattagtta aattttctct ttctttcaat aatttatctt tatatttttt agtatccatt
    30421 tttaacacct ctaattttaa tatttacatc ataaaaatag tatgtggaaa agtaaattaa
    30481 acatacaata aaaataagat ttgattcgaa aaatggaatg tctcaaaatg aaatttttag
    30541 ttcatttaac cctctttttt atatgaaatc aaatatattt ttatcctttc agcaataaaa
    30601 aagagactta tctctatttt gagatagtct cttctttgaa cataatttaa atacaatttt
    30661 ttaattttta tagttattat tttactaact tgccaattta tgattatttt gttctttaat
    30721 atgttttgct tttttaaaga ataaaagacc aagaattatt gctacaataa cacctattcc
    30781 attagatata ttaactggta gtctaaatcc ttcttttgct tgcattatat aactaaatgt
    30841 tactacagtc ataaaaagtg ctggtaatgt agttatataa tggtttttat ttgctttgac
    30901 taaatatgca gaaccagtcc acaacattat cattgcaagt gtttgatttg cccaagagaa
    30961 atatctccaa attatattaa aatctataaa tgtaagagca acaccaactg cgaataatgg
    31021 taaagctatt aaaaatctat ttttgactgc atcttgatta taattcattg catctgctat
    31081 tgtcagccta gcacttctaa atgctgtatc tccagaagtt ataggacatg ccacaactcc
    31141 aagtatagct aaagctcctc caataggccc cattaatcca acagatactg tatttactac
    31201 tgttgctgct ccaccatcat taaatatcac attaagttga ggtatgccat ggaaatatga
    31261 catggctgct gctgcccaaa ctaaagctat tataccttct gcaaccattg acccataaaa
    31321 tactggtctt gcctcactct ctttctcaac acatctcgcc ataagtggtg attgagttgc
    31381 atgaaaacct gatattgctc cacatgctat tgttataaat aagtatggga ataaaggtgt
    31441 tccatttgga ttcatatttt gtaaatttat atttggtatg ttatacccct ttattattaa
    31501 tcctccagct acacctactg ccataattaa taatgctgct ccaaataaag gatatatttt
    31561 accaatcaat ttatctattg gtaaaacagt agccataata taataaagta ttatcactcc
    31621 aacccatatt tgtgcgttta cacctgtcaa tgtctttaat aatcctgctg gacctgttac
    31681 aaatacaact ccaaccaata ctaaaagaat aacactaaat attctcattg ctatttttgc
    31741 accatttcct agataaaggc ctaccaactc tgatgcagat gtacctttgt ttttcattga
    31801 tagatatcct gaagcaaaat cgtgtactcc accagcaaag attgttccaa acacaatcca
    31861 taaaaatgct gatggtccaa ataatgctcc ttgtatagct ccaaatatcg gacctaaccc
    31921 tgctatattt agaaactgaa ttaaaaagat tctcttccat ttcattggca cataatctac
    31981 tccatcccta caagctatag ctggagtttg atttttgtca ttggttccaa aaaccttttc
    32041 tacaaaagta ccatagacaa aataacctac tataagtact actattgaac ctaaaaagct
    32101 taccataaat tcatcccctt agtttttata taattgcttt ataaattttt atgagtttaa
    32161 gaaaactatt tccagttcaa atagtaatac ttttttatgc taatataaat attaattaca
    32221 ttaagtgcat atttaagtac atgaaatgac tttatatatg cattaacagc ctaaattctt
    32281 ttactttgct tctacttaca gttacttcat aatcactatt ttttaatttt aatatgtatg
    32341 tattattaaa ccatggtata atttctttta ctttggttaa gtttacgata taagacctat
    32401 gtgttctaaa aaatgtttta tcatttataa gattttcgac ttcttatatg ccttctttta
    32461 atataaactt ttctttctca gtatatataa atgtctgcct ttcattagct tcacagtaat
    32521 atatatcatc aatatctatt acaactaatt tatcaccttt ccaaaggcta attttatgtg
    32581 ttatttcttc tatctcctga tttactgctt ccttcttata tttgtataaa ttactattta
    32641 cattaaatag ttcaatatca ctcatctcac ttttttctaa tttattcagc atagaaataa
    32701 ttctctcttc agaatatggt ttcaatatat aatcaaatac atccaaagaa aaagcatcta
    32761 ctgcataact ttcatatgct gttataaaaa caattttagg tcttgattta aactgattta
    32821 atgtttttgc aagtagcatt ccatcaagat gaggtatatt tatatctaaa aaaattacat
    32881 ctattttatt ttcctgaata aagtctaaca cctctatacc attggtaaat tcacttacta
    32941 cctcgattcc acttttattt tcaataaaat atctcaattc ctttcttgct ggaaattcat
    33001 cttccactat tatagctctc atacttctac tcctttacat aaaatactat caaagtccca
    33061 ttatctattc ttcttatatt aagccctctt ccatacatca gtttaagcct taaatgtaca
    33121 ttataaagcc caatcttatt ttctggcata ttatcttgat atacattatt tataatttcc
    33181 tcacttatac ctataccatt atcctctatt gatattctca cagtattttc taatgaatac
    33241 ggtaactttt ttatggatat tttcactaca ccagctctac cactttctaa aataccatgt
    33301 attattgcat tttccactaa tggttgtata atcaaacttg gaatctttat atttacatct
    33361 tctatatcat aagatacagt tagtaattct ccaaacctag ctttttctat ctctacaaaa
    33421 gatttaactt gttcaatctc tttatttata tcaattaagt tatcactata ttcaagatta
    33481 tatcttagat aagttgataa atttattatt aactctctag ccttatctgg actaaatctt
    33541 ataaatgaag ctattgtgtt tagggaatta aacaaaaaat gtggattaat ttgtctttga
    33601 agtgctttta tttctgcttt atttctcgct tctatatctt ttttatcttt ctcaatcccc
    33661 tctactatag atataacaaa tcctattcca atctgcccaa ctattaaagg taaatatatt
    33721 ccaccgatta tttgaattgc taaagaatgt ggatatgata ttaagtatat aagtaatata
    33781 gtaaaacttt cagaaatcat gcctaccaat attccataca ttactctatg ttgttttggt
    33841 atcctcttat atagaaatcc tgataataca cctgctagta tacttgataa aagacatgga
    33901 acagatgtta tccccccaat atccataaaa tatctatgaa tccctgaaaa aactcctgct
    33961 gtaataccta ccatcggacc aaataaaatg ccacctgata ctatagatat tattctagtg
    34021 tttactattg accccatata atttatacca ctataagttc caaatatggc taaaaaagta
    34081 aaaactaatg ctatacagac caagtcatta aaactatatt cttccttttg aaatatctgc
    34141 ttaaatattt ttaactttgt tattagaaga aacaatacta caataaggct tgtcttttct
    34201 attaatgcga ttaaaattga tgttttcata atcccccttt aaaaaataaa tttttacaca
    34261 ctctaaattt attatggttg ttataaatta catatttgaa gtaatcctat cacaaaactt
    34321 tccacattta atcttttaat taaataagaa atagttgtac ttctattaac aactaatact
    34381 agctagcata agcttgtaat aacttgtagt tattattaac tttacaattc tagtatttaa
    34441 ttttatactt tagaaatctc ttttcttaga aataatactt tcgaatatca tataatacaa
    34501 tattatgtag attcttactc atacaacata tttctttaaa aattttatac tattctttgt
    34561 tcaaatatct catttgattt aattgtgtta aacacacatt atcatctctc tgttatatat
    34621 ttattatata gccgtatatc gataaagtaa ataaatccca tatttaaaat aatatgtttg
    34681 acaataaatt attataatgt atatttacca taataatttg tcaaccttga aagttacttc
    34741 tataattatt gttaaataat tcttctaaaa aaaataccta taaattttat ttt
//
LOCUS       DAMJWC010000043        34510 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMJWC010000043 DAMJWC010000000
VERSION     DAMJWC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.043"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            8..580
                     /locus_tag="PC503_002348"
     CDS             8..580
                     /locus_tag="PC503_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDF2528319.1"
                     /translation="MKKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEAFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNSNYEFKDYLNYIT"
     gene            complement(1593..2255)
                     /locus_tag="PC503_002349"
     CDS             complement(1593..2255)
                     /locus_tag="PC503_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528320.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(2272..4827)
                     /locus_tag="PC503_002350"
     CDS             complement(2272..4827)
                     /locus_tag="PC503_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2528321.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPHDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLLRLMGAKKRNIRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGMISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLISVVVSNRDFESMNIIEGIKENE"
     gene            complement(5067..5255)
                     /locus_tag="PC503_002351"
     CDS             complement(5067..5255)
                     /locus_tag="PC503_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2528322.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTK"
     gene            complement(5267..5446)
                     /locus_tag="PC503_002352"
     CDS             complement(5267..5446)
                     /locus_tag="PC503_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528323.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEVNVEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(5451..5708)
                     /locus_tag="PC503_002353"
     CDS             complement(5451..5708)
                     /locus_tag="PC503_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528324.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKEKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            complement(5968..7361)
                     /locus_tag="PC503_002354"
                     /pseudo
     CDS             complement(5968..7361)
                     /locus_tag="PC503_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            complement(7355..8030)
                     /locus_tag="PC503_002355"
                     /pseudo
     CDS             complement(7355..8030)
                     /locus_tag="PC503_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(8579..10108)
                     /locus_tag="PC503_002356"
     CDS             complement(8579..10108)
                     /locus_tag="PC503_002356"
                     /inference="COORDINATES: protein motif:HMM:NF012862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HDF2528325.1"
                     /translation="MKSLKALIVGVSKYSIVKNKDLLFCKNDIIEINNVLHKRLGITS
                     NNIRTLGMEYEVRKDLFFKTFQEISDSIGDDDTFIFYFSGHGCICNNGVHYLVLSDEL
                     VSIQFVIDFIEGLNCKNKIVFIDCCFAGKFNVSDKQKINIKDIFSLFDRKGCAVLVSS
                     SEYQESFSLPDSSISRFTSLLSEALRNEYIVRKGELSLRAISKYINLRMSILNKNYIN
                     CKQNPIFRSNILGDIYFNVKDYKSYIKKKVFQEHDDYIIYNVKSLHISIIKRYSVEVI
                     LKNKFSYCDISEISKEVFDIVKSVEVYNSEIGEDRLKGKDANIIWVYFGKDEIDMING
                     IYMCKTTWIDKYQEKDIWYSVNGKNKFFINGVHTETYDNYESLKSYISQNTITKEKAV
                     YEVKEILTNMINISEEIISFYNEYENKKICEDNIFQIIDSRKKKMDECYNKVINLDFP
                     PIEIKDWFDKCINLVSTIQNFGVYWDHSRTEENRKQCMEMNIEDYYKDLREVIRLSEE
                     I"
     gene            complement(10807..12237)
                     /gene="dcm"
                     /locus_tag="PC503_002357"
     CDS             complement(10807..12237)
                     /gene="dcm"
                     /locus_tag="PC503_002357"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HDF2528326.1"
                     /translation="MKKITIDKNRVRKIMKEKNIRSQNQLALNMGITKNQLSAILSEK
                     FTPIKSNVEKLCEVLDIGFDEIMCLEDVNEKQLKFTNICSSNKDYIEHRDCTYKELSE
                     YELNPRERNKNNKHIDISNVLAKRAYTCVELFAGAGGLALGLEKAGFKEVGLVEWDKY
                     ACDTLKLNRPDWNVIQGDIVKIAENGIKNYIDNNIEIDLLSGGYPCQAFSYAGKKLGL
                     EDVRGTLFYSYAKILEELKPKVFLAENVRGLVSHDGGKTLKTMIDVFSEIGYNVKYEI
                     LKAVNYGVAQKRERVIIIGTRKDLSHVDFKFPKSFEYVATLRDALKNVPKSEGARYPE
                     RKKKVLDMVPPGGCWIDLPDEVARDYMGKSYYSGGGKRGMARRISWDEPCLTLTCSPA
                     QKQTERCHPDETRPFTTREYARIQSFPDEWEFTGSVSQVYKQIGNAVPVKLGKAIGLS
                     IVDYLNKIEKIYVTEEVAITEEEYVI"
     gene            12450..13166
                     /locus_tag="PC503_002358"
     CDS             12450..13166
                     /locus_tag="PC503_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDF2528327.1"
                     /translation="MTELEKQEILDKAKDFFTNILVANHKKNTIKLNLKAFNINPFLV
                     KYLASFLTGSNKPEDIAKALIYPRVLGTSINTSFGTNLQKFCITTLDGFASTTSGIDI
                     EFIDCIDGRRKFCQIKAGPNTINKDDVKTIIDHFSSVKRLARTNGLSLSYNDLIVGVF
                     YGTENELNAHYKRINEEYPVVVGQDFWYRLTGDENFYFDLIDTIAQSALEEDCTVLLK
                     KTISNLADEISKDKSLFNQK"
     gene            complement(13411..13689)
                     /locus_tag="PC503_002359"
     CDS             complement(13411..13689)
                     /locus_tag="PC503_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528328.1"
                     /translation="MYDEIIEIYFDYWINEHMYRKVLEKDEYYNDRCKEIKKVNKLLE
                     KNLSEEKKMDVLIELNDLFNSVIEIERELGYKLGFKAGARFMIELLNS"
     gene            complement(13937..15271)
                     /locus_tag="PC503_002360"
     CDS             complement(13937..15271)
                     /locus_tag="PC503_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528329.1"
                     /translation="MDNMSNLVKNTEAEQSILGSILLDSRKIEEIEILISEDMFYHQE
                     HKHIFNSVKDIHKRDEPIDIITLTEDLKKKGLIDYVGGISYLTKLSTIVPTIGNVSHY
                     IEIVIEKYKNRNIIDKFNKFKLGEIDDNTLIYQLEKYVNEVNQKLVKKDSSITAISER
                     AFEYINDEIEEGIDIGIKFLDETIGGLYSGELITIAAKSGRGKTALALQIMRNVVFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNEEEIIKYINALSTLNQENNLY
                     INDSVNTISGIKREIKSIKPDVVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPIIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALDYCKTMGIE
                     DIKELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGSLFSFKECKKVKEV"
     gene            complement(15284..16027)
                     /locus_tag="PC503_002361"
     CDS             complement(15284..16027)
                     /locus_tag="PC503_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528330.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNVNNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKANFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDAEAYSPDDSQLKW"
     gene            complement(16048..16362)
                     /locus_tag="PC503_002362"
     CDS             complement(16048..16362)
                     /locus_tag="PC503_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528331.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKEKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDNWFIENANGI
                     KL"
     gene            complement(16366..16560)
                     /locus_tag="PC503_002363"
     CDS             complement(16366..16560)
                     /locus_tag="PC503_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528332.1"
                     /translation="MKLKLKRIEKGIKQYELAEKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKEE"
     gene            16844..17560
                     /locus_tag="PC503_002364"
     CDS             16844..17560
                     /locus_tag="PC503_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528333.1"
                     /translation="MIKKISTALSIPINRLIIDESDLDTSTNNYTNLKELDLVVKTFD
                     NYSAKLIGNNISKFRNINNISLKELSEKINCSENEIINYENGTKMPRIEILKKIALAT
                     YTKIEDLFGFPLEEIKIDNQTILYRNPQTGYIIDNFLIDFINKDINIDNTPVSYYIDK
                     SEFDLVIHILKNYGYDVKTDYKTKFEIADNADTIKPISLSFSDFKDFSKNLNWVINGL
                     VENFIQENSNGLIEDEDEEY"
     gene            17657..18409
                     /locus_tag="PC503_002365"
     CDS             17657..18409
                     /locus_tag="PC503_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2528334.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVSDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            18399..19565
                     /locus_tag="PC503_002366"
     CDS             18399..19565
                     /locus_tag="PC503_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2528335.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNSDILKAGELYRNDNYVFCNELGAPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKIEAVEKLDKIFSL"
     gene            complement(19682..19912)
                     /locus_tag="PC503_002367"
     CDS             complement(19682..19912)
                     /locus_tag="PC503_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528336.1"
                     /translation="MEANKTLLQSLYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGISDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(20161..24732)
                     /locus_tag="PC503_002368"
     CDS             complement(20161..24732)
                     /locus_tag="PC503_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007062489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2528337.1"
                     /translation="MTFEEIMEFNKPYNQKNFDELVNAIKDGYVVPYIGAGMSMLFKD
                     IYPSWSTFLNNTSEEYLEDEDKILFEKIEDYEKKAEFLYEELAKVRFSKHLKKVFGAG
                     YLDAKDKDDFIDKCVYLIPIIFGSGLIITTNYDKVLEKNYGLHNKTVLVSHPGHFEAL
                     NNALRNNELVLYKIHGDITEPTTSIVLTKEQYEKAYSNDELRKMLTQVYTSKELLFLG
                     CSLEKDRPLELLQQVSEAGTGHYAIIPVSSEKKKHRRIELENEYYIQTIMYPEGKHEC
                     VRIILERILEIVLPDEYRRLKDRSLKESRLTNLSCRLTEKWFQNQNNIQIKNLGDRYL
                     PELNVELSLENTFNALGKNEEFKQRFDEKTDKVLSSIKKQKINEVEVDVLVIEEIIQQ
                     FYDKANERLDIKLLKKHFEKISAALDDRINNFKNIIINEDCEKSKKREDEIYKLKQTQ
                     KDIYVYIKYLDSKEIKVVNSPYILLHSAGGMGKSHIIAHTIEKRNMDGHKSILFLGQH
                     FKLDKTPIKHMLEILEIECEFEELLEILNEIGEKEQQRVILFIDALNEGQGKELWKYY
                     LNGIVEQIKKYPWIGLILSIRSEYIPSLIDNNNKIKENLVFIEHQGFSSIEHKAMKKY
                     FDYYGIPYSNIPMPNQEFRNPLFLRIMCETFKGEEINLDTISFTDIYKNYLNILNLRI
                     SESCNYSRHANVVTEVLNEMIKYKYGDGLGNNLIPANKSVEIIINIASKYKINNVIID
                     ELIANGIVNKTVNLNDEEYMHVTYEKLEDYLYANLLVKELKEIGVVDFSHKYKYLVEY
                     EDILEVLAIVLSEETGSDIPNEIFEVFKNKETNYNVISAFINALKWRKKSTITEKTLD
                     YINKIVLGKSYYKIDFYNVLILISTKVNHTLNADYIVKYILQNTMADRDAIFIPIFNE
                     VYEEEESSIKRLLGWCFDFEGFDNTSNETIRLSAMMIATFLISSNRDLRDKSTKALVN
                     LLTGKMDIVIDLLKTFEDVDDPYIIERLYAVAFGCVVSEQSEEMIEALAVYVYNKIFD
                     VDYVYPNILLRDYAKNIVDYAKYKIDSSVLKDMNVEPPYKSIFPKVPTDEEIEGYKYD
                     YKASDFKDYYWSQNTILNSMEVEYTRDGQPGWYGDFGRYMFQHYFHKWKGLDYNDLKN
                     IAIKKVFDMGYDVNKHGKFDRTVQNGRLRDSKYERIGKKYQWIALYELAAQAADNYKI
                     EVYTDAYGTKKEIYCKGTFEPDIRNIDPTVMTVINNNNNKRVHNQLFQFSPIPNNEWL
                     GDFSDLPSINDMVNSVYKNQDFLLLNGWYTWKEENDFKNKNYKNPEKDMWVLINSYII
                     KNDQLEPIVNALKGKDFMGRWLTEPNSNYTLYNKEYYWADGYYFFQNSYYCGEEWVQI
                     DEHKNILEKDYKVLLPTYSYTTEREGDIFQEDFSGTWHKPCSTLFYGLKLRYGQGDSI
                     LYNDYGEVVCFESSELLNEEIGFFINKEIFLKYLNEQGYSVFWTMLAEKRVLEEPYMD
                     RKYIQPTISGVYTLNGENRLVGETIESEY"
     gene            complement(25137..26051)
                     /locus_tag="PC503_002369"
     CDS             complement(25137..26051)
                     /locus_tag="PC503_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HDF2528338.1"
                     /translation="MELVKNIHKNKSKDEIFKELLENLKGTIASWDYYVNWNKALENT
                     RKIEVQLNILNYLIGKEDIENETKNLLKEYPEVLSVIPIVIASRDNEFKILDPSDEDM
                     FKYKLFNFKKRKSISDEESELATEFLKKIKFLDLLKQKNIKNLVDYVFGVEVGLDTNA
                     RKNRTGSSMETLVERYVKNMCEKNNWSYLTQATVKKISEKWSIEVPTDKSKRKYDFAI
                     NNNGKIVLVEVNFYNGGGSKLKSVANEFTKLDKYIKDGGFTFCWITDGLGWLESSIPL
                     RDAFDKMDYIFNLDMVDKGSLEYIIKNL"
     gene            complement(26070..26984)
                     /locus_tag="PC503_002370"
                     /pseudo
     CDS             complement(26070..26984)
                     /locus_tag="PC503_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008909111.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
     gene            complement(27412..27761)
                     /gene="ssrA"
                     /locus_tag="PC503_002371"
     tmRNA           complement(27412..27761)
                     /gene="ssrA"
                     /locus_tag="PC503_002371"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(27919..28374)
                     /gene="smpB"
                     /locus_tag="PC503_002372"
     CDS             complement(27919..28374)
                     /gene="smpB"
                     /locus_tag="PC503_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF2528339.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            29001..29828
                     /locus_tag="PC503_002373"
     CDS             29001..29828
                     /locus_tag="PC503_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2528340.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            30853..31317
                     /locus_tag="PC503_002374"
     CDS             30853..31317
                     /locus_tag="PC503_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2528341.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(31584..32228)
                     /locus_tag="PC503_002375"
     CDS             complement(31584..32228)
                     /locus_tag="PC503_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528342.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMVPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(32158..33447)
                     /locus_tag="PC503_002376"
     CDS             complement(32158..33447)
                     /locus_tag="PC503_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528343.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(33444..34316)
                     /locus_tag="PC503_002377"
     CDS             complement(33444..34316)
                     /locus_tag="PC503_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528344.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT        11753 a         5369 c         3580 g        13808 t
ORIGIN      
        1 taattaattg aaaaaactag taaaaatatt aataaatatt atttgcatta ttacgctaat
       61 tttctctagc ctttcgattt acataaaatt atctgaatat aaaaaagctg atgaagtata
      121 tacggaactc agagaaaaca ctatcaataa tagcaaacat caagaacttt atgataaaaa
      181 taatgattat agattctggc ttaaaataaa caacgtaaat atagactatc ctgtagtaca
      241 aggatataac aatgatttct acctaactca tgatttttat aaaaattatc ttcctttagg
      301 tagtattttc atggattata gaaataattt tgaaaatgat aagagtttaa tagtctatgg
      361 tcattatatg aaaaataaaa ctatgtttgg tcagctagaa aactatactg atgaagcatt
      421 tttcaaagaa aataacttag tagaaataaa ttataaagta caaacttata cttatgaaat
      481 tttttcagta tatactgctg acttaattaa cagagattat ttaagtatac actttaatag
      541 taattatgag tttaaagatt atttgaatta tataacctaa aaatcagtac acaaatctga
      601 tataaaggta gatatttcag ataaaattat aactttgtat acttgtaact atgaatttaa
      661 agatgctcgt actatagttc atgctaaatt aatttcaaaa aaagagactg ataagtaggt
      721 ttgtgtaaat gcagacttac ctacagtctt ttttgaacgt aaaattagta agtatggaat
      781 aatattcata ttaaactttt gtaggcaaag aaatgaaaaa tcaaagagaa ataattatta
      841 cagatttaga ttaccaagct gaattaagaa agtgtaaaac tatggaggat gtagttggtg
      901 aagatagtat ataatagttt aacttataaa ttatcttggt gatattaatg aagtttcaaa
      961 gtatatatta tttattgata taaataatat taaatctgtt gctaacagat gtacctttgt
     1021 ttggagacaa actatttaag aaatataact aaaatgttga agtagctacc tgactttatt
     1081 ttgaaatgcg aacaagattt tggcattaag ataatttaga aagaatcact ggtacacaag
     1141 gatgtgaact tagaatgaat agaagtattc aggcataagg agctttcacc caaataaaac
     1201 atagtatgaa ctttaaaaga attctaatca gaggcaatca aaatgttctt tcatagttta
     1261 tacctgtagt gttagacata gtatttataa gtttcacaaa taagataatc attaataaat
     1321 gtagtatgta tattcatcct ctcaaaaata ttttttaatc ttacactttg taaattattc
     1381 tattttaaaa tggtattttt atacctttat ttcttatgac cgttttcaag ctcaaatttt
     1441 gcataaatat aaattaatga aaagcaagta aaaaaagaac tgtcgcacag caatttaaaa
     1501 ttactcattc gacagtcctt atttcgtgga tttaaatagt ggagaagaat cacaagaata
     1561 atacccacga ttaaaccttt atacaataca ttttatatga ctttaccatc actaatagtt
     1621 attatacaat cagccatctt agctatttca tcattatgag ttatcataac caacgtctgc
     1681 ttgtattcat ttacacaata ctttagtaaa ttcatcacct cattagttgt tttactgtct
     1741 aaatttccag taggttcatc tgcaaaaatt attgatggct tattggcaag tgatcttgct
     1801 attgcaactc tttgttgttg accacctgat aattcattag gaaatttatt aatctgactt
     1861 tctaatccta acttagttat taaatcatta atataattat tatctatctt tcctttagca
     1921 attaaaatag gaagaactat attatcataa acattgataa caggtattag attatagttt
     1981 tggaatataa acccaaattc tttacttcta agattagata gcttttcatc acttaaagta
     2041 tataaatcta aattatccat aaatacatta cctaaagttg gtttatcaag ccctgccata
     2101 cagtgaagta atgtgctttt tccagaacca ctttgtccaa ttattgcact aaatttatgg
     2161 ggttctatct ctaaagtaat tccatcaaca gcctttattt cattttctcc ttttccatat
     2221 atttttttaa tatctataac ttttaacatc ttcatacatt tacctcccaa attattcatt
     2281 ctcttttata ccttcaataa tattcatact ttcaaaatct ctattactta caactactga
     2341 tattaaacat acaaatacag atatagcaaa gaatagtaaa gattccttaa ttgggaatgt
     2401 aaaagacata aaattctcta ttccatagtt tatatacgca tcattattcc aatttgtaaa
     2461 tttaactaga tttataaatg atggaatcat agctattata aagctaaaaa ctgcatatgc
     2521 taatgcttca tatataagca tttttttcat atttttaaga ctaacaccta atgctctaag
     2581 cgttgaaatt tctttttttc taattagtag atttgttctt atagtacaga aaatattaat
     2641 tgatgctatt attaaaacta gtgcaattat tgctatttgt gatttaatgt aacttttata
     2701 tatactttct gacatttcat gataacttaa tctactatta aatagagacc ctggtatact
     2761 tcttgaaatt ttctgtatct cattattaac aatctcatca tatggatttt ctaaatttat
     2821 gcctaattga gtgtattttt gttctcctgt tatgttttta gagtgaatat tacttgttat
     2881 aatttctaga tctggcataa aatcgccatc tcccatagca atccattcat cctttaaaat
     2941 tacagccact cttaccttca tctctttata aacaattgta ttattttctt caacaggaat
     3001 ttttacagtt attatgtctc ctatatttaa ttctttgaat ataggcttta tagtatgatc
     3061 atcaactata tcataaaaat aattatatac tgctacattt ggatatccat cagtgtcctt
     3121 tttaatatca tctaagctac cttcttcaac aaagtcattt aacttttcat ctatataatc
     3181 atcatcataa agctttaaaa ctaatttatc ttccattatc tctttttttt ctactccatt
     3241 ataggttgta aattctttgt ttatatcctt attattaaaa gtaaacattc catttgttat
     3301 ttgaatttta tgtatacttt taacaccctt aattttttct atattctcta catcactatc
     3361 tgtgtatttt gatatttgcg ggtctgcatt tactccaaat tgcattgtta tattatatct
     3421 attttgcata tcttcaattt tactgttgac ctcttcttgc atacttgaga atgtagtaat
     3481 gaatatatat cctcctaaag caatagacaa catagatata gcagctctaa ccttatttct
     3541 tccgatattt ttaagtccca taaatccata aaatccaaat attttgctta ctagtctgtc
     3601 tattccaagt ctacttctgt gatttttaat tttgtctgta tttattattg attcaatagg
     3661 tgatatcttg ccgattttaa aagttggtat aatacaagat ataaaaacag aaatcattcc
     3721 aaccaatata gcttttataa ctatttcatt atttatatat aatttagggt taagaccagc
     3781 ttcactgtat aaaacttcgt tataattact aattcctata tatgaatatg taaccccagc
     3841 tactaaccca agtagtatac ctattattgt tataattaat gcttgataga ttatcataca
     3901 ccttatgttt cttttctttg cgcccatcag tctaagcagt cccatttctt ttactgattg
     3961 atttagtgta atattgaaaa tattaaatat gaaaattata gatactgtag ttattaaaac
     4021 atttctttta aaaacattcg gatcattctt atcatcttct acataacgaa gttcccttac
     4081 aagaggtaca tttggtagaa aacttttttg tcccaactta tattttttca taagataatc
     4141 acattcacct tcaatatttc tccatccact tttaaaactt aatatactat tataactaat
     4201 cgcatcatga ggtataatgt tatttgtttc atcattgcca taagttactg cttcgtattg
     4261 ccaaaccaca tcatagtacc cttttggttt ttccataact cctactattt taaattcttt
     4321 atttatagaa aataattgat tacttccgtt agtatcttta tagttctttt ttattgttaa
     4381 atttaatgta gatcctactc cttcacttaa attcattgct tctagtgctt ttttctctaa
     4441 tactatttca ttgttgtttt taggtagtct accttctatt attttgttgt atctactttt
     4501 tagatactct tcgtttgatg aagttaatat aaatgagttt ccttttttat ctgaaatacg
     4561 tcctagattt tgtaccgaat taccctttga tactttttca tcagtttcta attttttagc
     4621 atcatcaagt gtcaaatcac taaactctac atggtatcca ctgtaaagtt catgtattgc
     4681 tactacattg ttttcatttt gtgaatcttt tataacacta ggtccaaata tcaacataac
     4741 acctaacata actcctatta ttaaaagtaa tgttctaagt ttatttttct ttaaatatgc
     4801 tagtgacatt tttaagtaaa tccccatata atcctcctat tttactataa attatttatc
     4861 caactcatct gttaagtaga ttggtggata ttttaaatct tttaattctt cattattttt
     4921 tgaagcttac taccatcttc ctcatgataa acttgcagta tcaccttatt tacatgtagt
     4981 gcataataat caccattata aaaatattag tatttataac ctggataatt tttgtaaaat
     5041 gatttataaa gtatcccatc ctaattctat tttgtatact tttcttttgt aatacgctct
     5101 atatcatcac ctgaaactcc ttgatatgtc atatatttat ctatatattt ttcagcttca
     5161 ttccattttc taaaatagtt gttgtatata ataaatccta ttatggctat aatgcttata
     5221 attaaagtta ataaaatagc tttgtatttt ctcatagtga atcttcctac ttcaatttaa
     5281 attctttaat aagttttaat tctaaagact tagttttatc atcaaatttc ttaacttgaa
     5341 tttttatatc tcccaaatta tcaacctcta catttacttc acctttatca aatacttctt
     5401 caatttttct aaaaaattct ttctcactta tttctatatg aatcaatgat ctatatgtta
     5461 taaatggcca ttatgaattt atcatcttct gacagctttt cattataaga aaaatcttta
     5521 acacattgaa ttgataatat ttccttcgta tccttctttt ccttagttat tgaataatgt
     5581 aaaacttggc taggttgttc ttttgtatac tccaagtttc ccaaagacaa aacaaaactt
     5641 ccatctgatt tattttcagc taccctaaga ccactatttt ctattgattc tgatattttc
     5701 tttgacaagt cttcttgata ctagaaatct gttcaatagt atatattttt tcatttgtac
     5761 ctgaaacctt atttgtgcat cctgttatta aacctagtgt taagcttata gctataacca
     5821 tagttattgt aattttttta tcttcatata atcctcctta tatattgaaa actcgttatt
     5881 tctcataaaa aaaagacgct atctttttct attaaaagat aacatcccta tatgtttagt
     5941 atcaatatat gttccccaac tggtaggtta atcgacccaa ctatcaaaat tttgatttaa
     6001 tggtatataa atattcaata taaatttgtc ttttttatct tcaaatgata aatctcctct
     6061 atattttttt atagaagatt tgatgcttta aatccctatt ccatgtacaa gtttatcttt
     6121 tttatctgtt aataataaac ttttattctt tctaattgaa tttattttac tattctcaca
     6181 tttaattacg aaataggact ttgagatagt tccttttatt tgtatatatt tatcaatact
     6241 tttatcatgt atcttatcgc aagcttctat tgcattatct aagtatttgc aaatatatta
     6301 gatacatcta ttggttttat aaaattcact ttggaaaaat tgatatcaca aatgaattta
     6361 atttttcttt tttcacttac atcacttttt tcatttatta ttatatccaa tataacatta
     6421 cctgtattgt aaattgattt aaattcttta atttaatctt ttaaactatt tacataccca
     6481 tcaattttcc ttttttatat ttgagatttt ctatacaata tatatgatta tttatatcat
     6541 gataaagctt cttaacttta gcgtgtgatt cttgaatact tagataatga gaatactgca
     6601 tatctaactt attttttatt acttcatttt gcaattttaa cttattttcc ttaattattt
     6661 ttataaacac tataataatg actaagctac tagctagtat taacctaggt atcacaatat
     6721 acccaactat atatatttcc taatacccac caaatcgata catttttcta tttatataaa
     6781 ttattaatat agtaaataaa tttgttatta aagcaacaga taagtatata tagtttattt
     6841 tattatcttt atctagtccc aatcttttat taataaattt aaatatagca caagctacta
     6901 tataactatt attataagat aatagtatat atctacttta gcattatcat aactaaacac
     6961 taatagagct tcctctgatg atattacatt acttgtaact acaaaaaata aatttataga
     7021 tataacatct tttattaaag ggtgatatac gtcaaataag aaaaatgaaa ctatatattt
     7081 aacaattcct atcttataaa aataattata gtaagttccc aagtaataaa tatcaaataa
     7141 tagattatat catatagatt tttcttcata ttataatcat gggtcttatc aacattaaat
     7201 aatataatga tcttagttat aagataagct aataatacag taaaaaaaga tattttctta
     7261 gtcttatctg tatctttatc gtaagttaat atacttttta gtatcattat tggtgtaaac
     7321 aatgataata ttaataatat tttatttata tggtttaaca tattctatca ccaataaatt
     7381 ttagaaaccc ctcttttata tctttatatc tatatctact aataggtact tcttcttgac
     7441 tgtctaatat tgcagtattt gactttatat tttctacata gtttaagtta gttatataac
     7501 ttttatgaca tcttacaagt tcctctatat ttaaatcttt ttctattttt tctaggatac
     7561 atatagcatc aagagtttta ttttttgtat gtattagcat gttctttttt tgaacttcta
     7621 tatatttttt tgctagatta gattttgtat gtgttagatt tatttttatt tttttcaatt
     7681 tttttggtac atgttaatat gtgtttttct agttcttgaa aatttattgg ctttaataag
     7741 tatcaataag ctcttacttc atatctttcc tgtacataat ttattagaga tgttataaat
     7801 attattatct acttttctta tgtttcttgc gatatctata ctatttagtt ctgccatttt
     7861 tatatctaag agtagtgtat cctctcaatt aactttgtaa tgattcttct tttgagctat
     7921 atttttttaa ttcgatattc tttgttttta ttttttaata tattatcaac ttgatttttt
     7981 attacgattt gtatttcttt ttcatcatca caagctgtta ttgtaatgat aacctctcct
     8041 aatattgtat ttttatttag attcttcact ttaggttaaa actttttaaa tgtatttatc
     8101 aataatattt aaattaaaaa tgtataaaaa tacctatatc caattggata taggtattcg
     8161 tggatttcaa tggtggagac gaggggagtc tataagtggt tatttgattg ttttgttgtt
     8221 ttttgcaagt gtaggtatat agctatttag ttatgatgtt aaactgattt tttcggatat
     8281 tttttattgt ttatttttgt agttggggta ttattggggg gggggtggat gatataatct
     8341 tttaatttta taaaagttcc attaacagca tattatacgt ttttaaatat ttactagact
     8401 ttttcaaaat aaatatctaa ttatttaaat caataccaat ataatttata aatggattta
     8461 taattgtatc ttctatcatg tttagtgtaa acaacttatt ttaatttaaa ttcgtaacca
     8521 acaaagtacc aatctgactt ataattctat attagtacaa ctatggaaaa atttaattct
     8581 atatctcctc acttaatctt atgacttctc ttaaatcttt gtaataatcc tctatattca
     8641 tttccataca ttgctttcta ttttcctcag ttctactatg atcccaataa actccaaaat
     8701 tttgtatagt tgacactaag tttatacatt tatcaaacca atctttaatt tcaattggtg
     8761 gaaaatctaa atttataact ttattgtaac actcatccat ttttttcttt ctactatcta
     8821 taatttgaaa aatattatct tcacatattt tcttattttc atattcatta tagaaggata
     8881 taatttcttc agatatgttt atcatatttg ttaaaatttc tttaacttcg tatactgcct
     8941 tttctttagt gattgtattt tgacttatat atgattttaa gctttcgtag ttatcatatg
     9001 tttcagtgtg aacaccgttg ataaaaaatt tatttttccc atttacacta taccatatat
     9061 ctttctcttg atatttatca atccaagtag ttttacacat atatattcca tttatcatat
     9121 caatttcatc tttgccaaaa tatacccata ttatattagc atcttttcct tttaatctat
     9181 cttctcctat ttcactatta taaacttcaa cagacttaac tatgtcaaaa acctccttag
     9241 atatttctga tatatcacaa taggagaatt tattttttaa tataacttct actgaatatc
     9301 tttttattat acttatatgt aaagatttga cattgtatat tatgtaatcg tcatgctctt
     9361 gaaaaacttt cttttttata taagatttat aatcttttac attaaaatat atatctccca
     9421 gtatgttaga cctaaagata ggattttgtt tacagtttat ataatttttg ttcaatatac
     9481 tcatacgcaa attaatatac ttgcttattg ctcttaaaga taactcccct tttcttacta
     9541 tgtattcatt tcttaacgct tctgataata aacttgtaaa tctactaatt gaactatctg
     9601 gaagagaaaa tgattcttga tattcgctac ttgatactaa cactgcacat ccttttctat
     9661 caaacaagga aaatatgtct ttaatattta ttttttgttt gtcacttaca ttaaatttac
     9721 ctgcaaagca acaatcaata aatacaattt tatttttaca atttaatcct tctataaaat
     9781 caattacaaa ttgaatagaa actaattcat cacttaatac taagtaatgc actccgttat
     9841 tacatatgca tccatgccct gaaaagtaaa atataaatgt atcatcatct cctatagaat
     9901 cgcttatttc ttgaaaagtt ttaaaaaata aatcttttct gacttcatac tccataccta
     9961 aagttcttat attattcgaa gtaatcccca gtcttttatg taacacatta ttaatttcaa
    10021 ttatatcatt tttacaaaat agtaaatctt tatttttaac tatactatat ttacttactc
    10081 ctacaattaa tgcttttaag cttttcatat tccattcccc ctttataatt tttcaattta
    10141 atatacttaa aatgatgttt taattgtttt attgatttta taaaagctag tatcacacta
    10201 cttttttgac tttttcatta tttacttttg tagttggatt ataatttttc aaggtaagta
    10261 tatatatatt tatttacatc gcacccatat aatttatatc tctgatttat ctgacctgaa
    10321 cttagtgtaa tttaaaccaa tgtaaaatca tctatctctt caccatatat tttttaaaat
    10381 tccccaaaat attgatgtta atagaatttc atgtgttttt tgtattctac tatccataag
    10441 aattttaaag tgagtaaata tttccaatca tttatatctt atttaatatc attttattcc
    10501 ctcaagtatt tatttaaatt gttatgcttt atttataaaa ttatacatac atttctaaag
    10561 ttagacatac atctttaaaa acctttaatt tgtgctactt tttttctaaa aataataaat
    10621 atataaaaat tatatataca aaaaattaag ttatgactag tttataaata agtacataat
    10681 aaaattaaag agagcaattt tttttgctct ctttcaaaat ttatattaaa ttgtaataat
    10741 aaaaataaaa acgctagtta tctaaggcta atattttcaa cgattatata aatatctaca
    10801 taacagttaa attacatact cttcttcagt tattgcaact tcctcagtga catatatttt
    10861 ttctatttta ttaagataat ctactatact taatccaata gcctttccta gcttaacagg
    10921 aactgcattt cctatctgct tgtacacctg actaactgac cctgtaaact cccactcatc
    10981 aggaaaactt tgaattctag catactctct agttgtgaat ggtctagtct catctggatg
    11041 acacctttca gtttgctttt gtgcaggact acatgttaaa gttaggcatg gttcatccca
    11101 acttattcgc cttgccatac ctctttttcc gccaccgcta taataacttt ttcccatata
    11161 atctcttgcc acctcatctg gcaaatctat ccaacaccca cctggtggta ccatatctaa
    11221 cacttttttc ttcctctcag gatatctagc tccttccgat tttggaacat ttttaagtgc
    11281 atctcttaac gtagcaacat attcaaacga cttagggaac ttaaaatcca catgtgacaa
    11341 atcttttctt gttcctatta taataactct ttccctcttt tgtgcaactc catagttcac
    11401 agcctttagt atctcatatt ttacattgta tccaatctcg ctaaatacat ctatcatagt
    11461 ctttaatgtt tttccaccat catgagatac aagacctcta acattctctg ctaaaaacac
    11521 cttaggcttt aactcttcta gaattttagc atatgaataa aacaatgtcc ctcttacatc
    11581 ctctaaccct agcttcttac ccgcatagct aaatgcttgg catggataac cacctgatag
    11641 caaatctatc tctatattat tatcaatata attctttatt ccattttccg ctattttaac
    11701 aatgtcaccc tgtataacat tccagtctgg tctatttaat tttaatgtat cacaagcata
    11761 tttatcccat tctactaatc caacctcttt aaaaccagct ttttcaaggc ctaatgctaa
    11821 tcctcctgct cctgcaaata attcaacaca tgtatatgct cttttagcta gtacattact
    11881 tatatctata tgtttattat ttttatttct ctctctagga tttaattcat attcactgag
    11941 ttctttatat gtacagtctc tatgctctat ataatcttta ttactgctac aaatatttgt
    12001 aaatttcagt tgcttttcat ttacatcttc caaacacata atttcatcga atccaatatc
    12061 taacacttca cataattttt ctacattact ttttataggt gtaaattttt ctgataatat
    12121 tgcagataac tgattcttag ttatgcccat atttaatgcc agttgattct gacttcttat
    12181 atttttctct ttcataattt ttctcactct atttttatca atagttattt ttttcattta
    12241 gttcacctct taataaataa tataccctta aatagttaat aaaatacatt aactatttaa
    12301 ggatatatta tcataattct aatttttatg taagtagtta taaaaactta aaataaaata
    12361 tctgtaaaca acctaatatt acctcataat tttacacatt atggaatata ttgtataatt
    12421 acattaatac tttttagggg gattatttta tgactgaatt agaaaaacaa gaaatactag
    12481 ataaagccaa agattttttt acaaatattt tggttgctaa tcataaaaag aatactatta
    12541 agttaaattt aaaggcattt aatataaatc cttttttagt taaatactta gctagtttct
    12601 taacaggatc aaataaacct gaagatattg ctaaagcatt gatttatcca agagttctag
    12661 gcacttcgat taatacgtcc ttcggaacta atttacaaaa attctgtatt accactttag
    12721 atggttttgc ctctacaact tctggcattg atatagagtt tattgattgt attgatggta
    12781 gaaggaaatt ctgtcaaatt aaagctggac caaacactat taataaagac gatgttaaaa
    12841 ctataattga ccactttagc tcagttaaaa gacttgctag aacaaatgga ctttcattat
    12901 cttataatga cttaattgtt ggtgtttttt atggaacaga aaatgagctt aatgctcact
    12961 ataaaagaat taatgaagag tatccagtag ttgttggtca agatttttgg tataggctta
    13021 ctggtgatga aaatttttat tttgatttaa tagatacaat tgctcaatct gctttagaag
    13081 aggactgtac tgttttactt aaaaaaacaa tatccaatct agctgatgaa atttctaaag
    13141 ataaatcttt attcaatcaa aagtaatata aaaatgatta aatagcataa tttacatttt
    13201 tagatattta aaaataatat tcaccaaaca aaattattaa gtaaaatgaa atgtatctta
    13261 taaaagctga gctataagta aatctttgta aaaacaaatt tacttatagc ttttttatgt
    13321 tcaaaaaaca caaattatat actatttaat atattataaa cttttatttg ttaatactct
    13381 ctactaaatt tctaacatct cttatataaa ttaactattt aataattcaa tcataaatct
    13441 agctcctgcc ttaaaaccaa gcttataacc aagctctctt tcaatctcta taactgaatt
    13501 aaataaatca tttaactcta tcaatacatc cattttcttt tcttctgata aatttttttc
    13561 tagtaattta ttaactttct taatttcttt acatctatca ttataatact catctttttc
    13621 tagtactttc ctatacatgt gttcatttat ccaataatca aaatatattt ctataatttc
    13681 atcatacatg ttagtacctc cttgactttc atctggtact taatatatac ttaacttgtg
    13741 tagattagtg tacattaagt acctaattta taaaggtagt tgttatattt atatggcaac
    13801 tacctttttc taataaattt ttcaatctaa atactatata ttttaaatct tcattgctta
    13861 ctattgagga ttatatactt ttcttctaac actccttaaa caatagttta tatatcactt
    13921 aataaattat attttttcat acctccttta ccttcttaca ttccttaaaa gaaaacaaac
    13981 ttcctatata ccaataaggt ctaaagcctg attccccatc tctattttta gcaactataa
    14041 tttcacttaa attagctcca aaaccttttt ctctacgtct taattctttt atatcctcta
    14101 ttcccattgt cttacaataa tcaagagcct ctttctctgt aggtctatga atatatatga
    14161 ctgaattaga atccatatat atctgttttg aacttctcat tactctatct ccttttggcc
    14221 tttcatcctt caattcatca tttaattgag ccaactgtat aattggaata ttaaagtcta
    14281 aagtaatctt ttttatttgc cttgataaat cagcaaactt agcttctcca acttctttac
    14341 cttcgtaatc caaaatctga agataatcaa ttataacaac atctggttta atacttttta
    14401 tttctctctt aattcctgat attgtattga ctgaatcatt aatatagaga ttattttcct
    14461 gatttaaagt acttaaagca tttatgtatt taattatttc ttcttcattt agatttctat
    14521 tcttcatttt tacaactgat attccagtta aagaagctat gtttctaaac aaaatttgta
    14581 tatcactcat ttccccactt ataaaaagta cttttttacc ttgaaatacc acatttctca
    14641 ttatctgtaa ggctagtgct gtttttcctc ttccactttt ggctgctatt gtaattaatt
    14701 caccactata tagacctcca atagtttcat ctaaaaattt tattcctata tcgatacctt
    14761 cttcaatttc atcatttatg tattcaaagg ctctttctga tatagctgtt atactagaat
    14821 ccttcttaac caatttctga ttaacttcat taacgtattt ttctaattga tatataagtg
    14881 tattatcatc tatttcacct aatttgaatt tattaaattt atcaattata tttctatttt
    14941 tatatttttc aataactatc tcaatataat gggatacatt acctatagtt ggaactattg
    15001 ttgatagttt tgtcaaataa cttatacctc caacataatc tataagcccc tttttcttta
    15061 aatcttctgt aagagttatt atatctatag gctcatccct tttatgtata tctttcactg
    15121 aattgaatat atgtttgtgc tcttgatgat aaaacatatc ttcacttatt aatatctcaa
    15181 tctcttctat tttcctagaa tctagtaaaa tactacctaa tatagattgt tctgcttctg
    15241 tgttcttaac taaattactc atattatcca taatataaac tccctaccac tttaattgtg
    15301 aatcatctgg actatatgct tctgcatcta ctttgacatt aattgattta tcttgataat
    15361 tgccttctaa tatcttaata aaattatttg ggctcattat ccaatcaaaa tttgccttcc
    15421 aacctttttc attgcttcca tttaaaaagc tagttttact aactatatga ataatttcta
    15481 atacagtctc tttatcatat tcttttattc tagcattaat tacttttttt ctagcttctg
    15541 taagtttctt tacttttgat agttctgtac aagtaatatt gaatttttct ataatttcac
    15601 tgtatatttt acttttttca ttatttacat tcttgttagt tgttagttgc ttgttaattg
    15661 catgttgatt agtctgttga ttttcttcat tagattgata tagctcccag ttttcaatag
    15721 ttataagcct atttttgttt gttgatttat ttgttagaaa tccatatctt tcaaatttct
    15781 ttaaagcagt tcttacattc tgaatactta catcttttga acacatattt gctatacttt
    15841 ccaaagatgt tattaactgt cctgatttaa cttcatattc tttacctcca taaacccatt
    15901 tattaggctt atgattaact gacagtaata ggtttatgag tatatctctt tgtttggaat
    15961 tacaatcttt atatagtggg ctttctttta tctttctatg aagctttatc caacctagat
    16021 tactcaaata ctatcaccca cttaagtcta taattttata ccatttgcat tttcaataaa
    16081 ccaattatct agtttatttt ttattatata cactctatta tctatccata tacaaggaaa
    16141 tcctttattt ttagaatgac ataactgtct aaattttgat tcccctatgg gataaatttt
    16201 agaagcttct ttacaagtga taagttgagc tttatctctt ctatatgtct gtatctcctt
    16261 gtaccctttt tccttttctt gtgcttcttg ttcttgcttg acaagtatat tcaatgtagc
    16321 ttgtagtgtt ttaagaactt ctagattatt tgtatctgcc atacatcatt cctccttatc
    16381 aaaaaataat tcttctacac ttgtatctag ttcttgagcc aattttaaca tcaacatatt
    16441 acttggattt tttgatttac ctctttctaa agaagataaa taatatcttg agatgccaac
    16501 tttttcagct aattcatatt gctttatacc tttttcaatt ctttttaatt tgagtttcat
    16561 tgatttcctc ctttctttca tacccatttt gtgtatcctc atttctataa aatattctaa
    16621 cacccatttg gtgtattgtc aatatattta agtgtatcaa tagacccatt tagtgttata
    16681 atgtatttga ggtgaaatta tgatagataa tacaattgga aaaaagatta aacaatatag
    16741 aaaatctata aatatgtcaa gggatgagtt agctaataag attggttgct cagtttatgc
    16801 tgtagctaaa tatgagcaag gccaaagaaa gcctagttta gatatgataa aaaaaatatc
    16861 tactgcatta tcaattccta taaataggct tattattgat gaaagtgatt tagatacttc
    16921 aacaaataat tatactaatt taaaagaatt ggatttagtt gtaaaaacat ttgataatta
    16981 ctcagcaaaa ctcatcggaa ataatataag caaatttaga aatataaata atatatctct
    17041 caaagaactc tcagaaaaaa taaattgttc tgagaatgaa attataaatt atgagaatgg
    17101 aacaaaaatg cctagaattg aaatattaaa aaaaatagca cttgctactt atactaagat
    17161 tgaagactta tttggatttc cattagaaga gataaaaata gataaccaaa caatcctcta
    17221 tagaaatccc cagactggat atattataga taactttctt atcgatttta taaataaaga
    17281 tattaacata gataatactc cagtttctta ttatatagat aagtcagaat ttgatttagt
    17341 aattcatata ttaaaaaatt atggttatga tgtaaaaaca gattataaga caaagtttga
    17401 aattgcagat aatgcagata caataaaacc aattagctta agcttctctg acttcaaaga
    17461 cttctccaaa aatctaaatt gggtgataaa tggtcttgtt gaaaatttta tacaagaaaa
    17521 ctctaatggt cttattgaag atgaggatga agaatattag tattgcacat tttcaaaata
    17581 tgagtttacc tattaacttt tatacattca tagttaataa ataaaaatta gatatgatat
    17641 gaaaggagct aaaatcatga ataaatcata tataccaaaa tacacacata aattccctac
    17701 taatctacct catggagata aaaaatatac tttaacatac attagaagaa tgataagtga
    17761 atttgtatat gatatgggta acctagaaaa taaccccttt acattcccag aagtacaaac
    17821 attacttgat ggtataaccg taggtggaca taaattaagt gaccaaaatc aaatactaaa
    17881 tataaaatca tcatgggatt atgtaataaa attaagtaac aaagaaaact tatctttaaa
    17941 taaagataca atttgctcta tacataaaat agttgcaaaa gatgaagctc taatagttgg
    18001 agattttaga aatggtaaca taggtatagc tggtactact caatatgaat gcatagaagc
    18061 cactctatta aatgatttat ttgtaagcga cataaatatc ataaataaaa taactaaccc
    18121 cttagaaaag gctataataa taaatttatg gttgtcctat tgccaattct tctatgatgg
    18181 caacaaaaga actgctagac ttacctcaaa cctaatactt ataagtaatg atataggagt
    18241 tctatcaata ccagctaaac ataaacaaga atacaacaca ttaatgctaa acttttatga
    18301 aacactagaa gctgatgaag ttataaaatt cttattagag aaatgtatta cattctttga
    18361 tgaatataac tataaatcat ataaggagct gtttaaaaat ggcaactaaa agagctaatg
    18421 gagaaggctc tatcggaaaa tataaagatg gttggcgttc ccgtataatg attggctata
    18481 atgaagatgg taaaccaata agaaaagaat tttatggtaa gactcaaaag gaagttaaag
    18541 ataaacttga tgcttataaa aaacaatatt atttaagctc tgatatttca gatgataaaa
    18601 taactttaga gcattggttt tacaattggt tatttgaata tagaataaaa gatttaaaac
    18661 ctaaatcatt tgaaagatat gaaagcatct atcgtaatta tattaaagat actgatttag
    18721 gcaatgttaa attaaaggac ttaagagtat ctcacataca aaaatattac aatagattgc
    18781 ttgattccaa taaaagtata cctactataa ggcaaataaa cactaaactg aaaacctgct
    18841 tatcagaagc tgaaaaacaa ggtcttatac aacgtaatta ttgtactatg gtaaatatac
    18901 cagttgagaa aaaggagaat aagcttgaaa tattgactct tgaacaacaa aagagtttta
    18961 taaaagctat agatggacat aaattagagg tattattttt acttgctctt ggtactggac
    19021 ttagattagg agaattatta ggacttaaat ggtttgatat tgattttaaa aagtctaatt
    19081 taacagttaa aagaaccctt caaagaacat attttataga taaaaccgga aatagagagc
    19141 ttaaagtatt agagcaagag ccaaagacat caaattctta cagaactgta cctattccaa
    19201 aagatgtttt aaataaattg aaagagcata aagtaaatca aaattcggat atattaaagg
    19261 ctggagaatt atatagaaat gataattatg tattttgcaa tgaattaggt gcccctattg
    19321 atgataaaag acctttaagg aatctaaaat ctatattaaa cagcttagat atagagccta
    19381 taaaatttca tggtcttagg aaaacttatg cgactagact ttttgagaat gatgtccctc
    19441 ctaaaactgt acaagtttta atgggtcatt atgatatatc aataacttta aatatatata
    19501 ctcaagttat ggaagataag aaaattgaag ctgtagaaaa gttggataaa atattttcat
    19561 tgtaaaaatc aaatatataa aaatactctg atttcatata gttaattaca aaaccaaaat
    19621 aaggatacaa attaatttta tattatcttg tatccttatt cttgtctagt tttttaaata
    19681 tttatcttgg atagccttta tgatacatta atccattttc taacattagt tcttgggcta
    19741 aatatatatg acccttacag tgcatatctg atataccctc acttataagt ttatatgttt
    19801 cagaagtata taaataatcc atactttctt ccaagctctt acctgtttgt ttagaaaatt
    19861 ctaatatgat ttttttatat agcgattgta acaatgtctt attagcttcc ataaaagcta
    19921 tacctcctct ttcaaatatt tgtttatcct attttgacta actatatatt tattagttat
    19981 ttaattagcc ataataattc ggctataaga tatttataat ctaatctcaa ttatataaat
    20041 ctttttgcca atatttaata atcaaaatat tgcacttaat taactatctt ataagtattg
    20101 ataataaaat ctgtcttctt aaatatactt aaataaaact tctataatta tatcaaagta
    20161 ttaatattca ctctctattg tctctcctac aagtctattt tctccattta gggtatatac
    20221 tcctgatata gttggttgta tgtattttct atccatatat ggttcttcta aaactctttt
    20281 ttctgctagc atcgtccaaa atacactata tccttgttca ttaagatatt ttaagaaaat
    20341 ttccttatta ataaagaatc ctatctcttc attaagtaat tcactacttt caaaacaaac
    20401 aacttcacca taatcattat atagaatcga atctccctga ccatatctca atttcaaccc
    20461 ataaaataga gtactacaag gtttatgcca tgtgccagaa aagtcttctt gaaatatgtc
    20521 accttctcgt tcagtagtat aactataagt tggcaataat actttataat ccttttctaa
    20581 gatattctta tgttcatcta tttgtaccca ctcttctcca caataatatg aattttgaaa
    20641 aaagtaatat ccatctgccc aataatattc cttattataa agagtataat tactattagg
    20701 ttcagtaagc catctaccca taaagtcttt tccctttaga gcattcacta ttggttctag
    20761 ttggtcattt ttaattatat agctattgat taatacccac atgtcttttt caggattttt
    20821 atagttctta tttttaaaat cattttcctc cttccaagta taccatccat taagtaataa
    20881 aaagtcttga tttttgtaaa cactatttac catatcattt atgcttggta aatcactaaa
    20941 atctcctaac cactcattat taggtattgg agaaaattga aataattgat tatgtactct
    21001 tttattgtta ttattattta ttactgtcat gacagttgga tcaatattcc taatatctgg
    21061 ctcaaatgta cccttacaat aaatttcttt tttagtacca taagcatctg tatacacttc
    21121 tatcttataa ttatcagcag cttgcgctgc aagttcatat aatgcaatcc attgatattt
    21181 ctttcctatt ctttcatatt tactatctct taatctacca ttttgtactg ttctatcaaa
    21241 tttaccatgt ttatttacat catatcccat atcaaaaact ttcttaatag ctatattctt
    21301 taaatcgtta tagtctagac ctttccattt atggaaatag tgttggaaca tatatcttcc
    21361 aaaatctcca taccatcctg gttgtccatc tctagtatat tctacttcca tagaatttaa
    21421 gatagtgttt tgactccaat aataatcttt aaaatctgat gccttatagt catacttata
    21481 tccctcaatt tcttcatcag ttggtacttt aggaaaaatt gatttatatg gtggttcaac
    21541 attcatatct tttaatactg aactatcaat tttatatttt gcataatcta caatattttt
    21601 tgcataatct cttaataaaa tattgggata aacataatct acatcaaata ttttattata
    21661 aacataaact gccaatgcct ctatcatctc ttctgattgc tctgatacaa cacatccaaa
    21721 tgcaactgca tataatcgtt caataatata tgggtcatct acatcttcaa atgttttaag
    21781 taaatctatt acaatatcca ttttccctgt taatagattt acaagagctt ttgtactttt
    21841 atctcttaag tctctatttg aagaaattaa aaacgttgca atcatcatag ctgacaatct
    21901 aattgtttca tttgaagtat tatcaaaacc ttcaaaatca aagcaccatc ctaataatcg
    21961 cttaatagaa gactcttctt cttcataaac ttcattaaat ataggtataa agatagcatc
    22021 tctatctgcc atagtatttt gtaaaatata ttttactata taatctgcat ttaatgtatg
    22081 attaaccttt gtagaaatta agataagtac attataaaaa tctattttat aataagattt
    22141 acctaaaact attttattaa tataatctag tgttttttca gtaattgtag atttcttacg
    22201 ccattttagt gcattgataa atgcactaat aacattataa tttgtttctt tatttttaaa
    22261 aacttcaaaa atttcattag gtatatctga gcctgtctct tcagataaaa caattgccaa
    22321 tacttctaat atatcctcat attctactaa atatttatac ttatgtgaaa aatctactac
    22381 cccaatttct tttaactctt taaccaacaa atttgcatat aaataatctt ctaacttctc
    22441 atatgtcaca tgcatatatt cttcatcatt taaattgact gttttattaa ctattccatt
    22501 tgctatgagt tcatctatta tcacattgtt aatcttatac ttacttgcaa tatttattat
    22561 aatctctaca ctcttgtttg cgggtattaa attattccca agaccatctc catatttata
    22621 tttaatcatt tcattaagta cttctgtaac tacattggca tgtctactat aattgcatga
    22681 ttcagatatt ctaagattaa gtatattcaa ataattttta taaatatctg taaaactaat
    22741 agtatctaag ttaatctctt ctcctttaaa agtttcacac ataattctca aaaaaagagg
    22801 gtttctaaat tcttgatttg gcattggaat attagaataa ggtattccat aataatcaaa
    22861 atactttttc atagctttat gttctatact agaaaatcct tgatgctcta taaaaaccaa
    22921 attctctttt atcttgttat tattatctat taaagatggt atatattcac ttcttattga
    22981 taatattagt ccaatccatg gatatttctt tatctgttct acaataccat ttaaataata
    23041 tttccaaagt tcttttcctt gaccttcatt caatgcatct ataaataata tcacacgctg
    23101 ttgctctttt tctcctattt cattaagtat ttctaataat tcttcaaact cacactcaat
    23161 ttctaatatt tctaacatat gtttaattgg tgttttatcc aacttaaaat gttgccctaa
    23221 aaataatata gacttatgcc catccatatt tcttttctca atagtatgtg caattatatg
    23281 agatttcccc ataccacctg cactatgtaa taaaatataa gggctattaa ctacttttat
    23341 ttccttagaa tccaaatatt ttatatatac atagatatct ttttgagtct gcttcaattt
    23401 gtatatttca tcttctcttt ttttactttt ttcacagtct tcatttataa ttatattttt
    23461 aaaattattt attctatcat caagtgctgc acttattttt tcaaagtgct tttttaacaa
    23521 cttgatatct aatctttcat tagctttgtc ataaaattgt tgtattattt cttctataac
    23581 tagtacatct acttccactt catttatttt ctgtttcttt atacttgata gaactttatc
    23641 tgttttttca tcaaaacgtt gtttaaattc ttcatttttt cctaatgcat taaacgtatt
    23701 ttctaaactc aattctacat tcaattctgg taaatatcta tctccaaggt tttttatctg
    23761 tatattattc tgattttgaa accatttctc tgttaatcta caagataaat tagttaacct
    23821 actttccttt aaagacctat cctttaatct tctatattca tctggcaaaa ctatttccaa
    23881 aattcgttca agtattattc ttacacactc atgcttacct tcaggataca taatggtttg
    23941 tatataatac tcattttcta actctattcg tctatgtttc tttttctcac tactaactgg
    24001 aataatagca taatgacccg ttcctgcctc tgatacttgc tgtaataatt ccaacggtct
    24061 atccttttcc aaactacatc caagaaataa caactcttta cttgtatata cttgtgtaag
    24121 catctttctc aattcatcat tactatatgc tttttcatat tgttcttttg ttaacacaat
    24181 agatgttgta ggctctgtaa tatccccatg aattttatac aatactaatt cattatttct
    24241 aagtgcatta tttaatgctt caaagtgacc tggatgtgac actaaaactg ttttattgtg
    24301 taatccataa tttttttcta gtactttatc ataattagta gttataatta atcctgagcc
    24361 aaaaattata ggaattaaat agacacattt atcaataaaa tcgtctttat cttttgcatc
    24421 cagataacct gccccaaaaa ctttttttaa atgtttagaa aatctaactt tcgccaattc
    24481 ttcatataaa aattctgctt ttttctcata atcctctatt ttttcaaata aaattttatc
    24541 ctcatcttct aaatattctt cacttgtgtt atttaaaaat gtactccatg aaggatatat
    24601 gtctttaaat aacatagaca tgcctgctcc aatatatggg actacataac catctttaat
    24661 tgcatttacc agttcatcaa aatttttttg attgtaaggc ttattaaatt ccataatttc
    24721 ttcaaatgtc attattccct cctaaactat ctcttaataa tttcaaccat aattcctatt
    24781 ttataatttt attatatcat tccattccat ttttttacta caattctatg ttatagaatg
    24841 aattcactta cttacatttg ttaataatat aaaactttct tttaagataa ttaaaattta
    24901 tacttttaaa ttatggataa aaatggaatg ttataacttt taatgtatta ctaatattaa
    24961 caattttaaa aaataatact attcttattt tatgctataa ttatattttg cataaatatt
    25021 attgatattt tataaatata attatactta tatctcatac tcaaatattt tatataatat
    25081 ataagtctaa attaacttgc aatataaaag cgcctcttaa tataggcgct ataatgttat
    25141 aaatttttaa ttatatattc caatgaacct ttatcaacca tatctaaatt aaatatataa
    25201 tccatcttat caaatgcatc tcttaatgga atacttgatt caagccatcc taacccatct
    25261 gtaatccaac aaaatgtaaa acctccatct tttatatact tatctaactt agtaaactca
    25321 tttgcaacag attttaactt agaacctcca ccattataaa aattaacttc tactaaaaca
    25381 atttttccat tattatttat agcaaagtca tactttcttt tactcttatc tgttggaact
    25441 tctatagacc atttctcact tatttttttc actgtagctt gtgttaaata actccaatta
    25501 ttcttttcac acatattctt tacatatctt tctacaagag tttccatact acttccagtt
    25561 ctattttttc tagcattcgt atcaagccca acctctactc caaacacata atctactaaa
    25621 ttttttatat ttttttgttt taataaatct aaaaacttta tttttttaag aaattctgta
    25681 gctaattcgc tttcttcatc acttatactc tttctcttct taaaattaaa cagtttatat
    25741 ttaaacatat cctcatctga tggatctagt attttgaatt cattatctct actcgctatt
    25801 actattggta tcacactaag aacttctgga tactctttta ataaattttt agtttcgttt
    25861 tctatatctt cttttcctat aagatagttt aagatattta actgaacctc tatctttcta
    25921 gtattttcca aagctttatt ccagttaaca taataatccc agctagctat agtacctttt
    25981 aaattttcaa gtaattcctt aaatatttca tccttactct tatttttatg aatattctta
    26041 accaattcca tttgattccc cacctcttca taattagtaa ttagcaattc agttataaaa
    26101 cctcttccat tccccttaga atttatgaat cttttagcat gtactctttt tatattaaaa
    26161 tctgaataca aatcatcaaa gaaagtatct tcttcatcta aaacttttgg atcagaatta
    26221 cttaacatca attttgtatc tattttatct agaactttat aaaatttact taactcaatt
    26281 tgactatcat cattaaaatt acctttgtta taggaattaa atcctcctat agttactggt
    26341 ctatatggtg gatctagata cacaaaacaa tttttatcta ttatattttc tagatttaaa
    26401 taattcttat ttaatatttt tacttttagc tctcctcgag aatctctttt atttaaaagc
    26461 atggataatt tttcaagttc atttttatca aaaaaactag gatttttata tcttccaaaa
    26521 ggtacattaa attcacctcg agaattttct ctatataatc cattaaaaca tgttttattt
    26581 aaaaatataa aatatgaagc ttgctttata caatcttcat tttctatatt tttttcattt
    26641 gtaagtatat taaatctatc tctaatatca tagtacatct tttctctatc tgaagaacct
    26701 tcttcgtaag atatgtattg ttcttttaaa ttagttagtt ctgttattaa ctcttccaaa
    26761 tcatctctga ctttaatata taaattaatt aacttactat ttatatcatt aattacatac
    26821 ttgttgaaaa tgtcctcttc taacaaatat agaaatagtg cacctgcacc tacaaaaggt
    26881 tctatataag tcatggaact aaaatcacaa cctgtaggca tttgttttct tagaatatca
    26941 agtagctgtg ttttacctcc agcccatttt aaaattggtt tcatgcaaca cctctctcag
    27001 ttatattgtt atataattat ataaaataag attctaaaat acaagtactc atcagaacac
    27061 tatatttata tcaaatcttt ccaaaatcta agtattattt tatcctaaca cttttcaaaa
    27121 cctctaaata atatacaata ttctctaata tttacttact aaaaatttaa atctatcttt
    27181 aagtataacc taaaacagat tataagttac gtagttttta atataaaata tacttctaca
    27241 agtaaagctt taaatatcaa ttacttattt cataattaat gactatgtac cctcaaaaaa
    27301 acctcatttt ctatggttgg ggtacggttg gtggatttca tcaccaaaat aaaaaatact
    27361 agtcaataaa gactagtatt tccaagtatt tcatcattct tttttcaaaa ttggtggaga
    27421 cgaggggagt cgaacccctg tccgcaaatc ttttccttgc tgcatctaca tgcttagcca
    27481 acttcactaa tatctcacct cacatagcgc caagtggcag gctctatgct tagccagtcc
    27541 caattaatct acttcaggtc gagacacccc taaagtagtt ccctgcataa tgacgtccag
    27601 tcttagtcgg caggaggact aagagggacg agcagcaact aggctgctat cgcgaaatta
    27661 tcgtctgcgt ttattttaaa gttccccagt ttttacgtga cccagagtaa cacgacatgc
    27721 agcctcaagt tccaaaccca cgtcgaaacc tttacgcccc cttgagtagt ttatagtcca
    27781 gtagactttt cgcaaacttt atcaccattt ttattaaatt tttaatgtat atataatata
    27841 atacttttaa gaataaaaat caatgttatg ttctagataa taaagaattt tattctaaaa
    27901 aatacagttt tatctagttt aatacttacc tgtcatttct ctttctatac gtctttgtgc
    27961 atctttctta gccatatctt gacgtttatc atatagtttt ttaccttttg ctaaggcaat
    28021 ctctacttta actttaccgt tttttagata caaactaagt ggtataagtg aatacccctt
    28081 tatagtagtt gctccaataa gctttcttat ttcatgctta tgaagtaata gttttctaac
    28141 tcttaaagaa tcaacattga atatatttcc ttgctcatat ggacttatat gaacttgttt
    28201 taaaaatact tcgctattat ctacagatgc aaatccatca cttaggttaa ctttgccttg
    28261 tcttattgat tttacttctg ttccttttaa ttcaattcca cattcataag tttcttctat
    28321 aaaatattca tgtcttgctc ttttgtttgt tgctaatatt tttttaccag ccatataaat
    28381 ctcaccttct ttgctagaaa tttattccat aaatattaga aatttactaa atatttaatg
    28441 ttgccaaatt atttgactaa cttgtatgat aacatattta ggcattttag tcaatatttc
    28501 actgatatat taagttagtt aggctatata taattaagta atataaatgt atgaaaatag
    28561 ctaaaaaact acttcgaata tacttaatac taaactaact ctaaccagta atactaattt
    28621 ataaatttca aaacaaaaat attacatatt ataaatcttc tatcttctat cttctatctt
    28681 ctatcttcta tcttctatct tctatcttct atcttctatc ttctatcttc tatcttctat
    28741 cttctatctt ctatcttcta aataatttta acatgcccat aaaatataat acccacaaat
    28801 gataaataat actcaaaatg tctattgaaa taactataca tccttaaata acttaactta
    28861 aatctaaaca tttcaaaaac ttcttaaaaa tatgtaaaaa tttgatgata aagtagcgat
    28921 tttttcaaaa aaaatgtaat atagagttat atcttataat attttagaga taaattttat
    28981 catagtgggg agaaatttgt atggatttaa gcaaaaaagt aaaaatttta gaaaatgcat
    29041 cagatggcaa aagcgaattt gagatattag aatttgaaaa acttgaggga gcttctagcc
    29101 cattaatggc aatgggatta tattttgcta gagaagctgg tttgaaagct agacaaatta
    29161 agataaaatt aaataattca tcaataaaaa cagaagctgg tgcattatac tattataaag
    29221 gaaatatatc ttctgaaact aagattggtg gtgttggagg tctttttaaa aaaggaatat
    29281 caggagcact tactaatgaa tcaatgatga aacctgtata caaaggtact ggagaagttt
    29341 atttggaacc ttcttttaga cattatttat ttatgagtct tgataatgat tctataattg
    29401 ttgataaagg attattctat tgttgctctg atacaataga agtaaaagca tttacacaaa
    29461 agaacttctc atctgcttta cttggtggtg aaggcttctt ccaaatagaa ttaagtggta
    29521 ctggtgtaat cgttctggaa tgtgttgtac ctcaaagtga aattgtagag tatgaattga
    29581 aaaatggtga agaattaaag gtagatggta actttgcaat agcaagaaca tctggtgtta
    29641 atttttctgt tacaaaatca gataaatctt taattggttc tgctttaaat ggtgaaggtt
    29701 tcttaaatac atttactggt aatggtacag tttggctagc tccaactcaa gtaatgtatg
    29761 aaaaactaag ttttggagca atgcctacta atgataatat gaataataaa gtttctaagc
    29821 aaaaatagtt gttttataaa tatttattaa atcattattg attttataaa gtcactataa
    29881 attttattag attattatta taaaatcaga gtgtggaaat gtttatgtgt attctttaaa
    29941 taaaaatttc cacattctgt aaggttatta tacttgatat ataaaattca atttaggaac
    30001 atagtctaac atttataaac atattaaggt aatgatttct cttggtaatt attctcatat
    30061 cttattcttt gattatattt atcttattcc tagcccttat gtcatattat atttcttatc
    30121 ttattactta taattagcat taacttatct aaaatcttgt atttttttaa tagtaaagtt
    30181 tacatctata ttaaaaagtt tacatctata ttaatttcat aaaacaatca aggtagtcaa
    30241 gagattcaac tttacttgat tttaaaaatt taagtgaatt tgttcttata cacatctttt
    30301 taaaattata tctgtagaaa atatcattta gagctataat taaattaact tattaaattt
    30361 tagaaaattt attaaaaaat ataagttaaa ttaatatttt taaagattct tttttgtaac
    30421 tactagaata gtaatttagt agttattgta tctctaaagt ttaagcatgg atagatatac
    30481 atttgataat ttgcctataa tttacctact acttggatta ttggagcaaa tacaatatat
    30541 taataataag ttcctaaaac caataaatta actaatacac ataaagatat tgatgttgat
    30601 tatacaacta taagaaacgg atttaacaga atttaatcaa gctaagaaat tatatatata
    30661 tcgtgatgtt tttgaattag aaggtaattc aaaattagtt tatagtcttc tgtcaatcca
    30721 ataaaaagta cagggtacaa gaattgttag taaaattttt aaagatttta tggataaata
    30781 taaatagttt tacttatttt ctaaaacttt aaaataccat taattacctt aaatatttta
    30841 ataggaggac atatgaattt aaataaagtt aaatttactg aagaacatgc tattgaagtt
    30901 actaattgga aatatgaagg taaatattca atatacaatc tacctccatg ggaggaaatt
    30961 aaaaagaaga atttttcact agcaaaagaa gataaaagaa aaaattttat aagttttata
    31021 aatgacaata aagaattgat aggttttata aacttattag atgaaggaag ctctgtattc
    31081 tttggtattg gtatgaaacc gaattattgt ggaatgggaa ttggtaaaga aataattggc
    31141 ctaggattac aagaatgtag aaataaatat agtactaaac caattgtatt aaatgtaaga
    31201 acctggaaca tgagagctgt aaaatgttat gagtctcaag gatttaaaat agttgagact
    31261 aaggtacaaa aaacgcattt aggagatgga gaattttttg ttatgaggta tcaatagttt
    31321 ataacaatag tcttattgtt aatacaacaa ttaaaatgaa aaaatacata tgtgtaggtc
    31381 atagcaataa gtgtctttga aatataaatt tgagagcttt tgataaaatt ttgtatacat
    31441 atatatttta tactacggat atataaatct atctacatat ataaagagat tgtaagtagg
    31501 tttgtgtata taaaaataga tttatatttc ataaatgtac tttttatttg tattaccttt
    31561 attttatcta agctctcatt ttattatcta atcttccttt ttactggttt tattaagaga
    31621 gatgcaatta tcaacacaac acttccaagt atcagccaat atttctcatc aaaactacct
    31681 tgactcatag acattataaa aaattttcca acatacttgc ctttagtcat catatttaaa
    31741 attaaatatc ctatagatat catataacct atgattgtat tattaaataa atttgagaaa
    31801 aacattccta aacttcctat aaacatagct gatgcgaaac ttccaataat atactcaact
    31861 actggaaaat tacatccaag atatattaaa acatttacaa aacctatgat taataccact
    31921 atacctataa ttgacatcag tatcctaatt aattgtacaa taacttgaga taatgctttt
    31981 gaagatacta tctcatcaat ttcttttgat tgctctagcg aaaatacagg taccaacatt
    32041 actatcccta ttattgcaac ataattttct aaacatatag ctgttgaaat tctgtctaaa
    32101 ttagctactc cttgtattag aggaaccata catagcaata taattgaaca tattaaatta
    32161 gttaaagtgc ttaatttgaa gttttctttt attagaacta aacagttttg aaaactttgc
    32221 ccaaacatca agattccccc ttcttttttg ctcatataag aatatagcta acaaaacaag
    32281 caccaatgct cccaagctta tcacaattct attaatcata atttgattga agttttgtat
    32341 aataatatcc ccatttaata cactattatg tcttatcatt agccccattg ttgaataatc
    32401 acctttgagt cctgtagaat ttatactgta aagccaccaa attaattgca caataattgc
    32461 tactggtgta tctgttaata tagtaatact cattcctaca gctgtaacta tcataagagt
    32521 tggtagtatc caccataatg tatattttat aaatgctaag ttatcaatag atataccttt
    32581 atctttagca aagaaaatca aaggaagtaa atctttcata cctaaaatta atacaggcaa
    32641 tatcatcata aagacaagtg caaaatatct tgataaaact attttgcatg aagatacttg
    32701 ttttgaataa ataatctctc tcattcttga acgcttatct ttaagtgaca taaaaactgc
    32761 cacaaatact ggaaatatac ttaaaactat acctatataa tcgcaaaaaa ttcttgcata
    32821 cccattacta actttatctt tttgtattgt atagttgtaa ttcttcatag cttcatcata
    32881 ggtaactgga actactccaa atctttgtaa cttgtcaaaa gcatatgcag accctcctcc
    32941 taaaatgtcg tctactcttt gcattatttc ttcaaatctt tcaagagata ctttagaata
    33001 atctattttt atactttcat cagttttcca aagtgaattt atttcgctaa tacttttacc
    33061 agttatttct tctatatatt tttctatggt cttcgtttta ttttggtcta attttatata
    33121 cttaactacc cctgttggat acgttgtata tgtgtttttt tgatattctc taattaggtt
    33181 tatagttgca tttggaatga ccttttctgt tttcatagat tctttttgac catatggata
    33241 ttgattgtgt acagaataat attcctcaat attctctact ttttgtggag caactaatgg
    33301 atttccatca ttaggaatat ttttacttac atcatttgaa actgaacttc caagttgaga
    33361 aatatagaaa aaaactaaaa ctacaataaa aatataatat accatactct ttaatatatt
    33421 tttacattct tttataaata gattcatata ttatctcctc ccattataag catatagcca
    33481 tcttcaatag ttggattaca atttactgct gtctcaaaag gtttatcatc tgatataatc
    33541 ctaagtatag cctttccacc atgagtcaac attcctataa ctataaatct actttttata
    33601 ttttcaatgt cttttttatc tacttcaata ctatatactt tcccttcagc tagttttgct
    33661 aatgcttctg ttgagccatt gtatatgact tttccactat tcaatatagc tacgttttca
    33721 catgtagctt ctatatctcc aacaatatgt gtagataaaa taacgattct atcatttgca
    33781 atttcgcata gtaaatttct aaatcttata cgttcttctg ggtcaagacc tgctgtcggc
    33841 tcatctacta ttaaaactct gggattatga attaatgctt gtgctatccc aagccttcta
    33901 ttcatacctc cagataaaga ttttactttc acattttgat aattagtaag gtttactttg
    33961 cttaataact ttgctataat ttttcttctt tttcttagtg gtatatccga taaaactgct
    34021 aaataatcca ttgctttata tactgtcatg ttaggataca ttgaaaaatc ttgtggcaaa
    34081 taaccaacca tatttctaat ttccttagta ttctcaatag gaactccaca catatgtatt
    34141 gaaccttctg tttttgataa taaagtggct aaaattctca taaatgtggt ttttcctgct
    34201 ccatttcttc ctaaaagacc aaacatacca ctgtcgattt caagatttat attatcaaga
    34261 gcttgttttt tcccaaatct tttactaaga ttggatactg ctattttcat ttccatatat
    34321 aaatacaccc ccagaaacaa ttttatagaa ttttattttt ataaattttt actgtatttt
    34381 cataataaat tctaaaactt aagatattat ttataaattt ctaaattttt tctaaagatt
    34441 ttaatttttc tgtttttaat taaattaaag tatctttgtt tctgaaattt tttaagttta
    34501 tgaagttata
//
LOCUS       DAMJWC010000044        32216 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMJWC010000044 DAMJWC010000000
VERSION     DAMJWC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32216
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.044"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     regulatory      134..224
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            633..950
                     /gene="flgB"
                     /locus_tag="PC503_002378"
     CDS             633..950
                     /gene="flgB"
                     /locus_tag="PC503_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF2528345.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            958..1362
                     /gene="flgC"
                     /locus_tag="PC503_002379"
     CDS             958..1362
                     /gene="flgC"
                     /locus_tag="PC503_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF2528346.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            1372..1689
                     /gene="fliE"
                     /locus_tag="PC503_002380"
     CDS             1372..1689
                     /gene="fliE"
                     /locus_tag="PC503_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF2528347.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1714..3264
                     /gene="fliF"
                     /locus_tag="PC503_002381"
     CDS             1714..3264
                     /gene="fliF"
                     /locus_tag="PC503_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF2528348.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            3277..4347
                     /gene="fliG"
                     /locus_tag="PC503_002382"
     CDS             3277..4347
                     /gene="fliG"
                     /locus_tag="PC503_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF2528349.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            4340..5071
                     /locus_tag="PC503_002383"
     CDS             4340..5071
                     /locus_tag="PC503_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF2528350.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIRKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            5075..6394
                     /gene="fliI"
                     /locus_tag="PC503_002384"
     CDS             5075..6394
                     /gene="fliI"
                     /locus_tag="PC503_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF2528351.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            6426..6872
                     /gene="fliJ"
                     /locus_tag="PC503_002385"
     CDS             6426..6872
                     /gene="fliJ"
                     /locus_tag="PC503_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF2528352.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDNVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            6900..8105
                     /locus_tag="PC503_002386"
     CDS             6900..8105
                     /locus_tag="PC503_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF2528353.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNNKFEDNLYKTTDHKNV
                     KDRRETSKQNVSSDRPGNSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNLELNGANTNNPNDIE
                     NLDIMKLRELLENNASEDIQVISKTTENDTKSIDLYSFDSNRMDTLNSNKQKDDSSDI
                     LEKLAGLNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSNQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            8123..8731
                     /locus_tag="PC503_002387"
     CDS             8123..8731
                     /locus_tag="PC503_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF2528354.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEDEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVDVKYEKLLKIGEVEANSGEENDSSEQESPEEV"
     gene            8758..9741
                     /locus_tag="PC503_002388"
     CDS             8758..9741
                     /locus_tag="PC503_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF2528355.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9754..9957
                     /locus_tag="PC503_002389"
     CDS             9754..9957
                     /locus_tag="PC503_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF2528356.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9957..10775
                     /locus_tag="PC503_002390"
     CDS             9957..10775
                     /locus_tag="PC503_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF2528357.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEINEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10765..11460
                     /locus_tag="PC503_002391"
     CDS             10765..11460
                     /locus_tag="PC503_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2528358.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKEDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPKLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11472..11915
                     /locus_tag="PC503_002392"
     CDS             11472..11915
                     /locus_tag="PC503_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF2528359.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11930..12304
                     /locus_tag="PC503_002393"
     CDS             11930..12304
                     /locus_tag="PC503_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HDF2528360.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            12305..12970
                     /gene="fliP"
                     /locus_tag="PC503_002394"
     CDS             12305..12970
                     /gene="fliP"
                     /locus_tag="PC503_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF2528361.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12983..13252
                     /gene="fliQ"
                     /locus_tag="PC503_002395"
     CDS             12983..13252
                     /gene="fliQ"
                     /locus_tag="PC503_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF2528362.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            13264..15078
                     /locus_tag="PC503_002396"
     CDS             13264..15078
                     /locus_tag="PC503_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF2528363.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLINNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFIDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVNTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            15087..17162
                     /gene="flhA"
                     /locus_tag="PC503_002397"
     CDS             15087..17162
                     /gene="flhA"
                     /locus_tag="PC503_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF2528364.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            17137..18153
                     /gene="flhF"
                     /locus_tag="PC503_002398"
     CDS             17137..18153
                     /gene="flhF"
                     /locus_tag="PC503_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF2528365.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            18150..19028
                     /locus_tag="PC503_002399"
     CDS             18150..19028
                     /locus_tag="PC503_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF2528366.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVGVCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            19042..19743
                     /locus_tag="PC503_002400"
     CDS             19042..19743
                     /locus_tag="PC503_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF2528367.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDTEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19759..20181
                     /locus_tag="PC503_002401"
     CDS             19759..20181
                     /locus_tag="PC503_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2528368.1"
                     /translation="MIQIILIVVSILIIVTIVINLQKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            20166..20351
                     /locus_tag="PC503_002402"
     CDS             20166..20351
                     /locus_tag="PC503_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2528369.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            20392..21165
                     /gene="flgG"
                     /locus_tag="PC503_002403"
     CDS             20392..21165
                     /gene="flgG"
                     /locus_tag="PC503_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2528370.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            21186..21947
                     /gene="flgG"
                     /locus_tag="PC503_002404"
     CDS             21186..21947
                     /gene="flgG"
                     /locus_tag="PC503_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2528371.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21970..22851
                     /locus_tag="PC503_002405"
     CDS             21970..22851
                     /locus_tag="PC503_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2528372.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22854..23228
                     /locus_tag="PC503_002406"
     CDS             22854..23228
                     /locus_tag="PC503_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2528373.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            23260..24663
                     /locus_tag="PC503_002407"
     CDS             23260..24663
                     /locus_tag="PC503_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2528374.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYNSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24779..26716
                     /gene="htpG"
                     /locus_tag="PC503_002408"
     CDS             24779..26716
                     /gene="htpG"
                     /locus_tag="PC503_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF2528375.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            27104..28234
                     /locus_tag="PC503_002409"
     CDS             27104..28234
                     /locus_tag="PC503_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2528376.1"
                     /translation="MNFNYNLPVNILFGSGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            28461..29483
                     /gene="splB"
                     /locus_tag="PC503_002410"
     CDS             28461..29483
                     /gene="splB"
                     /locus_tag="PC503_002410"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF2528377.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            29665..30576
                     /locus_tag="PC503_002411"
     CDS             29665..30576
                     /locus_tag="PC503_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2528378.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            30591..31007
                     /locus_tag="PC503_002412"
     CDS             30591..31007
                     /locus_tag="PC503_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2528379.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(31107..31499)
                     /locus_tag="PC503_002413"
     CDS             complement(31107..31499)
                     /locus_tag="PC503_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528380.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            31640..32035
                     /locus_tag="PC503_002414"
     CDS             31640..32035
                     /locus_tag="PC503_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2528381.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        13227 a         3419 c         5888 g         9682 t
ORIGIN      
        1 tttattataa aattgtaaac tatagtgttt ataatctttg taattattgg taattaaatt
       61 taaaaaataa aatatttaat tatacacaaa aaagatattt aaaaaatttg ttatttattg
      121 tatacttaag ttaaaactaa ataggcaaat ctagagaaat ctagtgacgc aaagctatag
      181 ggactaaggt ttatatacat aaactatgtc agccagttgc caaaaagagt cctaggtgta
      241 ttgtatacct aagaaaagtc tataatgact gcctttttgg cagtcatttt gttatggaaa
      301 aatcacttta tttcagtaga aaatacacat aataacatat tttaccaatt ataacataaa
      361 ataaagaaaa attatctcaa aaagttacta ttttacaaaa aagagcaact tttcgaagaa
      421 atatttaaat acatattaaa atttttttat attttcatgg gacttcatta aaaaaatatt
      481 agttttctta ctaaattgat acattattgt attaatgtaa tggaaatgcg attaatttaa
      541 ataaataaag aagtcatttt ttgtaatata gcaacttcat tttttttatt aataaacaaa
      601 atagataaaa tatattttga ggaggggtga gtgtgaatac atatgacatt ataaaaatgg
      661 gattagatgc aactaatcta agaagtcaga caatagcaaa taatatagca aatataaata
      721 ctgaaggata taaaagacat tatataactt ttgaagaaac actaaatgat gctatgccta
      781 aaatagaaga aaaaacagac aattctaaag gtttaagagt agatggtaat aatgtagaca
      841 tagaagaaga aaaagtaaat caagcaatgg caacattaca atataatgct ttgataagtt
      901 ttgcaaatgg aaaaatagca atgaccaaat caataataag tgggaggtaa ttagaagatg
      961 agtgtgttca gtggaatgag aatatctgct agtggattaa cagcagaaag tttgaaaatg
     1021 gatatcatat catccaatgt agctaatata aatgctacaa gaggtccaaa tggagaagca
     1081 tataggagaa aagttgtttc atttgaagaa aactatgata ataaattagg tatgctagga
     1141 gtaaaagtta catctgttga agatgataaa tcacctctta aagaagtata tgacccatct
     1201 catccagatg caaagccaaa tggatatgta gaatatccaa atgtaaatat attggtagaa
     1261 atgacagatt taataacagc ttcacgagca tatgattcta acgtagatac attgaatgct
     1321 cagaagtcta tgatatcaaa agctttggaa ataggaaagt agggataaat tatgccaatt
     1381 acacaaatta acaatttaat gcaaggtgca aagttagata atttgattgg agaagcaaag
     1441 ccattaactc ttaataataa agaagaaaaa aagaattttg aagatgtaat aatagatact
     1501 atagataaag ttaattttca acaagtaaca gcagatgata tgaaagaaaa atttataaaa
     1561 ggcgaagatg tttctatgca tgaagttatg ttaataggtc aagaagcaca actatctatg
     1621 caatatttaa tagaagttag aaataagatt catgatgcat atcaagaaat gaataaggtg
     1681 caaatttagc cttttgaaca ggagtaataa tcaatgataa ccagttttaa aaataagatt
     1741 aaggagcaag ttgctaaatc taggacaaag ataagttctt taaaaaaggg aactaaaata
     1801 gcattaggta taggggttat tgctatatgt ttagcgctag tatttacagc aatatctgcg
     1861 agcaaaaata agtatgcagt cttattttca gaactagatg ctcaagatgc tgcagatata
     1921 tcagcagagc tagagtctaa aaagatagat actaaggtaa aaggaagtac gatttatgta
     1981 cctagaacag aagttgataa gttaaggctg gagttagcgc caagtcttac aggtggttct
     2041 aaaggatttg cactaatgga tgatagttca tcaatagggc ttactgatga agaatttcag
     2101 attaagaaac aaagaatgat acaaggtgaa atagaaaaaa caataaagag ttttccacaa
     2161 gtggaagaca ctagagtaca tataacattt ggagagtcat cagtatttga gaaggaggct
     2221 gttccaggga gtgcagcagt ttatttgatg ctaaaaccag ggacgacttt agaaaaaaac
     2281 caaataaagt ctgttatggc acttatatca ggaagcgtta caaatatacc agagaaaaat
     2341 gttcaggtta ttgataacaa aatgaattta ttatctgaag gtattttgga ggatgaaaat
     2401 gttgatgaaa ataatcaacc aataaatagt ggcattagtg ttgataaaaa taaggcatct
     2461 gaacaagcat tgaataaaca actagaaaag tctattttag aaatgctaga accgatattt
     2521 ggtaagggaa aggtgaaagc tacagtaaat gctgatttaa gttttgatac agctgaaaaa
     2581 actgagataa aaattgaccc tgataaagtt gcaataaagg agacaaggtc gaaaaattca
     2641 tctaaatctg ctgcaaataa tgttcaaggt gtagatgcta acatgaataa ccaaggaaat
     2701 aacaatggta ctaatacaga agatagttta gatgagagtt ttgagtatga aacaggtaag
     2761 attgaaactc acactatagt tgcgcctgga gaacttaata gattgacagc ttctgttgca
     2821 atagatggaa aaatagctaa aggtgttcaa gctgatgtag aggatattgt taataatgct
     2881 ataggtatgg atggagcgag gggagatact cttagcgttg tttcaatggt atttgaccca
     2941 gaaggtaaga aagaggctaa acaagagctg gaagagatta aaaaagaagg atttaaaaag
     3001 aacataataa aagcagttat tggagtagta gcagtaatag cagttggagc tattggatac
     3061 ttaatatata agaaaagaag tgaacgagaa gatatggatt atgaagatga agattatatt
     3121 tctaaatctg attctgttga taggaaggat aatcctctat taggagatga cccagaactg
     3181 acattagagg aagctgttaa aatgtatgca gaagaaaagc cagaccaagt aacagagata
     3241 ataaagactt ggttaaatga gtaaggggga tagaaagtgt ccacggaaat tacaaatgtt
     3301 aatgcgtttg acttaagtga tataaatgaa agtgataaga atgagaaggt agaaggtgag
     3361 ggtttaaaaa aagctgctgt attattaatg acattaggcc caaatgtgtc tagtgatata
     3421 ataaaaagct tgcctgataa acaagttcaa aaaataggtt tggaaattgc aaatatttct
     3481 tcaatagctt caaaagaaag aagagaaatc ttaaaagagt ttgtagaaat aaatagggca
     3541 aaagattatg ttatagaagg tgggcttgaa tatgcaagag agttattaag taatgcttta
     3601 ggaaatgtta aagcaaacaa attacttgaa ggtatatcaa taaatacaag tacaaagcct
     3661 tttaaacata ttataaaact agatgtaaag aagatattag aaatacttag gaatgaaagt
     3721 gcacaaacta tagccgtttt acttgcacat atggaaccag aaaatggagc agaagtttta
     3781 tcatacttag attttgattt acaaaatgaa gtagctatga gaataagctc aatgggttca
     3841 atatctccag aagtaataaa ggtaattgaa agttcattag aagataaatt acattcaata
     3901 agtggtgatg attttaatga ttatggaggg gtgtctacct tagttcaaat attgattaat
     3961 tctgatagaa aaacagaaaa gaatattttg ggaactattg aagaacaaaa cccggattta
     4021 gcagctcaaa ttaaatctca tatatttgtc tttgaagata ttgtcaagtt agatgatata
     4081 agcatacaaa aagtgttaaa agaagtgact atgaaagatt tagtatatgc cttaaaaggt
     4141 gtagatgatg agatttcaga tgctatatat agaaatcaat cttctagagc agcagatgca
     4201 cttaaagaag aaatggaaat ggttggtgtt ataaaggtta cacaagttga ggcttctcaa
     4261 caaaagatag ctaatatcgt aagaaaactt gaaagagaag gtgccataac tattgtaagg
     4321 aattttggtg gtgactttgt tgaataataa gattattaaa agtaaaaaag cattatataa
     4381 aggagtgcta gatttaacca taatagataa agttagagtg ggagaatcaa atgtaaataa
     4441 agaaaatgat tgtagattta gggatgaggt aataaaagaa gctatagaat ctgctgagat
     4501 aagaaagaat gagatattag aagaagcaaa aatgaatgca caaaatatag aaaagcaagc
     4561 atatgaaaaa gggtatagtc aaggtcaaaa aaatggatat gaagatggat ataaagagtc
     4621 atatgatgaa tatacccaaa aagctaaaga tgaagcagat tttataaaaa atcaggcaga
     4681 cttaatacta ttacaagcta atgagaagat gactgagtac ataaaagaaa aaaataaaga
     4741 gattgtaaga cttgctatta atatggctag ttctgttcta aaaaagcatt tcgaagatga
     4801 agaatctatg agtgatttgt taaagcaaat tattcaagat tatgaaggaa gtagttcatt
     4861 tatagtaaga tgtaattctt tctataaaga taatatagag aaagagtttg aattattcaa
     4921 agaggaaaca tcactaaaat caagtgtatt tgttattgca gatgatagta tagataaagg
     4981 caatgctatt atccaaaagg aaaatggaag aataatagtt ggtattgatt gtgctatgga
     5041 aaaactaaaa gaagaattgc ttggtgaata aagtatgtat aaaactgata tatctataga
     5101 ttttgacaaa ataaataaga aaatagaaaa tttagaactc actatatcag aaggtagagt
     5161 aaagaagata ataggactta ctgtagaagt tgaaggaata aaagcttttg ttggggagtt
     5221 atgcgttata tacaaccaag ttaataaacc agtgaattgt gaagtagtag gttttaaaga
     5281 taaagaagtc atattaatgg cgttgggaga attaacattg atagcacctg gttgtaaagt
     5341 tatttctaag gggatacctt taagtgttat gtgtagtgat aatttactag gtaaagtact
     5401 tgatggtctt ggaaatccta tagacaactc agatgctgtt ttaggagata gatacaacct
     5461 gaacaatgaa cctcctgacc caatgaagag aaaaaagata cgaaatataa tggaaacagg
     5521 tgtaagagca atagatgcat ttactacttg tggtgaagga cagagaatcg gcatatttgc
     5581 aggaagtgga gtaggtaaga gtacgactct aggtatgatt gctaggaatg caaaagcaga
     5641 tgtaaatgta attgctctta ttggagaaag aggaagagaa gtactagatt ttattgataa
     5701 agatttaggt gaagagggaa tgaaaaaatc tgttgttgtg tgtgcaacat cagataaagc
     5761 ccctctagtt aggttaaaag gtgctcttac tgctactgca atagcagaat attttagaga
     5821 ccaaggcaaa aaagtaatac ttatgatgga ttcagtaact agatttgcta tggcacaaag
     5881 agaagttggt gtagcaatag gagagccacc agctcaaaaa ggatatacac catctgtatt
     5941 tgcaatgttg ccaaaactta tggagagaac agggacatca gataaaggtt ctataactgc
     6001 attttataca gtattagttg atggagatga ctttaatgag ccaatagcag atacaacaag
     6061 agggatactt gatggtcata tagttttatc tagagacttg gcaaataaga atcactatcc
     6121 ttctatagat gtattaaaca gtttaagtag gcttatgaat gaaattgctt caaaagaaga
     6181 cataaaaata gcgtcttttg caagagacat gcttgctgag tatagagaag cagaagattt
     6241 gataaatata ggtgcatatg cttcaggtac aaacaaaaaa atagatgaag caatctatta
     6301 tcatgagcat attattaatt ttttaaaaca aggaataaat gaaaagagtt cttttaatga
     6361 aactataagt agtttaagaa gaatctttga ataaacaatt taaaaaaata tttgaatagg
     6421 ttgtgatgga attggataaa aattttaagt ttagattaca gaaagtttta gacttaaaaa
     6481 taaaagatga agaagagata aaaatggaat ttgctaagat tcaacaaaaa aaaatagata
     6541 tagaaactaa tttagaaaac ttagaaagta attacagcaa atattctata agtaaaaata
     6601 atgataatgt tcaaaatcaa aaaataacta ttaactattt gctagcttta aacaactcta
     6661 taatggattt atcagaagaa ctggataagt cgacaaatga acttgaaaaa gctagaaaac
     6721 agcttataag caaacagata gagagaaagt cattagaaaa attaaaagaa aaaaaatatg
     6781 gacagtatta taaagaagaa cagttaaaag aacaaagcac taatgatgag tttgcaagca
     6841 tgagttattt gagaaataga caagttctat aaaataatag gaagtgagga tattattgta
     6901 tgaagataca agcagattct tataatatta ttaaagatat tgggaataga aaaaactcat
     6961 ctaagaataa aaatataaaa aataataaat ttgaagataa tctatataag acaacagacc
     7021 ataaaaatgt taaagataga agagaaacaa gtaagcaaaa tgttagttca gatagaccgg
     7081 gaaatagtga taatgagtgt catttagatg aagataaaag taatcactta gaagatgaaa
     7141 atacatatga aaaagattgt agtaagaata atgaagcttt acagcaatta ctgaatcttt
     7201 taaaagagaa ttataaaaaa gataaagata taaacactat attgaataat ataaaaaaac
     7261 taagtatatc agatgaatta aaacaagaac ttaagcttaa taaaaatata ttgaataaaa
     7321 ttgcaaatca aaatttagag ttaaatggag ctaatacaaa taaccctaat gatatagaaa
     7381 atttagacat aatgaagtta agagaacttt tagaaaataa tgctagtgaa gatattcaag
     7441 taattagtaa aactacagaa aatgatacta aaagcataga cttatacagt tttgatagta
     7501 atagaatgga tactcttaac tcaaataaac agaaagatga tagttctgat attttggaaa
     7561 aactagcagg gttaaatgga aataagagtg gaaattttgg acaagtaata aataaaagcg
     7621 ttgatatgaa taaaattaaa aatgataatg ttaatttaaa acagatagaa tctaatgtaa
     7681 tggatgattc tataaaagct attaagcata tgaaaacaaa tgatatacaa gaattgacaa
     7741 ttaaattaag accaaaagaa ttaggagata tgaacataca attattaaaa gatggtgaaa
     7801 gtatgagagc tgttgtgact gttttcaata aagatgtctt tgactctata aataaaaaca
     7861 tagcagattt aaagcaacat cttgaactta caaatgtaaa tataaaagat gtatcagtgc
     7921 aaatgcatag cgataataca aatacatctg atacctttga taaagcattt gaacaacaga
     7981 atagacaaaa taaccaagaa aacatgagta atcaaaatac aaatgataag cgtaacaatg
     8041 tagtcataga agatgagatt aaagaaaata ttattgatga tgatagagta gatttactag
     8101 cttagtaagg gggaagtatt gcatgtacgg aatagcaacg gctttggcag gaactcaggt
     8161 aaactatagg tcaaataact taagccaact tgaaagaaat attaatgata ttgccaacaa
     8221 acaagttaga agtaaaggaa atcagacagt aacagacaat gggactccaa ttataggaca
     8281 aggtgatgat gctgataaag acttgtttat gaagattctt gtagcacaga tgggtaatca
     8341 agacccaatg aatccacaag acccaacgga gtatgtatca caattagcac agtttgcaac
     8401 tttagaaaaa atgtcagcta tgaatgataa gctagatata cttttagcct taagtaactc
     8461 tactctaata aactctgctt tgagtatggc aacatcatta attggtaaag aagtagaagt
     8521 atctggggaa gaagatgaag atgaaaacat tgtaggagta gtaaagtcca catacataaa
     8581 agatggggaa gtacacttag aattagaagt agatggaagt gacaaaactg tagatgttaa
     8641 atatgaaaaa ttacttaaaa taggagaggt agaggcaaat tcaggagaag aaaatgactc
     8701 ttcagaacaa gaatctccag aagaagtata atattaaatg ggaaaagagg taaatttatg
     8761 ataaaagcaa tgtattcagg tgtaagtgga atgaaagcaa atcaaacaaa actagatgta
     8821 atcggtaaca atgtagccaa cgctggaact acttctttta agaaaagttc agctagaata
     8881 acagattcat tttatcaaac tgtactatat gcaagtgctc caacagcggc attaggggga
     8941 acaaacttag gacaagtagg tgtaggtagt aagatatcaa gtataaacaa agatatgaca
     9001 caaggaaatg tacaaccaac taatagacca tctgatttaa tgatagatgg agatggatat
     9061 cttccagtag taagacaagg aacagttatg tatacgagag atggttcttt taatttagat
     9121 acaggattta aagcagctga tggtgctttg aagaatatta aaggtggaag acttgtaaat
     9181 ggtgatggat atatgttaca aggtatgatt tatgatgggg aatataaagc tgatactgga
     9241 gaatttgtta aaaagggtga tgctaaagga aaagagccta ttgtaatacc acttcaaagt
     9301 ataagtccta aggatggaac agttcaaaat gtactagagt ataatatatc aaaggatgga
     9361 acagtagaat ttttattgag tgatggtcaa agaactcaat ttgtctatga tatacctgat
     9421 ggtgctaagg taggagatac acctgctgga atagataaat taaaaggtac aatacaaaaa
     9481 gtgcaaacat atgcattcca aaatccagca ggactagatg cagaaggagg aaacttgttc
     9541 aagccatcag caaactcagg agacccacaa atagcaggag ctacaggcac aataatacaa
     9601 ggagctatag aagcttccaa tgtagatata gcagaagaat ttacagaaat gataatagca
     9661 agtaggtctt tccaagcaaa cagtaaaata atatcgacat cagacgaaat acttcaagaa
     9721 ataataaatc ttaagagata gtaggtacat attatgataa gagtaacgga tttaaacgga
     9781 agaaaataca tattaaattc agatcttata gtgagaattg actccgtgcc agaaagcagg
     9841 attctcctta caacaggaga aaaaaatctt gtaaaagagt cagtagatga gatagtagat
     9901 aaagtaataa agtataaaag aaaaataaat gtaggttata ttaggagtga aaaataatga
     9961 aaaaaacaga ttcactaaca ttcattggac taatattatc tacagtatta gttttatttg
    10021 gagcagtaaa aggaagtagt tcaggattga aaagtttttt cgattttgca tctatattaa
    10081 tcacagtatt tgggtcattt ggagctttga tgattacatt tactattgac gatataaaac
    10141 ttataaaaga tgctctacaa tactcattca agacaatgaa tatatcgaaa ttagacttat
    10201 taaatcaatt taaaacactt tctaaaaaag caagaagaga aggactttta tctatagaaa
    10261 gtgatgtaat gaaaatacaa gacccattta tgaaaaaagg attagagtta tgtattgatg
    10321 gtcttgaaat aaatgaaata aggtctatac tagagctcga aatagattct gttgaagaaa
    10381 ccaataacag atattctaaa ctatttaaaa cttgggggac tttcgcacct gcatttggta
    10441 tgttgggaac tctaataggt ttaatacaaa tgttatccga ccttacatct ccagatttaa
    10501 tagcatctgg tatgggaaaa gcattaatta cgacatttta tgggtcttta cttgccaata
    10561 tcgctttgaa cccaattgca tataatatag atgagaagac tgaaaaagaa atttatgtaa
    10621 aggaaatgat gctggagggg ataataagca tacaatctgg agagagcagc atagtagttg
    10681 aggaacgttt agctacatac ctttcaaata atgagaagtt agaaattatg aaatccaata
    10741 aaaatacaga aagagcaatg agtaatggcg cgtaaaaaaa ataagaaaaa ggatgagata
    10801 aatccagatg catggttggc tacttatgca gatacgataa cactgattct tacatttttt
    10861 gtgttattgt atgctacatc agttgtagat atggaaaaat ttaaaaatat agcagatgcg
    10921 ttaaaaggtc agttttctgg gacaagtatg tttagtacag gttcaagtac aagtgagaaa
    10981 tctccaatag agagtgtttt agtggataaa aatgataagt caaatttaga acaggattta
    11041 aaagataaag ttaataattc taacttacaa aatagtgtaa cagtcaaaga tgatagtaga
    11101 gggattttac tagagctaga tgattcaatt ttatttgact ctgggatttc tgaattaaaa
    11161 gaagatagta aagccactct taataaagta tacgatatga taaagatgat gaaaaataag
    11221 atagttatag aaggccatac tgataatgta cctgtaaaat caagtacgca tgaatccaat
    11281 tgggatttat cttctagtag agcagtaagt gttgtaagat actttgtaga agaaaagggc
    11341 atggacccta aactattttc ggcaacagga tgtggagagt accaaccttt ggtatcaaat
    11401 gaaacagcaa agggaagagc tgagaataga agagttaata tacttataac tattgactag
    11461 gaggaagagg tttgttcaaa aataaaaaaa ttattataat tattttgata ctgattattt
    11521 tctcagcagg agcaggtttt tttatattag gagaaggtgg aaataaacaa attgacaaga
    11581 ttgcaggttt gtttattcca acagggaaag gcaaagatga agtaaagacc gaaaatcttg
    11641 acttagaaga gatggtattg aagctagctg atgaaggtgt aagatattta aaagtatcaa
    11701 taactgtatc ttatgattct tcatataaag atatagaaaa aaatacgcct ttaattaggg
    11761 ataatattat aaattgtttt atggcaaaaa gggcagatga ttttactgct gataatttaa
    11821 agaacataaa agaagaaatt aaaaatacat taaatataca actaggtgaa aatgtaattc
    11881 aaaatatata tttcacaaat atagtagtgc aataaaagga tggtaagaca tgatacttta
    11941 tttactaaaa atattaatat gtatcccaat aattttaata ttgatagtct tatctttaaa
    12001 aattagccaa ggaactttat taaaaaaata taatgataaa tatataaaaa tactagatat
    12061 tgtaaatata agtaaaaaca atagcataat aattttaaaa ataggtgaag aaggatgcat
    12121 tatggcatct tcttcttcta gcatgagtaa aataaaagat ttgaccaaag aagaaatatt
    12181 aagaatagaa aacgacatta aagaaagaaa ttttaaaatt caagatttta aaatggaaag
    12241 aattaaaaag aaatatgatt tcagtagata tattggaaaa tttacaaaaa aggaagataa
    12301 gtaaatggaa ctattatcaa aattaccttt ggctgatgta ccatatacaa gttcaatgca
    12361 attgttttta tttctaactg cattaatgtt tttaccattt gtaatgttca tgatgacaag
    12421 ctttgtcaga atagttataa gtttatcatt tttgaaatca gcattaggag cacagcaagc
    12481 aattccaagt caaattttgg tagggcttgc aatagtattg acaatattta taatgagacc
    12541 agtattaaat gagataaacg aaaaggcatt acaaccatat atgaaagaag aagttactat
    12601 ggaagaagct atgaaggaag cagaaggacc tattaaagaa tttttattaa agcaaaccag
    12661 acagacagat ttagatttat ttgtagagca agctggttta aaagaaaaga aattaactcg
    12721 tgaaaatata ccattatctg ttgtagttcc agcatttgct ataagtgaac taaaaactgc
    12781 ttttcaaata ggttttttaa tatatatacc atttttgata atagaccttg ttgtggcaag
    12841 tgttttgatg tctatgggta tgtttatgtt acctccagtt atgatatcat taccatttaa
    12901 attattatta tttgtaatgg tggatggatg gaacttgata gtaaaaacat tgatattggg
    12961 atttggatag gagaaaaata gtatgagtga atttatgata atgagtgttc ttaaaaatgg
    13021 catgtttaca ggagctatga ttgcagctcc agtgctaatt gtttctcttg tagtggggct
    13081 tttaataagt gtatttcaag ccacaactca aatccaagag caaactttga cttttgtacc
    13141 aaaactaata gcaattcttt tagtagtagc tattggtgga agctggatgt tacatactct
    13201 tattagcttt acttcggaga tattcaatat gatgtctctc ataactaaat aagtaggata
    13261 tatatgattt ttgtatttat tagaatagta gcattctttg gaacattaag gatactattt
    13321 ccagctggta cacctgcttt atttaagtcg ctctttgcaa tcattatatc aatcttgatt
    13381 tcaagtacta tgcaaattga atatgcaaca aatatagaca acattgtatt gtttacctta
    13441 tatggtataa atgagaccat aactgggatt atgcttggat atataaccaa tctatgtttt
    13501 tatagtatca gaatggctgg ttctatgatg gaccaacaga tgggattatc aatgattaat
    13561 atgtttgacc caaattcaat gactcagaca actttaatca ataatcttat gaactggaca
    13621 gcacttatga tattttttag catggatggt catcatgttt taattagagg cataaggtat
    13681 agttttgagt taattccaat agggaaatca ttcatagata ataatataga ttatataata
    13741 aacatatttg tgcagtgctt tttaactgga ttcaaaatag caatacctat tgtactttgt
    13801 ctgcttatgg cagattttat attagggctt atatcaagaa gtgtacctca actaaatgta
    13861 atgataattg gtatgccatt aaaaatactg gttggtattg cattatttat catatcaata
    13921 cctttaattg tcaatcaaat aagtcattta ttaagtcaaa taccaaagat gtatgaggga
    13981 acttttgcac tagctcctat gttttttatg ggttcaacag ataaaacaga agaagctact
    14041 ccaaagaaaa agggagaaca aagaaaaaaa ggtaatatag caaagagtaa agaattaccc
    14101 attgcaatga ctctacttgc attcacttta ttagtaccta cattattttc atatgtagtg
    14161 aatacactta aatcttctct taattatttt ttgagtctag atttttatat gaacataaat
    14221 tattcaagta tagagaaatt agttatagca ggattaatgg atttttttaa gatattttta
    14281 ccaatagcta ttccattctt agttttaggt atagtcgcaa acctatttca agtaggaata
    14341 ctgtttactg gtgaaacttt aaaacccaat ttatcaaaat taaatccaat tagtggattc
    14401 aaaaacatgt tttctatgag aagtttgtca accttaataa aagatacagc gattatatct
    14461 attttggctt acataggata tacattcttc caagataatt atttagatat attaaagtta
    14521 ggtaacatat acctgccaac tttaatgtac acagttaaag atttagtata ttcaatatta
    14581 agtaagattt gtgtagctat gatagttata gcagttgcag attatgttta tcaaagatac
    14641 agtcataaaa agcaacttag aatgacaaaa caagaagtta aagatgaata taaaaactca
    14701 gaaggagacc cagaaataaa agctaagata aaacaaaaac aaagacaaat ttcgtctcaa
    14761 agaaccatgc aagcagtacc aagtgctact gtaatagtaa ccaatcccac ccacttatct
    14821 atagcagtga gatatgaaaa agggaaagac caagctccag tagtggtggc aaaaggtgca
    14881 gattatttag cttttaaaat aagggaaatt gcaaagggaa atgacatacc tataatagaa
    14941 aataaaccta ttgctaggtt gttatataag caagtagaaa tagaccaaga aattccagag
    15001 gacatgtatc aagcttttgc agagatatta gtagcagtat ataaaatcaa aaatagatac
    15061 aaagtcccca aaaggtagga taagtaatga ataagtttaa tttaaaggaa aatatggacg
    15121 taatagtggc atttggtgtt gtagggattg ttcttatgat gatagtgccg ttacctacat
    15181 ttatattaga tattttactg gcaattaaca taagtttatc tgtgctaatt ttactaatga
    15241 cactatttac aacaaatgta cttgatttat ctatatttcc aacagtgtta cttgtgacaa
    15301 cactatttag attgggatta aatctttcat caactagatt gattttaaca cagggatatg
    15361 caggtgaagt tatagaggca tttggaagtt ttgttgtagg tggaaattac gtagtaggaa
    15421 taattatatt cttaattata ttaattgttc aatttgttgt tataaccaat ggttctggaa
    15481 gagtatctga agtaacagct agatttacgt tagatgccat gccaggtaag cagatgagta
    15541 tagatgcaga tttaaatgca ggagttatag atgacaaaac tgctagaaaa agaagaaaag
    15601 agcttcagca agaagcagat ttttatggct ctatggatgg agcaaataag tttgtaaagg
    15661 gagatgccat agcaggtctt atagtaacag caataaacat aataggtgga attgtaatag
    15721 gagctgtaat gctgaatatg actcttatgg gtgcagcaca gacatatgta agacttacta
    15781 taggggatgg tcttgtaagc cagatacctg ctctattaat atctacatca gcaggtataa
    15841 tcgtaacaag agcttctact gatgaaaact ttggtggatt agtaggtaaa cagttaacag
    15901 caataccaaa agcagtaatg atgactggct gtgttctaat cgtacttggt atgatgcctg
    15961 gattacctaa accagcattt ttttcactag gtataggtgc tatagcagca ggttactttt
    16021 taggaagaga aaagaaagat actttagaag acttggagtt tgaaaaacct gatatggtaa
    16081 atccagataa aaatgaagta gaagatgtaa caaacttaat aaatgtagaa tcaatagaag
    16141 tagaaattgg atatggttta atatctttag ctgatgaatc agcaggagga gatttacttc
    16201 agagaatagc atcaataaga agacaatgtg caatagacat gggtatagtc gtacaaccta
    16261 taagaataag agataattta cagttaaatc caaaccaata caatataaaa ataaaaggga
    16321 atgtagttgg tgggtatgag ataatgccta atatggtttt atgtatggat cctatgaatc
    16381 aaggatttag tatatttgga ataaagacaa ttgagcctac ttttggaata gaggcacttt
    16441 ggatagaaag tgacaaggta gaagatgcag agctaaaggg ttatacagtt gtagattcat
    16501 ccacaatact tataactcac ttactagata taataaaatc aaatgcacac gaattactgg
    16561 gaagacaaga agttaagact attatagatg cagcaagaga aaattatagt gctgtagtag
    16621 atgaattgat accagattta atgacacttg gtgaaattca aaaagtactt aaaaatctgt
    16681 taagagaaaa agtaaatata aaggatagag ttacaatact tgagacactt gcagaccagt
    16741 ctagaaatac aaaagatata gagcttctta ctgaatatgt aagaatagct ttggctagaa
    16801 gtatttgtaa taatttagtt gatgaagata aggcaattgt agtggctaca ttgtctccag
    16861 aaactgaaga attggtatct aataatttac aaaggtctgt aaatggaact tatccagcag
    16921 ttgacccaga aaatacaaat aaaatatttg agagtataca agaagtaatg aacaatgtat
    16981 atttcaatca taatatacca gtaatagtag tatcaccaaa gataagagct ccatttagaa
    17041 aattagttga aattgtatat cctaatttga ctgtattatc attaaatgaa atacctaacg
    17101 atattaaaat caaagcagaa ggtgtggtga gcatatatga tgacgaaaaa gtatacagct
    17161 aacacaattc aagatgctat gaatctagcc aaaatggaat tgggtgacaa tattacatta
    17221 atagataaaa aagaggtaag aaaatctgga ataagaggca ttttttcaaa gaaagatatt
    17281 gaattgacta ttggatggga aaagaaagat aatttagaac aaaaagattt aaaacgagag
    17341 atagaacaac taaagtcaat tataaataat atggggtttg ataataaaaa tgataatgat
    17401 atagataaaa tatgcaagaa tttactaaac ttagatttaa atcaagaaat tgtagaattt
    17461 ataaaagctg atttacaaga aatgaagttc aatggaattg atacaagtaa aaatttagta
    17521 gaaagtctaa agaaaaagat taaaatagaa aatcaagcaa taaatggtaa aattgcttta
    17581 gttggaccac caggagtagg taaaacgact acaatagcaa agttggctgc caaattagtt
    17641 tttgaggaaa ataaaaaagt aggagtaata actatagata catacaggat tggtgctgta
    17701 gaacagttaa agatatatac tgatataatg aatattcctt ttaaaggggt aataagccct
    17761 gatgagatgg aattggcact tgatgagatg aaagattgtg atgttgtatt aatagataca
    17821 acaggtagag gctataaaaa ctctatgcaa atattagaaa tcaaaaatct tatagataaa
    17881 gctgaaactg ataatataca tttagttttg aactgtacaa caagagaaag tgatacaaaa
    17941 gcaattatag attcatatag aaatgtgaat tttaaaagct taataattac aaagttagat
    18001 gaaacaataa catatggctc aatatttaac ataatgaatt atgcacaaaa accaatatca
    18061 tatattacaa caggacaaaa tgttcctgat gatattataa aacctaatga agataagatt
    18121 ataagattac tattaggagt tgaaagtata tgatagacca agctcaaatt ttgagaaaaa
    18181 tggcaatgga aaaaagaggt tctgatgaga ttatagtaga gaatgagaat atgcctaaga
    18241 taattacaat agcttctggt aaaggcggcg ttggaaagag taatctcgct acaaatttgt
    18301 ctatatgctt aaccaaactt gataaaaaag ttcttatatt agatgcagat ataggaatgt
    18361 ctaatataga tataataatg ggggtaaatg taaaagggac tataattgat gtaattaatg
    18421 gcgaaaaaaa tatagaagat ataatttcac agactaagta tggtgtaaat ataatatctg
    18481 gaggttctgc ccttaatcat atagaagact ttacagaagc tcaaagaaat aagtttatac
    18541 atagcataga acagattcac aatgtggatt ttataataat tgatacagga gctggtatga
    18601 gcaaaagcct attgtcattt atatactgta gtactgaatt tttcttaata acaactccag
    18661 aaccgacatc attgactgac gcatatagtt tattaaaagc tataagtaat tttggcataa
    18721 agaaaagtgc aaatataata atcaataggg taattgattt agaagaagcg aaatctacat
    18781 acaaaagaat aaaaatggtt gtggacaaat ttctaaacct taatctggaa ttgtatggat
    18841 atataataga tgacaaaaaa gtaggtgtat gtgtaaaaaa acagatacca ttcattttag
    18901 aatatcctac aagtattgca tcaaaatgta ttatagctat agcaaagaga atggtaagtc
    18961 agtcaagaga agatattgtt gataataaaa gttttctaag aaagatgttt agtatattta
    19021 aaagctaagg aggcgtagtt aatgaataga gaagaattaa taaaagagaa tatgcctctt
    19081 gtaaagagta tagcaagaaa attttttata ccagggaaag gttttgaata tcaagactta
    19141 gtaaatagtg gagtcattgg attgattgat gcaataaata aatttgatac tgaaaaagga
    19201 gcaaagtttt ctagttactc ttatataaag ataaaatctg ctatattaga tgaaattaga
    19261 aatcaaagtc caatttctaa acataatcta actaaagtaa ataagtataa tagagtggta
    19321 gaaaagttgc aatctaaatt attaagagag ccaacttcat atgaaattgc aaaagaatta
    19381 aaggtttcag aaaaagaact tcatgatatc gaaagtaata tagatatgtt aaatattgta
    19441 tcattaaact atgtaatctt tgaagataca aatgaaactg tacaagatgt aataagtgat
    19501 agagaagagg aagctccaga aaatataata gaagaagaag aaaagttaga gattctatcc
    19561 aaagcaatta gtaatttaaa tgaaagagaa aaattaatac tttcactgta ctattatgaa
    19621 gatttaaatc taaaggagat agggaaagtg ctaggtgttt cagaatcaag agtttcacaa
    19681 ctccacagaa aatcaataag aaacttaaga aacaagataa aagaacttaa atattctata
    19741 tagatggtga ttgataagat gatacaaatt atattaatag tagtgtctat tttaataata
    19801 gtaactatag ttataaattt acagaaggaa tcaaaaaata aagataacag atactttgat
    19861 aaaatatttg agcaagaata tgaagcaaat gatagattaa taattgcaga aaaaagaaga
    19921 ttctttttag acaaagtact tgcagaaaaa agaattaata gtcatataaa agtttatgaa
    19981 aattataacc taataaaggc taatgaagaa agaaaggaaa acatatttat agaatcaaaa
    20041 aaggaagtaa gacaagaaaa tgagttatct cttaaagtga aacatcttat aagttcaggt
    20101 tatgatgatg tggaaatatg taagatgcta gatattggaa agggggaact gttattaata
    20161 aggagttgtt acaaaatata aggatattat tatgtgataa aaaagtattc ttaggaatag
    20221 gtattggtat attaatatca actttatgta taatgctttt tagtaataat gatatgagta
    20281 aggcagagat agaaaaaaag gccagagcgt taggcatgaa atatacaagt gagatgaaag
    20341 ttttagaata gatgatactg tttagacatt tacaaaaaag gaggtcataa tgtgataaga
    20401 ggattatata cagcagtttc tgctatgata actaatcaac aaaagcaaaa tgttgttgtc
    20461 aataacctag ctaatatgga tacaaatgga tataaaagta aacaactttt gactaaaagt
    20521 tttgatgaat taaagttgga gggttacaat aactacgcaa atggaactaa acaaaagcag
    20581 attataggcg atataagtcc aggtatttct atggatgaaa ctatcacaaa ttttaatcaa
    20641 ggacctataa aaactactga taataaaatg gatgtagcta ttcaaggtaa gggatttttt
    20701 ctagttagtg atgcagctgg aaatcaattt tacactagaa atgggaactt cagaacagac
    20761 aatcaaggtg accttataac aagtgaaggg tattatgtac ttgggacgaa tactgctact
    20821 ggtgctgtag gtcatataaa tgtaggaaat caaaaatttg aagtggcaaa agataataca
    20881 atatcactag acggaaatgc tatgtataaa tttaatattg tagattttaa taactacaat
    20941 aacttaaaaa aagaaggaga taacttatat tctggaggag gagctatgaa agtaaataat
    21001 gcacttacaa tacaaagtgc gatagagtcc tctaatgtag atatggtatc tgaaattaat
    21061 aatatgatga caatatcaag agaatatgag gcaaatcaaa agataattca ggctatggat
    21121 tctaaattag caaaaatagc aagtgagatt ggttcagtaa gataggtaat aggaggtgaa
    21181 tttttatgta cacaatgttt tatactagta aaacagcttt atcagcaaat caaagtaaac
    21241 tagatataat atctaacaat atagcaaatt ctgattcaac aggatataaa aaaataaata
    21301 tggaatattc tgatttagtg gatgaagtac taaatagacc atcataccct acaaatggta
    21361 aagatatatc gactggaaca ggagctaagg caacagctcc catgagaaat tatgaacaag
    21421 gtgcattggc tcctacagat agtaagagta atttggcgat agatggagaa ggattcttta
    21481 gagtgataag aaaagatggt acatatgcat atacaagaaa tggtggattt aatgtagatg
    21541 ctttaggtaa gattgtagat gataatggaa atatattaga tgtccaattt gatgcaggat
    21601 ataactataa taatacaaat atagatagta caaacctgac agtttcaaga aatggagagc
    21661 tattcgtaga taataaaaaa ataggaaaaa ttaacttata tcaacctata ggaactcaaa
    21721 attttatatc tgaaggagat agtttatttg tcgcaactga tgcagcacag attaaacaag
    21781 ttgagaaagt cgatatagtt caaggctata gagagaggtc aaatgtttct ttacaagaag
    21841 aatttgttga cttaatagcc actcaaagag catttcaaat gaactcaaag ggaataaaga
    21901 cagcagatga aatgtggcaa atagcgaata atttaagagc taaataatta tgtaaggaga
    21961 ggaatattca tgaatgatat gaaagagtac gattttggca aacctcagag ttattcaaga
    22021 gaaaatttaa cttgtttaaa ttttttatta gctgaatttt gtaaaaaata taaaaactat
    22081 ataatttatg aacttaagtg taattctagt atggttgttg atagtataga ccaagtaaat
    22141 tatcagactt ttttagatag agtaacttct tcatgcgtag tagtacaaaa tgcaatggaa
    22201 cctgttatga aaaacttttc ttttagaata gatagaagtg tagctgatat gtggattgat
    22261 ataacttctg gaggaactgg agttgtaaag gataatgata gagagcttac agaacttgat
    22321 aaaaaagtgc ttttacacct tatggatgat ttagtaagaa atatgcactt atttgagggt
    22381 tttgaaaata tacaagtatt ggatacacat acacatatta atttgccaca attatgttct
    22441 ccaactgcac cagtatgcgt tgtagattta aaagtgctaa atgataatga gtgtattgga
    22501 agtgtttctc tttgttttcc atacaatggt ttagaggctc tgttagaaag tatatctgtt
    22561 atagaatttt ttgataatga tgtaggagat gattcagagg aatttaccca aaaaatctat
    22621 aatagtgtat ctaatataga attatcagtt attgcagaga taggaaaagt atcaattaat
    22681 gttgaggatt tacttaaact agaagttgga gatgtaatag taacaaataa aaaaataaat
    22741 gattatatag atatatttgt agaaaattca aaatcataca cagcaacacc aggatttata
    22801 tcaagtaaaa aaggtgtaaa aataaatgat gctgttggaa aagaggtgta gttatggaca
    22861 atagtaatct tatttcagat gaagaagcaa agatgttatt aaatgataaa gttgaaagtg
    22921 aagttgatgg agatgatgag ttagccttag atgtctctga agttaatcga aataatatac
    22981 aaaggatact tgaccttaag ttagaattat ctgtagttat aggaagaact aagatgactc
    23041 taagagatat tttaaattta cataaaggtt ctcttattga actggatact ttagcagacc
    23101 aagatgtgga aatactaata gataataagg ttttggctta tggaaaagta gtggtggtag
    23161 atttaaattt tggtgtaaag ataacaagta tagtaagtga agaagacatg gtaaaatctc
    23221 ttgtttagag ataacatcaa ttaatactta aggcatgagg tggtacttat tttaaactta
    23281 aatgatataa aaaaagatat actaaaactc aataaaaaag actcatgttc tctatataat
    23341 gaatctatta ataatataaa taataattgt atatcaactg gattaaaatt tttaaaacaa
    23401 gcaagagatt taaacccaga tgatgttgat atattaaatc tcacaggtct tgtaaactta
    23461 ctaaaatgta attttgatga tgctgtagaa agtttctata agagttcact ttgtgaaaaa
    23521 actgctctgt gtgaaaagta tataaacatg cttacatctg aggagttttt aattttcttt
    23581 gaaaagtaca atcaacttat aaggttaata aataaaggaa tgtataaaga agctatacaa
    23641 gggtttaaac tcataactga ccaatactgt gatttaatag aaccttatga gttgcttgcc
    23701 ttactgtatg acaaggaaga agaatatata aaatttgatg aatgtttaga agtattgaag
    23761 attattgata aggaaaatta tttattaaat caagaaaata acacattaga tatgtataat
    23821 agtgctaata tacaaactaa aagtaatata aaagtagatg attataagaa tgagttctta
    23881 cataaaagta gtagtaacca taaaattaat gattataatg atgtaactaa agaaaagagt
    23941 tcaagcaaaa accagaaaag ttcagattct aataagaaaa aaagtattaa aaaaaataag
    24001 tacctatata tagccataat attaggaata ttattagtag gacaaagtat atataattct
    24061 tataagatga ataatttaac tgataaaata tctaaaaata atgaaactaa aaatgaagag
    24121 tcaatagatt ctaacttgac taagaaagaa aataatatag aagaaaatga agatatgagt
    24181 aaggcttcta atataaataa gagtaataaa aacattaata aagaggatga tgtaaaatct
    24241 aaaaaaaata ctgtagaaaa tgaagatgat aaagattctg acttatttac agaggatgaa
    24301 ttgatgtcta aggcgaatac tttaaaatca gaaaagaaaa ctaaatcttc tatacaacta
    24361 tataagaaag ttgcagatat aggtgaaaat aaagggaata catctgaagc aacttatcaa
    24421 gttgctattc tcagtgaaaa gttaaaagac tataaaactg ctgaagaata ttataaaatg
    24481 tatgtagaaa attactcaga aaaagatgct tattttgatg aatcttatta taatttaggt
    24541 atgatgtact ataacaatgg tgatttaaaa aattctaaat tgacattaaa gaagttggtt
    24601 aataaggtac caaatagtat gtataataat tcaaaagtaa aagaaatttt aaaagaagaa
    24661 tagttaaatt agataagaaa aataaattat tttattttaa aataatatga ttataatata
    24721 ttgacatacc attttaaaaa atttaaaata ttaattataa aatgaggagg gataaaaaat
    24781 ggaatttgaa aaagggagta tttcaattca tacagaaaat atttttccta taattaaaaa
    24841 atggttatac tctgataaag acatatttat aagagagctt ataagtaatg gatgtgatgc
    24901 agtaagtaaa cataaaagac ttgtatcact aggagaaata tcagaaaata agtcatcaga
    24961 ttataaaatt acagtatctg taaataaagg agaaggtaca cttaaattta ttgacaatgg
    25021 aattggtatg actgaagaag agataaaaaa atacataaat caagttgctt tttcaggtgc
    25081 tgaagatttc tttaataaat ataaggataa aatggaagag tcaaatgata taataggtca
    25141 ttttggatta ggattttatt ctgcatttat ggtgtctaaa aaggtacaaa tagatacact
    25201 ttcatataca gaaggagcga ctcctgtaag atggatatct gaaggtggta cagaatacga
    25261 aatatctgaa tcagatgcta gaaatgatag aggaactact ataacactat ttattgatga
    25321 tgatagtaaa gaatttttag atgaatttac tgtaagagga ataataaata aatactgttc
    25381 tttcttacca gtagaaatat atttagaaga tgttgaaaga ttagaaagag aagctaaaga
    25441 agcagaagaa aaagctaaaa aacaaaagga agatggaaaa gaagagattg tagatgcaaa
    25501 agtaattgag cctttaaacg acactaatcc tctatggtta aaatctccaa aagactgtac
    25561 tgatgaggag tataaagagt tttatagaaa ggtattcaat gtatttgatg aacctttatt
    25621 ttggatacat ttaaatgtag attatccttt caatttaaag ggtatacttt acttccctaa
    25681 attaaaaaat gagtttgaac tgactgaagg aaaagtaaaa ttatacaaca atcaagtgtt
    25741 tgtggctgac aatataaaag aagttatacc agaattttta cttttattaa aaggagttat
    25801 agactgccca gacttaccat taaatgtatc aagaagtttc ttacaaaatg acagggatgt
    25861 aagcaaaatt tctaaacata taattaaaaa agtagctgat aagttaaaat ctctttgtaa
    25921 aaatgaaaga gaagaataca ataagttttg ggatgatata caaatattta ttaaatatgg
    25981 ttgcttaaaa gatgaaagtt tctatgagaa ggtaaaagaa tgtatattat tcaaaactat
    26041 tgatgatgag tatataacat tacaagatta tttagaaaag tgtaaggaca aacatgaaaa
    26101 taaggtattt tatgtaagtg ataaagaaca gcaatctcaa tacattaaac tatttaaaga
    26161 atacgactta agtgctgttg ttttaaactc atcaatagat actcatttta tttcatttat
    26221 ggaatataaa gagaatggag ttaagtttaa tagaatagat gcagaccttt ctgatgtatt
    26281 aaaagataaa aatgaaaata aagatagtga agaaaacaaa gaagagatag ctaagataga
    26341 aggtctgttt aaagaagctg ttggagaaag agtgaagaat tattctgtag aaggattgaa
    26401 aaatgaagac actccagcta tggtgttagt atcagaacaa tctattagaa tggcagaaat
    26461 gcagtcaaga tttgctggaa tggatttagg aatgaatttt gaagaagaaa aaactcttgt
    26521 aataaatgag aacagtccaa taatcaaaaa attggtttct cttaaagatg atgaggaaaa
    26581 gaaagataag attacgctta tttgtaacca gatagcagat ttagctttac tttctaataa
    26641 agaattaaag ccagatgagt tagattcatt tgtacaaaga agtaataagc ttatgagtct
    26701 tttgatagaa ttataagatt gaatttgaat acattgaagc aaatttataa aaagtattca
    26761 atatcagtga taagaaagaa gtgtctcaaa atgaactttt cagttcatga ggcgcttttt
    26821 ttatgtgaaa ttaaatttat tttaatcatt tcaacaatga aaaatatatt tatctctatt
    26881 ttgagacaga ccgttcttta tttttttatc tttggttaat ttttaaatat ttaagtaggt
    26941 tctaataaaa aactctattt agttaaatat agttaacttg atatataata agataataca
    27001 tataattaag taaaagattg ttttttagtt tatgtttaaa tacataatta cactttgtta
    27061 aaaacataaa attattacta aagtagaaat aggaggtttt agcatgaatt ttaattataa
    27121 tttgccagta aatatcttat ttgggagcgg cagaattaat gatgtgggaa aagaagtatc
    27181 taaatatggc aaaaaagtat tgatagtaac aggtaaaaat agtacaaaga aaactggatt
    27241 acttgataaa acaatagatt tactaaaaga ctctaaaata gaatatgaag tttttgatag
    27301 agtagaacaa aatcctctta taactactat atattcagga gtagaaatta taaaatcaac
    27361 tggatgtgat tgtgttttag gtcttggtgg tggaagcatt atggatgctg ccaagagtat
    27421 agctttttct tataaaaacc caggagattt aaatgattat atatttggaa ttagacaagg
    27481 tgaagaagct ttacctataa tcttagttcc aacaacatca ggtacaggta gtgaaggaaa
    27541 ttgttttgca gtacttacaa attcagaaac taaagataaa aaatctataa agaagaatag
    27601 tatgtatgca aaagcatcaa taattgaccc agaacttatg gttacaatgc caaaacatat
    27661 aattgcatca gttggatttg atgcacttgc ccataatatg gaagcatatc tttctaatgg
    27721 aagaaaccct cttgcagatg tacaagctat ttatgggatt gaacttatat cagaaaacct
    27781 aataaaggta tataatgatg ttaatgattt agaagcatgg gaaaaaataa cacttgcaag
    27841 tactattgga ggaatgacga ttggtacagc gggtacagcc ttgccacatg gaatggagca
    27901 tcctgtaagt ggtcttagag atgtaatgca tggaaaagga cttgcagctt tgactcctac
    27961 tattatagaa agttcatggg atagtgatat tgaaagattt ggtaatattt caaaggtatt
    28021 aggaggaact tgtgcagaag attgttcaga tgcaattaga aatttcctta aaaaaataga
    28081 tttagatata aagctaagtg atttaggtat tgaaaaatca gatatagatt ggttaactga
    28141 taattgtatg aaaatatcag ttgcaaatat taagagacat ccaaagtatt ttaataagga
    28201 acaaataaag gaaatgtacc ataagtcttt ataatttgac tttacatatt tagttttata
    28261 taaaaattat aaattaataa taaaaaatta taagtaatta atagtaaaaa aattgtgtat
    28321 agaagttata tatataataa atttgtctta agcttttatt ttactttcta ataaataaag
    28381 gagtttaaaa aagggaagat taattaagta atattttata aaattcttcg atttaaaaac
    28441 tttaagtaga ggtgaaataa atgtttaatc ccaaaagaat aatattcgaa aaaggaactt
    28501 tagacactga tgtgggtaaa aaaatataca ataaatttag agataataaa gatgtagaga
    28561 taattaatat atcatcaaat aggattaaag aacatattcc aggtgaaaat ctatatgaac
    28621 aatatagaag tgggaagcag actatggtag ttgggattag aaaaagtctg aagtttcaaa
    28681 catgtaaacc ttctgctaat tatcaactac cacttgtcag tggatgtatg ggaagatgtg
    28741 agtattgtta tttgaacaca caattaggtg ataaaccatt tataagggtg tttgtaaatg
    28801 tagatgaaat acttgaacag acaaaaaaat atattgaaga tagaaagcca caggtaacca
    28861 tatttgaagg ggcagctaca tcagacccag ttccagtaga gccatatact aattctttga
    28921 agaaaacaat agagtttttt ggaagagagg aaaaaggaag atttagattt gttactaaat
    28981 acagtgatgt ggatagctta ttggatgctg aacataataa tcatacagaa atacgattta
    29041 gtatcaatac tcctagaatt ataaatgaac atgagcatta tacagcctct gcaaataaaa
    29101 gaatagagtc agctgtaaaa cttgctaggg ctggttatca gattggtttc ataatagcac
    29161 ctgtgttttt atatgaaggt tggaaagaag agtataaaaa tctgattata agtataaaag
    29221 aagctttacc aaaggatttt gataaaaaaa ttatatttga agttatatct catagatata
    29281 caactaaagc aaaaaataga atactagaga tttatccaga tacactattg ccaatggaaa
    29341 atgaagatag aaagtttaaa tacggtcaat ttggatatgg taagtacgtg tatgataaag
    29401 aacaattaga tgatatgaaa gagttctttc ttaaggaaat aaatggagta tttaaaaata
    29461 gtttaataaa atatataata tagcaaatct tacctaaaga tttgctatat tttattttta
    29521 tatattttat gtttataata aagcaatgag atttagcatt atcatataag aaaattaaaa
    29581 agggcactat ctatcaagaa cattttttct agttttgata ctataaagga taagagtaac
    29641 aaaaatatca ggaggagtta tagtatgcat gcatgggagt ctattcaaat tacattggat
    29701 ttaatagaag caaatttatc agaagaaata tcaattaatg aattagcaaa taaagcaaat
    29761 ttatcaccat tttactatca aagactattt aaaagattgg taaataagac tgtaatggag
    29821 tatataaagc ttcgtcgtct tgcaagagct tctgaatact tagcagaaca taagaatcgt
    29881 atacttgatg tagctttaaa ttttggattt gctagtcatg agacatttac acgttccttt
    29941 aaaaaagcat atggattaac tccagaaaaa tatagagcaa atccagtaaa actcaatcat
    30001 tttattaagc cagaattaat tttaaattat gctatggttg atgaaggtgt tccactgatt
    30061 gcagatgata tagtgattga agtcaatcgt aagacattga gtaatccaag gacatttgtt
    30121 ggaatagaaa tagaagtacc tatttgccag ttggtgggcg gtgaaacaac tggaattgca
    30181 atagtagagg aattatggat gaaacttgga agtcaaagac ataatatacc aaatcaaatt
    30241 ccaggtggaa atgaatttgc tgctctttat atgggaaatg caaaagaagg aaattgtatg
    30301 tatatggcag gtgtagaggt agagtcaggt acatcagtag aaggatatag tacttttgag
    30361 ttgccagcta aagaatattt agtatgtgga tttgaggcag aaaactttaa tgagttagtt
    30421 aattcagctg tttttaaagc agataaattt atggaaagat ggatgaagaa acataattta
    30481 acaactactg attttgcaat tgagatgtat taccccacta cacctgaagc agcatatctg
    30541 gaacattgga ttgttccggt tcctattgaa caatagaaag gatgatgaat atgaattggc
    30601 aagatgcgtt ttttcaagat actaaaccta catttgagca aattaatgaa tttattaata
    30661 atccattatg ggacaagtta aataaaactt tggtttctac ttataatgta gaacctaagc
    30721 ttgaatacag taaatgttca atgcaaagag gttggaatgt aaaatataaa aaaagaggta
    30781 aatcactatg tactttatat ccacaagaag gttattttaa agctttggtt attgtaagtg
    30841 aaagcaatag agtagaggtt gatttattta ttaatacttg ttgtgattat atcaaaaaaa
    30901 tatataatga ggtaaacttt tttaatggaa gtaaatggct aatgattcaa gtagatagtt
    30961 tattggtatt aaacgatatg cttgaactaa ttaaatttag agcttaacat atagaacagg
    31021 atgaatatat aagtcatcct gtttttatat tcaatcagat aaattaatat atagtctata
    31081 atatgaataa tttagtaaat ttaaatttac tttatctttc tacattcttt gcaactaagt
    31141 ccacatgtgt ttttttcttg catattagta gcaccccaat tagcaaattg ttgtaaaata
    31201 ggcacaatac ttttaccttt acttgttaat gtatattcaa cttttggagg aatttcatta
    31261 tattgtttac gatgaacaat accagtagac tctaaatctt ttaatgattg agctagcata
    31321 gtatttgtaa tgccatccaa ttttcttttt atgctactat atctaattgg attttcaact
    31381 gctaacatac atataatagg taatttccac ttaccaccga caatgtctaa tgcataacgg
    31441 attggacagg ttaattcttc aacgttttta gttatatttt tttcagtatt tatactcatt
    31501 ttaattactc cttagttata gtagtatctt ttttatactt tatcagaaaa aactgcatac
    31561 ttgttttttc tgtattttat attaaaatta tatcaaagga taatccttaa tacaagtatt
    31621 taaaaggggt gtaagaatta tgaaagcatt agaatttttg aacaaggcag gagtttatta
    31681 tttagcaaca gttgatgaga acaatcaagc acatgtgcgt cctttaggat ttgttatgga
    31741 atacaatggt aaacttacat tttgcacatc taatcaaaag gatatgttta agcaacttat
    31801 ttttaatcca aaggttgaac tttgttgtat agaccaaaac cttaatactc tacgtatttt
    31861 aggtgaagca gtatttgtta catcaaaaga aacacaagct aaggcacttg aaataatgcc
    31921 aagtttaggt cagatgtact ctgtaggaga tggtaagttt gaaatattct ctattgataa
    31981 ggcaaaagtt agttgttgtt caatgagtgg taaaaagatt gatgtagagc tttaattata
    32041 attgaatcga catccatagc gaaaattaag aaaacgttat tactgaaata ttgatagatt
    32101 taatttaaat gcaataaaaa gatttttaac taatgaatat gtaaaaattt ttagttatta
    32161 gatgtgtatt tcaataatga tatactattt tgaataatta catactagaa ataaga
//
LOCUS       DAMJWC010000045        31975 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMJWC010000045 DAMJWC010000000
VERSION     DAMJWC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31975
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.045"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(65..469)
                     /locus_tag="PC503_002415"
     CDS             complement(65..469)
                     /locus_tag="PC503_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2528382.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(661..1848)
                     /locus_tag="PC503_002416"
     CDS             complement(661..1848)
                     /locus_tag="PC503_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF2528383.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1880..2305)
                     /locus_tag="PC503_002417"
     CDS             complement(1880..2305)
                     /locus_tag="PC503_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528384.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIG
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVHKEE"
     gene            2783..3532
                     /locus_tag="PC503_002418"
     CDS             2783..3532
                     /locus_tag="PC503_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2528385.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFEIITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(3708..4073)
                     /locus_tag="PC503_002419"
     CDS             complement(3708..4073)
                     /locus_tag="PC503_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2528386.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWRSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(4089..4865)
                     /locus_tag="PC503_002420"
     CDS             complement(4089..4865)
                     /locus_tag="PC503_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2528387.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(5276..6703)
                     /gene="ascB"
                     /locus_tag="PC503_002421"
     CDS             complement(5276..6703)
                     /gene="ascB"
                     /locus_tag="PC503_002421"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2528388.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFVVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(6764..8692)
                     /locus_tag="PC503_002422"
     CDS             complement(6764..8692)
                     /locus_tag="PC503_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2528389.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(8837..9679)
                     /locus_tag="PC503_002423"
     CDS             complement(8837..9679)
                     /locus_tag="PC503_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2528390.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(10026..11396)
                     /locus_tag="PC503_002424"
     CDS             complement(10026..11396)
                     /locus_tag="PC503_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2528391.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIENFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(11435..12106)
                     /gene="pgmB"
                     /locus_tag="PC503_002425"
     CDS             complement(11435..12106)
                     /gene="pgmB"
                     /locus_tag="PC503_002425"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2528392.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     INREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGVKDEFDCIVNPSLLKRGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(12108..14498)
                     /locus_tag="PC503_002426"
     CDS             complement(12108..14498)
                     /locus_tag="PC503_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2528393.1"
                     /translation="MSLIFTTKDQLVELGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGVRTYFEATNDEEFMMQNGLEILIETSRFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVFVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(14524..15972)
                     /locus_tag="PC503_002427"
     CDS             complement(14524..15972)
                     /locus_tag="PC503_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2528394.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKN
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(16377..17264)
                     /locus_tag="PC503_002428"
     CDS             complement(16377..17264)
                     /locus_tag="PC503_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2528395.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(17364..17813)
                     /locus_tag="PC503_002429"
     CDS             complement(17364..17813)
                     /locus_tag="PC503_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2528396.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(17803..19710)
                     /locus_tag="PC503_002430"
     CDS             complement(17803..19710)
                     /locus_tag="PC503_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2528397.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(19978..21873)
                     /locus_tag="PC503_002431"
     CDS             complement(19978..21873)
                     /locus_tag="PC503_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2528398.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(21909..22787)
                     /locus_tag="PC503_002432"
     CDS             complement(21909..22787)
                     /locus_tag="PC503_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF2528399.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(23330..23500)
                     /locus_tag="PC503_002433"
     CDS             complement(23330..23500)
                     /locus_tag="PC503_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528400.1"
                     /translation="MSALLYGVCNKSISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(23897..24109)
                     /locus_tag="PC503_002434"
     CDS             complement(23897..24109)
                     /locus_tag="PC503_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528401.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(24110..24526)
                     /locus_tag="PC503_002435"
     CDS             complement(24110..24526)
                     /locus_tag="PC503_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528402.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(24594..25007)
                     /locus_tag="PC503_002436"
     CDS             complement(24594..25007)
                     /locus_tag="PC503_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528403.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(25840..26469)
                     /locus_tag="PC503_002437"
     CDS             complement(25840..26469)
                     /locus_tag="PC503_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF2528404.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALRQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(26548..27510)
                     /locus_tag="PC503_002438"
     CDS             complement(26548..27510)
                     /locus_tag="PC503_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2528405.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVIEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(28272..31814)
                     /locus_tag="PC503_002439"
     CDS             complement(28272..31814)
                     /locus_tag="PC503_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528406.1"
                     /translation="MQQKCKKKALSMILSISMGLGPVASFNASNTFADTIEESTNAGN
                     AEGGTNAGNAEGDTNAGDAEGDTNAGDAEGDTNAGDAEGDTNAGNAEGDTNAGNAEGD
                     TNAGDAEGDTNAGNAEGDTNAGDAEGDTNAGDAEGDANAVVVEEEATAEEPTSVGDFK
                     ISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIK
                     TASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNR
                     DIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGN
                     TESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGIITAKGAYHGA
                     GIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGT
                     NRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDL
                     EKKTKVFMNKISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSD
                     QFKGSEVSVNLVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKR
                     YDGLPFEEDVEKSFLDWIFKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDINL
                     GSDDLTKQVDAGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEES
                     KAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGS
                     ESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDV
                     DGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPD
                     KNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDN
                     GGNSKPDSGNGGNSKPDSGNGGNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDP
                     DNGGNSKPDPDNGGNSKPDPDNGGNSKPDIDTDGDGKPNINIDTDGDGKPDINIDTDG
                     DGKPDINIDTDGDGKPDINIDIDGDGKPDINIDTDGNGKPDINIDTDESLDSNVGQNV
                     QTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
BASE COUNT        10263 a         5680 c         3326 g        12706 t
ORIGIN      
        1 atttaaacgc tctagtgata tttttaaata aattttaata aaaattattc tattttgtca
       61 taaatcattt atctggctta tatttaagat atattggtgg atactttaca ctttttaatt
      121 cctcattact tcttaaaagt ttattattat tttccatatc ataaatttgt aacattactt
      181 tatttacata tagagcataa taattatcac tataaaaata ttgatactca tatcgagggt
      241 catctttgta atacactttg tatagtattc cttcgtaact tgccttcttg gctttttctt
      301 ttgtaatact ttttatatta tcttttgaaa tatcttgttt taccatatac ttatcaatat
      361 atgtttcagc atctttccat ggtttaatgc agtttttata tacaacaaac cctgttacac
      421 ttataatacc tataattaat actataaaaa taactttata ttttttcata ttaatcctcc
      481 ttcatttatt atttaaaact cgatataatg cactaaaaaa aggatgttat cttttttatt
      541 aaaatataac atccctcata tttagcatca atatatatgc cccaactggt aggttaaaag
      601 accccactgt cagtactttg attaaattac atgtatgtat atatattttt aacaaatcta
      661 ttatatgtca acttgtctac tattacatat aatctgtaat attacatctg ctgctttttt
      721 tgagcctcct gcattataaa agctttttga tagtttagtt gcattttctt tatattcatt
      781 gtcatttata acttgaaata ctgctttttt aatactttct gatttatcct cttttaacat
      841 aattcctgct cccaaatgaa caactctctt agctaccatt ctctgctccg aatgttgagg
      901 aaataatacc ataggtactc cataatataa actttcatta acactattca tcccagaatg
      961 agtaacaaac acatcagttt tttgaagtat agcaatctgt tcaacactat ttttaacctc
     1021 aaaattattt ggtatatttc ctaaactttt aatatcagta cttctaccaa cagacataat
     1081 cacatcaaca tcagaatctt taaatgcatt tatacagttt ttataaaagc taacattttt
     1141 attattaatt gtaccaagcg aaatatatat tagctttctt tttctctctt taggttcaat
     1201 aatcaacttt gatactgatg gacctacaaa tgaatactta ctagagaagg tttctaccat
     1261 tggttgaaat tcttttgatg tatatacaat ggtatccgta tcattatcat tagaaactat
     1321 agaaataaaa ttttttactt catacccttt tctttgtaaa agctttattt ttttattaat
     1381 gcgtcttaca ccaaaaatca tacgtataat ttctataaag ttttgtttca tcaactttgc
     1441 tgtatgttta ttaaatgcaa aagttgttgt agagcataca tatggaatat taagtttttg
     1501 tgcaaataac tttccccaaa aacttaatga atctgataca atgcaatctg gattaaaatc
     1561 tttaagttct ctacaaactt tttcatctaa agaaatagta gtatctacta tcatctcaat
     1621 taatccagga aaatccttac caattttttt ctcatctcca gggagtaatt ctggaaggta
     1681 tttatcacaa caaataaatt ttgctccagc accttcaatt ttatctttaa attcattaaa
     1741 agaataatac aatacctcat ttcctctatc cactaattca cgaactactt caatagtagg
     1801 attagtatga ccatatgcag gaatgctaaa aaatactatt ttactcatat ttcatacctc
     1861 cttttataat ttttttaaat cattcttctt tatgtactac tcccacatga cctataaaat
     1921 ttatcaaatc acgttgatga acaattccta atcctctttc ctcatctcca agtaccaata
     1981 atttatctcc tgcatttata ttaaatactt ctcttgcttc ttttggaatg acaatctgac
     2041 cacgttcacc aactacaact gctccaaaga aaaactttcc tttaggaggt actataatac
     2101 ctgttttttc ttccgaatga ttaactaagt catctagttt aacattgtac aattttgcaa
     2161 gtttaatgca actacctata tcaggaatag attctccact ttcccatttt gctattgatt
     2221 gtctagaaac attaagtttt tcagctaatt cttcttgtgt atactgattg atttttctta
     2281 gactttttaa attctcatta atcatatttt tcatacctcc tatgtttata atattggatt
     2341 tattatttaa attctatcaa ctaatcttaa cattcatata tatatttata tacttttatt
     2401 atataaattt attgttcagg taacatattt ccttaagtta tcgtaaacaa aaaaacaaac
     2461 acaaatctac taactgttgt taaagtattt aagttaaggt catttacatt atcaaatatt
     2521 tctacacctt caaaataacc tttatattta taatctttca taagcaaatt attatccctt
     2581 ctcatataca agtccagttg atgtcttgtt gctaaattta atggtaatca aattctttac
     2641 caataagtat aaaaattact aatgtgttat aattttctta actactaaat tttacataca
     2701 tttgaataga atatatcaat aaattactat aataaataaa aaattaagag ttaaaataaa
     2761 aaatagttag ggagatatta ttatgatttt atattttagc ggaactggta atagccgata
     2821 tgtggctcgt aaaattgcac aagaattaaa tgatgaactg atatcactaa atcaacttat
     2881 aaaagaggaa aaaacagatg aattaatatc aacagataaa ccattcatat ttgtatgtcc
     2941 tacttatgca tggagattgc caatagtggt tacggatttt ataaaagaaa caaaatttct
     3001 aggaagcaac agagtttact ttgtaatgac ttgtggtgga gatacagcaa aatccataaa
     3061 ctatattcaa aaactatgta aatacaagga atggcaatta aaaggtatgg cagaaattaa
     3121 aatgccagag aattatatag ctttattttc tacaacagac aaagaaacat caaaacaaat
     3181 gattaaagaa gcagataaac aaatatatag gattatttct gatatacgaa atgaaaatga
     3241 atttgaaatt attactccta gtggcttagg aggtacaatt aaaagtggta taataaatac
     3301 agttttttat aagacaatta ttagtgccaa aggatttcat tatactgata aatgcattgg
     3361 ctgtggaaaa tgtgtagagc tatgtccttt aaataatatt aatttaaaaa acaaaaaacc
     3421 agtttggaaa aataactgta ctcattgtat ggcatgtatt tgtggttgcc ccactgaagc
     3481 tattgagtat aaaaataaaa ctcaaaacag agaaagatac tatttagaat aatatattct
     3541 taatatttaa accattataa aatgaactat acccattgtt ttatacagtt ttacatattt
     3601 taactgtctc ctaagatggg tatagttcaa aagatagtgt ctcaaagtga actttttagt
     3661 tctttttagt tcctaaatca atctttttgt attaaatcaa gtataattta atcacctttt
     3721 cttatatcat tttcactaat atgttgtatt ccaacaaata taagatttat tagctctgtt
     3781 agtgacctcc attgtgattt ttttgaatca agataataat aattttttgt tccttctcta
     3841 cgcaaattaa caatctctgc ttcttttaat atcttaagat gatgagatac agcaggacga
     3901 gaaagatgtg ttttttttgt gatttctccc actcgtatac cattaaaatc actctctaag
     3961 agagcaatta aaatcaattg tctagtctca tcacccatag cagagatagc tttgcgacat
     4021 tctttaaatt tagacgttat ttcttgcatt ctttgttgac attctttttc cataaaatcc
     4081 accctctctt ataagtatct aacagttgct acttctttct gtgcagtacg tctatattta
     4141 acatctgggt atccaattac taatgttgta agaacatgat tactgcgttt tagacctaaa
     4201 agctttttta attttggcga attatttgct acatctgaaa aatatccact aaataaaaca
     4261 cctaggccat aagactctgc cattaatgcc atatttgatg ctgcaagtga accactaatc
     4321 ttatcttttg taattatcat tattgcaata ggagcatgct taaagaaaaa gttatcgtca
     4381 atctcaactt cttttgaata tttaatagct atatttgcaa taggttttat ttttctaaaa
     4441 aatttcactg cttcgttttc ataaattgac tttttattgt ctaaaacaat atatgataca
     4501 tcttgtgaat ttttagcact aggggtatac ctacctgcct caataatttg ctttataatt
     4561 tctgaagaaa cttctttgtc tttaaattta cgtatacttc ttctagattt aattgccatt
     4621 agtaattcat ctgaatctag ctttggctta tttgtaagtt ctataggagg ttcatcaaat
     4681 cctgtcaagg taatagcttt tgtgggacat attgctgcac aatgtccaca cattagacaa
     4741 tcttgttttt taattactga ctttttattt tctataatta tattgtttac tggacaatca
     4801 tttttacaaa gcccacatcc aatgcaaagt tctttgtcaa cttctattat atgttggtat
     4861 ttcatattca ttcatctacc tttcgtttat tagtttaaac tattataaca cgtagacatt
     4921 ttttatattc attggtaaag aatttgatta ccattaaatt tttaatttct ctattaaata
     4981 aatttttcat agaattttaa agtatcatag tttatacata ataaaaaaga caagcttaaa
     5041 acctaagctt gcctttttca tcttttatta caaagtaaat tgcacttact tcccatactt
     5101 cttaacaatt ttattttcta aaattttatt tgtgaatcat actattgcat aaatacaatg
     5161 taaaataatt ctgtattgat tttctatagt taaaaaagtt aaaaattata cttattatta
     5221 atttttatac tcttcttatt taatacaaat ttcttattta acatagattt cttgtctaat
     5281 ataaatcttc accatttgaa gcaattactt tcttatacca ttcaaaactt ttctttttca
     5341 ttcttcttag acttccatta ccactattgt ctctatctac atatataaat ccataacgct
     5401 tttccatttc acctgtacca gcacttacta aatcaatagg tgcccatgta gtataaccta
     5461 ataaatcgac cccatctata gaaactgcat catgcatagc ttttatatgt tctcttatat
     5521 aatcaattct gtaatcatct tctacataac cattttcatc agctatatct ttagcaccta
     5581 atccattttc tacaacaaat agtggctttt catatctatc atatacatga tttagtgtaa
     5641 ttctcaaacc taatgggtca attggccatc cccattgact gtatgaaaga tatggatttt
     5701 tagcagatgt aaatatgttt ccttcagcca tatcatctgc attttcatcg gttctaacac
     5761 aacggctatt gtaatatgaa aatgaaataa aatctactgt atatttattc aataattcaa
     5821 tatcaccagg ttccatttct ggtgtaatac ctttttgctc catatacttt aacgcatagt
     5881 taggatattt acctttagat tgtacatcca caaagaagta attttctcta tctaactttg
     5941 tagcttccca tacatcatta ggattacaac tataaggata tacacttcca gctgcaaaca
     6001 tacatccaat taagttattt gaatcaactt catgtgctat tttagttgca attgcactag
     6061 ctacaagctc atgatgggca gcttgatatt ttatcttttc aacatcttca ccttcttcaa
     6121 agcaaatacc agcacccata aatggagcat gtaaaatcat atttatttca ttgaaagtta
     6181 gccagtactt cactaatcct ttatatcttc taaagataac attgcataat ttctcataga
     6241 aacctatcat ttttcgatta cgccatgcac catacttttt aactaaatgc attggacaat
     6301 caaagtgtgt aatagtgact aaaggctcta ttttatattt tttacactcc ttaaatatat
     6361 tttcataaaa ttgaagtccc ttttcatttg gtgtttcttc atcacctttt ggaaatattc
     6421 gactccatgc aatgctcatt ctatatactt taaatcccat ttcagcaaat aactttatat
     6481 cttctttata attatgatac atatcaatac cagttttagc tggataataa tgctcatcat
     6541 caaaatcaaa catttttagt ttccctgtaa taactgctgt tctatctttt cctgttggac
     6601 atacatctac atttgccaat cctctttcgt cttcattgta tccaccttca cattgattgg
     6661 ccgcagtagc tcctccccat aaaaaatcat tcttaaaact catagtcaaa gcctcctaaa
     6721 attataacca aagcactaga ttatgctaat acctcaatct ttactaaaat aagactgtaa
     6781 ttagattgtc ttctaattca atatttttac tttctgtttc tactacatct aaaaattgtg
     6841 atgaatttgt aataacaatt ggagttacag tactataccc caactctttt attgcatcaa
     6901 catcaaagtt taatatagtt tgaccttttg taattctatc accttgtttt atacatgcct
     6961 caaaacctct tccctctaat tgaatagtat ttaatccaat atgaataagc acttcaacac
     7021 ctgtatcaga aagaatccct atagcatgta gactaggaaa taaggttgta actaccccat
     7081 ctactggagc aactactttt ccatcactag gtattattgc caccccttga cctagtacac
     7141 cagatgcaaa tgctgcatcc tctatatcac ttaattttaa tacttcacct tttataggac
     7201 ttgttactat ttctctttct aatttagtag acttgacttc ttttatttct tctttaccct
     7261 tatttcttac ttttttagac tcttctactt tctcatcttt atataaaatc atagttaata
     7321 caaaagctac gaccattgat atagctatac cagaaagagc tactattaag ttacccattc
     7381 ccccatctgg ttcaatcatt gctggaagtt caaatattcc cattcctcca gttataaatt
     7441 ttctaagatt aaagaatcca tagaaagcgc ctccaatacc actagcaata caacttatta
     7501 taaatggttt ctttaaaggc aataatattc cataaattgc tggctctgta actccaaata
     7561 taccagatat aaagtttggt attgccatct cttttagttt tttatcttta gtcttgaaaa
     7621 atattgccaa cacaactgcc gaacttgcaa atgtacaggc aaagaatggc atcataacat
     7681 tatcatatcc taaagtcata acattgttta tatatacagg aataaatccc cagtgcatac
     7741 caaaaataac aagaatttgc caagtaaatc ctactatagc acctgccaat agtggactaa
     7801 aatctcttat tgaaattaca atttgtgaaa taagtgtaga accaaatgtt gctatagggc
     7861 ctataactat aagtgcaaca ggcactgtta ttaataatgt aagcattggc acaaagaaaa
     7921 acttaactaa atttggaaca cacttattaa ataatttttc acacctagaa gcaaaataca
     7981 ctataaatat aattggtacg actgttccag tataatcaat tgatacaatt ggtagtccaa
     8041 agaaatcaat atatactggt gatgcaaaca ttgttccttt aaataaagtg tacatcacat
     8101 ctgctcctgc tgatatactg ctaccttgta tagcaggata acatactgca gctcctagtg
     8161 ctaatcccaa cattggtttt aatccaaact tcttagctga agtatatcct aagaacaaag
     8221 gaaggaatgt aaataatgca tctcccgctg catttattac catataacca ccagatacat
     8281 cactatataa tcccattgct acaaataatg cattaaatcc tttcaacata ccacaagctg
     8341 ccattattcc taacactggc tgaaaaattc ctgatattat atctatacct ttatctagta
     8401 tattacctga ttttttagtt tctgaacttg tacttgaatc atctaaacca attatttcaa
     8461 ctacatcttt atagacagct tcaacatgat ttcctataac tacttgatat tgtcctccac
     8521 ttttcattac agtaacaata ccttccatgt tttttaatac attgtcattt gctatacttt
     8581 catcttttaa agtaaaacgt aatcttgtaa tacagtgtac taatccacta atattttctt
     8641 ttccaccaac attgtttact atctcttgtg ctaattgttt gtattttccc atttttctcc
     8701 tccatatttc gtttaaatta attttttgaa atttgaaggt ttggccaact caatgttacc
     8761 atccaaccat aagtataatt ttgttagtat cactcctttc aatcattctt aatatactgc
     8821 tgaaaaatta tttcacttac atatttgagt ctttaactac tttagctaaa tgtattgtta
     8881 aatatataag ctcatcatct gttaatatgt agttatattg ttttttaatg aaatttttaa
     8941 ttttaactac acattcaaac tctttattat atttagattt aataatgctt agtaattctt
     9001 tgtctgtctc accttcatgt gcactatcta aaagcaatct ttgcgcaaaa aactttaaat
     9061 gcattataaa tctataataa aacactgatt cttcatgaaa ttctatccta aaatgatacc
     9121 taactatgct aagtacttct tgtattaact tcgtaatatc agatgccaaa gtatgacctt
     9181 cacttaactg agcattcact atatgaaagg ctataaatcc agcctcatct tctggtaatt
     9241 ttatacctgt tttgttttca ataatatcta gtgctttcat tccaatttca aactcttctt
     9301 tataaaatct tttaatttcc caaaggattg cattttttac atttattcct tctttcattc
     9361 tttgaattgc agaatatgta tggtcactta aggatatgta aatactttca tttagcttct
     9421 tgtttaactt tatttgtgcg tattctataa tttcacttga taatttcatg tgttctatag
     9481 gaatattatt gagtaattct tgtagtttgt ttgatatttc tttatttgat attctaaata
     9541 ctttatttac tttagtttta tctattagat tgccttttga tttttgataa ccaattcctt
     9601 tacccataac gataacttct tcatcattat catctaatgt gattacaaca ttattgttta
     9661 atatcttatt aattatcatg attatcctcc ttttaagcat aaaaaaagct tatccataat
     9721 aatgggcata ctccttccta ggatactgct attattaatg aataagctta gcttgtactt
     9781 aaacaattac tacctaattc caattaatat gataaaacat cagacatatt ttgtcaactt
     9841 tttatttcca tatacttcat caatctttta tgttgctttt tgtcagttat aataattatt
     9901 cttattaata ttaacttatt tctttgcatc aatataaata caaaacaagt tatagtcaat
     9961 aataataaaa attctattaa tgtaaatagt taatattata cttcctctac tacattatct
    10021 gtactttatt taacattttt ttcaactcca aaaacatatg tcataataaa tggagcaacc
    10081 aatgctataa atataactat aagtccattt actatatttg aaatcccctt ttcccctgat
    10141 aatccaagta ctgccattat actattttgt ggaacatata aagtcacatg agtaattcct
    10201 gcaaataacc ctgcgattcc tgctcctata gatgctaaca tagcaggttt tttaagtttc
    10261 aatgtaactc cataaagagc tggttcagtt atacccataa tagctgatat ccatgcagct
    10321 gatgctaact gtttcatctt actatctttg cttcttaatg ctacagctaa tgttgcgcca
    10381 ccttgcgcta aattagcaca aacttgagat attaatatta gcgattcttg tcctgtagtt
    10441 gcaaatgctg atatgaatat aggagtcaat gcatgatgca tccctgtcat aacgataaat
    10501 ggcattgcag ctgctaataa acaaaccatt ataaatccta accttccttg tagtaaattt
    10561 attatactag ctaatccctc tcctaagaaa tttcctattg gtccaattac tattaatgct
    10621 attggcgcac ttattaataa tactaaagtt ggatttaaaa ttgtttttaa catgctaggt
    10681 gttaatttat caatgaaatt ttctatatat gacatcatcc atactgttaa aagtgcaggg
    10741 ataacagatg ctgcatatat aacaccttga attggtactc ctataaatga tatagggtcc
    10801 ccacttgata cccatgcaga gaaatttgga tgtaaaaaca cacctactac tataactgct
    10861 attgatgtat taacattaaa ttttttagct gcatttattg caagtattat aggcataaag
    10921 taaaatgcta catctcctat tatatctaat actctatatg tacttgaatt tgatgatagc
    10981 caattaaaag tggtgcaaag agataatata acttttatca tcccagatgc tgtaagggct
    11041 ggtatcatag gtgtcataca accagttatt gtatctatta tattatttaa aatactattt
    11101 tttttatttt tattttttat atcgctttta atatctcctg tggtatttat ccccttattt
    11161 attattgcat taaatacaac acctacctca ttacctatta tgacctgata ttgagttgaa
    11221 gttgagttta ctccaactac cttatctata gattttaatt tatctgcatt gactttcttt
    11281 tcatctttta agatgaacct taatcgtgtc atacaatgag ttaagtcaat tatattatct
    11341 tttcctccaa gtccatcaat tatcaattga gctacatctt catatttatt cttcatacct
    11401 tatcctctct tttaaaataa tttttaatat aattttaatc caaattaatc tttttactcc
    11461 aagcttgtaa tagtgtattg taatttaata agctagtatc ttctacaata tggtcacatt
    11521 ttcctagtac ttcttttttc cccacaccaa ttgatgtcat attggcagca tttatagctt
    11581 taatacccga ataagaatct tctattccta cacaatcata ttgttttaaa tttagcatct
    11641 tgctcccttc aataaaaata tcaggatatg gttttcccct ttttaataaa gatggattta
    11701 ctatacaatc aaattcatct tttactccca aagattctaa tatcctaggt gcattcttac
    11761 tagcagatgc tattcccaat ttcacattat tttttttaag ttcttttata agctcattta
    11821 tccctggtaa tatatcttta tatgttaatg agtttattaa ctttatataa atgttatttt
    11881 tttcttcaca cacctttaac ttttcctctt tagtataact atctacttta ttagcagata
    11941 acaatatttt atctaatgat tcttccctgt ttatgccttt taatttttca ttaaaagttt
    12001 catctatttc tatatctagc gattttgcta tctcatgcca agcttcaaaa tgatacttag
    12061 cagtatctgt tataactcca tcaagatcaa ataagactgc tttcatatta attactccct
    12121 ttaaaacaat tattaacttc tattatgttc tttgataatt ttatttcttt attatcatgt
    12181 aatatggtta tatttctacc tttgattaac ttataataag atttatattc ttctatattt
    12241 acaaaaacta aattatctct aaataatata ttaaatttaa tatttttcca gtgtttaggt
    12301 atccttggtt caaaacttaa tttatcattt tttattttca ttcctgcaaa tccatatact
    12361 aaactcatcc atgttccacc catattagca gcatgtattc catcacttgt atttttttgt
    12421 aggttattaa tatccattaa tgctgtgtcc ataaaatagt tataagcttt ttcatgattt
    12481 ccaatttcac ttgccatcat tccaaatatt gaccttgaca aagatgaatc atgagtagtt
    12541 attttttcat agtattcaaa atctctcttc ttttgttcta agctaaactc atcagggaaa
    12601 agcaacgctg aaagtacagt atctgcttgt ttatttactt gatatctata tattgttaat
    12661 ggatgataat ggagaagtaa tggatatttt tcttttggtg tatttttaaa atcccatact
    12721 gatttttcta aaaatgaatc gtcttgtttg cttattttct tctcttcatc atatggtaaa
    12781 tacatatttt gagcggcatt tatccagttt ttcacttcat attcttgtaa tttaactttt
    12841 ctaaatactt catttgaaaa taaattatgc ttaaatttat ctaccatctg tactgcatat
    12901 attaaattat acttagccat taaattagtg tagtaattat tgtttactat tgctgtatat
    12961 tcatctggtc ctgttactcc atttatacag aatttattat tttttgattc tatataatct
    13021 ccaaattcaa cccaaaatct tgatgtttct ataagaattt ctaagccatt ttgcatcata
    13081 aattcttcat cattagttgc ttcaaaatac gttctaacac cataagctat atctgcattt
    13141 atatgaaact gtgctgttcc tgctggataa tatgcactgc attcattacc atttatagtt
    13201 ctccatgaat ataagcaacc tttatttatt ccaagttctc tagctctttc tcttgatgca
    13261 tctaagattg agtatctata atctaataaa gctctagcaa tggatggttg agtatatata
    13321 aaaaatggta atatatacat ttctgtatcc cagaaataat gcccctcata gccatcacct
    13381 gtaagacctt ttgctgatat attagtcttt ccatctcttc ctgctgattg ataaatatga
    13441 aataaattgg tttttatccc cagttgaaga gttttatcgc cttcaatctc tacatcagag
    13501 gttgtccaaa actcattcat tttctttctc tgaatatttt tgactttatc aaatccaata
    13561 ttacatgctt ctcttaaaac caattctaat gattttaaat gtgcttctga ttctaaacat
    13621 tttaacgact ccagacattc taatgatttt aaacgttctt catttagatt taaatcagaa
    13681 tatactctac tatagcctac aacaatttct aaatttaacc tttcatcttt tttggcatag
    13741 acttctattt ctcgctcaat acattcatct gaaacattat aggtctcatt tgtaatattt
    13801 ccacaagtaa tatatgaatc aaacccacac cataacccta atctacttct ttctgtaact
    13861 aaattcataa aatacttatt gttatatttt tttacattaa ttttaaattg cttcttattt
    13921 atagatgcca ctcttgggtc atctactttt tcacaattaa acttctccat actattttcc
    13981 attttatttt taaattttat ttttccatta aaattcaatg gtgttattgt atatgaaatc
    14041 atcattaatt cttctatatc ttgtgatact aatctttcta tagatacttt aacttttcta
    14101 ccacgagagt tttcccatat aaatgaacgt ttaagaatcc cttcatttaa atctagtatc
    14161 ctagtatgtt cacttgtaat accttttgat aaatcaaagc aatctccttc aatagagaaa
    14221 tttactatat gagcattagg taacttacag atagtctgat tttgttttgc atagccataa
    14281 gcgctttctc catatgtaat tggagattct tcataaaatc catttacata tgtacccata
    14341 ttatctacat actcattatt aaaatcagac tcttcaatat tccctctaac tcctaaatgt
    14401 ccattagcta gtgtaaacaa cgtttcattg gattttattg tatccttact aaaccctagc
    14461 tctacaagtt ggtccttagt agtaaatatt aaactcataa taacactcct ttcttaaaat
    14521 gaattatgca tgagtttcca tatcattaaa taaaatttct ccatctgttt ctattacttt
    14581 tttataccaa aaagcacttt gttttttagt tcttttaaat gagcctcttc catagtcatc
    14641 agaatcaaca tgaattatgc catatcgttt tgtcatcttt ccttcactta cactggttac
    14701 atctatacat ccccacataa gatatcctat aagctctatt ccatcttcat ttactccaag
    14761 aatcatattt ttaatatgtt ctttcatgta atctatacga taatcatcaa ttatttttcc
    14821 atcttcattt acaatatctt gagtacccag tccattttct actataaata aaggtaactg
    14881 atacctttca tataactgat tcatagttat tcttaaccct acagggtcgt tttgccatac
    14941 actatttgat tttggaagat atggattttt tatggtttct ggtccgtttg cctttgattt
    15001 ttctaaacct tcagctctag ctgaactaca agcactagaa taatagctaa aagatacaaa
    15061 atctacagta ttatccttaa gtgttgataa atcttcctct tttattatta attttatttg
    15121 atttgatttt aaataataac tcataaagct tggatacaca cccctaactt gaacatcaga
    15181 aaaaaacaaa ttatgcctct catgctctaa agttgcaaat acatcttctg gtttacatgt
    15241 gtatggatat gtttttccag cagctaacat acacccaaac ttaaattctt tatttatata
    15301 ccttcctatt tctatagttt ttgcattagc taataattga tggtgtgctg cttgatattt
    15361 tttctgaagt tgattttcat cagctataaa agttaaccca gcacctatat atggaatatg
    15421 cattatcata ttcatttcgt taaaaggaat ccagtatttg acatcatctt tatatctttt
    15481 catcaaaatt tcagcatatt ttacatataa attaaccact cttctatcag cccacccaga
    15541 atatttttca actagagaat aaggtatatc aaagtggctt atcgttatta atggctctat
    15601 attatatttt tttaattctt ttattatatt atcataaagt tgtaatccct tttcatttgg
    15661 ttcactttct tctcctgttg ggaatattct tgaccaagat atagaaaatc taaaacattt
    15721 aaaacctatt tctgctaaca ttgctatatc ttctttgtaa ttttcacaaa atttaatccc
    15781 tatatgactt ggatagtatt gattattttc atttaaaata ttatcctcat ctaaacatac
    15841 attttttaat ctcttatcat ttaatgggag tttatcaaac tgagataaac cttttcctcc
    15901 atctaaataa aatccttcac tttgattggc tgaaattgcc cctccccata aaaaatcttt
    15961 ccctaatttc atgcatctac ctctttcaca gtataaaatt ttataatttc tatctcatat
    16021 ttagttataa gatttttttc atactatacc ttttaaataa ttcaatttaa aaatccaatt
    16081 atatttttta ctcactataa ttaatattgt ctattttcaa tactttcata ttaaatatca
    16141 atattagata tctatgtata taattatata tatagcaaat acatttttat atcctcatta
    16201 ttgttatctt attctcatat attgctgtat atttatatat ataaaaggat ttatttcgaa
    16261 atagaggttg tattgagaac taaaatttag actttataaa tgaatggaat tttcattgtt
    16321 gaaatactga aaatatattt gatttcatat aaaagaaagt gcctcatgaa ctaagttcat
    16381 tttgagacac tccctttttt ctccaagcta ttatatcttt ttttaaattc taatggagag
    16441 actccaattt tttctttaaa tactctgtaa aaagtttttg tacttccaaa accaacttct
    16501 tcaaccaaat ctacaatgga tatattgtta ttaagtaata tccactttgc tttttctaat
    16561 ctatattcat ttaaaaaagt tataaatgtt tttcctgtat tttttttgaa aaatttagta
    16621 aaataatata cactaaatcc tacttcataa gacacatctt ctaattttat aggttgttta
    16681 taattttttt ctacatattt gaatatattg ttcaatctct ctaatatctc tttagagttt
    16741 atttcatatt ctactgtatt ttcttcaatt tctctaggaa tctgtctata taatatagga
    16801 attaaattat acattttacc ttttattgca taactatatc cttctatttt gtataggtct
    16861 tcattgtaga tatctatcaa tatatcgaaa actgactttc ttatttttgc tgaccaatct
    16921 ctactacatt tttttatact actgaataaa ttaattaagc tttctttctc ctcatttaat
    16981 aaaattaaat cattaaaaaa agatatatca aattgaaata ctaatctttc acttcccggt
    17041 gatggcagta tataatgaat atctcctcct tttattatca ctatctcgcc tttttttaat
    17101 tgcataggct tgtcatttat aaatagattt actacacctt ctgttataag taatatttct
    17161 atttccttat gccagtgtgg tgttgttaat acttctcctt catttgatag agtacgaaaa
    17221 ggaaattcat gtattaattt aggcatttct aaatatattg ccatatatat cctctcctct
    17281 ctagtgtcta aaaattaatc tatactattt aaaagaatac acattttatt ttaaaaacct
    17341 caaatttata atttatacaa tacctacact tcataaaata tatctaatat ttcttttttt
    17401 gtatgtgcat ttaaaagtct ttcacctata tttttaccac ctaaaatgta agctatttta
    17461 gatattaata tcatatcttc attacctcca gattgtggca tagcaaacat aattattacc
    17521 tttacaggta agccatctat acttggccaa tctacacctt ttttagattt acctattact
    17581 atggatgcct tctttacata ttttgttttt ccatgtggca tggccatttg ataacctata
    17641 ctagtagagc ctattttttc tctatgtttt aatgccttta taaacttact ttttaaagtt
    17701 atacttcctg tatcgtataa tttatctact aattcctgta ttatgccttc ttttgtagtt
    17761 gatttcaaat ctaaaataat gctttcttct gttaatattt ctctaatttc catttgtttt
    17821 ctccaataga ttattcttaa ataatatttt aatatcctct ttgctcttgc aatctattat
    17881 atagtttata tagttctttt gcctatataa atttgatatt tccattaaaa tattctttaa
    17941 aaaactttga ttactaattt ctaaataaat atcaatcgtt ctagtaacat tattgatatt
    18001 cattatccct ttatttaatt tactttgctt atgtatatat atatttaaat cttttcctaa
    18061 tgaaatagat tcatatttac tccctaaatt cacacctatt aaactttcca tctgagctac
    18121 atcaaaatta aaatatatat tatcttctaa atacattcct aataagtttg tatctaagtt
    18181 catacttttt ttaggtttag aaagtaaagc attttttata ttattaatat cactttccat
    18241 taatagtact gatacaacta tatgtaattt atctttcaaa tctaagttta cagtagatat
    18301 tacaaagtct acatcatcta aatttcgctt actcaactga tgcataggaa ctatatcaac
    18361 tatagtccat tcaggaaatt ctctttttaa tctggctgca aggagctgag atgttccata
    18421 tcctgtatga caaactacta ttactctttt actactcata tttctttcta ttgccgcttg
    18481 aaaatatgtg gcaagatacg aaacttcatc tatactaata ttcttcagat tatcatactc
    18541 tgtcataata tttatagtca tcatacataa tcccagcaca tctgaaaatc gctcttgtat
    18601 ctctcctaac aacgggtttt ttatttggat atcatatctt aatctgttta acataggcct
    18661 tacatgagat gctagacttt tctgtagtaa gtcatcattt ttgagattta tatttaaaaa
    18721 tcgtgacata ttctctatca ttatagatga aactttttca ctttcactta atctatctga
    18781 ttcatcattg taactactat tattttcgct actaaatcca gatgatacca aaaaaatata
    18841 tatgtacata atttcatctt tcgttatttt tactctgtat ctattttcta tcttatctat
    18901 aagtgtagtg acatttttat atactaactc gtccaaatta tctacagaaa tttctctttc
    18961 ttcctgagat tctatttgat taccttcttc gattctcttt aaacatataa gtatatgggt
    19021 aattaaattt atatagtagg gctgatttat agtatatcct aaattgtatt ctaattctgt
    19081 aattatagtt tctacaaata taatagaatc aatatcaaat aaatttatca atgcactaaa
    19141 tgtagcagaa tctaatcttg ttaactcaga tatatcatgt tgttcataat tttcatctaa
    19201 taaatcatcc atcattttgg caatcgattt ccttatatcc acttctttac ctataatctt
    19261 agttccttct aaagttttat taagttttaa attgtattct tttatccatg cctctatata
    19321 tttaaaatca tttactatag aagttttact tacataatat ttatctgcta actgatttat
    19381 tgaagttata ttatttgaat ttagcaataa atactttaaa atctccattc ttctctgctc
    19441 tactgataaa gatttatttt ccttcgattg tatatttaaa ctattaatta agtctatgtt
    19501 cttctttgct aaatcttcta ttaatattcc atagcctctt tttatatcaa tttttatatt
    19561 aaaagtttct aaatatttct caatcatctt caaatctttt tgtaaagttt tatcagatac
    19621 atttaattta tctttaaagt attttatagg tctatattta ttttcgttta gtatcaattt
    19681 aagaaattca atttgcctcg acacaagcat acttagccct ccctacctat gtttatatat
    19741 ttctatgttt atattaagta ctattttaac atatttacta actatgtaaa attactaaga
    19801 tacttctgta tcataaaaga atttatgata caccttacta aattgatata atagataata
    19861 taatttcaaa ataaaaatta aggatattta gaaatagtta actgattcta aatatcctta
    19921 ttattattct atatacttgt tgttattcca ttaattattt ttactattat ttataattta
    19981 agcaccaagt aattcaactt cactattttc actccttata gtaggctttg ttacccctat
    20041 aatcaatgct gttattactg taccaatcaa tatacaagct atatatgcaa ctggtgcact
    20101 acatgcaaat ggtattacaa atattccccc atgtggtgcc attaaagtta tatctaaact
    20161 catacatatt gccccaccta tacaagaacc aattatattt gctggaatca ttcttaatgg
    20221 gtctgcagct gcaaacggta ttgcgccttc tgttatgaaa gatgccccca ttatagcagt
    20281 tggtagagat gactttcttt cttctttagt aaacttattt ttgaatatta acatagctaa
    20341 tgatattgct aatggaggta ccattcctcc taccattaat gctgctgatg gttcaaatat
    20401 attacttgaa aacatagcca atccaaaagc tgaagctgtt ttattaatag gtcctcccat
    20461 atctgatgcc atcatccctg ctaatattgc acctaataat actttattag ttccagacat
    20521 actttgtaac caagattgta aagcttcatt taaccatgat gctggcgtat taactacaaa
    20581 gaacattata gctccactcg taaatgcaat caaaagtgga catatcaata cagcatttac
    20641 tccttttaat acatctggta aattttctgt tatcttcatt actcctaaag ctatatatcc
    20701 tgttgcaaaa ccagctacca taccacctat aaaacctgaa cctccaataa ctgccataaa
    20761 accagctatc atagcaggag caaatccttg tcttcctgct attgatttag ctataaaacc
    20821 agcaagtatc ggtataaata acttaaatgc tgaatcgcct ccaagttgtc caaagaatcc
    20881 agctataggg ttgtatgttt catgagttgg gtctgatgca aatataccaa acataaaagc
    20941 tatggctata ccaattccac ctatcactac aaatggaatc atttcagata caccactcat
    21001 taagtgctta taaacaccct ttttctctga cccttgaagc atttcttttg aatcttctaa
    21061 agtctttcca cctggtttaa tttctttagc cattccattt tcagcgttta taattaaatt
    21121 tttagctaat gaaacattct tagcatctac tactttcttt tgtagcactt tctttcctat
    21181 aaatctactc agttgaactt ctttatcaca agctattatt acgtattcag ctctttttat
    21241 atcttcttta gtcaacttat tttctacacc tatagctcca tgagtttcta ttttaacttc
    21301 atatccaagt tcttgccctg cttcctctaa tgcttttttt gccataaaag tatgagctat
    21361 acctgttgga catcctgtta tcccaactat aagaccttta ttttgattat tactaaaatc
    21421 tcctgattct gcagctttat tattaaatat acttaatatt tcgtatggag tttctgcact
    21481 tagtagatgc ttaagaaaat tttcttccat tagatatgta gctagtttag atataatctt
    21541 aagatgttca tctgaacctg attctggaac tgctatcata aaaaatgacc taagtttttg
    21601 accatcatta tctgtaatct ctctatctgt tcttaaatac atcattacag gttgatttac
    21661 tacatttgac ttagcatgag gtatagctat taaattaccc atattagttg atgattcttt
    21721 ttcacgttta ttaatatcag ctataaactt ttctttatta tttatataat ttccatggta
    21781 caaatgattt gccatataat taatcacatc tttttttgtt tgtaattgtt tatctagtac
    21841 aatacaatcg cttcgtagta ttttacctat cataaattct cccctccttt taatttgtta
    21901 cctcataatt aatttttatt tttataaaag cactttaact tatctatagc attgaataga
    21961 ttcattttaa actctataac ttctcttgca gcttttatac atggtggata tatagtatct
    22021 ggctcatata agcttgggtt ttgttctaat agttctctgc acttcttata atatgccgac
    22081 ttaacatcac tcgaaatatt tattttacaa actcctagtt taactgcttg tgctatttct
    22141 tcatctggat ttgatgaacc accatgaaga actaaaggta tatctactac ttctcttatt
    22201 tcttttaata aatctagttt aagctctggt ttaaaacctt ttggatatat accatgtgct
    22261 gtaccaattg caatagctag tgtgtctact cctgtttttt caacaaaatc cttagctaat
    22321 tttgaatctg tatatattat ttcatcagta ccaccttcac ttgatgttcc tgttgttcct
    22381 attgttccaa gttctccttc tacggacaca tttaatcctt ttgctatttc tactatttcc
    22441 ctagatatag ctacattctc ttcatatggt aaatgtgagc catcaatcat tactgatgta
    22501 aatccacatc ttattgccct taatatttgt tctttatttt ccccatgatc taagtgtatt
    22561 accataggta ctttactctt atttgcttct tctatgcaac tagctacaaa gctatctcct
    22621 agaaaactta gctcatttgg gtgtattgca agtattactg gtgcattttt ttcgttagca
    22681 ctctgtacta ctgctttaag tatttgccca cttcctatat taaatgctgg tacagcaaat
    22741 tgattttctt gtgccacttt tagcatttcc ttcatgttta ttaacatatt gtacctcccg
    22801 atattttaaa ttttaggttg aatttgcttc ttgttaattt tgttgttgtt tatatttaaa
    22861 taatatcagg gtaatgaatg tcagaaaata acaatcgttt tccttagtga aaaggaactt
    22921 ttattataca ctctaagttc cttttcacta aataattttt agaagtctgc atcatagtta
    22981 attatatttc tcatgtacat cttctctttt taagtgtttt atgctttagc cttcctagat
    23041 tttataataa acaattaaga tacattaact ataaatttaa agatactcat gcaatagtta
    23101 atgctatatt agagtcaaaa aaattaaaaa gatattagct atttggccaa taccttttct
    23161 tggattccaa tagtatatac gatttataga aatcttactc acgattatct aatgttttac
    23221 ttccataaac tttacataaa acaccaaagt gacaccctcc aaattcatct ctagctaata
    23281 aagtgatttg gttttctaag caccaattta taaattagcc tttgttatct tatgtaaatc
    23341 tttttctatc taatttaaaa attattccta atgctatata gcatatacca attactaata
    23401 caccataagc catagatact cctatcttaa attcttgcat attaattaca atagaaactg
    23461 aaatagattt attacaaaca ccataaagca aggctgacat tgtatattat ccaattgtat
    23521 gaatgaatac taatatagct ccttttaatt aaatgatgct atataaatca tatttatccc
    23581 aatttttaat ctaacctatt tatatgtata ttccttttta ataaaaaaag atattgacta
    23641 aatagtcaat atcttttagt tgatttaaat acccacaatt ttaatctaat ttttaagtgt
    23701 ttccttaaca taatcttata aatattaaaa tttatctacc tataaaattt ctccattaaa
    23761 ttttattaca ttttatctta aaacaattat aatctgacct taatcatata ttatattata
    23821 taaatatttt taacaaactt aataattaaa taactatatt ttattatcca tcttataaat
    23881 gtttataaac tttccactat tcttcttcaa taaattcaaa caaattttct actgtagtat
    23941 cgaatacttt agcgatatcc atagctaact tcaaagaagg attatatttc ccattttcta
    24001 agtgtacaat agtctcacgt cttaccccaa ccaatttagc aagttcattt tgcgtcataa
    24061 ggagtttttc tctgtattct ttaatttttg ttttcatcaa tattgccact tagttacata
    24121 tccccctttt atcaaagtat atatacaaca ctaatttaga taaagactgt ataaataaaa
    24181 ctgcaatgag gattatacct gtatctaggt ttgatatatt tatattactt gtataaggtg
    24241 ttgcaaagaa aatagatatt attactatag aatatatcat tatttttatt gcaatcttat
    24301 taacctttga tagtataaat tcagatgatt catcaactaa atcattatat tttttattat
    24361 aaattgaata acatccaaaa actattaacc aactcaaccc tggaagagaa gcagtgcttg
    24421 gacctttaaa aatatactta gtggctaata cagctataaa aaaataagtt attacaagca
    24481 actccaggat aagctttgat cttacaccag tttctgattt agacatataa aatcactcct
    24541 taaaaattat attctctata ctctttaatt ttcgttttta tcaatattat cacttagttg
    24601 catattccct ttctatcaaa atgtatatac aaaattaatt tagataaaga ttgtataaat
    24661 aaaatagcta agagaattac acctatatcc aaatttgata tatccaaacc tcttgtataa
    24721 tttgctgaaa agaaaacagc tattagcaaa atagaatata acattatttt tgatgcaata
    24781 tgatcaacct ttaataacat aagttttgac gcctcgtcaa ctaaatcatt atatttttta
    24841 ttatacatga agtcacatgc ccaaaaagcg aataaaatta taaaagtaat acaaagattt
    24901 ccctctttaa aaataaactt ttttaataat gagtctataa aaaaatagga tatcataagt
    24961 aactctgaaa caagatttgt tttaacacca agctctgatt tagacatata aaatcacccc
    25021 ttaaaagtta tatatttata acaccttatg ttataaatat ataacttttc caaataaatt
    25081 gcaatagaat attgaaaata ttcaataata tcttcataaa tatattttat aaaagatttt
    25141 ataataaaca ttacaataca gtactaaatt agtttatttc atctatcatc tcaatcatat
    25201 catttactaa ctattattct aatgagcata taacattgaa acttataatt atacaaccta
    25261 aatgcctccc aatgtaccct caaaacatca tttcctgtaa ctgaagtata attggtatat
    25321 tttatcactg aaataaaaaa acactagtca ataaagacta gtattttcaa gtattttatc
    25381 attctttttt taattattgg agacgaatca tcagaataat gcccataatt tatctatatg
    25441 caaattctaa atttaaaata aagtttcaga taaatttact attctatgct atgatacaac
    25501 agaaaaaact gaaatctatg agtggtagct tcatataatc ctagttccta cagtaatcaa
    25561 aactgaggtt tattctatat gtaactaatg ataaatttta ttataggagt tattagatct
    25621 atttgtgtta ctataagtag taattatata tatgataatt ttttaacact tttctgttgg
    25681 ctatatagaa agtggtttag aatttaaatt taaataaaat ttaaattcac caaaaagaaa
    25741 tctatattag aaaccactac tctattccac cagattgtaa ttttttgttc tttatatcac
    25801 aatgctatac catattaaat tgaaaaataa gttttaaatt tatttgttac aattcattaa
    25861 ttcaaaaaaa tattttgagt catgagtttt gtaaagattt agccatgaat ttaatgcttc
    25921 tgattcaaaa acatctaaaa gtttcaatac ttgaaacgta aattccaacg gagcaattcc
    25981 tgaagccgta actaaatttt catcactaac tacagattcc gttttataat atttttctcc
    26041 agagtaattt ggtattacca ttttaagaaa ctctaagtca ttacttgtat gatttctaaa
    26101 atctaatagc ccttttttag ctaggcctaa tgtagctcca catatggctg caactataga
    26161 atcttgtctt aaagcttctt taactttttc taatattatc tcatgattca tagataacca
    26221 agtatttccc cctggcaaaa ttaataaatc cttactttcc atattaaact catcaactgt
    26281 aatttcaggt aaaactttta acccacccat tgttataata ggatttttat caattcctac
    26341 agtaattact tttagtggct ttaatccttt tttaaaatat cttcctgtat ttaattcagc
    26401 agttaaatat gccacttccc aatctgacat agtatcaaat acatacatat atacttttct
    26461 atttttcatc ttttttactc cttatgtaat taatttatat atctaattat aaaataactt
    26521 aactgacata ttcagtcagt taagctatta aatttgataa taatcaatta attctagtaa
    26581 atcttcaatt attttcttcc taaggcttag tggttcaatt acttgtattg tctttctata
    26641 aggtaaaagt atatttggta tgtacttgca tattacttcc tcttcaagca taaatattat
    26701 tttattaggt gttctttctt tcaagtagtg ccctaaaaac caatgttggc ttaaactatc
    26761 taaagaatct atactccctt ctataactaa ttgaattata ttttgttcat cttttatttc
    26821 aggtataatt ccttttataa aaaattcact tgctgaaaat tctgtcggtc tgttaaatgt
    26881 atttgatgtt tctatgattt cactaatcct atccactctg aaactacgaa cctcatttct
    26941 catattacaa aatgcaacta cgtaccaatt attattccag tgaacaattc catatggatt
    27001 tataattcta tattttgatt ttactttacg acctgcatga tagttgattt ctacagatag
    27061 ctcctttaat atactattct ccaatttttt aagtactgat tctatagaca ctttcccaat
    27121 tggttttatt acttcaaggg ctcttaagtg gtttgttaaa atatcttctt gtttttgatt
    27181 tgaatacatt tttaacttta atatcgattt atctaatgct tcgtctaaga agtatccttc
    27241 ttttttagca aatagtgctg catgaagtag agatttttgc tcttctatat caaaaaaaag
    27301 aggtgcttta gtaaaattat ttaaaaggct atacccacca ttatgacctg tatctgaaat
    27361 tataggtact ccactcgcag aaagtacatc aatatatcgg tacactgttc ttatatttat
    27421 ttctaatttt tcagctatct gttttgctgt aatttttttg tcagagttta acatccacag
    27481 tatagacatc atattgtcaa ttttagccat gtagtttcac ctctttctat ttgttatata
    27541 aagttattat ataacttttt gattgatttt ttacaaaaaa acattagtaa actgctaata
    27601 atttatacta agatttattt caaatattta tagatagtct ttttctatag ttaagttatc
    27661 cattaaatta catagtagta tatctatttt agttgatata ttttcagcta cctcccttga
    27721 atattattac aataagtcta aatcttcttt cttccataaa tatattatga ggaaagacta
    27781 tcatctttaa tggtttaata gtataaaaga tattaattta aaaaaatcta tttttatatc
    27841 agatgggtat tgttttttat aaaactgaaa aaatcaccta atagaatcta tgatttttta
    27901 acataacctc cataaattag ttccaattat cacttcaaat tcaaattttt atctgaagaa
    27961 tatacaatca tatttccata ctcaacataa tattgagtgt ttggcttgta tttacaaatt
    28021 attattctaa caaaaacaac tatacataga ttaaaatcat cttctaaaca taactactaa
    28081 aattgaatta atgatatcaa ttccattaat ctcttttaat aaaaaattct cttttctata
    28141 tgaaaattat ttcaaaactt ttaagttaaa tacaaaaatg actataaata gatttttatt
    28201 tacacaaatc tatttatagt cactatagtt tatccaataa aataataaaa taaatatgta
    28261 cacaataaat gttatttacg tcttaagtat ttatttgtta gatttttaat taaaaaaaac
    28321 aagctaatga acattaatgc taaatctagc attatattgc tttgatctcc tgtttgtaca
    28381 ttttgaccta cattactatc taaactttca tctgtatcta tatttatatc tggttttcca
    28441 ttcccatctg tatctatatt tatatccggt tttccatctc catctatatc tatatttata
    28501 tctggttttc catctccatc tgtatctata tttatatctg gttttccatc tccatctgtg
    28561 tctatattta tatctggttt tccatctcca tctgtgtcta tatttatatt cggttttcca
    28621 tccccatctg tatctatatc tggtttgcta tttcctccat tatctgggtc tggtttacta
    28681 tttccaccgt tatctggatc cggtttgcta tttcctccat tatctggatc tggtttacca
    28741 ttgccaccgt tatctggatc tggtttgcta tttcctccgt tatctggatc cggtttgcta
    28801 tttcctccat tacctgaatc cggtttgcta tttcctccat tacctgaatc tggtttgcta
    28861 tttcctccat tacctgaatc tggtttgcta tttcctccat tatctggatc tggcttattt
    28921 agatttggat tacctgtatc ataacctcct gagccagtat ctacattttt atcaggcttc
    28981 caataatcat ctactccatc attatctgta tctattgctg gacgattata atctgtatca
    29041 gggtttccat ctccattggt atctatattt ttatcaggtt tccaaatacc atctccattt
    29101 ccaccttctg tactaggctt ccattcacct gtattatcag tatctatgtt aatatctggc
    29161 ttccaatcac cactcgtatc tatattgata tctggccttc catcaccatc agtgtctata
    29221 tttatatccg gtattccatc cccatctaca tctacatttg tcatatctaa ctttaacttc
    29281 ttttcatcct cactaccttc aatgtaattt atatcatctc caatatattt tacagtaata
    29341 gtttgttcag tagtaaaaat atgatgattg ctatctaaag gtctccattc aatagatgca
    29401 gtactataat tatgactctc actaccctta ttatgagttt ttaattctac tggatcttta
    29461 tattcctttc cattaatata gaattgtacg taacctcttg gagaggcaca atctggtcct
    29521 tctttcttat ctggtgaaat agtaacattt aatgtaaacg tatctgttgg tttaaaaaca
    29581 tcagttttag ctttagactc ttctacaact aatgaagttt ctgtatcagc aggaataatt
    29641 tctgccttat aatatgctct atgcccccaa taagcatcct taaaaggata tatactcgaa
    29701 aactgtgttg atgtaatgct taattgatat ttcccagcat caacttgttt tgtaagatca
    29761 tcacttccta aatttatatc tggttccatc gtttcctcat ttaaacgttg agaactaata
    29821 gtcataaatt ttttatctgt gagtttttca cctttaggag taattattgg aataccacca
    29881 tctttaaata tccaatctaa aaatgatttt tctacgtctt cttcaaatgg taatccatca
    29941 tatcttttaa taatcaaata tggtggagta tcatcaatag taaattcttc atattgcttt
    30001 aaaaattgag aacctgaacc tatatcttta atataaaaat catctggttt tagaacttct
    30061 ccagtaattt tatctataac aactaaatta acagatactt cagatccctt aaattgatca
    30121 gagaaccata agtaaagaat cccttgagca tctgtataac taggtgctcc ataaggataa
    30181 atttttccat caattagcat tttaaaatca tcaactagtg tagtactaac tttatcttgc
    30241 cctaaatacg ttagagatat tttattcata aaaacttttg ttttcttttc taaatcaccg
    30301 tatgcaactg ctccacctaa acttttgaat gttgttgctt ttaatgaacc acctgttact
    30361 ataacatctc ccgttgtagc acttaggtca aaaatccaat ctcccactcc tgtcatataa
    30421 ggtaaaatcg ttcctccagt tacaagtata cgatatcctc tatttgttcc tggattaaca
    30481 catccatccc caaatgcact accatgtgca cctccatatg aataggaaag tccaccatta
    30541 attgtaatat tcccactata accagaacct gtgctaggat ctactactga gggacttaat
    30601 gcattctttg ttgttgtata gtatcctcca cctattccag ctccatggta tgcaccttta
    30661 gcagttataa tacctccatt gattgtgata tctccaccac taccattacc tcctccacct
    30721 attccagctc catatcctgt attacgactc gattcttgac ctatagcagt tatagcacca
    30781 ccattaataa taatatttcc tccactttca gtatttccac caccaatacc tgcagaataa
    30841 taatttccaa caacttttaa acttcctcta ttattactat ctagtagtgt aaggcgatct
    30901 ccttttttta acttgtctcc attttctaga gttacatctc taggaatttt tccaccctca
    30961 ggaactataa actctccttc aatatctcta tttacaacag aatcatcaat aattagagta
    31021 gtaccttttc ctgctctcat acctggataa tatacatcac ctgactctag cttgttttca
    31081 ctaccatctt gtaatataac atgtgcatat gcaccaccat ctttatctgg tgttaaagta
    31141 aatgggctat tagatgcagt tttaatattt actccatcaa atattaattc agcttttaca
    31201 tctttaggta taacaatcct atgtgttgtt ggagtatttg gattgttatt ttgaattgtc
    31261 atttgttttc cactaagaat agttaaaacg ccacttgcaa atttaaaatc gacatttatt
    31321 tctccaccac taattttaaa gtctcctaca gacgtaggct cttctgcagt ggcttcttct
    31381 tctacaacta ctgcattagc atctccttct gcatctcctg cattagtatc tccttctgca
    31441 tctcctgcat tagtatctcc ttctgcattt cctgcattag tatctccttc tgcatctcct
    31501 gcattagtat ctccttctgc atttcctgca ttagtatctc cttctgcatt tcctgcatta
    31561 gtatctcctt ctgcatctcc tgcattagta tctccttctg catctcctgc attagtatct
    31621 ccttctgcat ctcctgcatt agtatctcct tctgcatttc ctgcattagt acctccttct
    31681 gcatttcctg cattagtact ttcttctata gtatctgcga aagtatttga cgcattaaat
    31741 gatgctactg gtccaagtcc cattgagata cttaaaatca ttgatagtgc tttcttttta
    31801 catttttgtt gcataaactc cccctcccct taataatttt taatatacac tgtatacatc
    31861 cttatataca ctctaataat tcttaatata cgctgtatac attctaatgc acactctaat
    31921 aatttttaat atatacttaa aacttatatt tgtcaatgaa tatactgttt tttca
//
LOCUS       DAMJWC010000046        31114 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMJWC010000046 DAMJWC010000000
VERSION     DAMJWC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31114
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.046"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(222..605)
                     /locus_tag="PC503_002440"
                     /pseudo
     CDS             complement(222..605)
                     /locus_tag="PC503_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      831..928
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            983..1159
                     /locus_tag="PC503_002441"
     CDS             983..1159
                     /locus_tag="PC503_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528407.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            1385..1585
                     /locus_tag="PC503_002442"
     CDS             1385..1585
                     /locus_tag="PC503_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2528408.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            2590..3435
                     /locus_tag="PC503_002443"
     CDS             2590..3435
                     /locus_tag="PC503_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2528409.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(3659..3823)
                     /locus_tag="PC503_002444"
     CDS             complement(3659..3823)
                     /locus_tag="PC503_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528410.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(4365..4697)
                     /locus_tag="PC503_002445"
     CDS             complement(4365..4697)
                     /locus_tag="PC503_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2528411.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(4941..5582)
                     /locus_tag="PC503_002446"
     CDS             complement(4941..5582)
                     /locus_tag="PC503_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF2528412.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(5563..5856)
                     /locus_tag="PC503_002447"
     CDS             complement(5563..5856)
                     /locus_tag="PC503_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2528413.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            6249..6308
                     /locus_tag="PC503_002448"
     CDS             6249..6308
                     /locus_tag="PC503_002448"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2528414.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            complement(6824..7576)
                     /locus_tag="PC503_002449"
     CDS             complement(6824..7576)
                     /locus_tag="PC503_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2528415.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(7635..9290)
                     /locus_tag="PC503_002450"
     CDS             complement(7635..9290)
                     /locus_tag="PC503_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528416.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(10563..11642)
                     /locus_tag="PC503_002451"
     CDS             complement(10563..11642)
                     /locus_tag="PC503_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2528417.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(11726..12382)
                     /locus_tag="PC503_002452"
     CDS             complement(11726..12382)
                     /locus_tag="PC503_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528418.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            12704..12910
                     /locus_tag="PC503_002453"
     CDS             12704..12910
                     /locus_tag="PC503_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528419.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(13063..13491)
                     /locus_tag="PC503_002454"
     CDS             complement(13063..13491)
                     /locus_tag="PC503_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2528420.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(13967..14905)
                     /locus_tag="PC503_002455"
     CDS             complement(13967..14905)
                     /locus_tag="PC503_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2528421.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            complement(15419..16231)
                     /locus_tag="PC503_002456"
     CDS             complement(15419..16231)
                     /locus_tag="PC503_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2528422.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLVEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(16257..16886)
                     /locus_tag="PC503_002457"
     CDS             complement(16257..16886)
                     /locus_tag="PC503_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528423.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            complement(17230..18885)
                     /gene="ilvD"
                     /locus_tag="PC503_002458"
     CDS             complement(17230..18885)
                     /gene="ilvD"
                     /locus_tag="PC503_002458"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF2528424.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(19209..19508)
                     /locus_tag="PC503_002459"
     CDS             complement(19209..19508)
                     /locus_tag="PC503_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528425.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            19768..20448
                     /locus_tag="PC503_002460"
     CDS             19768..20448
                     /locus_tag="PC503_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2528426.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            complement(20558..20815)
                     /locus_tag="PC503_002461"
     CDS             complement(20558..20815)
                     /locus_tag="PC503_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528427.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            21364..21735
                     /locus_tag="PC503_002462"
     CDS             21364..21735
                     /locus_tag="PC503_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528428.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            complement(21732..21872)
                     /locus_tag="PC503_002463"
     CDS             complement(21732..21872)
                     /locus_tag="PC503_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528429.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(22537..23433)
                     /locus_tag="PC503_002464"
     CDS             complement(22537..23433)
                     /locus_tag="PC503_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2528430.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            23574..25001
                     /locus_tag="PC503_002465"
     CDS             23574..25001
                     /locus_tag="PC503_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528431.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(25197..27791)
                     /gene="clpB"
                     /locus_tag="PC503_002466"
     CDS             complement(25197..27791)
                     /gene="clpB"
                     /locus_tag="PC503_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF2528432.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNNFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(27828..28424)
                     /locus_tag="PC503_002467"
     CDS             complement(27828..28424)
                     /locus_tag="PC503_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528433.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNLDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(28441..28845)
                     /locus_tag="PC503_002468"
     CDS             complement(28441..28845)
                     /locus_tag="PC503_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF2528434.1"
                     /translation="MDKTLKKDLNQEYTESKSLIMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            29212..29586
                     /locus_tag="PC503_002469"
     CDS             29212..29586
                     /locus_tag="PC503_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2528435.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            29583..30446
                     /locus_tag="PC503_002470"
     CDS             29583..30446
                     /locus_tag="PC503_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528436.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            30446..31084
                     /locus_tag="PC503_002471"
     CDS             30446..31084
                     /locus_tag="PC503_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2528437.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT        10641 a         4844 c         3416 g        12213 t
ORIGIN      
        1 aatataaaag acagtaattt atctatagtg ttacttatat tttatatata tggctatttt
       61 tcaacatttt acaatatata acatttattt ttttaacttt tgtcagtaaa atgtcagcaa
      121 aacactttat ccacaatttt tatataagtt ttccacaact tatcaccaat attatccaca
      181 taaaaaaggt agcacttata ttattagcta ccttttattt attaatcttt atatttccag
      241 ctttttatcc aacttcctat ttctattatt ttttcttcag ttatttcttc tccatcatgt
      301 aattttgaaa ttaattctga taaaggattg ttatgtaaac ctctaaaaac tctttttccc
      361 tctattttga gatattctct ctcttttatt aatactgtat agtgtacatg cctcccaatt
      421 ctctatgata ttaaaaaacc ttttttggtt aatctagcta aaagtataat tgtagttgta
      481 tgcttccaac catatgtttt ttctatttca tctgcaacat cttttgatat tacagtttta
      541 taaccagtat gccatatgca tttcataatt tttaattctg tatctggtaa ttttttattt
      601 agcataatat attccttctt tcaatttatg tcacttcttc aaatttatct agcttaaatt
      661 ataataggag ctttttagaa caaaaactat atttaatttt taccaggtac tctacgtgtt
      721 tagtctgttt ttaagtgtaa aataatgttc atatctataa atttatttaa ctttcaaaca
      781 atcctgttga ataataacta attctattgt attattttag ttgtagaata aaactaaatc
      841 ggcaaaacta gagaaattta gtgacgcaaa gctataggga ctaagactta tataaatatc
      901 ttatgagtta tgtcagccag ttgccaaaga gatagtgttc tttttgtttt tatgaaagtt
      961 ttttaggggg ataataattt atatgtttgg aaataaaatg gataaatgta cacatgtatt
     1021 gactgcttat attagcagtt cgtatgatta ttgtaatttt ttagatacac agttagatga
     1081 ttttatatta gagtacggag aaaatgtagt agagtcttgt ttacaccaag taatggtatt
     1141 ggtaagtaag tataattaga tagacattga tttctagaaa acccttttta gttttatcta
     1201 catttatatt aatatatagc aatgtaaaac gtttaaatat atttttaata ttaagaataa
     1261 ttaaaatgtt aactaaaaaa tataattaag tagacatttc tattaatcta tgatacaata
     1321 gtatttgtgg taatacacaa ttaaatcaag tatatcttga tataggttaa taggagtatt
     1381 tttaatgaat aatggaatag tgaaatggtt taataatgaa aaaggattcg gttttatatc
     1441 aatggaaggt agagatgatg tgtttgctca tttctcagct atacaaactt caggatttaa
     1501 atcattagaa gaaggtcaac aagtaagctt tgatatagtt aaaggtgcta gaggtcctca
     1561 agcagaaaat ataactatat tataatatat agatttttcg ggaaagactc tttttagagt
     1621 ctttttttat tgttaatata tgtaagataa tcattggtga agtaaataag gtatattgag
     1681 taatgttctt gatagtttat atgctaatga atttcaaaaa aataagcact cctataaaaa
     1741 gagtgctctt aatgtaaata taaaccttca ttggtccagc ctaatacccc gtattctcca
     1801 agttctaact attttttata tacattatca ctttcatcca tatctaacac aattatttct
     1861 tctttagaat caatttgtaa aatatgagga ctgtgtgttg tgacaattat ttgtgttttt
     1921 aggagaattg cttttaatgt aataaaaatt ttacatacca catagttgat ataaaactat
     1981 aataattaca taagattgta ataataagac ttatctttac ataccacata gttgatataa
     2041 aacaatgaaa ttaacataca agagactaag acaattaaaa tctttacata ccacatagtt
     2101 gatataaaac cccaaaataa acttagcatc tccaatgttt acacatatac aatgctctta
     2161 aaattgcagt gaacgcgcaa tagtgcaatt gataatactt attatatatt ctcaatgcct
     2221 tatatttcaa ctgctaaacc tcaatttgtc acaaatatcg ctcactgcaa aatttctata
     2281 tttttattat atcataacat ataattaata ttttcaatta atttttacat ttaattatgt
     2341 ttaaattcta taataatgca actttaatgt ttctttctgg aactaatata aaaactattt
     2401 cagaaagatt aggtcatgca gatataaaaa taactatgaa tagctactct cagtttttag
     2461 aagagatgga cagagaagca tttgaaaatt tgagcaaaat actatttatt atattttaaa
     2521 gaagatgact tattcaatat ttgatgctag aatataatta ataaaaattt aattataggt
     2581 gattgtatta tgaatattat taaaagcata actttactct taacattatt aattgtgata
     2641 ttaatgacag gctgttcccc aagagaaagt gctagtgaag ttgcaaaaaa atatattgat
     2701 aagatgaact ctggtgacta tgaaacagca tatagtttat taagtaaaga tagtaaaaaa
     2761 aaaattagta tagaaaatct tgaagaattt caaaatattt tagttagtac aaaaagaata
     2821 attagttata aaataggtaa agaaaaaatc ataaaaaaat ataaacatga tggaaaagaa
     2881 tataaaaatg ttgttaaatt agaagaaact tttaatataa aaaaccttct ttataaaaaa
     2941 gatgattctc taaaagtaaa tagatatttt gtagttgaaa ataacaaata caagctatta
     3001 ttgtatgaaa gtttcaaaaa agaatttggt attaatagta tggaccttgc tcaacttaag
     3061 cttaatgatt ttggactaaa atactttaaa gaagttgacc ttatactaaa aaaagctatt
     3121 gctattaatc ctactgattc aaagctttat tatgcccaag catgtaatta tatgaatttt
     3181 gatggatttc ctggttattc agatacaaca tataatgctt tagattcaat taataaatct
     3241 ttaaagtatt tagataaaaa tgattctgac tacaaaaaaa atgcaagtaa tatatataac
     3301 ttaaaaggag ttattcttat gtttcacaaa agatttgatg aagcacaaca atatttaaat
     3361 aaagccttat actttaacaa agataatgaa gacccaaaat ataatctaaa tacaataaaa
     3421 aaacatctaa actagatatt taatttttga atttataaaa tattttttta tgtataattc
     3481 agcactgaat cataatttct actaaactaa ttacaagttt aaattataaa gacttatttc
     3541 tatataaata ttactctata acaataagtt tcttatttaa attttaaaat attatctaaa
     3601 aatcataaaa aagaaggtat aaagagctac cctcaagctc aatatacctt ataaatatct
     3661 aaacttcatt ttttactaat ttttctatat ctttgataat atgttcttta gatttttttc
     3721 cagctatggc atcaaaaatt gcaacagcct ttttctctcc aaacttttct gctacatcat
     3781 taaagtctaa aaatctaaca ctttcttttg gtttaccaaa catataacac ctctcataca
     3841 tttttatata tttattataa cttctataga cttatttttc accaataaac gttagacaaa
     3901 ttagtccctt tattttttta aactagcttt accttcaaaa ttcttaacaa aaacagttta
     3961 ttctactcta taaataaaaa tagacaattt aatttgtagg aaactgataa tagaatacag
     4021 taaataaaac tttgtttaat ctatctgaaa aagttatcta ttaaaactgc tatgaattta
     4081 taaagaatat tctagttcat aaaaatacaa atatgtaaat ataatcacct taatattcaa
     4141 tttatttaaa ataaaaaatg tataaaagat ttaataatga caatatacta ttctcaatac
     4201 aatctatgat gtaaataatt taaaactact atattattta aaaatttata tttatatatg
     4261 caattctaaa aacttaataa gaagtgaact tagaaaataa agcttaattt caaagactta
     4321 aatagactat tattattagt ctaaataaac tacgtctatc aaaattatat attaaattct
     4381 tctaaaattt ttattgcaaa tcttgcgttt ggatatgtaa tagacccgcc accaattaca
     4441 cctattttta tagcttctat aatttcatct ttacttgctc cagaattaat acaaccctca
     4501 atatgataac aaatacactc atcacatcgg cttaaaattg aaatagctag tcccattaat
     4561 tccttatttt ttttgcttat agccccttct gaataagtct tatcatcaag acttccaaat
     4621 actctaaaaa actcatctgt ttcgcttaat tttttattgt aaaatcccct atattctttc
     4681 atttctctag tattcatctt ctacctccta tgtttttctt ataagaatat cacaccgtac
     4741 ttatattttc aatattaaat acaaattttc attttatgtt cattagccta atttatatta
     4801 ttttttgaaa tctcaataag ttatcatata agtaagattt tttcagaact aaaatagaaa
     4861 tcttagtaat ttctttatta tctatctcag ttctgaaata tattattctt atccaaacat
     4921 tattatagtg attaattata ttagttattt ttacctgaaa ttttatacat caaataagaa
     4981 tatataaatg gtagtattac aattacaaag attacaaaga tattataaaa aggaatatta
     5041 ataaatgcat taataattaa taatattcca ccaataagcc aaatccatcc agctaaatgg
     5101 tgtgtcttat tccaattatc ttcatcatta agagtccatg gtaaaattat tcctactgag
     5161 taatttcgtt tacatttagg aagatagttt ccaaataaaa taactattat tcctaaaatt
     5221 aatcctgtat aaaaattaga ctccaaacta actcctgttg aatataaaac catcattatt
     5281 tgtataatta ctgaaagtat agcaactccc cattttgata aattttgtat aacatttgaa
     5341 aaattagctt tcttaggctc attctcaagt ctaaaccatg tatacaaatg gatacatagc
     5401 attaacaatg gtacaccaaa agctgctata acctttggag cataattatc tggatttcca
     5461 taattatcaa aatgaattgc aacttcattt ggtaatctat tataaaaata tattgataca
     5521 ataaatggta taaaacatat taaagtagat aaaataaatt gtttatttat cgcttttttc
     5581 attatctttt tctcccttct ccataaattg tgaaaaccaa agcatgacct cttcgaaaac
     5641 tgaaatattt atttcgtaga aaataaagtt cttatacttt gtttcaaata tgagtcctgc
     5701 cttttttagt tgagatagat gataagaaat tgtagcattc gtcatattaa atttttcact
     5761 aatttctcct gctgacattt tattctccct caacataacc aatatttctc ttcttatagg
     5821 gtctgaaaga gctttgaatg tttctggaaa ccccaacacc atcacctcgc tatttagaat
     5881 ttcatctaaa tagaatataa cataacatcc attttatttc aatagctatt tagaaatttt
     5941 tctaaatagt tatttctaaa tatttattga aaatttttat attaagattc tcaatttact
     6001 taagtcgctt ttatttaatc ttactttatc taattttttt aacttaacaa aagtgtattg
     6061 caccataatt gttaaagcaa aaacctaatg attgaggtac ttatatatat aacaatactt
     6121 ttaattttaa attaaaagta gctaaaccca atttaaaaag tagttaagtc ctatttaaat
     6181 agaaaagaat gaaacgagaa atatactgta taaaagtaca taaaaacatc tactaattag
     6241 atacaactat aacagaatat atttattatt ataataacaa aagaataaaa aaaattaatt
     6301 tagcataacc ttgttaaata tagatttgaa tatgaattta aagttatgta aaattaaaaa
     6361 tacaggaatg aaaattccat tcctgtataa aatctaactt ttgagtctca gtacaatctt
     6421 attttgagac aatctttttt gttttatatt ttcttatatt taaaatataa cgcatatctt
     6481 atgcaacata ttcatatttt tctttatatt ctttcatcgc atcattccaa gcgtcttgta
     6541 ctgttacacc tcttttatta gcaatttttt gtgccagttc aattatcttc atagctcttc
     6601 ttgatatgtt cataaacatt cctcctacaa attaccatat atttcatata tataaatcaa
     6661 ggttatattt ttatgatata taatccttct attgtaagat tacagtttat atgtgtatta
     6721 tatatgaact atattagaag ataattagaa tttttataaa gctatatgat tagattaaat
     6781 ataaaagctt tacaattact tataaattta aaaagtctat aagctaaact aatgtttgat
     6841 ataccaattt tacgaccata aataatgcca ttactaaaaa tattggtttt atcatctttg
     6901 aacctttctt tatagcaact ttagcaccta cataagctcc cattatcatc actaatgcaa
     6961 acactatagc aattttataa tctacttgac catttatcat gaataataac aatgaagtta
     7021 tattacttgt taagtttaat atttttgtat ttgcagaagc atgtaaaaaa tcatatccat
     7081 atatttttat aaatccaaaa gtcaaaaaag ttcctgtacc tggaccaaaa aaaccatcat
     7141 aaaaacccat tataagagcc ataagcatcc ctaatcttaa atttttctta ttaacagctt
     7201 caaaattatc ttcttgacct aaatttttag aaataaaggt gtaaatagcc actattaaaa
     7261 tcataaccac aaccaaaaca tttaatatct cttcacttat tgataataca catctcacac
     7321 ctagaacact accaataata gtaaatggta ctaatttttt taaaaggttg ttattaattt
     7381 ttccagactt tgcatatcta taggcactac ttatacatcc tgctgatgct gcaaatttat
     7441 ttgtaccaat ggcaagatgt actggcactc caattgccat aagaacaggc atgcttataa
     7501 gtcctcctcc tcctgctata gaatctacaa aagcagctaa aaacccccct atacataaaa
     7561 aaataactga aaacataaaa ttcctccatc attctctttc aatttttctt acaatatata
     7621 ttatataatc ttatttaata cttattatcc agcatattct ttctatattc atttggagtt
     7681 atactattaa acttcttaaa tatttgtgaa aaataactac tgttattaaa acctactttc
     7741 ttacaaatat cactaatact catgcttcta tctaacagat attttttaga ttcttctatc
     7801 ctaagaagat ttatatactc agttattgaa actttatttc tttcattaaa aatagaactc
     7861 aaataatttg gacttataaa aaaaacatct gatatactat tcaaatttat attttcttta
     7921 taatattttt ttatatattc gtttatattt tcaattagat ttcctttatc ttttctccaa
     7981 aatgctctat tcttatcaat acactctttg gaaaattcaa ataatacatt ccataaatct
     8041 tcatcactgt ttacaagtga tattttttta ttatatttat ttcttaaata agatataagt
     8101 tttaaatcct ctaaatctct aagcactgtt ctagacaata caaatatcat ttcctgaata
     8161 gtatctctaa catcattata tcttaatttg tttgtatcta ttagattata aacaccttct
     8221 aaattcatat ttttaatttc tttttcaata taaagttcta attcaaaggg atattctttt
     8281 gaagaattat tgaacatatc tatcggatta ataatatact cttcttctaa taatctacta
     8341 tttgcttttt taagtgcctc ttcaagtctt atattttctt ttctactctt caatatctcc
     8401 tcatctttta tactaagttg attttcaaaa aaattcctct tagctatttc ctgaataaat
     8461 tcagacatca ttaataaatt ttcttttaat acatataatc tacttttagg atttaatgga
     8521 aattcattgt aaattttgtt tatgtatttt atatcaatac cagaactact tgataattca
     8581 gataaatttt tatctatatc aatagactta tatactataa aattaccaca ttctatatat
     8641 ccaactatat tttcttctaa tactataggt atctctaaac tggaaacacc atactcacaa
     8701 tggtacactt tttcaaagtt atcattattt atgcttttaa caagtttttt agtacactgt
     8761 tttatatttt tacaaatatc gcaaaattta ttttctttct tagtctcaaa tatttcttta
     8821 tactttaagt catatacaga tattctaagc ttcaatatat tagatatttg atttgcaaga
     8881 ttttcaatta tgtttacatt aactaactcc tgtatattgt tttcagaaaa tactataggt
     8941 atttgtctca aactcgaaaa tttatgagga acataagtaa ttaatattac taaatcaatt
     9001 ttaccagtgt ttataatttc atgttctgaa tatggtgggc aataaactat agatgtttcc
     9061 tttatattga cctttttacc atcaattatt tgtattcctt ctccctgaat cacatataaa
     9121 agctgttctt cacttaaatg aaaatgcttt tcttggtagt ttcccggaaa aaatcttaca
     9181 attccagcac taagtctatt gaattgtgtt tttgatggtt cgtgtatcca cataacctct
     9241 ccccaatcaa atttttgtac ttcattattt gactcactaa aatactccat aagctcacct
     9301 cttagttttt gtctaaatat tttttcttcc cttcttatat taaaataata tcatcatcat
     9361 taactttcat tactataaaa tcatcatact cttttaatac tcctgtaatt ttagttgcac
     9421 ttagtttact acaattcagt tttttaatat attgataaat tctataatta cttttttatt
     9481 ttgtaaaatc agtgttttcc caaaataatt atatctataa atgaaagtat ttttactgct
     9541 tacatcaata tatgttatca taattttcct ttttattgca tatataaata actgtatata
     9601 acattgtcca atactatata gaaatacatc taagaaagaa tattattaaa ttgttccaat
     9661 tagtattatt tttcttatag aaataaaaaa actgttggag tcttttagaa aaattatttt
     9721 ttacatacct tttttgctta gatagtctat cttcacagct attttgtata tacactcttc
     9781 tagttcatga ttttatttta atatcttgct tatattgctg aaataattga attcttttat
     9841 ctatcatatt gtctcttata tcacaaacat attgtttctt atatcacaaa aatgaaagca
     9901 ttcttatatc ttcaatatat aaacctgctt tttttaatct tgtaataaat ataggatact
     9961 ctatattctc ttcctagaaa taactaatac cacttatttt tctattatat agaaagtaat
    10021 aaatcttttt cttaataaaa ttcaatagta agtggaataa aattttatat gaataagaac
    10081 attataaaaa tactttatac aatagtcaat aaaagatatt agcttcaaat tatgttaaag
    10141 ttgtattatt taaagtgaaa aaacaaataa aaaagaaata atagtataag tagaaaaata
    10201 tacttaaaac aaggcgaagc ctctcttgta tctaaatcaa gtagagaatt aaatctaaaa
    10261 aagaaaataa atataaaaga tgactcctgt acattacaag aatcatctta tggtttcata
    10321 atcactccat ggtttttaac tgtctgatat aaaggtctca gttcactcat agcatgacca
    10381 ccttttccga ttgctgaccc cgtcacttat ggacaaaatg tccataagtg atagtcctct
    10441 cttaaaaccc tctaaataga tatatctcaa gcaccgcatt gaaaccagtt gctggaaaca
    10501 aactgaagcg ttctggaata gtaaaagaaa ttgccaccat atccacgtta ctgtcctagt
    10561 tgttactttg ctaacttcgg agcgatttcc tctaacaata cgcagtcaaa ttctgccttt
    10621 ttgctaagaa atggcagatg gtctgcatct ggtataaaaa aaatctgttt gtctggcgcc
    10681 actatttcat caaaaaattt cttcgctgga agataggggc tattatagtc attttctccc
    10741 atgatgtagt atacagggac ctgatagtca actccataat ttcttatgtc agcttcttcc
    10801 actaaaaacc gcaatacatc accttgattg tcaatcgcat ttggattgaa aatggccgta
    10861 ttttttaact ctctcaatga ataatacggg gttgccagta tactgattat attgcccaaa
    10921 tccatattta tagaaagccc atacttgctt tggtatgttc ttactgtcat aagagctgcc
    10981 aaatagcttg gaccatattt tgctggcgga tatggtgcaa tagcttccag cgccttgata
    11041 tctttttgct tccctgcagc tttcaccatt tcaagtgtct tttcatagcc cacgcgctca
    11101 ttgtccacca tattaacggt ctgcgcaatc ccaatgtacg cgctgtaatc ctccggatag
    11161 gtttgcacag ccatagttcc cagaactgtt ccccagctat gacctataag gataattttc
    11221 tccttgttga actcttgctt caaatatgct gtcacctcat ggacgtcttg cagaacacgc
    11281 tccgcgctca tggtctgcaa aactgctgcc ggatcgttcg caaagtatgt tttgcctacg
    11341 tttcgctgat cccagttcac cacagtaaaa tcattttccc actcatactg gtacagatgt
    11401 aaaaatggca tcattgaatt accaggaccc ccatgaaccc aaaggatgat ggggttgtct
    11461 gcgttttgtc cccggatata taacgcctgc tgtatgccgc cgatctccac catttccatg
    11521 cggtcgattc caggagcttc tattttatgg cttgtacgta taatcgtggg ggctatcaga
    11581 cgcaaaccgg caaacgccag aacaaaaaca gcaactagta tgcaaagtgt gattaatatc
    11641 attttaagta ccttctttca tgaatttttt tagccataga tatctcctct aacattaaaa
    11701 aaaatatgtt gctattttag ttttgttact ctacctgtcc cattggtttc ctttcataaa
    11761 aaatattaat tgattctata atctcatctt ccaggatatc aactcctatt tgtctcataa
    11821 gaaactgtaa gaattgaaac cgtttacgaa gtgtaggaaa gtccccctga aatacatctg
    11881 tatcacacca aaagttaaag agcagcaaaa ttacctctgc gcattcatct gggaactctg
    11941 tgatgatgct tctatcctct atgccttctc gtaaaacatt tgctaatatt ggtgctagtt
    12001 ttttcaaatt atcctgtgta aatgccagta tgatatgcgg actttctatc gcgcttgtaa
    12061 tcatgttact agattctttt atcacctcat ccgttaaatg ccgcctaact aaacttctaa
    12121 gcttctcttt tgctgtaagt ccatgcattt caccgagcca ttgatttact gtctctatta
    12181 tctgttcaaa gcgcctttcc atgaccacat taaaaatatc ttcttttgaa ctgaagtgat
    12241 gaaaaattcc gccctttgac attcctgaag catcaacaat attttgcata cttgttttgt
    12301 catatccttt ttcagcaaac aactttgcag aaatggtaat gatattttca atagcttgct
    12361 ttggattgtt ctttctagtc attatataac tccttcttat taaaaaccga ctgttggttt
    12421 ttattatata agctattcct gcttctgtca agtaacattg tgtttatggc aaaacaataa
    12481 ggtttggtgg ttagacaggt attaattaga ctaatgcgac tttcccctag atggaaccct
    12541 tggtaaattt gcaatcttta ccggctttga ttatatctgt aagcaaggca ggtatggcca
    12601 cacctgccct gtttgcccct cggatattca ttcctatccc tcctctcctt agccattaca
    12661 ccaaaacgcc gctcattgtc tccaatggcg gcgttttaaa gatatgattt ctcatgctgc
    12721 tgaaatatgc aaaaaatata agatgccctt tattattttt cctacaatag aaaagaaaag
    12781 tattgaagaa tgggttaata ttggagcaaa tatgctttgt ttggcacaag atactacctt
    12841 tatcacttat gttatcaatc aattattatc tttttataat gagattgtac caattcaaaa
    12901 acaacattaa attataaatc taattttata ttaaaagaga ctaatatttt atctatctct
    12961 attaaggata ttttcttatg tatcataata ttagtctctc ttattattat atactgctat
    13021 catcattagt tgctatttat actattttta taatatacaa atttattcag ctaacgtttt
    13081 gcctaattct atacactcat cttttgcttc ttcatttggg tcttccattg ctgtaattcc
    13141 ttctccacca ataattgtag caccagcatt ttgcatacgt tcttcccagt ctctcatcca
    13201 ttcacaattt ccccatccat atgaaccaaa taatccaatc tgtttacctg ataccataga
    13261 ttctaattct gaaacaaatg gctccatata cccctcttct agttgctctg ctcccataga
    13321 tgggcaacct aatgcaaatt tatcttcttc ttttaaatca cttggtttca gtaagctcac
    13381 atctaaaact tctggtgtct taccttttaa cttcacacct tcagccacaa aatttgccat
    13441 tttttcagta tttcctgttc cactccaata aacaatatat attttactca tttttacctc
    13501 ctgtagtatt ttttaattaa tcaatagtta gttatagcta actaacatct aaaaaacaaa
    13561 agatttcttt atctgaaatc tctttatttt tctaaatata gaatatcatg gttgattttg
    13621 aaattcaata cttattgata atatttatca tttatatttt atattcattt tataatatca
    13681 aaacactgta tcgtatttct aatctttcat agaaaaattt ctaacttata gtacttttgc
    13741 atctcttata aatcttttat atgtataagt acatagaaaa acacaccttt tccagatgtg
    13801 ctatctataa tatcgtatat ttatttttca attctaacta gctaatatgt ttataaattt
    13861 tatcacttaa tacctttata cattgatgta aaatcttaca cctaagtaat ttttattatt
    13921 tgtctcgact ctatataata tagctatttt atcatcaaat caaaaattat cttttgctat
    13981 tattcttgta tttataaaga tttaaatata agtatccatt tccttgttcc gttctaggta
    14041 ttccaagcgc tctcgtacat tttattaatt gtgcatacag ttcagcttca tctaaatctc
    14101 tttcaaactc ctctcttgcc cattctttaa ttagtgctaa tgagcctgat acgtatggtg
    14161 cactcatact ggtaccactc ataatagcaa gtttattatc catataagtc gatataatat
    14221 ttcttcctgg agctaccaaa tctattgtag tatttgaatt actaaacttt tcaaccaaat
    14281 agttctcatt tattgcacct acttctatta cctcagcata actggctgga taactatact
    14341 cacttgtact agaatcacca tctccattat tacctgctgc acacactaca gaaatattat
    14401 tttttactgc ttgcatgaca gcatttttta aattcttatc atctttgttt cccccaagag
    14461 acatagatat aatatcaacc ttgttattta cagcaaagtt aatagcatta attatacttt
    14521 gatatgttcc agtaccatct ttatttaatg cttttgctat taataattta caatctggag
    14581 ctactcccat aacttcatta ttataattag atgcagctat aatacccgcc acatgagttc
    14641 catgaccatt aaaatcctca tatatatttt tatttccatt actgtcatca ctaaaatttg
    14701 caccaccaat tatttttcct tttaaaagag gatgagatat atcacaacct gtatctatta
    14761 taccaactac aatattttta ccagtataac cttcatccca cattccccta gcattcattt
    14821 gttttattcc atatgggaat ttattttttg cacctcttag attttcattt atttcatatg
    14881 gaattagttt cattctttta ttcatcatat atcctcctaa aaattttatt gcttataaaa
    14941 atcatgaatt ttattttata ataggtttat aaatcaaatt aaaacctata tctacttatt
    15001 tatatttatg atatattttt tatttttagg agtcatattt tattgtatat aaaataatat
    15061 ttagataact atattaaaaa atacatgttt gcttatatac aaaacttact aaaatgtctt
    15121 taatattttt gtatacaaac attatatttt ttatataaaa agctcataaa aattttgatt
    15181 atattttcat aagttaacaa atgtgggtat aatatgaatt tacaaaattc ctctgtttgt
    15241 ataagtgctt taccaataca acaatatata atcacattga agctatattt gtatttatag
    15301 tagataatgt atcaaaaatt ggttatgaat agtaaaaata ccagttaagc atattttcat
    15361 gtttctattt ttaacattaa atttccaatc ttcatatgta tatttttaac aaaggtgttt
    15421 acttatttaa aaactctaaa actctttcat taaaatcctg tgcttcttca tatgtagcgt
    15481 gtcccaatcc ctcatagata aatatttcgc tttttttaat tttttctact aaatgaaaag
    15541 aagcattatt tccaacaatt ttatcattag cacctcctat aattaaggtt ggacatgtta
    15601 ttttatttaa ttcggaaaag gcattatgtt ctatgcaaga ggtcgcttga ataataaatc
    15661 gtttaaaatc ctttggttta cctacttttc ctaaaaaagg aataaataat tggtattttt
    15721 ttaaatatct ttcagaatag gatttctttg ctgtgtcaat cattaaatca ttgtaattct
    15781 gcttcttcgc catatcaatc caactacaaa taacattttg gatagtatca ttttgctttg
    15841 aagaagtaac tgccaacaca agtttctcaa ctaactcagg ataatcaatt gccagatatt
    15901 gagctatcat tccaccttga gaaacaccca ttacttctgc tttcataatt ccaagttttt
    15961 tcattatatc tgcttggtct ttagccatat cccttgtgga atatttttct gtaatttgat
    16021 tttttctact aaatacataa accttataat cttttgtaaa ttgcttatat ctaaaagcaa
    16081 aagcaatcgc ctgtattttt ccatgtaaag gaaataaacc atctcctaat cctggtaaaa
    16141 taattagtgt cttcttacca ctaccaaatt caatataatt cactgtatta cttcctatca
    16201 tcatttgaca actttttgca ttataaaaca tagtctattc ctcacttttc ctattatcat
    16261 tgtttaaata aatctttaaa tttttgaata ccatactcat caattagagg aatatccatt
    16321 ttttttaaca tgaataataa aaaatccaac ctattacata cttcactgta ttcacgttta
    16381 aataatacag ggtcaagtaa aatatcaata ctaaaaacga gcatttcagc taattcctct
    16441 ggatattcac aagaaaattc tttattttca acaccttgtt taattatctt agcaatattg
    16501 ggtgcaacta cattgttgag attacgaact tcctctatta aagcgaatgg gattttttct
    16561 aaccagctac aatgtaccat ttttctacgt gtgtaatcat tcgcactatg aacaaccaat
    16621 tctattattt tttcatttgc tgtaagggtg tcatcagcaa caagatgctc taaaaaatta
    16681 ttcatttgtg agtaaagttc ttttgtgaca cttctcagta tatcttcttt agttttaaag
    16741 tgatgataca ttgcacctct agatagacca gataaattga taatatcttg tgtagatgtt
    16801 gaatcatatc ctttagacga aaatagtgaa aatgctgatt ggataatttt ttctttacta
    16861 tttttacttt tttcttctct attcatattt ccctcctaaa aacagactgt ctgtttgttt
    16921 tttattatac attttaatat ttattatgtc aagaattaac ttactttcaa tttcttcata
    16981 gttcagaagg aacgaaaagc attccacatc aaacttttaa aaagttgtat tacctcaaca
    17041 aggtctaaaa gatacatctc tatgctgtac tcgtattcct tataatagag atgtattgtt
    17101 ttcaaagata atcaagattt tgctatgttt ttcatacaaa ataaaaagga tacctcatta
    17161 gtgctataac acctaagata tccaattaat attttcttaa ctttttctaa tttacataaa
    17221 tatagtctac tattttaaaa ctgctcctgt atttgctgat gttaccagtt tagcatatct
    17281 acttaagtat ccatgcttta ttttcggttc taaaggttta aattttaatt ttctattttc
    17341 tatttcaact tcatctactt ttaactctaa ttttttgtct ggtatgttta tagaaattat
    17401 atctccttct tcaactagtc cgattaaacc accttccata gcttctggag aaatatggcc
    17461 tatggatgcc cctctagttg cccctgaaaa acgaccatca gtaagaagtg ctacatgctt
    17521 atcaagtccc attcctgcaa ctgctgatgt aggagatagc atttctttca ttcctggacc
    17581 accctttgga ccttcatatc ttataactat aacatcacct ttgtttattt ttttaccaaa
    17641 aatagcattt acagcttctt cttctgaatt aaaaactctt gctggtcctt catgaactaa
    17701 catttcttct gcaactgctg acttttttac aacagctcca tttagagcaa gatttccttt
    17761 caatattgca agcccacctt ggttactata tggattcttt aatgtatgta ttacttcttc
    17821 attttctatt tcacaatttc ttatattttc ccctatagtc ttgcctgtta cggttttgca
    17881 atctaaattt attccattta tctttgaaag ttcgttcatt atagctggta ttcctcctgc
    17941 catatgtaaa tcttcaatat gatgttttcc acttggactt aattttgtta aacaaggagt
    18001 tttttcactt atttcatcaa aaaaatctaa gttaagctct attcctgatt cataagctat
    18061 tgcaggtaag tgaagtactg tatttgtaga accagccatt gccatatcca cagctatagc
    18121 atttttaaaa gcatctattg ttaaaatatc tctaggtttt atgtcgttct taagtaactc
    18181 cataacatac atacctgcat attttgctat cctttttctt tctccagaat gtgacgcagc
    18241 agtaccatta tatggtatac ccatgcctaa agcttctgtt aaacaattca tgctatttgc
    18301 tgtgaaaaga ccagaacatg aaccacatcc aggacaagag ttcatggcta actcttctaa
    18361 ttcttcttca cttactgttc catctttaca tgctccaaca ccctccattg cagagttaaa
    18421 atcatatact tttccatttt ttttacctgg aagcataggc cctccactca caacaatact
    18481 tggtatatta agtcttgcag cagccattaa catacctggc actatcttgt cacaattagg
    18541 tataagtacc aaagcatcaa aaccatgtgc catagccata gcttctattg aatctgctat
    18601 taattctctt gaagccaggg aataattcat tccgacatgc cccatagcta taccatcaca
    18661 tacccctata gcaggaaatt ctaatggcaa accaccactc attcttactc cattttttgc
    18721 agcttctgct atttcatcaa gatgcagatg accaggaatc acctcatttt gtgcatttac
    18781 tatacctatt aatggtcttt caatttcttc tttagtaaga cccattccat acattaacgc
    18841 tctctttgga gctccttcta ttcctttttt tatatcactt ctcataatat tacctctttc
    18901 ttactttttt aaattttcat aatattatta taatatattt ttctattaat taattacgaa
    18961 aattgtaaaa aaatattagc atatactaat gaaaatttat tacgattttt tatcaatatc
    19021 ttacacaatc gtattatata atattatctt ttcaatatat tttataaact aatatatttt
    19081 acaaattgtt gagtaatatt ttatgatata aatcagaaga ggcacttcta taatagaaag
    19141 tgctcaacta tgaataagat taataatata tttgccttag atatatagac ttttataaat
    19201 attaaagatt aatcaaatct gatgtttgaa actttatccc aattaatctt ccttgaatag
    19261 tcttctggat gtgataatct aactatatga gttgaattat catagctgta ataaattgta
    19321 gtagtaccat caactggatt ctttttgtat ccttgataca cagcactatt tggtactttc
    19381 ttttcaacaa agctatatgc agatgaagta tcaatagttt ctattttatt aggaaatata
    19441 aacatataaa aagctactac tataaaaata catatgcatg taatactata ccatttaatc
    19501 catttcataa aattcctcct actttaccaa aatatactat tattatttcc atatatttat
    19561 aatatttatg catacgataa aatttttata tccctaacta tataattgta gaaactttga
    19621 ttatatatat tttttaatct taataatata tttttataaa ttaataaatt tttaagattt
    19681 tattaaaaga tttttaaaac ttacagttta atataaagat agtacttata aaactaaaaa
    19741 cataaatttg aaaggggaca aaataaaatg atatggacat tttattcatt tatttgcgtt
    19801 atattaccat gcttaatata ccaaatagtc gttataaaac gaaaaaattt gaaagttgaa
    19861 aagaatgtaa tgatacattt agtatgggta tatatttttt tattatatat ctatctagca
    19921 cttagtaaag ctggaattgg tagcatatgg gatataggaa ggtatagtgg gctttttaga
    19981 attgatgaaa taaatctaat accttttgac tcagttggca tcttaacata tattttaaat
    20041 ataattatgt ttatgccttt aggattttta ctacctttaa tttggaaaaa ttttagaaat
    20101 attatcaatg tttcattaac tggattaggt ttttcattag caattgaact ttgtcaattg
    20161 tttaacttaa gagctacaga tattgatgat ttaatgatga acacattagg tgctgtttta
    20221 ggatatttta tatgggtagg tgtaaataat ttatttaatc ttataaagaa aaaagatatt
    20281 ttcccatcta tatataaaaa tattattcaa gatgagattg ctattacaat tgatgatgac
    20341 ataagcaaaa aaattacctc tctttacaaa aatgaagcta ttatatattt aatacttgct
    20401 gttttaggag aatttttatt gtttaattgg tccattatac cttattaaat aatttattga
    20461 taaaataagt gtacttcgat atttacaaat atgtaaagcc ctctttcata ctacaaaaga
    20521 aagtgggctt tagttattaa attaaaatgc acactcacta tttagctggc atctgaaata
    20581 ttttattaac attgtatctg actttatttg atgttatata atcatatttt gttccatttt
    20641 caatgaagtt ttgtatattg tccaacactt gtatagctct tgtattattt tcataatctc
    20701 ctatttttac agtatcaatt ttactttcaa atactgcata aacttgacta ccatctattt
    20761 taatttggtt tatctgcatt aaattagttt tatcttgact tctaattatt atcatatcaa
    20821 ttcctccatt tacttaattc attttaattt ctaataaata atattttata attgatttat
    20881 agattattta aatttttaaa cttagtattt tattttttaa tacgattatt tatatcaatt
    20941 acatctctaa taaaaaattt tcttaaagaa tacttttttg ataatacttt gttttatttg
    21001 tagattgcat ttttgaccat tataactaaa ttaaataatc taatgtatta aaacataaaa
    21061 ttatctatgc tactgattta ttttatacat ttggtaattt tacttgcaaa aaattttgta
    21121 catattgttt atatctcaat taaaggtttt caaaactttc tatgtattta ttaattaatt
    21181 cagtttctta tttcaacata ccacctctca tcaaattacc atttgtataa ttcatattat
    21241 acatatacaa atggtaattt tcaatatatt ttattatttt aacctttttt ttttatattt
    21301 ttggtaattt tattttactt tttatcaaaa taacttataa tttcggtaag gagtgatgta
    21361 catatggaaa gtttaggaga tagaatagca aatctacgaa aagaattaga tataaatcaa
    21421 aaagaacttg ctactaaagt cggtataact gaggctagct tgtcacgtta tgaaaataat
    21481 ttaagagaac ctaaaagtga aataatagtt agattagcaa aagcattaga aacatcaaca
    21541 gattatttat taggcgtaaa tgataataca aaaataagca aagaagataa attaatcata
    21601 gagaacttat cagtaagtga aaaaacaaaa aagctcttag aaaaaatata ttctcttgaa
    21661 aaagaagata gagaagctat agaaaaaatg attgataatg cctatttaaa aagattcctt
    21721 aaagaagaga attaattctc ttctttttct ttatacaaaa tctcaagtaa taattcataa
    21781 aaagtaatat cttcactcaa taaatgttct aatttcattc ctatatcttc aattttttct
    21841 ttttttgtaa cagtagtgtt tgacttttcc acatatacca tcccccaaca aacttacgtt
    21901 cttaatgtta gtcagaaatt cccaacaaat ttttaataaa gtttatgtaa ttgtattttg
    21961 attttataaa atatattttg attatccaaa atttccctag ataattatct taattatata
    22021 ataatacttt tattctacag ttgcaataaa aaactcgtaa taataacaaa aaaatctatt
    22081 attgtagaat cttgtatgtt ttttctattt ttatatattt ttcaggatga tttttattat
    22141 aaaatttttt ataaatatat aattttttta tatttatttg actttctttt aattctttag
    22201 gatggattta aattttctat aaaaatcata ctattttagc tgtttacttg cttatttaat
    22261 agttttattt ctttgattaa atatctttca gaatctaagc cagatgtctc aaaaaaactg
    22321 atttataata taatcatttt ttctgctatt cttatttttc caattttagt ttcatattaa
    22381 aatatacttt tcatagacac tacattcttt catactcatt ttcacattta actatacaag
    22441 tagtcttact catttatgta ctatacttta ttaatattta ttaagaaaaa ctcaaagatt
    22501 taaaaatata tattttctat aaagtatatt tatgaattat ttcatatctt cttttaaaat
    22561 aacattacta acttctttat gttcatttct atacttagtt ggagatatat tataattcct
    22621 tttaaataag cgactaaaat aatttatgct atcaaagcca catctcatag caatttctgt
    22681 catatttaaa tctgtttcct ttaaataata tatagcttta tcaagcctga ttccatttat
    22741 aaaatcgatt gtagtcttac ctgttatttg cttaaatgtt ctacaaaagt gatgtgcact
    22801 caagttcaca tgactagcaa gttcttttaa tgtaatttta tccatatatt tttcttctat
    22861 caaatcaaag atacattcaa atttttctaa agaatacttt ctttttataa attcatcttc
    22921 agaatatatt ttatcaatat gacttcttaa taagagtact attaattgat agatattagc
    22981 ttttatagat aactcatatc caacttcttt attgtgatat tcatcaagta tagttgtaat
    23041 acattttaaa atcagagaat cattttgaat taaattatta aatacaatat gatttaaagc
    23101 caatggtgct aagtacttgg tttgtaacaa atcaacttga ttactaaaaa ggaatgtggg
    23161 ttcaatacga atactataga attttaaatt atctgataag ctttctaaat aatgtaattc
    23221 attactgttt gctattacaa tatttccagg cactacctta aaattatcca atccacattc
    23281 aagatatgct ataccatcaa taaaataata tatttgtaga tgctcatgcc aatgtctttt
    23341 aaagtttgct ccttttttaa tgtcatcctt taaaaaaata tctataaagt tttcttgacc
    23401 tttcctgtta aaatatgtat ttttatcctt cattattccc ccctcatcaa aatagtgcta
    23461 attataagca atatagttat tgtattcatt atttcatatc gctattatat aaaatgtaac
    23521 tatcattgta aacattaaca taatgcagtc attataataa ggaggtaata aaaatgacaa
    23581 actcttttaa aaaagatgat aatagaaaaa aaatcacagt tttatttgta gtcattgcca
    23641 tgacttttat ggcaacatta gattctagta ttataaatgt tgctctccca gttcttgcaa
    23701 gcaaactaaa tgtatctcta gcatctattg aatgggtaat agcaagttac tcaattatta
    23761 tttgttcaac actattattt tttggaagac ttggagatat tattggtaaa tcaagagtat
    23821 ttcaagtagg tactattctc tttacatcag cttcattact atgtggatta agtaattctt
    23881 taactttact tatagtttgc cgctttattc aaggaatagg cgcttctgcc tacatggcaa
    23941 acaatcatgg aattatcaca gaactatttc caaaagaaag cagaggaaaa gccctaggga
    24001 ttttagttac tgcagttgct attggaaata tggttggacc atctgtggga ggatttattt
    24061 tgtcaatatt tgattggaat gttatatttt ttataaatat tccaatcggt cttattgtaa
    24121 tctttttaaa tacaaaattt cttcctaata gtaaaaaatc ttcagaaaat atggataaaa
    24181 ctggtgctat acttcaattt ttaggaacaa cattattttt tagtgctcta attagtgctc
    24241 aacaaacagg attactaaat ccatatatat taattgcact attattatca attattttta
    24301 ttatattatt tttgatatta gaaaaaaaac atcctcaacc gcttcttgac cttgaaattt
    24361 ttagaaattt taaattttca ttgaatttaa tttgtgctct tacatcattc atttgtattg
    24421 catcatcaag tattttaatt ccattttatt tacaaagtac tatgaaactt ccccctattc
    24481 aagcaggttt atttatgata ctatcacctt tgattttagc cattttttca cctatatttg
    24541 ggaatatatc agataaaatt aagtcagaaa aaattatttt aattggtctt ctcgttatga
    24601 gttttggatt ctttctaatg tcaagattga aagaaagttc tgcccttatt ttatttgtaa
    24661 tttatatatc gataatatca ataggacaag ctatatttca acctgctaac aatgctttga
    24721 taatgtcaag ctgttctaga agtaagctag gagttgtagg aagcataaat tcccttgtaa
    24781 gaaatttagg acaagttata ggtattacta tttctacaac acttttatat aattttatga
    24841 gtattaaagc tggatatagg gtcaatgatt atgtgattaa taatgataaa atatttgtat
    24901 ttggaatgag aaatgtttat attattgtta cacttgtttg cttaataggt gcaatattaa
    24961 ttggctttta tttatttaaa tataataaaa atgaacaata gtttttataa ttatattcaa
    25021 attatgatta tattataaga aatttactaa aatacttcct ttgagttaaa tttaatttgg
    25081 acatattgac ttaaaaatgt tttattaatt tgataaaata tttcttttcc tatagtttat
    25141 aaataaaaat cagctgagca aaatatttag tatattatgc tcaactgatt cttttattat
    25201 ttaactaaaa cttcaatatt ttcatctttt ccatctataa ctatagtaca tccattatac
    25261 acatctccag caataagttt ctttgcaatt atagtttcta atgtatttcc tatatatctc
    25321 ttaagaggtc ttgctccata tacagggtca tatccttctc tcaccataac atcttttgct
    25381 gaatttgtaa cttcaatagt aatatctttt tcttttaatc tattttttaa atctttcata
    25441 aatatatcta taattttctt gatattttct tggtctaaag gcttaaacat tataatatca
    25501 tctactctgt ttaaaaactc aggtttaaat ctatgcttca tttcattcat tactaaattg
    25561 ttagtagtct ctgttatatt tcctcctgct tctaatagat aattacttcc tatattagaa
    25621 gtcattatta taagagtatt tttaaagtct actgtcttac ctttattatc agtaagtcta
    25681 ccatcatcta atatctgtaa gaacatgtta aatacatcct catgtgcttt ttctatctca
    25741 tcaaatagta ttacagaata aggagcacgt ctaactgctt ctgtaagttg accaccctct
    25801 tcatatccca cgtaccctgg aggaggtcca actagtcttg atacagcatg tttttccatg
    25861 tattcagaca tatctattct tattatatta tcttcactat cgaataaatt tctagcaaga
    25921 gtttttgcaa gttcagtttt accaacacct gtagggccta agaaaataaa tgaaccaatt
    25981 ggttttcttt catcttttaa tcctgctctt gcacgtatta ctgcatttga aactgctgta
    26041 actgcttcat cttgtccaat aactctttta tgaagttcat cttctagttt aagtaatttt
    26101 tctctttctc cttcaactag tttagttact ggtatacctg tccactttga tacaatgcta
    26161 gatatttctt cttcagtaac ttcttctttt aaaagagaat tttcagaacc atcattcata
    26221 ttttcttcgt actgctttat ttgttcttct aacttaggta tttcaccata tttaacctct
    26281 gctgctttgt tgaaatcata ttctctttca tacttttcag ctttaccttt agcttcgtct
    26341 aattgagcct ttaagttttt aatatctaat atttgactct tttctttttc atattttgct
    26401 gtcatttcat catttttaga ttttaactct gctatttctt tttgaatatc atccaatctt
    26461 gatttacttt tatcatcatt ttctttaagt aatgcttctc tttcagtttc taatgtaaat
    26521 aactttcttc taacaacatc taattctgtt ggcaatgaat ctatttcact acgaatcata
    26581 gctccagctt catcaattaa atcaattgct ttatctggta aaaatctatc ttgtatatat
    26641 ctatgagaaa gttttgctgc tgctacaata gcattatcat gtattcttac tccatgatgt
    26701 atctcaaatc tttcttttaa acctctaagt atagatattg tatcttcaac agtaggttct
    26761 tctgcaatta caggctgaaa acgtctttca agagccttat ctttttctat atactttcta
    26821 tattcatcaa aagtagttgc accaatacag ttcaattcac ctcttgcaag cataggttta
    26881 ataagattac ctgcatccat tgaaccttct gttttaccag ctccaacaat agtatgaatc
    26941 tcatctataa acagtataat ttttccatca gaactttgaa cttcttttaa aactgccttt
    27001 aatctttctt caaattcacc tctatatttt gcaccagcaa ttaaagctcc catatcaagt
    27061 gagaatacaa tcttatcttt taaaccttct gggacatctc ctcttactat tctctctgct
    27121 aacccttcta caattgcagt tttacctaca cctggctcac caatcaatac aggattattt
    27181 tttgttcttc ttgataaaat tcttataatc cttcttattt cttcatctct cccaattaca
    27241 gggtctaatt tatttttctt ggctaaatct actaaatttg ttccatatct agcaagtgca
    27301 tcatatgtgc cttctgggtc ttgtgtttct actctttgac tacctctcac ttgtgataaa
    27361 atatttaaaa agttattctt atttatatta tattgtttta atattttacc aacagctgat
    27421 tttgattctg tttccatcat tgcaagcata acatgctcta cacttatata tgaatcttta
    27481 aattctttag aaatactctc tgcctttata agcacctcat ttatttttct agtagctgat
    27541 actccttgtg agtcagcacc ttctccatat acctttggaa gcttatcaat ttcaaagttt
    27601 acagtatttc tcaaagaatc aattgatata ttcatttttt cgattatatt tggtatcaat
    27661 ccatcctctt gattaataag tgctgagaaa agatgaatta catctacttg ttggttatga
    27721 ttttttactg cttcgttata agcctcattt aaactttttt gaactcttaa agtcattttt
    27781 tctacgtcca tataaatccc tccattttaa tattatatcc aaataaatta aattctctca
    27841 tttataatta ttgattttct aagctctaaa agactatcaa gtaaattctc gtttttttgt
    27901 atatcgaaac tcaatgttaa attaaatgtt ccatctaaat taaaaaaatc gaatacttct
    27961 tttgattttg ctattaaata caagtcttca tctataagtc ttttttcacc tattaataaa
    28021 tactgacatt tatctataaa actcttttta aaatcaatag tgtatagatt ttctaaaata
    28081 ttatattgat aaatagcaat attattaaac acttttaata tgtttgaatt tacaaaattg
    28141 taaatttgat tattgttata cagtgatatt tgttcgtata tatattccct aaataaagga
    28201 tgaatgtttt gcttaagttt taaagtaact tcagctggta tttcaaaata aagcttccag
    28261 tacttagagt tatttttttc taaaataaaa gctactttgt tcaaactggt agaactaatc
    28321 tcctttagtg tacaattaaa attatagtgt ctcaaactag ttttttcatt ctcaaataca
    28381 tagtcaaacc actgtagaac atttctatca agttttaaac tcatataaaa accttcttcc
    28441 ttatttacta accttattag gtctttttat ctgattatat tctgctaata aactttcttt
    28501 atcagctcta ctacctttat atgctatatg tggatttatc atatactcac catttttcac
    28561 tctttgtaaa aaatccattt ttttcagctc cgtaaacaat gaagataaag aagtttttgg
    28621 atattcaaat tcacaagata attcatataa tgtttttcta atcttattat ttttatccat
    28681 agagtttatt aattttaatg gaattaaatc cctcttagta tacattcctt ctactacttt
    28741 aatataattc ttaaaacaaa cattcatata cttactttta ttcataatta aacttttgct
    28801 ctctgtatat tcctgattta aatccttttt taatgtctta tccaaattaa atatctcttc
    28861 tcactctcct tatctctaat tgataatata aatatattac aaaaaaatat gtatgtcaaa
    28921 actgaaaatg caaaaagttc accttataag taaactttta tttagctata agctaaactt
    28981 tattattttt ttaatttagt atttccaatt tattggcagg atttttgaac aatatttata
    29041 aattttttaa aaaaatttaa atctatttaa tatggcagac tttcataaaa tacattacat
    29101 ttattaaatg tataatattg gtaattagtt ttttctaaaa tcagttgaca tattatatat
    29161 atatttatat aatgtgtata tactatatat acaatttaag gaggtgtctt attgaatata
    29221 gttattagta attcgagtgg gaagccaata tatgaacaga ttactacaca aattaaaagt
    29281 atgattataa gtggagagtt accagaaggc tcagctcttc caagtatgag actattggca
    29341 aaggaactta gaataagtgt aattactaca aaacgagcat atagcgattt agaacgagac
    29401 ggatttattg agacagttac tggtaaaggc agttttgtat ctagtaaaaa catggatttt
    29461 gtcaaagaag aacaatttcg tttaattgaa gaatacctac aaaaagcagt tgatacagca
    29521 aaaagtagtg atattacata tgacgaatta aaagatattt tatttttatt atataaagga
    29581 gaatgataag tatggatgca ataactataa aaaatttaaa taaaacttat aaagatttta
    29641 gcctacaaga tatatctttt tcagtaccaa aagggagtgt aatgggattt gtaggtgaaa
    29701 atggtgcagg aaaaacaact acattaaaag caattttaaa tttaatatct tatgatagtg
    29761 gaaatataga aatctttggt cttgatagta aaaaaaatga aaaagaaatt aaagagcaaa
    29821 ttggggttgt atttgaggga agcaactttc atgaaaattt aaacactgac catgtttcaa
    29881 aaatcatgag taaaatctat aaaaattgga atgacacatt atttaaagac tacttaaaaa
    29941 aattgagagt accagacaat aaattaatta aggagttttc aaaggggaat aagatgaaac
    30001 ttagtattgc tgtagcctta tctcataaac caaaattatt aatactagat gaggcaacta
    30061 gttcacttga ccctatcgtt cgtgaagaaa tactagatat atttttagat tttatacaag
    30121 atgaagaaca ctctattatc ttatcttcac atattacaag tgatttagat aagatagcag
    30181 actatattac atttatacat aaaggaaaaa ttgtatttag tgaaaataag gatgaattaa
    30241 ttgatactat gggagtttta aaatgtaaac ctagtgattt tgataacctt tcaagagagg
    30301 attattcata ttatcgtaaa agccaatttg gatatgaagt acttcttaaa gataagcata
    30361 gatttatctc aagacatcca aactgtattg ttgataatac gtctatagaa gaaattatgt
    30421 tattttatgt gagaggtgat aaataatgaa aggtctaatt ttaaaagatt tacttaattt
    30481 gaaaggaaat ataaagttta tacttttatt catcattatg tttggcttta tgtcttcttt
    30541 aggagatgga aatgttaata actttatagg tgttattata gttttatgta ctacaatgat
    30601 tgtttcaaca ttttcatatg atgatttgaa taaatgggat agttatgtac ttacaatgcc
    30661 tattaatcgc aatgatattg tattaagtaa atatttaact atgttaatat ttagctttat
    30721 aggtgttctt gtttcactta ttgttagtgt aactattggt tattttaaaa atacacttat
    30781 attaaatgaa acactactta ttaatgcact aatcttatca atttcagtat gttttggtag
    30841 ccttattcta ccacttattt ataaatttgg tacagaaaga gctcgtttat taatgatttt
    30901 atgcttttta gttccaacac tagctttatt agtttttaaa agtattttag aaaatattag
    30961 ttcacctatt tctatagaaa ttatacttaa tacactagta tattctcttc catttgttgc
    31021 tattttacta tttgtgattt catattttat atcatcaaaa atctatagta aaaaagaagt
    31081 ataaaatata ctatatatgt ttctgtattt aagt
//
LOCUS       DAMJWC010000047        30690 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMJWC010000047 DAMJWC010000000
VERSION     DAMJWC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30690
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.047"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..2066
                     /locus_tag="PC503_002472"
     CDS             165..2066
                     /locus_tag="PC503_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2528438.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2069..3112
                     /gene="ypdE"
                     /locus_tag="PC503_002473"
     CDS             2069..3112
                     /gene="ypdE"
                     /locus_tag="PC503_002473"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2528439.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3127..3432
                     /locus_tag="PC503_002474"
     CDS             3127..3432
                     /locus_tag="PC503_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2528440.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3529..3864
                     /locus_tag="PC503_002475"
     CDS             3529..3864
                     /locus_tag="PC503_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2528441.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3896..5218
                     /locus_tag="PC503_002476"
     CDS             3896..5218
                     /locus_tag="PC503_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2528442.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILSNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEGLLDDLGLDF"
     gene            5228..6298
                     /locus_tag="PC503_002477"
     CDS             5228..6298
                     /locus_tag="PC503_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2528443.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIKLIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6303..7490
                     /locus_tag="PC503_002478"
     CDS             6303..7490
                     /locus_tag="PC503_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2528444.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7687..8559)
                     /locus_tag="PC503_002479"
     CDS             complement(7687..8559)
                     /locus_tag="PC503_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF2528445.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8953..9144)
                     /locus_tag="PC503_002480"
     CDS             complement(8953..9144)
                     /locus_tag="PC503_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528446.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9364..10410
                     /gene="cobT"
                     /locus_tag="PC503_002481"
     CDS             9364..10410
                     /gene="cobT"
                     /locus_tag="PC503_002481"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF2528447.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10442..11002
                     /gene="cobU"
                     /locus_tag="PC503_002482"
     CDS             10442..11002
                     /gene="cobU"
                     /locus_tag="PC503_002482"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF2528448.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            11012..11785
                     /gene="cobS"
                     /locus_tag="PC503_002483"
     CDS             11012..11785
                     /gene="cobS"
                     /locus_tag="PC503_002483"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF2528449.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11805..12419
                     /locus_tag="PC503_002484"
     CDS             11805..12419
                     /locus_tag="PC503_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2528450.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12486..12665
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12795..14294
                     /locus_tag="PC503_002485"
     CDS             12795..14294
                     /locus_tag="PC503_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF2528451.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14333..15709
                     /locus_tag="PC503_002486"
     CDS             14333..15709
                     /locus_tag="PC503_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF2528452.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            15710..16681
                     /locus_tag="PC503_002487"
     CDS             15710..16681
                     /locus_tag="PC503_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2528453.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16713..17783
                     /locus_tag="PC503_002488"
     CDS             16713..17783
                     /locus_tag="PC503_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2528454.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17785..18672
                     /locus_tag="PC503_002489"
     CDS             17785..18672
                     /locus_tag="PC503_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2528455.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18660..19292
                     /locus_tag="PC503_002490"
     CDS             18660..19292
                     /locus_tag="PC503_002490"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF2528456.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19301..20527
                     /locus_tag="PC503_002491"
     CDS             19301..20527
                     /locus_tag="PC503_002491"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF2528457.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDNLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20524..21132
                     /locus_tag="PC503_002492"
     CDS             20524..21132
                     /locus_tag="PC503_002492"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF2528458.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21122..21697
                     /locus_tag="PC503_002493"
     CDS             21122..21697
                     /locus_tag="PC503_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF2528459.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21690..22442
                     /locus_tag="PC503_002494"
     CDS             21690..22442
                     /locus_tag="PC503_002494"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF2528460.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22426..23547
                     /gene="cbiG"
                     /locus_tag="PC503_002495"
     CDS             22426..23547
                     /gene="cbiG"
                     /locus_tag="PC503_002495"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF2528461.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23544..24269
                     /gene="cobJ"
                     /locus_tag="PC503_002496"
     CDS             23544..24269
                     /gene="cobJ"
                     /locus_tag="PC503_002496"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF2528462.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24266..25018
                     /gene="cobK"
                     /locus_tag="PC503_002497"
     CDS             24266..25018
                     /gene="cobK"
                     /locus_tag="PC503_002497"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF2528463.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            25037..26515
                     /locus_tag="PC503_002498"
     CDS             25037..26515
                     /locus_tag="PC503_002498"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF2528464.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26545..27450
                     /gene="hemC"
                     /locus_tag="PC503_002499"
     CDS             26545..27450
                     /gene="hemC"
                     /locus_tag="PC503_002499"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF2528465.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27440..28939
                     /gene="cobA"
                     /locus_tag="PC503_002500"
     CDS             27440..28939
                     /gene="cobA"
                     /locus_tag="PC503_002500"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF2528466.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28956..29921
                     /gene="hemB"
                     /locus_tag="PC503_002501"
     CDS             28956..29921
                     /gene="hemB"
                     /locus_tag="PC503_002501"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF2528467.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30074..30652
                     /locus_tag="PC503_002502"
     CDS             30074..30652
                     /locus_tag="PC503_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF2528468.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12428 a         3063 c         5671 g         9528 t
ORIGIN      
        1 attgaactat atattttatt attataaaat atttatatta aattgtggaa ttaaaatata
       61 ctaggatata aaattcttaa ataaaaagaa aaggttgttt ttataaaaaa tattttttat
      121 accactttaa aaaacacaat aataacactg agggaggtgg ggatatgaga gaacgcatta
      181 ttcttgaaac attaaaaaat agtagtggtt atctaaacat agattatttt gcagataagt
      241 tgggggtatc tactcgaact atcagaaatg aaataaaaaa gatagaaact ataaaagaat
      301 gtaatggttt taaattagaa tataagtcta aattaggata tattctaaat attaaagacc
      361 aagataaatt cgagcattat ctaagaaact taccctcaga tttagttgaa aatccagaac
      421 aacggttgga gtctataata gtagagcttt tagtaaatga aggttataaa actatagaac
      481 agttaagtaa aaaatttcta gtaagttcat cccaaataaa aaatgattta aaaaagatag
      541 atgaaaagat aaaggataca gaattaaaac tagagcgaaa ggctcattat ggaattaaaa
      601 tagaaggttc tataaaagaa attcaaagta tattggtgga tagttatttt agagggaata
      661 gaaatataac agagtacagg aataagttta tagataattt aaaattagct aatattagaa
      721 gtacaataaa aaatgtactt aatgaacatg atttagaagc aaatttaaca gaacttgagg
      781 aaatattagc acaaattatt atattgtata taagagttag tatgagagta gtgggaaatg
      841 ctagcgattt aaaattatat acagaagatt taattataga taaattatta gataaaattt
      901 ttagagataa aaaatataac cttaattatg atgaaaagta ttatttaaag gagcttataa
      961 aactaaagac taaagataag aaagccacta taaagaatat tgataagaat aaacttcaag
     1021 atattatgtt cgaatttttt agagagatag ataaaaaata taactctaat tttttagaag
     1081 ataaagagtt ttttaactta ttttacttac atattgcatg tttaatagaa cgtataaaga
     1141 agaaccacaa gataataaat cctttttcag ttaaaataag tcaacagtat ccaactgttt
     1201 ttaatttatc tattcaattt tcaaaaatca tagaaaatga gtatcatata aaaataagtc
     1261 aagatgaaat agggtttata gctactcaca ttgctgttcc ttttgaaaag agagaagaag
     1321 ctaattttaa taaaaaatat aaaatagcaa taatatgctc ttctggtgga ggtagtgcat
     1381 ttttgataaa tttaagactt aaagaaattt ttccaaatgc tgagataaga aatttttcat
     1441 tactagaaga aaaagctgta atagaatttg caccagattt gattttttca ataacaaatc
     1501 ttttatttga aataaatgct ccagttatac ttataaatga aattttagac gaattggatt
     1561 atttagatat taaagaaagt gttagatttg cagaccatat aggaaatata tcaagcccaa
     1621 aacaatatat attaggtcta tttgataaga atcactttag gtgtataaaa gataaagcta
     1681 agtataagga tatccttgat agtatgtcaa aatgtatagt tgacgaggga gcttgttctc
     1741 caacctatcc caaagatgta tgggaaagag aaagttattt gagtactatt tatacaaatg
     1801 gggtggctat acctcatcca atcgagatga caggaaacaa aaatataata tcagtagctt
     1861 tgatacaaac tgatattatt tatgaaaata gggtgcctaa aattattttc atgatttcat
     1921 taataaaggg aaatttagaa cttcataagc aaatatctaa atatttaagt aagattatgg
     1981 caaataagga tatggtagac atgctaaata agtcacaatc ttatgaagag tttatgtata
     2041 agttaaaaat ctatctggga ggttagacat gaatatagag ttttttaaga ggttgtcaga
     2101 agcagatggt atagcatcta atgaagaaga ggttagacat gttttattgg aagaactaaa
     2161 agcttatagt gataaaatta tctgtgatgg gctagggagt atcatctttt ctaaaataaa
     2221 agatgagagt gcaccaaacg taatgatttg tgctcatatg gatgaagttg gatttatggt
     2281 gagaagtata gacaaacttg gtatgattca cttaataaca ataggaggag taaaacctct
     2341 tgcacagttt gtacaaaaag ttagaattac aacaaaagaa gggaagaaaa tccccgctgt
     2401 cataaatgct acatataata atggtaaggc tgaaaatata tatgcagata ttggagcata
     2461 tacagaagaa gatgtatata acctagggat taatgttggg gatatggtaa catatacaac
     2521 aagctttgag gaatttactt taccagaccg attagtggga aaggcttttg atgataggat
     2581 aggatgtttt gtgatgggag aagttttaaa agaacttagg aaagaaaatc taaattgtaa
     2641 tattcacttt gcggctacaa gtagtgaaga ggttggaata aggggagcaa agacatcaac
     2701 acagttaata aatccagata tagtatttgt aatagatgta gcatgtgcta aaaatgagtt
     2761 tgtgagagac tatacaaata agaaacaaat tgataaaggt gtaatgctaa tgcatagaga
     2821 taggactcta gtccctagta gaaaaatgat agattatgta atggaaattg ctgataaaaa
     2881 taatatacca cttcaacatg atatgtttga atcaggtggg actgatggag gagaagcaca
     2941 tctcgtaaat gaagggaaac cttgtgtagt aacttgtgta ccagttagat atggtcattg
     3001 tgcattttca atagtaagta ataaagattt ggagaacatt ataagattgt atacacagtt
     3061 aattttaaat tttgatgaag aacaatataa acatataaga aattttatct aaaggagaat
     3121 aagaaaatgt caacagaagt acaaataatg gaacttatat caactgcagg agagagtaaa
     3181 tcgaaagctt ttgaggcttt aaaaaaagtg aagtcaaaag attttaaagg agcaaaattg
     3241 ttaatagagg aggctcgtaa aatagatatt gaagctcaca ggatacaaac agaattaata
     3301 actcaagatt taaatgaaga tgttgaaagt ccagcaatga gtcttttaat ggtacatgct
     3361 caagaccact atatgacttc tcagctagca aaagacttga tagaggcttt gatatattgt
     3421 cttgataagt aattgtaata tagaaataga ttatttatgt aaaaattctt ttaaaagttt
     3481 agatgctttt aagagataat aaaaatacaa actttaggag gaattattat gaaaatatta
     3541 ttatgttgtg caggtggatt ttctactaat atgttaatgc aaaatatgaa aaaggtggta
     3601 aaagagagtg ctaaactcaa tgaaaaagat tttgagttta cagctatacc agcagattca
     3661 atagaaagtg aagttgatga ttgggatata gtacttatag gtcctcaaat agctcacaaa
     3721 atagacttct taaaaggaat attagagcca aaaaataagc cttttgcagt aatagataaa
     3781 gatgtatatg gaaaaatgga tggagctaca gttatgaagt tggcattaat aacttataag
     3841 aaacatcaat tagctcaagg ataataaaaa taatgaggga aaagggagat tagatatgtt
     3901 ttcaaaattt gaagcattta tgaatagagt atttatgcct ttagctcata aggttgacaa
     3961 tcaacgtcac cttggttcta taaaggctgg tatggttgct atgacaccat tcacaatatt
     4021 aggaagtata tttgcaatac ttccagcact tccaaatatg cttggagaaa ataatccaat
     4081 aagcaaattc atacttagca attcagcaat attggattta ccagtaagtc tttccatagg
     4141 tttaatagga ttatatgctt gtatgtgtat tgcttttaat ctggggaact actataaatt
     4201 atatatacca ggttgtgttg cactatcaac tttttctttt ttattcctag tagcctcatt
     4261 tacaccagat ggagctttag aaataggaaa tttaggagct aaagggctat ttacaggtat
     4321 gatagcaggg cttggttctg tggagttata taatttttgt aataagaaga atatcacaat
     4381 aaaaatgcca gaaaatgtac ctgattttgt atctaggtct tttgaattaa tacctactac
     4441 tataatagtt tgtggaactt ttatagttgc tcgttttatt tcattaaaag tatttggaga
     4501 attacctcca cagatactta ctcaattttt atctccatta gtaggaagta tggataaccc
     4561 atggtcagtt cttgcactta actttgctat atgtactata ttcttttttg gaatacattc
     4621 atcagtattt agtcctataa ctagacctat aatgattaca tttatagctg aaaacatagc
     4681 agctatgcag gctggagaaa caatacctca tttctttaca gcaggagctt caagtgcatt
     4741 ctttggattt acaggatgtg gaattagtat aggttgtgta attgcatgta tgttatcaaa
     4801 aaatgcttcc tataagaaga ttggacgtgt atcattattc cctgcattat ttgggataaa
     4861 tgaaccaata ttatttggag caccgataat attaaatcca ataatgttta taccacatgt
     4921 atttggtgga gctataatag gtacactacc aatgtttttt atgcactggg gatggttagc
     4981 aaagccagta tttgaccctc catatgtagg ggtattctta gaaggatttt taactaatgg
     5041 agattggcat tctatattag caaatgcatt gcaattagta ttagcagttt tattatattg
     5101 gccattcttt aaaataatgg aacgtcaaca aaataataaa aaacaaaaag aagaaactaa
     5161 gaatatattc tctaaagaag aagaaggctt attggatgat ttaggattgg atttctaata
     5221 ttttgttatg aataatacaa tggagagatt agtatcctta atctataaaa gaggtgttga
     5281 cgctcttttg attaaagcaa aaaatactaa aagatatata ggagctttat caggtagtgg
     5341 tgtatatgtg cttgttacta aggataaaaa ttatcaaatt ctagatggca gatatattga
     5401 tgaagcagat aaaaaaacga ctggtttcat aaaaaggatt gtatctcaag gttcttatat
     5461 accaactata attgagttat taaaagaatt aaatataaaa aagttagcaa tagaaaacca
     5521 agctatgagt atacaagagt atctttcact aaaaaatgaa ggttttgaaa tcaatttaat
     5581 aacaaatgaa ttatggaagc taagggctat aaaatctaaa gaagaaatta aacttattaa
     5641 aaaggcttgt gagattacag atgaagtatt tgatgaggtt atttctgaaa ttaaaaaaga
     5701 tatgactgag ctagaagtat cagctctaat tcagtatcat gcattaaaaa aaggtgcaag
     5761 tggaatgtct tttgaaacaa tagtggtatc aggagaaaga ggtgcaatgc cacatggaag
     5821 acctacaaac aaaaaattga aagtgaatga agctataaca atagattttg gtgttgttta
     5881 tcaagggtat caatcagaca tgactcgtac aatatctata ggcaaacctc ctaaaattat
     5941 taaagagata tatgatgtag tattggaagc acaattatct gcaatagagt caataaagga
     6001 aggaactagg gcaagtgatg ttgacaaagt ggctagaaaa attatagata aacatggatt
     6061 tggcgaatat tttaatcatg gactgggtca tggtataggt cttggagatg gtgaagttcc
     6121 cactttaaat ccaaatagtg aagatatatt agtggaagga atggtaatgt cttgtgagcc
     6181 aggtatttat attccaaatg tagggggagt tagaatagaa gatgatattg ttataataga
     6241 tggaaaaggt gttccactca ataagacatc caaagagttt ataatattag gagagtaaaa
     6301 ttatgaaata taattttaat aaagtattaa atcgtaaaga aggaaattgt agaaaatgga
     6361 gcaaccatgt gattaaagaa aaatttggct taaatgaaga tgcaattcct atggatttag
     6421 ctgatatcga ttttgagtgt gctcctgcta taaaagaatc tatcttaaaa agagcatcag
     6481 taggagatta tagttatact tttataggag atgacttcta tgatgctatt ataaattgga
     6541 ataaaagaag atttgatgta tatatagaaa aggattggat aaaattaact tttggtactg
     6601 tttcaaccct tcattatata gtccaagcat atactaaaga aggagagggt gtattgataa
     6661 atacacctgc ttatgaccct tttgcagagg ctgtagtaaa taataataga aagttgtgtt
     6721 gtagctcatt aaaattagat aacaatagat attatttaga tttagaggat atggaaaatc
     6781 aaatgaaata cgagaatata agattgctta tattctgtag tccacaaaat ccatcaggtc
     6841 gtatatggac aaaagaagaa ctatatcaag tgtcagagtt atgtttaaag tataatgtaa
     6901 ttttggtaag tgatgaaatt catagagata taatatttaa agattataga tttgtatctt
     6961 tgtggaatgc tcatccagaa atttataaaa atagtataat ctgtgtatct cctaataaag
     7021 gcttcaactt aggtggatta aaaacatcat atgtattaat aagagatgta aaaattaggg
     7081 agactttatt agaaaggcta aaaagtaatt caataacttc tccaaatgta tttgcaatac
     7141 cagcaatagt tgcagcatat aatgaaagcg aagaatggct agatgctatg actagttatg
     7201 tagaggagaa ttttgaaata gtttatgatt tctttgaaac taatatacca aaagctaaag
     7261 tgatgaagtc agactcttct tttttagcct ggatagatgt aagagaagta tttagaaatg
     7321 aagaagaatc taaagaattt tttagacatg caaacttaac tatggtagtt ggaagttatt
     7381 ttgtgaaaga tggagatgga tttattcgta ttaatgtggg gtgtcctaga gaaacattaa
     7441 atgaggctct aaatagaatc aaaaaaacgt atataagtat gtattgttaa atcataaaaa
     7501 aagtatctat ggtttatata aaaacacatt atttagttat caaatattac tggaattttg
     7561 tattccagta atattttttg attaaggaat attattgagg aatattaaat aatattattt
     7621 cataccctta tattaactta tataaaaata ttttattatt ttgggaacgg gttagctaac
     7681 ctttatctag tgtatattta tattgtaaga agcagtaaaa acttttcctt tactaagttt
     7741 attaataaac ttcttatctt tataaatttt gttagaattt atactatcag caagaccata
     7801 ccaaggttct atacataaaa aaggagcagt agaattagtt tcactataat aaggagtcca
     7861 aataccaact agagggaaat cttccataga tatagttaca tatttactac catcattatt
     7921 acatatagac acttcatcta tgttggtgta tatcaaagca tcattcttga atacttctgg
     7981 atttaactgt aagtttttta attttccaat aggtattata tcatctgtaa aagaaccatt
     8041 taaattgatt ttttctacat catttttact tttaaactca aggtagtgtt tagaaaaatc
     8101 attttgttcg taaaaaggaa ggttgaatgc aggatgtcca cctatagaaa agaatatatc
     8161 tttagaatca gtatttttta caatccattc tacctcaata ctattatcat ttaatgtata
     8221 gtttatgatt agctcaaaag aatatggata cttctttaaa gtagattcat tatctgttaa
     8281 tttataagtt acaaatgtat ctcctttatc tacaatctca aagtccatat ctctagcaaa
     8341 cccatgttga gtcatgctat ataaattttc ttctattatt gtttcattat caaaaagttt
     8401 acctactata gggaacaata taggtgattg tctaccccaa tattttttat taccatccca
     8461 aagaatgttt ttgtcgtatt ttttagaaaa tattttagtt agttcagcac caaaactgct
     8521 tgattcgata attaaatttt cattttgtaa tatattcatt taaaatctcc tttattatat
     8581 tttatgagta tattatacta taaagtataa agattattaa attttatttg atattatatt
     8641 tgaaaggtag attttagtat attttgaaaa ttttgttttg aaaatttggg attatttaag
     8701 aaattttgta ttataaatag aaggaaatag ataaattgta tagaataaaa tatattaaga
     8761 taagttaata atgttaaatg ggaagtgagt ttatggaaaa accaaataca aaagttgtta
     8821 actttcaaga gtataaagac agaaaaaacc aaagagaagt aaatagagac gaacttttaa
     8881 agcttataaa aaaaattgtg acttcaaaat agggagttgt taaactccct attttaatgg
     8941 gtttcataat aattaagaca ttctaagtcc atctatataa tctttgaatt gtgagaaatc
     9001 tgattcacta cttaattcta tggtttctga accttccgta taaaaattct taagatagat
     9061 agtataatta ttatcaacac aatcatgata aatacatcta tatccatctt catacaaact
     9121 ttttaactta gaaaaatcat ccacaatatc atctccttaa agttctttta aatatatttt
     9181 tacaaaaagc atctaattgt atgcaaattg acaatgtaaa ataaaggaaa tgaacataaa
     9241 atgtagaata atttttatat gtatgtaaaa ataaaaagaa aaagttgaaa tttttagaaa
     9301 ataagagtat tttttatcta aaaagagagt ttaaaaaata aaaaaatgtt gggaggataa
     9361 aaaatgagtt tattagaaag tatatcaaaa aacatatatt ccctagataa ctcttctatt
     9421 gaaaaaacaa agcagagatt ggataggctt atacatccaa ctggaagctt aggaaagata
     9481 gaagatattt gcatgcaatt agcaggaata tttggcaatg aaaattttga cacaagtaaa
     9541 aaggttataa ttgcttttgc gggagaccat ggtgtatatg aagaaggcgt agcacctgac
     9601 cctcaaaata taacaaaatt acagtttcca aatttttcga aaggtctatg cggagttgga
     9661 gtaataagta aatttgtagg ggcagatgtt gtagctgtag atgtaggaat aaactgtgat
     9721 gaaaaactgg atggggtatt agactacaag ataagaaaag ggacatcaaa tatggcaaaa
     9781 ggtccagcta tgagtaaaca agaagcaatt agatgtttag agataggtat tgaaatagca
     9841 gagcagtgta tagaaaaaga ttataaggtt attggtattg gggagatggg tatagcaaat
     9901 actactccaa gtacagcaat aatatctgta atttcagggt gtgacccgtt agaagttact
     9961 ggtataggtg caggtcttaa gaaagaaaga ctaaagcata aggctgaagt aattagaaag
    10021 gctattgaaa ttaataatcc aaatccaact gatggagtag atattttatc taaagtagga
    10081 gggtttgaaa taggctcaat ggcaggtgtt atattaggtt gtagtgctaa taggattcca
    10141 gtagtaattg atgggtttat ttcttatgca gcagcattaa ttgcatataa gataaatcca
    10201 aaaactagag aatatatgat agcatctcat ttatcagcag aatcaggaac taaaagagca
    10261 ttagacatat taaaattaga ccctctatta aatatggata tgagattagg tgagggaagt
    10321 ggagctgctt tagcatttga tataatagaa gcttcaaact atacttataa aaatatggca
    10381 acttttgatg aaattgacat gggaagataa atataaaaat ttaatatgta ggagtgtttt
    10441 gatgagtaaa attattctag taacaggagg agctaggtca gggaagagta actttgcaga
    10501 aaaactatgt tttgacagaa ataataatac agcttatata gcaacctcta ttccatttga
    10561 tgatgaaatg aaagatagag taaaaaaaca tcaagagaat agacctagaa actggaatac
    10621 ttatgaaata tatgaagata tatattccat aattaaggag atatataaag aacatgaaac
    10681 tgttatacta gattgtgtaa cattattagt aaataatcta atgtttgaac acaatctaaa
    10741 tatagaagaa tctagtcaag aagaaataaa caaattagaa caatacataa aagaacaagt
    10801 tgtcaaactt attgaagaaa tagaaaaaac aaatctatac tttgtatttg taacgaatga
    10861 gttaggtatg ggaattgttc ctgggaataa acttagtaga atttatgctg atattgtagg
    10921 tcgtataaat caatatatag cttcgaaaag taatgaagtt tattttgtag ttagtggcat
    10981 agctatgaag ataaaggagt agtatgcaat tatgaaaaga tttattttaa tactacagtt
    11041 tttgacaagg atacctataa aattaaatgt aggatttgat gatgaatttt ataagtcaat
    11101 agtatatttt ccacttgtag gttttgtcat aggtatatta tcctatttaa taggatggat
    11161 ttctatgctt ttatttgaac catttatagc ttctataata ataactctag ctggtgtctt
    11221 aattactgga ggacttcata tagatggatt aggagataca tttgatgcaa tatatagtta
    11281 tagggataaa gaaaagatgc ttgaaataat gaaagattca agattaggta caaattcact
    11341 tctagcaatt atgtttgtac ttttattaaa ggttggattc gtttacgata taataagtaa
    11401 taattcattg tgggttataa tttttatgcc aatgattgca aggttaggag taatgttatt
    11461 gacatataaa actgtgacac caagagaaaa aggaatggga aatttattta taggaaaatt
    11521 aactacaagt atgttaataa ctgctataat atacacatta ttgatagttg ctcttattac
    11581 taaatttata tttttattac ctaatatagt gttgattaaa gtattaggtt cgattatagt
    11641 ggtttttgta tttataatat tattcaaaaa acatatttat aaaaaaattg acggagtaac
    11701 aggagatata ttaggctgtg gaatagaact ttcagagctt gtatatttaa tttacatata
    11761 tttgttaatt tttatgtttt tttaaagtaa aaagtggtga taatatgata agattaatat
    11821 taataagaca tgcactgaca aatgataata aaaaaggaag attatcaggc catataaata
    11881 gttgtattag tgaagagggc aaactacaaa taaataaaat taccagatat ctgagtaatg
    11941 aaaacataga taaggtttat acaacaccat ctacacgtac taaagataca gtagaaaaaa
    12001 tatcaaaatt gaaattatta gaaatagaag aaaaagaagc tttaagagaa attagttttg
    12061 gagactttga aggaagaact tttgaagaaa ttaaaatcaa atatccaaat gagtttgaaa
    12121 aaatgataaa agaaggtaac aactatagat atccaaatgg agaaagtttg atagactctt
    12181 ataaaagagt ggcaaaagaa attgataata taattttaga aaataatagt aatttagata
    12241 caaagacaat acttatatgt tctcatgcag gaacaataag aaatataata acacatttga
    12301 tttctggtag ttataagtat cactggaact ttaaaattga taatgcatct attacagttt
    12361 tagaaattga tggtggattt gctgtaatag ataaaatgaa ttttacagac ttcatataat
    12421 ttaatcaaaa ccaaacatta caatctgtgt ttgtaatata tctgtaaaat tagcaatgaa
    12481 aatagaatat tagattaaaa ttaggttctt aattagatgt taaaagggaa aaaggttaga
    12541 tgcctttgca gcccccgcta ctgtgaaacc aacgaaacta taaataccac tgtcagtttg
    12601 atgggaaggt tatagaagta ggatgaagtt aagccaggat acctgcctaa tttaatttaa
    12661 aacaagaggt cttcggggtg aaagattttt aattaatata tataaaagtc ctatctttag
    12721 aagtattagg acttttttta atttgttttt tagtaaattt taacaaggag ggatggaaag
    12781 tggggaaaaa aataatgcta caaggaacag cttcaaatgt aggtaaaagt gtcttagtag
    12841 caggtttgtg tagaatattt aagcaagatg gttatactgt tgctcctttt aagtcacaaa
    12901 atatggcttt aaattctttt ataactaaag aaggattaga aatgggaaga gcacaagtat
    12961 ttcaagcaga ggctgcgaaa atagagccaa tagctgatat gaatccagtt ttattaaaac
    13021 cttctggaaa taataaaagt caagttattg taagaggtaa agttgtagga gaaatgcctt
    13081 cttctaagta tcatgattat aaattggagt tagtagatgt gttgaaggaa acatttaata
    13141 gcttaaattc aaggtatgat attgtagtta tggaaggggc aggaagtaat gcagagataa
    13201 acttaaaaga tagagatatc tctaatatgg gtatggcaga aatagctgat gcacctgtaa
    13261 taatagtcgg agatattgat agaggaggcg tatttgcctc attagcagga acaatgcttt
    13321 tattaaatga agatgagaaa agaagagtaa aaggtgtaat aatcaataaa ttcagaggaa
    13381 aaaaagagct tttacaagat ggtgtaaaga tgctagaaga catcataaaa gtacctgtta
    13441 taggagtagt accttataca gatataaaaa tagaagatga agacagtgta actacgagat
    13501 ttaagaaaaa aatgaataaa agtgatatac acatagaaat aattagaacc ccacatatgt
    13561 caaattttac agattttaat atatttgaga cacaagaaga tgtaagtata agatatgtag
    13621 actatggaga atctttagga aatccagata tattaataat acctggaact aaaagtacta
    13681 tagacgattt aacatatata agaaaaagtg gtcttgaatc gcaaatcaaa aatttacata
    13741 gtcaaggtaa attgatattt gggatatgtg gtggatacca aatgttaggt aaaaaattaa
    13801 aagaccctta tcatgttgaa agtgaaattg aagaagttga tggaataggt cttttagata
    13861 cagaaacaac gtttgagaaa gaaaagacta caacacaagt agaagctact attgttgaat
    13921 gtatcagtga atacatgaat aaccttaagg gaaaaaaagt aaaaggttat gaaattcata
    13981 tgggaattac aaagcgaggt aatgatgtaa gaagtttaga tttaataact aaaaaacttg
    14041 ataaagaagt gaattatact gagggaagtg taaataaaga ggggaatgta attgggactt
    14101 atcttcatgg aatatttgat gaaataagct ttacaagagc aattttaaac aatataagaa
    14161 agaaaaaagg tttaggagaa ttagaaagca aagtaaactc ttttaatgaa tttaaggata
    14221 aagagtatga taagttggct gattttttaa gagaacattt agatatagag aaaatatatg
    14281 agattatgaa ataatgatga cctttattta taatttaggt aggaggtgta ttatgaaaaa
    14341 aattttaatt gcgggtacta atagtggagt aggtaaaaca acaatatcat taggaataat
    14401 gcaagctttg gttaagagaa atatgaaagt acagccatat aaagtagggc cagactatat
    14461 agacccttca tatcacactt ttataactgg aagacattct agaaatttag attcttatat
    14521 gttagatgat gaaaaaataa agtatatagt aaataagtcc tcaaaagatg cagatatttc
    14581 agtaatagaa ggtgttatgg gcttatatga tggctttgga atagatttag ataattgtac
    14641 aagttcacat acttcaaagg tattaaagtc acctgttata ttagttataa atggtaaatc
    14701 tatggcagca tctagtgctg ctatggtact tggatataag gaactagata aagatgtaaa
    14761 tataaagggt gttatagtaa ataatgtaaa gactaatagc cattatcaaa taattaagag
    14821 ttctatagaa aaatattgta atgttgaagt attggggtat tttcctccaa ataacaaatt
    14881 ctctttggaa tctcgacatc taggattagt tcctagtgta gaaatgaaat cactaaggga
    14941 aaaattttat accttagcag atgaaattga acactatata gatattgaca gaataattga
    15001 aatatcagaa agtgatgaat ttgagagtga ttttgatttt caaactttga tagaaaataa
    15061 taaaataaaa gaacatgtta ataataaatc aatagctata gcatatgata aagcattcaa
    15121 tttttattat agagaaaata tagagctttt agaggaactt ggtttagaaa taaactattt
    15181 tagccctctt gaagatgtat cagtgccaaa tgcagattat atttatattg gaggaggttt
    15241 tccagaaata tttggaaaag aattagaagc aaatgagtca atgagaactt ccatattaga
    15301 agcacataac aataatatac ctatttatgc agaatgtgga ggactgatgt acctaggtga
    15361 gaaactattg aatcaagaag aacaagaatt taatatggtt ggaatattta gtggaattag
    15421 taagatgaca tcttctttaa agagatttgg gtactgtatt ggtgtagcca aggaaaatac
    15481 tcttttatct aaaaaagggg aatccattaa agggcatgag tttcatcatt caatatttga
    15541 aagtgatgaa aaatgtgtat attcaatgag aaaagaaaga gatggaaata tagtagaaga
    15601 gtgggatggt ggttatagta aaggaaacac tttggctaca tatcttcata ctcattttta
    15661 taataactta aattgtatag aaaatttttt gaaaaaagga aatgaataaa tgagtatttt
    15721 atctatttat ataggatatg tgacagactt aattgtagga gacccatatt cttttcctca
    15781 tccagtgaga tttattggta aacttataaa ttttactcaa ggtataataa gaaaggtctc
    15841 taaaaatgat aggcagttaa aatttggggg atttatatta tggtttataa ccgttggaat
    15901 aacatattta acaacttatg ctatagtgaa gttatttagt tttaatatat tattgagtat
    15961 tgtagtgaat agttttataa tttatacaac actagccaca aaatgtttaa aagacgaagc
    16021 attaaaaatt tataatgtat taaaaactga agatatagaa aaatctagga ttcagctatc
    16081 ttatatagta ggtagggata ctactaattt aagtgaacct gaaataataa gagcaactgt
    16141 agaaactgtt gcagaaaata ctgtagatgg tataattgcg cctatgtttt atgcatttat
    16201 tggaggagca ccacttgcta tggcctataa agctatcaat acattggact caacagttgg
    16261 atataaaaat aaaaagtata aagatattgg ttttgcatct gctaagattg atgatatagc
    16321 caattatata ccagctagaa tatctgtcat tcttatgaca attggaagtt tctttttaaa
    16381 ttataactat aggaactgtt ttaaaatctc tattagagat agaaagaatc ataaaagtcc
    16441 aaattgtgct ttttcagaag gtgcagtatc tggtgctcta ggaatacaac taggaggtac
    16501 caacgtttat tttggggaaa aagtatataa gccaacaata ggggataagc ttagggagat
    16561 agataaagaa gatataatta aaactaataa aattatgtat gcatcttcat ttgtatctat
    16621 gttggtattt acactaatat atgtgttatg taggatgatt ttaattaact taattatata
    16681 aattattgtt tgttaactta agggggacat agatgaagga tttagggcat ggtgccaatg
    16741 tagatgaaat ggcaagatta tatgggaaaa acccaaaaga aataattgat tttagttcaa
    16801 acataaatcc aaatgtatta ccaaatttag agagatacat tttaaaagga ttagaagagt
    16861 gtaggaatta tccagatata aattatacaa acttgagaga aaatatatca aaatatatag
    16921 atataaatcc agactttata atacctggca atggtgcaac agaagtgatt tatttgctta
    16981 tgaagagtat taaaaaaaaa ttggctataa taaatccgac tttttcagag tatagaagaa
    17041 gtgctgagtt aaataattta gatattatag atttagagtt agatttagaa aataacttta
    17101 aacttaatat agatataata aaagaaaata taaaaagatt tgatagttta tttatatgta
    17161 atcctaataa tccgagtggt aatgtccaag atttaaagga acttgttcat ttactagata
    17221 aacataataa ggtactaata attgatgaaa ctttcatgga atttgttgaa gatgaaagta
    17281 aatatagttt ggttaaatat atagaatcaa ataaaaatat atttataatt aaagctgtga
    17341 ctaagttttt tggtatgcct ggtttaaggc taggatatgg tcttacaagc aacactgaaa
    17401 ttatgaacaa aatttatgaa cacaaagagc catggactat caattctttt gcagatatac
    17461 tatccaattt tatttttgaa gataaagagt atattaaaaa tagtaaagaa tattacatag
    17521 aagaaagaaa atatatgtta caagagttga gaaacataag aaatataaag gtctatgata
    17581 cagatgctaa ttttatcttg ataagaatat ataaaaaaac aactaaagaa ttgaaaaaag
    17641 atttgtttaa gcaaggaaac atattagtta gagatgcatc taattttata ggattagatg
    17701 atagctttat aagagtggct ataaaatctc atgaagataa caaaattctt atagaaaata
    17761 tgaaaaattt attgggtgat taaaatgaaa tcttatggaa tatgcccagc atcttgtgga
    17821 gaatttgtac aaggtataat tgatgatgaa gaatatttat gttcatatgc aatagatatg
    17881 tattctaaag tgtatattga agaaaaatta gtagatataa atttagggag atataagtca
    17941 aggttagcaa ttgaaaaggt atttgaaaaa tttaatctac ctaaaaaata tactaaaaat
    18001 atttctttaa atataaatag taaaatacct gttggaaaag gaatggcaag ttcaactgct
    18061 gatataggag ctactataaa ggcaacatta tcattgatag ataaagattt aagtagcgag
    18121 gagatttcta aattagcagc agaaatagaa ccaacagatt ctatatttat agataaaaat
    18181 agtatattta atcctctaaa tggaactgtt ataaaatacc taggaaatct gaccaatgcg
    18241 aaagttgtaa tacttgaacc aaacaaagta ctagatacta tgaaaattag attgaggcaa
    18301 gattataata aattaaaagt agagaataaa gaagtaataa aaaaatcatt tgctctttta
    18361 gaagaaggat tgaaaaaaaa taatttatct ctagttggag aggcttgtac tttgagtagc
    18421 ttagcaaatg agaatataga aaaaaaagag tatttaaatg aaataataaa aatatcaaaa
    18481 aaatatggag catatggagt aaatattgct cacagtggaa ctgtagtagg tattttaatt
    18541 gataagttta tgaatgataa aaagatgata gatgccttat gtgaatctaa cataaattct
    18601 gtctataata aaatttatac acaaaacata attaatggag gaattaaggg ggaaatagaa
    18661 tggaatacat aaagaatcct atgaaaatag aagaaaaaag ttttgaattg atacaagaaa
    18721 taatagacga aattagacca gattataaat ttaagaataa tatcgaagaa aaaataataa
    18781 aaagagctat acatactact gctgattttg attacttaga tatattaaaa atatcagaag
    18841 aagcagttga tagtataata gatgcattaa aaaataatgc aagtatttat actgatacaa
    18901 atatggctct tagtggtata aataaaagaa agttagaatc attaggatgt aagtataaat
    18961 gtttagtggc agatgatgaa actgtaaaat tagctaaaga aaaaggaatt actcgttcta
    19021 tggcagcagt agaaattgca gctaaagaag aaggaagaaa aatattcgtt ttaggtaatg
    19081 ctccaacagc tttatataaa gttatggaga tgaaatcaga aggtagatta gatttagatg
    19141 cagttatagg agttcctgta ggttttgtag gagcacaaga atcaaaagat gaagttgaaa
    19201 aaacagatat accatatata atttctaaag gtagaaaagg tggcagtaat ttagcagcag
    19261 caatagtaaa tgctatatta tatactatgt aggtacctat atggaagaat atgtatatat
    19321 agatggaaaa aaatatagaa gaggatatac tacaggttca tgtgcaacag gtgcatctaa
    19381 ggctgctgta tatatgttga ttacaaaaaa tagaatcaat actataaata tagatactcc
    19441 taaggggata ccattactac taaaagttga taatataaat atttctgata catttgtgga
    19501 atgttccata aaaaaagatg gtggagatga tatagatgca actcatacca tggatattta
    19561 tgcaagagct gaaattgtag ctaaaaatga taagaacaaa gggtatctta ctctaaagga
    19621 tatagataat ttaagcacca atagtgagtg taaaagtgag ctctataagt ttattagggt
    19681 ttatggcgga actggtattg gtgtggttac aaaaaaaggt cttagcgtgg atgttggtaa
    19741 acctgctata aatccgactc cacttaaaat gataaatcat gaaataagaa agcttatagg
    19801 agataatttt gaatctatac ttggaaatga taaagtttta aaaataacaa tctttgctcc
    19861 acaaggagaa actgtagcaa aaaaaacatt taatccaaga ttaggtatag ttggaggaat
    19921 atctataata ggtacaactg ggattgttga acctatgagt gatgagggtt ggaagaagtc
    19981 tctatctata gaacttcaga tgaaaaaaga acaaggctta gataaaataa tattggttcc
    20041 aggaaatcat ggagaacagt ttataagaga aaaattaaac ttagatatta agtatgtagt
    20101 tagggtaagt aattttatag gctatatgat taaagaagct caaagaatag gatataagaa
    20161 aatcttaatg gcaggtcata taggtaaatt tataaaagta tctgctggta tttttaatac
    20221 tcatagtaag gtagcagatg ctagaagtga gatattagtg gcaaacttag ctttaatggg
    20281 agctagatac gaatttttaa ataaaataaa tcaatgcgta actactgaag aagctgtaga
    20341 gctaataaat aatagtgaat atagagaagt atataatata ttaagtaata aatgtaggga
    20401 gagagtaaag caatacttga atgaagattc agatgatatt gatgtggaag taatcatatt
    20461 ttcaatggat aagtctttat taggtaaatc ggataataca gatgatttag tggaggtctt
    20521 tatatgataa acataatagg tctaggacct ggtaacttag actatataac aaaaaaaggt
    20581 gaaaatttaa tttccacttc tgatgtatta attggtggta aaagaaattt agagtctata
    20641 aaaaattttg aaggagaaaa aatagttctg gattctaatt taagagaaat tatagagtac
    20701 ataaataaca ataaagaaaa gcaaatatca ataatagcat ctggggaccc actaatatat
    20761 gggataggta gatatctatc taaaaatatt gataataaga tgttaaacat ggtttctggg
    20821 attagttcat tacagtacat attttcaaaa atatatgtag atatgaatga tgtatatatt
    20881 acaagtagtc atggtaaagt accagatttt gattacatat tatcacataa aaaagtatgt
    20941 atggttacag attcaaagat aggaccaaaa caaataagta gagaaataat agatagaaat
    21001 ctaaataaaa ttattgttgt aggagaaaat ctgtcatatg acaatgaaaa aataacaata
    21061 gcaaaaccag aagagataat aagaatggac aattttgata tgaatgttgt ggtgatttta
    21121 gatgaggaat agtgaattta taacaggtaa agttccaatt actaaggaag aggttagagc
    21181 aatatcaata agtaagttaa atttagtaaa tgctaaaaac ctcatagaca taggggctgg
    21241 tacaggaagt gtaagtgttg aagctgcata taattatcct aatttaaagg ttatatctat
    21301 agagaaaaat gatgatgcta tagagcttat agagaaaaat aaaaaaaaat tcaacttgaa
    21361 aaatatagaa gtgataaaag gatatgctcc aattaatcta gggttaaatg ttaaagttga
    21421 gtctattttt cttgggggaa caggaaataa tctggaagaa ataatagaat ggtctaaaaa
    21481 aaatctcgtt acaggaggaa gacttgtagc taattttata ataatagata catttaatca
    21541 aactttaaaa ctgcttaaaa agcatggatt taaagaaata gatgtatgtg ttttgaatgt
    21601 ttctaaacta gagaaactag gaaaaggtga atattttaaa ccactaaatc ctatatatat
    21661 aatatcttgt gaaaaagggg aaaatgatga tgaataaagt acattttgta ggagcaggac
    21721 ctggagataa agagctgata acattaaaag gatacaaatt attaagtaat gcagatgtag
    21781 tgatatatgc aggttcactt gttaatcctg aacttttgga atactgtaaa gaagattgcc
    21841 aaatacataa tagtgcacat atggatttac aagagataat agatgttatg agagaaggta
    21901 tagaaaataa taaatctgtt gtaagactgc aaacaggtga tttttctata tatggttcaa
    21961 ttagagaaca agtggaagat ttaaataaat tgaatataga ttatgactgt actcctggag
    22021 taagttcttt tttaggggca gcatcatctt taggggttga atatacagtt ccagaaattt
    22081 ctcaaagtgt aattataaca agaatggaag gcagaactcc ggttccagag aaagaatcaa
    22141 tacaatcata tgctaagcat cagacatcta tggtaatatt tttatctgtt caagaaattg
    22201 agaaagttgt gtctaaatta ctggaaggtg gatatccaaa agatactcct atagcagtta
    22261 tatacaaagc aacttgggca gatgaaaaaa tagttaaagg aactttaagt gatatagctg
    22321 taaaagttaa agaaaacaac ataaataaga ctgctttaat aatggttggg agatttttag
    22381 gagaagagta taataattca aagttatatg ataaggattt caaacatgaa tatagagggt
    22441 aatattgcta taatctgtat tacagaaaat ggaaaaaaat tagctctaaa gataaattct
    22501 ctagtaaata actgtgttat atatcaagta aaaaataaaa aaagtaattt agttgttgaa
    22561 gaaacatgtg tgcatacagt tcaaaagaag ttaagtgatt ttgtaggaga aatatttagc
    22621 aaatttgatt acatagtatt tataatggct acaggtatag ttgtacgaag tatagcacca
    22681 tacataataa gtaagtttag tgaccctgca attttggtaa tggatgaaaa aggcaaaaac
    22741 gtaataagtt tattgagtgg tcatattgga ggggcaaaca gcttgacaca gtacataagt
    22801 agtcttattg atgctaatcc agtaataaca acagctactg atataaatca aaaagcttcc
    22861 ttagatatga tagcaaaaaa actaaatgca catattgata attttagaga aagtgtaaaa
    22921 gaagtaaatt ctatgctagt gaataataaa tgtgttggat tatatgttga tgaaggatat
    22981 caagttgata ctaggggatt taaacttata gaaagtaagg atgagttaag agatagtttt
    23041 tcaaacacat atatagaaaa attagttgta gtaagcaata aaataaattg tattgaagat
    23101 attgagaatt taaacctaga taataaattt gaacattgct atagtaccca aaaaataata
    23161 aaggtaattc caagagatat agtgatagga attggctgta gaagaaacac agatagtgaa
    23221 ctgatgtata attcacttga agagtttctt aataaacaaa atatagatat tagagcaata
    23281 aacacagttg gaagtataga actgaaaaaa gacgaaaaag caataattga attatcaaaa
    23341 atattgaagg tgccatttaa aacattttca gtagatgaaa tatctaaggt tgataatctt
    23401 tttgataaat ctgattttgt taaaaaaaat gtgggtgtgt attcagtagc agaacctgta
    23461 gcatatcttt tgagcaaagg taatttgtta gttgaaaaac ataaatataa aggaataact
    23521 ttttcagtgg ggagaataaa aatatgatat acgttgtagg aattggacca ggaagtaaag
    23581 atacaatgac tttagaagca ataaaagcaa tagaagattc tgaggctatt gttggatata
    23641 agacttatat aaaactaata gaagaattta tacaaggtaa agaaataatc caaaatggta
    23701 tgaggcaaga agttgataga tgtaaacaag cagtggagga agcaaaaaaa ggaaaaaaag
    23761 tagcagttgt aagcagtggt gatgctggaa tatatgggat ggcaggtctt attttagaat
    23821 taatatctaa agaagatgaa gatataaaag taaaggtaat tccaggcgtt actgcaagta
    23881 ttggtgcagc agctatactt ggagctccta ttatgcatga tttctgtcat ataagtttga
    23941 gtgatttaat gactccgtgg gaagtaattg aaaaaagatt gagattggct gctgaagccg
    24001 attttgtaat ttgtttgtat aatccaagaa gtaagggaag aagtgaacat ctaagcaaag
    24061 cattcaaaat aatgggtgag tttaaaggtg gagatacacc tgttggagtg gtaaaagatg
    24121 taggtagaga aaaagaagaa aagtttgtat gtacttttga aaatatggac tttgaaaaag
    24181 tcgatatgac tacaatggtt ataataggaa ataagtctac ctatattaat ggtgaattga
    24241 tgataactcc aagaggttat acagtatgat tttaatttta ggaggaactt cagatagttt
    24301 atctatatgt gataagataa atgaactgaa aaatcaacca tatatccttt cagttactac
    24361 agattatgga agggaacttg cacaacaaca tgcagagaat gtaattttag gtaagcttgg
    24421 aaaagaagat atgctaaaat ttataaaaga taataatata gtaaaaataa tagatgccac
    24481 tcatccttat gcagttgaag tatccaaaac tgctattact tgtgcaaaac tattgaatat
    24541 agattatata aggtttgaga gaaaatcttt aattgaagaa atagattatg ataataaatt
    24601 tatagtagat acaattgaag aagcctgtga aatagcaaat aaaataggga caaatatatt
    24661 cataggaaca ggaagtaaaa atttgaacag atttatagag gaaataagtg ataaaaattt
    24721 agttgttaga gttcttccaa cgagtgaagt catattaagt tgtgaaaaat taggtttaag
    24781 tgcagataat atagtagcta tgaaaggtcc atttagccag tatataaatg aagaaacata
    24841 taaacattac aatatagatt tagtcataac aaaagaaagt ggaatagctg gtgggttctt
    24901 agagaaggta aatgcatgta aaactttcaa tataccagta ataattataa aaagagaatc
    24961 gattaactac gaaaatgtat ttaatgacat aaataaaatt aaagacatac ttgtgtaatt
    25021 tttaggagga gaatatatga agaaagcctt attagtagtg agttttggta caagctatca
    25081 tgaaacgaga gaaaagacaa tagatatatg tgaagataaa ataaaaaatt cgttaaaaag
    25141 ccatgatttt tttagagctt atacatcaaa tatgataata aataaaataa aaaaaaggga
    25201 tggaatagaa atagataatc caatacaggc tttagataaa atatatgaac aaggatatga
    25261 tgaagtaata atccaaacac ttcatattat atgtggcgaa gaatttaaca aattaaaaga
    25321 acaagtagat ggatattctt ctaaattcaa aaagattgta ttaggaagac ctttgcttac
    25381 acatattgaa gattatcagg aagctgtaga ggcaattaag catcaaattc ctcatatgga
    25441 aagtaatgaa gcagtagtat ttatgggaca tggaacactt catgaatcac attcagcgta
    25501 tccagcattg gaatacatgc ttagggataa tggaataaat gcttatgttg gtacagttga
    25561 agggtatcca gaaatagaac atgtaataag aagattaaaa gaaggaaata taaaaactgt
    25621 aaatttgatg ccatttatgt tagttgcagg agaccatgct ataaatgata tggcaggaga
    25681 tgaagaagat tcttggaaaa caatattaga agaaaatgga tttaacgtaa gagttcattt
    25741 aaaaggacta ggagaaaatt cttatataca agataaattt gttcgtcatg ctgtaaaatg
    25801 tgcagagaat gcgaagttct atggtatagg agcagggcca ggagatggtt ctttacttac
    25861 gataaaagcg gttaatactt taaagaaact ggatattcta tacactccag aatcaaaaaa
    25921 gggtggagat agtctagctt tatcaatagt tagtgaatat ttacctgaat cagtggaaat
    25981 aaagtctagg catttcccaa tgagttttga tgggaatgaa aaaagtttag cttgggacaa
    26041 tgtggcacaa gaaattatat cagatgttaa tgatggtaaa aatgtaggat ttgttacatt
    26101 aggagaccct atgatttata gtacatatgt atatataatg aaaagaatat taggagaggt
    26161 agaagtcgaa actataccag gaatttcatc attttccaat atagcatcta atcagaattt
    26221 tccattagtc atggataaag aagctttagt ggtaattcct tgtactatgg aagatgataa
    26281 gatagagtat gctttgcaaa attataattc aatagtattg atgaaagtat ataaaaattt
    26341 taaagaaata ataaaaaaat tagaaaagta tgatttaata gaacatgcta ttttagtaag
    26401 taattcttcc caagaaagcg aaaatgtgtt tacagattta aaagaagcgc accttgaaga
    26461 taagatatct tatttttcta ctatactagt aaataaagat aataaaataa aataggtgaa
    26521 agcaatattt aaaggagact taatatgaat atagtggttg gaactagggg tagtaatcta
    26581 gcgcttatac aaacagaatg ggtaataaat gaattaaaaa agaagtatcc agaaattagt
    26641 tttgagatta aaatcataaa gacaaaagga gatttaattc aaaatgtttc actggataaa
    26701 ataggtgata aaggattgtt tgtcaaagaa atagagcaac aattattaga tggaaaaata
    26761 gacatagcag tacatagtat gaaagatatg ccttcttatt tagcagatgg actaaaattt
    26821 gctcatacgc ctaagagaga agacccaaga gatgttctaa tacttagaga aggatataaa
    26881 aatttagatg atttgcctca tggagcagta ataggaacag gaagtaaaag aaggaagttt
    26941 caattattga aacaaagacc tgatttaaat atagtacaag ttagaggtaa tgtggaaact
    27001 aggatacgaa aaataaaaga tgaaaacatg catggtattg tgttggcagc atcaggaata
    27061 attagagcta atttacaaga taaaataagt tcttatttac ctgttgatgt tgttattcca
    27121 gcacctgccc aaggagcttt agctatagaa attagaagca atgatagtac gatagaggga
    27181 atagtaaatt cactgaagga tgagaataca gaaatccaaa tattggctga aagaggtttt
    27241 ttagatggtg taaatggaag ttgtcatatt ccaatggcag cttattgtga aataatccaa
    27301 gataaaatac atcttactgg cttatatgga gattcagaag gaaaaaaagt agtaatcaag
    27361 tctatagatg gagatatttc ttctcctaga gagttaggtt taaagttagc taaacttgta
    27421 ttgaaggagt atgagaatta tgaagggtaa ggtttactta gtaggggcag gaccaggtga
    27481 ttataaactc atgactttaa aaggtttaga gtgtataaga aaatcggatg taatagtata
    27541 tgatagatta gcaaatagta gttatttaag agaagctaag cctgattgtg aacttatata
    27601 tgtaggcaag gcatcaagta atcatatttt gccacaagaa gatataaata gaattatagc
    27661 agaaaaagct aaagaaggaa aaattgtaac tcgtcttaaa ggaggagacc cttatgtatt
    27721 tggcagaggg ggagaagaag cagagacttt agtagatgaa ggtatagaat ttgaagtagt
    27781 tccaggtata acttctgcta taggaggttt atgttatgcg ggtattccta taacacatag
    27841 agaccatgct tcgtcatttc atgtaataac aggtcatttg aagggtgatg atagtggaga
    27901 attaaactgg aatgctcttg caaataacaa aggtactctt gtgtttttga tgggaatttc
    27961 aaacctagag aaaataagtg aaaacttaat gaaagaagga aaagataagg atacacctgt
    28021 tgctcttata agttgggcaa ctagatataa tcaaagagtt gttacatcta cacttgaaaa
    28081 tgtttatgaa actgctatta aagaagaagt aaaaccgcca actcttatag tagttgggag
    28141 tgttgtagga cttagagaaa agttgaactt ctttgaaagt aagcctttat ttggaaaaag
    28201 tattgctgta actaggtcta gaaatcaaaa tagtgtattg gtagaaaaaa taatggattt
    28261 aggtggaaat cctatagaaa tacctactat taaggtagaa aaaatacaaa ataatattaa
    28321 cttagaaaat gaaataaaaa atataaataa gtataattat ctaatactaa ctagtaaaaa
    28381 tgccgtagaa atcttctttg aaaagatata tgaaatgaat tttgatttaa ggatattatc
    28441 taatttaaag gtatgtgcta taggttctgc tacatcaaat gagttgaaaa aaagaggaat
    28501 tatagcggat atagtaccaa aaaaatttgt agcagagtca ctgtatgaag agttagcgcc
    28561 tattttaaat gatgacgata atatacttat acctagagca gaaaatgcta gagattatct
    28621 ggttgacaaa ctcaaggcta tttgtgaagt aacagaagta catatatata gaacagtaat
    28681 agatgaggag aaaaaaggtg agatattaga tattttaaat tctaatgaca tagattatat
    28741 aacatttact agttcctcaa cagtaaataa tcttgttgaa attataggaa aagaaaatat
    28801 taaaatatta gaaaaaataa aaacactatc tataggtcct ataactacag agacaataaa
    28861 tagtttggga ataaaattgt acaaagaatc tgctacatct actatagatt cgttagtaga
    28921 tttaattata aaaaattaat tttggaggct tgaatatgtt aagaagacca agaagactaa
    28981 gagcaagtaa agcaatcaga aatttggtaa gagaaactaa ggtgaatgta gaagacttaa
    29041 tatatccact gtttgtagta gagggggaaa atataaaaga agaaattaaa tctttaccag
    29101 atgtctatca tttatcaata gatatgctag aagacgaaat aaaagaaata agtgagttgg
    29161 gaattgaaca tataatgtta tttggtgttc cagatgaaaa agatgagtgt gcttcacaag
    29221 cttttaatga taatggaata gttcaaaagg caattagaaa ggtaaaagaa ataaattcag
    29281 atataaatgt aataacagat gtctgtatgt gccaatatac aagtcatgga cattgtggga
    29341 ttttaactga tactggttat gttgataatg ataaatcatt ggagtatttg gctaaaatat
    29401 ctgtaagcca tgctaaagca ggagctgata tggttgctcc atctgatatg atggatggaa
    29461 gaatacaagc aataagagaa gctttagatg aaaatggatt agaaaatgtt ggaatcatgg
    29521 cttatagtgt taagtatgct tcaaattatt atggaccttt tagagaggca gctcattcag
    29581 caccatcttt tggagataga aaaacatatc aaatggaccc agcaaatagc aatgaagcta
    29641 taatagagac tgaacttgat atattggaag gtgcagatat acttatggtt aaacctgcat
    29701 tatcatattt agatattata agaagagtta aagataattt tgacttacct ctagcagctt
    29761 ataatgtaag tggagaatac tctatgctta agtttgctgt gaaggaaggt ttattaaatg
    29821 aagatgtaat tcttgaatca attacatcta taaaaagagc aggagcagat ataataataa
    29881 cttattttgc taaagacatt gctaaactgt tgaaaaaata aattctagca gtataaagaa
    29941 tatcaaaaag tataggaatt gtaattaact attatacagt agttttgttt agacatttat
    30001 tgaagaataa tagaaactaa tttgcaattt ctatacttta tttatgtaac taaataaaat
    30061 ttggaggtag aagatgctat atcctattaa tttaaaatta gatgagttag atgtagttat
    30121 aattggtggt ggagaagttg catataggaa atgtaaaaat tttttagagt ttaacaaaaa
    30181 tgttactata gtttctaaac aaattttaaa taaattttat gatttaaaag gaaatataaa
    30241 aataataaaa gatgattata aagaaatata tataaaagat gcttctgtaa taattgctgc
    30301 cacaaataat agagagttaa atatggaaat aggattatat tgtaaagcaa aaaataagct
    30361 agtgaatgta gttgataata tagaaatatc gaactttact gttccatcat atataaaaag
    30421 aggagattta cttataagtg tgtctactgg gggcaagagt ccttcattat catcaaagat
    30481 aaaaaaagaa attgaagaga gatatactga agattatgag gagtatttaa atgtattagg
    30541 agatataaga aaaaaggtta taaaaaaata cgaagataaa agtaaaagaa aagatgtgct
    30601 taatatgttg gtaacacttg acctagaaga acttaagaag tttgatatat aaaaaataaa
    30661 ataaaaaatg ttaaaaaggt gttgacggat
//
LOCUS       DAMJWC010000048        29367 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMJWC010000048 DAMJWC010000000
VERSION     DAMJWC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29367
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.048"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(146..1015)
                     /locus_tag="PC503_002503"
     CDS             complement(146..1015)
                     /locus_tag="PC503_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2528469.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1112..1969)
                     /locus_tag="PC503_002504"
     CDS             complement(1112..1969)
                     /locus_tag="PC503_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2528470.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(2184..4202)
                     /locus_tag="PC503_002505"
     CDS             complement(2184..4202)
                     /locus_tag="PC503_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2528471.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(4473..5249)
                     /locus_tag="PC503_002506"
     CDS             complement(4473..5249)
                     /locus_tag="PC503_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2528472.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLIDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(5306..6277)
                     /gene="asrC"
                     /locus_tag="PC503_002507"
     CDS             complement(5306..6277)
                     /gene="asrC"
                     /locus_tag="PC503_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF2528473.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(6290..7081)
                     /gene="asrB"
                     /locus_tag="PC503_002508"
     CDS             complement(6290..7081)
                     /gene="asrB"
                     /locus_tag="PC503_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF2528474.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(7082..8089)
                     /gene="asrA"
                     /locus_tag="PC503_002509"
     CDS             complement(7082..8089)
                     /gene="asrA"
                     /locus_tag="PC503_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF2528475.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            complement(8480..9169)
                     /locus_tag="PC503_002510"
     CDS             complement(8480..9169)
                     /locus_tag="PC503_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2528476.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(9232..10080)
                     /locus_tag="PC503_002511"
     CDS             complement(9232..10080)
                     /locus_tag="PC503_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2528477.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(10099..10986)
                     /locus_tag="PC503_002512"
     CDS             complement(10099..10986)
                     /locus_tag="PC503_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2528478.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGKDATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(11044..11847)
                     /locus_tag="PC503_002513"
     CDS             complement(11044..11847)
                     /locus_tag="PC503_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528479.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(12007..12459)
                     /locus_tag="PC503_002514"
     CDS             complement(12007..12459)
                     /locus_tag="PC503_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF2528480.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(12589..14091)
                     /locus_tag="PC503_002515"
     CDS             complement(12589..14091)
                     /locus_tag="PC503_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2528481.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(14124..14990)
                     /locus_tag="PC503_002516"
     CDS             complement(14124..14990)
                     /locus_tag="PC503_002516"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF2528482.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(15075..15746)
                     /locus_tag="PC503_002517"
     CDS             complement(15075..15746)
                     /locus_tag="PC503_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF2528483.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(16019..16510)
                     /locus_tag="PC503_002518"
     CDS             complement(16019..16510)
                     /locus_tag="PC503_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2528484.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(16532..17896)
                     /locus_tag="PC503_002519"
     CDS             complement(16532..17896)
                     /locus_tag="PC503_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2528485.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            18315..19490
                     /locus_tag="PC503_002520"
     CDS             18315..19490
                     /locus_tag="PC503_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2528486.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(19663..21060)
                     /gene="asnS"
                     /locus_tag="PC503_002521"
     CDS             complement(19663..21060)
                     /gene="asnS"
                     /locus_tag="PC503_002521"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF2528487.1"
                     /translation="MQKEFITVKELYREKEHYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(21137..21370)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(21539..21733)
                     /locus_tag="PC503_002522"
     CDS             complement(21539..21733)
                     /locus_tag="PC503_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF2528488.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(22006..23679)
                     /locus_tag="PC503_002523"
     CDS             complement(22006..23679)
                     /locus_tag="PC503_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2528489.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(23689..27087)
                     /locus_tag="PC503_002524"
     CDS             complement(23689..27087)
                     /locus_tag="PC503_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2528490.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(27254..28450)
                     /locus_tag="PC503_002525"
     CDS             complement(27254..28450)
                     /locus_tag="PC503_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2528491.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSISYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(28471..29292)
                     /locus_tag="PC503_002526"
     CDS             complement(28471..29292)
                     /locus_tag="PC503_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF2528492.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
BASE COUNT         9472 a         5267 c         2985 g        11643 t
ORIGIN      
        1 tgatatatta tatatgaata taccattttg ttttttaata aaaaatcatg ctacatcaat
       61 agtaagcaac tattaatgta gcatgatttt ttgtatctaa ataatcttag tatttaccta
      121 tcagtataga ttgatatatc aaaaactata gtcttctata ttcttctctt tttagctttt
      181 ggttacttag atagtaatca atttcatcaa ttagacgttg tttatcatca ggtaatacac
      241 cttttaaatt agcataattt gatgcatgat tacttctaaa tacaattttt tcattagcat
      301 ctatattctt tatcatctct ttaatttctt gtaacacagc cttatcctct agtattgtaa
      361 actctcctgc cttaagtaaa tcgtaaagtt cagtattagg ttctaccatt aaactaagta
      421 cacccacata atctggtgaa attgctccta gcatttttcc tgtatcaact gcatgctgat
      481 gtgttttttt agttcctcca agacctgcta ttacagtggc tgataattta atcccacttt
      541 ttttaacttt tctaccaact tttattaatt gttcactact aaaacctttc ttaatatctt
      601 ctaatacttc attgcttcca ctttcaagcc ctagataaat cattttaaca ccaagttttc
      661 ttaattcttt aagttcatca tcagattttt tctctataga tttaggagag ccgtacatag
      721 taattctttc acactctgga aaaacttctt ttatatataa aataatatct cttaatttct
      781 ccattggtat tatcaatgca tctccatctg ctaagaatat tctttctaca tgcttataat
      841 atcttctaaa tatatcaatt tcatttttta ttacttctag tggctttatt ttaaattttt
      901 tagatttgta catactacaa aacgtacatt tgttatgaga acatcctagt gtgacttgta
      961 ttataagact ataagcctca cttggtggtc tgtaaagtgg catatcgtat tccatattaa
     1021 aatccccctt gtaataaaat attcattcta ttatattatt aatatttact ttaaataata
     1081 acttataaaa ttatattttt taaattttag tttaagatat attctttaaa aatttaatga
     1141 tactattggc agtaatatta agttgttttt cttgacttat aatagcatca ttatctccct
     1201 tttgttttcc ataatctcca aattgtgcat gatttcctcc ttcaatctca acataagttg
     1261 tatcatcagg aagtttttgt tttgattcta caagactttt aaaattgact actccatctt
     1321 tgctccccca tatagatata actttttttc ctaattcttt caactcatca cccattggat
     1381 aagaagctaa aaatacaacg ccttcaatta atttattatc acgtgcaaaa tttgatgctg
     1441 caactcctcc taatgaatga cctcctatta cccaatgttc tatgttgttg taagaatcca
     1501 taactttctg tgccttatta gttccaagta tagctagatt aagtggcatc tttacgatta
     1561 caacttcata tccactttct gctatttttc ttgcaagtgg agcataagat tctatttcta
     1621 ctttagctcc tggatacaaa attaaacctt tagaaacttt tcttcctttt ggtgtaaatg
     1681 aaatgttttc atttacagtt acttcaactt tactattgct gactagagct tcttttgcca
     1741 gcttttgagg ttcatatgtt ttatttatcc atatgaaaaa gccaagcaaa atcaatacaa
     1801 atagtatacc tattccctta aatatcttat tctttatgtt aaattttcta ttattatttt
     1861 tatcatcttt gttctcaacc tcatcataaa gtaaaggtct ctcaagttcc atagttatac
     1921 taaatgtatc atatttctta ttacgcttta cctttacatc tttactcata aatctaaccc
     1981 ccataatatt tgaatactat tatagtttat cctaagtaaa ttgttttttc aaccaatgaa
     2041 aaaaatcaat attttaacta ttttcatata aaattcataa atatatgttt tttgtttttt
     2101 atatattatt ttcttttagt attttataaa acaaatagcc atatacttta ttttaaatat
     2161 atggctattc tataatttaa tatctaagct gcttctttta ttgaaacttt agttatatta
     2221 cttattctat acatttcttt gacaccattt agagtttgca gtaagtttag acatattatc
     2281 ttgtcaccta gacttttagt atttataata ctctctaaaa ttacacttct tccttcatca
     2341 tacttatcta cattgtaatt tgaaatataa ttagtatctc tcaatatttt ttcaacatct
     2401 tcatctttta ttttattttt attaacattt atatatagat tatacatatt acttattagt
     2461 aatttctgat tttctaaaaa atcctcttga tgtttatctt tatatatagc atttatcaac
     2521 ataagtctat cttcaataag tgatggtatc aataataaat tttttatata gtaaacatca
     2581 gctacatttt ctatagactt attgacttca tcaattatat ttttaactat tcctttatac
     2641 atttctataa catgttgata gcctgtttta gcatcatatg gtaatataaa cttatttact
     2701 attaatgcaa taattgctcc taatgctaca tatgaaatcc tgcttatggt taaaacattt
     2761 gggtctccca taactactgc tgaaccaaga gctgaaacag ttacacatac cattaatttt
     2821 ctataatcaa ctacataaga gtttatatac cctgctaaaa gaactattaa cgaccttaat
     2881 gtactatctt ttattattga aaataataca ataaatatta cagctcctat aaatgtacct
     2941 tctattcttt ttctagacct ttgtatacaa ttttctgcgt aaggttgtgt taatgaaaag
     3001 acagttaaca ttatccatct tccatctctt aaatggaaat aatccataat aaaacccgct
     3061 acagctgtag ctaaagcaat ctttactgca taagaaaatc ttatagaatt taaattaaag
     3121 tttttcttat atattgatag tcgtttaaat tcatgaggta tctttgattt tctttcagct
     3181 ttcttttcgt ctcttgattt tactttttta taatctacta aaaactcata taaattttct
     3241 aaaacactat aaatttcttt taaatttata tttttagtat cctgagcaat aacataatct
     3301 ctaaatccta atatctcttt atcagttatg gtatctttat tttctaaaca catcttaata
     3361 tagtttattt ctttcgttgc tacaactaga acatctgatt tactatttat gctactttct
     3421 tctaaaatat tttttatatc ttcatcttca aattctttac tatccttttt gtatctttct
     3481 aggattaaac ttattctttc taatgaaaat aaaatattca ttatgtctat acctctaata
     3541 ctgatataaa agtcatcttt tctattatca aaaataacca ttttcaaatt tttagatata
     3601 gaatttattc tataattaca gctatctatt tttctcatac tagatttaat tatagaacta
     3661 tcatcattaa tagtattttt taaaagacta attttttcta ataattcatc acatatagat
     3721 atcagttctt tatctccgac atttttcatc ctatttctat tcataacaaa ttgagcaatc
     3781 attattataa ctgctccaac agctaaagcc gacaatctca taggaaattc actttttcct
     3841 acaggtatac ttaccataaa tatatacatt agaccaaagg gtacatatac tgctcttttt
     3901 aagtcataac taaatacata ccctattata aataatgcta taaaatttaa taaaactcct
     3961 aaatacatat tttgtactgc aaaaaatgat agtattccta agattatatt tattgctaaa
     4021 tacttcagta aatttttaat tggagaaata gttaaatctc tttccaagag cgttagcata
     4081 gctgttacta tacctacacc tataagtgta tttttacttc caaataaata tataaatata
     4141 gaaataaatg ctattataaa aataaacaac tttgtttttg atattactag tttctttgtc
     4201 atcatatccc ccctaaaaat ttcaacaaga ccaattttat catatttgtt atcttattca
     4261 aaatgcgctt ttttacggta ggactttaac tttttttata tttagaacta tataattcat
     4321 atataaacgt attttttata tatataaccg atatattttc gtatgctccc atattttttt
     4381 tgtttcaaat attttttcaa aaatataaaa ataactctct caacaatact aaaaatgcat
     4441 ttatcaagag agttataatt tatacaataa atttaattaa gcttttcttt acctaatata
     4501 taagttccaa gacccataaa taaagctcct ccaacaatat ttccaagtgt tacagctact
     4561 aaattataaa tagctcctcc aatagtaact gtatttattg ttggtgaaaa taatgaaaca
     4621 ctataaattg tcatatttgc tacactatgc tcaaagcctg atgttataaa agcaaataaa
     4681 cataagaata tcataattat ttttgcagta tcactattag ttctaaacga acacaacact
     4741 gatacacata ctagaatatt acataaaatc cctctaaaga aaagagctgt aaatggcatg
     4801 gatgctttac tagctgctgt atttgcaaaa aattcagcta caggtccttt gtctattaga
     4861 ccagttccta caaatataat gcctaaaacc aaagctccga ttaaattacc tacccaactg
     4921 tatgcccata ttttagaagt atcttttata cttacacctt tatttaacat accagcagac
     4981 ataaccatat tgtttccagt aaataactct gttcccgtca ttataaccaa acttagtgct
     5041 attgcaaatg ataaccccat tactatctta gtcataggtg aacctgcatc agtcaaaagt
     5101 cctccaatag taaatatcaa aagtatacct atacctacat aaagtcctgc aaacgcagaa
     5161 gataccaaat attttacttt acttgtgttt aataaattta tcttatttat agctgcatta
     5221 gttaatttat ccaaagtttc tttatgcata attccctctt ccttctatta aattttaatt
     5281 tattcaaata tatgttttac tcaatttata gatatttaat tccactccag tatatgtttt
     5341 cgtacatttt agttatttct ggaagctcta caccttcaag tgcccatttt ttaaattcca
     5401 taaatcctgt tctatcaatt atatatccta tatgttcttt tcctcctggt gcatctttat
     5461 ctatatactt ttctacatat ctataagtat taagtattat ctttattatg ctgtcctcat
     5521 ctacccataa aagaaaatct tctgctagtc tagggttttt ctttcctgtt ctacccatta
     5581 tagctaatct atagtatttt ttctcatctc tagtccatgc atttgttggg caatttagca
     5641 cacactctcc acagcctata cacttatctt tatctcttac caccttatta ttttctgttt
     5701 ttaatgctcc aacagatatc ttagaacatt tttttacaca tgctccacaa tttacacatc
     5761 tatccttttc atatattggt aaagccatac caataattcc aaagtcattc attctagctt
     5821 ttatacaatc atttggacaa ccagttaaag ccactttaaa atgtaaatca tttggaaata
     5881 tagctttttc tattctttta gcaaattcag ttgtattata ttgagccttt ggacagactt
     5941 tatttcctat acaagctgct atatttcttg tacctgctgc tggataacct gcgtttttct
     6001 cactttgatt tatattcatt ttttcaataa caggttgtat aattttattt atttcttcca
     6061 tatcttccat atttattcct aatatttcaa acccctgtct tgtagttatg tgcacctgtc
     6121 cattgccgta ctcacttgca attttagaaa ctacagctaa actctcaggg tcaataagac
     6181 ctccaggtac tctaactctt aaagaagtct catattttgt ttttgtaatt ctataagcat
     6241 ttttcattac ttttttggta tttaaatctc ttatcacaaa cttcaccccc taatcaataa
     6301 gatttttagc atatgaataa tcaaatactg gtccatctaa acatatgtaa gtatcatcca
     6361 ttttacaatg tccacattta cctattccac aacacatttt tctttcataa gaaacccaaa
     6421 tgttcttttc atctaaatct ctttttaaaa attcttctac tgtaaatttc atcatcattg
     6481 gaggtccaac tacaactata gaagtattgt ttatatcttt catatccaat tctggtatgt
     6541 attttgttac taatcctaca ttaccactat atccttcctc tgctccatct acagtaacta
     6601 aaatatcaag ttttttactc catctcttta aatcatctgc aaataaaata tcttttggtg
     6661 atttaaatcc tactattaat ttaaactttt cgcatttttc tttattatta taaaaatatt
     6721 caactattcc tcttacaggg gctaatgcac ttcctcctgc cactactaca atttctcttc
     6781 cttcataaag ggatacatca aatccatttc cataaggacc tcttataaaa aaagaatctc
     6841 cttctttata attaaacaac tcgctagtta cttttcctac atttcttatt gtaaagtcaa
     6901 tataatcctc tccatatcct gatactgata ttggactttc accgtattta ggtatagata
     6961 tctcataaaa ctttccaggc aatacacctt ttgtattgca gtttactcta aaagtccatt
     7021 ctttatcagt atgtttaact atatctagta tttttgcact tactggtata tatgggttca
     7081 tttatacttc ctccttacta attactaaat catttatttt ttctatacac tttgaaaatg
     7141 atatgtattg cggacaggca tcatcacatc ttccacagcc aacacacata tgatatccga
     7201 atcttttttt aaaatcatgt attttatgca tagttttaaa tctcattctt tcgccttgtt
     7261 tttttctaaa agaatttcca cctgctatat ctgtatatcc atctacttga caagaagccc
     7321 aaacccttct tctctcacct acattttcgt tttccttata gaaaatatcc tgcattgtaa
     7381 aacatgaaca tgttggacat acaaaattac atctaccaca tcctatacat cttgtatcat
     7441 attcatccca tattgaattt cctatcattt catttgaatc aatattctct ggcacatcta
     7501 cagatattaa attatcagtt acataatcaa cattaaattc agttgcttct ccattaaata
     7561 cttcaaattc actatccttt atatctaagt acagtgtatc tccttctata tttaatccaa
     7621 ttgaataatt atcagttttg ttagaatcca tgctcacaca aaaacagttt ctaaaacttt
     7681 ccttacaccc tacaagtgca aactttactt tatctctgat atttttataa aaataatctt
     7741 tttcttcacc attatttaga tatatttcat caagtctttt tataccattt atgtcacaag
     7801 ctcttaagaa aattaaaatt ttcttgttgt ctaaatcgct ttccttaaac tctttttcag
     7861 taaaataaaa caatacttga tttatgggaa gtacaacttc ttttggtgaa aagtttgctt
     7921 tcttagcaaa ttccatttct tcaaaagcgt ttacctcctt gtatcttata acatcagtat
     7981 ctgaaaaagt acctttaaat gggattaaaa ctggtgcaaa tatcttgtag tcttttttta
     8041 gataattcag accttcattg aacttagatg aatctaattt tagtttcatt tttatcacct
     8101 ttcttatatt ttagttttac ttacttgcta tcttgtttaa atcttaacac tttattttct
     8161 atgcttccgt gataattatc acagtttcaa aaataataaa aaaaatatta atggagttta
     8221 ttaagttctg ttaatatttt tttattatct acattattcg atttcaaatc taatcactta
     8281 aatacaatca ttaagtacaa taaaactact atctactcaa ttttttgaat aaaaaagaat
     8341 cttatttgtt tttttataca attcaatagg gtaaaataaa aattaataaa ttagacaata
     8401 aaaaagaatc tataaataga ttctcttaat aatattttta tttaattaaa attctaataa
     8461 tactcttact taatcataat taattatttt taaaatacct tgataattca gtttctttaa
     8521 cataaaaacc tttattgtca attttaataa gttcttcttt ttgcaatacc tttatcattc
     8581 tggaaacagt ctccctttta cagccaagca tatcagctaa atatgtaact gtaatattta
     8641 catttagtaa agtccattct ccacagcaaa ctccaaattc tctacttaac ctatataatt
     8701 ttgctgcaag ttttttatct acttttatgg atatagaatt tttcaactgt ctatataaac
     8761 gtcttattct tctttccata taagaaataa tatcctttgt aagttgaaaa tcattttgca
     8821 taatttctaa aaattcttca atactataat aagctacaat tgaattttca aatgcttcac
     8881 agccaacagt agagttttta gaagcgtcaa gtgtaatatc atttatgact tccccactat
     8941 ttaatatgaa aattactttt ctctctccat tttcacttat cttaaaaata gatacctttc
     9001 cttctaaaag tatataaaca ctgtctaagc tatctttttc ataaaataaa atttcttttt
     9061 tttgtaatct ttttagttta actttttctt taagttgatt cttcgtttta gtacttaaat
     9121 tattaaaaat tattacttta tcaatattat aatcttttaa tttagacatg taatatctct
     9181 ccattcctaa atttttaaga gagctctata aaacattaca aatttcttat tttattcatt
     9241 tttaaacaat tttatagcat ttgtagtttt aattttcctt tcaatagctt cattagaaag
     9301 ttcttttact acctgtgtat atactaaatc aataatgaaa aattgtgcta atttagaaga
     9361 tattgaacca gtttccagta ctgtttctcc cgatacataa gataagtgta catctgaaat
     9421 atcctttaat tcagaatttt tattttcagt aattgatata attttagcat tattggctct
     9481 tgcaagcttt acagttttta taatctcttc tgtttcacca gaatgtgaaa ttgcaattat
     9541 taaatctcct tcttccatta tggaagacat cattatcatt gtatgactac tgtcaaaact
     9601 tacacaatta agacctattc tcataaattt atagtttgaa tcctgtgcta ttataccaga
     9661 atatccaata cctatgaagt aaactttctt tgcatttatt ataagccttg cgcagtcatg
     9721 tacatcctta ctattgatta tctctactgt gttctctaaa gtggttacat ttgaacttaa
     9781 aagttttttt gctgtatcca aagctggctc atcattttgt atatttttat ttataatatt
     9841 ttttttattg atagttgata tttcttgtgc taaagtaact ttaaaatcct gtaatccatt
     9901 aaaattcatt ttttttacaa acctagttat agttgcttca ccaatattgc tctctttagc
     9961 tatttgtgat attggtttat aaaatacatc atctatattt tcttttatat aagctattaa
    10021 taatttatct gattttgtga ctttaaaagt tggtgattcc aattgttcta aaatactcat
    10081 taaaaaccct tctattcttt atattttgtt taaaaaatta tataatgctc caagcattcc
    10141 tgcatcattt tgtctctttg caaattctat attagtgttt ttgtaaactc tctctataag
    10201 aacctccttt aatgctttgt ctatttttgg ttttaggaac ttttcttgtg ccataatccc
    10261 accacctaaa attaccactt ctggatttat tacataacat atatttgcga ttccaactgc
    10321 taatgatttt atcatattat cgagttcttt taaacaatct tcatcattat tctttgctaa
    10381 atcaaaaatt atttttccat ttaagtcatt ttcattcaaa ttttttattt ttgctacttt
    10441 tttaattaga ctgctagtag atgccaattc ttgaaaagaa cttccattta cattcatata
    10501 tcctacttca ccagcactat tactaaaccc atttatcagt ttattattta ttataataca
    10561 tccaccaatt ccagtaccta ttgttaaaca tatagaagat gttgcatctt tacctgctcc
    10621 aagccacatt tcaccaagtc cagcacaatt aacatcattt tcaacttcac attttatatt
    10681 aaactctttt tctacttctt tttttaattg catgccctta tagtttggaa ttaattcttc
    10741 taatgcaaat agtattttac cttcaactgg gtcaaccata cctgcagttg atatacatat
    10801 accacttatt tcattttcct ctatatattt ttttactata tcttttattt tggctaatat
    10861 tccttctcca cctttttcct ttgcttcagt atcaagactt gatttatcaa ttataaatcc
    10921 atcttctcta ataaaaccat attttattga agtaccccca acatctatac aaacgtaatt
    10981 tttcataaca tatctccata caaattattt ttataaatta acaactctat ttaaaatttt
    11041 atattacaca aatcttttac ttatcttttc caattcacag atatatttcc ttgcttctga
    11101 taagtctata gtatcactta atacactttt ttctttggtt atatgatact tataaatatt
    11161 tttacataag tcctctccta acatattaag accttcttga gtgtaatgaa catcatcaat
    11221 agttaatcct ctgtcatgaa actgcatagc aattttgctt cctacacata atatatcaca
    11281 ttcactacaa gccgactcct gtgctgctgc aattcgtctt gttctaataa aatattcatc
    11341 ttctccaagc caataaccag ttaaacttac aaacatttta tcaatcatac attcttcttt
    11401 aagcctatac gcaatttttt ttagactttc tttatagtac aatacatcac taccatattt
    11461 tgcatcactt tcaccttgaa tccaaataac gtatttattt tctatattat aatgtttact
    11521 taaggtagta cagcctgtat taaatttttc tatagtgtca tttagaaacc agttattatc
    11581 atgattccag ttttttattc ttgaaccatc ttttgcattg tgaataaaac aaactttatt
    11641 tccagtaagc ttattccatt catttgaaaa tgcaggtgct atagtaccat caccttctga
    11701 agtctctagc tcacatctca tatttataat ttcatcagta ctcaaatatt caaaacaatt
    11761 ttcatttgga atgatgctct cttttggatt tcccaatcct ctagcattgc tttgtcctat
    11821 taataagaat acatctatat tttccataag ttaactcctt tacaaaattt taagctttta
    11881 attattttca attttctcat aaaaaactaa ggctgaaaat agtaatctaa ctaaaattta
    11941 cgaagtctca ctaatcgctg aaagttaaat cactattttc agccctagtg gttatataaa
    12001 ttatcattat ctaaccaaaa ccttaaaaat agcttttttg atattttctt tttctaaaac
    12061 ttttattcct gtcatatgag catcttccgg ataacaaact aaaaaatcac cttttctaag
    12121 ttccatgtat ccattatttt taccatcaag aggcaagaaa tcgccctttt cttcatatat
    12181 tttttgttct aaattttcta taaaatttat atctattcgt tcacatccat caagcatcaa
    12241 atgaacatct atatacttct tatgagcttc ccagaatcta tcttcttttt cacaagtttt
    12301 atactctaca atattcacaa aaatatcatc accatctatt gtataagtac ctttttcata
    12361 atctattaat gaattatctt tagcatattc aaaacatcta agtaaatctt catgcaatgt
    12421 tgaatatgtc ttactatgat ttatatttcc aaatatcata agcactatct ccctatataa
    12481 ttataaagtc tatttttata cttttatata caaagtatat tatacaatct tatagagtaa
    12541 ctaaattatt tatctaatca ctctataaga caatttatca tttaaatatt atttttcata
    12601 ataaacagta gtctcagctt ttggtaaaga tacttttgct ttaactttag cttctattgc
    12661 actaactatt gtacctacca ctacagaagt cgtgattgtt attagagaat atgcccaaga
    12721 agttacttct ggcatacggt attttaaata aacaactaaa attgctgata ctatgaatcc
    12781 aacatatgct cccattttag tcgctttttt acaaaatgca ccaagtacaa atattcctgc
    12841 taaaacacct agtactagcc ccataaaact attaaaccat tcatatgctg actttatttc
    12901 tccatttgct aatactattg caacagctat agaaagtata cctacaccta atgatatata
    12961 ttgtgctatc ttagtttgct tttccatact tatatctttt gttatgatag tttgtatatc
    13021 taaagtccaa cttgtagcaa ctgaattaag ccctgtcgat aaagttgatt gagaagctgc
    13081 atatatcgct gcaagtagta ttcctgttat acccactggt aattcataag ctatatatga
    13141 tgcaaatact tggtcttgtt gaactgtttg agctaaatct gggttttgag tatagtatat
    13201 aaataaacaa gttccaatta gataaaatac tgttgcaagt cccattgata aaacaccatt
    13261 tccatatgtc attttattaa gttgctttat atcagttgtt gtagtaaatc tttgaactat
    13321 gtcttgactc gatacatatg atgaaaaagt attaagacca gctccaacaa atattataaa
    13381 tgcacttgta gatagtatat ttttatcaaa cataacttca ttacttgcta agaacttgtg
    13441 tccagttgta agagtatcca ttactgttcc aaaaccacca tttatacttg ctattaaata
    13501 gaacaatgtc cctgtaacac ctactattaa taccattcct tgtataaaat cggtccacaa
    13561 gacagccttt aatccacctg tatatgagta aattattgct attacaccca taactattat
    13621 cagtacattt acaggtattc ctgtaagacc agccagaact attgatggaa gatacattat
    13681 gatagacata cgtcctattt gatatattat aaacatcaaa gctccaagta ctctaagacc
    13741 tttgctttcg tatctcattt ctaagtattc atatgctgta tctatttcta acctactata
    13801 tagaggtaag aaaaatttta ttgtcaaagg tattgctata aacataccta attgtgcaaa
    13861 ccacaaaatc caagtaccac cataagaatt tcctgctaat gataaaaatg atattggact
    13921 taataatgtg gcaaatattg atactgatgt aacccaccac ggaatagttc catcaccttt
    13981 gaagaactct tttcccttca tttccttttt tgaaaataac aatcctgcaa ataaaactgc
    14041 caataagtaa accactagta ttgcaaaatc tatccaagta aatcctacca tttgactaat
    14101 cctcccatac taaaagtatt ttattaaaaa tactttctgt atatttcttt tgctcttgat
    14161 ttcatttcat cagttgcttc tttcataggt tgtctacagt atccagcctc aacaccttgt
    14221 tcttcaagta gtaatttaat tgtttgatat aagccatttc ctaatatatc tgttattaaa
    14281 tcattagtca catgttgtac ttcaagtgct tctgatattt tttcattctt agttaattcg
    14341 aatatttgtc tagctctgac accgtttaca ttgaatgtag aaccaattgc cccatctaca
    14401 cctaaaactg tagctggtaa catcatttca tcaaatcctg caaatattaa tttatttggg
    14461 aatgtttttc tcattctctc taataagtag aaatctgctg ctgtaaactt aacacctatt
    14521 attttttcat tttcaaataa ttctccaaac tggtctaaac tcatatcaac accagttaaa
    14581 aatggtatag agtatattat taatctatta tctacagaat ttattattgt attataatag
    14641 tgttttattt cttcaaaatc aaatttatag taaaaaggtg taacagcact tattgcatca
    14701 tatcctaaat cagttgtaaa tttagcaagt tctacagctt cttttaaatt aactgaacca
    14761 acttgagcta ttaattttat ttcttctttc acttcatctt tagctatttc aaatattctt
    14821 ttcttttcat cagttgaaag catgaagttt tcccctgtac ttcctcctac ataaagacca
    14881 tctactttac aaacatctat attgtgtcta attatttgtc ttaacccttt ttcatttata
    14941 tttccttcct tatcaaatga aactaataat gctgaataaa ttcccttcat atctgttgtt
    15001 ctcatatctt tacctccaat tttaattttc aaatatagtt aaatataata attttttaat
    15061 ttataaatta atttttaatt aatttcaatt gctttaacaa atttttctgt tattaattgt
    15121 ggtcttgtta ttgctgaacc tactactgat gaatgaacac ccaactcaaa gacctttttt
    15181 aaatcttgag gagtatttac ctttccttca gctattacag gtatttctaa atctttaact
    15241 aatctttcca ttaatacaaa atctggacct tctaatgttt tagtatatgg agtatatcca
    15301 gatagtgtag ttgaaacgca atctacaccg tactcttgtg ctttgatagc ctcatcataa
    15361 tttgaaatat ctgccattac tagaacaccg ttttctttta tatactttat aagttctttt
    15421 aagtcttcat tatttggtct aactctattg gtagcatcta atgctatcat ttcacaccct
    15481 gttgttaaaa gttcatcaac ttctttttta gttggcgtta tatatatatc tgaatcttca
    15541 tagtttctct ttataatacc tataacagga agtccagtaa ctttttttat ttcaataata
    15601 tcttcaactc cttgagctct aattccaaca gctccacctt ccatagcagc cttagccatt
    15661 ctccccatta taaaaggact atgaagaggt tcatcttcta aagcttggca tgatactatt
    15721 aatcttccct ttaccttatc tagcattttt taaattacct cgtttctgaa atttattttc
    15781 ttgatttatg tattaataat aacatgaaaa ctttttcttt gcaatatttt ttcatatttt
    15841 tttctcgcat ctatattttt actgatttat tttatatatt agcttgtttt ttacatttaa
    15901 aagaaatttt atttcatttt tttggtgttt attttcattt tatataacta ctgttataag
    15961 tccatttaaa taatttcaat aaaaaaaccc atgtatacta tacataggtt tcccaatatt
    16021 attctaaatc cattataatt tttcttccac agcatggaca aaattcagcc tctgtatcta
    16081 tctcactttc acaataacca caaattataa aatcatcaca ttcattttcc aattcaaatt
    16141 ttttaccaca ttcagcacaa tatttatcat ttacatttcc aacataacca cactcacaag
    16201 ttacattact ttctgccatt tccatttcat taatttccat atttttttca taaattaact
    16261 tatcaagttc tagtaactca tcacagaatt tatcaaaact attatcatta atagaatctt
    16321 ctctaatttt ttgatatgtc agtattccca tttccaagaa tatctttgct ttcttttctt
    16381 gaatatcatc aatctctcta tttaattttg atttttcttt atataattca actttaaatt
    16441 ttccactacc aaactttttc ttaaccttag aaaatttatc atctacttta ttattagtat
    16501 ttccttccac agaaattccc tccaatcata tttaatcagc tgaatttagc ttatatccta
    16561 ttaaagatat cacaaaacta tatacaaatg aaattacaat agcttgtaag actttaaatt
    16621 gcattattaa agttgttcca taattagttg tattaaagaa attaatatta ctatctagta
    16681 taaatgtact aaataaagcc aatattccca tcaaaaatgc ataatatata ctaaatacta
    16741 ttataggtct tatactatct gtattatact taaatcttag cttgtatcca tttaataata
    16801 atattaacat agacaatgct cccattgcat aaaacattaa tttagtatct ccaaataaag
    16861 atgaagaact taaagtaaac attgatactg ttgagtttat tatggttact gaaattccat
    16921 ttgcaaaagc ccacatataa ctagctattt gtgggagtat agtaaataaa tttaatccat
    16981 ttgaataact actcatatct agttcattta agtaactact atcagatata gttagtacca
    17041 atagtattac taatactaaa acataaccta atatgaatgt tcttatagaa tttgaaaaaa
    17101 gagataaata catattttcc ttttcataac tttttttata agtagttatg tatgtacata
    17161 taaaccctaa tacaaatcca tttaaaagaa cactaaaaaa ttcataacta tattctaatg
    17221 catatccata ttctaacata ctatgtgaac tagtttttac attagtaaaa atagataaaa
    17281 tagctaaaac taatccataa aaaattccaa ctcctagaga atttgctaat acagtttttg
    17341 aatctctaca tctttttctc ataaaaatta ggtttgatat taataatacc aaaataggga
    17401 ttataagtaa tatcaacaaa cctatattgg catttataaa cccagaaccc atcatggtag
    17461 acatagatac actaatttga cccaagttga gagctaggat tatatgtgct ggatttatta
    17521 aataactaat atcattaaat tgaatagtta taatagcttt aaatatcaat gcaataataa
    17581 acaatataaa tatggttgta aatgttgtta aaaatacacc tcttttattt gcatgatatg
    17641 aaagctcttt tattttagat ttcaagtcta gttttgtttc aagtggtctt aatgatgcta
    17701 tttcataaag ttcatttcca caaaatttac agtaattatc cttagtatta ttttctttat
    17761 tgcaactaga acaaattttt tcttctttac ttttaagagt gatatggcta ttttttattt
    17821 ttctagttgg ttcacctgtc tttttggaat aattattatg tgaataattc atattattta
    17881 ttttcttttc acccattttt tccctccaag ttttactatt gtaaattatc aaatataact
    17941 atatcatata aaacttaatt ataccttaat tggatatatt tatctatttt atttgtttat
    18001 tgctgttgtt ttttaacagg tcttgatatt taaatagttt gttaatgcga actttattat
    18061 ttatatttta ttatgcttaa tttaaattta ttctattctt tattttcagt agtaaactat
    18121 ctgtaaatct taattataat aaagtattaa tcaataaagt tactcgacat tatctaataa
    18181 attttatcta tcacaatttt agattgttac acacaatata ttttgatata attaaatcat
    18241 aaacgaagta ttccaaatat ctaatgatag aaaggaatac ttatttttat gctttatttt
    18301 taatggaggc ttatatgaac ttagaaaaaa taaaaaaatt ttttggattt cctctagaca
    18361 aaaaacacaa agacaatgtt gagaaagaac tctgcaatta tctttatcat acgggtaaaa
    18421 tcatttgcat aataatagta atatctcaaa taattatgat gatatcaatc tcagctagag
    18481 aaggaggccc ttttgtcaca ccaagacgcc aatggtattt ttatatgtat gtaacactat
    18541 tttgtgtatc ttctgtcttt atgtttgtat tttcttacct ttggaataaa aaaaaggatt
    18601 gctgtacgtt ttatataaat ttatggataa tttatgtgac ttttttctgc ctatggggtt
    18661 gtgtaattac tctacttgac cagttaggtg gaaatgacct aagtgtattt agttatatta
    18721 tgttagcagc tgcagctttc tcagtattaa aatttggaga atcagtaata gtttttggag
    18781 gatgcttttt gtttcttaat ttattcttac ctgggattca aactatacca ggcaatgagt
    18841 ttagtaatat tgtcaacaca ttttttataa catcccttgc catttttgtt tctacaatgc
    18901 tatatagaaa tcgtgtattt acttactatg ataaactttt aattagtcaa caatatgaag
    18961 aaatatctca tataaataat ttacttaacg acaaagttat gacagatgac cttactaaaa
    19021 tgaacaaccg taggtacctt gaagatattc tacaaaaaaa attaatcagc catgcaaatc
    19081 aagaacctat aactggaatg atgatagata tagattattt taaacaattt aatgataatt
    19141 atggacatca aaagggagac tattgtctac aaaatattgc caaagtaatt ttagatttta
    19201 caagttctga aaatgaacat gctatacgat atggtggtga ggaatttttt atatgtattt
    19261 ttaactgtaa tgaggcagat gctaaactta aatcagaatg tttacgaaaa attatagagt
    19321 cctgcaattt tgagcgtgat gatgttcctt taaaatgtgt aactgttagt attggagttt
    19381 atacaaagaa aattggaaag acaataacat taaatgagtt tataagtaat tgtgataagg
    19441 ccctatatac tgcaaaagaa caaggacgta attgtgttgc attttattaa aaggttacat
    19501 actattacat aaacctataa gtattatatc gcaaaataaa agtaatcaaa ttatatattt
    19561 atagtacaat aaaaataact tgcatatctc taaaatagat aaatatgcaa gtcattttag
    19621 tgtttatact taaagttata taagttttat tatatataat tattaaaatt cagcattttt
    19681 aggagttctt gggaaaggta taacgtctct tatgttagac atacctgtca tatacataat
    19741 tattctttca aatccaagac caaatccaga gtgagtagca gtaccaaact ttctaagttc
    19801 taaataccac caataatctt cttctcttaa tcccatttca ttaattctat ctaacaatac
    19861 atcttctctt tcttctcttt gagaacctcc tacgatttct ccaactccag gaactagtaa
    19921 atccattgct ctaacagttt taccatcttc attcattctc atatagaaag cttttatatc
    19981 ttttggataa tctgtaacaa acactggaca attatatatt tgctccgtta tatatctttc
    20041 atgctctgtt tgaaggtcac atccccactc aacaggatac tcaaattcat gcccagattc
    20101 aattaataat tccactgctt tagtatacgt tattctaata aactcagagt ttactatctt
    20161 atttaatctt tctaacaatc ctttatctat aaaactatta aaaaattcca tttcttcagg
    20221 agcattttct aatacatagc ttataacata ttttatcata tcttctgcaa gttccatgtt
    20281 atcttcaagg tctgcaaaaa ctatttctgg ctctatcatc caaaattctg aagcatgtct
    20341 tcctgtataa gagttttcag ctctaaatgt aggtccaaaa gtataaacgt ttctaaaaga
    20401 aagtgccatt atctcggcat ttaattgacc actaactgtt aaattagcct cttttccaaa
    20461 gaaatcttga gtatagtcta ttttgccatc ttcagttttt ggaatatcat ttaaatccat
    20521 agttgttatt ctaaacatct ctcctgcacc ttcacagtca ctacctgtta tgattggaga
    20581 atgtgcatat acaaagtttc tttcttggaa gaatttgtgt attgcatagg cagctattga
    20641 tcttactcta aatacagctg aaaaagtatt acttcttggt cttaaatgtg ctatcgttct
    20701 taaatattca agcgtatgtc tcttcttttg tagtggatac gaactatctg attccccttc
    20761 tacaactatg ctttttgcat gtatttcgac tggttgttta gccccttctg tagatactaa
    20821 ctctccctct acaagtatag atgagcttat tgctaatttt cctacctctt taaaattttc
    20881 tactttctca tcaaatacta tctgcatatt tttaaagaag cttccatcat ttagctctat
    20941 aaatccaaaa tttttagata ctctagatgt tcttatccat ccagctactt ttacagtctt
    21001 ccctatgtaa tgttcttttt ctctgtacaa ttcttttact gttataaatt ccttttgcat
    21061 tttaaatcct cctagtataa ttgttattaa tttcttttaa atataatttc aataaaaaaa
    21121 gcccttcatc cctatataaa gggacgaaag actattactc tcgcggtacc accctagttg
    21181 tcataatgac ctcttagtta agcaatgctt aaagcctata acggtgcctt ccgtctaagt
    21241 ctacttacta aataagcttt cgattagaaa ctccaagatg ttcttcaata taaacctcgt
    21301 attgagcttt caccatcctc aactcgctag aactacattt tatatctact cttctcttca
    21361 cagtatttat cttttattat ttctgctaat taacaaaatt ataccaattt ataaattttt
    21421 agtcaataaa tttatataat tgatactgat tgttatttaa aatataataa ttctacctta
    21481 cataatgata ataaatactt atcttcatta cttctttatt acttcaattt ccaaaatttt
    21541 ataatttact tccattgtca acccagtctt ttgcttcttc gacaccctta attgaaggta
    21601 ttgaaacttt actatgaggt tttaattttt caacatcagc ccatgctgct gtcgactcat
    21661 ttccaactaa aagtgaactt ttaagtcttt tattatcttt accttttaat gctcttgcct
    21721 ttttactttc caaaactatc acctctatta tttattttgt aatagtttta gcaattttac
    21781 aaataaaatt cataagtcta aattataatt atttttaaat taacataata tcttttcaat
    21841 acttaattta tacctattta tatacaaaat atttactttg tgtattcaaa atataaaact
    21901 gttttttaat tttcatattt attttttatg ctatttttct actctatcta aagtatttga
    21961 tacaattaaa ctaataatca attataattt tacataggtt cttatctata gagtatttgc
    22021 tatctgttga atcgtatttt ttaaatttaa aatcccatat ccctgcgata catttggata
    22081 tgtatatatc tcaagttttg tagcacccaa tattaaatat gtttttaaaa cttgtgtaaa
    22141 caatgataat ctcggtacat tatcctgttt ttctaagtat tccatcaata aggctaaaac
    22201 acctgtgact atagaactgc tcactcctgt tcctgttcct gtattatatg ttccattttt
    22261 atatgtggat attatatcta cacctgaagc tactatatct ggcttaattc ctcttcctct
    22321 aattggtcct ttcgaagaac caatccacat actatcagtc ttattgttaa atgtaccaac
    22381 tgtaattaca tcatcactag cagcatacat agttatagta gctactgaat caggctctaa
    22441 aaaccttgtg tctggagcta tcaaattttt atttggcaag tatatgtcat attctccatt
    22501 tattataagt tctgaagtca atcttaaaat ccatactcca ggttttatat ctcttaatct
    22561 tatctccaaa ttttcttttc cagaggtaat atatggataa ataaatctca ttgcataagt
    22621 agtattttct aagttaaatt ttcctctata tatataaaag tctggagaat accttatatc
    22681 atgactaact tcacctgaag gagatattat ctgtgctccc actttatctg gaccattcgt
    22741 atttagtgtt atatcaagag catagtcatc tccatcttgt attattacat cttgaacttc
    22801 tcccacactg ctaaatctgc cagaataatg aatatctgta ttcccttgat ttcctgcacc
    22861 actcactact accacaccag cactactcaa tatattaaaa gtatctagta ttgaagtagt
    22921 tgctacagca cttgacttaa ctccaatagt caaatttatt atcagtggtt tattttctgt
    22981 tcttgctatg ttagtaacat acgttatagc tgctaaaaaa tctgaaacac tgtaatttat
    23041 ccttccagca taataagtat ctgtatatga ttttaattta actactatta agtctgattc
    23101 tgtagtaata cctctgtact gagaatttat ccttccattt ccaactaata taccagaaac
    23161 taaagttcca gtacctatat tatcttgact caaactccca tcatttctat ttatggctat
    23221 atttaactca cttcttgtaa attcacttcc aaaaataaaa ccttctggag gtggatttgt
    23281 atttgcttct tggtcccata aatataaaac tttactagtt ccatcatcat ttataaaatc
    23341 aggatgcaaa taatctatcc cagaatctat aactgctaat aaaattcctc tccctgttat
    23401 atcattatat ggattttcat aaatataatc agtttcagct gctgttgtaa tggtttctcc
    23461 attatttaca ttattagtta tttcaattag actgctcatt ggttcagatt cttcccacca
    23521 agcaacttgt attatattat ttaaaatagt ttcatcaaaa tctaaaggta catatattac
    23581 tgcaagctga ctatttaaaa ccatatacct atttattcca ttttcttgta gggcagattc
    23641 tatatcacct tgataaatta tacaataaga tttttccata aatccctcct atcttaaaac
    23701 atcaaacatt cctctaacat ccaagagccc atatccagaa tttgtatttg gatatactgt
    23761 gtttgaatct tttctagcac cagcttgcat aaaagttttt attttttgca catatgcttg
    23821 gtttggatat ctaccgtcaa caaaagtata ttgaaaatac attgcagcag caccagctgc
    23881 atgtgcactt gctgctgctg taccagttat agttgcatac gtgttcccag gataagcagc
    23941 tattatattg acacctggtg ctactatatc tggttttaac ctgtcttcaa tagttggccc
    24001 tcttgatgaa ctttgccata aactaccatt aatggtattg taggctccta tggttattaa
    24061 atcatcttga atcgcaggat aatttatagt gtaaaaaggg tctacctctc taaatctagt
    24121 tccacttttt aaaagttctc tatttggaag gtataagtta tatcttcctg ttataatata
    24181 aactcctact aatcgaatct tccatacacc tctttttgca ttctttaaag taacattagt
    24241 aaattgctgt ccagaaaaag ttgttgggta tatatatgtt atagaatatt cagtcccctc
    24301 taaatcaaat aaacctgtta ctttattata atttgaaatt ccaacacttt tactttcttc
    24361 accagtggga gatactatta ttacatcagc tttatctggt ctatttaacc aaagttctaa
    24421 tgataattct tcctcgtctt catttaactc taattcaact tcaacagaac ctccaacata
    24481 tggtattatt ccagatgtat gtgtctgtgt attgccctca tttcctgctc ctgccgttat
    24541 acataaccct ctagtaaaga acgctttttc actattactc ctattggtta aacctgctag
    24601 gctactggta cctaaagaca tatttataac taatggtctt ccaagttcaa aagctttttt
    24661 atatgcatac tgagatgcag caaacaacat tgcactatta taaaaatcat ctatcttgcc
    24721 gagttttatt attattagct cagaatcttc tgctatacct gcatattcac tatttacatt
    24781 tccaagccct gcacatatcc cactcaacat agttccttga ccaacttcat cctgagatag
    24841 actagggtca ttttctgcga tagctcgatt tatatcttct cgtgtatatt ctgtcccaat
    24901 ataaaaacca tcaggaggag ttccttcttt tgtttggtcc cataaatata ctatttttga
    24961 agtgccatct ggataaataa aatctgggtg tagatagtct attcctgtat ctgcaattga
    25021 tattagagtc cctcttcctg ttatattaat attaggatta tttttaaaga aatttacgcc
    25081 catttcttct gttgcaacta cacctccaaa agtacctcga ttaatttctc caagtaatgt
    25141 catctttgta gtcgatacag ttcttatgat tgaaggaagt tgcaaaactc gttgtatgct
    25201 attatagtct gtattattta tagatagtac acctaatgaa tcacttatct taaaaaacct
    25261 ttgactcata cctaacccag ctagttcttc ttcaaattca ggagtatgga ctatatctat
    25321 tcctgatagt attcctgatt gtctacttgc atttttactt atataaattt cattctctaa
    25381 gtcattatgt atttgcatat tataaccatc tataaactta taactatttt cctcatcttt
    25441 aaatgactta ttaatacttc tatatccaat atcctctgtt tctaaatctt gatttatatt
    25501 agatagagtg tacaaatcta tatctgataa atttaaaaaa ccaaatcctg atgaattatt
    25561 tggataagat tgattactta atctccttgc tccctttaga agtaatgccc ttaatttctg
    25621 tgaatacaaa aataaatcat ttccatttac aattccccat tccataaaca atgaacaaac
    25681 ccctgtaaca tgaggtgtag ccatgctagt tccagttaat gctccacttg tacctcctgg
    25741 taaaaaagat actatatctt cacctggagc taataaatca ggtttaaaaa cacctaattg
    25801 tgtatctcct tcaccagaaa atatagatac tatatctgtt cttgaattaa aactacctac
    25861 tgttataact ctacttgctg ttccaggaac tgttacagta agctcttgag taggaatcag
    25921 aaatctagta tttctattta gaccttcaga agttggcaaa tatatattta cattaccagt
    25981 tactatatct attggttcaa atacaatttt ccataaccca ggagttatct gtgtatttga
    26041 acttaattgt agagtaactc ttcttgtgag agaatacggt gctatagggt aaaaataacc
    26101 agttattcta gtttcaccca aagtattcct tatctcacct gaagttagag agattgcttg
    26161 tgtttgatta tttgatgggt ttaccaaatg tacactaaaa tcatcaacaa aatctggcca
    26221 tatatttatg tttaatatac gctctccttc cccaactata aactcaactt cttctgtaat
    26281 attattttga agcctaatcc ttttatgacc tcctttatct gcattatttc cagctgctac
    26341 aactatattg tttttccaaa ataaacacat atcatctata tattgttcaa ataaagatgt
    26401 tcctctatgt gaaccttcat tacttccata acttatattt aatgtaacag gcattcttaa
    26461 ttctaatgcc ctatctaaaa taaatttaat tgccctcata aactctgtac ttctcgaaaa
    26521 aatatcggtc tgtatatttc caactctaac cactattatt ctggcatcac ttgcaatagt
    26581 tgcacaaata cctgcaacat gtgttccatg taagctagtt gttgaaatag gtatatacat
    26641 acttccatct attgcattat ttatatcttc attagtatat aatgttcctt ctctaaaacc
    26701 ttctggtgga tttccttgaa tagattggtc ccaataatat aatatcttag accttccatc
    26761 actatctcta aacacaggta gagtataatc tattcccgaa tcaattatac caattatagt
    26821 tccttttcca gttaaaccag ttctattttt aaatcctgtt attcctgtac ttgaaaaact
    26881 ttgcacatcc tgagtctgta atataaaagg cttttctata aattcaattt ctggataagt
    26941 taaaagtata tttacatctt cttcattact tgatgttatt attgcatatg atgaattaag
    27001 tatctctact gatacaccta attcttcttc taacctcaat atatctccat tgtattttac
    27061 aattaattca taatttatta taatcacctc gacttctaaa attattatta atgtatatgt
    27121 tttgtgtgag tctaaaatgt attagactat ataatttttt aagtttcagt tatacaattt
    27181 ataatagata tattaaaaaa ataaataatg atggtacaat tttgaataaa tcataccatc
    27241 atttatattt actttatctt gaaaccatta aatttttcaa tgctttctca agacctttta
    27301 cagtcaatgg aaacatatta aattcacttt gtatcattct ttgagtttga taccaataac
    27361 taattgaatc ccatccatct ctaagttctg gattcatcca tacaatttta ctgtactttc
    27421 tcttaaacct tttaagccac tctataccag gtgtataatt atatggacca cgatagttac
    27481 caccaatatg aagcaactca gaaggcgaca tagaagcatc tccaacaatt ataactttat
    27541 agtttttatc tatatttttt aatatccatt cagtattaat agatttactt aaccaacatt
    27601 caggtgttgt aaataatcta tcataaatac agttatggaa ataatatatc tttacatctt
    27661 taaaatgatt tgatttactt acagactgaa ataatgtatt acataaagtg ctataccctc
    27721 tcattgaacc acctgaatcc ataagcaata aaagcttcac tgtatttttt cttggcttct
    27781 caaaaaataa ctttaaatat cctgcattat tacaagtctc ttcaatagtc ttatccaaat
    27841 caagctctgt ctttggagca tctattctag tagaaaattg acgaagtctc tttagtgcaa
    27901 cttgaaattg acgcatattt aaaacttcat catctctaaa atctctgtat tttctttctc
    27961 ctgcaacttc aagaacagct ctaccataag tagaatttcc acctatacgt ataccagttt
    28021 gcccttttcc tgaatgtcct aactctgaag tgcctcctgt gcctatccaa taattaccac
    28081 cattatgagg agaatcttgt tcttttattc gttcctccaa tttagctctt aatttatcaa
    28141 gatttatatt tggattttgt tctaatcttt caaactcttc taaatctata tctggttttt
    28201 taagccaatt cataatctct tctggaattt cttcttggtg ttctatacct ttaaaatact
    28261 ccaaaaacac tgcatcaaac ttatcaaaat cactttcact ttttattaaa atcatcctgc
    28321 aaagatagta aaaatttgaa aagtttgaat agcacagtcc tttatccaat gcttcaatta
    28381 aagtcatcca ttcatttaaa gatacattta atcctcttga cctcaataaa taaaaaaatt
    28441 caataaacat aattatccag ctcctattaa ctataagtgt ctttgcatag attcaatatc
    28501 ctcattattc ttaagtagta ttcctgcaaa aggaacttct ttttctattt tttcaatagg
    28561 cattccactc aaagttaatg cttgtatcca gtctattaac tctgatgtac taggcttttt
    28621 ttgtatgtcc tttaaacttc taatccaata aaaagtagtc attacttgtt ccaataggtg
    28681 ttcttctact ttatcaaaat gtactttaac tatttcttcc atcatgtctc tatcaggaaa
    28741 ttctatataa tgaaatatgc atcttcttaa aaaagcatct ggaagttctt tttccgcatt
    28801 tgaagttata ataactattg gtctttgttt agctcttaca gtttcttttg tctcatttat
    28861 gtaaaactcc attttatcca attcccaaag caagtcattt ggaaattcta aatccgcctt
    28921 atctatttca tctattaaaa gaattacttg ttgatttgag ctaaaggcct ctcctagttt
    28981 accatatttt atgtacttgc taatatcatc tacaccttct cctccaaatt ggctatcata
    29041 aagtctttga acagtatcat atacataaag cccttcttgt gcttttgtag ttgattttat
    29101 attccaaatt actaaatctt tttttaattc atttgaaatt gcttgtgcta gcatagtttt
    29161 acctgttcca ggttcgccct taatcaaaag tggcttttca agagcaatag caacattaac
    29221 tgatgccatc aattctggtg atactacata atcactactt cctctaaagt tagatatctc
    29281 tttttttatc ataaatccta ctccttttaa acagtatttt ctaaatgtat atagacttta
    29341 ttactatttt tgatataaaa ataataa
//
LOCUS       DAMJWC010000049        28964 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMJWC010000049 DAMJWC010000000
VERSION     DAMJWC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28964
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.049"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            116..670
                     /gene="tcdR"
                     /locus_tag="PC503_002527"
     CDS             116..670
                     /gene="tcdR"
                     /locus_tag="PC503_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF2528493.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            988..8088
                     /gene="tcdB"
                     /locus_tag="PC503_002528"
                     /gene_synonym="toxB"
     CDS             988..8088
                     /gene="tcdB"
                     /locus_tag="PC503_002528"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF2528494.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8210..8710
                     /gene="tcdE"
                     /locus_tag="PC503_002529"
     CDS             8210..8710
                     /gene="tcdE"
                     /locus_tag="PC503_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF2528495.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            9015..9221
                     /locus_tag="PC503_002530"
     CDS             9015..9221
                     /locus_tag="PC503_002530"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528496.1"
                     /translation="MKLFKNTKIRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKT
                     LKKYKICLQITIRQSPYLIEESIN"
     gene            9438..17570
                     /gene="tcdA"
                     /locus_tag="PC503_002531"
                     /gene_synonym="toxA"
     CDS             9438..17570
                     /gene="tcdA"
                     /locus_tag="PC503_002531"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF2528497.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17905..18603)
                     /gene="tcdC"
                     /locus_tag="PC503_002532"
     CDS             complement(17905..18603)
                     /gene="tcdC"
                     /locus_tag="PC503_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HDF2528498.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19029..19274
                     /locus_tag="PC503_002533"
     CDS             19029..19274
                     /locus_tag="PC503_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF2528499.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19492..19761)
                     /locus_tag="PC503_002534"
     CDS             complement(19492..19761)
                     /locus_tag="PC503_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2528500.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(20639..21376)
                     /locus_tag="PC503_002535"
     CDS             complement(20639..21376)
                     /locus_tag="PC503_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528501.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21388..22149)
                     /locus_tag="PC503_002536"
     CDS             complement(21388..22149)
                     /locus_tag="PC503_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528502.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22149..23063)
                     /locus_tag="PC503_002537"
     CDS             complement(22149..23063)
                     /locus_tag="PC503_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528503.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23234..23941
                     /locus_tag="PC503_002538"
     CDS             23234..23941
                     /locus_tag="PC503_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528504.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            23986..25392
                     /locus_tag="PC503_002539"
     CDS             23986..25392
                     /locus_tag="PC503_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2528505.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            27153..27542
                     /locus_tag="PC503_002540"
     CDS             27153..27542
                     /locus_tag="PC503_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2528506.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            28412..28882
                     /locus_tag="PC503_002541"
     CDS             28412..28882
                     /locus_tag="PC503_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2528507.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
BASE COUNT        11503 a         3168 c         4478 g         9815 t
ORIGIN      
        1 ttcatataaa atttaattta tttgccgatt atataattat aatgactgat ttaattccaa
       61 tgttgtcaaa attttcaaat aaatcatcat tataaatata agagaggatg attttatgca
      121 aaagtctttt tatgaattaa ttgttttagc aagaaataac tcagtagatg atttgcaaga
      181 aattttattt atgtttaagc cattagtaaa aaaacttagt agagttttac attatgaaga
      241 gggagaaaca gatttaataa tattttttat tgaattaata aaaaatatta aattaagtag
      301 cttttcagaa aaaagcgatg ctattatagt caaatatatt cataaatcat tactgaataa
      361 gacttttgag ttgtctagaa gatattctaa aatgaagttt aattttgtag aatttgatga
      421 aaatatctta aatatgaaaa ataattatca aagtaagtct atttttgagg aagatatttg
      481 ttttttcgga tatattttga aagaattatc tggtattcaa agaaaagtta ttttttataa
      541 atatttaaaa ggatattctg atagagaaat atcagtgaaa ttaaaaatat ctagacaagc
      601 tgttaataag gctaaaaata gagcatttaa aaaaataaaa aaagactatg aaaattattt
      661 taacttgtaa ttaatgagtt taaagaaata tttacaatag aaatcaaatt ttataattaa
      721 ctttattgta aaattaataa cttaatctaa gaatatctta atttttatat tttatataga
      781 acaatgttta catatttatt tcagacaacg tctttattca atcgaagagc aaattaatca
      841 actgagtgtc ttaaatttaa aatgttagga agtgaatgta tatgaaaacc taagtagata
      901 ttagtatatt ttataaatag aaaggaggat atataaaaga gttttagcat ttagatgtaa
      961 aaatattata gtaaaggaga aaattttatg agtttagtta atagaaaaca gttagaaaaa
     1021 atggcaaatg taagatttcg tactcaagaa gatgaatatg ttgcaatatt ggatgcttta
     1081 gaagaatatc ataatatgtc agagaatact gtagtcgaaa aatatttaaa attaaaagat
     1141 ataaatagtt taacagatat ttatatagat acatataaaa aatctggtag aaataaagcc
     1201 ttaaaaaaat ttaaggaata tctagttaca gaagtattag agctaaagaa taataattta
     1261 actccagttg agaaaaattt acattttgtt tggattggag gtcaaataaa tgacactgct
     1321 attaattata taaatcaatg gaaagatgta aatagtgatt ataatgttaa tgttttttat
     1381 gatagtaatg catttttgat aaacacattg aaaaaaactg tagtagaatc agcaataaat
     1441 gatacacttg aatcatttag agaaaactta aatgacccta gatttgacta taataaattc
     1501 ttcagaaaac gtatggaaat aatttatgat aaacagaaaa atttcataaa ctactataaa
     1561 gctcaaagag aagaaaatcc tgaacttata attgatgata ttgtaaagac atatctttca
     1621 aatgagtatt caaaggagat agatgaactt aatacctata ttgaagaatc cttaaataaa
     1681 attacacaga atagtggaaa tgatgttaga aactttgaag aatttaaaaa tggagagtca
     1741 ttcaacttat atgaacaaga gttggtagaa aggtggaatt tagctgctgc ttctgacata
     1801 ttaagaatat ctgcattaaa agaaattggt ggtatgtatt tagatgttga tatgttacca
     1861 ggaatacaac cagacttatt tgagtctata gagaaaccta gttcagtaac agtggatttt
     1921 tgggaaatga caaagttaga agctataatg aaatacaaag aatatatacc agaatatacc
     1981 tcagaacatt ttgacatgtt agacgaagaa gttcaaagta gttttgaatc tgttctagct
     2041 tctaagtcag ataaatcaga aatattctca tcacttggtg atatggaggc atcaccacta
     2101 gaagttaaaa ttgcatttaa tagtaagggt attataaatc aagggctaat ttctgtgaaa
     2161 gactcatatt gtagcaattt aatagtaaaa caaatcgaga atagatataa aatattgaat
     2221 aatagtttaa atccagctat tagcgaggat aatgatttta atactacaac gaataccttt
     2281 attgatagta taatggctga agctaatgca gataatggta gatttatgat ggaactagga
     2341 aagtatttaa gagttggttt cttcccagat gttaaaacta ctattaactt aagtggccct
     2401 gaagcatatg cggcagctta tcaagattta ttaatgttta aagaaggcag tatgaatatc
     2461 catttgatag aagctgattt aagaaacttt gaaatctcta aaactaatat ttctcaatca
     2521 actgaacaag aaatggctag cttatggtca tttgacgatg caagagctaa agctcaattt
     2581 gaagaatata aaaggaatta ttttgaaggt tctcttggtg aagatgataa tcttgatttt
     2641 tctcaaaata tagtagttga caaggagtat cttttagaaa aaatatcttc attagcaaga
     2701 agttcagaga gaggatatat acactatatt gttcagttac aaggagataa aattagttat
     2761 gaagcagcat gtaacttatt tgcaaagact ccttatgata gtgtactatt tcagaaaaat
     2821 atagaagatt cagaaattgc atattattat aatcctggag atggtgaaat acaagaaata
     2881 gacaagtata aaattccaag tataatttct gatagaccta agattaaatt aacatttatt
     2941 ggtcatggta aagatgaatt taatactgat atatttgcag gttttgatgt agattcatta
     3001 tccacagaaa tagaagcagc aatagattta gctaaagagg atatttctcc taagtcaata
     3061 gaaataaatt tattaggatg taatatgttt agctactcta tcaacgtaga ggagacttat
     3121 cctggaaaat tattacttaa agttaaagat aaaatatcag aattaatgcc atctataagt
     3181 caagactcta ttatagtaag tgcaaatcaa tatgaagtta gaataaatag tgaaggaaga
     3241 agagaattat tggatcattc tggtgaatgg ataaataaag aagaaagtat tataaaggat
     3301 atttcatcaa aagaatatat atcatttaat cctaaagaaa ataaaattac agtaaaatct
     3361 aaaaatttac ctgagctatc tacattatta caagaaatta gaaataattc taattcaagt
     3421 gatattgaac tagaagaaaa agtaatgtta acagaatgtg agataaatgt tatttcaaat
     3481 atagatacgc aaattgttga ggaaaggatt gaagaagcta agaatttaac ttctgactct
     3541 attaattata taaaagatga atttaaacta atagaatcta tttctgatgc actatgtgac
     3601 ttaaaacaac agaatgaatt agaagattct cattttatat cttttgagga catatcagag
     3661 actgatgagg gatttagtat aagatttatt aataaagaaa ctggagaatc tatatttgta
     3721 gaaactgaaa aaacaatatt ctctgaatat gctaatcata taactgaaga gatttctaag
     3781 ataaaaggta ctatatttga tactgtaaat ggtaagttag taaaaaaagt aaatttagat
     3841 actacacacg aagtaaatac tttaaatgct gcatttttta tacaatcatt aatagaatat
     3901 aatagttcta aagaatctct tagtaattta agtgtagcaa tgaaagtcca agtttacgct
     3961 caattattta gtactggttt aaatactatt acagatgcag ccaaagttgt tgaattagta
     4021 tcaactgcat tagatgaaac tatagactta cttcctacat tatctgaagg attacctata
     4081 attgcaacta ttatagatgg tgtaagttta ggtgcagcaa tcaaagagct aagtgaaacg
     4141 agtgacccat tattaagaca agaaatagaa gctaagatag gtataatggc agtaaattta
     4201 acaacagcta caactgcaat cattacttca tctttggggg tagctagtgg atttagtata
     4261 cttttagttc ctttagcagg aatttcagca ggtataccaa gcttagtaaa caatgaactt
     4321 gtacttcgag ataaggcaac aaaggttgta gattatttta aacatgtttc attagttgaa
     4381 actgaaggag tatttacttt attagatgat aaaataatga tgccacaaga tgatttagtg
     4441 atatcagaaa tagattttaa taataattca atagttttag gtaaatgtga aatctggaga
     4501 atggaaggtg gttcaggtca tactgtaact gatgatatag atcacttctt ttcagcacca
     4561 tcaataacat atagagagcc acacttatct atatatgacg tattggaagt acaaaaagaa
     4621 gaacttgatt tgtcaaaaga tttaatggta ttacctaatg ctccaaatag agtatttgct
     4681 tgggaaacag gatggacacc aggtttaaga agcttagaaa atgatggcac aaaactgtta
     4741 gaccgtataa gagataacta tgaaggtgag ttttattgga gatattttgc ttttatagct
     4801 gatgctttaa taacaacatt aaaaccaaga tatgaagata ctaatataag aataaattta
     4861 gatagtaata ctagaagttt tatagttcca ataataacta cagaatatat aagagaaaaa
     4921 ttatcatatt ctttctatgg ttcaggagga acttatgcat tgtctctttc tcaatataat
     4981 atgggtataa atatagaatt aagtgaaagt gatgtttgga ttatagatgt tgataatgtt
     5041 gtgagagatg taactataga atctgataaa attaaaaaag gtgatttaat agaaggtatt
     5101 ttatctacac taagtattga agagaataaa attatcttaa atagccatga gattaatttt
     5161 tctggtgagg taaatggaag taatggattt gtttctttaa cattttcaat tttagaagga
     5221 ataaatgcaa ttatagaagt tgatttatta tctaaatcat ataaattact tatttctggc
     5281 gaattaaaaa tattgatgtt aaattcaaat catattcaac agaaaataga ttatatagga
     5341 ttcaatagcg aattacagaa aaatatacca tatagctttg tagatagtga aggaaaagag
     5401 aatggtttta ttaatggttc aacaaaagaa ggtttatttg tatctgaatt acctgatgta
     5461 gttcttataa gtaaggttta tatggatgat agtaagcctt catttggata ttatagtaat
     5521 aatttgaaag atgtcaaagt tataactaaa gataatgtta atatattaac aggttattat
     5581 cttaaggatg atataaaaat ctctctttct ttgactctac aagatgaaaa aactataaag
     5641 ttaaatagtg tgcatttaga tgaaagtgga gtagctgaga ttttgaagtt catgaataga
     5701 aaaggtaata caaatacttc agattcttta atgagctttt tagaaagtat gaatataaaa
     5761 agtattttcg ttaatttctt acaatctaat attaagttta tattagatgc taattttata
     5821 ataagtggta ctacttctat tggccaattt gagtttattt gtgatgaaaa tgataatata
     5881 caaccatatt tcattaagtt taatacacta gaaactaatt atactttata tgtaggaaat
     5941 agacaaaata tgatagtgga accaaattat gatttagatg attctggaga tatatcttca
     6001 actgttatca atttctctca aaagtatctt tatggaatag acagttgtgt taataaagtt
     6061 gtaatttcac caaatattta tacagatgaa ataaatataa cgcctgtata tgaaacaaat
     6121 aatacttatc cagaagttat tgtattagat gcaaattata taaatgaaaa aataaatgtt
     6181 aatatcaatg atctatctat acgatatgta tggagtaatg atggtaatga ttttattctt
     6241 atgtcaacta gtgaagaaaa taaggtgtca caagttaaaa taagattcgt taatgttttt
     6301 aaagataaga ctttggcaaa taagctatct tttaacttta gtgataaaca agatgtacct
     6361 gtaagtgaaa taatcttatc atttacacct tcatattatg aggatggatt gattggctat
     6421 gatttgggtc tagtttcttt atataatgag aaattttata ttaataactt tggaatgatg
     6481 gtatctggat taatatatat taatgattca ttatattatt ttaaaccacc agtaaataat
     6541 ttgataactg gatttgtgac tgtaggcgat gataaatact actttaatcc aattaatggt
     6601 ggagctgctt caattggaga gacaataatt gatgacaaaa attattattt caaccaaagt
     6661 ggagtgttac aaacaggtgt atttagtaca gaagatggat ttaaatattt tgccccagct
     6721 aatacacttg atgaaaacct agaaggagaa gcaattgatt ttactggaaa attaattatt
     6781 gacgaaaata tttattattt tgatgataat tatagaggag ctgtagaatg gaaagaatta
     6841 gatggtgaaa tgcactattt tagcccagaa acaggtaaag cttttaaagg tctaaatcaa
     6901 ataggtgatt ataaatacta tttcaattct gatggagtta tgcaaaaagg atttgttagt
     6961 ataaatgata ataaacacta ttttgatgat tctggtgtta tgaaagtagg ttacactgaa
     7021 atagatggca agcatttcta ctttgctgaa aacggagaaa tgcaaatagg agtatttaat
     7081 acagaagatg gatttaaata ttttgctcat cataatgaag atttaggaaa tgaagaaggt
     7141 gaagaaatct catattctgg tatattaaat ttcaataata aaatttacta ttttgatgat
     7201 tcatttacag ctgtagttgg atggaaagat ttagaggatg gttcaaagta ttattttgat
     7261 gaagatacag cagaagcata tataggtttg tcattaataa atgatggtca atattatttt
     7321 aatgatgatg gaattatgca agttggattt gtcactataa atgataaagt cttctacttc
     7381 tctgactctg gaattataga atctggagta caaaacatag atgacaatta tttctatata
     7441 gatgataatg gtatagttca aattggtgta tttgatactt cagatggata taaatatttt
     7501 gcacctgcta atactgtaaa tgataatatt tacggacaag cagttgaata tagtggttta
     7561 gttagagttg gggaagatgt atattatttt ggagaaacat atacaattga gactggatgg
     7621 atatatgata tggaaaatga aagtgataaa tattatttca atccagaaac taaaaaagca
     7681 tgcaaaggta ttaatttaat tgatgatata aaatattatt ttgatgagaa gggcataatg
     7741 agaacgggtc ttatatcatt tgaaaataat aattattact ttaatgagaa tggtgaaatg
     7801 caatttggtt atataaatat agaagataag atgttctatt ttggtgaaga tggtgtcatg
     7861 cagattggag tatttaatac accagatgga tttaaatact ttgcacatca aaatactttg
     7921 gatgagaatt ttgagggaga atcaataaac tatactggtt ggttagattt agatgaaaag
     7981 agatattatt ttacagatga atatattgca gcaactggtt cagttattat tgatggtgag
     8041 gagtattatt ttgatcctga tacagctcaa ttagtgatta gtgaatagat aaaaatatgt
     8101 taaatatatc ctcttatact taaatatata aaaataaaca aaatgataca ctacataaag
     8161 tgttctatct aatatgaaga tttaccaata aaaaggtgga ctatgatgaa tgcacagtag
     8221 ttcacctttt tatatttcta atggtaacaa aatatttttt tatataaacc taggaggcgt
     8281 tatgaatatg acaatatctt ttttatcaga gcatatattt ataaagttag taattttaac
     8341 tatatcattt gatacattat taggatgttt aagtgcaata aaaagtcgta aatttaattc
     8401 tagttttgga atagatggag gaatcagaaa agtagcaatg atagcatgta tatttttttt
     8461 atcagtagtt gacattctta caaagtttaa ctttttattt atgttaccac aagattgtat
     8521 caatttttta agactaaaac atcttggaat atctgaattt ttctctattt tatttatttt
     8581 atatgaaagt gtaagtatat taaaaaatat gtgcttatgt ggattaccag tacctaagag
     8641 attaaaggaa aaaatagcaa ttttactaga tgcaatgaca gatgaaatga atgctaagga
     8701 tgaaaagtaa gtaatggtag atataataaa gatattaaca aataaaaagt gttatccaaa
     8761 taagaatagc tgaaagttat cataattcat gaaactaata atgaaaacga gggagcagat
     8821 gccaagagac acacaagtat taaatacata taatttcgaa gcaagtgttc attactatat
     8881 agatgacaag gtagtatatc aaacattggt tcacaaagat ggtgcatggt cagttggtaa
     8941 aatctattaa gctacattag ttacagatat cacaaactat aatagttaaa catagaaata
     9001 tgtgtaaatt gtgattgaaa ttattcaaaa acacaaaaat acgtgatgaa ggacaaaatg
     9061 atatagaaaa taagtatcaa accttaataa atgatttaat tgatagttta aaagttatag
     9121 gaaaaatata taaagaaata aaaacattaa aaaaatataa gatatgttta caaattacta
     9181 tcagacaatc tccttatcta atagaagagt caattaacta attgagtatc tttaaattga
     9241 aatgttagga agtgatttaa atatgaaaac ttaaattata aaaaatcaat attaatttat
     9301 ttttaaaaaa tagaaaggag tgtataagat ttattttcaa agtttaaaaa caagaaaatc
     9361 aatttaaatt tcagaaggaa taaatgtggt tatagaagtg gatttattat caaaaataat
     9421 aatactagga ggtttttatg tctttaatat ctaaagaaga gttaataaaa ctcgcatata
     9481 gcattagacc aagagaaaat gagtataaaa ctatactaac taatttagac gaatataata
     9541 agttaactac aaacaataat gaaaataaat atttacaatt aaaaaaacta aatgaatcaa
     9601 ttgatgtttt tatgaataaa tataaaactt caagcagaaa tagagcactc tctaatctaa
     9661 aaaaagatat attaaaagaa gtaattctta ttaaaaattc caatacaagc cctgtagaaa
     9721 aaaatttaca ttttgtatgg ataggtggag aagtcagtga tattgctctt gaatacataa
     9781 aacaatgggc tgatattaat gcagaatata atattaaact gtggtatgat agtgaagcat
     9841 tcttagtaaa tacactaaaa aaggctatag ttgaatcttc taccactgaa gcattacagc
     9901 tactagagga agagattcaa aatcctcaat ttgataatat gaaattttac aaaaaaagga
     9961 tggaatttat atatgataga caaaaaaggt ttataaatta ttataaatct caaatcaata
    10021 aacctacagt acctacaata gatgatatta taaagtctca tctagtatct gaatataata
    10081 gagatgaaac tgtattagaa tcatatagaa caaattcttt gagaaaaata aatagtaatc
    10141 atgggataga tatcagggct aatagtttgt ttacagaaca agagttatta aatatttata
    10201 gtcaggagtt gttaaatcgt ggaaatttag ctgcagcatc tgacatagta agattattag
    10261 ccctaaaaaa ttttggcgga gtatatttag atgttgatat gcttccaggt attcactctg
    10321 atttatttaa aacaatatct agacctagct ctattggact agaccgttgg gaaatgataa
    10381 aattagaggc tattatgaag tataaaaaat atataaataa ttatacatca gaaaactttg
    10441 ataaacttga tcaacaatta aaagataatt ttaaactcat tatagaaagt aaaagtgaaa
    10501 aatctgagat attttctaaa ttagaaaatt taaatgtatc tgatcttgaa attaaaatag
    10561 ctttcgcttt aggcagtgtt ataaatcaag ccttgatatc aaaacaaggt tcatatctta
    10621 ctaacctagt aatagaacaa gtaaaaaata gatatcaatt tttaaaccaa caccttaacc
    10681 cagccataga gtctgataat aacttcacag atactactaa aatttttcat gattcattat
    10741 ttaattcagc taccgcagaa aactctatgt ttttaacaaa aatagcacca tacttacaag
    10801 taggttttat gccagaagct cgctccacaa taagtttaag tggtccagga gcttatgcgt
    10861 cagcttacta tgatttcata aatttacaag aaaatactat agaaaaaact ttaaaagcat
    10921 cagatttaat agaatttaaa ttcccagaaa ataatctatc tcaattgaca gaacaagaaa
    10981 taaatagtct atggagcttt gatcaagcaa gtgcaaaata tcaatttgag aaatatgtaa
    11041 gagattatac tggtggatct ctttctgaag acaatggggt agactttaat aaaaatactg
    11101 ccctcgacaa aaactattta ttaaataata aaattccatc aaacaatgta gaagaagctg
    11161 gaagtaaaaa ttatgttcat tatatcatac agttacaagg agatgatata agttatgaag
    11221 caacatgcaa tttattttct aaaaatccta aaaatagtat tattatacaa cgaaatatga
    11281 atgaaagtgc aaaaagctac tttttaagtg atgatggaga atctatttta gaattaaata
    11341 aatataggat acctgaaaga ttaaaaaata aggaaaaagt aaaagtaacc tttattggac
    11401 atggtaaaga tgaattcaac acaagcgaat ttgctagatt aagtgtagat tcactttcca
    11461 atgagataag ttcattttta gataccataa aattagatat atcacctaaa aatgtagaag
    11521 taaacttact tggatgtaat atgtttagtt atgattttaa tgttgaagaa acttatcctg
    11581 ggaagttgct attaagtatt atggacaaaa ttacttccac tttacctgat gtaaataaaa
    11641 attctattac tataggagca aatcaatatg aagtaagaat taatagtgag ggaagaaaag
    11701 aacttctggc tcactcaggt aaatggataa ataaagaaga agctattatg agcgatttat
    11761 ctagtaaaga atacattttt tttgattcta tagataataa gctaaaagca aagtccaaga
    11821 atattccagg attagcatca atatcagaag atataaaaac attattactt gatgcaagtg
    11881 ttagtcctga tacaaaattt attttaaata atcttaagct taatattgaa tcttctattg
    11941 gtgattacat ttattatgaa aaattagagc ctgttaaaaa tataattcac aattctatag
    12001 atgatttaat agatgagttc aatctacttg aaaatgtatc tgatgaatta tatgaattaa
    12061 aaaaattaaa taatctagat gagaagtatt taatatcttt tgaagatatc tcaaaaaata
    12121 attcaactta ctctgtaaga tttattaaca aaagtaatgg tgagtcagtt tatgtagaaa
    12181 cagaaaaaga aattttttca aaatatagcg aacatattac aaaagaaata agtactataa
    12241 agaatagtat aattacagat gttaatggta atttattgga taatatacag ttagatcata
    12301 cttctcaagt taatacatta aacgcagcat tctttattca atcattaata gattatagta
    12361 gcaataaaga tgtactgaat gatttaagta cctcagttaa ggttcaactt tatgctcaac
    12421 tatttagtac aggtttaaat actatatatg actctatcca attagtaaat ttaatatcaa
    12481 atgcagtaaa tgatactata aatgtactac ctacaataac agaggggata cctattgtat
    12541 ctactatatt agacggaata aacttaggtg cagcaattaa ggaattacta gacgaacatg
    12601 acccattact aaaaaaagaa ttagaagcta aggtgggtgt tttagcaata aatatgtcat
    12661 tatctatagc tgcaactgta gcttcaattg ttggaatagg tgctgaagtt actattttct
    12721 tattacctat agctggtata tctgcaggaa taccttcatt agttaataat gaattaatat
    12781 tgcatgataa ggcaacttca gtggtaaact attttaatca tttgtctgaa tctaaaaaat
    12841 atggccctct taaaacagaa gatgataaaa ttttagttcc tattgatgat ttagtaatat
    12901 cagaaataga ttttaataat aattcgataa aactaggaac atgtaatata ttagcaatgg
    12961 aggggggatc aggacacaca gtgactggta atatagatca ctttttctca tctccatcta
    13021 taagttctca tattccttca ttatcaattt attctgcaat aggtatagaa acagaaaatc
    13081 tagatttttc aaaaaaaata atgatgttac ctaatgctcc ttcaagagtg ttttggtggg
    13141 aaactggagc agttccaggt ttaagatcat tggaaaatga cggaactaga ttacttgatt
    13201 caataagaga tttataccca ggtaaatttt actggagatt ctatgctttt ttcgattatg
    13261 caataactac attaaaacca gtttatgaag acactaatat taaaattaaa ctagataaag
    13321 atactagaaa cttcataatg ccaactataa ctactaacga aattagaaac aaattatctt
    13381 attcatttga tggagcagga ggaacttact ctttattatt atcttcatat ccaatatcaa
    13441 cgaatataaa tttatctaaa gatgatttat ggatatttaa tattgataat gaagtaagag
    13501 aaatatctat agaaaatggt actattaaaa aaggaaagtt aataaaagat gttttaagta
    13561 aaattgatat aaataaaaat aaacttatta taggcaatca aacaatagat ttttcaggcg
    13621 atatagataa taaagataga tatatattct tgacttgtga gttagatgat aaaattagtt
    13681 taataataga aataaatctt gttgcaaaat cttatagttt gttattgtct ggggataaaa
    13741 attatttgat atccaattta tctaatacta ttgagaaaat caatacttta ggcctagata
    13801 gtaaaaatat agcgtacaat tacactgatg aatctaataa taaatatttt ggagctatat
    13861 ctaaaacaag tcaaaaaagc ataatacatt ataaaaaaga cagtaaaaat atattagaat
    13921 tttataatga cagtacatta gaatttaaca gtaaagattt tattgctgaa gatataaatg
    13981 tatttatgaa agatgatatt aatactataa caggaaaata ctatgttgat aataatactg
    14041 ataaaagtat agatttctct atttctttag ttagtaaaaa tcaagtaaaa gtaaatggat
    14101 tatatttaaa tgaatccgta tactcatctt accttgattt tgtgaaaaat tcagatggac
    14161 accataatac ttctaatttt atgaatttat ttttggacaa tataagtttc tggaaattgt
    14221 ttgggtttga aaatataaat tttgtaatcg ataaatactt tacccttgtt ggtaaaacta
    14281 atcttggata tgtagaattt atttgtgaca ataataaaaa tatagatata tattttggtg
    14341 aatggaaaac atcgtcatct aaaagcacta tatttagcgg aaatggtaga aatgttgtag
    14401 tagagcctat atataatcct gatacgggtg aagatatatc tacttcacta gatttttcct
    14461 atgaacctct ctatggaata gatagatata tcaataaagt attgatagca cctgatttat
    14521 atacaagttt aataaatatt aataccaatt attattcaaa tgagtactac cctgagatta
    14581 tagttcttaa cccaaataca ttccacaaaa aagtaaatat aaatttagat agttcttctt
    14641 ttgagtataa atggtctaca gaaggaagtg actttatttt agttagatac ttagaagaaa
    14701 gtaataaaaa aatattacaa aaaataagaa tcaaaggtat cttatctaat actcaatcat
    14761 ttaataaaat gagtatagat tttaaagata ttaaaaaact atcattagga tatataatga
    14821 gtaattttaa atcatttaat tctgaaaatg aattagatag agatcattta ggatttaaaa
    14881 taatagataa taaaacttat tactatgatg aagatagtaa attagttaaa ggattaatca
    14941 atataaataa ttcattattc tattttgatc ctatagaatt taacttagta actggatggc
    15001 aaactatcaa tggtaaaaaa tattattttg atataaatac tggagcagct ttaactagtt
    15061 ataaaattat taatggtaaa cacttttatt ttaataatga tggtgtgatg cagttgggag
    15121 tatttaaagg acctgatgga tttgaatatt ttgcacctgc caatactcaa aataataaca
    15181 tagaaggtca ggctatagtt tatcaaagta aattcttaac tttgaatggc aaaaaatatt
    15241 attttgataa tgactcaaaa gcagtcactg gatggagaat tattaacaat gagaaatatt
    15301 actttaatcc taataatgct attgctgcag tcggattgca agtaattgac aataataagt
    15361 attatttcaa tcctgacact gctatcatct caaaaggttg gcagactgtt aatggtagta
    15421 gatactactt tgatactgat accgctattg cctttaatgg ttataaaact attgatggta
    15481 aacactttta ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt acctctaatg
    15541 gatttgaata ttttgcacct gctaatactt ataataataa catagaaggt caggctatag
    15601 tttatcaaag taaattctta actttgaatg gtaaaaaata ttactttgat aataactcaa
    15661 aagcagttac cggatggcaa actattgata gtaaaaaata ttactttaat actaacactg
    15721 ctgaagcagc tactggatgg caaactattg atggtaaaaa atattacttt aatactaaca
    15781 ctgctgaagc agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatacta
    15841 acactgctat agcttcaact ggttatacaa ttattaatgg taaacatttt tattttaata
    15901 ctgatggtat tatgcagata ggagtgttta aaggacctaa tggatttgaa tattttgcac
    15961 ctgctaatac ggatgctaac aacatagaag gtcaagctat actttaccaa aatgaattct
    16021 taactttgaa tggtaaaaaa tattactttg gtagtgactc aaaagcagtt actggatgga
    16081 gaattattaa caataagaaa tattacttta atcctaataa tgctattgct gcaattcatc
    16141 tatgcactat aaataatgac aagtattact ttagttatga tggaattctt caaaatggat
    16201 atattactat tgaaagaaat aatttctatt ttgatgctaa taatgaatct aaaatggtaa
    16261 caggagtatt taaaggacct aatggatttg agtattttgc acctgctaat actcacaata
    16321 ataacataga aggtcaggct atagtttacc agaacaaatt cttaactttg aatggcaaaa
    16381 aatattattt tgataatgac tcaaaagcag ttactggatg gcaaaccatt gatggtaaaa
    16441 aatattactt taatcttaac actgctgaag cagctactgg atggcaaact attgatggta
    16501 aaaaatatta ctttaatctt aacactgctg aagcagctac tggatggcaa actattgatg
    16561 gtaaaaaata ttactttaat actaacactt tcatagcctc aactggttat acaagtatta
    16621 atggtaaaca tttttatttt aatactgatg gtattatgca gataggagtg tttaaaggac
    16681 ctaatggatt tgaatacttt gcacctgcta atactcataa taataacata gaaggtcaag
    16741 ctatacttta ccaaaataaa ttcttaactt tgaatggtaa aaaatattac tttggtagtg
    16801 actcaaaagc agttaccgga ttgcgaacta ttgatggtaa aaaatattac tttaatacta
    16861 acactgctgt tgcagttact ggatggcaaa ctattaatgg taaaaaatac tactttaata
    16921 ctaacacttc tatagcttca actggttata caattattag tggtaaacat ttttatttta
    16981 atactgatgg tattatgcag ataggagtgt ttaaaggacc tgatggattt gaatactttg
    17041 cacctgctaa tacagatgct aacaatatag aaggtcaagc tatacgttat caaaatagat
    17101 tcctatattt acatgacaat atatattatt ttggtaataa ttcaaaagcg gctactggtt
    17161 gggtaactat tgatggtaat agatattact tcgagcctaa tacagctatg ggtgcgaatg
    17221 gttataaaac tattgataat aaaaattttt actttagaaa tggtttacct cagataggag
    17281 tgtttaaagg gtctaatgga tttgaatact ttgcacctgc taatacggat gctaacaata
    17341 tagaaggtca agctatacgt tatcaaaata gattcctaca tttacttgga aaaatatatt
    17401 actttggtaa taattcaaaa gcagttactg gatggcaaac tattaatggt aaagtatatt
    17461 actttatgcc tgatactgct atggctgcag ctggtggact tttcgagatt gatggtgtta
    17521 tatatttctt tggtgttgat ggagtaaaag cccctgggat atatggctaa aatatatgtt
    17581 tgataaaaaa ttattcctgt gctactaaga aattattttt atataataaa tattgagatt
    17641 taattaaaag tcatgtgtta ttgtaataca tgacttttag ttaaaatttt tctatcattt
    17701 aataatctat tattcttgac tattttataa taaaattcat atatggaaat attaatacta
    17761 aataattaat agttgataaa aaatagataa tatgctaaaa gcaaaaacta atttagagcc
    17821 ttgtaactgt ttatttgcaa ttataaaaac atctttaaac atattgacta taatataaaa
    17881 tattaactat aatacaaaac aatattaatt aattttctct acagctatcc ctggtatagt
    17941 tatatttcca cccatagttg attcataagt tatagttcca gcacttatac ctcttatagt
    18001 tatgtaatca tcctctaata ctcttgaagg agttattgat tttttataac tacatagtac
    18061 aaccttatca taatttccag acacagctaa tcttatttgc acctcatcac catcttcaat
    18121 aacttgaata accttacctt caaattttac ctttttgtac ttataatcat caggtgttct
    18181 agctaattgg tcataagtaa taccagtatc atatcctttc ttctcctctt cttctttttt
    18241 gcgttgttct tcagcctttt tagcttcttc agctttttta gcttcttcag ctttacgttg
    18301 attttcagct tcaatagctt tcttttcgtc gtctttcatt ttgaaccatg gttcagcatc
    18361 agacaatttg ctatttaaag tttctatttc tgttttttga gaatctataa ctgatgtttg
    18421 gttagaaatg acctcctcat ggtcttcaga acaagctggt gaggatatat tgccaaaaaa
    18481 cacgcctaaa ataaatgcca gtagagcaat accctttgtg ctcttaaaga atttaattat
    18541 tttcttagag cttccttttc cttcattact aaattcgtta ccctcatttt ttttagaaaa
    18601 cataatacaa tctccctttt attagatata ttttatttta aaagttaaaa acttaaaata
    18661 actagttgac taaaaattat atattcatat tttcctaaaa tatatttccc ctaagcataa
    18721 ttttacaaaa taaagtaaga agattcaata tattttgaaa aaataagata aaaatgtcag
    18781 attataatat aattttcttg aaggtgaatt ttatatatta aattaaacat aaagtatttt
    18841 atttgtataa aactatatta tgatgtaatt aagtgactca gtgatttaga ggtggtaaaa
    18901 tatatatata tgaaagagca taaataaatt gatataataa aaaattaaat attaaatatt
    18961 aactataata aaaaaatatc tggtaatagg tataatataa aaagaatata ccagaaagaa
    19021 ggtgaagtat gggagaacta caaaaaattc caggggtagg gaaagcaaca gaaaaatctt
    19081 taatcatgtt aggatataca actattaaat cacttaaaga tgcaaaccca gcacaaatgt
    19141 atgaaaagga atgtttaatg cgtggacagc acatagacag atgtcagtta tatgtataca
    19201 gatgtgcagt atattttgca tcaactgaaa atccagaacc agaaaaatta aagtggtggt
    19261 attggaaaga ttaaaaaatc aaaaaagtta gacataaaaa agagttgaat atccgtttta
    19321 aataataaaa actaatactc aactcttttt tagtcgtaaa ttttatgtaa atctatttgt
    19381 atggctaaat atacccatca ataaatgtat aaatatacta atcaacaaat gactaaacat
    19441 actacctaac aaaggattaa ataaattcct taacaaagca ttctaaaaca attaattaga
    19501 aactgtttct tcaagccatt ttctacattg ctcaatattt accatagggt caaaaccttg
    19561 gtcttttccc ttatttaaaa gcatatcaca agggaaagta tcacattcac cacaatgatt
    19621 aagttcctta ctttcacagc aagttttaac cttacattct ccaccccaaa atggtttttc
    19681 catagttggg caaccagtgc aatttacttg ttcttttttt gtacaactgt cacaacagac
    19741 accacatctt gattcaaaca tattcaaaca tcctttccat tatttaaaaa tattataaaa
    19801 tgattttaga tgaatacaaa agtgcaaata gttgatttta ggtcatctaa atgttaaaca
    19861 taaaattatt agtactggta aatttataaa aactattcca aaaatctttt tgaatatttc
    19921 aaaacacaat aaattacttc aaatcccctt gaatatattt tacagcatta tagattgctt
    19981 taaatctctt tgaatattct acaagactat agattagttt aaatcccttt gaatatattt
    20041 tacaacatta tagattgttt taaatctctt tgaatattct acaagactat agattagttt
    20101 aaatcccttt gaatatttca aaacaccata gattacttta aatccctttg aatgttctat
    20161 aacactataa attactttta acttttatat aaccataaag tttttatctg gcactttaaa
    20221 tggagtttta tatcaaattt gccttccatc gaataaccaa acttaattta attacacatt
    20281 ccaagagtca aatattcatt caatatattt gataattcta tgttatagct ataattaaat
    20341 atagattatt aaagttaaat atttatttaa tatattgaat gattttttac ctatatttaa
    20401 ttaagtttca ttatataata taaaaattgt ttttgcatta agttttaata taatacataa
    20461 taattttaaa taataacatt attatatatt tttaaatttt aggagtatat ctattatata
    20521 gcgagtagat aaaacatata aaattcaaat aaaagatata tatttttaaa taaaatggat
    20581 atagatttca actaaaaaga atataaattt caaacccaaa aatatctagc atttaccatt
    20641 aagaaataac atcattcttt ctaaaatttc tattggcaat ttcagaaaat actatagtag
    20701 taataaatgc aacacatatt gtaactatag tgtcattaac atttaaagca gattgcttta
    20761 taacccccat agcactacct aacatagaat aagggaaaaa tataccaaca gcaggttttg
    20821 ctactattaa tcccatacca aatagagaaa ggcaaagact aataccaata ggagttgcaa
    20881 aacttctaat ctttatagac atgtataatt gtatagaagc tattgaaata gaaataatcc
    20941 aacctttagc aatccaacca gtcaattctt taggtacact accagaaaaa ccaaacatat
    21001 ttcctgcaac tatataaaag ataacaaaga aaacttgtgt aatagctgta agtattgaaa
    21061 ctactgtaag tttagataaa aagatatttt ttaaattaac tggcagtgtc attacattat
    21121 tccaattatg attcatatgt tcaagcctac aaatatatgc acaaaagatt gcgattaaga
    21181 taggaaagaa aaattcccca taaaaaagac taacttgagt ccataagctg taccattctt
    21241 ttttgagtat gccttgattt agataaaaat taccagaacc aatcaacaca cttataagtg
    21301 gcaaagctaa taatacatac catataaaag aattttttaa ctttagaatt tctcccaaaa
    21361 ctgacttcct taacatttaa atccctccta tacttctttt tttaataaat gatttcttcc
    21421 aatataataa attagcattc caattaagaa aactaaaatc gtaatagaaa aattcatatc
    21481 aattctatag acagatgaac ctaaaacatt atcataagca taacttaaag gtgataactc
    21541 taggtaataa gaccatataa acaatctacg aataccttga taaaacaaac ctgatgtcaa
    21601 acctataaaa ctaccaatca tgccaaatgt aattgcaatc atttgatttg gaattacagt
    21661 tgcaatccat aggtgtagtg caatgatagc aatacttaca agaattgttc ctaatgtgta
    21721 ttttaaaagt aaagatacag aaattgactc aataacccct ctaaaatgtc caaacaacac
    21781 aatagataac acttgcatca atacaggtat agataccaaa atagcagaac ataaaaattt
    21841 agataaataa atactattta aagatgtcac agaagatttt aaaagcttcc atgtatctcc
    21901 tttatgttct atatcgctta tacgtgatgt aattattgat attaagatag gaaagaatag
    21961 accatttaaa cttgcaaaac tcataagcat ataggaatat tcaaatccac ctaacatatc
    22021 tggattacgt gtaatagctc tatttgaatt tacgatacac cacattattt caacagctgc
    22081 aaataaaaag gtcatcagaa taatcttctt tcttttaagt ttataaaatt ctagaccaag
    22141 gtatttcatt ataaagtcac cgccttacca gtaagttcta agaatatatc ttccaagctt
    22201 tttttatgtt cttctattct aaatacatct atatttgaat ggacaagcat accatttatt
    22261 ttagcgacat ctgagtcttt taaattttca atagtcaagt acccatcttg tataagtgac
    22321 atatatcctt tagtatttaa tagtttttgt gcagatacaa cattcttagt tttgatagca
    22381 atctgacttt gacctctatt atgaagttct tttatgctat cttgaaaaac cagttcgcca
    22441 tgatttatta ttcctattga tgtggcaatt tggtcaattt cacttaaaag atggctagag
    22501 attagaacag tcatcccgta tttttctggt agagatttta ttaattctct aatttcctca
    22561 atccctgctg ggtcgagtcc atttgtaggt tcatcaagta ttaataattt gggaaacttc
    22621 attattgcca tagcaatgcc aagacgttgc ttcataccta aagaatattg actaactttt
    22681 ttattttttt gattttctaa ccttacaatt tttaatgctt catttacatt ttttttaggt
    22741 aaatctaaga gtctttgcat tatggtcatg ttttcaagcc ctgtaagatg accatagtat
    22801 gatggagatt ctatcaaaga acctatatct tttaaaattg atattctatt tttttcattt
    22861 aactctttac ctaaaatatt aatatttcct tgtgtgggtt tagcaagtcc aagaagcatt
    22921 ttaagagtgg tagattttcc agctccatta ggacccaaaa aaccatatac agctccttgt
    22981 ggaactctta ggtctatatc ctttactcta aatattttat tgtattcctt tgaaagtctt
    23041 tgtgttctaa ttatcatttc catatgtttc atcccctttt ttaatctgtg cttattgatt
    23101 cttttaactt atatcagtat aataacttgg ttacatttca attagctgaa atttacctta
    23161 caataacctt aaaagtctat ttaggcaaag ttgtgaaaat gggtatatgg tatactaaag
    23221 gagggtgatg attatggagt caataaaaga taaaaaaata cttgtggttg atgaccacaa
    23281 ggaattatta aaaatgatag atgaaatcct gagaaaagag ggatttagta gagtattttt
    23341 agcatcaagt tatgaggaag ctgttagggt atttagaaat gtaaagccag attgtgcaat
    23401 tttagatgtt gtattgccag atggagatgg tttttctatt atgagaaaaa ttagagagac
    23461 atctaaaata ccagtgattt ttctctctgc aagaggtgaa gatgaagata gattgattgg
    23521 tttgggctta ggggctgacg attatatagt aaagccattt ttaccaaagg aacttacttt
    23581 aaggcttgtg ggtatattaa atcgtgtata tgtgcctata gaagaagagg agttgccagt
    23641 atttaaactg ggagattctg ttgttgtgaa tttaaatagt gcatgtgttg agaaagatgg
    23701 gcaagagatt tctttaacag ctaaagagca ttcgttgctt ttaaagttgt atgaaaataa
    23761 agggagaatt gttactaatg attcactatg tcaagccatt tggggagatg atatgtatgg
    23821 atatgaaaat acccttatgg ttcatgttag aagggttaga gagaagatag aaaaaactcc
    23881 atctacacct aaacatctta ttacagtaag aggtcttgga tataagttga tgattaatta
    23941 attttagata ttagaataaa agaaatcaag aggagtgatt taattttgga tagtgtaaag
    24001 tacatattga ggcgatttat aggttcaagt atcttgattt cattactttt tattgtatta
    24061 aatatagcag gttttcttct gttttcatat atgttatttg tatctaaata ctctgataat
    24121 ttagatacaa gtgatagtag agaaataaaa tcaaacttga ttatgattga agataatttg
    24181 attttaagag atggaaagtt tattttagat gattctagta aggaagtact acataaaaat
    24241 aaagtttggg caatgttaat tgataacaat ggagatagaa tatggggatt tgatttacca
    24301 aaagaaattc caagtcatta tactttgaca gatgtagcaa agttttcaag gttcttttta
    24361 aaggactatc ctgtgtatgt atgggaacat ccaaatggaa tattagtaac aggttatcca
    24421 aaagacaagt atactaagtt taaccttact tatacggtta aggaaataga acaatttcct
    24481 atgttaataa taggtatgtt tctggttaat gcaatagtta cttttttaat agctctattc
    24541 ataggtttaa aaatggtgaa atctataaaa ccaattatta ctggcataaa gcttatgtca
    24601 aaaggagaac cagtactttt acaagaaaaa ggaatactaa gtgatatttc aaaatctatt
    24661 aatactgtat ctaaagagtt gcaaatgaaa gatgaaaaac ttaggaagaa agaggaagct
    24721 aggtctaact ggattgcagg aatatctcat gatataagaa ctccactttc aatgataatt
    24781 ggatatgctg gagaacttga agaaagcagt agcctttcaa atagagaaca agagcaagtg
    24841 tctattatat gcaatcaagg gattaaaatc agagaattag taaatgacct aaatttagtg
    24901 tctaaacttg aatataatat gcaaacattg aattgtgata agattagagt ttctgcgttt
    24961 ttgagagagc ttatttctga gtttataaat aataatttgg ataatgactt ttacgttgaa
    25021 cttgatatac taaatgaaga tattattata gatgcagata aaaaattatt aaaaagggct
    25081 attagtaatt taatacaaaa tagtataact cataaccaac aaggatgtaa tataagggtt
    25141 acctctaagt ctgatttaga tttttgctat ataattgttg aagatgatgg aaaaggtatg
    25201 agtcaagaaa gaattaatag tttattaaag agccaaaatg gactaagtga ggcatatgcc
    25261 aaaggtcaaa atcatggtct aggtattttg atagtatctg gcattattaa tgcacataga
    25321 ggtaaattag atattacgag cattgatagt cagggactaa aaacaatact aaaattacct
    25381 ctaattaagt gatattttat aaaataataa cagataagaa tgaagaatga aaatattttg
    25441 aaaataattt tattctttat tgacaaatta actctattag agtagaataa ggataaattc
    25501 ttttcttgtc aagttttatt aaagtaaaga gtaacttgtg ctttatgcgc ttatggctga
    25561 gttactcatg gtatcaaaat tttcatagaa ataatatttt ggaattattg taaggttatt
    25621 aaattcttta gataattcca ttttttttat tttttagtta atatttaatt ttattattga
    25681 caaaaaaatt ctactaaaat agaattatgg tatagtgttt tttaatttta agaaaaaata
    25741 taatgacatc ctaaaaaagt tttaattata agctgttctg tgtagttata atagcttcta
    25801 tgtaactatt gtaagtatat tttattatag ttatttattt aaagtacgat aaatgtttta
    25861 aattgaagta ttttgcgcca ttgagttcta ctaaagtaga gtttttgtgt agtattttta
    25921 gaaataacat atatatatat gtatttatgt tgaaatatat ggaaaattta taatataatt
    25981 aatgaaaaaa tttaaacttt gtaatatata aataaaaaaa ctctaaaata gaaggatata
    26041 attatataga atgtttcaat taaacaaggt aaaaactata atcttaaaat taaaattaac
    26101 attattctta agaagcaaga aatttagaaa gtaggaagtt tagtgataag tggtagtaag
    26161 taagaaattt aggaagtggg aagtttagtt ataagtggta gtaagtaaga aatttaggaa
    26221 gtgggaagtt tagttataag tggtagtaag taagaaattt aggaagtggg aagtttagtt
    26281 ataagtagta gtaagtaaga aatttagtaa gtgggaagtt tagtagtaat aatttatagc
    26341 aagtaagaaa tttaggaagt aggaagttta gtaataattt gtagcaagta agaaacttag
    26401 ggagtaggaa gtttagtaat aatttatagc aagtaagaaa tttagggagt aggaagttta
    26461 gtaataattt gtagtaagta agaaatttag aaagtaggaa atttagtaat aatttatagt
    26521 aagtaagaaa attagggagt aggaagttta gtaataattt atagtaagta agaaatttag
    26581 aaagtaggaa gtttagtaat aatttatagc aagtaagaaa tttagggaga ggaagtttag
    26641 taataatttg tagcaagtaa gaaatttaga aagtaggaag tttagtagta atttatagta
    26701 agtaagaaat ttagtaagtg agaagtttag ttataattta tagtaagtaa gaaatttagt
    26761 aagtgagaag ttcagtaata agttgtagta aataaaaagt ttaggaagta ggaagttcag
    26821 taataagttg tagtaaataa aaaatttagg aagtaggatt tactgaaata caaatattta
    26881 aaatcaaaga gtttaaaaga aaggagagct actggacaag tatccaaaat agatagctga
    26941 gtacaaaata tttcataaaa ttaagcaata taatacaaga gaattttgac attatttata
    27001 tatatttacc gtgtacaaat agctaaattt aggattaaga ttgaaaaata tcttataagt
    27061 ctgagcttat ataaatccgt ataagatgta tttaatcgaa aaattttatt atggatattg
    27121 cttgtctata ttctgagtag caaggtttta tcatgactat aaaaaagttg ccacaatcag
    27181 aattaaagat aatgaaattt atatggaaat cagattccaa agtaacatct agagatattg
    27241 ttttaggaat ggagcaaaaa tatcaatgga aacaaacgac aactttgact cttttatcta
    27301 gattagtagt aaaaagattt ctaaattctc aaaagataga taaatatacg cattatgaag
    27361 ttttaattaa agaaaaggaa tacataggag ttgagacaag agattttttt agaaatattc
    27421 atgattcttc tataaaaagt ttattgttgt cattacatga aaatattaat ttgagcaaag
    27481 atgatatttt acttattgaa gagtggataa aaaatctaaa agaagaggag aaagacgtat
    27541 aagcaaacgt atttcttata gcatcaatat aaagtgtatg taagtgtatt tatgtaatat
    27601 attagtctac ttaagtaata tgacaaatga ttataagtgg attatgatac tataatgtga
    27661 atctaaataa attaaatata aattaatagt ggatattcta tttaattaaa tttaaaaagc
    27721 tacctttact tataagtata attaaggtag ctttttaaat agaggtagtg taattaaaga
    27781 gaatttttaa atataaattg tgaagcttta atatagatga taatatatat tttgcaaata
    27841 tgacacagtg ttttcgtatt taagatgata aaataaatag gaattaatga tgatattgaa
    27901 aaaataaaaa taaaggatta atataagata ttaaagagat agagataaaa gtgttaacag
    27961 aagatattga aaaaataaaa gattgatata agatactgaa gaggtagaaa caaaagtatt
    28021 aatagaagat attgaaaaaa taaaaacaaa agattgatag aaagtactga atagatagag
    28081 ataaaagtgt taatagaaga tattgaaaaa ataaaagatt gatataagat actgaagagg
    28141 tagaaacaaa agtgttaata gaagatattg aaaacataaa aacaaaagat tgatagaaag
    28201 tactgaatag atagagataa aagtgttaat agaagatatt gaaaaaataa aagattgata
    28261 taagatactg aataggtaga aacaaaagtg ttaatagaag atgctaaaaa agtaaaaata
    28321 aaggattaat aaaaggtact gaagagatag agaaaaaaat gttaatagaa gatactgaaa
    28381 aaatagaaat aaaaaattag gaggaaaatt tatgaaatat caggtttcat tattagcagt
    28441 gaaggatatt gaagtatcaa aaaaatttta taaagaatta tttgagcaag aaattgaatt
    28501 ggacttaggc aaaaatgtaa catttaaagg aggatttgct atacaagaag acttcgcatg
    28561 gcttacaggg attaatccag atacaattat acaaaaatca aataatatgg aactttattt
    28621 tgaggttgat gattttgacg aatttattga aaaactcaat tattataaag atgtagagtt
    28681 tgtccataag ccactaaaac atgaatggca acaaagagta gtgcgtattt atgacccgga
    28741 taagcatatt attgagatag gagagtctat ggaagttata gctagaagat atttatctga
    28801 gggatactct gtagaagaaa cttctaaaat aattcaacat ccaattaaat ttgtaaagca
    28861 gtgtgaaaat agtaaggaat gattgtttaa attataatta tttagtagaa attaattgta
    28921 atagaactaa ttcaagataa tatataggac tagtatttga caaa
//
LOCUS       DAMJWC010000050        28667 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMJWC010000050 DAMJWC010000000
VERSION     DAMJWC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28667
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.050"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(224..2503)
                     /locus_tag="PC503_002542"
     CDS             complement(224..2503)
                     /locus_tag="PC503_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2528508.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2774..4228)
                     /locus_tag="PC503_002543"
     CDS             complement(2774..4228)
                     /locus_tag="PC503_002543"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF2528509.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4392..5261
                     /locus_tag="PC503_002544"
     CDS             4392..5261
                     /locus_tag="PC503_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2528510.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5474..7546)
                     /locus_tag="PC503_002545"
     CDS             complement(5474..7546)
                     /locus_tag="PC503_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2528511.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGELLDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(7849..8691)
                     /locus_tag="PC503_002546"
     CDS             complement(7849..8691)
                     /locus_tag="PC503_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2528512.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(8952..10994)
                     /locus_tag="PC503_002547"
     CDS             complement(8952..10994)
                     /locus_tag="PC503_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDF2528513.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(11146..12117)
                     /locus_tag="PC503_002548"
     CDS             complement(11146..12117)
                     /locus_tag="PC503_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF2528514.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(12118..13095)
                     /locus_tag="PC503_002549"
     CDS             complement(12118..13095)
                     /locus_tag="PC503_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528515.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            13314..14873
                     /locus_tag="PC503_002550"
     CDS             13314..14873
                     /locus_tag="PC503_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2528516.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGESKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            14979..15938
                     /locus_tag="PC503_002551"
     CDS             14979..15938
                     /locus_tag="PC503_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528517.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPAYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLAKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            15941..16753
                     /locus_tag="PC503_002552"
     CDS             15941..16753
                     /locus_tag="PC503_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528518.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(16969..17871)
                     /locus_tag="PC503_002553"
     CDS             complement(16969..17871)
                     /locus_tag="PC503_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2528519.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            18226..19404
                     /locus_tag="PC503_002554"
     CDS             18226..19404
                     /locus_tag="PC503_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2528520.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            19413..20069
                     /locus_tag="PC503_002555"
     CDS             19413..20069
                     /locus_tag="PC503_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF2528521.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            20069..20734
                     /locus_tag="PC503_002556"
     CDS             20069..20734
                     /locus_tag="PC503_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF2528522.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            20839..21615
                     /locus_tag="PC503_002557"
     CDS             20839..21615
                     /locus_tag="PC503_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2528523.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            21677..23011
                     /locus_tag="PC503_002558"
     CDS             21677..23011
                     /locus_tag="PC503_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2528524.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            23507..24439
                     /locus_tag="PC503_002559"
     CDS             23507..24439
                     /locus_tag="PC503_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF2528525.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNNNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVAT
                     KKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSE
                     GHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(24831..28370)
                     /gene="nifJ"
                     /locus_tag="PC503_002560"
     CDS             complement(24831..28370)
                     /gene="nifJ"
                     /locus_tag="PC503_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF2528526.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPVNT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMGICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         9863 a         4563 c         3750 g        10491 t
ORIGIN      
        1 ttactatcta aagtattttg ctataatccc atatactctt acctcaaaaa cattcaaatg
       61 taaaaaatac tacatattaa taaactttgc ccaataattc ctaaaataat atcctaacaa
      121 tgatttatgt ttttataata gtatattttt acataaaaaa gtgaacattg attaacaaag
      181 ttcacttttt tataaatttt tatgttataa ttcacaattt tatttaattt gtttcttttc
      241 tatttaaact atatctatct aatattaatt tttcatattc ttctattggc attggtctag
      301 caaataaaaa tccttgggcc atatcacaac ctataaacct taaaaactct gcttgctcta
      361 cagtttcaac accttctgaa acaactttta tatcaagttg ctttgccatt tgaacaatac
      421 ttgaaactac aatttgactc ttttttgcat ttcccactgt tataaagaat tgcctatcta
      481 atttcaatac atcaattggc atatctttaa gcatatttaa agaagaataa ccagaaccaa
      541 aatcatccat agaaatttta aatccaacag atttcaaagt ttgcattatt ttaaataata
      601 tttttgtatt gtcaaatatt gcactttctg tcaattcaat ctcaattaaa tttggttcaa
      661 tttcatattc ttttgttatt ctttcaagct cagaaataaa gcctggattc tcaagatgta
      721 ctcttgataa gtttattgat ataggaaatg tggggaaatt ttcattttcc caacgtttaa
      781 aatttttaca aacttgggta aatacaaaca tatccaattc tgttataaaa ccatttttct
      841 caaaaatagg aataaataca cctggactta ttagaccttt tttgggatgt tgccaacgta
      901 caagtgcttc agcacctaca attttagtag ttgataaatc aaccttaggc tgtaaataaa
      961 ctttaaattg ttcatttttt aaagcatcat gcatttcttg ttcaatatca cgttcttcta
     1021 tgagagtttc ttttaaattt tcagcataaa tctcataaac ttttaaatat tttcttttta
     1081 ctgtagtttt tgcaatcata gctttgtcaa gacaggtaga aatatttgtt tctccctctt
     1141 caacaaaata tacacctatg gatggaatta aattgagttc tactcccaaa cttgttttta
     1201 tcattgacaa ttttttacgt ataagttcac atatttctat aattgactct ctattatttt
     1261 tcttttcaaa tattatagca aaattgtcat ttgaaattct tgaaaataca gattgctctt
     1321 taaatatatt cttaattatc tctgctattt cctttaatac tctatctcct tcttcatacc
     1381 caaacctatc atttactagc ttaaacttat ctatatcaaa ataaattaaa actagattct
     1441 ttttctcatg agaggataaa aattttcccc cttcaagatt aaatttattt gaattgccaa
     1501 tacctgtaac gttatcttta aaagcaaatt cttccaattt ttccttactc tttttatgta
     1561 taaatagtat ataaattgtt aatgccgtaa agattataat caagactaca catgctgata
     1621 atgtaagttt tataatagca tatgatttct cagatatagc agttttagga acttcagaaa
     1681 aaagatacca atcattgatt cctattgggg cataacttaa ataatatcct tttccaaaca
     1741 tactataact taatgaacct gatttaaagt tttttatatt tgacttcata ttgttgatac
     1801 tagattttga tattgaatca cttctgccaa tgtaagaaaa taaattttct ttagtagagt
     1861 tggcgttttt actgcttgga tttaaaacaa tatcaccatt acttctagtt atataagaat
     1921 atccttttcc attaaatgta ggtacagaaa gtattttttc atacaacttc gtactatgtg
     1981 tggcaaatat aactccttta acctcattat ctttataaat tggtacagaa tatacattaa
     2041 tattactatt ggtattttta tcatcttcta ttacatcttt taattttcct gttataacca
     2101 cttctccttg cattgatttt aagaaataat ctcttttaga gaagtcttct atataaccat
     2161 ctgtagtgta tgctgtacca tttggtaaaa taactcccat tcttttaaat gaactattaa
     2221 tagcttgtct ttttagtata gaaaggatat tatctacttc aaaagactct tctccttcaa
     2281 taaatattga aattgactct agtaacttta tatctccatt aatttgtttt tttaacacat
     2341 tgacgctttg atttgctatt tctgaaagat attgattcgt ttcttcacct aatgtcttat
     2401 tcaaccttga accataaatc aaacaggaaa ttgtaattac taagatactt atgacagcaa
     2461 ttatggacaa accataccta ttattttttg catcacttaa cattatgctt cctgcctttc
     2521 tcgaatctat gtatgtataa tcattatctt atgacaatta ttgtaaacat tttataataa
     2581 tacttatttt tccatattta ctgtaattat acaaaattat aaactttatt acaacaataa
     2641 attaattaat atagatatta gtgtttacat tattgcatta tctattttac aattatttac
     2701 atataaaaaa atgtaatatc aaagtgaagc ttgatattac atttttgttc ttgtattttg
     2761 tttaattttt atgctacatc ttacttaaac actcatttgc aacttcttta tcatcaaaat
     2821 gatgcttaac tttacctata atttgataag tttcatgtcc cttacctgtt ataattacaa
     2881 catcatcctt ttttgccata cttatagctt ctgctatagc ttgttctcta tcaacaacaa
     2941 catggtaatt ttcttttttc ttgtcaattc cttcaagtat atcttttatt attgcctctg
     3001 gttcttcagt tcttggatta tcagaagtta taatacataa atcagaatat ttttgtccaa
     3061 ttgctcccat caaaggtctc ttttcagtat ctctatctcc accacaccca aacacagaaa
     3121 ttatttttcc ttctgcaaat tgttgagttg tctttagtac attttcaagt gcgtcaggag
     3181 tatgagcata gtctacaatt acgcttatac ctttatcatt tggaactgtt tcaaaccttc
     3241 ctgatactcc attagaaagt ctaaggcctt ctttatatat tggtttaggt atgccaagta
     3301 catagcaagc agctataact gctaaagtat tatatactgt aaacatccct ggaactggta
     3361 taaatattac ttcttcatat gaaggtgtta ttaatctata agatactcca tccgaatctg
     3421 attttatatc tctagccata aaatcagcct tagtatcaac accataagtg taacaaggta
     3481 catttatacc ttttatattt tcatatatct tttttccacc ttcatcatct atgtttatta
     3541 tatttgccat agtagtctta aaaaataatt tttcttttgc ttttctataa tcctctaaat
     3601 ctttatgaaa atctaaatgg tctggtgtta aatttgtaaa tatgcctagt ttaaagtctg
     3661 tttcatcaac tctatttaat gccaatgaat gtgatgaaac ttccattgca cagtagtcac
     3721 atccattatc caacatatta ttaaaatgat attgtaaatc tatactttct ggagttgttg
     3781 aattggaaac aatgtctttt tctccatcaa aaatttttat agttcctata agtccaactt
     3841 tattcttatt taaagttaat atctcattta gtatagtagt tatactagtt tttccattag
     3901 tacctgtaac tcctataacg ttaaattttt gagatggatg attgtaaaaa ttatcagcta
     3961 cttttgccat atcttttctt gtatctttta cctttataaa tgtacatcct tttattgcta
     4021 catcttcttc aacaagaaat gcacttgctc ccttttctat ggcatctttt atatacttat
     4081 gaccatctga cacaaatcct tttatacata taaataatgt accttttgta acctttcttg
     4141 aatcatattg tacattatta atatctatat ttaattcacc cttgacattg attatatcca
     4201 acccctgtat aatatcattt aatttcataa atgctttcct ccctttaaac tctttctgct
     4261 aaaattacac tacatataat attatattaa gaatttttta ctatgtgaat ggttaaaaat
     4321 gcttgaaaca ttgcaaaaaa tgctctataa ttttctataa tataactgag gaaaggtctt
     4381 ctataaaaac tatggataat aaaatcgggt acttaaacga taactttaaa atatttaata
     4441 ttagagataa aaaagatata caatttgaat accataatca tgattttaat aagataatta
     4501 tatttataaa tggaaatgta acttattttg ttgatggtat tccctataaa ctaaagcctt
     4561 gggatatact ctttatcagc aataatgaaa tccataaacc agttatagat tcaaatgtct
     4621 tttatgagag aattgcaata tggattagcc cagaatttat gaaaaaaaat agtgatgcta
     4681 gtagtgactt agaaaaatgt tttaaaatag ctacagagaa taaatgcaat agattgcgtt
     4741 taaatatgca tgatattgaa tctattaaga gttttattga gcaaataaat atttccgaat
     4801 ccaatactga atttggaaat gaaatattga gaaatacatt atttatacaa cttatgatat
     4861 tcttaaacag aattttccta aaaaatgaaa atatggaatc aacagaagat gttttttatg
     4921 atgaaactat taagaaagta ttaaactata taaattcaaa tatagatgat aagctttcaa
     4981 tagatagcat atcgtctgaa ttttttataa gtaagtatta tcttatgaga aaatttaaat
     5041 ctcatactgg aacgtctata cacaattata tagttcaaaa aagattaatt ttggcaaagt
     5101 cactaataac caatggtcac cttatgagtg aagtttgtaa taaatgtgga ttcaacgatt
     5161 attctagttt tgtaagggca tttaaaaaaa actacggtgt atctcctaaa aattatataa
     5221 acaataaaaa tcctttagat attactcttt tagatgaata gataatttat gtaaatttta
     5281 ttttaataaa acttgaagta ttagtgtatt tatcttacta atacctcaag ttttttaatg
     5341 ttttaaaata tatcaaaata taatgatata tatttctatt acttaaaata tatattaaat
     5401 aaattgcatg ttaactgaac ctatttatat atttattaaa tctcacataa cttttagtta
     5461 cactatcata tagctatcct attttttcaa tatcatctct taatatactt actctattct
     5521 cctcttttgc tgtggttact ccttttttaa tgcttaattt ctgattttgt tctaaattcg
     5581 taaatactac aggacttatt gttgatagac catttttttc aatatattct aagtccattt
     5641 taactaattt ttctcccgct tttacttcat ctcctacatt cacaaatact tcaaatccat
     5701 ttccttctaa gtttacagtt tctatcccta aatgtataag tatttctact ccactttttt
     5761 gggattttat tattattgca tgcttagttg gaaatataac tccaatagtt ccatcaactg
     5821 gtgaataaat caatccatca ctagatttaa ttgcaaatcc atcccccatc agtttacttg
     5881 aaaatacaga atctggcact tcttctatat ctaataactc tccatttgtt aatgaatcaa
     5941 tcttttctac taaagtattt tccatatttg caacttccat attttttttc actttatttt
     6001 tatcaacatt tttagtaaca gtactttcaa cctttgtttt tccctctatt atatctttta
     6061 tatcagactt tattgaatct gattttggtc caaatatagc ttgaacattg ttgccaataa
     6121 ccataacacc tgctgctcca agtgatttca atttttcttt atctacttta tttatatcat
     6181 ttacaaccaa tctaagtctt gttatacacg catctagact ctttaagttg tctttatttc
     6241 ctaaagcaat caaaatctct gatgctaatt cattcttaga catttcaatg acttcagcgt
     6301 tagtttctga ctcatcttct cttcctggtg tctttaaatt aaattttctt atcataaatc
     6361 taaatacact atagtataat actgcaaaac caatacctac caagatagcc aagtaccatg
     6421 gagttctatt aggaagaaca ccaaataata agaaatctat taatcctcct gaaaatgtga
     6481 atccaatttt aactcctaat aattgcataa ttgcgtatga taaacctgaa aataaacaat
     6541 gtattgcaaa taatactggt gcaacaaata aaaacgcaaa ctctattggc tcggttattc
     6601 ctgttaaaaa agaggttaat gctgctgatg ccattatacc tgctacaaat tttttctttt
     6661 ctggctttgc ttcatgcacc atagcaagag ctgctgctgg aagaccaaac atcataaatg
     6721 gaaatgcacc tgtcataaaa gtacctgctg tgaaatttac tccatcttta agttgagcaa
     6781 agaatatctt ttggtcaccc attacaagct caccagcttt atttacatat tctccaaatt
     6841 gataccaaaa tggattatgg aaaacatgat gcaaaccaaa tggtattaat agtctttcca
     6901 aagaaccttc cataaatgct gctagtgttt gatttgcttc tataacattt tttgagaaac
     6961 taagtaatcc ctcttgtatt ggaggccaaa taaaagacaa tataattcct attgctatag
     7021 caactaatga agtaacgatt ggtacaaatc ttttacctgc aaaaaaacct agatactgag
     7081 gtaattcaat tttataaaac tttttataaa gataagcagc cactatccct ataataatac
     7141 caccaaatac ccctgtttga attgttggta ttccaacaat atttgcatac atagaattgt
     7201 ctaccatatc ttctgtaaca cctgccataa cacccataga tgtattgaga attaaaaaac
     7261 ctactatggc tgccaatgct gcaacacctt ctccttcagt taaaccaaca gctaccccaa
     7321 ctgcaaatat aagtggtaag ttattaaata taatttgacc tgaactttcc attatactta
     7381 ttataagttg aaatgtagga ttcgccaaag ctggaaaatg agccaacaat gcgtctcctg
     7441 ctaaagcatt actcacgcca agtaatatac ctgctgcagg aagtaatgca actggtagca
     7501 ttagagattt tcctactttt tgtaaaacac caaatacttt tttcatttac ttttctctcc
     7561 ttattatttt atattttttt aaataaaaaa gacttaagtt tataaaaagt tacattagta
     7621 tacttaattc taaaattaaa cttatgttaa tataaacaaa cctatattaa cctaatttca
     7681 gaattaaaaa taaactatta taattttttt ataaacataa gtcttgcctg cattatcagt
     7741 aacaatctta atgttttaaa attattattt tatattaaat tttaaataat atattaaaat
     7801 taaacataat atattaaatc tatacattct gtattaaact actctttatt ataaattcag
     7861 tacagatata actcttttga tatgtaatgt taaataaagt agttcatctt gacttacata
     7921 gtaatcataa ttcttttcta catgagtttt tattttatat gcacaatcat aatccttttc
     7981 atactttact ttaattatat ctataatttc attatttgta tcattgattt tttctttttt
     8041 tactaatcgt tttgcaaaga attttaaatg agtcagaagc ctatcataat ttatatcatc
     8101 ttctttaaat tcaactctat aataatatct tataatattt agtatgtctt ttacaatttt
     8161 agtaattaac agtgattcct ttgaacttcc cttatagttt gaatttacta tatgcattgc
     8221 tataaaacca gcttcatcta ctggaaattt cacatcaaat tctttattta tataatctac
     8281 agcccatttc ccaatctcat attctttttt atgtattctt tttatctcat gtagtaaatc
     8341 attctttata gttatgtttt catgatatct tttaattgca aatgcaatat ggtcagtaag
     8401 tgctacataa atatattcat aaagtttagt attcaaattc tcctctgcat aagcaattat
     8461 ttcagtacta acctcaaaaa atttctcatc aacctggctt gctagtttac taattttatc
     8521 taaaaagctt tcatcttgta ttacaaaagt tctttcaatt ttacttttat ctatttcttg
     8581 acctttcttt ttttgaaacc caattccaca tcctgttaat attaattctt tttttatatt
     8641 ttcatctaaa actaatacaa cattattatt ataaatttgt tgaataatca taatcaatat
     8701 ctctcccaaa atacaatttc ccttattcat aaaaaaatac ctaaattaag atacaattca
     8761 cctgtatacc ttaacctagg tattgcctgc ttaccagtaa caatccagct tgttaacgct
     8821 tatatattgt attcaattta tggttttatt ctattataaa taaatatata tgtcaagtaa
     8881 attattgaaa actatttcct attttttagt attaatttta acatcaaaaa tcaaatttta
     8941 ttccattata tttatgattc tatcatcatc atttcatcat agagaatatt ttccaataac
     9001 tctttagcca cttctcttga tatttgctta gtttcaacta attgttgaac actgtctctt
     9061 tgactttgta tcgccattac tctgtagtat tctactcttg cctcaaactt atcatcattt
     9121 tgaatctttc tagtaatcca attcaaataa cgattataga atctgattgc tattaaggcc
     9181 tcatgtctgt tatcttcatc agtattttta tttataaatg atatagcagt tttagtagaa
     9241 agtgcatatg catggtgaaa ctctttgatt atttctttat tctcagatac tatttttgta
     9301 attttttctt ttacttcttt ctttactttt ctatttataa tccacatgct tatttttaat
     9361 tttacaattt taaatataga tttttgaaca gattttcttg attttgtaat ataaaatcta
     9421 tacaatttaa aggctctatc agaaatttta ccatcttcta atagtttcaa aacagctaat
     9481 aatccctgtt ggtctgcttc tgcaatcatc atacttataa gtttattatc tggagtattt
     9541 agtattcctt tttctgagtc taccaactgt tcatttaaat catgtataac tggttgtact
     9601 tcttgtgctt tttcattact aagttttaaa atggcttctt tcaaaattag tttatatgcc
     9661 tctttatcag ataataaagg ttctgactct tgtacgttat tttttaataa tcttggcagt
     9721 aaaactgttg ccaatactaa acttataaga ataacttctg atgatataaa taaaacagta
     9781 tctctcattg gaaatacatc tttatcagcc aaataaaaag gtatagataa ggcagttgct
     9841 agtgtaaatg taccatgaac accacaagta gcaactatta gtgagtattt acatttagaa
     9901 atactctctt ttacaacttc ttcatcctta aaacctaaaa aacctacaaa aaaattattt
     9961 aaaggattct ttttaggttt tataaaagaa ttatgccata aatataccca tataaatctt
    10021 ataacaaata aaataagtac aattaaagta gaaataaaag tcaattccaa tgccatattt
    10081 tcatttttac tactaagtcc tgtatatata cttggtaaca aaaaaccaag cagtgtaaag
    10141 acaaatccat tcaatacata ctccaaaaca taccaagtat tgtctgatat tatccttaat
    10201 ttagtagttg tattttgtaa atgctctttt tcaattccat gagctatccc tgccattaca
    10261 acagctagga ttccagatac tcctatttct tctgctacaa aatatacaaa aagtggagtc
    10321 attatttgta taactattac cattggaatt tcttccaaat tccacttgtg taaactaagt
    10381 cttattttta taattatgta tcctaaaata cttcctacta ttattcctcc aaaagctgta
    10441 atcataaatt gaatccctgc ctcttctatt gaaaaaactc ctgtaactgt ggcaagtact
    10501 gcaaccttaa atgctactac tccagcagca tcatttaata aagattcacc ttcaagtata
    10561 ctcatcatat ttttaggaaa atttaatcct tgtgtaattg attttactgc tactaaatca
    10621 gttggagata ttactgctgc caaagcaaat gaaacagata atggcatccc aggaataaga
    10681 aaatgtataa agattccacc tgcaaacacg gttattaaaa ctaaaccaaa tgcaagaagc
    10741 aaaattggtt ttctgagctc taatagctct tttctcgata cattttgtcc ttcactgaat
    10801 agtaatggag ctatgataca tattacaaat atttctggat taaatgaaaa tgagaattta
    10861 aatggcaaaa tagacaatat aatccctagt acaatttgat atattgcaag aggaatatta
    10921 ctccactttt tgctaaatac agttgaaatc gttgtacaaa ccaataatcc caacaatgtt
    10981 actaaaattg acataactac ctctcttttc aataataata ttatagatta aacttatata
    11041 tcaactaact taatattaac agcatgaaat cccatcttaa tcaaaaaaat tttcagttta
    11101 ttctattatt cttattatat acatcaaatt taatttttga aatatctata ctagatgaca
    11161 tgcaacaaaa tgatttcttg atatttcttt taaaactgga atctcttttt tgcatatttc
    11221 cttacaataa gggcatcttg tatgaaactt acatccactt ggtggatttg ttggagatgg
    11281 tatgtctcct tttaatataa ttctattttt cttaattgta gggtcttgta ttggtactgc
    11341 gctcataagc gcttttgtat atggatgttg agaatgtaag taaagttctc ctttagttgc
    11401 aatttctatt atagaaccta gatacataac acaaactcta tgtgcaatat gatttactac
    11461 actcaaatca tgagatataa ataaatatga aagtttatat ttatcctgta aatccataag
    11521 taaatttata atttgagatt gaatagaaac atctagtgca gaaacaggtt catcacaaac
    11581 tataaattct ggatttaatg ctaatgctct tgctatacct attctctgtc tttgacctcc
    11641 agaaaactca cctggttttc tatttaaatg gtacttagaa agaccacaac tttctacaac
    11701 atttaatata ttatctttta tttcattctt tggcactaaa ttatgttcta taactgcctc
    11761 ggatattatt tgttccacat ttaatcttgg atttaatgaa ctatatgggt cttgaaatat
    11821 catttgcatt ttgggtctta actttctaag ttcttccttc tctaacttat atatatctac
    11881 accattaaat tcaactttac cttcagtttt ttcaattaat ctaagaatgg ttcttcctgc
    11941 agttgatttt ccacatcccg attctccaac tatagccaaa gtttctcctt tttttaaatc
    12001 aaaagaaatt ccatctactg cctttacaca tttaatttcc ttatcaaata atccagattt
    12061 aacttcaaag tactttttaa gaccttctac ttttaataaa ctctcttctt ttttcaatta
    12121 tatctcctcc tttttatata accaacatgc aatactatga ccactattca attctattaa
    12181 aggaggtatc tgagttctac atttatcaca tactttttca catctatcac taaaataaca
    12241 tgaatctggc atcccaattg gatttggtac ttgtcctgga atcgaataca atcttttatc
    12301 tttgtttttt ccaagagcag gctttgattt tagaagtcca atagtataag gatgttttgg
    12361 atttttaaat aattcaacaa cctctgccac ttctataatt ttgccagcat acatcactaa
    12421 tactttgtca cacatttctg caactactcc caaatcatgt gtaatcatca ttatagatgt
    12481 gtttaatttt tcttttatat ttttcattat atctaaaatc tgagcttgaa tagtaacatc
    12541 taaagctgtt gttggttcat cagctataag taattttgga ttacatgata aagccatagc
    12601 tatcattatt cgttgtctca ttccacctga taattcatgt ggatatgaat tatatatttc
    12661 ttcagctctt ggtatttcta ccagttttat catatcgatt acctttttct tagcttcttc
    12721 ctttgataaa tcttgatgta tcataatacc ttcaatgatt tgacttccaa tagtaaacgc
    12781 tgggtttaaa gatgtcattg gttcttgaaa aatcattgat atctcattcc ctcttattcc
    12841 cataagttca tcttcattca tctttaaaat atctttgcct cgaaagatta tttctccacc
    12901 ttctattttt gatgttggaa gtaacttcat caaagacatg gctgttacag acttaccaca
    12961 tcctgattct ccaactattc caatagtttc accttcattt atattaaaac ttacttcatt
    13021 tacactcttt acaatccctt tatctgtatg aaaataaact tttaaatctt taacctcaat
    13081 tagtgcttta ctcattattt tctcctctca gcaaaattac ttaagataac atacaccttt
    13141 tgattgtatt ttataaaaat ttaaattaca acattttctt acattttatt atttttttct
    13201 attaattata ataatataat agttaatttc tatatatatt gatttaataa tgattactat
    13261 tatacaataa aaaatatgtg ttaaatatta ttttatggag gttttataag aatatgaaat
    13321 ttaaaaaatt ggcatcatta atcttagttt catcattaat gcttacattt acagcctgtg
    13381 cttccaatga taaagacaag tctagtggaa gcaaatctgg tggaactgtt gtaataccta
    13441 tggcaagtga cccagatata atcaatggag cttttgcaaa cgttaaagaa gactctcttg
    13501 catcaaatat agtttatgct cctctttata cttatgaaaa aggaaattta gtaaattatt
    13561 tagcagaaaa agtagatttt aaagatagta aggaattaac tataaaatta aaatccaatt
    13621 taaaatggca tgatggaaag ccaataactg ctgaagatgt cttatttaca tttaatacag
    13681 ttttagacga aaaacaaaat tcaccatcaa gacaatactt attggtgggt gagaaaccag
    13741 ttaaagtaga aaaaattgat gatttaacag ttaagattac tttaccaact gcaagtgaat
    13801 ctttcttata tggtatatct aaaatttctc caataccaaa acatgtgttt gaaggagaat
    13861 caaatatagc taagtcagaa aaaaataata atccagttgg ttctggtgca ttcaagttta
    13921 aggaatggaa aaaaggtgaa agcatagtat ttgaaaagaa tgcagattat tttggtggag
    13981 aatctaaggc agattctata gcgctaaaaa taattcctaa tgaagcatct caagaagcag
    14041 ctttaaataa tggcgaaatt tcacttatga agacatctgc tgaaggatat gaaaaggcaa
    14101 aatcaaactc aaatttacaa acttatactt atagtgaaga aagattaaac tacattgtat
    14161 ttaaccaaaa tatatcaaac atggctaaca aagaagtaag acaagcctta tcatatgcct
    14221 taaatagaaa tgaaatgata gaatcagcat atggaaaaga aggttctgta cctgctaaat
    14281 ctatattagt tccagaagca gacttctata cagaagaagg tgttgaagga tatgaccaag
    14341 atacaaataa ggctaaagac ttattggata aaagtggtgt taaaattgat aaattaaaaa
    14401 taggttataa cacaggtaga tttgggcata aaaactatgc cttagtagct caacaagagt
    14461 tgaaaaaaat tggtatagaa gctgaaatag ttccttatga aagtaaggca ttcttcaata
    14521 tactatttag taatagcact gaatgtgata tgtatgtaaa tggttatgct tggggattag
    14581 aaccaaaccc atatagaggt atgtttgaaa ctggtcaata ttgcaaccaa actaaatatt
    14641 ctaatgctga aatagatgct ttatgggaaa aaggatttac tgagttaaac aaggaaaaac
    14701 gtgaagaaat atataagcaa atacaacagg atatatctaa ggatgcgcct atttacacta
    14761 tagattatga acaaaattta atggcagctc aaaaaaatct aaaaggaata aaagatgcta
    14821 aaccatctcc tgcaatatta tttgaagatt ggtctaaact gtatgtagaa taattgatgt
    14881 aaaattttat attattaatt agaaaaggag atgtctaaaa ataatattgt tttattattt
    14941 taaaacgaga catctctttt aattaggaga atttacttat gttaaaatta atattgaata
    15001 gagtaaaagt tttaatacct atgttaatct taatatctat attatcattt ggacttttag
    15061 aattagctcc tggtgaccca gcagatgcat atataaatcc tttaatgtct tcacaggata
    15121 ttgaaaatat aagggttaat atggggcttg ataaaccagc atatataaga tatttaaact
    15181 ggttgaaaaa cactttaagt ggaaacttag gtatttctta tataaaccat atgcccgtta
    15241 cagaacaaat tatggaaaaa atgggaaata catttattct tatgggtact tctttgatat
    15301 tttcaatatt ggtagccata cctcttggaa tatttttagc tgtaaataaa aattcaataa
    15361 ctagtaaagt atcatctgtt tttaattata taggtgtttc tataccttct ttttggatag
    15421 gtatgatact catttcaatt ttttcagtta aacttaacat tttcccatca ggaggtatgc
    15481 atactattgg aaatgatagt attggagatt tagcaaaaca tttagttttg cctgtaataa
    15541 ctttaggtct atataatact gctattttta caaattatgt agaagctagt gtaaatgaac
    15601 aattaaaaaa acaatatgtt attacagcaa gagcaaaagg attatcagaa aaagtcatac
    15661 tatttaaaca tgtcttgaaa aattcactga catcattggt tacaatccta ggcatgagta
    15721 tacaaaaatt agtcactggt gcatttgtta cagaagtagt tttctcttgg ccaggtatgg
    15781 gaagattaat gattgattca attttttcaa gagattatac tgtaattatg gcaataacta
    15841 tgttatcagc actattttta attttaggta atttagttgc tgatatacta tacttattaa
    15901 ttgaccctaa aataaaatct agcaaaggag gattctagtt gtgtttacaa gtatcttaaa
    15961 aaaattaaaa aaagataaat cctttgcttt tgcatgtatt actcttagca taataatcat
    16021 attaattata gcttctttta tattaaatat agactctaat gcaattgata ctacttctaa
    16081 acttcaagaa cctagcttaa agcatatctt tggtacagac gaacttggta gagattactt
    16141 ctctagagct ctttatggtg gaaggatttc acttagtgtt ggtattttat caatgcttat
    16201 ttctgtagta tttggtactg ctgtaggtgt tattagtgga tatattggag gtaagctaga
    16261 ccaattcttg atgagattag tggatatgct tatgagtata ccaagtttct tagttttgat
    16321 tgtattaaat acttatctaa cacctaaagt ttccactatt atactaatta ttggattctt
    16381 aagttggatg gaagtttcaa gaattgtacg tggcgaaaca ttaaaaataa aggaaaatga
    16441 atactgtcta gctgctaaag ctactggtat caaaactaga aatatactat taagacatat
    16501 agttttaaac ttaaaagaga ctattgtagt tgctggttcg ttaaatattg ctaatgctat
    16561 cttaactgaa tctgctctta gttttttagg tcttggaatc caattgcctc ttgcatcatg
    16621 gggtaatatg cttcaagatg ctcaaagaca tatttttgac aagttatatt tagctgtatt
    16681 tccaggatta cttatatttt taacagtcat gagtttgact ataataagca aaaaattttc
    16741 tagtaatact taacaaattt tatatagaaa ataaaaacag tgattatcta aagatataca
    16801 ctgtttttat ttttcgttta aaaaaataca tattttgtat attataactt taaatactac
    16861 tctaccatgt tatgcaaagc gtattattgc tctcaaacat atagatgaaa aactaatagt
    16921 ttattataat aaaaattgat ttatttattt gttattttaa taacattttt aagagttctt
    16981 tttactaaag aaatctataa taaatttaaa tacatgttgg tctacatggc tataacgttc
    17041 ttttttaggt ctacataata taactttcca tgtaatagga tgattaaaag gcttttctat
    17101 aattttgcta ttttcaaaaa aatcatgaac tggtgatggt aaaattgtta taaaatcaga
    17161 atttgtggtt gatagcaaca aaaaatccca tgaaccagac attatatatc tttttaactt
    17221 aacattttca tcagtaaatt tttgcattag cttatgatgt atcataaaag taggattaaa
    17281 tattgcaagt aactgctcat tcaaatcgtt ccaatctatc ttatccttct tagcaagtgg
    17341 atgatttata tttaaaaatg ctgtaagttc atcttcttga agcacatgtt cagttactac
    17401 acttttatca attttatgtg gatgtaacaa tactgcataa tctaattcct gtaagataag
    17461 cattctattt aagtcatatg cacccttctc tactatatca aattctatat ctggattatt
    17521 tgcaactaac tgtgcaacta catctgaaaa tgctattcca agtataagtg gaggtattcc
    17581 tattctaact tttcctttaa attgaactga atcttctctt aaatcttcca tcatattttt
    17641 gtattcattt atgatatgtt ctgcatttac ataaaatctt tctcctgctg gtgttaaccc
    17701 atttaacctg cctttatacc tttcaaataa atatacatct tcactttctt caaaattttt
    17761 tataatttga cttaatgctg gttgagatat gtgaagtgtc ttagatgcta ttgataaatt
    17821 aaaaccagat ttcactattt caacaaaata tttcaactgt tttatatcca ttttaaaccc
    17881 ccttccccaa aagtataatt tagattatat tttttcttct aatgatattt tataggaaaa
    17941 tcaacataat ttcattaata ttttaacaaa atatttttct aaatctacta taaattttta
    18001 tcctataaat ttttcttata cactatataa aaaattagac ttagacaaaa cgcttttttc
    18061 gccgtaatct ataattagaa acaggaaaac ctaaagcatt aggaataaaa gtaattgaaa
    18121 tacttaaaaa caagcttgta ttaaaaaagt actttattat agtgttccct aatttcttta
    18181 ttcagaaaat ttttaattat cattcaagaa aggtaactat tagatatgaa agatgtagta
    18241 atcgtatcag cagtcagaac acctatagga agttttggag gtgtatttaa aaatacttca
    18301 gctgttcaac ttggaactat cgctgttaaa gaagcgatat cacgtgtaag acttaattta
    18361 tctgaaatag atgaagtaat aattggaaat gttcttcaaa cagggcttgg acagaatgtt
    18421 gctagacaaa ttgctataaa tgcaggtata ccaaattctg ttccaagcta cacagtaaat
    18481 aaattatgtg gttcagggct taaaagtgtc cagctagctg cccaatcaat cacatctggt
    18541 gaaaatgatg tggtaattgc aggtggtact gaaaatatga gccaagctcc ttatatcgtt
    18601 ccaactgctc gctttggtag taaaatgggt gacataacca tggtagatag tatgctaaca
    18661 gatggcctta ttgatgcttt caatcagtat catatgggaa taactgcaga aaatattgca
    18721 actaaatttg aatttactag agaaatgcaa gataaattgg cattagaaag tcaaaataag
    18781 gctgagaatg ctataaaaaa caaccgcttt aaagaagaaa tcgttccagt agatgtttta
    18841 atacgtcgag gaaaaataga aactattgat aaagatgaat atcctaaatt aggtatgaca
    18901 tttgaaggtt tatctaaact taaacctgca ttcaaaaaag atggtactgt aacagctgga
    18961 aatgcctcag gtattaatga tggtgcggct atgttaatac taatgagcca acaaaaagca
    19021 gacgaactag gtattagacc acttgctaaa ataaaatcct atgcttcagc tggtgttgaa
    19081 cctgaagtca tgggtactgg tccaatccct gcaactagaa aagcactgaa aaaagctgga
    19141 cttagcatca atgatataga cttaatagaa gcaaatgaag cgtttgctgc ccaagcatta
    19201 gctgttaaaa atgaacttca aatagattca tcaaagttaa atgttaatgg tggtgcaata
    19261 gcattaggac atccaatagg agcaagtgga gctagaatac ttgttacctt aatttatgaa
    19321 atgcaaaaac gtaaagttga aactggactt gcaacacttt gtattggtgg tggtcaagga
    19381 atatcaatgg tggtttcacg ataggaggaa atatgaataa aatagttagc attgatgaag
    19441 ctctatctca tgtaaaagat ggagatacaa taatggttgg tggattcatg gccaatggtt
    19501 caccagaaaa tttaattgat tatttatgta gtaaaaatat aaaagatttg acactaattt
    19561 gcaatgatac tggctttatt gacaaaggag ttggcaaaat ggttgtaaat aagcaattta
    19621 aaaagataat tgcttctcat gtaggattaa ataaagaaac tggaagacaa atgaataaca
    19681 atgaaacaga tgttgagtta gttcctcagg gaactcttgc tgaacaaata cgtgcagctg
    19741 gttatggtct aggaggtata ctcacaccga ctggtattgg tactcttgtt gaggagggaa
    19801 agcaaaaaat tgttgtcgat agcaaagaat accttcttga aaaaccaatt tatgcagatg
    19861 ttgctcttct atttgcatca aaggtcgata aagcaggtaa tctagtttat aaaggctcta
    19921 tgaacaattt taataattta atggcatctg ctgccaaaat tacaatagtt gaagcagatg
    19981 aaatcgttga aattggtgat attgacccaa atgaagttaa tacaccaggt atttttgtga
    20041 attacatcgt tgaaggaggt aatttataat ggataaatta gaaatgcaag aatatattgc
    20101 aaatagagta tctaaagaat taaaagacgg agccgttgta aaccttggaa taggtctacc
    20161 aaccaaagta gcaaattata ttccggataa tgtaaacgtt atcttacaat ctgaaaatgg
    20221 ctttttaggt ttaggttcag ccgaagatgg aaattcaagt gatgaaacta ttgtaaatgc
    20281 aggtggtcaa ccagttacta tacttcctgg aggatgtttc tttgatagtg ctacttcttt
    20341 tggaataatc agaggaggtc atgttgatat aactgttctt ggcgcacttc aggttgacaa
    20401 atatggcaat atagcaaact atatgattcc aggtaagatg gttccaggta tgggtggagc
    20461 tatggaccta gtaactggag ctaaaaaagt tattgtagca atggaacata cttcaaaagg
    20521 ttctgcaaaa atattaaata attgtactct tccacttact gcaacaaatg ctgtagattt
    20581 gatagttact gaaatgggag ttatggaagt aacatcagat ggaattttac ttaaagaaat
    20641 aaatccagct ttcacattag atgatgttat ttctgctact gaagctcctt taatattgtc
    20701 agattcatta aatggaaaaa tatctgttgt ttaaaataat taaaactaga aaataaaaat
    20761 ctcttagacg tattacatat aaatttgtat tgcttaaaat attaatataa aaataaaata
    20821 aaattggagg aaatgaaaat ggttaaagat aaagttgtat tcgtaacagg agctgcaagt
    20881 ggaataggta aacaaatagc tgaatcgttc ttaaaaaatg gtgctaaagt aatgttctct
    20941 gatataaatc aagaagcttt aaataatacc ataacagagt tacaaaaaaa aggttatgat
    21001 tgcatgagtg taaagtgtga tgtaactaag gaagaagaaa ttaaccacgc tatagacaaa
    21061 actgttgaaa agtatggcag attagatata ttaataaaca atgctggact tcaacatgtt
    21121 tctatgatag aagatttccc aactgataaa tttgaattta tgataaaaat aatgctgaca
    21181 gcacctttta tagctactaa aaaagcattt cctataatga aaaaacaagg ctttggtcgt
    21241 ataataaata tggcctcaat caatggtgta ataggatttg ctggaaaggc tgcttataac
    21301 tcagcaaaac atggacttat tggactaaca aaagttgctg ctcttgaagc tgccgattct
    21361 ggtataacag ttaatgcttt atgccctgga tatgtagata ctccacttgt cagaggtcag
    21421 ttcaatgacc tttcaaaaac tcgtaatata ccattggaaa atgtcttaga ggaagtttta
    21481 tacccacttg taccacaaaa acgcctatta gatgttcaag aaattgccga ctatgctatg
    21541 ttcttagcaa gtgataatgc taagggtatt acaggacaag cttgcttact agatggagga
    21601 tatactgcac aatagttatt atatttaggg cttgaagaaa gtattcttca ggtccttcta
    21661 ctaaggaggg atatttatga gtattatcgc gccaattggt ataattattg gtatcatagc
    21721 tattatatat ttttcagtta aagaaattca tataactata gctgctccaa tagcaacttt
    21781 aatagttgtt attttaaata aaatggatgt tgtaacgtca atgctaggtg ctgacaaaaa
    21841 caattatatg ggtgcacttg gaaactatat aatgagttat tttgcaatat tcttattagg
    21901 ctcaatactt gctaaattta tggaagaaag tggagctact gtatcaatag ctgattttat
    21961 tttaaataaa tttggctcta atcatcctta tagagtttta gttgctatat ttatagtaag
    22021 ttttatatta acgtatggtg gtataagctt atttgtagtt atgtttgcgg tcattccact
    22081 tgcaagaact ctatttaaaa aacttgatat ttcttggaac cttattcaga taccactttg
    22141 gcttggtatt gcaacaatta ctatgactat aattcctgga acaccagcca ttcaaaatgt
    22201 tatacctatt caatatctaa atacgtctct tactgcagct actataccaa gtattgtagg
    22261 tagtataggt tgtgctacat ttggacttgt ctatatgaaa tatgctctaa acaaaagtat
    22321 tagaaaaggt gaaacttatg caacttacac ttcagaatta gaagaagaat ctttagatag
    22381 agaattacca ggattttttg caagtatttt tcctctatta gcactcgtaa ttatagctat
    22441 aactggaagt acttttggtt cagaatttat gaaaaaaaat gtaatttaca tagctttaat
    22501 agttgcaatt cttttatctg cttttttatt ccataaattt ctatcatcta agatacagac
    22561 attgagcata ggtgctagtg gttctatagg tcctatattt gctacatctt ctgcagttgc
    22621 atttggagca gtaataatgg ctgcacctgg ttttgatgta tttagcaaac ttataatgtc
    22681 aataccaggt agtccactta taagtcttac tgttttgact tcaacaatgt cagcaataac
    22741 agggtcctct tctggtgcat taggaatagt aatgccaaac tttgcagatt attatttaag
    22801 tactggtcta aatccagaat taattcaccg tgttgctaca atagcttcaa atatactaac
    22861 tatagttcca caaagtggtg tttttcttac attcttaagc ttatctaagt taacacataa
    22921 aactggattt aaagaaactt tcattgtagt tgcagttggt tcactaatag cagaaattat
    22981 tgtaattaca ttaggattac taatgtatta atataaaaca agttaaaatt cataatatga
    23041 aaggtggtgt ctcaaagtga actttttact taatgagaca ctctttttat atgaaataac
    23101 atatgcctat catttaaaca ataaaaaagg ccttatctct attttgagac agaccctttt
    23161 tatttcttaa agatttaaat aattataatt tgttgctaat acgaaagcat ctactgaata
    23221 aatttaacca aataaaaaaa aatttatcat aactataaat ttacgttatg gaattattat
    23281 aaaaatatta ttttctctaa ctaagtaatt ccatactata caggctttta atacaaattg
    23341 tcaaacacac tgaaatatac ctatttattc catatatatc ttttttacat atctttacag
    23401 taaaaaaagt cttaatctta tgttagtata gattcacggg taacccccta cactaaaggt
    23461 tacaaatcag taacattttt agaattttta gattaagagg tgtttaatga tgagaagaaa
    23521 tataccaaca aaattaaaaa ctatattagc tttaggagtg ttaactttag caacagcttc
    23581 aagtgctgtt actgcaagtg cttcatcact tgaaaataat gtaaatataa gtaacaaaag
    23641 tttagtatat agtaatacta aatacaagtt ttctgcaaaa ccaaattgtt ctgtaaaacc
    23701 agaacttaag cctgataaag ataactcttg taaggataag aatcataatg acaagaattg
    23761 caacaacact aataaacctg aggacaacaa taattcagac tctactaata agcctgataa
    23821 caataaacct gagtctaata aacctgaaga caacaataat tcaggctcta ctaataaacc
    23881 taataataat aaacctgagt ctaataaacc tgaagacaac aataattcag gctctactga
    23941 taaacctgat aacaataaac ctgagtctaa taaacctgaa gacaacaata acaataattc
    24001 agactctact aacaaacctg atgataataa caactcaggc tctacaagtg aaagtttttc
    24061 agcttaccaa aaagaagttg ttgacttagt aaatatagaa agagctaaag ctggattaaa
    24121 tcctcttact cttgattctt ctatatcaaa tgttgctaca aaaaaatctc aagatatgat
    24181 tgataacaac tatttttcac acaattctcc aacttatggt tctccatttg acatgttgaa
    24241 aaaatttgga ataagctata agacagcagg tgaaaatata gctatgggtc aaaaaactcc
    24301 taaagaagtt gtaaacgcat ggatgaattc tgaaggtcac agaaaaaata taatgaatcc
    24361 aaatttcagt aaaataggtg ttggagtagc acaaaaaagt ggtggttcaa tttattggac
    24421 acaaatcttt gtaggataaa atactctttt tccatacata tcaaaagagt atctctaagt
    24481 gataaaaaac acaaatgaga tactcttttg tatctatttt aaaattatca aatccaaata
    24541 tacatactat aaatattatt tgttctctta attttagtgt gtagaacaat atataaaaag
    24601 tattggcaag atgaaaatgg aaaacttaaa aaagatattt aataggtaaa aacaaaatct
    24661 taatatcttc ataaaaaaag gctgtctcaa aatagagata aggccttttt cattgttgaa
    24721 atgattaaaa tatatttgat ttcatacaaa aagagtgcct catgaactaa aaagctcact
    24781 ttgagacact ctcttttatc aatttatata agcattataa tactttaata ttattcagct
    24841 aattttttgt atccttcata tctttcttta gcatcagctt cagctttagc aaataatcca
    24901 tcagcttctt ctgggaattg tttagctata gcagaatatc ttacttgtgc aagtatgaaa
    24961 tctttgaagc ttgcagttgg ttcttttgaa tctaaagtga atgggttttt accttcagct
    25021 tttacttctg gattgaatct gtataaatgc cagtatccgc aagcaacagc ttgtgcttcg
    25081 ttagctacag ttcttcccat accttctttt aatccatggt ttatacatgg agcataagct
    25141 attattagag atggcccatc atgtttttca gcttctataa cggctttgat aaattggttt
    25201 ttatcagcac ccatagcaac ttgagctaca tatacgtttc catatgtcat agccatcatt
    25261 cctaaatctt tctttctaga ttttttacct gaagcagcaa acttagccat agcagcagct
    25321 ggagtagctt tagaagcttg acctcctgta tttgaatata cttctgtatc aaatacaagt
    25381 acgtttacat cttcaccaga tgcaagaaca tggtctaatc caccgtaacc gatatcatat
    25441 gcccaaccgt ctccacctag tatccattga gatctcttaa ctagataatc ttttctatct
    25501 tttatagctt ttactaactc tttagctttt tcatctgtac aatcacaagc tggtttttct
    25561 aataattcaa caaccttagc acttgctact ttagaagctt ctccatcatt tctagaatct
    25621 aaccactctg taaatactgc tttagcatct tcacagatac ccatagaaac taactctgtc
    25681 atagcatcta ctattttatt tcttatttgc ttaacagctg tgtacatacc aaatccatat
    25741 tcagcattat cctcgaataa agagtttgcc caagatggac ctttaccttc atggttacaa
    25801 gtataaggaa ttgatggtgc agaagctccc catatagaag aacatccagt agcattagct
    25861 atcatcattc tatctccata taattgtgta actactttaa tgtatgcagt ttctccacat
    25921 ccagcacatg ctcctgaaaa ctccattaat ggttgtctaa attgacttcc tttaacagtg
    25981 tttacaggca taacatcacc ttttggagct acctcatcag gatttactgc aaatgcccaa
    26041 ttatctaact ctgtatcaag ttgagtatct attggcttca taactaaagc tttttcttta
    26101 gctggacata tgtcagcaca gtttccacat cctgtacagt caagtggact aagttgcatt
    26161 ctatatttta atccttctaa tcctttacct aatgcttttt tagcttcaaa tccttctgga
    26221 gcattagcta attcttcttc agtaactaat actggtctta tacatgaatg aggacatata
    26281 aaagaacatt ggttacattg aatacagtta tctattatcc attcaggaac atcaacagct
    26341 ataccacgtt tttcataagc tgcagtacca caagggaatg ttccatcttc tataccattg
    26401 aatgtactta ctggtaagtt gtttccttct tgtgcagtca ttggtcttag tatatttttt
    26461 ataaattctg gttctttaac ttctccttta tctgcatcaa cagcattttc ccaagaagct
    26521 ggaacttcaa ctttaactaa agcatttatt cctgcatcaa cagcagcata gttcatgtta
    26581 actatttttt cacctttttt accataagct ttaactatag aatcttttaa gtatttaaca
    26641 gcatcttctt ctggtattat ttcagctaat ttaaagaatg cagattgcat tatcatattt
    26701 attctgtttc caagacctat ttcttgtcct agtttaacag cgttaactgt atagaatttt
    26761 atatcatttt tagctatata ttgcttcata tgagctggta aatgttcttc aagtcctgct
    26821 tggtcccata tagtgttaag tacaaatgta ccaccttttt taagaccttt taataaatca
    26881 tattgataaa catatgattg tttatgacag gcaatataat cagcttcatc tattaaataa
    26941 gtagctctta ttggagtatc accaaatctt aagtgagaca tagttatacc accagatttt
    27001 ttagagtcat aatcaaagta agcttgagca tatttttcag tatggtcacc aattattttg
    27061 atagcttgtt tattagctcc aacagtaccg tcagaaccta atccccagaa cttacatctt
    27121 atagttcctt tagaagctat ttttattggc tcagatggag ttaaagaagt attagttaca
    27181 tcatcaacta tacctactgt aaatccattt ttaggttgtt ctgaaactaa gttatcaaaa
    27241 acagttttta tatctgaagg agtagtatct tttgaaccta atccgtatct tccacctatt
    27301 atcataggag cattttcttt tccatagaat acatcacgta catctaagta taatggttca
    27361 ccagttgaac ctggctcttt agttctatca agtacacata ttctttcaac agtagatggc
    27421 atagcatcta agaaatgttt cattgagaat ggtctatata aatgaacttt aactaaacca
    27481 tatttttctc ccttagcatt taagtaatct atagtttctt ctattgtttc tgttactgaa
    27541 cccatagcta ttaatacgta tttagcatct tctgctccat agtaatcaaa taaactatgt
    27601 tttctacctg ttaaattact cattttttcc atgtattttt caactatacc tactatattt
    27661 tgatagtatt tattagaagc ttctctagtt tggaaatata tatctgggtt ttgagcagta
    27721 ccacgagcaa ctggatgatt tggagataaa gcattatctc taaatgcttg aactgcttca
    27781 aagtttaata aacttgcata atcttcattt tctagtaatt caactttttg gatttcatgt
    27841 gaagttctga atccatcaaa gaaatgtata aatggtaatc taccttctat tgcagctaaa
    27901 tgtgcaacag gtgctatatc agctacttct tgaactgaac cagaagctaa taatacacat
    27961 ccagtttgtc tagcagccat aacgtcttgg tgatccccaa atattgataa cgcttgagat
    28021 gctaaagcac gagcacttac atggaatact cctggtaata actctcctgc aactttatac
    28081 atgttaggta tcattaataa taaaccttga gatgctgtaa aagtagaagt taaagctcct
    28141 ccttgtaaag aaccgtggaa tgttcctgat gcacctgctt ctgactgcat ttcaacaaca
    28201 ttaactgttt gtccaaatat attttttctt ccttgtgatg cccactcatc aactacttca
    28261 gccatagttg aagatggtgt gattggatat atagctgcta catctgtaaa cgcataggca
    28321 acatgagctg cagctgtatt tccatcaagt gttttcataa acttagccat aatatgtatc
    28381 ctccttgata gctacaattg tacttgttta taacaagtct atttttttat atttacatat
    28441 aatttacaca acaaaactat aaacacacat atagtcgcgc aaatactcta tcttctaata
    28501 taatactaca gattagataa aattcctttg aaaattgtaa attaattaca tatttaagta
    28561 gatttttttt aaaattaaat atgttaagtt tttttcataa ttttgtatac aatatataat
    28621 aaattaagtt agatttttca aactttttta tctatttgtt catatta
//
LOCUS       DAMJWC010000051        28604 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMJWC010000051 DAMJWC010000000
VERSION     DAMJWC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.051"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            59..505
                     /locus_tag="PC503_002561"
     CDS             59..505
                     /locus_tag="PC503_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2528527.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            507..1601
                     /locus_tag="PC503_002562"
     CDS             507..1601
                     /locus_tag="PC503_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF2528528.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            1689..2219
                     /locus_tag="PC503_002563"
     CDS             1689..2219
                     /locus_tag="PC503_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2528529.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(3155..4531)
                     /locus_tag="PC503_002564"
     CDS             complement(3155..4531)
                     /locus_tag="PC503_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528530.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDEKDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDSIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            4799..5971
                     /locus_tag="PC503_002565"
     CDS             4799..5971
                     /locus_tag="PC503_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2528531.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYAIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            5985..6632
                     /locus_tag="PC503_002566"
     CDS             5985..6632
                     /locus_tag="PC503_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528532.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            6634..7143
                     /locus_tag="PC503_002567"
     CDS             6634..7143
                     /locus_tag="PC503_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2528533.1"
                     /translation="MSQQNTGNVIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(7507..8619)
                     /locus_tag="PC503_002568"
     CDS             complement(7507..8619)
                     /locus_tag="PC503_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2528534.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            8917..9183
                     /locus_tag="PC503_002569"
     CDS             8917..9183
                     /locus_tag="PC503_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HDF2528535.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILTIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            9428..11155
                     /locus_tag="PC503_002570"
     CDS             9428..11155
                     /locus_tag="PC503_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528536.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            11155..12945
                     /locus_tag="PC503_002571"
     CDS             11155..12945
                     /locus_tag="PC503_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528537.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(13107..13415)
                     /locus_tag="PC503_002572"
     CDS             complement(13107..13415)
                     /locus_tag="PC503_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528538.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(13677..14225)
                     /locus_tag="PC503_002573"
     CDS             complement(13677..14225)
                     /locus_tag="PC503_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528539.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(14328..14999)
                     /locus_tag="PC503_002574"
     CDS             complement(14328..14999)
                     /locus_tag="PC503_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2528540.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            15395..16300
                     /gene="garR"
                     /locus_tag="PC503_002575"
     CDS             15395..16300
                     /gene="garR"
                     /locus_tag="PC503_002575"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF2528541.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDVKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            16436..17818
                     /locus_tag="PC503_002576"
     CDS             16436..17818
                     /locus_tag="PC503_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2528542.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            17889..19325
                     /locus_tag="PC503_002577"
     CDS             17889..19325
                     /locus_tag="PC503_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF2528543.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNGGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(19511..20365)
                     /locus_tag="PC503_002578"
     CDS             complement(19511..20365)
                     /locus_tag="PC503_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528544.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(20633..20956)
                     /locus_tag="PC503_002579"
     CDS             complement(20633..20956)
                     /locus_tag="PC503_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2528545.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNKNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            21159..21788
                     /locus_tag="PC503_002580"
     CDS             21159..21788
                     /locus_tag="PC503_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528546.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            22100..22609
                     /gene="ruvC"
                     /locus_tag="PC503_002581"
     CDS             22100..22609
                     /gene="ruvC"
                     /locus_tag="PC503_002581"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF2528547.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            22602..23204
                     /gene="ruvA"
                     /locus_tag="PC503_002582"
     CDS             22602..23204
                     /gene="ruvA"
                     /locus_tag="PC503_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF2528548.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            23311..24330
                     /gene="ruvB"
                     /locus_tag="PC503_002583"
     CDS             23311..24330
                     /gene="ruvB"
                     /locus_tag="PC503_002583"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF2528549.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            24648..25673
                     /gene="queA"
                     /locus_tag="PC503_002584"
     CDS             24648..25673
                     /gene="queA"
                     /locus_tag="PC503_002584"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF2528550.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            25685..26170
                     /locus_tag="PC503_002585"
     CDS             25685..26170
                     /locus_tag="PC503_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528551.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            26249..27370
                     /gene="tgt"
                     /locus_tag="PC503_002586"
     CDS             26249..27370
                     /gene="tgt"
                     /locus_tag="PC503_002586"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF2528552.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            27504..27797
                     /gene="yajC"
                     /locus_tag="PC503_002587"
     CDS             27504..27797
                     /gene="yajC"
                     /locus_tag="PC503_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF2528553.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            27855..28217
                     /locus_tag="PC503_002588"
     CDS             27855..28217
                     /locus_tag="PC503_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF2528554.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            28283..28426
                     /gene="scfA"
                     /locus_tag="PC503_002589"
     CDS             28283..28426
                     /gene="scfA"
                     /locus_tag="PC503_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF2528555.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
BASE COUNT        10831 a         3299 c         4870 g         9604 t
ORIGIN      
        1 ttaatataat atagttgata tagtcaaaca tattataatt atagaaggga aatttaagat
       61 ggattttaaa aatttacagt atgaaagttt gtcatatatt atttgtaact tgcaaaaaaa
      121 ctttaaactt tattgtgaaa aatgtttaaa accatataaa cttacgaatg gtctatattt
      181 ctatttaatt tatattaata aaaataggaa ttgttctttg aatgatgttt ctacagaatt
      241 tgaagttgat aaagctcata caacaagaac tatatctagg ttagaacaag atggatacat
      301 agaaaaaatc caaaacccta atgatagtag agcttttcag ttgagagtaa cagataaggg
      361 tgaggaagta ttaggggata taaaaaacat attttcaaag tgggataatc acataaaaaa
      421 agagttctcg gatacagaat ataaagaact ggtaaagaat ttacatgtgg taaaggatat
      481 aaaaacagct gtggaggaag aataggatgt attgtaattt attaaaacca attaaaattg
      541 gaaatttgga attaaaaaat agagtatctt ttgcacctac aagcatgggt cttaaattgg
      601 aagaaaaaat taaaaagttt tctgatattg ctaagtcagg agtagctctg attactctag
      661 gagatgtatc tattagacct agttttcata aggtagctat aagcctatcg gatgaagatg
      721 gagtcatgaa atacaagaaa attgtagatg aaatacacaa ttctggtgca aaggtatcag
      781 cacaactatt ttgttcagat tatgatgtta atttaattaa agatactatg aatatgggaa
      841 ttacttcaca tgatgagata aaaaaaataa tgaatgacgg agtaaaagat tacataacaa
      901 atatgcccaa agaagaaatt aaaaatatta taaatttatt taaagtaaca gcattgaatg
      961 caaaaaaagc aggttttgac atgattcaaa ttcatggtga taggcttgta ggaagttttt
     1021 catcaagtat atttaataat agaaatgatg aatatggtag aacgtgtgat aatagaagta
     1081 gatttgcaag cgaaataatt agtagtatcc gagatgaagt taaggacatt ccaatagact
     1141 ataaatttgc aataagacaa gaaaatcctc attatggaaa tgcaggagtt ttactttcgg
     1201 aagttgagta ttttgttaaa aaatttgaat ccctaggtgt aaacagtttt catgtaacac
     1261 ttgcaaatca ttcaaaatta gaagatacta taccaaccaa taatcatcct tactttaaag
     1321 aagaaggctg ttttttatat ttagctgatg aagtaaagaa acacacaaat cttccagtat
     1381 gtggggttgg aaaattgtct agcccagatt ttatagaaag tattatttca aataatagag
     1441 tagatatggt ttctatgtca agacaattac tagcagatag taattggtta cagaaagtaa
     1501 aagatggaag agtagatgag attaaaaagt gctgttattg taataagaag tgtgcagatg
     1561 ctttacaaac acgctctcag tttggatgta tactagatta gaatatcctt ataaaaataa
     1621 ataatttgtt aaggttaata tatttttggt gatttagata aatatttaga taaagaggag
     1681 gagacatcat gaaaagttta gttttatatt caagtttaac tggaaatact aaaaagattg
     1741 cttatactat atatgatgaa attcaagaag aaaaagacat taaagatgta aatgaattag
     1801 ttgattatgg tattgactat gaaaattatg atatagtatt cttaggctat tgggtggaca
     1861 agggaatttg tgataaaaat tcaaaacaag tgcttgaaaa tattcacaat aaaaagatag
     1921 cactatttgg aacaatggga gcaagtaaaa aaggaagtta tggagctagt ataatagaaa
     1981 agatagaatc aattatccca aaagataatg aaatactagg ttcattcata tgtcaaggta
     2041 agatagcaga aggattgaaa gcaaaatata aagagatgtt aaaactttct cctgacaacg
     2101 aacatattcg ccaacaatta aataaccatg aggaatctca aagtcatcca gatgaacaag
     2161 aaatatatga agccagtatg tttgcaaaaa atatgatgat taaagctagt attgtgtagt
     2221 agttaaacaa taagttcata taagatatag aataaataat ttagtaaaaa agtatagcaa
     2281 ataatttgct atgctttttt tatgaaatca aaaaaataat aaaaatactt gactgtaaac
     2341 cttgtttata cattatttta tagaaaataa gatagtttta aatataaaaa aagatatatt
     2401 attgaaagga gatattattg tatgaaaact tataaaagat aattagtttg attttaagat
     2461 atactaaata tacaatttta tagagtgaaa atatttaaga ctatattata gttataaatt
     2521 aatagaatag agaggtagtg tttaaattgc aataacagta tttcaaaagt tgccacctca
     2581 aattcctatc caatggaata atggtgtagc taattatgta gataaaaaat ttatttatgc
     2641 ctaccctgtc atttgtgttg tattcagaat acttttacgt ccatttatat ggagatggtt
     2701 acaaatacat gctttttata gtgatactat tgcagattat ttaacgaatt ttatgtgttt
     2761 tgtagcgttg tctatagaaa tattctctat attttttatt tacaatattg tcagacatgt
     2821 tacaataatt atttttatag atatacttgt atttattgct ttactgataa taggtgtgta
     2881 taaattattt aaaaaataca attaattttt aaaaataagt aataagtgat agtgtaaaaa
     2941 gtagccactg caaattatgg attgtagtgg ctattttatt atttgtatat gaaattattt
     3001 tgtttttcta ataagttacg atatattatg gtttatttca ctgataaaag gtttaggtat
     3061 tttaaagtaa aaagttgtat attctaataa aatttaaaca ttttgattct ttaaaattag
     3121 agaaaataca ttgcttttat taaaaaatta aatattaaga atttaatttc tgcatcttat
     3181 ttagaaaaga taagaaatca actttatata ttttttttgg ccttcctctt tgattatcga
     3241 gttttgtatt tacaatagtt gcaattcctg ctttatataa gatactcaat attctattag
     3301 cacttctaag agttatgttc atatagtctg ctaatatttc tgctgacaca ttatttgaat
     3361 ttctatcatt aatcatacac atgattttag atacatttgt attagataga ggtataaaag
     3421 aagcaacttt attggctatt gagctatctt caatattatt agaattttta tttgaatata
     3481 aagggcctat tgtatcatta gtatcattta ctataaaagt acagtttcca ttcaaagaag
     3541 cagatttacc attagcttga cgagcatttt gctctgcatg aatatttgta tttccaatgc
     3601 cccaacctat atttaagcta tatttaattt cttttaaatc ttctgaaata aaaaaatctg
     3661 tatagttatt ggtcatattg tttaacattt ctttagtagt gtgtatctct attttcatat
     3721 catttttttt gacctgaact ccatagaatc catgtcttga tagagaattt aatatagtgt
     3781 tatatatttg attttgtatc tcatcatttt taaatatcaa atcttcattt atgtactctg
     3841 aactatttac tgtaactata caagttgcag atttattttt gtctaagttt tgtaatgtta
     3901 tttcattcac cagagattta aatgtattca ggattgattc tgtagatgga accatgtaaa
     3961 tagaatcata tccaagttta ttaagttcac aactaatgat gtaatttcta gtaaaagaaa
     4021 ggttaatctt attatctcgc aataagtcta aatgtatttc caataattta tcatttaatt
     4081 ttttaaagtc atatacaggt tgagggatat taaaatcttt aattgtatat ggacatttat
     4141 tagagtctat taatgaatat atatcataat aattgttgtc ctctcttaaa aaatccataa
     4201 atgattttgt aaagtcaata tctttttggc tatttaataa tttgaataag tatttataaa
     4261 aatctttttc atcaagcttt aaaaaattta atggaacttt tatgtctttt atatttatta
     4321 taagttcact atatggaact ataccactgc atacaaatcc atcaaaatta tctacttgct
     4381 catagtatat attaggtaaa ttattaaaag gattctcccc tttaagctca ataaatgtaa
     4441 tttcacaagt atcatttaat tctttaagag cttgtttaaa cttatctgac ataaaataag
     4501 atgttgtcaa aaaaccaatt ttatatttca taaaacctcc tttaaaattt cgagagtatt
     4561 gtaactaatc aatcaattta taacctcatt ttataatagt agataaaacg cgtcaattta
     4621 ttttacaaaa ggaaaattga aagaaaaatc agaaaatata aaaaagactg aaaaatatgt
     4681 tgactgtcaa gaataattgt gctattttgt aattaaggac tagtctttta agatttccta
     4741 aaataaactt agattttagg aaagaaatac attttatttg aaaataaagg agaagattat
     4801 gaatacatat ttaaatgaaa tttctaagtt tgttgatgag aatagagaag aaatagtttc
     4861 attatggaaa gagattgtta atatggaaag ctatacacat tgtaaagaaa gcgtaaataa
     4921 attggctaag agattaaagt ttgagtttga aaaagaaggt ttagattgcg agttagtaga
     4981 tgttggagat aatggtagta cattgatagg tacacttggt tccaatatag ataaaaagcc
     5041 aataattttt tcaggtcaca tggatactgt ctttgaaaca ggtacatttg gagagaatcc
     5101 atttaaaata atagaaggaa aagcatatgg cccaggtgtt ttagatatga agggtggtat
     5161 aataatttcc ttatatgcta ttaaagcatt aaataaaata ggatacaaag aaagaccaat
     5221 aaaaatagta ttttctggag atgaagagat aggacataag gattcaacag gtgcagatgt
     5281 tatattgagg gaagcaaaag gtggtctttg tgcttttaat atggaaactg gattagtaga
     5341 taatagtttg tgtgtaggta gaaaaggaag aataggatgt aatatacatg taaaaggtgt
     5401 agaaacacac gcaggtaatg attttgaagg tggaagaaat gctatagaag aaatggctaa
     5461 taagatacta cgcatacaaa aattgactaa tttagatgtt ggaactacag taagtgtaag
     5521 tgtgattaag ggtggaagag tggaaaattc tattccagaa gattgtagta taaaagtaga
     5581 ccttagattt gaaaaagtag aagaaatgga gaatgttaaa gaacaagtta gagagatatg
     5641 taaagaaact tacatagaag gaacttctac agaagttaat tttataagtg aaatgatgcc
     5701 atttgaaact acagaagatg ttatgagatt tcatacattt gtaaatgaag tgtcaaaaga
     5761 aaatggattt ggagaattaa atgctaagag acttggaggt agttcagatg caagttattt
     5821 aactattgca aacgttccta caatctgttc atttggtgta agaggagaat ggaaccacac
     5881 atcaagagaa tatgcagtag tagattctat gtttgagagg gtgaaattaa tttctacagt
     5941 tattttaaac ttagataaat ttgaggtata aagggggatt ttatatggat gtaacagctg
     6001 gagataataa ggtaacatgg aaagggtatt tatctttatt tgtattgata gtattatttt
     6061 caggagtgtt taaagatagt caaggcttcc ttaaagcatt agattttgct aatctgacag
     6121 gttcatttgg tactattgca gatggtgtag actttatggg taaaggagga acgggagcaa
     6181 aagatggttt cttatttgct ctgactttga ttccaactgt ctgttttgct gtaggtctta
     6241 tagatgtagt tgaatctatg ggaggaatga aagcggcatc aaagatattt aatccattgc
     6301 ttagacctct gcttggtata cctggaatag caggaatagc atttgtatct tcatttacta
     6361 gttcagatgt agcctcaata atgacgaaag aattatttga aagtggggaa ataacagatg
     6421 atgaaagaac tatatttgta gcatatcaat atgctggttc agctgttata ctgaacacaa
     6481 taaatactca agctccactt ttaccaatag cattattggc attaggtcca ataatactta
     6541 tagagatatt ctgtaaaata cttggtgcta atctagttag attaatcata ggtgtaagaa
     6601 ataaaaagaa taaggctaag gaggctgtgt agtatgagtc aacaaaatac tggaaatgta
     6661 attgtaaata gtaaacctaa gaaaactgct gttgagatat ttatgggggg agcaaaaaaa
     6721 ggtttttaca taggtgttga acagatatta ccagccatga taatgggtta tgtaatagtg
     6781 cagtttttac aattaactgg tttagttgat attttaggaa atatttttgg accagtaatg
     6841 ggtatttttg gactacctgg ggaatctgtt gtagttttga tagcagcatt ctttgctaag
     6901 gcagcaggag cagctacagc tgcaaactta tttgcacaag gtctaatcac tgcaccacaa
     6961 gcaaccatat taattatgcc atgtatgtta atgggtactc tagttggtca ttatgccaga
     7021 atagtgcttg tagcaaatgc cagtactaag tatagaatgt tactgttggc agttcctata
     7081 tttgatgcaa tagtggggat gttgatagta agagttttac tcactgttat gggattaatg
     7141 taaataacat aaaattataa cctaactata aatgatatat aagaattaat atatacaagg
     7201 attaatgagt agtaattgat atatagtaat aaactaagat agtaattaat gtgtatatta
     7261 attaaaaaaa gagagtatct caaagtgaac tttttagttc atgagatact ctttttgtat
     7321 gaaatcaagt atattttcat aatttcaaca atgaaagaga ggcttatctc tattttgaga
     7381 cagcctcttc ttttaaattt atatttctag aatttatgtt ttttatttat ccaacattaa
     7441 cattagttat tagcaataat tttaagaaaa atatactttc atgttaatat cagaataaat
     7501 gtgtttttaa aggatgattt gttttgaatt ttcacgaata tctacttcta tgactttttc
     7561 tattgtatct cctctaaaac ctaataaatt acttgtcaag tttgcagtgg aacaagaatg
     7621 attaggtata attcttattc tatcaccaat ttttatatca gtttcaccat ttactttaat
     7681 ttttccaact tcttctgaaa gtgaatcaat agtaagttct ggatgtccac ataccctacc
     7741 ataaccaaca atactactat ttccatgtgc acctttatca agtccaaggc acttacttcc
     7801 acaatcaatt aaatagtatc cactgctatt ttttgagatt acagtgcaca caacagtaag
     7861 agcacacata tcttcagtag cacaacctaa acctatctgt atagcatcat agtatacata
     7921 gtttccaggt cttacagcag ttatagtttt agaagcagct tcagattcaa ctgttggagt
     7981 actaccagaa gcgacaattt ctatattaaa tccattatca gttagagctt tgtatgcttt
     8041 ctccatagaa gaatcttctt gaacacaaac atctggaaca ccttctggag aactacaacc
     8101 atacacttga cctggatgcg aacttatacc aacaatcttg atgttttcta gcttagaaat
     8161 ttcagtagca agttcaacca ctttttctgg ttcaacccca aaacggtgta agccacaatc
     8221 tacaataata agtagcttgc actctatttt tgatttagaa aaagcttcac tataagcctt
     8281 agcacattct atattatctg tagcacagat taaatttatt tttgatgcca tagtcacaat
     8341 tctatttata tttacttctc ccatgtaagg ataagccaac ataatatctt caaaacctgc
     8401 ttttatcaga gcttcacctt catcaagtgt tccaactaga aaaccactag cacctgcatt
     8461 tttttgaagt ctcgctatgt aagtactttt atgtgtctta agcataggcc aaagttgttt
     8521 attattattt gtacaaattt gttgaatttt atctatattc ttttctaact ggtctaaatc
     8581 tagcaaaaaa tttggagtag cgacttctga aattttcatg ttatttacca cctttcaaca
     8641 aaagtaaatt aactataagt attataatta ttatattagt aatatcggct ttataatatt
     8701 aatagcttat aattatatta tagaactagc gttaacagag agcaatattt atttgtaata
     8761 attagaattt tcaataagtt agtgtagttt taaattattt atataatata tttttaattt
     8821 tatacaaagt ttatttaaat tagtttgagg atttattaat agggtattat tgaatgagta
     8881 aaaaagtgat gtttacatag aataatcaca ctataaatta atttagaacc taaaaaatta
     8941 attgagcaaa ttggaaaaga gaaggataaa aaagatattt ggatagttgg tggaggcgat
     9001 atagtaaaat tatttatgaa agataactta attgatgatt attatatata tatattgaca
     9061 ataatattgg ggagagggat ttcactattt aagtctggta tagataagac taatttgaat
     9121 tttaagaaag ctagtaatat tggagaactt gtaaaattgg aatacagtaa aaaacaaaaa
     9181 taaattacat gccaatttgt tacaatgtta tgaaacgaag catttaaaag acttttggct
     9241 atatgaattg acattacttg tcaaatatgt taacatataa gcgacttgtc ggagggtgta
     9301 ttaaaaagaa tatgctggag aagagagtgc gttaactctt ttctcctttt tttataaaat
     9361 taagcattta taaatttagt attattacat gattacacta tctcaaaaat taagaaagga
     9421 gaaaaatatg aaattaattt taagttattt aaagaattat aagttattaa tagtattaaa
     9481 catactggct atatttagtt ttgcattagt cgagttgggg attccaacta taatagctaa
     9541 aataattgac aatggtattg caaatcagaa tatagcttac ataaaacaaa tgggaatagt
     9601 gattgttatt atttctatta taggggttgt aggtagtata ttgttgggtt attgttctgc
     9661 taaggtatca acaagtgtaa ccagagatat aagaaatgac atatttgaga aatcacaaga
     9721 attttcacat actgaataca ataaatttgg aatttcttca atgattacaa gaacaacgaa
     9781 tgatgcattt caaattcaac aatttgttaa tatactacta aggactgcct tattaactcc
     9841 agttatgttc attataagta taataatgac aattagaaca agtgtggaac tttctatagt
     9901 attggctata tcagtacctt ttataattat tggagtagca ataatagcaa aagtatctca
     9961 ggcaatatct tcaaaacaac aaaaaggact agataaatta aaccttatat cgagagaaaa
    10021 tttaactgga ataagagtaa ttagagcttt tggaaatgat gattatgaaa cagagcgatt
    10081 tgaaaaaaca aatacatatt atgctaatgt ttctaagaaa ctatttaagc ttatgtcaat
    10141 tactcaacca gcattctttt tactattaaa tatagctgtt ttggctgtat tttggatttc
    10201 aagtgagaag ataaatattg gagagcttca agttggacag ttggttgcat ttttggaata
    10261 tcttttccat gccatgtttt caattatgct tttttcaatg gtatttatta tgtatccaag
    10321 agcagaggta tctgcaaata gaataaaaga actattaaat gaagaaccat tgataaaaaa
    10381 tcctgaaaat ggaattaagg atactgaaaa taagggtatc atagaatttg ataatgtaac
    10441 ttttacctat ccagatggag aagcttctgt acttaaggat atttcattta ctgcaaaaac
    10501 aggtgaaaca gtcgctttta taggaagtac tggtagtggg aaaagtactc taattaactt
    10561 gatacctaga ttttatgatg taacagaagg tagcattaag ataaatggag tagatataag
    10621 agaatatgat ttaaaagctt taagaaaaaa gataggattc atacctcaaa aatcactgct
    10681 ttttactggt agcatagcaa ataatattag atttgggaaa cataaggcag gagagtcaga
    10741 attagaatat tccgcaaaag ttgcacaagc atatgagttt atatcaaaaa aacctagaaa
    10801 gtttgatgaa ttgattagtg aaggtggagc aaatgtatca ggaggtcaaa aacaaagact
    10861 ttctattgca agggctatta taagaagacc tgaaatatac atttttgatg atagtttttc
    10921 tgcacttgac tttaaaactg atgcaatact tcgtgctaaa ttgaagaagg aaacaaaaga
    10981 tgcaattgta ttgattgttg cccagagaat tagttctatt attgatgctg ataagattat
    11041 agtactcaat gaaggacaag ttgtaggaat gggaactcat aaagaattat taaaaaactg
    11101 tgaaatatac tatgaaattg caacatctca gttaaaaaag gaggaattag aataatgaaa
    11161 aagtctaaag gttttaagaa aacaattggt agacttcttc catttgtaaa gaaatataaa
    11221 ttttccttta ttatagctat tatatgtata atttcagcag ctactatgaa tgcacttgca
    11281 cctaaaactg aaggattgat aataacacaa ttgactaaag atgtaattag tatcgcaaaa
    11341 ggagtaccag gggcttccgt aaattttgat tatgtaacaa aaatattggt gattttagca
    11401 tgtatatatt ttgccaatgc aatttttacg tatacttcaa gttttctact tacgaatgct
    11461 attcaaaaca caatgagaga tttaagaaat gaagtcgaaa ataaaataag aagattgcct
    11521 attagttatt ttgatagtaa tagttttgga gatgtattaa gtcgtatatc aaatgatgta
    11581 gatacaatat caaatgcatt gcagcagagt tttatgcaaa ttgtaaactc aatcttagtc
    11641 ataattttgg cactttcaat gatgtttaca attaatatat atatggctct tatagctctt
    11701 tttataattc caattagtta ttttgtatct aaatttgtag taaaaaaatc tcaaagtaga
    11761 ttttcattgc aacaaaatgc tcttggaaaa ttaaatggaa aagtacaaga aatgtatact
    11821 ggatttaatg aaataaaact atatggtaaa gaagaagatt ctataaaaga atttaaaaaa
    11881 gtaaatcaag aactttgtga aaatggattt aaggcacaat ttatatcaag tatgatgaat
    11941 cctatggttt cattagtaac ttactttgga attgcagctg tggcagttgt cggttctata
    12001 tatgcagtaa gtggaggaat aacagtagga aatttacaag catttgtgcg ttatatatgg
    12061 cagataaatc agccactttc acaaatgact cagttatcta cagtaataca atcttctttt
    12121 gcagctatag aacgtgtatt tgaaatttta gacgaagaag aggaaatacc tgatgttgaa
    12181 aatccagtta agatagaaaa tgtaaaagga aatgttacat ttgagcatgt taattttgga
    12241 tatggagaaa attcaacttt aatagaagat ttaaatgcag aagtaaaaag tggtcagatg
    12301 gtagctattg ttggacctac tggagcaggt aaaacaacat taataaactt attgatgagg
    12361 ttttatgatg taaagaaagg tgctattaaa attgatggag tagatataag agatatgaaa
    12421 cgtaaagatt tgcgttcaat gtttggtatg gtgcttcaag atacatggtt atttaatgga
    12481 accatttttg aaaatataga atatggtaga tttggggcta ctaaagaaga aattatacaa
    12541 gcagcaaaag tagcaaatgt tcatcacttt ataaccactc ttccagatgg atacaatatg
    12601 tttttaaatg aagaagcatc taatatatct ctaggggaaa aacagctttt aaccatagct
    12661 agagctttta tatcagaccc ttcaatattg atacttgatg aagctacgag ttctgttgat
    12721 actaggctgg aacttatgct tcaaaaagca atgagaaatc ttatgaatgg tagaactagt
    12781 tttgttatag cacatagact ttctacaatt cgcaatgctg acttgatttt agttatgaat
    12841 aatggaagta ttatagagca ggggaatcat gatgaattaa tggaaaaggg tggattttat
    12901 gagaagcttt ataatagcca atttgcagac aaagaatcag aatagataac ataaactttt
    12961 gtataaaatt ttgtatcaaa ttcaaatatt aatcatataa ttaaaaagag tatcagtaag
    13021 ttgttttttt atagatttac tgatactctt tgattttaag actaaaggta cttatgattg
    13081 gtacttataa ttcacaacta gtcttgttac atctgataac cagaattaca gtacttttct
    13141 tttttacctt tttgttctct aacatataac aattcgctta acttatcaat gtaataacca
    13201 tcatcactta tgcgaattaa actagtcaga taatatccat ctttgcttct aggaatcttt
    13261 ttatttattg ctaaatcaat agctgtcttt gctgcttcaa aatgctttaa atgtgtatga
    13321 ccttcttcaa aactctttct agtattataa actacataac cttttttaac ttgaaaaact
    13381 ataaattctt tcttttcata tattttatta aacattcaat cagcccttct caagatagtt
    13441 ttatagcata acattagaag cttctaaaaa attttacaaa gaacataaat attttataaa
    13501 ttataaatct aaaactataa tttataaaga taactttctg attatttata tgataattca
    13561 tatagattaa aagtaaatta tctttaggtt aaacaaaagt aaaataaaag actagttata
    13621 atatttatat gaaaaagtac aaaatatagt atatgaatat agaaaattta aatcatttat
    13681 ttacagtttt tatttccata agtatattta ccttcagata ccttgtcatc atggaaatat
    13741 attctttcac aacttttatc tccccataga atgttttttg ttattttatg ggacgtatct
    13801 cctgtaaata cttcagctac agtagtatct gtaacatcac agtaaagaga agcaaatttt
    13861 ttaaaccaag gattttcctc aaatcttaaa agccaagaag ctccataggg gcaatgtaac
    13921 tcttcaaatt caggaaccca tcctagaaat ggaacatcag ttgtgctaat aatattgtct
    13981 gcgattaatt catctccatt ttcatgagct ctctctctca tagcaatagc tctttcttca
    14041 gacctttcaa ataaaacttt tcttaatatt tcgctagttt tatcttcacc aaactcttca
    14101 aataacactt tggaaaaata aaaatataaa tcaccaaaat gtttgcatgc catacgaact
    14161 tcttcaatag cataatcttt gtcaatagtt tcattagtta caacatcttc gttcaaaaaa
    14221 atcactcctt agaataagta ttagttacaa tataattata gaatattttt tataaattag
    14281 gaaattaatt tgagatagat atatttttaa taaatgaaag tataatacta aaataactta
    14341 ttgttacaaa aatcttctaa attaatgtat ttaggagttt ccatatgaat gagagtagtt
    14401 ctgtaaatat cttcaataca tccatttgca atattattaa aaatatctgt gtgctctttt
    14461 aatgttgttt caagccttcc ttcatgtgac aatgaatcga gagctaattt ttttattctg
    14521 tacatataat tgttaaacat tttgtcaaat tcagtatttt gagcatatga aactatagtt
    14581 gtgtgaaata atgtatcgta ttctgcaaat gagtttaaat ttttatcacc taataaaata
    14641 tctttttgtt tatctaaaag atgttttaat ttacttatag tttctactgc tctagcttct
    14701 ttgtattgac ttgtaattaa aaaagtacaa aatccttcta ttgcagagcg tatttggaat
    14761 atctctacaa tttcatttgc tgtaatttga tggattctaa atcctttgct tgggattata
    14821 tctataaatc catcttgact aagtctttga agagcatctc ttataggtgt tctagagata
    14881 cctatttcac tagcaagttt tgtttcagaa tatatttcat tttctatcat ttctccagat
    14941 agtatcaatt cttttaagta gtcatatgct tgttcttgta atcttttaaa tgtagccata
    15001 cttaataata cccccctaaa caatataaaa atacaaaaac ttatataatt ttaagcatac
    15061 aacatagtga aaataaggtc aatcttttgc aatttaaatt gcagataaga ttaaaaaata
    15121 taaaaaatta ttgaagtgtg aagcatgatt aacattaaag gcagattaat taaaactaat
    15181 tgaaattagt taaaatacaa aactgtaaaa gtagtatatt atatttgaaa acaatagtat
    15241 gtattaaaac ttatatagga tgactaaata taataaatga ctttaaaaat tactatttat
    15301 tgttaaaata aatactttta tattttatat tgaccggtat actggtatgt agtatactct
    15361 aaaacataaa aaacgttttc aaaaatgtga agatatggag ggttataaaa tgaaattggg
    15421 atttattgga ttagggataa tgggaaagcc aatggcaaaa aatttattaa aagatggatg
    15481 taatcttttg gtgtatgaca ttaataaatc tgctgtggat gaacttatat catgtggagc
    15541 aaaatacgca agtgttttag aaatgggtca agaatgtgat attgtattta caatccttcc
    15601 aaatggaact attgtgcagg atatattgtt tgggatggat ggattggcaa aaactttaaa
    15661 agaaggaagt atagtagtcg atatgagttc agttactcct acagaatcaa tattgtgtgc
    15721 aaataaatta aaagatatgg gcttagaatt tatagactca ccagtaagtg gaggggagcc
    15781 aaaagcgatt gatggtacac ttgcttttat ggctggtggt aaggaagaaa tttataagaa
    15841 agtagagcca ttttttaata taatgggaag ctcatctatt ttaattggag ataatggtag
    15901 tggaagtgtt acaaaactta caaaccaagt aatagttaat ttgacgatag cagcagtttc
    15961 tgaggcattt gtacttgcag caaaagcagg tgcagaccca gaaaaagtat ataaggcaat
    16021 aagaggaggc ctagctggta gtacaatatt ggatgtgaag ataccaatga ttatgaatcg
    16081 tgattttaaa ccaggtggaa aaatatctat taatttgaaa gatattaaga atgtaatgca
    16141 aacagcacac aatttagatg taccactacc tatgacaagt caattattag aaattatgca
    16201 gacattaaaa gtacatggac atttggaaga tgaccatagt ggaatagcac agtattttga
    16261 aaagttggca ggtgttgaaa taaaaaaaca cgataattaa tatttaaata tatcaatata
    16321 attaaataca tattattagg attagattat ataaatacag cgaggttaag ttatcatagt
    16381 aaaagaaaaa taaaattgat aaataataaa gtagaatgat aaaggggtaa agattatgat
    16441 tacaggatat ggacttttga tagcatttgt tatatctata ggaattttac ttgtatcgat
    16501 tattaaattt aaagtaaatc cgtttttggc attactgata acatctataa ttacaggctt
    16561 tatggttaga atgcctataa atgaaatatc aaccacaata tcgactggat ttggaaatac
    16621 attaggtagt ataggtattg taattggact tggaataata tttggaaata ttctttcaga
    16681 atcaagagca acagaatcta ttgcaaaggg gttgttagct aagactggag aaaaaaacag
    16741 tgctttagca gtaactacag caggtttttt aatttcaatt ccagttttta tggatgcagc
    16801 ttttgttata atgatgccta taattaagta tgtttcgaga gtaactaaga aatctctaat
    16861 ggtttttgta tgtgccttag gagttgggac tatagtaggt catgcacttg taatacctac
    16921 accaggacct ttggcagttg cagcaaatgt aaatgcaaat gtaggtagtt ttatacttta
    16981 ttctataatt gttgcttttc cagcagctct tataggtgga tggatttatg gaaaacgttt
    17041 tgaaaaatat ccagcttatg ctattgatga gaatgataga gaaaaaaatt tagagcaggg
    17101 aaaagatagc ataaaaattg aagatgatga ttcttctaaa gtaccaggtt ttggaatttc
    17161 tatgttttct ttattgttcc caatacttct tatacttata tcaaatgtat ttagtatgtt
    17221 cttagaaaaa ggttctacaa tgagtggagt acttgcattt ataggagata aaaacatagc
    17281 aatacttctt ggaatattgg tggcaatagg atttttaaag aaatacataa ataaacctat
    17341 gggagatgta gttattgaag ctgctgattc agcagggcta atattattga taacagggtc
    17401 aggtggtgcg tttggcagtg ttataaatgc aagtggtata ggtaacttct tagttgatac
    17461 tatgtctggt cttagtatat cagttgtagt acttggattc ttattaagtg ccttgcttag
    17521 aatttctcaa ggttctgcta ctgtagcctt agtaacaaca tcatcaattt taggacctac
    17581 aattttggca actggaatgt caccagtttt agtagggctt gctatatgtg ctggaggagt
    17641 tggtttctcc cttccaaatg attctggatt ctgggtactt tcaagattta gtggattatc
    17701 agttaaagat actttaaact cttggacaat tggaggaacc attgctggag ttgtagcatt
    17761 tataatggtt ttattgctta gtgttataaa tggaattata ccacttccag gtctataaat
    17821 aacaaactat tgtttatatc atataaatta tatttagact atacaaatta cataaagggg
    17881 cgttttaaat gagagaagta aaaccaatta gcatagatat acttaatact tttaaacaag
    17941 tagatgagga tagattaaat aaacttcttg cagatgagct taagcattta gatagaaaaa
    18001 ttgttgtatt agatgatgac ccaacaggtg tacaaacagt tcatgatatt tctgtttata
    18061 ctgattggga taaggatagt atggaacaag gctttaatga gaaaaatagt atgtttttta
    18121 tacttaccaa ttcaagggga tttactgttg ctcaaactac aaaagcacat aaagaaattt
    18181 caaagaatat tgtggatgta tcaaagaaag ttaataagga ttttataatc ataagtcgta
    18241 gtgattctac tatgagagga cattatcctc ttgaaactaa tttattaaaa agcgaagtag
    18301 agagattatc ggggaagtta tttcagggtg aaataataat gccatttttt aaagaaggtg
    18361 gtaggtttac tatagataat gtacattatg ttaaagaagg agaaatactt gtaccagcag
    18421 gaatgactga atttgcaaaa gataaatctt ttggatataa atcatctgat ataggtgagt
    18481 ggtgtgaaga aaagacaaat ggaaagtaca aatctagtga tatgatatat atttcgtcaa
    18541 aagaacttag agagctaaat attgaagcta taacagaaaa acttaaaaaa gctgaaggat
    18601 tcaataaaat tattgtaaat gcaaccgatt atgtagatgt aaaggtattt acaattgcgt
    18661 ttatacgagc agtaaatggt ggtaaggaat ttatgtttag aagcgctgct gccataacaa
    18721 aagtacttgg cggagtgagt gacaaggaac tacttactaa ggatgaatta gtatcaaaag
    18781 gtaataccaa tggaggaatt atacttgttg gttcacatgt gaataagact acccaacagt
    18841 tagaagaact taaaaattgt aaatatccga tagaatttat agaatttaat caacatttag
    18901 ttcttcaaga aaatggtcta aaaaatgagg taaaaagagt tataaaagtt gtagaggaaa
    18961 aaataagcag tggtaaaact gttgctgttt atactagacg agagcgtttt gacttggata
    19021 cgaatgataa agataaacag cttatgattt ctgtagaaat atcagatgca gttaccagta
    19081 taattggtat gcttaatgta agaccaaatt ttattatagc taagggtgga attacttcta
    19141 gtgatgttgg tactaaagca ctaagagtaa aaaaagctac agtaatggga cagataaaac
    19201 ctggtatacc agtatggatg acaggcaaag aaagcaaatt tcctaatatg ccatatataa
    19261 ttttccctgg aaatgtggga gagattagca cacttagaga atcagttgag atattgatgg
    19321 ggtagtatat tagtgtattg aagtttaaac gcttaaattt actgagttaa aattaaaata
    19381 aactaaaatt ataaattaag attaaaaata atagtatatt aattagggtt tagagtattt
    19441 tacaaaaaat attctaaacc ttaatcttat gtattagtat ttttattatt taacttatgt
    19501 gtttatttta ttatttatct tttttaattg atttaatatt ttctttgatt ttatttaaaa
    19561 tatctgtatg cttattagag cttatgttgg ggaatgcttt gattatacgt ctatgaagta
    19621 atttgtggtt agacagcaaa gtattaagtt tattttttag ctcatcaata cgatttttag
    19681 catagcgata attttctttt tctttaagta tttcaaacct atcttccaaa gtatccagtc
    19741 tattttcaac taaagattca agtttgtttt ctatagtttc ttgtgtaata agtttgtagt
    19801 attctttctt atcttttaat tccttaatta taagattgat ttgttttaac ttaccattta
    19861 attgtaaaat tgtatggact gtgataacta aatctaaaac aaaataaatt tctatagata
    19921 tagcaaatat aaatagcaca tttttagaga tagagttaat aaagtcaacc acaataggat
    19981 gtactataag cattacaatc aatgataata caccaaacat aagtgagttt tccagacaaa
    20041 ctcttccatg aatattaaat ttatgtttag aataatccca ccaagtcata ttaaatattt
    20101 tttctaaaat aaagctcgta cagtactcca ttatgctagt tataattata ctaaacaaaa
    20161 ataacaaagg aatattgtgt acaaaaggag tcaaggtagc aactattgct aatgctccaa
    20221 atccatatat agggcaaaat ggaccattta aaaaacctct atttacaaat tgtttttgta
    20281 aaactgaaca atatgtagtt tcacaacacc atcctataaa gctataaatt acaaaataaa
    20341 gaaattgaat ataaaatgta ctcataagca cctcatttct agttagtata acactatata
    20401 ctcgatattt tatttttatg attaatttac taaattcaat ttacatattg attataccaa
    20461 tttatagaaa tttatcaaat ttaattacag ttagaacatt ataaacatgg ttataataat
    20521 gaaattttat ttaaaataaa taagggtgtc aagtataatc aaactaatag ttgtagatac
    20581 tctacactat gttagtttaa ttacatttga cacccttata tttatactat gactatttac
    20641 attcgaaact agagcaacat gtttcaatat aaaggtttac tctatcagtt tcaggagcaa
    20701 ccaatatatt atcaagtgta cataagctac catctttgtt gtatttacaa ttttttacag
    20761 tacaaactaa ttcctcacaa tttttattat taacgttgct agataaatta ctataaatag
    20821 attcatctaa aaatgaacta caacaagtat gtctgtcatt gtgagctttt tcaccattta
    20881 taaaaatttt atctgcataa catatatggc tgttgttatg tgaacagtta attacattac
    20941 agtttattct ttccaaagtt attacctcct aaacgattat ttattataaa ttatgtccat
    21001 ataattacaa gaatataacc attaagagaa aactaccttt tagaaaatat ctattcttag
    21061 agtaatttga aatataaata tattttcttc taaaatttac ctaaattgta taaaaactta
    21121 cagcttggag aaaataatag aaaaaggagg cgtaatcaat gtttgaaaag aagaaaaaag
    21181 aattatttcc ttggaaaata tctgccttaa tactggttgg agtatttgta ttaagtagcg
    21241 gagtttatat agggacaaga ttaaaacaca atggagttca aactggtgaa gttgtaagta
    21301 ctagtgcgaa tatgaatgaa aagtcaaaag aagcttttgg attaaataaa aattgtgaag
    21361 tttggcttca aagtgaaggc gaaaatgaaa ctaactataa gagaacactt acaatggcag
    21421 gaatagttcc agagtcatta ttagataaga cgaagtcaga aatagtatca tattttaaaa
    21481 aagaatatcc aactaaaaaa ataaagagta tggataaaaa tgaaatcata ttggtagaat
    21541 ctaaatatag tgataataaa gatgtacaag caatggatgt tactataaaa ggtaaatata
    21601 ctattgaaaa tgataatgga aatatagcac tatataaata tgatgatagc ggaagtaaaa
    21661 cattagtaga aaaaacaaaa ataagagtag attcacttcc taaaacagtt caagatgaaa
    21721 tcaaaaaagg tgtagttatg gatactgaag aagaggccta ttcaagatta gaagactttg
    21781 caagttaata gtaaattaat attattttaa gttaaatact aagtaaatta ataataaata
    21841 atttaatatt aaatagatta gtattaaaat tgtagtcaca tttaattcct ataaaaatac
    21901 aataatttat ttgtaataaa tataaaagtt atattgaggt aaaatcttgc tttgatataa
    21961 cttttttatt tgattttata ttttacatag agcattttat gatttgttaa tattatttat
    22021 gatataatga tttagaacat aagtttttat gagaaataca ttttggtatt tcttttattt
    22081 ttagggggaa ttttaaaaaa tgataatatt ggggattgac ccaggtatag ccatagttgg
    22141 atatggtata attgaataca aaaatagcaa gtttaaagca atcgattatg gagcagttac
    22201 aacacctgcc catatgaata tatcgagaag attggaactt gtgtataaag gaattgatac
    22261 aatagtaaag aattacaata tagatgaagt tggaatggaa gaattattct ttaacaagaa
    22321 tgtaaaaaca gctataacag ttgcacaagc tagaggtgtt actatgcttg catgtgctca
    22381 taatgggaag cctgtatatg aatacactcc acttcaagta aaacaaggtg tagttggata
    22441 tgggagagca gataaggcac aagttcaaca gatggtaact tcatttttaa gtctaaaaaa
    22501 agttccaaaa ccagatgatg ttgcagatgc tttagctgtg gctatttgcc atgctcattc
    22561 aaacaaactt gaaaaaactc taaagaatat aggtggtaag tatgtatagt tatataaaag
    22621 gtacagtaga agaaatttat atagacagta tagttgttga aaataatggg ataggatata
    22681 aaataaatgt atcatccaat acaataatga atttacaagt gggagaagcc acaaaaatat
    22741 atactaaatt aattgtaaga gaagatgata tgagtctttg tggttttgta agtagggaag
    22801 aacttaagat gtttgaatta ctaacatctg tatctaaaat aggacctaag gtggcgcttt
    22861 caatactatc atttgcatca ccagcacagt taggagcata tattttaagt gaagacattg
    22921 gaaaattatc caaagctcct ggtgttggta aaaagacagc agaaagaatc gtcttagagc
    22981 ttaaggataa ggtagacaaa aataacatag agtttgaacc aacgttatta tcacaaaaac
    23041 ctaccttgat atcacaagat gagtctgtag atgcacttgt agctttaggc tatactttgt
    23101 cggaatcaaa agaggcagtt caaaaatgta aaaaagatgg tatgaataca gaagctatta
    23161 taaagaaagc acttacatat ataatgagta aatccttgaa atagtatttg gattttataa
    23221 tatttggatt ttaaaacaat atttaaggag tttatgtaaa tttgaaaata tataaagtag
    23281 attttcaaaa gtacgagagg aggggtataa atgcaaggtt ttgaagatga aaataggata
    23341 ataacttcta caatgaagat ggaagatata gatatagaaa acagtttaag accaaaaact
    23401 ttagaagatt atttgggtca agaaaaatcc aaagaacaac ttagtatatt tatagaagca
    23461 gctaaatcga gaaatgagca gttagaccat gtgcttttat atggaccacc aggtcttgga
    23521 aaaactacac tagcaagtat aatagccaat gagatggggg taaatttaag aattacgtca
    23581 ggacctgcaa tagaaagagc tggagatttg gcagccatac ttacgaattt aaatgaaaat
    23641 gatgttttat ttatagatga gattcataga atcaatagaa gtgttgaaga agttttatat
    23701 ccagcaatgg aggatttttg cctagatata ataataggga aagggccatc tgctagaagc
    23761 ataagacttg accttcctaa atttacactt attggagcta ctacaagagc tggtatgctt
    23821 acaaatccac ttagagatag atttggtgtt atttgtaaat tggactatta tacagttgat
    23881 gaactttcaa aaatagtact taggtcttca agcatcttag atgcagagat acagtctaat
    23941 ggagcattag aacttgcaaa acgttcaaga gggactccaa ggatagcaaa tagattacta
    24001 aaaagagtta gagattttgc acaagtcaga gctgatggaa aaataactga taaagtggca
    24061 aaagatgctc tggaactttt aggagtcgat agtttgggtc tcgattttgt agatgagaag
    24121 cttcttatga ctataataga aaaatttaga ggaggaccag tgggtttaga tacattggca
    24181 gcttctatcg gagaagatag aaatacaata gaagatgtat atgagccata tttgcttcaa
    24241 ttaggattta taaatagagg tcctagagga agagtagcta tgccattagc atatgaacac
    24301 ttaaaaattc catatcccaa tgaaaaataa aaatagatta tacgagtatt tataaaataa
    24361 aagagtcatt aaattaaaat atttctaaaa tggctaaaaa ttcaaacata tccacaaaat
    24421 ggtaattata tctgtagata ctgtggataa acacgataaa aattgtgtgt attgtatcta
    24481 tatattgtgg ataaggcatg tatatcgtgg aaaaatatct atatattgtg gatatggtgt
    24541 ctgttaaaaa tagcaatttc ttgatagatt atggtaatat tgtggaaaat aagttgtttt
    24601 tttgatatta ttgtagctgg agaaatttta agagaggaag tttaacattg aaaacaagtg
    24661 attttaaatt tgacttacca caggaactta tagctcaagt tcctatagaa gatagagcta
    24721 gctcaagatt gatggtatta gataaagaga caggtaatat tgaacataaa gtatttagag
    24781 atataataga atatttaaat ccaggagatt gcttagtatt aaataatact agagttatac
    24841 cagctagatt aataggagag aagcttgaaa ctggaggtaa aatagagttt ttattattaa
    24901 aaagaacaga ggaagatact tggcaggctt tagtaaaacc aggaaaaaga gcaaaagtag
    24961 ggactaaatt ttcttttgga aatggaaagc taattggaga agttgtagat ttatcagatg
    25021 aaggttcaag aattataaaa ttccattatg atggaatttt tgaagaaata ttggatgaac
    25081 ttggaaatat gccactacct ccatatatca ctgctagact agatgaaaaa gaaagatacc
    25141 agactgttta ttcaaagcat aatggttcag cagcagcacc tacagcagga ttacatttta
    25201 cagaagaatt gttaaataaa ataaaagaaa aaggtgtaga tatagccttt gtaactctac
    25261 atgttggctt aggaactttt agaccagtaa aagtagagga tgttttaaat cacaagatgc
    25321 attcagaata ttatatggtt agccaagaag cagctgacaa aataaataga gcaaaggaaa
    25381 atggaaaaaa tgtaatatgt gttggtacta ctagttgtag aactatagaa tcagcttgta
    25441 atgaggatgg aaagatgaaa gaaactagtg gatggacaga aatatttata tatccaggtt
    25501 ataaatttaa agttttagat aaacttatta ctaattttca cttaccagag tctacactaa
    25561 taatgttagt aagtgctatt tgtggaaagg ataatgtttt aaatgcatat aatgaggcag
    25621 taaaagaaag atatagattc ttcagttttg gagatgctat gattataaag tagggaggta
    25681 atagatgcat agtttacaaa aacaaaaaaa gaataaccct atattaaaga ttgcttttat
    25741 atttgaacgt gttttagcag tagtagttct aatagcagta tttttaggaa ctatagatgt
    25801 tctaagactt atgtggggag catatatagt tgattttcaa aatccagtac aatacagtca
    25861 gcttaatgat tttttagcac aaatattact tttagtaata ggtgttgaac ttgtagtaat
    25921 gctatctctt catataccag gagcatttat tgaggcatta ctttacgcaa ttgctagaaa
    25981 aatgttgcta ctgcctaaaa atgaaggtat gatagatgtt ttaataggag ttatagctat
    26041 agcaggacta tttgctataa aaaagttttt agtaacaaaa gacaagagtg ctcttaatat
    26101 aatgagtatt catgatgaag aagcaattaa ggaacaacag aacaaagaag acgaagataa
    26161 atctatttag acaataaatt atatgaatag cttattacaa atatatctta agaaataatg
    26221 agaaataaat atgattaagg agaactttat gtacgcagta agatacgaat tgataaagac
    26281 ttgtaagcag agtggtgcaa ggttaggaag attacacact ccacatggga ttattgaaac
    26341 accaatattc atgccagttg gaactcaagc aactgtaaaa tctatgacac cagaagaatt
    26401 aaaagagatt ggttcacaaa taatacttag taacacatac catttatata tgagaccagg
    26461 tcatgaactt ataaaaagag ctggtggtct tcataagttt atgaattggg ataaaccaat
    26521 acttacagat agtggagggt tccaggtatt tagtctaggg cctttaagaa agataaaaga
    26581 agaaggtgta gaatttaggt cacacttaga tggttcaaaa cattttctaa ctccagaaaa
    26641 agctatggaa atacaaaatg cattgggttc agacataatg atggcatttg atgagtgtgc
    26701 accataccca tcagatagag aatatgtaaa aaattcttta gaaagaacaa caagatggtt
    26761 aaaaagatgt aaagatgccc ataataatac cgacaagcaa gctttatttg gtataataca
    26821 aggtgggatg tataaagact taagggaaca atcagcgaaa gaaataacta atattgattt
    26881 accaggatat gctattggtg gacttagtgt tggagaacca aaaccactta tgtatgacgt
    26941 gttagagcat acaactccac ttatgccaaa ggataaacca agatacctaa tgggagttgg
    27001 tagtccagat gacttagtag aaggtgttat aagaggagta gacatgtttg attgtgtcct
    27061 acctactcgt atcgctagaa atggaactgc aatgactagc caaggtaaag tagtagttag
    27121 aaatgcaact tatgctgaag actttactcc acttgaccct gaatgtgatt gttatgcttg
    27181 taaaaactat tcaagagctt atataagaca ccttataaaa gcaaatgaaa tactgggtgc
    27241 aagattaata actactcata atcttcactt tttattaaat ttaatgaaac aaataagaca
    27301 agcgataatg gaagatagat tacttgattt tagaaatgaa ttttttgcaa aatatggata
    27361 tgaaatatag gttttgcact attaattata atcattttaa tatataatat tcaatagtac
    27421 tcaaagatag agaaagtaaa ttgttatata aacatttatt atgatttaca aaagagtata
    27481 atttacaaag gagtgaaaaa ttaatgccac agcaacaaat aattatgagt ataggtctat
    27541 gggtagtagt aatcgcaatc ttttatttcc taatgattag acctcaaaag aaaaaagaca
    27601 aacaattaaa agaaatgaga agtagcctaa gtgtaggaga caaggtcatt acaataggtg
    27661 gaatagtagc taatgtagct aaagttgaag atgatgttgt aatattagaa ttaggaccaa
    27721 atagaactaa agttccattt gaaaaatggg ctataggaac tgttaaatct aaaaaagaag
    27781 aaatagaaga agactaaatt agtaatttaa aagccttttc tcgaatatat attaatttga
    27841 gaggaggttt ttttatggga aaatctaatt atatttttaa aggtctagga tatgcatata
    27901 taataacttt ggctgtttta ttagtgtata acttattttt gacatttaca gatattggtg
    27961 gagataatat aactatggtc tcatcattta taactactat ttctgcagct ataggagggt
    28021 tttacacttc aaaacacatg aaagaaaaag gacttatgta tgggctttta gtaggacttt
    28081 tgtacatagt atgtattttt ttgactgtgt ttttagcaca agaaaagttt gtatttgaag
    28141 tagggatgat ttataagtta ttgttaatat cagcagcagg aggcattgga ggcgtattgg
    28201 gtgtcaactt taaatagagt ttatattaaa gtagttttat gatataatca ataggaaaca
    28261 attagaaatg gaggcgttga aaatggaaaa taaacatgta aaaactttat ctcaagctac
    28321 tttaaagcaa agtgctgcaa aaggtggatg tggagagtgt caaacttctt gtcaatcagc
    28381 ttgtaaaact tcttgtacag ttgcaaatca agagtgtgaa agatagaaaa ttattgattt
    28441 agttgtttgt aagagggtat ctcaaagtga ttcttttatc attatgaggt atcctctttt
    28501 attttcaatt attatataaa aatatatatt ctatttatgt aaaattaaat ttgatttctt
    28561 atcgtttaat tatgcaaaaa tatctaatca tataagagca ttta
//
LOCUS       DAMJWC010000052        25773 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMJWC010000052 DAMJWC010000000
VERSION     DAMJWC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25773
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.052"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(78..1106)
                     /locus_tag="PC503_002590"
     CDS             complement(78..1106)
                     /locus_tag="PC503_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2528556.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVVYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(1154..2014)
                     /locus_tag="PC503_002591"
     CDS             complement(1154..2014)
                     /locus_tag="PC503_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2528557.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2283..2492
                     /locus_tag="PC503_002592"
     CDS             2283..2492
                     /locus_tag="PC503_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2528558.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2492..2758
                     /locus_tag="PC503_002593"
     CDS             2492..2758
                     /locus_tag="PC503_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2528559.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2787..3359
                     /locus_tag="PC503_002594"
     CDS             2787..3359
                     /locus_tag="PC503_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2528560.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3594..4784)
                     /locus_tag="PC503_002595"
     CDS             complement(3594..4784)
                     /locus_tag="PC503_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2528561.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(5044..5475)
                     /gene="dut"
                     /locus_tag="PC503_002596"
     CDS             complement(5044..5475)
                     /gene="dut"
                     /locus_tag="PC503_002596"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF2528562.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5588..7816
                     /locus_tag="PC503_002597"
     CDS             5588..7816
                     /locus_tag="PC503_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF2528563.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7927..8412)
                     /locus_tag="PC503_002598"
     CDS             complement(7927..8412)
                     /locus_tag="PC503_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2528564.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8664..9887
                     /locus_tag="PC503_002599"
     CDS             8664..9887
                     /locus_tag="PC503_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2528565.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPSILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9891..13025
                     /locus_tag="PC503_002600"
     CDS             9891..13025
                     /locus_tag="PC503_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF2528566.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            13059..14357
                     /locus_tag="PC503_002601"
     CDS             13059..14357
                     /locus_tag="PC503_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF2528567.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLTDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14646..14891)
                     /locus_tag="PC503_002602"
     CDS             complement(14646..14891)
                     /locus_tag="PC503_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2528568.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(15105..17732)
                     /locus_tag="PC503_002603"
     CDS             complement(15105..17732)
                     /locus_tag="PC503_002603"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2528569.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17793..18635)
                     /locus_tag="PC503_002604"
     CDS             complement(17793..18635)
                     /locus_tag="PC503_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF2528570.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18642..19280)
                     /locus_tag="PC503_002605"
     CDS             complement(18642..19280)
                     /locus_tag="PC503_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528571.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19716..21008)
                     /locus_tag="PC503_002606"
     CDS             complement(19716..21008)
                     /locus_tag="PC503_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2528572.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDIDLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(21045..21401)
                     /locus_tag="PC503_002607"
     CDS             complement(21045..21401)
                     /locus_tag="PC503_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2528573.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21436..21795)
                     /locus_tag="PC503_002608"
     CDS             complement(21436..21795)
                     /locus_tag="PC503_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528574.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21864..23837)
                     /locus_tag="PC503_002609"
     CDS             complement(21864..23837)
                     /locus_tag="PC503_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2528575.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSINEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(24059..25072)
                     /locus_tag="PC503_002610"
     CDS             complement(24059..25072)
                     /locus_tag="PC503_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2528576.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(25085..25630)
                     /locus_tag="PC503_002611"
     CDS             complement(25085..25630)
                     /locus_tag="PC503_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2528577.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8814 a         4282 c         3274 g         9403 t
ORIGIN      
        1 taatttaatt ttatcttgat tcagttttat aaaaaattgt tataattgtc aagttctact
       61 ctattattta taatttctta tatcttatta acaacattta ggttattaca tttatttata
      121 tatatttttt cattatctaa gtcttcatca aacattttta ttatattttt tatctcatac
      181 ttgtactcat cttcattcat tctataaagc attaaatctt ctagtacatc tttcatgtcg
      241 aagtacacat cttctaataa ataaaaatag ccttcctcta tatctttcaa tttatctata
      301 gtatccattt ttttacttat atctttcata atttctaaat tttgtatatt tacatctatg
      361 attgttaata agtacattct cacagttttt attatttcaa cagaaaaatc tacaatatta
      421 taatttcctt cttttttata taatgactcc ttaaatttgt taaaacaatt atctaaatta
      481 gaatttatat cgttaaatgg tggtcttatt atgtcacgta ttattaaaag attttgtata
      541 tctacattat ttgtgattgc ctcatccaaa ataaataaat tatatgcatc atttaatggg
      601 tcatgggcat ctccactaaa ctctaagtta acaaattcaa gtaaattttt caatgatata
      661 tagttcatac atctcatacc acaatttata tatttttctt ttatatctac aaataaatct
      721 ctaatgttat ttacaaacct tggatggtta ttttttttag cacttctcat atctgtgtta
      781 ttgaaacatg tcaaatccaa attaccaaaa gtatatattc ctttaatatc agaaaatatg
      841 ccaagccatt ttttaaactt tctcatgacc tcttcataac ttggtgcact cttcaattct
      901 tcagaagata tatgtgttaa ttcttgtata tgaggataca actcctcatt acttactggt
      961 cttattaaag atttaaattt atcaatattt tttgtttttt catcatacac aactgctcca
     1021 attgcaatta tatcagaatt aaatactgct ctttttgatt tagaatttgg catattcatt
     1081 tcaaaatcta tatatactct tttcaatata aacacccttt ccaattgttt atagtgattc
     1141 tttttaacta tttttattca aaattttcta agaaagaatg tttctcccca tctttttgcc
     1201 aaccaagtac tgaatcaaga tttacatttt ctgccgcctt aaatatagat ttttctacat
     1261 ttttaaaatt tgattctaaa ctctttatta agtcttttat ctcatatctt ttattacctg
     1321 tttttttagc agcaaccata catgcacaat ttaatggcca tataccacta ttttgaataa
     1381 atcttataat atgttcttct cttatataat aaagtggtct tataattttt ataccttcaa
     1441 aattagtaga attaagttta ggaagcattg ttttaaaatt tccagcacac aataagttaa
     1501 gcattgttgt ctctattaca tcgtcataat gatgacctaa tgcaagtttg ttgcacccta
     1561 gttcttctgc ctttgaatat aatgctcctc tcctcattct tgcacacata tagcatggat
     1621 aatcttttgc tatttcatct gctatctcaa atatccttga atcaaataaa tgtattggta
     1681 tatttagata ctcacaatta tctataagta attgtcttat atttgcatga tatccagggt
     1741 ccatagcaat aaattcaaca tcaaaattaa cttgtccatg tttttttaac tcttgaaaca
     1801 ttttagccat aagaatactg tcttttccac cagaaatcgc tacagctatc ttatcacctt
     1861 cttcaaccaa tttataatct cttattgcct tcataaactt agaccataaa ttttttctat
     1921 atttttttat tatacttttt tctatatctc ttactggaag tctttcctca aaaggaacta
     1981 taatttcaca gccttttcct gatagttcac tcatctaatc acctcgtata tttatgttaa
     2041 taatatttta caaaaaagtc taccttcatc cacaaaatac tataattttt actttaattt
     2101 tactaaataa tttatagttt acaataacac ataaacttat aataacataa ataacctctt
     2161 tcttttatta tcttttttat ttttctcatt taatatttta ttattagtaa cgatttttaa
     2221 atgattgaat attatacact agatagagtt acctatctat ttacaacaag gaggttttca
     2281 tcttggaaaa taagactaga gatatcaaaa aaaattgtgg tccatctttg gctagaccat
     2341 acattaataa tcaaattttc acagaaatgt actgcctttc tgatgcatta aaatttggaa
     2401 ctatatttcc agaactaaac ttactagagt ctgaaatgta caacaaagaa ttatatgcta
     2461 agccaaaaaa atatagagga ggtagaagat aatgaaagac tcatctagag ctgaacttat
     2521 gagaaaagtt caggaaacat cttttgcatg tgttgatatg aacttatatt tagacaatca
     2581 ccctgatgat aaaaatgcta tcaacactta taattcatta tgtaatcaat ttgcgcaagc
     2641 tagatatgct tacgaaaata aatacggtcc tttaactaac tttgggtatg ctccaagtag
     2701 atgcccttgg caatgggctg accaaccttg gccttgggac agagaattta attattagac
     2761 atcaagtatt ggaggattga aaattcatgt ggatatatca gaaaactata caacacccag
     2821 ttaatataaa aacttgtgac cctagaatgg ctaaatttct tataactcaa tttggtgggc
     2881 caaatggaga acttgctgca tctttaagat atttaagcca aagatataca atgcctactg
     2941 gtaatatgcg tgcactttta acagatattg gtacagaaga actagctcac gttgagctta
     3001 tatgtactat ggtttatcag ttaacttctg atgcaagccc agaagagtta aaagctgcag
     3061 gtcttggttc aaactatgct caaaatggat atggaattta tccaacagat tcaaatggtg
     3121 ttccatttga tgtaagacct atagcagtta tgtcaaatcc cgtaaccgat ttacatgagg
     3181 atatggcagc tgaacaaaaa gcacttgcaa cttattatca acttataaac ctaacagatg
     3241 acgttgatgt tatagatgta ttaaaattct tgggtcaaag agaaataatt cactatcaaa
     3301 gatttggtga agctttaatg gatgcttacg agttagaaga atctcaaaaa atgttctaaa
     3361 atttttattt gtataactat tattatttga taatttataa tttactgttg tgttaaaatt
     3421 tataaaaaat ataaatataa tttattttct ataaacagag aaaataaata aaaagcaggt
     3481 atcaatcaaa tagtaacatg tattatacta tacattacta tcaatattgt acctgctttc
     3541 atattataag caataaagaa aaatctattt attaggtttt ataataaaaa caattataaa
     3601 actcttcttg catttacata tctacttgaa tagtagctac tatttatatt agatattgtt
     3661 actttttttg atgaacctga agatgcatgt atcatatctc catttcctat gtatattcca
     3721 acatgactta cagaaccatt atttgaacct tgtgtatcaa agaatactaa atctccactt
     3781 ctaaggtctc ctctatttac atatgttcca tacttacttt ggtctctaga tactcttggt
     3841 atactaactc ctacagattt tttcataacg tactgtgtga atccagaaca gtcaaaacta
     3901 tttggacctt ctgctcccca tacatatggt tttccaagta gtgtctttgc aaaacttatt
     3961 acactatcag ctccttgact tggagaatta gtcgaataag atggaattga agtatcaaca
     4021 gaaccttttt cagcaaggta ttgacttgac acatatccag tttgattgcc ataacttact
     4081 tttgtccatc ctccactttc agaaatactt ccaacctcag taccataact taatgtagct
     4141 attttagaat gacttgtacc tggtcctgtt ctaacgttca atgactttgc tgttacaacc
     4201 tttgtaccct ttacaaggtc atttgaactg ttttcagcat tttcatttgt agagtcattt
     4261 acactagttc ctaaatattt acttgaaaca taacctactc taccattaga acttattttt
     4321 gaccatccat ttgactcaga tatgtatccg acttcagtcc catatcctag tgttgatatt
     4381 ttagaactac ttgtacttgg tcctgttcta aaatttaatc cttttgctgt tacaactttt
     4441 gtcgacttaa ctgaagtatc actactttca ttgctacttc caaggctatt tattgctaca
     4501 taatttccat gcacataacc tgtgtttcca ttatatttaa cttttaccca agaaccttct
     4561 tttcctacgt actcaacttt atcacctttg taaagtttcc ccattgattc atggtttgta
     4621 cctggtcctt ttctaaaatt taccgcattc cctgttattg ttctgctttc tatactcaca
     4681 ctctctactt cagactcatt agcatatgct aaattcccca tagtaggcat tattatcgca
     4741 gttgccatta tactggctgc tattctcttt tgattaaaat tcataacttt ccactcatct
     4801 cctcttttct actatcttta tttcacttca aaatataaaa gaaataattg acactattaa
     4861 aatatcaatt atttctttta tattaatatt attacaaatt tgtaactatt tgtctatagt
     4921 aatatttgct taccataaat taccatgtat aaattttaat ctttaatagc ctgtaattta
     4981 gtaatatagc catcttttac cttttttaaa aatggctata ttttttaact tttttgtaac
     5041 tttttaaaat ccagttgagc caaacccacc ttttcctctt tcggagtcac ttaattcttt
     5101 tacttcttct atgttaatat catagatagg ttttactatc atttgagcaa ttttcatatg
     5161 cttttcaacc ttaaaatcat ttttaccatg atttattaat ataattttaa gctctcctct
     5221 gtatccttcg tcaatagttc ctggtgtatt taatacagta acagaatgct ttaaggcaag
     5281 cccacttcta ggtcttacct gcgcttctgt catagtagga agctctatac atatcccagt
     5341 tttgataagt ttagtctctc caggaggtat tacaacctct tctatagaat acaaatccat
     5401 accagcatca cctttgtgag caaaattagg tattatagca tcatcattta atttttttac
     5461 ttttaaattg tacatcttat atctcctttc aactttctat aaatattata acttaaattt
     5521 cgacctcttg aagtttttta tttttttgtg gtaatataat tattagtgtt ttaaaggagg
     5581 attttttatg aaacttgtac ttgctgagaa accatctgtg gcaaaaacta tagcatcatt
     5641 tttaggtgca aagaccagac aagatggtta ctttgaagga aatgattata taattactta
     5701 tgcagttgga cacttagtat cattatatga tatgaaggat tatgataaag ataaatactc
     5761 tggctcttgg aaaatgaaca atttcccatt tgttcctgag gataagttta aatttaagat
     5821 tgatagttct aaaactaaac aattcaacac tgtaaaaaag cttttgaata gaaaagatgt
     5881 agaatatgta ataaatgcca ctgacaatga ccgagaagga gaacttatag catttttaat
     5941 atttttactg gcaaaaaata aaaaaccagt aaaaagaatc ttggtaaatg aatggacacc
     6001 agaagatatt acaagaggta taaaaaacct aaaagatgaa gatgaaatga gaaatcttca
     6061 agctgctgga tatactaggc ttattactga ctggttgatt ggaataaatt tcacttctgt
     6121 tgctacattg aaatatggaa atgggaaact attaaacata ggtagggtaa ttcttccaac
     6181 agttaaatta gtctatgata gagatatgga aatactaaac tttgttccta aaacctatta
     6241 tgaaatagaa gggcatttta aagctgaagc tggtgaatat aaaggtaaat atgttaaggg
     6301 taaagaaagt aaatttgata cacttgaaga tgcaaataaa attatagctt caattacatc
     6361 tgaaactggt aaaatactag ataaaaaagt tactatgtca aaggaatatg caccaaaact
     6421 ttttagtttg acatcacttc aaggatatat aacttctaag tattccaatt ttacatctga
     6481 taaggtttta aatgtctgtc aatctctcta tgagggtaat ggtaagggtg gatacataac
     6541 ttaccctaga actgattcca ttttcttaga agaaagtttg gcttcaaaag cttctcaaac
     6601 tttagataaa ttaaaggttg gtcttgaata tgaaaataaa attaaatttt ctaaaactaa
     6661 aagagttttt gattcttcta aagtagactc ccatagtgct ataattccaa cttatataat
     6721 tccaaaaagt ttatctaagg atgaacaatt agtttatgat gccataaaag atagatttgt
     6781 agcaaacttt atgcctcctg ctgaatatga gaatacagaa attaagactg aagtagataa
     6841 ttgtactttc ttaacaaaag gtaaggtgct taaatcaaaa ggataccttg aggtatataa
     6901 taaggaagaa aaaaacgatt tacttccact tgtaaataaa gatgatgttg tagatgtgtt
     6961 agaaataaaa ccattaacta agcaaactac tccacctaaa ccatatactg aggacacact
     7021 tttaaaggct atgaaaaatt gtggtaaaaa tgtgcctgaa gaagatacaa cagtgctatc
     7081 tggatattcg attggaacat cagccacacg tgctgatgtg ttaaagaaga taagtcaagt
     7141 gggctatgta aagaaaaaag gtaaatctta ttctataaca gaccttggga aaaatttagt
     7201 tgaaattttt cctgttaaag acttatttga tgtagattat actggaaaac ttgaaaaaag
     7261 tttaagcgat attcaaaaag gaaagtatac aagaaaagaa tatcttacta atatcattag
     7321 ttttatatat caaaatgtca atattataaa acaagatgct tcaaaaaata taaacacaga
     7381 agcatatact ttcgattcaa aaactaaaaa atttactaaa acaaaagaaa aaaaacagaa
     7441 aaaagatgta actaatactg aaaaagaagt tgctatatca aaggattcta ataacaaaaa
     7501 agaagttaaa aatggtgatg aaaatcaatc tcttggcaaa tgccccattt gtcaaggtga
     7561 tgtactagaa tttgacaaag gctttgcttg taaaaatcat aaagaatgta aatttgttat
     7621 ttggaaaaat gataagtatt taagtcttta taaaaagaaa gttaacaaaa caatggtcaa
     7681 aaatatttta aaaaaaggtg aaactaaagt aaaatcttta actgctaaaa acggtaataa
     7741 atttgatgct acattaaaat atgataaaaa tccagatact ggctatttca attggaaaat
     7801 agagtttgac aactaaatat tcataagaaa agaaatagca gtagtataat aatctatatt
     7861 atattactgc tatttctttt cttatgaagt tttaactttt ttaatagtga cttttacaat
     7921 cacactctaa cctaatttct ttactatttc tgataacttt aatgtatgtt catctaataa
     7981 agttagttcc tcttcagaaa gattagataa tttttttact agagattctt tgagaatagc
     8041 ttttactgca tcaaataatt taaatgcttt atctgttaat tcaaccctaa gaatccttct
     8101 atcttttggg tcaggaaatt tattgactaa accatgttcc actaatctgt caataatcgg
     8161 agtcatattt gattttaaaa ttcctaaatt agaagctatt tgagaaattg atgatgaatt
     8221 tgatgtcata agataaagaa ttaccttagc atgtgatgga gccattggac attcttcaaa
     8281 ataagctttc attatatcag agttattttg aaactttttt aacaaatcgc tttctttaaa
     8341 tatattattt tcaagcacaa ataaaaaatc taaaaaagag tccgctattt taagtatatt
     8401 gttgttatcc atatttgtaa catcccttca atagataata taataaaaca ttgttgttta
     8461 atatagtata aattataaac tattaataaa tttaaaacaa gaaaaagtta ttgactcata
     8521 ataattataa atttataatc aaattagaga attataaatt gccaataaag ggaagttttt
     8581 taattagtct aaaactaaac ttaaattata agacacttta aattctacaa caagctagtg
     8641 tgcaatatat aataggagga gatatgaaaa gatatttaat agttttctta atgtgtagtt
     8701 cactgttttt agttggatgt ggaaaaacag aagaatctga acctgagaaa ccaatagcag
     8761 tttctgttca aaaagcaata ggtggagaaa ttgaaaacac aaattctttc tcaggaacta
     8821 caaaggttaa agatgaaaca gctgttactg cacagactgt tggcacagtt caagaagtgt
     8881 atgtaaaact tgggcaaaat gtaagaaaag gagatgaatt attgagtata agcagtccag
     8941 agctagaaaa tagtgtaaag caaagtaaag cctcactaga tttagcaaaa gcaagttatt
     9001 caagtgccac tggtggttca ttagaggcac aagtaaatca ggcaaaaaca gctcttgaca
     9061 atgcaaagat tcaatatgag gagtctcaaa gaaattatga caataataag attctttatg
     9121 aacaggaagt cattagttta gaccaattta aaaaaataga attttcttta gagcaaacaa
     9181 aacaacagtt agattctgct caaagagcat acgatacagc aacttcaaaa agtatacctc
     9241 aagctaaagc acttgctaaa aaacagcttg accaagctca agtatcatat aatttagcaa
     9301 tgagtaattt agacaaatta acattaacat ctccagtaga tggtacaata acagctaaaa
     9361 actttgattc aaaggaaatg ataacacaat cacaaccagc ttttattatt tctaatccta
     9421 gtatactaga agttgattta aatgtagcag aatcagatat aggtaaattt aagaaagatg
     9481 gaaatgtaga tgttataatt gaagaccaaa ggattttagg aaaaatagat tatgtacctt
     9541 cagtagttga ccctcagaca tctttatatc ctgttaaagt acttgtaaat aatacaaaca
     9601 acaaatttaa ggcaggtatg tctgctcaag taaacttaag tgttgaaaaa gaaaatggtg
     9661 ctgttacagt acctaaaaaa gcaatatttg aagaaaatgg taaaaaatat gtatacatag
     9721 caacaaaaga caatatagca aagaaacact tggttcaaac tggaattgta acagaggata
     9781 aaatagaaat taaaagtggt gtaagtgata aagatacagt gattattgga gggataagtc
     9841 ttatttctga cggaactaag atatttcctg tagaaaagga gaagtagact atgaatttaa
     9901 cacagacttc cgttaaacgt cctctcacaa tcataatggt ctttttagta ttaatagttt
     9961 ttggtggtat tggatataaa aaaatgtcaa taaatctaat gcctgatata gaaataccag
    10021 ttgtaatggt catgactact tggacaggtg ctggtcctca agacgttgat gaacaagtta
    10081 gtcaaaaagt tgatgaaagt ttatctgccg tttcaaatgt aaaatctact atatcaagtt
    10141 cacaagaaag tgtttctatg gtagttgctc agtttgaatt tggaactaat ttggatgaaa
    10201 taatgaatga tgttaggtct aaagttgatg cattacagac cagcctccca gatgatgcag
    10261 ctaaaccaac agttttaaag ctggatatga atgcacaggc cataggtcaa cttgtcatat
    10321 ctggaggaaa tgaaaatagt tcacaagcct taagaaaata cgctgaagat gtaattcagc
    10381 ctaaaataga atccatagat ggtgttactt cagcagacct taaaggtgga aaaaaagcac
    10441 aggttaatgt aatagctgac ccagctgttc tttcaaatta tggggttagt ttatccacta
    10501 taaaaggtgt cttatcctct agtaataaaa cattccctta tggttcaatt actcaaggtg
    10561 aggataaaat agttttaaga gcgattgata aattagaatc cctagatgat ataaaacaga
    10621 ttcaaattcc tgtaaaagga ggaaatacag ttagattaga taatctttgt agtgtagatt
    10681 atggatatgc agacaaagat agtatttata gatacaatgg aaaagacagt ttggtaatag
    10741 atatttctaa acaacaagat gccaacactg taaaagttat gcagagtgca tacaaatacg
    10801 tagatgaatt gaataaggaa aatcctcaat ttaaaattaa aattgctaat gatacaagtt
    10861 catacataag tgaatcaata aacagtgtaa tgagcaactt gcttataagt gctgttatcg
    10921 catttattgt aatatttgct ttcctaaaaa gtgtaagagc ttcactagtt gttgcagttg
    10981 caataccaat ttctataata ggtgctatag caattctcta ctttactggt gaaagtttaa
    11041 atcttattac tgcaagttca ttggtaattt cagttggtat ggttgttgat aatgctacag
    11101 ttgtaattga aaatatattt aaatatagga aaagtggcag attgagtctt gatgattgtg
    11161 ctattgaggg aacaagaact gtaacaaatg caatacttgc atcaacattg accacaatag
    11221 caatattctt acctatcatg tttacagaag gtatagctaa aataactttt ggggcattag
    11281 gtaaaacact aatagcttca ctagcattct cctttatagg tgcaattaca ctcgttccta
    11341 gtgtatttgc aaaattaagc agaggaaaaa atagtcaaaa gatgcaagaa aaagatagtc
    11401 ctatatttga taaggtaagt gaagcatata aaaaattatt aagtgtatgt ttgagacatc
    11461 aacgcttagt tgtaatatca agtttactta tttttgtagc ttccttattt ggaatgggat
    11521 ttataggtat ggactttatg cctgcagcag acaagggtga attatctatt tctatagaac
    11581 ttccaaaagg tcttagccta gaatccaatg attactatgt atctatgact gagaaaaaag
    11641 tctcagatat tccagaaatt aaaactttaa taacaacttt gacatcagat tcaaataata
    11701 gtaaagcaag tatagcaatt gaattagaat ctcaaaaaaa tagaaaaaga actactgatg
    11761 aaatagaaaa agagataatt gatagagtgg ctactgtacc agattgtaaa ataaatgtaa
    11821 gtcaaaacag tagtgttatg ggtggagctg gaggagcaga cttcacatta gaaatgaaag
    11881 gtcctgattt agatgtatta aaaatactgg gaaaagaagc tgaaaaagaa tttagctcta
    11941 taaaaggatt tagaaatgtt gaaacttctc ttacagatac aacacaagaa gctcaattta
    12001 ctatagataa acataaggct caagaatatg gtgtaaatac cgctgaaatt gcaggcatgt
    12061 tacgtacagc aataaatggt gactccgtaa ccactgctac tattgatgat tacaaagtgg
    12121 atgtaaacct aaaatttaaa gcagatacta ttgatagctt agaagatata aagcaactaa
    12181 aagtaaactc tgcaactgga aaagaagttc ctcttggtgc tttttcagat ataaaaatgg
    12241 cagatggtct acaatctata tctaggactg atggagattt ttctgtaaat ataactgcta
    12301 cacttgacaa tttagatgct ggtactgcta caaaactagc actagaaaaa acgaataaaa
    12361 tggtaattcc taaagattac tctataggtg ttggtggtga aacagaaatg atgaatgaat
    12421 ctatggcaag tcttggattt tcaatggtca tagctatagc attagtttat atggtaatgg
    12481 tagctcagtt tgaatcattt agtaaaccat ttataatcat gttctgtgtt ccatttgcat
    12541 tcgttggagt tgtgctttcg cttctagtta gtggtcaaag tttaagtact gtcggtatgc
    12601 taggtataat cttacttatc ggtattgttg ttaataatgg tatagttctt attgactaca
    12661 tagagcaact tagaaaaaca aatcgtaaca atgatttaat tggtttggtt tcaattggtt
    12721 gtgcagcaag attaagacca gtcttaatga ctacagcaac aacaatttta ggtatgttgc
    12781 caacagcact atctcttggt gaaggtggag aaactatgca accactagcc atagttataa
    12841 tgggtggtct aactgtatct acacttataa ctttggtgct tatacctact atatacttaa
    12901 tatttgataa atgggaaaat aagttttcag acaaaatgcc taaaatattt ggtaagataa
    12961 cagataaaat aggaagtata aaacgtaaaa taataaagaa accaaaattg aaagctaaag
    13021 tttaaataga atggagggtg attgtattga ataaaaaaat gagcaaaata gttgcaattg
    13081 gctgtggtgt tggtataata actgccaatt taatcccagt ttacgcagat aataatactt
    13141 cttctataaa caaagttgat aattctattt taagtgactc aaataaaaga acatctgaaa
    13201 aggaaatttt gactgctaga gaagctgtta gtgctgcact taaaaatagt gaaaaattaa
    13261 aaatgaaatc agaagaaata aaaatgttaa aagaaaagtt agaagtacaa gatgagtttg
    13321 atagttttac tggaagtgac aactcgtttc catacgacca aattggactt cttaaaaatc
    13381 aaagtgaaca ggctaaaggc tttatggagg accaaatagc aaatgatatt actaataaat
    13441 ttaacgattt agtttcaaga gaaaatgagc tagacaagat aaaaaacaat cttgaaataa
    13501 aaactaaaga aattaaagat atgaaattaa aaaaagattt agggttagta acatctttag
    13561 aaactgaatc agctgaactt gaacttcaaa cactacaaaa tactcaaaaa gctaaacttc
    13621 aagaactaaa aaacaatcaa gactacttta agttgttgac taatatagat ttaaataatt
    13681 atcaattgga taaagaatat agatttgaat cttttagagt aggtggctca gttgattcat
    13741 atatggaagg taaggttaat gaatatttaa aatacgacca attgatttta gaacgtacag
    13801 aagaaagctt taatgataaa gatgagaaca aagcagattt accagataga cctaatctta
    13861 caagaccagt tgctcctaca aaaccagagc aaggtaacct aactgatgat gaatataagg
    13921 ttcttacgga taagtatgaa aaagactaca agagatatga aaaagaagtt gaagcataca
    13981 atcttgaaag acagacttat gctgctggcc ttactactta tgcaaattat cttcaacaaa
    14041 aatttaatac cgaaaatggt ctagtaacat tagaagacag taaaaaagct cttaaaaaag
    14101 ggttaattga tagctatgct caattacttg ctttagaaga tacaattcag attactaaaa
    14161 aacaacttga tttatcagaa aaacaattaa aaaatactaa attaagatat gatttaggat
    14221 taattactct aactgattat aaaaaacaag tggtaagtaa tgaagatgct aaaaatagct
    14281 atgacactct tattgtgaat tataactcac taaaaaatgg tatagaaaaa ccttggatac
    14341 ttaatactgg aaaataattc tggtaaatag aaagattact ttaacatacg tttgattaaa
    14401 aaatagttat gcacactcgt ggctttagtc atggaagatt cagaaggcaa ataatagaaa
    14461 tagattagta aaaatatatt tgcttataaa actgtataat tttatagagg ctatctcaaa
    14521 atagagataa gcctcttttt tattgtttaa attataaaaa tatatttaat tccatacaaa
    14581 aagagtgcct tatgaactaa aaagttcatt ttgagacacc ctcaaaagct taactctaaa
    14641 tttaattatt ttttatcaaa tgtctcatct attttacatc tcaccatgtt aacaaattca
    14701 gaaatattat atcctctaag tttgcatcca catttaggac aataatccaa tttcctagat
    14761 accaaagccc tacaactagg ttctggacat cttattttta gactctcatc tgctacttta
    14821 aatccacatc gtgggcatat actacctgga cgtgatgata cttcctttcc acatttagga
    14881 cactttgtca actttatccc ctccagtaaa ctcaatttaa ttgatagttg aaatttctct
    14941 ctacaataat atatgcaata taattaaata cgtttcactt acaactatat aagttaaatt
    15001 tttataataa aaatccccta tattcaattt acaaatactt aatttgatac attgaacaat
    15061 aggggatttt atttttattt agttacatat tttgcagtct attattatct aggatttttt
    15121 atagatgctt gagctgctgc aagtctagca attggcactc taaatggtga acaagataca
    15181 tagttaagtc ctacactata acagaactct actgaagatg gttctcctcc atgctctcca
    15241 catattccta gttttaattc tggtttaact tctctaccta atttagctcc catcttaact
    15301 aacttaccaa caccattttg gtctagtact tggaatgggt ctttttctaa tatttcttca
    15361 tctacatatt gacctaagaa tttaccagca tcatctcttg aatatccaaa tgccatttga
    15421 gttaagtcat tagtaccaaa actgaagaag tctgcttctt gtgctatttc atcagcagtt
    15481 aaacaagctc taggtatttc tatcatagta cctacagtat aaggaacttc tataccttct
    15541 tcttttatta tagcgtcaac agtttctact atcatttttc ttattatttt taactcattt
    15601 acttctccaa ctaatggaac cattatctct ggagaaactt taacacctgc tttgattgct
    15661 tctatagcac cttgtattat agctttagat tgcattacac atatttcagg ataagttatt
    15721 gcaagtctac aacctctgtg tccaagcatt gggttaaact catctaaatc aactattctc
    15781 ttcttaatat cacttacttt tattcccata gattttgaaa gttcttctat agtctcatca
    15841 tcatgaggca aaaattcatg tagtggtggg tctagtaatc ttatattaac tggttttcca
    15901 tccataactt taaataactc tacaaaatct tctctttgca ttggtaatat tttttcaaga
    15961 gctttttctc tttgttctac tgtattagat aatatcattt ctctaactgc tggcaatcta
    16021 gcttcatcaa agaacatatg ctcagttcta catagaccta taccttctgc accaaactct
    16081 atagctgcac gagcatctct aggattatct gcattagttc taaccatcat acatttgtgt
    16141 ttgtctaccc agttcattaa tttttcaaaa tttccagtta aagatacttc tgttttctta
    16201 acatctccta ggtatacatt tcctgtagaa ccatctatag aaatgtattc tccttctttt
    16261 ataactacat catcaagtgc tcttatttct ttattaaact catcaacttt tatttctcca
    16321 catccagcaa cacaacattt acccatacct ctagcaacaa ctgctgcatg tgatgtcatt
    16381 ccacctctag ctgtaaggat tccttctgct ttaaccattc cttctatatc ttctggagat
    16441 gtctctagtc taactaaaac tactttttct cctttttcat ttgcttttac tacatcatca
    16501 gcattgaaat aaactttacc acttgctgca cctggtgatg ctggtaaacc ttttgctata
    16561 accttagctt cttttaatgc cttatcttca aattttggat gtaataattg gtctaattga
    16621 ttaggctcaa ttctcatgat agcttctttt tcatcaatta ttccagcttc aactaaatca
    16681 accgctacat ttattgctgc tgctgctgtt ctcttaccat ttctagtttg tagtatatat
    16741 aatctttcat tttctatagt aaactctata tcttgcatat ctttataatg accttcaagt
    16801 atatgagtaa tttttacaaa ttcatcgaat acagctggca ttacatctgc aagagttgat
    16861 atattttgag gagttcttat acctgcaaca acgtcttcac cttgtgcatt cattaaaaat
    16921 tcaccaaata atttattttc tcctgtagct ggatttctag taaatgcaac acctgtacca
    16981 ctagtttctc ccatattacc aaataccatt gattgaatat ttactgctgt tcctaagtta
    17041 tgagctatat cattcaattt acggtatacg attgcacgag gattattcca tgatctaaat
    17101 acagcctcta ttgcaagcat taattgctct tttgggtctt gtgggaaatc attttttatt
    17161 tcttttttat aaattgcttt aaattctttt actatttctt ttaaatcatc agttgtaagt
    17221 tctgtatcaa ctgtgtatcc ctttgcttct tttactctgt ctaatacatt ttcaaattta
    17281 tattttggaa cttccatagc aacatcagaa aacatttgta tgaatcttct gtaactatca
    17341 tatgcaaatc tttcattttg tgtagcctct gctaagccaa caacactatt gtcattaaga
    17401 cctaggttaa gaattgtatc catcattcct ggcatagaga atactgcacc agaacgaact
    17461 gatactaata atggattctt attgcatcct aatgttttat ttaagtcttt ttctaaagta
    17521 gctaaatgct cttctatttc ttttattatc tctgctctta tactttcatt gttaacataa
    17581 taatcattac atgcttctgt tgttatagtg aatccaggag ggacaggtaa gcctatctta
    17641 gtcatttctg ctaaattggc acctttacct cctagtaaag atttcatgtc tttgcttcct
    17701 tcaccaaaac tataaacata cttagtttcc attgttaaat cccccattaa tctttttatt
    17761 ttaatttata tcatttttat taatagacat tattaaattt ctatttcttt gtatatcttt
    17821 agaccatttt ctttcattat gtctaaaatt atacctgctg tttcttctat tgccttattt
    17881 gaaacgttta ttactgggca tccaattctt ttcattatct cttctgaata atctaactcc
    17941 tgaagtattc tttctaaatt agcatagttt gctttactgg acaatcctaa agcttttaat
    18001 ctttgggttc ttatctcatt cagcttttca ggtgaattag taagacctat tatcttttta
    18061 gtatctatct caaacacttc tttaggaatt ggtatttctg gaactaatgg aacattagct
    18121 acttttatat ttttattagc taaatacata ctcaaaggag ttttagatgt tcttgatatt
    18181 cccactaaaa ttatgtctgc ttgaagaaca cctctagggt cttttccatc atcatatttc
    18241 actgcaaatt ctatagcttc aactctctta aagtaagatt catctaattt tctaattata
    18301 ccagcttctc ttttaggttt tcttcctgtt ctcttgctta tttctcttag tatatctgtc
    18361 attaaatcta tacaactaag accttctctt tcgcaatatc tttcaacaat actgcataat
    18421 tcttcatcaa ctaatgtata tacaattaaa gcgttttcag cttttgcatt ctccaaagtt
    18481 tcaagtagta ctcctttatt aatcatgtat ggaaatcttt ttatttcata agtttcattc
    18541 acataaaact gagacataca tgcctttgca acttgttgtg cagtctcccc tactgaatct
    18601 gatactgcat atataattag gtttttcacc agcatacctc cttaattgtc aactatttct
    18661 aagaatagct tagttatgtt ggtttttgat attctcccaa caactctcat atgatttttg
    18721 tcttctccct tatattcaac aatcggaatc gaatctactt catgttctat tatttttctt
    18781 gaagctaata aaacacttgc tcctttagtt aaagtgacta catttggagt tcttgtcatt
    18841 atcataccta ttggcatttt atttatatca gaacctccta tagttgcttt tagcaagtct
    18901 tttctggaaa caactccaca taactcttca ttctcatcta taataactat actccctaca
    18961 tcagataaaa acatagtgac tattacatca tatatacttt catccttctt agctagtaca
    19021 ggcatgctca ttatatcctc tactgttttt tcttttacac ttttaccaat taaatttatt
    19081 tcactaactc ctgaataaaa atatccaact tttggtcttg cgtctaatat tcctgtcatt
    19141 gttaatatag ctaaatcaga tctaagtgta gcacgagtca cattcaagct ggaggcaata
    19201 ctttcactcg ttattggttc attttcctta actatatcta taatttttag ttgtctttca
    19261 ttaagctgaa taataatcac cttctttcat tgtgctatac tttttatctt ttcgcatctt
    19321 atatagtata ttatataact atatatacca ttctgtaaac agatttttta ttgaatacga
    19381 tatatttttt actaagttct ctcgcttaaa gatatttatt atatattaat gggggatatt
    19441 tctttaatta atagaactat attagtatta cagttaatat tataatacat aattggtcat
    19501 tttaattcat tttatattaa aatttttaat aatattattt caatgtgaat ataaaattgc
    19561 agaactaatt caaaataatt tttacgacta caaataacct ataatatact tttaaagaaa
    19621 gtatcctaac aagaatatat aaaaatttaa aagggttgat ttaaaaataa ccatcaaccc
    19681 tttttactaa tatctattta tattaccatc aaatcttacc caaatatttt ttcttgcaat
    19741 tgtcttaaat gatataaagt agtatctttt tctatctcta ccatatcgta agttataact
    19801 tcaccttttt taatatcttt tacaacttta gtctttttac ttatcaaacc aataggtaca
    19861 gcattcatag cctttgctac atcgtatttt tctatagtac catagcatgt atatgctcca
    19921 tagccatcca taaactcacc ttttttcaaa tctttcttag ctatagtcat aacttctgct
    19981 actagtccag ctttaggtac tattgtagcc ttatggtcta aaactgccat agctgctgat
    20041 aaaggagtct ctaaactaca taaatgatat ggtctatata atatgtaatt aggtccatca
    20101 cccatactta aatattttag ttcatcatta actgctttta atttatgggc aactactacg
    20161 aaaactccag gtgctatacc atttacaaaa tcaactacac cataattatc taatactcca
    20221 ccttcgcttt ttaatgcata tttcttaggt acttcattaa ctgtagcttc aataccatga
    20281 ccacctctta catcaggcac aaatccagtt gcattacaca ttaaagccat ttctaccatt
    20341 gttttagttc cttctttaaa agaagctatc atatgaggtg aagctccttt tctttctgct
    20401 tcttctctaa ctgtatcagg attacaatct aaatctaatt tattattttt acctttacct
    20461 atcactctaa cttcaaaccc cattgcatct gcaaaatcaa ataattccat tactgcacct
    20521 ggctcatctc ctgcagaacc tgtaaatatt actccagcat catctgctaa ttttttaagt
    20581 attggtccaa caacacaatc agtttcagca tttaacataa ctatatgttt tttatttaaa
    20641 atagagttta atgctatctc tgcaccaatt gcaatacccc cagttgcatc tataactaca
    20701 tctattgact tagttttaca agccacaaga aagtcattac atgtcaatac ttttccttct
    20761 tgtaatttta tttctgcatc cttttcattt gttacattat ctataatttc ttcatctatt
    20821 cctgcatcag taaaagcttt atgagccaac tccaaatcta tatctacaac aatagaagct
    20881 tcaatacctt tcatatttgc catttggctt accattccat ttcccatatg cccagctcct
    20941 ataagagcta cttttatttt tttaccttcc tcttccaatt ttgcaagttt tctgtttaaa
    21001 tctaacatac caattcctcc tgttataata attttatttt caaattaaga aatagttatt
    21061 aaatctccaa tagttatatc tggatttcct atttccacat gtatttctcc tggtaaattt
    21121 acttcacatt ttccatcaaa tttgattgta caatgcccaa tttctctaag agtcttctga
    21181 gcaatatcac caactgaaac tatacaataa tctctattcc ctatagtaag tgtatctcct
    21241 atttcaacat cactttttaa tgttgctatt gaatgaatta cagatatatc ctttaagtcg
    21301 tcatcattaa tggtttcatc atatataata agacaattgc tttcatccat taactcttta
    21361 actaaactgc ctatcccact tatcttaact tcatatttca tgacattcct cctgataatt
    21421 tatatttata ttgagttaat taaaagaaac atttattttt tcttttataa attttatagc
    21481 ttgtacaata ctctcttcat ctttaaattt ttgctctgca ctatatatat ctaatccttc
    21541 tatttcttca atctctttaa atttagccat tactgtacgc ccttttaaaa tttctccaaa
    21601 ctttataaac ccatctgaat ctgaagatat aacggctata cttcctttag aaaaatagct
    21661 tttctttttg cctgtagaca ctatatcacc ctttttttta gctctattta aagttttaaa
    21721 atacaattta ttctgcttca ttataaatat agtatttaaa atataagcaa caaataaaat
    21781 tactaataat ttcatattta tacaccttcc aaaaatcaca ttatttttaa atctgtataa
    21841 caactataaa tgctgtacaa tagttatata aggtttttaa gtaacacctt tttaaattct
    21901 aaaaaagttc tacatttact tatcttattc gttaatttta catcttggcc tatctttaaa
    21961 acttcttcat aaatttttac taataagtct gagtctatct tattctcaca tggaaacatt
    22021 gtcataagaa ttatttttat acttctattt gcatattcta ttggttcttc taaaattcca
    22081 actgccatta aaaacttatc tgatttttca tttatagaat gaggaaataa taaaccttta
    22141 tcaaatactg tgggagattt ttcttctcta ttgactatat tttttctaaa cttctcatca
    22201 atacatccca aatccataag atggtccatc attttttcta atgaggcaag tatagtcttt
    22261 tcatttaata tcataaattt atcttcatct aacaaattat ttattagtaa atttgtagaa
    22321 ttagtagtgt caatattccc ttctcttagg cacaatactg tttttaattg ttctcttagt
    22381 ttgttttcat caaatattgt atttattttt aatactattg tatttatatt tgatgtgtct
    22441 aaatcaatag ttgtaaaaac tatatcgtat tcatctaagt taatatttct caaattaaaa
    22501 cttgaaagag tatcaatttt aggattattt cctatcagtt tttctactct tattttcaat
    22561 agttttgctg ttcctagacc tgtactacat ataattgcta ttttttttat tgaatagaat
    22621 ctactgctat ttctttctaa atatccactg aaatggattg ctatatatcc aatctcatct
    22681 tctgaaactt ctaagttata ctttttctct attacttttc ctgctatttg tgctaattta
    22741 aatggaagta tataattttg cttaatctct tctaacaaaa cattttttaa ctttatatta
    22801 aataatagcc tgtttaaagt aaaactaaga tgatatccta gacctactct taattcatcc
    22861 tcatttataa aaatacccat atcgacatat atttgattaa atatattttc catcaactca
    22921 tcaatgtttt tactaattct actactattt aaagcacatt ctgatgctgg tgcatttcca
    22981 ctaactaacg gtatagttaa ataaataatt tcttcatcat ttaaagtaca ttcaaacatt
    23041 cctgatatta tatgttttat ttccctagca ataaagtatt catcatatga tttaagtaaa
    23101 tcaaacttta catcataatc ttttactttc ttttcttctt ttactctata gactaaaact
    23161 actatgtagt taataacttc tcttaacatt tcatctgtaa cataaaaatt atttttttta
    23221 aataaagtca atagtttttc ttctaaattt atgatttctt cttttttgat tcctttaaaa
    23281 tactttgaat tactgaaatc tttccttgag tttttataca actgatttaa tataaacagt
    23341 ctaatatcaa gttcatttcc atttaatttc atacctgtat tctgtttttt aatcaagttt
    23401 aaattatatg aagccaaaac tttttctaca tactggaaat catttactaa agtagttctt
    23461 cctacacaca tctcatcagc taaactatca agtgtaataa atccatctag ttctatcaag
    23521 taatttagta taaactctac tctatcttct tttgaattta atgaaaatac attttttcta
    23581 ttcatatcaa taatcttatt gagtatctgc tcatctttta tttctagttt atagccttga
    23641 ccctttatat atttgattac tgctatatca ttacctaaat ctttattcaa ttgttttata
    23701 tacgtcctta cacttctagt tgtgacattc aattcatttg ctattgagtt aatactcaca
    23761 aactcttttt tactacacat aatcaatatc ttaaatatct tgcggtcaat agaaggaatt
    23821 ttctcagtta cactcatttt gtatctcctc cttgatttca ttctagtaca aatttgaaac
    23881 caaattaata cataaaattt cactttaata aaggaaaatt tagtattaat ctaactcgat
    23941 aattacagct aattaatagt ataaaagcta gtctttcatt aacaaaaaat cttgactagc
    24001 ttaaatttat atttacaatt ttattaatta attccaagcc ttatattgac attaaatatt
    24061 atctcaatgc aaatactgca actccatatg caataataac agctattgga ccagttatta
    24121 aacgagagta aaataaagct ggaacaccat actctacagt ttctggttct gcttctccca
    24181 aacttaatcc tactggtaca aaatcacatc cagcttgccc atttattgca aataaagctg
    24241 gaagtgctaa atatgctggt attgcaccaa gaccaatttg tgtacctaca agagtcccta
    24301 ctacttgagc tataactgca ccaggtccta gtattggtga taagaatgga agtgtgcaaa
    24361 ttactgatat aatcaataat ccaccaatat tacctgcaag tggagatata actcttgcaa
    24421 tccagtctcc cagtccagat gctaaaataa ttcccataag catacttaca aatgccataa
    24481 atggtattac gttattcatt accatttgga tagtatctcg acctgcatca taaaattttg
    24541 atactacttg ccctgcccct tgaccaatag aaagtattat gttcttttta gcatattcac
    24601 cttgtgcttt tgacttaacc tcatcataat tatcaggctt tctaatagaa ctcttatttt
    24661 cgcttttatt ttcttgagat ttttgtggca tatcttcccc atctacaaca cttatacagt
    24721 taggattaac atctgataca taatattctt ctgttataaa ttttgctaaa ggacctgttt
    24781 ttccaactgg atttacattt attgtaggta tttttttctt tggataaact ccacatctag
    24841 cagttccacc acaatcaata ataactactg ctacttcttc atcagaaact ccagttttaa
    24901 atccatctac aatttcacaa cccagtagtt cttttatttt taatgttact tcatggatac
    24961 cgccagcagt cattgatagt atcttatttc tattcccttc tttttttata tacaaaggac
    25021 ctccccagcc tgaagttccc ttttctattt ttaatatttt attctcctcc attttatcta
    25081 cctcctaagc cttatttgtt gctctatttt ttcttgttag aaaagcatac attttttctg
    25141 ttactatacc tcttataaaa attacaatta gaccaactat aaaataccac aatgccaatg
    25201 tagtagtttc tttacctaaa gtagtcaaac ctgcagatat tcccaaccat acaaaaagtt
    25261 ctcctgcatt tgcatgtgga aaaagacctg taattggatg tacaaatgaa actgctgcat
    25321 cataaaatcc tgctttgtgc tcttctttta aaaatctacc aaatgtatag cacataggat
    25381 ttcccaagaa aaatactgat actaatggaa gtagaatata tcttgtaaaa gagttctttc
    25441 ctagcttaga agcccaatta ttaactcttt cctcaccaat tatcttaatc aaagagttaa
    25501 tagctaccat taatacaatt agcgttggaa gagtacctga aacaagacct ataaattgtt
    25561 ctcccccttt ctgaaacaaa ccgataaacc actctgcacc tttacttaga cctgtaataa
    25621 cgttttccat aaaattataa cctccctata atatctttaa atttttaatt ttactgctta
    25681 ccataaattt tacaaattac atcttttttc tgtactatat gctaatattg taaatgtttt
    25741 tttattaata tcattttaat ataatatttt tga
//
LOCUS       DAMJWC010000053        24768 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMJWC010000053 DAMJWC010000000
VERSION     DAMJWC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.053"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            160..528
                     /locus_tag="PC503_002612"
     CDS             160..528
                     /locus_tag="PC503_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2528578.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            531..902
                     /locus_tag="PC503_002613"
     CDS             531..902
                     /locus_tag="PC503_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF2528579.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(1047..1502)
                     /locus_tag="PC503_002614"
     CDS             complement(1047..1502)
                     /locus_tag="PC503_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528580.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(1541..2806)
                     /locus_tag="PC503_002615"
     CDS             complement(1541..2806)
                     /locus_tag="PC503_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF2528581.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            3276..4727
                     /locus_tag="PC503_002616"
     CDS             3276..4727
                     /locus_tag="PC503_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2528582.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(4946..5407)
                     /locus_tag="PC503_002617"
     CDS             complement(4946..5407)
                     /locus_tag="PC503_002617"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF2528583.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(5512..6705)
                     /locus_tag="PC503_002618"
     CDS             complement(5512..6705)
                     /locus_tag="PC503_002618"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF2528584.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(6728..7393)
                     /locus_tag="PC503_002619"
     CDS             complement(6728..7393)
                     /locus_tag="PC503_002619"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF2528585.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(7427..8539)
                     /gene="ribD"
                     /locus_tag="PC503_002620"
     CDS             complement(7427..8539)
                     /gene="ribD"
                     /locus_tag="PC503_002620"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF2528586.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(8671..8792)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            8981..11464
                     /gene="recQ"
                     /locus_tag="PC503_002621"
     CDS             8981..11464
                     /gene="recQ"
                     /locus_tag="PC503_002621"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF2528587.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      11553..11664
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11806..13107
                     /gene="thiC"
                     /locus_tag="PC503_002622"
     CDS             11806..13107
                     /gene="thiC"
                     /locus_tag="PC503_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2528588.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            13161..13355
                     /gene="thiS"
                     /locus_tag="PC503_002623"
     CDS             13161..13355
                     /gene="thiS"
                     /locus_tag="PC503_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF2528589.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            13348..14151
                     /gene="thiF"
                     /locus_tag="PC503_002624"
     CDS             13348..14151
                     /gene="thiF"
                     /locus_tag="PC503_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF2528590.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            14214..14984
                     /locus_tag="PC503_002625"
     CDS             14214..14984
                     /locus_tag="PC503_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF2528591.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            15001..16104
                     /gene="thiH"
                     /locus_tag="PC503_002626"
     CDS             15001..16104
                     /gene="thiH"
                     /locus_tag="PC503_002626"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF2528592.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEVISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            16105..16794
                     /locus_tag="PC503_002627"
     CDS             16105..16794
                     /locus_tag="PC503_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2528593.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            16982..18376
                     /gene="yfcC"
                     /locus_tag="PC503_002628"
     CDS             16982..18376
                     /gene="yfcC"
                     /locus_tag="PC503_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF2528594.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            18893..20260
                     /locus_tag="PC503_002629"
     CDS             18893..20260
                     /locus_tag="PC503_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF2528595.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            20285..20893
                     /locus_tag="PC503_002630"
     CDS             20285..20893
                     /locus_tag="PC503_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF2528596.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            20941..21312
                     /locus_tag="PC503_002631"
     CDS             20941..21312
                     /locus_tag="PC503_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF2528597.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            21491..21829
                     /locus_tag="PC503_002632"
     CDS             21491..21829
                     /locus_tag="PC503_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF2528598.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            22295..22798
                     /locus_tag="PC503_002633"
     CDS             22295..22798
                     /locus_tag="PC503_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF2528599.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGVYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            22845..23804
                     /gene="moaA"
                     /locus_tag="PC503_002634"
     CDS             22845..23804
                     /gene="moaA"
                     /locus_tag="PC503_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF2528600.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            23808..24278
                     /gene="moaC"
                     /locus_tag="PC503_002635"
     CDS             23808..24278
                     /gene="moaC"
                     /locus_tag="PC503_002635"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF2528601.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            24314..24745
                     /locus_tag="PC503_002636"
     CDS             24314..24745
                     /locus_tag="PC503_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF2528602.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         9518 a         2765 c         4161 g         8324 t
ORIGIN      
        1 atctatatgt aattactttt attaataaaa ctcaaagtta tattagtaaa aattggaatt
       61 atttataata tactccaaaa tttaaaaata atggttgaaa aatctaatta agagtactat
      121 aatttaatta agtaattact taatcaaaat gaggtactta tggaaaactt ggttaaaata
      181 tttaaagcat tgagtgatga aactagactt aacatactta tattagtatc caagagaaat
      241 atatgtcaaa aggggatttc taaatatcta gggatttcag attctgctgt ttcacaacat
      301 ataaaaatat taaaagatgt tgggataata acaggatata aagaaggata ctatgtttta
      361 tatcatatta ataaagaatc atttaatata tgtgtagatt ttataaattc tatgttaagt
      421 aattctagtg aaagctttat agatgtattt gatgtaaata caatacatct aggatgcagt
      481 aaagaatgta aatctataaa aaaatgttgt aagagaaggg agaaataata atgaaagtat
      541 gtataccagt agaggagaat aaaggattgg atagtaaacc atatggacat tttggttctg
      601 ctccaatttt tgttgtgtgt gatttagaaa gtggagaagt taaatcttta gataatggag
      661 atttagatca tgaacatgga aaatgtcaac cattaaaagc attgtcaggg acagctgtag
      721 atgcagtagt tgttggagga ataggacaag gagctataat taaattaaat ggaatgggaa
      781 taaaagttta cagagcagaa ggtgatacta taagtgctaa tttagactta cttaaaaatg
      841 gaaaattagt agaatttcca tcagaccata cttgctcaca tgacggatgt ggacatcatt
      901 aaaaaaaaac agctgatgaa atatatactt catcagctat tttttctttt aataaatacg
      961 attttattct tttaaaacca aaatttagat ttttatgttt tttgtagtat ccttaataat
     1021 atttcaagtt tacaagttta ctacttttag attttttttg tatgtttttc tatatagtca
     1081 atatcattta atatgtcatt gagttcttta ttaagtgttt ttaaatcatc accatctaca
     1141 ttgtagttta aaaatagttc ctctacatta tcaatgatag aattgacttt tctagtaact
     1201 tcaacaaatg tcttaaagtt actactattt ttagcattta gaaatttttt taaatccttt
     1261 gatataaatg atactatttc atattcatca ttaaatagac ctctaccaat aggatatggt
     1321 tcaattctct gtaaaaaata ttggtcttta gcattaatat tataagtata agatatttcc
     1381 caaccgtctc ctaaatcaaa cttgataaaa tataatgtac tacttacttt tgatattctt
     1441 gtggcaccaa gctgtcttaa aagaacttca atcgaatcac cttgaacagt attaatattc
     1501 atatatacac atccccttta gtattattat actatatttt ttaaaatttt ataattaaat
     1561 aaacagtaga tataataata gatataatca taagtggaaa acctattttg aaatactcct
     1621 taaaagagat aggatgaccg tgtttattac ctatacctgc tagtacaaca ttagcagatg
     1681 ctcctattag tgttccattt cctccaagac aagctccaag agatgttgcc caccatagtg
     1741 gcattacatc aataccttca gcttgcatag tcaaaataag aggaattagt gttgcaacaa
     1801 atggaatatt atctaagaaa gaagagacta tagctgacaa ccataatatc aacaacattg
     1861 taaatacaag atgtccttct gtaagtccaa tcaatgcttg agccaatttg tttattatcc
     1921 caacttctac taatccacca actactacaa ataatcccat aaagaataaa attgtagacc
     1981 attcaatacc tgccataatt tcatctacat cttgttttcc tattaaaagc attatagatg
     2041 ctcctgtcag tgctacaaca gaagaatcta tgtggattgt actgtgaaac ataaaaccaa
     2101 aaagtatgaa tgctattaat ataaggcttt ttataagtag aggtttatct ttaacagatt
     2161 ttttttcatc tagttttaat attgcatttt tagctctttc attcacaaca agttcttttc
     2221 cataaataaa tctaaagcat attatagtta tagcaagtat tactataaca gcaggaccta
     2281 aatttattac aaaatccata aaactaagat tggcagcact accaatcata atatttggag
     2341 ggtctcctat aagagtagct gttcctccta tatttgaagc taaaatctgt gttattaaaa
     2401 atggaactgg attaagtcct aatatttgtg taataactat agtcattggt ccaataagta
     2461 agacggttgt aacattatct aatacagctg ataaaatagc tgttataata gcaaaacaaa
     2521 tcattatctt ccatgggtca cctttggctt tctttgcagt ccagatagct atatattcaa
     2581 ataaccccga gtttttgaca acagctacaa atagcatcat accaactaat acaccaatag
     2641 tattgaaatc tatatggctt aatccttcat caagtgtaag tatattgaat attatcatta
     2701 atagtgcacc accaacagct gctacggatc tgtttacctt ttctgtaata atagctgcca
     2761 taactattaa aaatatacat atagctatta tttgttgaaa ttccataata taagtacctc
     2821 catttgtatt attttgtgcc taatgctagt actatatata gtattacttt tttattgttt
     2881 tttcaatgga tgtatgaaag tatattattt aacaaagttt ttggaaaatt gacagaattt
     2941 aaagaaaatt tttgttattt aaataaattt taaaattatt ccattgataa taatattaaa
     3001 cgacaaacga aaaaatatac cctttaaact agaatttatt gtatctaata acaattataa
     3061 aatattaaat atatctatat tataaaaaca ataaaaaaag gtttgatttg aatataaaac
     3121 tgcaatatat taaaaaaatt attcatttta aaccttgtaa tttgatttta taaatattat
     3181 aattaaatta atgaattttt aacaaggaat tattcatttt tttgatttta agatttattg
     3241 agaaaacaaa actaaatagg ggggtaatta atataatgga ttttttcaat ggtattttaa
     3301 cgagtattaa caatgcagta gtatatgtaa acaattactt atggtcgtat atcttaatta
     3361 taatgttagt tgtaattggt atttacttta ctattaaaac aaattttgta caattcagat
     3421 attttataga aatgtttaga cttctgggtg atggtacagc gaataaaaat gcaaaaaagg
     3481 aaggaaaaat ctcttcattt caagcatttt gtataagtac atcttcaaga gttggaactg
     3541 gaaatatagc tggaatagca attgcagtgg tagcaggagg acctggtgct gtattttgga
     3601 tgtggcttat agcattaatt ggttctgcat caagctttgt tgagagtaca ttagctcaga
     3661 tttacaaagt gaaagatggt caagctttta gaggtggacc agcgtattat atggaacaag
     3721 gtctaaataa aaaatggatg ggtattttat tctcaatact tataactata tgttatggtt
     3781 ttgtatttaa tgcagttcaa gcaaatactg tttcacttgc atttaataat gcatttggaa
     3841 taagtaaaat ggctatggga ataggtcttg gaattttaac tgcaatagtt atttttggtg
     3901 gagtgcatag agttgcaaaa gtttctgaaa taatagttcc tgtatttgca ggattatata
     3961 tattagttgc tttggctata gttgtaatga atataacaga gataccaagt gttatagcat
     4021 tgatagttga aagtgcattt gattttaaag gaatggcgat tggtacattt atgggagttg
     4081 taatgactgg agtgaagaga ggtctatttt ctaatgaagc aggtatgggt agtgctccta
     4141 atgctgctgc aacagcacat gtaactcatc ctgtaaaaca aggtttaatt caatctttag
     4201 gtgtttttac agatactata ataatatgta gttgtacagc attcatggta ttattatatt
     4261 caggttatag tagtagtgga gcaactggaa ttgaattagc tcaagaagct ttaactcatc
     4321 atataggacc agttggaaat atatttatag cagtttgtat attcttgttt gcatttagtt
     4381 ctatagttgg taattactat tatggtgaat caaatatgga gtttatgagt ggaagtaaga
     4441 ctaaacttaa tgtatttaga gtttttgttg taggtatggt tttatttggt tcacttactc
     4501 aagtggatgt agtttggaat cttgcagact tatttatggc attgatggcg ataataaact
     4561 taatagcaat agcactttta ggaaaatatg catttattgc tttaaaagat tatacaagtc
     4621 aaaaaaaatc aggaataaaa gaccctgtgt ttattgcaga tgaaatagaa ggcctagaaa
     4681 aggtatcaga gtggcatagg gaattatctg aggaacattt aggataaaaa atagtataaa
     4741 attataaaac cattttgaaa gactagagta tgtatatact ttatatgaat ataatattga
     4801 attaatttat attactggaa tttttaattc cagtaatatt tttttattat ataatttagc
     4861 tttattaaaa gtttttatta ttaaaaatag cttatttatc gtaaagtgaa tgatattggg
     4921 ttttaattat tatgaatgtt agtatttaat ttaaagactt aaataaattt gccatttcta
     4981 gcgcattcat agcacaatca taacctttat ttccagcttt tgtacctgct ctttcaatag
     5041 cttgttcaat attttctgta gttacgattc caaatataac aggtaattca ctgtctaaag
     5101 atactttggc tatcccttta gagacttcac tacatacata atcataatga gaagtagccc
     5161 ctcttataac acagcctaaa cagattatag catcatactt accactttta gccatttttt
     5221 gagcaacaag aggaatctca aaagctccag gtacccaaac tatttctata ttttctggag
     5281 aaacgtcatg tcttaaaaga cagtcttcag ctcctgataa aagttttgat gttataaatt
     5341 cattaaaacg agaatttatt atacctattt ttaaatcttt tccaataagt tttccttcat
     5401 atatcatttt tacttcctcc aattttattt atgttataga tttatattta taaatatctt
     5461 taatttaatt ataaaaaact acttagtaga aaaatatcat catataatca tttatataat
     5521 atctaaaaga tgtcccattt tatctttttt agtttttaaa tatagcttat taaagtcatt
     5581 aatttcttca ttaataggga ttctattttc gatttttatt ccatatttct ctaattgatt
     5641 tattttatct gggttattac ttaaaagatt tatacttttt atgtttaaat tttttaatat
     5701 ttgagcagcc atatagaaat ctctcatatc ttcttcaaat ccaagcatta aatttgcttc
     5761 aacagtatcg taaccttctt cttgaagttt ataagcctta attttattta aaagaccaat
     5821 acctctacct tcttgcttca tataaattaa aactccactt ccattttcca caattttctt
     5881 catagaagat tctagctgta atccacaatc acattttaga gagtggaaca catctcctgt
     5941 taaacattca gaatgaagtc taactagagt attttctata tttatatttc cataagtaag
     6001 ggcaatgtgt tcttcatttg aataagtatc tctatatcct atgatttcaa aatttccata
     6061 ttttgtcgga aggaaagcac tagatacttt ttctatagta gtttcattta ttttgcggta
     6121 ttctataagg tcttttatag tgatgatttt taaattatgc ttttctttga aaatcattaa
     6181 atcatcaact cttgccattg taccatcatc tttcattatt tcacagataa gaccaatctc
     6241 tttaaaacct gcaagtctag caaggtctac tgaggcttct gtatgtccat ccctgacaag
     6301 aaccccacca gtttttgcta ttaaaggaaa gatgtgacca ggcgttttga aatctttact
     6361 tgtagaattt tcatcacaga ataattttac agtttcagct ctttcatatg cagatatacc
     6421 agttagagta tctgctccat ctatagtaac agtaaaggct gtttgaaatg tatctgtatt
     6481 ttctctaacc ataagaggta tattaagact tttaaatttt ttttcagtgg caggtagaca
     6541 aattagacct ctaccatatg tagccataaa atttattgat tcaggagtag ccatttcagc
     6601 tgccatcaat aaatctcctt cattctctct actttcatca tcaaccacga ttaccatttt
     6661 cccatttttt atatcttcaa tagcttcttc aatagtatta aacatgtaat tcactccttt
     6721 attattttta aaaaccattt ttaaataaaa aatctttatc tatatttgat ttatggttat
     6781 tactattaga atttaattcc ttgtagttat tagccataaa attattaaca tactttccaa
     6841 ttacatcgct ttctaaatta acgaaatctc caacattctt tgtcaagaga atagtgttaa
     6901 ttttagtatg aggtataata gaaaccttaa atatttcatc atctaaatat gatatagtta
     6961 aacttacacc atcaatagca acagaacctt tgagtatcat tgaggataaa agttttttat
     7021 caggtcgtat acttactaaa actgcatttt catctttttc aaatttgcag atagttcctt
     7081 taccatcaac atgacctgtt actatatgac caccaaatct tgaagaaaga ctcatagctc
     7141 tttcaagatt taccttgtca tttgcattta ataaacctaa atttgtggaa cgaattgtct
     7201 ccatcataac atcggctgta aattcatttt ttccgaggtt tgaaacagtt agacaaactc
     7261 catttacggc tatactatct ccaagatttg tgccatctaa tattttattt gatagtatgg
     7321 ttacttttcc actcttacca ttagcagtaa tttttctaag tattccaact tcttctacta
     7381 tgccagtaaa catcctaacc tcctatatga atgtattaac aaaaatttaa tttaaaacat
     7441 ctgattctat aagaatatcg ccatctatca aagttacatt attgattgtt aactgtgttg
     7501 aatctgacaa atgatttatt ccttctccag aaacgaatgt aggtgcatct ttaccaccta
     7561 taatcttggg tgatagaaat aatttgacct tatcaactaa cttatttcta aagagactgt
     7621 cattgagagt agcaccacct tcaactagaa cagaatcaat gtttaactct cctaatttat
     7681 acattacaaa ctccaaatct actaagttgt tttttgaagg agaaattatt gtttcaacat
     7741 tattttcttt taacatagat aattttatac tttctttgca acatgtgaaa actatagttt
     7801 tactggtttt atctttaacc aaattactat taagtggcaa ctttaggtgt gtatctatta
     7861 ctattcttgt aggatgagac actttttctt gattgagcct acaagttagt aaaggattat
     7921 cgttcaaaac tgtatttatg ccaaccatta tactttggta tttatttctg tatttatgag
     7981 ttagatacct tgatgattca ttagatatcc attttgattc tagtgatttt gtagcaattt
     8041 taccatctag acttactgct gattttacaa tacaaagagg tcttttgttt tttatatgat
     8101 aaaaaaatgc ctcatttaaa tctcttgctt catcttctaa tattcccaca gtaacatcaa
     8161 tattgttatc ttttaatttt tttactccat taccacaaac aagtggattt gggtctaatg
     8221 tagatattac aactctctta atcttatttt gtataatttt atctacacaa ggaggcgttt
     8281 tcccataatg agaacatggt tctaagttta cataaagagt agagtctttt agactttgtt
     8341 tagcactgtt tatagcattt acttcagcat gattagagcc aaatttctca tgatatcctt
     8401 tgcctattat attactagct ttaacaatta cacacccaac taatggattt ggatttacaa
     8461 agccttctcc atttttagcc aattcaatag cttttttcat ataataaata tctttttctt
     8521 tttgattcac aaaattcaca atatgtacac ctcctgttta attggataat ttttaaacaa
     8581 aaaaccctga gaattaactc agggtttaga ataatctaca ataaatgttt aataaatgta
     8641 gaacaaaatt gctctacaaa aacactcatt aaatatcttc ttccatccag actttactgt
     8701 cggctttgga atttaaccaa atcaaccaag ttttaccttg gctcgcgggc tataccgccg
     8761 attgggaatt tcaccctacc ccgaagatta agtattaaat ttatatttag aatgtatcat
     8821 aaattatttt actttgcaaa ctattttttt aaaaaatata tgttaatata taatatagaa
     8881 tgtctataaa ctttgaaata ccacgattgt gaatataaaa ataaaaattt gaacataatc
     8941 aggaaagaag tctaattaat ttaaattagg agagtaatat atgaataaaa aacttttaga
     9001 aatactatca aaatactatg gatatacaag ttttagaaaa ggtcaagaat ctataataaa
     9061 ctctatctta agcgaaaaag atgtgttagc tattatgcca acaggagggg gaaaatcaat
     9121 atgttatcaa attccagctt tgattttaga tggaatgaca atagtaattt ctccacttat
     9181 atcacttatg aaagaccaag tagatgcctt aaagactatg ggaattagtg ctgcttttat
     9241 aaatagttca ttaagtagca aagaatttaa tgaaatatta aataatatta gaaaaaataa
     9301 ttataaaata ctctatattg ctccagagag attagatgca caagagttta ttgagctaat
     9361 aaataataac aatgtaagtc aagttgcgat agatgaagca cattgtgtat ctcaatgggg
     9421 gcatgatttt aggttgagtt atagaaggat ttctgatttt ataaaaaatt tgcctaaaag
     9481 acctatagtt acagcattta ctgcaacagc ttcagaagag gtaagaactg atataataaa
     9541 tttactgtgt ttagaaaatc cagattatta tataactgga tttgatagag agaatttatc
     9601 aataaatata gtaaaatcat ctagtaaaaa taagtatatt ttagattata ttcaaaatca
     9661 taaaaatgag tctggaatta tatatgttgc aactagaaag gaagttgaaa atatatataa
     9721 tggtttatct aagagaaata tatctgtgtc aaaatatcat gcaggtttat ctaaaaatga
     9781 aagaagtaaa aatcaagaag attttataaa tgataatgtg gatataatgg tagcaacaaa
     9841 tgcatttgga atgggtattg ataaacctaa tataagatgg gttatacatt acaatatgcc
     9901 tcaaagtata gaaaactact atcaagaaat aggtagagct ggtagggatg gagaaaaaag
     9961 tgagtgtgta cttttatttt ctccaggaga tgtacatata caaaaatatt taattgatat
    10021 tggagttgaa aatcctgaaa gaaaattatt tcagcataag aagcttcaat acatgattga
    10081 cttagtttac agtaattcat gctatagaaa gacaatattg agttattttg gagaaaatta
    10141 tatagacaat tgcaataatt gtagcaattg tttagtagag ggtgaaatag tagataaaac
    10201 tatagatgca caaaaagtca tttcatgtgt agctagaatg aaaagaagtt atggtgttac
    10261 tactattgta gatgtgctta gaggttctaa gaataaaaag attttacagc ttggattaaa
    10321 tactttgtct acatataaca ttatgagaga ttattctagt gaagacttaa agaattttgt
    10381 aaatacattg gtttctcatg gttttttaga tttagttgag actctaggca atggaaatag
    10441 aggtagtttt cctactataa gattaaatga gatgtctatg aaagttttaa aaggtgaagt
    10501 gaaagtagag tttaaagaaa ttgttatgac aaaatcattg gaagtagagg atgagttata
    10561 taatgcttta agagaactta gacattcaat tgcaagtgaa gaaaggatag ctccatatat
    10621 ggtatttgga gatggtacac ttagagccat gtctagtagt tatccaatta ataaagaaga
    10681 aatgctagat atctctggag taggagaaat taaatatcaa aaatatggta gagattttga
    10741 agcagtaatt aaagaatatg tcgaaaaaaa taatataaat aaaaaaatag atgaaaaaaa
    10801 tgtcgattca aagaacgtta atagtgattt cttagaggtt aatacagata aagttttata
    10861 tgaaaaactg ttagtcatta gagaagaata tgcaacaaag gaaaaattac ctgcatatat
    10921 gattttagcc aataaggctt tgaaagaaat aagtggaaga tatccacttg atgaagaaca
    10981 attaaaagat atttctggca taggtggagt aaaatttgaa aaatatggag ctagtatttt
    11041 ggcagaggtt aataaatatg taaaagaaaa taatattaat gttatttggg agaaaaaggg
    11101 caaaaggaag ttaatattag atggagaaag tagaaaaaat aatgaaatag cattagattt
    11161 gctaaatcaa ggaaaagata tacaaagtat cagtcaagaa atagaagttt cactgtcaac
    11221 cattattgga tatgtgcatg actatgtaaa ggatggacat agtatatcat ttgaattagg
    11281 actagaaaat ttttataatg aagataaaaa gaagatgatt ttagaagttt gcgaaaaagt
    11341 tggctatgat aatttaaata acataaaaag aaaacttcca gattcaataa agtatgaaaa
    11401 tataagagct gtgatacttg actcttatct tgaaaactta aaaaataata ttatagcaga
    11461 gtaattttta acttaataaa aaataaaatt tgtattattg tgttgaacta ataattttgc
    11521 tgtgttatac tgaatttgta aaaataatga aaaattagag ctaggggcgc tagaattggc
    11581 tagctgagag ataaagccgt aacttacaaa ccctaataac ctgatcaaga taatgcttgc
    11641 gaagggaagc tttttaatat aattttatta tataaatagg caaattattc aatgttagga
    11701 gaaatttgtc taagtgtata tacgattata agagtgcttt ccaaacgagg aaaagcactt
    11761 tttttatttt caaaaactat aactttaatc ttggaggatt gtaatatgaa ctatacaaca
    11821 caaatggatg ctgctagaaa aggcataata actaaagaaa tggaaatcgt ttctcaaaaa
    11881 gaacaggtag atgtaaatga attaagagaa ttaatagcaa atggacaagt tgttatacca
    11941 gctaataaaa atcataaatc tttaagtgca gaaggtgtag gtaaaaattt aagaacaaaa
    12001 ataaatgtaa atctaggaat ttcaagagat tgtaaggata tagaaaaaga acttgaaaaa
    12061 gttagagtag caatagacat gaaagctgaa gctataatgg atttaagtaa ttatggcaaa
    12121 actagagaat ttagagaaaa ggttgttgaa atgtcacctg caatgatagg ttcagtacct
    12181 atgtatgatg cagtaggata tttggaaaaa gaattaaaag atataacaga agaagagttt
    12241 ttaaatgtaa taagacaaca tgctattgat ggagtagact ttattactat acatgcaggt
    12301 cttacaagaa gtgtttgcca aaaaataaaa aatcatgaga gattgactca tatagtatct
    12361 cgtggaggtt ctttattgtt tgcatggatg gaattaaata ataaggaaaa tcctatttat
    12421 actaattttg ataaaatatt ggatatatgt gaagaatatg atgttacatt gagtttagga
    12481 gatgcttgta gaccaggttg tataaaagat tctactgatg gtgttcaaat tcaagaactt
    12541 gtagtattag gtgaacttac taaaagagca tgggaaagaa atgtacaagt aatgatagaa
    12601 ggtcctggac acatggctat tgatgaaata gaagcaaatg tagtattaga aaagagatta
    12661 tgccatggag caccttttta tgttcttgga ccattggtta cagatatagc accaggttat
    12721 gaccatataa caagtgcaat aggaggagct ttagcatgtg ccaaaggagt agatttttta
    12781 tgttatgtaa ctccagcaga acatttaaga ttgcctaatt tagatgatat gaaagagggt
    12841 ataatagctg caaagatagc tgctcatgca ggagatatag ctaaaaatgt taaaggtgct
    12901 cgtgaatggg ataataagat gagtaaagct agagctgatt tagactggtg tgagatgttt
    12961 agacttgcaa tagaccctga aaaagctaag agatacagag atgaatcaac tcctactcat
    13021 gaggatagtt gtactatgtg tggaaaaatg tgctcaatga gaacagttaa gaaaatatta
    13081 aacaatgagg aacttaatct aatataattt ttggctagta tgactggaat aaaaataagc
    13141 tgaaaagagg aggtgattta gtgaaggtta atgggaagga aattgaattt gaaaaagatt
    13201 tgactgttat agatttatta aataaatata atttaaaaag tgatagagtt gtagttgaag
    13261 tgaatttaga gataattgaa gaatctaact acaatacata tgtattaaaa gacgaggaca
    13321 ttgtagagct tattagcttt attggaggtg gttaaaataa aaatatttgt aaatgaatta
    13381 ttaacagatg ttgaggaaaa tacaactgct tataaagtta gagatagcta taacaataaa
    13441 tgtgatgtat tggtgttaaa tggatatcca attaaaacag atatgaccct ttgtgaaaat
    13501 gataaattaa cacttataca aaaaggagtt aagccatcac ttgatgaatt ggaaagcttg
    13561 ttgattgcta gacatactcc aaatatacat aataaattaa aaaaagggaa agttgctata
    13621 ttgggattgg ggggacttgg ttccaatata gctatctctt tagctagaat aggagtggga
    13681 gaacttttac ttatagatta tgatgttgta gaaccatcta atttaaatag acagcagtat
    13741 tttatagatg atataggaaa actaaaaact gatgccatga tagaaaatat aaaaaaaata
    13801 aatccattta taaaattaaa taaacgagat atttttttaa acaagaacaa tatggatact
    13861 attaaggatt cagatttaat aattgaggcc tttgatgatg cttcatgtaa agcacaggta
    13921 tgtaattatg tattaataaa tttaaaagat aaatatttaa tagcatcatc tggtatggca
    13981 ggttactatg attcaaatat aataactact aagaagataa aagacaggtt ttatatatgt
    14041 ggggattttg tgaatgaagc taaatttggt gaagggctta tggctccaag ggttgccatc
    14101 tgcgcaaatc atatggcaaa tttggcaacg caaatactta tagatatgta aatattaaaa
    14161 ttagatataa aaaagattga atattaaaaa aatttaacgt ggagggaaat aatatggata
    14221 aattggtact tggtggacat gaatttaata gcagattatt ggttggaaca ggtaaatatg
    14281 gttcaaataa tatattgcct gaggtaataa aagaaagtgg aagtgaaata ataacaatgg
    14341 cacttagaag agtggattta gacaataaac aagaaaacat attaacgtat attccaaaag
    14401 agatgacaat acttccaaat acatcaggag ctactaatgc agaagaagct gtaagaatag
    14461 ctagaatatc tagaaaaatg ggatgtggag attttataaa aatagaagta atatcagata
    14521 ctagatattt acttcctgat aatgaagaaa ctataaaagc tacaaagata cttgctgatg
    14581 aggggtttat agttcttcca tatatgacac cagaccttta tgctggaaga agacttatag
    14641 aagctaatgc agcggcagtt atgccacttg gagctccaat tggttcaaat agaggtcttc
    14701 aaatgaaaga aatgataaga ataatgatag atgagttgga tataccaata atagtagatg
    14761 caggtattgg aaaaccatct caagctatgg aggctatgga aatgggagct gatgcagtac
    14821 ttgtcaacac tgctatagct tcagcaggag accctgtaca aatggctaga gcatttaaat
    14881 tagctgtaga aggtggaaga gaagcatata ttgcaaaaac aggaaatgtg tcagaatttg
    14941 caaatgcatc ttctccttta acaggttttt taggcaattt atagaaagtg gtgattggtg
    15001 atgagttttt atgatgtaat agaaaaatat agggattttg attttgatgg atatttaaat
    15061 aatgttactg ataatgatgt tttaagaagt ttatcaaaag acaagcttga agattttgat
    15121 atattaaatt tgctttctaa aactgcagta aaacatttag aagatatggc acaaaaagca
    15181 cataaattaa gtgttcaata ctttggtaaa acagtatgtt tatatacacc aatgtatata
    15241 gcaaattatt gtgttaatca atgtgtttat tgtagctata atataaagag tggaataaaa
    15301 agaaaaaaat taactatgga tgaaattaga gaagagggag aagtaatttc aaaagaaggt
    15361 ttcaaacatc tacttgtttt gactggagaa agtagttttc actcaagtgt agaatatata
    15421 ggtgaggcta tagaaatatt aagagagaaa tttccctcta taggtataga agtttatcca
    15481 atggaagtag aagaatataa gtacattgta gataaaggtg ttgaaggatt aacagtatat
    15541 caagaaactt atgacgagga aatatataag agagtacata taaaaggccc aaaatcaaat
    15601 tataaattta gactagatgc tcctgaaaga ggggcaaaag caggtatgag gactttatca
    15661 ataggtgcac ttttagggct aaatgatttt agaaaagaaa ctttttttac aatattgcat
    15721 gggaaatact taaaaacgaa atatcctcat attgagcttt catattcaac accaagaatg
    15781 agacctttta aagggtgttt tgaggaattg gtagatataa gtgatactga tttagttcaa
    15841 gctatggtat gtatgagatt atttgaccct catgcagcta taaatatatc cactagagaa
    15901 aatttagaaa tgagaagtca tataatacct ttaggagtaa ctaaattgag tgcaggtgta
    15961 tctactgatg taggaggtca ttctcaagat gaacatgata ctgctcaatt taagataaat
    16021 gatgaaagta ctgttaaaga tgtggagaaa atgctaaact caattggtta tcagcatgtg
    16081 tttaaagatt gggaaagatt ttaaatgtat ctgataacaa acagaaaatt atgtagtgag
    16141 gaacgatatt tagaagttat taaagagtct atattgagtg gtgtagaaaa tataataata
    16201 agagaaaagg atttagaata tcaagagcta agaaaattat atatgaaaat aaaaactaaa
    16261 atcaattgta tagattttca agagcaaata tcagatgaaa gtttgaaaac taatataaat
    16321 caaaaagagt ttagaaataa attcaaggtt aattttataa taaatagtaa cattgaattt
    16381 tttgaaaaag tggattgtca aggtatccat cttcctttta aattattctt gaatttaatt
    16441 gaaaataagt ataattttaa tgaaaataaa atactaggat tatctttaca taaagtagag
    16501 gaagtagatt atttagaaaa attaataaga aatcaaaata taaaaataga ttacataaca
    16561 ttatcacata tatatgaaac taaatgtaaa gaaggattaa atccaaaagg aattgagctt
    16621 ttaaaagaag ctaaaaagat tactgatatt aaaataattg cacttggggg aattttacca
    16681 tctaatgtca aggaaacatt aaaatactgt gatgattttg ctataatgtc aactataatg
    16741 aggtctaaag atattaaaaa aaccatatca aattataatg aaaagttgaa ttagtaaata
    16801 tagtatattg aatttttaac ttaaataaaa ataaaaaagt tatcttttaa attttaaaag
    16861 gtagcttttt tattttatat ctttgctaat aaaaaattgt aaaaagggaa aactttagtc
    16921 agagagatta aacaatatcc tagaaagatt taaaatttag taaagtatgg aggacattat
    16981 aatgactgac agtaaaaaga aacgatttat tataccacac acttttacaa taatattttt
    17041 actaatagtc ttgatggcaa tattgacttg gatagtacca agtggtgaat ttagtagaga
    17101 agatgtagaa ggtagaatgg tagttgtacc agggacttat caaagtgtag aaagtaatcc
    17161 tcaaggattt gcagatgttt ttaaagcacc aatagaaggc tttatcgatt cagctgaagt
    17221 tgtaggtttt gttttaatag ttggaggtgc ttttggtatt gtaaatagga ctggagctat
    17281 agaagcagga atagcttcgg ttatctctaa gtttaaggga aaagaacttc ttataattcc
    17341 aatatcaatg attttatttg gacttggagg tacaacattt gggatggcag aagagacatt
    17401 accattttat atgatatttg ttccactcat gacatccttg ggatatgatt ctctaacagc
    17461 aatagcaatt gtatttatag gagcagcagc aggagcagcc gcttcaacaa taaatccatt
    17521 ttcagttggt attgcacagg cactagctca acttgctcct ggttcaggag taacttacag
    17581 agtagttatt tttatagcat atatactaat aagtatagca tttgttatgt actatgctaa
    17641 gaaggtaaag gaaaatcctg aaagttcaat agtatatgaa atagataaaa ataataaatc
    17701 aatacttaat caaacttcaa cagaaataaa agaatttact tttaaagaag tatctgttct
    17761 tgctatattt ggaataggga tggcaataat gatttggggt gttttaagtc aaggatggta
    17821 cattccagaa atatcaatgt gttttgctgc aataggtgtg ctttctggat tggttggtag
    17881 attatctcaa attgaaatct cagaaagttt tatagatgga gcaaaagatt tagcatctgc
    17941 agctcttgct atagctttgg ctcgtggaat cgtaataatt gctcaaaatg gatttataat
    18001 agatactata ttaaattccg cagcagcctt tctaggtggg cttccaaagg ttatatttgt
    18061 atatttatca tttttcttgg aagctgcatt ggcattttta attccatcat cttcaggtct
    18121 tgcttcactt acagtacctg tacttgctcc tcttggtgat ttggttaata tatcggctca
    18181 agtgatagta accgcttatc aatttggtgt gggtcttaca aactttataa ctccaacttc
    18241 aggagtactg atgggagcac ttgcagtagc ccatattcca ttttcaaaat gggtaagatt
    18301 tataatgcct atcttgttga ttttgacagc tgtatctcta gtctttttaa caataggtat
    18361 ttatataggg ttttaattaa gtgtagtttt atttaagata tttagtaatg gtataaaatg
    18421 ataatatgtt ttcaataaat tgccactaat ttaattagtg gtaatttgtt ttttgtattt
    18481 aaaaataaat gtatttactt gtattttgaa ttaatatcta cttagacatt gttttaattg
    18541 ttatattttt atttaattaa gcattgattt atcatttttt atatttcata taacaatgca
    18601 aaaaataatt tttatatagt aaatgacaaa agtttacaat aaatgtatat tttcttactc
    18661 attccttaaa attactcatt tagtttaata actctcattt catatgtaaa gttggtaaaa
    18721 aaattaaaat taaaagtaaa aaactaaata aattaatgtt aatttgaaat atatatgaag
    18781 gtttttggag aatacttact tatgatagga aaaaatgtta aaataatagt gtaatcaaat
    18841 ataaaggact gaaataatta acagttatta aatattagga gtgtaaaaat ttatgggatt
    18901 aaaagaattt gattttattg aagagtctat tgatatgttg aggacaatgt caccaacatt
    18961 agaaactata tcagatgaaa tagaagaata ttttgaaaat atcttggatg aaaagaatca
    19021 agaatatata aatgtaacct ctagaataaa atcagaatca agtttaagag aaaagataat
    19081 tagaaataga tatttaaaaa aatatggaga agcaagtaat cttattcata atgtttctga
    19141 cttaataggc ctaagaattg agtgtagatt tattgaggat gaaaacaaaa tatatagact
    19201 tttgagaaga tattttaata aaacagatga caaaataaac tattataata aagagaataa
    19261 gaatattaaa ttaaaactat ctgagaggca acccaataag caaaaaaatg gatttgaaat
    19321 atataaaata gatggagttt ttgcgtattt agatagagaa gtaaaatttg aacttcaaat
    19381 taaatctctt gtaaatgtgt tttggagtga aatagaacat aaaataattt ataaaaacaa
    19441 tacatattta cttgctgata aatttataaa ggatatgatg gactctataa agaataatct
    19501 tactatgata gataatcagc ttttaagtat ttataaaaac tttcattcag ggaagtcttt
    19561 taatatgaaa gtaagtaaaa aagaaattga aaaattattt gcgaaactag tctatgacgc
    19621 tttttctgaa aagatgaata aaagtatagg ttttgttgta gattttaaaa aaccatgtga
    19681 gactatattg aactattctt ttaataaaca agatataagt gatgaagttt taggtaattt
    19741 tatgcttgat gagtttgcaa gattaaatga aattgtaaac aaggatatag attttaatga
    19801 gcaaatagaa tttgaaagag aaccaacatt tgatgataag ttttgtaaag acctaggaaa
    19861 tcattttaga agtagattaa acacagaatt tccatggaac ctatttttta gaatattatt
    19921 tgaaatagag ccatataaca ataccaaaga ctttgaaaac tttgtagagt ttataaaaga
    19981 aaatgtgcta ctagaagaaa atagggagca attattatgc caatttgaag aggatagtaa
    20041 gcttataatt gaagatatat atgattgtat atttaatagt ataagtgaga ttgatagtgt
    20101 tgaaatttta tataactata atcttgaaaa aataaacttt acatcaagtg aaatcataaa
    20161 ttgtatatgt agagaatatg agtgttatgg tgaatactta gaagaaaaag aaaagcttat
    20221 gaatacattt aaagaaaaga ttattcaaat ctttgagtaa taggtcaatg ctgaagtggc
    20281 gctaatgcgc catttttcaa atatatatga attaagtaaa attattttgg aggaggcgat
    20341 ttgtatagag aaaacaggtg taattttggc agggggaaaa aattctagaa tgggtagaga
    20401 taaagccttt ttagagttac atgataagct ttttattgaa attgcaatag aagcatttaa
    20461 aaactttgat gagttgataa taatatctaa caatgaagaa ttatattcta aatacgatat
    20521 taaagtttat aatgatatag taaaagatgt tggtccaatt ggaggaatat atactgctct
    20581 tgaatatgca aagtatgata tagttacaat tgcatgtgat atgccatatc taaataatca
    20641 aatagtcgaa agaatagcta ataaaatgga tgataaaagt gtgatttcag tgacaaatgg
    20701 aaagttacaa ccattgtgtt ctggatataa aaagagtata ataaataaag tatctttatg
    20761 tataagggaa aatgatttaa agctcagaag ctttatagat aaaatagata aaagttatat
    20821 atactttgat gaagaagatt tatttttaaa tgtaaacact gttgatgagt ataaaaaatt
    20881 aactaaagtt taattagcta tggttgtaaa atagagtagg atttatatgg aggagagttt
    20941 atgaatttac ttaaatgcga ttcttgggca gtaatattaa ataatagcga taaagaaagt
    21001 aaagcatata aaatattaga tgaacttaaa aggaatatgt acaaagttgt tgctatagat
    21061 gaagagaaaa aacctattga aggaatagat gtgtatgaat gtttaaaaga tgttccacac
    21121 aatattgatg ttgtagctat tattgataaa caatctaaga tggatgtgat tttagaagaa
    21181 gtagagcttt tggatataca aaatatgtgg tttgaaaaag gaagctttag tgaaatgatg
    21241 attaaaaaga ctaaagattt aaaattaaat atagaatata atttaagttt atatgatgag
    21301 ttgactagat aaaattatat ttcttaataa taaaaatata attagttaat aaaacatatt
    21361 attttatagt atagattggt taataaaagt acagattggt taatgaaaca ttaaattaca
    21421 atatttgtta aaaaaattgt gagttacatg atataatgta ttaaatagga tactaaggag
    21481 ttgatatatt atgttaatag taactacaga aaaagtagaa ggtaaaaaga tatcaaaggt
    21541 tttaggatta gtgagaggaa gtacaataag agcaaaacat gttggaaaag atataggagc
    21601 aagttttaag aatcttgttg gaggagaact tactggatat aatgaaatgc tcactgaagc
    21661 aagacaaatt gccataggta gaatggttga agatgcagaa gctaaaggtg caaacgcagt
    21721 aatagcattt agactgtctt cagcttcagt tatgcaagga gcagcagaaa tgcttgctta
    21781 tggaacagca gttgttttag aagatgataa tagtattctt gaaaaataaa atataaatag
    21841 ttaaaaagag gcatctttta aaaattttat ggatgccttt ttttatttga aaaaactaat
    21901 ttgagaagaa attttaacta ttatgacaat aaaattaggg tgatattata taaataagta
    21961 aaattatatt atataatgta tggtatagac tttaaaaatt ttatttgtag agaaaaatat
    22021 ggacaatgtt ataataatta tagaaattaa aagtacttac attcattatg tatgtgacat
    22081 gtataattag ttttatattt aatacagttt tgaagtaata tcttcatttt gagaacgttg
    22141 gaataataaa aaatgtatta ttataggtga tataaataaa aaataaatat aatatgttat
    22201 attgctgata gaaaagagaa taaaagaaaa taggttttat taaaagagat ttttatttat
    22261 aggacttaat caatgtatag aggggtgaga acatatgttt aatgttgcaa ttataacact
    22321 tagtgataaa ggatatgaag gaaaaagaga agatataaca ggaaaaaagt taactgaatt
    22381 tgttgaaaat acaggagttt ataaagttac tgaatatgta cttataaaag atgataagga
    22441 aatgctaaag gaaaatatta taagactttg taatagtaat aaaatagatt taattcttac
    22501 aaatggaggt actggttttt caaaaagaga tataacccca gaagcaacta aggaagtgtt
    22561 ggaaaaagaa ataccaggtc tgagcgaata tatgagaatg aaatccacag aaattactaa
    22621 aaaggccata ctaagtaggg gtgtgagtgg aataagaaat aattctataa taataaattt
    22681 acctggaagt cctaaaggtg cagttgaaaa tctaagtttt ataattgatg ttttagacca
    22741 tggcatagaa gttttaagag gagaagctac agaatgtgcc actaaaaaaa gtgaatagta
    22801 tataatctag atagataaaa aatagacaaa gaggtagata aagtatgatt gataagtatg
    22861 gaagaaaaat agactacctt cgtatttcac ttacagataa gtgtaattta aggtgtgtct
    22921 attgtatgcc accagatgta aaatttgata aaaattatat aaatgaaaat ctaagctttg
    22981 aagactacaa gtttattata aaggctatgg ctgaacaagg tataacaaaa attagattta
    23041 ctggaggaga acctctttta tatcctaaat taaatgagct tataaaattt acaaaagaag
    23101 aatgtggaat aaataacata ggaatgacca ctaatgctat tggtctttct gatagaattt
    23161 ttgagcttga aaaatgtggc ttaaataaag ttaatataag tttagattct ttgaaggaat
    23221 ataagtataa atccataaca agaggaggaa acttaaaaga tgtcttaaaa tcgattgaat
    23281 cttgtttaaa tttaggtata aaagtaaagt taaattgcgt tgctataagt gggtttaatg
    23341 atgatgagct taaagatttt atgtttttaa cagttaaatc accaattgat gtaagattta
    23401 tagagcttat gccattaggt gaggctaata gagtttataa gaagggttat tttaatgtaa
    23461 aagaaatgat tgaaaaaata tatggtttat ataaagtcaa aaatgatgaa aaaagtacag
    23521 cagaatatta tatgtttaaa ggagctaaag gaagaatagg aattataact ccattaagct
    23581 gttcattttg taacacttgt aatcgtatta gacttacttc tagtggtgca ataaaattat
    23641 gtctacattc aaaagaagaa atagatataa aaccattttt acataaacca ttgttattta
    23701 gagaatctat gaaagatata ataaaacaaa aaccagaaaa acatcattta atagaaaata
    23761 aatgtagtga tacaaatagg cgtatgtatg aaattggagg ataagtaatg ttaacacata
    23821 taaatgaaaa agggtatgcc aagatggtgg acataagtga aaaagatgat actaaaagaa
    23881 cggccgtagc tacagctaca attactctta gtaaggaagc attagaaaaa gtaaaaaatg
    23941 gtcagataaa aaaaggagac gtattgtctg tagctcaagt tgcaggtata atgggagcta
    24001 aaaatacatc ttcaaacata ccaatgtgcc atcagattaa attagttgga tgtgatttag
    24061 aatttgatgt agatgattct atgtctgcta ttaagatata cgcaacctgt aaatctcttg
    24121 ggaaaactgg agtagaaatg gaagctttaa atgcatgttc tttagcagca cttacaattt
    24181 atgatatgtg taaagcagtt gataaaaaaa tggttataag taatatccat cttgtggaga
    24241 agactggtgg aaaatcagga gattttaagt tcgagtaaat taataatata ttgggttaaa
    24301 atttggagga aatatggcga aggtagtgtc aataaatata agtgagaaaa agggtgtaat
    24361 taaagttcct gtacaatgtg cagagctaaa aataaatcat gggatagttg gagatgcaca
    24421 tgcaggaaac tggcatcgtc agataagctt acttggaaaa gaaagcatag ataaaatgaa
    24481 aatgaaaggc tttgaccaat taaaatatgg agattttgct gaaaatgtaa ctacagaagg
    24541 gatagaagtt ttttccctgc ctgttggtac aaagttaaga atagggcaat gtgaagttga
    24601 agtaactcaa atagggaaaa aatgtcacaa tggatgtgaa attaagaaat tgacaggtga
    24661 ctgtgtgatg ccacgagaag gaatttttgt aaaggttcta aaagaaggaa ttataaatgt
    24721 gaatgattca atagatgtaa tctaatgaag tcactattaa aatataat
//
LOCUS       DAMJWC010000054        23711 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMJWC010000054 DAMJWC010000000
VERSION     DAMJWC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.054"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(537..1409)
                     /locus_tag="PC503_002637"
     CDS             complement(537..1409)
                     /locus_tag="PC503_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2528603.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1803..2381)
                     /locus_tag="PC503_002638"
     CDS             complement(1803..2381)
                     /locus_tag="PC503_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2528604.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2439..3155)
                     /locus_tag="PC503_002639"
     CDS             complement(2439..3155)
                     /locus_tag="PC503_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2528605.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3346..4431
                     /locus_tag="PC503_002640"
     CDS             3346..4431
                     /locus_tag="PC503_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2528606.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4586..5245)
                     /locus_tag="PC503_002641"
     CDS             complement(4586..5245)
                     /locus_tag="PC503_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2528607.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5462..6754)
                     /gene="lysA"
                     /locus_tag="PC503_002642"
     CDS             complement(5462..6754)
                     /gene="lysA"
                     /locus_tag="PC503_002642"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF2528608.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6772..7965)
                     /locus_tag="PC503_002643"
     CDS             complement(6772..7965)
                     /locus_tag="PC503_002643"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2528609.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHLVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8326..8943)
                     /locus_tag="PC503_002644"
     CDS             complement(8326..8943)
                     /locus_tag="PC503_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528610.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9113..10813)
                     /locus_tag="PC503_002645"
     CDS             complement(9113..10813)
                     /locus_tag="PC503_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528611.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11210..11773)
                     /locus_tag="PC503_002646"
     CDS             complement(11210..11773)
                     /locus_tag="PC503_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528612.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11932..12645)
                     /locus_tag="PC503_002647"
     CDS             complement(11932..12645)
                     /locus_tag="PC503_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF2528613.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12937..14601
                     /locus_tag="PC503_002648"
     CDS             12937..14601
                     /locus_tag="PC503_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF2528614.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLKQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14708..15607)
                     /locus_tag="PC503_002649"
     CDS             complement(14708..15607)
                     /locus_tag="PC503_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF2528615.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15634..16272)
                     /locus_tag="PC503_002650"
     CDS             complement(15634..16272)
                     /locus_tag="PC503_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2528616.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16609..17607)
                     /locus_tag="PC503_002651"
     CDS             complement(16609..17607)
                     /locus_tag="PC503_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF2528617.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17705..18280)
                     /locus_tag="PC503_002652"
     CDS             complement(17705..18280)
                     /locus_tag="PC503_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528618.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18596..18859
                     /locus_tag="PC503_002653"
     CDS             18596..18859
                     /locus_tag="PC503_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528619.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19296..19673)
                     /locus_tag="PC503_002654"
     CDS             complement(19296..19673)
                     /locus_tag="PC503_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2528620.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            20014..21126
                     /locus_tag="PC503_002655"
     CDS             20014..21126
                     /locus_tag="PC503_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2528621.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(21334..21810)
                     /locus_tag="PC503_002656"
     CDS             complement(21334..21810)
                     /locus_tag="PC503_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528622.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(22009..23634)
                     /locus_tag="PC503_002657"
     CDS             complement(22009..23634)
                     /locus_tag="PC503_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2528623.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALLNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
BASE COUNT         7900 a         3856 c         2486 g         9469 t
ORIGIN      
        1 ttacaaaagc tttatattct atgtcttaat atttataaaa actttatttt atttttataa
       61 agtattatat ttctaaaaaa gtttcccttt ccccaaaaat ggctacttaa aaaatcaaga
      121 tttcatacct aactactaat tctatgattt ttaaattttt caacttcttt gtcaaagtta
      181 aaataaaata ctaaaagaca catattatag tgaacaaaaa agatagaaat acatatttta
      241 atataatttt aataagatat tatatactta aatacaaata aaattaattt tataattgtt
      301 aattaaggaa atgatattgt ttagagaaat aaaaaaagca ctctccatga atggaaatgc
      361 tttctttaat aaattagttg acgtagtaaa gatgtattca gaatacatct ttatgttttg
      421 agtctcgaaa tatttatttg tattatttaa acgaaaattt attttttaag tgataatcga
      481 gtatttacta ataaggctat gattctcaat ttcatagcct tattaatata caaactttac
      541 tcatacacag aatatctttt ccaaatttgc tctaaatcat caaaatgctg tttaatatct
      601 tctttttcct tcatcccaac agatatagca agggcatttg aaatactaag agctggaact
      661 agagaatcta caaatgaagc catattactc ttaactagaa gagtgttatc tgcaagtgat
      721 gctactggcg caaataagct atctgttaat gatattacat gggctccttt ttctttagca
      781 taattgacaa tttgataaga tttcttagaa taacgaggga aactaatagc aactattaca
      841 tcttcttcat ttattcttac aatctgctca aaagcatctc ccatatccat tctaattata
      901 tgaacattgt caagtattat atctaagtaa aaacctaaat attgagctac tacaaaagaa
      961 ctcctcattc caagtatata tatttttctc gctcttaaaa gtttgttaga agcttcttta
     1021 aacgctctct cgtcaatttc ttctagtgta gaccttatat tatctatatc actttttaaa
     1081 actttgttta gtattgcaaa atcatcggaa taatcatgtg ccatttcaac tctttgtact
     1141 gtagttagtt tattttttat gagttcttga agtgcagctt gtaatttagg atatccacta
     1201 taacctaatg catttgcaaa tcttacaact gtagactcac ttactcctac ggtttcaccc
     1261 aatttacatg cagtcataaa tgcaacttta tcataattat ttaaaatgta ttgtgctata
     1321 agtttttgac ccttactcaa tctcgtatat tgagattgta tatttgatat caaatgttta
     1381 ctgtccttca tttcatttgt ttcttccatt tttttctcct tttagttata taaactattt
     1441 tgttttatta acactgtctt tttctctaaa aattttattt tttatctcaa tttcatctta
     1501 gtttttatca tagcttctta aactcataaa attctaactt ttctgtacct tatacttcac
     1561 atagtatttt cgattaaatt tattatacca tctttccttg cattttttaa tatttatcca
     1621 atatttcttt taaatttttc aatttttact catttaaaag ttatctatct tattttgcat
     1681 atttagatgt atattttgtt ttgagaataa actgttgtat acttattatt taaagtattt
     1741 ttaataggtc acactatata tattaactct taatacaatc ttgtcaagtt ttttagtatt
     1801 tattatgctt ttttcttttc aattaaaatc aattgtggtg ggttattgac ttgatttaaa
     1861 aacttagatt ctaaaacatt aaattcatct tgatttaaat tattgacaag gttatatatg
     1921 caatcttttt cttcttgacc tccatcatgc cctgtatata tggcaatgct tattactcca
     1981 ttttctttta acatttctaa acttaacttt atagccttta aagttgtatc tggtttggtt
     2041 ataattgaat gtttcgctct tggaagataa cccaaattaa ataaaacaca tgaaacttct
     2101 tcttttatat attgattcat tttttcatgc ccatcaaata tcaattttac tctatctgta
     2161 tatccttctt tctctagttt ctttcttgta gactttattg cttcttcttg tatatcaaaa
     2221 gcatatacaa agcccttttc tccaaccttc tcagctagat accttgtatc atacccattt
     2281 cccatagtag catcaattac tatgtcacct tcatttataa tattttctaa ataaaattta
     2341 tttatatctg taattttagt taaatacttt gcatatgcca taatactatt tctccctact
     2401 attaacttta tttcattttt tctcaattta tttttatctt attttattga ttttaaatat
     2461 tttatttcat cttctgttag gtatctatat tctccaactt tggtgtcttt taatactatt
     2521 ttccccacag aaatccttct taaatttaaa actggatgat ttatagcttt gcacattttt
     2581 cttacttgtc tatttctacc ctcatgtata gttatttcac acactgaata atttttttct
     2641 ttattttctt tagttaccct tattttggca ggtgccgttg tgtaatcttc tatttttagt
     2701 cctgtttcga attgtcttat ctcatcatca cttataattc ccttcacact tgccacatac
     2761 attttatcaa tttcatgctt tggatgggta agcttatatg ttaaatcgcc atcattagta
     2821 agtattaata aaccactagt ttcataatct aatctcccta ttggatatac tctttccctt
     2881 acatctttaa gtatgtctat tacactgggt ctattgaatt ggtcttttac tgtagttata
     2941 tatccctctg gtttatttaa tactatatat atataatttt cacttggttt tactttttta
     3001 ttatcaaatt ctactatgtc tttttcttca tcaatattaa aagataactc ttttactaca
     3061 cttccattta cctttattct tcctccaaga attatttctt ctgcttttct tcttgatgct
     3121 attccacaag aagctatata cttattaatt ctcatactta atccttcctt atcttaaatt
     3181 atgtgtgttt aatattttta tcaatgttaa ttttgctaca ttattatact atactagacc
     3241 ttaattaaaa acaagcaaaa aaattattta attttcctaa ataattgtaa tttcttttca
     3301 catactatta atatgtaata gctgactaaa cactatttta aggaagtgat tattatttca
     3361 aaggaaaata taaaatatta tttaatagtc gtgtttattg gaattttatt ttttaaattt
     3421 attaatactc catcagactt tatatctagt attgaaggat tcttaaagtt ttttagccca
     3481 tttttattag ctattttact tgctttactt ttaaatccac ttgtgatgct ttttgagata
     3541 aaattcaaag cacatagact tttagccatt tttttatctt atatatttat aggttttatt
     3601 ttagcctttg ccattaggtt attaattcca tcaatagcta atacattaaa tagattgata
     3661 aatgaaatgc ctatgtatac tgattatata gatagtttta tagaaaaaaa tatgtcaaac
     3721 atatattttc taaaaacttt aattcctcat atacaacata gtttagataa tttattaaaa
     3781 gaagcaagta attttgttgg taaaattcct aaaaacttct taatctatac acttagtata
     3841 tcttctatgc tatttaatat gacaatggga tttatactat ctatatacat tatatatgac
     3901 aaagaaaaaa ttgcattggg atttaagaga tttctatatt cttctactgc tagaaacaag
     3961 gcagataaca ttatagaatt ttttaggact actcatgata ttttctatga ttatttactt
     4021 ggtagaatat tagactctct tattattggt ataattgcat ttttaggatt tcaatttgtt
     4081 atcagaatag aaaatgcttt atttttagct tcaataatat tcttaggtaa tataattccc
     4141 tattttggtc cttttattgg tgcaatccct ccaatagcca tgactatatt atatagtcca
     4201 caaaaaacta tatgggtcat tgcatttcta tttatattgc aacaattaga tggaaatttt
     4261 atagaaccaa aagttatggg taatcaagtt ggtataggag ctatatgggt aatatctgct
     4321 attttggtgg gacaatctct atttggtttc ataggagttt ttctttcagt accaatagct
     4381 gctgttgtaa aaacttatgt tgataaatat atagataatc gtttacaata gattatctct
     4441 actgtgactt taatttttag tttaaaattt aactgctatt tattaaatta tttctcaaaa
     4501 aatatctctt agtaagaaaa aattgctaag agatattttt tataatatat aatttgttca
     4561 ttaaatttat gcatatattt tatacttatt gattatttga gttttgagaa tttccaccac
     4621 tatctgaacc accagtagta tcttgtggag ttggtgctgg tgttggatta ctattatttg
     4681 gcttttcttg attttgagaa gaactgttat tattgtcaga cttattacta tctgattttt
     4741 tatcattgtt tttagaacta gatttattat ttttactact tccactataa gaagatttcc
     4801 ttgcatctga ttcaactcta tacctatctt ctccagccgt atcttttgcc tttttctttc
     4861 tttgttcctc tgcttcgttt tgttcttttt ctaatttagt taactcttct ttctttttag
     4921 ttgcctcttc tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct
     4981 tgattgcacc ctcataattt tttaattctt caaactccgt catatttgac attctcatag
     5041 cttgcatata catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata
     5101 atgattccat agctttttta tagttatgtt tttctaaata tgtttttcct tgctctacta
     5161 aatttatttc atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata
     5221 ttaataaaat tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc
     5281 ataattataa agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacaa
     5341 aaaataagca gatatgctac gaacgataca ataaaccaaa aattaattta gagatacata
     5401 tcctagcaaa tctgctcata ataaacttta atatttaatt tttattatat acttctctat
     5461 tttatatctc taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat
     5521 ttccatcaaa tactgatacc actgctgctc ttggtatttt attataattt gaagacattg
     5581 aatatccata tgcaccagtt gatgttgtta taagtatatc tccactttta atatccatta
     5641 tgtttatatc tccaattaat atatctccac tctcacaaca ttttccagct attgttacat
     5701 gattcatagc ctcatgatta attttattca caatactaca ctcataacta gcttggtaca
     5761 acgaaggtct tacattatct gtcatacctc catctacact tacataaacc ctaacatctt
     5821 ttatatcttt tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc
     5881 ttcctggttc tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg
     5941 ctttagtgat tatggtttca caaaactctt ttatagtttt aggtttatct ccttcgctat
     6001 aataaacgcc aactcctcca cctaggtcaa tttctgttag ttgtatgttg aatttttctt
     6061 ttatttcttt taccaagttc atcattatat ccactgtatc tatgtatggt tctacatcaa
     6121 atatttgtga acctatatga gcgtgaagac ctacaagttt aatattttta tattcactta
     6181 atttttctat tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta
     6241 tctgtccagt ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaagt
     6301 atatctcttg agttttacct ttatcttcac ataatgcttc aagcaaatct aattcataaa
     6361 aattatccac tacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag
     6421 tcttattgtt tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat
     6481 ataactcgcc tcctgaaact acatctaaac acatttgttc ttcatttata agattacaca
     6541 tgtaaagagg taaaaaagct ttccctgcat aagcaacctt attttttccc tctctagcct
     6601 taaaatattc tatatattct ctacaatttt gtctaactaa agcttcatca aatacataaa
     6661 gtggagtttg atatttttta ctaagttcta aacaactcac tcctccaata tataattcat
     6721 cattatttac agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt
     6781 aaatacttct gctatttttt ctatagctac ttgcttatca tcagaattta tagcacaagt
     6841 tatacgaatc tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt
     6901 aaatacttta gcagcaactc cagaagtatt tttcatacca agacctacta aagaaaattt
     6961 agtgatatta ttatcaatca ctaaatgttc ttcatctgta tatttagata ctatcttttt
     7021 acattctccc aactcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg
     7081 tgcagtttgg cttatcatat ctacacttat acctatagtt gctatatctt caaataagct
     7141 agatatattt tcagctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc
     7201 taatcctgtt attactttat cctctaattt catgtctttt ccccctctta tatatgttcc
     7261 tttttctgta ccacatgtac gtccgacata gatttcaaca ccatattttt gtgcaagctc
     7321 tatacttctt gaatgcatta cttgtgctcc taaactcgct aactcaagca tttcttcata
     7381 ttcaatctca tcaagtttac tagcctttga atattttctt gggtctgtaa aataaattcc
     7441 atcaacatct gtatatatct cacattttcc atttaattta accgcaagag ctacagcaga
     7501 tgtatctgaa ccacctcttc caagagtggt tacatcacca tcttcgttga ttccctgaaa
     7561 tccagttact atcacgacat ttccttcatc taaactattt ttaattctgt ttacgtttat
     7621 atcatcaatt tgagactttc catgaagacc actcgttttt atatttaact ggtaagcatt
     7681 ataacttata gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat
     7741 catttcacca gtagacatta aagcatctaa ttccctctta ctaggttcat tactcaattc
     7801 ctttgctaaa gttatatatt catcagtgga ttttcccatg gcagatacaa ctattaccat
     7861 ttgtggattt tcttttcttc gttctattat attttctgct attgatttta ttttttcagt
     7921 atctgctact gaacttccac catatttttg aacaattata ctcatgcttt ctccccctca
     7981 agctaaattt tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag
     8041 accaagtaac cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa
     8101 gtccagaaaa tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc
     8161 aacgcttacc agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt
     8221 atttttaatt aatttattaa tatagtttta tcatattcta tataatattg caacaattat
     8281 tttacaaaat gtggcaaatc gatagttttc ttttctaaag ttagcttata tacaattaaa
     8341 tagtttattt aatcctaaat ctataaaatt tatgctatac tcattatcat atctctctaa
     8401 atcatttaat tcggatagat tatctggtgt aactaccaaa acgtttggta ctttaaaaaa
     8461 tggaattgta gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc
     8521 attatttaag tcaacatcaa ctaaaacttg ctttatatta ccaaattggt ctgtatattc
     8581 aataaataaa tcgtatttca catcatctac actaacattt cggtaaaatc tttttacatc
     8641 acaacctgca gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc
     8701 atctccctta aaaagtttac taccgtttaa atagtataca taagagaggt ctttataatt
     8761 ataataatcc acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa
     8821 agttttttta aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg
     8881 agactctgta acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt
     8941 catagtacat tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta
     9001 tgacattaaa tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta
     9061 taaaaattag ctatcactat gttaaatact attatcaatc tttttattta aattatacat
     9121 taccttgatt ttcagaatct ttggaatctg tattttcatc agttcctgtt ttttcttttg
     9181 cttttttatc ttcaaagttt gcaatattta ggttatcaaa ttctgacatt tctattacac
     9241 cagattcttc ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt
     9301 cgctagatac ttttgaagta gccctaaata ttatatcttt atttgaatct aaagttacat
     9361 aataattagt gttaccacct cgcacatctg ggcttattct tgtcactgtg ccttctaata
     9421 cctcatcttt taaatcatta tcaagtttta aatcattacc cttagattct aatgcatcct
     9481 tatagtttct taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa
     9541 cagatacaaa tgcaactctc ttaacaagac ccgccttatc ttttaatgat gatacatatg
     9601 ttggctgacc caatatatta tacattacag ggaacgtcgc ttcataattt ttttcttgaa
     9661 cattaccttc agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc
     9721 tagcttcttt tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg
     9781 aagatgttat acctgtatac caataagacc tgttatcatt gccataaact aatgatgtac
     9841 cttctgttgg tactaaaact cccttttctg atataacaga gtttaaaaat ccattaacat
     9901 aaacacccca gtctttaatt tggtctgtta caaagctttg tggttgtatt ctatccaccc
     9961 atttaggcgt gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg
    10021 ctattcctgt tgcatttgct cctccatagc caattttatg ttcatataaa cttacaaccc
    10081 aataaggtct tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa
    10141 taccatgtat gtataaatgt ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa
    10201 ctatctttat tggctttcca tctatttctt gaactaattg gacgtcttga ggattactag
    10261 ctgatacttt tacataacca cttgtaccac ttagagatgt tatccattta attatgtctc
    10321 tgtgaacaag aggcgctacc cagtacaact ctccatctac attttgtata tgaaattttc
    10381 ctaatttgga tacactccct attgcaggaa cttctccaag ctttttgtca cctaatttca
    10441 ttgccatatc ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag
    10501 taaatttact ttcagttact tttcccaata gttctctata tgattttgca tgaagtacag
    10561 gtgtagaagt tataaaggga actactacaa tatacacaag caaagctatt gctattgaaa
    10621 aattatattt agccatttta gatgctcttt catttctatc taacatcata tctagtattc
    10681 ctgctacaac aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta
    10741 caggtaattt aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa
    10801 gatatcgttt catttaatac tcctctctaa aaaatgttat tattactatt atatccatat
    10861 atttacaaaa aataaatatt tatcatattt attatatatt aagatatctt tatatattta
    10921 tagttctgct tattcaacta tatttaacat tatacgtgta tgtataaata ctttttatac
    10981 actgtttgtg ctatccatcc cgcacctaaa ggagtgggat ttttgcacta ttctgtatta
    11041 tatatatcca aaaatgttat aaaaatacaa atattagcag aaatttaaaa actgaagaaa
    11101 gtattctaac taagatttac aaattcttaa tcctatcgaa gttaaactac tatcttcagc
    11161 ctaattatct agcaatattt ttttatatga aaaactctaa atcaagtttt taaatgtttg
    11221 cgatttttga tacataagaa tgttgtctag aattatattc tgataataaa ccttcatact
    11281 ctaaggttaa gccagataaa ttataaaaat catttggcgt tacttcaaat gcttgtttat
    11341 ttaaaatgtc tatctcactt ttttctaaca tgtcagcaac aaaatttgaa catacatatt
    11401 tatattcaga ttgtctctga atattcatta gtaaatatat taatgccatt gtatcgtaat
    11461 agtaatcttc tctataatca ctaattaatt ttatattttt atatagattt tcatattgta
    11521 aattatctac ttctaacgaa tataccctac acacagtgtt ttttcttata gcatataatc
    11581 cttgatttat attttcttca acaaatcctc caataaatgg attccttgga tttagccttc
    11641 caaaagaata cattggtttt agattttcat ttaatgatat tgacacatgt gtatacagct
    11701 ttttacttat attccttatt aagtaagata atatagttcc tgtatatgtt gttacaatat
    11761 agactttatt catcatttcc ccccaatcta gtaactaaat aatattatac acttacaatt
    11821 taatatcata agatattcta acataataaa tgtggtttta caaattttga ttttaaggta
    11881 ctttaatatt atataatata ataaaaatat aaatataagt tttctatatt tttaaccaac
    11941 agatgttttc ttcaaattaa tcagatgatt tagtatatct tgaacctttc cagagtcctt
    12001 taaatatcct aatgccccat ttatttgtga ttttaaatct atttctactt ccatatccaa
    12061 atcaacattt ccttttttta tagatatatt tttaagtgtt attgggtaaa gataactttt
    12121 ttccaaagta atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa
    12181 tattttttct agcattttat cacttagttt aaattttcca attttcacat tctcaagact
    12241 tacaactaag tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac
    12301 caaaccaaat accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa
    12361 attattttca agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa
    12421 ctcttcctct gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat
    12481 agaatttata tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga
    12541 actaacatca tatctttctt ttggtgtcaa gatatataca acaattcctg caagtactaa
    12601 aacaataaca attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac
    12661 aaatctgtca tcagatttaa aataaattta gataactaac ttcacataat attcttaaca
    12721 atatacatac tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa
    12781 taaactgtaa aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta
    12841 cacctttatt tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt
    12901 ctgtattata atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct
    12961 aactttataa agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata
    13021 actcgttttc cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt
    13081 cttaattttg gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca
    13141 aacccattaa aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta
    13201 ggatttgatt ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga
    13261 gctttaatac taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg
    13321 agagaatatc gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact
    13381 attgaagaaa accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa
    13441 aaaacattaa gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt
    13501 atatatagaa tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct
    13561 atgtatgctt ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt
    13621 actttagagt ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg
    13681 gaaaatatac ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt
    13741 aaaaggaaat taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt
    13801 gttcctacaa tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc
    13861 tgtagtgaaa taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat
    13921 ttcctaagag aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta
    13981 aaacttatta taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat
    14041 gctaaagatg aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa
    14101 caagatgatt ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa
    14161 gtccgtttaa aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga
    14221 aatgtagttg aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca
    14281 ggacgtaagg taaaatctac aatacattgg gttgatgcta aatcagctat accatgtgaa
    14341 tttagattat ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc
    14401 ttaaaacaaa taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag
    14461 ataaaagatg ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata
    14521 gataataaat atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt
    14581 tcttttaaac caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac
    14641 ttctactata aataaactta gttagaagta attttttatt tgagtcttca tcatttactt
    14701 taaatgatta acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt
    14761 ctatgttaag aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt
    14821 cacattctat atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat
    14881 ctaaataatc acctctaagc acacttatca aaactggtat tgattttggt attggcattc
    14941 ctttaaaaat aattacatcc aaatatccat catctatttc agccttatat gctagattta
    15001 tatttcctgc tgttttgcca ttaaaaatca acataagata catatctcca tcataataca
    15061 tttcctcaga agatactttt atcttaaatt tcctcatata caatgcttct tctattccct
    15121 ttatataata agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata
    15181 catccgtaaa cataccagca cttgcaacat ttataaagta cttattattg actttcccta
    15241 tgtctatttt ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg
    15301 aaatttgaag agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa
    15361 tttttatgtc taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag
    15421 ctatcaatat gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt
    15481 taatagttaa tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag
    15541 tgtctaaatt tgataatatc tttttttcac ctgaattagg attgtatata agttttactt
    15601 ttttcattat ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa
    15661 aatcacatgt attctttctg gtgttaattg tctttttata agtgtataac tacagcatat
    15721 tcttcctgga cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact
    15781 taatctttta caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac
    15841 atctttaact attttattta ctcctgctat aactattact ttatcaggtc catatatcat
    15901 agcagcaact ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc
    15961 attagtactt gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc
    16021 ttctggtttg atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc
    16081 aatcactcct gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt
    16141 aactatttct tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat
    16201 attattgttt tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa
    16261 attttgatcc attttaactt cccccttatt tttaatatgc acttaattat ttataaactt
    16321 tattttcttt ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat
    16381 agttttacat aattttttcc aaaataactt actcaatcaa aaaaggaaag tagatgtact
    16441 attctacttt ccctatattg tatgtagtat ttattgccta aaatctatat attaattata
    16501 tgtttcatat tatataatat cacagttaat taaaatgtaa tactatcttc tttttaaaca
    16561 tataaattgt attattaaat ttaatatatc caacttcaat aaatcttatt aatttgatga
    16621 agaagatgct atagctgcac ttgttgctgc cattacacat gcaatttgaa tagcaacaac
    16681 aatatttaaa aatatattat tagttataga gcctatatta ttctcatttc gtatcaaatc
    16741 tgcataaatt gaagctacaa tagcagaact aatcattact ctattacttt ttcctaaaga
    16801 ccaatttcca aagccttttt cttctttaag tttatttgaa acatttttta tctcttctat
    16861 tatttcatct tctctataat ctaataatga aattgctcct attattggat atccataata
    16921 attcatttta caatcatttt ctttaaatgc ttttttaagt tcaatagtct ttttacattt
    16981 aagcatagtt ctatcatcac taaataaaag aatttgggat aatgcttgta aatcatttcc
    17041 tttataaaaa ccattttcat ttagaaattc ataacatttt tctatgtatt ctaaatcttc
    17101 atctaaattt tttgaatgaa ttgcaataag tgctatatta caatagtcat cactagaagt
    17161 tagaaatgga tgttttttcc tcatgtaatc atatattatt ttcatttttg atatacatgt
    17221 aagataatcc attttctctc tattttcata aactattgat gctgtaagtg gtaaatatgt
    17281 atcgccccaa aacttttcac ttttaagttc tttgtatata tctaaaatca tcttaaaact
    17341 actttctgga tttgattcaa acgaaagtag tgttgccata taaaacatat tatatcctct
    17401 aaaattagag aataatccag tatttttttt aataagctct attcgttctt ccactaatct
    17461 aggacttatt ctcttgttct taagggtaaa tgcaagtgca caactatgtt gtatcaatcc
    17521 catttgccaa gaacctttaa cttcatttaa tgctttgtaa ttttctatta ataagtttac
    17581 ttttccattt ataaacgatt gttccatatt gccctcctag taatatatct cattgtacta
    17641 atagttttat atttattata tatatattaa atactacaat caatacatat tacttcaaag
    17701 aacatcattc ttcaacaata atgtagcctt ttttgtaatg tcttcccata ttattgactc
    17761 tatcatagta ctctgattca ctttcattac tccatttggg cacaaataca tctattgcat
    17821 tagaattact aaaatactta ctagaccccc tatccataac agtttttaat tttccatcta
    17881 caataatctt agttccaaaa cttaagtgat tgtttgctac aaaaccatct tctaaatcat
    17941 ctcctgtagc agttatcgct ccatatccat tttcttgatt aagacttgtg taataactaa
    18001 cttcaaaagt tataggtact aacttcttta ttttaatacc taactgattt tgtagtttct
    18061 ccttttgtac tttcaactta tactcatcac tatttttata atcttccata ccttgattat
    18121 acttggaatt aaagctttta cctgacttta ctatagtatc tatatttact atagattctt
    18181 tacaatgatc tgcatctatt tttgtttctc catttaccaa taatggagtt aaacatacac
    18241 tacatacaac acatgtaatc aatgcttctt taagcttcat aaattccccc cttattattt
    18301 tgatatatta gcatatttaa tattatatgt ctacatttag atttaaatac cacacccatt
    18361 tgctttaaga agttgtctta tatttaattc accttaaaca cttataaatc ctctatctta
    18421 gaatcatata gaataaagct tttatcttta aatatttttt attaatcttt taaaatctaa
    18481 aactacttta tctaattttc tcttttttag aatttaagaa ttaaaattct ataattttaa
    18541 aacatattga atttattttt ttgagatgat ataattttct taagaggtgg ttgatatgat
    18601 aaaaaataca aaacaaatta cagtagaagt taatgaaatt ttattacaag aaatgtctaa
    18661 gataactaat gacgaaaata atattttgac agatttgata aatgaatcaa ttgtaaatta
    18721 tattcttgaa aacaaaaaac ataatattga aaataaagat ttagaagaag tgattaaatt
    18781 ttacaaaaaa gaaaatactg aaaaacctaa aagtgcagca agagctatag ctgaagcaaa
    18841 aactcatact ctgtattaat caaataaaaa agttcctaaa aactaggaac ttttttatat
    18901 taataattat taatatatct caatatttat ctcaaatcta tcaatataag catgtttaat
    18961 acaatctatt gtatacttat cttaccctag aaataatcaa aacaaaaata aaattatgcc
    19021 ctttatatct aaaacaatta atttacatga ttaatataca aaaattctga cttttaaatt
    19081 cgtatacaat atcaaactaa aataatatta atgacaaacc caatataaat taaattcaaa
    19141 caggtttgat tttacatcaa acttattgta ttaatattaa ataacaagac aaaaatattt
    19201 ataaaaatca caaattttac ataaaacttt atatttgatt catttaacta attattgtaa
    19261 aaactattta ttttatgata attaactaca ccaaattatt catctttttt aatatcctta
    19321 acccattttt caacagagtt caattcttct tcatttaccc cctttttgaa caaggatttc
    19381 ataaaactct caatagaact tccatgcata ttatctaaaa aagtttttgt ttcaaaatgt
    19441 aaatactctt cttctccaat aagaactgta taatgtgtat gtctatcaat ttttcttgca
    19501 cttaagaatt gcttatttac taatcttgat aaaagtgtta gtgttgtagt ttgcttccaa
    19561 ttatatagtt tttccatagc ttcaatgaca tcttttgatg ctactgtaaa atctgaactc
    19621 caaataaatt tcatgacttt taattctgct ggtggtatct tagtaatagt catatgattt
    19681 tacactcctc tcaaacttct acataattaa atactatatt aatagacttt tcgagtcaaa
    19741 ggttttattt aaaatatctc atccaaattt attaatacaa aaaatttata tttttattca
    19801 aaattaaaca cacaatctat taatataaag ataaatatct attctataag tataacagat
    19861 tatcaaatta aaattctaat atttgacata atatatacat tttttaaata aatatataca
    19921 atgtattaaa atgtatgcaa ctctatttca aaattatttt gtgatatata tatgttataa
    19981 taaatgtata aaattttgat tggtgggtta tatatgaatg catttattag aaaaagaaat
    20041 aaaaactatg ttgtttacct ggaatttgaa gatgaaaaga caggtaaaag aaaacaaaaa
    20101 aatatgggta cttttgataa aaaaagggaa gcaagtaaaa gactaaatga ggtaaaagaa
    20161 agcttatata atgatggttt tttagtacca agcgaaatta cagtgtcaga atttctatta
    20221 gattttctaa ataaatatag tgaaaatata tctttagcta catataataa ttatgttagt
    20281 atttgtaaga attacattaa tccatctatt ggaaaatata aaatacaaga cttacatccg
    20341 gttcacatac aaaactacat agataaacta tcttataaac taaatcctca atcaattaag
    20401 attcatataa atatattgaa acttgcaata aaaagagctt atagactcaa attaataaaa
    20461 gaaaatgtta tggatagtat agaggctcca agatataaaa aatttaaaaa tgagatttat
    20521 gatagagaac aaatgataaa attattagat ttagcaaaaa atacagaaat ggaattacct
    20581 attaatttgg ctattggatt aggtcttaga atttcagaag ttttaggtct aacttgggat
    20641 aatattgatt ttgaagaaaa tacaataaca gtaaataaga taacttcccg aattaatggt
    20701 tctgttattc tcaaagagcc aaagacagaa agctctgtta gaaaaatatc ttctcccaaa
    20761 gaattaatgt ctttattaaa agaatataaa ataaaacaga ataaaaattt attaaaatct
    20821 tccattagaa ataataataa tttgttattt ttcaataaga aatgtgaacc tattgctgaa
    20881 gatgttatga gtaaaaaatt taaaagattt ttagaaaaga atgaattacc tcatattaga
    20941 ttccatgatt taagacactc acatgttact ttacttataa attctaaagt acctataaag
    21001 gttatatccg agagagtagg acactcaaat ataagtacta ctctaagcgt ttattctcat
    21061 gtacttaaag aaatggataa agaggcttct gacaaaattt ctgaaagttt atttaatgct
    21121 aattaatatt aatttatctt agctttaaat tagcttagct tattgagata gattcattaa
    21181 tattaaatgt atctatctca aattaataac tacttaaata atctgtttta ttttaattta
    21241 tcgcctcagt tattatactt ttttacgaaa aattatactt tacaataaaa aagatattcc
    21301 cttatagaaa atatcttttt aaatactata ttattatata cttgctaaca ttggaatatc
    21361 taacatcttc ttcattacat catctacttt ttttgcttta tattcattgt atccaattaa
    21421 atatcctttt tcatatgaac tttttaaaat ctctttttca tataaattat cagatttggc
    21481 ttctgtgaca cttaaattat aaagcccttt acacccatct tcataacctt tattataccc
    21541 tttttctgca aaatagtttt tatgattttt ttcgttatgt actgaagata ttgttactcc
    21601 agaattttct tttgtactag cataaggaca aaaaccttta ttgtgttgat gtgctgaatg
    21661 tcctccacaa taataacgtg ttaactctga tttattttta ttatgatgac ctcctgatga
    21721 attatgccct cctgagtgag catatgaaaa attccctaca ctaatcatag ctaaactaat
    21781 tactacagct actaaccttt tcttaaccat aatctattcc ccccaaaatg ttatatattt
    21841 ttattatatc atctactata ttatatttaa attcttaata tacaaaatat tactctattc
    21901 tgctaataaa catgtttaaa caatataaaa aacctcctaa tatttgatta aaaatttaca
    21961 cactcatgca tagcatgtct caaatattaa aaggttttat actaataatt atttatcttt
    22021 tccatacatt ttagctaatt ggtcttgtat ctctttactt tctaaatact catcaaagtc
    22081 catttttcta tccattattc catttggagt tatctctata attctatttg ctatagtaga
    22141 tataaattca tggtcatgag aagtaaataa aagcactcct gggaactttt caagtccttt
    22201 atttacagaa gttatacttt ctaggtctaa gtggttagta gggtcatcta atacaagtac
    22261 atttgcattt gaaagcatta gcttactaag catacatcta accttttctc ctccagatat
    22321 aacttgagct tcttttaatg cttcttcacc tgagaataac attctaccta aaaatcctct
    22381 tataaaactt tcactttttt cttcagagaa ctgtctaagc cagtcaacca aagaatattc
    22441 tactccgtca aaaaacttat tatgattttt tggaagataa tcttgagaag tagttactcc
    22501 ccatttatac tctccactgt ctggttcaag ttctcccata actatgttta aaagtgcagt
    22561 agtagctatt tcatctccca taaatactac tttatcatct ctatccaatc taaatgacac
    22621 attatcaaga accttaaccc catctatagt tttagttaaa ttgtgtactt ctaaaacttc
    22681 attcccaatt tctcttgcag gtgtaaatcc tacatatgga tatcttcttc ttgatggttg
    22741 tatatcttca acttctaatt tctctaactg tttctttctt gatgttgctt gtttagcctt
    22801 tgaagcatta gaactaaatc tagctataaa ttcctttaat tgagctatct tttcttcagt
    22861 ctttttattt tggtccttag ccaattgtaa agccaattga cttgactcat accagaaatc
    22921 atagtttcca acgtacattt gtattttacc aaaatctacg tcaactatat tagtacatat
    22981 ttgatttagg aaatgtctat catgtgatac tattataact atagattctt ctaaatccat
    23041 tataaaatta tttaaccagt ttattgattt aaaatctaag tggtttgtag gttcgtccat
    23101 taatagtatt tcaggcttac caaaaagtga ttgtgctaac aataccttaa ccttttcccc
    23161 accaactagt tccttcattt gtttgtaatg catatctttc gttatgccaa gacccataag
    23221 tattttctca gcattagttt ctgcatccca tccgtcaagc tctgcaaact caccttcaag
    23281 ttcggcagct tttatcccat cttcttcatt aaagtcttcc ttcatataca atgcatcttt
    23341 ttctttcatt atgttccaaa gtctctcatg acctcttata acaacattta aaacagtttc
    23401 ttcttcatat tcaaagtggt cctgttttaa aactgacatt ctttctttat cagttataga
    23461 tatactacct gtattaggct ctatttctcc tgataatatt tttaaaaaag tagattttcc
    23521 cgcaccatta gctcctatta ttccatagca attaccttta gtgaatttta agttaacatc
    23581 tttaaatagt tccttatcac caaatctaag tccaacacct gtaacttgta acattaatat
    23641 attttccttt ctttttgctc ataatttatt ttatcataaa actttgataa catttttatt
    23701 atatattatc a
//
LOCUS       DAMJWC010000055        22937 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMJWC010000055 DAMJWC010000000
VERSION     DAMJWC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.055"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            376..1653
                     /gene="hflX"
                     /locus_tag="PC503_002658"
     CDS             376..1653
                     /gene="hflX"
                     /locus_tag="PC503_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2528624.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            1886..2383
                     /locus_tag="PC503_002659"
     CDS             1886..2383
                     /locus_tag="PC503_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2528625.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            2433..2957
                     /locus_tag="PC503_002660"
     CDS             2433..2957
                     /locus_tag="PC503_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2528626.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            3269..4633
                     /locus_tag="PC503_002661"
     CDS             3269..4633
                     /locus_tag="PC503_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF2528627.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            4772..5938
                     /locus_tag="PC503_002662"
     CDS             4772..5938
                     /locus_tag="PC503_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2528628.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            6055..6837
                     /locus_tag="PC503_002663"
     CDS             6055..6837
                     /locus_tag="PC503_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF2528629.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(6956..7609)
                     /locus_tag="PC503_002664"
     CDS             complement(6956..7609)
                     /locus_tag="PC503_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528630.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(7633..8997)
                     /locus_tag="PC503_002665"
     CDS             complement(7633..8997)
                     /locus_tag="PC503_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2528631.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            9655..11085
                     /locus_tag="PC503_002666"
     CDS             9655..11085
                     /locus_tag="PC503_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528632.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            11188..12291
                     /locus_tag="PC503_002667"
     CDS             11188..12291
                     /locus_tag="PC503_002667"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2528633.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            12306..12542
                     /locus_tag="PC503_002668"
     CDS             12306..12542
                     /locus_tag="PC503_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2528634.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            12559..13608
                     /gene="vorB"
                     /locus_tag="PC503_002669"
     CDS             12559..13608
                     /gene="vorB"
                     /locus_tag="PC503_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2528635.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            13610..14350
                     /locus_tag="PC503_002670"
     CDS             13610..14350
                     /locus_tag="PC503_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2528636.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            14353..14892
                     /locus_tag="PC503_002671"
     CDS             14353..14892
                     /locus_tag="PC503_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2528637.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            15016..17115
                     /locus_tag="PC503_002672"
     CDS             15016..17115
                     /locus_tag="PC503_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF2528638.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMEKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(17382..17897)
                     /locus_tag="PC503_002673"
     CDS             complement(17382..17897)
                     /locus_tag="PC503_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF2528639.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(17989..19200)
                     /locus_tag="PC503_002674"
     CDS             complement(17989..19200)
                     /locus_tag="PC503_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2528640.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            19876..21318
                     /locus_tag="PC503_002675"
     CDS             19876..21318
                     /locus_tag="PC503_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2528641.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            21360..21713
                     /locus_tag="PC503_002676"
     CDS             21360..21713
                     /locus_tag="PC503_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528642.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            21904..22725
                     /locus_tag="PC503_002677"
     CDS             21904..22725
                     /locus_tag="PC503_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2528643.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
BASE COUNT         8822 a         2623 c         3923 g         7569 t
ORIGIN      
        1 atgcaaataa ctacttaaat ttaagaatag ggttaaatat aaaatgataa ttacatataa
       61 gttaattaaa ctaatgtatt tttaatatat atttagaatt ttaatccttc ttatgatata
      121 agtagcttgt tttgtattac ttagatttgt aaggagtttt tttattgaaa aaactgcata
      181 atatatttgg gaggaggtgt aagaaagtga ttttttatat aagattgaga aaataatgca
      241 cgattatggt tattataata gtaaataaga agtgtcattt aaggataaga taaaaagcaa
      301 aattcttgat gaatttaatt atagagccat aatctcgtgc tatagattaa ataaaaaata
      361 gcagataagg agaatatgga tatggcgaaa aaaggaataa cagtaggatt aaacataaat
      421 aataaatctg aggactttaa tgaactaatg attgaacttg aaaacttatg ttcagcatgt
      481 gatattgatg ttgtagggag tataactcaa aatgcaaagc aggttaatag agcattttac
      541 attgggacag gtaaagttga ggaaatatta aacttaataa agaaagaaaa tatagagata
      601 gttatatttt acaatgaact ttctacatca caactaaaaa atcttgaaga aaagcttaat
      661 tgtgaaatta tagatagaac ggcattgata cttgatatat ttgcacaaag ggcaaaaact
      721 agagaagcta aacttcaagt agaagtagca agtttaaaat atatgttacc aagacttata
      781 ggttcaaatg aaaatttagg acgtcaaagt ggtggagttg gtactaaaaa tagaggttct
      841 ggtgagaaaa aattagaact tgaccgtaga agaatagaag aaaagataac atctttaaat
      901 agggagttgg atgatttaaa attccaaaga gaaactcaaa gaagtatgag aagaaaatca
      961 aatcttccaa atgtagctct agtcgggtat acaaatgctg gtaaatcttc aataatgaat
     1021 aaactagtag atatatttaa aaactctgaa gaaaagaaag tgtttgagaa aaacatgtta
     1081 tttgctacac ttgaaacttc tgtcagaaat atagttcttg caaataacaa agaattttta
     1141 ttatctgata ctgttggttt tgtaagtaat ctaccacatg acttagtaaa agcatttagg
     1201 tcaacattag aagaagcatg tgaggcagac gtactgttac atgttattga tatttcaaat
     1261 ccaagctata aaagtcatat taaagtgaca gaagatactt taaaacaaat aggtgcagat
     1321 ggtataccta tgatacatgt gtataataaa attgatttaa tagatgtaga agtattggat
     1381 agaattttag atagtatcga taaagaaggt atatttgttt cagttaaaaa agatataaat
     1441 atagataaaa tgataaaatg tatttgtgat agcatattta aagattatgt aagatgtaag
     1501 ttcttaattc catatgataa aggtcatgta gtttcttatt ttaacgaaaa tacgagcatt
     1561 ataaatacag aatacagaga agatggagct attttagatg tagaatgtag caatatagaa
     1621 tataataagt ataaaaagta tgctttagag taaattttga aaaacttatt atagcctaaa
     1681 atatatttaa tttataattt attataaatt gattgtaaat atgattttat gaaacggtat
     1741 agccataatg ctatgccgtt ttgccgttta taataaaaat aaatttattg acataatagt
     1801 aactaattac tataatataa agtaattagt tactatttaa aattatcaaa aaattaaaat
     1861 ctaagataaa gagaagtgta taataatgga tgcagaaagt ttaatgaaaa aatatatggt
     1921 agatgatgat agtagaaaac aagctatatt tgcaagtata tttgtaatgc aaaataaact
     1981 tcaaactaca tgtgataaat tagacccaga attaacaatg aaacaatggt tacttttagc
     2041 tattgcggac tctgtagatg aaactcttac attaaccaaa cttggagaat taatggggtg
     2101 ctcaagacaa aatgtaaaaa aactagctat tgctttagaa aagaaaggtt ttatacaaat
     2161 tgagcagaat gaaaaagatt caagagctat ctgtcttgtg acaaaagata gagtgcaaga
     2221 gtattctaaa aaagtaagag gtatgcagga aaaagtatta cagcttttat ttgaagattt
     2281 tacagagaaa gaagtggaac agttattttt tggaattatg aaattaagta taggaattga
     2341 aaatgtgaaa aattatgtag aaaataatga cgttggagaa taagcaagta tcaaatcaac
     2401 tttgtatgac atcagagagg gggataattt atatgaaaaa tgtagtagtg atttataaga
     2461 gtaagtatgg ttcaacaaaa aaatatgcta aatggctttc agaattattg tcttgtgata
     2521 tttttgaaac taagaatatt aatatagaaa aggttatgaa gtatgatacg attattttag
     2581 gaggaggtct ttatgcttgt aatatagcgg gaatttcttt cttaaaaaaa aattataaag
     2641 aattgcagaa aaaaaattta gtagtatttg gcgtaggagc tgctccatat gatgatgaag
     2701 taataaagaa attaagagaa gtaaatttta aggatgaatt aaacaaaatt ccttgctttt
     2761 attgtcgtgg ggcatgggat gagacaaaaa tgtcttttat agattatact ctttgtagtt
     2821 tttttaaaaa atctatagct aaaaaagaac gtcaaggtct taaaccagca gaagcacctt
     2881 tattgtctgg agaagccttt gattggtgta ataaagaaaa tttaactcca atacttgatt
     2941 atataagaga actttaagag gtatatattt gtaattattt attatctaaa gttagatttc
     3001 atagaaactt actagacatt atttataaaa taatattatt aaagatggat aatttaattg
     3061 tttcaataag gttataattt taaaaaatgt ttattttaaa ataaactatt ttataagctt
     3121 acttatactt aataaggggc tttttttatt ggaagattta tgttatattg agatgaattt
     3181 attatgatat aaaaaataat gttaggataa atttaaatct ttttctaaaa atgtattagt
     3241 ataattctta aagaaaggat ttttaacaat ggatataaaa gagttagtta aaatgcaaag
     3301 aaaatattat aatacaggta aaacaagaga tatatcgttt cgtatagaac agttgaagaa
     3361 acttaagtta gttgtatcac aaaatgaaga aaaaatactt ttagcactaa agaaagattt
     3421 aaataaatcg gattttgaag gttttatgac agaggtaggc atgttttata gtgaattaaa
     3481 ctttgctata aagaatataa gaaaatggag caaaataaaa agagttaaat caagtatggt
     3541 taattttcca tctatatcca aagttgttcc acaaccttat ggtgttactc tcataatgtc
     3601 accttggaat tatccatttc aattagcact tataccatta gtttggtcat tagcagcagg
     3661 gaattgtgtt atattaaaac cttctgaata ttctgtgtca acatctagtg tagttaaaga
     3721 catagttgaa gatacttttt caaaagaata tgttgcagtt gttcaaggaa gtcaagaaga
     3781 aagtgaaaag ttactattgg aaagatttga ttatatattt tttacaggaa gtactaatgt
     3841 tggtaaaata atcatgaaat cagcatcaga gcatttaact cctattactt tagaacttgg
     3901 aggaaaaagt ccttgtatca ttttaaaaga tgctaatata gaccttactg ccaaaagact
     3961 tacttgggga aaactaataa atgcaggaca aacctgcgtg gctccagatt atgttttagt
     4021 gcatgaagat agaaaaaatg agttaataga gaaaataaaa tattatacta ataagtattt
     4081 tggggataat gcatgtaata atgagcaatt tcctaaaatc ataaatcaga gacattttaa
     4141 tcggatatta tctcttattg ataaagataa gatagtctat ggtggaaatt ataataagga
     4201 gacattaaag atagagccaa ctatagtaga caatgttaat tgggatgata atataatgaa
     4261 ggaagaaata tttgggccta tatttcccat tttaacatat aaagatttag atgaagtaat
     4321 acaaaaaatt atacaaatgc caaatccatt ggcactttat atttttacaa aaaataagta
     4381 cctagaaaat aaacttttag aaatgattcc agcaggcgga tgttgtatca atgatacagt
     4441 tactcatata gctacgaatt acttaccttt tggtggtatt ggtgaaagtg gtatgggctc
     4501 atatcatgga aaagctggat tcgatacatt tactcactat aagagtgtgt taaaaaaatt
     4561 aaatttggat gtccctatta gatatgctcc atacgataat aaattaatta aggttcttaa
     4621 aaagataatg taggttatat tgtagaataa taaatataaa taaaattgag tatttgtatt
     4681 ctgaatatat tttattttta atttggtata tttgttataa aagtggtgat tttgtgataa
     4741 aatttaatta tatagaaata aggaggaaaa aatgaaaatt aattggaata caaaatacac
     4801 aacaatagca atttatacat ttataatagc tgctagtagt attatatttt atctagtatc
     4861 atcacaaatt gatgtatttt ctaataattt agatgctata tttacaacat tacaaccttt
     4921 tataatagga tttgctattg catatcttct taattttatt ttaaagtttt atgaagacag
     4981 aatttttata aaaagtgaga aattaaaaaa actaaaacaa agttcaaaaa gaggcttggg
     5041 tcttttatta acatatgcaa cagctacatt gatactttac ttatttatgc atttcgtatt
     5101 gccacaagta attgagagta ttgttggact agcaaatgat atacctatgt atgtaaacaa
     5161 tgcaactaag cttattgata aattaatgac tgatttaaat cttgatgagc aatactttaa
     5221 tttggcagtt gataagtgga atgaatttgt tacatatatt ataaagtttg taacagattt
     5281 aatcccaata ttaggaagta tgttaaagaa tgtagcctct agtatatgga atattgtact
     5341 aggattaatt gtttcagtgt acttattaat tgataaagaa aaattctatg gattaagcaa
     5401 aaaaataact tatgcagtat ttacagaaaa acaagctgcc agaattttag aattaactca
     5461 tagaagtaac tatacatttg gaagattttt aggtggcaaa atattagatt cattcattat
     5521 aggtattcta acatttgtaa tacttacgtt agttaaaatg ccatatacat tattaatatc
     5581 agttataatt ggtattacaa atattatccc tttctttgga cctttatttg gagctatacc
     5641 atctacgcta atagtgatgt ttgtatctcc tataaaagct ttctggttat tgttgattat
     5701 attaataata caacagatag atggaaatat tataggacct aaaatacttg gagattcaat
     5761 tggtatatct gcattttgga ttttgttctc cttattggtt gcaggaaaat tattaggttt
     5821 tattggaatg gttataggag ttccaatgtt tgcagtaatt tattctataa ttaaggatat
     5881 tgttgaaagt aaattggaca aaaagggatt accgacagat acttccgatt atatgtagct
     5941 aaaaaatatt atgtataatt aaaaatatat aaattaagca atatttaaag cactgagaaa
     6001 gttaaactct tggtgctttt tagatataaa attattatag aagaggtgtt ttttgtggca
     6061 tttatagaat gtaaatttaa atctaaatat actggaggag aaactgatat aattgtaatt
     6121 ttgcctgtag caaatggaaa agaacttttt agtggtaaag agatatatga ttttgaaggt
     6181 aaatttaaaa cattatactt atttcatggt ttagaagatg accaaagctc atggattaga
     6241 tatactaatg tagagcatta tgctaaaaat aaaaatatag ccctagtaat accaagagta
     6301 gaaactagtt tttatactga tatggcgtat ggacaccaat attttacttt tgtaagcgag
     6361 gaattaccta aatttgttag agctatattt cctttatcag ataaaaggga agataacttt
     6421 gtagctggta tgtctatggg gggatatgga gctttaaaat tagcgctttc aaaaccaaaa
     6481 gagttttcgg cagttgcaag tttttctggt tcgcctgata tgattcatga gttagaaaat
     6541 caacaaatag aaaccaatgc agacattcta tttcacgatt ttggtagacc agaagacgct
     6601 agaaatagtg agaatgattt actttacata cttaagaacc ttaaagaaag aaatgaagat
     6661 attcctaaaa tttatcaatt ttgtggtgat agagattttt tatataaaaa taatcagatg
     6721 tttaaaaaat atgcagattc tctgggtgta gatgttgaat atgaagagtg tgtagggggg
     6781 catgaatggc gtctttggaa tttatggata aagaaattta tagatataat tggatagtac
     6841 acttatggta ttaacaggta tactataaaa tatctttaaa tatgataaag actgaaatcc
     6901 taaaatcaaa ttatgatttt aaaatttcag tctctaagaa tttaataaaa ttttattaag
     6961 ttcttacacg agttattatt ggagtaaaat tgtcaactat atctatatag tatttactca
     7021 attcctctaa aatctcttcg cataaatccg tactatgacc aagattaata agaaactgtt
     7081 ttgtaaaatg ctttattaca gcttgagaag atatatcgta cttgtgtgaa gtataaactc
     7141 taattatttc aggtttcata gcaagtatac caatacaaga aagtattaat tcatcatgtt
     7201 ctatagattc tttatcatta acatatcttt tcatgaccat ttcggttaca cttctttgat
     7261 agcttaaaat agcttcttca taagctatat ccaaataaaa atttctatat gcttcgtttt
     7321 ttagaaggaa acaaaggtca gcattcatag caagaaagaa catcatcata gtaccttctt
     7381 catggtagtt atagattaaa gactgcattt catttcttat atcttcatat attatagctc
     7441 ctatttcgct tttacttgag aagtaatagc ttattagacc taaatttata ttagctcttt
     7501 ctgcaatttg cctagttgtt gtcttatgat aaccttgctc aaaaaataat tctctagcag
     7561 cacttataat actagctttt gtttctttgc ccttttctga ttttgacata tttactgtgt
     7621 atacctctct tttcaatctt tttttgaaaa tttgctaact ataaatattg taatagaacc
     7681 acctattata ggaaccaaaa ttctgtcaaa tacagtaaga ataccaatca tatttaataa
     7741 tgccaatata acacttacta taacagcata gatagctcct ttttttgtag cacctttcca
     7801 gcaaagacca attacaaatg gtgcaaatat tacacctgta cataatggag ctggccaaaa
     7861 caataattct aataaactat caaatttaag tgctatgatt gcacctatta tagctgtcaa
     7921 agctgatgca atttgagaat actttagagt attttttaaa tcattaaatt ctatattagg
     7981 atgtaataat ttgttataaa tatctcttga tataatagca ctcattgagg tcattaatga
     8041 atcggcagta gacattatgg cagccaatat agcagctaag aataatacag atattaaagg
     8101 tggcaaagta gtcgatatca tttgaggtaa aacctgaaca gatgatatat ttggaaataa
     8161 actaccacca atagctccaa ttattcctat agggaaagca agaaataata gtataaatcc
     8221 tgcaattaca ctacttttaa ctgcattttt agcattatca gcacattgat atcttaaaaa
     8281 actttcataa gaaaatattg agcctaaaac taatggtaaa actgtataca taaaatcact
     8341 aatcgattta tttcctggaa agaatggttc ttttaccatt gattgtaaca taagtaaagg
     8401 gttgtcgcca actaatttta agcttatata agctactatt ggcaaaaaca ctatacaaat
     8461 agcaagttga ataaatgctg atactgcaac tccccacatt cctgatgtat aagtatatat
     8521 aatgataact ataactccta taattacagc tatatcataa ggaataccaa atgcagtaga
     8581 tacagaacca aaagaaatca attgactacc cataatagct agtatagata ttggtgttac
     8641 aagactttga taagctctta aaaatacact atgaccatat ctagtttcaa tataatcagc
     8701 aggtgttata tcacaagata agcttcttaa ttttcctgcg aaaaatgcat ttataaagca
     8761 agctaaagct gcacctatag tagaatacat tccaacccaa agtcctcttt cagctcccca
     8821 ttgaactcca ccaactaagc accctcctcc aaaagatgta gcagcaatgg ttgcagctag
     8881 tataggcaaa ggcagatttc tacctgcgat taggaaatcg gatgctgttt taactttttt
     8941 tgaaaaataa aaaccaatcc atatgtatat tgcacacgta acaattaaaa gtaacatagt
     9001 cttttctcct ttataaaata ttttaataaa atatacaaaa tatatttaaa atatatttta
     9061 tataaaagta gtacgatatt tgttttattg gttttagatt aatatagcta taataattta
     9121 tgatattaga tggaaattac gtaaaaatag aaaattgaaa attctgaaat ttttgcatat
     9181 tgatatttat ctcatagatt cttttttgta attgtaacac gcttttattt ttaaatcaat
     9241 agtacatgta taaaaataaa aggaatttaa ataagaaaaa gatattttta atatctggat
     9301 gtagtataga aatatcttga ataaattatt cttgaataaa attataaaaa attaaaatca
     9361 ctagaaatat gataaaataa tttaaaatac gcatttcaat gacatttcaa aacaagaaaa
     9421 taataaaaaa caaacctaaa ttaagtctaa atagcttttt agttaatttt agtagtaaaa
     9481 aataaaactt aaaaagtgtt tgacaattat gaattttgag aatataatta aattaaaatt
     9541 atacacatat aaaaatatac tcctgaatca agaatgagat atttaagatt caaaatatat
     9601 attattatac gtgaataata aaaagtaagt aaattttata agggaggggt agatgtgagt
     9661 agtcaagaaa gcaaaccaaa aggaaatctt atatcaaatt ttagagatga tatgagagac
     9721 cctaagaaaa gagcaatata cacatattca agttctataa atttagcgta caattttata
     9781 ggttactttg tatcaactgt tacaaatatt tttttaactg atgtggcaaa acttggtgta
     9841 attatggcag gtggtatgca aattatacaa tctttcataa aaattgctgt agctcctata
     9901 acaggtacag tatttgacaa acaaccattc aaaaaaggaa agtattatcc atggcttaga
     9961 tatgcaccag cagcgttagc attaacatat ggaatatttt tcatagttcc attaatgaaa
    10021 ataagtccag cattactttt acctttgatg acagctttat tattaatagc atcttgtgct
    10081 cagcaagtag ttttcactat aatttatgct atttaccctg tagttgctaa gacacctaga
    10141 gaccgagtta taggctcaac tactacgaat atatttaaag aagttggtaa attcttagta
    10201 ggtttttcat atccgttatt attagtttta tttgcagatg tattaggtgg agaaggaatg
    10261 ggttatttag gtacctactt attctttgca gcaggatgcc ttttagtatt ttggttttct
    10321 tcaacagaga taataaaatc tggagcagaa gaagaagttc ttcaaaaaga agagaagcca
    10381 aagattaaag caagtgaaat ggcaaaagct ttattcacta atgtaccact tatgatggca
    10441 ttttgtttag aatttcttat atgtataaga tctataggat taggaccttt ggctccatat
    10501 tattttaaat atgtaataga agatgaacgt ggattagcag tatttttatc aatcatgcct
    10561 ttggtaagtg tagcattcat gtttttcgca ccagtgttta taaaaatctg tagagagcaa
    10621 aaactagctt caataatttc tttttctata tgtgcactat gccacttatt ggttgcatgg
    10681 actccttggg ggaaaactac tttaggagta actatgttgt tggcaattgg tggaggtttt
    10741 tcaaatgtag tatcaataat aaatcttaat ttctttgccg gttcttgtga ttatgggcat
    10801 tggaaatcag gaaaagactt acctggctta agtatgtcac tatatccagt tgcaatacaa
    10861 gtaggagtat tacttgcaac tactataaga acagttttaa tgaactcaat gggatatcaa
    10921 gctgatatgg tagtcacaga agcagttaaa tcaggtttta taaatatgat ttcttattct
    10981 atggcaatac ctttaataat agctgttgtt atagcaatac tatatccagt aagtgacaag
    11041 aaattaaacc aaataagaga agagttaaat caaagaaatg cttagttaaa agaaagttga
    11101 gtagatggtt aatttaagct attaaagtaa gtagacgcaa tagcgtttat ataaatgaaa
    11161 atacatatac agagggggct tttaaaaatg atagaaaaat tattgagaaa taccgtaaaa
    11221 gaattacatc aatatgttcc aggtgaacca atagaaaaag ttaaggaaaa atatggtgta
    11281 aaagaaataa taaaattagc ttcaaatgaa aatcctctag gaccatcacc aaaagcaata
    11341 gaagctatga ttgaaatgtt aaaacaaggt caactttatc cagagccaga agctaacgaa
    11401 cttagaagaa aattagctga aaagctagat ttaaaaccag aaaattttat tgttgctaat
    11461 ggtgcagata acgttatcac tctaataggt gaggctttta taaatagagg agatgaagtt
    11521 atatattgta acccaacatt tccatcatat agaactgcaa ctataaaaaa tgaagggata
    11581 ccagtagaag tacctttaac agaagattat aagtatgatt tacaaggtat attagataag
    11641 attacagata aaacaaaatt aatatgtgta tgtaacccta ataatccaac aggaacaatt
    11701 gtggatgata aagagttaga agaattttta aagaaagtcc ctgaaaatat tataactata
    11761 ttggatgaag catatataga atttttaaca gttcctaatt atgtggatgg acttaagtat
    11821 gtaagggaaa attataacgt tatagtaaca agaactttct ctaaaatata tggtcttgca
    11881 gggcttagag taggatatgg tattgctaaa gatgagataa taagaacttt atttacagta
    11941 aaagagcctt tctctgcaaa tcgtgttgct ataagtggag caacagcagc acttgatgat
    12001 gaagagttta taaaagaaac atatgaatta aatagagttg gaatggctta ctttaaagaa
    12061 gagtttacaa aaatgggatt tgatgttgta gattcacaat caaatttcct ttatgtagat
    12121 atgaaaacag atatacctaa gttatttgaa gacttgaaaa aaagagggtt tgtaataaga
    12181 ccaagtgcta cacatgcacg tgtaagtatt ggaactatgg aagaaaatag gaaatttgta
    12241 gcagttttaa aggaaatatt aaatattaaa ggagagccaa gtattggata atagatagaa
    12301 atattatgaa acggggtgta gatatgaact taaaaataaa cgcagagaga tgtaaaagtt
    12361 gtgaatactg cgttatatct tgtaaaaaag gagcattaaa aatatcaagt aagataaata
    12421 aagaaggtta tgctcatgta gaagttgatg agagtaaatg catactttgt ggaatttgct
    12481 atcaggtgtg tccagataat gtttttgaaa taattaaaga agaagcatgt caagaggctt
    12541 agaaggagtt gggataatat gaaaaagatg tggaagggga accacgccat tgcagaagca
    12601 gccctaagag gaggttgtga attttatgca ggatatccaa ttacaccaca aacagaggta
    12661 atggaatttt tatcacatag aatgtctgaa cttggaagaa cttttataca gtccgaaaat
    12721 gagatggctg ctatatatat ggtatatgga gcatatgcaa gtggaatgag gtctatgacg
    12781 agttcttcag gaccaggaat atctttaaaa caagaaggga tttcttactt atgtgcaaat
    12841 cattaccctt gtgtaatcgt aaatgtacag agatgggggc ctggtcttgg ctcattggac
    12901 tcagcacaga cagactatct aagagatact agagggggag gaaatggaga ttatcatttg
    12961 atagtttatg caccaaacag tattcaagag actgtagatt tgatgtataa ctcatttgat
    13021 gtagcggaga agtacagagt gcctgtcgaa attttgacag aagcagcttt aggtcaaatg
    13081 atggaaccag tagaatttcc agagtttaag aagagagaag gagatttagg ttggacttat
    13141 gatggaagta atagagacca tgcaaaggtt gcagataacc aaaagccaac tttttgtatg
    13201 gagaaacgta tgagaataac tgaaaatgaa caacaatggg aagattatca agtagaagat
    13261 gcagaatatg tgtttgtagc gtttggtata ccatcaagaa caactatgaa tgctgttaga
    13321 agacttagag aacaaggtga aaaagttgga ataataagac caataacagt atggcctttc
    13381 ccatataaag catttgaaaa ggtaagtaaa gatgtaaaag gatttatctc agtagaatca
    13441 acagacacag gtcaattagt agaagatgtt gctttagcct caaagaaagt atgtaaagaa
    13501 aatgtacctg tgtatggttt atttagtgga aatcatatac caaaaacatt gcaagtaatg
    13561 gacacttata gcaaaataaa atctggcgaa atcaaggagg tgttctaata tggctacaga
    13621 aaaattaaca cctagcgttg tttcaatacc aaacaagttt tgcccaggtt gtggtcatgg
    13681 aatagtaaat cgtataatag cagaggtaat agaagaacat ggatatgaaa aaaatcatgt
    13741 attaacatta ggagttggtt gtgtctgcaa tatgaatttt agctggaatg gtgataagat
    13801 gcaaactgca catggtagag cttcatctac agctatagga gttaaagtag cacttccaga
    13861 tacattagta atgacttacc aaggtgatgg agatgcttat gttataggtc tttctgaaac
    13921 tttaaataca gcatatagaa atcataatgt gactgtattt gtaataaaca ataataattt
    13981 tgcaatgact ggtggacaaa tgtcatggac cactatgccg ggtcaagtca caacaacaag
    14041 tgtaaatgga agagatataa agactactgg tagtccactg aaagttcctg agatggtggc
    14101 aaacttcttt gatgtagcat atgtagcaag aggttcagtt catagcccaa aggaaataat
    14161 taatctaaaa aaatatataa aaaatgcaat agaagctcaa ttaaatggag agggatattc
    14221 cttagttgaa atattagcac cttgcccaac taactggggt gtatcactag agaaatctat
    14281 caaatggatg gaagaagaaa tagtgccata ttatgctctt ggcgaattta agcaaaggga
    14341 tggtgaatag ttatggaaaa agagctagta tttgcagggt ttggtggtca aggagtttta
    14401 actcttggtc tgattgtagc tgagtcagca cttgaattgg ggaaacaagt aacttggatg
    14461 cctgcatatg gtccaactat gagaggtgga aaagcctata gtgtagtaaa gttttctgat
    14521 gagagtatag gtgggcctga tatggaagaa atagatgttt tagtagcaat gaataaacca
    14581 tctttagatt atataaattt agttaaagaa ggtggaacag tagttattaa tacatctgca
    14641 atagatgaga atgtaacatt aagagaagat ataagtgtag ttaaaataaa ttgtcaggaa
    14701 ttagctcaaa aagtaaacaa tccaaaagca gcaaatatag tagtacttgg agcattaatt
    14761 gctaaaactg ggttatttga aaaagaatta gctttaaaaa ctatgtgtga tttctttgag
    14821 gaaaaaggaa aaggaaagtt taatgttcaa aatgaagcag cattcatgga aggctataat
    14881 aacgccattt gataaattac ccttatctta agtgatttat ctcaagattt aataatcttt
    14941 agtgccaaga gaaacttcat cttgagataa aattcactta aaatcacaac tataaacata
    15001 taggagcgtg aatttatgag tttggaaaaa cttattagac caaaaagtat tgctatagta
    15061 ggagtgactg ataaacttgg ttttggaaga agtgcagcac ttagtatagt aaaaagtaag
    15121 gaaacagata gagtatatta tgttaatccc aaaagagaag aattgtttgg gagaaaatgt
    15181 tataagacga tacaagaagt tccagaagta gtagactgtg tagtagtatg tacgcctaga
    15241 aatgtagttc catctgtatt aaaagattct ggagagttag gaacaaaggc agcagtggta
    15301 tatgctagtg gatttgcaga ggaaggtaca gaggaaggta cagatttaga aaatcaactt
    15361 atagaaatat caaatacata cgatatgaaa atattgggtc caaactgcat ggggttgcta
    15421 aattgtatag ataaggttaa tctatgggca ggaggttcta aatgggattt agatactaaa
    15481 aaacctggta taggaattgt aggtcaaagt ggatttataa ctgctgaaat tgtttcaagt
    15541 gattatttta atatatctta tggtttttca acaggaaatg gaaatatagt tacactagaa
    15601 gatgcagtag atttccttgt agatgatgat tatgcatcag taatagcaat ttaccttgaa
    15661 ggtttaaaaa atcctcaaaa atttatagat gctttaaaaa gggcagcaca aaaaagaaag
    15721 ccagtaataa tattgaaatc aggaaggtca gaaaaaggtg ctatttctgc tgcttctcat
    15781 acaggaaatt tagctggttc gagtaaagct tttgaaagta tttttgaaaa atatggagta
    15841 atttctgtgg aaaatttaga acagtttatg tgtttagcac aagcttttag tgttttagat
    15901 ggtaatttac ctgcaaattc taattttgca gcaataaact tctcaggagg agaaaatact
    15961 atttgtgcag atttagcaga agaaaatggt gtagaacttg cagaaatatc ttctgaaact
    16021 aaagaagaaa tggaaaaata tcttccagga tttgcaacac ctaaaaatcc actagatgct
    16081 acaacagcat tattccatga aaaggatatg atagtaggtt tattacatac ctttgaaaag
    16141 gatgatagtg ttggatttac tatggtaggt gcaaatataa gagatgaaga aaatgaaatg
    16201 catgaaaccc tttgtaaagc tgtaagtgaa gctagagaac aaggattgaa aaaacctgtg
    16261 tttgcagttc ctacacttga aggaaataga tatttagatt ataggactag attagaagat
    16321 aatcaagtgc ctataatgtc atcagttgga actacattta cttgttttaa taaaatggct
    16381 aagtttatag attatgatta ttcaaaaaga actttagaat ttaaagctgt taagaaaaga
    16441 gagtcaaata atgtagtagc attatcagaa ttagatagta agattgagat gaaaaaatat
    16501 ggagtaccag ttccaggaca aggtaatgca aaaagtattg atgaattaga tgaaatctta
    16561 aaatatatta agtatcctgt tgttttaaaa ataaattctt ctgaaatatt gcacaaatct
    16621 gatgttggag gagttaaaat aggaattaag aatagagatg aggcagtaga tgcatataat
    16681 gagattttaa ctaatgtaaa aaaagcaaaa ccagatgcta atattgatgg tatattagtt
    16741 caagaaatgg tagaaagtgg tatagaaatt attattggta taactaatga tgaccaattt
    16801 ggaccaatgt tattagtcgg tttaggagga gtatttgtag aggtatttaa agatactaca
    16861 ttatatccat tacctataaa tcatgatgaa gctattatga tgcttaaaaa actaaaatca
    16921 tttaagcttt taaatggcta tagaggaagt gagccatgtg atattgatgc tcttgcagat
    16981 atgatggtca agttaggaaa atatgcttat gaaaataagg atgaagtcaa ggaaatagac
    17041 ttaaatccag tgtttgtata tcctaaagga aaaggcgtat gtgcagtaga tgccttaata
    17101 gttaaatata aatagtttat aagttttggt attcaaccat aattaaagca ccaactgaaa
    17161 atcacatttt gtaagttaga tagtgtgatt ttcagtcacc ccaaatttaa tttaaaaata
    17221 ttttaaaatg aaagtatagt tttaagtttc attgtgaaat agcactgtat aaacaataaa
    17281 atactacgta taaaacgaat aataaaaggt gttttaatga taagaatcaa tcttgatttt
    17341 cattaaaaca ccttctttat tatattaaaa atttttaaac gttatattgt cacaggtggg
    17401 tttgttggag ctgcatatgt acgattagca aattcttggt caacaaagaa tagcccaccc
    17461 tctccagcaa gtttaacacg ttttatattg tcttcacaat ttgtttcttc ttctgcttgt
    17521 tcagatataa accaaagtaa gaattgagaa gttctaaagt ctgattcaga gtttgctaca
    17581 gctgctaagt tgtttattaa agctgtaacc tttttttcat gagctaacgt acgctcaaga
    17641 atatccattg cagaagtaaa gtctgaatct ggcattggga tagcatcaag ctgaaccttt
    17701 cctcctacat tatgtaagta tttgtaaaaa aacatagcgt ggtctgtctc ttctttatat
    17761 tgaacataaa accaattaga aaatccttta agtccttctg cttcaaggta agaagacata
    17821 gaaagataaa gatacgcaga atataattca tggttaatct gctcattaag taatttttcc
    17881 attttagctg aaatcatttt tatacctcca aattttaaat gctcttataa aatataataa
    17941 tattaaatgg aaaaatattc aataaaagtg tttaaatatt ttacatattt aataaaaatt
    18001 tatactacca ttaaaaaaat tataacttac aatggctata gagccaatta atggtgcatt
    18061 tgctccaaaa tttgaatgcc ttacacttat ttttttatat ttagaaaaac ttgctgaagc
    18121 agtcaatttt tttaataatg tattttctat aaatgtacca ggtatattaa agtcatagcc
    18181 tattattata gaactacaat caatcaatgt aagtgtatta actaatgcat atgatacgta
    18241 tgtacaaaat tcatcaagca aaaacatggc aagactatct ttattatttg cctcatctat
    18301 taacttgact aaagaaaaat ctttacagtt aattaatggg gagttaggat aaatatggct
    18361 caatgattca attcttttaa ttagattact gacacttgta taataatcta aacatccatt
    18421 gttaccacaa ctgcacaatg gtccactaaa attaattgat gtatgtccta tttctccact
    18481 ttgtcctagg ttgccagtat gaagtttatt ttctagaact agaccagctc caataccatt
    18541 cattatgtgt aggtatatat aatttgatat atttttacct aaaccataca ttttttctgc
    18601 taatgcaccc gaattagcat catttatcaa aaatattggc aaatcagaca tttcttttat
    18661 aaaatctact atatttaggt ttgatacatt tccaaaatct gggggattta gtatggtacc
    18721 atttatatca tctactggac ctattgaaga aataccaatt ccaattatat ctctcttgtt
    18781 gattttcatt attttagtaa acattctttt tattatatct tttaaaacat catttgatag
    18841 aaatttaggg taagtttcag aaagttgttt tacaatatta ccttttaaat ctgaaataat
    18901 taccttacat atatttcttc ttattaggat tccacaaata caaggcgata tattagaaat
    18961 atctaataaa ataggtttac gacctgatga atgtgcattt aaagttgatg actctatttc
    19021 cctaatcata ttttcattaa taagttcagt aactagattt gataaagtca ttttagtaag
    19081 tcctgtagac ttagctaaat caactctgga cataggtgta tttgtagaaa gtaatttcaa
    19141 tattattaac ttatttttaa tttttacatc tttgatgtta gaaccttgtt tgttactcat
    19201 cataaatctc cttaaataaa gttaagtgtt ttatttattt tcaagtatac tatcacctta
    19261 taatagagta acattttttt acttgaaaat atcattaatt agaatatatc acattatata
    19321 tcataaaaca tataaaaaaa tattagaatt aaattaaaag tgaaaagtag attgatatat
    19381 aaatagtaaa tacttaatta aaaaaagata atgatagcaa taattattgt taccaagaat
    19441 ctactacttc aagtgttacc ttaggtattt aagttgatag tggtttgcac gtaataaact
    19501 tgatgtaata tatattctta ataatatcga taaaagattt acttaaaaat aatatagatt
    19561 atgtaaacat ataatctatt tattgtatac aataaaattt cattttgtaa aacagtgaat
    19621 taaatatgta atatagatat cgatttttat tacaaattgt tactaaatat aggtacatta
    19681 gaacaaaaat ctagtaaatt gtaactaaaa tgtaaatttt tcctttaatc tatacaatat
    19741 tatggaaact ttttgtaatt tatgatataa taacaaatat ataattatta aattataata
    19801 aatgactata gcgtagatgt aatactatgt tatagtcatt tttgaattaa acttgatata
    19861 tcaaggggga agaatatgag aacaattaga agagttttag cattaggttt aacattagct
    19921 atatttctaa taaatgtacc taatgtagat gcattaacat cagatacaat taaaggtaac
    19981 aatatatatg agacggctgg attaatagca gataaaaaga gttatgatac agcaattatg
    20041 gtaaatatgg ataattctat agcagatggt ctttcagcaa gtggtcttgc aggtgctgtt
    20101 gatgctccaa ttttgcttgc acaaaaaaat aagataccaa atgaaacaaa acaaagatta
    20161 aaaaatgtta aaaagatata cataataggt aaagaattat caataagtaa gtcagtagaa
    20221 actgaactaa aaaacacagg ggcacaggta actagattgg gtggagatga cagaataaag
    20281 actagttata gtgttgctaa agaggtaaat ggtatcaaaa aagttgatga agtgatatta
    20341 actaatgcat ataaaggaga agcagataca ataagtgctg cacccgtatc agtaagagat
    20401 atagctccta tagtacttac agatggaaag agtgtgcctt tttcaacaag caatgtaaaa
    20461 acatatgcag taggtgggag tatatcaatg agcactagtt tagttaataa aactaatgct
    20521 aaaagacttg gtggttcaga tagatatgat acaaataaga aagttataaa agagttttat
    20581 ccagatgcat cagaatttta tttgagtgat ggatatgatt tagtaaatgc acttacaggt
    20641 tctacaattg ctaaggaaaa tccaattgta ttggtgtcag aaagtagtga taagtctata
    20701 ttagcaggag cagataagat tactagatta ggttcaataa gtgacagtgt gtataataag
    20761 tgtgtttctg ctgcacaaaa taatggcgat tcgtctacaa aaggtgagtc acctatgaaa
    20821 aatgagacaa gcatattagg tcagccaaca gctagtttag aagcgtgctt aaaatgggca
    20881 aaatctaaaa aagctaatga tttatttata gagttaatac caatattata tgatactgct
    20941 gttcaggaag gtgttaatcc tgttttggca gtagctcaat ctgcaaaaga aactggtttt
    21001 tgtaattttg gtggagtatt agatgcatca tttaagaatc cttgtggact taaaacttct
    21061 gtaggtggtt ctgatactga taagaatgcc cattcaagat ttgatacttg ggaagaagga
    21121 atattagctc aaattcaaca tttatgctta tatgcaggac aagatggtta cccactttca
    21181 aatccagtag accctagaca tgaaaaatct ttatttggta aggctaaaac agttgaaagt
    21241 ttatctaata attgggctgg aggtcaatat ggacaagatt tagtaagaat gatgggagaa
    21301 attgaggcaa caaaataatt gaagattatc aaatatccaa taaataagga ttgattatta
    21361 tgaaaaagag taatattttt agtatcatat ttcctacagt cataatggtg ctaatgtttt
    21421 taacttttgc tacagatata tttaatattc cagatattca atctaaaagt atttttgttg
    21481 tgggaatggt tttgattttt ccaatttctt ttttgataca agggataatt tgtgtattaa
    21541 ataagactaa ttggatttta tctcttattg tttctttagt aacttatata gtattaatgt
    21601 atatattttt aaatgattct gcatatatat atgttttact ttatacagct ttttatatga
    21661 ttggacatat aacagctaaa ctctattaca aaattaagac ttttaaaaat taaattgaag
    21721 tatataaaag taacattagg agaagtatcc ttaatgattt tctaaaatca gaaataggtg
    21781 cttctctttt ttgtaaaaat aaaagtatgt aaataaaatt taaccattat aattttcttt
    21841 taacaaatgt atacaataaa cttgttgtat aattaagata gataaaataa agggagggat
    21901 aatatgaatt taatagataa tcatattcat actaattttt caagtgatgg aaaggattcc
    21961 atggaagata caataaaaaa agctataagt attggtgtta gatatttgac ttttacagac
    22021 catttagaac atgatgaaga tagaggattt tgcataaatt ataatgacta tgttccagta
    22081 tttaataagt ttaaagaaaa atataaaaag gacatagagt tattactagg tgttgaagtg
    22141 ggttacagaa aacatctaaa aaatgaaata gaagaaataa taaattctaa tccttttgat
    22201 tttgtattgt gctcaactca tacaattgac aatgtacctg ttccatcaaa ggcgtatttt
    22261 aaaggtctta gcaaagaaga tgcgtattat aaatatttta atagcatact tgaaactaat
    22321 cgtgaatttg gagattacaa tatatatggt catttggatt atatatctag gtatggaata
    22381 tattcagata atagagttat atacaatgac tttaaagatg ttattgatga ggtcttaaag
    22441 tcaataatca ataatgggag tggtatagag ctaaatactt ctggttatag atatggacta
    22501 aatgctatac atccaaatga agatattcta aaaagatata aagaacttgg aggatttata
    22561 gttactgtag gttctgattc tcatagggta gaagatatat gcaaagattt tgatgtggcc
    22621 tatgatatgc ttaagtatct tgactttaaa tatgtatctt tatttaaaga aagagaaacc
    22681 tattttgtaa atatagaaaa agttaaatct aacaatatag cttagagtgt gttttgaagt
    22741 aaattaatag atagttaaaa agttaatagt tatagtattg tatcctctag aaaaatacta
    22801 gaggttttta ttttgctaaa ataactaaat agaattaaat ttaaatagta tagcttattt
    22861 taaattgaat agtttattgt tgatatattt tactattata tatttttatt gtgatataat
    22921 agtaaaatat attaacc
//
LOCUS       DAMJWC010000056        22776 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMJWC010000056 DAMJWC010000000
VERSION     DAMJWC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.056"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            223..1659
                     /locus_tag="PC503_002678"
     CDS             223..1659
                     /locus_tag="PC503_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2528644.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            complement(1751..3625)
                     /gene="asnB"
                     /locus_tag="PC503_002679"
     CDS             complement(1751..3625)
                     /gene="asnB"
                     /locus_tag="PC503_002679"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2528645.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            3828..4502
                     /locus_tag="PC503_002680"
     CDS             3828..4502
                     /locus_tag="PC503_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2528646.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            4615..5151
                     /locus_tag="PC503_002681"
     CDS             4615..5151
                     /locus_tag="PC503_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2528647.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(5317..5937)
                     /locus_tag="PC503_002682"
     CDS             complement(5317..5937)
                     /locus_tag="PC503_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2528648.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(6251..8389)
                     /gene="vanT"
                     /locus_tag="PC503_002683"
     CDS             complement(6251..8389)
                     /gene="vanT"
                     /locus_tag="PC503_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2528649.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(8407..9213)
                     /locus_tag="PC503_002684"
     CDS             complement(8407..9213)
                     /locus_tag="PC503_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2528650.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(9210..10310)
                     /gene="vanG"
                     /locus_tag="PC503_002685"
     CDS             complement(9210..10310)
                     /gene="vanG"
                     /locus_tag="PC503_002685"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2528651.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(10571..11653)
                     /locus_tag="PC503_002686"
     CDS             complement(10571..11653)
                     /locus_tag="PC503_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2528652.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            complement(11703..12404)
                     /locus_tag="PC503_002687"
     CDS             complement(11703..12404)
                     /locus_tag="PC503_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2528653.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(12838..15369)
                     /locus_tag="PC503_002688"
     CDS             complement(12838..15369)
                     /locus_tag="PC503_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2528654.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(15477..16094)
                     /locus_tag="PC503_002689"
     CDS             complement(15477..16094)
                     /locus_tag="PC503_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2528655.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(16456..17340)
                     /locus_tag="PC503_002690"
     CDS             complement(16456..17340)
                     /locus_tag="PC503_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2528656.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(17531..18781)
                     /locus_tag="PC503_002691"
     CDS             complement(17531..18781)
                     /locus_tag="PC503_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528657.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(19003..19767)
                     /locus_tag="PC503_002692"
     CDS             complement(19003..19767)
                     /locus_tag="PC503_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528658.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(19761..20486)
                     /locus_tag="PC503_002693"
     CDS             complement(19761..20486)
                     /locus_tag="PC503_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528659.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(20488..20856)
                     /locus_tag="PC503_002694"
     CDS             complement(20488..20856)
                     /locus_tag="PC503_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2528660.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(21032..22576)
                     /locus_tag="PC503_002695"
     CDS             complement(21032..22576)
                     /locus_tag="PC503_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2528661.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         7854 a         3834 c         2379 g         8709 t
ORIGIN      
        1 tagcggtatt agattacaag cattattcta acttttttta tattaagacc ttacctttca
       61 tccctacacc taaaggagag ggcttttcgg caattttatt gtaattatat atcatttata
      121 taaacaagta catattttat tttgaaacta caaaattatt gtactatatt gttttaagtt
      181 gttttataat agattatatc atcttattat aggagaaaaa atatgatttg tactattaaa
      241 ccattaaaga tttcaataaa aaagtctact gaacctctaa ttgaatttat atctgatact
      301 acctataaaa ataagagttc ttcatatatt aaagaagtct actttacaag atatataggt
      361 gttgatgatt caattgataa atacatagaa aaaattaaaa atatagatac ttattttttt
      421 aataatccta caattcccta tattagatta aacaatctaa aaataaattt tgacaaagaa
      481 caaacagata agatgcttaa aatttttaat atttataata gttctaagtt taacagttgg
      541 gatttatata atatcgactt tccatgtaaa atagaaaatg acaccttaaa ttggactaaa
      601 aagattgcat ttaaaaatac tttagattta ttttccacaa gtatgccaaa ttgtacatcc
      661 tctatcatca aaaactttgc agttaaactt ttgtgttgga tagactattt tctacctaaa
      721 ttattttata acaaggtgaa gactactatt tcaccaaaga tagtatactt tggaaatatt
      781 aaaaggcaag aacttttttt cttatatttt ttatcacaac ttgggtgtga tattttatat
      841 ataaatccaa ataaagatat tcttgattta tatcctgaat gttcaaaatt ttctactcta
      901 tttgaacttt ctaggaagac tccaaatata ttagaaatac cttttgaaag gcatattaca
      961 aatataaatt acagtgaaaa taccaataag acttctccta ctacgaataa acctaactct
     1021 aaaaatacac ttaataacac aaatctaaca tctaaaaaaa ttgtacaaga tgaggaagta
     1081 gaactttctt atgaagacct tgcaaagtta tcagcttctg ttgttatgat tgttgtgtgc
     1141 aataacgaaa ataaaccgtt taagagcggt tctggagtag taataaataa tgaaggttat
     1201 atacttacga atcttcatgt agtcaatgat gggtattcat ttttagttag atttgaaaat
     1261 gatgataaag tttatacatc ttaccaaatt ataaaatacc attcagatta tgatttagct
     1321 gtgataaagg ttgatagaaa atgcaagcca atacctgtta aagtcagtaa aaaacctgtg
     1381 agaggtcaaa aaatagttgc aattggaagc cctctaggtc tttttaatac agtttcagat
     1441 ggaattattt cagcttttcg tgattttgaa acggttcaaa tgatacaatt tacagctcca
     1501 atctctagtg gtagttcagg aggagctctt ttagatatgt ttggaaactt actaggattg
     1561 atttccgctg gatatgatga tggacaaaac ttaaatttag ctgttgaaag tagtcttgtc
     1621 aaaatatttg ccaataattt tattgagata gtaaactaat caatcaaaat tctacttatc
     1681 ctattccata ataatcaaga gggtgaaaac attgcatgct tttgccctct gattaatatt
     1741 gaaaaaagta ttaatactcg acatttttat gctcaataaa taattgatgc catagacaaa
     1801 atgtaaatat agtccatatt tttctcgaat tatctctatg acctttaaga tgcgtatcta
     1861 aaagttttat tgcatatttt ttatctataa attcatctac atttgaatta taaatagttt
     1921 cctttacaat atcccctaga gaatctttta accaaactct tattggagtt ggaaatccta
     1981 attttttcct ttgaacaaca tgttctggga ctatttctct aaacgcctct ctaagtaaaa
     2041 cttttgtatt attcttattt attttttgct ccattcttaa attttttgcg acatcaaata
     2101 catctttata taaaaatggt actctaagtt caacctgctc agctgtagaa agtttgctaa
     2161 ttttttgaag tatatcgcct tgaagccatg tattcacatc tatatgttgc attttactta
     2221 tataatcgta attatttttt tgtgcatctc tatacaaatt agacaacagg tattcatata
     2281 tattcttttc cttatactta aaaaagaatc tttttacttc gctgttttca aaaacttttg
     2341 catttcctat atatcttttt tctaatggtg ttgtagctct ataaagataa tttcttcctt
     2401 ttatgtttgg cataagttct gaaactcttc ctaatatact tttaatataa gtaggtgaat
     2461 tgacaactga tttcatagta ctatactctt tatatatatt atatcctcca aataattcat
     2521 ctgctccttc tccagacaat gctactttaa catgtttacc tgcctcttta attaagaaat
     2581 aaagacctac ttctgaaggg tctgctatag ggtcatccaa agaataaatt acattcggta
     2641 atgattttat atattcatct tgtgttatat taatctggat attttctata cctaacttat
     2701 cagctgtttt ctttgctact tctaattcac tatatccttt gacactaaag cctgcagaaa
     2761 aagattttat atttggatta atttgtgaag ccacagtagt tataatagat gaatctattc
     2821 caccagacaa aaatgttcca atttctttct cctcttccat atgagttact attgaatcta
     2881 ctactatatt tcttatatca tcctcattca catctctatt gcctaagtga tttttagtat
     2941 aaaaaaattt tgtactactt ctaaactcaa gtttattata tctctttaaa gatagtatac
     3001 cattttctac cctaaaatag tgacctgctg gtatcagcct tattccttgt atcatagtat
     3061 cttcaggaag tacatattga aatgaaaaat aactttgtaa gcttctttca tttatattta
     3121 aatttttcat atattcaagt aaaaacttat actctgagga aaaaattatt gcattttcct
     3181 tatttatata ataaagtggt tttatcccaa ataaatctct tgctccaaat atactttcat
     3241 tttctctatc atagattata aagttgaaca ttcctttaat cttatgtaca caattcttac
     3301 caaattctat ataagatgct aataagactt caatatcatc atttgtagta aaattgtgtc
     3361 cttttttaat taattcttct tttatttcat gatagttata tatatttcca ttaaaaacaa
     3421 taacttttcc atctttttca aatggtttat ttccataaat agcatcaatt acattaaatc
     3481 tttcaaaatc aaaagttttt tcctcatcct tatactctat tctactagaa agtcttgtat
     3541 tatttacaga ttcttttatt ttaaatttaa tatcttcttt tttagatata tcacctttat
     3601 aataaattga aatattgccg tccatataat caaaattcct ttctgtcctt tagtcttatt
     3661 ctatatttca tagttttgtc tttggcttta aaacttattc aatttaaaat gaaattgcta
     3721 ttaaattctt ataaattatc tgttaatatt tcatattttt tttatttcta gaaatactat
     3781 attaggaggt gatttttatg aagaaaaaaa tattaatacc agttattatg tctttattta
     3841 taatctcaca gtgcataact tcatttgctt ttacacctga aaataacaaa tttaaggtta
     3901 aaccattacc ttatgcatat gatgcacttg aaccttatat agataaagaa acaatgaaac
     3961 tgcatcatga taagcattat caagcttatg ttgataaatt aaatgctgct cttgaaaaat
     4021 atcctgagct ttataattat tctttatgtg aattattgca aaatttagat tctttaccta
     4081 aagatattgc tacaactgta agaaataatg caggtggagc ttataatcat aaattctttt
     4141 ttgatataat gacgccagaa aaaaccatac cttctgaatc tttaaaagaa gctattgata
     4201 gagactttgg ttcttttgaa aaatttaagc aagagttcca aaaatctgct ttagatgtct
     4261 ttggttctgg ttgggcttgg cttgtagcta ctaaagatgg caaattatct attatgacta
     4321 ctccaaatca ggatagccct gtaagtaaaa acctaactcc tataatagga cttgatgttt
     4381 gggagcatgc ttactattta aaatatcaaa atagaagaaa tgaatacatt gacaactggt
     4441 ttaatgtagt aaattggaat ggtgctttag aaaattacaa aaatttaaaa tctcaagatt
     4501 aattaaatat taaaatcctt ttgaaaaaaa cttatgtttg ctatataata taataaaaga
     4561 tagtctaaat ttaccaatat aatgtttata gtgacgattc aggaggattt ttatatgata
     4621 aaagaaacac atgaaagggg aggttatata ttcgcacttt tgatactccc ctttataaac
     4681 aatctatacc tagttaaata cgatattgca tataaaatag tattaattat aatttatatt
     4741 tattttgcat atttaggttc tttatttcca gatatagata tgagaggttc ttacataagt
     4801 aaaaaattta tgttaatata caaattattt ggaagtaggt ttagacatag agggtttact
     4861 cacagtctaa ttgccttatt acttatttat agttttttta aatctctgac aatcttcact
     4921 aacaataata tagttttctc atgtttgtcc agtgggttta taataggata tctatctcac
     4981 ttgtgtcttg accttattac taaagaaggt attgaattgt tttatcccat taccataaac
     5041 atttctttac tacctataaa aactaactca aaaacagaaa aattcatatc taagctatta
     5101 aatttcatag ttattttttt gattggatat caattttata ttttattata gttgtagaaa
     5161 aaataaataa caatattttg aactaagtat aaataagttt tatatatttt agtttacaaa
     5221 agaactaaaa attttgtacc ttaatacaaa aaataaaacg tatcttaaaa taatttagta
     5281 ctaaatcatt ttaagatacg ttttatttcg tacaagctaa atcattttat catctttatc
     5341 attgtgatgt tttttatgat ggaaatcata attatgattt tcaagatttt tatttactct
     5401 atttccaatc ttccatgaca aaaacaccaa taatataaat gatgctatct ttaaaggact
     5461 tgttataaaa ccttctatat cacttgccac gtaacttata actataaaca ttacaaattt
     5521 tcctgccaac attgctggca caaaatcttt taaatctttt ttaccaaaag ctgatgcgat
     5581 agtaactaaa caaccgggca taaatggaca ggcatacgct ataaataata acttaaatcc
     5641 ctgtttatcc atccaactta ttgctttttc agttttacta tttctcaact tattaaaaag
     5701 cttactatca ttaaatctgc ttattaataa gaataatgaa gttgtcccaa gtcctgagcc
     5761 aatccatgat aacaaacatc caataaataa tccttgtatt gcagcatttg ctgtaactat
     5821 agcaacaagt ggtaaggctg gtataaagct ttctataaat gcacttaata agccgattat
     5881 tgtggctaac acccaataat tttgagtcaa atcaagtagt tcttgtatat actgcatatt
     5941 gcttttcccc ttttttaact ttaactatta ttatatactc tatatgttta ttatatacca
     6001 atctcaaaaa atgaatctaa tattaaaaag taaataatct atataagttt acagttaagg
     6061 tataattatt ttattatata ttataacaaa aaaggtgatg tttcaaaata aaaatctgaa
     6121 acatcacctt tttataactt aaattgtcat gtaagttata aaaaatatat attagacata
     6181 atattactaa aaatgtctag tcagagtaaa ataaattaca cagtacaaca aatattacta
     6241 tttaattgag ttacttcttt ataacattta accttcttcc tactctgctc aataattcat
     6301 tcgatatact acatgagtta tttgcaactt cagaagcaga taattcagat aaattatctc
     6361 ttcctattat tattgccgta ttaccaactt ctacattagg tatatctgta atatcaacag
     6421 caagttggtc catgcaaatt cgacccacta ttgctgctct acaaccattt attattacgt
     6481 aactttttcc acaggataaa tttctaggta taccatcggc atagccaata gataatatag
     6541 caattacgct atctctgctt gcaataaaga ctcttccata tccaaaacta tcatcttttt
     6601 gtatttttct aataagaatt acttgtgatt ttaaggataa aacaggtcgt aaatcaagtt
     6661 gcaatttagt cgtatcattt ggagaactta atatcccgta taatgcaatt ccaattctta
     6721 cataattaca cttaagattg ggataattaa aaaaaccata actactttga atatgtactt
     6781 taggaatttt tatacctttt tttaacagaa aatcaattaa cttataaaaa cattcaattt
     6841 gtttatttgt aaagtctaca tcttcatctt tcagactatc tgaaacacac aagtgtgtaa
     6901 atatgccaca tatatctaag tattttaatt taaatgcctt taaaattgac ctcacatcat
     6961 taacatcaaa acccagtctg tgcatacctg tatcaatttt aatgtgtgat tttatgttgt
     7021 atttctgttt gtttaaagag atagcatgat taaggtcaat aacactctgt gtaagattgt
     7081 atttatgaag ttcctttgcc cttattgggt tagtatatcc aagaatcaat atttctccta
     7141 gtattccata tcgacgtaaa tcaatcccct catctattgt tgctactgca aatgctttta
     7201 cacctatttg gtttgcacaa gtcgctactt caaaagcact atgaccatag gcattagctt
     7261 ttacaactgc catcaattca caatcttctg gcatagcttt ttgtatcatc tttacattat
     7321 gttccaaatt atttaaatca atttcaatcc aagctctatt ggtatttacc ttatgttctc
     7381 ctttcaagtc tttttttaga ggtttaagaa tcaatataat aattatagaa gctataaaag
     7441 atgctatact taccactata taatgaataa ggctattgtc aaccaagaca gtttgtattc
     7501 cgaatatttt agaaaacata cgaataacaa caatcatcat aggatgtata atataaataa
     7561 ttaatgatga tgttcgcaat aacctagctc gagaaccttt caaaaatgtt aaggctgtaa
     7621 ataagaaata catacatggc aataacataa tatacatgct atcatgacgc tgtaccccta
     7681 gtttatgtaa aaacattccc tcacataaca taagtaagaa tgatataaga aatccaatca
     7741 agctattttt agttgacata taattagatt tattagatat tattccacca agtatgaaaa
     7801 atacaggtgc aaaaaatata ccatttcgtg tataatctga tacttcaaaa atatacccat
     7861 ataaattctt taatagtggt attttttcta aaaaaccata ataactatca ccaaacatac
     7921 caattacata aataacaata gtgattacta gtgagtactt taaacctagt ctttttacaa
     7981 gaaagtatgc aatacttgca ccaataattg atgcaggtag ataccataaa tgatataaag
     8041 tcccatcaaa tacaatgtcc ttaataatat tgggcactaa attattcatg gaaaaatatc
     8101 cagtgtaaat atttaaggga atataaatta caatagctat cccgtaaata aataatacat
     8161 tttttagaaa agatttcagt ttattacaat tataattata tgttgaaatt agaaaaaagc
     8221 ctgatagcat aaaaaagaat ggcacagcaa tacgagcaat tatactagtt aacacaaagt
     8281 cagccatttt actatatgat aataatggag atgtatgaat tgcaattata agtaatgcag
     8341 ctataatcct aaaataatca agccctgcat aagatttatt cctaatcatt cttgttcctc
     8401 catttcttag tcctttctat ttctccaaaa tgtcacaata aaaccatcct tattgttacc
     8461 cgatatttga tatacacatt gttcaggtat agagattctc acttcttctt tagtatgaat
     8521 aggcacataa aagatttcta taattttttc tttatcttct atttttaaac aatttgtata
     8581 cgaaaatctc ttaatatatt ctatatattc ttcaagagcg agattcattt tattgataat
     8641 ctcagaatgc ggatatccca cataacgaaa atgccatggt tcttgagata ttcctgttat
     8701 ttcttctttt ttacactgat aacgctctat aaaaccataa tgtagtgctg ccttacgaaa
     8761 ctcattacaa ataccattat aaggaaattc agggcagata aaatctataa cttctttctt
     8821 taaccctaaa tcaatagcaa gccctgtctg atgttcactg tgatttggaa gtgctacaaa
     8881 ctttttagta aagtcttttc cattgtcacg cagagaactt gaatatatat cttgttgttc
     8941 ctctgcagta cgatatccac ttacaggtac tatttcattt attccacata tactttttaa
     9001 aatattttgt aaaatgtttg tagcttcacg tttcataaga atacttggaa accttgtatc
     9061 tacaggaatt aaatctatat cttcagatgt tttaactggt aaaaaagcat ttactagaat
     9121 tagattccca tcataaactt tatctttagt caataagata gtatttgtca ttttatcttc
     9181 tttattttta tctaataaaa tattattcat cattttatgt acacctcaat tatcttgtcc
     9241 aatatttctt caaaagacaa tccaatacct ttcatcatat ttggataacg actatgagaa
     9301 gtaaagccag gaattgtatt gacttcatta aaaataattt caccagatgg agttaaaaac
     9361 atatctactc tagcaaatcc agaacatcca agagttctat aaataatttt tgctgtctct
     9421 tgtattcttt tctcacaatc caaatcaatt ctagctggca tatgaatttt tgaacttttc
     9481 aatgtatatt tttctgtata atcaaaaaat ccttttgaca attctatttc atctactctt
     9541 ccaacaagta agtcatcgtt tcctaaaact gcacacccta cctcaaaacc atcaatattt
     9601 tcctcaatta ttacttcatt atcatgttca aaagccaagt ctactgctac ttgtaactct
     9661 tcttttttat aaattttact aataccaaat gatgaacctg cacgcacagg ttttataaat
     9721 aatggataag ttaagtcttt tgacagttca gccacattaa atttatctga gtattttagt
     9781 aatattgatt ttggtacttt aataccttct gaatgaacaa gtttatgtga tttgtctttg
     9841 tccatacata atgctgaaga aagagtacca catcctataa cctgtatacc tgccaattca
     9901 aataacccct gcactgttcc atcttctcca ttttttccat gcagtacagg aaacacaaaa
     9961 tcaagtttag tgtatttaat atcattttca catgattcaa tagcactatt tggaatatga
    10021 ttctgagaaa cagcatcagg aattaaaaat tcaataatac catttttgac acggttctgc
    10081 gaaacaataa ctggaattat atcagtatcc ctttcaaacc aagtgttatt ctggatatta
    10141 ttataatctc caatataatg ataccaatta ccctcccttg taattccaat tggtataata
    10201 tcatattttt ccgtattcaa attctcaagt actgcaaaag ctgattgtaa tgatacatca
    10261 tattctgttg agtttccacc aaatataact gcaatttttt tattattcat ctttgattct
    10321 cctttgttga tttatttatt tttatacaat ctacagaaac atgttaaaat actttttcta
    10381 tttcaaatcc aatcaacctt cacttacaat tgcatctgtt ccacataata tattttcaca
    10441 tttttctatt gatataatta ctgtatcaaa ataaaagcac tcttgttttg atacagtaat
    10501 tatatcaata acaagagtgc tctttattta tttatcctaa agaatttcct atttttttat
    10561 acttaaattc ttacaaattt cctacaatcg gaataataac cttaaagata attatattgt
    10621 tctcgctatg agctgttatt gtcccgttat gaagctccac tatttcttta gctatagcaa
    10681 gtcccaaccc agctctacca ctgtttgaat tacgagatgt atccaacctg taaaattgtt
    10741 caaaaatacg ctcaagtttt tcctctggaa tcgtattgct atgatttata aatttaagct
    10801 ttatataatc atcctcctgt acagctgtta tttcaatagt agtatcttca aaactataat
    10861 aaacagcatt tcgtaataag ttatcaaata cacgttgcat tttattaaca tcacacctta
    10921 tcatcatatt tggtgtaaca ttcagtgtat attttaaatt cttactcatc aaagtaggtt
    10981 taaactcata tgttagttgt tcaagcatac gagttaagct tactgtactg tattcaagtg
    11041 atatatttga taaattaaac cttgtaattt caaagaattc attaattaaa tcttcaagac
    11101 gctctgcctt atccaacgaa atagataaat atttttttcg cagttcttca gaaatctgac
    11161 tttcatctcg aagtagtgtc agatacccta taactgatgt aagtggtgtt tttaaatcat
    11221 gtgcaagata aacaataagt tcattcttac gttgttctgc catttgtgtc tcaaatttac
    11281 gttgttcaag tatatgttta attgagttta ttttcttttc tattgccaat aactctggag
    11341 ataaagccac ttctccaaca tcttctttga taagagagtc aataccttga tttatttcac
    11401 taaaatattt tgtaaaccaa tttaaataaa cccggaatat tataaaaaac acaatcacca
    11461 tagctagtat catgaagagc tccatgctat tacggaaaat ctgctgatat aaattcaatg
    11521 cagctttata ttccatacga aaagcatttt caaagaatga tactatccag atagaaaact
    11581 taccatacaa tataaaagaa tataaaatcc atatgaaaat aatggctata aatgccatta
    11641 aagctgttct cataaaaatt ttatttctca cttgagtaaa gtcaggattg actttaatat
    11701 ttttactttt caattgtata acctactccc catacagttt ttataaattt cgggttttta
    11761 gaaggttcat gaattttttc acgtaatcgc cctatatgag ccataactgt gttattatta
    11821 tcaagatatt tttctcccca tacagcttca aacaattctt cagaaggaac cacttttcct
    11881 tgatgttcac ataaatacca aagaatagaa aattcaatcg gtgttaatgc tacttctttc
    11941 ccaaataaac tacatttatg tgtttcttta ttgataatca atcctttaat atcatactca
    12001 ttaacaatta tcgactgttg ttcataagaa ttattatatc gcatatatct tcttaattgt
    12061 gtctttactc ttgcaacaac ttccaaaggg ttaaatggct ttgttatata atcatcagca
    12121 cctatggtta aacccattat cttgtctata tcttcaattt tagctgttaa cataatgata
    12181 ggataatagt atttttctcg aattttctgg caaatatgaa atccatcaat atcaggaagc
    12241 ataatatcta aaatagccat atccaaattt ttagattcaa tacattctag agcttcctta
    12301 cctgtataaa acttgtatac tgtaaaacct tcatttttta aatatacttc aattaaatct
    12361 gctatttctt tttcatcatc cacaatcaaa atattttcgt tcatagatta tttttcactc
    12421 tccttattat cgaggtcatc atttataata ttggtaaatt tacatatcaa ataattacaa
    12481 gcatatttgt aactaatttt tataagaaaa gaactactac atcagaatgt gttgatgcta
    12541 ctattggaac acaaaaactg agattaattg ttattataaa aactccccta acacgtcctt
    12601 attatcgcat aacaggtatt aactttcaat aaaaatatct atcagtcaaa cacaattcaa
    12661 tttattatac cagagacaat ccatataaaa aacaattaaa cctatgtatg taaccacaga
    12721 cattactaaa atttccatgt tattttatat aaaaattcaa aaaaggagtt gaatttaaaa
    12781 tttgattaga aaaaaatcaa ttttgagaca actccttttt attttaatgt atttaaatta
    12841 tagtatatca gccttcataa tatcctcaaa atcacctttt tcagatatta atcttatcaa
    12901 tttaacagta cagcttaaat catttataag tatagctcca actaatgaac catctttcat
    12961 aaataatttt ttatatattc tttgaccttc atcttttgat gaaatttctt tatcaaaatt
    13021 ttgtatatta ccaatactaa atacttttac attcattgca tctaatgaaa ctggatatac
    13081 ttcactttca aatgtcaaat tatctccact tgcatttgcc cctgctattt ttcccatttc
    13141 tactgaagat ggccatattg ctaaactaat atttcccact tgtgcaacat ctccacaagc
    13201 atatatatct ttaacatttg tctgtaatgt cttatctaca acaatacctc tatcaatttt
    13261 tacagatgta tcctgaacca tttgagtgtt tgctcttaca ccaattgaaa atactaccat
    13321 atcacagtcg acactatctc catctttaaa tacaactttt tgagcttttc catcaccttc
    13381 aataccatca actgctacac ccaatcttac atctattcct gtatctctta cacattgttc
    13441 taatatttta ctaccttctt tatcaagttg ttttgatagt atgctatcca tggcttcaac
    13501 tactactact tctaatcctt ttagtctaaa ttcccatgca gcttcaagtc ccaataaacc
    13561 gccaccaatc actacaactt tcttagattt ttctagtgct tcttttacac tatataaatc
    13621 ttttatattt ctaagagtaa acacattttc taaatcatgg cccttaattg gtggtataaa
    13681 gtttctactt cctgtagcta ttacaagctt atcaaattta atagctccat cattcactat
    13741 aatagtttta ttcacttcat ctaatttatc tacattcgtt cctaatatta ctactatatt
    13801 atttttatca taccaatctt tatcttccat gtagaaatct gaaccaagtt cttcatttat
    13861 accatcagaa agtgcaggtc tatagtaagt caactcatct tcattagaaa tcatagttat
    13921 cttacaagtt ttatttcttt ttcttatagc atctgctgca taaaaaccag ctgctccatt
    13981 tcctactatt acgaaatatt catcagtatc ttttctaaaa gtaacttcat cttcttcaac
    14041 ttctataaat tggtcttcct tagctccaca tacagggcat acactaggag cactatcacc
    14101 ttcaaaaact tcattacaaa ttacacattt aaatttctta gttttctttt tacttccaaa
    14161 agtagaattt aacttatcta ggaatttacc tgtataagaa tataatttat caatctcttc
    14221 atttgatggt ttaaagttaa cagcaaaagg ttttactgct gtcattctaa gctgacttat
    14281 tctctccata gcattttcta taccttctcc actccatcca tatgaaccaa atactgaagc
    14341 aacttttcca ccatgaagaa ctgggtttaa cgatattaat atatcccata taggctttaa
    14401 cgcatctcct aatattgttg gtgttccaaa taatacacct tgtgatactg ctatttttgc
    14461 caaaatatct tcttgcttat gctctattac atcaaataaa tttactttat agttgctatt
    14521 tttttcaata tatgctttta tagcttctgc cataatcttt gtatatccat gtgcagaaac
    14581 ataacaaatt gtaacttctt tttctaactt tatttgttca tttacactcc agttgtaata
    14641 aaggtctata atttttctag gattttcagt taatactgga ccatgacctg gacatacagt
    14701 atctatatct aaatctttta tcttttctat agcagttacc atagatggtt taaatggacc
    14761 cattatacaa tcataatagt atcttaaagc atccaagtaa tccttttctt cattttcatc
    14821 aagtgtattt actatcttat cattactata gtgactacca aatgaatcac atgttacaag
    14881 agttttatcc tcttttatat atgtgtatat ggtatctggc caatgaagca taggtacaga
    14941 gaaaaattct aaagttttgt ccccaattga taatgtatct ccatctgtaa ctgcaacata
    15001 ttcaaagtct ttgtttacga tttccttaag atatttaatt gctgtttctg aagctactac
    15061 ttttgcattt ttagctaaat ccaaaagctt ttcaacgctt cctgcatggt ctggttcagt
    15121 atgacttaca acaatatagt ctattttttc aaaatctata tttaaatcat ttaatctttc
    15181 aatataattg tcaaaatgct tatctttaac tgtctcaaat aaaactgttt tttctgttcc
    15241 ttttaataca tatgaattat aagtagttcc ataaggtgta tacataatta tgtcaaatac
    15301 tcttaaatca gggtcaagcg aacctaccca atataaattt tcttttattt ttagtgattt
    15361 caatgacata ccgtactcct cctaaaatag ttatttagtc tctttatacc ctgcttgtta
    15421 tattttaaac aaaatttatt caaaaaagaa attattttaa agatagttta aatcttctaa
    15481 tcttcttttt ctaccttcaa tacagttccc tttttagaat ctacttttat gtcatattca
    15541 tttttatctt tatctattct tattttataa aaagtaacat ctaaatcttt gtctaaactc
    15601 cattctttaa ctattccatt ttgttctttt aatgcaattt ccatagcttg ttgaggtgtc
    15661 attatgtcat ttaaatctaa tttttctttt ctagcaactc catttaaatc ttctgaatcc
    15721 aacttttctg ttttatcttc taatacatct tttgtattag catcaatttt catcttatat
    15781 tcattattat catctacacc ttccacagta taaacaaatt tatttaaatc tctctcaaga
    15841 cttaaatcta ctatatcagc atccttatat ttatctttaa atatgtttat tgcatctgtg
    15901 tatggcactt taaaatcttg ttccattaaa ttttcattat ttttttcatc ttttaaagcg
    15961 ttatttgatg catttgcctc cttttttgta ttatcttgtg cttgtcctga atccttagtt
    16021 ggactcccac tacatgcagt taataaaccc gctataagca tacttaccac taataaatac
    16081 gtttttttac acataaaaac cctccttaaa tatattaatt tattctatat tatgccctct
    16141 aaacccttta tttacccttt tatattaaaa attcctccta ttttatcaat tttaaaactt
    16201 tatatttact aaaattaaag ttacataaaa attatactgt ctcaaaatgg aaacaagcct
    16261 ctttttcatt gttgaaataa taaaaatata ttttatttcg tacaaaaaga gtgcctcatg
    16321 aactaaaaag ttcattttga gacactccca tttttttata tttttactta caaaataaca
    16381 gtacttatta attttttaca aaccttataa gtatatctat atgatattct taaatttaaa
    16441 cactatatta aaaaattaaa ttttgtttaa ttcttttacc gttaaatcca ttttaggata
    16501 tggaatcgta attccttctt cgtcaaacct aactttaacc tcttctagta aatcaagata
    16561 aattgtccaa taatcttctg tcttgcacca aactctagtt gcaaatttaa tagcattatc
    16621 tccatgttct actactccta taaatggttc tggttcattt attattaatt tatgattatt
    16681 aacaatatct ttaagtactc ttctaacatg tagtatatca tcttcatacc ctacactaaa
    16741 agtcaaatca actcgtctag tattctttgc tgaatagttt attagactat catttgatac
    16801 agaaccatta ggtataagta tctgtttatt atctggagta accaattgtg tataaaaaag
    16861 acctatttgt tcaaccgttc ctccatgacc tgctgcttct acgtaatctc ctactttaaa
    16921 aggtctaatc aatagtataa taaatcctcc agcaaaattt gatagactac cttgtaaagc
    16981 caaacctatt gctacccctg ctgatgctat cacagcagca aaactggaca aactcattcc
    17041 ccaatattcc agaacaatga ttataacggc aactttaagt acactcaaaa gaagagactt
    17101 taaaaacttt cttaaagtta aatcaatatc tcttttacta agtaataaca taacatggtt
    17161 tacaaatttt tttattattt taaatccaat agaaagtata agtatgccta ttataagttt
    17221 tactccgctt gtagtagccc attctagcag actttccatt atacctccca tatccatctt
    17281 attaatatct aaattattta aatctaactt gcttatatca tctattttcg tcgtatccat
    17341 aaaaaactcc ttaccttata ttttagaacc aatattatag tttaaagttc ttattttcta
    17401 tttaatataa tacaatacca tttgtacata gtaaacaaga tttatattcc aattatacat
    17461 attaggaaaa tgcaaactat ttgttatata tatgcaaaat ataatactaa attaaactat
    17521 taataaaaca ctatatagcc ttaaaatcat cattttttac ccctatatga gatgatacta
    17581 tagttataat acttagtact ataaatacta caaaaccttt tttatatcca tcaactatat
    17641 tatatgaatt tacttgtaaa gagatagcta taatcaaatt aataattcca cttcctataa
    17701 attcaaaagt attaataaca ctagttgcca gtccagaata aatttcttta tttttatact
    17761 tggcatcatt aaaaacctgt agatgtgaca taactataca tcccataata aagaatgata
    17821 ttggtaaaac tataattggt ggttttacct ggtatacaac tacaattaca atccatataa
    17881 acaaatctat cattgctcca aattttatta tattaaattt gctagacctt attttagcaa
    17941 atacaaaatc cataattatt gaaccaaata taaatccata tgtaaaaaat gatactataa
    18001 acgcagaaaa actcttactc acaccataaa cgtccattat gtatcttact ccccacaagc
    18061 ttataaatgc acttgtaaga ccaacaaaag agaacattat cattgaatta taccatgttg
    18121 atttgttctt tataacagac ttaataccat caacaatatt aaccttctct gacttttcat
    18181 agggttcagt atctacattg aatccatact cttttggtgt atctctaaca ataatataca
    18241 taaaacatcc aattacaaca ccaattatac cgattaataa aaatgaattt ctccaaccaa
    18301 caagttcaga caaaaacaca agtggaaaag tagcaagaac tccacctaaa tttcctacaa
    18361 atgaaaattt agctgttgca gaagcaaatt ctgacttatt aaaccatctc ccttgaattt
    18421 ttaaaataca aagtaatatt actgatgttc ctgcccctac aattacacga gaaatatatg
    18481 ctaattctat actttgaatc aaaccaaata aaattgaccc taaacttgcc attattattc
    18541 caagactgct aatttttctt gctccatatt tatcaatcaa aattcctgca ggtatttgca
    18601 taaatgcata tgcatatagg caaaaggatg ctatatttga aatttgtata gaattaaaac
    18661 ctaactcatt tgctaaattg tctgaaacaa cagcagttga catccttaaa aataatacta
    18721 aaacaaatga aaatgtaatt ataccccaaa cactccactt agcctttgta taacttttca
    18781 tatcttctcc ctcaaatcca tatattttta aattttcttg atataactta tataaagtgt
    18841 atagttattc ttacaaattt ttacacgcaa tatcattata caacatatgt atatatttaa
    18901 ctagaaataa aacactattc atattatata catgaattaa ctacataaat aataagagcc
    18961 atcttttaac attactcaaa agatagctcc atataaaaac atttattcta aatttaattt
    19021 tttatctaat ataaattttg tagcgaaaaa taacgctatt gcaactacaa gactaccaag
    19081 tattgcaagc ataaaactag gactctgata aagatgatat accatatttg tatcttcatt
    19141 tggtaagatg cttccaactg catctccaac aattgatatt actatattta tagctataaa
    19201 agaagcaaat gccactatgt ttctatgttt attgaatttt ggcaattgtc ccattgagat
    19261 tgatgtatat aataacaaaa taaatgatga atatgaaata aacattacta ctactaataa
    19321 taaaatatct aaaaagtttt cagaaatcca tttaaaacta gtgttaaaca aatctaaaat
    19381 ttcaggtagt aaaattccag aagtaccaaa aagcataaga actccaaaag tgaatactgc
    19441 aactataaaa ctaagtacag cgtatataag tgctgttata catttagata atataagtga
    19501 actagtgcta acaggaagag taaacattaa ataaccttca tcccccaaaa gattttttct
    19561 aaacctttga attgtaacta caatagttaa aactcctaat gccataaaaa gacttgttaa
    19621 tactagtatt cctattccct gtacctgaag tatatttgta ttcataaata ttccattaaa
    19681 tacagctact atcaatatgg ctatatataa cggtataaat attcttccac ttgcttttaa
    19741 ctcatatttt aataatttac ctaacattta aattcctccc taaataatgc atctatagat
    19801 tttccttttt cttctcttat tgcttcaacg tctccttgta acactatttc tccttttgat
    19861 atgaatatta tctcatcaca tatgttttct atttcactta ttaagtgggt agcaatcagt
    19921 aaagtactat cttcagaata attttttaat atagtcttaa gtatatatga ccttgcagct
    19981 gggtcaacac cacctatagg ttcatccaat atatatatgc tcgcatttct tgacattact
    20041 aaaataagtt gaactttttc tttagttcct ttagacattg tctttagctt ttcatttaca
    20101 tcaatatcta agcttttaat catctcattt gctcttctaa catcaaaatc actataaaaa
    20161 tcatagaaaa acttaagtaa atctgatacc ttcatccaat catttaaata agttctttct
    20221 ggtaaatatg aaactatttt tttagtatct atggatggtt tcattccatt tatcataatt
    20281 tcaccattat caggctgtaa taatccattc attagcttaa tcattgtact tttgccactt
    20341 ccattaggtc ctaacagccc gactattttt ccctttggta tatttaaatc aatatttttt
    20401 aaaacattct tagttccata actcttgttt acacctttaa attcaactat tccatcttga
    20461 gaaacattgc ttatattttt atccatttta taattctcct ttcagatttt ctgtaataag
    20521 ttttagcatt tcatctctat catatccaag cttttctaag gttactttta atgtatttat
    20581 ctccacatta gctatttcct ctttcatagc ttttattttt tccttatcat ctgttacaaa
    20641 tcttccttta gttctctgac tataaactaa accttgtctt tcaagttctg ttagagcctt
    20701 ttgcattgta tttggattaa cttccgcatc ttctgctagt gctctcactg tttctaattt
    20761 agatcctatt ttaatttccc ctgaaattat ttttaacttt aaatgttcta ctaattgtat
    20821 atatataggt ttgttattat caagttccca ttccatgttc atgcctcctt attatattat
    20881 tgtattaagt tgttaataca ataatataat aatacaaagt atatgtcaat tactttttag
    20941 taaaagtata aaaaatttta caaaaaaaat gaacactaca ttagagtcca tttttaacac
    21001 aatttattaa attctttata ttacagatta attaccctct taccaagtta gatacaatta
    21061 aatgttcaaa ttcttcaatt ggcattggct ttccaaacaa atatccttgt gccatatcac
    21121 actttacttc ttttaaaagt ttaaactgtt cttctgtctc aactccttct gatatgactt
    21181 tcatacccaa ctcttttgcc atttctatta ctttagtaac aattattttg cttcttttac
    21241 tattataagt ttccataata aatttttggt caagttttaa gatatccata ggaatttctt
    21301 ttaacatatt taatgatgag taccctgaac caaaatcatc catagatatt aaaaatccta
    21361 ttttttttaa attattcatt atatcaatta aaatatcaaa attatcaaat atgatactct
    21421 ccgttaattc aagttctata tactttgcag gtatattgta tttatcaatt atatttttgt
    21481 atgtttctat aaaattattg caatataaat gtatccttga aacattaact gaaacagtaa
    21541 ctggatttat tcctgcatca atccattttc taaggtatat acatacttct tcaagcacat
    21601 ataaatctaa atttataaca aaaccgtttc tttcaaaaaa tgggataaat tcatttggag
    21661 gtattagccc tttatcagga cgtttccacc taacaagtgc ttctgaacct tgtatctctc
    21721 ctgtattaag ttctatctta ggttgtaagt atataataaa ttctttattt tctagacttg
    21781 aaaacattgt attttccatc tctttttctt ttatctcttg gtcatgaatc ttattatcat
    21841 aaaatgcata tgaactttta tgtcctccct ttgccatttt atgaggtata ttagccctat
    21901 ctatgattga gttgatatct ctatcttctg gaagtataaa atagattcca caacttaaaa
    21961 ctaacttata tttttcttct tgattattat taaacaagtc taattcttca aatatagttt
    22021 ttaacctctt tgttatatct tcttcttcta tatatttcat aattataata aaattatccg
    22081 cagatattct tgcaaacatt tcctcttcaa atatattgct cttaataatc tttgttaaat
    22141 tacgcaaaat ttcattccca acttcatatc caaataaatc atttatatat ttaaatttat
    22201 caatatctat atataataaa gcatacttta cttgagtatt tttacatagt attttgttag
    22261 catcaattac aaatttatct atagtatttg ctcctgtaag attatctgta tatgctatcc
    22321 tttgcaattt aattttaaaa tttaatttat catatattat atagaatata agtattacac
    22381 atattatagc cataataagt attatttgta ttgcatgttt gctaataagc tgattattag
    22441 acacaataga ctcaaagtta tttatggagt tgtttttata gagtttgcat aaagaataga
    22501 ctggtgttgt gtatgtaatt tgtaaaatta tacaaataaa taaaaaaaac atcaattttt
    22561 tttgtaaatt cctcataaaa atttcctccc attaaaacac ctctatttta ttagcaaata
    22621 agtacatctc aaaagtttcc atttcttgta aaatggatag tttatatcta ctttaatttt
    22681 gtaaaatttt ctgctactat aattatagaa tgtagcatat tcattgtctt aactattgat
    22741 ttatatattt catataggta taatagaaaa taaatt
//
LOCUS       DAMJWC010000057        22117 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMJWC010000057 DAMJWC010000000
VERSION     DAMJWC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.057"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            74..415
                     /locus_tag="PC503_002696"
     CDS             74..415
                     /locus_tag="PC503_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF2528662.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            566..979
                     /locus_tag="PC503_002697"
     CDS             566..979
                     /locus_tag="PC503_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF2528663.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1181..1822
                     /locus_tag="PC503_002698"
     CDS             1181..1822
                     /locus_tag="PC503_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2528664.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1846..3099
                     /locus_tag="PC503_002699"
     CDS             1846..3099
                     /locus_tag="PC503_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2528665.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3145..3795
                     /locus_tag="PC503_002700"
     CDS             3145..3795
                     /locus_tag="PC503_002700"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF2528666.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3846..4442
                     /locus_tag="PC503_002701"
     CDS             3846..4442
                     /locus_tag="PC503_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2528667.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4455..5294
                     /locus_tag="PC503_002702"
     CDS             4455..5294
                     /locus_tag="PC503_002702"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF2528668.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5539..6693
                     /locus_tag="PC503_002703"
     CDS             5539..6693
                     /locus_tag="PC503_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF2528669.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            6999..8696
                     /gene="ade"
                     /locus_tag="PC503_002704"
     CDS             6999..8696
                     /gene="ade"
                     /locus_tag="PC503_002704"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF2528670.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            9048..9512
                     /gene="bcp"
                     /locus_tag="PC503_002705"
     CDS             9048..9512
                     /gene="bcp"
                     /locus_tag="PC503_002705"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF2528671.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            9522..10265
                     /gene="yaaA"
                     /locus_tag="PC503_002706"
     CDS             9522..10265
                     /gene="yaaA"
                     /locus_tag="PC503_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF2528672.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            10393..13050
                     /locus_tag="PC503_002707"
     CDS             10393..13050
                     /locus_tag="PC503_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2528673.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLVTIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      13104..13206
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            13316..14581
                     /locus_tag="PC503_002708"
     CDS             13316..14581
                     /locus_tag="PC503_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF2528674.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            14611..15501
                     /gene="metA"
                     /locus_tag="PC503_002709"
     CDS             14611..15501
                     /gene="metA"
                     /locus_tag="PC503_002709"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF2528675.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            15992..16435
                     /locus_tag="PC503_002710"
     CDS             15992..16435
                     /locus_tag="PC503_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2528676.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            16466..18283
                     /gene="ftsH"
                     /locus_tag="PC503_002711"
     CDS             16466..18283
                     /gene="ftsH"
                     /locus_tag="PC503_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2528677.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            18461..21163
                     /locus_tag="PC503_002712"
     CDS             18461..21163
                     /locus_tag="PC503_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF2528678.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            21197..21895
                     /locus_tag="PC503_002713"
     CDS             21197..21895
                     /locus_tag="PC503_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528679.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         8839 a         2364 c         3982 g         6932 t
ORIGIN      
        1 catatatttc cgatagatta tattgataaa aaacactaaa attaaattaa taaaagtact
       61 tggagggatg gaaatgaaag aggaaaattt tattaatgtt gaatacgagg ataaacgttt
      121 ttcaattaat agtaaagaag ttttgtacat agaaaagcaa gagtatgaag taaagattta
      181 tactgaaagt ggtaattatg aagttggaga aaatgctcct tgtataagaa aactattgaa
      241 agaagaaaat tttttcaaat gcagtaatag ttatattgta aatctagaca agtgtgaatt
      301 ttatctcagc aataattgta tttttgtgaa taataatttt ataagaattt taggttcaga
      361 aagaaaaaag aaattaaaaa agaaattaga aaaattatat gattatgaag attaatattg
      421 ggaggctgta ttttatacag cctctttatt tattgattgt attattaata aattttaaat
      481 tatgataaaa tataaaacaa gtaacttatt tcagaataaa atacttttta aaagaaaggg
      541 acgagatatg ggagattata ataaaatgct tgaattaaag aataacttag gtatcagtga
      601 aagaaagtta aaatatcctt gtatctataa acatttcaaa gggaaatatt atgctacaat
      661 gggtcttagc aaggctattg atgatataga aaacatatgt gaaatatatg gtaaagaaaa
      721 tttaatccaa aacagaaata aatataaatt agttattaga catactgaaa gagaagaaga
      781 tatctatgtt tatagggatt tagatggaaa cttttatcat aaaaaagaag aagatactaa
      841 tgatttagtt ttatacaaga ccttatatga tgatacagga atatttgcaa gacctttgga
      901 tatgttttta gaaaaagtag atacagataa gtatgtcaat tcaattcaag aatacagatt
      961 tgaagaagta tataaataat ataagagaaa tatgtttata aatttagaaa aattctttaa
     1021 cagtacaata atttgcagaa atacaaatga gatttattgt aaataatatg ttagattaga
     1081 ttataaaata gaaacaaagt aaagtattat atgatataat taagttttga gaagtgataa
     1141 tttatattta ataaaaaata ggcatatatt aggaggacat atgggaaata ctttttatat
     1201 agtaagacat ggacaaacgg attggaatat attgggaaaa acacaaggtc atggtaattc
     1261 tgaccttacg cctcaaggta tagaacaggc aaaagaactt tctgaagata ttggcaagta
     1321 ttcaattgat tatattttta gtagcgacct tgggagagca atgcaaacag ctcaaatttt
     1381 aggagataag ctcaatattg aagttcaaaa aactgaggca cttagagaaa tgggattcgg
     1441 agtttgggaa ggccttttaa taaaagaaat tcaaaaagat tattcagata tatatgcaac
     1501 atggagaaat gaaccacact tagtaaatat accagaaggc gaaactctta agattataaa
     1561 ggaaagagta gatgctttta taaaggaact aaatgaaaaa tatgataata aaaatataat
     1621 tcttgttaca cattcaatta cattgagggt tatgttgttg tcatttttag aatcaggtat
     1681 ggaaaatata tatagaatta agcaagataa tactgcttta aatatagtag aatttaaaga
     1741 ttatgggcct gttatagtaa aaatgaatga tacaagtcat ataaaaaatc atgtaaagat
     1801 aaataattct gcactggagt aggaatcaat tataaggaga aatttatgag taaagttata
     1861 gtagttggtg gaggagcttc tggaatgatg gcagctttgt cagcttcaaa aaacaataat
     1921 gaagtaatat tagttgagag aaatggagaa ttaggaagaa aacttagggc aactggtggc
     1981 ggtagatgca attttaccaa taatagagag atagaagatt tttttgataa agttgtcagt
     2041 aataaaaaat ttctctatag tagtttttat acatttacaa ataaagacct tatttcgtat
     2101 tttgaaagta gaaatttgga atataagatt gaagaagaaa atgaccacaa agtatacact
     2161 aaaaatgata aatctataga agtaatagaa gtattaaata aagatttact caatcacaat
     2221 gtaaagataa tgtataataa gaaagttata gatattataa ctgaagaaat tgctctaaaa
     2281 gatgattcta ataaggacaa gtcaaagtat ctaataaaag ggattatttt agataatgga
     2341 gataaaatac taggagacaa ggttattata tcaactggag gagtgagtta ttcaaagacg
     2401 ggttcagatg gttcaatgta taagattctt aaaaagcatg gacatacatt aaacaaacta
     2461 tatcctgctt tagttccact tacaatagag gaaaaatgga ttaaagattt acaaggaata
     2521 tccatgaaga atgtggaaat atcttgtaag attaagaaaa ggaaaatatc aaaatctgga
     2581 gacatgctat ttgcccattt tgggataaca ggaccttgtg ttcttataat gtcttcttat
     2641 attaacaaga ttattgaaaa ggaaaaggta gaattaaata tagatttctt accaaattta
     2701 agtactgatg aaatctctag tataatcaga gcatttccaa ataaaaatgt tctaaataat
     2761 cttaagcaaa tactacctca aaatttctta aaagagattt tttctctatt atctttagtt
     2821 gataaaaagg caagtgattt gtctaaggca gatgaaatta gaattattga gtatataaaa
     2881 aatatgaagc taacttgtaa tgggactaca ggtataaaca ctggtatggt tacttctggt
     2941 ggtatttcag ttaaagaaat taattcttct actatggaat ctaaattagt taagaactta
     3001 ttttttacag gtgaagtaat tgatatagat gcagaaactg gtggatataa tttacaaata
     3061 gcattttcaa ctggatatct tgcgggtata agtgtataaa tataattttt taataattaa
     3121 atatgaataa atagaggtgt atatatgggt aatttagtta tagctgtaga tggtccagca
     3181 ggagctggaa aaagtacaat agccaagata gtagcaaaaa agctaaatat aaattatata
     3241 gatacaggtg ctatgtacag agcagttact tataagtgtt taaaaagtgg tattgatgtc
     3301 aataatgaaa aagaagttat tcaaatagct gaaaattcgg atatagattt taaagataac
     3361 aatatatatt tggacaaaga agttataaat gaagaaataa gaacaataga agtaagcaat
     3421 aatgtttcta atgtagcaaa aataaaagaa gtaagacagt tgatggttga agttcaacga
     3481 aaaataggaa tgaaaaattc agtaatacta gatggtagag atataggttc atatgttttc
     3541 ccagatgcag attacaaatt ctttttagta gctactccag aagaaagagg aaatagacgc
     3601 tataaagaac tttgtaataa aggatataat actactttag aagaagtaat tgaggatata
     3661 ataagacgag atgaaattga ttcaaataga gaatttgcac cattggtaaa agctaatgat
     3721 gcactagaaa tagatactac aggaaaaact atagaagaag ttgtagaaga agttgtatct
     3781 aaaataaatc tttagttttt tatgcatcat aatgaaaata aatgtagtgt tgaagggaga
     3841 taaacgtgaa tttttataga tttgtaataa atatttttaa gggtttttct aaaatatttt
     3901 ttaaatatga agttataggt gcagagaata ttccagatag aggaaatata gtaatagcat
     3961 caaatcataa atcgaatctt gaccctatat tcttggctgc tgccatagaa aatagagaaa
     4021 tagctgcaat tgcaaagaaa gaattgttta aagtaaaacc attgggattt atattaaaaa
     4081 aattgcatgt tatgcctata aatagagaaa aaccagatgt atctacaata aaaactattt
     4141 taaggtcagt tagagacggt tatgtattag gaatatttcc agagggtact agaataaaag
     4201 gagattcttt tggtaaggct aaggcaggtc tttctgtatt tacaataaaa agtaaatcta
     4261 aagttgttcc agtatcaata atatctaaat ataaactttt tagtaaagta attgtatata
     4321 ttggagaacc aatatcattt gaagaacatt ttaaggaaaa attgagtaat gatgaccatg
     4381 aaaggatatc acaagagatt ttagaagtga taaaacaaaa ttactttaaa tattcaaaat
     4441 aagggggtaa agttatgaac ataaaaatag caaaaaatgc tggcttttgt tttggagtaa
     4501 aaagagcaat gaaaatggca tgggatgaag ttgaaaaaaa tgattctggc atatatgctt
     4561 taggtcctct tattcataac aagcaagcag tagcaaaata tgaagaaaaa ggtcttaaga
     4621 ctgtgaatga aattgataca ataccaaatc atgaaaatat gataataagg tctcatggag
     4681 ttcctgaaaa tatatataag gaagccaaag ataaaaaatt aaaaattgtg gatactacat
     4741 gtccatttgt aaagaaaata catacagtag taagtgaata tcataataaa ggctatgaaa
     4801 taatagttat tggagatatg aagcatccag aagttatagg tataaatgga tggtgtgaaa
     4861 attcagctat aataataaag accttagaac aaatggaaaa tatggaattt gataactcca
     4921 aaagatattg tcttgttgca cagactacaa taaatccaga gttgtatata agtatagtta
     4981 ataaactatc agataaatta gaagaaatag tatttaatga tacaatttgt tcagctacaa
     5041 aaacaagaca agaatcagct aaagagttag ctaaagaagt tgattgtatg atagttatag
     5101 gaggtaaaca cagttcaaat actcaaaagt tagtaaaggt ttgtgaagac ttagtaccaa
     5161 cttttgcaat agagactaaa gatgaattgg atgtaaatac gcttaaaaaa tataaaaatt
     5221 tgggtattac agcaggggca tctacaccta attggataat agaagaagtt gtaacattcc
     5281 ttgaaaattt ataatttgat aggtaataaa aataggtgga cattgttata atttatcata
     5341 atatccacct ttgatttcat attacatgtg gtaaatagat aacctaatat caaaaagtgt
     5401 gtatcttaag atgaaaaact aagagtataa gatgcgcact ttttaatatt agaaattcaa
     5461 aagaaatatt gatattgatt atcaatagaa aatagaatat aatataattg ttgcaaaatt
     5521 agtctaggag gtaaattaat ggaaatgttg atatccgctt ctgaagaggc gtttttacat
     5581 gtaggttcta tgattggatt ttttattttg ttatttggat atattaatta taaaactagt
     5641 ggaaatttta ctaatatcat atcaaaaaac agaaaatttc aacccttaat aggtgcttta
     5701 attggagcta taccaggttg tggcggaagt ttggcaataa tgccattgta tataaatgga
     5761 aaattaagct ttggagcaat aattgcaagt ttaatagcta gtatgggaga tgcagcattt
     5821 gtacttattt catcaaatat taaaatgtat ttttttgtca ctatagttag tacaattaca
     5881 ggaataataa ctggacaatt agtggattac tttaaactag aagaaaaatt agggttaaaa
     5941 aaccgtagaa aatcagataa atatgatata agtaaaaata accctaaaga aaataaagaa
     6001 caacataatc atgatgaaat aattttagac actctagcta aatctcatgg aaatacaaat
     6061 agacttgcat ttataataac acatggaaag ggatataaaa tttatatagg aattatagta
     6121 atcggtttta tatttatgtc acttgctcac tctggactta atcttcctat aattgagaag
     6181 ttacattcat tggaagaagt aatagcagtg attggaatat tattttcaat aatttatatg
     6241 tggtgtttta aaaaggtatt taaaaattct aatcaaaaag aggaagaaaa taaaaagatt
     6301 tctttgcgag aaatgcttat ccattctgtt ggagaaatat catttgtaat tacatggatt
     6361 tttattgcat atcttattta cgatttgata atattaattt taggtggaga tgaatactta
     6421 gttaaattag tattatcaac aggtgtaata agtgtattta taggtgcagg tcttggactt
     6481 attccaggtt gtgggataca aattgtgctt atgtcatttt atttgaaggg aactatacca
     6541 cttggtgcag tgatagccaa ctctatttct caagatggag atgcactttt cccactttta
     6601 gcaatggata aaaaatcttc tttatgggct atgattatta ctactatacc agcaatactt
     6661 gtaggtatga tagtttatgc atttttaggt taaatataat tatgaataaa gaagtattaa
     6721 aaaaataata aagcacataa atttatttat aagaatagtg aagattaaat ataaaaataa
     6781 aaaattcaat atgaattaaa ttattgctta aatattaatg agaacatggg agataatatt
     6841 attcctcatg ttctctctat ttaattaaag gaattatgga acaaatttca agtgatactt
     6901 tctatcaaaa ctcatatata atatatatta ataaattaaa ctataatacg taatacagtc
     6961 agtatattga tataaaaaac ttaggaggag ttgtaaaaat gggtaattta aaaagacagt
     7021 gtgatgtttc aagtggaaga gaaaaagctg acattgtact aaaaaatggg acaatcataa
     7081 atgtatttac agaagagtta ataacaggag atgtagcaat agtaggagac actattgttg
     7141 gaattggcga ttacaagggc aatgtagaaa ttgattgtag taacaaatat atatcacctg
     7201 gctttattga tgcacatatg catattgaat ctacaatggt aatgccaatt gaattatcga
     7261 aaaaattatt aaaatcaggt acgacaacta tcatagccga cccacatgag ttggtcaatg
     7321 taaaaggagt tagtgcaata gattttttat tagaatcgac aaaagatata ccacttaatg
     7381 tatatattat ggtgccttca tccgtacctg caacaagttt tgaaactaat ggagttggta
     7441 aatttagtgc aaaagacatg gagagttatg taaataatcc tagaatttta ggtttaggag
     7501 aggtaatgtg ttttaatgat gttataaatt ctgaaaatga aatcttggat aaactagagc
     7561 tttttaaaaa taaagttgta gatggacatg cacctaatat aaatggtaaa tcacttcaga
     7621 catatgtatg tgcaggaata gaaaatgacc atgaatgtat aacttttgat gaagtatatg
     7681 aaaaattgag agcaggatta aaaattttaa taagagaagg aagcgcagca aaaaatttaa
     7741 agtctatagt aagtggtatg ctaaagcata acttgccaat tgaagaattt atgttttgca
     7801 cagatgataa gcacttagat gatatagaaa aacaaggtca cataagatgg aatataaaat
     7861 gtgcgattga tttaggtatg gaacctgtta gggctataaa agttgcaact tataattctg
     7921 caaaagcata tgggttaagg aaaattggag caataggtgc gggttataag gcagatattg
     7981 ttgtattgaa tgatttagac aaaatggaag tggatagtgt atataaagat ggtaatttgg
     8041 taaacgaaga gatgttttct aattacaatt atgagattaa agataaagaa ttgcttaata
     8101 cagtcaagtt taaatatatt aataaagaaa aaatacagtt aaaagtaagt gaaaaaaatt
     8161 atgtaatgga gattgtacct tatcaaattt tgacaaataa ggtatatgaa tctttaccat
     8221 gtgcagatgg atattttgtt ccaaataaag agtattcaaa actttgtgtt gttgagagac
     8281 atagaatgac tggaaatgta gcaattgctc cactaaaagg atttggcata aaaaatggag
     8341 caattgctac tactgtggcc catgattctc ataatattat agttgcaggg gataatgatg
     8401 atgatattct agtagctata aattacttaa aggaaataca aggtggttat gtaattgtat
     8461 caaatggaaa agttcttgca cacctaagtc ttcaagtagc tggattaatt agtactttta
     8521 cagctgaaga agtacaagaa attactgata atatgttgga gatagcaaga aaaatggaag
     8581 ttccagagta tgtagaccct tttattacac tttcttttat ggcacttcca gttgttccac
     8641 aaataagact tacagattta ggtctatttg atgttgagga atttaaattt atatagatag
     8701 tataaaagta ataataaatg aggctttctc aaaatagaga taagtctctt tttattgttg
     8761 aaatgatgaa aatatatttg atttcataca aaaaagagca tctcatgaac taaaaatttt
     8821 atttttagat atccttattt taattaatct atcatttaac attgttttaa gcatagatat
     8881 cttaataaaa ctattttcag tctattttaa catataaata catgaaaatt atatatttat
     8941 gaaactttat acataaaaaa taaaatattt tatttatata tagatttata gggtaataat
     9001 ataagcatag tataaaatta ttaataaaaa caaaaggaga gatatttatg ttgagtatag
     9061 gaacaaaagc accagaattt acactagaag ataaagatgg aaataaggta agtatgtcag
     9121 attttaaagg caaaaaagta gtagtatatt tttatcctaa agataataca ccaggatgta
     9181 cacgtcaagc ttgtgctttt agaaatgcat atgatggatt taaaaaggaa gatatacaag
     9241 ttattgggat aagtaaagat agtataaaat cacatcaaaa atttgcagaa aagcatgaac
     9301 ttccttttat tttactttct gaccctgact tagttgctat aaaagctttt gatgtatgga
     9361 aagagaaaaa aatgtatgga aaaactgcat tgggagttgt acgtgcgaca tatattatag
     9421 atgaaaatgg aattattgaa aaagtctttg aaaaagcaaa accagacaca aatgcacaag
     9481 agattcttga atatttggaa aaacaggagt aataagaatt tatgattata atgttatcac
     9541 cagctaaaaa tatgaagaat atagaagtat ttgatagaga tttgagtttg ccttgcttta
     9601 tagataacac aaaagaaata gtggaaaata taaagacatt tggtatagaa gattttaaaa
     9661 ataaaatgaa aattaatgaa aaattagctg tattaaataa aaatagattt gaaagcatta
     9721 aatttgatag attaggaaac cctgcaatct taacttatga tggaatacaa tataaaaata
     9781 tagaagcaga aaattttaca aggaaagatg aagagtttgc aaatagctgt attcgaatca
     9841 taagtggatt gtatggtgtt gtaaaaccat atgatagtat atatgaatat agattagaaa
     9901 tgcagacaaa attacaagta ggtgagttta agaatttata cgaatattgg ggaaatcgta
     9961 tatataaaga actaatcaaa gaaaaaacag ctatcgttaa tctttcatca aatgaataca
    10021 gcaaatccat agaaaaattt attaaagata gtgatacata tattacatgt acttttaaag
    10081 taaataaaaa tggcatattg aaagtggaat ctacacaagc aaagaaagct agaggtatga
    10141 tgacaaaata cattgtaaaa aataggataa gagatattga agaactgaaa aagtttgatt
    10201 tagaaggtta taagtataaa gaaaacttat ctaacaatag tgaatacata tttgtaaaag
    10261 agtagaagtt ttgttaaata ttaaatggca ttgttaaatt taggtaaaat atacttagtg
    10321 tgtattgaat tgaacttgat tttaaaatat aattattctt aaattaaaaa aagaaaggag
    10381 tggtcttcca aaatggaaaa tcacaaacag atgccttggc attcaagagc aacgcatgaa
    10441 attttagaaa gtctagattc atcagaggag gggctcaccg ataccgaggc ggaaaaacgg
    10501 cttaaagaga atggcttaaa tgaacttaga aaaaaaccac ctagaacaac tttacaaatg
    10561 ctttggagtc aaattacaga tgctatggtt atgatactaa taggagcagc aatattatct
    10621 ttgatatttg gcgaatttac agaagctttt gtaatactaa taattgtaac agtaaatgca
    10681 gttattggaa ttgttcaaga gaaaaaagca gaatcatcat tagaagcatt aaaaaatatg
    10741 aattcaccta cagctcgtgt tatgcgtgat ggtgaagaaa atgttattcc agcaagtaat
    10801 cttgtagtag gagatattgt ttttttagaa gatggagcta tggttccagc agaccttcgt
    10861 ttaatagaaa catcaagttt aaaaattcaa gaggcttctt taacaggaga atctgttcca
    10921 tcagaaaaag atgcagatac aatcttacct aaagaatgtg tattaggaga ccgtagcaat
    10981 atggcgtata catcttcaat agtcacatat ggtagaggtg taggtgttgt agtagcaact
    11041 ggtatggata cagaagtggg taacatagca catcttttag attcacaaga tgattttgat
    11101 actcctataa aacgtaaact taatactgtt ggaaagacat taagtgtcat aggtattatt
    11161 gtatgcgttg ttatatttgc aataggtgca ttttatcaga gacctctctt gccaatgttt
    11221 atgattgcaa tttcccttgc catatcaatt attccagagg gattacctgc aacagctact
    11281 attgtaatgg ctttaggcgt acagcgtatg gctaaaagaa atgctttaat tagaaaatta
    11341 cctgctgttg aaacattagg aggagctaca gtaatatgtt gtgataaaac tggtacatta
    11401 accttaaata aaatgactgt tacacatatt gctgtcaatg gagattttga atctggaaaa
    11461 gtgacatcaa tagatactgc atctgaaaaa catccattag tgtataaaga gattgtttat
    11521 gctggtgcac tttgtaatga tgcatgtatt aatccagata aaacagatga aatattaggt
    11581 gacccaacag agggcgcatt aatttttatg gccaaaaaat ttggaataga tcaagaagct
    11641 cttgaagaag aatatccacg tgtatttgaa cagccttttg attcagatag aaaatgtatg
    11701 acaactgttc ataatataga tgaaaagatt attgcttata ctaaaggagc agtagacgaa
    11761 attcttgacc tatgtactaa aatattaact tcaaaaggtg aaagaaacat tactgaagtg
    11821 gataaaaaga atatacacga attatgtctt aacatgtcta aagatgcatt gcgtgtactt
    11881 ggttttgcta agcgtgagat ttcatctata ccaaaagaag atagtgaaaa tatagaatat
    11941 gatttaacat ttataggtat ggttggtatg attgacccac caagaactga ggtaattgat
    12001 gcagtaagta cttgtaaaga agcaggtata agaaccataa tgataacagg tgaccataaa
    12061 gttactgcca caacaatcgc tcatgagtta ggaatatgga gtgaagaaaa tactgtgata
    12121 tctggtgatg aacttgataa tttgagtgat gatgaactag atgaagctgt taaaaatact
    12181 acagtatttg ctcgtgtatc cccatttgat aaacttagaa ttatacaatc tctaaaaaga
    12241 attggagaag taccagcaat gactggggat ggtgtaaatg actctcctgc cttaaagtct
    12301 gctgatattg gtatagccat gggtataagt ggtacagatg ttgcaaaaga ttcttctgac
    12361 atgattttaa tggacgatag ttttacaaca attgcttatg caataaaaga aggtagacgt
    12421 gtatatagaa acatacaaaa agttatacaa tttttgcttg ttggtaatat agcagagata
    12481 cttacgttgt ttgtagcaat attattaaat tgggatactc cgcttcttgc tgttcatatt
    12541 ctatgggtaa accttgcaac tgctacgctt ccagcccttg ctcttggagt tgacccacca
    12601 agcagaaata taatgaagca ccagccagtg aaatcaacca ctttgtttga aaaaaatctt
    12661 atacaaagag ttgttaccca aggtatattt gtggcaataa tgactatttt agcatataaa
    12721 attggtctta atatagaaaa tcattctgta ggtcaaacaa tggcattttg tgtattagca
    12781 ttttcacaga tgttacgagc atttagtcag cgttcaaata cagattcaat gtttaataga
    12841 aataatggta aaaatccatt tcttttaatc tcatttttaa cttctgcatt tttaatagca
    12901 gtaatactat ttgtacctgt ttttagaaat gcttttaact taacagtttt aaataactta
    12961 gagtggcttg taacgattgt tttagccata atgtctgtaa ttcaagtaga ggttgggaaa
    13021 attattaaaa gaaaaaaatt aaaaaaatag ttgacaaaat taggaaaaat atataagata
    13081 taaaacatag aaaaattaaa taaatcttat ccagagaggt ggagggactg gccctatgaa
    13141 acccggcaac cagtatattt atatacattg gtgctaaatc ctgcggcgaa agctgagaga
    13201 tgagtataat taagcttata cagagcctga gttatatact caggctttat ttattttaac
    13261 tctcatctgg taaatagttt aatttttttt actaaaatct aagggggata caagaatgta
    13321 taataaagaa acaatatgtg tgcaaggaaa ttataaacca ggtaatggag aaccaagagt
    13381 actaccttta tatcaaagta caacttttaa atatagcagt atagaccaac ttgctgaatt
    13441 atttgattta aaagttgatg gacatatata ttcaagaata agcaatccta ctattcaagc
    13501 ttttgaagaa aaaataagtt tactagaggg tggagtatct tctgtagctg tatcatcagg
    13561 gcaatctgca aatatgttgg cagttttaaa tatatgtaaa tcaggagata gtatactttg
    13621 ttcttcaaaa gtatatggag gaacattcaa tttactagga cctagtctta aaaaatttgg
    13681 tatagattta atatcgtttg acttagattc aagtgaagat gagatagtag aacttgcaaa
    13741 ggaaaatact aaggttgtgt ttgcagaaac acttgcaaat ccaactcttg aagtcataga
    13801 ttttgaaaaa atagcaaatg tagctaagag aattaatgtt ccatttattg ttgataattc
    13861 attagcatct ccagtgcttt gtaacccttt aaagtatgga gcaaatatag ttactcattc
    13921 taccacaaaa tatttagatg ggcatgcttc aagtgttgga ggaattatag tggatggtgg
    13981 aaactttaac tgggataatg gaaaatttcc agaattagtt gagccagacc caacatatca
    14041 tggtataagc tatactcaaa aatttggaaa tgccgcatat gcaactaaag caagagttca
    14101 gttgcttaga gactatggaa attgtttaag cccattcaat gcgtatctta ctaatttaaa
    14161 tgttgaaaca ctacatctta gaatggagag acatagtgaa aatgcactta aaatagctag
    14221 atttttagaa aaacatgaaa atgtagattg gattaattac ccaggacttg aagataacaa
    14281 gtattatgag aatgccaaaa agtatttatc aagaggatgt agtggtgttt tatcatttgg
    14341 agtaagaggt gggttagaaa atgccaaaaa atttgtggaa aaattacaga tagcatcttt
    14401 ggttacacat gtttcagatg taagaacttg tgttatacat ccagcttcaa ctactcatag
    14461 acaattaaca gaagaacaat taattgcatc tggagtattg ccttcactaa taagattatc
    14521 tgttggaata gaaaatgtag aggatttaat agctgattta aatcaagctt taaatttcta
    14581 atattctaag agaaagagaa gtgaaaagat atggctttaa tactaccaaa gggattacct
    14641 gttattaata aattattaga tgaaggaata gatgtaattt ataaagaaga ttttaaaaag
    14701 gaattaaagt atgaagaaaa catagacact aagatagcta tactaaatct aatgcctata
    14761 aagatagata cagaattaga tttactaaga aggatagata aaacaggatt caacgtgtct
    14821 gtggaattta ttaaaatttc aacaagagaa agtaaaagaa gttgtaatga atatgttaaa
    14881 gaattttata aaacatttga tgaagccaaa ggagagtatt ttgatggctt tataataaca
    14941 ggagctccag ttgaacaaat ggagtttgaa gaagttgatt attggaatga actagaagaa
    15001 attatggatt attctaagag aaaaactaaa tctacattat atatatgttg ggcagctcaa
    15061 gcaagtcttt acaaatacta caatgtaaaa aaacttccac taagtcaaaa atgttttgga
    15121 gtatttaagc ataaggtaga taaagatagt aaaatagtag atggatttga aaatgaattt
    15181 tttgctccac attcaagaca tactactgta aatattgaag ctttgaaaga gaataaagag
    15241 ttgagcattg tgagtcattc taaagaagct ggtccctata taattacaaa ttcaagagat
    15301 gtgttcgtaa tgggtcatag cgagtatgac aaatacactc ttgataaaga atataagagg
    15361 gatataaata aaggagataa aatatctata cctcaaaatt actatattaa tgatgaccct
    15421 tcagaagagc caactgtaaa atggaaaaaa cattcagaat tgttgtttag aaattggata
    15481 aaaaactatt tgatacaata aattttaaga gtatataaat gttaactaaa aaaatataga
    15541 aatttatagg tataaagtta atcttaatga tactttatac cttatttttt taaaatttga
    15601 ccttataata gtagttttat attttaagaa aatcacttta ggtgtatgta gatagaggtg
    15661 gctttaattt tatatatggt gcgataatgg gagactaaac ctttatagta tcaataaatt
    15721 tgtattttaa cttttaaaag agattaaaaa gggagaaatc agtgtaaaat atatatatag
    15781 attttttatt aaattttatt aaaaatatcc tgtataaaat taaatatcaa taagataaca
    15841 aaatttcaat tgaagttaca atattgtaat tgacaataaa tacttaatac tataatattt
    15901 aatacattaa acattatagt gttaagtatt tatttacagt atgcacttca gcctaaattt
    15961 gaaataaagt attttcgtag ggagcgtttg tatggatgag atgagtttta agaaagagct
    16021 actagagttg actagagata taaatatgaa atttacaact ttattaagtg atttttatca
    16081 gccacttggt attacagcag tgcaagcttt gattttatct gagttatgtg aacatggaga
    16141 gaaaaaaata agcgatttag ggaagaactt aaacatgaca aatagtaatg tatcagtaat
    16201 ctgtcaaagg cttgaaaaaa atggcttttt aaatcgcata agagatatag aagaccaacg
    16261 aattgtaaaa gtaaaagtta caaataaatc attggatata caagaacata tttcaagtag
    16321 tatttttgat agttattttg aaaatatgac cagtgaaaaa ttgcaagata tggaagatat
    16381 aatagaaggt ttagagaaat taaataaact tttaacttac attgattgca aataacataa
    16441 aaataattta aaggagaata aaattatgga tgaacataaa ccccaaaaaa ggtcagcact
    16501 ctattattat acagttataa taatagtagt aatgttttta aatgctttaa tatttccaag
    16561 tttaatggat aaaaaaatgg ttgagattga ctatggaaag tttctcacaa tgttggatac
    16621 aggaaaggtt aaatctgttg agatagaaaa taatagaata gcaataaatc catctagtag
    16681 caaggataag aatatataca taactggtag aatggatgac ccagaattgg tagatagact
    16741 aaaaaatgca aaagtagaat ttactaaggt tattcctaag gaaaattcac ctcttttaag
    16801 tattttactt acatggataa tacctatagg tattcttatg ctatttggta acttaatgat
    16861 gaagtctatg caaaagcgaa tgggtggtaa tgctatgcaa tttggaaaaa gcaacgccaa
    16921 aatgtatgta tctgctcaaa gtggaaaaag atttaatgat gtagctggtc aagatgaggc
    16981 aaaagaagct ttaactgaaa tagtagattt cttacacaat ccagaaaagt ataaaaagat
    17041 aggagcacaa atgcctaaag gagcactttt agtaggacct ccaggtacag gaaaaacact
    17101 ccttgcaaaa gctgtagcag gtgaagcaaa tgtaccattt ttctcaatat ctggttctga
    17161 gtttgttgag atgtttgtag gaatgggagc ttctaggatt cgtgatttat ttaaacaagc
    17221 aaaagaaaaa gctccatgta tagtgtttat agatgagatt gatactattg gtaaaaagcg
    17281 tgataatgga agtggattag gtggaaatga tgaacgtgaa caaactttaa atcagttgtt
    17341 aagtgagatg gatggttttg atggtggaat tggagtagta atacttgctg ctacaaatag
    17401 acctgacagt cttgacaaag cattacttcg tccaggaaga tttgatagac gtataccagt
    17461 tgaacttcca gaccttggag gacgtgaagc tatattaaag gtacatgctc aaaatgtaaa
    17521 tgtaagctca gatatagatt ataatgcaat tgcaaggtct acatcaggag catcaggtgc
    17581 agaacttgca aatattgtaa acgaagcagc acttttagca gttaagtctg gcagagatat
    17641 agtagaacaa caggattttg atgaatctgt tgaaactgta attgctgggt atcaacgtaa
    17701 aggagctgta atttcagata aggaaaagaa aattatagca tatcatgaaa taggtcatgc
    17761 acttgttgct gctatgcaaa aacattctgc acctgtccat aagattacta taatacctag
    17821 aacttcagga gcattgggat atactatgca agttgctgaa gatgagagtg tacttatgtc
    17881 taaagaagaa gcaattgata aaataactac ttttacaggt ggtcgtgctg ctgaagaggt
    17941 tatctttaac acttgtacat caggagcatc aaatgatata gaacaagcta ctaaaattgc
    18001 aagagctatg gttactcgcc ttggtatgag tgaagagttt gatatggtcg ctcttgaaac
    18061 tgtaagcaat caatatttag gaggagatac ttctcttgct tgttcttccg acactgctgc
    18121 taaaatagat gaagaggtat ttaaaatagt aaaggcttgt cacaaaaatg caattgaaat
    18181 cttagaaaat aatattgata aattgcatga acttgctaat tatttattag aaaaagaaac
    18241 tattacaggt gatgagttta tggaaatact taacttaaac taaaatgatt atacacaaga
    18301 taaaaatgcc tattgttagg catttttatt ttacaactaa attttttaaa tttatattta
    18361 aatctttaca taatcttaat cattaaaaat acatcttaac tacaatttta tatcggaatt
    18421 gatattataa tagtaatgaa tggtgtaagg aggtttttta atggatagac ctaatcctga
    18481 tattctatta gaaaaaatta aaaatgaaga agaaaaacta agtagaggtc aattaaaaat
    18541 attctttggt tatgcagctg gagtaggaaa aacctactct atgttggaat ctgcacaaaa
    18601 tttaaaaaaa gtgggtgtag atgtagtagt tggatatatt gaaccacaca ctagaccaga
    18661 aacattggct ttacttgatg gcttggaaat tcttcctgta aaggagatag aatataaatc
    18721 tataaaacta aaagaatttg atttagatgc tgctttagca agaaaaccag aagttatatt
    18781 agtagatgaa tttgcccatt ctaatgttgc tgggttaagg catacaaaaa gatggcaaga
    18841 tatagaagaa ttgctgttag caggcataaa tgtctacact actgtaaatg tacaacattt
    18901 agaaagtcta aatgacattg ttgagataat tacaaacgta tcagttaaag agactatacc
    18961 agataagttt ttggatacaa atacacagtt agaacttata gatgttgaac ctgatgtact
    19021 tcttgaaagg ttcaatgaag gtaagatata taagaaagaa caagctacta gagcaaaaaa
    19081 taattttttt ataaaagata acctggttgc acttagagaa attgcactta gaaaaacagc
    19141 agagagagtt aataaagaag ttcaaatgac cagactatca aagggtgatg taactgtaat
    19201 acctacatca gatacacttc ttgcatgtat aagtccatct ccatcttcag caaaagttat
    19261 tagaactgca tccagaatat cagacagtac atttgcaaaa tggatagctt tatatgttga
    19321 aactccaaac acagcaagac ttccatttga tgaacaaaaa caactacaaa ataacctaaa
    19381 attagctaag aaattaggtg gagaaataat tgttttacat ggtgaaaata taatagagca
    19441 aatacttaga attgcaaagc tgagaaatgt aacaaaaatt gtaataggta gaaatcattc
    19501 aagtaataaa agatttagta aaagatttaa aaaagatata gttgacaaat taattgatga
    19561 agttgattat atagatatac atataattcc atataaattt gcctcagatg ttaaatacaa
    19621 acctaaaaag gataaatcat caataaaatc taaatttaaa attagcaaag ttgattttat
    19681 aaaacttata tttattactt tgatgataag tattttagca tatgcagtac aaagcatggg
    19741 atttataaga gaaaatatat tgttaatata tatgttgggt gtagttttag tttctatgtg
    19801 gactaaaggg tatagtacag gtataataag ttctgtattt aatatagttc ttttaaatta
    19861 tttttttaca gcaccattat atacattatc tatagcagat tcaaactata tagtaacact
    19921 ggttgtattc tcaatagtag gtataataac tagcactctt acgtctaaga tacagcatga
    19981 agcagaaact gctgctaaaa gagaagaaaa tacaaaaatg atatatcaaa taattaaggg
    20041 atttttaaga ttatcaaata aagatgatat agtaaacaaa ggtatagaac ttttgtctct
    20101 tagcttaagt agagatgtaa tttgttattt aaatgtagat aagcataata aatcaaagct
    20161 ttacaaaaaa aatactaata ataaggataa aaatgatttg gatagtgaag atgaaaaagc
    20221 tgttgcaagt tgggttttat ccaattcaac agtagcagga aatgacacgg atacacttcc
    20281 tggttcaaag ggatactata taccaattgt aggaatgaat ttaactttag gagtagtggg
    20341 aatatcatgt attgattcaa aattggatac agaagatata agcttaattg aaacaataat
    20401 tgctcaaatg gcaatagcgc ttgatagaga aatcttgtca gaagctaaag aaaataccaa
    20461 tcttgagatt gaaagggaaa gattaagaag taatctttta agagcagttt cgcatgacct
    20521 tagaactcca ctagcaggaa tatctggtgc agtaagtaca attataaaaa acaagggtac
    20581 tataggtcaa gatataatag atgaattact tagtggtgta tatgaagata ctcagtggtt
    20641 aataagactt gttgaaaatt tacttagtat gaccaagata gatgaaggga aattggaagt
    20701 taaaaaacat tctgaactgg ttgaggaaat tatatcagaa gcgttacaaa aaataaaaaa
    20761 aagaattgaa aatgcactta tagatattaa tataccagaa cagatattat ttgttcctat
    20821 ggatgcaaaa ttaatagaac aagttttaat taatttaata gataattctt tgaaatattc
    20881 aaaggaagat tgtaagatag agataaatgt atatgagaaa gatgattatg tttggtttga
    20941 agtatctgat aatggtcctg gtatatcaaa ggaacttaaa aagcatatct ttgacagatt
    21001 ttttactgga gaagaaggag ctaaagattc cagaaagggt gttggacttg gattatcaat
    21061 ttgtaaatct ataattcaag ctcataaagg tgaaattatg gtagaaaaca ataaagataa
    21121 gggttcaact tttaagttta gtttgcctaa ggaaaatgaa tagttttaaa ttttaaaatt
    21181 agttttggag gaagaaatga gtaaaaaact tatattgtta gtagaggatg ataagacaat
    21241 aagaaaattt atatctactg cacttttaac acaggattat gatgtcaagg aggctataac
    21301 tggaaaagaa ggtatatcta tagctgtctc atattctcca gatgttgttc ttttagattt
    21361 aggcttagaa gatatggatg gaatagaggt aataaaagct atcagacaat tttcaaatat
    21421 accaataatt gtagtttcag ctagagagca agatagagac aaggtagaag tatttgatgc
    21481 aggggcagat gattacttaa caaaaccatt ctccatagta gagttattag caagagtaag
    21541 agtagcattt agacattcac aagtagaagc tcaacaaaaa gatgatgtta aatctacgtt
    21601 tgaagtagat aaattattga ttgattttga taaaagaaaa gttattgttg atgatgttga
    21661 agtccatttg acacctattg aatataatat tctttcatta cttgcaaagt atcatggaaa
    21721 agtgcttact cataatttta taataaaaga aatatggggt agtgttatag ggaatgagac
    21781 taagtcttta agggtcttta tggcaacgtt aagacgaaaa atagaaaaac aacctgcaaa
    21841 cccaagatat ataattacag aagttggtgt aggatacaga ttaaatgatg aatagttgta
    21901 atatattaat tattagatta tgtgcttatt aatatatatt aaaattatat agtttagtta
    21961 aaataagaat gaagtgtatg tgcttgttgt cagtttagca catgcatttt attttttagc
    22021 ttttttagta tcaataattt tttagtatca ataatatgaa atatgtttta aaataagtat
    22081 atagtgtaat atgtaataaa aactttggtt aaataat
//
LOCUS       DAMJWC010000058        21942 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMJWC010000058 DAMJWC010000000
VERSION     DAMJWC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.058"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="PC503_002714"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="PC503_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF2528680.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="PC503_002715"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="PC503_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF2528681.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="PC503_002716"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="PC503_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF2528682.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="PC503_002717"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="PC503_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF2528683.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="PC503_002718"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="PC503_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF2528684.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="PC503_002719"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="PC503_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF2528685.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="PC503_002720"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="PC503_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF2528686.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="PC503_002721"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="PC503_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF2528687.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="PC503_002722"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="PC503_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF2528688.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="PC503_002723"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="PC503_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF2528689.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC503_002724"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="PC503_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF2528690.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="PC503_002725"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="PC503_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF2528691.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="PC503_002726"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="PC503_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF2528692.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="PC503_002727"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="PC503_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF2528693.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="PC503_002728"
     CDS             6989..7174
                     /locus_tag="PC503_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF2528694.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="PC503_002729"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="PC503_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF2528695.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="PC503_002730"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="PC503_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF2528696.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="PC503_002731"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="PC503_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF2528697.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="PC503_002732"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="PC503_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF2528698.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="PC503_002733"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="PC503_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF2528699.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="PC503_002734"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="PC503_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF2528700.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="PC503_002735"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="PC503_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF2528701.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="PC503_002736"
     CDS             11117..11767
                     /locus_tag="PC503_002736"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF2528702.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="PC503_002737"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="PC503_002737"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF2528703.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="PC503_002738"
     CDS             12536..12805
                     /locus_tag="PC503_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF2528704.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="PC503_002739"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="PC503_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF2528705.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC503_002740"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="PC503_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF2528706.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="PC503_002741"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="PC503_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF2528707.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="PC503_002742"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="PC503_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF2528708.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="PC503_002743"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="PC503_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF2528709.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="PC503_002744"
     CDS             14901..15848
                     /locus_tag="PC503_002744"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF2528710.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="PC503_002745"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="PC503_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF2528711.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="PC503_002746"
     CDS             16330..17163
                     /locus_tag="PC503_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2528712.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="PC503_002747"
     CDS             17151..18017
                     /locus_tag="PC503_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2528713.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="PC503_002748"
     CDS             18011..18814
                     /locus_tag="PC503_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF2528714.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="PC503_002749"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="PC503_002749"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2528715.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="PC503_002750"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="PC503_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF2528716.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="PC503_002751"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="PC503_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF2528717.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21008..21760
                     /gene="cwlD"
                     /locus_tag="PC503_002752"
     CDS             21008..21760
                     /gene="cwlD"
                     /locus_tag="PC503_002752"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF2528718.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8816 a         2563 c         4494 g         6069 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc tagatgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tatcccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtattaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tatagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaca tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tatattttaa gatattattt aacaatataa
    20821 attctgaata tacgttatca aaatttataa tataaactaa gtataattta ttgtatagta
    20881 ttgaatgtta gataaacata gtgaattaaa tagggacaga aatataatat cattacataa
    20941 taatatatta ataccaataa ataaagatat atcaatatta aaaaaattta aatgtttgta
    21001 ctaatatatg gaatattata gtgtttttat aagtatacat atacagggtg atgttgtgag
    21061 aaagtacata aaacatataa tttttagttt tgcaatgata tgtctagtag tagtatccat
    21121 atttgaaatt aaaaatattt ctgaagatgt tatcaagtat atgccagtaa caaacaaaac
    21181 tataatttta gatgctggtc atggaggcat tgatccaggt gcattaaata aggataagag
    21241 tacatctgaa aaggatatta acctagcaat aacacttaag cttagagagc ttatagaatc
    21301 aagtggtggc cttgtaatat taactcgaga agatgacagt agcctttata aagaagaaaa
    21361 taataaaact acaagacaaa aatataatga gaatttgaaa aatagaaaag aaataatatc
    21421 taattctaat gccaatatgt ttgtctctat acatcttaat gcatttgaac aatcaaaata
    21481 ctatggagct caaacttttt atcctaaaga caaacaagac agtaaagaat tatcgaagtg
    21541 tattcaagaa gaacttaaaa gagtagtaga taagacaaac aacagagaag tcaaaccaag
    21601 ggatgatata tatcttttga aagaaaataa tattccatca gtactgatag aatgtggttt
    21661 tttatcaaat gaaaaagagt gtaaactctt aactgatgaa acatatcaag aaaaaatagc
    21721 atgggcaatc tacataggaa tacaaaaata tttaagttga aataactata aaaataggtc
    21781 taaatatgta aatagcttgt attaaagcag ttaaaatgca ttaatatagg ctatttttat
    21841 tttgacaaaa aaatatttaa aataaaagtt aaaaagttgt tgacttagaa taatatagat
    21901 gatattatat atgagtgccc aaaaggagca ccaaaataag ac
//
LOCUS       DAMJWC010000059        21735 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMJWC010000059 DAMJWC010000000
VERSION     DAMJWC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21735
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.059"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            269..1867
                     /locus_tag="PC503_002753"
     CDS             269..1867
                     /locus_tag="PC503_002753"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2528719.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(2106..4151)
                     /gene="bclA1"
                     /locus_tag="PC503_002754"
     CDS             complement(2106..4151)
                     /gene="bclA1"
                     /locus_tag="PC503_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF2528720.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGATGPTGEI
                     GPTGATGATGVTGSIGPTGATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTG
                     ATGEIGPTGEIGPTGATGPTGVTGSIGPTGATGPTGATGEIGPTGATGPTGNTGVTGE
                     IGPTGATGPTGNTGVTGEIGPTGATGPTGVTGEIGPTGNTGATGSIGPTGVTGPTGAT
                     GSIGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIG
                     NSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTT
                     EPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
     gene            complement(4829..5353)
                     /locus_tag="PC503_002755"
     CDS             complement(4829..5353)
                     /locus_tag="PC503_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2528721.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5418..6170)
                     /locus_tag="PC503_002756"
     CDS             complement(5418..6170)
                     /locus_tag="PC503_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2528722.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6201..7499)
                     /locus_tag="PC503_002757"
     CDS             complement(6201..7499)
                     /locus_tag="PC503_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2528723.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7516..9780)
                     /locus_tag="PC503_002758"
     CDS             complement(7516..9780)
                     /locus_tag="PC503_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2528724.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(10035..10853)
                     /locus_tag="PC503_002759"
     CDS             complement(10035..10853)
                     /locus_tag="PC503_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2528725.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10846..11544)
                     /gene="cbiQ"
                     /locus_tag="PC503_002760"
     CDS             complement(10846..11544)
                     /gene="cbiQ"
                     /locus_tag="PC503_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2528726.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11547..11831)
                     /locus_tag="PC503_002761"
     CDS             complement(11547..11831)
                     /locus_tag="PC503_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2528727.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11821..12573)
                     /locus_tag="PC503_002762"
     CDS             complement(11821..12573)
                     /locus_tag="PC503_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2528728.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12755..12947)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(13079..14851)
                     /locus_tag="PC503_002763"
     CDS             complement(13079..14851)
                     /locus_tag="PC503_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2528729.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14865..15794)
                     /locus_tag="PC503_002764"
     CDS             complement(14865..15794)
                     /locus_tag="PC503_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528730.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            16015..16200
                     /locus_tag="PC503_002765"
     CDS             16015..16200
                     /locus_tag="PC503_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2528731.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            16193..16894
                     /locus_tag="PC503_002766"
     CDS             16193..16894
                     /locus_tag="PC503_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528732.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16896..17819
                     /locus_tag="PC503_002767"
     CDS             16896..17819
                     /locus_tag="PC503_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2528733.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            17976..18899
                     /locus_tag="PC503_002768"
     CDS             17976..18899
                     /locus_tag="PC503_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528734.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18892..19629
                     /locus_tag="PC503_002769"
     CDS             18892..19629
                     /locus_tag="PC503_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528735.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            19640..20413
                     /locus_tag="PC503_002770"
     CDS             19640..20413
                     /locus_tag="PC503_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528736.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(20954..21562)
                     /locus_tag="PC503_002771"
     CDS             complement(20954..21562)
                     /locus_tag="PC503_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2528737.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         6935 a         3757 c         2834 g         8209 t
ORIGIN      
        1 ttaatttatt aacatattaa ttaatttttt cccaggtaga tttaatcaat ttattttaaa
       61 taaaagtaaa tttaattcga tatttgattg ggtaaaagta tatataataa taatttttat
      121 attaaatttg tagtatttat gtaagaaata aattttatat aatatttttt cactaaattt
      181 ttttcttttt acaacaaata ctcactacct tttgatataa tatttttatc aattattatt
      241 atattcaagt tttgaaagga gtattaaaat gagtttatta gttttcggac ataaaaatcc
      301 agatacagat tcaatatgtt ctgcaatttc attagcacat ttaaagaaca aactaggaat
      361 aaaagcaaca gcttatgctt taggagatat cagaaaagaa gctaaatatg ccttggatta
      421 ctttaaggta gatgcacctg aaattttaga taatgttaga atacaagtta gagatttaaa
      481 ttatgataaa gtagtacctt taacaccaac ttcatctata ttagaggctt ataaccttat
      541 ggatgaaaaa aatgttaaaa cactacctgt aacttatgat gatggaactt ttgctggtat
      601 cattactatg aaagaaatag ctaaaaatct acttcatcaa cactttacaa ctatacacac
      661 atcactatca aacatttgta aaaaccttaa tggtactatt cttgtggact gtggtgaaga
      721 tataaaaggt agagtagtca ctttatcatt tggaatggag actctaatag agactttaaa
      781 agaaggagac atagctattg ttggagatag atatgatagt attgaatatg ctattgatac
      841 aaaagttaaa cttttaatac ttactaatca tacagagatt tcaaaagatt tgctagctct
      901 tgctaagata aatggagtgt ctgttgtttc tgttgaaagt gacaattata aaacttctaa
      961 tgtaataaat caatgtagtt tcttagactc tatagaagct acagaaaatt taattacatt
     1021 caaagaagat gattatatgg atgaaataaa agagattatg ctagaaacaa acttcagatc
     1081 ttatccaata ttagatgatg ataataagtt tttaggttta gtttcaaaag gtcatctatt
     1141 aaacccatct aaaaagaatg ttgttttagt tgaccataac gaatatgctc aaagtgctga
     1201 tggaattgaa caagcaaaca tagttgaaat aattgaccat cataaacttg gtggtatttc
     1261 tactgatgtt cctatgtcat ttagagttat gcctgttgga tgcaatagta ctataattta
     1321 tcaaatgtac aaagaaaata atgttgagat accttatgaa atagccgggc ttcttttatc
     1381 tgctatatta tcagatacat tattatttaa gtctccaaca acaactgata tagataagaa
     1441 agcttgtgaa gaattaagta aaatagcaaa agtagacatg gaaaaatacg ctatggatat
     1501 gtttaaatgc ggtacttctt tagatgaata tactatagaa gaaatagtaa atatggactt
     1561 taaagaattt aatatgagtg gacatagagt tggtattgga caagtattta ccttagacat
     1621 agactctata tttgctaaaa aagatgagtt tttatcttat ataaattcga ctgattatga
     1681 caaactaatt cttgcggtta cagatataat caaagaaggt tcttatttaa tctataaagc
     1741 agaagacagc ttaattgcta acgcatttgg tgttgaaggt gttcaaggta catttgcacc
     1801 aggtgttgta tcaagaaaaa aacaattagt ccctaattta actactgcaa tcaaaaattt
     1861 taaataatat aaaattttta aataacgaaa actgtctcaa atctatattt gagacagttt
     1921 tttattatat atatatatat tgataataaa gttaaataaa aatccataaa tttaaaattt
     1981 ttatgaatat attttattat tattgttatt ttattcattc taaaataggt aaaactcaat
     2041 atataaaaat acttttgtca tttaaataaa gcctaaatag tttttaagat tattttagac
     2101 acgttttaag tcataacagt atcagctatt ctaaatatcg tcaaagtagc cgcagttcct
     2161 gctgattgcc catttcgtat ccctactgtt gtagatgaaa aattatttat tgtaaaagta
     2221 gtcccaccaa ataaaaaacc agcaaaatat ccagaaagta ctcctccgcc tcctggctca
     2281 gtagtaagcc ctgccaaatc ttttcctcct aaaattggga ataggatagc gaaagaatat
     2341 tgatttatac ttgatgaacc tggttgtaat gctactgaaa ctgatatata atacacacca
     2401 ttttcttgta ctgtaaacgt accatttgca tctactgtta tacttgaact atttcctatt
     2461 attgtttgcc aacctgttat agcatctcca ttatttagtg tttgtggaga tggtgcattt
     2521 acgaggaagt tagcaactgg ctgagaggaa ttgcctgttg ctcctgttgg acctgttggg
     2581 cctgttactc ctgtcgctcc tgttgctccc gttggtccta tacttcctgt cgctcctgtt
     2641 ggacctgtta ctcccgttgg ccctatactt cctgtcgctc ctgtatttcc tgttggccct
     2701 atttctcctg tcactcctgt tgggcctgtt gctcccgttg gtcctatttc tcctgtcact
     2761 cctgtatttc ctgtcggacc cgttgctccc gttggtccta tttctcctgt tactcctgta
     2821 tttcctgttg gacctgttgc tcccgttggt cctatttctc ctgtcgctcc tgttgggcct
     2881 gttgctcccg ttggtcctat acttcctgtc actcctgttg ggcctgttgc tcctgttggt
     2941 cctatttctc ctgttggtcc tatttctcct gtcgctcccg ttggtcctat acttcctgtc
     3001 actcctgttg ggcctgttgc tcccgttggt cctatttctc ctgttggccc tatttctcct
     3061 gtcactcctg tcgctcctgt tggacctgtt gctcctgttg gtcctatact tcctgtcact
     3121 cctgtcgctc ctgttgctcc cgttggtcct atttctcctg ttggtcctgt tgctcctgtt
     3181 ggtcctatac ttcctgtcac tcctgttgga cctgttgctc ccgttggtcc tatttctcct
     3241 gtatttcctg ttgggcctgt tactcctgtt ggtcctatac ttcctgtcac tcccgtattt
     3301 cctgtcgggc ctgttgctcc cgttggtcct atacttcctg tcactcccgt atttcctgtc
     3361 ggacctgtta ctcctgttgg tcctatactt cctgtcgctc ctgtacttcc ggttgggcct
     3421 gttactcccg ttggccctat acttcctgtt gctcctgtat ttccggttgg gcctgttggt
     3481 cctatgcttc ctgtcgctcc tgtacttccg gttgggcctg ttactcccgt tggtcctgta
     3541 cttcctgtcg ctcctcttgg tcccattgga cctgtaattc taattggaag acactcacat
     3601 ttaggataac aattatctat aattctatct tcaaatgtta caagtatata cggtttgtta
     3661 caacctctac tagatgtaaa ttcaagaatc tgataagggt aatttaaaga taaagctaac
     3721 ccataattag gatatttatt cattgcccat gcttttatag ttcccgtaat atttaaacaa
     3781 atatagttgg atgtatcact tatcccaact ggtaaatatc ccctaatatt ttccatagac
     3841 actctatcat tccatgttat agttcgtaaa ttataatatt cacttattct tttaatttca
     3901 atatctactt tttctttaaa aatatgattc ttatttgaat caatatgaat aaataactct
     3961 gcttttaata tacttttgtc ttttaatata tctggtattc tcactttaaa aaaagtaatc
     4021 aacttttctt ttacaaaact atttgaacat ttacttccta ttaagcaata atctaaatta
     4081 ctaaagtttt tatctggata ttttttagat ataaaagtat catcatttaa ataaagtata
     4141 atatttctca tttataatcc ctccattttg ggtctatatc atactatgtt taaaatacat
     4201 gcttagttac aatataatta aaatttatag tattaaattt ttatataata atgctgattt
     4261 ctacaaaaaa agaacatgtc attagaaatt tctaatagca tgttcttttt cattattata
     4321 tattacactt taaattattc cttgactggc ttagctggtg taaactaaac cagtctttct
     4381 aaaatattaa gcactttttt cttattatgt tttttaggat ttattgtcta tattattgta
     4441 aaccaaagtt ataaaattgt aaatagaata tattaccata acaatatctt tttataagta
     4501 aaaattataa aaaaccttat ttttattaaa tagaataaat aaaataagtt taaaaaatac
     4561 tgaaataagt gttttccaca tattttatat atttatttaa tacattatta tttaaaaata
     4621 aatatataaa caatcataat aaaatttttt taataaaact ttatttttta gttaaaatca
     4681 tacaatatat agatttccac aatacaaata aattaaaaag tgaaatgtat ttgtctaaaa
     4741 acataataac atttcacttt atcctcattt ttaagtaata tatattttta atttttattt
     4801 ataactaaat ctagttttta tataaatttt agtttttttc tacatctgag taatctattc
     4861 caaaagtttc tacagtaaca gatttcataa cttgtggagt ttgtggctta tcagctgaat
     4921 ctgttctaac tgatgctatt tcatcaactg tatccatacc ttctatcact ctaccaaaac
     4981 ctgcatactg accatctaag tgtggtgagt ttttatgcat tatgaaaaat tgagaaccag
     5041 ctgaattagg tgccatagtt ctagccattg atatgactcc tctttcatgt tttaaattgt
     5101 tagtaaatcc attaccacta aattcacctt ttattgagtg acctggacca cccattcctg
     5161 taccatttgg gcatcctcct tgtatcataa atcctggtat tactctatga aatattattc
     5221 cattgtaata tccttcattt actaatgata caaagttttt aactgtattt ggagctatat
     5281 ttggatataa ctcaattttg atttcttttc cattttccat ttctatagtt actataggat
     5341 ttttattttc cataatttat taccttcctt ttcattagtt aaattacata attacattta
     5401 ttatattata ctctaaatta aagtctatca agtatatttt ttcctatttc atatccttct
     5461 tgataaatag ttttacaaaa ctcatcatca aagttaagcg tgtctttagg agcaaattga
     5521 gtattaggtc taactactat tattttatct tcatcatata cttttttaat atcttctggc
     5581 aactcataat tatattttgt ggatattaaa ataattttat ccacattatc cccaattaat
     5641 ggttcaatta atgcactcct aattaaacct ccatctaatt tgaaaccatc ataaattcct
     5701 tcttgcacat ctttcacaaa ttgttcttta aatccaagag ttgcgtttgg atttgatggt
     5761 aacaacccac tgtatgaaat gctgataatg gcttcattac gaggcatttt tgatacgtca
     5821 acaatctttt ctgatactac tttattatca acttcaacat aattaacata aaagttcatt
     5881 tcttctatat tactatcatc tagttccctt aggttgtcta tagcaggaga attatccaca
     5941 gtattattta ctatttttac atttccattc tggatatctt ttatatttgt ccacattttc
     6001 tccaagttat caacattccc tgtgtacaaa taatatccat ttattgctcc tattgatgtc
     6061 cctgaaatcg aataaaattt atttattcct ccatcataca aggctttaac tactcctgct
     6121 tgataagccc cttttgctcc tccaccttct aaacataatc ctaatttcat agtctcatct
     6181 ccaaattgtt tatcttatat ttatatttca aaaaacttac taaatgtttt atatatacta
     6241 tagtggtcct caacatttcc taattctctt atagaatgca ttgctaaaat tggacttccc
     6301 acatccacag atggtatatc tatatgagta gaagatattg gacctatagt acttcctcct
     6361 ctttcatctg acctattaac aaattcttga tactcaacat tagcttctct acatatattt
     6421 ttataaatag ctatagaata tccatcacta gtatatgcct gactagcatt tatctttata
     6481 accggacctt ttcccattat tggtttatta gttgggtcat gcttttctgg aatgtttgga
     6541 tgaatagcat gagctaaatc tgatgatatc ataaaagatg aataaataga ctcaaagaat
     6601 ccctctctat ccttacccat tgatatgcaa attctctcca atatatttaa caacatgttt
     6661 gaatctgcac cttgtttagt agagctacca acttcttcat tgtcaaatac agccattaca
     6721 tttacaccat gttgaccttt agtattaaca agagcattca aactagcatg taccattgca
     6781 agattatctt gtctcccaat agatataaat tcatcattag cccctattaa acttcctttt
     6841 tcaaattcat ataaaaataa atcaaaatct ataatatcgt ccatatttac atctaagtta
     6901 gatgctattt gctttataag aaaattatct ttttctaatg tatcatttaa catcccaact
     6961 aaaggtaaca tatctttttg cttattatat gagtgaccat catttatact tctatttaaa
     7021 tgtattgcta gatttggtat tatacaaatt ggctttttaa agtctataag cctttcattt
     7081 ggttttaata tactatcacc ttttaaaact actctaccag ctatcccaag aggtctatcc
     7141 aaccatgtac ttaatattgc tcctccatag cattctgtat ttaacttcaa ataagatttt
     7201 tcagcttcta tttctgcatt tggtttaata ctaaatgtag gagaatctga atgagagcct
     7261 attattctaa atccatctct ttctatacct tctgaattta ctacaaaagc tactatagct
     7321 gataaattct tagtaacata atactttcca ccaactctta gattccatct ttgattcaaa
     7381 actaattctt caaatccatt tttatctaag atttccttag tactctcgac tgcatgaaaa
     7441 gacgacggac tatcatatat gaagtctatt aagtttttag caaagtttat actatccatt
     7501 cctcatttac ctccattata aaatatttag tgttgtatat tctttattta tttttttaat
     7561 tccctgttgg tcaaaagcta tagtaacatc tgtaccaatt atagaaacca ctgtcccaac
     7621 cccaaattta ggatgatgta ccttagaacc aagttttata tcatctggat tagtttcttt
     7681 attagaatct tttattgtag cattaacttt atctgcaact ttagatttgc ttatagtact
     7741 catatacttt ttagtatatt tatctaacat attataactt gctttagaat agcttagttc
     7801 tttttttact ttgtacaatc tttctataca ttcttctggc agttcttcca taaatcttga
     7861 agctattgca acatttgttt taccatataa tgttctcttc tctgtcaatg acatatatag
     7921 ctcttcttta gctctagtta taccaacata acaaagtctt ctctcttctt ctatttgtga
     7981 atcactcata gattttatag ctcttgatat aggaaataac ccttcttcca tacctgttaa
     8041 aaacacaaca gggaactcta aacctttgga tgtatgaatt gtcataagcg aaaccctatc
     8101 attgtcttct tcatcatttg attcagatgt aagtgctata cttgttagga atgtctctaa
     8161 gtctttattt tcataagtat catcattact actttcaaac tccaaagcta tagaaataaa
     8221 ttctctcaaa ttatcaattc tgtcttgagc ttcttcacct ttgcctgtta aatctttttc
     8281 atttttattt cttatctcta caagctcgtc catatatcct gtagtatcca agactttttc
     8341 tataagtttg ctaacaggat aaacttcttt tatagttcta agagtcccta taatatcaac
     8401 aaatccactt atacttgccc ttgccttagt agatatatct gaatttgttt ctatatcaat
     8461 taatactgag tatatacttt cctgttttaa gttagctcta tcttcaattt tttctatagt
     8521 tctaagccct atacctcttc taggaacatt tataatcctt tttatagata tatcatcttg
     8581 tggattttga ataactctta aatacgccaa caaatccttt atttcttttc tctcatagaa
     8641 ttttgtacca ccatatatat tgtatggaat ttgacttcta tttaaagcgt cctctacagg
     8701 tcttgcctgt gcatttgctc tataaagtac tgcaaaatcc ttataaggtc tattttcttt
     8761 tctagctatt tgtgcaattg aatcagcaat gaaatcagcc tcttctattt cactaccagt
     8821 taattgtatc tttataagtt ctccttcttt tttttcactc caaagctttt ttctttttct
     8881 ttctatatta ttagatataa ctttattagc tgcatctaat ataacttgtg tagacctata
     8941 attttgttcc aactttacaa catgtacatt gtcataatct ttctcaaatt caagtatgtt
     9001 tcttatatct gcacctctcc atccataaat actttggtca tcatctccaa caacacaaat
     9061 attttgatgt tctcttgcta ataattttat caattcatat tgagctttac ttgtatcttg
     9121 gtactcatct accattatgt atctaaatct acttctgtaa tatgctaaca cttcatcatt
     9181 agccttgaaa agttctacag ttttaagtat taaatcatca aagtcaagtg cactatttct
     9241 ttttaaacgg tcttgatata gcgcataaat atctgcaatc ttaaccattc tattatctgc
     9301 catattgata tctttaaact gctttggagt ataaagtttg tcttttgctc ctgaaattgc
     9361 acttataact gcttttggtt caaacacttt atcacttaaa tttaattctt ttagacagtc
     9421 tttaaccaat gtaacttggt ctgctgaatc ataaattaca aaacttctat tgtaaccaat
     9481 cttatttata tcttttctta gtatacgaac acagcaagaa tggaatgtac ttatccacat
     9541 atccttagtt tcaggaccta tattttgttc aactctctct ctcatttcat ttgcagcttt
     9601 gtttgtaaat gttatagcta atatatttgg tgcttgtaca cctttatctt ctataagata
     9661 tgctattctt gttgttaata ccttagtttt acctgaacca gcaccagcca gtataagtac
     9721 tggaccttca gtcttttcta ctgcttctct ttgagcagga tttaatgtat ctaaattcat
     9781 atttctcctc ctgttaacag ccataaatat attttaatct aaaatatgaa ttacttcaaa
     9841 ttataattat gtattatatt aatagattat ttccaatata ttacaattaa ataacatttt
     9901 tccatataat ttatttcatt gtttaataaa aaaaataacc ttatgatttg gggaatcata
     9961 aggcaccttt aaggggtcta ggttaagggt tattatatat aaatctattt ttttaaaata
    10021 ggtttagggc ttaattattt atttgtatta agttctcttt ccttccaata cttatacaaa
    10081 tcttcttctt tcttaaataa gggtaaattc atatttctat gtacttttac taaccatggg
    10141 gattctaggc cagcttgtat aatattattt tcatttataa acacattttc tgcttttcct
    10201 tcatcaatca aaatcccctt atccaataca tatatgtaat cacatatttc atacattaaa
    10261 ttcatatcat gactggatat tactattttt atattatttt tatttaatcc ctttattata
    10321 tctacaatag acctagtact tactgggtct aaaccagctg taggttcatc aagtaataca
    10381 atttcatttt ccattgctat aactgatgct attgccactc tttttttctg tccatagcta
    10441 agaaaatgta ctggcctgtc tataaaatct attccattaa cagctactag agctttgttt
    10501 attctctctt taattgtttt ttcatccata ccaatgtttc tcattgcaaa ggctatatca
    10561 tcatatactt ttgaataaaa aatttgtttt tctgggtctt ggaagacaat acctacattt
    10621 tttctaaggt tgtataaact tctcttatca tattttaact tttcttcttt aaaaagaatt
    10681 tctccagatg taggctttaa tatacccatt aaattcataa ataatgttga ttttcctgaa
    10741 ccatttgaac ctattatacc tataacattt ccctttgaaa aatccatatt aatgtttaat
    10801 agtgcattgg tatttttttc atattgatac gttaaattat ttattttaaa catcattatc
    10861 ccctactatg tgaaatttac catcatacaa ttttatgtct aatgatatac acatatcatc
    10921 ataccttgtc ataagtcttt tgtacagcat acttccaaga atacctaagg atttatatga
    10981 agtttttaaa tttatatatc caaatcttag ctcttgtgac ttgtatattt ctgaaaattc
    11041 ttctaaaaat atgaatataa acctatatat taacattgat aactcgacaa aagtgtcagg
    11101 taaatgaagt tttttaaaaa agaatattaa ttgattaaaa ggtgttgtaa gtatacaaaa
    11161 atacacacaa gtcaaacaag acatcgctct aaataacaca tgaatagaca tgttaataga
    11221 cgcctttgat attcctacat taaaactaaa aaattcaaaa ctatataata aatctgcttt
    11281 attaaaagat atatttacaa gagttattcc tatactaaga aataaaaagt acattggtat
    11341 tctaagtaat tttaaataat tttttaaatc tattccagcc acacaaacaa ccaaaatact
    11401 cattaaaatc ataattccac ttaaaataaa tatattttgt attaccatag aagcaatcag
    11461 aaaaattact cctatggcta cttttttgtt tggatttact ttactcaatc tatttgtata
    11521 tgcatattta tcaattataa gcatgattaa cttctctttc ctttttgaag acctaatatg
    11581 tatcctatta caccagcccc taaagctgct tgtgcagaga ataataaact ttctatttct
    11641 ccacttggtg gctcatatgg actgctaaac catggtttgt aatttggatt tatcttagta
    11701 atttcacttt cagcttgacc atctgctcct ccatattcag cacctgagtt gacaagtaat
    11761 gggaatataa taagagctac tactaataaa agtaataata tgttagtttt tgtttttgtt
    11821 ttagcactca ttagctttaa ctcctttatc attattttct agtatgcttt tttctccgtt
    11881 ttctgtaatt aaattatata caattacagt aagtatacct tctgctattg ctattggtat
    11941 ttgagtcata aagaaaattc ctaaaaattt aattgctgaa gccattaccc cacctgatgg
    12001 gtctgggaaa gccagtgcta attgtattga agttattgta tatgtggcta agtctcctat
    12061 tgctgctgca agaaatactg gaatagcatt atttccatct tttttcttta aagccttaaa
    12121 tattaggaat gatacgattg gccctattat cgccattgaa aaagcattag ctcctaaagt
    12181 agttattcct ccatgtgcta ataacaatgc ttggaatatt aaaactatag ttccaagaac
    12241 aaacattacg cttggtccaa acattattgc tccaagacct acaccagtag gatgtgaaca
    12301 acttcctgtt actgaaggta tttttagtgc tgataataca aacacaaatg ctccacataa
    12361 agctaataat actttctttt tagggtcttg ctttactatt ttacctattg attttaatcc
    12421 gaataagaaa aatggtataa atataactcc ccatgctata gaccatttta ctggtaagta
    12481 accttccatt atatgcattg catttgatgt aactggagtt aaaatgatta acataagtgc
    12541 agctataacc cctaatttaa tattctgttt catcttagta tccctctctc cctttctaat
    12601 aattaaaaca taataataca tgtctgattt atttaataaa ataaaaaagc ctaactcgat
    12661 ggttaggctt ctaattttcc acaatctaaa tacaaacaca taaaacaaac atatctgtat
    12721 aattattata agaaactttc tccatccccg aagaaattac tttaatattt taggcaggtc
    12781 tcctgactta gcttcatcct actccttttc cttcccatga gatataaaaa atatcatcat
    12841 agtggctaac aaaagtttcg tctgcatcac agtagcgggg gctgtaaagg aatttaacct
    12901 ttttccctat taatcttgct taaagaacct ataatattat atatttaatt tttaaattat
    12961 tcttaaatca ttttctatat aaatcattgt ataccttttc tgtgaaaatt tctacatttt
    13021 ttataaattt tattcatttt tatattttta tgtatataaa ttcttttttg taagtttatt
    13081 aatttctaat tatcttcttt aaatacattg aaactacatc agaaaatcta gttatatctc
    13141 ttgaatatat aaaatcattt ccatatatta atctttcagc ttcaagttct gattcttttc
    13201 ctgtaaatac tcctaatact aatatatttt gctttctagc ttttctcact tcattggctg
    13261 tatctctcaa accaactata cccctataag ccttttctcc tcttaatgtt ctctcactac
    13321 tttttcctat ctttacatca tttggtcttc catcgctgag aactatcagg attttatttt
    13381 cttcatctct atttattaga ccactacata tagattttat tgccaaacca tctctattat
    13441 taccagcaca aaaatattca aatatatttt cactattttt tatactatca tcataatctt
    13501 taaatctttt taatattgta tagtctaaaa aactagaaaa tcccatcact ctatttggta
    13561 tgccaacttc tgttagagca tttgcaatta tgtaagcttg aattgccaca tttccctgat
    13621 ttctactttg agagccactt gcatccaata atatatcaat aacgtatttc cctttttcat
    13681 tttctatatc tttataaaat attttattat tattacttct accaactctc caagctctat
    13741 tggctaatat agtaccacaa tcagaatata ctctactttt agcattttct tctattaaaa
    13801 ttcttgacag actttctttt aatctcttta tttgctgtct atacattcta gcatgttctc
    13861 taaattttcc taaattattt tctttttgtc ttgttacata ttttagttga aatacattat
    13921 tacactcact tctaagaact ccatctgtaa agtgtattct acaaccttca tgaacatttc
    13981 tacaattttg tgtctcaatt tttttaattt cacctttact caaataagtt tttccataat
    14041 aatgttctat ttttgaatat atcttatttg cagtgtcttc atcaacatat ataactcggt
    14101 ctgctgaatt gctacattta gaatcatcaa aatcccctac accttctaca agcatggatg
    14161 aagatattga atctatatca ctttcaataa tattttcttc ttcatcacta taaagttctt
    14221 catacatgaa atcagcaaat gtatcaaaat ttacttctac actttctaca ttattttcat
    14281 caataagact attttcttct ccatttaata tgtattcaaa ataagttaaa tatataacat
    14341 ctaatgcttt taaaatctcc ataatatctt gattggtatc tatatttctt atatcattaa
    14401 ctattcttct agtcatacta tctaatgctg ggtgcttgtc catactataa agtacaaatg
    14461 tgtatttaat tttatccata atattatcat tgtgtatttt ggtaaaacgt gaaacaatat
    14521 ctttataagc attccttctt atgtcttcta tccctggcct gtctttaatg accttttctt
    14581 caactattgt atttaatata acttgaatta gacctagtat aacatctttg ttgtatcctt
    14641 ttcttattct atttgtaaga tattttttaa ctatatccca atctacatac tttcttctag
    14701 cacctgcaat tattgcgaaa tatagaccta tttcttttga agagtaatct ttttctgata
    14761 tatctatact ttcattgtaa tcaccagcta ttgtccatga taggttatta gctctatttt
    14821 caaattcata atcatcatat atccatttca taatctcacc tatattaaat atgacttatt
    14881 ggaaacacat ctatactctc ccatttatta ggtattctag ttttaattac atctccaacc
    14941 atttctttct catatacatc aaaagtcttt cctgtaagtc ccatattaat tgcaagagtt
    15001 ggttttaatc ctcttcttat agtcttaaga gatgccataa gaccacgtaa atcaatagct
    15061 ttactagata tctctccatt ttgagacttc aattgtaaat ctaaaaatat tcctgcaaag
    15121 tgtattaatt tttcttcatc agcatctgaa aattcatttt ttaaaatcat cattaactta
    15181 tcttcttcta taggaggaat atctattacc ataaatctag ataccagtgc ttcattaagt
    15241 tcttttgttc ctgcatattc ataattcata gtcccaataa atcttgttgc tggatgtaga
    15301 ttgactctct catacccagg tacatcaatt attcttctat agtctaaagc tgaatgtacc
    15361 acaactatag catcattttt tgccatatta atttcatcaa acaccccaaa acctccatta
    15421 atagcacact cataaactga gcctcttcta agtttaactt cattgtctat aaatgtatct
    15481 gtacctataa gtgttgaact gtctgtattt atatgaaatg atgtattcca ctgaggtcta
    15541 ttaaatattt cccctagatt atcagcaagt aagttttttc ctgttgcctt tggtcccgat
    15601 aataatatat tttcttcttc taaaatagct gctatacaca tagacaagat atctttacca
    15661 taaaaataag ttttagactt tgttactctg tattctaaat ctttttctaa accataataa
    15721 tttctaaaat acagtacatc ttcaataagt ttttcatcta ccccttgcac ccttagatta
    15781 tctattatat ccatattttt acccctttta tataaatagt atttgtttca tttcttatca
    15841 ccattttagc ataaaaggat ataagctaaa attgattttt taatctcccc attttaagta
    15901 aaaccatgca ccattttatc actacaaaat taagagtact acttactgat atttcttgat
    15961 tttgttcgtc tatacgtata taatatatgc tgataaatta tgaggaaagg atgattgaaa
    16021 tatggatgcc cagaagtagc aaaaaaatgg ggtatttctg aaagaagagt acaaaaacta
    16081 tgtgaagaaa gtcgcatacc aggagtttca aaactcgggt atatgtggct gataccaaag
    16141 aacgcagaaa agcctgttga tggtagaaca aaaagaagaa aggaagtaca atatgaatag
    16201 cgttttgatt atagatgatg acaaagaact ttgtgctctt atgaaaaaat gtgttgagca
    16261 agaaaattta tctgctatta ctgcacattg tggtgcagaa ggtctacatt tggtcgataa
    16321 aaatagacac acactctctc ttgtaatttt ggacataatg atgccagata tagacggttt
    16381 tcaagttctg aaaaaaatta gagaaacaag taatattcca gtaattatgc ttactgctaa
    16441 aaatgacgag gatgataaag tttccggact acgtttaggt gctgacgatt acctaacaaa
    16501 accgttcagc ataaacgaac ttatggctcg tgtcaattct cttattcgtc ggtatactat
    16561 gttaaaccct gcttttataa cagacacaga ttgcataata ataaatggca tgattattga
    16621 caagacaaac cgaattgttt ctgtcaataa tattcctgtt caacttacaa gcaaagaatt
    16681 tgatttactt gcttttctgg cttctaataa gggacgggtg tttaccaaaa aacagattta
    16741 tacacaagta tgggaagaag aatatgcttt tgacgatagt aacatcatgt ctttcatcag
    16801 taaattgaga aaaaagattg aaccagaccc caaccatcca ttttatattt tgacagttcg
    16861 tggtgtcggt tatcgtttta ataaggaggc ttaacatgaa tacaagtgtc tatctgcttt
    16921 tgatattggt tcttagcctg attattatag cgtaccttgt ttctgtcctg ctacgtgtcc
    16981 gaatacaact tacacttata aaagatgctt tagaggatat aaaaaatgga aaccttaatc
    17041 gacgtatttt aacagatgaa aacgacatta caaaacaaat ttgctatgat attaacgaaa
    17101 tagcaatcaa tagccaattt caacttattc agcaaaaaca atcagaacaa gcctacaaac
    17161 agctaatgac aagtctctcc catgatgtaa aaactccact tgcttctttg gtcggttatt
    17221 tggaagcagt agaaagtaaa attgttgtag gagaggaaaa agacgagtat atccatgttg
    17281 cgtctaataa ggctcattac ttaaagaatt ttgtagaaaa tctatttgaa tgggtaaaat
    17341 tggattctaa ggaacaagtt tttcattttg atatttttga cttgaatgaa ttatcccgta
    17401 atattatatc tgattggata cctgttttag aaagcagtca ttttgaatat gaatttgata
    17461 taccagaaat agagtacttc ttacgtatag acgcaaatgc atatacccgt atcattaata
    17521 acctattaca aaatattatt acccatagta gtggcaacaa aatgacattg agaatttttg
    17581 aaaacaaaga gcaagctcaa attataataa cagataatgg gaaaggtata tcttcagaca
    17641 atctcccaca tatttttgaa aggttgtacc aatgcgacca ttcacgagct tcaaagggaa
    17701 atggtttagg cttggcgatt gcaaaggaac ttattaacgc tcataaggga aatattaccg
    17761 ccaacagcac tcccggtatg ggaacagaat ttacaatatt gcttcctaaa gccctgtaaa
    17821 agtacgaggc tttcttactc taaaacaaga taaaagcaag attatggcaa ggttttggca
    17881 aggttcatgt tttataattc taattgtagt tgattttgac gttgtatcaa ctatcttttg
    17941 tagaaacaaa tttattaaaa gtgaggaaat tatatatgaa tgattttgtg attgaaacaa
    18001 agcaacttac aaaaatttat gggaatcaaa cagtagttga caaagtcaat ctccatgcaa
    18061 aaaaaggccg aatatatggt ctgttaggac gcaacggagc tgggaaaacc acaattatga
    18121 aaatgatttt aggattgact tcaatcacgt atggcgaggt agatgtattt ggagagaata
    18181 ttaagggacg tgaaaaacaa gtatatcccc gtatcggtgc aattatcgaa acgccaggat
    18241 tttatcctaa tctgacagga acggagaact tggagatttt tgcaaaactg cgtggtacag
    18301 ccgcccctaa ttctgtaaaa agagcattgg aaattgtagg cttaccttat aaaaataaaa
    18361 agctgtttag tgaatattca cttggcatga aacagcgact tggtattgcc aacgctatcc
    18421 tgcatgaccc agaactgtta gttttagatg agccaaccaa tggtcttgac cctattggta
    18481 ttgcggagat gagaaagttt attagggact tgagcgttga gcatggaaag acaattctta
    18541 tttccagtca tattctttca gaaatctcat tgttggctga tgatattgga attatcgacc
    18601 acggtgttct tttggaagaa agtagtatga gtgaactaga aaagaaaaac agtaaatata
    18661 tcctgctaca agtttcagat attccgaaga catcacttat tttagagcgt caatttaaca
    18721 cgaaggatta ttccgttcaa gatgactaca cgttacacct ttataacact aatctggata
    18781 tgggtgaaat caataaagca cttgtaatgc agaatgtaac tgttattagt tctcaacttt
    18841 gtaatgatac tttagaggac tactttaaaa aaatcacagg aggagagggc attgcttaaa
    18901 cttattcaaa cagaatttct taaactgcgt cgtaggaaac ttatttggct gatgttgttg
    18961 tctgctctca ttatgccgtt tttcgcacta ctatacttca attattttgg taaaacaggt
    19021 gttgagccaa taaagtttta taaatggtct gcatttggtt atacactttg gattattttg
    19081 cctgttgttt tgggtatatt ttgcaccatg cttatacacg aagaaaacca gtatgatatg
    19141 ctcaaacagc tttggattgt acctattagt aaaatgggat acttttttag taaatttttc
    19201 gttgttttga tttactctat ttgttttatg ctgattacag ccgttgcttc tgtgttattt
    19261 agtgtacttt ctggatatgt cgtatttagc tgggcaagca ttttatattt gttgaaaaaa
    19321 tgtttagaaa ttggtgtaat cactgctttt gtaatgttgc cgattttggc aatcgctaca
    19381 tctcaaaaag gatacattct cccaatttgt atcacattgg tatatgcctt ttccggtttt
    19441 gttataatga caataaatat gtatttacac ccattatcca gtatgggagt tattatcatg
    19501 agaaataaag acattccagg tcttatattt tcacaggaaa ttaatgtccc attagcattt
    19561 ctttgtattt gtatttggag tattgtatca gtattgtttg caaacactgc actaggaaga
    19621 agaaagtgag gtgtagataa tgtggaaatt actttgggct gaatgtcaaa aaattcgtcg
    19681 ttcaaaaatt gtttggatta cagtttttgc atccattatg atagcagtca tagtttttgc
    19741 aggagggcag gatgtatata atgacccaga tttacattat ggcttaaaga gcgtttatga
    19801 cggttcacgg tatatagaca atgcaggttg gtatatggac gcagtacaac cttggtcaac
    19861 tttttttgtt cttcctgctg tcattgccct attaggaagc tatattattt gtcgtgaaga
    19921 agaggaggac actattaaat ccctgcgtct tattcccata aatgaaacaa aattaaccat
    19981 agcaaaaatg attattactt ttatattcag tatacttctt tatttgttac tctttactat
    20041 aacatttttg actgaatccg ttttacattt ttccgattta tcgacaaaac tggttttaag
    20101 ttgcatgaaa gagtattttc ttgatggcat aggtgtattc tttgcaattt ctcccattat
    20161 tgccttggta tcgcgcatga aaaaaggata ttggcttgca ttagtattca cagaagttta
    20221 ttctattgct ggactatttg cgggtatgtc aaatgtctta caaacctttt ttcctattgc
    20281 ggcaatattt aatatttctg gatactatat aactactgga gaaaaaatta tggggagtat
    20341 cataagttta ttactttgtg cctgcctttc tgcatttata cttaaagggc taaaacacaa
    20401 tgaaaaaaat tgaaataggt atatcaaaat gaaaaagata aaaaaactga ttattctaat
    20461 tgtattcttg tttctttttg gcatgttaca ctgttatact gaatggaaat tcaacaataa
    20521 cccacctaaa ggggtaatag aaagaataaa tgaatggact gataagattg gactggatta
    20581 gtaacttatg ttaattatag tgaatgtaat attagcaagt tattgtttcg tattttaata
    20641 ctataacttt aaatatttgg ttttaatctt ccaaacgaat ataaaaaaac tgtcacagag
    20701 gcaacatatt tttgaatatt tataaagtgg tagttttgat tttcaaagct gccgcctttt
    20761 cttctatata agcaaactta tcctcaacaa agtgtaaaac atggtacatt ttaagaaaaa
    20821 agtaccacag acacaagcaa taaaagaaac gccgagaacc tacaaaaacg tagtgcttat
    20881 gcagatttac gacgccttct attttctcaa ccgtcttaat gaccttgtac aaaagaaatt
    20941 tttctaatat tttttataat cttatcttgt gatgtttttt atgtataaat gacttaataa
    21001 caaatccaat aaaaattatg gatattggta taattagaac gaggaattta taatcattat
    21061 aatgtgacat tattcttacc caactctcag aaaaaatata tcctatactg attaatgaag
    21121 tattccatat ggttattccc acgatagatg atattacaaa agttataata ttttgacctg
    21181 ctatacctgc tataaaagat atgtatgttc tacataaagg gattaatcta catacacaaa
    21241 cagaaataga agagtatttg ttaaaataat cttgagatgc aaatattcct ttctttgcct
    21301 ttggacatat ctctattatt ttatttatga tagatttacc tccccaattt cccactgtat
    21361 aacaaaatat cgaaccaagt atacctgcaa ttatacttaa aattaaaatt gtcagaaatc
    21421 caaaatgatt tcttgcagca attgctccac ataaaggtaa aacaacttcg ctaggtaatg
    21481 gaaaacaagc atactcaatc ataattaata caaatacaga gattaatcca tattgtaaaa
    21541 taaaactatt gattacagac acttacttat ctatctcctt tcttatttaa aggttttaag
    21601 ggtacatgtt ctaaggattc tcaccctata tttaaagaat caatctcttt aaactattat
    21661 atgtatttac acaaagcatt tataacatac tttaaaaata gtaccttaaa ataagaaact
    21721 taataaataa aaaaa
//
LOCUS       DAMJWC010000060        21467 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMJWC010000060 DAMJWC010000000
VERSION     DAMJWC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21467
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.060"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(41..919)
                     /locus_tag="PC503_002772"
     CDS             complement(41..919)
                     /locus_tag="PC503_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2528738.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(936..1253)
                     /gene="trxA"
                     /locus_tag="PC503_002773"
     CDS             complement(936..1253)
                     /gene="trxA"
                     /locus_tag="PC503_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2528739.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(1403..2635)
                     /locus_tag="PC503_002774"
     CDS             complement(1403..2635)
                     /locus_tag="PC503_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2528740.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(2625..3296)
                     /locus_tag="PC503_002775"
     CDS             complement(2625..3296)
                     /locus_tag="PC503_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528741.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(3312..4148)
                     /locus_tag="PC503_002776"
     CDS             complement(3312..4148)
                     /locus_tag="PC503_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528742.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(4174..4848)
                     /locus_tag="PC503_002777"
     CDS             complement(4174..4848)
                     /locus_tag="PC503_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2528743.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(4862..5590)
                     /locus_tag="PC503_002778"
     CDS             complement(4862..5590)
                     /locus_tag="PC503_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2528744.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(5717..6406)
                     /locus_tag="PC503_002779"
     CDS             complement(5717..6406)
                     /locus_tag="PC503_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2528745.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(6414..6977)
                     /locus_tag="PC503_002780"
     CDS             complement(6414..6977)
                     /locus_tag="PC503_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2528746.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(6979..7947)
                     /locus_tag="PC503_002781"
     CDS             complement(6979..7947)
                     /locus_tag="PC503_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF2528747.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(8048..8091)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            8457..9086
                     /locus_tag="PC503_002782"
     CDS             8457..9086
                     /locus_tag="PC503_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528748.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            9061..9465
                     /locus_tag="PC503_002783"
     CDS             9061..9465
                     /locus_tag="PC503_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF2528749.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            9468..9944
                     /locus_tag="PC503_002784"
     CDS             9468..9944
                     /locus_tag="PC503_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HDF2528750.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            10516..11181
                     /locus_tag="PC503_002785"
     CDS             10516..11181
                     /locus_tag="PC503_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF2528751.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLRQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            11203..12135
                     /locus_tag="PC503_002786"
     CDS             11203..12135
                     /locus_tag="PC503_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF2528752.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            12156..12797
                     /gene="pcp"
                     /locus_tag="PC503_002787"
     CDS             12156..12797
                     /gene="pcp"
                     /locus_tag="PC503_002787"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF2528753.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(12917..13249)
                     /locus_tag="PC503_002788"
     CDS             complement(12917..13249)
                     /locus_tag="PC503_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2528754.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            13515..14135
                     /locus_tag="PC503_002789"
     CDS             13515..14135
                     /locus_tag="PC503_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2528755.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(14460..15284)
                     /locus_tag="PC503_002790"
     CDS             complement(14460..15284)
                     /locus_tag="PC503_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF2528756.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNT
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(15295..16698)
                     /locus_tag="PC503_002791"
     CDS             complement(15295..16698)
                     /locus_tag="PC503_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2528757.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDDGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(16702..17427)
                     /locus_tag="PC503_002792"
     CDS             complement(16702..17427)
                     /locus_tag="PC503_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528758.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(17539..18312)
                     /locus_tag="PC503_002793"
     CDS             complement(17539..18312)
                     /locus_tag="PC503_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528759.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(18318..19205)
                     /locus_tag="PC503_002794"
     CDS             complement(18318..19205)
                     /locus_tag="PC503_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528760.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(19219..20241)
                     /locus_tag="PC503_002795"
     CDS             complement(19219..20241)
                     /locus_tag="PC503_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528761.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            20816..20992
                     /locus_tag="PC503_002796"
     CDS             20816..20992
                     /locus_tag="PC503_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528762.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         7455 a         3376 c         2307 g         8329 t
ORIGIN      
        1 ttttttataa atatctttaa aaagttaatc aatataaata ttaagccctc tttaatttat
       61 ctaaatagta aacagcattt aaagctgcta tttgcccttg accagctgct tttatataag
      121 aatagggttt tccaacacaa tctccagcag caaagcatcc atctatacta gtcttcatat
      181 tattgtcaac tttaatatga atgccatcaa tctctattcc aggaaccaat gcacttggag
      241 ccgtactatc ttttataacg aatactccat caacttcaat gtggttttct ttaaaagata
      301 ctttgtttac aagtttatct ccatctatct gtactggtct gtcatgtata acttcaatag
      361 aatcatctag gttatctgaa cttctcataa gattatcttt tttgtacata ggtataaaat
      421 aagtctttga agtgagttca cttaaaaaat ttgcttcttc tttagattct tcattatatc
      481 ctataactgc taccttttta tttctataaa gtggtgcatc acatgtagca cagtagccca
      541 cacctcttcc tagaaattct tcttcaccct tgattggtct agtatactct accccagttg
      601 caaggattac agtagtagct tcatacatat catttccaga cattattgta aagtattctc
      661 ccatagcata aatattattt attcttttat tttcaattga aatatccata ctatctatat
      721 gtgatttaaa cttgtctttt aattcatcac cacttatatc ataaaaacct aaataattat
      781 ctattgaagg agctttaaca agcttattac ttaaattatc attaccaaac atgataattg
      841 ttttatttct tatttttgca tttatagcag cagacaatcc agctggacca ctgccgatta
      901 tagctatatc atatctcata atactcaccc attttttata aatatgattt tacttgcatt
      961 tcaattttgt tctttggcat gaatccaatt aaagtttcta ctggttttcc atctttaaat
     1021 ataatcatag ttggtactgt agatacattg aattgttgag ctatttctaa actctcatct
     1081 atatcaactt ttacaaatct agctttatcc ttcatctctt cacctaattc tgcaaataca
     1141 ggtcccaaca tgttacaagg tccacaccaa gttgcaaaga aatcaactac aactactccc
     1201 ttactacctt caacactact tctaaattca gatgtattta taacttttgc catttttaaa
     1261 tcctcctatt aaactttatt atccctatat aattatacta tgaaatttat aaatataaat
     1321 ttacttttat aaggtctttt tatattttat actaattagt atacccattc ttcatttcta
     1381 aaaacaattt tttatatttt tattatttta acttttttgg tattgacaat tcaaatgtag
     1441 ttccaatatc tacatcagaa gttacattta tatcaataga taagtttaaa ctaatcatgc
     1501 gagctattga aagtcctatt ccagaacctt ctaaatcttt atttcttaca ttttcacttc
     1561 taaaaaatct atcaaatata agaggtatct cttctttttt tatgcctata ccagtatcac
     1621 ttataagtaa agttacctca tcctctatat cttctttcaa ttctaatgct atctcatcac
     1681 ccaattttgt atacttaaag gcattatcaa tgaaaattaa tataagttgt cttaatttat
     1741 ttttatctgt tattataact ttattcttca gtttagaatt aaacacgaat cttttttcct
     1801 gaaactcagc aatgtcaata tagtcttctg atatttcttc caataacttt tctaaatcta
     1861 tttcttctaa attaacttta acaatagagt cctctttagt aagagacaat aaatcagtta
     1921 tcattttttt aagtcttcta gtttccttca ttgcagtagc tattgtttca acttcatcat
     1981 ttactgtact ttctggggat tttaacatac tttctaattt tgatgaaact attgttattg
     2041 gtgttcttaa ttcatgagaa gcatcttgta taaacttagc ttgatttttc catgctgttt
     2101 ctattggaat taaagctttt ctagtgagat atacagccac aaagtaagta attattacag
     2161 aaattaatat tccaattata agaacagatg taagctgtct taaagaattc atctcagaat
     2221 ctatatttct aattatctgt atttggtatc tacctacatc tacatttaat tctctaaaag
     2281 tatatccatt ttctgtgtat ttaaaaaacg aatttttttt atctagtctt ctatctggaa
     2341 gtaactcatc aaaatattca ttttgagtat agtaacttat ccttccatct tcatatacat
     2401 acaccatatc tttaggatct ttgagtctta ttgggttcaa aaatgaagtt cttttaaatt
     2461 gagagactat atattcaagt tcatcattta tctcactatc aattccacta tatgtaagtc
     2521 ccctaaaata tgagtatata aatatagaaa agattattaa aaaactacct actacaataa
     2581 tatacatttt tattaaatga tttttagtac tggtaaatac attcttattt atcatcgaat
     2641 atatatccta ccttacgttt agttttaata tatttatcat atccatattt acttagcttt
     2701 tttcttagat tacttacata tacttccact atttcaatag ttgcatctga atcaattccc
     2761 catattctat cataaatctg ctcttttaat aaaattgaac ctttatttaa tacaaaatac
     2821 tcaagcaagt taaactgttt gttttgaagt tttatttctt ctttttcaat atacactctt
     2881 ttttctagtg tatctaaata taaagattta aattctaatc cgtttctttc ttttatcttt
     2941 ccattagtcc ttaatatagc gtatacccta gctactaact cttccatata aaaaggtttt
     3001 gtcaaataat cattagctcc tatagtaaat gcttctactt tgtcatctaa tgtttctttt
     3061 gctgtcaata taagtacagg tgtatctata ttattaattc tcattttctt taggatatca
     3121 aatccattta tattaggaag cattaagtct aaaatgacta aatcatatat attttgattt
     3181 attaagtata aagcttcttc tccatcttca cacttttcag tttcaaaatg cttgctaagt
     3241 tcttctacta cactttctaa aagtatctta ttatcttcaa ctattaaaac cttcataagt
     3301 atcccctacc tttatttgtc tatcttaact ttatgagatt ttaagtcaat atccacattg
     3361 gctttttctt ttatatcatc atacgtatat cccactattt caacactttt tgcctttgtt
     3421 gaacacaata tatctatatc tgtctcttct gaaggcttta aaatcttata tgatggtaca
     3481 cgatttactg ttaaatattc tccattttca ttaacttctg ctgtcttaag aataatattt
     3541 cctaaatctt ttgatgatga attttttact tttacttgat acgtaattcc ctcatttgat
     3601 tcatttactt ttttaagttc tgatgtagat agcacctcat actgactact attttctagc
     3661 ttaatattat tatttcttat attaatagta ttttctttta aattaacata cacaatctta
     3721 ccctctgcct catattcata tgcataaact tctacaccct ttacaaaagt tttatgccca
     3781 cattctatgt aagcaacttt cccaggcatt aaagtcatgt ccaacaaagc cttactatcc
     3841 gaagatataa tttttttatt ctcatcatat tcattatata tcaattcaac attggatata
     3901 ttaaatgttg aattattttc tacctttgtt gatgtatcta ctttatcacc ttcatctata
     3961 tttataattt ctgattttcc tatattcaat acttttgcat ttccctcatc tatttttatc
     4021 tcatttttat cttctgtttg aatatcaact gaatcaggct gttcatcttt ttcacatgct
     4081 gtcaacataa aaataaatat tgttaatata atcattagag aaattgattt ttttactatt
     4141 ttattcatat taagcacctc atatagtagt attttatagt agatttttat actttttcat
     4201 aaattctttc aatgcctgtg taagtatttg atgtttttca aaattcgaat tactacataa
     4261 tctttcaaaa tcattccata tttctttatc tatacgtatt cttgttgttt ttaattcatc
     4321 tatgtgttca tcatctatat gtacatcttt tttattagat acttttttag gctttatatt
     4381 gtaatctttt acttctaaat accaatcata tacttcacaa agcttatcta aatcttcttg
     4441 agttatattt atttttctat ctttcttagg cttaatattt tgttttggct ttgcattttt
     4501 taaacctgta tcattaaact caatttgttc aacactttta cttaaagcct tttcattaga
     4561 aatctttttt ttggtgctta ctttttttct attacttata gtattctttt tacttttttc
     4621 atactcctta gctttctctt cttccaagtt tctattatcc aaacttttat tataatttaa
     4681 ttcgtctttt aatatgtatt tacctttttc tgacttatat ccttttttat ttaaaaaagt
     4741 tcttaaagta ctttgactaa tctttagatt ttgagctatc tctgcaaatt taaatccttt
     4801 gctttgaagt tctaaaaatt tgtcaattct gtcttcattg ttattcatta atattcctcc
     4861 gtcaacatct tcttgtcttt cttttcatac ttcttattat attcttcttt tctaaatcta
     4921 ctctatttga ttcaattatt ttttgtagca ttttattata agtgaaatca tctaaattat
     4981 tattttttat atagagaaaa gtttcctctt cacatttaat aaaacaaatt gatagcaacc
     5041 atgccatacc cattttaaca taatattctt cactttgtat attattacag tattcaaata
     5101 tttctttaat atgtttatca tcaacataat atattaaaaa cataactaat gcaaatctaa
     5161 tttcccatgg attctttgaa taaacatatt ttttaagtat atcatacata ttttctttat
     5221 attttttcat agactttaaa tcagaacaaa atccatcgca aactgaccaa ttatcgattt
     5281 taggtataaa tctttttaca tagtataaag tttcttcaaa attactattt atattgccaa
     5341 ttaccatacc ttgtagccta acttcttcat agtatgtatc ctgtgctact tctaaaaatt
     5401 ccttccaatt cccttggctt atttcttttg ataactttct taaattagga actctaatac
     5461 ctattatatt ttctgttcca ggtataagct ttttattaaa atctctatat tttatatctt
     5521 gtatagacat catatattct aaaagttcat tataatccaa tttattccat tttcccctat
     5581 caaacatcat ttaattgctc cttaattcct tttttcttat tgtaacataa aactctacaa
     5641 aaaaagcttc taactattag aagctttttc aaaaacataa gaaacttttc aattttaaat
     5701 ttaaactaaa ttaatgctaa tctcctacac caaagtctgt attattgtat aaaacttcta
     5761 tatttggatt ttcatccaag aatttatact tactaacaaa ccatttcact aactcttcat
     5821 ctctttttat actagaagaa ttatttataa aaacattcac tgtcgctttt tcaaaagtat
     5881 ttaggataat ctctatatct ttatctatca tctcttttgt ttgtcctttt attccaacca
     5941 taatacaagg tgaatcaaaa tattctttta catcttgtgg agtcttaaaa tttgcatttt
     6001 tatttaaaat attatttcta aaatcattgt caaaggtttc aactccaatt ttaaatacca
     6061 caggaatttc aaaatactct ctcatttcct taagcctatt tttgtaagac caatgacttt
     6121 ctaaaaataa tttttttata ttcttctctt ttataataca ctttattttt tctaaagtat
     6181 ccttaggtaa ttcaaaacag cttccagaat ttatgacttc aagaactcca tatttcccag
     6241 ttacgttttt taaaaccttt agatttaatt tattcatctc ttcttctaaa ttagaattat
     6301 catctatata atcacaaaaa gaacactttc cccatataca aggaaatcct ttaagcagaa
     6361 caatttctct ttgattttta tttgttatct cactatatct atccattttc tatctatttt
     6421 cctccagtca atgatacctt taaagttttt ggaactgcat ttaatcctaa attcactaaa
     6481 acaactgcta acagcttatc tccataatca gtaaatactt gggttacaaa cacactaaaa
     6541 acatccccca gtcctaacac tttcaagatt tgcactatat atgatgaacc tgaagaggtc
     6601 atacctccaa ataaaaatgc tgaaattatt gaacttatta tagatgttgg aatggcaaat
     6661 aaaagtactc ctagtggagt ttttaaaccc cttaaaaaat tctttttaaa tgctattcca
     6721 gcaagtaatc cggttgatat ttgaactggt gcaaaataga gagaatacac atcaaacgta
     6781 attccactta ttaaacttcc aaacacacct gtaacaacag cgtatttagg tcctaaaagt
     6841 gaagctatca ttatagttcc tattgaatct aagtatacag gtaatcttaa tcccatagct
     6901 ataaaagcgc ctattatatt tatagaaata ccaaaagcta taagtgtaat agtttttaca
     6961 catatttttc ttttcacact atatcactcc ttccacagag tctataatgt cttcataacc
     7021 tttaaaaagc ctctttaaaa acatgtacat aaatttcttc tcatcaactt catttagaac
     7081 aattgcatta ggattttttt tatagaaatt gaaagaatcc actatagact gacccatagc
     7141 tattccatct tctacaactt ctacatatga ttcaaatcct ttacatatac ttctatctat
     7201 aaagtatgct actgctagag ggtcatttat cacacagcca attattccct cctgttccca
     7261 atggaaatca atataaaatc tagttatttc agttatatac tttgccatct tcttatcaag
     7321 tctatttata aactcaataa tattaggagt aagtacaatt tttctagtta catctaaacc
     7381 taccatgtgg atttttttag ataaattctt gtaaacataa tctgctccat gtgggtctac
     7441 ccaataatta aactctgcta ctggagagca atttccatga atcctaaatg ctcctcccat
     7501 agatacaaac tcatcgagat tttcaaatgc tttcttatct ttaataagtg ctttagctat
     7561 atttgtaagt ggtgcaagtg ctattattga tactttttca tgattatata aagtatttat
     7621 tataaaatcc actgctccat tttttgcttt agctcctaca accttttgat aaaagttttc
     7681 tccaatacca tcttctccat gtgtatcttg agctgttaca agttttcttt ttagtggtgc
     7741 ttcttctcct atatatactg gaatatttag tgaagaacac atttgaagtg tttttagtgc
     7801 attttctgca cctatatttg ctgggacatt tccacaacat gtggtaattc caattacttc
     7861 tagctctggt gagtttaaag ccagaagaat tgccaaagaa tcatcaattc ctgggtcaca
     7921 atcaattatt acttttctct tttccatttt ttatcctcct tgatttgtgg tcgaggagaa
     7981 ctacacatct tttttccact ttcaaaaagg tgtgtctaag ggtattaatt atatactgcc
     8041 actatataat tccttagttt tttatacttg gagttctcga acaagtacag atgtaaaatc
     8101 atatttttag gctacttact ataagactct taaaaactat agaccgttaa aaaattttta
     8161 aacatctgat ttaatagcta taaaataaat tttatagcat aaaagaattt attatatttt
     8221 aatgtatctt attaaagttt atttagaatt atgaaccaac tttaataaga tgtggcgcat
     8281 ttaaaccgat tattattata caataatatc ttaaatatta caattaataa cattaattta
     8341 ttatccataa aaatatatta acttatatta tttaataatt tattgacagt attaaaatta
     8401 aattatacaa taacagtgta aattaactta acaccgttaa gcaaagaggt gattatatga
     8461 gtatcaaaga aagacgtaaa aatgaaaaag aagaaatgaa gaaaaagatt atggatgcta
     8521 gcatcgaaat tataaaccaa catggatatg aaaatttatc aataagaaaa attgctacaa
     8581 aaatagaata ttctccaact acaatttatc tttactacaa agacaaagca gagattatca
     8641 gcgatatgac caataaactt tataacacag tagaaagtaa tgccattgac attatgaata
     8701 attgctcatc actaccaata gataaacaaa tcatagaaat tatgactagc tttataaaaa
     8761 ctctttctag tgaaccagag atggcaaaat ctatcatgca tagtagaatg aatattatat
     8821 ttgcatctga aaatacaaac aatacgccta gcaataatgg tataaaaatg cttgataaat
     8881 tcctttccat tggaattgaa caaggaatat tcaaaaaaaa tatagataaa agctcatgga
     8941 tgcttataag tgcattgtta ggattcgttt tatgtgttgt tgaaaataaa ctatattctt
     9001 tacataattt ttctcaactt atagaaaatt tcttagatat tttagtggga ggactttaca
     9061 atgaaaattc gcaacaaggc tactaataaa aagaaaaaat atgtaaaaat atctattgct
     9121 ctattctttg tatttatatg cattattatt gtaattgtaa gcaacttaaa gccagaaaac
     9181 ttggtagtaa aagatataga tattaataat gttaaaaatg gcatttatac tggaagtgct
     9241 gataataact tggtaaaagc tactgtgtct gttgaagtta ataatggtaa aatccaaaat
     9301 attaatatct taaaacacga ccatctttta ggtaaacctg ctgaaaaaat tacaacaagt
     9361 attattaaac aacagtcttt agatgtggat gctataactt ctgcaactta tagcagtaat
     9421 actatacgaa aagctgtaga aaatgcttta agaaagggag aataattatg aatactatta
     9481 ttatatattc aagtaaatat ggttgtacaa aagactgtgc aaatatacta aaaaataaac
     9541 tatcagataa tgtcactatt gttgatatta ataataataa taataaaatt gagttatcaa
     9601 aatttgataa aattattatt ggaagttcta tatatgttgg ttcagtttca aaaaaaatac
     9661 aggtgctatg taatgataat gtagagttat taaacaaaaa acaagttggc attttccttt
     9721 gctgtggctt ttctgaacaa gcagataaat atttaaaatc aaattttcca tcatccttat
     9781 tagaaagtgc aaatgctatt ggaatttttg gtagtgaagc tcgattagaa aaaatgaaat
     9841 ttttagataa acttattatg aaggctgttt caaaaggtaa ttatgacagt tttagaatat
     9901 cacaggataa tatagataat tttttaataa atcttaatag ctaaaataaa gctaattatt
     9961 tctatgataa attcttttat ttataagtaa tattgctcaa aatagtcttt aaactttatc
    10021 aaaattttat ttttcttagt gaaatctaat gaaactagca cttaatatat gctttattaa
    10081 tcataacaaa tatgttttat taatcataac aaaaagagag tgtctaatga actaaaaaat
    10141 tcattagaca ctctcttttt gtatgaaatc aaatatattt ttatcatttc aacagagaaa
    10201 aatacacttg tctctatgtt tggcacattc tctttttata atataatgtt taatttaaaa
    10261 ctactatttc aaatattgac atatacttaa actatagact tacaaaatca attcatatta
    10321 gcttaaaata taatctttgt tattcaaatt cctatacaca accattattt actttgatac
    10381 tttaaaacat cttccctatt ttttattaaa ttttataata atagtcctat taacgcaaat
    10441 actataaaaa gagtttaact ttatccatta aataaattta aattaaaaca tatagaaatg
    10501 gaaggagaac aatttatgat aaaactaatc ggtatattga tagttgtaat tggatttata
    10561 cttaaaattg acacactatt tactgtatta ttagcaggag tggcaacagg aattgttgca
    10621 ggattagatt ttaatcaaat ttttacaatt ttaggagatt cttttgtctc aaacagaggt
    10681 gtatcattat tcatattaac attgccagta atcggtgtat tagaaagata tggtttaaga
    10741 caaagagctg tttctttaat agaaaaatta aaaagactta caacaggaaa agtacttact
    10801 atatacatga tagctagaca aatagctggt gctctatcaa taagaatgag tggacatcct
    10861 caatttgtaa gaccacttgt taatcctatg gcacaagctg ctggtttaag taatagtgat
    10921 gaactaaaag aatcggatga agaagccata aaggcattat ctgctgcatc agaaaactat
    10981 ggaaattttt atggtcaaaa cttatttgca ggtagtagtg gagtattact tatagcatct
    11041 actctgactc aatttggata caatgtaact ggacttaata tcgtaaaggc tagtactatt
    11101 atggcagtaa tagcacttgt agtggctaca atccagttta ccttatatga taaaaaatta
    11161 aacaaaagtc ataaaaaata gttttattta ggaggaataa aaatgcaaaa ttttataaac
    11221 atatcattgg aaatctttta cgcactaatg ggatttttaa tgattgttat agcatataag
    11281 tcttttacta ccataaataa caataagaaa tatggtacat cattattttg gatacttata
    11341 tcactgccat tcatatttgg tagattgatt ccagccaata taataggaat aatattaata
    11401 ttatctagtt tattaacact ttctaaacaa gttgtatttg caaagtatga agaaccagat
    11461 gaaaattttg gaaaagaaca agcagacaaa cttaaaaata aaatatttat accatcatta
    11521 atattagcat ttgctgcagt agtagtagct atgagtcttt ctaattttga taattcttct
    11581 cagtttgcaa taggtgtggg ttcaataatt gcattaatat cagcccttat aataactaag
    11641 gcaaaacctg ctacatcagt tcaagatggc tcaagattac ttcaacaaat gggacctgct
    11701 agtatgttac cacaactttt agttgcattg ggagctttat ttactcaagc cggagtcggt
    11761 gaagttattt caaccatgat atctggtgta gtccctgctg atagcagatt atttggtgtt
    11821 atagcttatg tattaggtat ggttatattt accatgataa tgggaaatgc atttgccgca
    11881 ttttcagtca taacggcagg aattggtatt ccttttgtat tgtctcaagg tggaaatcct
    11941 gctataattg gagcattagc attaacagca ggatattgtg gaactctact tactccaatg
    12001 gctgctaatt ttaatatagt tccagcagcc ttgctagaat gtaaaaatga ttatattgtt
    12061 ataaaatatc aagctccagt tgctttggta ttaattatag cccacatatt agtaatgtac
    12121 tttttaggat tttaatataa ttaggaggta aaataatgaa aattttgtta acaggatttg
    12181 acccatttgg cggagaacca ataaacccag ctcaagaagc agttgaaagg gtcaataata
    12241 atataaacgg tgcagaaatc ataaagataa ctataccaac agttatgaca aaatctgttg
    12301 aagctataga taaagctatt caagagcaca atccagatat agtaatatca gttggacaag
    12361 ctggaggtag atttgacatt acacctgaga gagttgctat aaatatagat gattttagaa
    12421 taaaagataa tgagggtaac caggttatag atactattat aaaagaagat ggtgaacctg
    12481 catatttttc aaaattgcct gtaaaagcta tggtaaaaca tatgaatgaa aataaaattc
    12541 cagctagtgt ttcaaacact gcaggaacat ttgtttgcaa tcatgtgatg tatggaattc
    12601 tttatatgat agacaagaaa tatcctaata taaggggtgg atttatacac atcccatata
    12661 caacttcaca agtaatagat aaaaaaaata caccattcat gtctttagaa gaaatagtaa
    12721 aaggcttaga attagctata gaagcttgta ttatatataa agaagatgta aaagaaattg
    12781 gtggtgaaat ttcataataa attttttagt atttttataa attaaaaata ctaactatta
    12841 atttaaatat agactgtgag tagattattc aaacaatttt actcacagtc tttttatggt
    12901 atctacagat acaaaattaa ggtctattcc tctctcccca ctcacacatt gcatctaaaa
    12961 ttggaatcag agattttccc ctttctgata gactatattc taccttagga ggtatttgag
    13021 gatattcagt acgaataatc aagttatctg cttctaattc ttttaatgat aaactcaaag
    13081 ttttatagga gatagtattt atataacgtt ttaatgcatt atatcttaca acttcaaatt
    13141 ctacaagaca gtaaagaatt atcatcttat atttaccact aatcagtgaa agtgtataac
    13201 taaatcctgt ttcacttaaa tctgtatttg atatacagtc tatactcata tattacactc
    13261 tccttttggt tagtattgaa caaaaatgtg cgtacttgtt tttagaataa tttataataa
    13321 aattatagtg taagaataat tgaaagtcaa ttttataata ggaggtgtat ttactaaaaa
    13381 aaaagttatt ttaaatagga ttctaagatt agacatttct atataaattg ataatattca
    13441 tgaaaatcct attttataaa aaataatgtc tcttagaaaa tctattaaat aaaattcatt
    13501 ggaggaaatt tataatgaaa gttttattga taaacggtag cccaaaccaa tatggatgta
    13561 cttatacagc actaaatgag attactaaag tattgagtaa acacgatatt aaaacagaaa
    13621 tactgtattt aggtaaagaa acaatcccag gatgtattag ttgcgcatcc tgttttgaaa
    13681 ctggaaaatg tattcgaaat gataaagtta atgaattgat tgaagatctg gataatattg
    13741 atggtattat tattggttct cctgtttact tttctagtgc aactggtcaa ttaacttctt
    13801 ttcttgaccg tctatttttc atagctggga gtcgcatggc tacaaaatta ggtgcttcag
    13861 ttgtgtcatg tagacgtggt ggtgcaagtg caacatttga ccaactaaat aaatattttt
    13921 caatcagcaa tatgcctatt gtatcatcac agtattggaa ccaggtacat ggctttactc
    13981 cagaggatgt tatgaaggat gaagaaggat tacagactat gcgaactcta ggagaaaaca
    14041 tggcatggct tcttaagtgt atatcagcag gtaaaaaagc tggaattaaa gaaccacaat
    14101 atgaagaaac aattatgact aattttataa aataaataaa aaatgtacta atattaatta
    14161 aaacaaaaca ctaatttata aataaaataa gcataaatgt aggataaaaa gcactaaaac
    14221 agaggtattg aattttatat caaacctctg ttttattatt acattaataa ccaaaccatg
    14281 tataacatca tatatttcta aataaattat aatattatat tctaatgtta ttgaaattac
    14341 aataactgaa tttctgctca taaatttaaa tattctacaa atctcatcta aataacaatt
    14401 ttaatagacc taaaacaatc ctcatactgt tcattttgta ttaaaaatat cacttacaat
    14461 caaaaaccat ttattaagta tattcctaag atatacaata tatatacatg gattggatag
    14521 tataaataaa ataaatactt catactcttc cctttttctc cattgtaaag taacattaaa
    14581 ggtagagaag caatcatcat ccattggtaa ttttgtaaaa tagaattttt taaactataa
    14641 tctccatttg acattgttgt aaatataaat atacacatta aaacataaca aatactcaaa
    14701 ctgaactttt tacctctaca caaataaaaa ataatcccaa gtataatcca aattggtcca
    14761 ccttctacta aaaatggtac tggtaccaaa atcataaata aagcaataac tctgttagtg
    14821 actttaaaaa gtaaagctac tgtaaatatt cctaaaatta taggaatgat tatcatcaat
    14881 aatcctataa taaaatattt aatttctttc tcttttctaa atttctttat gaactctatt
    14941 gcttgtaaat aaatcgctat taaaaataat gttgaaaaag tgttatttat aattatagct
    15001 ccttctggat gtgaaaatac attattaatt atttgatttc ctatagccat aataacagac
    15061 caaatataca atctacttat atattttttt ctgttactag tgtgataaaa tccttcaaca
    15121 gccatgaata taaacagtgg tgctgatatt ctgcctaccc aatgaaacca aattggtatt
    15181 tgcattgttt gtggcataaa tgctgctata tggtcaaatg tcataaatat taatgctaaa
    15241 atcttaatag taaacccact tatacctttt ttaaaaaaat ccatatcata tctcctaatt
    15301 ttgttttatc tctataataa tttttgttcc tattccaatt tcactactta cataaatttt
    15361 acctttatga atctctatta tttctttaga aatagccata ccaagacctg aacctttatg
    15421 catctcacct gtattagtac ctctataata ttttttaaaa atatgtttca aatcactttt
    15481 gcttattcca attccatcat cttttattat aatttctata ttatcttttt ttacaatttc
    15541 tacacttatc aaagttcctt cgctattatg aactattgaa ttaaatataa gattggttat
    15601 agcccttctg aataagattg aatctacata tacttcaatt aaatcttcat tactttcaaa
    15661 ttcaatattc ctatttttat atctattatc atttaaaata tcaattatta tatctctgac
    15721 taaactgact aaatttattt ttttcttgtc cagaactata gtattatttt ttaatcgagt
    15781 agataaattt aaatcatcaa ctaaatcttt tatatactta gacttattat atataatttc
    15841 tgtatactct tgtatttcat cttcttcaaa ctcataatct ttgtcattaa ttatctctgc
    15901 atacccttgt atagatgcta gaggtgtctt tatatcatgt gttatatttg ccaaccattc
    15961 ctctctcaac tcttcatttt cttttctctc aacttcattt actcttaaag tatcagctaa
    16021 catatttata tttttaaaaa cttcttcata tatacctctg tccttaagat ataaactata
    16081 atttccatta gccatagtct caatactcca tagtacgctt gaaattggtt ttgtaagttt
    16141 tctactaaat aaatatccta cacctaaagc taccacgcta tcaattacta gtgttataat
    16201 gataacttta tttaaagttt ttttaatgtt attttgagaa taggttaaaa ttattcttga
    16261 tatatctcta ctaggtatac ctactattat gtttagatgt tttttgttta aatatttttc
    16321 taatacaaaa ttaacatact ttgtttctat atacttgtaa ttattcacca tttgaaaggg
    16381 tgtatatttt ttgggagtat cctttggcac atttactcca taaacttcct ctcctaaatc
    16441 atttaaaacc tgtatccagg aatttgattt ttctaatttt tcagctccaa tcttagatag
    16501 tttaaattct ccatcttttt catataaatc tttttcaaaa gaacgtgcaa attcttcagg
    16561 attatttcca gaatctacaa ctttaaaaaa actattagtt gaaatcacat acaatataga
    16621 tatgatattt ataattacta ctgatatagc tacaaacaca attgtaaata taaaatttct
    16681 agtaatcttc cacttcatat tctaatcttc ctttactgct aatttatatc caagaccttt
    16741 tattgtcaga atatattcag gctttgaagg attatcctct aatttttccc taatttttct
    16801 tatatgaacc attatagtat tgtcaaatcc aacataatct tctccccaca ctttatccca
    16861 tagtttttct ttacttataa tttgattttg attatgtgca aataaagata ggatttttag
    16921 ttcctttgca gacagtccta tagattttcc atcttttata agttctgccc tactttcatt
    16981 taatatatat gggccaaatg atataatttt ttcttcatta ttatttagat ttttactttc
    17041 gttttgagca tcactaaaat aacttaatct tctcaaatgc gctttaactc taaaagccac
    17101 ttccttaggg ctaaaaggtt ttgtaacata atcatctcct ccaatcgcta gtccaagtaa
    17161 cttatctaat tcttcggttt tagctgataa aaatattatt ggagaattgg aggtttttct
    17221 tatttcttta caaatatcat aaccttcgcc atctggtaac ataatatcca atacaatcaa
    17281 atcaggatta atacttttaa ataattctaa tccttctttt ttagtttttg cagtatatat
    17341 attattaagg ccctcttttt ttaggacagt ttctaaaagc ttcaatattt ctacttcatc
    17401 atctattatt aaaacacgat tttccataaa caacctcctg taataattta catatatatt
    17461 agcatatatt ttatctaaaa ttcatttatc ttatttttaa ttaaactaaa atataaataa
    17521 aattactatt atttttagtt aaaacctttt gcttgatgta aaattttcat atgttatttt
    17581 agttaacact atcattaata taattgagat tactatagaa aaaactatca aaatacttgg
    17641 tacattatac ttaaccattt gttggctcat cataatccaa tttggagtca ctgacataaa
    17701 ttttatagct ttatctggta taaaacctac actaaagtat ggaattgcca ttatcaatcc
    17761 acctagtata aatggaatta cagccgattt aaatatagat gaaagtgtta agcctatttg
    17821 tgcaaatata aaagaagcaa aaatagtagt caatataaca attatataca tttgtattac
    17881 tgtaagattt aaattactat ttccaaagta ccataagtta tgaatcgatt catttaaatt
    17941 tttaaaatca aaaaaactaa aacctctaat tcctactaac aatataaaag aaatattaat
    18001 aatagataaa attaatccat tagctactag ttttgataat actactgatt tttttccctt
    18061 tttagttgta tttattaaac ctgtcatatt agaatcatat tctttaatgt aatttccaga
    18121 agttattata aacattatca aacctattag aggtattgag ccttctatct tgtaaaatat
    18181 atctgcataa gtatctaaaa catcaaactt tctaatcaga aaaaatccaa aaaatattaa
    18241 aaacagccaa attatccaaa cactctttga ttttaatatt tttatcattt cagctttaac
    18301 taaatacatc atttctacta cacctccctt gcatcttcta aatcaaaata aaacatgtat
    18361 acatcttcga attttgcttg aactggttgt atattatcct cgcttggaat atcctctgaa
    18421 acaattctaa gtactactga atcaatatca ctttgaatac ttacaacctt atatttagat
    18481 tgtatatcat caacttcaca ttcattttta acttgaacat tatatacttt attttccatg
    18541 tgacttaata tgtctttgtg tgttcctttc attaggagtt tgccatcttt aatcattatt
    18601 gtttcctttg caactgattc tatatcggaa attatatgag tagaaagtat tattatctta
    18661 tctctagaca tttttgctat taaattccta aatctagctc tttcttgtgg gtcaagtcct
    18721 gctgttggct catcaaggac tattatctta gggtcgttta gtaaaacttg tgctatccca
    18781 actctcctct tcatacctcc tgaaaatttt cctatagact tatttctcac atcataaaga
    18841 cctactaaat ctaataattc tcctatctta ctatttaaat attttcccct taaacctttt
    18901 aaagctccaa tatactgtaa aaattctttt gctgtaaaat ttttataaac tccaaattct
    18961 tgtggcaaat atcctaaaat atttctataa tcagcatcca ttttaaatat atcctcacca
    19021 ttataaagta tctgaccttc atcaggtttt atcaacgttg ttatttgttt cattaatgta
    19081 gattttcctg ctccatttgg tcctagaaga ccataaactc cattttccag agttactgta
    19141 atcttgtcgt ttgctacttt tttaccatat atctttgaaa gattttctat ttctaattta
    19201 ttcatcttaa ctcccctttt atctacttat ataatctgat tttattacta aaaaacataa
    19261 tgacatagca cctatcaata ttgccatcaa aagtcctatt gctatattga caatgtctat
    19321 attcacttta aatatcataa tatcacctag ataatttcct attattttat taaaaccaaa
    19381 tatcaaatca taataattta catttgatac aactgaaagt aattttttag gtaatatatg
    19441 gattaccgac attatcttag ttatagatat aataaatata aaaaaactta ttgaagatat
    19501 tgaagactta cttataaaag acccaaatat ggctatcatg gcccatcctt caaacatcaa
    19561 aagctctatg cctatattta atattacata ctttgttata cttaaattag ttttcaatgc
    19621 aactacattg tctactattc taaaagattc taagtctcca ttaacaggta ctccttgttg
    19681 catacaagtt ataataaata ttcccattaa ataaacagaa taaattacta atggaactaa
    19741 taaagcaaca aatattttag actttaatgc ttttttcttc tcttttgatg atagtatgat
    19801 atcttttacc gaagtaacga cttcatctac ataaatattg gatataatta tagatataat
    19861 gattaacatt cctacattta taagtgaatt tgtgactcta tagttaaata ctttccaaaa
    19921 actaatatcc ttatattcat tcacacttag attatcaagt tttttctttg acattaattc
    19981 aattttttta gaaaattcac ctgtatctgt ttgatttgaa aactgcttta aaacattaat
    20041 cttattttga aatttctcat tacctacgtc gataccactt ctcgtatctt ctatacgtcc
    20101 tttttcttta tctatataat aactttctgt ttctaaaaca ggcgtaataa agatactaat
    20161 cattagtatt aacactaata tccctagaga tataaacata ctcttagatt tagccaattt
    20221 ttttatttcc caatttacca atatatttct cctcctaaat cattttaatt acacatatat
    20281 attaaaactt aaatcttata taaatataat actaacctta aataaagctt aaattatttt
    20341 ataatttata ggtgtgttta ttattggagt tacatttatt atttttctgg gaaattatac
    20401 attttcaatt atttttatta tttttgatat ttttattgat tggaaatttt attgttgttc
    20461 aaattgtagt tattctttaa atttaaagat ggagtttttt aagaatagaa cctactgtcc
    20521 ttattatgga aagattatta aatagttgca tataacttta tttatcttga atcttatttt
    20581 taaaaacaat tataatttta gaatattttc tattctcaaa caagcatgtt gaataatgga
    20641 gcatcttcta gtattatata cttgtagaat aaaactaaat tggtaaaact gggaatattt
    20701 aaccttaagg agttaagtta tagaaactag tactaaaaaa ttttataaat tatgttaatt
    20761 gactaataga atgcgacttt ttatttttac taaatttttt agggggatgg ataatatgtt
    20821 tattggagaa atagacaaat gtacacatat actaactgct tacatcagta gttcatatga
    20881 ttattgtaat tttttagata cacagttaga tgattttata tcagaatatg gagaaacggt
    20941 agttgaaacc tgcttacatc aagtcttatt attagtaagt agatacaatt aaaactaaat
    21001 ttttctagaa aaaccttttt agatttatct actctaataa atatataatt ttttgtactt
    21061 tataagtaac tataacttct gctaaagtaa agatgtattg ggagtacatc tttactttcc
    21121 cattatagaa gttaaaagca tacaccataa aattaatcat ccaatacaaa ttatatattt
    21181 cctatgtcta acttaattta caagaatcat tctatatgca tattctgcaa tccactaaac
    21241 atggctctaa acctttacta ttttatacat tctctataaa tcatacaaat catatataaa
    21301 atccccctaa tatgtttaaa ccacctataa aataacacca atatttagaa tattcaatat
    21361 caactgcata actggtcaat aaaaacgtat aactagacaa atttcaatat ttatataaat
    21421 aatacaagaa aaacaagcat tttatttata taagtttttt atttttt
//
LOCUS       DAMJWC010000061        21456 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMJWC010000061 DAMJWC010000000
VERSION     DAMJWC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.061"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            292..1563
                     /gene="serS"
                     /locus_tag="PC503_002797"
     CDS             292..1563
                     /gene="serS"
                     /locus_tag="PC503_002797"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2528763.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            1841..3346
                     /locus_tag="PC503_002798"
     CDS             1841..3346
                     /locus_tag="PC503_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2528764.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3460..4158
                     /locus_tag="PC503_002799"
     CDS             3460..4158
                     /locus_tag="PC503_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2528765.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4443..5531
                     /locus_tag="PC503_002800"
     CDS             4443..5531
                     /locus_tag="PC503_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528766.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            5770..6960
                     /locus_tag="PC503_002801"
     CDS             5770..6960
                     /locus_tag="PC503_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528767.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            7051..8553
                     /locus_tag="PC503_002802"
     CDS             7051..8553
                     /locus_tag="PC503_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2528768.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            8625..9881
                     /locus_tag="PC503_002803"
     CDS             8625..9881
                     /locus_tag="PC503_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2528769.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            10053..12827
                     /locus_tag="PC503_002804"
     CDS             10053..12827
                     /locus_tag="PC503_002804"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2528770.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(12892..13077)
                     /locus_tag="PC503_002805"
     CDS             complement(12892..13077)
                     /locus_tag="PC503_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2528771.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            13452..14630
                     /locus_tag="PC503_002806"
     CDS             13452..14630
                     /locus_tag="PC503_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2528772.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      14757..14842
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            14960..17878
                     /locus_tag="PC503_002807"
     CDS             14960..17878
                     /locus_tag="PC503_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2528773.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     ENENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNLGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      18064..18149
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18249..18911
                     /gene="zmp1"
                     /locus_tag="PC503_002808"
     CDS             18249..18911
                     /gene="zmp1"
                     /locus_tag="PC503_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF2528774.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(19033..19995)
                     /locus_tag="PC503_002809"
     CDS             complement(19033..19995)
                     /locus_tag="PC503_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2528775.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(20165..21355)
                     /locus_tag="PC503_002810"
     CDS             complement(20165..21355)
                     /locus_tag="PC503_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2528776.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
BASE COUNT         8472 a         2484 c         3677 g         6823 t
ORIGIN      
        1 agttaataac tatacaagat tgataaagaa aaagtcaaaa tagataattg attagcaaaa
       61 tagatataat tataatgaag ttaaatctag caatattctc ctaaaattaa attacattta
      121 tttaattaaa tataatttga caatggacaa aaaagtgagt aaaatataaa taaaataaaa
      181 ataacaggtt cggataaaga aaaaggtttc ttaacctcaa gcataaagta tattatctaa
      241 gttatttgag attaagagat aaatccaatc ttaggtactg aggaggaaaa aatgcttgat
      301 ataaaaagaa taagagaaaa tttagattgt ataaaaaaag caatggaaag aaggggcgaa
      361 aaagacttta accttgatga agtagttaag ttagatgatg aaagaagaaa gattcttcaa
      421 gaagttgaag ttatgaaaaa tgaattaaat acagcatcta aaaatatacc aaatcttata
      481 aaagaaggta aagatgtaga aaatgaaaag attaaactaa aagagttatc tgataaaatt
      541 aaggtaatag accaaaatct taaagaagta gaagataaga tggaatacct attaatgaga
      601 ataccaaatg taccacatcc agaagtacca caaggtgaaa ctgatgaaga taatgttgaa
      661 gtaagaactt ggggaaagac tactaccttt gattttgaat ctaaggctca ttgggaaatt
      721 ggaacagaat taggtatact tgattttgaa acagctagta aaataactgg ttcaagattt
      781 actctttaca aaggattagg tgctagatta gagagagcat tattaaattt ttacttagac
      841 acgaatacaa aagtaaatgg atatacagaa gttattccac catttatggc aaatagaaat
      901 agttttttag gtacaggaca gttacctaag tttgaagaag atatgtttaa aatagaaggt
      961 atggactatt ttatgattcc aacatcagaa gttcctttaa ctaatataca tgctaatgaa
     1021 atacttaaat ttgaacaatt accgataaat tatacagctt atactccatg ttttaggtca
     1081 gaagctggtt ctgctggaag agatacaaga ggtttagtaa gacaacatca gtttaacaaa
     1141 gtagaaatgg ttaaaatagt tgcaccagaa gaatcttaca atgagttaga aaagcttact
     1201 aacaatgcgg aaactatgct acaattattg aatctgcctt atagggtagt aaagatatgt
     1261 acaggtgatt taggatttac ggcttctttt aaatatgatg tagaagtttg gatgccaagt
     1321 tacaataggt atgttgagat ttcatcttgt tcaaactgcg aagatttcca agctagaaga
     1381 gcaggaataa gatttaaaag agataaagat tctaaagctg aatatgtaca cacattaaat
     1441 ggctctgggt tagctattgg aagaagtgtt gcagctatat tagaaaatta tcaacaagaa
     1501 gatggttctg tggttgttcc tgaagtttta agaccatata tgggagtttc tgttattaag
     1561 taagagttaa attatgtatt tttaagcaat acaataatat agaggtaata aaaaataatt
     1621 aatataaaag tgatacaata atatagaagt aataaaaaaa tagttaatat aaaagtgata
     1681 caataatata gaagtaataa aaaaaaataa ttaatataaa aatgtgtaca aactaatgaa
     1741 tattgatata gtaagctatc atatgaaaga gtatgtacac atttttttta ctaatttttc
     1801 acaatatgaa cataaataat ttacaggaaa ggaatctttt atgaaaattc aaaatactga
     1861 gtggggatat attgaatgga aacatactta tgatgaaaat aatccaaaac aagctatgaa
     1921 tatatacatt gcagtaacta tgcctggtaa gaaacatttt aatcatgttc attatggtca
     1981 agagcagatg atatatattt tagagggaga gggtttgtat attataaatg gagtttggaa
     2041 gccattttat caaggtatga ttttttatat agaatctggt agcacacatg aaactataaa
     2101 tacaggtgat agagaaataa aagaacttat tgtttcaaat aatgtagatg atgtaggaga
     2161 gagtgaagtt atagatatta atcctaataa ttatttaaag aagaccttga taaattatag
     2221 tgaaagtaca ttaaatttgt atgcagcagt agaatcaatt cgtggtcaat ttatagaccc
     2281 gtttaaaatt ccattaatta tatatgatga ttcatggaat atagttttaa aaaatcctta
     2341 ttttccactt ttttgttttg aaaaatgtaa tcctatgaaa tttcctcaaa attgtgattg
     2401 tatgaatcaa aaaagtagca atcaatttgt atgtgaatat gggataacta tatataatat
     2461 accaatactg tacaaaagca atagcatagg tgttataaga ggagggtatg tactattatc
     2521 tgatttgaat ttagatacag agcataataa tttatatgat attccagagg gagctgctag
     2581 aagtataaaa cgcctcttga aacaaatatc taaaaatata ataaattttt gctcttttaa
     2641 tgatataaga aaggatttac aagaaaaaga gaagactata gcaagaacat atcattatgg
     2701 agagcaactt gaaatgaatt taaaagtagc tcaagatatg gttactaatt taagaataaa
     2761 tcatcacttt ttatttaata cattaaattc aatggcaagc atagcactag atgatggtag
     2821 ttatgatttg tatagtgcaa taatagattt atcaagaatg tttagatata caatgaggtc
     2881 tgatttaaga tttgtagaat tagaatctga aatattatac attaaaaatt atttgaattt
     2941 acagaaatta cgttatggag atgcacttaa agtaaaatat cttattccag agaagttata
     3001 taacctttct gtgcctttta actttattca acctattgta gagaatgcat ttacacatgg
     3061 atttagagat attgacacag aaaagcgaat tgaaataatt gcaagattag attctcagta
     3121 tgctattata gagattcata ataatggaac tatcttagat ggaaataata tagacaaaat
     3181 aaaggcaggt attcgtagta ataatggtca tggtttgtct ttaatatata caaaattcac
     3241 atctgcttat ggaaataatt ttgatatgga tataaagtcg agtgataatg aaggaactta
     3301 cataatgatt aaaattccta ttgaaaatta taaggagtat gtatagaact tgtgaaaaat
     3361 taataagttt tataaatgtt aagaaatata ttagatgttt ttatgttgtt ttatatatct
     3421 tactttttta tattattaag ctaaaaggga ggtattctca tgagaagagc actaataata
     3481 gatgatgaag aagctgttct aaaaataata acacatttta tagaaatgaa agatatgcca
     3541 ataaaaattg ttggtaaagc aacatctggt gatgaagcag tagataaaat cattggttta
     3601 gagccagaca tagtttttat agatattcaa atgccaatat acaacgggtt agaagtaata
     3661 gaaaaaacat ctcatttatc taaaaaaata aactttgtag taataactgc atttaactat
     3721 tttgaatatg ctcaaaaagc tttgagatta aatgtaaaag atatactcct taaaccattg
     3781 gatatgaaag aatttactaa gtctgtagaa aaaattattg gatatcaata taccaataat
     3841 gatttattaa atgagatact ggaatatata aatctaaact atagcaatga cttaaagtta
     3901 aatgattgtg ctagattatt tttaaccaat ccatctaata tatctaggat ttttaaaagt
     3961 aatttaaata caacttttat atcatatcta aatcatataa gaatagaaaa atctattgag
     4021 ttacttgaaa atactacaaa aagtataaat gagattgcag aaatagttgg atataatagc
     4081 ctaaataact tttataaaaa ctttaagata gaaaaaggaa tgactccaaa agtttataaa
     4141 ctgaacacta aaaattgaaa ttgataaata aaaagtcaat atagataatt gtttgagtgt
     4201 gtctgaataa gtatacttta attatgataa aaattaaagc gctttaaaca tatttaataa
     4261 tattaaacct tataaaagct gtacctattt atataaaaaa atatatataa ataaaaagaa
     4321 aaagatatac aaaataaaaa aagtgaatta aatactgttt caaaaagaca gaattttcat
     4381 ttaatttact gagagtttat atttcttaaa ggaaggtaac tttataatgg aggtaattta
     4441 atatgtcaga caaagtgaat atgaaaaata ttatctgtat tgcaggcgct tatctagcaa
     4501 cagcaattgg ttctgggttt gctactggtc aagaaattct acaatttttt gcctcacaag
     4561 ggtatatggg tttaattgga gcattaatat caatggtatt gttttcattt cttggtgctg
     4621 aagttataac tagaggtaga gaattaaaac ttaaagaacc aacaagaatt tacacttttt
     4681 attgtgggaa gattttagga aaattttacg aatggtttag tccaatattt ttatttggga
     4741 ttcttatagt aatgatttca ggtgcaggct caactttaac tgaatactat ggtataaatc
     4801 cttacttagg aagagtattg atggctgttg ctactttaat tacagtgtct atgggtttag
     4861 aaaaattagt aagcatactt ggacgtattg gaccagtgat agcagtattt acaattgctg
     4921 ttggattaat aagcttgttt aagcattttg atggtttatc tatggttgga gaagctatga
     4981 aaaatattga agttacaaaa gcatcagaaa gtccaatcgt ttctggtgta atatataata
     5041 cattaaatat tattgtaatg attgtttttt taacaggaat gggagcttct attgaaagta
     5101 aaaaggatgc tttttgggga ggtttattag gtggaatagt gtttatgact gctggtatag
     5161 ttatgtattt ggctatgatt tcagatatag gaaatttgta tatgaaagaa ataccatcac
     5221 tttatttagc agataatata tctcctattg taggtgtatg tttttcagtt gcattaatat
     5281 taggtatcta cacaacagct gttccacttt tatggtctgt aaccaataga attgttgaag
     5341 atgaacatcc taaatttaaa ttggtaacaa cagtaatagc tattttggct tgtataggag
     5401 gttttttacc gtttggtaaa ctagtaaaca ttttatatcc atatacaggt tatatggggc
     5461 ttttaatttt agtctgtatg gtgtataaag caattacatg tagaaaaaaa tcaacacaaa
     5521 gtcaggaata gagccactta ttaatagttt ttatttaaag aaatttttta tataatccga
     5581 atttaaaaag tcaaaatagt taaataaatt gtaaaatatg ataatatatt taattaaaat
     5641 aatatagtaa aatataaata taaactaaaa ttaaatttat aaaaaatatc tttataaaga
     5701 ttattaactt atataatttg tagttaaatt ataaaaaata aaaaaataaa attttggaga
     5761 ggtgttagta tgcatgaact tattttaatc tcagaaaagt ataaagaaga tattttagat
     5821 ttttttacag atattcatat gcaccccgaa ttaagtttta aagaatttag gactacaaaa
     5881 gctataaaag atttattagt gagtttagac atagaaatat tagatttagg aatggaaaca
     5941 ggagttgttg gattattaaa agggaagtat gatggtccca cagtagcact aagaggagat
     6001 attgatgcat tgccaatata tgaagaggtt gatattaagt ataaatccag atatgatggt
     6061 ataatgcatg catgtgggca tgatatacac acgtcttgcc ttgtaggatg tgcatatgta
     6121 ttgtctcata ttagagatag tcttcatgga aatgtaaagt ttatatttca accagccgaa
     6181 gaagtcaata aaggtgcgaa gatgctagtg gaacgaggag taatggaaaa tccaaaagtt
     6241 gatgctatat ttggacttca taatcatcca gatatacctt gtggaaaaat aggtgttaag
     6301 ttaggtgggt taatggcagc agtagacact attaagatag aagtaaatgg atttggaggt
     6361 cacggaggta tacccaacag aacaatagac cctatagtag catcaagtgc aattataatg
     6421 ggtattcaaa ccatagtaag cagaaacata agtccattag aatcagctgt tatatcaata
     6481 ggtactataa atggagggac tgcaaataat gtaatttcag aaaaggtaga tatgacaggc
     6541 acatgtagaa gctttagtaa tgaagtacga aagaaaatat cagaaaattt agaaaatata
     6601 gtttgtgaga tagctcgtgg atatcaagca actgcaaagc tagattattt atttgattta
     6661 ccagctgtta taaatagtaa agagatgtac gcaatagctt gtaagtctgt gtgtgatttg
     6721 tattcagaag atgctatagt tgatccaata ccttctacag gaggggaaga tttttctata
     6781 ttcatggaaa aagccccagg atttttttac tggttagggg taggcaacaa agaacaagat
     6841 tgtatatatc agtggcataa tcctaaattt aaagctgata aaaattctat attggtaggt
     6901 acaaatgtac tatgtcagtc tgttataaat tatatggata aattaaaaaa taaaatttaa
     6961 gatagagcat tctggagata aagtttatga gggggtatta gtttgaggaa aattaattca
     7021 caggaaaaaa acaaagatag tggattattg atgagggcac taaatgttgt agagagagca
     7081 ggaaataaac ttccagaccc agtaaccata tttttattac tatgtataat tgttgtaata
     7141 ttgtcagcag ttatatctaa tttaggagta gaagaaatac atccttctac aaaagaagtt
     7201 gtaaaggtag taaatctact agagaaagag cagattcaat catatttagg tagcatagtt
     7261 acaaactttc agtcatttgc tcctttagga ttagtactgg ttacaatgct tggagcaggt
     7321 gttgctgaga aatctggatt tatggaagtg ttaatgaaaa agggtataag taaagttcca
     7381 caaaaacttg taactgtagc aatcgtattt gcaggtatgt tgtcacatac agcagcagat
     7441 gtaggattta taatattacc accacttgca gcacttgtgt ttttaggaat tggaagacat
     7501 cctcttgtag gtatgtttgc agcttttgca ggtgttgcag ggggatttgc agcaaatgtt
     7561 atgcttagta ctacagatgt attgttagct ggatttacaa taccagcagc tcaaatgatg
     7621 gacccatctt accaaggcaa tccagcaatg aatctttatt ttgcttttat atcagcgata
     7681 gttttaactt ttgcaggagc atttgtaact gaaaaattta tagctcctcg ttttacaaaa
     7741 tataatgatt caacaaatga taaggatata caggaattga gtgaacttga aaataagggt
     7801 ataaaatacg ctttattatc attgttagtt gtagtagtag tgatagttgc cttatgtata
     7861 ggtgacaatg catttatgaa agatccagag actggttcta tactatctag taatgcacct
     7921 ttaatgaaag gtatagttcc tataatcact attatatttt taactccagg attagtgtat
     7981 ggaaaagtaa gtaagaagat aaaaagtgac aaagatttag tatctatgat gggtagtagt
     8041 atgagtgata tgggtggata tatagtccta gcatttatag catcccagtt tattaattta
     8101 tttaatctta gtaacttagg aacaatttta tcaataacag gagcaaaatt actagcagag
     8161 tcgggaatac ctagctatgg attgataata ggatttatat tgctatctgg atttatcaat
     8221 ttatttgtag gaagtgcttc tgcaaaatgg gcgattttag cacctatatt tgttcccatg
     8281 tttatgctac tagactttaa tccagcatta actcaaatag cttatcgtat tggagatgct
     8341 tcaacaaatc caataagtcc actttttccg tattttccag ttatattggc ctttgccaga
     8401 agatatgata aagatatagg tataggtact gtcatatcga atatgattcc atactcagtg
     8461 gtatttacat taatagaaat aataatattg ttactattca tgggtattgg cataccatta
     8521 ggacctggtg gaggaatatc ttacgtttta tagaccgtta taataaattt atcaatgaag
     8581 attaaactaa taaaatatat tctttaatta agaggaggat tattatgtta aaaacaacaa
     8641 aaatttcaga cccagagtta tacaagattg tagctgatga gttggttaga caagaacaca
     8701 atattgagat gatagcttct gaaagtacag caccaacaga agtacttgaa ttaagtggat
     8761 gtgtatttac aaataaaaca gaagaaggct atccaggggc tcgttttcaa gcaggttctg
     8821 aagaagcaga taaacttgaa accctagcaa taaaacgtgc aaaagaagta tttggagcag
     8881 aacatgtaaa cgtacaaccg tattcaggtt ctacagctaa ctattgtgta tattcatcaa
     8941 tattaaaacc aaatgacact gttttaagta tgcgtcttga ccaaggtgga cacttgacac
     9001 atggtagcgc agttaatttt ttacatgaca tttataaata tgaattttat ggggtagacc
     9061 caaatactgg acgtatagat tatgatgctc ttgaagcaaa ggcaaaagaa tgtagaccaa
     9121 aacttataat tgcaggggca agttcatatc caagattaat agattatgaa agaatatcaa
     9181 aggttgcaaa agaagtagga gcttacttta tggtagatat ggcacatgtt gcaggattag
     9241 tcgcagcgaa agtaatacct agtcctgtac cttatgcaga ttttgtttct tcatctacga
     9301 caaagacttt ctgtggacca agaagtggta ttgtactttg taaagcagaa catgcaaaga
     9361 aactcgataa aggtgttttt ccaggaacat taggttctat acatcttaat acagttgcag
     9421 caaaagcctt ttcactatta tatttaagta cagataaatt taaaaagata atggagcaag
     9481 ttgtagtaaa tgctcagact ctagcttctg aactgatttc acatggtttt agtattgtaa
     9541 gtggaggtac tgataatcat atagtaatgg ttgacttaag aagtaagaat cttacaggaa
     9601 aacaatttga aaaagctctt gaatatgtag gaataacagt taataaaaat gttatacctg
     9661 acgacccaca atcaccattt gtaactagtg gtgttcgtat aggtcttaca tcaatatctc
     9721 aaagaggtct gaaagaaaaa gaagttatac agatagcagg gataatgaat aaggtagcag
     9781 aaaatattga taataaagaa gtattagatg aatgtaaagc agaggcacaa gaacttatat
     9841 ctaagtttcc attatatcca gaagggtatt ttgaagatta aatattttga tttgtatagc
     9901 tcacaattta taaagcctgt aacataaaat ttaataatat ataaccacta taaggtgttg
     9961 attaatcaac accttatttt ttttgaaaag taatatacaa gctatcataa gcatataatt
    10021 ccttatagat aattaacaag ggggataaag ttatgaggta ttataataaa cctaccaaag
    10081 aagtattaaa atacttaaaa acaaatccag aaattggact tgatgataat gaggtagaag
    10141 aaaggaagct tagatatgga ttaaatgaat ttactataaa agaaggtaga acattttggg
    10201 acgagttggg agaaagtttg acagaaccta tgatattaat tctcatagga gcagcagtaa
    10261 taagttcttt tgtgggagaa ttacatgacg cattaggtat tttaggggct atttttattg
    10321 gaatttctat aggcataata actgaaggaa aatctaaaaa agcagctcat gccctgtcaa
    10381 aattaacaga aaatatagaa gtaaaggtgc ttagaaatgg gaagataatt aaaatatcaa
    10441 aaaatgattt agtaccagga gatattgtat atatagaaac tggggatatg ataccagcag
    10501 atggaagact tatacagtct ataaatttga aacttagaga agatatgcta acaggagaat
    10561 ctgatgatgt agctaagaat gctgatgctg tattagatat ggaagtagtt tattctaaaa
    10621 cagaaataat cgaacaggat gcaatacctg caaagcaagt caatatggta tttggaggga
    10681 ctcttgtagc atatggtagg ggcataatgg ttgtcactca tactggtgat aagacagaga
    10741 tgggtaagat agcacagaat ttatcaaatg aagaccagca aactccactt caaattaaat
    10801 tagggaagtt gggtgctaaa atagcaggaa tatcaggcat aatagctact ttattgtgta
    10861 tgtttatgat tatacagatg cagagaaaag gtatgttaat tttagataca agcagtatat
    10921 tatctttctt acaatcatta gaacctgcta aaaatgcata tatggtttgt attgcattaa
    10981 tagttgcaac tgttccagaa ggtttgccaa ctatgataaa tattacctta gctataacaa
    11041 tgcaaaagat ggcaaagata aatgcattag taacaaagaa agaagcctgt gaaactatag
    11101 gttctgtttc tgtaatatgt tccgacaaaa cagggacttt aacacaaaac aaaatgatgg
    11161 tagaggtagc atatgttgat ggtaaatata taagtggagg agagtatcaa agtaatagct
    11221 attttgaaca aaactgtata gtaaattcaa ctgcagatat agaaaaagaa gataattcat
    11281 ttaaatatat aggaagcgca acagagtgtg cattactttt atatcataat gataagaact
    11341 ataatgaaat gagaaaacaa acgtatttga tatcacaaat accatttagt tcagaagaaa
    11401 agaagatgtc aacattaatt cgtcaagagg attcagatat attactttca aaaggtgctc
    11461 cagaagtatt attaaaaaaa tgttcttatg tacaacaagg aaaaaatatt gttccaataa
    11521 ctccaaaagt agaaaaaagt attttagatg agattaagaa gttacaaatt aaatctatga
    11581 gaacattagg atttgcttat aaaaaaatga gtaattctaa aacagaagtt gcaatgactt
    11641 cagaaggtga attgaattta ataggaaatt caagaagtta tatgaaggaa gataatttag
    11701 tttttagtgg atttgtagga atagtggacc cattgagaga aggggtcaaa gattccattg
    11761 ataaagcatt taatgcagga gtagatgtaa aaatgcttac aggagataat ataaatacag
    11821 caacagctat tggaaatgaa ttaggattat taaatgatgg gaaaaaggca gttgaagcaa
    11881 catatataga tgtattgaca gataaagaat tgagagaaga aatcaaagga atatctattg
    11941 ttgcaagaag taaaccagat acaaaaatga gaatagtttc agcacttcaa aaaagtggcg
    12001 aagttgtagc tgtaacaggt gatggtataa atgatgcccc agcacttagt caagcagatg
    12061 ttggaattgc aatgggtatt tcaggaacag aagtatctaa aaatgcagca gatataatat
    12121 tgactgatga tagctttagt actatagtag agggaataaa atggggaaga ggtatatatg
    12181 agaactttca aagatttata cagtttcagc ttactgtaaa tatagtagca tttataattg
    12241 ctataatatc tcaacttact ggtaaggata tgccatttac tacaatacaa ttattatggg
    12301 taaatataat aatggatggt cctccagccc tagcattagg attagaacct gttagagatt
    12361 atgtattgaa aagaaaacca ataaatagac attctggaat aatagctagg tctatgtttg
    12421 taaatattat tataaatgca attcttataa ttacaattgt atttactcaa tcagctttta
    12481 atatattggg agctacatca gaagaacaag gtactgttat attttcttta tttgcattca
    12541 gtgccctttt taatgcatta aattgtagag agtttggttt aaatagtaca ataccaaatt
    12601 tctttaaaaa taaactggca ttgcaaataa tagtagttac agggataatt caaataatat
    12661 ttacacaagt gttccagagt ttctttaatt ctgtttcttt ggactttgat atgtggataa
    12721 agataatact atttgcatcc actatcctat tgtcaaatga atttgtaaag ctaattctta
    12781 gaacaatgaa aaatagtaga actatgaact ttaatagtaa aaattaattc ttatgaaacc
    12841 gtaaagtact atatattgta actttgcggt ttttgtttgt ttaatgttgt tttatattac
    12901 cattttcata tttaattttt tattaatctg aacacaatct tccattgtaa ttgcttcatc
    12961 tgtgtcaaca cattcaaagt caatatctaa tttttgtaat attttatatg cctctttttg
    13021 caaaggagta tcaaatttaa taggtgattt tgtgtaaata tcactgataa aaaacatgat
    13081 ttatttcatt cctttccatt taaaatctta tagttatagt gtatcataag gttataaaat
    13141 atagataaat atagtataaa tttaaaatat gtacagacaa aacaaaaaaa tcatattcta
    13201 agtaatactt gggaaaaatg atattatcat aataaataat ctttgtaaaa acttatatag
    13261 aatctattaa acagacacta agccataaaa actttactaa atataaaatt cgtatctaaa
    13321 tagatatata gaataatatt ttactgaagt agagtgattt ttaagaattt tatatataaa
    13381 ttatgttatc ataaataaag atatagatta taaaatttgt taataaaata aagggcaggg
    13441 aggtaagttt catgttttcc aaaatcctag tcaaaacatt tatcagagat agcgaaaacg
    13501 ttcaaaatac agatgttaga aataagtatg gttatgtagc tggtgtagta ggtatattat
    13561 ccaatttact tttatttgtg ataaaggtat tcataggaat gctcacatct agtatagcta
    13621 taatggctga tgcatttaat aatctttctg atatggcatc ttcagcaata actatgatag
    13681 gttttaaatt agcaagtaag ccagctgata aagaacaccc ttttggtcat ggaagaatag
    13741 agtatttatc agcattaata gtagcattta tggtgatgtt ggttggactt caatttgtaa
    13801 agtcatctat agaaaggata gtaaatccaa ttcctgtaaa atttgaagta ataccactta
    13861 tacttttaat tgcatctata atgattaaaa tctggttgag tcgttttaat aaatttatgg
    13921 gaaataaaat tgattcttca gccttaaaag cagtttcact tgatgcttta ggagatgtat
    13981 ttacttcaag ttgtgtagtt atatcattta ttgtagctag atttactaat tttcccatag
    14041 atggatatgt tggtatcgta gtatcattag tgatacttta tgctggtttc tctcttgtaa
    14101 aagatactat aaatcctctt ttaggggaag caccggatga agaaatggta aattctatta
    14161 tagagctatt gttatcttat aaatatataa taggtacaca tgatttaatt attcataact
    14221 atggagttgg tagatgtatt gcatctatac atgcagaaat tccatccaac atagatataa
    14281 tggaaataca tgaaattata gatactgcag agagagaaat atctgaaaaa ttagatatat
    14341 atctagtaat tcacatggac ccaatatgtc ttgaagataa agaagttatg tcagccaaaa
    14401 aagaacttga agaaatactt aagaaaaata gtcttgtaaa atctatgcat gattttagaa
    14461 tagttggaaa aggaagcaag aagaatttaa tatttgatat agtagttaat ccttccgaat
    14521 tttccaaaaa catgtcagaa gatgacttaa aagaagatat aacaaaatta gttaaggaga
    14581 taaatcctga atataattgt gtaattgttg tagataagga ttttatttaa ttattaatta
    14641 atctcatcat aaggtaaaaa atgtaaaaag gatagacaat agtatagagg cataatataa
    14701 tagaagtata taattgtatt tttaatataa ataaagcaat tttaattgtt tttatgaaat
    14761 attatagaga tgttgaagta tattctatta ttgggcacct tatggatata ctgagtcagt
    14821 ggtgcaaccg gctatgaata taaatttatt tattttcata gctttttttg tataattttt
    14881 tagtaaaaat tactttatat acgatattaa tggaagatta gattataaat tataggtaac
    14941 ctaaaggggt gagatttaca tgaagaaagg aaatagaaag gcattattaa ttagtttaat
    15001 tatgatttta agtatggtgg tgtctacaat atatccaact gtatcttatg cttcggaatt
    15061 aggagagaat agtcagattc aaagtggttc aactaattca tcaactggag aggagaagga
    15121 aagcgacaat aaaaagccag aacagactcc agagaaagat aaggcaacag ataataaaaa
    15181 accagaacag accccagagg aagaaaaacc aacagataat aaaaaaccag aacagacccc
    15241 agaagaagat aagtcaacag ataataaaaa gccagagcaa actccagaag gagaaaagcc
    15301 aatagataat aaaaagccag agcagatacc agaagaagat aagtcaacag ataataaaaa
    15361 gtcagaacaa gctttagaag atgaaaaacc actagacaat aaaaatacag aaaaaactcc
    15421 agaggaagat aatctattag aaaatgaaaa tttattgaaa gttttagaag aagaacttaa
    15481 tgaagaaaat gaagactatg gatttgttgt aaaaattaat aacaatacaa tagaaacgga
    15541 atcaatgaaa aaaatatcat ttaatttaac ttatactcca acatcaaaag gaatacaagc
    15601 aggagattca ataactttta aggtgccaga tgtattcaat aaagttaatt tagattatac
    15661 aagtgaatgc tttgataaaa cagaaagtaa tggagagtat acacttacat ttagagaatt
    15721 acctaatggc caaagtgtaa tgcaaggtaa aataggtttg gaagcatatg ttaaaaaggt
    15781 tgatgaagat actaatgcaa aaatacatat tgaaactact ggaaaaatag aaagtggaag
    15841 tggagatata gatgtagaaa taaaacctgg agataaaacg gatgttccag atgctaaagg
    15901 aacacttaaa aagcttgttg aaggaaaaaa atcaactact gtatttatgc cagttaaaaa
    15961 taaagatata aattacagta tacaagtaaa tgaaaagcag gaagagttaa aagatattat
    16021 tttgtatgat gagcttcctg aaggattgac attgataaat ggttctgtaa gtgtagtaac
    16081 aagtgatgga aaagaagtta gtgattttaa tattgaacag agtaaaaatt ctatttcagt
    16141 taatcttgga aatatagata aatcgtatac tgttaagtat aaggctagaa tcagtgacaa
    16201 aaatgcaaaa catggtaata aatataagaa tgtagctagg attgaatctg atggtaagaa
    16261 gatacaagaa gatgatgcta ctgtaagtat atttgataga ggagatgatt atcttcttac
    16321 taaaggacat tcaggagcaa caaatattac tcaagttggt caagtaataa actatcagat
    16381 ttcaataaat gatgataaat caccaataag taatgttgtt ataacagata atataccaga
    16441 aggcatgaga ttaactactt caggagaagc tgggcatgat tttagagttg tagaaattcc
    16501 aatgaatggg agctggactc cttggagtaa agaaaaaatt gccaataata tttcatataa
    16561 agtagaagaa aaaagaaatg aaagtgggca agtagataaa gttataactg gatttacaat
    16621 taatctcagt aaagaagaag tggaatcaaa gttttttata gcttatacat taaaggtaat
    16681 tagtattgaa gatagctata taaatagagc tgttcttgat gcaaataata gtgaaattga
    16741 taaaaatgat gagataaact ttaagaaaaa ttctggatta ataagcgcaa aaaaagaagt
    16801 tgataaaaaa gttttaaata gtagtgataa ccagattgtt aaatacaaaa tcaatatgtc
    16861 aacttatggg gtttatgatg caggacaagt aaatctttta gatgaagtaa actcagctct
    16921 agaaatatct aatataaaat attctgataa tcttgaactt aaaaaagaag ctggagatgg
    16981 aaaaaataca ataagattag taaataaata cgaatttaaa cagataaaag aaggggaacc
    17041 tgtgcaaagt tgggttacat ttgatgcaga cttcacaaat gtaaaagttg gggagactat
    17101 acgaaatgtg gctcagatta atggttcaag tcctccagga gtagagacta ctaagcaagg
    17161 ttatgctttt gaagctaaaa aagtggatgc tttagataaa aatgtacttt caggtgctaa
    17221 gttcaattta gaagatgcat ttggaaatat agtagttaag gatttagtta gtgatgaaga
    17281 tggtataatt caatctagta taaaaaaacc aggaacatat tatttagtgg agataatggc
    17341 tccaagtgga tatgaaaaac tgaaggataa aattaaggtt gaaattggta ataaagatat
    17401 tggtagaata gtggatattg gaaatataga aaacataaga caagaaaatc caccagtaaa
    17461 tccaccagca ccaccaaata cagatgaacc aatagtaaat ccaccagtac caccaagcac
    17521 agataaacca aggaaaccat caagttcatc tgatacagag gatactatag ttataaatcc
    17581 accaatacca ccatcagaag atataataaa tccgccaata ccagaggtat tgaatccgcc
    17641 agtaccacca tcagaagaga tgatagaaac tcctgttaaa cagattattc caataccaga
    17701 agtagtaaag ccatcagtgt cagaagaaaa aaataataaa gttaaagatg atactttggt
    17761 aaatccacca gtaccaccaa aaacagggga tagtactaca attattggag aaatactttt
    17821 ggttatagga gctattgtag gacttatcgt attaagaaga aataaaaata caaattagac
    17881 cctaacatta taaaaaatat aagttatatt aaaaaatatc ttctaaaaca atatttaata
    17941 atgaaaatat tgttagaaga tatttttttt tgaagattta tgtaaaaaaa taataacttt
    18001 ttagaaaaaa gttccaaagg gatatagaca attaaaaaga tataagctat aatatagata
    18061 taaaattaaa tgaggcaaaa ctagggaaac ctagtcacgc aaagctatag gggctaaagt
    18121 ttagtaaacc atgccagcca gttgccgaaa agagtaaaaa tttctttttg tatatacaaa
    18181 gatactcttg ggtatctttt ttattttgaa atttattact cccggcctaa ctcaaaggag
    18241 ggaataatat gagaccaagt aaaaaattat taatagctat aatatcaata ttcttaataa
    18301 gttcagttcc agtaagtgca catgcagata gtactactat acaacaaaat aaagacacac
    18361 ttagtcaaat agtagttttt ccaactggaa attacgataa aaacgaagct aatgctatgg
    18421 taaatagatt agctaatata gatggaaagt atttaaatgc attaaagcaa aataacttaa
    18481 aaataaaatt attaagtgga aagttaacag atgaaaaaga atatgcttat ttaaaaggtg
    18541 tagttcctaa gggatgggaa ggtactggaa aaacttggga tgatgttcca ggtttaggtg
    18601 gaagtacagt agctcttaga ataggattta gtaacaaagg taaagggcat gatgcaataa
    18661 atttagaatt acatgaaaca gcacatgcaa tagaccatat agtattaaat gatatatcta
    18721 aatcagcaca attcaaacaa atatttgcta aagaaggtcg ttctttaggt aatgtaaact
    18781 acttaggtgt atatccagaa gaattttttg cagaatcatt tgcatattac tatttaaatc
    18841 aagatacaaa tagtaagtta aaatcagctt gtccacaaac ttatagcttt ttgcaaaatt
    18901 tagctaaata gagttttaat aaatttaaaa taaatataaa taaagagatg ctattataat
    18961 agcatctctt ttatattgcg tttaaatcta ataaattttg tcttatgtat aactatgata
    19021 gattatcaat tactactcct tatacaaggc ttcaacgtgt ttattatgca tttgagtaat
    19081 tatcgtaggt ataatagaaa ttattgaacc aattactatc aataaaattc ctataaccat
    19141 gtttataggg ataatttctt taagtattaa taatgctagt attggagata ttactggttt
    19201 aaagaagaat actaaagatg taagactagt agatgtagct tccattgcca taaagtaaag
    19261 cgcataacca acacctgtaa caaatacgaa tacataaatc ataatgggca tattgtgtaa
    19321 ggtatatcca ctaaaaatag ggatatttgc aaatacatga agcttatttt tatttaatat
    19381 atctgcgata aaattaattt tagtgagtaa aaccaatatc aacatttcca aactaccaaa
    19441 tataaagcta aagcaggtta caactattcc accaaatttt aaggtttttc ttttaccaaa
    19501 tacagtatac attgaaaaaa taatagcaga agataatgtt aagaatattc cactaagagt
    19561 tagttttgta tgcaatggat ttattataac tataattcca agaacttcta atataagtga
    19621 aattacattg tgcctatata ttttttcctt caaaattaag taagctaaaa gcattacaaa
    19681 gactggatta caactgaaca aaacagcaac tacagatgcc tttgtgttta gaacagcaag
    19741 ttgatacaat gacatactta ctactacaca cataaaacct aaaaatgcaa agtattttaa
    19801 gtctgatttt gtaatagaaa gactaagagc tcttaatctt tttacagcaa aaggtagtaa
    19861 gactaaaccg ccaacaaaaa atcttgataa agttatttgt aagggattaa agtcattagt
    19921 gacagttttt agactaattt ccattgaact aaaaaataag gtagtcagta ttatataaac
    19981 ataacctttt ttcaagtcaa acacctcctt gtaatttata ttagtactat agataagaat
    20041 attcaagcat attggaataa tatggtatgt ataaaatata gtacataaaa ttataaacta
    20101 ccttaatata gaatgtaagt attctatact aaggtagtta attatttgaa ttactttgat
    20161 ttagttattt taaattatat aatttggcta atttttcaaa tgctggtaaa gaacttttaa
    20221 ctttatcata agatacacaa tatgatactc taaaatgacc tggacaacca aaagaagaac
    20281 ctggtactaa taataaatta aattgttttg catcattgca gaatttttta tcatcttcaa
    20341 ttggagcttt tgggaacaaa tagaatgtac cattaggttt aacacaagaa tatcccatat
    20401 cgattaaact attatataga aggtcaaaat tctttttata aatatttaca tcaacttctg
    20461 catctaaact tcttgcaata accctttgaa aaagagaagg agcatttaca aatccaagta
    20521 ttctatttgc aacatttaat gaagacataa catcatcaaa atcatccatt tgcccattag
    20581 caacaatata tcctatacgt tcaccaggta gagataatga tttactataa gagtatccta
    20641 taaatgaatt tctatagtat tttagtacac aaggaacttt ggcaccatca taaattattt
    20701 ctctatatgg ctcatcagaa attaggtata tgcttgtatt aaattctttt tgttttgaat
    20761 ccaataattc tccaagattt tttaataatt cttcagaata tatgacacca gtaggattat
    20821 ttggagtgtt tattattaaa gctcttgttt ttggagtaat agcatttttt agagcatcta
    20881 aatctggttc aaaagtctct atatttgtag gaacttctat taattttcca tcatagtttt
    20941 ctgtataatt tttatactca ccaaaatacg gtgcaaaagc aataacttca tcaccaggat
    21001 ttaaaagagt ttttaaaata atatttagac caccagcagc accacaagtc ataattaaat
    21061 tttctcttgt aagatttaat ccatcttttt tatttatgtg ttcagcaata gcatctctta
    21121 catcctcata tcctgagttg ttcatatatc catgaactaa atttggagat tcttcattta
    21181 aaatatcatt tataactgct ttaatagtct ctggaggttc aacacttgga tttcctatac
    21241 taaaatcaaa aacattttcc tcaccataaa tatcagaaag tttctttcct tcttcaaaca
    21301 tagctcttat aacagaacta tttgcaacta aagtttgcat tttattagat atcatatgta
    21361 acactccttt ttatagattt atattgctta tgtatatatt accatatttt tactgaattt
    21421 agacaatttt cgaaaaatta cttgtttgaa aatata
//
LOCUS       DAMJWC010000062        20869 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMJWC010000062 DAMJWC010000000
VERSION     DAMJWC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.062"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            282..671
                     /locus_tag="PC503_002811"
     CDS             282..671
                     /locus_tag="PC503_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2528777.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            991..1500
                     /gene="vanZ1"
                     /locus_tag="PC503_002812"
     CDS             991..1500
                     /gene="vanZ1"
                     /locus_tag="PC503_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF2528778.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LIPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLVFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1602..1796)
                     /locus_tag="PC503_002813"
     CDS             complement(1602..1796)
                     /locus_tag="PC503_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF2528779.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2312..2704)
                     /locus_tag="PC503_002814"
     CDS             complement(2312..2704)
                     /locus_tag="PC503_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2528780.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            3271..3633
                     /locus_tag="PC503_002815"
     CDS             3271..3633
                     /locus_tag="PC503_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528781.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3617..4342
                     /locus_tag="PC503_002816"
     CDS             3617..4342
                     /locus_tag="PC503_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528782.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEDEEYEEELKQN
                     IIENIKKNFDEKNLVQVYKYRGV"
     gene            4362..4781
                     /locus_tag="PC503_002817"
     CDS             4362..4781
                     /locus_tag="PC503_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528783.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4771..5295
                     /locus_tag="PC503_002818"
     CDS             4771..5295
                     /locus_tag="PC503_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528784.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5607..6164
                     /gene="efp"
                     /locus_tag="PC503_002819"
     CDS             5607..6164
                     /gene="efp"
                     /locus_tag="PC503_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF2528785.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6256..6711
                     /locus_tag="PC503_002820"
     CDS             6256..6711
                     /locus_tag="PC503_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2528786.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            6874..7584
                     /locus_tag="PC503_002821"
     CDS             6874..7584
                     /locus_tag="PC503_002821"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF2528787.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            7638..8708
                     /locus_tag="PC503_002822"
     CDS             7638..8708
                     /locus_tag="PC503_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2528788.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            8736..12290
                     /gene="smc"
                     /locus_tag="PC503_002823"
     CDS             8736..12290
                     /gene="smc"
                     /locus_tag="PC503_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF2528789.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKFAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12317..13597
                     /gene="ftsY"
                     /locus_tag="PC503_002824"
     CDS             12317..13597
                     /gene="ftsY"
                     /locus_tag="PC503_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF2528790.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            13700..14068
                     /locus_tag="PC503_002825"
     CDS             13700..14068
                     /locus_tag="PC503_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF2528791.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14065..15417
                     /gene="ffh"
                     /locus_tag="PC503_002826"
     CDS             14065..15417
                     /gene="ffh"
                     /locus_tag="PC503_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF2528792.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPINIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            15455..15727
                     /gene="rpsP"
                     /locus_tag="PC503_002827"
     CDS             15455..15727
                     /gene="rpsP"
                     /locus_tag="PC503_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF2528793.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            15792..16019
                     /locus_tag="PC503_002828"
     CDS             15792..16019
                     /locus_tag="PC503_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF2528794.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16127..16642
                     /gene="rimM"
                     /locus_tag="PC503_002829"
     CDS             16127..16642
                     /gene="rimM"
                     /locus_tag="PC503_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF2528795.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            16651..17346
                     /gene="trmD"
                     /locus_tag="PC503_002830"
     CDS             16651..17346
                     /gene="trmD"
                     /locus_tag="PC503_002830"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF2528796.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            17531..17881
                     /gene="rplS"
                     /locus_tag="PC503_002831"
     CDS             17531..17881
                     /gene="rplS"
                     /locus_tag="PC503_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF2528797.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18202..19098
                     /gene="ylqF"
                     /locus_tag="PC503_002832"
     CDS             18202..19098
                     /gene="ylqF"
                     /locus_tag="PC503_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF2528798.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            19487..20779
                     /gene="brnQ"
                     /locus_tag="PC503_002833"
     CDS             19487..20779
                     /gene="brnQ"
                     /locus_tag="PC503_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2528799.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLFVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         8766 a         1954 c         3750 g         6399 t
ORIGIN      
        1 atcctgtatt taagcttata gattataatg aaatataata catgttgcaa taataaaacg
       61 aactaaaatt atcacactaa agcataaaac atactctaat catgttagat aaatttttga
      121 atatataatc caaaagtact ctctaaagta gagtacttct tttttattaa ttatttttat
      181 atagaataaa ttggaattta tatttattcc aatctaattg attacataca cttattgtta
      241 taaagtttag ttatacataa attggtaaga ggtgtaaact aatgaagatt aataaattac
      301 cacatgcaga actaaaacta atgaagtata tttggggagt agatgatgta ttagcctcaa
      361 gagatatcat agaagacatg aagttgaaat acgattggaa aaagagcaca acattgacat
      421 ttttaaaaaa tttagtagat aagggctttt taactactga taaggtagat agatgtacgc
      481 attatactat agctataaaa gagaaagatt acttaaaagt tgagacaaag agttttttta
      541 gttttatgca taacaattca tttaagagtt ttatttcagc actacatgat gatgaagttt
      601 tagatagtaa gagcttggac aaattagaag aatactttaa aaatttgaaa gaagaagata
      661 ttgatgacta ataaagctat cagtatcttt ttagtttgag acaattgaga gtagcgtttg
      721 gatttaatgt tagttttatg tgatggtaga acattatata aagaaaagtg attatttcct
      781 tagtgtttga tagtaaaaaa tatagagaat aataccaatt aaaatttaaa gatatatgaa
      841 atactacaat agcttaaatc atgtaaatat gataaagata ttgaaattat aaaaggaata
      901 taattttaga agaaatagtt gacagataaa ttaccttact atattattgt attaataaaa
      961 taatacaata atatagtaag gaggtaataa atgaaatcta gaaaacataa tattacaaaa
     1021 ggattattta tagtttacat aattatttta acatggataa tactatttaa gttgcaattt
     1081 gatatctcat ctcttgaaac catgaatctt agaagcataa acttaatacc ttttgctggg
     1141 tcacttataa ttaataatag agtagatata tcagagatta tattaaatgt ggctatattt
     1201 gtaccatttg ggatatatgt gtgtatgcta aaagaagaat ggagctttat aaaaaaagtt
     1261 atacctattt ttataactag tttggtattt gaaacacttc aatatatatt tgcactaggt
     1321 gcaagtgata taacggattt gataggaaac acactaggag gaatcatagg aatagctgtt
     1381 tttatgctat tatcgaaaat atttaagaat aataccataa aaattatcaa tgtattggca
     1441 ttgattgtga caattattgt tgtattattt ttaggattag ttatttttgc aaacttatag
     1501 aaataagtat atatgtttag cttaaaatag aacgtaagat acagttacat ataaaattat
     1561 ttacacataa aaagcaccta tacaggtgct ttcctaaatt attaaagaat tattgtatct
     1621 tgaaactctt gtatgttcaa ttcttgattt tctcttgttt tttctaataa atctaacgca
     1681 caatttatac aaactttaat ttctgcattg gtatttttct cataataagt tatatattta
     1741 tttctatatt tatctatttc ttttccacaa cgactacaca ttacaattac gctcatatct
     1801 tagttcctcc atctctaatt attcttaata tattcaatag tatcactttt ctgaaaataa
     1861 tgattgttaa aactgtatca aatttagatt tactttttat tataatgcat tttaataaaa
     1921 aaataaaggt tatgggtaaa atatttatag aaaaaagtat attattgaat agattataaa
     1981 attttattat tttttagcag tgttaaatac acattaatat ctataaagtg acaaaataaa
     2041 aaatactatt taaatagata ttaaaaaatt gataccaagt atttatttgc tatatgaata
     2101 acaatttatt taggaacttt actttaacac tgtataataa taaagtaatt gctaaaaacg
     2161 tttgatgatt tggatgtatt tttagaaatt agaaaaatat atacttactg actaatgata
     2221 atcttatatg tattttagtt tgagtgattt aagaaaagtg ttttgaatgg ggattatttt
     2281 atagagtaaa taaatatata atagtagaaa attacatata aagagtagtg tttatttcat
     2341 taccttcttt atctgttccg atagggtctt gtagagatac ttgagtttta ttttttttgt
     2401 tagatctaat attcattaaa atctcatttt caatacatct agaagcatat gttgctaatc
     2461 gagttccttt atctatgtta taagtttcta tagctttaat taatcctatt gtacctatgg
     2521 atattaaatc atcctgatct tccgttgaat tattatattt ctttgctata taagctacta
     2581 atctcatgtt tctttcaatt aatgtatctt ttgcactttt atcgttttct attttaaatt
     2641 tagttaaata ctcaatctct tcttcagggg ttaagggttt ttcaaaagat ttaagagctg
     2701 ccaataggtc accccctttt caacggtcac tttaaattat atgaaggaga cttatccaag
     2761 ttgactgtta tctaataaaa taatatgcat atttttagaa tttaaaacat atatttgcaa
     2821 acttttgaat ggaatatgac ataaagagtg ggaatttaaa tttaagtttt tgttgtatat
     2881 atatgaaata aggcgaagaa attattgatt tataaagtat aaattggaat tgaggtgtca
     2941 ataaatataa aaggaaatag tatttatata tgttttggtg ttgaagtaaa agattaatgc
     3001 aaagcattag agtctataaa aatatgaata taggaggtgt aattttacaa tacttaaaaa
     3061 agtaaatgta attaattgtt tgtataaagt tgattacaag caaaagtatc agtcatagtt
     3121 aatactgtta agggtgaagg tggtgtgtta atttatatat gtatgggaag aaattttgat
     3181 tacaatgaaa aaacttacaa aagatattta tgaaaaaact tatagttaaa tgtttatata
     3241 taaaatatta tttaggggtt gtttttatta ttgaaaataa gaaagagtgg ttttatatca
     3301 attgaatgta taataagtat tgctatatta tatgtggctg tttatttagt ttctacatca
     3361 ttgtataatt gttatagttt tatcagtaga aatatatctg acagagaaat gttaagtaca
     3421 gcaaaaaaat atatagaaga tgagaagtat agaatacaaa atagtaagta tgagttaatt
     3481 gaagataaga tagaaaaaaa ttacataaat ggatatgaaa ttaacagtaa aatagagcaa
     3541 attttagatt attatcaatg ctatgaaata aatatagaga taaaaaatga atttaaaaaa
     3601 ctgaggttta atagctatgt tactagaaaa taaaggctct atattaataa taacattgat
     3661 aatattttct attataagta ctgtgtgcat tatgtgtata ggtttaattt atacacataa
     3721 taatatgttt gagttaggat acaaggacat tcaactaaaa gaaatttctt taagtggaat
     3781 agaaatatca gtaagtaatg tactttcttg tgttgaggaa gctattgatg tatctaataa
     3841 tgaagacgaa tttagagaat atttcttagg aaataatatg attgaatgta taaaaaaaat
     3901 aaaagataca tcttatagta gtttagaaga actttcttta aaagtagaaa ataatactat
     3961 ttatgacaga ggagattttt ttgaatttga tatagaaagt aatgttagag aaaaagaatt
     4021 tttaaaagca ataaaagtaa gagtgaaaat caaaaatcca tggataggaa ttgacattga
     4081 agattatatg gataaatcta ataacaataa aattgatgac aaaacattca ataattataa
     4141 agcatctgaa aataatgaaa ttctaaatca atttaaaaat gaaagtgaaa atataaggaa
     4201 tcaagaggtt ggtggattta cagaagaaga tgaagaagat gaagaatatg aagaagaact
     4261 taaacaaaac ataattgaaa atataaagaa gaattttgat gaaaaaaacc tagtacaggt
     4321 atataagtat aggggtgtat aactttgaaa aaagaaggaa tgtgactgta atagaattaa
     4381 tagtatctat cagtataata ctcttgatag ttacattatc ttttccaaaa gataatcttg
     4441 aaaatcataa aataaattta tttgcacgtc aactttgttc agatataagg tatgttaggc
     4501 gaattaatat gtttagcaac tacaatacat atatatatta tataaatcaa ggtaaacacg
     4561 aaggttatgt attgagaaaa gatggtaaaa acattaaatc aataatgcta cctaaaaatg
     4621 caaaaatagc taggagtatt gaaataataa agtttaaatc tgatgggtcg cctcaaaagg
     4681 cgtctacaat agagatatat aataatagat taagaaaaac tataacaata acacctgtaa
     4741 gtggaagagt acttctgaaa gagggaaaat atgaaacata aatatggtta cttgcttttg
     4801 gaaagtgtcg tatcattgtc ttcaatggtg ataattatac tagttttata ttctatattt
     4861 ttgtctacaa taaacttaaa gttaaaagta gaagataaga tagaactaca acaacaaagt
     4921 cttgaaatca taaaatctat ggaaggaatt attagcaatt ctatgggaat aatgaatgta
     4981 tctaattatg aagaaacatt taaaaagaca acatctataa aatgtagata tttagatgaa
     5041 aataataatg aagaaggcat aagtaataaa gaaattatat tgaatgaaag acgaaataag
     5101 ttatttgtaa attctttaaa tggcgaaagt agtcaagcag gtggttatga aattggagat
     5161 tatgtagatg agatgtatgt atcaattact aataatggtc aatatgttaa tattaaattg
     5221 aaattatcaa aacgtagtca aaaatatgag actgatttca aaataaaagt atggaatttt
     5281 agtgaaagta tatagaaata cataaattta agagaaagaa gtgacatcaa taagtcatat
     5341 aaaatataat tattgagaac tatataacta aataatatca atatgtaaag tgtatagatt
     5401 aagaatatag aggataataa taaaaatata gaataagtaa tttgccaaat acttgtttat
     5461 attgtataac ttatgatatt atgatattag taaaaatttg taatcctgac ttgacagaat
     5521 tcaagtaaga gatataattt taaaggcata gtaatgtaaa atttactaaa aaataagaaa
     5581 tttattttaa tatggaggaa caaaaaatgg tatcagcagg tgattttaga aaaggtgtta
     5641 catttgaaaa agatggacaa ccatgtttag tagttgattt tcaacacgtt aagccaggta
     5701 aaggagctgc tttcgttaga actaaataca aaaacttaaa aacaggagct ataagagaag
     5761 aaagtttcaa tccaagtgaa aaattcccta aagctgttat agatacaaga caaatgcaat
     5821 atctatacaa tgatggtgag ttatattatt ttatggatca agaaaatttt gaacaaatac
     5881 cattaaacta tgagcaagtt gaagatgcaa ttaagttctt aaaagaaaat gaagttgcta
     5941 caataagatt ttaccaagga caaccattcc aagtggaagc gccaaacttt gcagagctag
     6001 aagttacaga tacagagcca ggtataaaag gtgatacagc aagtaatgta actaaagcag
     6061 ctacagttga aactggagca gttgttcaag ttccattatt tataaatact ggagataaag
     6121 taaagataga tactagaaca ggtgaatatt tatcaagagt ataaaaattt atgtatataa
     6181 aagcttatat gtcttaataa tataagatat atgagctttt agtttatata taaaaaagaa
     6241 agcgaggggt gttacatgaa acatttatat gaagaagttg catacttaaa aggcctagca
     6301 gaaggactag aaataagtgc tgaaagtaaa gaagggaaaa tgatacataa aatagttgat
     6361 gcattagaag tatttgcaga tgctattgta acattggatg aagaacaaga agaacttcaa
     6421 gattttgttg aatctataga tgaagattta gcagatttag aagaagatat tgctgacatg
     6481 gaagaagatc tttatgaaga agatgacgat gaggatgatg aggacttcag ctatatagaa
     6541 atggaatgcc caaattgtgg agagttagta gaaatagacg aagatttgtt atatgatgat
     6601 gaagtagatg ttgtttgtcc tgattgtaag gctgtgatat tatcatcaga agatgattgt
     6661 gatgatgatt gtacatgtgg tggttgttca agttgtgatg atagagagta aaaattcata
     6721 agaattaaaa ctgcctatga tgcctatgag atattttgct tcataggtag ttttattttt
     6781 atgaggaagg gtattatgta ttttggtttt gcaatacttg gacaaaaata gtacactaga
     6841 atttatagaa taggattttg gagggatgta aatatgaaaa taagtaaaaa attactagat
     6901 aatatacaaa gatttgaaaa tgttataaat tataaattta aaaataaaga atatatacta
     6961 gaagctctta ctcatagttc atattctaat gaaaataaaa aatataattt taacgaaaga
     7021 ttggaatttt taggggattc ggttttaggc atagtgataa gtgattattt atttaatgaa
     7081 gaagctaatc tgcccgaagg ggaactaact aaacttagag caaatatagt ttgtgaagat
     7141 tcattaagtg aagtagctaa tgatataaat ttaggtattc acatgttatt aggtagagga
     7201 gaagaagcaa caggaggaag acataggact tcaatattag cagacgcatt tgaagctgta
     7261 atagctgcta tatatcttga tggaggtttt gaaagtgcaa gacagtttat acttcatcat
     7321 atggaaaata taatttatga ttcaagaaaa ggaaatatat ttagagacta caaaacgcat
     7381 cttcaagagg tgttacaagg gaatggagaa aataatatct ggtacaggct tatagaagaa
     7441 aaaggaccag accataataa aagatttgta atggaagttg gaattaatga cgatgtactt
     7501 ggtataggag aaggcaagag taaaaaagaa gctgaacagt tagctgctaa aatagcttta
     7561 aagaaaaaat tatgggaaaa ataaatataa tatgtaaaaa tataaaaaga aatatttata
     7621 ttagaaggat gttgtagatg aaaaagagaa ttatacctat atttgttcct cacaaaggat
     7681 gtcctcatga ttgcatattt tgtaatcaaa aaaaaataac aggtgtgagt actgatgtta
     7741 ctagtgaaga tgcaagaaat ataattgagg aatgtttaga gactatagat aaagatgcag
     7801 atgtagaaat agcatttttt ggtggtagct ttactgctat agatattgat atacaaaaaa
     7861 gtttattatc agttgctaaa gaatatgtag aaaaaggtct tgtaaaagat attagaatgt
     7921 ctacaagacc agattgtatt gatgaagata tattaagtat gttaaaagaa tataagacaa
     7981 gtataattga actaggagta caatccttag atgaaaaagt attattagat agtataagag
     8041 gtcatcaatc tgaaattgta tacaagagtt caaagatgat aaaaaatagt ggaatcaaac
     8101 ttggattaca gatgatgatt ggtcttccag ctgacacaga agaaaagtgt atatttacag
     8161 caaaaaaatt tgtagagcta aaaccagatt gtgttagagt ctatccaact ttggtagtaa
     8221 aagatacagg tcttgaaaag ttaatggaac aaaataaata taatccattt actcttgaag
     8281 agagtgtaaa tatagtaaaa aaagttcttg tactgtttta tgttaataat atcaatgtaa
     8341 taagagttgg gcttcaagct actgatgata tacaaattgg aaaagctgtt ttagcaggac
     8401 catatcatcc tgcatttaga gagttggtag aagcagatat gataaaagat tatttagaat
     8461 ttgttatttt gcaaaataaa aatataaagc aaatgttggt caaatctaat aaaaagaata
     8521 tttctaaaat cataggaaat aaaaaaacaa atgttaaata tatggaagaa aaatttggtg
     8581 tgcttttaaa aacacaagaa tcagatttag atataaatca attagaaatt gtgttagatg
     8641 ggaaaagttt aattagtgct aatatgagag acattcatag aaaattgtat gacatttatg
     8701 acctttagtt ttaataatga agggagagaa aagatttgta tttaaaaaga ctagagttaa
     8761 agggatttaa atcctttcca gtaaaaacag atattatttt taaagaagga ataacagcca
     8821 tagtaggacc aaatgggagt ggaaaaagta atatatctga tgctgtaaga tgggtattag
     8881 gagaacagag tattaagagt cttagaggtg ataaactcga agatgtaata tttgcaggta
     8941 cagatacaaa aaaacctatg aattattgtg aagtggctct tactattgat aattctgaaa
     9001 atcaattgga attagatttt acagaagtaa ctataagaag aagggcttat agaaatggtg
     9061 aaagtgaatt ttttctaaat aataaaagtt gtagattaaa agatataaaa gaagtctttt
     9121 tagatactgg tattggaaaa gatggttatt caatcataga acaaggaaaa gtagatgaaa
     9181 tattaagtaa taatccttta agcagaagaa aagtttttga tgaagcttgt ggcatatcaa
     9241 aatatagata taaaaaacag gaagcagaaa ggaatttaag taatacaaag gaaaatttag
     9301 aaagaataga tgatgtatat atagaaattg aaaatcaatt aaagcctctt tttaatcaac
     9361 agacaaaggc aaaaaagtac ttggaaataa gtgaaaaatt aaagacactt gaagtaaata
     9421 gctttataag agaaattgaa ggaatagaaa aagaattaag tgaggttaat gaacatcgta
     9481 aggttattga aaaggagctc aatgaaaaag aagaacaaaa aaatgttgta gagaaaaagc
     9541 aagaagatat taataaagag gtagaggtat tacaagatgt aattgaaaaa tctgtagatt
     9601 atataaattc aattaaagga gttatatcaa aaaaagagtc ccaaataaat ttaattaagg
     9661 aaagaataag aaattttacg aatgaaatta gtagaaaaaa tttagaaata aaggatataa
     9721 aagagaagct aaatgaaaat aagcaataca taaaagaatt agaaagcaat aaattatcag
     9781 gtagtgaaga actatctacc ttgcaggaaa atataaaagt attggaagga agtaaagata
     9841 aacaaaaaat taagttagaa tccctaaata atgagataga attattgaaa gaaagtataa
     9901 ttgatatatt aaataagaaa caagagttta gtaataagct gtctacttta aacgcaaata
     9961 aagaaaatat gaatatcaga gatgaaaata taaattcaga gataacagag ttaaacaaaa
    10021 atattgaaat aaaatcatct gaattagata ctataaataa agaatttaat atgcaaaatg
    10081 aaaatttaaa gaatgtaaat aatagacata aagaattatc aattaatttg caggattcaa
    10141 ttagtgaaca caataaacta gaagatgaaa tacagaaaag taaatataat ttaaatggat
    10201 ataattcaaa gttaaatgtc tatatagata tggaaaatca ttatgaagga tttaatagag
    10261 gagtaaaaga agtactaaaa aataaaaatt taaaaggagt tcatggagca ttaggacaga
    10321 ttataaatgt acctgaaaag tatgagaaat ctatagaagc agctcttggt gcttatatgc
    10381 aaaatataat aactgataat gagtttagtg ctaagtttgc aataaactat ctaaaacaga
    10441 ataatttagg tagagtaaca tttcttccat taaatataat taaatcaaat aaaataagtc
    10501 taggaaattt aaaagcaaat actaagttca taggaatagc aagtgattta attacatttg
    10561 atgaaaagta tagaaatata attgaaaata tacttggaag aacaatactt ataaataata
    10621 tagatgaggg cataaaattt gcaaaagaaa ctggtcatag gtttaaaata gtaactttag
    10681 atggtgaaat cttaaatcca ggaggttctt tgactggggg aagtctaaaa actaatggga
    10741 atatactatc gagaaaaaga tacattaatg aatatacaga aaagataagt aatatcaaga
    10801 atgaaatttc acatctagaa ttaaaaagag aatctttaga caaagatgtg aaaaatatca
    10861 aaaatgaaat tgattcacat gaaagtaaaa taaaagattt agaaaaaagt ataataataa
    10921 aaagtacaag tataaagaat gttgagtctg aaattgaatc gttaaaaggt agtattacta
    10981 aattagaaaa tgagaagaat gatttaaatt ctaacctaaa ttatacactt gaaaaaagtg
    11041 atgatgttag aaaagatatg gaagagttag atgatttata caataaaaat aaagaaaaaa
    11101 ttgatgcatt gaatgaggaa ataaaaagat acaatgattt atatgataaa gaaaaatctg
    11161 aatttgatga attgaactta agtttagtga agaaaacaga agtttacaat agtatagtta
    11221 gagatataaa aagaatatct ggtgaaaatt gtgagctaga agaaaaaaat aaacaattag
    11281 aagagtcatt aaattatgaa gaacatgaaa taattaaatt acaagattct atactcactg
    11341 aagaaaaaga aaaagaaaat ttaacaaaac aactagggga tagtaataga aatcttgaaa
    11401 ctagaaaaat agcaaaagat gatttaaaaa atagttttga tgaaattaat aaagaattaa
    11461 aaactataga tagacagcat atagaactta aagaaagttt atttaaagtt ggtggaagat
    11521 tagaaagatt aaaaactagt caagacacat atataaataa gttgtttgag caatatgata
    11581 tgaccttagt acaagcattg gaaattaaag atgaagattt ggatatagat agaaaattct
    11641 tagaaagtct aaagagagaa ataagaagtc ttggaaatat aaatatagac tctataaagg
    11701 aatatgagga aataaaagaa agatacgatt tttatagcga acaaaagcaa gatttagaag
    11761 agtctatgga agagatagaa aaacttatac atactttaga agaaaatatg aaatctgaat
    11821 ttgaaattaa gtttgaagaa ataagtaaaa attttaaata tgtatataag agattatttg
    11881 gtggaggttg tggagaatta actattttag ataaagaaaa tttattagaa agtgatatac
    11941 taataacagc tcaaccccca ggtaaaaaaa tgaaaaattt aaacctatta tctggtggag
    12001 agaaagcttt aacggcaata agtatattat ttgctatatt gattacaaag ccaacaccat
    12061 tttgtatatt agatgagatt gaagcgccac ttgatgacgc aaatatattt agatttggag
    12121 aatttttgaa ggatttatct aaagagactc aatttatatc agtaactcat aggagaggaa
    12181 caatggaagc tgctgattat atctacggag ttacaatgca agaaaaagcc atttcaaaag
    12241 ttattagttt aaaattaaaa gaagctcagg aaataacaga tattatataa cttagattga
    12301 cataggagga ataacagtgt taaaaaaatt atttggtttt ggaaaagaca aggaaaagga
    12361 aatagaaaaa aaagatgctg aagaagaaat agaagttgaa gacagtgttg ataatttaga
    12421 aaacttggaa gaaactattt tttcaggact tgaagaagaa gtgatagata aagtggaaga
    12481 tattgaagaa aaaaatgagg aaagtgtcaa taatgaaggc actgaagaaa tcgaaaactt
    12541 tgaaaaaata gaagttgaga tggatagtaa tggaaaagaa gtagaaaata tttcaaataa
    12601 tgattctcaa gaagagataa tcgaagaatt agaaaattat gatgaaattg agtctaaaga
    12661 gatagaagat aaagaagata agaaagttaa cttgtttgaa agactaaaac aaggattgac
    12721 aaaagcaaag caaggaataa ctgatagaat agatgaagtt ttaaaatcat atacaaaaat
    12781 agatgaagaa ttacttgaag atttagagga aattttaata acagcagatg ttggtgtaaa
    12841 tacaactatg gatataattg aaagactaag agataaaata aagcaaaaag gtattactga
    12901 accaataaag gtaagagaag aacttaaatc tatagttgaa gatattctta caaatgaaaa
    12961 ctctacacta gatatagaac cagcaccatg tataatatta atggtgggtg taaatggggt
    13021 cggtaagact actacaatag gtaaactagc aaatagatac aaaaaagatg gtaaaaaagt
    13081 tttattagca gcagcagata catttagagc agcagcgaca gagcaattag aaatttgggc
    13141 aaatagaacc aatgtagaca taataaaaca tcaagaggga gcagaccctg gagctgtagt
    13201 atttgatgct ataaaagctg caaaagctag aaaaacagat gtattaatat gtgatacagc
    13261 aggaagatta cacaataagg ctaatcttat gaatgaactt ggaaaagtat ttaaaatagt
    13321 agatagagaa tttccagaag caaaacgtga agtacttctt gtggtggatg ctacaacagg
    13381 tcaaaatgca gttgttcaag caaagacatt taaagaagtt gcagatataa caggtatagt
    13441 acttacaaaa cttgatggaa ctgcaaaagg tggagtagtc cttgcagtaa aatcagaagt
    13501 agatgtacct gtaaaactta ttggagttgg agaaagtgta gaagacctac aagatttcaa
    13561 tgcaaaatca ttttcagatg cattatttgg taactaatgt tcttttaaaa ataatggttg
    13621 acaagagtgt tgttatgata taaaatacaa tagtgtaaag taaataacct ttacagtata
    13681 ctgctaggaa gtgtaagata tgaatataga aaaaatggtc gaaattggat tgttatttga
    13741 acagtataaa gaattattaa ctgacaagca gaaagaaata gttgctctat actatgaaga
    13801 agattattct ttaggtgaaa ttagtgaaaa tctgaatgta tcaagacaag gtgtttatga
    13861 taccttaaag cgttcagaaa aaatactaag agattatgaa gaaaagttac acttagtatc
    13921 aaagattcaa gagcaggaaa aaaatattaa gattataaaa gataaaatta ttgacattaa
    13981 agaagattta ttgcacaata gagattgtgc taatttaatc cctaagctag aaaatataga
    14041 agatgtatgt agggagatga taaaatgata tttgaaggat tgtctgataa actacaaggg
    14101 gcatttagta agttaaaatc taaaggaaaa cttacagaag tagatgtaaa aaatgctatg
    14161 agagaagtta aacttgctct tcttgaggca gatgttaact ttaaagtagt taaagatttc
    14221 ataaaaaaag ttcaagagag atgtgttggg caagaagtta tgcaaagctt aactccagct
    14281 cagcatgtaa tcaaaattgt aaatgaagag cttacaagtt taatgggaga tgtacaaagt
    14341 aaagtaatga tttcctcaaa gcctcctaca attttaatga tggttggatt gcaaggtgca
    14401 ggtaagacta ctacagcagg aaaacttgga ggatatttta aaaagcaagg taaaaaacct
    14461 ctattagtag cttgtgatat ttatagacca gcagctataa agcaacttca agttgttgga
    14521 gaaaaattgg atatacctgt attcaatatg ggagataaag aaaatccaat aaatattgcg
    14581 aaagcaggtt taagccatgc gattaaaaat gctaatgatt tagttattat agatacagct
    14641 ggtagacttc atatagatga agtacttatg gatgagttaa agtctattaa atcagaagtt
    14701 aagccacatg agatactttt ggttgtagat tctatgacag gtcaagatgc tgtaaatgtt
    14761 gcagaaagct tcaatgaggc acttggtgtt gatggagtag tattaactaa attggatgga
    14821 gatactagag gtggtgctgc gctttcaata agagcagtta cacaaaagcc tataaaattt
    14881 atggggatgg gagaaaagct agatgatata gaacctttcc acccagatag aatggcatca
    14941 agaatattag gtatgggaga tgtcttaagt ttaatagaaa aagcacaaga aaatatagac
    15001 ttagagaaag ctaaagaatt agagcaaaaa attaaaaaac aagagcttga ttttgaagat
    15061 ttcttacaac aaatggaaca aatacaaaat atgggacctc ttgacaagat acttggtatg
    15121 atacctggta tgggaaatgt aaaagaccaa cttggagatg tagatttgaa tggcaaagaa
    15181 atgaagagaa caaaagccat aattcagtca atgactacat atgagagaag aaacccagga
    15241 gtattaaatg cttcaagaaa gaaaagaata gctaaaggca gtggaactag tgtacaagat
    15301 gtaaatagac ttataaaaca acttaatgaa atgaaaaaaa tgatgaagat gtttgctggt
    15361 tcacaaaaga gtatgaagaa aaggggcggc ttaggcggtt tacctttttt taaataaaat
    15421 ataaaaaagt aaaaattatt cggaggtgac tgtaatggca gttaaaataa gattaaaaag
    15481 aatgggagct aacaaaaaac ctttctacag aatagtagta gctgattcaa gagctccaag
    15541 agatggaaaa tttatagaag aaataggata ctataatcca atttctgaac ctaaacaagt
    15601 aagaataaat gatgaaaaag ctataaaatg gttagctact ggtgctcagc caacagaagt
    15661 agttaaaaaa ttacttgtaa aaaacggagt aatagaaaaa ttcgaagctt ctaaacaagc
    15721 aaaataattt tttcttggca attagtttaa gtaagggctc attgctaagg ttactttagg
    15781 agatgaaata tatgaaagag ctagttgtag atatagctaa ggctctagtt gataatcctg
    15841 actcagttgt tgttgaggaa tttgaagata atgatggtat cgtcttaaag cttacagttg
    15901 ctcaagagga tatgggtaag gttattggga agcagggaag aatagctaaa gctataagaa
    15961 ctgtcgtaag atctgttgca aatagagaaa atataaaagt ttctcttgag atagtataaa
    16021 ataggaggat taggtataat gcctagtcct ttttatataa atgcgtagtt taagatttta
    16081 tgatgatatg accacataag attaaatttt ttaagaaggt gataacatga aagaaaaatt
    16141 aactcatttt aaggtaggtc aaatagtaaa tacacaaggt ttaaaaggtg aagtaagagt
    16201 ttatccgctt actgatgata tagagaggtt tgatgaatta aaagatttct atctgggaaa
    16261 agatttaaat aataaattgg ctgttgaaaa agtaagatac aaaggttcta tggttataat
    16321 gaagataaaa ggcatagaca gcatagagaa agcagaaaaa ctaaaaaata aatttatgta
    16381 tgtagctaga gaagatagca gagagcttga agaaggcgaa ttttttatag cagatatgat
    16441 tggaatggaa gttttaactg tagatggaaa atatgtaggg atactagaag atgttcttca
    16501 atactcagca aatgatgtct atgtagtaaa aggtgaggaa gataaagaat ttatgatacc
    16561 agctataaaa aaatttgtac ctacaataga tattgatgaa agaaaaatga ttatagaccc
    16621 tattaaggga atgatagatt aggtggtaat atgagatttc atataatgac actttttcca
    16681 gaaatattta attcgtacat ggatgaaagt ataatgaaga gagcagttga aaaaggtata
    16741 attgaggttc atatatataa tataagggat ttttctaata ataaacataa aaaagtagat
    16801 gattatccat ttggaggagg agcggggatg gtaatgactc ctcaacctat atatgacaca
    16861 tataagcata taataacaac tcataatata aataacccaa gtgtaattta tcttactcca
    16921 aaaggtaagg tatacaatca atctatggca aagcagatgt ctttaaaaga agatataata
    16981 ctactatgtg gtcattatga aggaatagat gagagaatca ttgatttaat agttactgat
    17041 gaaatttcaa ttggagatta tgtattaact gggggagagc tcccagcact tataatgata
    17101 gattctatat cgagattaat accaggtgta ttaaaccaag aagaatcatt tgaagaagaa
    17161 tcatttaaag acaacttatt ggaatatcct cattacacta gacctagaga ttttgaagga
    17221 ttaaaagtac cagaagtgct tttatcaggg aatcataaga agatagatga gtggagaaga
    17281 gaagaatcta taaggataac caaagaaaga cgatttgatt tatataaaaa atctaatgaa
    17341 aaataaaaat ataatgaaaa attaatatat atgtatacaa taaagtacct ataaatggaa
    17401 ttaaaaacat aaaagtgctt gtaataacta ttgaagtata gtataatata aaatgttgaa
    17461 aatacgggcg ttcctctgtt tacactggtc gggtagttaa gaacgtctat gatatctagg
    17521 aggaagaaag atgaatgaaa tgctaagagc aattgagcaa gaacaattaa aaaatgaagt
    17581 tcctaatttt ggacctgggg acacagttaa agtacacgtt agaattatag aaggaaaaag
    17641 agaaagaata caagtattcg aaggtgtagt attaaagaga caaggtggag gagcaagaga
    17701 aactttcaca gttagaaaaa tgtctttcaa tgttggtgta gaaagaactt tcccagttca
    17761 ctctccaaaa atagaaaaaa tagaagttac tagaaaaggt aaagtaagaa gagctaaact
    17821 aaactactta agaggtagag taggtaaagc tgctaagata aaagaagcta gaaataaata
    17881 attaaaaact ttacttataa atggggggct gatttatcag tcctctttct attttaatga
    17941 aaattacagc aaataattat actagaaata aatagaaata tttgttgaaa atatacatta
    18001 tttatctatg aatttatagc ttttaaaatg aaaaataaaa ttggtaaata ttgcattata
    18061 ttttgtaaca atattaaaaa taagagaaca gtattatgta aagtatgacg ttaaaaagat
    18121 gacaatatta tagtttgtta agatagattt tttaagtgga attaggatat aataatataa
    18181 tattaataag gagtgataca tgtgtcaaat gaatacgaag agtatcttat gaatgacaat
    18241 ctacatataa actggtatcc aggtcatatg aaaaaaacta aggagttagt aaaaaataac
    18301 ttaaaattga ttgatgtagt aattgaactt ttggatgcta gaatcccgtt tagtagtaaa
    18361 aatccagaca tagacaggct tgtaggagat aagccaagag ttgtcgtact taataagagt
    18421 gatatggcag atagggataa attgaatcaa tggattgaat actataagaa aattaatatc
    18481 aaagctatac cagtagatac aataaaaggc gttggtataa ataagataat cgaagaatgt
    18541 aaaaatgtaa ctagagaaaa aatgagttct ttaaaagaca aagggagaaa agaaagagct
    18601 atacgaataa tgatagttgg agttccaaac gttggtaaat cgtctcttat aaacaaatta
    18661 acaggtagaa aaagcactca aactggagat aagccaggag taacgaaagg gaaacaatgg
    18721 gttagattaa agggaaatct tgaactttta gatacacctg gaatactttg gcctaagttt
    18781 gaagaccaag aagttgcatt aaatttagca tttagtagag ctataaagga tgagatttta
    18841 gatactgaaa ctttggcttt aagacttata gagaaactta tgaaaataga acctgagaag
    18901 ttgaaagcca gatataagtt agattgtcta ggagaaactc caattgaaac tatggatatg
    18961 attggccata aaagagggtt tataacaggt aaaaaagaac tagattatac acgcatagcc
    19021 acaactgtat taaatgaatt tagagatgga aaaataggaa atataacatt ggaagttcca
    19081 gaaaacgtta aaagatagat tttaaaacaa aatcaaaaat ttaatgttaa aaatttaaaa
    19141 aagcctttta gcaaaggctt ttttattttt ttgaaatata gacaaatatc tccatataaa
    19201 agtataaatt aggttagaaa acctttaaaa atattaattt aagacaaata tacctaatat
    19261 tttgaaaatt aaaatgagtg tgattattta aaattttagc atattgactt gcttgtttcg
    19321 tataatatat aataagcaca aataaataca atatattaaa aatttaattt atttaatttt
    19381 attaatttaa taataagttc ttattgttta attcaactta cttatgcaag cgtaaacaat
    19441 cgagacattt tattaattta ataaggttaa aaagggggat tttataatgg gtaagaccaa
    19501 ggatgttata gtatttggat ttgcgttatt tgcaatgttc tttggagcag gtaacttaat
    19561 atttccacct tacttgggaa taattacagg tccagaatgg ttaattgcct tcttaggatt
    19621 tacgtttgct gatgctggat tggcacttct agcagtaatg gctacagcta aattcgatgg
    19681 aaacgtagtt gaaatgttta aaagatgtgg tatgaagtta ggaattctta taggttgtgc
    19741 agatatttta tgtataggac cattcttagc tataccaaga acaggtgcaa caacttatga
    19801 aatgggtata atgcctttgt ttggaacttc aattccagtg ttattattct gtatactttt
    19861 ttttgcgatt tcatatgtac taacaataag accttctaag gtcgtagata tagttggaca
    19921 gtttttaact ccagctcttc taatagcttt agcatttata attataaaag gtattatatc
    19981 acctcttgga gatatagtag ataaacctat gatacctaat gtatttgcag aaggtatagg
    20041 tcaaggatat cagacaatgg atgcttttgc agcaatagca cttgcatcag tgctaatagt
    20101 atctttaaat gataaaggat attctactat tagtgacaag ttgaaaatga ttggtaaggc
    20161 gggtgttctt gcttgtggag gattagctct agtttatgga ggattatgtt tccttggggc
    20221 aactgtatca acaatgtatg gaacagatgc agtacaatca caagtaatag taaatataac
    20281 tgaaggattg cttggaaatg ttgggaaagc gattttagca gtagtagtat cattagcatg
    20341 tttaactaca tctataggtc ttacatctgc cacaggtcaa tatttctcta gacttacaaa
    20401 aggtaaattg agttatgaaa aaatagtatt agctgtatct gtattcagtg cagtagtagc
    20461 atcttttggt gttggaacta taataaagat agcatctcct atactaagta tagtttatcc
    20521 accatcaatt gttttaataa ttttagcttt cttcaatgaa aaaattaaga atgataatgt
    20581 atacaaagga gcagtatata tgtcattgtt tgtaagtata ctaacagtta tatctagtta
    20641 tggagtagct gttccagtag taaattcttt acctcttaat tcattaggat ttaactgggt
    20701 ggtgccagtt ataatagctg gaataattgg taattttata ccatcaaaga gtcaatctaa
    20761 tacacttgga acaaactaag ttttgtttaa ttaaaatata atcaattgta aataaatgag
    20821 ttaactaaaa gtaaaaggag ttatttgtac aaataactcc ttttatttt
//
LOCUS       DAMJWC010000063        20740 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMJWC010000063 DAMJWC010000000
VERSION     DAMJWC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.063"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            54..1010
                     /locus_tag="PC503_002834"
     CDS             54..1010
                     /locus_tag="PC503_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF2528800.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1187..1342
                     /locus_tag="PC503_002835"
     CDS             1187..1342
                     /locus_tag="PC503_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528801.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            1472..2485
                     /gene="aroF"
                     /locus_tag="PC503_002836"
     CDS             1472..2485
                     /gene="aroF"
                     /locus_tag="PC503_002836"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2528802.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2507..3571
                     /locus_tag="PC503_002837"
     CDS             2507..3571
                     /locus_tag="PC503_002837"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF2528803.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3571..4884
                     /gene="aroA"
                     /locus_tag="PC503_002838"
     CDS             3571..4884
                     /gene="aroA"
                     /locus_tag="PC503_002838"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF2528804.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4862..5941
                     /gene="aroC"
                     /locus_tag="PC503_002839"
     CDS             4862..5941
                     /gene="aroC"
                     /locus_tag="PC503_002839"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF2528805.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            5944..7140
                     /gene="pheA"
                     /locus_tag="PC503_002840"
     CDS             5944..7140
                     /gene="pheA"
                     /locus_tag="PC503_002840"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF2528806.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFSGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSKFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7187..7996
                     /gene="aroE"
                     /locus_tag="PC503_002841"
     CDS             7187..7996
                     /gene="aroE"
                     /locus_tag="PC503_002841"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2528807.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8008..8541
                     /locus_tag="PC503_002842"
     CDS             8008..8541
                     /locus_tag="PC503_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF2528808.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            8562..9401
                     /locus_tag="PC503_002843"
     CDS             8562..9401
                     /locus_tag="PC503_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF2528809.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9669..11150
                     /locus_tag="PC503_002844"
     CDS             9669..11150
                     /locus_tag="PC503_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2528810.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11183..14617
                     /locus_tag="PC503_002845"
     CDS             11183..14617
                     /locus_tag="PC503_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2528811.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDGIEKGIWILNDI
                     TDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNVP
                     YSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDED
                     GNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESWQ
                     KPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRRM
                     NQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYNK
                     GTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPIF
                     RKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGIS
                     FVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADKC
                     EKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDRP
                     CNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14635..15381
                     /locus_tag="PC503_002846"
     CDS             14635..15381
                     /locus_tag="PC503_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF2528812.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15330..15638)
                     /locus_tag="PC503_002847"
     CDS             complement(15330..15638)
                     /locus_tag="PC503_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2528813.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            16442..20572
                     /locus_tag="PC503_002848"
     CDS             16442..20572
                     /locus_tag="PC503_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2528814.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTSPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINPDNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWTGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNIST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEIT
                     STTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDFWC"
BASE COUNT         8447 a         2261 c         3450 g         6582 t
ORIGIN      
        1 gtaaggatta taaaaaattt ttagaatgta aattgaaatt taggagtaga tgtatgtata
       61 tactgaattt aaatacaaga gagactattg aagattttag agataaattt tatgtagcag
      121 aaaattctta tcttatatta agtgctccaa aaaatttaaa attgcttaag gaaactttgg
      181 atatagatga aataactttt aatgattgtc ttaaatttga tgaaataacc aaacttgatt
      241 tatttgataa ttacgatttt ttaagcctaa atacatttga actaagagat ggagaagctg
      301 ttatagaaga ggtaaatatg tatttatcag ataattttat attggttgta gtgaatgaag
      361 aacacttttt atttgaattt gtaaaaaata ttattttgaa gaactctcaa cttgaaaaaa
      421 atccagttat taatctattt aagataaact acttgattct tagagaagtt ataaaaaatg
      481 gttttgagtc tttggaaaaa gttgaagagt taattcttca aatagaagat gaaatgatgg
      541 acaacattaa taagaatcat gtatctagaa taagtgatgt aagaggatta acaagaatta
      601 tagttaagaa tactagacct cttttgtata ttggggatag aatagttaag gaaaatataa
      661 gatatttaaa atattcaaat gtaaaaaaat ataatttaga aaattttcaa ggtatagatt
      721 ttggaattga caaattatac aatttcgcat tgtcaacacg agagttagca gataaattat
      781 tagatattta ttcttccaga gtaggtgaga aaacaaataa cttaattaca aaattaacct
      841 tgttaacagc catatcagca ccacttacaa ttataactgg tatatatgga atgaacttta
      901 gatatatgcc agaattaaac tggatttatg gatatccagc aactttattt tttatgctat
      961 gtataatttt tgttggaatt ataatattta aaataaaaaa attattgtaa attacagatg
     1021 atgtttaatt gattttataa aaatacatca attgagaagc tgatttaagt aaataaaaaa
     1081 atattttaaa ttgaaaatat ttatagaaaa tattgacaat tatattttct ttgttataat
     1141 tattaaacaa gaagaataat aaattataaa aatggaggat aatactatga aaggaatatt
     1201 aaaagaacta acagcaaaac tttatagctt tttttacttt atgttctggg gcttttattt
     1261 tagcgctggc tatttctttt acaaaaatat atgtacttcc tttctggtga ggccttattt
     1321 tagtgatttt gagcataagt aaattttata aaaatgatta ttttatatat ttatataaga
     1381 tttagtgctt gatagattat tttagagaac tcattagtga gttctctttt ttattttaaa
     1441 tataaaatta taatattggg aggtagtaaa aatgatagta gtattaaaaa tgggagcaga
     1501 taaaaatgaa gttaaaaaat taattgaggc tattgggaga gaaggagtag aagttaatcc
     1561 catagatgga acagaattaa ctgttttagg tttagttgga gatactagta aaatagatgc
     1621 caaaagaata gaagcaaata aggtagttga aaaagttatg catgtggtag agccttttaa
     1681 aaaggccaat agaaaatttc atccagaacc ttcaatcata aatgttaatg gaatggaaat
     1741 tggttcaaag aaaattgcta tgatagctgg gccttgttct gttgaaacag aagaccaaat
     1801 agtatctata gctaaagatg tgaaaaaatc aggtgcagga tttttgagag gtggagcatt
     1861 caaaccaaga acatcaccat acgctttcca aggattgaaa tatgatggat tggatttatt
     1921 aaaaaaagca aaagaaaaaa cagggcttcc tatagttaca gaaataatgt caacacaaga
     1981 tatagatata tttgaagaaa atgtagatgt aattcaagtt ggagctagaa acatgcaaaa
     2041 ctttgattta ttaaaagaat taggtaaaac aaataaaaca atacttttaa aaagaggatt
     2101 atctgctaca attgaagagt ggctaatgtc agcagagtat ataatggctg gaggaaatga
     2161 aaatgtagtt ctttgtgaaa gaggtataag aacttttgaa acatatacta gaaatacttt
     2221 ggatttaagt gcaattttag ctgtgaagaa acttagtcat ttaccagtta tagttgaccc
     2281 aagtcatgca gcaggtaaat catggatggt tgactcttta tctaaggcag caattgcagt
     2341 tggagcagat ggtctaataa tagaagttca taatgaccca gcacatgcac tttgtgatgg
     2401 aaaacaatcg attaagccaa atgaatatga tgaattgata agtgaattaa agactatcgc
     2461 atcagcagtt ggtagagaaa tataatctat aaaaggatgg ttaaacgtgg aagaaaaact
     2521 attagtaaat ttaaaagaaa atagctacaa tatatttatt aaaaaaaata tactaaagaa
     2581 tataggagaa gaaataaaaa aaatatattt tggaaataag atttttattg taactgatga
     2641 aaatatagca aaattatact tggataaagt aaaaaataat ttaagtgaat ctggatttga
     2701 aattaaatct ttaatattaa aatctggtga agaaacaaaa tcatttaata ctcttcctaa
     2761 aatatacgat agtttacttg actttaagtt aactagaaaa gatttgatta ttactttagg
     2821 aggaggggta ataggtgatt taggtggatt tgcagcagca acttttttaa gaggtataag
     2881 ttttattcaa attccaacat ctttattagc acaagttgat agttctgtag gtggaaaagt
     2941 tggagttgac cttgagagag gcaaaaactt agtgggaagc ttttaccaac caaaggctgt
     3001 gtttatcgac ccaaatgtat tattatcact tccagaaaaa ttctatagag atggaatggc
     3061 agaagttata aaatatggat gtataaaaga caaaactttt ttcaataaac ttttaagttt
     3121 aaaaaataga gaagaagtaa tgcaacatat agaatacatt atacataaat gttgctttat
     3181 taaaaaaact gtagttgaag ctgatgaaaa agactttgga gatagaatgc ttctaaactt
     3241 tggccataca ttaggtcatg ctattgagaa atactacaat tttacaggtt atacccatgg
     3301 agaagctgtt gccataggaa tgtataagat aactttagaa agtgaaaaga taggaattac
     3361 aaaaaaaggt acatcagaac ttataaaatc aattttaatg aattataatt tgccttatga
     3421 gattgaatta agagataata aatctatagt agatgctata tctcttgata aaaaaaatct
     3481 aggtgataca ttaaaaataa tacttttaaa agatattgga gagagtatta tatataatac
     3541 tacttctaaa ttttttcagg aggtaagata atgggaagtc taaaaatata tccaagtaaa
     3601 ttatctggag atgtaaaaat accaccatca aaaagtatgg cacatagggc agttatttgt
     3661 tcatctctaa gcaatggaaa aagtagaatt tctaatatag atttttctga tgatataata
     3721 gctactataa gagcaatgac atcattagga gctattatag aaaagaaaga agatatttta
     3781 gaaatttcgg gaattttttc taaagaaggt attttaaata gagagaatca gttgaatcaa
     3841 cctaaattga caatagattg taatgaatca ggctctacat tgagattttt agtacctata
     3901 tctttaacat ttgatggtgt aaaaaggttt ataggtagag gtaatcttgg aaaaagacca
     3961 cttgatacct attatgagat atttgacaga cagaatataa aatatagtta caaagaaaat
     4021 cagttagatt tgattatatc aggtaagctt aaaccagatg aatttagagt aaaaggaaat
     4081 ataagttctc agtttatcac aggtttactg tttatattgc ctacgctaga aagtgattca
     4141 aagataataa ttactactga gctagaatct aaaggatatt tagatttaac tctttcaacg
     4201 ataaaagatt ttggggtaga aattataaac aataactata aagaatttat tataaaagga
     4261 aatcaaacgt ataaagcgag agattataaa gtagaaggag attattctca aggagcattt
     4321 tatttatcag cagatgctat aggagaagat attagcatat tagaccttaa agaagattct
     4381 cttcaagggg atagtgaagt agttgaaatt ttatctagga tgggaatgga aatattaaga
     4441 gaaggcaaca aaataaaagg aataacaaat ggtttaaatg gtactttgat agatgcatct
     4501 caatgcccag atataatacc tgtattatct gtagtagcat ccttaagtat agggaggact
     4561 acaataatta atgctggtag gcttagaatt aaagaatgtg atagacttca tgcaataaat
     4621 gttgagttaa gtaaacttgg agcaaatata gaggagaaag aggatagttt gataatcgaa
     4681 ggagtaagca agttaaatgg tggagtagag gtgtggagtc acaaagacca tagaattgct
     4741 atgacacttg caattgcttc ttgtagatgt gataaaccaa taatattaaa agattttgag
     4801 tgtgtatcaa aatcttatcc acattttttt aaagatttta agatgttagg aggtcgaatt
     4861 gatgagtgga atatggggaa ataatttaaa agtatcaatt tttggagaat ctcatggaaa
     4921 tgctataggt ataaatatag atggtcttcc ttcggggatt gaacttgacc ttgataatat
     4981 tgataaagaa atgaagagaa gagcacctgg aaaaaattct atatctactt caagaaatga
     5041 aagtgatata ccagaaattc taagtggata ttttaatgga agaactacag gaacgccatt
     5101 atgtgcaatc ataagaaata gtgatactcg ttcaaaagat tatggagagc ttaaaaattt
     5161 aatgagacca ggacatgcag atttcacagg taatgtgaga tattctggat ttaatgacta
     5221 tagaggggga ggtcattttt caggtaggat aacagctcca ttagtatttt gtggggctat
     5281 atgtaaacaa attttatcac aaaaaggaat agagatagga gcacacataa aaaaaattaa
     5341 aaatatagaa gatatgagtt ttgattatgt aaatatttca aaacaacagt tatcaaattt
     5401 gcaaactttg gaactacctt tacttgattt atcaaaggaa gaagccatga aaaatacgat
     5461 tatagatgca aaaaatcaag gagattcagt tggtggtata attgagtgtg cagtagtagg
     5521 tattaatgta gggcttggaa atccattttt tgactctgtt gaatctactt tatcacattt
     5581 attgttttct gttcctgctg taaaaggtgt agagtttggt ttaggttttg aacttgcaga
     5641 tatgtatggg tctcaaagta atgatgaaat gtattatgaa ggaaatcaag ttaagagcaa
     5701 aacaaataac aatggaggaa ttataggagg gattactact ggaatgccaa taattttcaa
     5761 agtggcaatt aagccaactc catcaattag cagacaacaa aacacagtta atataaaaga
     5821 taaaaaggac gatattttat atattaaagg tagacatgac ccttgtatag ttcaaagggc
     5881 tatacctgta atagaagcag taacagccat tggaattttt gatttgatga aaggacgata
     5941 ataatggagg atttaacgag atatagaaat gagattgaca atatagataa agagcttatt
     6001 caattatttg aaaagagaat gaatacagtt cttgaaattg ccagacataa aatgaaaaat
     6061 aacactacta tacttcaaaa agatagagaa gaaaaagtac taagtagagc tgtagataat
     6121 ttagataata aagcatattc acaagaaacg gtacagtttt ttaattctat aatggaaatt
     6181 agtagaggat tacaaaaaag attgatagat aatgatggtg agcagaaaat cgagtttagt
     6241 ttagattcat caaataagaa atttgatttg tcaaatgtaa atagatataa gtctttaaaa
     6301 gatgaattaa ataaaaaaaa tatcctagta ggattttcag gaaaatcagg ttcatttaca
     6361 gaagaagcac taaataaatt cttcaacaaa aaaatatcaa aaaaacaatt taaagaattt
     6421 gaagatgttt tcatagcact taaaaataaa gaaataaact atggaataat ccccatagaa
     6481 aattcatcta caggagctat ctctgaaact tatgaccttt tgagaaagta cggtttttat
     6541 atagttggag aagaatgtat aaaaatagac caaaatttaa tagggataaa agacacaaag
     6601 cttgaagata taaaagaaat atattctcat ccacaaggta taggacaatg tagtaaattt
     6661 ttaaaacaaa atagtacatg gaaattgata ccatttaata acacagcaac aagtgcagaa
     6721 cttgtaagaa aacttcaaga taaaacaaaa gcagcaattg caagcaaaaa agctgcaagt
     6781 atttatggat tagaaataat aagtccttgt ataaatgata ttgcaaacaa ctatacaaga
     6841 tttgtagtaa tcagtaatca aatacacatt gaagaagaat caaacaaaat gagtgtagta
     6901 ttttctgttg aacatgaagc aggaaaactt tataaagtac ttggatactt tgctaaaaat
     6961 aatataaata tgacaaaaat agaatcaaga cctatgaaaa atgcctcatg gagatatttc
     7021 ttttatatag attttgagtg ttctatatac aatgctaaag tgtacgattt attagaattg
     7081 atagaacata atacagcata ttttaaattt atgggagtat ataaaaataa aactgaatag
     7141 ataagataaa tttttattta atttataatt attaggaggt gtaagtatga attttttcgg
     7201 tctagtaggt gaaaaactct ctcacagtgt ttcacctcaa atccacaaga gagtattcga
     7261 gatattgaat attgaaagtg cttataaaaa ctttgaaatt tcaaaagaag atatatctaa
     7321 gctagacggt gctataaaat tattaggaat acaaggggta aatgttactg taccatataa
     7381 ggagcgtatt atgaaatatc ttgattttat atcaccagag gcaaaacgta taggagcagt
     7441 taatacaatt ttacttagag aaaatatgtt atatggttac aatacagatt actttggtct
     7501 tgatagtatg tttaaaatgg ctaatattga tgttcaagga aaagtagcag ttatattagg
     7561 aactggaggt gcttctaaag ctgctcttac atattttatt gattctggta tagaaaagct
     7621 ttatgtttca actagaaaaa aggatgataa aaaattatta aatagtaaag ctatattaat
     7681 agattatgaa gaacttaaac atataaaagg agatataata ttaaatgcta caccagtagg
     7741 tatgtaccct aatgtaggaa tttcaccagt gtcaaaatct attatacaaa attttgatat
     7801 attaatagat ttaatttaca atcctggaga aacagagttt ttaagaattg gtaatagtat
     7861 gggtaaaaaa acttgtgatg gattatatat gctggtgggg caagcaataa aatctcagga
     7921 aatttggcaa gatactaaaa tagataatag tattttagat gttatatata atgaactaaa
     7981 attagaattt ttgtaaggga gattgttatg ataaataaaa caaaagaaaa attgatatta
     8041 ataggtatgc caggtagtgg aaaaactaca attggtaaac ttttggccaa agaatataat
     8101 tgtagtttct gtgatatgga tgattatata attcaaatat ctcaaaaaag tatagcagag
     8161 ttgttttcag aaggagaaga tatctttagg aactatgaga ctcaagcatg tagagaactt
     8221 tctataagtg ataaaacagt gatatctaca ggtggaggtg taataaaaaa ggatgttaat
     8281 atggaaatac taaaagaaac aggtataata atttttattg atagacctat acaaaagatt
     8341 ttggaagata taaatattaa ttcaagacca ttattaaaaa acggaaaaga tagattgtat
     8401 aatctttata atgagagaat aaatctttat aaaaaatttt cagatataga gattttaaat
     8461 gataaatcat taaataatgc tgtatataat attacaaatg cagtcagtga aaattttaaa
     8521 tttgacttta aagaaaaata atctaggggg aaataaaaat aatgaatatt gttattgtag
     8581 gactaggagt tataggaggc tcttttgcta aagcattaaa aaaagctgga tatgaaaatg
     8641 tatttggagt agatgtagat ttagaaactt taaaaaaagc agaaaaagca aaaatcataa
     8701 aaaaaggatg tactacaggt aaagagttat ttaaaaaagc tgatttaatt atattatcta
     8761 tatatcctag attagttgta gattttctaa ataataataa aaactttttt aaaaaaggga
     8821 ctataattac tgatactaca ggaataaaag aaacacttat caatgatgtg ttgcaaatta
     8881 ttccagatga tatagatttt atatttggac atccaatggc aggtagggaa aaaaagggta
     8941 ttgattttgc aagtgaacaa gtttttaatg gcgcaaatta tataattact ccaactggca
     9001 gaaacaacat aaaaaattta gagttagttg aaaatttaat tttagagatt ggatttaaaa
     9061 gagtaaaaaa gttaacttca caaaaacatg atgagattat agcttttact tctcagttac
     9121 ctcatgttat ggcagttgct cttataaata gtgatgaaga aggtagagat acgggtaaat
     9181 ttattggaga tagttataga gatttaacta gaattgcaaa tatgaatgaa gacttatgga
     9241 gtgaactttt tttaggaaat agagataatt tactaaaagt tatagaaaac tttgaatcag
     9301 aagtaaattt agtaaaagaa gctatattta acaatgataa aaataaatta atagagtatt
     9361 ttaaaaaatc atcaataaga agagaagctt tagaaaaata aatattaata tttaagctat
     9421 atatagatgg gtataaatat aagcgatagt gtatttaatt gtattaataa atatggattc
     9481 aatataatta aatatgctat tgatatattt gtacccttaa ctattgttat cttttaaatg
     9541 ataatgatat ttatttaaat actctttatt aacaatttat aaaacttaat tgtaaaaaat
     9601 acttattaat agtaaaataa agtgaatcaa ttatattata attgctaaag agagtgaggt
     9661 gtagctattt gaaaaaaaat agattaatag caaagaatat atcaatagca tttatagtac
     9721 tattcttttt tagtgtattt acattttttt atgtaggtaa tattaataga gtgttagaat
     9781 atgaaacaaa tgacataata acagttacaa ttgctggatg gattatactt tcatttttat
     9841 ttttaggtat tataatttac atattatatt caaaagcaaa tagtcaaaaa actatagaaa
     9901 aagtagcata tacggatttt gtaacaggtt attccaactg gagaaagttt gaattagatg
     9961 ttacaaattt attaaagaaa acatcacaaa ataataaata tgcaatggtc atattcgata
    10021 ttgataaatt taaagcaatt aatgatatat atggccataa aaagggaaat ttaatattaa
    10081 aagatattgc agatacttta aatgaattga ctgatatcaa tgaaactttt gctcgtgtaa
    10141 gtgctgataa tttcaatata ttattaacat ataacaaaaa agaggatata ataaatatta
    10201 tcaaaaagat tatggcaaat aatgaacttg taaacttatc ttttggaatt tatgaaatca
    10261 aagataagga tttatctgta agtgtatata gtgatagagc ttcacttgca aaatcatcaa
    10321 taaaaaataa tagtgatgta aattttgcat tttttaatga caaattaaga gagaaattat
    10381 tatttgaaga taagatagaa aaagaaatgg aatatgctct tgaaagtggg caattcgtaa
    10441 tgtatttaca accaaaatac aatattaaat tagataaatt ttgtggaagt gaagccctag
    10501 tcagatggca atatacagaa aaagaggtca tatatccagg tgattttatt cctatatttg
    10561 aaaaaaatgg atttattaga aagattgata tgtacatatt agaacaagct tgtaaagaaa
    10621 tccggtcttt atttgataaa ggaatttcac ctttacctat atctgtaaac ttctcaagag
    10681 ttgatttttt taaaaaagat tttattgaaa acatagtaaa tatatgtgat agatataaaa
    10741 taccatatag tttaatagaa attgaaatta ctgaatctag tatgtttgga gatactgata
    10801 ctctatttaa tgttagtaga aacctacagg atattggctt tatagttgca atggatgatt
    10861 ttggctctgg atattcttct gtaaatatgc ttaaaaatat accattaaat gtaataaaat
    10921 tagatagagg attttttgtt gatgataaag atgttgataa gagtcaaatt gttataaaaa
    10981 gcatagtttc tctcattaag caattaggaa taagggttgt tgctgaagga attgaaacaa
    11041 gaagtcaaat agaaatgtta aaaaaagcaa attgtgatat tgttcaagga tattattttt
    11101 caaaaccatt accaattaaa gaatttgaaa aattagtcta taaaatatag tcagcgagtc
    11161 ttaaatggga ggtggtgatt aagtgataag agcaaaatcg ttaaaaaatg tactgagtat
    11221 tgttttaata tttttattta caataatttc tttttctgat tttgcattta aaactaatgt
    11281 ccaggaagaa gaaaatagta aaattaattt aagagaaata tccctacaaa gttccaatgc
    11341 tataaaaata aaattagata gttctctatc ctttattaaa agtgtggcaa atatggtttc
    11401 ttattttaat actatagata actcaaaaat agttccatta ttagctaata tatcaaaaga
    11461 atctgacttt caaagaatct ctattgtatc tcctgatgga ataagtcata ccagtgatgg
    11521 caaaattatc aatgtgtcaa agtatcagta ttttaagaaa gctattaaag gagaaagtaa
    11581 tatatctgaa gttgtgaaat ctccaattga tggaaaagat acttttgtta tagctactcc
    11641 tgtatttaat aagaataaca aaataattgg tgttttatac ggttcttact acaatgataa
    11701 attagctgaa tttatagata taacaagttt taatagtgaa gggtacatag atatatttga
    11761 atctagtggt caatttgttt taaaatcttc acatacaaac aaactgatta agtcaagtag
    11821 taacatatat gatatattta aaaaagcttc ttttgatgat ggttatagct ataaaaaaat
    11881 atatgaagat acaaaaaata acaagagtgg ctttacctca tatgaataca aaggagaaaa
    11941 tcgttatgct acttatacac ccattggtgt aaatgactgg tatgtaattt ctgtgatacc
    12001 acaatatact gtaagaagaa acattgataa aataaatcaa ttagcatttt ctcttatttt
    12061 caaggtattc ttattgttta ttatgcttat aatatatatt atttataaaa acaataaatc
    12121 tcagaaagat atactaaaag ctaacaaaga aatctcatct attacaaata gcattcctgg
    12181 aggagtacaa aagtgtaccc tgggtgaaac atgcaatatt aattttttaa gtgatggatt
    12241 tatagagttg tttggttata caagagaaga aataaaaaca ttgtttaata atgattttta
    12301 tagtttaata cataaagatg atgttgaaag aataaaaaaa gaaattttta aacaacttta
    12361 caaaaataaa actgttgaat tagaatatag gattataaca aaaaatggta atacagtatg
    12421 ggttttagat aaaggggagc ttataacaga acctgatgga aaagaatatt tttgttgtgt
    12481 aactgtagat attactagaa caaaacaatt agaacaagag atggaacaaa aaaatctaga
    12541 acttgaaatg atatcagaaa atgttttagg tggtataatt ataacagaat ttaatgatga
    12601 ttttactata aaatacgcta actctggtta tctttcaatg attggatata cacgtgaaca
    12661 attagaaaat gaacttaaat acaaagcttg taatcttgtt ttttatgagg ataaaaagaa
    12721 ggctcttgaa agtatacaac atcaattaaa cacaaaagga atagctgtat atcaacatag
    12781 aataagaaga agaaatggta atattatttg ggtttctata aaaggaaggc ttattgttga
    12841 tgatggtatt gaaaaaggta tttggattct aaatgatata acagatttaa aaaatgcaga
    12901 acaaaaactt aaaataaatg aagaaagatt tagaattgca ttaaagcaaa catcaaacac
    12961 tatatttgag tatgatataa aaacaaagtc acttttaaat actagtaaag agcttgataa
    13021 atataatatt tataaaatta ctaaaaacgt tccatattct ctagtagaat caggagttat
    13081 tcataaagat tttagtgatg attttataaa catgtatgaa aatgtaataa atggagcaaa
    13141 aaaagcaagt tgtgtagtta agatgaaact tccagatgaa aattatatat ggaataaagt
    13201 taccttgact actatttttg atgaagatgg taatcctgta agagcaattg gtatacagga
    13261 agatataagc aaacaaaagg aagcagagat aagatacaat caagaaggta agtatcattc
    13321 agctatattg tcggaagcaa tgataactta tgaaataaat gtatcaaagg atacttttat
    13381 caaaggaaat gaaagttggc aaaaaccatt tggaattaag cctgacaata actattctca
    13441 aatggtaaaa actatagcaa atagtattgt acataaagac aataaagaaa catttttaaa
    13501 tacattttta tgtgaaaact tattggatgc atataaaaat aatgtgactg aaataaaatt
    13561 agaatatcga agaatgaatc aagaaaataa aatgatttgg gtcatttgta caatgcactt
    13621 aataaaagat tctattacga acgatataaa agcacttgct tatgttaaag atattgacaa
    13681 gcaaaaaaat gaagaaatta gattaaaatt aaaagctgaa agagatactc ttacaggatt
    13741 atataataaa ggtactacag aaaaattgat taatgatttc ttgaactctg aggaagcaag
    13801 cttaggaatg catgcatttt taattgttga tatagataat tttaaatctg tgaatgataa
    13861 tttaggacat gtatttggag ataaagtatt atttgaagtt tctaaaaacc taaaacctat
    13921 atttagaaaa gatgatatag taggtagaat tggtggagat gaatttatag tattcttaaa
    13981 aaatattcag tcttttgaga atatcaaaaa gaaagcagaa aaaatatgcg atatatttag
    14041 aaattcttat acagaaaata aaaagacata taaaatatct ggaacagttg gaatttcatt
    14101 tgtaccagaa catggaactg tatttgaaga actttataaa aaagcagaca tagcacttta
    14161 ttatgcaaag agcaaaggaa aagataagta tgcactttat aatgattgta tctaccaaaa
    14221 tgaacttgaa aataatataa gtgataataa tataaaatta gcagataaat gtgagaaatc
    14281 caaaccagta cttaaagaaa ttcttgattc tattgataat tatatctata tagtgaatcc
    14341 aaatacttat gaacttcttt ttgtcaataa taaggtgtct cgtttggatt tagagataaa
    14401 attaggagaa acctgttata aatcactatt aaaatctgat agaccatgta ataattgccc
    14461 tcttaacgga ttagaagaaa ataagcattc aaaattcaaa atagagacaa atacatttgg
    14521 taaaaatatc agtatagcaa gttggattaa ttgcatagat ggagaataca actgtcttat
    14581 agagtgtata gattcttctt tatacaaaaa taaataaaaa aggactatga agatatgtta
    14641 aatagtataa ctttgatact tggtataata tttacaattt actattttta tctcaaaata
    14701 gtttttggag gaatttcatt tagtgagatt ttcttagttg taggaattgt actaattatc
    14761 tatcaaatat ttaagaaaaa aattaaagaa aagaaggttt tttatagggt gttaaaaata
    14821 ataatcagca tttttttaat agtatttgta gttactgaga gtctaattat tttttatccc
    14881 aaaaatagtt tagaatcaaa aagtgattat ctcttaattt taggagcttc tgtaaaaaag
    14941 actacaccaa gtacaaccct gaagggtagg ttagacactg cattgaaata cctaaaaatt
    15001 aatgataatt gttatgtggt agtatctggt ggtaaaggaa gtggagaaaa aataactgag
    15061 gcaaaagcta tgaaagatta tcttataaaa aatggtatag ataaaaatag gataatagaa
    15121 gaggataaat ccacgaatac ttatgagaat tttaaatatt caaaattgaa gatagaagaa
    15181 catagtcaag gaaaactaag cgatttaaaa gtaaaaatag taacaacaga ttttcatgtt
    15241 ctcagaagta aaatattagc atatagaaat ggatataaaa atacgtcttt ttatgctagt
    15301 aaatcaaaac tttcatttgt accaacttac tatacaagag aattttttgc attatggaaa
    15361 acaatcattt ttgatagata ataaataaaa agactagata taaactcata tctagtcttt
    15421 tctattccct taattctaat ccattttcca actttacttg ttgtagaaat ttcaacattg
    15481 ggatttacaa gtaattgctt ataagaagtt ttatatttta cgattccaaa atataatttt
    15541 ccttcataat ccattataaa tccgaatggt cttactcttg gtttattatc ttcaactgta
    15601 gcaaaataga atgttgagtt ttctttaaaa aaattcatta ttttttcatg attaaatcct
    15661 ctttgtatct tatactaata taatgaatat aaataaaata ttcataatac taatataaat
    15721 cgatataaaa acaattacaa tattatattg attattcaaa attatatata aaattcagaa
    15781 aaaaatttta gtttacataa taaaaataaa gtcaactaaa attattgatt ttagattaaa
    15841 gtaccggatt aagcatttaa gtagatttta agcttgattt gattagaaag gtacaaacta
    15901 tcaccgaaaa aaattaaacc catttaaaaa gcaatataaa agcttgttat ttttgagaaa
    15961 aatagaccct ctaaactcaa ttagattaaa aataaaatac agaaaattat atctctaaat
    16021 atcttaaata attaagttta aattttacga tattttgttt gatgatttat aatataaaag
    16081 catactctta atcttcaaaa tttaaaaaga gtaaaaaata acaaaaaaat cactgacatt
    16141 tcactgacaa attgtaattt tgttattata aatacattga aaatacttga ttattgaaaa
    16201 atggcataaa ataatacatt ttatgccatt tgctattatt tgatagtttt taacttatga
    16261 cataagatat tttttaacat atacaataaa atataaaaaa attgatattg caaataaaaa
    16321 aaaatacata ttagatgtta tagaaaaaaa gcgcacttat aggcttaaaa tgtcacataa
    16381 aagagtttta aagaataata tattatgaac acaaattttg taatcacaaa ggagtgataa
    16441 tatggcaaca gtatcaggac aaatagtttt tgatagaaat agaagtgcta ccattgattc
    16501 tggagactca ggaatagcca atataccagt tgtattacaa gatatagcaa ctggagttag
    16561 acttgtggtt ctcacagatg catcaggaaa ttatgttttt actaatgttc caaatggtaa
    16621 ctatagaatt gtagaagctt ttggaactac aggaggagta ccaacaccag gaaattttgc
    16681 aacagcgata gtaggtccag ttccaattgc agaaatgcca cctattagtt ctgtgacaag
    16741 tcctcctatt ggttcaacaa acttagatgg tacaacacct aacacactat taataacagt
    16801 agcaggttca gatataacaa atcaaaatat attaaatggg cctgtgattt atacacctat
    16861 agagaatata ttggattctt gcgtatctgt atctaatata aacccagata acggaacatt
    16921 cggttttttt ccaccaggta caccaagtaa tacaggacct gaaatagaac cttacccaaa
    16981 tgtgacgcca gattttacgt atgttgtacc agacccaact aagtttacac ctttagatgg
    17041 agaatataca gtacaaaata ttatgacaaa tgcaatgagt aatgttatag gagcttggtg
    17101 gcgtattgct gaccatacta caggaaatga aacaggaaga atgatggtgg taaatggttt
    17161 taatcctgga gctgtatttt ttaaatcaac agtacaagtt acacctaaca ctaattattt
    17221 atttagcact tggattttaa acctttttaa ggtaacagga tatccaccac cacagctagg
    17281 tgtaagaata tttgaccaaa ataataatat actatatcaa gcaacattag gagctcaaat
    17341 tccagttaat acaaacgcac cagaatggaa agaagtaggt actgtgatta attctcaaaa
    17401 taataatcaa cttacagtag aattttttag tgaaggagaa agcgccattg gaaatgacta
    17461 tgctatagat gatgtttctt taagagaaat agctgttcca acttttactc caataaaaac
    17521 aagtaacaca gaaactgcta atgtaggtga tataatcaca tatacagtta cattagataa
    17581 tacttgtgat agccctttaa ctaatgtatt ttttagggat ttaattccaa atggtttaga
    17641 gtttatacct ggaactgtaa cggttgatgg agtatctgta ccaggagtag accccaatac
    17701 aggtttccca cttccagata ttggaggagg aacaggggtt gaagtaactt ttgatgttgt
    17761 ggttgaaagt attcctaacc caaatcctac taataatata gctactatag attactccta
    17821 tacacctgta gaaggcggta taccaaatga tttttcagta gattctaatc cagttcctgt
    17881 tgaagtaatc tcagcagata ttgaagttac aaaattatct gaacctacta tagtgaatcc
    17941 aggagaggaa ttaatataca ctataaaagt agtaaataat ggaccattcc catctgaaaa
    18001 tgtggtttta acagatgatg taccagcttc tattgtaaat ccagagtatt cattagatgg
    18061 aggagtaact tttcaaccat ggactggaag tttaaatata gggacattag aagtaggaga
    18121 gacaagagtt attataatta ggggtattgt aaatccatca acagtaggaa ttataacaaa
    18181 tacagctgta gtatcttcaa ctacagcaga cccaaacctt aataataata catctacaat
    18241 agagacagaa gtgaatttat tagcagatat tttagtaatg aaaacagcag aacctaattc
    18301 agctgttcca ggtactttat tgagatatac tattcaagta gaaaacttag gaccagcaaa
    18361 tgctgaaaat gtaatattaa atgatgatat tccagcttct attataaatc cagaatattc
    18421 attggatgga ggagcaagtt ttcaaccatg gaatggaagt cttaatatag gaactttaaa
    18481 ctctggaatt tcattaacag ttttaattca aggaacagtt agtttaaatt cttcagaata
    18541 tatagtaaat acagcaacag tttcttcaac tacacctgac ccagatttaa gcaacaatat
    18601 atctaccatt attacaccag ttaacccaca agcaggtatt tctattataa aagtagctga
    18661 cgaggatgta gctgttccag gagaagaatt tgtatataca attgaaattt ttaatgaagg
    18721 accatctaat gctacgaatg tagttttaac agatgatata ccagatgtta ttttaaatcc
    18781 agaatattca ttggatggag gagcaacttt ccaaccatgg actggaagtc ttaatatagg
    18841 tacagttgca ccagggcaat taataagaat tatcataaag ggattagtaa gttcaactgc
    18901 tacaggagat attactaata cagcagaagt aagtgcagat gtaccagaac cagttacgga
    18961 ttcatcaaca gtgacaactc ctatagttcc atcagcagat atagaagtaa taaaaactag
    19021 caatatggat acagcagttc caggagaaac tttcagttat actataacag ttacaaattt
    19081 aggaccatct gctgcacaaa gtatcgtttt gacagatgat ataccagatg ttattttaaa
    19141 tccagagtat tcattggatg gaggagtaac tttccaacca tggaatggaa atcttagtat
    19201 aggcactttg gatgctggag aaataagaag tattataata agaggaacag tgagccagac
    19261 agcagtaggt acaattataa atacagcaac aataagttca actacacctg acccaaatcc
    19321 agataataat acttcaacag atgaaacaga tataagtcca ttagcagata tttctgtgat
    19381 aaaaggcaac gaaccagttg ctataccagg gggaagattt atttatggaa ttgaaattgc
    19441 aaatgcagga ccatcttttg cagagaacgt aactttaaca gataatatac cagcttctat
    19501 tttaaatcca gagtactcaa tagataatgg agtgactttc caaccatgga atggaagcct
    19561 taatataggt actttagatg ctggagagat aagaaatatc ataataaggg gaacagtaag
    19621 tcaaacagca ataggcacaa ttataaatac agcaacagta agttcaacta cacctgaccc
    19681 aaatctaaat aacaatattt caacatcaga agcagaggta agttcatcag cagatatttc
    19741 tgtagtaaaa cgaagcaatc agactgttgt tgtaccagga gatgtactag actatacaat
    19801 tgaggtgaga aatgcaggac cgtctactgc tcagaacgta actttaacag ataatatacc
    19861 agcttctatt ttaagtccag aatattcaat agataatgga gtgacttttc aaccatggaa
    19921 tggaagtctt agtataggca ctttagatgc tggagagata agaaatatta taataagggg
    19981 aatagtaagt caaacagcaa taggtacaat tataaataca gcaacagtaa gttcaactac
    20041 acctgaccca aatccagata ataatacttc aacatcagaa atagatataa gttcatcagc
    20101 agatatttct gtaataaaat tagcaaataa aacagaagca tgtgtaggag agcaaataga
    20161 ttttgtaata gtagtatcaa atgcaggacc agaaaatgct caaaatgtta ctttaataga
    20221 caatgtttca gataagctta agaaagcagt attttcactt gatagaggtg taagtttcca
    20281 accatggact ggaagtctta atataggtac actaccagct ggaactttaa gagtgattat
    20341 attaagagga attataaaat caacatgtct tgatagatta acaaatattg cagaaattac
    20401 ttcaacaaca ccagattcaa accttaacaa taatatatca agagtgcaag tagaaataaa
    20461 acaatgttgt tgtaatgatt gctgttgtaa caactgtagt aattgttgtt gcaatgattg
    20521 tggttgtaaa gattgttgct gtaattgttg taaaaatgac ttttggtgtt gattttataa
    20581 aataattttg tataccttaa attaaactga aataaaaaat aaattcacat atgagtaaaa
    20641 tattttataa atattaataa attttctatc tttgatatgg accacattcg taatactagt
    20701 tattaaatga agtggtcctt tttaattcat taaaattatt
//
LOCUS       DAMJWC010000064        20538 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMJWC010000064 DAMJWC010000000
VERSION     DAMJWC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20538
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.064"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            40..1470
                     /locus_tag="PC503_002849"
     CDS             40..1470
                     /locus_tag="PC503_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2528815.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            1670..2254
                     /locus_tag="PC503_002850"
     CDS             1670..2254
                     /locus_tag="PC503_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF2528816.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(2358..3137)
                     /locus_tag="PC503_002851"
     CDS             complement(2358..3137)
                     /locus_tag="PC503_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2528817.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(3195..4451)
                     /locus_tag="PC503_002852"
     CDS             complement(3195..4451)
                     /locus_tag="PC503_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF2528818.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGIAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            4709..5608
                     /locus_tag="PC503_002853"
     CDS             4709..5608
                     /locus_tag="PC503_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF2528819.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            5632..7080
                     /gene="ddlR"
                     /locus_tag="PC503_002854"
     CDS             5632..7080
                     /gene="ddlR"
                     /locus_tag="PC503_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF2528820.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            7139..7945
                     /locus_tag="PC503_002855"
     CDS             7139..7945
                     /locus_tag="PC503_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2528821.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            7971..9890
                     /locus_tag="PC503_002856"
     CDS             7971..9890
                     /locus_tag="PC503_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2528822.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGFIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(10132..10479)
                     /locus_tag="PC503_002857"
     CDS             complement(10132..10479)
                     /locus_tag="PC503_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF2528823.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(10466..12394)
                     /locus_tag="PC503_002858"
     CDS             complement(10466..12394)
                     /locus_tag="PC503_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF2528824.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(12806..14995)
                     /locus_tag="PC503_002859"
     CDS             complement(12806..14995)
                     /locus_tag="PC503_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF2528825.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKFGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDIYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            15326..16057
                     /locus_tag="PC503_002860"
     CDS             15326..16057
                     /locus_tag="PC503_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2528826.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LTLNIELKTDKINYPNIEKGVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            16137..16772
                     /locus_tag="PC503_002861"
     CDS             16137..16772
                     /locus_tag="PC503_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2528827.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(17023..17616)
                     /locus_tag="PC503_002862"
     CDS             complement(17023..17616)
                     /locus_tag="PC503_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF2528828.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(17687..18550)
                     /locus_tag="PC503_002863"
     CDS             complement(17687..18550)
                     /locus_tag="PC503_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF2528829.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            18713..19882
                     /locus_tag="PC503_002864"
     CDS             18713..19882
                     /locus_tag="PC503_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528830.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNSNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            19983..20459
                     /locus_tag="PC503_002865"
     CDS             19983..20459
                     /locus_tag="PC503_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2528831.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSIPKWCSHWPKSVEKSGEFNWEDEIEF"
BASE COUNT         7551 a         3064 c         2638 g         7285 t
ORIGIN      
        1 tttaatatat cattaaaaat ttaggaggaa aatataaaaa tgaatttaga tttggaattt
       61 tatcaaaaaa tattagaagc ttcccatgat gaaatatgtg tttctgatga taaaggaata
      121 ataatatatt gtaataaagc atttgaagaa aattatggtc taaaaaaaga agatattttg
      181 ggaaaaaatg tttctttttt agaagactct ggatattcaa caaaaagccc cataccaatt
      241 gtattaaaaa caaagactaa attttcactg gaacaagata ctcaaacagg gaaaaagctt
      301 atcataactg ctacccctat atttgatgaa aatggacact tagaatttac tgttgaaaat
      361 tgtagagata taactgaact taataatata aaaaataaac ttgaagacac aaaaaagcaa
      421 gtaaaaaaat ataaatctga agtagaaaca ctatacagaa ctgcacttag aattgaagat
      481 actgtaatta tggacggaat agttatgaga ccaatcataa acacagtaaa tcatgtttct
      541 aaaacggatg taagtgtact tttattgggt gaatctggaa caggaaaaag ctcacttgct
      601 agatatatac accacaacag caatagatct aatggcccat ttataacaat aaattgtgca
      661 actatatctc cacaacttct tgaatctgaa ctttttggat atacttcagg tgcttttaca
      721 ggtgcaagta ctaaaggtaa agttgggctc gtagaattag ctaatggagg aactcttttt
      781 ttagatgaaa taggagatat accacaaaat ctacaggcaa aatttttgca attaatacag
      841 gatagaactt ttactccagt tgggagctta aaaaataaaa aggtcgatat aagaattata
      901 tctgctacaa atgttgattt agtttcaaaa gtaaaagaaa aaaagtttag agaagattta
      961 tactatagat taaatgttat agaaataaaa ttgcctcctc ttagagaaag aagggataat
     1021 ctagtggaaa ttataaaata ttattttaat aggtactcaa gtgacttcaa cctaaataaa
     1081 actatttcta aggaagctat ggatgctatt gcaaattata gattcccagg caatataaga
     1141 gaattacaaa atataattca aaaaatcttg cttacttgta cagataatca tataacaata
     1201 gatgacttac caaacattct tacaaaaaat atacatatta ccaataatgg aaataaaaca
     1261 catatatccc aaattaataa ggttattata tctgactcaa aatctactaa ttataaaaat
     1321 aaaaattttg acactttaat taaagagtat gaaaaaaata taattttgga tgcttatgaa
     1381 aaatttggta gttcttataa agtagccaaa caccttgaaa tctcacagtc taaagccaat
     1441 aggttaatta gaaagtatac taatacttaa ttttaaattt gataaataaa aacttaacac
     1501 tatttacata ttgtaaattt ggccatttac tgttattatg aatatggttg aaattattta
     1561 aataaatact gttgacttag tttcatatat ttaccattaa acttttatca taaatatcat
     1621 atcataataa tatatttaat aagtctaata aactatacga ggtgtaaata tgttaatgaa
     1681 tacccatttt attatggcaa aatcaatact tgataatata gatgaaaata aaacattctt
     1741 tataagcgaa aaaaatttta tatatggcaa tataaagcct gatgcttttt ctaaatataa
     1801 attaaaaaaa cattatttag atgagtcatt taatatgatt gtttctaaaa taaactatct
     1861 atgcagtctt aatatagata gtctttctaa atacttttca gtaagtagac ttagtcagga
     1921 actaggagtc atatgtcatt ttttatgtga ttttttctgt gtagctcaca gtgaacgttg
     1981 ggaatttaag catagcttaa ataaacatgt tacttatgaa agagaacttg gagcatttgc
     2041 aaaagatgtt gatttatcta aaattaaatg tggtactata aatagtagtt ttgagaagtt
     2101 ttttactaaa ctttatagtg attacaaaaa gaaaactgat tatatgaatg atttaaaatt
     2161 ttcagcttat acttgtaata gtgtcataaa ttatatactt gactctattt tatctaatac
     2221 aataaaatca tatcatatag caaattgcgg ttaacttaag aatttttaaa cttatataaa
     2281 cttataattg aatataatta aaatgactgc tctatagaat ataattttat acttctctag
     2341 gacagtcatt ttttatacta actatttatc tccattataa catctatggc actttttaca
     2401 ctatctacta cataatttgc actttgcttt acatcttccc ttgccttaga cattgcaaaa
     2461 ctatatttaa atccttctaa catgcaaata tcatttggag aatccccaat agtagcaact
     2521 tcatctggac ttacatttaa cgtttttatt acatgctcta tacttcctct ttttgacaca
     2581 cttttaggaa ctatatttaa agtatatgtt ccagaaaaat atatttctaa gacttcacta
     2641 aactcacttt ttagataaag ttctattctg gataactctt ccaaattttc agaacatacg
     2701 cctatatttc ctataagatt atcaaaacta cttctttttt caaaatctgg gtcaactata
     2761 aagtcactag aataatgtct aaaagcagtg gtatcactac ccacaattac atcaccctta
     2821 tatttaaaat aaagttgtgc atcacttgac tcaaatctat caatgacttt ttttactaaa
     2881 ttatcatcta tcgttctttt aaaaattaca ttataatctt tatcatatat aaatgaacca
     2941 ttttcacata catagtatcc attcatatct aaactatctt tgataatatt atgtgcttgt
     3001 ttaaaaattc tacctgtagc aacattaaac tgtactccct ttttttctat ttcttcaatt
     3061 gctactatat cttcttttgt tatggttcca ttttcatata gagttccatc taaatcacaa
     3121 aatatatgtt ttatcataaa ttaaaagcct ccaaaaacaa ttttatattt tactaatact
     3181 ttaatcaaaa taacttaaag cttttctaat tgtattctca attcattaag caaatctcta
     3241 gtagctctta atcttatctt tcttctatcc ccattaaata tatttttctt tactattgtt
     3301 tttccattta tatatattgc agtataaacc agtcccacag gcttctcttt ggttcctcca
     3361 ccaggtccag ctactccagt tgtagatata cctatattag ctttaagtcc tttagcaatg
     3421 ccctcagcca tttctatagc tgtttgctca cttactgctc caaactcttc caaagtttct
     3481 ctttttactc ctaatctttt cattttagaa tcattagaat atgttacaca accttcaaga
     3541 aatacagagg atatacctgg atagtttata agagatgaag aaaccaaacc tccagtacaa
     3601 gattcagcca ctgctattgt tagatttttt tctacaagta gcttagaaac agcatcttct
     3661 aaagcagtct ccccttcaga tatggaaata tctccttcag tatatacata tttaccaact
     3721 ctacttttta ttttttcttc tactggtttt attaatttaa aagcttctct ttcattttca
     3781 gcctttgcag ttattcttat tgtaacttct aattcttttg catataaagc aactgttgga
     3841 ttagtctgct cattaattat atcgagaatt tctaattcta gatttgactc acctattcca
     3901 tataatctta aagtcttaga tactagcatt tcatttgtga attgttgtaa gtaaggtttg
     3961 acactctcat taaacatagc tttcatttct cttggaggtc caggcaatac tattataaat
     4021 ttaccatctt tttttaaaat tgcccctgga gctgtaccat tattattttt tagtactata
     4081 gcatcttttg gaaagtacac ttgtttcata ttattttcgg ccattttttt ccctgtttta
     4141 acaaagaaag attccaaaac ctctagtgaa ggtttatgta gttctaattt ctgaccaaag
     4201 tattctgcag cagtttcttt tgtcatatca tcaccagttg gcccaagacc acctgtagta
     4261 attacaaaat cacttctctt taagctttca tcaaaacatt ctaaaagtct ttgtttgtta
     4321 tctccaacag tactctgatg gtatacttct attcccaatg atgcaagttc tttagctaaa
     4381 aattgagaat ttgtatttac tatatctccc aataatattt ctgttcctac acttattatt
     4441 tcagctttca aaatttatca ctccttgatt tatagccatt aagactagtc ttaagttcat
     4501 aacaataatt ttagcaaaaa taataacata aataaagtta aaaaatcatt taaacatatc
     4561 tttaaactag attattattc taaaaccaca cataatataa acttcgtata tagtggtact
     4621 ttcatcctca actgttaatt catataatta agtatgtaaa taaaaagttt actttaaaat
     4681 aataaaaatt aaaataggag tgtataatat gaaaatagca gttataatgg gtggaatatc
     4741 atcagagaga gaagtttctt taaattcagg aaaagagata tataataacc ttgataaaaa
     4801 taaatatgaa gttgtaaagg taataataga tgataaaaaa gatatattta caaagatacc
     4861 agaagatata gattttgcaa tacttgcttt acatggaaaa tttggtgaag atggatgtat
     4921 acaatcaata cttgagacta tggatatacc atactctgga tgtggacctc tttgcagtgg
     4981 gatgtgtatg gataaaaata taactaaaaa aatgcttaga gattcaaacc tacctactgc
     5041 tccatgggtt ttagtaaaat cagttgatga aatagactat gatgaaatag ataatatagg
     5101 ttatccagta tttataaaac caaactcagg aggttcaagt gtagccacat tctttattca
     5161 ttctaaggat gaagttgaag aagcagttag aaaaggtctg gaagttgatg aatttgtaat
     5221 gattgaaaaa tatataccag gtggagaata tacttcattc atattaaatg gagaagtgtt
     5281 ccctacaata tctataaaat ctgattcagg attctttgat tatgaagcta aatactcagt
     5341 tgaaaaaggt gcaaaggaag aagttgttta cttagatgaa gaacttcaaa aaagagtaaa
     5401 cgaaatttct gagacttgtt ggaaaatttt taattgcaaa gcatatgtaa gagttgatat
     5461 gattataagt gaaggtattc catatgttct tgaactaaat actcttcctg gaatgactca
     5521 aactagttta attcctagaa gtgctgctgc tagaggtatt aagtacagtg aactattaga
     5581 taaacttata gaatactctt taaattagat gaaataattt gaggtggtaa tttgatattt
     5641 tcaaatctaa aattaaatga taatgaacca atttatatac aactaaaaaa ttatataagt
     5701 gatatgatat caaaaggact aattccagac aatagtaagc tcccttctac aagggagctt
     5761 agtcagcttt tacaagttag ccgaaattct gtagttttaa cttatgaaga attaaaatca
     5821 gaaggattaa tctactctat ttcaggaaaa ggtacatttg ttaaatcaaa gaataagtct
     5881 tcaaatacta catggtcatt aaactgggat tgtttagaga atacatactc taaaaaagcc
     5941 aatgaattgg acattataaa aagtgaaatt ccttggagct ctgacctgat ttcctttaaa
     6001 agtatttctc cagatggaga tttattcgac atggaagaat taaaaaaatc ctttttaaat
     6061 agaatttcac tagaaggaca taaattactc aactatggat atgcacaagg ttataagcca
     6121 cttattgact atttactaga atatatgaca aacaaaggtg ctgatataag taataaagat
     6181 atactaataa caaatggatt cacagaaggc tttgatatta ttatgtcatc ttttacccaa
     6241 gaaaaagact acataatatg tgaaaatcct actcataata ctgctataaa aattatgaaa
     6301 tctcataacc tcaatatctt aggtgtagat ataaatgaag atggtttgga cttcaatatg
     6361 ctagaagaca atttagttaa gtataaaaat aaaataaagt ttgcatacat tacaccctct
     6421 tatcacaatc ctacaggaat tgtaatgact cctgaaaata ggtacaaatt ctataatctt
     6481 atgaaaaaat acaatatagc aattatagaa gatggattta atgaagaatt actctacaat
     6541 agttctcata tatttcctat ctgttcccta gataatatga ataatggggt cgtatatatt
     6601 ggtagttttt caaaaatttt atttcctgga atgagaattg gatggatatt tgcagataaa
     6661 aaagtaatca ataagctaga aagtgtaaaa aggtgcagaa acatacatgt atccttttta
     6721 gaccaaggaa ttttatttga ttatttaagt aatggaggtt ttgaaaaata cattaaaaaa
     6781 atacgtaaat tctatggaga caaatttaac tttgcatata aatgtataaa aaaatatata
     6841 aaaacagaat atatcttggg tgatggtggt ttgcatatat ttataaaact aaaaaatata
     6901 gatactagag ttttattaga aaaatgttat gaaaaaaatg ttatatttat gcctggagac
     6961 ttatttttta cagataactc tggttttgat actttaaggc tcggattttc taggttgtct
     7021 tttgaagaca ttgaaattgg aataaaaata attggagaaa ctataaatga aatgttctag
     7081 gttaactaaa tattgttagc ctagtttatt tttatgaggt ataatatata tagtttatat
     7141 gaatctaata ctgggggata atatgagtaa aaagtcaaaa cgaagaaaaa ttaataaatt
     7201 aaaattaacg attgtaataa ctgtattatt tcttgcttta ttatctatat atgagatact
     7261 gttctctaat cccaacaaaa aaggtaatat aaagagtcaa gaaactatgc aaaataaaaa
     7321 taatacaaca gatgattcta aaaataatca aagctctacc aaaaagcagg aagataataa
     7381 tatcaaacct actttttcat attcttcaat accagataat ataaaaaata aaatgattgg
     7441 taaatctatg cctactgatg aacctataag ctttgatagt ctatcttatt taaaacttac
     7501 atattatgga tttgatgaaa aaactcatca aggagaaatg atagtaaaca gtgaactagc
     7561 tccagaagta gtggatattt ttaaggaatt atacgaaaaa aaatatccaa ttgaaaaaat
     7621 taagttaata gatgactatg atgctgtaga tgaaaaatct atgtctgata ataatacctc
     7681 atcattttgt tatagaacta tagctggtac aaatgtagtt tcaaatcatg gtaaaggacg
     7741 tgctatagat ataaacccat tacagaatcc tcaagtttct ggaaatgatg ttacacctaa
     7801 agtaagtaca gtttatgctg ataggtctag cacaaaattt ggaatgataa aaaaaggtga
     7861 tgattgttat aatgcttttg taagcagagg ttggagttgg ggtggctatt ggaaaaaccc
     7921 agattatcaa cattttgaaa aataatagat tagaaataaa ggtgaattat atgaatttaa
     7981 tgacattgga aaatataagt aaaagctatt ctgaaaaaaa attactagaa aatatatctc
     8041 ttggaataaa tgaaggggaa aaaataggat ttattggtgt aaatggtact ggtaaatcta
     8101 ccttactcaa aattattgca ggagttgaag aaagtgagac tggtaatata acaaaaacta
     8161 atggtattag gatagaatat ctacctcaaa atccaactta caatgaaaat tcaactgtac
     8221 ttgaacaagt atttaatgga acttctgaag aattaaagct acttggtgaa tatcaagaaa
     8281 tcctagaaaa acttaattca aactttacag aggaattaaa taaaaaatta ttatcagtac
     8341 acgaaaaaat agatgcctta aatctttggg atttagaaag tgaagctaag tcagtactta
     8401 caaagcttgg tataaatgac tttaatcaaa aaatagcaga actttctggt gggcaaagaa
     8461 agagagtctc tctggcatca gcccttatta caccttgtga gtttttgata ctagatgagc
     8521 ctacaaacca tctagacaat gatactatag attggcttga ggaatatctt aattccagaa
     8581 aaggttcatt gcttatgata actcatgata gatacttttt agaccgtgtt acaaatagaa
     8641 ttattgaact ggacaaaggt agattattca gttatgatgg gaattattca atatttttgg
     8701 aaaagaaaat ggaaagactt tcgctagaag caagtattga agataaaaga caaaatttaa
     8761 taagaacaga gcttgcgtgg gtaagacgag gagctcaggc tcgtagcact aaacaaaaag
     8821 ctcgtttaca aagatttgat gaacttataa atagagattc ttttaaacct gatgaaaatc
     8881 tcgatatatc tgttgcatca agtagacttg gaaataaaat aatagaaata cacaatatat
     8941 ctaaatcatt tgaagaaaat actgttatag ataatttaga atacacttta actcgtacag
     9001 atagaattgg tataataggc aaaaatggta tgggtaaatc tacccttata aatatactta
     9061 atggagaaat agagcctgat agtggatata tttcaattgg agaaacagtt aaaataggtt
     9121 gtttttctca agacgactct catatgaata ttgatatgag ggctatagac tatgtaaaag
     9181 aagctagtga ctatatagaa acttcagatg gtactaggat tacagcttct caaatgtgtg
     9241 aaagattcct ttttaatggt actatgcaat atactttgat aggtaaatta tctggtggtg
     9301 aaagaagaag actacatctt cttaaaatcc ttatgacagc tcctaatgtg cttcttttag
     9361 atgaacctac aaatgattta gatattgaaa cgcttaaaat attagaagaa tacctagacg
     9421 aatttaaagg tgtagtagtt acagtatcac atgatagata tttcttagat agaatttgta
     9481 ataaaatatt tgcatatgaa ggtaatggaa aaattcatat ctatacaggt aattacagtg
     9541 attatcttat ttatagagag attcaaggaa ttgaatttga agaatctaaa agggaatcag
     9601 ttaaaaaaga tgactctact accccaaaaa aagaaaaacc taaaaatgat aaaaagctta
     9661 agttctcata taatgaacaa agggagtttg aaaatattga ctctgatata gaaaaactcg
     9721 aatctaaaat tgcaacactt gatgaaagta ctgcaaaatt ttcaactgat tttactaaac
     9781 tccaagaaat tttagatgag aaatctaaac tagaaaaaga acttgaatac aaatatgaaa
     9841 gatgggaata tttaaataat ctagctgatg aaatagctaa taataagtaa tattaaaata
     9901 atcttaagtt taataagttt tgctttaaat ctgtaattta taaatatttt aaaggaagtg
     9961 tctcaaaatg aactttttag ttttatgaga cactcttttt tatgagaaat caaatatatt
    10021 ttcatcattt caacaataca aaagaggctt atctctattt tgagacagcc tctttcataa
    10081 ttaccttcta atttatatgc tctaatatat ctataataat tcttattata tctatatatc
    10141 cagtctttca atatagtgac aattaacttc aatatgattt aaaaatacta acaacctttc
    10201 ataaagtgga tgagattctt ctccatattt agcttctagg ttcttgccta tttctctaac
    10261 agtcctttga ccatcaattt gtaaaaaaac aaaactggaa tattcatcta gttctatttt
    10321 tttgtattta ggtattctag cttttaactt tctaaaaaac ttttgaattt tatggtcctg
    10381 tttttcaagt atagtaacaa cacgattttc agctacttca tattcaagtc catcagtaat
    10441 tttaaataca atatctaaaa catcattact cttgctcatt attttttact ttagataaaa
    10501 caataggtaa tgctgtaagc acaactaaaa ctactaataa agcaattgcc attgaatttg
    10561 ttgcagcaaa tccacttggt acctttggag ttacaactcc agttacttgt aatattatac
    10621 ctattaaacc aatgatagaa ccaccagcaa caagaccaga agataaactt ataccattag
    10681 aaactttaac ttctttttct ttttcagttt tagatactaa ttcaacaaat aaacgaatta
    10741 atgctccaac taatattata gaagtagttg caattggtaa atagaatcct atagctatag
    10801 tcattattgg taaatttaat gcatatagaa ctattgccat aaatactcca acaataatca
    10861 taacccaagg taaactacct gacataatac cagaagttaa tgttgacatt aagtttgctt
    10921 gtggtaatgc aaattgtaca ttatcaccag ttgctctaag ttggtcagaa agtaataaaa
    10981 ttactcctac aacaactata acaccaacta tacttgcaat tgtaaagtaa cgttgcattt
    11041 cgtttttgct accaccaata atataagtta ctttttgaga ttgagtataa cctccagcta
    11101 tagcaatagc aacaactata aatgaaccaa ataaaagtaa tgatttatta gcttctaaat
    11161 cagtccatcc cattataaca aacactaatg ttacaataac tagagaagct atagtcatac
    11221 cagaaactgg aagatttgat gttccgattg ttcctgttaa acgaccagct actatgacaa
    11281 ataataaaga taataaaaga gatatgatag ctccaataat tgccataaca atgttaccag
    11341 aaattaagaa tgctgctaaa aatccaataa ctactccacc taataaaagt atcatttgta
    11401 tagatgaacc ttcttctcct tctccagcac ttgatttagc tttaagtgtt tcttttatag
    11461 aagcgattat agttggtata agttttattg caccaataat acctccacaa agcatcatac
    11521 cagcacctat atattttaca taactactag atattgctcc aacatccatt tggttaagag
    11581 gcattgcagg attattccat accatagctc catctttagc catatctgta aagtatccta
    11641 ttaaaggtgc tataccaaag tttgataaaa tacttcctgc aaacattgtt aaagaaactt
    11701 caagccctac tataaatcca attcctaaaa gtagaggatt tacttcaata tcaaatttcc
    11761 atttgtagaa tttgcttcct acaagactca ttacattgtt tgctacattt aagaatgaac
    11821 cagttaatac agtaataaat ccacttatta caaatccaat tcccatgtac ttaattgaat
    11881 ctccaccagc ctctgaagca acaagtgtct cagatatagc cattgattct gggtacataa
    11941 gtttaccatg ttcttcaact attagatagt tgtgaactat agcagcaatt cctataccaa
    12001 ataaaactcc accaactcca acagctaagc cttctaagaa tgtaatttgg cttccaatta
    12061 atataactgc tggtaatacg aaaataaatc cacttgcaac agattctcca ccacttgaca
    12121 taccttggat taagttttta ccaagaatac cctttgaacg agcaaatgct ccaacaaaag
    12181 cagaacctat tatagctcct ggaatacctg cggcaactgt aagaccggct ttcattccag
    12241 agtaagttgt agatgcggca aaaatggcag ctaaaataat accgataatc agtacagcta
    12301 catttccacc ggttctggac ttatctgtga tatatggaac gtaatctttt ccactaacct
    12361 caccataagc acccttaggt aattttttgt tcataaaatt ttcacccctt ttcaatttgt
    12421 atatattata acatatatac atataaaact taacttttta ttattttaca aatagcgagt
    12481 caaaactact aaaatttaac cctatattat taatttctac ttttagatat ttttatgcta
    12541 attttctttt tatttttcaa ttctactaaa aactattaag atataaaata aaaaaatttt
    12601 ttaatgtaaa attaattttg taaaaaaaat gctttaaaac acggaaaagt ataaaaaata
    12661 caataatcat tcttataaat aaattttcac catagtaaat atatacagaa aattcttgtt
    12721 tttatgcaaa ttgattattt tataaaaata agtgtcataa agaaatgtct gaaatcactt
    12781 tatgacacct atcataataa aaaaattatt ctggtaatgc tcttttattt acttttccga
    12841 ttggtgtaac tggtatctta tctatcctca ttattattgt tggaatcata tatggaggta
    12901 gatgctcatt taaatattct ctaatagttc tttcatttat cttaccacta tcttcctcat
    12961 caattacata atatgcacat atataaatat ctccatcatc atttgttctc gatatacaaa
    13021 caacactttt aatttctgta atattattta ttatattttc aatctcatat agctctatcc
    13081 taaactcatc aatttttact tgattgtcca tccttccaat ataatctaaa tttccatcat
    13141 ctaaccatct tactaaatca ccagttctat acattaactt attatgttca caagttttgt
    13201 aaggattctc tacaaatact tgctctgtta gccctttttt atttaaatat cctcttgata
    13261 tttgaatgcc tgatagacat agctctcctg gtgctccaat tggacatagt ttgttctttt
    13321 tatctaatac atatgcataa gtattaaata taggttttcc tattggtatt tttccatatt
    13381 ctctgtccac atgaaaagaa gtcgatacaa cagtaaattc ggttggtcca tactcattat
    13441 atagttcata attacgcttt ctatatcctt ttaatctttc tcctccagtc tgtacaactc
    13501 taagtgaatt attattgcaa ttttgtataa ataaccttgc aaatgctgtt ggcaatgcta
    13561 gtatagttat gtcattttcc tcacagtatt catttactgt atattcatca aatttagctt
    13621 cttcaggcat aatatctatt gatgcaccta caagcaaata agggaatagt tgtttcatta
    13681 cagcatcaaa actgaaactt aagtatatac cacatatatc attttctgta gcgcttatag
    13741 attttacgct ataataacac atatttacta aactcttatg ttctatagct atggtctttg
    13801 gcctaccagt tgaccctgaa gtagatatcg tatatgcaca atttgatgat gttatttttt
    13861 cagttaattc atatccaaac ttaaacattt cttcatcatt tatatcgagt actatggtat
    13921 tctcatttac aaccttactt ttgagttcat ctgtagttat cactactttc gcattactat
    13981 cttcaagaag gtaattcaat ctttcttctg gattacttgt gtctattgga aaaaatgctc
    14041 cccctgattt cataatccct attgctgtaa taattatgtt aatatctctt ggtaacatta
    14101 cagctactat gtcttcactt tccactccta tatgatttaa ataacctgca agtttatcag
    14161 ttacttcatc caattcttta tatgttaact ttctattttc atccctagca gctatattac
    14221 taggtgttac cttaacttgc tccctaaata aatcaacata acttttatca tagggtactt
    14281 catattgatt attattaaag tcttccaata atactttttc ttcttcctta catacaaatt
    14341 ctaaatcttc tattaaaata tcattatctt ctattatttg ctctattata taatcaaatt
    14401 gatttaaaat tcttctaata gtttctcttt tatatataga tggtttatac tttattttta
    14461 ttttaagtgc cctcttagta tatactatta cagataaatc atatcctttt ttttctatgt
    14521 cataatcata tgataaatca aaacttttag ctataaatat tgtgtttata agcttagtat
    14581 ttagatgatt tttattctct atatctgata acaaatagta tccatactct aaagacctgc
    14641 tccactgcct ttttagcttc cttacaacat ctataaattt ttcactttgt ctaactctta
    14701 ctcttattgg aattatattc attgttttac caaaaactac atcatcttca tatatatact
    14761 tttgaagtat aaggccatat atagtttcta tgatagagtc tatgctaata ttgttcactt
    14821 tagaatattg aattaacctt tcatgtttct caatattcat cttaaaaacc tcatctacta
    14881 cttcatcaga acaatcttta taaaaaaaat catttggaat ttttgctata ttcgtataat
    14941 catctaacaa atccatccaa taattcatag ctcgttctaa attaacttca tacatatcaa
    15001 aattccccct tactactaag tctatagaaa aaattctttt ggaattttat tttcacaata
    15061 tataaatata ttaataatac atatgcaagc tctaaaaaca tgagcttgca taaaattaca
    15121 cttattatga ctactaaatt cgtaatattt acaatgttta aaatatatta taacacatat
    15181 atgattttat ttttctacat ttatataata tataaattac aaatagttat ttaactaata
    15241 tataacaata ccttttggaa tatgatatat tatattaatt aaatttttat aagataagtt
    15301 atacttatag gagggaacca tataaatgaa tatttatgct catagggggt ttagtggaaa
    15361 gtatccagaa aatactattc tagcttttaa aaaatgtttg gatatggata tatatggaat
    15421 agaacttgat gtccacagaa ctaaggatgg aaaaattgta gttattcatg atgaaaaggt
    15481 tgatagaact tttaatggac atggttttgt aaaagacttt actttaagaa aattaaaaac
    15541 tctaaactca tcttttgaag gatatcaaag caataaagaa tgtaaaattc caactttaga
    15601 agaagtatta attctaatct cacctacaga ccttacttta aatatcgaac taaaaactga
    15661 caaaataaac tatcccaata tagaaaaagg cgttttagag cttattttaa agtataatat
    15721 gaaaaataga gttcttatat ctagtttcaa cagcaatagc ttaaaaaact ttcataaatt
    15781 agaccctagt gtaaaaacag gattattgtg ttatttacct ataaacaatg tagtcaattt
    15841 tgctaaattt ctgggtaata gttatcttca tccacctcta gttttagtaa atgaatctct
    15901 aattgaactt tgtcacaaaa atctacttgg tgtcaatgta tatactgtaa atgaagagga
    15961 tgatatacta cactgtctaa aactcaatgt agatggtatt tttactaact atccagatat
    16021 tgcttcaaat cttttacact caaaacaata cagctaatta tacaatagtt tgtactcctt
    16081 gacttttata taattaatat gtacaatttt attaaattta tcttggaggt ataactatgg
    16141 ataacttatt aaatgaactt gaagctttaa agagtaattt agataatcta ccaatagaaa
    16201 aaatagaaaa ttatgatttg agtaaaactg ctttatttat aattgatgtt aataatggct
    16261 ttgcaagaca aggtgcatta tactctccta gagtagagtc tttaataaag ccaattgaaa
    16321 tgtttacaaa aaaaatatca aacaaattaa atagagtaat agcatttact gattctcata
    16381 ctcctaaatc aatagaactt ttgagttatc ctgttcactg tttggaaaat gatgtagaaa
    16441 gtgaattggt tgatgaactt aagtcgatag aaaacctaca aattcttcct aaaaattcta
    16501 ctaatggttt ttttgcatta gaaaatttgg attttgataa tatagataat ataattatag
    16561 ttggcgattg cacagatata tgtatatatc aatttgcaat aactctaaaa tcatatttta
    16621 atcaacataa tattgaaaaa aatatagttg tacctatgaa tttagtagat acttatgata
    16681 ttcctaacgt tcaccctgct gagattttaa acttagtatt tttcaacagt atgattcaaa
    16741 atggagttaa tgtattaaaa gagattcgtt aagcttctaa tactttacat cccatataat
    16801 acaattatca gatatttatt tttaataaaa tttctaatag aaaaacacag ttttagtgag
    16861 aagattacaa tttaaaacac tatctattat tactaatctt cacaatataa aaaatcgcag
    16921 tttagatatt ccttatacaa atttataagg aataataaat tgcgattttt atttttaagt
    16981 agtacaatta attgatacta cttcagtatt taaattcatt ttttaataat catacttatt
    17041 cgtagtttcg cacattacta cctttatttt tttattaaac atattcttat attctaataa
    17101 aaactcattt agttctgaat ccataagatt tatttttcta tcactacaaa gcattatctt
    17161 ttcttggtcg attattacat taatatcatt taagtcattt tttataaatg ttgttataca
    17221 actctttggt tggatttttt ctccatattt ctcataaaat cctgcactct tcttaaatga
    17281 ctctaaatct tctgtagata ctttgctgga agtattatta ctcataaaac ctgccgtaga
    17341 agggtcgatt ccaaagtttc taagttgttt ttctacttct tcagtgtcca taccatatct
    17401 ctccataaat tgcttttgta ttttcataaa tttttcttga gatatgttgt tatctctcat
    17461 ataatcgaat atttttcttg aaaactcagc catagacatc tttccatcca taacagaaaa
    17521 atataagtta tatatgtatt gctcaaattt atctacatca gaatctttaa ctttgttctt
    17581 tagttcgtta aagtctatta ttctatcatc agacattttt catcctccta gctaaatttt
    17641 tacttgtata agattatacc atatttctat tatatttata tacacactat ttttttaatt
    17701 taacgatttt ttctgtagca tctaattcgc acattctgcc caaaggaata gttatcattg
    17761 ggatacaatg tcctgactga agattatata tagaaggttt attgacctta tttgcaaatt
    17821 ctattagtaa ttccatcaaa tcattttctt caatacaatc cttaaaatct ccaaaaatta
    17881 taccattaca ttcctcaagt tttcctgaag aatatagttg tgttaacatt ctatccagtt
    17941 tatattgagg ttctccaatt tcctcaataa acaaaatttt atcttttgca tctatttcat
    18001 attttgttcc cattgtggca attattaagg ataaatttcc tcccattatt attccctctg
    18061 ctttaccttc acatacagta taaatctttt cttcttttgg attttctaaa tataattcat
    18121 ctttaaattc taaagcattt accaatgatt tataggtaaa tttatcccat ttacctacat
    18181 ttgctgccat tattccatga tatggtaaaa gaccacaatt tttatagaaa gctaaattta
    18241 aacctgttat atcagaaaaa cctataaatg gttttggatt ttgctttatt atatcataat
    18301 ttattttatc caatattctt gttgttccat aacctcctct taagcacata attatatcta
    18361 catctttatc taaaaacata tcttctatat cccttgctct aatatcatca ttaccagcta
    18421 aataaccttt ataatttaaa ctacaacttt cagaaaactt aacttcataa ccataacttt
    18481 ctaaattaaa ctttatttcc tccaaacttg tatttcttaa tggcccagat ggcgcaatta
    18541 ttcctaacat ttaaacacct cttcttataa aatgatatat tcttctccat actaaatatc
    18601 tctaatataa ttataagata ttttatttgt acttgataca taataatgat ttacataaaa
    18661 taatataatt aatgaagaaa aataaatttt taatatagtt aggatgtgtt ttatgcttaa
    18721 tataaaaact ctttgtcatg agataaatga ttgggttata aatataagaa gagatttaca
    18781 taagactcca gaacttggat tagaagaatt tcaaactaag aaaaaaatta ttaaatactt
    18841 aaatgaaata ggtataaatt atattgaata taagaatcat acagggataa ctgcatacat
    18901 taacgtgagt ccaaactttg aaacagttgc tataagagct gatatagatg ccttacctat
    18961 aacagaagaa cttaattatt cttataaatc tattaatatt ggcaaaatgc atgcatgtgg
    19021 tcatgatgca cacactgcta ttttactggg tacttgtaat atactattta aattaaagga
    19081 ttacttaaat gtaaatgtaa aattcttttt tcaacctgcc gaggaaacta ttggtggggc
    19141 tcaacttatg atagaagatg gatgtcttga aaacccaaat gtaaaatata tatttggact
    19201 tcatgtaaat tccaatatca acaaaaatct aattgaatta aaatacaaca ctctaaatgc
    19261 ttccactgat acacttcaat taactgtaca tggttcaaaa tgtcatggag cttatccaca
    19321 tcaaggtatt gatgctattg ttatatctgc tcatattatt acagctctac agacaatcgt
    19381 tagtcgaaac acaaatccaa ctgattctgt ggttatttct ctaggaaaga ttgaaggtgg
    19441 aatcaaggaa aatatagttt gtgataaagt ggttataagg ggtactttga gaaccttgac
    19501 tcctgaaact agagagtttt caaaaaaacg aattagagaa atttgcgatt ttacttgtaa
    19561 aacatttgga ggaagtattt ctgttgaaat tgaggaaggt tatccagctc ttatcaattc
    19621 aaaccatcta gtagattacg tcaaacaaaa tgctgtagaa ttgtttggag aagaaaatat
    19681 tatccttaaa gactcgccca ctcttggggc tgaagacttt tcgtattttc taagacactg
    19741 tgaaggagct ttttaccacc ttggttgtgc aaatcgtgaa aaaaacatta cttccccttt
    19801 gcatacctct acttttgata ttgacgaaga ttgccttatt actggtgtca tgctccatgt
    19861 aaaaaatgta ttatcattct aactattaat atttttattt attattttat attgaccctc
    19921 acatgatgtc atgttatacc ctaaaattac aaatgataaa ttaaataatt ggaggtaata
    19981 ttatgaaaga aatattaata aatcctatag gtaaaatatg tattcaaggc gaagaggtct
    20041 ttattaaatt agacaaaaag tatgtacctg cattaaatga actcgacgat ttcagtcatt
    20101 taaatgtatt ttggtgggct gatgggtttg ataatcctga actaagaagt attttagaaa
    20161 ccccaaaacc ttataaaagt ggaccagacg ttataggaat atttgcaaca aggtcaccta
    20221 taagacccaa tccaatagca ttgactgctg tacaaattat caatatcgac catgaaaatg
    20281 gtataataaa aataccatat attgatgcta atgataatag tcctgttata gacttaaagc
    20341 catatactcc aagcgttgat agggttgaaa atccgtccat tcctaaatgg tgtagtcact
    20401 ggcctaagag tgtagaaaaa tcaggagaat ttaattggga agatgaaatt gaattttaaa
    20461 ttactttttt cttgatttca ttaacttgtt ttccacattt attttattta cacttaccaa
    20521 gattttatgt cacatata
//
LOCUS       DAMJWC010000065        20247 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMJWC010000065 DAMJWC010000000
VERSION     DAMJWC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20247
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.065"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(32..2143)
                     /locus_tag="PC503_002866"
     CDS             complement(32..2143)
                     /locus_tag="PC503_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2528832.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(2133..2885)
                     /locus_tag="PC503_002867"
     CDS             complement(2133..2885)
                     /locus_tag="PC503_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2528833.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(4081..4257)
                     /locus_tag="PC503_002868"
     CDS             complement(4081..4257)
                     /locus_tag="PC503_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528834.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(4361..4969)
                     /locus_tag="PC503_002869"
     CDS             complement(4361..4969)
                     /locus_tag="PC503_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2528835.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(5068..5892)
                     /locus_tag="PC503_002870"
     CDS             complement(5068..5892)
                     /locus_tag="PC503_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2528836.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(6070..6963)
                     /locus_tag="PC503_002871"
     CDS             complement(6070..6963)
                     /locus_tag="PC503_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2528837.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(7220..7657)
                     /locus_tag="PC503_002872"
     CDS             complement(7220..7657)
                     /locus_tag="PC503_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2528838.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(7914..8063)
                     /locus_tag="PC503_002873"
     CDS             complement(7914..8063)
                     /locus_tag="PC503_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF2528839.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(8076..8306)
                     /locus_tag="PC503_002874"
     CDS             complement(8076..8306)
                     /locus_tag="PC503_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF2528840.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(9165..9386)
                     /locus_tag="PC503_002875"
     CDS             complement(9165..9386)
                     /locus_tag="PC503_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF2528841.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            9966..10223
                     /locus_tag="PC503_002876"
     CDS             9966..10223
                     /locus_tag="PC503_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2528842.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            10692..11930
                     /locus_tag="PC503_002877"
     CDS             10692..11930
                     /locus_tag="PC503_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2528843.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYITYDG
                     SVRERKKYENVRYWNPICEI"
     gene            12854..14155
                     /locus_tag="PC503_002878"
     CDS             12854..14155
                     /locus_tag="PC503_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528844.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            14231..14506
                     /locus_tag="PC503_002879"
     CDS             14231..14506
                     /locus_tag="PC503_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2528845.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            15841..16071
                     /locus_tag="PC503_002880"
     CDS             15841..16071
                     /locus_tag="PC503_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2528846.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            16064..16645
                     /locus_tag="PC503_002881"
     CDS             16064..16645
                     /locus_tag="PC503_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2528847.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(17224..17901)
                     /locus_tag="PC503_002882"
     CDS             complement(17224..17901)
                     /locus_tag="PC503_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2528848.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(18090..19454)
                     /locus_tag="PC503_002883"
     CDS             complement(18090..19454)
                     /locus_tag="PC503_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2528849.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            19582..20103
                     /locus_tag="PC503_002884"
     CDS             19582..20103
                     /locus_tag="PC503_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2528850.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         7675 a         2346 c         3027 g         7199 t
ORIGIN      
        1 tattacttta aaaatctaat aacctttttt attataaaat accaataatt tttttgaatt
       61 tcttataagt taatagatat ataaggtaca tataaacccc acaaatccct ataaaaccta
      121 agtttatcaa aagagcattg acctcactat tgacgattct accatcatta tttaacataa
      181 tcataaaatt aaacagataa attaaaaaac ttcctgcaat aagagggtat gaaaatactt
      241 tctttaattg atttctaata cagaacttta tataatcatt gtttgctcct aatcgattta
      301 aatccataaa gacctgcttg tgatttatag ctatagtaac accccttgta tatgcaatga
      361 ttcctactgc tgtaaaacat atgattgcca catatatgaa taacattaag aagactgcca
      421 tgttttttat catatcttgg ctttgtaaaa ttttaaagtt aggatagtat ttccaattaa
      481 gatacaactg attgttgttt gggtctagtt ttaaatgacc ttcaccactt ggatattctt
      541 catccataaa atattttctt ccagttgatt cataacgttt ttttacgtat tcatcataac
      601 cactgaacat gcccatttcc ttagatgttc tttttataat ttctttcttt aagtcattgg
      661 caaaagcata ggtatcttta tctacattaa atagtataga attattgtaa ttttttatgg
      721 ataaatcttt agtaaatgat ttataatcct cctcattaag gacataggcg ttcatacttc
      781 tattttgaaa aaaagaacca ttaaatatta tttttccagc atatctaaag gggatttctt
      841 tttctgtgac tgggcttgat ataaatttgg tatatttata atcttgattt tcatttcctt
      901 tatttacaac agcaagatat tcaccatttt ttatagttat tggtttgcca attagcttgg
      961 aaaaatcttt ggaattaaag aacatatcat aggagctttt tttcatatat accttttcga
     1021 tagttccatc tttatgatat attgattcta caccatcaac aattaattct atagaaggaa
     1081 tttccatata gttttgaatt tttatattgt gtttatctgc taattgttca atatcttttt
     1141 ttgatacctg tttatctctt tgattgtagg taaaagtata atctataggg ttatttttaa
     1201 gagtatcata gatacctgta accatattag gaacatagaa tacagcaaat aatgctcctg
     1261 caatcaaaaa tgaaataaca cacatgtttt ttactgtttg tcttcccata aatctcatca
     1321 tgctagttga tatgatgttt ttatagtatt tctctggatg ttttcctctt ttagcatgta
     1381 caactatgta tgtcataatc atatatattc caataagaga gagtagataa gtaaagctcc
     1441 atatagatgg tagtttataa tttaatttgt ttatagttag tgaaggtacg agatatccta
     1501 gaaaaatacc gagtataata aaaattatac ctaatatacc ataccagtcc tttacatcct
     1561 gtattggttc agatattctc tggtcattta atatatcaat tatatttgta cgattaataa
     1621 attttacaga aagtataaat atgcataatg tcacaaatac actaaatata aatccatata
     1681 tgaatccttg agttccaaaa tgatatgtca tttctctggt atcaataatc actaattgaa
     1741 atattttcca tataccaaaa gatacaggaa tacttaatat aagacctaaa aaacagcata
     1801 ctattgaaat taacaatatc tctgaaaata gaagtttttt taatttcttc ttatctgttc
     1861 ctagagccat gaaaatacca atttccttgc ttttaaattt taaaaagagg gaagaagcgt
     1921 atgtagtaaa gacagcgcat cctaatatag caactgagaa tatcattgta gcctgttttc
     1981 tgctatctcc accagttgga agtatgtttt gtattgttgg gctaaaataa attagagcat
     2041 atgaagttac taataccaca gaaagtatta tacaaaagaa taaagttgta tagttcttcc
     2101 aattataggc tcgaagttta ctgtataatt tattaattgt catcttgagc gcctcccatt
     2161 tcttttaaaa cttctagtaa ttcatctagg aatttatgtc ttgaatttga ttttacaact
     2221 tctttataaa ttattccatc tttaagcaca ataactcggt cacagaagct tgctgcaaag
     2281 ctatcgtgtg taaccatgag tatagtagca tctaattctt gctttgcttt taaaaatgat
     2341 tcaatgactg tacgacaaga cttactatca aggttaccag ttggttcatc tgctaatatt
     2401 aaatctgggt tgttcatgag tgctcttgct actgctgtac gctgtttttc tccaccagat
     2461 atttcggcag ggtatttttt tctgatatgt tcaataccaa atagctcaca tagattaatt
     2521 gcacggtttt ccatttgtaa gacttgacta cctttgataa tttgtggaac acatatattt
     2581 tcaaagacac taagaccatc aaatagcatg aagtcttgga atacaaatcc tagttgttga
     2641 tttctaactt ctgaaagttc cttttctttt aaatttctta tattattatt tccaagaatt
     2701 atttccccat tatcaattgg gataaaacat gaaatacaat ttaaaagagt agtttttcca
     2761 cttcctgatg aacccatgat tgcgacaaat tctcctttgt tgatttcaaa agaaatattt
     2821 tttaatacag gatatgtttt actgcctgtt ttatatgatt tacataattg gtttacttta
     2881 agcatatata tcatcctcac tttcatttat cttgtaagtc aatgatagca tttgaaaggg
     2941 gaggagggat atgagctata ttgtaatagt tggatgtttt tttgtaatgt ttgaaaatat
     3001 attgtttgga tagtgtgaga ggttattatt atagttaaat tgattatatt attggaggat
     3061 ttagagggtt atttttaggt attaattgtt gtgctaaagt aatatgatgt ggaacattga
     3121 aggtgtaatt agaaaagaag tatatagtaa aagtaaaaag gttatagaat aacgaatgtt
     3181 gtattgaaaa aaatgatgta aataatgtat agtagggtta aaaagaaaaa aagaattata
     3241 gagcagtaag attatttaat ggaatgtatt gtaaataatt tgaaaggatt taggggctat
     3301 taacacaatg taattgagaa aatatattgg agttttggaa ataaataggt tgttagaaac
     3361 aattgaaatg tataataaaa aggttaaaaa gtattattag tataggtatg atagataatt
     3421 ttagaaagtg gaagtatttt agactatgct gaaaagtgat tgatatgatt ttgagatatt
     3481 aaaatattac tatattatag taaagaagtt aaaataataa aatgttgtaa taataaaggt
     3541 ttgtagtata ataaagaact gtaataaata agactttgca atgtaataga aatgctgtaa
     3601 taataaaggt ctgtagtata gcaaagaact gtaataaata agagattgta ataataaaag
     3661 tctgtagtgt aataaagaac tgtaataaat aagactttac aatgtaatag aaatgctgta
     3721 ataataaagg tctgtagtat aataaagaac tgtaataaat aagactttac aatataatag
     3781 aaatgttgca ataacaaaac accataataa ataagagttt gcaatataat agaaacactg
     3841 caataaataa gagatttcaa tataataaaa gtctgtaata taacaaaatc ctataataaa
     3901 taagatttta caatataata aaaatcctat aataaatagg actctgtaat ataataaaat
     3961 gctgtaacaa caaaacacta taataaataa gaccctgtaa tataataaaa atactataat
     4021 atagtaaaaa tcatgcaata ataaaaatct ataataataa acctcagcat aacaaagaca
     4081 ttaatttctt actaaaaagg ccaccacaat taacagtgaa aaagcaattg aaagtattga
     4141 aaaagtaaag tgagaattag agtcattatt acgattatta agttttatcc ataaaccaca
     4201 tataattgta cacaacaata aaattgctga tattactcct ataaatgtaa aaaacattaa
     4261 aattcctccc ccttatttaa tgcaagtatt tttagtcaat gagaatattt tcaaacgtta
     4321 ccataaaata aaaaaatgta cataaaaaat taatatagta ttattttgta atatctacca
     4381 ataataaatc taattgaaaa tctattaaac catttctctg ttcaatatta agaatatcaa
     4441 taccactata cttgaaaaaa gcattagaac gaagaaaaag caactgaata aatgaagtta
     4501 tttgatacgc aatagttctg tattcagctt cagttttttt gttattctga ttttcatagt
     4561 gagccttaat taaaggtagt atctcaaatg gataaacaat ttcttcctgt atcaatatat
     4621 agggtacaga aatctttata aattgactat gttcacctat aaaatcaaaa aatgcaatta
     4681 gtatttccct taattgctgt ttaggtgcta aatttttagt atcatgtgta gccttatatt
     4741 catccatatg acgctttaaa aattttttaa tagaaatatt aattaactcc tctttagatt
     4801 taaaataata attaatcata gctaaattga catttgcttt agctacaatt tctctagccg
     4861 taatgcttga aacatctcta tgtgaagata gtaactggat tgtggcatta attaattgtt
     4921 cctttgttga atctgctttc ataatttttc cccttaaaag tttctccata aaaaaattaa
     4981 acatgtttaa tacacgttta gatactatca tgaaaatttt gggatgtcaa tgggtgatta
     5041 gtacttaagt atttaagtac taatctatta gacttttata agggggattt gaatttctgt
     5101 aagataattt tcaggattta tttcattatg ttcaccttta tgtccgattt gtctatttat
     5161 acctgatatt tgataatcac tatttttatc taaccaataa cagaacgatt catatgcacc
     5221 agctatattt tcatatggac cataaaccat agtacatgcc atcatatcaa tttcttctgt
     5281 ctcacgatat ataaatccag atttgttctt tccaatcttc tttacaacca ttccaacttc
     5341 aatatctaca ccattatctt tgacttcttc atcatggtaa aaagctatgt tattgttgga
     5401 ttgacgtgat acttctatat gttcttcttt gataaattta gatagctttt cccagagtat
     5461 accttcagat tggtagtctg gaattatctc tctaagtgat atgattttat aacttggaat
     5521 ctttttaaag acaacattgt aatgaatttc atctttatca cagtttatag cttctataaa
     5581 tttatcaatt ttatttattc tttgttgttc ctgctttatt tccttttgta tttcattctt
     5641 ttttctattc aattccttaa ttacaaattc atcattccaa ttatgtacga tatttgctat
     5701 ttctgcaacg ctaaattttg aatctctcaa taatacaatt ctttgtaata ttgaaatctg
     5761 ttcaactgag tataatctat gacctgtata tttgtctgtt tttgcaggtt ttaaaatacc
     5821 aagttcatca taataacgca acatacgaat agaaatttgt gttagttttg aaacctctcc
     5881 tattttaaac atgaaaatat gacctccttt tcacttataa tcagtatata ttttgttttt
     5941 atatacttca agcgtttgtg gaaatacaat tattttccag atgttgcaat aaattataga
     6001 gagtaaatta tatttaagta gtaatcgtat caaatcatag attatcttaa tttataattc
     6061 atattaaaat taccagtcta actcaaattc aaaatcatcc gactttatct gttcaatttc
     6121 agaatttacc ttctgtttaa atttattaga agaaatcata tatacaagaa atattaaacc
     6181 aaatattatt tgtacatatt gagctattac acataattta atagggtagt gtagaagtaa
     6241 ttgaatgttg aaaaaatagt acatcatatg aactaatcca gctgataaaa tgcttctact
     6301 tgtattgata tatacaaaat taattataaa gtttaaaagt acaatgtttg gtataaataa
     6361 aaaagcatca aatagggagt attgtgccaa attatatggt atttgattag gtgtaaaata
     6421 cgaccctaga taccagattc cacaaacaag ccctaaaata attgaagagc ctataaatcc
     6481 aaatctaact aataatttgt caatggcata tcctctccat ccagcttctt gactaagtat
     6541 actcaatata aaacttgcta atagcatata agctatttta gaaggtctaa acactgctat
     6601 gtgtatccaa tctatatcag aagtttttac attaaagtaa tttccgatta ttaacgaagt
     6661 aataaaagtt aaagcaaaaa ataatattgt taatagtatc cattttattc cgatttcttt
     6721 aaagcttagg tatctataaa taaaatcttg ttttgcactt tgtggataga ttgtagaaat
     6781 aaaaaataga cctacaatag ctggtgatgt atatgcaaga taaaaaatga tttctccaag
     6841 tattgtattt gtaattccga gcaacgcagg tgtaagactg aatatccagt tcaatactag
     6901 agtaaatgta aagaaataga ttaagtgttt gtttgtatta aagggggtgt tatatagttg
     6961 cattttttca ctatccttcc gttttataat gaagttttaa tttttattaa ttgtttattt
     7021 atttttatat gtattaagtt atcgcttgat gttagttatt gcctataata atatcctatt
     7081 ttttatattt tgattaatta tttttacact aaatataatt aattagtatt taatattgaa
     7141 tatattatat tattattaat tattaaatag gtcaataaat ttgcaattag tgatattaat
     7201 aaattacttt agatttttat taaatgttta gcttttcttt aatatttttt atataacgac
     7261 gatttataat aactttttcg ttgtttttta aagtagcttg catgcgatta tgtgatatta
     7321 cttttatact ttttatgtag tccatattta aaatcatgga tttagatatt cgtgagaaag
     7381 atgtattagc taataatttt gataatttat atatttttaa atcaatttca aatacatcat
     7441 cttcataata agcaaatgtt ttatttccaa ctgtctcaaa gtataaaata tcacagacat
     7501 tgagtttata aatctctcct gattttttac cttttatatc aagtaacggt atactcaata
     7561 atgaaattat tttttcaatg ttattatcta gagcagaaca ttttatggtt atttcaatat
     7621 catcacaatt aataccttgt tcgacatgta ttttcattaa tcatcacctc attttattac
     7681 tgtcattaga atagcattat atcttattga gtccaactag atgcgttcta aatttcaaat
     7741 taagcatagt gaaattcaaa aataaaacag tgaaattcaa atttgaggtg gtaaaattca
     7801 aaaaaatact atggatattt ggataaatta tccaaatatc ctagtatttc acatagaata
     7861 tgtctaatta ttttacaaat agacctattt tatgacttac atatattgtc aaattacttc
     7921 ttaaatatca aaatattttt ggataatgta tcaatactgt ttgataaagt atttaattta
     7981 ccctcaattc taaccaacaa gtacatggat agagctatag gaaaaccaac attggttatt
     8041 aacagttgta aactatcatc cataaaatta gccccctatt ctataactaa gtcataagga
     8101 gtggtatttg tttccacaac cttggcttca acaacagaag ctaggtcaaa tcctccaacc
     8161 gaaaaaatat ttttagatac tatcaaatcc atgacagatt ttatattttc ttcagttaaa
     8221 tcatcctttg gattttctat agaaaaagaa acttgtttat cctttacatt tttaaagctc
     8281 atgactaatt ttttcttaat ttccatataa ttacctccga tataataatt tatattttaa
     8341 ttgtttgctt gttaatattg gtattttaat tatcaatatt aatgttttgc ttgttagtat
     8401 taatatttca attgtcaata ttaatgtttt gcttgttagt attaatattt caattgtcaa
     8461 tattagtgtc ttgcttgtta gtatcagtgt ttcaattgtc aatattagtg ttttgcttgt
     8521 tagtattaat atttcaattg tcaatattag tgttttgctt gttagtatta atatttcaat
     8581 tgtcaatatt agtgtcttgc ttgttagtat taatatttca attgtcaata ttagtgtttt
     8641 gcttgttagt attagtattt caattgtcaa tattagtgtt ttgtttgtta gtatcagtgt
     8701 ttcaattgtc aatattagtg ttttgcttgt tagtattagt atttcaattg tcaatattag
     8761 tgttttgctt gttagtatta gtatttcaat tgtcaatatt aatgttttgc ttgttagtat
     8821 tagtatttca attgtcaata ttagtgtttt gcttgttagt atcagtgttt caattgtcaa
     8881 tattagtatt ttaattgttg actctagtta ttgctgatat agaaaatatt taatttattt
     8941 caattaatta gattaaagta gggtagcatc taaaatagct aacatgttta agttgaaata
     9001 cgtttaatat attaattttt caaagcgtta atatattaaa gttataacca aaattgaagt
     9061 tataatctgc caaatctata gcgtattaag tgcattatat aacttaatct tttatataaa
     9121 gagttaattt tttaatttgt aaagcagagt acgtttaaaa gacactattt agatagtgat
     9181 gtactatcta attttaaaat atctacaata gggttctctt gaagacttgc tattgcttct
     9241 gcaacagcat aaacatcttc atttaatgcc tctgctttta catttgcaaa tgatttactt
     9301 ttaacaactg ccttaccctt atcatcaaaa ccagcatcca attttagttt tatactagat
     9361 aaattttttg ttgaaacaac ttccataaaa ttacctccta aaaatttaat ttcaaagatt
     9421 tgtcgacttt ctttgttagc tataatacta tcatctaaga taatatcgga gttaaacagt
     9481 aatttctaaa gattttttgt gtaaattttt ataggaaaaa ttttactttt ttgctgatga
     9541 aaaagtttac aagttatttg tgaagatatg ttcttagtgt tttgaaatag tatttgtata
     9601 tattcatgct tagttgagat agttttgtat ggattttcat atgtgtagag ttaaatgtta
     9661 ggtactaaag tttatgttaa attaaatgtt aaagcttatg ttaaaaattt tattaaattt
     9721 aatctgtaaa taaaaaagtt aaaagtccaa tattaacatt ttacttttaa accattaaaa
     9781 tctttattaa agctaacaaa gttataagtt atgagaaatt ttattgaagt taatacaaaa
     9841 attaatttta aagctaagaa attttttatt agattcaata aaactaataa atatagttta
     9901 gtcaataatg tattaaataa aaactttgtt aagtctataa aaatatctta aaggaggtgt
     9961 aacttatgaa gataaaagtg gaggatatac cagttcaatt tcatgcaatg gtagaaataa
    10021 tcggaattga taagttcata gaggttgcca agttgtatgg aggaacaaat acttatatac
    10081 ctacgtataa ggggcttttt agatatgcta gaaataggga tatagtaaaa caatttaatg
    10141 gagtcaacca caatgaattg gctattagat ataatatgtg tgtaagcaat attaagcgaa
    10201 tactcaatga aaatagtgtt taaatataat aaaataatgt ttaaacataa tgaaaatagc
    10261 cttgttaaac gtaagagtaa agacaaagaa gatgttttat aaagtttttt tagacaaatt
    10321 aactaaattt actacttatt aatttaaata cattgtatat tctataaaaa aatttgttaa
    10381 atactggaga tatattgaga atacaaagaa aatggtcgaa aatatttgtt ggctaaaaaa
    10441 tagataaaat gatacaattg cttgtataaa ggggaaaaat aaataaataa actatataaa
    10501 taaagaaata gcaattaata tgacataata tatttataaa attaagaata taaatagata
    10561 ttttaaggga ttagttgtta aattaggaaa tattaaaaaa aatatatatt tatatttaaa
    10621 ctattttgtt atttatataa aaatacttat ctagttacta gcaattatta gtagaaatgg
    10681 gggaaataga gatgaataag ggattttaca aattaaattc agtggtattg aactttgata
    10741 ttaagaatga tgttaacaag ataagattta atcattatat aatgagaaaa gaaaacatac
    10801 aaagacttca aggaactctg ccaaacggac aattttatat gacagtgaga agagctgcta
    10861 cagatttaca actttctatt tctactataa gtaggcttgt aaaagagttt ttggatttag
    10921 ggataataag attagtgtct aagggtgtaa aaggtaatcg ttctgtatat agttacgtaa
    10981 gtatagagtt taatggaagt ttatttgatg atagtaaata tatggaactt gactgtgtat
    11041 gtaatgatga atttattgat aatagtggca tagagtttga ttgtgatagc aaagataatt
    11101 cttttaatgg agatataaat gtagaaactg tgcattgcat taatgagtat ttctctgatg
    11161 atgatgtaga gcataattat aacaatttcc ataacaaaga tactataaag gataaagcca
    11221 tttctaatat tagcactatc aaaaaatata ttgatgaatc ttttgataca aataaatcag
    11281 aaaattctaa cttacaacag gagtcaataa atttcaactt taatgataca tgcaatgaaa
    11341 tagataaaag aacgaataat agtatagaaa ataatcaaaa taaaaggcct atgagattga
    11401 gtgacatcag tcttttaagt gataaaggta tgacaaataa aaagaattac tttaatcata
    11461 atcatggtat acaaaaaggg actaaatctg taacaaagaa aaaagaatcc ttaaataaat
    11521 ttaataaaaa aaatatacag caaagcatta taaatatgct aaataaaaaa tcaggtaaga
    11581 attttaaaat cgattctcca ataagcataa aacttatcaa tgaaaggcta aaggaaggct
    11641 atgtcttaga agatttctac aaagttattg aggtaaaagt ggctaagtgg aaaaatacca
    11701 taatggaaat gtatataaga ccagaaactt tgtttagcta taagtttgaa tcctatgtaa
    11761 atgaaaacat atctatgaaa agtcaaagta atgttcaccc atgtaaagaa ggcaatagta
    11821 atgatagcag taattatata cattctgatt atataacata tgatggcagt gtgcgtgaga
    11881 gaaaaaaata tgagaatgta agatactgga atcctatatg tgaaatttaa ttagtttaaa
    11941 aatgtattta tgataaataa gatattaata gagaatagtg agctatagca aatgatatat
    12001 caatagttgg tagtaagtta tattaagtaa gatattacta tcaggtagtg aattatattg
    12061 aacgatatat taataattgg cagtaagtta tatcaaataa gatattacta tagagtaatg
    12121 aattatattg aacgatatat taataattgg cagtaaatta tattaaataa gatattacta
    12181 tagagtaatg aattatattg gacgatatat caatagttgg tagtaagtta tattaagcaa
    12241 gatattacta tcaggtagtg aattatattg aacgatatat caataattgg tagtaaatta
    12301 tattaagtaa gatattacta tcaggtagtg aattatattg aacgatatat taataattgg
    12361 cagtaaatta tattaaataa gatattaata ttggatagtg aattatagtg gacgatatat
    12421 caataattgg tagtaaatta tattaagtaa gatattacta tcaggtagtg aattatattg
    12481 aacgatatat taataattgg cagtaaatta tattaaataa gatattaata tcgagtaatg
    12541 aattatattg aacgatatat caataattgg cagtaagtta tatcaaataa gatattacta
    12601 tcgagtaatg aattatattg aacaatatat taataattgg cagtaagtta tatcaaataa
    12661 gatattgcta ttatgtagta aattatataa aacaatgtat cagaataaat agtatattaa
    12721 taatttgtag tatatcatga cgaataatac agtcataaca aatagtgagt cataacaaat
    12781 aatgtattta taattgataa tgtatttaaa aatcaaaata taaaaactta taaggaaaga
    12841 gagattaatt tatatgggta aatcaaaaga tgttgaaata gagaagtcta ttttaggcac
    12901 aattctttta gacaataaat taagctataa gctagatgaa ttaaatgaaa acatgtttat
    12961 gaatgatata tgtcttgaga tatttaaaat tatgaaagaa cttaaaaaag aaaacatagt
    13021 gattgatgtg gccactgtga aatcaaagat agatagaaaa tctctagcaa taaaaacaag
    13081 tgatgtgact aatctaatta cttggggtca gaattttggt cttgatggtc atattaaaat
    13141 tttaaaagaa aatttagcta gaagaagcat aaatcaaaac tgccaaaacc ttttacacag
    13201 cctaaacctt ggagaaaata tcgatacttg tatttacaaa tttgaaagta atataaagga
    13261 gattttggac aaggatactt atgaaaatga tgatgtaaat agtatagcag ggaaggtgct
    13321 tgatttttta gaaaacaaaa aagatattgg atttaaattt ggtataaaat tacttgatac
    13381 cactatagga ggtcttttta aaggagagct aaccacaata gcagctaaat cgggggttgg
    13441 gaagactgct ttggcacttc aaataatgtt aaattcattt aagcaaggta aaaaaacttt
    13501 atttataagt agagaaatga ccagtgagca agtatttatg agaaatatat gcagagtaac
    13561 tggtgtaagt acaaggaata tgaaatctaa agaaatagat gaaaatgatt ggaaacttat
    13621 tgtaaatgcg ataggtgatt taagcgaaaa taacttaatt tatatcaatg ataagataga
    13681 tacaattagt gcaattagaa agaggataag gcaggtaaag ccagatttat taatagtgga
    13741 ttatgtgcaa ctccttacat ctcagaaaag catggataag agagaaaggg aggtagctac
    13801 tttttcgaga gaacttaaaa atatgacttt agattttaat atacctgtaa tccaattaag
    13861 tcagttaaat gatgaaatga aagattcaag accttatgga gatagaccta tgagggatag
    13921 caaagccatc taccacgata gcaacaatgt ggtttatata catcaattaa aggggagtga
    13981 ttatgaagaa gcagtgagag atattggaga aagtgaggag gcagttagag catcagaata
    14041 caggggaatt aagatggttg atttaatagt tgcgaagtgt agagatggac agactaggca
    14101 taagcatttt tgttactttg gggataagtt acattttcaa gaactaaatt attaggtcaa
    14161 taaagtagta ataacaagct tattaaaagt cgggaaatag caaatagatt ataaaatatg
    14221 aggtgaaaat atgttggaat taagaaaaat tatagaatta cttgaagaac acaagataga
    14281 agtaagtatt ccaaaggagt tacataagta tagtttattg gaataccttg aattgtgtca
    14341 acaaagtggg ggaacatatt tttatattaa aacactggaa ggggctttaa aagaggctag
    14401 aaatgagctt atgattaaat tgtttaatgg gaaaaattat atggaattag cgaggatgtt
    14461 tgaaatgagt gttattaatg tcaggcatat tgttagaaaa aaatagatat ttttggagaa
    14521 tacaagtgtg atatacttct gaaatagaag ttattataag aggagtataa gtgtgattaa
    14581 caacatgatt ttgtgaataa aattgaggat atatatgagt taaatgtgtg attaataagg
    14641 taagattgtg tataagatta tgagtattta aaaggagggg ctataattaa tagtgtagag
    14701 ttgtgtgttt gcttaagatt atataataat ttaatagatt aaactatact aataaggtaa
    14761 aatcgtgtgt ttagttaaag cttattataa aatcttgata tgtgattaat gatgcaatat
    14821 gtgaataaag ttaagattat aatagattta acctgtggct aatagaataa aattgtgaat
    14881 aaagttaaga ttataatagg tttaaattgt gactaataga gtaagagtgt aaatagagat
    14941 aaacttcaat atgagcttaa cctatgatta atagagtaag aatgtaaata gagataaact
    15001 tcaatatgag tttaacttgt ggctaataga gtaagagtgt aaatagagat aaacttcaat
    15061 atgggtttaa cttgtggtta atagagtaag gtgtaactaa agataaactt caatatgagc
    15121 ttaacctatg attaatagag taagaatgta aatagagata aacttcaata tgagtttaac
    15181 ttgtggctaa tagagtaaga gtgtaactaa agataaactt caatatgggt ttaacttgtg
    15241 gttaatagag taagaatgta aatagagata aacttcaata tgagcttaac ttgtgattaa
    15301 tagagtaaga gtgtaaatag agataaactt caatatggga ttaacttgtg attaatagag
    15361 taagagtgta actaaagata aacttcaata tgagcttaac ctatgattaa tagagtaaga
    15421 atgtaaatag agataaactt caatatgggt ttaacctgtg gttaatagag tagggtgtaa
    15481 ctaaagataa acttcaatat gagtttaact tgtggctaat agaataagat tgtgaataaa
    15541 gttatagttt tagatgggta ttaacctgtt actaatagaa tatgattagg tgtaaaatta
    15601 tagagctgca taagaaaata ttatagatat attaaatatt agataataaa tatttatata
    15661 gatacacaaa agaaaaggcg atatgaagct aaacttaatg acttcatatc gttttttatt
    15721 tgaaactcct ttgtatttag agtgtgattt ttaatattga ggttttatgt gattaagtca
    15781 cagataaaaa gtaagtatct tgatataatt cttatagatt aataatatag ggaggttatt
    15841 atgtctaata aaaaaaagaa gtatgcaaat attttagcaa atgagtgcgt tgcttgtggt
    15901 agctgtataa aagcatgtcc aagaagtgct atctcagttc catgtggcat tagtgcaaaa
    15961 attaatagag atttatgtgt tggatgtggg atttgtgaaa agatatgtcc agcatctgta
    16021 attgagatta taacaatatt aaaagaggaa gaaggtaagt gtcatgaata ataaaaaaca
    16081 ttggtatgac tatttatgga ttttttcttc aatatatttg atattgggat ttgtaaatat
    16141 tattttcgct tggattgggc taatttgttt ctttgttcca ctagctattt ctattgttaa
    16201 gggaaataaa gcttactgta ataagtattg tggaagaggg caactgttta atttgcttgg
    16261 aaataaattg aagctgtcaa gaaatagaga tattcctaaa tttattagaa gtaagtggtt
    16321 tagatatggg tttttgacat tttttatggt aatgtttgcc aatatgcttt tttcaactta
    16381 tttagtgttt gaaggaagta gaaattttaa agaagtagtg actttgttgt ggactataaa
    16441 aatgccttgg caatgggcgt atcatggaac tttagtttca ccttgggtgg tacagtttgc
    16501 atttggtttt tatagtgtta tgcttacatc aactgttctt ggtttgatta ctatgatatt
    16561 gtttaaacct cgttcatggt gtgtttattg ccctatgggt actatgactc agatgatatg
    16621 taaggcaaag agtaagtctg tatagaaagg ccttatgtga tatttacagt tttgttcaag
    16681 tagagatgag tagtaggttt gaatatatat gacaaatata tgagtatagg ggcatagatt
    16741 tagtttgtgt aaggtaaact gatttatgct tcttttttat gtcttagatt attggctaag
    16801 tggaaacaat gaatttagat attaagaatt attcagttat ttgaagaaaa tagaataata
    16861 attaacatta tattaatgga tattcattac atataagcca gttaatagca agatttattt
    16921 aatatgatat aggtcaagta tttaaactaa ataaggtcat gacaattaat ataagtatag
    16981 atataaaaag attagaagtt ataacttata aaaggtattc tatataaata gtatggggaa
    17041 aatagtcaaa ttaacttatt agaaacaaaa aatatacata aaaaataaat gtaaatatca
    17101 aataagatac tatatcaaaa tagatataag tatctttttt attattgaaa ttatgaaaat
    17161 atatttgatt ttacacaaaa aagagtgcct catgaactaa aaagttcatt ttgagacaca
    17221 cttttacagt gtcaaagaac gaagtttatc cttatccaat acctttatac caccacgaga
    17281 taaagacaca ataccttctc tagcaaaata tttcaacatt ctcgatacaa cttctctggc
    17341 actacccata tacttagcaa tttgctcatg agtcatattt atagtgctac tgccattttt
    17401 agctatctca tcaattaaaa aagatgccaa acgcttatca aaactcataa aaagaatttg
    17461 ttgcatagcc cacataacat cagaaaaacg ttcagtagct aatttatatg aaaataactc
    17521 tgcatgaata ttttctgtag ataattttgc aaaaacagag gaactaatct gtataatatc
    17581 gcagtccgtt tcagcatcta catagacatc aaaagttatt gtttttagaa tacaggaagc
    17641 tgataaaata catacatctc catcatcaag tcggaacagt gtaacctctc gaccttcatc
    17701 tgaaagtatg tatgtacgca ctgttccaga ttttataatc aaaataccaa tacagtcact
    17761 atcaccacaa tgtactggat tccctttttt gtaatgcgag gtatttgctg aagaaattaa
    17821 taattctttt tgtaagtcag taagtttatc ccaaaaaggc aagctatgtg taagtatatc
    17881 aatttcattt tgtgaaatca tacaatatct cctttcttaa attgttataa tcccatgata
    17941 caagtgaata gataaattga caagtagttt gttaagagga ttatttagtc agatagtaat
    18001 agtatgattt atgtagaaaa aatatgataa tatatattct tgctattaat gagaaagtaa
    18061 tatgttttga tgatagtagg tttgtataac taatgcatac cgtttatttt taaaagatta
    18121 agttccttat gtaaccttat agacataaaa ccagcaatta tagcagccat caaatcagct
    18181 attggttgtg catataagat accatttaac ccatagaata caggaataat caaaattata
    18241 gggataaaac agacaccttg tctacacata cctaaaaatc caccttcctt tgcttttcct
    18301 agtgcgagga ataatgtaga atacactgta tagaatccaa atagcataaa tgaaaaccca
    18361 tttgccctaa gagctttact accattttct attaataaaa tgtcaccact tgtaaattgt
    18421 gaaattatag attttgggaa gagtatcaat ataagaccaa gcactacaca aaatactgta
    18481 gtccataata tggaagtttt tattgctata tgtaatctat cgtagttctt tgaaccaaaa
    18541 ttataaccag caattggttg gaaacctttt ataaaaccaa atacaacaag actacctaaa
    18601 gacgttattc gtgttacagc acccattcca gctatcacag aatcaccata ctttgtagcc
    18661 tccatattag ttaatgtaat agcaagacta gtcaataatt gaaatattaa ggtaggtatg
    18721 ccaattttta ggatttctga aaaaatttct tttgaaaaac agcattcgtt aattctaaaa
    18781 ctaaatatac ttttcttgct taaaatatat cctacataaa caagtgttga agcaatctgt
    18841 gagatagctg ttgcaataga agcacccctt acccccagac caaaagtata aatgaatatc
    18901 gggtctaaaa tcatattaag caaagcacct aataacatag cacacatagt tgttttagca
    18961 gctccttcac ttgtgacaat attagtcata gtgacattga atatattaaa aatagatgac
    19021 acgacataaa tgctagcata agatattgca taaggcataa tactttttgt agctcctaac
    19081 aattttaaaa ttggattgag aaaaatcata atcacaataa taactaatgt acccactata
    19141 atactactgt aaatagatgt acttaccact tttcctgctt tttcattatc accatggcct
    19201 aaaagtctgg caacatatga agcagctcca tttccaaaca ataatcctaa tcccacaaca
    19261 agctgaccta atggaaatgc aacggatata gctcccattt gacttgttcc aagtccaccc
    19321 acaaagtatg catcaaccaa attgtataat gcagttatca tcatacctat catggtaggt
    19381 aatcccatag ataacaatgc ttttgagatt ggggcagacc ctaataattc aattcttttg
    19441 ttactttctt tcatacttaa cactcctctt ctattgacat taagtctaaa ttataatact
    19501 ataaattata gtaagtatgg aaaatagtac tataatttat agtatttgtc aatagtaaga
    19561 aaactaaagg agatgatttt tatggctaca atagatttaa ttgtattggg aatagtaaag
    19621 caacaaccca agagtgctta tgatattcaa aaggcagtgg aatacaggaa tatatcacgt
    19681 tgggttaaaa taagtacacc atcaatttat aaaaaagtaa ttcaattaga acaaaaggga
    19741 tatattgaaa gtaaaactgt gaagaatgga aaaatgccag aaaaagcagt ttattcatta
    19801 actgaattag gtgagacaca ttttttagat ttaatgtttg atacatctag caaaccaata
    19861 aatattcttt tagattttaa tgctgttata gtaaatttaa atagccttac accagaaaaa
    19921 cagaaattat gtctcaataa tattgaagag aatgttcaag agttaaagaa aactattgag
    19981 gaaaatataa gtataaagac agaagtacca gacacagcaa aagcagtgtt ggagcaacag
    20041 ttggtgctag cacaagcatt ggaaacctgg ataaattctt taaaagataa tatgggaaat
    20101 tagaattaga gaagctaact taataatcat taaacaaaaa ccagcatatt taataatgag
    20161 atattagaaa aaataaaaca aatgatataa actgaaaagt atatttaaaa taaagctcac
    20221 ttaattgagg gagaatgtta aactttt
//
LOCUS       DAMJWC010000066        19769 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMJWC010000066 DAMJWC010000000
VERSION     DAMJWC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.066"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            402..1805
                     /locus_tag="PC503_002885"
     CDS             402..1805
                     /locus_tag="PC503_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528851.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2282..3304)
                     /locus_tag="PC503_002886"
     CDS             complement(2282..3304)
                     /locus_tag="PC503_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2528852.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(3339..4937)
                     /locus_tag="PC503_002887"
     CDS             complement(3339..4937)
                     /locus_tag="PC503_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2528853.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4979..6244)
                     /locus_tag="PC503_002888"
     CDS             complement(4979..6244)
                     /locus_tag="PC503_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528854.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAE
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6386..7813)
                     /locus_tag="PC503_002889"
     CDS             complement(6386..7813)
                     /locus_tag="PC503_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF2528855.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLFASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQIYMGVEE"
     gene            complement(7851..8858)
                     /locus_tag="PC503_002890"
     CDS             complement(7851..8858)
                     /locus_tag="PC503_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2528856.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            complement(9055..10377)
                     /locus_tag="PC503_002891"
     CDS             complement(9055..10377)
                     /locus_tag="PC503_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528857.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            complement(10735..12375)
                     /locus_tag="PC503_002892"
     CDS             complement(10735..12375)
                     /locus_tag="PC503_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2528858.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            complement(12531..13187)
                     /locus_tag="PC503_002893"
     CDS             complement(12531..13187)
                     /locus_tag="PC503_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528859.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            complement(13213..13914)
                     /locus_tag="PC503_002894"
     CDS             complement(13213..13914)
                     /locus_tag="PC503_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2528860.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            14722..15201
                     /locus_tag="PC503_002895"
     CDS             14722..15201
                     /locus_tag="PC503_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2528861.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            15198..15977
                     /locus_tag="PC503_002896"
     CDS             15198..15977
                     /locus_tag="PC503_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528862.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFIPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(16227..16727)
                     /locus_tag="PC503_002897"
     CDS             complement(16227..16727)
                     /locus_tag="PC503_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2528863.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(17339..18046)
                     /locus_tag="PC503_002898"
     CDS             complement(17339..18046)
                     /locus_tag="PC503_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2528864.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            complement(18849..19718)
                     /locus_tag="PC503_002899"
     CDS             complement(18849..19718)
                     /locus_tag="PC503_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2528865.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT         6892 a         3489 c         2244 g         7144 t
ORIGIN      
        1 aacaaatcct ataattatat tctaatatac tacctactac tttgcgctac aacaatttct
       61 ctatttatat gatttgtaaa atatagtaca acatttttta tcattttcat ttcaactaaa
      121 tttgtaatat tttattcaat acttaataaa tacttaatca atacatgctt tataatactt
      181 tactcaatat ataatcaata cataatttat aatttgtaat actttattca atacataagt
      241 agaaatctct atatacataa attcattttt tcatacatct tacaaattta tttttattta
      301 gataacatgt atattttttc catgaaaaat aaataataaa aaatagtaaa tatggaaaat
      361 ataaaattga ttaacaataa ttaattacct gaggtgtgaa tatgaaaatg ctaaacaact
      421 tttttaagaa aatcaacaat ccagctcctg tctttgcaca gacaaaaatg gaaagagata
      481 atcaaacaga tgattcactt tctacaaaac caaagactac atttagagac gttgctggat
      541 tagacgaagt aaaagaagaa ctatttgaaa tagtcgattt tatgaagtca ccacaaaaat
      601 atcaaaaaat gggtgcaaaa atacctaaag gagtattatt ttatggtcct ccaggaacag
      661 gtaaaaccct acttgcatct gctgtagctg gtgaaacaaa ctcatcattt ttcaatgtta
      721 ctggttcaga gttcgttgaa aaatatgtag gtgtgggagc aaaaagagtt agaactctat
      781 ttgaaaaagc tagaaaagaa gctccaagta taatatttat agacgaaata gatgctgtag
      841 gagcaaagag acatcttgaa agtaacaacg aaaaagacca aacactaaac caacttttag
      901 ttgaaatgga tggatttaat aaagattcca atgtattaat aataggtgct accaatagac
      961 ttgacttatt agatgaagct ttacttagac caggaagatt tgacagacac attcatatag
     1021 gtgcaccaaa ctatcacact agatttgaaa ttctaaaggt acatacagat gacaaaccta
     1081 tagacaaatc tgtaaatcta gaacttttag ctaaaaaaac tcatggtttc aatggggctc
     1141 atctttcaaa tatagcaaat gaagcagcta tatttgcagt tagagatgac agtgagtgta
     1201 ttacatcaga acattttgac aaggcacttg aaagagttat tgcagggcta gaatctaaaa
     1261 actctgcatt ggttgaaaaa gagaaaaaaa tagtagcata tcatgaagct ggacatgctc
     1321 ttgtaagtga tatagtagga atttgtccta tacaaaaaat atctatagtt cctagaggac
     1381 aagcattagg ttatgttctt caattacctg atgaagatag atatatttat actaaggatg
     1441 agttgattgg aaaaataaaa atattacttg ctggaaaggc ttcagaagaa ttaatattta
     1501 atcataaatc tactggtgca aaggacgact taaagaaagt cactgaaata gctaaccaaa
     1561 tggtttgtga atatggtatg agtaacttag gatttatgac tattgatgga aatgataaga
     1621 ctttcttatg tgataaggtt caaaaggaag caaatcgtat agttgaaatt tgttataaag
     1681 agactttaga gatgttaaag gataatcttg aagatttaca ttctgtttct aaattcttat
     1741 ttgaaaaaga aactatgact catgaagagt taaaagattt gataggaaaa gaagctgtaa
     1801 actaatatag ttttaaaaat ttgaggctgt ctcaaaatag agataagcct ctttttattg
     1861 ttaaagttat aaaaatacat ttgattttat acaaaaaagt gcctcataaa ctaaaaattt
     1921 cattttgaga cacttacata ttttaattac atattttaat tttgtctatt tacagaatat
     1981 tatatctaca taaaactaaa ctgctgtaaa cttaactacc tccagtaatg tttgaagtgg
     2041 tataaaagct agtagcctag tttctacact tataatttat attttacata actaaattta
     2101 gtagattttt atactcacaa tttagaacga ttgaaaactt aaaaatttct tatcagatat
     2161 ctacaactta attaggtatc tatcacttga ttaaatatct atcacttaat taggtatcta
     2221 tcacttgatt aaatatctgc catttaatta aatatctacc acttaattaa atatctacca
     2281 cttaaagtgt agaacctctt tcaatcaatt caggttttaa catttcaacg actgactctg
     2341 gattttcttc atttaataag gacttaagta tgttaattgt tttttcaatc aacaaatcta
     2401 gtggctgtct aatcgtcgtt aaattataac tcttccatga agccatttga atatcatcat
     2461 atcctatcac tgataaatcc tctggcaccc tcaacttgta ctcaaacctt gcagcatcca
     2521 ttacaccaat agctatcaag tcacttgtgc aaaaaattgc tgttggagga tttgataatg
     2581 ctaacattct cttacctgct tcatatccag aatcataatc atagtttgca gattcttctt
     2641 taaggttatg aatcccactt tgtcttaact tagagtaaaa tccaattttc ttttccattt
     2701 cttcacttgt ttctctcgta aattgaatat atcctatatt cttatgacct ttcttaagca
     2761 gatattcagc agccattccc ccaccttcaa ttgggtctac atagactgta cttattttta
     2821 taccaggtat aaaacgatta aaaagaatca caggaatatt gttttcttca caagtctcag
     2881 ccatcacctt attcatggcc gaagctgtaa taatcacagc ttctacttga aactgaatta
     2941 cttttgaaat tatactatct atactttgtt gtctaggaac tttaaaaacg agacactgtt
     3001 tacctatctc ttgaattttt tctacaaata aattgataat tctattgtaa aatggaccta
     3061 gactatcacc aactatcaat cctataacat tagtttttcc actaatcatt ccccgtgcta
     3121 ccaaattagg aacatatcct atttcatttg ctacacgaaa aattctttct cttacttcag
     3181 gttttacgcc ctttccattt gcactaccaa atgctcttga aacagatgat tgagatactc
     3241 ctgccaatct tgcaacatct tttgaggtag ccgatttatt ataatgaact ttcttttgat
     3301 tcatttagta tttctcctta aatatctagt atttcttctt aaaattgtat caaaaataat
     3361 ataatatatt ggataataaa aaaagctaat acaattaatt cttgtttacc taaagaaaat
     3421 ggcactatag atactccatc tactttatcc attccttgag aaataaggtg atttctcata
     3481 ccaaatgcag tgtatttttt aatatcatct gcattatgat ttttctttaa aatgacacta
     3541 aaaatatatc caaatatcaa tgttattgta gcacctattg ctggattcca caaccaactc
     3601 acattatatt tattagaaat aaaaaatcct aaaactaacc ctacaataaa accaatagat
     3661 actcctttat cattagcttt atatgtaaac attgctagta caaatgcacc tgtagctggt
     3721 ccagcaaagt atgagatata gttaccaaca aggtcaagaa ttgatttgat gcttcctcca
     3781 aatcccataa taataaaacc tgtcataaca actcctataa ctacagttat aatcattgta
     3841 acttttaatg atgattcttt gttatctttt ttgaaataaa actcataaat atccttcgta
     3901 aaaacagttg tcatactgtt taatatagag tcgatactag acattgctgc tgcaaacaca
     3961 cctgcaataa taattccaat ggctcctact ggaagttcat ttaaaataaa agtaatcatt
     4021 atttcatttg aagtttcaaa tgtccttccc ccataaaaaa caaataaaat tactcctacc
     4081 aatagcataa agtagtaaac taaattcata acaaatgcac taactacaaa agaatttttt
     4141 gcacatttta aagatttaga tgttaaaact ctttgtactt gagattggtc aaaacaaaag
     4201 tatcttatcc acattacagt tccaccaatt aaagtagccc aaaaagtatt tgtcactgaa
     4261 atatccctac tgaaatcaaa tgtatttaat tttccactct gttgtgcaat ttgtaatgta
     4321 tcaaagaaac ttagattcat tccttttaag gctacaataa ttactataaa tacagcactt
     4381 attactacta tcatttgaat actatcagtc catataactg ccttaatccc acctaataga
     4441 gtgtatataa ttgatacaag tacaactatt gggactaaag cataaagtga ccagccagta
     4501 atcatttgaa taataagcac tggaatatat accatagaac tagcttgaat caatgaatta
     4561 ataaaaaatt gaataatagt taatcctctt gaataatttc ctaaacgaag tcccatatat
     4621 tcatatatag aggttatttt taatttatag ataactgggg tggtaatgct cagtgcaaaa
     4681 aatattgcta aaggtactgt aatattaacc attactggat acattccatc tacatatgcc
     4741 catccaggac cacctataaa gccatttgca ctaatcatag tagctgcaac tgataaagca
     4801 attggaatcc atggcattga cctacctgcc aagaaataat cttcttgatt tttattatct
     4861 tttcctgaat aataaccaat aactaacatt aatagcaaat atcctattat aatacataca
     4921 tcaattgatg aaatcataag ccaccccttt ctaagtaaca aaataaattc ctagtatttt
     4981 attttttatt atttaacgtc tctggtaaga ataaccatac aatagcacct gctacaaaga
     5041 ctgcgattga tatgtaaaag atagtcatca tacctaaagt accagaagct gtaccagcta
     5101 tagcaggtat tgcaaacgta gatataatcc ttcctccatt aaatgacata ccagatgaca
     5161 acgaacgata tttacttggg aacaactctg tgtagtatgc tccccatgct ccagaatatc
     5221 caacagcaac acctagtaat actgatatca tatagaatgt tgttgtatta tctccaccta
     5281 attttgtata tataaaaaca aatactgctg ctaatgccat acctataaaa ggtatttttc
     5341 ttccaaattt atctgcaatt gaaccccaga ataaatatcc tactaattga ccaattcctt
     5401 gtaaactata tatagactca gccactgctg ctgacattcc tattcctgtc actaggtatg
     5461 tagttgcatt atttgaaaat gctgaatatg ctgtaaaatt tgcacctgat aaaagaatcg
     5521 ttcccaatcc aatccataag tattttccct tatacatact tatatagcta atcttttcac
     5581 cagtttcttt tcccttttta actaattcct ttgtatactc caaatcatct ggcacaaaga
     5641 agattgctaa gatagctcca actataggtg gtataatcgc agtatacatc aatatttgcc
     5701 aatttgcatc acctaaaacg ccatatactt tcccaccaaa aatcattgct aatgaaaata
     5761 aagcagttaa tatagcagct aacttaccac gatatttact tggaaacata tctgcaacta
     5821 aaggcatagc tgttccaaat acgcctccca acactactcc tgtacacaaa cgtgctattt
     5881 tccataacat aatatttgta ggagataaca ttggtataaa tgttgtcaat ccaatcagta
     5941 aagcaacgct aattaaagtc ctcttcttcc caatttttgt agaaatcacc ccaaaaataa
     6001 atgtacctgg aattgtacca aaagacataa ctgcaaatat ttcttctgtt tgttttaatg
     6061 aaaaaccaaa tcccccatct gctaaagcat aaatcattgt tggtttaata aaagtaccca
     6121 ccataaaatt gtagcaataa aaaaagtata ttaaagcaat tgaaaaaaat gcaattcctc
     6181 tttttaggtt tgaatagtct tttcctaata tgatatcatt ttctatttca accgttgttt
     6241 tcatattttt ataattcccc cttttaaatt tagtcataat tttgctaaaa gtttaaacat
     6301 ctatttttca tatacattcc ccacttaaat tttataaagc aatacttccc tatatatttc
     6361 aaaactattt atactctaaa cagctttatt cttctactcc catataaatt tgttttaata
     6421 catccatacc atcaaaagtt atccactcct cctttacttt accttgtagt atatgataat
     6481 gattgattcc cattacttct atatgctttc cagaaggctg tccaaaaaat cctatacctt
     6541 catttattcc acgtaatctc catcttacag atacatcata accttcattt ttttctcttt
     6601 gattacaagt tactctttcc acttcataac ttccatttgg aattgatgca aataaactta
     6661 caatcattcc ttgaatctca tcatagccat ttaaatcttt atcacatata aaatgtacta
     6721 ctgcattatc atgatagtat tttttaactt catttatata tttataatta taaatacggc
     6781 ttgtcatttc aagcatcatt tcgccaacag aatcatcttt tgcttgatac ttagttggca
     6841 taaattgacc atccatagat tcacagatac cataagttga ttgtaaacta agcactttag
     6901 attcacttgc ctttgccata ctctttgcta cttcctgagg gtttaatcct aattgagtaa
     6961 caatccataa attatctcta accaaccatt cttcatggat tctattgtta gttgtggcac
     7021 aatcaattac agttctaaag tttatttttc tacctgttgc tggtccaaaa ttactatcac
     7081 ctaagttagt tgctgtagac aaaacacggt gagaagataa aaaaccatca gcaccaaagt
     7141 tagaccatat tacattttga ccaattaatc ttctatcagg aaacgcatgt aatgtttgaa
     7201 gagtattgga aataacatct ttaataccaa ctaaatttga agagccacaa tgcattgtaa
     7261 cattattgtg atatgtatca taaataacac ctataccttt ttcttcccag atattatgtg
     7321 taatcttcat aatataatct acaaaatctc tatacttaga atcaaatcca ggtatttcct
     7381 gttccctttt tgtctgtttt gaaaaatcat tgtaatccat tactccaaca ggcgttactt
     7441 ctaatgaatc tccatagtaa atttttgtag atgacatatt atcttccccc ttaaatataa
     7501 cttttttatt tttttcagta agagtatttg tatttaattt atctgtatcc actgtatcta
     7561 tgttaacttt atttatgtcg gatttatttg tgtttgtttt atctatattc cctttatcta
     7621 tatttccttt atctatattt cttttatatg tgttcgtttt attctcattt gtttgatttt
     7681 catttatatt actaaaatta gtttgattca ttttagcttt gttttcttta accgtacatg
     7741 attcaagccc acttgtagaa acttcttttt cttcctcttt acttgttgca ttatttttgt
     7801 tggtagatgc cactttatat ccccctttgt tttagaatac gtatgcataa ctaagcatta
     7861 aaaatacttt tagttctctc aagaatatca agcccttgtt gtttcaacca ataaggaata
     7921 tcaattaaca cccagttttc ttgaagttta tcgcccttac gataataaac atcaacaact
     7981 tgcatatctg ctttaacctc tccacctggt aatcctaaaa aacctccaca tggtacatta
     8041 gtcagattag gccatccaaa gaaacaagca aaattacctt ctgcaaatct acatacatgc
     8101 ccattaaaag tctttccttt taaattattt ctaaatggta gctggtgttg ctcttgatat
     8161 ctaggtatag tataagaagc accaattcca cctggaccat accaaatcat atctttagcc
     8221 caagattttt caagtatttc tggtgggcat cccatagcac cactttcatt tagttcagat
     8281 aaatcatcta ccattttatt tactaatgct aaagttttta ctccttcaac ttcatctgca
     8341 tcttcaaaaa gtaatccatt atggtcaatt ggccctggat atacaaaata tgaacctgtt
     8401 tgtggtggca atggattaac tcctgcttga atcataaacc caattatatc tacaaataat
     8461 ccagttttag caattttacc atcttgaaca cagttaaatt ctgcatatct taaactaatc
     8521 attttacgag tatgtttaat gccaagccaa tcgttatcaa aaagtcccat aaaatgcccc
     8581 atactcatta cccattcact attgtcaatc tcatttgttc ctgcaatgaa aatatcttgt
     8641 cgtctttgca tattactcaa tgattttttt aaaggcttcc aaaatacatc tgctacattt
     8701 tcagtgcctt cttgttcacg aaatggatac acacctttcc agttataatc tgatttcata
     8761 tgttgcttta agacattttc aacctcatcc ccagtagcat tttctaatgc ttcaaaataa
     8821 tttcttacaa ctttttttga atcctgatat tttcccataa ttatctcctc ccagatttat
     8881 ttaagttata aattaacttt ctcatttcat gcatacgatt tcctttttaa tgatttttta
     8941 gctgttttaa gtttatttta tgaatacata tgcatttttc taaatattaa catatatcta
     9001 aaaaattgta aagaaaatgt tatcataaaa atttaatttt tgacttatat ctatttaaaa
     9061 caacagaaaa ggtttaaaac gtaatattct actgggtcta ccatacttgc tcataagctg
     9121 ttcactcact acctcacaat aaccagaatc acacaatcta agtataatcc tgtccatagt
     9181 tctaatactt acaccacata tagtagctaa ttcctttgat gtaaattcag tttttccact
     9241 atttattatt ttattgaata ctttatatac agtattagca cttagccctg tctctgtagc
     9301 aatttgataa aaacgttcat caaaactatt tttctctttg acagtaggat ttggctttag
     9361 tggtcccata atttctccat tttcaaaaac tacatatgct gcatcatttt tttgactttg
     9421 agccatctta atactctcat aagcgttaaa tttagcttca tttgctgttt ttccataacc
     9481 aattcctata taagtgttta taactgaaac ttcacgaatc atatccaaca aataaatatc
     9541 tctgtatttc tttgtttcta actcaagtat ttttttagtt gtaaaaatca taaattcact
     9601 tctactctgc tctaccaaaa caccatctat acggctattg aaatggtata gtttatcaag
     9661 aatcttaatc ctttgtgaaa gataagcgta ctcatcttcc ttcattagtg aatattctga
     9721 aggcatgttc agtttaatag caagaacaat aatctgattc tcattgtttt tctttgcaat
     9781 ataacgcatc tgaatgtttt ttatactttg caccattacg tcctcagaag gcaaggctaa
     9841 aactactgga atattatctt ttttcattat atgataggcc tcttcaagac ctgtaataca
     9901 acaacataca tcattatttt gataattata tttatgaaat tcaagcacaa actttatata
     9961 gtcctcttct aaatactttt gctctgcaaa aaacatatgt tcatccttaa attcaactcc
    10021 aatttcttta tacaatctct tcatcatagc cttatcataa gtatctatac taagtctact
    10081 aatatcgaat ttaagcaaat atgtaatttc aagcaacact ctgtacaatg ttgtttcatg
    10141 tctaggaata taatcagaca atacaaaatc tttttgtctt ttttcaaaaa atttaaatgg
    10201 cgacttacct gtaaaaagaa ctgcatccac tctacctcta tatttttcca ataaatcagg
    10261 tacttcaata tatctatcat atctaagaaa atctgcttca atattaggaa aattcttttt
    10321 acttactgct agtattttat cgattaccat acctggtcct acataaagta ttttcatttc
    10381 gtctctcctt tcctaatgat actattatct cttaaaacat tttctaaacc taccatgact
    10441 aaagccacag gactcctgat tcatagaatt ttgaataatc aattatacct aatataaaaa
    10501 gttactttaa gttttttaat tacgactatc tgttgaaaca tttttgtatt taaatttttg
    10561 tatttaaatc ttattcatta atattaatta cattttacaa ttaatatatt gttttttcta
    10621 cttaaagtta aattctttag aaaacacaag tagagtaatc tttattaatt taacaaaaat
    10681 agccttcctt aatattcaaa gaaagactat ttttataaaa gttcttaatg tattctattt
    10741 tgctatgcta agaggatttt taattacacg tccagcacat acatcagttt gctttcctcc
    10801 tgccaatgca attttaccat tcaccaacac atattccact cccactgtat actgtttagg
    10861 attactataa gtcgctttat cttctattgt atctgggtca aataccacaa tgtcagcaaa
    10921 ataattttct ttaagtagac ccctttcttt ataaatgcct aagcgttttg ctgaaagata
    10981 agttatcttt ttaactgctt cctcaaaagt caacatacct ttttctctaa catagtaaga
    11041 gaaaattcgt ccaaaagtac caaatgcacg aggatgaggc tttccaagag aaagtaaacc
    11101 ttctgtagaa aggtccatac tatcagaacc tatacatgac tttggatggc aaacaacctt
    11161 atctgtatcc tcttgacctt gtgtatgaac aactacttga attttacttt tttcttcaat
    11221 caaaagccta aagaacgtat caaatggatt ttcaccattg attttggcta cctccattaa
    11281 agttttaccc tctacatatt tatttgcttc agtcattaca gaggctagta caacaccgtt
    11341 ccacccacct gctaattggt agaaacattg ccatccagga atcccttcct ccaactcttt
    11401 tataattctg tctctatttt cttgtacttc taatcgtttt accatatttt ctacaccgcc
    11461 ttcaaaagcc caaggaggta aaagtgcacc caaagatgtc attccagctg tatatgggta
    11521 acaatcaaaa gttacttcca aaccatctgc ctcagcttca tctagctttt taaatacctc
    11581 atcaatagtt ccaaaattct tatgacccat aacttttaaa tgagaaatat gtagaggaac
    11641 tcctgcagtc ttagctatat aaattgcttc atcaagagct tccatttctt catcaccttc
    11701 atctctaata tgagatatat agtatccatt gtatggtatc aattccttac ataattcagc
    11761 catttcttct ttctttgtgt atgctcctgg taaataaact aatcctgatg aaagagctac
    11821 acatccagct tccatagctt ttctaacttc caacttcata tttttaagtt gctctaaagt
    11881 agctggttcc tttgaaaatc ccatttcatt gatacgtaca ggtccttgtg ctacataagc
    11941 tacaacattg actgctggag aattttcagt taagtaatca aagtattctt gcattgtatt
    12001 ccaatgaagc tctaattttg ttggaattgt accaattatc ctagttccaa gataatcaat
    12061 taactcttgc ttcttctctt ctcttatcgg agcaactcct ataccacagt ttgcaataac
    12121 atctgttgtt acacctgtat ggatacggct tcttgtgtat ttatcataca caagagataa
    12181 atcagaatga gtatggaaat ctataaaacc aggtgataca aattttccag ttgcgtctat
    12241 agtctcttta gcctcttttt gacttaaatc tccaatagcc atgattttgt ctcctacaat
    12301 ccctacatca cttttatatc ttgaatttcc tgtaccatca acgattattc cattgacaat
    12361 tttaacatca aacatgcttt ttctcctttc aagacttatt tatattcata tttcttaata
    12421 aacaatccta ttcttttttc tcaacaaata attctagtct ttctccttaa taaacaatcc
    12481 tattcttttt ctcaacaaat aattctagtc tttctcctta ataagcaatc ctattctttt
    12541 gttttattgt tatcaattac aaagaagacc cttgtgataa gtatcccacc taacacaata
    12601 aacaatgtta ataatccacc tggtatacca attttttcac caaagtacat aattgctaac
    12661 gctacagcaa tcgtacatcc accagctcga atatccttac gtgcaatatc aacataaatt
    12721 gctccaaata atgctggaag tatataatta aatgaattag taacaaattc aggtaacaaa
    12781 ggaattactt tatagcctac aatggtaaaa atggtaatca tagaagctga tacaaagatt
    12841 gaacaacatg taccaattgt tccaacaact tcaccctcat gagttcctgc ttctacacct
    12901 gcaattttct gtgccattga tgctgcaggc atacgtatat ctccaacaga acctgcaagc
    12961 caacctatat aagaacctgg agctcctagt gtaggataat aagctatagg ttgaacaatc
    13021 caactaaccc cataagtcgc agcgactaac ccccaaattt gaaatataac agaaagcatt
    13081 ggcatctgac caaagcgaat acctacatag atagcgggaa taaagtttgc aataattgca
    13141 agacctatag aaattctccc tatttttatc atctttttat catacataat tatcacctct
    13201 tatccgtttt aatcacgata atataatctg tgtaccaaac ataccaatta acatggcaat
    13261 acctaaggat aattcttgta atcgttgatt ctttttaaat aaagttgtca atactagcat
    13321 aactatagct gaaataattg ctggtgtaag ttttggtatt tcaaatgttt ttatttgatt
    13381 tgaaagaagg taagcaaata atccaactgt agcacctgca agtagttttt taacccaagt
    13441 aggattatac ttcatgttca tcttttcaac aattccacgc attctatgac ccaaaataaa
    13501 tacaacaaat agccaaccta agttatttaa agccatcccc catagtgcat acgaaaaagc
    13561 ttctgctcca aatgcagcac tacctacttc taccccagat aaattggatg taagagatat
    13621 tactccaagc tctgttctag ctgctccgac atcacagagc ctcatccaag tcgtaggagc
    13681 gccaatcaca gctaccagtg ataataatgt aataacagga gatagagaag gtccaatggc
    13741 tgtaacacta gctgagcgaa ttgctgcttt aattcctttc ttttcaatac caagatttga
    13801 agcctctttt agtgcctctt tcataaatac gattgcttga acaactgaaa taattactaa
    13861 aaaactagaa acaatccaaa gacctgggct attaatcatt tcttgaaact tcatacttta
    13921 ttcctcctta aaataaattt ttcagcattt tattgtgagc tttctttctg taatcttgtt
    13981 atgtttttat attgttttaa tttattttat ctaagatata gtatctttaa taggagatta
    14041 tctgtcttaa agtctcacta aaaacattaa tacttaaata ttttattcat aattagtaaa
    14101 tatcagaaaa ttcacatatt atttttttaa cctgtaatta acttataagg tcttttatta
    14161 ttttgacatt tcaatataaa aattttaatc aaaaaacttt attattttaa aaaaaattat
    14221 tatttttata atttatattt tttaagttta tttatgttca tctctatcta aaataatgac
    14281 atttctaact cttaattctc atttaagttt cattgttttt tcttaaaagc ctacttttag
    14341 tcaagatact gttatcttta ctcattattt aaagaactta ttttaaatct gtacatgaag
    14401 taaataatcc aaaagcattg ttattctaac tactcaacat taaatactta ctattttcta
    14461 attactcaat ataaagactt actataaaac taaatacata aatggcttct aaagtttaat
    14521 atatctacat ggctttatat atgacaggaa aaatactaga aaaaatatat tatagaatac
    14581 ttgtatataa taggcaaaac tttcaaactt aaatttatca aataatcata aaaaaagtga
    14641 accatctata gtaaaatttt atctaataag tgaaaggcaa aaaagtagcg ctacgatttg
    14701 catagaaggg aaggaactta gttggataaa actacattta caaacaatat acttgaatca
    14761 gaacagactt tgtatcgagt atctaagtct attctaggaa atgaccaaga ctgtgaagat
    14821 gccgtcaaca atgctatttt aaaagcatat gaaaagttgg attctcttaa ggaagaacaa
    14881 tactttaaaa catggctgat tagaatagtc ataaatgaat gtaattcatt aagacgcaaa
    14941 cgattaaaat ctctatcatt tgaagatgtc ttcaaaaaca aaaaaattga tgaaaaagat
    15001 gactatagcg atttgtatac tgctattcaa agtctaccta aaaaaattaa aattccaata
    15061 gtcctttact atattgaagg ttattcagta gatgaagtta aggaaatatt agatatacct
    15121 caaggaactg taaaaagtag attatcaaga ggaagaagat tattaaaaac taaattagaa
    15181 aacacagagg taatcatatg aataaaaata tattaaataa ttcgtttcca gaagttccag
    15241 aaagttttca taatagttta agcaaaacac taaatagttt accagaaaga gaggaaaatt
    15301 ataaaatgat taataataaa acacacaaat taccatttag aaaaggctta gttgcaactt
    15361 tagccattac tttgatattg agcacaacag cccttgcagt aggacatata tatagtttag
    15421 ttggaaaatc aagtactaag gctacctata catctatccc aactacagaa caagtaaaaa
    15481 aagactttaa ctttacccct aatatagttt ctgaatttag taatggatat aaatttaaag
    15541 gagcatatac tgtaaataaa aaagcatttg acaaagaaaa taatgtttta ggaaaatcaa
    15601 aagcacttag ttttgaatat aaaaatggca atgatgaaat atctcttgac acagcaaata
    15661 atgtacttgg gaagagttct gacaatctaa aagttgtaga tacttacaaa gatattaata
    15721 tttcttatga agcattcgca caaaagttta taccagaagg ttataaaatg acagaacagg
    15781 ataaaattga tgaaaaatca ggcaaataca catttagtgt ggggccaaat aatgaatcag
    15841 acaaagttga agttaatgaa tttaagtttt tgacatggaa acaagatgga gtttactatt
    15901 cttttacagt tcaagactca aatttatcta tgaatgactt agttaaaatg gctcatgaag
    15961 taatagatgc aaaataaaca taagtaataa taagttgttt atgagtttat tatttatgac
    16021 tttaattttt ttattagtaa acatggttgt atcttccatc tttatatttt ctttaaattt
    16081 aatatataaa attttagata tttagctacc ttcaaaagaa gcattattaa aaagccctta
    16141 aaaatatttc ttttatatgg aattttaagg gctttaactt tattttatac aagtgtatat
    16201 ggaattttaa agactttaac tttattttat ataagtgtaa gctccatttg aattacttct
    16261 tcttttacag gtctatcatt ccatgtaaaa ccactagata ttgtatttac ctctacaaac
    16321 cctaaagatt tataaacatg aatagctcta ctattacttt taaatacatc aagctcaatt
    16381 ttttcatacc catattcttt tgataaatca ataatttgtt ttaaaagact acttccgata
    16441 cctttttccc tatactcttt aagaataccc atgcctaaat aaccaacttt ttcagtttta
    16501 ggtaaaacgt cacaccaacc aatacagtta tctgattcta aatcaattat aaacagttgt
    16561 ggtaagtttt tatttataat attttttata aattcaactg tttcttcaaa aggaaaggct
    16621 tcatccatag ctagatattt cctctctttt gctattttat caaaagtttg ccaatacgaa
    16681 taaatatact tttcttctgc ctttataaat tttatgcctt ctatcaactt aacatttccc
    16741 ctttttaatt tttgattgta gttaacttat tttatatgat tctagtttat aatgctatat
    16801 aaattactat atattagctt aaaatatctt tgtatatttc tataaaatta aaaccaatat
    16861 atctatctct tgcatctcta ttaaaataat ttttaatagt ataataaata tagttcttta
    16921 atcttttggg tatatatact taatcatttt gaaatttgat ttaaagtata ataaaatata
    16981 taaaaaaata tataaaatgg tactataaaa tttttaatct tcatcaatac cttttttgct
    17041 ttcattgtta aaactatttt ttctattagt ttatttctta taaaacaaac atttagtatt
    17101 aaaatatata tcacacaata gtatttgcaa tttaacttta aaaaaataaa aatacccaac
    17161 tgacctaagc aactcgattg ggtataaata atctaaaaaa tcatttttgt ataaactctt
    17221 tatttaactt acatttttat ttaccttcta ctttaattca acttatattt ctatgcttct
    17281 tatactctca ttcaacttat atttctactt atcttatact tttataaatt catcacaatt
    17341 atttagttct cgctatcaaa gaaattgtat taaaatactt tccattctct acttccatca
    17401 tttttttgtc atttatagca tatgaattat cacaatttat ccaatccttc caagcttcat
    17461 catgacaatt taaagcttca catttctcta caatcacaga ctccgattca gaccaaagtt
    17521 tattccacca tgtaattgaa tggaagttca tattatcttg ccaaaatgga atgagttcat
    17581 ctggtataca atccacgaaa tcttctttta atccaggcat tgccatagca agtattcccc
    17641 cctcttttac aagaggtgat atatgattgt ctaaaaatcc ttctttgttt ccaaaatagt
    17701 gataagaatc gatacttatc accgcatcaa agaaaccttc tgcataaggt agttcatgtg
    17761 cctctgcctg tattggaaat attttatcat ccaatttaaa ctctttaaat cttttatagt
    17821 tttcagttgg ttctatccat aaatctgttg caaatacagt agcatcaaat tcctttgcta
    17881 aaaatatcga agatataccc ttaccacaac ctaagtctaa aatacgcatt cccttttcta
    17941 gttttatctt acttgttaat tcttccaata tttttataca attaggtccc atcatatttt
    18001 tcatgagaaa gtccttatcg tatttattac tttttgtaaa tatcattcta tctttccttt
    18061 ccctatcagt tattatttat taaattttat acgtttgatt ttttattttt tatctgcttc
    18121 ttatattgag caatctcttt tttattcatt ctttaacaga caattttaat gtgtaatttt
    18181 atccactctg tgatagtaac tttaatgaat aatcttatct actgtgatag ttattttagt
    18241 gagtaatttt atctactcca cagcaatcgc tttaatgagt aatcttatcc actctatgat
    18301 agttatttta gtgagtaatt ttatctactc cacagtaatc gctttaacga gtaatcttat
    18361 ctactctata atagtcactt taatgagtaa tcataatttt tatatcattt tagatactta
    18421 ctctaataag aattcatttt ctaatactta ataagtttta attacttcca ctttaaccta
    18481 tatactaatt aacttattta atttagtgca tatttgacac tttacctttt attataccat
    18541 ttattatcat aaatataata attctatttt tttaaaataa atatttataa taatctaaaa
    18601 taaatattta taaattctaa tcaaccgtaa ataataatct aaaatacatc aaaaaataaa
    18661 ctaaaaaata tcgaaaaata atttaaaaga catcaaaact aaatcttcta atcagcaatt
    18721 aaaagtctat tttcttagtt taaaaaataa agatagattt tttcaaaaca ctggataaat
    18781 aggtaaaaaa ataaacagtt agtaaaataa atttttacta actgtttatt tttattgttt
    18841 aatatgtcct ataaatcctc taagtaatat tttccttgca aaaattctga ttctaaacct
    18901 agatttttaa aataatcaac catgcccata cacgcaaatt tttctgtaga ataatgagta
    18961 gcacctataa cattaattaa attatctttt gctatttgat ggaactctaa tactggttca
    19021 aaatgtttta aaggcttagt aaacccagta atatatagat ttataccaag ttcagcaact
    19081 tctcttgcta caaatggata acttcctccc cctgctgcaa tagcaactaa accatctttt
    19141 aatacagaat ctccataatc atacaatttc acatcatgac caacagattt tttaattaat
    19201 tccttaatct cttctattga ttttagtgat gttttacata taactcctac ctcaatttta
    19261 tcgtcatatt tacaaaatgg tttgactatt tctaaaccca tagcttttgc aaaactaaca
    19321 gaagttgaat agtcactata gttgtctagt ggagaatgta atacataaaa agaaattcta
    19381 cgatttttca tctcttccat ataagatagt ggtatgtcgt gaaatggaaa accttcatct
    19441 gatgctatgt atcccattgc atgatgtgaa aaaattaaaa tatctttttc atctttatct
    19501 ataacttgct taattatttc tttatcagga aaagtagttg tgtatacttt attaatattt
    19561 tgagcattat ctaatactaa tcctatgtat ttttttctaa attctggagt aataaaatca
    19621 ttttcaaaat tcataaaact ccaatcatca ttaatatttt taatattaaa ttctaaatct
    19681 aattttttat aaagttcaat tgccttaata ataaccactc ctttataata atattgaatt
    19741 actacatatt aatatagaaa tttccgata
//
LOCUS       DAMJWC010000067        19752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMJWC010000067 DAMJWC010000000
VERSION     DAMJWC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.067"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            38..994
                     /locus_tag="PC503_002900"
     CDS             38..994
                     /locus_tag="PC503_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2528866.1"
                     /translation="MISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDE
                     LEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGG
                     GLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLN
                     TSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNKQGHG
                     VEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSND
                     MPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            1236..3149
                     /locus_tag="PC503_002901"
     CDS             1236..3149
                     /locus_tag="PC503_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528867.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERSLRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            3142..5361
                     /locus_tag="PC503_002902"
     CDS             3142..5361
                     /locus_tag="PC503_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2528868.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            5470..6300
                     /locus_tag="PC503_002903"
     CDS             5470..6300
                     /locus_tag="PC503_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF2528869.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            6290..9757
                     /gene="addB"
                     /locus_tag="PC503_002904"
     CDS             6290..9757
                     /gene="addB"
                     /locus_tag="PC503_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF2528870.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            9757..13584
                     /gene="addA"
                     /locus_tag="PC503_002905"
     CDS             9757..13584
                     /gene="addA"
                     /locus_tag="PC503_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF2528871.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGCRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVNNPDSDY
                     YGEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            13630..14841
                     /locus_tag="PC503_002906"
     CDS             13630..14841
                     /locus_tag="PC503_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF2528872.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            14828..18355
                     /locus_tag="PC503_002907"
     CDS             14828..18355
                     /locus_tag="PC503_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2528873.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKDNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            18486..19739
                     /locus_tag="PC503_002908"
     CDS             18486..19739
                     /locus_tag="PC503_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2528874.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
BASE COUNT         8565 a         1830 c         3520 g         5837 t
ORIGIN      
        1 ggatttacaa aatgcttatt ttataggtgg tcctcaaatg atatcaacaa atgttataaa
       61 taaggtaaat ggaataacta aagatagtgt tactaataat agagtatacg gagcagatag
      121 acacgaaaca aatgcaaacg taataaaaaa attctataca gatgatgagt tagaggctgt
      181 tttagtagct aaatcagatg tacttgttga tgctttagca gcaggtccat tggctgcgaa
      241 cctaaagtct ccaatactta taacaccaaa gacgtatgta tctgcatacc ataaagataa
      301 tttagaagct aaatcagcta ataaggtata caaaatagga ggaggattga cttctaaggt
      361 aatgagctct atagcatcat cattatctaa acacaatacg actccaacag aaccaggaaa
      421 tagtgggggc aagacagtta tgattgaccc agggcatggt ggttcagcac ctggaaattc
      481 atctggagga atgattgaaa aagattacaa tttaaatact tcacttgcaa caactgaata
      541 tttacgttca aagggattca atgtaataat gacaagagac acagataaga ctttatctct
      601 tggaaataga actgctctat ctaattcatt gaaaccagat ttatttacaa gtatacatta
      661 taatggctca actaataaac aaggtcatgg tgtagaagta ttttataagc ttaaagataa
      721 aaatggaggg actactaaaa ctgtagctac caatatatta aatagaattt tagagaaatt
      781 taaacttaca aatagaggta taaaaacaag agtacttcct agtgattcta caaaagatta
      841 tttatacgtt ttaagaagta atgatatgcc agctgtactt gtagaatgtg catttttgga
      901 taatgaaaat gatatgagtt taataaactc atctgcaaaa gtaaaagaaa tgggtacaca
      961 aataggtaaa ggaatagaag attcattaaa ataaatggaa ataaaaatat ttaaaaactt
     1021 aatgtaaatt tatagttgta aatttatact aaagtcaaaa aatgaaatat aagtgtatca
     1081 atagtaagac tgtatgtaca tttgcacgtg tgaatgcaag tatatataca gtcttttttt
     1141 gtagttaaat gcaataattt gaatgtgttt tgtaaaatac acaatatgat ataattagat
     1201 aatatacact taatttaatt gaggaaggtg attatatgga atatttattt gaaaaaagta
     1261 gtttaaaaga atatggaaat gaagctttag ataaatatag agaattatta gataaaactg
     1321 gtaataattc aaggtgtatt cttttgttag taccaaacaa taacacaaag atacgatatg
     1381 aaaggtctct aagattaaat tatagtgaag aactgaaaat aacaacatat ataagttttg
     1441 tgaagaaaga attagttaaa tactggccac taataataga aaaatgtgat gaaataagta
     1501 caaaggttgt atctccaaca tttatatcaa atagtttaag tgaatattta atagtgcaaa
     1561 aagttaagga aaaaaggata caagaaggat attttgaaga tattacagga accaataaat
     1621 ccatagcaaa tagtataatg actaacataa ataagtctgc atttaattta attgattttg
     1681 attttattgg agaaaaaata tattcatcaa agaaaaataa agatagtata tatagatttt
     1741 catacactca aatggatgaa attatatcat attatataaa ttccttacta tcaaattcaa
     1801 ttttagataa tgcattaagc atatatttat acaatcaata cctacttaat gatgattttt
     1861 atttaaaaaa cttatttaca gaagtgagat atataattgt ggatagcctt gaaagctcaa
     1921 gtaatgcaga agttgatttt ataacagaag cattggataa tacattacaa agttatatat
     1981 attttgatta tagtagggat tattctgtat ttaataatgt ggatatagac tatataaatg
     2041 agaaaataat atcaaaaatt aagcctaaag aagaaaatat taaaaagaag gagattagaa
     2101 tagaagattt atacttatta cctgcaaata tagaattaaa tcaatcaagt caattatata
     2161 atgaaatgtt agatttaata agtgaaaaag ttatatctct tatagaagaa gatgtatctc
     2221 caagagatat agcaattata tctcctataa acaatagtat attggagcat caaattagag
     2281 attctttgat agaaaaaaat atagatgttt ttagtactaa gaaggataaa aaagctgtgg
     2341 attatccata tgggaatgca ttggtagtgg ctacatgtat attttatgga tatttagatt
     2401 ttataaaaga tgatgaatac ttaagctttt tagaaactct tttagaaata aataggataa
     2461 aagcatttaa gatttttaat gaaacaagac atttaagtat tgataatata gatgaacata
     2521 gtcagtatcg tgagatttta cagtatattg aagaaaaaaa gaagagtgat ataaaaatac
     2581 atgaattttt aactcaattt tacatagata aaatgttaaa tttaaaagaa ggtaaaaaga
     2641 atgttgggtt atgtaaaaag ataatagctg aaagtgagtc ttttagtgaa agtttaagtc
     2701 tacttgggat gaaaaaagaa aagatattta tagaagcttt aaaaagtaca ataaacgatt
     2761 attactctgt tgtcgatata gaagagttga aatccaaaga caaaatagta ataactactc
     2821 cttattcata tatatcatca aatatagata gaagtataca aatatgggta gatataggaa
     2881 gtaatgcttg gaatatgaaa atagaaaaag atataagtaa tttaattgta cttagaaaat
     2941 cttttgaaga aaaaaagatt tatacaaatg aaatggaaga atattataaa aaatactatc
     3001 tatacaatac agtatataat ttgttattaa atgcaaagaa aatctatgca tttaaaagtg
     3061 aatatgcgat taatggttat atccaagaga gtatattata tagtatactt ttaaaaatct
     3121 cacataaagg agataaaaat tatgattaat ataaattata gagaagacca gataccaata
     3181 ataaattacg ataatggtac tatggcagta ccagcagtac caggtgctgg aaaaacattt
     3241 ataataacaa atttagtagc taaactatta cttgagcaga aacataaggg tggtaaaata
     3301 ttaattctta catatatgaa tagtgctgta aataatttta aaggtagaat aagaaaaatt
     3361 cttgaagaga ataaaataga tgatactaat tcgtatgaag taatgactat acacagtttg
     3421 gctgtaaaaa taataaagga aaagccagaa gttgtaatgt taagtgagga ttttaacata
     3481 gctgacgatt tgcaaaaaag tattatatta aatgaatgta taagtagatt tagatttgaa
     3541 ggtggagaaa gagcttttag atggttttta aaggagcaaa aagatgaacg ctggaaagaa
     3601 ataactcttg aagcctggga aagaggtttt tttgaatttg caggaaatgc aataagtgaa
     3661 cttaagtata agggaatttc tccagataac cttgaagaaa tattgtcaag aggacacaaa
     3721 ggaatgctta aaattatttt accaatatat aaattgtatg atagaaaatt aaagcaaaat
     3781 ggattgctag attatgatga tatattaatt ttagcagaaa aaactttaag cttagacgaa
     3841 gggcttagaa agaagtttca aactagatac aaatatatat ttgaagatga gtgtcaggac
     3901 tcaaatgaaa ttcaaggtaa tataataaaa attatatcta gcgaaaataa aaacctagtt
     3961 agagttggag atataaatca gagtataaca ggaacatttt catcatcaga ccctaaattt
     4021 tttaaagaat ttataaatag tgcagatttc tgttatagga tggatatgtc aaatcgaagt
     4081 tcaaaagata tacttgattt agcaaacact cttgtcaagt atgttacaaa ggaatttaga
     4141 cagaaagaat gtagacatgc tcttgaagat atgcaaataa aaactgtgcc aaatggaatg
     4201 ggatataaag aaaatcctaa tccagaacat tataatataa atgtaaagtg gtatgagagt
     4261 tggaaaattg aaatagagca aactgctaga tatgttaaag gtataaaaaa taaatatcca
     4321 gataaaagta taggtatatt ggttccattt aatgaacaag tgacacaagt tgctaaagaa
     4381 cttagagaga ataatctaac ttttgaagaa ttaggaccaa attctttgaa taaaaggaag
     4441 gttataaaca acatagcata tattattgat tttatgttac attgtgatga tgtagaaaag
     4501 ttaatagttg tacttaataa agtttttata gatactgata atgaagaaga aataaagtat
     4561 tttttagaag aattaaaaaa ctattctact gaagaaatta tttataattt tgaatttagt
     4621 aagttagata atgatttaat agaatttaaa gaagaaagtg acatatattt aagttttaaa
     4681 agaggaatag atattataaa acagatatta gaatatccaa taataaggtt agacctctta
     4741 gttttgttta ttgggaaaaa acttaattta gaaaaagaag ataaagctgt actggattat
     4801 atatcttttt atataaagta tctagtatca gaaaatataa atatggattt agaagatgta
     4861 tataatttat tgtttgatgt aaagaacagg gtgtttaatc atataataga tgtggtatat
     4921 gagataaatg gatatgaacc agagcccggt agtataacac tatgtaacta tcataaatca
     4981 aaggggatgg aatgggattg tgtgttttta ctaggtcttg ttgaatataa tttccctgac
     5041 aatattaatc aaaagtttca gagtgataaa tggtatctaa aagaaaaata taaaaaccct
     5101 atggcaatta ttaaatcaga agttgaagct atattaaaag gaagtatttc aacagattat
     5161 gctcataaaa cgaagattga ttctataaat gaaaagatta gacttttata tgtagggatt
     5221 actagagcaa aggaaatgtt agtactttca ggaagtgctt atagagatga aagtgatata
     5281 gggaataaga gaaaagagca aaaaccatgt atatatttaa gcagacttaa tcaacatatt
     5341 attgaaaaaa ggtcaaatta atatataata agttattaaa agattgcttg aaatatatct
     5401 aaaaggggat aaaacaatat gtacagtaag taactactaa aaaataaagt taagagagaa
     5461 gtgatatgag tgaacgataa attaaaatat ttttcttata gtcaaaattc aattaacaca
     5521 tataaatcat gtccattgaa atttaaatat aaatatattg atagaataaa ttggaaaaat
     5581 gatgatgttg gtagtagaga gtattatgaa actttaaaaa caggaagaga ttttcatttg
     5641 atttgtgaaa gatattttag caatatacct cttggaatct attttaatga ggatgataaa
     5701 aatagtaaaa agtttttaaa gtggatggaa aatataaaaa aagttgttcc tattgaaaaa
     5761 ggaaaaacgt atttgccaga atatgaagta aggatgacat taaatgggga tataatacag
     5821 gcaaagtatg atttagttgt aattggaaat aacaatatag aaatatggga ttggaaaacc
     5881 gagtctaaaa agattgacta taaacacgta gaaaatagaa tacaaactat tgtttatatg
     5941 tttttagcaa aagaagtaat acctaaagtt ttaaaaatgg acataaatgt taaagatata
     6001 aatatgagat attatcaacc tgaatttgat gacttaccaa ttaccatttt atatgatgaa
     6061 gaaaaacatg aagcaaatag aaataaaatt caaaattata taagtatgat aaaaaacact
     6121 aattatgaag aacatacata cgaagacaat ctatacaatg atatagaaaa ggtatataat
     6181 aaagaagaac gtatgtgcta tagaaataaa aagcattgca agtattgtga atttaataag
     6241 ttatgtaatg gcaaagaaat agattatagt attttggagg cggaaattta tgggacttag
     6301 gtttgtatta ggtagaagtg gaagtggaaa atccacctat atactagatg aaattaaaaa
     6361 agaagctcaa aaaaatgaaa cgacatcaat tatactttta gttccagaac agtacacatt
     6421 tgaggctgaa aatagagtaa gtaaactatt tttaggaaaa gaaaaagata agtatctaag
     6481 agttagggta cttagcttta agacactaag taatatagtt ttttctcaag taggaggatt
     6541 gacagatgta aatataaatt ctagtggaaa agcaatgatg gtatatagag ctattgaaga
     6601 tgtaagtgaa gaattaaatg tgttttcaaa atcaaaatcg cagtctggtt ttgtaagttc
     6661 aattacagat atgatatcag aaatgaaaca atacaatata agccctgaaa tgttagaaaa
     6721 tatatctgga gaattggata atgaaacttt aagtttaaaa ttaaaagata taagtaaaat
     6781 atataattct tttgaaggga aattgcatga aaattatgta gatgctcaag atatgttaac
     6841 ttcattggca agtaaaattg aattaagcag ttatttagat ggagcttgtg tttatataga
     6901 tgaatttaca ggttttacac caaatcagta caatgtcata aagagtatat taaataagtc
     6961 taaaagtgtt aatatctctt tgactgtaga tgatatcaac tatattgggt acagtaaatc
     7021 tgatatgttt tctagaacga aatttactta ttcaaaattg actcaattgt gcaacgaaga
     7081 aggcataaaa atattgccac aagtaaattt aaacacaggt gttataaaaa gatttgaaaa
     7141 agttaaggaa ttacagcact tagaaagatt ttataatgct tatccatata aaatatattc
     7201 aaatccaact gaaaatataa agataaaaga gtttaacaat ttatattcag aggtggaaga
     7261 gatagccaga gaaattgtac atttagttag agataagaat gtcagatata gagatataac
     7321 cattgctaca agagatttaa atagatatga ttttttagta cactctatat ttaatgaata
     7381 taatatacca aactttatag ataagaagag agaggcaaaa agtaatccaa tagttatttt
     7441 aattatttca gctttagaaa tgaagaatag acgatatggg tatgaaacta tgtttaggta
     7501 tttaaaaagt ggacttatag gaattgataa tgatgatata aatttactag aaaattatgt
     7561 gttggctaat gggattaaag gtaaaaaatg gtttgatgaa aaatgggatt atagaataac
     7621 ccaaagtctt tcaggtcaag aaagtgaatt tgaactggaa ttaaaagaga aaataaatga
     7681 aataaaaaat agagtattag agcctatagt aattttacaa gaaaaattaa gaggaaaaaa
     7741 tagagtaaaa gaaatctgta gatatatata tgaattttta ttagatataa atatgccaga
     7801 aactatagaa agtttaatag taaattttaa ggataaaggg gaacttgatg ttgcaaatca
     7861 atactcacaa gtttgggaca tagtagtgga catattagac caaatggtgg aacttatggg
     7921 tgatgaaata atttctttag aaaaatttat aaaattaata accttaggtt ttgatgaata
     7981 tgaattagga ctggttcctc ctagtataga ccaggtactt gtaagtagtg tggatagaat
     8041 gaaaaatcca gacacgaaat atttatacct agttggaact actgatggtg tgtttccgct
     8101 gattacaaag gatagtggaa tattgagtga taatgatagg gaaagtcttg gaaacaaagg
     8161 aatcgaagtt gatattgata gtaagactag gagttttgaa gaacagtttc ttgtatataa
     8221 agctcttact tcgacatcta agaatttaac cataacatat ccaatatcag accatgaagg
     8281 taaaacgctt agaccatcaa taattatatc aagacttaag aagatatttc caaatataga
     8341 aaataaaagt tatttagtgg aagaaaataa aagcactgat aaagatatac ttaaaaaaat
     8401 aacggttaaa tcccctacat ttaatgaact tataaacgta ataaaaaatt atgacagtga
     8461 tggttacaat acagaagaga ttaatagtat ttggttagat atatataggt actatttaaa
     8521 agatgaaatc tatagttcta taacaaaaaa agttataaaa ggtcttagtt atactaatca
     8581 agttcataag attgaagaga aaaaaataag gtcattgtat aaaagtaatt ctcttagcat
     8641 atctaggctt gaaaaatatg ctgaatgtcc atttgcttac tttatacaat atggtctaaa
     8701 agcaaaaaag cgtaaagagt attcatttac accaccagat ttaggaactt ttattcataa
     8761 tattttagat aggttttcaa aagaactttt acaagataat ttaacttgga gagatattga
     8821 tgaaaaatat atagaattaa agataggtat aatagttgat gaaataattt taaagatacc
     8881 aggatatata ttaaatagtt ctgagaggta taaatacctt gcatatagat taaagaatat
     8941 gttgacaact gctataacta taattagtca gcaaataaaa caaggttcat ttgaaccaat
     9001 agattatgaa gttaaatttg gcaacaatgg aaaatatcca cctataaaaa tggtgttaga
     9061 aaatggacaa gaagtaagtt taattggaca aatagataga gttgatgaat ttgaagaagg
     9121 agaaaataaa tatataagaa taatagatta taagtcaggc aataagtcca taagtctaac
     9181 agaaatatat tatggtctac aattacaatt acttgtgtat ttagatgcaa tccttgaaag
     9241 tgcaaaggat gaagatataa atataaatcc agctgcaata ctatattgta gaataaataa
     9301 tccaatagca aaatttaatg aagataaaga tgatgaagaa atacaagaag caatattaaa
     9361 agaacttaga atgaaggggc ttgtagtaaa agactctcac atagttaaag agatggataa
     9421 atcattaata gatggagaaa ggaaaaactc tttagtaata ccagtaggtc ttactaagga
     9481 tggaaatgta ggtaaaagta cttcagcaat aagctatgag gatttcaaac tgcttagaaa
     9541 atatgtaagg catgctataa aggatttatg tgaagaaatg ttaagtggag aaatacgtat
     9601 agctccatat aaacataaag atggaacatc atgtgacttt tgtgattact ctgctatatg
     9661 tcagtttgat tcaactataa aagataacaa gtataaaaat ttaaataata agagtaatga
     9721 agagataata aaaatgatga aaggagatgt taattagtga gttctcctaa atggacaaaa
     9781 gagcaattag aagttataga aagtagagaa tgcaatttat tggttgctgc tgctgctggt
     9841 tcaggaaaaa cagccgttct agttgagcgt ataattcaaa tgataacaag tagagaaaat
     9901 ccaattgata tagataagtt attagttgtt acatttacta atgctgctgc gtcagaaatg
     9961 agagagagga taggggatgc tataggaaaa gccttagatg aaaacccaga aaataaacat
    10021 ttacaaaacc aacttgtttt attaaataaa tctagtatta caacaataca ctcattctgt
    10081 ttggatgtta taaaatcaaa ctttcataga ataaacttag accctaattt cagaatagga
    10141 gaccaaactg aatgtgctat tttgaaacaa gaagcaatag aggaagtatt tgaagattta
    10201 tatgaagaaa gagatgaggg gtttttaaat ttagttgaaa gttatgcaga aagaggagga
    10261 gataaagaag tacaagatat tatcttggga atatattcat ttgcaatggc ttctcctgaa
    10321 cctaaaaaat ggttgattga ctcagcagaa cgatttaata ttgatgaaaa ttttgatttt
    10381 tcacagtcta tttgggctag agctatatta gacactgtaa aaatagagat taatggtctt
    10441 tgtctaaata tggaaagggc attaaaagaa gtggaatcaa tagaagaatt agaaactttt
    10501 gcagaaaagt tatccgttga atataaaaaa attgctgaca tttcacaagc atgtaataaa
    10561 tcttgggatg aggcatataa aaagatggca agtatgtcct ttgaaaatta tgtaaaagga
    10621 gtaaaaagaa tttcaaaaga tgctccttcg tatataaaag aatcaaaaga aaaggcaaaa
    10681 actataagag ataagactaa gaagtcttta gaaagtatag taagtgctac attcaataaa
    10741 gataatgatt ctattagaga agaaataaaa tatctttata acatagttaa accaatatct
    10801 agtgttgtac tgagatttga agaggaatat agcaataaga aaagagaaaa aggaataata
    10861 gattttaacg atatagagca ttttgcatta aatatactta cagatgtaga tgaaaaaggt
    10921 aatattgtac cttctgatat agcagttgga tgtagaaaca agttttatga aatatttata
    10981 gatgaatatc aggatagtaa tctagtgcag gaagtactgc ttaaagctgt tgcaaataca
    11041 gaaactccaa atagatttat ggttggtgat gtaaaacaga gtatatatag atttagacaa
    11101 gcaaagccag aattattttt gcaaaaatat aataactata atgataaaaa gggaagctcc
    11161 catagaaaaa taatgcttta caaaaacttt agaagtagag aagaagttgt agatgctgta
    11221 aattatatat ttgaaaatat aatgaatgag aatataggag aaattgaata tacagaaaaa
    11281 gaaagactaa atttaggtgc aaattttaat gtggatacag acgagaaatc tattattggt
    11341 ggagcaacgg agatacacct aatacaaaaa gataataaac ttgatgatga tattataaat
    11401 gataaagacg atagaattaa taacaaagaa aatgaaatag aggaagaaga aaaattagat
    11461 aatatacaac ttgaggctag aatggttgga aacattatca aagatttaat gaaagtcaat
    11521 gaagatggaa aaattcaaaa ggtctatgat aagggaatag atggatatag acctgtggaa
    11581 tttagagata tagttattct tttaagagct acatctgcat gggctccagt gtttgcagat
    11641 gaattgatga atatggatat accaacgtat gctgatgttg gagtggggta ttttgatacg
    11701 attgaaataa aaacaatatt gtcattactt caaataatag ataatccaat gcaagatata
    11761 cctcttatat ctgtattaaa atcacctata tttggattta caccagagga tttgattgat
    11821 attagagttc agagtaaaga taaaattttt tatgaggttt taaaaagtac agcagagtat
    11881 gatggattta cagattctca aaatgaaaat gagtctgagt ttataccaag tgaagagtgc
    11941 ataaacaaaa gtaaagattt tttaattaag ctaaaggaat ttaaagaaaa gtcaatgtac
    12001 atgagtacag atgaatttat atggtacttg tacacaagga ctggatacta tgcctatgtt
    12061 ggagcattgc caggtggaag tcaaagacaa gctaatttaa aagtattgtt tgagagagca
    12121 aaacaatttg aagaaaccag tcttaaagga atattcaact ttgtaaattt tatagagaaa
    12181 ttaaaaaaat ctagttctga tatgggaagt gcaaaaacac ttggtgagaa tgcaaatgtt
    12241 gttagaataa tgagtattca taaaagtaaa ggtctagaat ttccagtagt catatgctct
    12301 gcaatgggta aaaatttcaa tactcaagat tttaaaaaga gtattttata tcatcataat
    12361 ttagggtatg gacctcaatt tgtagactat gagagaagga tttcttttcc aagtatagcc
    12421 aaagaagcat taaaaagcaa aataaatata gaaaatttat cagaagagat gagagtttta
    12481 tatgttgcat ttacaagagc taaagaaaaa ttgattataa ctggttctac tagaaatata
    12541 caagatagta taaagagatg gtcaaatgga attgaaagtt tagatacaat atcacaatac
    12601 gagatattaa aaggtaaaaa ttttttagat tggataatgc cttgtgtatt aagacatagg
    12661 gatttatcta atctactaga agaagtagga ttagacgcag tttttaatgt tgaacataat
    12721 tcaaaatggt atggaaagtt gtggaataag aatgatattt tagtggaaaa gaagagtgat
    12781 gaagaaaaag aaagtattga agaaattctt gaaaaaatag atgtaaataa tcctgacagt
    12841 gattattacg gtgaaataga agaaaaatta aactatatat atccatatga atttagtaca
    12901 agaaaacctg ctactatatc tgttacagaa ataaaaaaga tacaaaataa ttatgaagaa
    12961 gagttaataa atactatatt tgaacaaaaa gtaatattaa aaaagcctct atttattcaa
    13021 aatgaagaag aaagagaaaa aataagtgga acagaaagag gtacaatagt ccatttagtt
    13081 atggaggttt tagacttaaa aaatgtaagt agtgtaaatg atataaaatc acaaataaga
    13141 ggttttgttt caaaaggtat aataacagaa aaacaagcta gtatagtaaa tccatataaa
    13201 atatataaat tttttgcctc taacatagga aaaagaatgt tgaatgctga aattataaat
    13261 agagaaaaat caatttatgc acaagtaaat atgaaagaca tatatattta tgaaaagctt
    13321 ataaacaatg acgataaaaa actttatgat aatgaaagtg tcatgttaag aggtatagtt
    13381 gatgcttatt ttgaagaaga taatcaaata gttttggtgg attataaaac agattttgta
    13441 aatgaggaaa atataaatca aataatagag aaatataaaa aacagttgga tttatatgca
    13501 gatattattg aaactttaac tggtaagtca gtaaaagaga aatgtatata tttatttgga
    13561 gttgatgaag ctgtttgtta ttagttttta tatataaatt aaacctaaaa gatagaggaa
    13621 ggggaaaaaa tgagatttat tcatacatca gattggcatc tagggaagtc cctagaaggc
    13681 cattctagaa ttgaggaaca agcaaagttt tgtgaggaat ttataaaaat agtagaatca
    13741 aatgaaatag atatggttat aattgctgga gatgtatatg atacttctaa tcccccagca
    13801 caagcagaaa aactatttta tcagactgta tcaagacttg ccaataatgg tcagaggtgt
    13861 gtattaataa tttcaggaaa tcatgataat ccagagagac tctctgcaat aacacctcta
    13921 gcacatgaac aggggatact tatatatggt tatccattaa gtgctacgat agaagctaag
    13981 tataaagggt ttgaaataac atatgcaact cagggatgta caaaactgaa tataaatgga
    14041 gaaaatattg tggttgctac attaccttat ccaagtgaaa aaagattaaa tgaagttttt
    14101 tcaagtgaag atgagtttga gaaacaaaaa aattattctg aaaaggtagg agatatattt
    14161 agaagtttag aagaaaattt tagaagtgat actataaata tagccgtatc acatatattt
    14221 gtaataggtg gagagagtac tgaatcagaa agacctatac agttaggtgg aagtttttta
    14281 gttgaaagaa aagatttgcc agaaaaggct caatatactg cactaggtca tttacataaa
    14341 caacaaaaag cttccgaacg tttaaatgca tactattctg gttctccact tcaatatagc
    14401 aaggatgaga gagcgtatac caaaggggca tacatagtgg atataaaagc tggtgaaaaa
    14461 ccaataattg aagatgtata ttttaataat tacaaaccta tagaagtatt taaatgtaat
    14521 ggaatagaag aagcactaga tatatgtgag caaaatcaag atagagagat ttggtcatat
    14581 tttgaaataa atactgatga gataatatca cagaatgaaa ttaaaaaaat gaaggaacta
    14641 ttaaaagaca taatagaaat aaaaccaata ataacatctt gttatgaaca agaaagtgta
    14701 gatataaaag aaaagtctat ggcagagttg tttagagagt tctattcttt tagtaaaggt
    14761 gtagagccaa aaggagaact tatggattta tttctagata taataagtga agaaggtgaa
    14821 tcagcagatg agaccaatta gattagaact tacagggctt aatagctata ttgataaaca
    14881 agttatagac tttgaaaaat taattgaaag aggtttgttt gggatatttg gaactactgg
    14941 aagtggaaaa tctacaatct tagatgcaat aactattgct atgtatggaa atatatccag
    15001 aaatacaaaa gaatatataa acagtgtgtg cgataaggca attatatcat acgagtttga
    15061 gataggaagc aaaaacacta gaagaagata cattgtagat agaaccattg ctagaagcaa
    15121 aacaggaaca aagacctcta atgctagatt aatagaagta ttgaatgaca atacccaaaa
    15181 tgttttagct gataaagttg tggaagtaaa tgaaaaagta gcacaggttg taggattaac
    15241 agcaaatgat tttactaggt cagtagtttt accacaagac aaatttaatg agtttctaag
    15301 attatcacgt gcagatagaa gagacatgtt agagagaatt tttaatcttg agaaatatgg
    15361 aagaagtctt ggagaaaaag tgaaaaagag aaaaaatata cagttacaaa atttaaaaga
    15421 tttgaaatca aaattaagtc aatatgatgg aattacagag gaagtataca acaatataaa
    15481 ccaagaatta atagagttaa aaaatttgga aaaagataag gataatgctt tagacctagc
    15541 tcaaaaatct tatgaagaaa gtaaaacagt atatgaagaa caattaaagt tagaaaaaaa
    15601 tgaacttaga aaaaatgagc ttgatttaaa aaatagtgag ataaaagaaa agattgctct
    15661 tgtagaaaat gatagtaacg ctaaaaaggt agacccatac ataagttcag ttcaaaatct
    15721 agaaaaaaag atagatgaag atagcttcgc agtaagtaat ttagaaaaga aattagcaat
    15781 attaaatcag gagcttgaag ttacaaaaaa tagatatgaa aaaataaaca aaattaagaa
    15841 tgaagaagtc cctaaattga gtgaagaaaa aataagattg caacaagcaa taaaattaga
    15901 agaagagtta gttttattag atagagagtt aaaagagcta aaagaaagtg gaattaattt
    15961 aaataagact aaagttgaat tagaaaaagt aaagcaggtg tcagagtcca gaaaagatgc
    16021 agttactaaa tctataaaag aagttgaagg aaagattgat aaagtaaata taagtgcaga
    16081 attaaaacaa aaaatatttc tagcatatga atacgagaaa gattacaaca acgtattgga
    16141 agaaaaaaat caaaagctaa ataaactaga agaaatactc aaagagacag aaaatataaa
    16201 tttaaaagtt agatatattg ataaagataa gaatgatgta aatcgtaatt tagaaaattt
    16261 atcacttcac ttggatgttc ttcttaaaaa atgtcctggt aagagtgctg atttactttt
    16321 aaaatctgaa tatgttactg aattaagaaa taaagcaaat aatactaaag aaaatgaaat
    16381 taagaaaagc agtatacaag atgaattaaa gataatactt gaaagtaagt ttaatactga
    16441 aagggaagta aatttactaa atgaaaaact tgaaaataat agaaagaaca gagatgactt
    16501 agaaaaagaa ttagaagaac taaagtattt aaatttagcc tctgaactta gacgtgaatt
    16561 aaaagaaaat atgccttgtc cagtttgtgg gtcaaaacat catgaaaatc atgatataac
    16621 taagtatgat gaaaatatat cttttgtcaa agaaaaactg gagaaattag aaaaagaaaa
    16681 aataagtata agaaacaata tagaggaatt aaatgctaaa gtaagtgggt atttatctat
    16741 agaaaaaatg aagactaaag aacttgaaga tgtaaaagga aaactagggg ggattccatc
    16801 tagtcaatta ttaaaaaaac ttgatgaaga acaaagaaaa cttgcattgt taaaatctaa
    16861 tattcaggag tgggagaaag aaaaagagag tactgaaaat aaagtaacat tagctaaaga
    16921 agaaaaaaat aaaattgaaa aagaagaatt aaaaataaga gagagtctga ataattataa
    16981 gaaattaaca agagatttaa acatagaaat agaaggttta gaaaataaat gtaaaaaact
    17041 taaacaggaa tacctaggat taaagacgat tactaaagtc tctaatctat tgtcaaaagt
    17101 aaaagaaata agagagaatg aaaaagaatt agaattacta agtactgggc attcaaattt
    17161 attaaaaaat agagactcac tagatattaa aataagagaa aatgagagta aactacatga
    17221 aatagagata gaattaataa aggctagaga attatatgta gaaaagaaat tgagtagaga
    17281 taataagtat aaagaagtta ttagcataac gaaaggtgat ttagctaaaa atcttttaca
    17341 taatgttgaa gaaaatatat gtaagatatt agaacaagaa gaatcaagta agaaaaaatt
    17401 ggaagagcaa agattagaat atgaaaaaaa cattgctgaa aagcacaata tagatggtag
    17461 acttaaaact gctaaggaac aatataaaga ccaaaaatca acactaaata aactattagc
    17521 agaaaataaa tttgaaagta tatatgcagt aaaaagagct ttattagata ctgatgcagt
    17581 aaaaaaattg attgaagaaa tactagagca tgaagaagaa caaaagttat tatcatttaa
    17641 aataaaatca tcaaaagaaa aattaaatgg aagaagcata aagaaggagt actttgaaca
    17701 gttaaaagat gaaatttata atttgaaagt agaaatagga aatatatcca aagatattgg
    17761 agctaatcaa aatcagttaa taacattaaa agactcttta gataagataa atgattttaa
    17821 taaacaactt aaggtagttg aacacaatgt ggacttattg gaagaattag ataaatgtgt
    17881 acaaggaaat aaatttgtag aatatgtttc tacaaaccaa ttaaaatata tagcgttgga
    17941 agcatcaaaa cgattggatg gaataacaaa aggaagatat gcacttgaaa ttgactcaac
    18001 actaaacttt gtaatgagag ataactttaa tggaggagaa agaagaagca ttgatactct
    18061 atctggtgga gagacattct tgacatctct atcattagca cttgctcttt catctcaaat
    18121 acaattaaag ggaagtgcac cattagaatt tttcttttta gatgaaggtt ttggttcatt
    18181 agatagtgaa cttttagaaa ttgttataga atcattggaa agattgcata gtaataatct
    18241 aagtgtgggt ataataagtc atgtcgagga acttaaaaat agagttcctg ttaagctatt
    18301 agtttcatct agtgaggctg gaataggttc aaaagtaaaa attgaatata gttagaaaat
    18361 atatgttaat tgaatatatt atctaatatt tccaaataat atgtaattgt gatataataa
    18421 aaactaatat taaagttatt tataattaat attaatataa aaacatgtaa gtaggagtgt
    18481 ggtaagtgtt ggaatcgccc aataatttga ttcagattat ttttttaata gtattactta
    18541 tagggtctgc atttttctca gcatctgaaa cggctttaat gtcgttgagt aaaatcagaa
    18601 tcagatatat gcaagatgaa ggagttaaag gagctaagtt agtaagttca ttaatagaaa
    18661 atccaaataa gcttttaagt tctatattgg ttggaaataa cgtcgtaaat atagcagcaa
    18721 catccatatc aacatctttg tttataggat taatgggaga aaaaggagtg gcacttgcta
    18781 cagctgttat gacagtatta gtattaatat ttggtgagat tactccaaaa acaatagcag
    18841 caaataattc agaaaaggtt tctctattag tatctaaacc tataaaagca attatattta
    18901 tattaagacc aatagtatgg atatttaata taattacaaa tattatattt aaattatttg
    18961 gtataacaaa taaaggagct aaatcattca taactgaaga agagctaaaa actatggtaa
    19021 atgtaagtca tgaagaaggc gtccttgaaa tggaagagag agaaatcata aataatgttt
    19081 ttgaatttgg agatatgcaa gctaaaaatg caatggtaca aagaatagat atggtagcta
    19141 tagatatgga agatagttat gatgagataa tacaggtatt taaaactgaa aaattaagca
    19201 gaatgcctgt gtatgaagaa actatagatg atattgtagg aatacttaat ataaaagata
    19261 ttatattttt atctgatgaa gaaatagagt catttgatat taaaaattat atgagagaac
    19321 cttttttcac gtatgagttc aaaaagataa cacaacttct tgaagagatg aaacttgaaa
    19381 aaagtcagat ggctatagtt gtagatgagt atggtggaac atctggactt ttaactatag
    19441 aagatttagt agaagtcatt gttggagata tagaggatga atatgatgaa gaagaggatg
    19501 aaatacaagt tataaaagaa gatgagtata ttgtagatgg aagtactaaa attggtgatg
    19561 ttaatgaact tattggtgta aacttggaat ctgaggagtt tgattccata ggaggtttta
    19621 taattggaca cctaagcaga ttgccagaag aaaatgaagt aattgaggtt gataatataa
    19681 gattttgtat agaaagtata gaaaaaaata gaattaaaaa aataagaata tatacataat
    19741 gtaataatgt tc
//
LOCUS       DAMJWC010000068        19355 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMJWC010000068 DAMJWC010000000
VERSION     DAMJWC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19355
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.068"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(226..1476)
                     /locus_tag="PC503_002909"
     CDS             complement(226..1476)
                     /locus_tag="PC503_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF2528875.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1508..2449)
                     /locus_tag="PC503_002910"
     CDS             complement(1508..2449)
                     /locus_tag="PC503_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF2528876.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2689..3765)
                     /locus_tag="PC503_002911"
     CDS             complement(2689..3765)
                     /locus_tag="PC503_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2528877.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4138..4653)
                     /locus_tag="PC503_002912"
     CDS             complement(4138..4653)
                     /locus_tag="PC503_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF2528878.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5016..6086)
                     /gene="leuB"
                     /locus_tag="PC503_002913"
     CDS             complement(5016..6086)
                     /gene="leuB"
                     /locus_tag="PC503_002913"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF2528879.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6093..6584)
                     /gene="leuD"
                     /locus_tag="PC503_002914"
     CDS             complement(6093..6584)
                     /gene="leuD"
                     /locus_tag="PC503_002914"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF2528880.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6599..7876)
                     /gene="leuC"
                     /locus_tag="PC503_002915"
     CDS             complement(6599..7876)
                     /gene="leuC"
                     /locus_tag="PC503_002915"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF2528881.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7833..9575)
                     /gene="leuA"
                     /locus_tag="PC503_002916"
     CDS             complement(7833..9575)
                     /gene="leuA"
                     /locus_tag="PC503_002916"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF2528882.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTTQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9699..9945)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10093..10539)
                     /locus_tag="PC503_002917"
     CDS             complement(10093..10539)
                     /locus_tag="PC503_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528883.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10560..11279)
                     /locus_tag="PC503_002918"
     CDS             complement(10560..11279)
                     /locus_tag="PC503_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2528884.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11397..12671)
                     /locus_tag="PC503_002919"
     CDS             complement(11397..12671)
                     /locus_tag="PC503_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF2528885.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNVKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12871..14238)
                     /locus_tag="PC503_002920"
     CDS             complement(12871..14238)
                     /locus_tag="PC503_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2528886.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14488..14952)
                     /locus_tag="PC503_002921"
     CDS             complement(14488..14952)
                     /locus_tag="PC503_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF2528887.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14957..15586)
                     /locus_tag="PC503_002922"
     CDS             complement(14957..15586)
                     /locus_tag="PC503_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2528888.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15620..16507)
                     /locus_tag="PC503_002923"
     CDS             complement(15620..16507)
                     /locus_tag="PC503_002923"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF2528889.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16536..17774)
                     /locus_tag="PC503_002924"
     CDS             complement(16536..17774)
                     /locus_tag="PC503_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528890.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18158..19300)
                     /locus_tag="PC503_002925"
     CDS             complement(18158..19300)
                     /locus_tag="PC503_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2528891.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         6224 a         3546 c         1975 g         7610 t
ORIGIN      
        1 aatacacatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac
      121 tattattaag aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa
      181 acaagggcta aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc
      241 atgtaagaat agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat
      301 cttatttgca tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc
      361 tactttcata tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat
      421 aaaatcaatt cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata
      481 gtcttgtaat atagaaatgt ctaatgagtc aacagggtct tctatttcta ataaattttt
      541 atttgctttc attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc
      601 aggtttatat ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt
      661 tataaattct tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac
      721 cattaaattc tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt
      781 ataatttgga tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg
      841 atgaccatct gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat
      901 tatatcatca ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc
      961 atataaaggt tcattattat ccataaaatc attgattata tcatctatca ccctttgatg
     1021 tttgtaagtt acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct
     1081 atcaatttcc ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc
     1141 atcaactgat atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata
     1201 tatatatata cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa
     1261 attttctcgc gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc
     1321 aatttctgat ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc
     1381 ttctttacta ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt
     1441 tggtctaatc gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca
     1501 aaatatttta taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca
     1561 catttactat ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag
     1621 gtgtaggaga aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat
     1681 aaacatctat agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt
     1741 catcaactaa accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta
     1801 tttctttttc agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga
     1861 aatctgcatt ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg
     1921 cctcacccat tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa
     1981 cttcttttgc aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac
     2041 ctttatactt tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga
     2101 atcttgcaag aacaaataat tgacctattg taagctctgc aacagatata ctgcttgcat
     2161 ttggagtatt cataactttt atgccattag cttgagcata tttaacatct atattatcca
     2221 gacctactcc acctcttact atcaacttca actttttacc ctctaatgct ttatctatta
     2281 catctttagt aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat
     2341 ctcctaaaac atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt
     2401 ttctcgctgc ttctttctct attccatcag taactaatat attatacata acaaactcct
     2461 ccaattttta ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa
     2521 aaactttact taatttaact ttctgtttat ataattttca aaatattttt ttattaaagt
     2581 catatcaaat ttttctattg tttgttaaaa atttaatatg taatttttat aaaatattat
     2641 ttattatata ttctaaattt atcttaaaac atacatattt ttacaatatt atttattaaa
     2701 acctaatata tcatcaatat tatctaataa ttcttgtaca tcttcgacag tatagtcacc
     2761 catatgtgaa attctaaaag ttttttcttt taaatctcca tagccatttg ctatttggaa
     2821 tcctcgttct tgtaattttg aatttaaatt tgatacacta ataccttgag tattttctat
     2881 aacagtaagt gtattggata agtgattttc attggtaaaa atttggaagt gttttttagc
     2941 ccagtttcta actaagtttg ccatgtcttc atgtctgttg aatctgttat ctaggccttc
     3001 atctaatata ttatctaatt ggaaatctaa agcgaacatg tgagaaagag atggtgttga
     3061 agggtattgg tagtttttct tgattaagta ttcatacatt gctaacaaat caagatatac
     3121 tcctctaaaa ggtacttgct tagctctatc gattgctttt tgagaaaatg tgcaaataga
     3181 cattcctggt ggtaatccca gtgctttttg tactgatgtt atacaaatat ctattccaat
     3241 cttatcaacc tcgactttta ttccaccggc tgaacttaca gtatctacac agtagattac
     3301 atcctcatac tttttaacaa cttctccaat ttcttctatt ggatttctta ttccagttga
     3361 agtttcattg tgagttacag ttattaaatc gtattctccg gtagaaagca ccttatcaac
     3421 catttctggc gttgttgcct ctcctaattc aactttaaat atatccgctg ggacattatt
     3481 agccactgcc attttgtacc atctatcacc aaaggatcca caggaaaata ctgctgcctt
     3541 tttggatgta caggaacgaa tggagccttc cattaaacca gttccggatg acgtggataa
     3601 aagtatcgtg ttgtttgtat agaatagttt ttgcatcttt tcacttatac tcttttggag
     3661 catagatgca tcttttcctc tatgtcctat cattggtgta gccatctttt gcaagacttc
     3721 ttctttaaca tcaataggac caggaataaa taatttctta ctcattataa ttcccccctt
     3781 tttagtttgt aatatggata gcgtttttac tgtccttatt tttaataact ataatatcaa
     3841 gctgaattaa ctatgtcaac ataaaattta ttttttatat ataatttatt ttatatattt
     3901 tatgaaaaca ttcattttct accttttcat aagtctgaat tttctgaatt attccctcaa
     3961 aaaaaatata ctttttatct atataaatta atttttttag tatgtaaatt ttacgctatt
     4021 acgataaatc tttttagtat aactaattta tttttatctt gtatttttat tgtatttttg
     4081 aattttattt tttctaaata taaaatttat gttttaaaat ataaaatttt tatttaatca
     4141 aagttcaata tattccactt tttctttcga ttcttcaaaa aaccattctt cattagaaaa
     4201 atcaccttct gcaatttgtc caataggcat tttcatatac tttccagttg ctgtcactgc
     4261 tatatctcca tttggtagaa ttatttctcc tgtaccttca aataattttc tgttttcttt
     4321 agttattctt ccaacaactt ttatagtagc atctgttggt actggtttct tatatttcaa
     4381 ctctaaagat actgttactc cccatatttg gtcatcattt atacttacag ctcttccaat
     4441 agtctcatcc aatattgcag cagacatacc tccatgaact ctcccaggat aactttgatg
     4501 ccaatccttt gtattacaaa ttgatacaag ctctccattt tcaagttcat aaaaatctgc
     4561 tttaagtcct agctcatttt gtgttccaca aactaaacaa gatttactac tattttgctt
     4621 cttcaaaact ttatactttg ccaaaaaatc catctcctaa ccgacattag tagtcgctta
     4681 atattaaata attctaaaat atattatata atattaataa aatccctgca aacttctaat
     4741 aataaaaata ggctacttca atatgataag tttaatttaa agtattattt tccaaaaaat
     4801 aactttatca aaatagaaac tcaaagtaga tataaacctc tttttcgtta ttaaaatagt
     4861 aaaaatatat ttgacttaat ataaaaaaga gtgtctcatt aactaataaa gtttattttg
     4921 agacacccct cataaaacaa attatactac aatagatttt tactaattct acaagttata
     4981 tatttaaatt atattattca aattaaacta taattctaaa tttcatttac tattaattcg
     5041 cccatttccc ttgttcctac aacatttccc acaccattat agatatcaat agttctataa
     5101 cctttattga gtacactttg tacagcatct tcaatacact tagcttcttc ttctaagtta
     5161 aaactatgtc ttaacatcat gcttacagat agaatagtcg caattggatt tacaatatct
     5221 tttccagcta tatcaggtgc acttccatgt attggttcat acataccaaa actatcttct
     5281 ctaagtgatg ctgatggtaa catacctata gaacccgtaa tcatagatgc ttcatcagat
     5341 attatatctc caaatatatt attagtcact attacatcaa attggctagg gtcttttaca
     5401 acttgcatag cagcattatc aacatacata tgtgacagtt ctacatcttc aaactcttta
     5461 gctaagtctt ccattatact tctccaaagt cttgaactct caagcacatt tgccttatct
     5521 acacttataa gttttttatt tctatttctg gctatttcaa aagctctctt accaattctt
     5581 cttatttcat tttcgttata tatttctaca tcataagcat tttcgatacc atcaatgatt
     5641 tttcttccac gttctccaaa ataaatgccc cctgttaatt cccttacaac aacaaaatca
     5701 atgcctttct caactatatc cgttctaagt ggtgaagctt cttttatact ttcatacatt
     5761 gtagctggtc ttaaatttgc aaataaaccc aatgactctc ttaattttaa aagaccagac
     5821 tctggtcttt tatctccctt acatttatcc cactttggtc ctccaacagc accaagcaat
     5881 acagcttcgt tttttcgaca agtttcaaca gttttattag gtagaggttc tccagtttca
     5941 tcaatcgcgc atcctccagc taatacatat tcacaatcga atctatgatt aaatttacaa
     6001 caaattttat ttagaacctt tataccttca tctataattt ccggtccaac accatcacct
     6061 tttatgactg ctatattaca attcatactt cactaccccc tatttgcttt tattgagtta
     6121 attaagcctt catttaatat aatattttgc ataaactcag gaaatggttc tgctttatat
     6181 tcttttcctt ttgttatatt ttttatcaca cctgtagaaa aatctacttc tatattatcc
     6241 ccttcatcta tgttattggc agcttcttca cattcaagta taggaagccc tatatttata
     6301 gagtttctaa aaaatattct agcaaaagta gaagcaatca cacaggatac tccactttct
     6361 tttattacaa ttggtgcatg ttctcttgat gaaccacaac caaagttttt agttgcaact
     6421 ataatatctc ctttttttac cttagaaata aatttatcat caatatcctc catacaatgc
     6481 gttgctagtt ctttataatc agctatattt aaatatctag ctggtattat tacatctgta
     6541 tctatattgt caccgaattt aaaaacactt ccattggcaa tcataaattt tacctccctt
     6601 aaattatttc tgatggtttt gatatttttc cagttatagc tgatgctgct gctacagctg
     6661 ggcttgcaag atacacctct gaatcaacat gccccattct tcctacgaaa ttcctatttg
     6721 ttgttgaaat ggatttttct cctgctgcaa gtatacccat atgtccccct agacatggac
     6781 cacaagttgg tgtagaaact gctgctcctg cctctataaa agtggtaata tacccttttt
     6841 ctatagcttc aagatatact ttttgagttc caggaaatat cataactcta actccatctg
     6901 ctactttttt gcctttcatt atctcagcta ctacttcaag gtctgatatt cttccatttg
     6961 tacaagagcc tattacaact tggtctatct ttatatcctt atctatctca tctactgttc
     7021 tagtattttc aggaagatga ggaaaggcta ctgtttcttt tagttcagct aaatctattt
     7081 cgtatacttc atcatagact gcatcttcat ctgcttcata tatatttaca tcttttgtca
     7141 tagttgaaca cttatgtgaa tttatatatt ccatagtctt atcgtctact ggaaaaattc
     7201 cattttttgc tcctgcttct attgccatat tacaaatagt aaatctatca tccatagata
     7261 agtattctac tccatctcca caaaattcca ttgacttgta aagtgctcca tcaacaccta
     7321 tctcccctat tatatgaagt attatatctt taccacttat ccatttattt ggtttattct
     7381 tcaaaacaaa ttttattgct ccaggaacct taaaccaaca ttttcctgta gccatacctg
     7441 ctcccatatc agttgaacct acaccagtag aaaatgctcc taatgctcca tatgtgcaag
     7501 tatgagagtc agcacctata attacatctc cagcagttac tatacctttt tcaggaagaa
     7561 gaacatgctc tattcccata tctcctacat caaaaaaatt tacaactcct tttgattttg
     7621 cgaaacttct tgtaaattta cattgttctg cactctttat atctttatta ggtgtaaagt
     7681 ggtctaaaac catcactact ttagtcttat cataaacatc ttcaattcct aatttttcaa
     7741 attctctaat ggctactggt gatgttatat cattacctaa aactacatct aaatctgctt
     7801 cgattaattg ccctttctta acttcattta atttagcatg tttggctaat attttctgcg
     7861 tcatagtcat ccccattttt tatttcctcc tcaatataac ttttatttat tgcattcata
     7921 agtgcattaa tagctgctgt atttatgttt tccgatatac ttacaccaaa atagacttca
     7981 ttattgtgct ctattcctac ataagctacc cctcttgaat gtgacccttc ctctaatgca
     8041 tgttcccagt aatatctaaa tttataatct ttcatgccac attgctttag tgcattatta
     8101 aatgaatcta caggtccatt tcctatacca acaatccttt gttcatttcc catataactt
     8161 attcttgcag tcatctcaat catgttagta tcattagaat catcattttc atagtttaat
     8221 tcatccattg attttatttt atacttctta actttataag ggctctcaac ttcaatatat
     8281 tctttcttaa acaaattaaa tattgcttca ctactaagtt cttccccaat tctatcagat
     8341 tccattttga ctacatttcc aaaatcagaa tgcatattct taggtatcat aaatccataa
     8401 tctgtttcca ttatataaac agctcctcct tttccagatt ggctatttat ccttataatt
     8461 tctttgtatt ctcttccaat atcatgaggg tctattggta aatatggaac ttcccagtaa
     8521 tcattatctc tgtttttcat tgctatcatg ccttttctaa tagcatcttg atgtgaacct
     8581 gaaaaagcac aatgtacaag attacctgca tatggatgtc tatcatgtac cataagtttt
     8641 gtacaatctt catatatacc tattatctta tctatattgc taaaatctag ctctgggtct
     8701 attccttgtg tataaagatt aagtcccaca tttactatat ccatattccc agttctttca
     8761 ccatttccaa atagtgttcc ttcaagtcta tcggcaccag ccaataatcc aagttcactt
     8821 gcagccgtac aagttcctct atcattgtga gtatgcaaac ttagtataat agaatcccta
     8881 caacttatat ttttacaaaa ccattctatt tggtctgcat atacgtttgg tgttgccatt
     8941 tcaactgttg atggaagatt tattattact tttttttgag tagttggttt ccaaacatct
     9001 atcactgcct cacatatttc aagtgcataa tccatctctg ttcctgtaaa actctctggt
     9061 gaatattcaa aagtaaattc tgtttctgga tattttttta cttcttcatt aaataatttt
     9121 gctccttcaa ctgctatatc tattatttct tgtttactca tattaaaaac cacatctctt
     9181 tgaagaacag atgtagagtt atataaatgt ataattgctt ttttacatcc ccttattgat
     9241 tcaaatgttt tttctataag atgagcccta gattgtgtaa gtacttgtat agttacatca
     9301 tctggaatca tattctcatc tattaatttt cttaaaaatg tatactctgt atttgatgct
     9361 gatggaaatc ctacctctat ttctttaaat cctgtatcaa taagcatttt gaacattctg
     9421 actttttcat ttacactcat aggtgttggc agtgactgat ttccgtctct taaatcgaca
     9481 ctacaccaaa ttggagcctt aaatatttca ttatctggcc atttacgatt tactatttgc
     9541 attttatcat attttttata ctttccacac ttcatgttat ttcccccttt ttctgttttt
     9601 tgtattcagt atacctcata tcgacgcaat cctgcacaat tcataaggat aaatgtcaat
     9661 tttatcatta gaataaaaaa aacctcatct ctaataaaat tagagacgag gttttgctcg
     9721 cggtaccact ctatttagct ttctaaaaag ctcccttagt aatagccaat acaataatta
     9781 taatgactat atttcctata acgtggaatt actccgatta ttctaagatt taaatcttag
     9841 aaaacagctc ctagacaagt tcagaactat caactactaa atcacaccat cctttagctc
     9901 tctgaaagtt tcattgttct tactacttct attcatcact tttttaatca tttaaatttt
     9961 ctaaatattt tgatttaata gttattatat acacattaaa atgtattgtc aacacaaaaa
    10021 ataattatct caatttttta tttttgataa gcaattctat aaaacatgct aactattgaa
    10081 aacagtatga tattatgcct taaacttttt catcttttca tctatgatat tcaataattt
    10141 tttttcatct tccaaactca atgcccttaa tctaatttta taattagatt cgtcagtgta
    10201 tatatttaat atatttttta ctacttctat tttttctatt atcttataat taaacttttg
    10261 actttgttta gattttatac tgaatataca ttgattattt attaatattg aatgattatc
    10321 gagagtaata tatacttttc cctcatattt atttgaaaaa tcacgacctt gtttaaatag
    10381 aaaaactgct gttattatac ataaaatata taatattgtc gttgaatata taaaaattgt
    10441 agctaaaatt ataagtgcta aaaccatata tatagtcatt ccttttttaa aataaccatt
    10501 gtcataataa ttcatataga taaacttatt tttactcaaa ttttttcact tccaagattc
    10561 taaaaattta tatcaaaaaa ttctataatt tcatcttcat gataatttat gactaattca
    10621 tctggaaaat ctactgcttc taaaactttt tctgcatttt caaattctcc tatagaataa
    10681 catatatgag agtcagtacc aagaattact cttgcaccat atgttttaca caatgtcaac
    10741 atatgactta cattttccca agtacccgtt ctatgagagt ttgaacttaa tgatgaatta
    10801 tttatttcta aaaggatatt tttatcttta gcttttttta ctataggttc ataatctaaa
    10861 ggatacctac tgtcatctgg atgtccaatt atttttacct taggtttatc cataactttt
    10921 aaaatagcat ttgtattttc ttcttttgta ccagaagcta tacaaggtct atgcaaactt
    10981 gcgattatat aatccaaatg ttgcaacata tcttcttgaa catctaaatt accattataa
    11041 tccattatat ttccttctat tcctctaaga atctttacgc cttgcacttc acgtggaagc
    11101 aaatgcaaat tataaaaata gaatggatgt ggtcctcctg gcatattagg tccatggtct
    11161 gatattccta agtattttat attcttctta ctcgcctctt cgacattttc cttgaaagta
    11221 ctatgtgcat gtccacttat tagagtgtga caatgtacat ccataataga ctttttcatt
    11281 aaatttcctc ctaatatttt acataaattc gtgaaaatag ctaaagggct atttcaaaac
    11341 taaagctgtc ataatagaca gtgtaacgtt ttaaaacagc cccattttca attattttac
    11401 acttctaaat ctttaaattt atctttaaat aattctccaa tacttcctaa agattcctct
    11461 acttctaggt attctgttat atcctcttct ggctctctag ttgcttcttt tattgaaacc
    11521 aacattctct tagtctttgg tttaaaatca agaatcttaa ctttaacctc atctccaata
    11581 ttaacaacat tagtaacttt agccactcta gtatcactca attcagatat tggtaaatac
    11641 gcatctacac cttctttaat ttgaacaaaa gccccttttt ctattattct aagaacttta
    11701 acattgacaa catcatcaat ttgtacttct tttgctatta aatcccaagg gtcattattt
    11761 atgtctttta atgccaaggc aattttttta gtctctttat ttacatccaa cacataaact
    11821 tctacttctt gtccctctga aacaacatct tcaacacttt caactcttgt ccaagctaaa
    11881 ttatttatat gtgctaatcc ttcaatccca ccaatatcca caaatgcacc ataaggcatt
    11941 atctttgtca ccttaccatc tcttttttgt ccaacttcaa gagaattaaa taagtcttct
    12001 ttagctgctt tgatacgagc tttttcttct tctctttctt gcttaattct tgctctttca
    12061 gcttcttttt ctgccttaat ttgagctctt ctttcttctc tctctttatt tatacgctct
    12121 tgtaatacat ctctatgaga tgctacaagt ctattttttc taacatccaa ttcttttata
    12181 taaacttcta agttaagacc aacaaattta gatgtatctg taataaattt tgtatcaagt
    12241 tgagaaattg gtataaaaaa tgtatatgta ttgtaattag caaatacacc tttatctata
    12301 ttcttttcaa catttacagt tattattcta tgttcatcat aagccttttg taactcggca
    12361 aaatcatttc ttttgtcaag ttgtaattta gataaagtta ttgtaccatc tttttgagat
    12421 acttttgtta ttacagcagt tatttcatca cctatgtggt atatatcttc tatatattga
    12481 tttttttcta tgttcaattc acttataggt attattccat caaacccata gtctaatcct
    12541 aattgtactt catcatttct cactgcagtt atttttccag ttgtcaattc tccaactttc
    12601 actttgctga atacttgttc ttgctggtca agtaattctt gcattgttaa atcattttcc
    12661 attataaaca tcctttcctc ttattgatta tcatatctgt aaatattata ccattaatat
    12721 tgcaaatact tacatttttc ttactataat ttttaaaata aattcaactt catatattta
    12781 tacattatag aaaatatctt attaaattaa aatacaaatt ctaattttta tctaataaaa
    12841 tattttcata aaaaatttat attgtatatc ttattctttt attgctttag gttttgatag
    12901 aaaacattta taaaatataa agaaagaaat tgctgttata gtagcggctg ttatatctgc
    12961 aactggctct gctaaaatta ctgcaaaaag tttttcatta aagaatgttg gaagtataaa
    13021 tattaaaggt attaaaagta caatctttct aagtagagct aaaaccaaag atattgttgc
    13081 ttttccaagt gctaaaaatg tctgttgaca agctatttga atcccaaaca taaaagcacc
    13141 agcaaaatat atttttatac tccaactagt catactaagt aactgcggat tcttattaaa
    13201 tatactaaca aaaaatgcag gaaatatcat taataaaagc cataaaatag tagaatatgt
    13261 aaaacatgac aataaacaca acttaaatgt cttttttact ctatcaagtt gacctgaacc
    13321 ataattataa cttattattg gttgtgctcc ttgtgtaacc cccatattag gaagcataag
    13381 aatttgcatt atactgctca ttatggccat tgaacctact gctaaatctc ctccatacat
    13441 ttgtaattta ctatttaagg ctataagtac taaactttct gtagattgca ttataaatgg
    13501 agagattccc aagccaagca ctggtaagat gatacttgct tttggtatca tatacttctt
    13561 ttttatttta agtatacttt tctttccaaa gagaaacata agtacccaaa tagcagaaac
    13621 gccttgtgca attatagtag ctaatgcagc tccttttaca cccatattaa agccaaatat
    13681 aaaaatcggg tcaagtatta tgtttattaa agcacctata gcaactgtca tcattccagt
    13741 tgtagcaaac ccttgggtat ttataaaagt attcataccc attgaaatct gaacaaacac
    13801 tgtacctatt aaataaatat ttaaatagtc cattgaatat ccaattgtag attcacttgc
    13861 tccaaacatc caaagtaaag gctcttttcc aatcttaaaa cctatagtca aaagtattgc
    13921 taaaatcacc aatacagaaa aactgttact cattattttc tctgcctcat cattgttttg
    13981 ctcacccatt tttatagcag ctaatggacc tcctcccata ccgattaaat aactacatgc
    14041 agttattata attattattg gaaatgccac tccaacacca gccatagcaa cttctccatt
    14101 ttccattcta ccaataaaaa tcctatcgac tatgttgtat aaaacattta caatttgtgc
    14161 gataatagca ggtgtagcaa gtttaaataa taatttaccc acactttcac tacctaagtt
    14221 agtgtttgaa ttttccattt taaaacctcc tcaatccaat aattaaaatg tatcactaaa
    14281 attttattct atataaaaat ttcattttat tagcagacaa atttagagta ctttccctac
    14341 aagtaatact atactatatt tcttttgcca tagtaaacat tttagaacta actgaagtta
    14401 aatactttat ctcatttttt atttattatt aaaaattttt cacatatact cataaaaaaa
    14461 ctatccaagt atattactta gatagtttta tattatatgt aaagaaagag ctgaaactat
    14521 aacccctgat aacaaattgc caagaaatac tcccataaaa gcatctttta ttctcatttt
    14581 taatatggaa gctatagcag atgcagtcca tgttcctgta gttggcagtg gtatacctac
    14641 aaatagtatt ataccaatta tcgaaacact ttttaatttc ttcattcttg agtttatttt
    14701 tctatcaatt acatcagcaa tccctttaaa tagtttcttc cctcttaaaa attgtaatac
    14761 atgtctgaat gtcaatatca agggaatcga taccaatgta gaacctatta cactaaatac
    14821 ataaacccat ataggattta agcccattgc aatacctata ggaatggctc ccctcaattc
    14881 tgttacagga accatagata aaattaatat gtgtaaatat cccaaactat tccctcctat
    14941 tctaagtgac attaagttat gaatttattt gctctataac ctcaccatcc tttttactaa
    15001 ctaaaaatgc atttttagtc aatgaaagca ttggtaaatc actcttagag tctgaatatg
    15061 catatgaatt ttcataatca atctctatcc caagtttacc taatacagcc tttattcttt
    15121 ttactttttc aattccctta cagttttctc caatgaattg atttttatat cttgaatttt
    15181 cataaaaaaa ctccgtgcct ataacctcgt ctgcaagacc ataatactta aaatatttca
    15241 tatatgcata tggagatgca gttatcataa ttataacatt atcttcttct ttatttttgt
    15301 aaataacctt tttcatagat tcgttaattt ttttcattat gcaatcatca aaaaactttt
    15361 ttaaatcttc ttcactaaaa tctactattg gataaaagat tgcctctttt gccttcttca
    15421 agggtatcat tctaattaaa tacataaata gaataaaaat aatgtatggc aactttataa
    15481 tagttttaaa ggttttattt tttaaagagt aaataaaaaa atctatcatg ctatcagtat
    15541 ttataacagt ataatctaca tcaagtaata atacactttt tttcataagt atttccccat
    15601 cctatcacta aaaatatcac taaaaaatca atattattaa acatgtaatt atccataaga
    15661 ttacgtttat ttttaaagca ttatctttta ggacaatatc agtaggatta ttttcatttg
    15721 tagtgttaat tatataatta tatctaagta caccataaac tacaaatatt gttgtaaata
    15781 tcatatgtgg cttttctgga ttacttgtag aatacaatgc ataacataca attgtagaac
    15841 ttaatataac tatcatcatt tgatttagat tttctatgtc ataatcttcc aatatttttc
    15901 tatgttcaac tgcatcatct cttagagttt ctatttcttt tttacgtttt ccaagagcta
    15961 agtacagaga taagaaaaat gtacataaaa ttatccaatt tgataaacta acacttatgg
    16021 ctacacatcc tgcataaacc ctaagtataa aaccaagaga tattgaaaac acatctaata
    16081 gtattatatt ctttagttta agagaatata atatattgtt tatcaaatag agactgagaa
    16141 ttatagaaag attaaaacta acaactgttg ataaacagac tgaaattaac gctaatacta
    16201 caaatagtat attagcactt tttttgctta ttcttccact tgccactggt ctattacatt
    16261 ttttaggatg ttttttatct ttatccatgt ctatagcatc attcagtgca tatactgatg
    16321 atgacattag gcaaaaacac acaaacgcaa taaacgtatt taaaaataaa tttatattta
    16381 gtatgttgtt tgaaaaaatt atagctgaaa atacaaagaa attctttata tattgcttta
    16441 ttctcattaa ctttatataa tctgaaattt tagtaagaag ccttatactt gtattggtct
    16501 gtttcataaa cttactaccc tttcaatatt attttttaaa caggatatga ttttatccct
    16561 atgtttaaaa tttctataaa tccattgaca ttactgatta ctatagtaac caataacagc
    16621 gatagaaata tattatacat attcttttca ttttttctaa gggctttcgt aaagtaagcc
    16681 aataaaatta taactgcaaa actaaaattt atagccataa tacttgaatt gactagatta
    16741 tatcctacta taccatgtaa agttagattg aatataatta ttcccataca tagcttagga
    16801 actctttttt ctgaattttc aataactgat aaaacacaaa aacataaagc taataatgta
    16861 agaattactg gtattgtagc aacttctcca ttttgcaaaa ataacccttt tttaatactt
    16921 gctccaggaa aataaaaaac cgaatacaat aatctctcta taatcattgc aatcttttcc
    16981 aaaattggtt ctccacttat aaatttcgta tcatactgta ttacatttcc aaggttcata
    17041 aaactctcat aagacttcgt tgaaactaca caaatatatg ccattaggat aaatgtaatt
    17101 aaatgtttta acatttttcc tatttttaat ttaaactcaa atatcatatt aaaaaaatac
    17161 aaatatatat tactaatagt tattccaaat agaggaatag ctgctaattc taccaaataa
    17221 gaattttttc ctttcatctt atttgcaata actatgaaaa atattaatga aaattggcta
    17281 tatataaatc tctctacatt taaagtcata aataactgtg gaaaagaaaa tatcattatc
    17341 atagtaagta aaattaaagt taatctctgc atttttatct ttttaatatg attaaagact
    17401 aaagttattg acatagcact agttattatt tgtagacaaa ttagtccaaa cccataggca
    17461 ctattaaaat ctgttgtccc aggatttgct attgaagtac aaaataggta tattggatat
    17521 gcaaaaattg atataattgc tgaaaacaat atatgcttac tattgtcttg acttatagca
    17581 aatacattta aattgaataa aactcctgta tctgtatcta acaatacatc ataagtattg
    17641 tttaaatcat aaaatatagt agtcttagaa aaaaatatct tagttattat taagtaagtt
    17701 attacaacta atataaacaa aaacatctcg tttttatatt ttaatatttt actcatcaat
    17761 atatcaccat ccattcatta tataggattt gctgacacct acaatttatt ccttatattt
    17821 aatagccatc ttcataatgt tcttacttgt tttattgtaa ttgaataact ctttatttac
    17881 aaccacaata tttactttat tgatgttata atcagtcaag tattgtttat ataacataga
    17941 ttagtgttgt ataaaatgag aatttgtaag caatattaat gtaaaatatt tgaaaaactt
    18001 tatataaaaa tatacaatgt tacttatgga attaaactat aacaaattaa agcataattt
    18061 aaggagacaa aattataatc tgtctcctta aatattaaaa ctatatttta aaacattact
    18121 aaatactata caaatttcaa atatagtata aaattaatta gactttaaca ctattagctc
    18181 catcttcttc ccatttttta atttctttta atctatctat tataggtaaa tgctgagtac
    18241 attcaacttc acattttcca caagatatac attctttagc ttttgcctta ctattcattg
    18301 tgtaattcca atgtcctaag ccataaacta actttgtcat ttcttcatca ctctttttaa
    18361 acatctgctt ttcattataa aaaagcatat aggctggggt attaatacct tttggacata
    18421 ctttacaata accacaacct gtacatattt cgttcatatt cttatttaat ctagtctcaa
    18481 tatcatgtat atcctcatct gaataaattc tattttcgtc tgcaatttta catgcatcat
    18541 ctatatcttg ttttttatta aaccctatca aagatatact tatttgtgaa attcctatgt
    18601 tgaatcttaa agctgattct atagtacttt cgccatcttt tgatagaaaa gaaagttctt
    18661 tattatactt tggaatagtt ccaccactta atggattcat tgccacaaca ccatatccat
    18721 tatcaacagc atatttggca ccttttagcc tatatggaaa gtttaatata tttattccca
    18781 tagttacacc ttcaaactta ttttcactta gaatatctat aacctcatct cctggttgat
    18841 gagatgaaaa tactatatgg tctatcaatc cttcttcttt acatttcaat aatccttcat
    18901 attgacctcc aggtctcatt gctagttcgt aatgttccat ctttctaata ttccaaacat
    18961 gataaaaatt tattttagat acgcctaatc gttctattga tttttttaca gcctctatag
    19021 ctttttctga tgtatcacat gcttttggct tttctttagt tgatacataa aaatcggtct
    19081 taccttcctt tatcatttgt ctaaaggcta gtccaaatat atcttcactt ctgtcatcac
    19141 aataccctgg tgctgtatca aagtaattaa tacctttttc atacgcatat ttgactaaat
    19201 cagcattttc ttgattactt ttttctaaat caaaccttaa tcctccatag ccaactactg
    19261 aaaccatttt ccctgtcttt ccatattcaa cgtatctcat tgtaaattcc tccttagata
    19321 tattaagact taatttcttt atagaaaata ttata
//
LOCUS       DAMJWC010000069        19334 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMJWC010000069 DAMJWC010000000
VERSION     DAMJWC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19334
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.069"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            335..913
                     /locus_tag="PC503_002926"
     CDS             335..913
                     /locus_tag="PC503_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2528892.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            952..1530
                     /locus_tag="PC503_002927"
     CDS             952..1530
                     /locus_tag="PC503_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2528893.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1616..2245
                     /locus_tag="PC503_002928"
     CDS             1616..2245
                     /locus_tag="PC503_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2528894.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2235..4994
                     /locus_tag="PC503_002929"
     CDS             2235..4994
                     /locus_tag="PC503_002929"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2528895.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     LKKTA"
     gene            5081..6643
                     /locus_tag="PC503_002930"
     CDS             5081..6643
                     /locus_tag="PC503_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2528896.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6644..7780
                     /locus_tag="PC503_002931"
     CDS             6644..7780
                     /locus_tag="PC503_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2528897.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7844..8920
                     /locus_tag="PC503_002932"
     CDS             7844..8920
                     /locus_tag="PC503_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2528898.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDFMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8898..10136
                     /locus_tag="PC503_002933"
     CDS             8898..10136
                     /locus_tag="PC503_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2528899.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10190..11278
                     /locus_tag="PC503_002934"
     CDS             10190..11278
                     /locus_tag="PC503_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2528900.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11306..12097
                     /locus_tag="PC503_002935"
     CDS             11306..12097
                     /locus_tag="PC503_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2528901.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12212..12766)
                     /locus_tag="PC503_002936"
     CDS             complement(12212..12766)
                     /locus_tag="PC503_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2528902.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12962..14164
                     /locus_tag="PC503_002937"
     CDS             12962..14164
                     /locus_tag="PC503_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2528903.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14221..15201
                     /locus_tag="PC503_002938"
     CDS             14221..15201
                     /locus_tag="PC503_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2528904.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLSEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            15444..16397
                     /locus_tag="PC503_002939"
     CDS             15444..16397
                     /locus_tag="PC503_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2528905.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16387..17343
                     /locus_tag="PC503_002940"
     CDS             16387..17343
                     /locus_tag="PC503_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2528906.1"
                     /translation="MKLSLNQKIYFVSILLFISMALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17340..18095
                     /locus_tag="PC503_002941"
     CDS             17340..18095
                     /locus_tag="PC503_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2528907.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18187..19152
                     /locus_tag="PC503_002942"
     CDS             18187..19152
                     /locus_tag="PC503_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2528908.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAETLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7647 a         1968 c         3457 g         6262 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaaat attaaacata gcttttatac atttaataag gtatgtaaaa tctatgtaaa
      181 aagtaagaaa tataaacatt tttttaatta tattttaaaa atatcaagca agttttcttc
      241 acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa gataaataat tagcaagatt
      301 tgtttagcta aaattaacaa gggagcgata aattatgggt ataacattat caaaaggcca
      361 aaaggttgat ttaactaaag gaaatccagg tcttaaaaat attttagtag gtttaggatg
      421 ggatactaac aagtatgatg gtggatttga ctttgattta gatacagcag catttttaac
      481 aggagcaagt ggaagtgtta ctaatgatgg agattttgta ttttacaaca atttaaaaca
      541 tacatctgga gcagttgagc atctaggaga taacagaact ggcgaaggtg atggagatga
      601 tgaacaaata gttgttgatt tatctaagat tcctggagaa ataagcaaga tttcttttac
      661 tgttacaatt catgatgcaa cagaaagaag acaaaatttt ggacaagtaa gtaattctta
      721 tataagaata gtagataaag acacaaatga agagttaata aagtatgaat taggagaaga
      781 ttttagtata gaaacagcta tagtagtagc tgaaatatat aagcacaatg gagaatggaa
      841 gtttaatgca ctaggttctg gctttgaagg tggtcttgct gcattatgtg gaaactttgg
      901 aataaactta taatttcaac tataacaata aactaaaggg ggatattttc catggctata
      961 gtattaaaaa aaggacaaaa aatcgattta actaagggaa atccaggtct taaaaatata
     1021 aaacttggac taggatggga tacaaattca tttgatagtg gctatgatta tgatttagat
     1081 gtaagtgttt tcatggttgg agaatctcaa agagttgaaa aagatgaaga ttttatattc
     1141 tacaataact taaaacatcc atctggagca gttgaacact taggtgataa tagaactggt
     1201 gaaggtgatg gagatgatga ggaaatatta gtgaatttag agacaatgcc aaagcatata
     1261 caaaagatag ctgtaacagt tacaatatat gaggctgctg aaagaagaca aaattttgga
     1321 caagtaagta actcatatat aagagtatta aattctgaaa atgatgaaga aatattaaga
     1381 tatgacttag gtgaagaatt tagtatagaa actgcaatta cagtatgtga gatatataag
     1441 tataatggag aatggaagtt tagtgcagtt ggagcaggat ttgaaggtgg cttagaagca
     1501 ctttgtagaa actatggctt aaatgtttaa tttaagcaat ataatatatt aaatataaat
     1561 aacctataca aataatgtat aggttatatt atataaaatt ttgtggaggt ttagtatgtc
     1621 gattaattta tcaaaaggtg ataaaataga tttaaaaaaa tctaacccag gactgagtaa
     1681 catacttgta ggtctaggat gggaccctgt gcaacaatct ggtggaggtt tttttaaatc
     1741 gttatttggt ggaggacaag ctgatataga ttgtgatgca tctgtattta tgcttaatca
     1801 agaaggtaaa ttaagtggaa taaaagattt aatttatttt ggaaatctaa aaagtgcctg
     1861 taaatcagtt ttgcatacag gagacaatct aactggtgag ggtacaggtg atgatgaaca
     1921 aatcctagtt aatttggata aagttccatc aaatattcat aaattattgt ttgtagtaaa
     1981 tatatacaat tgtgtagata gaaaacaaca ctttggaatg atagaaaatg cctatataag
     2041 agttgaagac caaggtaata agaaagagat agcaaaatac aatctatctg ataattattc
     2101 tgaaaaaact actcttatag taggagctat atatagaaaa gatggaagtt ggcaatttaa
     2161 agcaattggt gaaggaacaa aagatgcggg tcttaaagaa gtaatgcaaa atttagacag
     2221 gattgagtgt gcatatggaa tttaataatg atatcaaata ttataatgta gataaagaag
     2281 aagttacaaa agacttatct gttaatcctg aaaaaggttt atcagaatca gaagtcaaga
     2341 ctagaagaga aaaatatggt ttgaatgaat ttactccaaa agaagagggt agtttttggg
     2401 atgatttaaa ggaaagttta agtgaaccaa tgatagttat cttgattatt gcagcagtag
     2461 taagtgcagt aattggggaa actcatgatg caatagggat tgtaggtgct atagcaatag
     2521 gtatagcaat aggtatgatt acagaaggtc gttctaagaa agcagcagag gctctttcta
     2581 agttgactga aaacatagaa gtaaaagtat tgagagatgg ggaagtacat caaatttcta
     2641 agagtgaatt ggtaccaggt gatatagtat atattgaaac tggtgacatg gtacctgctg
     2701 atggtagact tatagaaagt ataaacctta aaattagaga agatatgtta acaggagaat
     2761 ctgatgacgt atctaaaaag tgtgatgtag tagtttctat ggaagagata gaatctaaag
     2821 gagcagtagt agtacaggag ccaatacctg caaaacagat aaatatggtg tttggtggca
     2881 cacttgtagc ttatggtaga ggagctctag ttgtaacttc aattggagat aatagtgaaa
     2941 tgggtaaaat tgctcaaaac ttatcagaaa cagatgagca aactccactt cagataaaac
     3001 ttggaaattt aggtggtttg atagccaaag tttctagtgc agtagcagga ttactattta
     3061 tatttatggt tttccaaatg ataagtaaga atgtattaaa tgtagatatg tctggaatat
     3121 taccgttttt agaatcaata gacccagtta aaacagcatt tacagtatgt gttgcgttga
     3181 tagttgcagc agtgccagaa ggtcttccaa ctatgataaa tatgacactt gcaataacaa
     3241 tgcaaaaaat ggctaaaata aatgcattgg ttactaaaaa agaagcttgt gaaacgatag
     3301 gttctgtttc tgtaatatgt tcagataaaa ctggtacatt aactgaaaat agaatgactg
     3361 tagaagttgc atatgttgat ggcagatata ttgaaagttc agaagaggaa ataaatagtt
     3421 attttgaaga aaactgtatg ataaactcta cagctgatgt agagcacaat gatggtgata
     3481 ttaagtattt aggaagtgct actgaatgtg cattgctttt atattacaaa aacgtagatt
     3541 atagacaagt tagaaaaaat tctaatatag tagctcaaaa tccttttact tcagattcaa
     3601 agagaatgac ttctgttata ggtcaagata atcatcatgt actattatca aaaggagcac
     3661 cagaagtctt acttgaatta tgttcacata ttcaaagagg aaaagacata gttccattaa
     3721 ctgaaaatat aaaacatgag attttagaag aaataaagaa attgcaaata aaatcaatga
     3781 gaactttagg gtttgcatat aaagaaatct cacaagctga agaagaagca gcagtaactg
     3841 ctgaaagtga tgctatgaat gtaagtgcaa tggaaaacaa tttagtattt agtggttttg
     3901 ttggtataag agacccactt agaaaagatg ttatagagtc tgtaaataca gcaaataaag
     3961 ctggtgtttc tgtaaaaatg cttacaggag ataatataaa tacggcaaga gctataggtg
     4021 aagagttagg cctattaaaa aataatatga gagtggttga agcttcatat atagatactt
     4081 tagatgatga agaattaaaa caagagatac aaagtatttc aatcgtggca agaagtaaac
     4141 cagatagtaa aatgagaata gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa
     4201 caggtgatgg tataaatgat gctccagcac tttcaaaagc agatgttggt atagcaatgg
     4261 gtatatctgg tacagaggta tctaaaaacg cagcagacat aattttaact gatgatagtt
     4321 ttagtaccat tgtaaaaggt attaaatggg gtagaggaat ttatgataac ttccaaagat
     4381 tcgttcaatt ccaattaact gtaaatgtaa ttgcattttt agtggctata atatctcaag
     4441 ttatgggaca agagatgcca tttactacaa tacaattatt atgggtaaac atcattatgg
     4501 atggaccacc agcactagca ttaggtttag agccagttag ggaccatgtg ttaaatagaa
     4561 aacctgttga tagaaaagcc aatataattt ctaagtcaat ggtgtataca atagtattaa
     4621 atgcatttta tataacagca atactaatgt tacaatctac atttaatttc ttaggagttg
     4681 atgaagcgca taagggaaca gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg
     4741 catttaactg tagagagttt aatgcagata gtatcttccc taattttaca cataacaaat
     4801 tagcactaca aataatagtg ttgacaggaa ttgcacaagt aatatttact cagctattcc
     4861 aagatttctt taactctgta gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag
     4921 cagcaagtgt aattgtggtt aatgaagttg taaaatgtat aataagactg gtaaaactaa
     4981 aaaagactgc ttaaaacaaa ttttttagaa gaaaacagac tgactcaaaa tatgaatttt
     5041 gggtcagttc tgaataaaca tttaaattgg gaggatagtt atgggtgact caaaggtatt
     5101 tgaaaaaata ttctccagcc aatcagatag aggaaattac actccttcaa agggatatct
     5161 aagttatttt atttcgtata ttggtttaga agatgaagtt ttgtacaatc tcgagatatt
     5221 taagacaaaa caaaatattg atagcaaaaa agatattgct ttatttactg atgttatagc
     5281 aaatcctagt gattttgata ttataaatta ttttaaaagt ggacttcaaa aatatagaac
     5341 tagcatggaa gatgtagata taaatatttt gggatttgaa gagattgatt ataaaataaa
     5401 gcaagcaatg gatagagtgt taaaagaaga ggaaaaagaa tttactaatg atagagttaa
     5461 acaaaatttt atagtgaaaa taatggcatg gataaaaatt tatatcggtg ctttagatat
     5521 aaataaaaat gaagctccaa aagtaatatt ttatggagat ataaaaaaac atgaagttta
     5581 tttactctta atattatact tggcaggttt tgatgtttta tatcttaatc caaattcaaa
     5641 gagtaatata gatattttaa aatcagaaag atacaatata gagtttgaag aagccaacat
     5701 aatagaagaa aaaatttctt ttgaagaaag ggttatttta ggggaaaaaa tagataaaag
     5761 ttctgtaaaa aaagctttta ctgttggggc agaagcatca aagcgtataa gtgaggaatt
     5821 gttaaatgat gcaggattta taaaaccttg gcaactccaa gatagaaaaa taaaaaatct
     5881 acttctaagt tcaactgttg atgaaatatc aatatactgg aatcaaccac ttaaattaag
     5941 accaggattt aagtttaatg atgctattgt agaagctcca aattttcttt ctaagattaa
     6001 tggaatatat aacgataaga atgaatatat taagttttta gatttattaa gagattcgga
     6061 aagttcaaca tttattgaat ttaatggaga tgtagataga ttttcaaaag cttttacaag
     6121 agaagctttt agtttatcct ttttattgga ttcaaaaggt gcaatagata aaaactctgt
     6181 tttaaataat aaagattatt ccatatcaac actagcattg aatcaacaaa ttatgatttt
     6241 agagaaagtg gaagagttgt tagaaggaag tatgtttttg aatggtttaa gtggagaaga
     6301 caagataaaa ggtctattta cagtacttca catggataag aaatttgttc atatgatgaa
     6361 caatttcgat tactcactta taaacccaaa attgattata tacatgtaca agagtattgt
     6421 atttgataaa gaaatagttt ttcttatgct tttacttagt aagattggat ttgatattat
     6481 catattatgt ccaggaggag aaaacaatat agagaatgtt ataaataacc aattgattga
     6541 tgtacacaga ttggataaaa tggtatatga ccttaaatta aattcgcttg aaaatgatat
     6601 acctttactt aaaaaaattt ttggaaagag gagacgattt tagatgggga taaatataaa
     6661 tagtttttca aaagataaga actctgtaga ggttactgaa aatttgccta cagcagttca
     6721 agaagaaaac ttcgatataa tggaatatac aaataataaa aaaaatgaac tgagaaagtc
     6781 taaggaagtt gaggcattga catctcttat agaagtagaa aatccagata cgattttaca
     6841 gtttggtagg aaagcatctg aaggagtagc aagagtttct gatagccttt taaatacaat
     6901 aaaattaaat agaaatgaag aaaattctaa aatgttggtt catttaacta aaataatgga
     6961 caagtttgat ttagacgatt ttcaagaaac taaggaacca aatttcgttc aaaaactttt
     7021 caaaaaagct aataatgcca ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga
     7081 agttgagaaa attcaaattg agcttgaaca atacgaaaga gatatagcac tttctaataa
     7141 gcaaataggt gctatgttaa atgaaaactt tgagttttac aatgaacttc aaaaatatat
     7201 tgttgctgga gaaatggcaa tagaagaaat ggataatgaa atactacctt tctttaaaca
     7261 aaaatcagag actagtggag accaaatgga tgttgtcaat tatcaagaac tattaaaagt
     7321 ttatgatatg ttaaatcaaa gagtctatga tttaaggata gcagaaaata tagctatcca
     7381 aacaatacct atgcttagag gtatgcaaca taataattat ggtttaatta gaaaaataaa
     7441 tagtgcattt gtcgtaactt taccagtatt taaacaatgt ttatctcaag ctatattact
     7501 taaaaagcaa gaattacaag caaaatctct aaaagcactt gatgacaaaa ctaatgaatt
     7561 attgcttaga aatgcacaaa atgtaagtac tcaaagtgca caaatagcta gaatggctgg
     7621 aacaagttct gttcaaatag aaacattgga aaaaatgtac aatactatca agtctggtat
     7681 agatgaaact atgagaatag aagaaaacaa tagagcttta attaaggata atacaaagag
     7741 attggaagaa ttaaatacga ctataattta taataagtag tattatatta agggctaatt
     7801 tgtataaagt tggccctttc tatgtatatg aggaggctag acattgaaat atttcgatta
     7861 tatctgcaaa gatgatttgg agagaatttt tttgaaggag ccagaagatt ttagtgctaa
     7921 gactgaaaaa gatgtgttga aatatgcact gggcgctttt ttatacgttc cagctactca
     7981 atataatatg atttataaga gtattatagg ggatgttaag ggagttagac cattagctat
     8041 ttgtttagaa gatgctgttg gagtaaatgg agagttggag gctatagaaa atcttagatt
     8101 aattttaaaa aatattagca atgaaagtat aactaataaa gatggaatac cactaatttt
     8161 tgtaagaata aaagatgtgg agcaactgtt gagaattaaa gagattataa ttaaaaatag
     8221 tcattttata acaggaatat taattcctaa agcaaattcg gagttaattg aaaattgtat
     8281 agaagcttta gattttatga atcttcaaga tatgtatgtt attccgatag tagagacaaa
     8341 agaatttata tataatgaaa aaaaagaact tagttttact aatttgtaca atgctatttt
     8401 aagacataag tcaagaatat taagcattag agtaggcata actgatatat tagggatgta
     8461 tggtataagg agagataaaa acttttctat atataataat ttgatttgtt cttcatttat
     8521 attagatata atcacatatc ttcaaagacc agagttagat atacctataa gtggtggagt
     8581 atcagaattt tttgatatga cgaataagga tataagaaat aagtatatag aagaaatatt
     8641 attggataaa tatcatggat taattggaaa gaccgtaatt catccaatgc aaattcaaat
     8701 tgtacaagcg ctatctacag tatcatatga agattttact gatgctttgg atatactgga
     8761 tagtacagac agtaagtatg gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac
     8821 aaatccacat tttttatggg ctaaaaaaac attgattcta tctaaaatat atggtgtatt
     8881 aaataaagga gtagactatg aagaattgct taaattttaa ttgtgagatt gacattattg
     8941 ataatccatt gaatttagaa ctaaatgatt ttttagacgt aggaataaga aataatagca
     9001 aaagacgttt tttgtttatc tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg
     9061 agatggataa tttgggaaaa ttaatggcta caatttataa tgaaaaaaat aaggaagaat
     9121 caaatggtac tgttatagct tttgctgaaa ctggtacagc tgttgggcat agtttttttg
     9181 attacttatg tggagattat gaatttattc atactactag agagcagttt gacgagttag
     9241 aaaatctgga atttttagag gaacattccc atgcaacaga ccagaattta tactttggta
     9301 tgcttaacaa ctttaaattt ggagatgaga taatattggt tgatgatgag attaccacag
     9361 ccaatacatg catgaatata attaggaaaa ttcaaagcat ttatcctaaa aagaaataca
     9421 ctatatgctc aatactcaat tgggtaagtg atgaaaattt aagtaaagtt actcgtttag
     9481 aaagagagct agattgtaag atagattttg tatacttatt taaaggaaac tttaaatttt
     9541 atatagatga agatattatt tcaaattaca acgataatta tagtattact aaattagaga
     9601 ctatttcaag tgataaagta aatttagtag taaatcatat ttatgttgat ttagaagatt
     9661 atattggaaa taagaaatat gtaaaatata caggaagatt tggaattaat agaagagaac
     9721 aatttagatt aaaagaaatc gttaagagag aaagtaaaaa aataactatg gccagtaaag
     9781 aatctttaaa aaatgaaaaa gaaaagattc tatttttagg tactgaagaa tttatgtata
     9841 tacctatgct gtttgcaaaa gaaaaagaaa atcaatatga tatatactat cattcaacaa
     9901 caagaagtcc aattattaat attgataaga ataattatcc tattaaaagt aaatttatgc
     9961 taaagagttt ttataatata gatattcaaa attatattta caatatagat aaacataatt
    10021 tttctaagtg ttatttattt gtagagctga ataaaagtga aaattcttat ctagaattta
    10081 ttgatataat taaaaaaaca agtataaaag aattaactat agtatgttgt agctaaagtg
    10141 ttttaacagg ataaaatata tcacgatttt aagataggag ttgagtcata tgagagattt
    10201 tagcacgtat tctaaagatg atgttatttt tttattaaaa gatatatcaa atttaattga
    10261 agaagaagga aataaagaaa gagaattaaa aatacaaaat ggtagacatt attcagaaat
    10321 gataccaata gagtatgaag ttagtgaaga ttatctgaat ttatatcatg agaaactaag
    10381 agaaaataaa gataaacttg cattttctat aggagttatg tgtgaaaaaa taattaaaaa
    10441 aaatggaaat gatgtagtac tagtttcact tgctagagca ggaacaccta ttggtatttt
    10501 ggcaaaaaga tatataagaa gcaagtataa tataagttta cctcactata caatctctat
    10561 aataagagat aagggaatag atatgaatgc aattgaatat atagtaaaga atcatccgag
    10621 ctcaaaaatt caatttttag atggatggac tggtaaggga actatatcaa aagaacttga
    10681 aaaagcatgt gatgaactta atgttaaatt taaaaaatat tttgactcaa cacttgctgt
    10741 attagctgac cctgctggat attcaggact ttatggaatt agagaagatt tcttaatacc
    10801 aagtgcatgt ttaaattcaa cagtttctgg tttagtaagt agaactgtac taagagagga
    10861 tttaattggt aaaaatgact tccatggagc taagttttat agacatttaa aagataaaga
    10921 tgaatctatg aactatatcg aaactataga agaatgtttt aaaaatcaat ttaagaatat
    10981 atctgatgaa gttgaaaact gggaaagtga cattataaca agagatggat actttgatgt
    11041 tttaaatata aaagaaaagt ataacataac agatattaac tttatcaaac caggtgtagg
    11101 ggaaacgaca agggttttac ttagaagagt tccgtataag attcttgtta aagacttaaa
    11161 tgataaatct ttagaccata tattcatatt agctaaggag aaaaatgttg aagttgaaca
    11221 aatggattta aaagcctata aatgttgtgg aataataaaa aatatgaaag atatttagga
    11281 aatatattag acaggagaat attgaatgat tgttttttca gatttagaca ggagtatcat
    11341 ttactccaat aaatttttaa atgctgatag taaatatact aatatagaaa tttataggga
    11401 aaaagaaata tcttatatat ctttagatac tataaattta ataaagcaaa tacaatatta
    11461 tggtatgttt atacctacaa ctactagaac agtggagcaa tttaagcgta tagaatttaa
    11521 taaatatggg atttattttc cttggagtat aacttcaaat ggaggagtta tacttaaaga
    11581 taatgaaata ttgaaatcat ggagtgaaaa aatagataaa ctaaaatgtg attatgagcc
    11641 cattgaaagt atgattcata aatttaaaga ctatttgaat gtagatggaa taactaattt
    11701 taaagttgca gaagatacat ttttttatat agttgttgat ttatcaagat ttaatttgga
    11761 ttcaatcaaa gaatatacaa atatattgga atcaaaaaat tggaagtttt atgtgagtgg
    11821 cagaaaaata tattttatac caaaagaaat ttcaaaagaa aatgctataa aatacttgac
    11881 taaagaatta ggaatagaat atttttatgc agttggagat tctattatgg actatggtat
    11941 gcttaatatc tcaaataaat cctatgtatt gaagcatggt gatataaata aaaatgaaat
    12001 agaaaattca tttatatcaa gttctttcaa tggaatgagt ggaactgaag agatactatc
    12061 taacatttta gacgagaact gcctacttaa tatataatga ctgatatata aataataaac
    12121 tagaaaaatc tgaaataaat tatagtaaag tttatcatac taatttattt cagattttta
    12181 tcaatttata tttaagtaag aactcaatat gttaaaatga aggtggagtc attgcccaga
    12241 ctgagataca tacctcatca tcataatttt catacacatg tggtatagta ctgttaaaat
    12301 aaaaactatc tccttcctcc aatagatatt ccttatttcc aagtgttatc ttcattttac
    12361 cttttattat atagccacat tcttctcctt cgtgtgtcac aaattcactg tttttttgtg
    12421 tatgaccatc tagtgtaaca agtataaatt ctattttttt cccagataaa ttaggaacaa
    12481 gaagttcata aaattttgta gaatcattag ttactatttt ttttcgatta tttttcttta
    12541 ctactatatc agagtcttct cttccaatct cttcaaaaaa ataacctata tttatatcaa
    12601 gagcttttga tattttccac attgctacaa tagatggaac aaccatatta cgctcaattt
    12661 gacttattaa gcctgtactt aaatctgaat tttttgctaa agtagagata cttatatttt
    12721 tagattttct aagagatcta attttgcttc caacatctat attcattaga tacaaacccc
    12781 ctcagacatg attataacat ataatttata aagattaata aaataaaaaa aaagttttac
    12841 aatacaagta ttttttatgc tatattgaat tttctgaaaa gatgcattat aatagtatta
    12901 atattcaata tattgaatat tgataacgat attttaattt aatgaaatgg aggtaattaa
    12961 gatgaagagt tttgtaagtc ctgataatat ttgggtatta tgggcagttg taactggatg
    13021 ggcagcattt agtatttatt tggaacaaaa gtacaattgg gcatcaaaag tgtcgggagc
    13081 aataatagct cttgtaggag caatgttatt atcaaatcta aatattatac cagtagagtc
    13141 tgttgtatat gaccaagtat ggggatatgt tgttccttta gccatagctt tattgttata
    13201 tcaatgtaac attaaaaaga tatggaaaga aagtggaaga ttgctcatta tatttcttgt
    13261 aggttctgta ggaactgtac ttggagctat gattggattt ttagcattaa aaaatgtagt
    13321 accagattta aatattgttg cagctatgat gacaggttct tatataggtg gaaatgtaaa
    13381 ctttgctgct atgtcagggg cgtttgatgc gccaggagaa ttagtatcag caacagttgt
    13441 agcagataat cttttaatgg cattatattt ctttgtctta atagctatac catcaattgg
    13501 attttttaga aaacatttta aacatccaca tgtagatgaa atggaaagta taggtataac
    13561 tgaaggagaa acagtagcag caaattattg gggaagaaaa gaaatatctt taaaagatat
    13621 agcaatagcc attggtagcg cctttataat tgttgcagta tctgtagaac tatcaacttg
    13681 gtttaaagct ataataccat tatcaaatcc ttttttagca atgttaaata ctttatttgg
    13741 aaatcaatat ctaataataa ctactttgac tatgttgttt gccacattta tgcctaattt
    13801 ctttggtgat ataaaaggag cacaggaatt gggtacattt ttaatatata tattctttgt
    13861 tgtagtaggt gttcctgctt caataacatt aataattcaa aaatcaccat tactactttt
    13921 atactgcgga ataatggtac taataaacat gctagttaca tttatagttg caaaaatatt
    13981 taagtttagt ttagaagaag ctattcttgc atctaatgca aatattggtg gtcctacaac
    14041 agcagcagct atggcaatat caaaaggatg gtctaagcta gtagggccaa tacttatagt
    14101 tggaacattt ggatacatag tcggtaatta ttttggtctt ttagtaggaa atattttgat
    14161 ataattttac gtgaaaaaaa gttgtttatt agaaagattt ttatttaatt ggaggttgtt
    14221 atgattttcg atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg
    14281 gaaaaagatg tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga
    14341 gctatttttg taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa
    14401 caaattataa gttctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta
    14461 aaaaaatatt cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt
    14521 cttgaaggat taagccatat tggaagaaat atagatttac tagattattt ttataaagaa
    14581 gttggtgcaa gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt
    14641 ttaggggatg aaaatcgtgg tttaagtgaa ataggcaaaa aagcagtcaa taaaatggaa
    14701 aaattgggca tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg
    14761 tctgttgcaa gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct
    14821 aaaagaaatc ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga
    14881 ataaatagtt ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg
    14941 gttgaccata tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt
    15001 gattttagtg attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg
    15061 ccaagtgtag atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa
    15121 aatagaggtt ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc
    15181 tttaaagata tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat
    15241 acaaataata tctacatatt taaattggcg ttcataattt attaaatttt aatgttacta
    15301 gaagtttcaa ttctagtaac attttttatg ttaaaaacag atatagatat gtattgacaa
    15361 tgataattat tattgataaa ctataaaagt gaaaatgata ataattttca ttttaattaa
    15421 taaaagattt ttaaggaggg agaatgaaga aaaggtattt agtcatagga ataataattt
    15481 tgtcttattt ttctttattt ataggagctg aagatataaa tataatgcat atatttgcca
    15541 aaaatcagca taaacttatg atatttatca tgagtagaat accaagatta ataagtatat
    15601 tgattgctgg tgtaggaatg agcatagcag gtcttataat gcaacagata agtaagaata
    15661 aatttgtatc acctacaaca ggtgctacaa tagatgcagc acaatttggg atagtaatat
    15721 gtatgctttt agtaccaact gcctctattt ttacaaagac aataatagca tttgtatttt
    15781 ctcttgtagg gacttttacg tttatgaaaa taatagggaa gttacaattt aaaaatataa
    15841 tctttgtacc attagtaggt ataatgtttg gaaatataat agggtctatg acggatttta
    15901 tcgcgtataa atacgatttg agtcaaaatg ttagttcttg gatgcaaggt gacttttcta
    15961 tgatacttaa aggaaattat gagatattat atatcacaat accccttata atattagcat
    16021 atatttatgc aaataaattt actgttgttg gtatgggtat ggattttgcg acaaacttag
    16081 gtcttagtta caaaagaatt gtcaatatag gtctgataat agtagcactt gttacagtat
    16141 gtgtagtcgt tacagctggt aatatccctt ttataggtct aatagttcca aatatcgtat
    16201 ccttgtacat gggtgataat ataagagcaa gcatatggta tactggttta cttggagcga
    16261 tatttgtact tatatgtgat atttttggaa gaattattat ttatccatat gaaatatcta
    16321 tagggcttac agttggagtt ataggaagta tactattcct ttatttaata ttaaggagga
    16381 atgtgaatga agcttagtct caatcaaaaa atttactttg taagtatatt actattcata
    16441 tcaatggcac tttttataat ttatggaata gacatgaatc atttagaata tgcattatca
    16501 caaagaatac caaaaatatt tgctatggta ttaggtggag gatgtatagc atttactact
    16561 gtagtgtttc aaacaattac aaacaatcaa atattaacac caagtgtact aggtttagat
    16621 tcattgtatg taatgattca aactataata gtattcatat ttggttcaag cagtagtctg
    16681 attataaatg aaaattataa ttttattatt aatgtagcta tgatgattgg agcttcattg
    16741 ttattatata agacgttatt tgaaaaaaat aaaaataata ttttcttttt aatcctagta
    16801 ggaatgatat ttggaacctt atttaaaagt gcaacaacat ttattcaggt aatgatagac
    16861 cctaatgaat ttttagcttt acaaactagt ataatggcaa gtttaaacaa tataaacact
    16921 aatgtattgt taatagcatt tataataatt attgccataa taccttttat atatgatgaa
    16981 ataaagtatt tagatgtatt gtcgttaggt aaagaacaag caattaattt aggtgtagat
    17041 tttgataaag cagttaaaaa aatgataata ttaatagcaa ttttagtctc aatatcaaca
    17101 gcacttattg gacctatgac atttttagga cttttacttg ctaatataac aagagaaatt
    17161 tttaaaacat ataagcatac atacttgatt tcgggttcta tgttgatagg gatgattaca
    17221 ttgataatag gtcaattttt tatacaacat gtatttaagt ttgatacaac tttaagtgta
    17281 gtaataaatt ttataggagg aatttatttt attcaattac tattaaaggg ggcaaataga
    17341 tgatagagat aaaaaatata tttaaaagat ataagaataa aaatgttgta gatgatgtct
    17401 cttttagtat agaaaaggga aagataacat cttttatagg accaaatgga gctggaaaaa
    17461 gtacagtact atcaatagtt acaagactta taggaggtga tggtggagaa gtaataatag
    17521 aaggaaaaag cttgactaat tatagcaata aagaattagc aaaaaaaata gctattctta
    17581 aacaatctaa caatataact ttaaagctta caataagaga attagttgga tttggaagat
    17641 ttccatatag tgaaggtaat ctaactaaag aggatgaaaa ttatattgat gaagcaatag
    17701 aatatatgaa gttgactgat atacaacata agtatttaga tgaattgagt ggaggtcaaa
    17761 gacaaagagc ttatatagca atggtaatag ctcaagatac agagtacata ttacttgatg
    17821 aaccactgaa caatttggat atgaaccatt ccgtacagat gatgaaggta cttagaggtc
    17881 tttgtgatga attagataag actatagtat tagtaatgca tgatataaat tttgcatcat
    17941 gttattcaga taatatagtt gcattaaaaa atggaaaagt tgaaaaagta ggtcgtacag
    18001 atgagatagt aaatgaaaaa gttttagaag atatttatga gatgaatttt aacattaaga
    18061 atataaatgg aaatcgaatc tgtatttatt tttaaaatat tgtatatgaa aataaacttg
    18121 ctatatgatt ttttataaag tttttaaatt aaaataaaga ttaataggag agaggaaaat
    18181 attgatatga ataaaaaagc agcaatagta gcagcagtag ctattatagg attagtgaca
    18241 gtgtttgcat taggtggaag taaaaagaat gaatcaaaaa catcagaaaa ttcaaataat
    18301 actatgaaga taactcataa cttgggagaa acagatgtaa aattaaatcc taaaaaagta
    18361 gtggtatttg attattcggc tttagataca atggatgcat taggtgtagc tgagacttta
    18421 gtaggacttc caaaagcgag tttaccagca tccttagaaa aatataagga tgacaagtat
    18481 gcagatttag gaggattaaa agaaccagat ttagaaggta taaagtcggc aaatccagat
    18541 ttaattataa taaatggaag acaagaagat ttttatgagc aattgtcaaa aatagcacca
    18601 acaataagta caagtaaaga tgataagaag tacttagaat ctgttaaaaa taatatagac
    18661 aaaatagcaa aaatatttgg agtagaagaa aaagcaaatc aagaatttag taaaattgaa
    18721 aagaaaatag aaactttgaa taaaaaagta acagataaaa atttaaatgc tttaactata
    18781 atggtaaatg aaggtaattt aagtgtattt ggtgaagaat caagatttag tatattatac
    18841 aatagttttg gatttgaaaa taaagataaa aatataaaag aatcaagtca tggacaaaat
    18901 attacttttg aatatatagc taaacaaaat ccagaagtta tgttcgttat agatagagga
    18961 atagctactg gcagtgatgt aaaagaaagc tcaactgcaa aatctgtttt gaacaatgat
    19021 ataataaaat ctatggatgc atataagaat gataatataa tatatttaga ttcaccaaca
    19081 tggtatgtaa atgatggtgg tctaacatct ttaaataaaa tgatagatga tgcttcaaaa
    19141 gcggtaaatt aataatccga tataaccaaa atgtattttt tataaaatga ttatcaaata
    19201 aactaggagt ttttaagaac tcctagttta ttttttgcat aaaaaagata tagtttaaac
    19261 aataatatta tctataataa gataaatcta ttcaaaatct aataaaatat gaagttatac
    19321 tagacaaaaa gaat
//
LOCUS       DAMJWC010000070        18984 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMJWC010000070 DAMJWC010000000
VERSION     DAMJWC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18984
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.070"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(60..596)
                     /locus_tag="PC503_002943"
     CDS             complement(60..596)
                     /locus_tag="PC503_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF2528909.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(614..1927)
                     /locus_tag="PC503_002944"
     CDS             complement(614..1927)
                     /locus_tag="PC503_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF2528910.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2282..2722
                     /locus_tag="PC503_002945"
     CDS             2282..2722
                     /locus_tag="PC503_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2528911.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2906..3094)
                     /locus_tag="PC503_002946"
     CDS             complement(2906..3094)
                     /locus_tag="PC503_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2528912.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4116..4511
                     /locus_tag="PC503_002947"
     CDS             4116..4511
                     /locus_tag="PC503_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528913.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4554..6653
                     /locus_tag="PC503_002948"
     CDS             4554..6653
                     /locus_tag="PC503_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF2528914.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNTSTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6878..12088)
                     /locus_tag="PC503_002949"
     CDS             complement(6878..12088)
                     /locus_tag="PC503_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2528915.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12103..14598)
                     /locus_tag="PC503_002950"
     CDS             complement(12103..14598)
                     /locus_tag="PC503_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2528916.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15259..15546)
                     /locus_tag="PC503_002951"
     CDS             complement(15259..15546)
                     /locus_tag="PC503_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528917.1"
                     /translation="MRLNITKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNIFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15566..15841)
                     /locus_tag="PC503_002952"
     CDS             complement(15566..15841)
                     /locus_tag="PC503_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528918.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16496..16675)
                     /locus_tag="PC503_002953"
     CDS             complement(16496..16675)
                     /locus_tag="PC503_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528919.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16960..18435)
                     /locus_tag="PC503_002954"
     CDS             complement(16960..18435)
                     /locus_tag="PC503_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2528920.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
BASE COUNT         6308 a         3320 c         2076 g         7280 t
ORIGIN      
        1 ttttaatata tattttaaat tttctttttt aataaatctt tttcttttaa taaatctatt
       61 taattttctt cttctatatc agagccaaag ggaatccatg cattaccaaa ctctttatct
      121 ttaaataaat aagctaatcc agttatttgc ttcaatctaa gaatttcatc aacttccata
      181 cccaggtgct ttgatatcca ttcatcagat tttccaattt cacaaagttc agttataatt
      241 ttactcatta aatccacatt atgagaacct cttgcacgat tgtgtcgaat agtacttgcc
      301 attctttcat caagagattt atcaattact gaaacaggaa gaagtccatt ttctctatca
      361 tatatatcct cattttcaag cattactcta tatctatgaa aaccatctac aataatatac
      421 ttatcctttt cctcattata ataacagaca attggcattg tatacccatc ttcttttata
      481 cttttataca acaactgcat ttctggtggg gctactgcat ttggattata gtcgttagat
      541 tctatctttt cgattggcac tgcgatgatt ccatatacag gacttttata ttccatagca
      601 tcttaactcc tatctaatga attttttcat atttcttctt aatatattcc gttctaattc
      661 tctgttcttt tgtaggacca aatcccataa atctacacat atggtcattt tttaaaatac
      721 aataacacat tcttttccaa cttggtatat ctttggtaaa tttaatatca tccgtatcat
      781 caggtatatc atccaaaaat atgactctac tctttttatc ttttgtatga tttgaaactc
      841 catttaattc tattttataa ccttttctca acaattcacg tataactatt tctgacaaac
      901 caccacctgt attctgccaa aactcaatag atgttgaaaa ttttttaata tagctattcc
      961 ttatattttc aggtaaggta tcaagcaaaa aatatgtgaa acttttccat gtgtgtccat
     1021 atggcaattt aacactacga tatcccatag cttttgtttt gccataaata gaagtaaaat
     1081 taactccttg tactctagca accaatttca cccatacatc tgggtccaat attctgtata
     1141 aatttaaact ctcttttgct gaatcattaa aaggtgatgc cactctcatt tttcttggag
     1201 ctactccagc tttatagaat aagtcataaa ttttattata gtcatagtca aatttatagt
     1261 gtgctaacca tatatcttct atttcccaat catatatagg agatgccgtc cagacatttt
     1321 taaattcctt agttatccag cactttcctt tatatccatg ctgtttattc acaatagaac
     1381 aataacgttg tagagattct gctgctcgtg ttcctaataa gcaaacaact tttgcacctt
     1441 catgtatatc tctaatccat ctaccaaatt gttttgccaa actttcttgt ctcattttat
     1501 atttataata agtaaaagga ttattttttt gatttattat gtattctttg actggcattt
     1561 cccttaccca taactcttct ttctcatcat cccatggata ccaatacatt tcataatttc
     1621 ctacagcagt tcttgtagcc attggtaaac acacccaata tggttcaata tcttcaatat
     1681 tatcttcaaa tactttttca acatattcag tagtcaaact atattgagcc tcaaaatctt
     1741 gatgaaatac tcctattttg gaacttatat tattctttct cttataatcc aaaactaaat
     1801 ttagcagtaa accactatct tttcctccgc taaaagatac atagatataa tcaaattcat
     1861 taaaaagata agaaagtctt tcttgaaaag cttcaaatac atcggattct aaatatctct
     1921 tatccatttg aattatcccc tttcaattag aagtttataa aaccttacaa tgcaatatta
     1981 ttatgctttt ttagcagtaa tcagcataaa ttatacatta tttaaataca caaatccaac
     2041 taactacata taattataat gtaattatac ttttgtatta taaactatat tttatcatta
     2101 ttttacattt ttttccaata tatataaata tcatattttt ctattagcta aaactaatta
     2161 ctttatattt ctacgtatta gtataataat acataaaaac ttgaataatg cataaaaact
     2221 tgacatactg ttgtcataat tactttgcta taattaaaag taaaaatgga ggtaaattct
     2281 aatgtatgaa cgtatgcttg ataaaagcaa taaaccctgt ttgtcccaaa taatagaata
     2341 tataggtaaa gatggatatg cacgattgtg taagttggaa acttacttga aaactcaata
     2401 taatttatca agagaacttc gatttccttt tggaaacaat tatggttggg gttacaaata
     2461 tagccataaa tcttttcatt tattttatgc tttttttgaa aaaggtgcat ttactgttct
     2521 gattcagata ggtgacaagc aagttccagc agtagaaaaa acgttggtag ctttgacacc
     2581 aaaagctaaa gaactctggg tcactcgtta tccttgtggc aataatggag gctggattaa
     2641 gtatcgtatt ttagaagatg cagacttact tgatattatt caatatataa gagcaaaaaa
     2701 atctccacct aaacaaaatt aacttttatt ttttgtgatt taaatatagt gtatataaat
     2761 tccattcttt ccatattaaa aaataatata aaaaatatct attagtataa cttatttagt
     2821 atgtcttatt ctacttttta cagataatta aaaagtttta tcataaataa atcataacta
     2881 gacatcctag taaatcaaaa ttaatttatt cttttttatt cgaatttttg ataatagtcc
     2941 ctatacatat gccaattatc attccaaaaa ttagaccata acacattgta atacctacat
     3001 ttcctttaga aatacctata gcacaaccta tagccattcc aagtatcatg cctataaaca
     3061 tacatataat aactaaattg ttgtttttat tcatagtttt tctccattca atatatttta
     3121 aattgcctag ctcgccttct tagcttaaaa caaagaaata taaattaact ttctttcatt
     3181 ctaatatctg cctgtataaa tgtcaaacaa cacatttctt gtcataacct cctctttttg
     3241 aagtaagtac aatctcccag acgcaataat atcaatttcc taaaaccatt taagtaactt
     3301 ttatatttac ataatattta caatcataaa ctatattgtt attcatttat acatcataaa
     3361 cactccctcc taatcattat tatacttaaa ataatgttca tttataataa tatatctaac
     3421 gcactttaat tgaaaaaact aaaactttgc ctttcattcc catatataaa taagtatact
     3481 ttttgatgct ctattacaaa tcaactaaat taattgatat aaattatcat tttctgttga
     3541 aaataccatt cgcacatgct atacttaatt gcataaatgg taataaatgt catatgattt
     3601 tacaaatcta ttaataacaa ttattacttt tactgtattt taaagttttt ggactaaata
     3661 tcaagaactt tctaaaatac aaagtacaaa aaatttatat aagttataaa tttatatgaa
     3721 ctagataagc tcaaacaata tgttatgtat aaactgtgta gtattcggtt ataaatttat
     3781 ataaattata taagctagat aaagtattac ctcaactata taagctagat atataaattg
     3841 cttatataag ctagataaga attatttcaa ctatataaac tacatatata aattacatac
     3901 ataagctaga tatataaact gcatatataa gctatataag aattatttca accatataaa
     3961 ctacacatgt aaaattcata taaatttact aatataaatc aaataaaatt actaaactct
     4021 ctaaactaat tttgtaaaac atactctatt tttaacattt gttaccttat acataagtac
     4081 aaacaaaatc taactaaatg aaaggataat gtaaaatgaa tattttaaaa atgaaaaaaa
     4141 cagggatatt tttaggagga gtactttttg gtactgtagg tgttaagata ctttcaagtg
     4201 attgtgttaa aaaaacttgc actcgtgcaa cagcaggagc attgaaagtt aaagattctg
     4261 ttcttgaaac aactacgaaa attcaagaaa atgtagaaga tattttagct gaagcaaaag
     4321 aaatcaacga gcaagaagac ttatctacat ctaaggtaaa cgttgtacaa gatactctta
     4381 aatgcgaaca agaagttctt aaaactgaaa ctataaaaac tgtagaagat actaattcta
     4441 atagcattaa atgtgaagaa atcaaagata acgtaattga agaaaaaaat agtacttgta
     4501 caacagaata aatttaatga ttattatgat taataatatc aggaggaagt aaattgaatt
     4561 tttatataaa acacgaaata agaggtcgta tacgctttga cttacaactt ggcaaattaa
     4621 acaacaagca gtccgatact ctcttatatt atttaacttc tataaatggt attaccaaag
     4681 caaaagttta cgatagaact ggtgatgcag tcatttatta cactggtgaa agagaataca
     4741 taataagaga aatcactaaa ttcagtttta acaatagcaa aatagaaaac ctagttcctg
     4801 aacataccag cagggaatta aacaattatt atagagacaa attagcaaat aaactgctag
     4861 tcaaaagtat ctccaaaata ttttttccaa agtccttaag atttttttta attggacttc
     4921 attctataaa atattttaaa aaaggtctct cttccctgct aaataaaaaa atagaagttt
     4981 ctgttttaga tgccactgct ataggtattt ctatttttag aaaagatatc aatacggctg
     5041 gttcagttat gtttcttctt ggtatcggtg aactattaga agaatggact agaaaaaaat
     5101 ctatagacga cttggctcaa agtatgtcac taaacattga aaaagtatgg ttaagaaaag
     5161 gtgacactga aatcttaatt ccaatttcag agataaagga aggagattta gtaagtgtaa
     5221 ctatgggaaa tatgattcca ttggatggag ttatagtatc aggagaaaca atggtcaatc
     5281 aggcatcact tacaggtgaa tcccttgccg ttaacaaaaa agaaggctct tacatatatg
     5341 ctggaactgt aatagagcaa ggcaatattg ttatgtgcgt caaggaaaaa gctggtacta
     5401 ctagattcca gaaaatagta actatgattg aggaatctga aaaactaaaa tcttctgtag
     5461 agagtaaatt tgaacatcta gcagatacat tagttccata cagcttttta ggaagtatat
     5521 taacctatgc aattactaga aaccctataa aatcactctc tatattaatg gtagatttct
     5581 cttgtgcatt aaaactctct atccctattt cagtactatc agccatgaga gaatgtaaca
     5641 ataacaacat tactgtaaaa ggtggaaaat tccttgaagg tgttgcatgt gcagatacta
     5701 ttgtatttga taagacaggc acattaacaa aagctcaacc aactgtttca gatataatta
     5761 cattccaaaa ttataataag gaggatatgt taagacttgc agcttgctta gaagaacact
     5821 ttccacactc catagcaaat gcagtagttt acgaagctga aaaacaaggg cttagtcaca
     5881 aagaaatgca tacagaggta gaatatatta ttgctcatgg catttcaaca aaagttgatg
     5941 ataaaaaggt tgtaataggt agcaaacatt ttgtatttga agatgagaag tgtactatcc
     6001 cagacggtga ggaggataag tacaacaatc tatcagatga gtattcacac ctatttatgg
     6061 caatatcagg taaattatca gcagttattt gcataaatga ccctttacga aaagaagcaa
     6121 aatatgtaat ttcaaattta agagaatgcg gaataaaaaa gattgtgatg atgactggag
     6181 atagcgaaaa aacagctaaa tctatagcaa gtaaagttgg tgttgatgaa tattattcag
     6241 aagtcttacc agaagacaaa gccaattttg ttaaaagtga aaaactcaaa ggtcgcaaag
     6301 taattatgat tggtgatgga atcaatgatt ctcctgctat ttcagaatca gatgtcggaa
     6361 ttgcaatgag tgaaggtgct gaaatagcaa gagagatttc agatattacc atatcagcag
     6421 ataatttgaa taatttaatc gttttaaagc agattagtaa taagcttatg aaaagagttg
     6481 atttaagttc taagtttatt attggcttta atttaggtct gattttactt ggtgtaggtg
     6541 gatttgttag accaagtaca tctgcctttt tacacaacac atctactgtc ggaataagtt
     6601 taaacagtat gacaaattta ttggaaaaca ccaatactta taactaccat taatctccat
     6661 tacataaaac atatgatata aaaaatttat aattcatctt tttaaaagaa tatgtcttaa
     6721 aattagcttt tttctaatca aaattatata aagcatactt tacaaatttt aaactcaact
     6781 tatttctatt ttttacaaaa aaggagatga ttcaaatttt cattttgaaa catccccttt
     6841 tgtaaatttc tttaaaattt atatattaat tatattttca accaataatt gtattttcaa
     6901 ccaatctttc ttcatagcat tttaaatcat tttgctttag ataattaaat tcagactcta
     6961 cataaatacc acagcctacc aattcaattg tcaaattagg tatattttcc tttagtatac
     7021 tagtctgctc ataaataatt ctttccaata aatcaacttg taatatagaa aaatgcttca
     7081 taatctcccc atcactatct atatctttct tgatttcata ccaactcttt gacaaaattc
     7141 ccttcaaatc aatataccct agactcctca atatatctat actatcgctc catgcatact
     7201 tactaggttt atcaaagtat gattctagtt tcttcttctg ctcatttgta agtgaatcat
     7261 aagaaagctt cttattaaaa tgtgccttca aagaaatctt agccatagaa tatggacttc
     7321 taccagagtt taatcctgca tttttgaact tttcaattcc tttatcttct actgaagacc
     7381 atattgagtt tattgaatct gaatcattgt atttaatatc aagaccatgt gtaatattta
     7441 tatagttttg tggaaataca tattgataat agacatcttt tttatcatca tatagagaga
     7501 agtatccact atcatataaa tgaatatgca cctttacttt taaactatcc tctaaaatat
     7561 ttcgtctaag gttcgggata tttgcataca tggttacata ttttatggca tcaaagtttt
     7621 tatttaatgg aacttcaaaa ctaatttcat ctcctgtcaa aagctttttc acttcttctt
     7681 cattacaatc atatagagaa tatgtatttt caaatcccac acgtgatttc ccatctaaac
     7741 tgcctgttaa tgctaccttc aaaatatggt tatctgtttt ttgccattgg taagcatctt
     7801 ggtcaagaaa ctctctaatc tgtctatttt gctctttcgc ctgatttata acctcgtttt
     7861 catcttctgt aatccctaca tggcatctat ttaagatatt tactatattg cttccaaatg
     7921 ggaatgtcca tagttgaaaa gctgctgcct caacctgaca caaatatcta acctgattta
     7981 attcaatttg atggataagt tttttctgat attcattcat ctgattacca ctatctgaca
     8041 tttgataaat caattctccc attgcaagat tatctttttt cttatcaatc ttatcagtaa
     8101 tgataatttg agtttccatc atatcctgta cttttttaaa tattatagaa atctcctctg
     8161 agttttccat ttttaagctt ccaaacttcg tgcttaattc agttaaaact tccttcatct
     8221 ttaatttact tatctcattt tcaaaaatat cttgattttt aactgtacta tcgaattttt
     8281 ctacaaatgg tataacagat tctttcaaag ttttatcttt aaattccacc atttgagtat
     8341 tcaattcatc taatttctta atattatttt ctttatcttt aattgcctct ttaactacct
     8401 ctattttact ctcaaaacta gattttacat taagacaatt attaacacca ctaatcgcag
     8461 tatttataag agaacaagca gaacttccaa tactcaatgc atttttaatt ttagatgtct
     8521 tttgctgtct ttcaatagct tgtttacttt tctctagtgc agctaactta tctttttgct
     8581 gtttattatt gtaatttgcc tccaacatac ctatttcttt tttctggatt tttgtgtaaa
     8641 tttccttata ctcgctttca cttaacccct cttttgctct ttgaatatcg tcagctttgt
     8701 ctgcatagtt atcatcatct atagacttaa ctataatctc cttaatttgg tcaaatttag
     8761 ttcttctttc ttcatcaaca cctgccaaat tataagtcat tttatctaaa gcattttttc
     8821 tatcttcact tagctgttct ccaagtacaa atctcatacc atcagaatcc aatttaaaat
     8881 ctgaaaaatc aaccatcctg ttagtccatt ggtattcctc ttctttagct gaaagatttt
     8941 ccttcaaaga ttttgcactg tcaaatgccc ctagacaagc ttgaccaaca ccactaaatg
     9001 cagtcagtaa actcaatgcg ctttgtattc cagaaagaat taactgtgtt ttcatttgtt
     9061 cctcaagttt tgcctgtttc ttttttagtt cctctatgtc ttcttgttca tcttctttca
     9121 tctttataat ttcttgaatc aacaggttca tttttgcatt aacagaaagc attttattct
     9181 caagttcatt ttttaaaacc tctatttgtt gatttccaga ttcaatttga gttaggatac
     9241 tttccttata tgtattgaaa tatccttctt ttaactcatc tttctttcct tgttccaatt
     9301 ctcttaaggt cttatccaga tagtctgtca aagaacgaat atctgtaaca cgatttcctc
     9361 caatttcact ttcttcaatc atctgcacat aaaatgctgt cttctgctca agtgcaaata
     9421 aaatcatact ccattcgcta aaattctgat tttttcctac aaaagattct attctatcag
     9481 actgcatcaa tttatttata aggtattcat agatttcctt tgcctcttta taaaattctt
     9541 tctttatatt catgtcatcc atagaaagta ctgctttatt tttcttctca aaactatagt
     9601 acttctgaag tatttctcta tttaattgca tctctatttt ctcaactgca taaaaaattt
     9661 cataaatatg tgaaaattct aaaatatcag cttctaaaat tcctactgca cacaacagtc
     9721 taagatttct ataaccttta attccagaaa aaccaaatct ctcgaaaaat tcatagaaga
     9781 atgtatctat tgacaaagaa tactcctgct ttaacaattc cttttctttt agtgcatctc
     9841 cagagtgacc ggcttttccc tctgctccgg ctgaacctga atcttcacgt ttgctaattg
     9901 tccagtcctt atgttcttca taaagagtat ttaatttctc tccatcatct gctgcttgct
     9961 tctgatttaa agcatgatta aacacatatc tatcaaaata atagtagttt ctatcactat
    10021 tatccattgg aggagaggta cctatatatc ttattgtttc ttcatatata cctctaattc
    10081 caccaagacc tcctgcacca ccagctcctc cagagcctcc ttttcctgct aaaccatgat
    10141 ttccatcttt tttacttata gcacttttta ataaaggagc ttttccaagg agataaacct
    10201 gtccagactt gcttccaaga cctgcatttc caccattacc tcctgtgcct ccagttccac
    10261 cttgttttcc tttttctgct tttacaacat agtattttgt acctttaaca ttagcaaatt
    10321 cttttgactc ttttttagaa cctattttag catttgcccc agcttctcca gttatccctg
    10381 tatctccttt ttttccatct tgtccatttc caccacgtcc accatctacg taaagtttaa
    10441 gttctcctct tttttctatt tctttaaaag ataatatgat atcacctgaa gtacctgcat
    10501 tattgccatt tcttccattc attccgtcgt aaatagaact ttctccaacc aatttttctg
    10561 catccttacc agatacgttg attgaataag tcccttctgg tatatgtaat ttttctgtaa
    10621 gtagtacaat attcttacct gagaagactt ctttctccat attacagtca attttcaact
    10681 cacaatctcc atacatatat atagatgaca aaatattaag ttgataacca gatattattt
    10741 tagtcaaatc cgataaattc actttaggta taggaatata tatagaaagt acattttctt
    10801 tctcatatga ttttatatat gtacaacttt gaatcttctc tatcctatac tctgcatctt
    10861 caagcttttt ggcttcttct tccctatatt cttcttctgc tatccaatat ttgatatctt
    10921 ttaatgtatc ttctaaagta ttttttagca atgattttaa caactcactt agaccaacaa
    10981 tatgagtctc actacagtaa ctatttaact ctaaaagaag acgtgtttct tctaatatat
    11041 tcactttctg tacgccatca ccatatgaaa gttcttgtac aaactccata agctctttca
    11101 tattattagt cctactacat aaatctgtat acatcttatc taattgaatc tttttatctt
    11161 ttagactatt tatagaagat agaatggaaa tagaatcttc catacctttt ttaacacttt
    11221 ctatataagg aactaaaagt ttttctaggt ctttataggt tacatcaaca gctttttgta
    11281 tttctatttt acaagaagct gtaagcatca atcccaaatc tgttttttca aatgtttcag
    11341 gtagattttt catttcatcc aacaactttt ctggctgttt atctagtgga ttacataatt
    11401 taatagatac accatctgat aatgctacat ttaataagta cactaattcc ttacaaccgt
    11461 cgtaatcttt ctcttgacta tctaagtctt cttttgcttt ttccaatata tttcttattt
    11521 tttcttctgt tacattaccg attagtgttt taggtatttt attaataaga aagaagaaat
    11581 tttctttata ctttgcataa tcaccaagca tatctttcaa atttttgcct gtttctatca
    11641 ataatgtatg tctagagtcc agtagggatt gatagtctaa gataactacc atccctttca
    11701 cctttgaaga tgtggaaata gtttccctta caagcatagc accagcaatc atatactctg
    11761 ctccacggtt gtcaaaaaaa cctgggcaat cacataatga aaaatctcta tttgcaatat
    11821 ctacaacttc tggacataaa gtcttagaat atacaccatt tccaatttcg acagctgaat
    11881 cttttgcagt tatatatatt tgtccagtct cttcatccgt tttttcttcc atcacacagc
    11941 cttttaaata atttatacaa gtactctttc caacgcctga agcacctagg aataacaaaa
    12001 ttgacttttc ttttaagtca tattttctaa gctcgtctct tccttcttcc aaaaggttta
    12061 cgatttcact ataaagttta tttgccatac atccatccct ttctatattt cggaacaata
    12121 gccttgatat ttttctttaa taagattctc ttctaccttt gaaacagctg ttgataactt
    12181 agtatttgga gcattaaatc ctccattgtc tcctctatct ccatattcag cgtattctct
    12241 tgctggtcct gttttacctt cattccagct tccaccacta aattctatat gatatttaat
    12301 tatactatct aacttataat cccaacttgt aaaatatcct gtatagtata cagtcttatc
    12361 tataccactt ggagaaaatg aaagtgtatt atatccgtga tagccaccac ttcctccata
    12421 tccacctaaa cctggtctac catttggacc tgcttctcca tctttcactg ttatatcaca
    12481 atgattaatt attctatttt tttgttcctc tgaatctgaa atgaagtaaa tattaccttt
    12541 cttaccagca tttccacctc ttccagcatt tccaccagct ccaccttttt cacctttttt
    12601 gccacttgta cctttttcaa aatacccttt aaacatctgt ccgtggaaat aacttgtata
    12661 tcctgcatca gctccattac ttccagaagc tcctgtttca ccattttctc catctattcc
    12721 tttagaacca tttcctccat ttgcaatcag tgttagacga taatttctaa tttcttcttt
    12781 aatatataag taaatattac ctgcatctct accatcttca ccatttttcc catacataga
    12841 attatctaca agttctccgc tctttccact tacattaatt tttacattac tacctacatc
    12901 aagattgtta gaagcaagaa taatattttt ctctgatgca aagttcattc caaggttatc
    12961 atccatataa atagtatctt tagcaaagaa cataaaagta gaaacattgt catctacttt
    13021 tctatttttg aaatattcca atacactgct aattactaag tttggaatta atgctcttat
    13081 ttcaatacct ttcttatcat taatattaat tgtttttact ataaatggat ttaaaatgta
    13141 tttaccaata aattctctaa ttatctcatt accttcttct ccatatgcac ttaatcttgt
    13201 tatactgtct tctaactctt cattttgtgt aactgtaaca tttgtcaaaa ttgaattaaa
    13261 atcacttaca ctatatacat aatccttttt atttgcaact tccattaatt tttctctatt
    13321 tggtaatgta aatacctgtt tttgcacttc ataagaaact aaaacttttt ctaaattctt
    13381 tcttattata atgaagtttt gttccattat cttcttactt gccttttcta taataaattc
    13441 catatgtaca gaaggtaata aaatttcccc agttccatgt tctgtatatt tacttaaagc
    13501 atcaattata tctaagtttc cttttatctt attttgtaat ttcatgcaac tatcttgtaa
    13561 gaataatcca ctttgtttgg ctaatacgtt gataaaactc tctatagtaa gacttgttgt
    13621 actttccaac cagtttttaa atacttttac aacctcatca tattttgcta tttcttgaat
    13681 cattgttata cttccaataa tattgataaa atcttctgta tacgccttaa cataatcttc
    13741 taggctagat acgatattgt tttgaatttc ttttatcaac gtatctaaaa ctaatcttgc
    13801 atctgcacta attggatatt ggaatgctga tgtcttatct ttaacttcat ctaattctag
    13861 tacttgcttt aataagcctt ccctctcatc tgatgcaagt ggcttacaaa gatgaatatt
    13921 ttttccatta tcttttagca attcttcaaa taaccaagct ttttcctcta tattactgtc
    13981 taaattttcg cataattgtt catattttct ttttataaca ttatatattt gtttttctgt
    14041 tcttcctaag aaactttttg aaatgaaaaa agttatacta cccttaaaat tttctttatg
    14101 aagacacata tttaactgtt ggaacaggtc tagtactttt gtaagtctag aatctaatat
    14161 atctgcttct ggtatcaata caattactgc acatatagat gcagaatttt taaatacttc
    14221 acctaatgaa actgctgcac taatatcatg ggctactccc ctattgtcgc taaaacctgc
    14281 agtatcacat aattttgcat ccattccttc tattggtttt ctcatattta caatgttcgg
    14341 gtataaagtt tgagaaacag ctcctgaacc aatctctgcc acagggtcta agcaatcaat
    14401 atatgatata ccagtatctt catcttctac ttccatcatt acacatcctg caagatagtt
    14461 aattgcagta cttttgccac atcctgtccc accaagaatt agaattaaat tttgattttc
    14521 agccttattt attgctactt ttccttcatt taataaaagt gttatttctt ctaaaagttg
    14581 attgttattt tctggcattt attttccccc ttggttatat attttattta aataaagttt
    14641 aatcccttaa gtagattgca aagtttttag actatattta aatttgtttt ttatttttta
    14701 tttttaataa atttgcattt tcactaaata attattcttc tttgtttatt aaaataactg
    14761 tgttgtataa tataatcttt atcaacacag ttattttatt taatgcgctt attttattgt
    14821 attttatgta atacagttgt tttttatatt atatgtccat tatttttcta tggttattac
    14881 atatagattt ttaattatat ttgtaccatt aatttaaaca ttcctatact actgcttaag
    14941 ttttacacct ataccagctt gaatatttta tttttatttg cttaaatagt tcaactatac
    15001 tggtttaaat aggttatctt tatttgctta aatagttcaa ctatactggt taaataggtt
    15061 atctttattt gcttaaatag ttcaactata ctgatttaaa taggttatct ttatttgctt
    15121 aaataagttc aactatactg atttaaatag gtttccttta gtttaaataa ttcacctata
    15181 ctggtttaaa taggtttcct ttagtttaaa taattcacct atacctactt gaatagttca
    15241 cttttatttg cttaaattct ataccaatac tggcttaaac attatactac catgattgta
    15301 ttgtctatct tcaactacaa taaaaacagg ttctaaatct ttagtagatg ttatttttaa
    15361 ttctaaaaaa atattatcag ttggtaatat ttttacatca taattattta aattattatt
    15421 cgtgatacta ttaaatacat caccttgacg ttcaaaaaaa acattatcaa ctattacaaa
    15481 ataaacatct tcttttctac tattttcaac ctctatagta ttttgtttag ttatatttag
    15541 tctcatcttc cacctcctat taatattact taattatatt aatacttgta attgttgcat
    15601 tatgttcatc acaaggaaga ggtttaaaaa caactatctc tgctaaataa ttctgtggag
    15661 gatttgtaac tgaagtagca ttgcaaataa atttaaaatt tgttcctgct acaacttgag
    15721 tagaaacaat aagtggttca taaccaaccc cttctaacat tcctacagct tcattaaata
    15781 cttttaaatc ttcttcttcg acagctctga attttgacca tccaccaaca aaaagactca
    15841 tataaaaacc tcctttatat atatatttat ttatatatag tagtaccaat tttctcaata
    15901 ttcaatattt tctgtgtaac tggtcaatga aaatgcataa ctggataaaa atacttataa
    15961 aataacttaa ctttacatat aaatagctta ctttacatgt aataagatta ttctacatgt
    16021 aataagatta ttctacaata tgaaatgcat cttgttttga atatattcta aatacaataa
    16081 tggatatttt caattattat aattagaaaa tatccattac ttaacttgtt ttatttaaaa
    16141 tcacatagag actttattat tttttttatt gcatgaatag ctatttcagg tatcataagg
    16201 tgatataccc cctccttgaa accacaaaaa acatgacaaa ctttacgaat cttgtcttaa
    16261 aaaactacag gtacattcct tatttgtgga ttggagtagc cataacaagc aaattttaca
    16321 atttttatga tgacaaaaat caataaaatc gcttagtata taacacgaaa tactacttgt
    16381 tactattaag aatagttaga taggaagtat gcattataca aataaaggaa tcaataaaga
    16441 aagttaaaac atccctacaa attaaaaatc tgttacattt ttctatattt aaacgttatt
    16501 tacttacaat tggagaaata acaggttttc cttctcggtc aagtaaaggc gtaaatccgg
    16561 ctgcattgcc ataatagtgg aatacatagt tcacacctgt ttctttatcc acccaaatct
    16621 ccgttgcatt tattttccct tgtgaatata ctttttcaaa tctatctttt cccattttat
    16681 aatcctccat atttttgatt ggtctatgcc ttcttcactt aagtagaaaa aatacataac
    16741 ttattttttt aattctaata tgagcacgta aaaatgtcaa acagcttatt taatttcata
    16801 acttcatgtt actgttcgta accttgtctg tttacttaca ctgcattaca gcaccatttt
    16861 atcctttaca ttattgtatt gcacacagta aaaatgctta ctttatggga tttttcaact
    16921 aaaaaaagga ttttatctcc acaaaacatt tactatttgt tacaatatac ctaattttaa
    16981 tctcatatca acatttaatg aagatataac ctttttcaaa tattgtaaag actccttaaa
    17041 aatattagaa aaagattctg caaatctctc aacatctcct ttttttaaat acctaagtat
    17101 ctcaaaacat acatcaaaac gtgttttcaa aatttcatta tattcttcat gaaaaaatct
    17161 ctctaaatag attccaaata tcatatattg ttttaaatgc aaaaatgttt cctgtaatac
    17221 ataaatttgt gtataatcta ctatcttaca aagtaaaaca aaatctggat aaaccttaca
    17281 ctcttcacaa ttattttgta agtaccttaa atgagtttct attttatcta cagctatcaa
    17341 atccatttta tttcctagta aaagtactac atcctcaaga gtaatcgtaa caaactccat
    17401 agcatccaaa agcaaactca accttttagc tccttcttct gtatttatat aatcatcatc
    17461 atattcagaa aaaagcgtta catatgttcc cttgccatta attgttttag caattcccaa
    17521 ttcatttagc tcattatagg cacttctaac tgttggaagt gatacattat atctattaat
    17581 tatcgaagta attgatggta gacaatctcc tattttaata ttgccttcaa aaatttgaca
    17641 aattacatct gaaacaatta agtcatataa ataacatttt tccaacgtta cagaattaaa
    17701 actacttgta tctatacttt gtggagcacg attttctacc attttaagta tggattctct
    17761 acaagcttta tacatatatg ttaatagttt tttaaattca attagattcc catccaatcc
    17821 atataagtaa gtttttctta cctgctctat gtatttatta cgaaaaaagt ctatacaaca
    17881 attatccaag ttatccaagt tatcgaaatt ataggccaat tgtgaaataa tgacatcatg
    17941 ctgaataatc tcacaaaaat ggtgaatcag gaaattattt gttttactta ttagtttatt
    18001 tatatatttt agcctttgtt ctttaaagac taaataatta gaactatttt tttccataca
    18061 atcgataatc tcgtttaatt cttcaaagtc tttagatgta aatcttttaa tattgtacat
    18121 agcaatagaa ggaaatatta aactaaaaat cttatatatt tctgatattt gtaaaatctt
    18181 ctcatataat aagtcagatt ctattgattg tttactcgta ctctggatta aaactggtct
    18241 agaaccagct tttgtctcta taaagccctt ttctgagagc atttttatta cagtttttat
    18301 agtatttttt gataccatat attcttctga catgcttttt atagaatcaa gcctatctcc
    18361 aatagtaatt ttaccagtat aaatttgttg aattatatgc tcaaaaataa ttaaatattg
    18421 tggttttctc ttcatatttt tcctcttcga taaattagat ttattgtttt ttgtaaggta
    18481 tatttacttt tatttaatag ggcaaaatag ttgcttattt tttcctcata atctataatt
    18541 aatataaacc atttatatat atggtctaag ttttataata ctgtaatgca gtaaaatagc
    18601 atgttgtagc tatactacag caaattaaca taccattgta gtatattaat tggaataatt
    18661 ttaagtactt caaaattcca gcaaaacata tatgtgtttt tgatattatg tatattcgtt
    18721 aatagaatag ctatacttgt tttacataat aaattatatg atacttgcta tatgtaatca
    18781 ctatatttaa tacacataac tattatactt gctatatgta attactatac tttatacaca
    18841 tagttatcat atatgctata tgtaattact atactttata cacatagtta tcatatatac
    18901 tatatataat tactatactt ggacacatag ttatcataca tgctatatgt aattactaca
    18961 cttggacaca taactactat attt
//
LOCUS       DAMJWC010000071        18900 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMJWC010000071 DAMJWC010000000
VERSION     DAMJWC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.071"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(93..2063)
                     /gene="ftsH"
                     /locus_tag="PC503_002955"
     CDS             complement(93..2063)
                     /gene="ftsH"
                     /locus_tag="PC503_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2528921.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIIVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2097..3485)
                     /gene="tilS"
                     /locus_tag="PC503_002956"
     CDS             complement(2097..3485)
                     /gene="tilS"
                     /locus_tag="PC503_002956"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF2528922.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDGEGIICVGDYKISENYKIDES
                     TKEVLKINFNKL"
     gene            complement(3668..4096)
                     /locus_tag="PC503_002957"
     CDS             complement(3668..4096)
                     /locus_tag="PC503_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF2528923.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4113..4919)
                     /locus_tag="PC503_002958"
     CDS             complement(4113..4919)
                     /locus_tag="PC503_002958"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF2528924.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(5121..5606)
                     /locus_tag="PC503_002959"
     CDS             complement(5121..5606)
                     /locus_tag="PC503_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF2528925.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5657..6316)
                     /gene="spoIIR"
                     /locus_tag="PC503_002960"
     CDS             complement(5657..6316)
                     /gene="spoIIR"
                     /locus_tag="PC503_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF2528926.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6461..7141)
                     /locus_tag="PC503_002961"
     CDS             complement(6461..7141)
                     /locus_tag="PC503_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2528927.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7125..8015)
                     /locus_tag="PC503_002962"
     CDS             complement(7125..8015)
                     /locus_tag="PC503_002962"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF2528928.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8133..9683)
                     /locus_tag="PC503_002963"
     CDS             complement(8133..9683)
                     /locus_tag="PC503_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2528929.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVECIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9777..10043)
                     /locus_tag="PC503_002964"
     CDS             complement(9777..10043)
                     /locus_tag="PC503_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF2528930.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10191..11051)
                     /gene="yabG"
                     /locus_tag="PC503_002965"
     CDS             complement(10191..11051)
                     /gene="yabG"
                     /locus_tag="PC503_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF2528931.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11135..12073)
                     /locus_tag="PC503_002966"
     CDS             complement(11135..12073)
                     /locus_tag="PC503_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF2528932.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12183..12344)
                     /locus_tag="PC503_002967"
     CDS             complement(12183..12344)
                     /locus_tag="PC503_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528933.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12354..12851)
                     /locus_tag="PC503_002968"
     CDS             complement(12354..12851)
                     /locus_tag="PC503_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2528934.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(12966..13676)
                     /locus_tag="PC503_002969"
     CDS             complement(12966..13676)
                     /locus_tag="PC503_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF2528935.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13852..14382)
                     /locus_tag="PC503_002970"
     CDS             complement(13852..14382)
                     /locus_tag="PC503_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528936.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14399..14629)
                     /locus_tag="PC503_002971"
     CDS             complement(14399..14629)
                     /locus_tag="PC503_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528937.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14644..16038)
                     /locus_tag="PC503_002972"
     CDS             complement(14644..16038)
                     /locus_tag="PC503_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2528938.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16164..17417)
                     /locus_tag="PC503_002973"
     CDS             complement(16164..17417)
                     /locus_tag="PC503_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2528939.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTIPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17468..18622)
                     /locus_tag="PC503_002974"
     CDS             complement(17468..18622)
                     /locus_tag="PC503_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2528940.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGISGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
BASE COUNT         5837 a         3613 c         1859 g         7591 t
ORIGIN      
        1 atataatttg cttattaatt taatattata ctttcagttt tagtatttaa tccacatcag
       61 ataataatct taaaatgacc aaggtcttaa aactatttat ctttatcaga tttatcttct
      121 aaatttttat ttatatcaat aacattgttt ctttcttctt catctttttc taattttata
      181 gttaattgtt cttcaacttc tttagaagaa ttttcctctg taactgcatt ttcaatttca
      241 ttcagaggta actctttatt aaatgctttt acaaattgtt ctgcatctaa agtttcatat
      301 ataagtaaag cttgtgctac atactctaat ctatccatat tttcttgtaa tatacttctt
      361 gtcttatcat atgcaccatc aactatacgc tttgtttctt ggtctatctc aaaagcaact
      421 tcttcagaat aatttctctt acttgaaaaa ctattaccta ggaatacttc atcatcactg
      481 tcaaatgaca ttggaccaag tttagaactc attccatact ttgttaccat acttcttgca
      541 gtagctgtaa ctctttctaa gtcatttgaa gcacctgtag atacatcctt aagtactagc
      601 tcttctgcta ctctaccacc aagtaaaact ataatatttt ctttcatttc attttttgta
      661 gcatagaact tatcttcaac aggaagttgc attgtaaacc ctccagctct tcctcttgga
      721 actattgtaa cttgatgaac aggacttact tcttcaagta catgggcaca aactgcatgc
      781 cctccttcat ggtatgctgt aagtcttctt tctttctcac ttattacttt cgatttttta
      841 gccacacctg ctataacctt tgttatagct tcttctatag tttccatctt aattttcttt
      901 tctctttttc tagctgttaa tattgcagcc tcattcatta agttctctat atcagcagga
      961 gtaaatcctg gtgttcttct agccaagaca tccattttta catcatcact taatggttta
     1021 tttcttgagt gaactttaaa tatagcctct ctacctttta catctggtgt accaacaaca
     1081 acttgtctgt caaatcttcc tggtctaagt aaagctgggt caagtatatc tggtctattt
     1141 gtagctgcca tgattattat accttgattt accccaaatc catccatttc aactagaagt
     1201 tgattaagag tttgctctct ttcatcatga cctccaccaa gacctgcacc tctttttcta
     1261 ccaactgcat caatttcatc tatgaatatg atagctggag cacttttctt agcctgttca
     1321 aataaatctc ttactcttga agcaccaacc ccaacaaaca tctcaacgaa atcagaacca
     1381 cttatactga aaaagggaac tcctgcttct cctgcaactg ctcttgatag atatgtttta
     1441 ccagttccag gaggtcctac cataagcatt ccttttggta ttcttgcacc caattcaata
     1501 tatttcttag gattctttaa gaaatctact acctcctgca aatcttcttt ttcctcatct
     1561 agtccagcta catctttaaa tgtaactcta gttttttcat catctttatg aaccttagct
     1621 tttgatttgc caaaactcat aacctttccg cctccacctt gagactgatt cataaacacg
     1681 aaccaaataa tcaccatgaa gaatattaac agtaatgtag gcaacatttc gacaaaccaa
     1741 ggtgtagatg gcttagcttc accaccaaaa gttagtttcc cagccttagc ttggtctaac
     1801 acctcatctg caagtttatt tcccatcact tctgttggaa catatgactt aaactttgta
     1861 tttgtatctt ttatagtacc ttctacagaa gtttgattta caaagtataa tcttgatata
     1921 ttctcatctg ttaattctct atatacttca gagaatttta aatcttttat tttttctgta
     1981 ggcttacctg agaattgaac tatacctact ataattataa aaacaagtag ataaaaacct
     2041 gcccctttta gcaacttatt caatatagaa gccctccttt catacattgc tttgccctat
     2101 aatttgttaa aattaatttt taatacttct tttgtgcttt catcaatttt ataattttca
     2161 ctgattttat aatctccaac acatattatt ccttcaccat ctgtgattat aggaatttta
     2221 catctttctt ctcttgggat ttttaaatct atgaataaat ctttcacttt tttacttccc
     2281 atagcaagct ttatcttatc accttgcctt ctgcttctta ttactatacc cccttttacc
     2341 ttattaaaat caaacccttt agatgaattg tctaatttca tactcttata cctatctatg
     2401 ctcattactt gggtctcaat aatttgtttt aattctttta ttttaataaa cccattacta
     2461 ggtacattgt aataaaattc aatttcctca ttaacaattt cctcattcgt taatattata
     2521 ctgtcttttt ttctataaac aaatatattt cttggaagag ttaacatttt atttactttt
     2581 gaattatctt ctaaagacat tatatcttct atatgtcttt ggtcaacaaa attagtatct
     2641 cctagtatat gttttatgga atttctaaga actctaactt tgatagcatc atgtaagcaa
     2701 acaaaatcgt ctaaatttat ctctacaaag cctttttctt ttatatttga aacttctcta
     2761 aatttagctt ctgcctcttt ctcaatataa tcgttatcac tttttaaact attgctcatc
     2821 ctcactatag attctattac atttgaatta aaattatcct tcatatatgg taaaaggtct
     2881 aaccttatct tatttctagt gtatatattt tctaaatttg ttttatctat cctcggattt
     2941 aaattataag cttcacaata ctcctctatc tcatttcttt ccacgtctaa tatgggtcta
     3001 attatgcaat tatctctaat ataatcaatt ccctttaagc cttttaaacc tgttcctctc
     3061 atgatacgca tcataaccgt ttcggcttgg tcattgagat tatgacctat tgctatttta
     3121 ttggctttaa tcttatcctt aatttcataa aacatttcat atcttagctt ccttgctcct
     3181 tcttctaatg ataatccctc attttcacaa tattttggta cattaataga ctttacaaag
     3241 aatataattc ccatatcctc acaaagttta gatacatata atgcatcttt ttgagcttct
     3301 atccctctta tttgatggtt taaatgtgct gcatatattt ctatattaaa atcttttttt
     3361 aatctattta gtacatgcaa taaacaaact gaatcaggtc ctccagaaag acctaaaact
     3421 attttatcgc ctttttgtat taaattatgt ttatttatag tacttagtac cttatcaaat
     3481 atcatattta tccctcttac acttagtttt attcactttt aagtatactt tctataaaaa
     3541 aacgctaaac ccttgtatca attttaagaa attaaagttt aatataaata taataatacc
     3601 aaataaatta aataaaaggt agttttttca ctacctttat aaaatttctg gaaaatagcc
     3661 atagttatta tttagtacct atgtatatat ctattttatt cctacctaaa aataaatctt
     3721 gtacctttat attatagtct attttcaatt ttatgtgttc cccttcttgt atatttatat
     3781 ctaattctct tgtatcaata tcaattaata aagtaccttg tggggtcaca tactttgtag
     3841 tactactttc tccacattta aacagcattg ttgagttaat agcaccaaac tttttgatac
     3901 taacttgatt tttaagtatc tttatagtat tagttatttc tatatcttct tctttttcct
     3961 tgtaaataac atatattcca tcatttttat aaaaaatttt accaaaggca gtcatctcta
     4021 tggtgtccat atttcctttt tcatcatatt gtctagtatt tatacttatt tttacactca
     4081 acgatttttc ctccatagat tcttcatata aactagtatt tttgtatttc tactttttga
     4141 atcttatcaa tttttttctt taagaactct cttgctatat ctgaaaattt ttcaggtata
     4201 tctgatacat aatattgata agttccatga atttctgtat tgtttataat attttgcacc
     4261 tctaaaatct tttttaaatc ctttgcagtc tctttagctg gattaacaag ttttatatgc
     4321 tctccaactt cttcacctat tgttctcttt aaaataggat aatgagtaca tcctaacact
     4381 aaagaatcta tatttttttc tttcaattct tgtaaatata tctttgctgt cagtttagcc
     4441 acttctgtat ttgcccatcc ttcttcaaca ataggcacaa ataaaggaca tgctttatta
     4501 acaatttcta tactctcatc tattttagat atttccaagt tgtatgcttt tgaacttata
     4561 gttccttcag ttcctattat tcctacaatt ttgttttttg tagaacttac agctgttcta
     4621 gctcctgctt ctataactcc aattatcggt atatcatatt tttcttgagc ttcttttaag
     4681 cttcttgcag tagcagtgtt acatgctata actatagctt ttacaccttt tgtttttaaa
     4741 aagtttatag cttgaaaagt atatttaatt atagtttctt tggatcttga accatatggt
     4801 attctggcag tatctccaaa gtatattata tcctcatttg gtaatatctt cattatctct
     4861 tttagaactg ttaatccacc taatcccgaa tcaaaaactc ctattggttt attgttcatc
     4921 tttatacaac acctacttta catttttgtg tttaacaaca acttatttat cgctaaaatt
     4981 tatatttata ttcataatta atatattatt acctaaatga ttattatagt ttattttaca
     5041 caaaaaataa aggagctatc ttaaattaga aaataatttc tacaaaaaga caactccttt
     5101 cactacttaa aaatttaaat ttattttgca aacacatgat ttcctattct catataagga
     5161 ttcaatctat ttatccattt gcaagtggct atttctggat tccaaaaata tactgcttta
     5221 ttagttgggt cagttccata aagagcttcc tgagctgctt tacgtgctga gtctgttggt
     5281 gccatcttta ttgaaccatc aagcacaact gagaaagcat ttttttgata tatgacttct
     5341 tctattgtgt ctggaaatct agggtccaat actctattta ttactacagc tgctacagca
     5401 acctgtccct catagctttc tcctctagct tctcctgcaa ccaacttaga taataacatc
     5461 aagtcattat cagataaatt tattacttct ttctttgcta tatttttttc ttgtttgttt
     5521 actttcttaa tattttctgt tggttcatat gcaaatacct ctttaatagg cataaatata
     5581 aaagtcaaag ctaatagtgt agccatcagt ttactccacc tgtccatgat taaaaccact
     5641 ccttacattc ttatttttaa aattttttct ctaaatcctt gactacttca agtactttaa
     5701 acttaatttt tactctactt gttttttttg gtgtatcttg ttttattaac ttatattctt
     5761 tatcagttaa aacttccttc aacttatcat ctgtagattt atctatcact ccattagatt
     5821 catcaacaaa acatagtgga gggaacataa cacaccacca gttttttcct tcacctttcc
     5881 caataataat ctttaatgct ttatattcac cagctggaag aactatatta gaatattgtt
     5941 tagtagggaa attgctatat tgtataccta cctttacact gtaattatat ccatttttaa
     6001 gaataatatt tttacttatt tcttccagac tactatattc cttttttata atagcttcac
     6061 tttcttttat actttttgaa ttttgaagct ttggctgtaa atattttatt acttcatctc
     6121 taacttttag tttaagttct tggtcttcat ctgtattgct gtttgctata acatgaaatc
     6181 ttattaattt atctttataa tcttttgata tattgtctac tttttttacc tcaccattta
     6241 ttactattgt cattattgat atgactgata taagacttaa tattaatagt cccaatctaa
     6301 tcttaatttt tctcattgaa aattccccct caagataaat ttatatcatc aattatgtcc
     6361 aattaaattt aatttattca taatattttt taatactaat aaaaaaagct atcttaaaat
     6421 gattacaatc attttaaaat agctttttaa accttatatt ttataagtct ttactaatca
     6481 tagccttatc tatcataaac tgctctgctt tttctatatg ctctgtagca tacttcttgg
     6541 atagctcact atcaccttta attatagcat caagtaaata tttatgctct tcaacaatat
     6601 tatgtgatgt atcataagca gacatatagg taactctaaa tctatatact tgttcccaca
     6661 atgagtttat taattggatt aattttttat tattagttgc tttaaatata cattcatgaa
     6721 attctacatc aagttttaat aacgcatcta catcggattc caaagtgctt tttttaaatt
     6781 cttctgatat atctttaagc tttttaatat cttcatcact aattctttca gcggcaagat
     6841 atgctgctaa gccttctagg cttgctctta cttctaatac atccataata tcctttaatg
     6901 acatatttgc cacatacgca ccttttctag gcaacataac gactaaacct tctaattcaa
     6961 gctttcttat tgcctctctc actggagtcc tacttactcc taattgttct gctagttgca
     7021 cttccattag cctttgacca ggctttaatt ttccttctaa gattgcttct cttaaattct
     7081 caaagactac atctcttaat ggcttgtaat tatccaagtt cagtttagtt aaattctcca
     7141 caaatttcaa cccctttttg actgctatta acaacataca cctgtttata tttttttaat
     7201 aattcttttt ttccaattag agcatcttct ttatttttaa atagtccaaa aactgtagga
     7261 ccacttccac tcatcataga acctaaagca ttatttttca tcattacttg ttttatatca
     7321 cttatttctt tgtgtttacc tatagtaaca ttttcaagaa tatttaccat gctttctgat
     7381 acagctttta tatcttcaga ttttaaacac tctatcaaat atttattatt tggtcttttt
     7441 ttaatattat tcaaatctaa tccttgataa acttctttag tagaaacgaa taagtctggt
     7501 ttgcatatca atatatttgt atcacatggt aaacctttga tatttgttag cttttctcca
     7561 ataccttgag ctaaggcagg tcttcctgat atacaaaaag gaacatctgc gcccaaatta
     7621 agtcctattt cttttaattc atcttcagat aatctaagtt cccataggtg atttaaacct
     7681 actaatactg cggctgcatt agaacttcct ccagccatcc ctgctgctac aggaatattt
     7741 ttttctatga atatttctac accttttttt atataaaatt tatttttaag tattttggca
     7801 gctttataaa caatattatc ttcatctaaa ggaatatcta aactagtgct ttttaccttt
     7861 atttcatctt cgtctaattc ttttatcttt actatatcgt ataaatctat cgtttgcatt
     7921 atcatttcaa caaaatgata accgtcttgc ctttttccca agacatcaat ggataaattt
     7981 atttttgctc tactctttag tcttataaaa tccattctat cctccttgtt taaagaataa
     8041 tgcatcacta acaataatat tatactacaa aaaataaaat aatagggtat tataataccc
     8101 tattatactt aattacttta aattttttaa tattaatcta ctaatacgac ttttttttct
     8161 aaaataagac acttcccagg cttaattggt tcatcaagtt ttatatcatt aagttctgca
     8221 atttcatttt ctgttgtatt gtattttttt gctatattcc agaaagtatc tccttctttg
     8281 catatatata cgattatgct aggagcttta gataaatcat atacaccttg gtcttctccc
     8341 ttgataataa aattttctgc tttcttatct aatgcttcag taaatctctt aattttgata
     8401 atcaagtcta tctggtccct attcaaatca acttcgactt tatcaataca tgctgtatta
     8461 aacacagatg ctgtatcagt tagattatcc atttctatat catgttcaaa tggaatttcc
     8521 tcactaattt tataaaccaa ttttaaacct tcaactggga caaataaaat ttcaactttt
     8581 atgattcctt gtataatgct tttatttcct tcaatataac tattttctat agacatggtt
     8641 ggacaaacgc ttacaatatc ttttatttgt atatcatcat tatcatttct tatgccttct
     8701 ctaaccataa atgtttcttc actacgtctt aaagtcttat ttaattgaat aggtttgtgg
     8761 tcaaatttta ttatcttttg aggcgaatat gcatcttgta atacttctct tgtaacttca
     8821 tctgtaactt ttaccttaca acaagccata caatctattt ctaaaagacc tgtgttgctt
     8881 tcactatttt gcttgaaaat atgattaaaa tctgacatag acaacaatac ttcttcagtc
     8941 ataccatcac taactccagg gacttctaca aattgagtaa actcaatacc tactctatcc
     9001 aactctacaa gttcaccctc atatgtacaa gctaacggat ttatttctaa tactccacca
     9061 ataataactt tattgtcagt cactctactt tcttttactt taacacatgg atttaaactt
     9121 attatagatt gaatttcctc tgtgtttatt gttatagtat ctcttataga actttctgct
     9181 ttttctattc caactatatc ttgaaaacaa atttcctttc tgtgcttttg tatgcattcc
     9241 acttgcgcca catcttttac aatgtctaac ctttgctttt caaacaaact tccccttata
     9301 ttcataagag ctcctacttt aatctttctc tcattcatta tagtacaatc catatgctct
     9361 acttctgaaa ataacatgta ttccatatct tgaataacat tgtctttttc tattacttcg
     9421 tttatatcta cttttccgtc tacattagaa atagtatttt tatcatctgc aatatagatt
     9481 acattataat taaaactacc tctgcaaagt atcttcccat ctgccatttc aattttttta
     9541 agtgatatgt atccttctgt ttttacaatt tcatatacat ctaatttttt gtctggcaca
     9601 actgcctccg cttcaatgaa tgtttgaaat tttccaaagt ctattctatt gtcaacttta
     9661 attacatctt taattaattc catagtctac ctccttaagt attataaaaa tatcacacta
     9721 tatttatatt taaggagcaa aaaaaaaatt acacctattt ttaaataggt ataattttaa
     9781 cttatttgta atttatcttg atctctaaaa acttgcaact ttacattaga tgttaataaa
     9841 tctgagtaac tataagatac tctaggatat ccattacttt catcatctaa ctttataaca
     9901 aacacgcttg gataaacttt ttctagtata ccctcttttg taataatctg ctttcttcct
     9961 ttattagctt tcaacaatat tttctttcct atatgtctct ctaagcttac tcttatctta
    10021 tctagagttt gaacagtagc cacaatatca ccttctttaa cgtttatatg tttacataat
    10081 atcacatata aacatttttg tcaaatgttt aaactaatta ttttatatat tttttgcaaa
    10141 aatgtcaata ctatttttga agatatacag tataattatg ttaatttttg ctaatgtaat
    10201 attgtttttg gcattgccca tctaaatttt cctcttgttt cagaaccacc aattccctta
    10261 acacctgtaa tagtctgctc tataacctca tcaataggaa ctactacatc aattcttgaa
    10321 caagcaattt tctccactat aaaaacaggg tctaatgcat gtatcattat tcttccaggc
    10381 gaacttgcat agtttgctcc tgcacttatt attttttcat aatttgattg gcatgctcct
    10441 gcgaatatga caagattatc caaatttggt tgccatttac gtgcttcttt tactgtttta
    10501 acaaaatttg aagagtttct atagttactc atatcttcta tatctcctct ttttattgtc
    10561 attgcatcat gacctgttat tactagtata tccggattat atttttctag tagtgctctt
    10621 acttctttat actgattttg ctctgaaaca gctacaccta ctgcaggtat tccaagttga
    10681 gcatatacat ccaagcaaat ttttaaatat tctttatctc catctatctg tagtactttt
    10741 ccaggcattc catatgtgtt aggatttaat tgaagttttg gaactgctct agtcattctt
    10801 ttttgtcttt ctttagcttt tcttactgac ttatataata aattttctac atttttatct
    10861 attaatatat cttttatatc aggtgctttt actaattcta ggtcatcaat ataagcatct
    10921 gctattactc taaatgcaat tccctttagt atagctattt tctcattatt ttcatctaca
    10981 ccaaaagaga ctattttaaa tactatatct ttgttatgtg actttctagc tacaatgtct
    11041 cctaccttca tagttaaacc tccaataaat ttttatctta gtttatacta tgttcgatat
    11101 aaaactttgt ttcctaatgt caaaaaaaca tttcttataa tacttctttt atcactctta
    11161 aagcattttt atagtatatc ttttctatat catcttcact aaacccttct ttttttagag
    11221 gttcatacag tttacccatc tgagatatat cttcaatctc aacttttgaa tctattccat
    11281 caaaatctga ccctagagat acaacatcta ttcctccaac atttacaata tgttttatgt
    11341 gtctaaccat atcttcaagt ttactttcac ttttatcact taaaaataag tggaagaagt
    11401 ttatacctgt aactccacct ttatttgcta atactttaat catatcatca gttaaatttc
    11461 tagaatgatt catcattgct cttgaattag aatgtgtagc aattattggt ttagaagaaa
    11521 tctttgcaat ttcataaaat ccaccatctg aaatatgaga aacatcaacc aacattccca
    11581 attcattcat cttatgtacc acttctcttc caaaatcagt aagccctttt tctctatatt
    11641 ctactttatt atgaggaaag ctcaattcat tcacatgatt ccaacttatt gtcatcattc
    11701 taacccctaa gtcgtaaaat ttctttaaat tttctaattt accttcaagt actgcacctt
    11761 cctcaataga taaaagagct gtaagtttac cttctgattg gtttttcata atttcttcat
    11821 agttagtagc taaagctatt tcatcactat tttttttcat ttcctcatga aatttatttg
    11881 ccatactcat gcaataatca aaaggatgtt ttacttcttc agtatcaaca aaaagagcaa
    11941 atgtttgagc taatgaatcc ccctttttca atctgtctat atcaacagaa tatttattag
    12001 acttaagttc acttgtttct acattttcca ttaattttgc tatagtatca caatgtaaat
    12061 caagaaattt catatttata ccccctgtat attttatatt tatatctaaa aatagaaata
    12121 gttgtcctta tagacaacta ttgacaacta ttttttaata ttctttttaa tattacttaa
    12181 tcttattctt cttttaagtt aggtattact tttttaactt cttcaatttg atgccatgtt
    12241 ttatctatat tattttcact aatatatttt tttaaatcag ttaaagatgt aaaatcttta
    12301 actgataaat tgtcatcatc atctgcaaat cttaaaataa acatgagact cccttacttt
    12361 ccacaacatt tcttatattt ttttccgctt ccacatgggc atgaatcatt tcttcctatt
    12421 tttgcttctt taactattgt tttagacttc ttataagcct ttattatttc ttttctttgg
    12481 tctgctggta gtatatcttc ccaaccttgt aaattatata gccaatgagc ctcaacagtt
    12541 accatattgt tatataattt ttcccaatct atttttatag aaacttcttt atcagcttct
    12601 acttcttcta aaactatatc ttcttttaag ctttcactta ttccatctat gaatcccatg
    12661 aaaaattcat tagtagttcc aaatttttca gccaattcac ttactttacc ttcaacaaca
    12721 tccattttat tatttaatat ttcattgtat attccagctt caactttcaa atattcttcc
    12781 cagaatttta cttctgcttc ttgactttca tgattatcac ttaaatttct ccattcagta
    12841 tataaactca tactttttcc tcctaagtat acctatattt ttatagtttt tatagtataa
    12901 aatcttttag ttagattgga agtttcttct ttttgattat accatattct atttaaagtt
    12961 aactcttata ttatatcata attaaacaat tcttttaata cttttatagc atactcttgg
    13021 tttataaaat aagggcttgt cgcaattgtt attactttgg cttttttaat taagtttttt
    13081 atcttgtaaa atttgagttc aaatggtata tagtccatat cacttgaaaa tatatccaaa
    13141 tctatatcaa gaacaaactc tgattctact tctaaatcaa atccatatag actatctatt
    13201 attattaatt ctgaaaatat gttatatttt aaagcaggtt ttataaaact tcccacattt
    13261 aaaacttcat ttgtatatct aaatacatct tttagattat ttacatctac atcatagttc
    13321 tcaggttctc tagtatcctt atgttggtct acatgcacta acttgcatcc ttttgtaaac
    13381 tcacccttta acaaagattt tgcccaaaaa taaaatgcat ggttatgatt gtcaaacaca
    13441 tatatctttt tatttcccag gacatattcg accatattct ccaatccttt tgcttttatt
    13501 tccttatttt catctacttc attaaatact acctcattgc ctaaccttac atcatttaat
    13561 gtaccattta ttagttttgg aacgtatatg ctcttatttt ctcttttatc atatgaaaat
    13621 acattatttc ctactggttt ttctatataa aatccactat attcataatt ttccataaaa
    13681 ctttatttcc tccattgtta tataaatata taagttataa ttttaaaaat taaaatgcac
    13741 ttattgtaaa tcatatcatc tattatagaa aacatcttat ataactaaat ataatatctt
    13801 ctctcaatat gtattataca ataagtgcaa aatatattta tataaaatat actacattcc
    13861 tataacaaaa ccatcagctt caattggaag gtaactaact cttctattca actccacctt
    13921 tccaaaaaat actacccaat atggtctaaa aatactttca attttaacta tttcaatctc
    13981 tgggattcct cccataaacc tatgagttaa tctcatagcc attttatttg cctttgcttt
    14041 tactcttcgt tcgtccttat cactatactg cacaatatta caatccacat tttttacaac
    14101 ttcatatgta ggaaaatctt gtactatact accagaacct gtagaaccat tcactaaaat
    14161 ttttaattca tttatatcat tagaatatct cctattcttg aaaatggatt tcgttttgtg
    14221 aattttaagt gtgataattt taaactctat ataatgaagt ctaacttcat gagcatattt
    14281 gttctttaat attagcttac taaataaaga attttttcca cttttagcta tctctatagc
    14341 ttcttctttt gtaattctta taggtaacgc tcttatatcc ataaaatcat tctctttctt
    14401 atttttttct tgtcattttt aaaactctat atatataatc aaaaaatatt acaattacaa
    14461 ctgccataac tccatatgga attatttttc caactataat atcatttcta gtcaatatac
    14521 cataaaatat aaatcctgtt attaaaaagt acaataatac tagaaaaccg tctattccaa
    14581 gccattttat ttctaaatct ttttttacct tagacactaa tttagacata gcagtttctc
    14641 cttttataga ttattttgtg tatttaaatt ttcaccgatt ctattaccaa tcatccatgc
    14701 aataaatgaa aaaggtatag ctatcacaag aggctctaac tcaaagctct gaactggaaa
    14761 tattttaaaa taaccaaaag tcactccacc aacaatcatt cctaaaatac cacccataga
    14821 tgttcttctt ccatttccaa gaagcccacc tactataggt acaaatgccg aacccatcca
    14881 aatacttcct acaaatatac atgcatcata tacattttca aatctaaatg ctacgctaag
    14941 ccccataact gctgctaaac atacacctat tctagtaaac tttactaatt gtttctgaga
    15001 taactctttt tttgtaattc ttccatatat atcatttgct aatgtagccc cagctgctag
    15061 ataatagcta tccaatgttg atattataga acctaaaatt cctattataa atattactct
    15121 tattccttgt ggtaatgtat ctaaaactaa agttatatat ccagcagctg gagccatttc
    15181 tggataagta gctcttacta taagtcctgt catagttaac accatgtcaa aacatatcca
    15241 tagtgaaaaa caggttaata aggctcttct tccaacctta ggagaatctg ctgctgaaaa
    15301 tctttgataa aaagttgggt ctgaataagc tccaaaagaa tatacaatta acatcaatgc
    15361 tttcatagct gacatacctt ttgtagggtg cataagctgt ggtgcatctt tgagtgcttc
    15421 tgtaagacct tgaaaccctc ctatttgttc aaattgacct ggcataacca tagttaaacc
    15481 aaataccata caaaaaaaca ataccatatc tgtaatggca actcccataa gcccaccaag
    15541 tactgtaagt acaacgacta ctcctaccat tattaatcct attaattctt tatctatttt
    15601 ccatgctacg ttacctatag ttcccatagc agttatttct ccaagttgtg cacaatatat
    15661 aaacatcaaa attgccccaa ttatagcaac atgcttgcca taaaaacttt ccagtaaatc
    15721 aggaactgtt atattggttc ttatatgaat ccttggacca acccacaatg ctaaaggcat
    15781 tctcccaata tgtgcagcta ttgaccaaac tgcccatgca gatattccat atatagccgc
    15841 atactctaca ctacctactg taccaactcc tccataccat gatgcaacca aagttcctac
    15901 tattaaggac catggtaaac ttcgatttcc taggtaataa ctttccatat cttttacatt
    15961 tctagaaaaa taataaccta ttcctaataa tataaatgca aatataacta taatcccatt
    16021 ttcccaaaat gttaacatat ctaatctcca cattcttata ttttaatttt taactttaat
    16081 atctaaatat gaacaactct acccatttcc ataaaaatag gtagagttat ataataatta
    16141 taagtattta agtaatcttg ttattaagca attttattgt ttaaaccttt attttctctt
    16201 ttatttattt tatttaaagc ataagtagca aatatcccta taactgcaca tactacagat
    16261 aaaataaata tatatgtata tcctgtttgt ccatatttat ctaaccaatt acctgcaata
    16321 gtgtaataaa acgcatctgg agaaaatcct ataaatgaag caaatccaac tactgctcct
    16381 gtagtttcta aagatatatt agactctgaa acagatgcaa agtatatacc tctaaatcca
    16441 aataaaatta cacttagtat tatcatgttt attacagcta tccatataaa tcctgtactc
    16501 ttaggaataa ccaagtaagc agctgtactt actgtcatta atataaatcc tacaaacatt
    16561 actcttatag atgaaccaac tttatctgtt ataacaccag caactggaga tgctcccatt
    16621 tttataacat aagttcttat tattgataaa gcagaaacta gagtcattgg cattacataa
    16681 acttctgata agtatggact taaataagtt aaacttgaga atactaaata agttgaaaat
    16741 attataagac caattaacca agcctttggt attgtaacta cttttaacaa tgacttaata
    16801 cttaatcctt catctgatgc tccactatct tttttctctt ccactaagaa aaatagaagt
    16861 ataccacata ttatagatgc tgcagaatat aaccatacta catatttgaa tcctactgtt
    16921 atttcagcaa atttaccaaa gaaataaaga cctataaaag aaattaatgt acctgataca
    16981 cctgataacc cttcataaaa accaaatatt cttccttgct ctgactcact tccttgcatt
    17041 ctaacaacct taacagaggc tgagaagaag gttaatattg tcgtaaatcc ccataataca
    17101 aatattaaaa gtatcatact atatgatggg aatgtagaga aataaaatcc aagtatccct
    17161 gaagcaatta aagaaaaagt tattaatttt ctaactgaga atctatctgc aaaccatcct
    17221 cctataaaat aagataccat tcctactaat ccatataaac tcaataagtt ccctatttgt
    17281 gtatgactta atgctaaagc ttgttgcatt gggtcataaa atgatgattt catatatggt
    17341 aaactataca tagctgttgt tccaaatgcc aatatgaata ttatcaaaaa tcttttaaca
    17401 ttatttttgc tttccattga ttctctctcc ttaaaatttt attgtttata atctcattca
    17461 tataatttta ttttaatttt tctattgctt gtttaaaatc atttattata tcatttgaag
    17521 attctaatcc tacagctatt cttattagat tttccccatt catttgaact aatgtatgct
    17581 cttcccctaa gcttgttgct attgttgcaa gctctaaaga gttcattaat cttctactag
    17641 cttggtctct tgtcaatcca ctgataccat ccttaagttt aaatgaaact acgcctccac
    17701 ctaaaccatt catttgagtt ttacaaagct catattgagg atgtgatttt aatgctggat
    17761 actttaccaa ttccacattc tcttcttcct ctaaaaactc tgctactgct aatccatttt
    17821 cacaatgctt tttcatcctc atatctaacg ttttcatacc ccttaaaatc atccatgcac
    17881 tcattggtgg taaagatgct cctgtaaaac aacataaact tggccatcta actaaatcta
    17941 ttaattcttt tgaacctgct actgctcccc ctaaagtatc tccatgtcca tttataaact
    18001 tagtaagact atgtattact aaatctgcac ctaaatctat tggtctttgt acaattggtg
    18061 tcccaaaagt actatcaact atagctaagc ttttattttc atgagcaatt tctgctattg
    18121 tttttatatc tactaagtct aatgatggat ttaaaggact ttctatataa actattttag
    18181 tatttggtct cattgcttct tttacatttt gtggatttac tgcatctaca aatgtaactt
    18241 caactccaaa tttagataac aactcagaca tgaataattt agtgtgtgaa aatattccat
    18301 ctgaactaac tatatggtca ccacttttta ccaatgctaa tatagtagat gttattgccc
    18361 ccatgcctga tgtactagat atggcacttt ctgcattttc aagcatagcc aacttagctt
    18421 ctaactctgt aagagtagga ttacactctc ttgtatacac atatccccat gtcatacaca
    18481 actcttcaaa atgctctact gtctttgcag caaatgttgc tgtttgacat attggtgtag
    18541 ccaatgcacc tgttgttggg tctgcactat gtccccaatg tattattttt gtctctaaat
    18601 cttgattaat attgttactc attttgattt cctcccattt tgacttattt atacaacgtt
    18661 ttccctgcca aatttcatca atttagctta gtcttaatac attttttcaa gtatactttt
    18721 ttatttgtta taatttctaa aaatatgaca cttattttgt ttttttacag ttctaattat
    18781 aaactctata gtaactatag agtcaatatg tttttgatat tttttttaca atgtttaaaa
    18841 tagtcaatac aaaaataggt atatcttaga ataactaaag tcatcctaag atatacctat
//
LOCUS       DAMJWC010000072        18885 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMJWC010000072 DAMJWC010000000
VERSION     DAMJWC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18885
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.072"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(208..1785)
                     /locus_tag="PC503_002975"
     CDS             complement(208..1785)
                     /locus_tag="PC503_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF2528941.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            complement(2082..4493)
                     /locus_tag="PC503_002976"
     CDS             complement(2082..4493)
                     /locus_tag="PC503_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2528942.1"
                     /translation="MRKYKLKKLSKLLVLLTVCFLIVSTIPVSAEKNKILTGVETAEY
                     SESYLQYLEDVKNGDIAKYNGVIPTPYEMEGTTLKTNVRSSLPASYKSSVSYDPRKLD
                     LTTPAKDQGKLNTCWAFSGMSTLEAYLKLKGYGTYDLSEEHFRWWSTGGIHGWNLTDM
                     TGSSNVTAIGYLTAWAGPKLEKDIPYNFKSEDEGATRPQNMDTAPTQFNVTDVVRISK
                     DKTSVKNAIMQYGAVTSGYAHYSAYLSDDENSYNCNDKSEPLNHSVSIVGWDDNYSKD
                     KFKPSVRPESNGAWLVKSSWGEFNSEKGFFWISYEDKTLLKDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            4683..5084
                     /locus_tag="PC503_002977"
     CDS             4683..5084
                     /locus_tag="PC503_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF2528943.1"
                     /translation="MILKKHLETILYLFFGALTVLINIITYLFFTRIINFTFLLSNSL
                     SWSIAVLFSYITNKFFVFKSEKTEFLFLLKEFVSFLSCRLFSGFIEILLMYLMIDLFS
                     LNDILVKIGTNIIVIILNFVFSKVVVFKHRN"
     gene            complement(5149..7266)
                     /locus_tag="PC503_002978"
     CDS             complement(5149..7266)
                     /locus_tag="PC503_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2528944.1"
                     /translation="MQISKKIISLLTAAFLSIVLPSNVVNASNKDSLIGSGRWETAIK
                     ISQNGWLRSDNAVLVNDNSIADALSATPFAKLKDAPILLSGSKELDFRTKSELKRLGV
                     KNVFLVGGSNALGVNVENELKSEKITVERIFGNDRYETSLKLAEKLNNEKDISDIIVV
                     NGEKGLADAVSVGSIAAQNYMPIILSDSNLGVEVANKFIKAQNIKNSYIIGGLNSISN
                     EIEKNLPNSKRISGNNRNETNANVIKEFYKETDLRNAYITKDGMKKQSDLIDSLSVGV
                     LAAKNNSPVVLVGNKIDSIQKDVLNTKIFSTVTQVGGIGNENVYKDILDMQEETKYTV
                     ETIEELDSALKKVDANDIIKFRPDKKISESFKLETEKAIKVDLYGEYSQSITINMPNG
                     ELNNTGDISKTLILKDIKDGTLTNSGYINQMDISDDNGCKIENENNGQIWIVTIFSSA
                     KDVNIRNDGTITKIDNDSSSTNIRNSGKIDTVSGNKEPGISGNKPNTNNTDKDDDSDT
                     AAGLSPKISACSPLENNQIMLTVPQKPKNSNYKIYYRVLSYKPSAMRVGDRININDWD
                     LVEDTEPLKVNAKNGSYIEVVEIDYTRKKVSRWGRAGATDDGFKIVANGIKSTVSVDE
                     NSKVTISVTGYNGNKVYYRIKTTKPEAMNVGDEIDSSWKSTSNSDIILEGNKVNGLYV
                     ELASGENNKVEKWGATDKIEIVS"
     gene            complement(7297..8004)
                     /locus_tag="PC503_002979"
     CDS             complement(7297..8004)
                     /locus_tag="PC503_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2528945.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAKEIILKYLEEYPEAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDDLELNKTQYVHAP"
     gene            complement(8111..9982)
                     /locus_tag="PC503_002980"
     CDS             complement(8111..9982)
                     /locus_tag="PC503_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HDF2528946.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            complement(10326..12671)
                     /gene="secA"
                     /locus_tag="PC503_002981"
     CDS             complement(10326..12671)
                     /gene="secA"
                     /locus_tag="PC503_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2528947.1"
                     /translation="MSVLDTILDKADEQEIRRLNVIVDKIESLEKDIENMSDDELKKM
                     TDLFRDRLKKGETLDSLLPEAFAVAREASKRVLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVVTVNDYLAQRDKELMQPVYEFLGMSVGVIIADLI
                     PEVRKVQYNCDITYGTNNEFGFDYLKDNMVTKKFDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGEGDEDSKLYELANSFIKTIKEEDYELDRKDKTVALKESGIDKAESFFGIKN
                     LTDIENIELYHHINQALRGHKLMEKDVDYVVVNQEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKDESKTMATITFQNFFRLYNKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPIIRADLHDKVFRTEKEKYQAVVEEVIRIHKTKQPILIGTVSVEKSEMLSGMLKK
                     EGIKHQVLNAKENDKEALIVSKAGKLGSVTIATNMAGRGTDIALGAGDKEEESRVKEL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKSIEKLMKR
                     PNSNKNNSIESKSLTKAIERAQKGVEGKNFELRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQVDIQNMVKDIIKEAAAEYLTKRKRDYYGYFKHLYNTFMPADTLLIPDLDNKS
                     IEDIIDSTYEISKRVYDLKKMVVGLDKITEMEKIVLLKVVDQYWVEHIDAMEQLKQYV
                     GFKSYAQKDPFKEYAMEGYEMFESLNKNIRETTIQYLYKFN"
     gene            complement(12907..15087)
                     /gene="slpA"
                     /locus_tag="PC503_002982"
     CDS             complement(12907..15087)
                     /gene="slpA"
                     /locus_tag="PC503_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF2528948.1"
                     /translation="MNKKNLAVVMSAVTVIGSAAPVFAAAEDSFPNGNTTVSSSKYSD
                     IERILKKYVADGVTGITVNFFDKKGNPKGVSISSLEASQISYVKDEIKDLKAGEYAKI
                     SVKITDGTEKKYDDTLLKELDSNAVVTKVGTATTVKIVDQDGNSIENDAKLKLQKYDT
                     TTSAYVDGATKDEVLAATKAAVKTSKFTDKTGNNATGTVAITATYADAVAGAIKLKYD
                     TQAAVAPTLDTAVASLDGTKEIYDFSKPVITVNTTDGTSKLSFEKTGEKVGAVESNVT
                     VIAASDETVTISGDAKEKAEALAKKYVFKDTELEDAYKTVTASDFEKTDNDYYEVVLY
                     PTGKRLNTASTYASSNYKPELPTSDRVDTPAIITLRSTNKNNLKSALDELRTYNNSYS
                     NNSVLAGDDRIETAIEISKDSYNADGGIKGDYVEANEVVLVGSQSIVDGLVASPLAAV
                     KDAPLLLTSKDKLDSSVKSEIKRVMGLDDKTGITSKKTVYIAGGENSVSKEVANELKD
                     MGLKVERLSGDDRYATSLEIADEIGLNHNKVFVVGGTGLADAMSIASVASNKEMPIVV
                     VDGKGKDLSTDAKDFIGSAYVDIIGGKSSVSEDMEDAIDDATGKSPERVSGDDRQDTN
                     AEVIKTYFEKDNSDSVISTGVKNFYVAKDGSTKEDQLVDALAIAAVAGHNEAPIVLAT
                     DSLSSDQSVAISKVTNSDDSKKLTQVGKGIADSVIKRIKDLLEL"
     gene            complement(15380..16978)
                     /locus_tag="PC503_002983"
     CDS             complement(15380..16978)
                     /locus_tag="PC503_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2528949.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVADQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNVSAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEMYNLVNSYRKEKGKKSLRELDSLAGMANAWSKYMDEKKIFAHEIDGKN
                     AAEVFSGFGMRTDENIAYLPMNVKSVYTSKDAKEIAKSVFDLWKKSSKYNDNMLKEEF
                     YSFGFGMYVSNQREVNATMEFLNS"
     gene            complement(17197..18798)
                     /locus_tag="PC503_002984"
     CDS             complement(17197..18798)
                     /locus_tag="PC503_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF2528950.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPAITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDNKVFEHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKSVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
BASE COUNT         5556 a         3554 c         2014 g         7761 t
ORIGIN      
        1 agattatttt tctttattct agttttgtca atacttttat ttattttttt gttacattca
       61 attccaatcc ccatgttacc tccccaaagc ttattcaaat atatactaaa ctacatattt
      121 atctataaat ctatttgtat ataaacctgt ttaactacat aactttagaa caattacaac
      181 aaacacttca cttaaatata tatattctta gctaagaaat ttctttagaa atccaagctt
      241 atctagtata tcttgtattt tattgacttt ttgacttata gaatctatag ctttttcaat
      301 tgaatctact ttagcctcta aatcttcaac ctgattaact tttttatcta tagtaccatt
      361 attagttata tcactattag atgaattatc tataagtttt cctatatatc catcattaat
      421 caattttgta tcattagcag aagctaatat catcaacgta tctatatctg aatttctagt
      481 attttctata actctaccat ttttgtcacg aactgacaat atagtgattg tatcatggtt
      541 attaaatcca ccttctccaa tatttctaac tataacattt accaaagtag catagttatt
      601 cacttcacca ttaggcatat ctactgtaag agtctttgaa caatcaccct ttatattcac
      661 agttattggt ttatttgtta ccattctaaa agcttcattt acagtattct cttttggttt
      721 aaagtttata atatcattag gacttgctat atttatcata tcagttaatt cctcaacagt
      781 ttttgcttca aacacagttt tttcttgtag acttttaatt tcatcaaaag cttcttcatt
      841 tccatttcca cctacctgtg ttatagtatt taatttttta gtactaagta tgtccctttg
      901 ttttgtgttt aatttattac caaccaaaac aacaggagac tcattttttg cagccaatac
      961 tccaacagct aacgagtcta ttagttgatt ctcattttta ctaccatcct tagttacata
     1021 taaattactt aaatttgtat cagtgtaaaa cttttctatg accttagcat tagtctcatt
     1081 tctatctttc ccactcactc tttctgcatt aggaagactc ttttctacag ctcttgaaac
     1141 agaatttgta cctccaatta catatgcttt tataactttc tcatccctta taaatttatc
     1201 aaatgcttct actccgtcct taggactaga caaaattata ggcatcttat tttgagctgc
     1261 tggtgcccca acgctaacag catcactcaa tcctttttca ccatttacta cagcaacttc
     1321 cttaatatct tttatatcct taagcttatt agccaaaatc agtgaagttt catatctatc
     1381 cttaccatta attctttcta cattaagtcc attacttttt aacttgttct ctatatcttt
     1441 attaagtaca gcagtacctc ctatcaaata aatatcttta gctcctagac gttttatctc
     1501 tttttcagtc ctatcatcta gcttatcact ttctgtcaaa agtattggtg ctcctttagc
     1561 ctttgcaaat ggtgtagctg aaagtgcatc agctaatgaa ttgtcattaa ctagcactac
     1621 attaggacta gaactgtatg ccttttgact tatctttaca gcagtttcat atctaccatt
     1681 acctattaat ttttcctctg taagtgcata tgatggtatt atagaaatgc tacttaaagt
     1741 aagcgctatt gtcagtattg ttaaaatagt ttttggtgct ttcattatta ttccccctta
     1801 ttttgtttaa aatcttacta tatttatatt ataaaataac tttacactat tttacagttt
     1861 aaaattatta catttttcat caataataag aaaactatct aaaaatatag acaatcctat
     1921 ttttcattat ttaaatgata aaaatataaa acaacaaaaa agagtgcctc atgaactaaa
     1981 aagttcattt tgagacaccc cgttttgtta ttttatattt ataaacttct attgaatatt
     2041 ttttaataat aaaatgtata tccttactat ctttccattc actattttcc taaaagagta
     2101 tttagttcat taaaagcatt ttcatttcca tttccaccaa ctctaatagg agtttctatt
     2161 ttcttagact taagtacatt tttttgactt tcatctaact tatttccaac taaaactact
     2221 ggtgaatcag ttttagcacc taatgctcct actgctagtc catctatcaa gtctccttga
     2281 ctctttgaac catctttaac aacaaaagca tatttcaaat ctgagctagg atagaattta
     2341 tctattatct tagcattagt ttcatttcta ttacttcctg caagtcttgt tggatttgaa
     2401 agcttacttt ctaaatttga tgataaagta gctgttccac caattatata agacttagtt
     2461 attttagatg aatttaaaaa ctcatcagca ccttgcaact cactcttttc attagtaagt
     2521 attattggca tattgttatc agcagctgct gcaccaacac ttattgcatc tgcaagtcca
     2581 tttacaccat ttgccactgc aacttgtgaa acagatttta tactatttaa cttttgagct
     2641 agagatatac tggtcttgta tctatcacta cctgaaattc tttctactga tatacccata
     2701 ttactaagtt gagtttgtac attcttgctt aaagaatttt ctccacctat tagataaact
     2761 tttttagttc ctaatctttg taactctgcc ttagtttttg aatctaagtt atcttttcct
     2821 gtcaaaagaa ttggagagtc aattgctgct gtaaatggtg tagctgttaa agcatccact
     2881 attgcatctc catttactaa tactgcattt tgtgaagaag tccatccttt ttgactaact
     2941 ttaactgctg tttcatatct atctgctcca gttaaagatt ctcctgaagt agcttgtcca
     3001 gaagatgttt ttgttatagc ttttataaca aagttacaag gagaaaattc actatatgta
     3061 tttatatctt caaatttatt gttttgaagt atgtagcttt cacctaagtt tgctttagcc
     3121 tcatatagat agtatccatc tatatcagtt tcatatgcta aagttgattt ttctctatta
     3181 ggatttgctg tgttgtctat aactactact attgctcctt taccttttgg taagctgtaa
     3241 gaattagtag gtacatttat gtatccagaa tatgatactg ttccacttgc aagttttgtc
     3301 attgaattgt tttgaggaac tccatttact actggtgcat aatatacttc atattttgct
     3361 cctacagaat ctgtttcaaa cataacagag tcaagttttt cagaatctct gctaaaatca
     3421 aatacatttg ctgctgttac tttatttgac attatcttgc taagaccagc atattcaagt
     3481 tggtacattt ttttatcgct atctggtttt gatactgatt tcattgcgta gttatctgta
     3541 tcttttaaaa gagttttgtc ttcataagaa atccagaaaa agcctttttc tgagttaaat
     3601 tctccccaac tactttttac taaccatgct ccatttgatt ctggtctaac acttggtttg
     3661 aacttatctt ttgaataatt atcatcccat cctacaattg aaacagaatg atttaaaggt
     3721 tcacttttat cattacaatt atacgaattt tcatcatcac ttaagtaggc tgaatagtgt
     3781 gcatatcctg atgtcactgc accatattgc attattgcat ttttaacaga agttttatct
     3841 ttactaattc ttacaacatc tgttacatta aattgtgtag gtgcagtatc catattttga
     3901 ggcctagttg ctccttcatc ttctgattta aaattatatg gaatgtcttt ttccagctta
     3961 ggtcctgccc aggctgtaag atatccaatt gcagttacat tcgaactacc tgtcatatca
     4021 gttaagttcc atccatgtat tcctccagtt gaccaccatc taaaatgctc ttctgaaaga
     4081 tcataagttc cataaccttt taatttcaaa tatgcttcta gtgttgacat tccagaaaaa
     4141 gcccaacatg tattaagttt tccttggtct tttgctggtg tagttaaatc taattttctt
     4201 ggatcatatg atacacttga tttatatgat gctggaagac tacttcttac attagtttta
     4261 agtgttgttc cttccatttc ataaggagtt ggtattactc cattatattt tgctatatct
     4321 ccatttttta catcttccaa gtattgaaga tatgattcag aatactctgc agtttctact
     4381 ccagtcagaa ttttattttt ttctgctgag acaggtattg ttgacacaat taaaaaacaa
     4441 actgtcaaca acaccagtag ctttgacaat ttttttaatt tatactttct catatttacc
     4501 cccttgtatg tatttaattt ttattatatc agatttctaa atctaggtca tattttattt
     4561 ttataaaaat aggaattata attatacata tataaaatac tattttatac tgcatattta
     4621 ttgattaata tgtggtatac taattacata ataatatata ccaaataatg gaggaaaatt
     4681 ttttgatatt aaaaaaacat ctagaaacaa tattatatct tttttttggt gctttaacag
     4741 ttttaataaa cattattact tacctatttt ttacaagaat tattaatttt acttttttat
     4801 tatcaaactc tctatcttgg tctatagcag ttttattttc atatataaca aacaaatttt
     4861 ttgtattcaa aagtgaaaaa actgagtttt tatttctatt aaaagaattt gtatcttttt
     4921 tatcttgtcg tttattttct ggttttatag aaatattact tatgtattta atgattgatt
     4981 tattttcttt aaatgatatc ttagtaaaaa taggcactaa tataattgtg ataattttaa
     5041 acttcgtctt cagcaaggta gtagttttta agcatagaaa ttaacattat tatatttatc
     5101 tttatgcaga ataaggagtt gcctaaaaaa aacaactcct tattagcttt aagaaacaat
     5161 ttctatttta tctgttgctc cccatttttc aactttatta ttttctcctg atgctaattc
     5221 tacataaagt ccatttacct tatttccttc taaaattata tcactattag aagtactttt
     5281 ccaactggag tctatttcat ctcctacatt catagcttct ggttttgtag tctttattct
     5341 atagtaaact ttattaccat tgtatccagt tacactaata gttactttag aattttcatc
     5401 aacagaaaca gttgatttta ttccatttgc tactatttta aaaccatcat ctgtcgcacc
     5461 agctcttccc catcttgaaa ctttctttct tgtataatca atttcaacaa cttctatata
     5521 tgatccattc ttagcattta cttttaatgg ttccgtatct tcaaccaagt cccaatcatt
     5581 tatgttaatt ctatcaccaa ccctcatagc tgatggttta tatgacaaaa ctctataata
     5641 aattttataa tttgaatttt taggtttctg aggtacagtt aacataattt gattattctc
     5701 aagaggagaa catgcactta tctttggaga taatcctgct gctgtatcac tatcatcatc
     5761 tttatctgta ttattagtgt taggtttatt gccacttatt cctggttctt tatttccact
     5821 aacagtatca atctttcccg aatttcttat attagtactt gaagaatcat tatctatctt
     5881 tgttatagtt ccatcatttc ttatatttac atcttttgca gaactaaata ttgttacaat
     5941 ccatatttgt ccattatttt cattttcaat cttgcaacca ttatcatcag aaatgtccat
     6001 ttgatttata tatcctgaat tagttaaagt tccatctttt atatctttaa gtatcaatgt
     6061 tttacttata tcacctgtat tattcaactc tccatttggc atatttatag ttattgactg
     6121 actatattct ccatataaat caacctttat agctttttca gtctctaatt taaaagattc
     6181 acttattttt ttatcaggtc taaactttat aatatcatta gcatccactt tctttaaagc
     6241 agaatccaat tcttcaattg tttcaactgt atatttagtt tcttcttgca tatccaatat
     6301 atctttatag acattttcat ttcctattcc accaacctga gtaactgtac taaatatctt
     6361 agtatttagt acatctttct gaatagaatc aattttattt cctactaata ccactggaga
     6421 attgtttttt gcagccaaca ctccaactga tagtgaatct attaaatcac tttgtttttt
     6481 cattccatcc ttggttatat atgcatttct taaatctgtt tctttataaa attcttttat
     6541 aacattagca tttgtttcat ttctattatt tcctgatatc ctcttagaat ttggtaaatt
     6601 tttttctatt tcattagaaa tggaatttaa tcctccaata atataagaat tttttatatt
     6661 ttgggctttt ataaatttat tagctacttc aactccaagg tttgaatctg aaagtataat
     6721 tggcatgtaa ttttgagctg ctattgaacc aacacttaca gcatctgcta atcccttttc
     6781 tccatttact acaattatat cagaaatatc tttttcatta ttcaattttt cagccaattt
     6841 taaggatgtt tcatatctat cattcccaaa aattctttca actgttattt tctctgattt
     6901 taattcattt tctacattta cacctagtgc atttgaacct cctactaaaa atacattttt
     6961 tactccaagc ctttttagtt ctgattttgt cctaaaatcc aattctttac ttccagatag
     7021 taaaataggt gcatctttca atttagcaaa tggagttgca gataatgcat ctgctattga
     7081 gttatcattc actaatacag cattatcaga tcttaaccaa ccgttttggc ttatttttat
     7141 tgctgtttcc catctacctg aacctattaa actgtcttta ttagatgcat ttaccacatt
     7201 actaggtaaa acaattgata aaaatgctgc tgttaataaa gatattattt tttttgatat
     7261 ttgcattaat tatctcctcc taatttaaat ataattttat ggagcatgta catactgtgt
     7321 tttatttaat tctaaatcat caaaatgaga ttttactgaa tggtatccta tagcataatg
     7381 tccactttca ggattccatt tcttatatgc attcatcgca cttaataact tctcctcttg
     7441 actaggtaat accttccaga cttctacatt tggattaact tttttaaaat ccttatagtc
     7501 atatggttct acataaaatc ttaaatcttt tatttttcct tctctatata actctagtgc
     7561 agcttctcct aatgctctat gatcttcatg tattccacta gctttaaacg gagtaacagt
     7621 ttttactttt gcttctggat attcttctaa gtatttaagt attatttcct ttgccttttc
     7681 tttgcttaac tcaccatcat gagctctatt atcttctata tgtatattac tttcttttac
     7741 acccattgct tcacagctat ccttaaattc ttcatctcta tcttttgaaa attcactttc
     7801 tgataaagag tatttatgaa catctttaat atgataagaa catgaccctc catcatccaa
     7861 aacttttctt attatagatt tactaccatc tgtgcacaat atgacatgtg tatcactttt
     7921 ttcaacatgt tcaattatag cacttcccat acttaaggtt tcatcatctt gatgtggtgt
     7981 aaaaaacaaa gttgcatcta ccactactac atcctcctac tttataaaat gttataattt
     8041 acaataaata gcataattat agaaaaagat tcctgtatta attaaggaat cttctccaca
     8101 gtataagtta ttaccaacct agtattttag ctatcttttg tattactgtc aattcaactc
     8161 cattacctat ttgagttact tctgcaccaa gatttaattt tttactaagt gcattctttt
     8221 gtgagtctgt tatatcagtt ttagctagaa gtattggacc tttacctgct gctagaggtc
     8281 ctgctgccaa tgcatctact agcataccat tatttccata tccatctttt gctatatata
     8341 gtttatctaa tttgccataa tatgtttcta taactttagc attagtatcg tgtcttgttt
     8401 ctccttcaac tctttgaact tttctatctt tatcaatatc tgcaagttga ttttcaattt
     8461 ggctagatac attattagag ccaccaacta tgccaatctc ttttccatcc atcaatttga
     8521 tagcatctgc tgatagatca ttccaaccat ttactattat aggagcctta agttcagcag
     8581 ctttagcagc tatactcata gcatcagcct ccccttttgc gcctactaca aatgcatctt
     8641 taaaagaccc catagctttt gctactgcta cagaagtcat atgtctatca tctccagcta
     8701 gtctttcaac attcttagtt actgattcta attgcttttt agctgtattt gatactgctg
     8761 attctccacc tactatatat attttagctg atgggctttt cttaattata tcttttatat
     8821 aatctaaagt tacttttggt atttcattat cagatgctaa taatataggt gcttttttag
     8881 attgagcaag tggtgtagct gctaatccgt caactagttt atttgaatta actataacta
     8941 tattgtcagt atattttgtt tgttttgcta tagccactgc agttgcatat ctatcatctc
     9001 cagctatcaa tttaaccttt gaattacctt ctaatgcagc tttggcatct tttaaatctt
     9061 tttcattggt actttctaca gtaagctctg ttgcttttcc agatgcatca gtatacttaa
     9121 tagtaaattt atattttcct gtttctgaat cttttgctga aatatcacta attgactttg
     9181 atgtaccatt tgctaccata ttacctttaa cagtcaatct atatccatca tataaatctt
     9241 gtggtgaaac tgtatttagg tcactatttt ttatagttat ttcggccaat tggacatcat
     9301 caatattttt agctcctgct acacctagtt tatcgatttt atttactcta aatccttctg
     9361 cagaagggtc taaatttgtt ccagttgaat caactggatt tgctgttaaa tcaacttttt
     9421 catcaccaat acctacatat atagttttag aagttactgt ttctgtttta tctcttaaag
     9481 ttataactaa cttatcttta gcactatcat atgaagcttt tacatctgca actttataaa
     9541 ttccattggt ttcagtttta gctttttctg ttatagaatt agcctcagcg gaaaggtctg
     9601 ctgaattttc atatttttca gttgcttctg caactacttc atttgcacta tttgttatat
     9661 gtcctttatc tgttatagtt acaataagtt ctttattttc tcccaaagca tttactaatt
     9721 tctctaattc atctatatta gttattattt ttaattttga taaagtctca ccaactttta
     9781 tttcatatat tggttgtcca acttgagaac ctcctgtata cttttgagac attaaacctc
     9841 taactttcga aactaattct gtagcctctt tcttagttat tgtttctttt tttacctgtg
     9901 tagtttctgc agcaaaaact ggagctactg atgtacttat cattgcagca gccataatta
     9961 cagaaagatt ttttttattc atggtatttt ccccctaaaa aattcaaatt tttattattt
    10021 tttccttatt taccaattat aatatatatt tgatattatt tcaataaatg agacttattg
    10081 taataattaa ccaaaagata taaacttttt cttatatttt atttttttaa tatttacgta
    10141 tacaaaaaag taacaaaatt gtaatttttt ttaataatcc agtttataac taatagactt
    10201 ttcatcttct ttatagtata atattaaatg gaagaaagaa atttcaagca tctctttttt
    10261 ccgtatttct cacatagaaa aagaggctga ttatcagcct ctttttccta tacagtttaa
    10321 atttcttaat taaatttata taaatactgt atagtcgtct ctcttatatt tttatttaat
    10381 gattcaaaca tctcataacc ttccatagca tattctttga aaggatcttt ttgagcatat
    10441 gatttaaatc ctacatattg ttttaattgc tccatagcat ctatatgttc tacccaatat
    10501 tgatcaacta cttttaaaag aacaattttt tccatttcgg ttattttgtc aaggcctact
    10561 accatctttt ttaaatcata aactcttttt gatatttcat aagtactatc aattatatcc
    10621 tcaatacttt tattatctaa gtcaggtatt agtaaggtat cagctggcat aaatgtatta
    10681 taaagatgct taaaatatcc atagtaatcc ctctttcttt ttgttaaata ttcagcagca
    10741 gcttctttta ttatatcttt aaccatgttt tgaatatcta cttgtatatc ttcatcattt
    10801 agaactttat ttctttcgtt atagattact tttctttgtt catttatagt atcatcatat
    10861 ttaagaacat ttttccttaa ttcaaaattt ttaccttcca cccctttttg agctctctct
    10921 attgcctttg taagagattt actttcaata gaattatttt tatttgaatt tggtcgtttc
    10981 attagtttct ctatactttt tccaccatac aatttgatta catcatcttc aagactaaca
    11041 aaaaaccttg atgttcctgg atcaccttga cgtccagaac gccctctaag ctgattatcg
    11101 attcttctag attcatgtct ctcagttcct attacataaa gtcctcctaa ttcctttact
    11161 ctactttctt cttctttatc acctgctcct aaagcaatat ctgttcctct acctgccata
    11221 ttagttgcaa tagttactga acccaactta ccagcctttg acactatcaa tgcttcttta
    11281 tcattttcct tagcatttag aacttgatgt tttattcctt ctttcttaag cataccagat
    11341 aacatttctg atttctcaac agaaacagta ccaataagaa ttggctgttt tgttttatgt
    11401 atccttatta cttcttctac aacagcttga tacttttctt tctctgttct aaacacttta
    11461 tcatgaagat ctgctcttat aattggtttg ttagtaggaa tttgtacaac atttaattta
    11521 taaattgatt caaattctcc ttcttcagtt ttagcagtcc ctgtcatacc agaaagttta
    11581 ttatataatc taaagaaatt ctggaatgta attgtagcca tagttttaga ttcatctttt
    11641 atttctaccc cttcttttgc ttctatagct tggtgtaagc catctgtata tcttcttcca
    11701 tccattactc ttcctgtaaa ttcatcaact atcattactt cttgattaac aacaacataa
    11761 tcaacatctt tttccataag tttgtgaccc ctaagagcct gatttatatg atgatataat
    11821 tctatatttt ctatatctgt aagattttta atcccaaaaa atgattctgc cttatcaata
    11881 ccactttcct ttagagctac ggtcttatct tttctatcta attcataatc ttcttctttt
    11941 attgttttta taaatgaatt tgctaattca taaagttttg aatcttcatc accctctcca
    12001 gcaattataa gtggagttct agcttcatct ataagaattg agtcaacctc atcaactatg
    12061 gcaaaattca actctctttg tactttatca aactttttag ttaccatatt atcttttaaa
    12121 taatcaaatc caaattcatt atttgtacca taagtaatat cacaattgta ttgaactttt
    12181 ctaacttcag gtataagatc tgcaataatt actcctacag acatacctaa aaactcatac
    12241 actggttgca ttagctcttt atcacgttgt gctagatagt catttactgt aacaacatgc
    12301 acacctttac ctgttaaagc atttagataa acaggtgcaa cttctaccaa agttttacct
    12361 tcaccagttt tcatttctgc tatttttcct tgatgaatta caatgcctcc aattaattga
    12421 accctatatt gacgcattcc taaaactctt tttgaagctt ctcttgccac tgcaaatgct
    12481 tctggtaata aactatctaa agtttctcct ttttttaatc tatctctaaa taggtctgtc
    12541 atttttttta attcgtcatc agacatattt tctatatctt tttctaaaga ttctatttta
    12601 tcaactatca cattaagcct tcttatttcc tgctcatctg ctttatccaa tattgtatcc
    12661 aaaactgaca tatttaattt acctcctttt ttatcataca attactatta taccttaaaa
    12721 ttatagaata gtagacaatt atttttattt atagtataat aatcatactt aaataaatta
    12781 catctttaat tatttaggta tttctcacaa aaaaaggaac tatttttagt tcctttttta
    12841 atttcttttt ataaaaaaga gaacttcttc aaagaagttc cctcttattt atagtttaat
    12901 tttatcttat aattctaata aatcttttat tctcttaata actgaatctg ctattccttt
    12961 accaacttga gtcaatttct tagaatcatc agaatttgta actttactta ttgctactga
    13021 ttggtcagaa gataaactat cagttgctaa aactattgga gcttcattgt gacctgctac
    13081 tgctgctatt gctaacgcat ctactaattg atcttctttt gtagaaccat ctttagcaac
    13141 atagaagttt ttaacacctg tgctaattac actgtcacta ttatcttttt caaaataagt
    13201 ttttataact tctgcattag tatcttgtct atcatctcca ctaactcttt ctggactctt
    13261 acctgtagca tcatctatag catcttccat gtcttcagaa acactagatt ttccacctat
    13321 tatatctaca taagcacttc ctataaagtc ttttgcatca gttgataaat cttttccttt
    13381 tccatcaact actactattg gcatttcttt attagaagca actgatgcta tactcattgc
    13441 atctgctaat ccagtaccac caactacaaa tactttatta tggtttaaac ctatttcatc
    13501 agcaatttct aaagatgtag catatctatc atcaccagat aatctttcaa cttttaatcc
    13561 catatctttt aattcatttg ctacttcttt agatacagaa ttttccccac cagctatata
    13621 aacagtcttt ttagatgtta taccagtttt atcatctaat cccattactc tctttatttc
    13681 agattttact gatgaatcta acttatcttt tgaagttaat aataatggag catctttaac
    13741 agcagctaaa ggtgaagcta ctagaccatc tactattgat tgtgatccta ctaatactac
    13801 ctcattagct tctacataat ctcctttaat tcctccatct gcattataag agtctttact
    13861 tatttctatt gcagtctcta ttctatcatc accagctaat acagaattat ttgaataaga
    13921 attattataa gttcttaatt catctaaagc tgattttaag ttattcttat tagtagatct
    13981 taatgttatt atagcaggag tatctactct atcacttgta ggtaattctg gcttatagtt
    14041 agatgatgca tatgttgaag ctgtatttaa tcttttacct gttggataaa gaactacctc
    14101 ataataatca ttgtcagttt tttcaaaatc acttgctgtt actgtcttat atgcatcttc
    14161 taattcagta tctttaaata catatttttt agctaaagct tctgcttttt cttttgcatc
    14221 tccagatatt gtaactgttt catctgatgc tgctataact gttacatttg attcaactgc
    14281 tccaactttt tctccagttt tttcaaaact taattttgat gtaccatcag tagtattaac
    14341 cgttataact ggtttactaa aatcatatat ctctttagta ccatcaagag atgctactgc
    14401 tgtatctaaa gtaggtgcta ctgctgcttg tgtatcatat tttaatttaa ttgcaccagc
    14461 tactgcatca gcatatgttg ctgtaatagc tactgttcct gtagcattat taccagtctt
    14521 atcagtaaat tttgaagttt tgactgctgc ctttgtagct gctaaaactt catctttagt
    14581 agctccatct acataagctg acgtagttgt atcatatttt tgtaacttta atttagcatc
    14641 attttctatt gaatttccat cttgatctac aatcttaact gttgttgcag taccaacttt
    14701 agtaactaca gcattactat caagttcctt taataatgta tcatcatatt ttttttctgt
    14761 tccatctgta atttttacag atatttttgc atattctcca gcttttaaat ctttaatttc
    14821 atctttaaca taacttattt gacttgcttc taaacttgat atagataccc cttttggatt
    14881 tccttttttg tcaaaaaagt taactgttat gcctgttaca ccatctgcaa catatttttt
    14941 aagtattctt tctatatcac tatacttact actagataca gtggtatttc catttggaaa
    15001 actatcctct gctgcagcga aaactggtgc tgctgatccg attactgtaa cggcagacat
    15061 tacaactgcc aaatttttct tattcattcc ttaaattcct cccaacatta tattaattac
    15121 atctctttaa ttatgtacat taaaattcca tgttcatata aaccaaatat ttctcacact
    15181 cttatgatag actatataaa atagaatttc aataatttat gcaaaattaa tagaattttc
    15241 tttcaacatt tttccccttt tttttgctat ttcatatttt ttaaattaaa ttttcaattt
    15301 taattttatt aatacattta tttatctgat ttaatcaata tatattaata ttttctacca
    15361 taaaatatta atatatactc taactattta aaaattccat tgtagcatta acttctcttt
    15421 gattagaaac atacattcca aagccaaaac tataaaactc ttcctttaac atattatcat
    15481 tatacttaga agacttcttc cataaatcaa atacagactt agcaatctct tttgcatctt
    15541 tagatgtata tacagactta acattcatag gtaaatatgc aatattttca tcagttctca
    15601 ttccaaagcc agaaaatact tcagctgcat ttttcccatc tatttcatga gcaaatatct
    15661 tcttctcatc catatactta gaccatgcat ttgccattcc agctaaagaa tctaattctc
    15721 ttaaactttt cttacctttt tcttttctat atgaattaac tagattatac atttcattag
    15781 ataccatagc cttaaactca taactattag ggtcttttgt acttgtgttt ataattactt
    15841 tgacatttac attaatctca cacttttgcc caaaattatc aaaagcactt acatttaaaa
    15901 catacgttcc tgccttactg gtatccacag ttccctcaat attaggcttc aaattatttc
    15961 cataataatc agtggcaact atattcaaca tactattatc aaacttatcc cctacagaaa
    16021 tctctacatc attagcagtg attgtaggca ttgtattttt atcagatgca gaactaatac
    16081 attggtcagc aaccttctta tccattccac ctaaagaagt aacttcatca gcacctctaa
    16141 gcacactctt atcacttcca tcattaacaa gtactatagg tttgtcctta gccaacggag
    16201 aaccagccac agcatcaact aacttatacc cttgagaaac ataaaacttc tttgttcctt
    16261 tataaaagcg ttgtataacc ttcttattag tttcaaatct atctttacca gcaatcctaa
    16321 cagaattagt cttactcaca agttcattac tcattatctc ctctgaccca agagaataac
    16381 attgaacgcc atcaacctta aatggtatac tctttccatc agtaagtata acaggaactc
    16441 catctctagc agctacagaa gatacactca ttgcatcagc ctcacctgtg tatccattta
    16501 caagaaaaac cttatcacca tcatttactg gtttaatagc tgaaatctcc ttagctataa
    16561 gatagctagt ctttattcta tcttccccac caattctttt aacttcaatc cctttattct
    16621 taagttgatt ttctacagat ttacctattg tatcctctgt acctataaca taagcattct
    16681 taacatcctt tagtcttttt tcaacatctg ttggtatctt atctctttgc actaacatta
    16741 taggagcttt tacaactcca gataatccac ttgcacttaa tccatctact atagaattat
    16801 cagtatttac taatatgact gtatcatata tttgtttatc tgctatcaat gcagaagtct
    16861 catatctatc tttcccttgt atcttttcta tactcgaaag tgcattgata tttggtgctc
    16921 ctgccattat taatgatatt gtcaatccta ttgataatac tctcttattt accttcatcg
    16981 aactcctcct actaattttt ttatataatt cagctaatca taaattacac cctcagtagt
    17041 gattccctca aaatttataa actactaaaa caaaaaacac ctaaaatacc ataacctgta
    17101 aagcaataat aaaacagatt acaaaaagta ctttagatgt gattttcatt ttataatatc
    17161 agtaaattaa caaaaaaaca agatttatgg aattttttac aagctacctt cattgccatt
    17221 taaaaactct tgagtagcat gcacttgacc atcagataat atataaagcc caaatccagt
    17281 actataaaac tcatcactaa gcatgtttgc attgtattct ggagatttct tccacacttc
    17341 aaatatagcc tttgccaagt cttttgcatc ttgagttgtt tgaacactct tagaatctat
    17401 ataaatatat gctatatttt cctcacttct cattccaaac tcagaaaata cttgtggagc
    17461 atttttgcca tctatataat gttcaaaaac tttgttatcc atcatatact tagaccatgc
    17521 atttgccata ccttctagct tactagatac taccaaaggc tctttacctt tttcttttct
    17581 ataggaattg attaagttat acatttcagt agataccatt tttttaaatt ctgggctgtt
    17641 gtaatcatga gatttatcat ccaacacttt tatttctact ctttttcctg tactttttcc
    17701 ccattcgtct gtagctttta atgtcaatat gtatgtacct actctatttg tatctataaa
    17761 cccatcaact tctattggta ataccttccc agtgttatct ttagctacta tatttaactt
    17821 gccagtgtca aacttttcac ccttatatac ctctgtactt ccaactgtaa ttgctggggg
    17881 ttgtccattt gactttgaag cacttataca ttgttgtatt accttctcat ctatttcacc
    17941 tacagaggtt atattcttag ctccttctaa tacagtttta tcgcttccat catttactag
    18001 taccattgga gagtttttag taagtggtgc agctgctatt gcatctacta attggtatcc
    18061 atctgataca tagaatccat ctgcactatt aaaaaagtag tctattacgt ttttgttagt
    18121 ttcaaatcgg tcagttcctt ctattcttac tgagtttgta tttttaacta gaggattact
    18181 cattatctcc tctgaaccta tacaatatga ttgaatattt tttacatcaa aaggcacact
    18241 ctttccatct gtaagtatga ttggagctcc atctctagta gctactgatg atacactcat
    18301 tgcatctgct tctccactat atgcattagt tagtagtact ttatcaactt tttttatagt
    18361 tgctatttct ttagctatta aatagcttgt ttttagtcta tcttctccac caattctttt
    18421 gacttctata tttttagaat ctagttcttt ttctactgat ttacttatag tatcttctgt
    18481 acctattata tatgcttttt tgatattttt tagacatcta tttgtgtctg ctggtatctt
    18541 attttgttgt gtaaatagta ttggagcttt tgtagctccc gataatccac ttgcacttaa
    18601 tccatctgca agtgattttt ctgtatttac taaaattact gtttcataag tctgtttatc
    18661 agctatcttt gctgctgttt catatctatc tttaccgtat attttttcta ctactgatga
    18721 tgcatttaca cttttgaagt ttactaagat taatgatact gctagaccta atgataatat
    18781 ttttttgttc attttcatat ccccctgatg atttttatat tttatattta tattgtgatt
    18841 attttccatt tattttctct ttattttcca tatattatag agtat
//
LOCUS       DAMJWC010000073        18702 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMJWC010000073 DAMJWC010000000
VERSION     DAMJWC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.073"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..605)
                     /gene="yqeC"
                     /locus_tag="PC503_002985"
     CDS             complement(<1..605)
                     /gene="yqeC"
                     /locus_tag="PC503_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF2528951.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRNKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHRTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKV"
     gene            complement(788..2065)
                     /locus_tag="PC503_002986"
     CDS             complement(788..2065)
                     /locus_tag="PC503_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2528952.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASFNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2204..4510)
                     /locus_tag="PC503_002987"
     CDS             complement(2204..4510)
                     /locus_tag="PC503_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2528953.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKILSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4503..5297)
                     /locus_tag="PC503_002988"
     CDS             complement(4503..5297)
                     /locus_tag="PC503_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2528954.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5404..6762)
                     /locus_tag="PC503_002989"
     CDS             complement(5404..6762)
                     /locus_tag="PC503_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2528955.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8109..9158)
                     /locus_tag="PC503_002990"
     CDS             complement(8109..9158)
                     /locus_tag="PC503_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528956.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQ
                     EMIVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEI
                     NVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITV
                     MKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMK
                     EIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            complement(9388..10473)
                     /locus_tag="PC503_002991"
     CDS             complement(9388..10473)
                     /locus_tag="PC503_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2528957.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10509..11822)
                     /locus_tag="PC503_002992"
     CDS             complement(10509..11822)
                     /locus_tag="PC503_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2528958.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11823..14114)
                     /locus_tag="PC503_002993"
     CDS             complement(11823..14114)
                     /locus_tag="PC503_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2528959.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14104..14898)
                     /locus_tag="PC503_002994"
     CDS             complement(14104..14898)
                     /locus_tag="PC503_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2528960.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMTKALVVRMYNSIGGECDGK"
     gene            complement(14937..15383)
                     /locus_tag="PC503_002995"
     CDS             complement(14937..15383)
                     /locus_tag="PC503_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2528961.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15455..16861)
                     /locus_tag="PC503_002996"
     CDS             complement(15455..16861)
                     /locus_tag="PC503_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528962.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     IRGTIKNRMEGHKWNSLY"
     gene            complement(16879..18249)
                     /gene="hydA"
                     /locus_tag="PC503_002997"
     CDS             complement(16879..18249)
                     /gene="hydA"
                     /locus_tag="PC503_002997"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2528963.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKIAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18382..>18702)
                     /locus_tag="PC503_002998"
     CDS             complement(18382..>18702)
                     /locus_tag="PC503_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2528964.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKS
                     VYGK"
BASE COUNT         5610 a         3642 c         1981 g         7469 t
ORIGIN      
        1 actttattaa taaataatac tctttttcca gaataatttt taaataatcc atttggattt
       61 aatactatat tttttaagtt ttcaatactt actgtagaac tactattaat actacttgta
      121 tctaaatttg ctattttttt aaatatttct actctatgta tattctcttc attaatattc
      181 attccaaatg atgttatatc taatatccct atggtttttg tagttctatg atatactact
      241 ggttctttag cattccaacc tttaagtttt tttctctttg agccatctcc ctctattaaa
      301 actaaatcaa attggtctac aatttcatcc aaaatagagg aatcaatact tactaattta
      361 ttttcattat ttatataact gccacagact gttattccat gacaaataga tggaataaca
      421 gttccatcta ttgtaataat tatattgtca taatcgtttg gtacatatat tttagttgtt
      481 gttgtaagaa gaactttcaa tttatttcta taaaaatttg caaaatagtt tataaacgaa
      541 gtttttcctc ctgctccaac tacagttatt atttcattct tttctattat atttgatagt
      601 tccacacttt cacctcttat aaccagtttt ctaatctctt aattattata gttaggcctt
      661 tttagtaaaa gtgatttttg aaattccata aactcgaaag taaatagatt ctgttgtaaa
      721 caacaaggcg gatccaattc gccgctaagc tgtaagctta cgctatcagt ttatctttta
      781 aatataatta agatattctt actctctgtg gttgctttaa tatttgagga ttattctgta
      841 aattagataa attaactact tgtgattttt ttagtatatt aaaactcgca tttacatctg
      901 catttataat gattccaaca ctggatttgt actgtccacg tgttattctt tcccctttaa
      961 agtcatattt tttaacattg tccacattga tatcaggtag aaaatcatca gcaaaaaaat
     1021 ctgatttact agtatagctt tcttcttgcc taataaaatt gatatttttt attttacaca
     1081 gatattctaa ttttcctttt atctctccaa atgggattct tataaaattt ctatatattt
     1141 ttctctccat attatcactt ttttctaact tagcattata tcctacaatt aaatttccaa
     1201 tattattttt tacacaataa tcaattatat aaaaacaggt tttatttaca tagtctttaa
     1261 cttgattatt tctcttattc caaactttaa attgttttct tgttattgca gttatattct
     1321 tttttaattt taaggcttct attttatcat tctgtttgtt tgcccactga ttcacagatt
     1381 ttagcctttt tccatctatg ataaaactat cacctaaatt ggtaacacat gtacataaat
     1441 tttctaaacc caagtctata gctagtgcat ttttttgatt tgaaacttcc tctgattttg
     1501 gtatttcata acaatactga atttcaaaga acctagcttt atgtttaggt attattctta
     1561 tttctttaat ttttttctct agtatatttt gtggaacttt tatacttact ttcccatata
     1621 gttttttaaa tgctggagac ataggtacat ttaaaatccc atcttctttg attcttattt
     1681 gacctattat tatgctaaaa aatccttctt tatctaaata tttaggtgat tttatccctc
     1741 taaagtcata ttttccttct ttggctaatt taattaatcc aaaaaatgac ctaaacgaac
     1801 tgtctacttc ttttaatatt tgttgcgcta tattactatt gagaagctta tagttctcat
     1861 tttctttgca tacatgataa ttagcttcat agttaagatg ttctccttga ttgaaataat
     1921 gctgtcttac attatatgta ccaacattat ataagttctt agctaagaag cacatctctc
     1981 gtagagcttg atattctttt ttagttaagt tttttaattg ttgtctctga gttccatagt
     2041 gtatattttt tattctgttt gacatgaact cacctccttt agaatatact ctactagaca
     2101 ttatatacgg tatttttaca aaacaccata tataatgtcc atttaattac tttattttac
     2161 aaaataattt aaatttactt gcttttatgc atcttattat ttattataat tgtttattat
     2221 tatttttcat acccatataa actttttcaa aagtcatagg aagctctctt aaacgaactc
     2281 ctgtagcatt aaatattgca tttgctatag ctggtgctgg tgtatgtata actatttctc
     2341 ctaatgattt agcaccataa ggacctcctg ggtcgaaatt ctcagcaaaa tctaccaata
     2401 tatttccaac ttcttttttt gtaggaactt tatactgtag gaaactatct gttaataatc
     2461 taccatcttt atcaaatata gggtcttcat acattgcaaa ccctataccc atcatcacac
     2521 caccttctac ttgtattcta gctaaagttg gatttataac tgttccacaa tcaggtacac
     2581 atgcaaaatt tatgacttta tattcacctg tatttttatc taattctatc tctgcaaatc
     2641 ctgctataaa tggttttatt tttttcaaca tgccaaaaga ttctgttgct tccaaaacta
     2701 ctggtacatc atcactagca aatcctattc ctccaacaga ttctctaccc aattcctcta
     2761 atagaacaaa cttgctatta tcgtttttaa caaaaaccct gtcttttccc aactctaaat
     2821 cttctttttt aaatcctagc tttgactctg caactgaaag taatatatct tttaatttat
     2881 ttgctgtctt tattgttgca tttcctgtaa ccgttgtcgt acaagaagca aatgctcctg
     2941 tatcataggg acataagtct gaatcacctg tataaataga aattctatct acagtagtat
     3001 ttaaagcttc cgcagcaatt tgagcttgaa ttgtatcagc cccttgacct aagtcagcaa
     3061 gaccagataa tattttatat gtgccatctt catccattct tatagtgact gttgccatat
     3121 ctacacgcgg tataccagaa ccatgatttg ctactgccat acctactgct cttactttgt
     3181 tgtttcctat atctttacat ggatatttat catcccaatt aattaatttc tttccctttt
     3241 ctatacattg tctcagctca caacttaata tttcgtcttc agctgctttt ccattggtat
     3301 acctatctat tatattttta attctaaatt caagtgggtc cattccaatc ttatgtgcca
     3361 attcatcaat agcactatct attgcaaata ttccctgtgt agcaccatac cctctaagtg
     3421 ctcctgctgg taacctatta gtatatactg ttctagcatt aaatctaaca gcatcaatat
     3481 cattatatat tggtaaggta ttgtgtccag attcggaaga aacagagaca ccattcccac
     3541 cataagcacc tgtattgttt aatgacttta gctctattgc ttttaaattt ccttctttat
     3601 ctgcaccaac tttaacatca aaaaacattt catgtctact attagaacct acaaaagttt
     3661 cacttcttgt aaatacaaat tttgctggtc taccagtttt catagtaaca aatgcagtaa
     3721 atatatctgt tgctgctata ttctttcctc caaatccacc acctattcta ggtttaatta
     3781 ctcttatttt tgaagacggt atacccaata cttttctaag tattctcttt acattgtgtg
     3841 gtgattgtaa tgatgaaact acaacaattc tatcatttat atctttatat gaatatgacc
     3901 tatgagtttc catcatgcaa tgcgattgac tttgggtttt gtatgaagat tcaaccacaa
     3961 aatcactttc tttaagctta gcttcaacat ctccaaattc aaaaaattct tttgatacta
     4021 tattattttt tgcatccaat ccaaaagggt atggctctac tatgtctttt tctggatgta
     4081 taacaacttc atttccttct gcttctcttg catcaaacac aggctttaaa acctcataat
     4141 ctacctttat catttttaag gctttaagtg ctgttttctc atcttcagca gccactaaag
     4201 ctacttcatc tccaataaat ctaactgtat cttcaagtaa aactctatca taaggtgatg
     4261 cttctggttc tgtttgacct ggaacacaat atctgacctg tggtacatct ttatacgtat
     4321 aaatacccac aacccctgga attttttcgg cttttgatgt atctatattc tttatcttag
     4381 catgagcatg tggacttcta agtagtttta atgtcaaaac atctttatgc ataatgaggt
     4441 cttcagtata tagaggtttt cctgtgacaa ttgctgtact atctatcttt cttatcccct
     4501 tattaatcat tatacattcc ctcctcaata gcattataca tccttttaac taatgcactt
     4561 gccatatcct ttctgtactc tttactagct ctcatattac ttccataagt aagttcctta
     4621 ctagcaacaa tagatgcctt atctatatct ttttctttat ttaatatatt actcgcttca
     4681 agtgctaatc tagctttttg aggtcttgcc ccaattgcta ttttgtaagt atcattttct
     4741 tttagcattg ctgaatttaa tacagaaaaa tctcctgtgc attttcttat tgagtcaaaa
     4801 acagctattg catctttttt tggtagtatt acttcgacca atatatccct acttaattca
     4861 ctatccaaaa actcacttaa ctctagtatt cctttattgt ataatctcac cttcgctcca
     4921 acaaccaaaa gtgctggtat taagtcagaa aagccatact ttgaaaatac acttgcacca
     4981 attctagccc cttgtctaaa ttgaacacca actatattag aaacagcgct tgaaagtatt
     5041 ccactacagt aattttttat agttttatca atttctaaac ttctaagtga agtatctgca
     5101 cctatcaaaa tatttttttt atcctctttt atataattta gatttatatc ttttaaatct
     5161 atcgctgttc ctatattttt attacttaat tttataaatc cacatccacc taaaataaca
     5221 ttattttttt tagaaattaa aattttatat gcttcttcta aactctgtgg aactgaatat
     5281 tcctttatag taaccatctt atccccccat cattaactta ttaaaacaca aaagttttta
     5341 ataaatcttt tatttatatt tataattgta gtatatttaa ttcacatata ttaaaccttt
     5401 acattataaa cttttatttt tatcctcaac cttatcactt ttatttccag gaaattttac
     5461 catatataaa gcttgaatta ttatggctac cattgctcct gaaactacac ttgaatctgc
     5521 aagtaatgtc tctataaatt ttggaaattt ttcaagaact tgaggagcta ccatgaatcc
     5581 aataccagaa gccatagaaa gacctaatat catgctattt tcttgattaa atccatccat
     5641 actaacaagt cttaaaccag atgttgtaag agttgaaaat ataacgagtg ttgctcctcc
     5701 aaccacacag ggaggaattg ttcttattaa attagctaat aaaggcgata ttcctgccaa
     5761 aaataatcca attcctccaa tagctagtac aaatttactt acaacctttg tattggaaac
     5821 gattgcagaa ttttgtccaa acatccccat tggagttgca gaaaataatg cacctattgt
     5881 agagagtact ccatttccta aaacagcaga agaaagttct tcatctgtta cttgtctatt
     5941 aagccctcct accgcagaaa gtgtacaagc acccattata tcagctatct caactaaata
     6001 tattattgaa aacattacaa caacttcaag tcttatatct agcccaaaag caagtggttt
     6061 tggaagtgca accaaagtaa actcctgaat tgaagaaaaa tttactatac ccaaaattaa
     6121 tgataaaatg tatccaaaaa ttatgctaac taatattgat gcatctttaa ataatccttt
     6181 tccatactta tttaatccta atatcataag agatacagat attccaacta taaaattaat
     6241 tggattccca aaagtctcat tgcccatacc cccagctaag ttttttatag ctattggaaa
     6301 aagtccaaga cccatacatg caactattgt tcctgataca gctggagtaa atataaatcg
     6361 tattttttta agaccaaaac caattataat tattactata ccagctatta tttgagagcc
     6421 aaataatact ggtagtccat acttacttgc aacagatacc ccagctccta taaacatagc
     6481 tgtagctccc attataactg gtattcctcc tcctaattta aaacctttaa acaaaggtat
     6541 tggatataat tgtaataaag ttgataatcc tgcaaaaact aatgcggctt gaatcaataa
     6601 tgttgacatc ttatgattaa gtccagctgc atttgcaatc aatatcgctg gtaaacaact
     6661 acctattacc attgccatta agtgttgtaa ccctaaaggt attgcttcct ttagtggtgg
     6721 tattccgtct aattcaaatt ttgatgtact ttttgctttc ataataaaaa ctcccgttac
     6781 ataaaactta ttgaattata taaatactta aaaatctaat atattaaatt aatgatgttc
     6841 ataaatatca actatactcc aacatatatt taagttttta gtcttaaaaa acagatgcaa
     6901 taaatttaat tattaacaaa tacacgtatt ctttaatttt gtatacatta tataccatgc
     6961 tttacaaata taagagtatt atagctatga atttttaatt ttttatagta aatttaattc
     7021 aatttaaatc tttcaatctt aatcattata agttataagt tttcataagt atttacatgt
     7081 ttcaagtttt aaacatttac ctataaacgc tactttatag atgtcacttc aaatccagtg
     7141 acctcatact ttcatatgag cgtagactat ttcttcatct tcagcattac ctgctaagag
     7201 caacccgttt ccactatcaa tcgcttatag tgtactctct ctcgagatag tcgtttgacc
     7261 ttcctatttc taggcttggc gaccaaatgt ccatttttaa gtacttaggc tctcaccata
     7321 taccatcctc actattgttt ctggttttca ccacattcat aaaagtttct ttctatcttt
     7381 tattgtagtt gcaaggcttt aggatttact ggttttaaag ttgtgtccta catagatttc
     7441 tctatgtacg gggccaaaag tacaatttat ttaacatact ttgctttacc ccctgtaaat
     7501 aatattattt actctttcac tgtttttgtt attaaattaa ttaaatatca attaatctaa
     7561 gcataaaata attatttaat ttaaactcaa aatatttatg aatattttat aatataattc
     7621 tcataagaca gaaaaactta ataagctatg tatctcagtt gtaccaatgt actctccttt
     7681 actatatttg tatctgcaac ataaaatata caagtttcta tctatttata gatatatata
     7741 tctataagca aaatagtaat attattttta tagtaaaaat tttattcata ttactattta
     7801 taatttttat agagcaattt tagtgccaat atttgcatac atttgtatag tataaaattt
     7861 ttatgttctc attgataaaa ttttacttat ttcaagcgtt ctattagatt ttatcatcta
     7921 aattttaggt tttattttta taaattaatt gtatttacat aaaaaaaaag acctaaaaac
     7981 aaatttttaa cggtcttttc tcaatttttt attttcattt ctaaaattta taataaatag
     8041 taagaacact ataaattctt ttatataaaa ttcttagttt gtggatgata aattagtgaa
     8101 ttaaaatact actttactga ttttagtttg acaatatcac tccaattttt actagtggct
     8161 aactctacta aatttaagtc tcttcttatt tcagctatat cctcttttat agaattagtg
     8221 tcacctttta tatatgctat gttatgttct atattatcat gagtagcttt atttatttca
     8281 gaattatgta ataaacttcc taaaatatta ttctgttcta tctgtatctc tttcattgat
     8341 ttatcttcac attctagact atcaatctta atttcaattc catataattt ttcatttgct
     8401 atggatacct cgtccttaat tccattcata tcttcattaa tgttatttat tttattttgc
     8461 ataaagttta cttctgattt aacttcggaa acatcttctt tcattacagt tatttcttgt
     8521 ctcacttctg acatgtcttt tttcattaca tttatctctt gttttacctc tgatgtatct
     8581 tctttcatta cggtcatttc ttgtcttact tcggacatat cttctttcat tatatttatc
     8641 tcttgtctta cttcggacat atcttctttt aatacattta tctcctgttt tacttccgac
     8701 atatcttctt tcattacagt catttcttgt cttacttccg acatatcctc tttcattgta
     8761 tttatctctt gtcttacctc ggacatatcc tctttcatta tatttatctc ttgtcttacc
     8821 tcggacatat cttctttcat tacaatcatt tcctgtttta cttctgacat atctcctttt
     8881 aatacattta tttcctgttt tacttccgac atatcttctt tcattacagt catttcttgt
     8941 ttcatttccg acatatcttc ttttaataca tttatttcct gttttacttc cgacatgtct
     9001 tctttcatta cagtcatttc ttgttttact tccgacatat cttcttttaa cacatttatt
     9061 tcttgtttta cttccgacat atcatttttt atgctaacta catcttcatt tatagtatat
     9121 aataactcta aaatcttctc ttgcacttgc atcaccatcc ctattaatta ttataacatt
     9181 ttacacaaat gctatacaat gttaacatat atatcagaat tattaaaatt ttaattaaac
     9241 aaaattgatt cactttatta cttcaaaact aattaatatc taaaataact acaaataaac
     9301 aaaaataagg tcaacaacaa aaaaggctta tctctttgag atagcctttc ttatttttat
     9361 ttaaaacttt gttttttata aaataatcta tacattcagc tctgaacatg aaatttttct
     9421 tccaagtgct tttggtttac aaactgatat acaaagtcca caatatctac actcttcttc
     9481 attcaattcc atcttatcat tcaattttct cgcttgatat gcacaaactc tctcgcacat
     9541 cttacattta gtacattttt cttcatcata agtaaactca aagctaagtc tttcattaac
     9601 atctcccata tgattatgta ctataccaca agcattttct atagtattat atcctaatct
     9661 attaagatta gattttaaat catcatgtat tttagatatt acttgtgcac cttttaaaat
     9721 tactactgaa catataccaa caaagtcagc acctgccata atcatttcta aggcatcatc
     9781 tccacttaca catccaccta agccaattat tggtatatta acttgttttt ttatttcata
     9841 tattctctgt aaagttattg gcttgatagt ttctccactt aaatatccta ttccatttcc
     9901 acctaataaa ggttgccctg tttctatgtc tattctaaat gctggtccta cagagtcaca
     9961 agcagttatt gcatctgctc ctgcttcttc taatttttta gcaaaatcgc ctatctcatc
    10021 tatcatagga ggaagtttaa ctattacagg tatatttact ctttcctttg catctttaag
    10081 cattggtatc aaatctctat agtcataaga tactaattca ataaagtcag ctcctgcatt
    10141 tgcaactttc tctactaatt cgctactttc ttcaattgta tgacctattg aagctataca
    10201 gacagtccca tctcttttca tttgtggtat ttcaaaatct atccattgct ctggctcaaa
    10261 atctgtccat ttttcattat ttaaaagagc attagctgta tttctaacca tatgtggtgc
    10321 tggatttata gctctttctt ttcttatagt cttagtcaca actgcccctg ctcctgcatc
    10381 acttaatatc ttgcatccag ctgcactata tgttaatggt cctgaaccta ttataagtgg
    10441 tgattttaat tctttaccta aaaaattata cattatctgc ttcccctttt catatatatt
    10501 tacattcgtt aaaatttcca aaattcacaa gcaacttctt tcatttcttt aacaatagct
    10561 tttttatcta aatcaactaa ctgtttttct tttaaaatat gtctaccatc tatgtataca
    10621 tttgatataa attctttttt accctgaact actatctggt caaatatatt atcaagagtc
    10681 acaggagttt taaattcatc ttccataact attatatcag ccttattacc aactgctatt
    10741 ttaccagaat tttgaagtcc taatacataa gcaccatgct ctgttgccat tctaaatact
    10801 aaatttgctg gcattactga tgcatcttct tcaactgatt tatgcattaa aaatgcacct
    10861 ctcataactt caaaaaaatc atttatatat ccatcagtac ccagtgccac ttttatgcct
    10921 tttttaatca tttttggtac tggagaaaaa cctccaccta cttcacagtt actaagaggc
    10981 atatgaacca cttttacgcc tttttctttt aatatatcta tttcttcatc atttactttt
    11041 acacactgag atgctaatac agtttcatcc aatatatcta aatcattata gtagtcaact
    11101 gcttttttgc caaagtgttt ttcagcatag tttggctcat atatactctc acataaatga
    11161 aattgcattg gtgcatttaa tttttttgca tcttctttag ctttcttaat aaatctatca
    11221 gaacatgtga agcttgtatg tgtacacatt attccattta ttaatttact attttctcta
    11281 ctccacttta ttaaattaga attttcatct aaacatctaa gtccattttc aaagcttatt
    11341 ctttcacaac tttctaagga taaaatcgct ttcatgccta tttcttctag tatttttcct
    11401 tgctcaatta aagttccttc ttctgtattt ggagcttcta gggtatcaca aaaagctacc
    11461 acaccagatt ctataagttc tattgctgat gctttagttg ttgccttcac ttcttttaat
    11521 ccaattctat tttctataaa tggccaccaa tagtcattta aaaaaccttc aaagtcagta
    11581 aaatgtacat ttgccggtat tcccctagaa agaactccat attgatgcat atgaccattg
    11641 acgaatcctg gcattattat agcatctgat ttatctatta tttcttcaat atttttatat
    11701 tttatttcaa cttcttcatt tggcaatata tcttttataa tgtcattttc tactacaaca
    11761 gcagaatttg tatatatttc atcagcagaa gatattaagt atttactttt aatagcaatc
    11821 atttatttac ctccctgatt taattttttc atggccatat aaactttctc agaagttata
    11881 ggaagttctc ttatacgaac tcctgtggca ttgtatattg catttgctat tgctggtgca
    11941 ggtgtatgaa taactatttc tcctaaagat ttagctccat atggacctgt tggctcataa
    12001 ttatctacaa aatcaacaat tatgtttcct atatcttttt ttgttggaac tttgtattgt
    12061 aatagattag aagtttgaag ctttccatca gaaccatgtc tagggtcttc atacattgca
    12121 agccctatac cttgagttac accaccttca acttgtattc tagcaagtgc aggattcata
    12181 actgtaccac aatctgtaga acaagcataa tttattactt taaactcccc tgttgtttta
    12241 tctaactcta tttcagcaaa tcctgctaag aatggtttag cactctcttg tataccataa
    12301 gattcagatg aatataaaac ttcttgattt ccaccaccaa cagattcttt tcctaattca
    12361 cttaacaaaa caaacttctc tacatcttca ctataacaaa ctctgtcttc atatagtatt
    12421 aaatcatcta ttggtaaatc gagtttcttc tgtgctactt ttaatatctt ttgttttaaa
    12481 ctttcagcag attttattgt agcatttcca gttacataag tagtacaaga agcgtatgca
    12541 ccagtatcat atggacacat atctgtatct cctgtataaa cggaaattct atcaatagat
    12601 gtattcaatg cttttgcagc tatttgtgca agtattgtgt cagaaccagt tcctaagtct
    12661 gaagacccag aaaacaactt ataagttcca tcttcatcca tcctcatatt tactattgcc
    12721 atgtctatgt tggctatacc agaaccatga gttcccacag acattccaac agccctcacc
    12781 ttattgtttc caatatccct aacagggtac ttttcatccc atccaataag ttttttacct
    12841 ctaattatac attcatcaag tgcacaactt cttattggaa aattcattat tccgccttca
    12901 gtttgttttt ttataatatt ctttaacttt atttctgttg ggtccatatt aagtttatgc
    12961 gctaattcat caattgcaca atcaagtgca aatgtacctt gtgttgctcc atatcctctt
    13021 aatgctcctc ctggaactaa attagtatat acagttttcc catcaaattt tattgcaggt
    13081 acattattat atgttggaag tacattatga cctgattcag agcaaactga aggtccatta
    13141 tcgccataag cgcctgtatt gttcaatgct ttcatatcta tagcttttat gtttccttct
    13201 ttatctgccc caatttttat atcaaaaaac atctgatgtc tagtattagt cattgcaaaa
    13261 gtttcttctc tagtataaat tagttttgct ggtctttttg tcatccaagt tacaaatgat
    13321 gcatatatct ctgttacagc tatgtttttt ccaccaaaac ctccacctat tcttggtttt
    13381 attactctca cttttgaaag aggtattccc agtgctttag aaacctgtct tctcatatga
    13441 taagctgatt ggtttgcaga agttactact aatctgccat tcgtatctat atacgtataa
    13501 gctctatgag tttccatcat acaatgggct tgtgattgag tcatataaga atgttctact
    13561 attacatcac tttctttaaa ctctttttct acatcccctt tacccatttt ttctctcgat
    13621 acaatatttt ttgtagcatc caatccaaaa tcaaatggac aaaacaaatc atcttcttca
    13681 tggattaaaa ttttatttcc ttccgattct cttgcatcca atataggagt cattacttca
    13741 tattcaactt ttataagttt catagcttta atagcagccc tttcatcttc agcggctatt
    13801 atagcaactt catctcctac atatctaact acgtcttcaa gtattaattg gtcatgaggt
    13861 gatgcttctg gatatgactc tccaaccatt gaatatctat aatttggaac atctttgtaa
    13921 gtgaatatgt ttactacacc ttttaccttt aatgcatttt ttatatctat gttttttatc
    13981 ttcgcaaaag catgtggact tctaagaagc ttaattgtta aaacatcttt atgaaaaatt
    14041 aaatcttctg tatatattgg ttttccagta acaatggctt cactatctat ttttcttacc
    14101 tctttattta ccatcacact cacctccaat actattatac attctcacta ctaaggcttt
    14161 tgtcatatct tttctgtatt ctttacttcc tcttatatta cttccaaatg aaagttcttc
    14221 acttgatact tcaccagctt tttctatatc attttctaaa cttaatattt cacttgcttt
    14281 ataggcaatt tttgctcttc ttggtctagc gcctatcgca attttataaa tacttccttc
    14341 ttttaacatt gctccattta atactgcaaa atcacctgta cattttctta tagaatcaaa
    14401 tacacctata gcatcttttt taggtaatat aacttctatt aatatatctt tttcaagctc
    14461 attttctaaa aaatcagcta agttcataac ccctttttta tataacttaa cctttgcatc
    14521 taccactagt aatgaaggta ttaaatctga aaatccatac ttagcaaata cgctagctcc
    14581 tactctagct ccacttctaa attgaactcc tactatatta gaaacagcgt ttgaaattac
    14641 cccattacag taatttttaa taaccttatt taattctaaa gttcttaaac ttgtatctgc
    14701 tccaattaat atgctatcat cagtttcatt tatataatct aaagctaagt cttttaaatc
    14761 tattgctgaa ccaatatttt tactacctag ttttaaaaat ccacatcctc caagtattat
    14821 gttgtttttt cttgatatta gcagttcata agcttcatct aaactttttg gaactacata
    14881 ttcctttata gttatcatac tctctcccca tatcaactta attttcactt aaaagtctaa
    14941 gtgtttaaat atttatgtat tgctcttaat tgacctttat atcctgtaca tctacaaagg
    15001 ttaccattta cataatctat aacttcttct tctgttggat tttgaagctc tcttttcatt
    15061 gccaagacca tcattataaa tccaggagca caaaatccac actggtcagc cccttcgtct
    15121 gcaagaaaat ctccaaactt ctttgcttca tccaagacac cctcaagtgt tgtaatatgc
    15181 tgaccttcta ctctagcagt aagataatta catgaaagca cggccttgtc atttaccatc
    15241 actgtacata acccacatga gcctgtatca cacccttttt taacacttac atatccattt
    15301 tctcttaatg tatctgctaa aaaatcatct ggtcttatac ttaattcttt ttctttatta
    15361 tttatggtac atttgataat caaataaatc acctcaaaac tcatattttt aagctaaagt
    15421 tttactatac ttttttatga ataaattaca tttattaata aaggctattc catttatgac
    15481 cttccattct attttttata gttcctctta tacaaagtct ctcagctgta tcttgagcat
    15541 cttttaatgc tttctcttca ttagctgtca atatttttga atcttccatt attatatttc
    15601 catctactat aacactctct atatttttca tactagaaga atatactaat gtagataccg
    15661 gattatgcat aggtatcgct tttggtgaaa gcattggatt aaatattagt aagtctgctt
    15721 ttttacctat ctccaatgaa cctatctcat cttccattcc aatagctctt gctccatcta
    15781 tagttgccaa ctcaagaact ttttctgccg acattgctaa tgggtcacac ttattaactt
    15841 tatgttgaag tgctgttaat ttcataagtt caagcatatc ttgagagtta ttactagcgg
    15901 ctccatctac tcctaaacta actgttattc cttttttaag catttctggc actggtgcaa
    15961 cacctgaaga taagtacata ttacttgctg tattatgaga cactttcata tcgtattttt
    16021 tagtaagttc catatctttt tcagttagat acacacaatg taccataagc acatttggtc
    16081 caagtattcc taatttttct aaaacatcta tgtcatattg cccatgcaat tcttttgctg
    16141 cttctctatc aaaaggagtc tctgatatat gtactgtaaa taaagcatca tcatattctt
    16201 ttactactct ccatagcatt tcaagcattt cttgagaatt tgaccatatt gctgcaggag
    16261 ctactcctat tttgattctt ccattttctg tattatggtg tttttcaaac aatcttctta
    16321 catctttttc aaccgtttct acatcttgca ttattccagg atgaactcca aattgagctc
    16381 ctgtattcat acatcctctt ccaagtattc ctcttattcc taattcttta taagcatcta
    16441 ttattccatc acaaagacct ggcttactat gaggatacat gtagtcaacc attgttgtta
    16501 taccacttct aagtccttca atacatccaa gcattgcagc atcataagta tctttgggct
    16561 ctaaatagtt agctgctgga aatgtcatag tttctaacca gtctttaagt accatatcat
    16621 ctcccaatcc ttttaataaa gtttggaata aatgattatg tgtatttata aaacctggga
    16681 ataaaacttt acctttagca tctataattt ttttaacatc agtatattta ctttctatct
    16741 ctttagaatt tccaatatca gcaatcttgt tatcttttac tactaatgcc ccatcaaaaa
    16801 taacttctct ctctttattc acagttacta ttatggcatt cttaataagt atatccatca
    16861 ttcttatttc cccccgcatt atttagtaat ttttctttta atatattgac ctgttggatg
    16921 ttctttaaca ttacaacttt gtactacatg atttcctctc aaaaatacat cttcaacttt
    16981 acatttaacc ttaaatcctt catatggagt ataatctaca ttttgttttt gagttttata
    17041 actaattgtt tcttctttat tgatatttaa aatgactata tctgcatcac ttcctacagc
    17101 tatctcacct tttttaggat acattccaaa tatttttgca gcattcgtag aagtaacttc
    17161 cacaaactta tttacactta ttctattttc taagacccca tatgtatata aaagtgctaa
    17221 cctatgttca acaccaggtg ctccatttgg tatcttactg aaatcatcaa ttcccaagtc
    17281 tttttgcccc ttaaaattaa atgaacagtg gtctgtgcca actgtttgaa tatctccact
    17341 agacaatcct tcccaaaggt aatttatgtc ttcttttttt cttaaaggag gagacattac
    17401 atacttagca ccctcaaatt tatccttatt atataaattg tcttctaata atagatactg
    17461 tgggcatgtt tctactatca tatctatatt tttttctcta gctattttta cagtttcaag
    17521 tgactcccta caacttaagt ggactacata ggattttgaa ttagataatt tagttatatc
    17581 agcaagtctt gaaacagact ctttctcaac tatgttaggt cttgtaagtg gatgatattt
    17641 tggctccaaa ttaccatttt gtatattttc ttctatcaat acatctagta aatccccatt
    17701 ttcacaatga aatccaacta tacaacctaa atcccttgct ttctttaaaa ccctgtatat
    17761 tgttccatca tctactttca tgccatcata tgccatatac atcttaaaag atactatccc
    17821 atctgaaata agtttttcca tatgattaaa tgtatcttta tttaaacatg taattgtcat
    17881 atgaaaacca taatcacaat aacaatttcc acttgctttt ttatgatatg cttctacacc
    17941 ttgcagtaga ttttccccct cattggcttc tgcaaaatct agtattgtag tagttcctcc
    18001 agctatagct gctcttgttc ctgtttcaaa attatctgca gttgtaatag aacctgcatt
    18061 catatcaaaa tgagtatgtg tgtctattcc accaggaatt acaattttac ctgtagcatc
    18121 aataacctta tcaccattta tttctaagtt atttcctatt tcaactatct tttcatcttc
    18181 tatccttaaa tcacttatat aagtcttatc agaggtaatt atagttccac ctcttagtat
    18241 tgttcccata tatacctcct aacttttaag ctttaaagta ttttctaagt attgtaaaac
    18301 tttatttaaa attgtatttt ctaaaggtgc tatattcagc acctctagac tatatttaaa
    18361 taatttattg tgaactaaat attattttcc gtatacagat tttaatattc catagtaacc
    18421 ttctgttcct ataaataact gttcttgctc tatatactca tctattgtgt gagcaagatt
    18481 ttccttagaa ggaccaaatc ctatagtttt tattccagct tcacctgcat agtgacttcc
    18541 attcgtacag aatgagtatt gagttatttc tgaatctatt ccagcttctt ttaatccctt
    18601 atacgctgct tgaacaaatt catcttcttc gtcatataac caacctggga agaatctttc
    18661 actttctata gtatttcctg tatagcaatc agctttttca ac
//
LOCUS       DAMJWC010000074        18692 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMJWC010000074 DAMJWC010000000
VERSION     DAMJWC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18692
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.074"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..321
                     /locus_tag="PC503_002999"
     CDS             <1..321
                     /locus_tag="PC503_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2528965.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            337..1920
                     /locus_tag="PC503_003000"
     CDS             337..1920
                     /locus_tag="PC503_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2528966.1"
                     /translation="MRILIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1948..3276
                     /gene="ssnA"
                     /locus_tag="PC503_003001"
     CDS             1948..3276
                     /gene="ssnA"
                     /locus_tag="PC503_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF2528967.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3475..4827
                     /locus_tag="PC503_003002"
     CDS             3475..4827
                     /locus_tag="PC503_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2528968.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5019..6128
                     /locus_tag="PC503_003003"
     CDS             5019..6128
                     /locus_tag="PC503_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2528969.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6411..7802
                     /gene="hydA"
                     /locus_tag="PC503_003004"
     CDS             6411..7802
                     /gene="hydA"
                     /locus_tag="PC503_003004"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2528970.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7796..10357
                     /gene="xdh"
                     /locus_tag="PC503_003005"
     CDS             7796..10357
                     /gene="xdh"
                     /locus_tag="PC503_003005"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF2528971.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10509..11855
                     /gene="rpoN"
                     /locus_tag="PC503_003006"
     CDS             10509..11855
                     /gene="rpoN"
                     /locus_tag="PC503_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF2528972.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12637..13659
                     /locus_tag="PC503_003007"
     CDS             12637..13659
                     /locus_tag="PC503_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2528973.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13719..14726
                     /gene="gap"
                     /locus_tag="PC503_003008"
     CDS             13719..14726
                     /gene="gap"
                     /locus_tag="PC503_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2528974.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            14948..16150
                     /locus_tag="PC503_003009"
     CDS             14948..16150
                     /locus_tag="PC503_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF2528975.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16176..16919
                     /locus_tag="PC503_003010"
     CDS             16176..16919
                     /locus_tag="PC503_003010"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF2528976.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16928..18460
                     /locus_tag="PC503_003011"
     CDS             16928..18460
                     /locus_tag="PC503_003011"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF2528977.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         7484 a         2159 c         3764 g         5285 t
ORIGIN      
        1 gttgaaaaag ctgattgcta tacaggaaat actatagaaa gtgaaagatt cttcccaggt
       61 tggctatatg atgaagaaga tgaatttgtt caagcagcgt ataagggatt aaaagaagct
      121 ggaatagatt cagaaataac tcaatactca ttctgtacga atggaagtca ctacgcaggt
      181 gaggctggaa taagaactat aggatttggt ccttctaagg aaaatcttgc tcatacaata
      241 gatgagtata tagaattaga ccaattattc aaaggtgcag aaggatatta tggtatatta
      301 aaatcagttt ataaaaaata attaggagat ggttttgtga gaattttaat aaaacatggg
      361 cttatagtag atggaaataa aacaccagca tatgaaggag atattttaat agaaaacgag
      421 aaaatattaa aaatatcaca agatttaaac gaagaagctg acaaagttat agatgcaaaa
      481 ggtagagtta tatgtccagg tttcatagat actcatagcc attcagacct agttatttta
      541 gttaatccat ataatgaggt aaagattaga cagggaatta caacagaagt gttgggccaa
      601 gatggtatat ctatggcccc tctacctcaa gagcatatat cttcttggag aaaaaattta
      661 gcaggtctag atggtgaaag tgatgaaatt gattggaaat atgaaacaac agagaattat
      721 ttaaaaatga tggattacaa tggggtaggt ttaaatgaaa cttatttagt acctcatgga
      781 aacgttagaa tggaagctat gggacttgaa gatagacctg ctactaaaga agaaattcaa
      841 aaaatgtgtg aaatcacaga gagagaatta aaagcaggag ctataggatt gtctactgga
      901 cttatatata taccttgtgc atactcattg actgaagaaa ttatagagat gtgtaaggta
      961 gtagcaaaat atgatggagt atttgtagtt caccaaagaa gtgaagcaga tacaatttta
     1021 acttcaatgg aagaaatcat agaaattgga aaacaatcag gagtaaaagt tcatttttca
     1081 cattttaagg tttgtggtaa agcaaactgg aagtatatac cacaagttat agagctttta
     1141 gaaaaagcag aaaaggaagg aataagagta tcttttgacc aatatccata tgcagcagga
     1201 agtacaatgc ttggagtagt tttacctcct tgggcacatt ctggaggaac tgataagtta
     1261 atagaaagat taagtgatga aaacgaaaga gcaaaaatga aaaaagatat agcaaatgga
     1321 atagaaggct gggataattt tatagaattt gctggaatag accaaatatt tgtaacaagc
     1381 gtaaaaacag aaaagaataa agatacaatt ggtaagaact tattagaaat tggaaaaatg
     1441 agaggaaaag acccattaga tgcaacgttt gatttattaa aagaagaaga aaatgcagtt
     1501 gggatggtag atttctatgg attagaagaa catataatag gattcatgaa aagagacgag
     1561 caaaatgtgt gtacagatgg tcttttagca ggtaaaccac atccaagagc ttatggttct
     1621 ttccctaaaa tactaggaag atatgttaga gagttgaatg tgttaacaat cgaagaagct
     1681 gtttataaaa tgactaaaaa ggcagctaca agctttagta taaaagatag aggcgaatta
     1741 aaagaaggat attttgcaga tatagttata tttgacaagg atacagttag tggttgtgat
     1801 gattttatca actctatgca gtaccctaca ggtatagatt acgtaattat aaatggaaat
     1861 tgtgttgttg aagaaggaaa atacaataaa attaaagcag gaaaagtact taaaaattaa
     1921 atcttagctt taaggaggaa taaatttatg attttagtgg ggaatgggag gctaataagc
     1981 caagattctt taaatcccta tatggaagat ggatgtgtag taataaatga taatctaatt
     2041 gaagatatag gtactacaga agaaatgaaa gctaaatatc cagtacatga atttatagat
     2101 gcaggcaaga aaataatcat gccgggtcta ataaattcac atatgcatat atacagctca
     2161 tttgctagag gaatggcagt tccaggaaaa ccttctgaga actttttaga gatactaaac
     2221 aatttatggt ggagacttga caaacagctt acactggaag atacaaaata cagtgcatat
     2281 gcaacgtata tagaatgtat aaaaaatggt gtaacaacag tttatgacca tcatgcaagt
     2341 ccaaatgcaa ttgaaggcag tttgtttaca atatcagatg ttgcaaagga tttgggaatt
     2401 agaacgtgtc tttgttatga agtgtctgat agagatggtg gaaatacaat ccaacaaggt
     2461 atcaatgaaa acgtaaactt tataaaatac gctcaaaaag atgatacaga catgataaaa
     2521 ggaatgtttg ggcttcatgc tgcatttaca ctatctgatg atacattaaa taaatgtgct
     2581 tcagagatgg ctggtcttga tacaggttac catgtacatg ttgctgaagg actagcagac
     2641 ttacaatata atgtagataa atatggaaaa agggttttag aaagattcaa tgattttgga
     2701 gtactaaaag aaaaaacaat agcagttcat tgtatatata taagtgcaga agaaatcagt
     2761 cttttaaata aaacaaatac atttgtagtt cataatccag aatctaatat gggaaatgca
     2821 gttggatgtt ctcctgcaat agagttatta aaaaggggag ttacagtagg attaggaact
     2881 gatggatata ctagcgatat gtttgaatca ttaaaagttg ccaatataat tcacaaacat
     2941 cacttaaaag acccaagagt tggatttgaa gaatcacaaa caatgttatt tgataacaat
     3001 agaaaaatag ctaaagctta ttataaaaat gacctaggag tacttaaaaa aggtgcttat
     3061 gcagatgtta tagtagttga ttatatacca catactccat tgacagaaaa tacaataggg
     3121 ggacacacta tttttggaat gagtggaaga agcgtagata caactattat aaatggaaag
     3181 gtacttatga aagatagaaa gttaataaac atagatgaag aaagtattct agcaaaaagt
     3241 agagaattaa gtcaaaatct atggaataga atttaaataa ttgattatgc aaaattctat
     3301 gaagcaggaa ccctgtgact ttagtcatgg gaggttcaga ttaatataca agtaagaaac
     3361 aagaatttag atgttaaaaa cagagcttaa acaaaaatag gaatttaaat gaagtatata
     3421 aataaaaaat atacggaata gaatattaaa ttaaatatag aagggagacc caaaatgtct
     3481 cgagataaaa gccctaaaat agctccagta gatgaaaggt tacctgtatc caaatcttgg
     3541 gtattttcac tacagcacgt tttagcaatg tgtgcaggag cagtagcagt tcctatgatg
     3601 ataggaagtg ctgcacgact agatcatgct agtattgttt ttttaataaa tgcttgcttg
     3661 tttatggcag gtataggaac actcatacaa agtgttggta taggaaatat tgtaggtgct
     3721 aaaataccag taatagaagg aactagtttt gccgctgtgg caggtatgac agcaatagcc
     3781 tcatcatata gtgattcaca agttgcaata cagacagtat ttggctctgt aatagtagct
     3841 ggattgtttt gtatattact tgctccagta tttgaaaaat taataagatt tttccctagt
     3901 gtagttactg gaacagttgt tatggtaata ggtatttcac tatttccagt tgggataaaa
     3961 tggataactg acaacaaatt ggaagcggtt gaaccaaact cattagcatt agctttagca
     4021 gtattggcaa taactttact ttcatttaaa ttcttaaaag gaatttggaa tagcacagct
     4081 atattggtag gtatagtact tggtacacta ctttccatgg cagttggaat ggcagatttt
     4141 agtgcagtaa atggagttgg ttggcttaac ttaaatgtac ctttaaaatt tggaatgcct
     4201 agatttgaac catctgcaat actatcattg tgtttgatta tgttggtact tatgacggaa
     4261 tcagttggta atatgatagc tattcatgaa atggtagaca aagaagtaac aggtaaaaat
     4321 attaaaagag gtctatttgg agatggaata tctacagcat tatctggaat attcaattca
     4381 tttccaataa ctccatttgg tcaaaataca ggaatagtag gtcttacagg tataaaatca
     4441 agatttatag cagtttacgc aggggttata ttgctagtac ttggattctt accaaaattt
     4501 gcagcaataa taggagcaat acctaagcct gttcttggag gcgtaggatt tgcaatgttt
     4561 ggaatggtaa tggttggagg agtaaaaact ttaagcaaag tgaaatttga tggaactaaa
     4621 aatggggtta tagtagcagt tagtgttggt ttgtctatga taccactaac aaatcctgat
     4681 ttctatcata atttcccaac ttgggtacaa acaatattcc atagtggaat aacaacaggt
     4741 agtttatcag cagtgctttt aaacatattc ttcaatgaac taggttctaa aaaagaaaaa
     4801 aataataaag ttgaagaagc aaaataaaaa taaaacaagt aaaaatctat attgacttaa
     4861 agtcattaag tattaataaa aataattcag agatattaat aattcaacaa aactatctta
     4921 tattttaaat aatataaaaa agtaaataaa taacaaatac aaataaaaga atacaatcta
     4981 aatattaaaa atatttaatt taagggagag ataataatat ggctaattta aaagttaatt
     5041 tatatggaat ggaattttta aatccaatta tgacagcggc aggacctgga gcaaaagatg
     5101 gtgctctctg tcaagaggca gcaaaaggtg gagcaggagc tatatgtaca aaaactatat
     5161 ctgtattacc agctgatgta ccaagaccat gtatggcaaa aactaatagt ggttttttaa
     5221 acacagaatt atggtcagag cttccaaaag agcaatggat agaggaagaa tacaaaaagg
     5281 taaaagaaac agggcttcca gtaatagtaa gtatgggata ttcagcagag caaatagctg
     5341 aggttgctcc tttagtaaag ccttatgcag atgcagttga attatctact cattatgtag
     5401 gtacagacgt tgcaccaata gtaaatgctt taaaagctgc aaaagctgtt ttagatgtac
     5461 cagtatttat gaaaatgagt cctcatactg acattcaaac tattgcaaaa gctgttgaag
     5521 aagcaggtgc agatggactt gtaatgataa actcatttgg accatgtatg gcaatagatg
     5581 taaatacagg ataccctata atgggaagta aagctggata cggatggtta tcaggtgcac
     5641 caataagacc tctagcaata agatgtatat atgaagcttc tcaagttgta aatataccaa
     5701 taatcggtgt tggtggaatc acttgtggaa aagacgtggc tgaaatgatg atggctggag
     5761 caagtgctgt tcaagtatgt acagaagcaa tccttaaagg gccttctatc tatggaaaaa
     5821 ttgctaaaga attaaatgaa tttttagatg agaatggata tgctgatgtt aatgaaataa
     5881 aaggactaac tcataagaaa atggcagcta gagggtttag aactcattca gtagctccag
     5941 tagtggatga taacaagtgt atcaaatgta agcaatgtgt aacaagctgt gtatacgaag
     6001 ctttagaagt tacagataag ttgaacatag atgcagacaa gtgttttgga tgtggattat
     6061 gtgtaactag atgtccaaaa ggagctttaa gcatctgcta caatcaagta gaagctatga
     6121 atgagtaata attatataga attttggtaa ttaacttaga gtaataggta ttaggataat
     6181 aaaatatatc agataaacaa acacacatta tgcattaata atacagtcta aagttaataa
     6241 ttttattata ttgatttaac taaatattag tttagctgaa tattaattta attaggtatt
     6301 ggtttaatct taatatagat ttactgcgta taagtgaact aactagatta ctttaagtta
     6361 attttttcat ataaaataaa ttgatacatt acaagtaagg tggagtctat atgggaattg
     6421 ttttaaaagg tgggaaagta gtaacaagtg aaaaaactta ctgtgcagat gtaagaatag
     6481 aagatgaaaa aatagtcgat ataggtcttg atatatcaaa agaaaatgat gaaatagttg
     6541 atgttagtga ttcttatgtt ataccaggag gtatagatac acacacacac tttgacttag
     6601 atacaggcgt tactaagaca gcagataact ttgagacagg aacaaaagct gctatagtag
     6661 gaggaactac tactatattg gattttgcta cacaagctaa aggatgttct ttgaaagacg
     6721 gattagaaga atggcatgaa aaagctaagg ataaatccta ttcagattat ggctttcata
     6781 tggctataac agattggaat gactcggttt gtaatgaaat ggaggatatg gtgaaagagg
     6841 gagtatcttc atttaaactg tatatggcgt ataaaggaag ccttcaagtt gatgatggtg
     6901 taatctttga agcattgaga aaagcagaag agataggagg gattattggt ttccattgtg
     6961 aaaatgggga cataatatgt gaacttgtgg ataaagcaaa gtcagaaaat aatttatctc
     7021 caaaatatca tcaattaact agaccagcta taatggaggc agaagctaca tcaagactta
     7081 tgaagatagc tgaagttgca aactctaaag tatatgtagt tcacttaagc tgtaaagaat
     7141 ccttagagga ggttttaaaa gctaagcaaa gaggtgtgga tgtaatagtt gaaacttgtc
     7201 ctcaatacct tctattaaat gatgaattat atgatttaga tggatttgaa agtgctaagt
     7261 atgtaatgtc accaccttta agaaataaag aaaataatga aatattatgg aatgctattt
     7321 tagataatca aatagacact ataggaacag accattgttc ttttaattat aagggacaga
     7381 aggaacttgg gataaacgat ttcagtaaga taccaaatgg ttctccaggt gtagaacata
     7441 ggatgagtct tttatacaca tatggagtct gtaaaaataa aatatctatc aacaagatgg
     7501 tagaagtaac atcaactaat gcagcaaagt tgtttggaat gtatcctaat aaaggaacta
     7561 tagaaatagg cagtgatgca gatatattag tcttaaatcc aaacaaaaaa tccaaaatag
     7621 aagcaaaaaa acaattacaa aatgtagatt atacacctta tgaagggtat gaagtggatt
     7681 gtcaaataga acatgtttat ttaagaggaa aagaagtagt tagagatgga gaattaattt
     7741 gtaatactcc aagtgggaga tatataaata ggcgtctaac aaagggggct agagaatggt
     7801 agaatttata ttaaatggag agaaagttgt tgcaaaagaa ggcaaaaaac ttttagactt
     7861 ccttagagaa gatatgaata taacttcagt taaaaatgga tgttcagaag gtgcttgtgg
     7921 aacatgtatg gttataatag atggtaaagc tactaaagca tgtgtattta aaactgataa
     7981 attagctggg aaaaacataa caactataga gggattatca gagagagaaa gagatgtttt
     8041 tgcatattct tttgctagtc aaggagctgt acaatgtgga ttttgtattc caggtatggt
     8101 aattagttca aaagcactta tagacgttaa taataatcct actgaagatg atataaagaa
     8161 agctttaaaa ggtaatatat gtagatgtac agggtatgta aaaataatta aagctgtcga
     8221 tttagcggca aagattttta gagaaaatat agatgtgcca aaagtaaact gtaagggtct
     8281 agtaggtgaa aatcttccta gagttgatgc agttggcaaa gcacttggat attctgaata
     8341 tgtagatgat atgagaattg agggtatgat ttatggttca gcagttagag ctaagtatcc
     8401 tagagcttta gttaaaaaaa tagatataga agaagcaaaa gcttatccag gagttgttgc
     8461 agttctaaca gctaaagata ttccaggaac tataaaggta gggcacttaa agaaggattg
     8521 ggatacttta ataccagaag gtgaaataac tagatactta ggagatggaa tagttttagt
     8581 agcagcagaa actagagaag cgttagaaga ggccaaaaag ctagttaaga tagattatga
     8641 ggaattaaca ccattaagta ctacagcaga tgcacttaga gaagatgctc caaagataca
     8701 tgagacaggg aatatacttg ttaaggaaca tttagtaaga ggaaacgcta aagaaaagat
     8761 agaaaattca aaatatgttg taactaaaag atatactaca cctgctacag aacacgcatt
     8821 tttagagcct gaatgtgcag tagctggtcc ttatgaagat gatggagtaa taatctattc
     8881 gacagaccaa ggggtgtttg ccactcaaca tgaatgtgca gatatgttag ggttaccata
     8941 tgagaaggta agagttataa acaaaatggt aggaggaggg tttggtggaa aagaagacat
     9001 gagtgttcaa caccatgcag ccttacttgc ataccataca aagagatttg taaaagtaca
     9061 gttaacaaga aaagaaagta ttattgttca tccaaaacga catgccacag aaatggaatt
     9121 tacgacagca tgtgatgaaa atggatactt aacgggtatg aaggcaacga taatatctga
     9181 cacaggtgca tatgcctctc ttggaggacc agtgctacaa agactgtgta ctcatgcagc
     9241 aggaccatac aattatcaag atattgatat aacaggaaca gcagtatata ctaataaccc
     9301 tcctggagga gcatttagag gatttggagt tacacagagt tgttttgcaa ctgaatgtaa
     9361 tctaaattta cttgctgaaa tggttggaat atctccttgg gagataagat ataaaaatgc
     9421 aataagacct gggcaagttt taccaaatgg tcaatttgca gatgaaggaa cagcaatggc
     9481 agagacacta gaagctgtaa aagaagagta tgaaaagcat ccacgtgcag gtatagcttg
     9541 tgctatgaaa aatagtgggg ttggagttgg tatacctgat gttggaagat gtagattggt
     9601 gataaaagat ggcaaagttc acataagaac aagtgcttct tgtataggtc aagggcttgg
     9661 tactgttatg actcaagtag tttgtgaaac tgctaaccta cttcctgaaa atatagttca
     9721 tgaagttcca gatactcatt taacaccaga ctctggtaat actacggctt caagacagac
     9781 agtatttacg ggagaagcta ctaaggttgc atcaaataag ttaaaagaag ctttagactc
     9841 tggcaaaact ttacttgatt tagagggaga agagttttat ggagaatatg aaagtattac
     9901 agataaaatg ggttgtgaca aagaaaatcc agtaagtcat gttgcttatg gatatgcaac
     9961 acaagttgta attctggatg aaaatggaaa actagaaaaa gtagtagcag cacatgatgt
    10021 tggaagagct ataaatccaa tcagtttaga aggtcaaata gaaggtggag tagttatggg
    10081 tcttggatat gctctaaccg aagattaccc agtagttaac tctattccta cagctaagtt
    10141 tggtacatta ggtttattta aatctacaga tataccagaa atacaagctt taatagttga
    10201 aaagaacaaa gatttattgg cttatggggc aaaaggtgta ggagaaattt gtacagttcc
    10261 tactgcacca gcagtacaaa atgcctatta tgtatttgat aaagaattta gaactgagtt
    10321 accactacaa aatactccat atagtaaaaa aaagtaacaa aaaaaagaaa tattaaataa
    10381 aaaaatagat gaaattgtaa ataaaaaaaa cccttttgca taaggtatat tttaaatgat
    10441 agaatataca tatacaggag ggtttttctt ttataaaata agtttaataa aattgagagg
    10501 tgagcagaat gaattttaat aatagtctag aattaactca gtctcagaag ctaataatga
    10561 ctacacaact taagcaatca ttatcaatat taaatatgag taagttagag ttagaagaag
    10621 agataaaaag agaagcagag aataacccat tagttgaagt cgagaaaagt ggggagataa
    10681 attgggaaga gtatataaaa gacatggata ggtcaagacg tttagataga acagagataa
    10741 gctataatcc tgataatgaa gttaatctag aaaatttagt taaatattcg tcaaatttat
    10801 atgaagattt aaaatttcag ataagcctgt ataaacttac agacaaagaa ttggaagtct
    10861 gtgagtatat aattgatagt ttagatgagg atggatattt aagaactgag gaaaaagtaa
    10921 ttgttgatac cttaaagata gatgaagaac tttttgaaaa atgtttaatt agtgttcagc
    10981 agttggaacc tagtggagta ggggcaagaa gtctttcaga atgtctgatg atacaaatgg
    11041 ctagtttagg aatatataat gaaattttag aggaaatcgt tacaaaagac ttaaatttaa
    11101 ttgcaaataa taaatacaaa gagataagta aaaagtacaa tatgtcatta caaaaatgtg
    11161 ttgaactaat aaatataatt aagacattag accccaaacc aggaagaact tgttcagtag
    11221 agaaaagtgt atacattcaa cctgatgtaa cagtagaaaa aattgatgat gaatttattg
    11281 tatatttaaa tgagaaagat tcttatcaaa taagaatcaa tagttattat aaagacatat
    11341 taaaaaattc acagtctgat gaaagtgcaa aagaatttat aaaagaaaga ctaaattcag
    11401 caacaggact tatgaaaaat atagagagta ggaaaactac agtacttaag attgcagaag
    11461 agatagtaaa agctcaagat gaatttttga gaaaagggac aaaatatata aaacctttga
    11521 aaatgaaaga catagcagaa aaattagaat ttcatgaatc tactataagt agaggtgtaa
    11581 atggtaaata tatgctaaca ccttttggcg tatatgaatt taggtacttt ttcagtagcg
    11641 ccattgagac tgagaataat gaaatggcat ctagtacaag cataaaaaaa attataaagg
    11701 aaacaataaa agacgaaaat aaaaagaaac ctttaagtga tgaccatata tctaagttat
    11761 taaaagaaaa aggaatcaat gttgcaagaa ggacagttgc caaatatcgt gaagaattag
    11821 gaatcccatc ttcaagtaag agaaaagaat actaataagt aaaagacaaa tatcagtatg
    11881 gtaaggggaa aaggctaatt aagagatgaa tgtagattgg gctaaaaatt ttataaagta
    11941 aaataatata atatgaaaaa gtattaaaat gctataaggt attaaaaaac tggggaacat
    12001 taaaacatta agatagcaaa gagcataaaa aactaaagaa gattaaaaca ttaaagaaca
    12061 ttagagcttt gaggaatatt agaactttaa agaatattaa aatttataaa atataaaaat
    12121 actaaaaaga attgaaaaac tggggaacat taaaatattg taaaatgcta aaaaactaga
    12181 aaacataatt aaataagtgc ttataaagaa tgattaaatt aaataagtgt ttgtaaagaa
    12241 taattagata ttagaaaaag aagaatacct agataaataa actattatta aatttaataa
    12301 tcacaaaagg aaaacacgta gggtataaat aaaaatctta actagataaa agtaaactta
    12361 gttgtagata aaaataacta gaaataaaat tatttatagt aataaatatt agaatgaaaa
    12421 tataaaaaaa tatatataaa aagccttata taaaaagaaa aaatactgtg atttgaaaat
    12481 ggtggagaaa tattttataa aataaaaaaa taaaaaagtt tttgaaaaac tattgaaatc
    12541 tatacgcaaa tcctataaaa taaaaatatc ttgtgggact taaataaaca ctagggacaa
    12601 aaaaagtccc gaaaggaaag caataaggag tatgttatga agaacttatt agaaattcaa
    12661 aagaaattga ttccacaggc aattgaactt atggaaagaa gatactctat tttaagacaa
    12721 atatctttaa gtgaaccaat aggtaggaga acattatcaa atgtattaga gattagtgaa
    12781 agaataatca ggtcagaaac tgagttttta aaagaacaag gacttataga cgtagctgta
    12841 tctgggatga ctatcactaa agaaggttct gatttgttag ataaacttaa ggacatcatg
    12901 agtgacatca tgggattgtc taagttacaa gatagagtca gagaaaagct tggaataaaa
    12961 agggtaatat tagttcctgg aagctgtgat gaaaatggaa gtttactaaa agatgtaact
    13021 agatatggat gcgaatattt cttaggcatt ttaaaagatg gagatatcgt ttcaataaca
    13081 ggaggaagca ctatgttgga gttttcaaac gttattaaaa ctgataagag atatccaaac
    13141 tctacaatag ttccagctag aggaagtatg ggaactgatg tagagatgca atctaacaat
    13201 atagttgctt caataagtaa gaaattacat tctaattgca aacttttaca tataccagat
    13261 gagttggatg aaagtgcaat gaaaactctt agccaagtgc cagagattaa gacaactttg
    13321 gagtatatta aaagaacaga cattttagtt tttagtatag gtagagcaga tgtcatggca
    13381 aagagaagaa aacttccaga agacaaggtt gatgagatat tatctaaaaa tgcagttgga
    13441 gaagcatttg gatattattt caacaaagat ggagaaatag tttacaaact gaacactgtt
    13501 ggaattgatt tagaaacagt taaacaagta aaagaaacta ttgcaatctt tgcagggact
    13561 gaaaaagtag aagccttatt agctatatca aatatgcata aaaacatggt tcttgtaaca
    13621 gatgaagaaa gtgcttataa gatattgtca ttattataaa agtcaagacc tagcacagag
    13681 ctagaaaaca tacatttact ttataggagg tagcgaaaat ggttaaagta gctataaatg
    13741 gatttggaag aataggaaga ttagcattaa gaaaaatgat ggagcaacaa gataagttcg
    13801 aagttgttgc aataaacgac ttaacagacg ctaaaatgtt agctcattta tttaaatatg
    13861 atacagctca aggaagattt aacggagaaa tagaagttaa agaaggtgct tttgtagtaa
    13921 acggaaaaga aataaaagta acagcagaaa gaaatcctgc tgacctacca tgggctgaat
    13981 taggagtaga tatagtatta gaatgtacag gattctttac atctaaagat aaagctgaag
    14041 ctcatataca agcaggggct aagaaagttg ttatatctgc accagctact ggagatttaa
    14101 aaacaatagt attcaacaca aacagtgaca tattagatgg ttctgaaaca gttatatcag
    14161 gagcttcttg tactactaac tgtttagctc caatggctaa agtattaaat gataaatacg
    14221 gtatagaaaa aggcttaatg actactatac atgcatacac taatgaccaa aatactttag
    14281 atggtcctca tccaaaaggt gatttaagaa gagctagagc tgctgctgga aacatagttc
    14341 caaacactac aggagctgca aaagcaatag gcttagtaat accttcatta aaaggaaaat
    14401 tagatggggc agcacaaaga gtaccagttg taactggttc aataactgaa ttagtttgta
    14461 cattaggaaa aaatgttaca gttgaagaaa taaatgcagc tatgaaagaa gcttcaaacg
    14521 aatctttcgg atatactgaa gaaatgttag tatcttctga cataatcgga ataagctacg
    14581 gttcattatt tgacgctact caaacaaaag ttatggaagt agatggaaaa caattagtta
    14641 aagttgtttc ttggtatgat aatgaaatgt cttatacttc tcaattaata agaactttag
    14701 gatactttgc acaattagca aaatagtcag ttttgagaaa atagaaaagt agattgacaa
    14761 agtccgagtt tgtagtttaa tactacggac tcaggacttt ttttaagaaa aaatatataa
    14821 aatacaccta aataatgtta catactatat ataaaaatat gataatatga tatatttaat
    14881 agggtaaaag tatgtactat attatacttg gcaataaaaa attactttat taaaaggaga
    14941 gatatttatg tcaatgctta acaaaaaaac tatagaagat attgatgtgt gcggaaaaaa
    15001 agtattagta agatgtgact ttaatgtgcc attacaagat ggtgtaatta ctgatgaaaa
    15061 tagattgaac ggagctttac caactattca atatttaatt tctaaagggg caaaagttat
    15121 attatgctct cacttaggaa agccaaaagg agaagctaaa ccagaattat ctttagcacc
    15181 agtagcaaag agattatctg agatgttagg aaaagaagtt gtatttgcag cagacgataa
    15241 tgttgtagga gaaaatgcaa agaaagcaac tgaaaaaatg gaaaacggag atgtagtatt
    15301 attagaaaat actagatata gaaaagaaga aactaaaaac gaagagaatt tctctaaaga
    15361 actagcatca cttgctgaaa tatttgtaaa tgatgcattt ggaactgctc atagagcaca
    15421 ttgctcaaca gttggtgcag gcgagttttt acaagagaga gtttgtggat acttaattca
    15481 aaaagaatta aaattcttag gagaagctgt tgcaaaccct gtaagaccat ttacagctat
    15541 acttggagga gctaaagttt ctgataaatt agctgttata aacgaattat tagaaaaagt
    15601 tgataatcta ataataggtg gaggaatggc ttatacattc ttaaaagctc agggttatga
    15661 agtaggaact tctttacttg aaatagataa agttgaatat gctaaagaaa tgatggaaaa
    15721 agctaagaat aagggtgtta acttattatt accagtagac gttgttatgg cagaccactt
    15781 tgcaccagat gctactccaa tagtaacaga agatgctaat gtaaaagaag attacatggg
    15841 actagatatg ggacctaaga ctatagcaaa ctttgtaaaa actataaaag aatcaaaaac
    15901 tgtagtatgg aatgggccaa tgggagtatt tgaatttgaa aactttgcaa atggtacatt
    15961 atcagtagct agagctatgg cagagttgac tgatgcaact actgtaattg gcggtggaga
    16021 tagtgcagca gcagttaatc aattaggatt tggtgacaag atgactcacg tatcaacagg
    16081 tggaggagca tcactagaat ttttagaagg taaagaatta ccaggtattg cagcattaga
    16141 taataaataa actaatatat agaggagatt gtaaaatgag aaaacctata attgcaggaa
    16201 actggaaaat gcataaaaca ataaaagaag ctttagaatt tgtaaatgaa gttaaagata
    16261 aagtaaattc tgataaagta gaagctgtta tatgtgcacc atttacttta ttaaaggatt
    16321 taaaagaagc tactaagggt acaaatataa agataggtgc tcaaaatatg cactttgaag
    16381 aaaaaggagc atttacagga gaagtttcac ctcttatgtt aaaagaaata gatatggact
    16441 atgttgtaat aggacattca gaaagaagac aatacttcaa tgaaactgat gaaactgtaa
    16501 acaagaaagt tttaaaagca ttagaagtag gaatagaccc aatattatgt gttggagaaa
    16561 ctttagaaca aagagaagct ggaaaaacta aagatgtttg taaagttcaa gttgaaaaag
    16621 ctttagaaaa tgttcttaaa gatgatttag caaaagtagt tgttgcatat gagccaatct
    16681 gggctattgg aactggtaaa actgcaactg ctgaagatgc taatgacgtt atatcttata
    16741 taagagaagt tataaaagga ttatatggag aattagctaa tgaagttaga atacaatacg
    16801 gtggaagtgt taaaccttca aatgtagccg aaataatggg tcaaagtgat atagatggag
    16861 ctttagtagg tggagctagt ttagctagta atgattacct agaccttgtt aatttctaag
    16921 gagtgaaatg atgaaaaaac cagttgcttt aattattatg gacgggtttg gatacaataa
    16981 ggatgttaag ggaaatgcaa ttgctgagtc caaaactcct aatttagata gaataaaaaa
    17041 agagtatcca aacacattga taaatgctag tggtcttgat gttggtctac ctgatggtca
    17101 aatgggaaat tcagaagttg gacacactaa cataggtgca ggtagaatag tatatcaaga
    17161 tttaactaga ataacaaaat ctataaaaga tggtgacttt tttactaata aagttttatg
    17221 tgaagcaatg gataatgcaa aagaaaactc tcttcatgta atgggacttt tgtctgatgg
    17281 aggagtacat tcacatatag accatcttaa ggctataatc aaaatggcaa aagataaagg
    17341 cgtacaaaag gtgtatgttc acgcatttac tgatggtaga gatactgacc ctcaaagtgc
    17401 attagaatat gccaaagaag tacaagctag tatggatgaa attggagtag gtgaatttgc
    17461 tacagtttct ggtagatact acgctatgga tagagataag agatgggaaa gagtagaact
    17521 tgcatacaat gccatggtta gaggtattgg tgaaaaagca aattctattg aggaagctat
    17581 tcaaaactct tatgatgatg gaaaaaatga tgagtttata atgccaacag ttattatgaa
    17641 agatgataaa ccagttggaa gtataaagga aaatgattca attatattct tcaactttag
    17701 accagataga gctagacaaa taactagagc tttagtttgt gaagagtttg atggatttaa
    17761 aagagaagat attaaaaact tctttgtatg cttaacagag tacgatataa ctatagagaa
    17821 tgtgcatata gcatttggac ctcaatcttt agccaacact ctaggtgagt atctagctaa
    17881 aaatggaaaa actcaactta gagctgctga aactgaaaag tatgcacatg taactttctt
    17941 cttcaatggt ggagtagaag agccaaataa aggtgaagaa agactattga taccttctcc
    18001 aaaggttgca acttatgatt taaaaccaga aatgtcagca tatgaattga cagataaagc
    18061 tttagataaa ttaggagaag ataagtttga ctttatagta ttaaactttg caaatcctga
    18121 tatggtaggt cacacaggaa gtatagaagc ggctataaag gctgttgaaa ctgtagatac
    18181 ttgtgtagga agattgatag ataaaatagt agagttaggt ggaagtgcaa taataactgc
    18241 tgaccacgga aatgctgaat atatgttaga cccagaaaca ggaaaaactg taacggctca
    18301 ctctattaat ccagtaccat ttattgtagt tggtcaagaa tatgaaagtg caaaattatt
    18361 ggatggagga agattatctg atatagcacc tactatttta gatatgatga agttagaaaa
    18421 gccagaagaa atgactggtc attcacttat ttcaaaatag tcgattctga taagtagata
    18481 ataatatata aactacaata taaatttaaa aataatgcag tttaggttta ttttgtaaag
    18541 tttagacttt atgacataag gtttaaattt tgtaagttct ggatattgta aggtgtagat
    18601 gaagatatat tttataaaat ttacaagata gacaatttat aaaataaaaa attacaatat
    18661 agataataat gtaaataatg atataaataa ta
//
LOCUS       DAMJWC010000075        17762 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMJWC010000075 DAMJWC010000000
VERSION     DAMJWC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.076"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            498..1358
                     /locus_tag="PC503_003012"
     CDS             498..1358
                     /locus_tag="PC503_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2528978.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKTLNIKASDYLSLTLLDHLEF
                     LLKRCKKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1348..3219
                     /locus_tag="PC503_003013"
     CDS             1348..3219
                     /locus_tag="PC503_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2528979.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQSTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3239..4693
                     /locus_tag="PC503_003014"
     CDS             3239..4693
                     /locus_tag="PC503_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2528980.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYEMPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLGKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5718..6926
                     /locus_tag="PC503_003015"
     CDS             5718..6926
                     /locus_tag="PC503_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528981.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6957..8336
                     /locus_tag="PC503_003016"
     CDS             6957..8336
                     /locus_tag="PC503_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528982.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8442..9632
                     /locus_tag="PC503_003017"
     CDS             8442..9632
                     /locus_tag="PC503_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2528983.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIREETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEVLLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9760..11088)
                     /locus_tag="PC503_003018"
     CDS             complement(9760..11088)
                     /locus_tag="PC503_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528984.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11706..12920)
                     /locus_tag="PC503_003019"
     CDS             complement(11706..12920)
                     /locus_tag="PC503_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2528985.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13346..14062
                     /locus_tag="PC503_003020"
     CDS             13346..14062
                     /locus_tag="PC503_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF2528986.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14197..14823
                     /locus_tag="PC503_003021"
     CDS             14197..14823
                     /locus_tag="PC503_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2528987.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15023..16567)
                     /locus_tag="PC503_003022"
     CDS             complement(15023..16567)
                     /locus_tag="PC503_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2528988.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16593..17234)
                     /locus_tag="PC503_003023"
     CDS             complement(16593..17234)
                     /locus_tag="PC503_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF2528989.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17504..17695
                     /locus_tag="PC503_003024"
                     /pseudo
     CDS             17504..17695
                     /locus_tag="PC503_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         6564 a         2088 c         2930 g         6180 t
ORIGIN      
        1 tcttactagc atttaaatga aactaaattt gaagctttac ctattaatat atcttaatag
       61 tgattaaata aaactaaact taagacttta tatgttaata tatcttaaga atttatttgt
      121 taaaatacag ttcattatat ttaaaagcat tactatgata attcataata gtaaaataga
      181 taatggttca gacaatatta taaatactag tgacggtaaa atagtatcaa tttagtatat
      241 aaaccttgtc agataatcgc ataacagagc ttgtagttat agaataaaaa aatatctagg
      301 aaaccgttga cagatttata tggatagtat aacatataga atatgaaatt aaacaaaaaa
      361 gaattttaat tatggcgacg tagtcataat tttgagtatg ttactgatta gcaggcagaa
      421 ctcaagtata tatgtgaaaa atagagggat actctataca tatatgcttg agttcttttt
      481 attgaaggga ggaatatatg aaaataattc agattttaaa taataatgta gccttagtaa
      541 aaagaggtaa aaatgaaatt attgtatttg ttaaaggaat tggctttaaa aaaagagtgg
      601 gacaagtaat aaatgaaaat gaaatagaga gaacatatat actagattca tacgatatgc
      661 tagaacactt tagttatcta ctacaaaact cagactccaa taatatagtt cttattaatg
      721 aaataattga atatggtgag aaaactttaa atataaaggc aagtgattat ctaagcttaa
      781 ccttactaga ccatttagag tttttactta aaagatgtaa aaagaatcaa tttataaaaa
      841 gtcctttggt atggaatgtt aaaagatttt atccaaagca ttttgaaatt ggaatgcatg
      901 cactaaaatt aattggtgat agtaagggaa ttaatcttcc tgatgatgag gcagtatcaa
      961 tagcacttca ttttgtaaat atggaggtaa ataaagagtc tcatgatagt acaattgtag
     1021 agttgagaac tttagcagat atagtttcta taataaaata tcattttaat gtagagctag
     1081 atgaaacttc aacaaattat atgagattta ctactcatct acagtacttt atccaaagaa
     1141 ttatgtcaga ggaagcttca atagatgaag ataattctat agatttatat aaacaagtaa
     1201 gtcaacttta tccaaagtca tttggaagtg ttcaaaagat aagaaaatat ataaaatcac
     1261 aatttaatgt cgatatatct ataagtgaag aaacttattt aatgttgcat ataaataggg
     1321 tgactcaaag actggaggca aaatcagatg aaatataaag atttaaatga aaatataata
     1381 aaacttatag ggggaaaaga aaatataaag tcggtagcgc attgtgttac tcgtttaaga
     1441 tttactttaa atgataggag tatcgctcaa acagaagaaa ttaaaaaatt aaaaggagta
     1501 attgatgtag tttctaatga tgttgcttat caaattataa taggtactca tgttgtagat
     1561 gtatataacg agtttatgtc tatgataggt ttaagttcaa gtgaatcaag tataaaaagt
     1621 gaaagaaaaa agggaattag aggtatcaaa ggtatattta attccatctt tgtggtagtc
     1681 tcagagacta tgacttcagt aattgaagta ctacttgcag ctggtatact tgcaagtata
     1741 ttagcacttt taaatatgtc tggcatactt cagagtgaca gtcctacata tcaaatatta
     1801 gatacattaa gaagtgctac atttcacttc ttaccagtat taattgcaat agcatcagca
     1861 aaaagactta atgtaaatcc atatatagca gtagtattag cagttacgtt attatcttca
     1921 tcaatagatg gtgtagaagg attaagttta tttggtataa atttacagtc tacaacttat
     1981 gcaaacagtt ttattccaat acttttagga gtatgggcaa tgggaattat aattgaaggt
     2041 ttgaaaaaaa tattacctaa agcactacac tattttttag ttccagtatt atctttaata
     2101 ataactctat cagttacatt aactgtattt ggacctattg gtatgtggat tggtgatgga
     2161 ttaaactatg catgtatgtt tttaattgat acattgggta attggagtgt tgttgcactg
     2221 tatgcagctt tacaaccact cttaatagtc tttggtgcag caaactttac tatgcctata
     2281 tctttaaatt ctgtgacaac attggggtat gacccaattt ttatgggcgc tgcaacaata
     2341 tctgatattg cagtttgtgg tgcaatgttt ggatatttct taaaaactag gaataaagaa
     2401 caaaaacaat tatttggtac agtaagtttt agtgcactta tgggagttac agaaccttca
     2461 gtgtttggtg tgtttatgaa atatagaaga ccatttgtag cagtaatgat aggtggaggt
     2521 ataggtggtt taatagcagg tttagctcaa gttaaaacat atggaatggt ttggggatta
     2581 gctgcattac caacgtatct tgttggagga gaggtatcta actttacatt tatgataata
     2641 agtgtagtag tatcatttgt agcagcaaca gcagcttcct atttactagg aataccttca
     2701 gatgaaaaag aagaagttaa gggtgataat gaaaaagaat tagaactaat aatcaacgag
     2761 aacaattcaa gaactattag tattggaaat gttgcaaaag gtcaggtaat tgcacttggg
     2821 gaagttaatg acaaagcatt ttcctctgga gcattaggta aaggggttgg agttatacct
     2881 agtgaatcaa aatcaactgt tatatctcct gtagatggaa ctataactat agtatttcca
     2941 actaaacatg catatggtat agtgactgat gaaggattag aaatattaat tcatattggg
     3001 atagatactg taaacttaga tggaaaattc tttgaaagtc ttgtaacaca aaatcaaagg
     3061 gttaaaaaag gagatgcttt agcagtattt gaatctgata aaattataga ggaaggcttt
     3121 gattctacta taataactgt agttacaaat actagcgatt atttagatgt aatctcatca
     3181 aatgatgaat cagaagaatt attaactgta atagtataaa ttttaggagg gaaaattcat
     3241 gaatattaaa gatacatttt tctggggagg aagtattgca gcccatcaat gtgaaggttc
     3301 atgggatagt gacaacaaag gacctgcaat tatggatttt gtaactaagg gctcttatga
     3361 aatgccaaga gtaattactg ataaaataga agaaaaattg gattatccat ctcataatgg
     3421 aatagatttt tataatagat ataaagaaga tatagcttta tttaaagaaa tgggatttag
     3481 tgcattaaga atatctatag attggtcaag aatttttcca aatggagatg atgaaaatcc
     3541 taatgaatta gggattaaat actatgaagg tctgatagat acattaatag aaaataatat
     3601 agaacctatt gtaacactat atcattttga attacctatg aatttagtac ataaatatgg
     3661 ttcatggaat aacagaaaac ttatagattt gtatttaaag tacagtgaga ctgtaataag
     3721 aagatttgat gataaggtaa agtactgggt tacatttaat gagatgaacc atattgaccc
     3781 tcaaacagag cactcggata tttttactta tatgatagca ggtattaagt atagtgaaat
     3841 agaaaataag gttcaaacat tggcaaatgt agggtataat atgactttgg cgggtgtaaa
     3901 ggttgcaaag ttggctagag aaatcaatcc caacaataaa gttggatgtg tatttggact
     3961 aaatccaatt tatccataca attgtaatcc tagtaatgtg ttaaatgcat ttttagataa
     4021 tgaccgtgat tattatcaaa ttgatgcaat gtgcaatggg aagtttccac aatataaatt
     4081 aaaagaatat gaaaaaaata atataactat tgaagtgact gatgaagaca aaaaagcatt
     4141 taaagaaggt aagttagatt ttataggact taattattat ttttcaagtg tatctactcc
     4201 aaaagaaaat ttatcaggtg ataaatcttt atttggtggg attcaaaatc catatttgga
     4261 acaaagtaag tgggggtggg caatagaccc tataggttta agatttacct tgaactatat
     4321 ttacagaaag tatcaattac ctatcttaat tacagaaaat ggtttagggg catatgataa
     4381 aatcgaagaa gatggaacta taaatgatga ttatagaatt gaatatttag gtaagcatct
     4441 atctcaaatg aagtctgcaa ttgaagaaga taatgttgaa tgttttggat atttgatgtg
     4501 gggaccaatt gatttagtca gtgcaactac aggtcagatg agtaagagat atggatttat
     4561 ctatgttgac ttagatgatg aaggcaaagg aagttttaag agatataaga aaaaatcatt
     4621 tgattggtac aaagaagtaa taaaatctaa tggagaagtt ttagattttt ctacggatat
     4681 agtagtaggg taggaataag ataaatagaa gttaggaact aatgttaatt agtgtctagt
     4741 aaagcattta aaatagagta tagggtcttt aaagtaaagt gtgtattctt cttaaaagta
     4801 atggcaacta aaattactat aaaaaggaga atacacattt tttatgttta tacttaagta
     4861 aatatttaga catattcata gtataattta ctcattatat aaaaatagta tgatttactc
     4921 actatataac tttataaatt ttctggaaaa atgtcagaat atattgacaa agaaaagatt
     4981 taaaattata atctatatta agaatagttt gacaatataa aaacaagtat ttttataaat
     5041 agtgaaatta tttttattgt caatttaaga ataatttagg actactataa agataaaggt
     5101 atagatgtca ttatatgata aattatactt gtatagaaag aattttaaag tatggcttat
     5161 cattgattta atataataaa taatttttgt ttctagtaat agttcctagg aataagatat
     5221 ctaaattcgt ttagaaatag tctaatttac aaaggagggg atgcactaat agataaaatt
     5281 tctatataaa gaagacttaa agtgaagtat attctgataa tattggttta atgggtatat
     5341 tattatttcg ttttagatat tttaagaata atttaagacg tttataaaaa tgtattctat
     5401 atctaatatt taaataaata taagtcttcc aacatgtata ctaatataga gagtagttga
     5461 agtacaattc taactcgtaa aattatgtag aaagtaaaaa tcaaaaagaa atctagtaag
     5521 ttgataacta tagttaatat ttagagagtt aactctagtt atatttattt agatatttta
     5581 ggaataattt aggacgtata taatatcatc aaaaaatatc aagctatacc atatgtagtt
     5641 aagaataact gcataatata cattttataa ttattgtttt attgataaaa aattattata
     5701 tttaggagga aacaacaatg gaaaattttt ggaatccact tacttgcttt actgtatgtg
     5761 taatgattta tgcttttagt gagtttttat ctaagaaaac aaaaggtgca atttcaacat
     5821 tgttatttgt atgtattata tttttactag gattttggac aaatatttta ccaaaagaca
     5881 ttacaggagc atcagggata ttagctgcaa tgagcaactt tggtatagct ttattaataa
     5941 ctaacttagg aacacttata aatcttgaag acttatgtca tgaatggaaa acggttgtaa
     6001 ttgcattagt aggtattgta ggaataggag ttggctgttt aacagtgggt agtatgttat
     6061 ttggcagaga gtatgcttta atagcagcac ctccaatagc aggttctact gttgctggga
     6121 ttatcgtaac aactgttgca gaagctgcaa atagacctga acttgctgca tttgtaattc
     6181 tagtattatc atttcaaaag ttctttggta ttccgataac tacatattgt ataaataaag
     6241 aattaaaatt taaaagagat aacggggatt ttttgaaaga tgagtcaaaa agtaatttta
     6301 aacttccaag tatgagaatt tttaaagaag atttaggtaa aaaatcatct actctagtgt
     6361 atcttgcaaa gctttcattt gttgctatga ttggtaattt tgtaggattg gctactttaa
     6421 taccaggatt tacccctgca aactattatt taaatcctaa tatagcatgt ttgttagtag
     6481 ggttgatttt tacacgaata ggttttttag aaaaaggaat tttagataaa tctcaatcta
     6541 atggaattat aatgtttggt tgtatgttga tgttacctgg aggacttgct aaggtaactc
     6601 caacagcatt gtttgggatg attgttccaa ctataggaat acttgttgta ggttctgtat
     6661 ttataatatt atttactgca attgtaggaa aactattggg atattctcca agaatgtcag
     6721 ctgcaattgg tgtaacttgt atgctagctt atcctgcaac acagataatt tccaacgaag
     6781 gtattgatgc tatggaagga actgaagaag aaaaacaaag ggcaacagat tatttattac
     6841 caaagatgat tataggagga tttgttactg taaccattgc atcagtggca tttgctagta
     6901 taataggtcc aattatattt ggttgatagt aaatatactt ataggaggaa taggaaatga
     6961 taggaagtat atctataaat gagatagata aaaaaagatt caaacttgat gatttaagta
     7021 agaaaatatg ggaaaatcca gaaaaagcat ttaaagaatt taaagcatgt gaaaatacag
     7081 caaactttct aagaagtgaa ggatttgatg tggaagtagg tgtaggaggt ttagccacgg
     7141 ctattagagc tagttttggt tcaggtaaac cagttatagg ttttatggga gaatttgatg
     7201 cattacctgg tttaaatcaa aaagtttcaa caaagcaaga agcatttgaa ttgggtgcat
     7261 atggtcatgg atgtgggcat aatttattat gtacagcaca tgtaggggca gtagtagggc
     7321 ttaaaagaga gatgatagaa aataacttaa gtgggactat agtattttat gcatgtccag
     7381 gagaagaaca attaacaggt aaaggattta tggctagagg tggagcgttt gaagggttag
     7441 acttagctat aaattttcat ccaaataaaa ttagtgaagc tacaattggt acttcaacag
     7501 ctgttaactc tgtaaagttt cactttaagg gaaagactgc acatgcaggg tcagaccctc
     7561 aaaatggaag aagtgcacta gatgctgtgg aacttactaa tgtgggagct aattatttga
     7621 gagaacatgt tacttctgat gtaaggattc attatacaat tacagatgga ggagtagcac
     7681 ccaacatagt tcctgataaa gcatcagtat ggtattatac aagagcttta agtagagaag
     7741 ctgtagaaag tacatatgaa agacttgtaa aggtagcaaa aggagctgca atgatgactg
     7801 aaactgaagt tgaagtagag tttttaggag ggtgttataa tactttaaac aatcatgttt
     7861 tagcaaatct tgtatcagaa tgtatgaatg agattaaaca agagccttgg actcgagagg
     7921 aattggattt tgcagctgaa ttagatagac aaagcccaca acaatataag gctatgataa
     7981 gtaaatataa tttgccagaa ggaactcatc tatattatgg tggaggaaat gttacaaact
     8041 ttaatagtta tggctctact gatattggag atgtaatgca tatagttccg acagcatact
     8101 tttttacagg gtgtacgaat ctaggagcac caggtcatag ctggcagttt acatcttgtg
     8161 caggaagttc tataggagaa aaaggtatga tatatgcatc aaagattatg gctatgtttg
     8221 gagctaaaat attaaataat ccagagatag ctaaaaaggc aaaagaagaa tttgataaat
     8281 ctatgaatgg taaaacatat aaatgtccta ttccagatga tattccaact ccttaaaaag
     8341 acatgaaatt taatatataa aattataatt tttatatcag catcatttca ttactaaaag
     8401 aaagtgagat tttgctgact atctgattag gaggaaggaa tatgaaaaat ttttttaaag
     8461 aagcgcagtc aatagaaggg gaaattatta gatggagaag gtatttacat gaaaatcccg
     8521 aaattggttg caatctaccg aaaacagtaa cctttgttac cagtacttta gaaaaaatgg
     8581 gatattctcc gaaattgacg tctaataatg gaatagtagc tgttttagac agtgaaaatg
     8641 gtggaaagac cttattatta agggcagata tggatgcact tcctattagg gaggagacgg
     8701 atttaccttt taaaagtaag aataaagatg catctcatag ttgtggacac gataatcaca
     8761 cagcaatgct cttaggagca gctaaaatac ttatggataa taagcactta cttaaaggta
     8821 gagtaaagtt tgtatttgaa ccagatgaag agactaccag aggtgcaaaa tcaatgattg
     8881 atgatggtat attagaaaat cctcaggtcg atgcagctat ggcatttcac agtatggtgg
     8941 gtaaatttct taacacaggt caagtagctt attcacgtgg tccagctatg gcatctgcgg
     9001 atatatttga aataacagta gaaggaaaag caactcatgg agcaagccct gaatttggag
     9061 tggacccaat aaacataatg tcgcatatac aaatagcatt aaacactata ctttcaagag
     9121 aaaaacctca gaaagagcct gtagttttaa ctattggtat gtttaatgca ggaaacgtac
     9181 caaatgctat accaaataaa gcatctatgt caggaacttt aagaacattt gaccaatttg
     9241 ttagagaaaa attaaaaaat agaattattg aaatatctac aggaatagct aaatcatttg
     9301 gaggaaatgc taaagtggag tttaaaatgg ggactcctgc agttataaat gatttggatg
     9361 taggagatga gattgtatct tatgttaaag aagttatagg aaatgaaaat gtaatagact
     9421 ttccatctgc aatgggttca gaagattttt cagaggtttt actaagggtt ccaggagtat
     9481 ttttatggat tggaatggga agtattagtc agggatataa ttttggtatg cataatccta
     9541 aagcaatttt taatgaagag ggattagttt atggttcagc tttatttgct cattgtgcag
     9601 taaaatggtt agaaaataat tttagtagat aataacataa aatattatta aatatcataa
     9661 aaggtatatc ttaaaaagat gcaaagatat accttttaga aagtcatata taattttact
     9721 taatattaga tgataaaata tttttatgca ttttggattt taatatttat tttctgatat
     9781 aaataatttg tatacccttt caggtctgcc ttttgttgag ttttgttttt catataatat
     9841 agtagcgttt ccagacttta agagactact tagaaatcta ttagcagttc taactgttac
     9901 atttaaacat gaagataatt ccttaggagt aacttcatct ctttgtagaa tttcagtaac
     9961 agatataatc ttttgaatag taagagtaga caatttagaa cttttggcaa ttgtatttat
    10021 atgtggagtt actttatttg aaacagtaag taacttatca cacagtaaag gtcctattgt
    10081 ctcataattt tcgttaacta agaaactgta atttaaagga tttattttag attccttatt
    10141 agcacttatg gcactagaca tagcttgctt tatatcatta ccaattccat atccaataca
    10201 tactttaata tttgtactat tttcaataga ttcttttata taacatgcag taaaattttt
    10261 agttaatgat ttaatcgttt cacatttagt gaaaatttta aaagaattac tatttttttc
    10321 aattataaaa tcggttaatt tatctttttt aatactattt aatattttat aaacttggtc
    10381 tagagtagag tcatcataat ttgtatcttt aactgttata tatattacac ttggttgatt
    10441 tcccttcatt ctatgtaaat gaatatcttt tattaagtta ttaaaagtat tttttaataa
    10501 atctatatca gggtatatga aatgaaagtt tactcctgca ttttgtaaca taggaacaat
    10561 actactaaaa cgagtagtag aaaaatcgat tttcccttca ttccatagat taatatgttt
    10621 ttttgcaatc tttttttcaa gttttgctat gtcagataaa ctcattttag atgcattttc
    10681 atcaatacta tccattaagt ctccaaatgt gccatttgat aaataatatg atatatcttt
    10741 tggattatct gcccagtctg ttaagtcaaa gtatgctctg gaaaaatcta atgtattata
    10801 tttaaagata agctttagaa acatatcata gtaactttgt aagtcagtac caaaatcaac
    10861 tagaggtttt ttaatagttc cagccttttt tgtaatagct tttttgggga tggggccact
    10921 aactgcaaat ccatcaaacc tatcttctat ttctaaatat aaatctccaa catgagaaaa
    10981 atctctatag atatatattt caatttctgc attaatattt aactttttta tagaattatc
    11041 tacaaactct tttaaaaatt cggttgttat gactgctatt ttcatcatag attacttcct
    11101 tttcaattat tataattatt ttatattaaa tattacatta atctattgtt ctagttaaaa
    11161 tcgtatttca attaaattca attaaaataa ataactcttt ataaaaagca attatttagg
    11221 tagaggaata tttgctaact ttaatagtct ttgttaactt taattttatt taagttatta
    11281 tagtcttact aattttataa ttgtagattt aactacttta tgttctttta ttgtttatgt
    11341 agttgattta gaagttattt taaccattta ttttaattga agttgtttga cttttaaatc
    11401 ctttgtgtaa tctttgtttt tctagccatg ataaaagtat ttctatttgt atcactatat
    11461 ataataatat catgacaaaa tatttattgt ctaactaatt ataatctatc caaaatgaaa
    11521 atgggtgtga gatattatta caacaaattg tattagtatt aaaaagatta aaaaattaaa
    11581 aaactaaaca gttaaataat taaacgatta agtgactgtc atataacaat ttataatttt
    11641 atttaacagc cacttaggta tttaagagcg atagaattga gtgtatatca aattataata
    11701 atttcctagt aaataattga aaaataaggt agtccatttt tatatttgat atctggttta
    11761 ccttgaataa gtggatatag ataatttagg gcttcatcag ttatataatt acattcttca
    11821 tttatccact ctttaggaaa atattttgtc ttgttagcta ttttagaaat atcagtatga
    11881 ctaacttcat acttataagg attattgcat gttctattaa tgatagccat aactcctgta
    11941 tatccttttt tagatagttc tatcccatat gcaccaactt cagctgcttg ttttaaatca
    12001 gtatctgaag ctaaatgcat agcacatctt tgtattacac caagttctaa ggtttttact
    12061 cttgttgtaa ttgatgatga tactataaga ttctttagat agttgcttac tccacctaat
    12121 tgggaatgac caaatttatc atgagcagaa gttttttgtt cgcatataaa gttgccgtat
    12181 ttatccctta taccttctga tgcaactata taagccttat ttttttcttt aaatattttt
    12241 ctaacatctt ctataaactt atcttcatag aaatcaattt ctggaaggta tattaaatca
    12301 acaagtggag tatcattaag tctagctagt gaagaagaag ctgctaacca tccagtatct
    12361 ctacccatag tttctactat aaatatacca ttatttttgt atatagaaaa atctaagtat
    12421 gtttccatta ttagtgtaga aataagcttt gcagcagaac caaatccagg acagttgtca
    12481 gttcctaata aatcattatc tattgtttta ggaataccta taaattttat tttacaagta
    12541 gtgtttttgc agtattgaga aaatttcatc actgtgtcca tagaatcatt tccgcctata
    12601 taaaataatg tatctatttt atattcatct agtatattta taactctatc ataatcataa
    12661 gaatttattt tataatcagc cagtttgtat ctacaagaac caagaccaga cgaaggtgtt
    12721 tgctttaaat ttaatacatt atctttgttt aaggagtctg aatctattat atttttgttt
    12781 aatatacctt caatcccatt gataccaaaa tatactttat caaagtattt agtttctaaa
    12841 tttttttcat aaataccaac tgcagaagca ttgataacag ctgtagggcc tccagattgg
    12901 gcaataatac agtttctcat tttacatctc cctttcatta atattgttat gaatggtact
    12961 ttttatcgag taaatttata tttatagtct gattatatat taaatgaact agctatatca
    13021 attgagttag tatagacaat aaatgccata agaatgtggt aaaaaactaa ctttttatat
    13081 acaattaatg tctataattt accacaatat aaaggtactt ttaaggagta gtcaaagtgt
    13141 tgtgaaaaaa aatatatcag tgtaatatta atttacaaag caaaataagt tcacagttaa
    13201 caaaagcaga ataagttcat aaaagaaata tatacagcaa taaaagtaat gctaaataaa
    13261 agtaatactg gattaaaaaa tattaaaaaa atattaaaaa ctaatattta atactaatta
    13321 aagtaaaata tggaggtata caaatatgaa acacataaaa atagcagcag gattagcaca
    13381 tgtaaattac ggtcatatat cagccgtagt taaagaagca atggatgcag gtgtagacta
    13441 cgtacattca gatgcagcag atatgcatga cttaaaaaat atgcaactta tgggtggtca
    13501 tcaaataata gaagcaataa gaccggtgac agataaacca atagaatgcc atatatacac
    13561 aagagattgt gatagattat ttatagaaaa aatagcagca gcaggatgta acttgttgat
    13621 aataccagca gaacattttt taggtgctcc tcttgcatac ataataaatt actgtagaga
    13681 atttggtatg aaagtaggat taacaattgg atgttacaca ccactatgtt ttgttgatga
    13741 agctatatat gatatagata gattgcaaat agtcgttcat ggtgttgatg aaactgatgg
    13801 aaaagataac tggggatgga gaaagagtgc tgttgattta gtaaaaagag ctagaaaaat
    13861 gatagacgaa aagaatccta agtgtgaatt agcaatagat ggtggactaa gagcagacaa
    13921 tatggagcca ttaatagaat gtaatccaga cgttgtaata ttatcttcag caatattcaa
    13981 ggataaagat ggtataacag caggtgttaa gaattgtaga aaagctatag atgaagcagc
    14041 tacaaagttt ggtttagaat aagataataa actatgataa aagagatgct ttcttaatgt
    14101 tttaaggaag cattaatttt atgaaaaact acaggaagct agactaattt aattgatttt
    14161 ttatactgaa acaatataat cataggaggt tattaaatga aaaaagaaat gataaaagat
    14221 tatttactga taacaatatc agcattttta atggcattag cagttaattt tttctttgca
    14281 gaacatacat tagctccagg agggataaca ggattatcag tcgtacttag cacattctta
    14341 tcaatgcctg ttgagaatat atcattagga atatctatgc cacttttagt aatgggatta
    14401 ttatttttag ggaaaggttt tggaataaaa acattatata taactcttat gggcccatta
    14461 ttcttaaaag taataccaca aactcacata actgacaatc tattagtagc aggagtgata
    14521 ggtgggttat tggtaggaac tgctataggg atagcaataa taaggggctg tagtactggt
    14581 ggaactgatt tagttgcaat gcttattaat aaggtaatta agtttctgaa gttgccagtt
    14641 atattattta tgctagatgg atttataata gtagcgtctg gaataataag taagaatttt
    14701 atgatatcta tatattcatt gatatcttta ttactcataa taaaaacaat aggatttgta
    14761 actacaaagt ttggtaagaa tactgaagaa attaataata taaataatgc ttgtgctcaa
    14821 taaaaataat aaaatttact ttaaatataa aagtttaaaa aatataaaag cttaaataaa
    14881 aagattaaat ataaaaaatg aaggtgtctc aaaatgaatt ttttagttca tgaggcactt
    14941 tttctatgaa atcaaatata tttttatcat ttggacaatg aaaaataggt ttatctctat
    15001 gttgagacaa gcctattttt gtttatttat aagataatat tttatttttt tcagaatata
    15061 gtttttttat aattgtacta agtctagaaa tatcattctt acttaaaaga gcatttatat
    15121 ttatcagttc agcattatgt tcaaagtcta caggagcagt ggttagtatt aagtccacat
    15181 catcaaagtt cgtaaatgaa atagaagata gaggtataga tttaactata ttaatctgat
    15241 taaattcaaa acttaacttt tggactaata aattagatac accatcacta cagtgacata
    15301 ttaaaatagt atttagggga gatttgcttc tatctattgc tgatattaaa tataaagcaa
    15361 gatatcctat ttcgtcatca ttgacttcat aattcatcaa ctgtttgata acagtattag
    15421 actctttagc agccttataa gtgtaaggaa atgttctctt tatatcattt aatatgggat
    15481 ttgtaatagt aaacccatag tttattctgt gtagaactga tttaaggtga ttagcaagag
    15541 actttattaa tattaaatca tcctttaagt ttaaatttag tatacttccc caatgaacag
    15601 ctattgcttc agatagatta tactctgtaa tttcttcatt tttaagaggt tcaagagtag
    15661 tagttttctt tattgattta agtaatcctt ctatatgaag aaggatataa cagacctctt
    15721 catcaataaa ttctacgtca aaagcttcac ttaggttagc acataaaatt tttgattttt
    15781 caaagtattc atgttctaat aattctctaa aaaaaccttc agataagtta atatatcttt
    15841 taattgaaat tcttttaata catatagcta tatgtattaa gaagtttata taatactcat
    15901 cactaaggtt acttttttct acttgtaagg tgtgtagagt gatttgagat aatttctcaa
    15961 aatcatagtt aaatagctcc ttaaatattt ttgttgatgg ggtatctttg cattcattag
    16021 atttcgagaa taatatttct ttaagttcag tataactttt attaaccgta gcaagttcaa
    16081 aaattgcttt tcgaatatct ttctcttttc cctctaaata tactccatta ttggtttttc
    16141 taactagagt cactttaaag ttttgcaaaa aattttgaat aactaccaag tctttatgca
    16201 cagtagctct actaacatgt agttcattgc aaatatcacg aatcctaaac ttagaatttt
    16261 taataaataa tttacttaga atataccttt ttctatcttc aggagagtat gcatatatac
    16321 aatttgattt atcattgata tctctaataa ctttaagttt tatatcttca ttacctagaa
    16381 taataacccc tgaaccagtt tttttatcta gggataaatt aaactctaaa agccattcat
    16441 ctaaaataac aaggtcatta cgaatagttt tattactaac ttttaattct tcggcaatag
    16501 tatctacagt aatatagtct gagctgttga gtaataattc agcaatatct aataatcttt
    16561 tgttcaatgc aaaccctcct aaatcttagt tactatttat taaccttgga ccaatctctt
    16621 tcaaaagtat tggcaccatc tattgtaagc tggttaaaag aagctttttt aaataaatca
    16681 tatgttacag ctgcataatc acatccacaa agagatgctt gagttaagtg gaatacattt
    16741 ttaatagaag ctgcaacaac tttagtatta tatccattta ttgatataag gttacatatt
    16801 tctgtaaggt tttttatacc atcattccca ttttcatcat ttctacctat aaaagggaat
    16861 aggtaatcag cacctgcatt tatagctaat gatgcttgat ttacattgaa aatcaaggta
    16921 catgcagttt ttacaccttt actatttaat atgtttataa gttctaagcc aacttcagag
    16981 aaatttattt ttattatagt gtttttattt atatttaata tcttatcaca tgaattaatt
    17041 aattcgtata aattatttcc aatgacttca gcagttaata tttctggatt taaattagca
    17101 catgtctcaa taaattcatg gaagtttact ttctctttaa gatacataga tggattagcg
    17161 gttattccct taaatccata ctttagacac ttttgaattt catcaagatt agcactgtct
    17221 atcaaatatt tcataattta attctccttt aagctatttg tcataaaaaa gtgtatatac
    17281 tctattttta ttattaagtc aattatacaa taagattgat tataaaatta taacatgggt
    17341 acttaataaa atttacataa tgatatggta ataataaaac attgattgtc taataattac
    17401 cataagcttt agtaaataag agttaacagt gaaggtattg ccttaaaaat cctatgatat
    17461 gtataatttg aatatgaagg caataattta agggaggaaa aatatgatta acttttatca
    17521 accatcaaga ataaattttg gacaaggaac tttaagtgaa ttacctagaa taataggaaa
    17581 atatggaaag aaatgtttgt tagttactac tccaaatgta gagccattag acaagttata
    17641 taaaagagtt acattgaatt taatagaaaa aggtatagaa gttgtacact ttgattaaaa
    17701 aatagctacg cacactcgtg actttagtca tgagttaata gctaaaatag tcagcatata
    17761 gg
//
LOCUS       DAMJWC010000076        17693 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMJWC010000076 DAMJWC010000000
VERSION     DAMJWC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17693
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.077"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            470..1378
                     /gene="trxB"
                     /locus_tag="PC503_003025"
     CDS             470..1378
                     /gene="trxB"
                     /locus_tag="PC503_003025"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2528990.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCITSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1468..3291)
                     /gene="typA"
                     /locus_tag="PC503_003026"
     CDS             complement(1468..3291)
                     /gene="typA"
                     /locus_tag="PC503_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF2528991.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3503..3745
                     /locus_tag="PC503_003027"
     CDS             3503..3745
                     /locus_tag="PC503_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528992.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            3893..4084
                     /locus_tag="PC503_003028"
     CDS             3893..4084
                     /locus_tag="PC503_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF2528993.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4368..6869
                     /locus_tag="PC503_003029"
     CDS             4368..6869
                     /locus_tag="PC503_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2528994.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVKNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7029..7697
                     /locus_tag="PC503_003030"
     CDS             7029..7697
                     /locus_tag="PC503_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2528995.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7681..8958
                     /locus_tag="PC503_003031"
     CDS             7681..8958
                     /locus_tag="PC503_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2528996.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9359..9580
                     /locus_tag="PC503_003032"
     CDS             9359..9580
                     /locus_tag="PC503_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2528997.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(9869..10633)
                     /locus_tag="PC503_003033"
     CDS             complement(9869..10633)
                     /locus_tag="PC503_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2528998.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            10907..11581
                     /gene="fsa"
                     /locus_tag="PC503_003034"
     CDS             10907..11581
                     /gene="fsa"
                     /locus_tag="PC503_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2528999.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVGKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(11703..13097)
                     /locus_tag="PC503_003035"
     CDS             complement(11703..13097)
                     /locus_tag="PC503_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF2529000.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(13175..14521)
                     /locus_tag="PC503_003036"
     CDS             complement(13175..14521)
                     /locus_tag="PC503_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2529001.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      14771..14873
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            14967..16343
                     /locus_tag="PC503_003037"
     CDS             14967..16343
                     /locus_tag="PC503_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2529002.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(16457..17602)
                     /locus_tag="PC503_003038"
     CDS             complement(16457..17602)
                     /locus_tag="PC503_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2529003.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
BASE COUNT         6737 a         2168 c         2763 g         6025 t
ORIGIN      
        1 tatttaaact attaatcata attggttcaa caaaagtata tagttaataa tgtttaattt
       61 gaagaaattg ttagtgtgaa attacatata tattcaaatt aaattcataa atatttcaca
      121 taataatagt atactgtaaa caaaaggagg tattaaatat gggaatagta cttataacag
      181 cagcattagt tttggttatg tatggacttt caattctatc atatatatca gaaagcaata
      241 tattagaaga cactgtaaat gataaccaat aaggttttga attatataaa taagtgagaa
      301 ctgtaaataa aagttaattt ttatttgcag tttttttata tatatgtaaa ataaagttaa
      361 ttaataaaaa ataatgtttt gtttatagta tatatggata ataatagtaa agtataagaa
      421 tgatgagaat aatatataag aaataataat ataaagagag gtaaacgtta tggtagatat
      481 cattgtaatt ggtgctggac cagcaggttt aacttcagca atttatgcta tgagagcagg
      541 gttaagcgtt acagtatttg aaaaaaatat ttatggaggt caagttgcaa gtacctctga
      601 ggtagaaaat tatccagcag ttcaaaagat ttctggggta gaattttcta ataatatata
      661 caatcaagca gttgctcaag gtgttgatat tcagtttgat gaggttgaag agataaattt
      721 agagggaaaa gtaaaggttg taaaaacttc ttcaggtgaa cataaagcaa aggctgttat
      781 tcttgcaaat ggagttgaaa gacgtaaatt aggttgtgca ggggaacaag aatttacagg
      841 tagaggagta tcttactgtg caacatgtga tggagccttt tttaaagata aagaagttgc
      901 tatagtaggt ggaggaaata ctgcactaga agatgcttta tttttagcta ataattgtac
      961 aaaagtgtat ttaattcaca gaagagatag ttttagaggt gaagaagtgt tggagaaatc
     1021 tgtgaaagca agagagaata ttgagatact ttacagtcat ggtgtagaaa aaatagaagg
     1081 agaaaagact gtatcgaaaa tagaagtaaa aaacttaaag actgaagaaa aaagaactat
     1141 agatgttagt ggtattttta ttgctatagg tcttaaacct aataataaaa tgtttgaaaa
     1201 tgttcttgat ttggatgaag gtggatatat aatttcagat gagtcttgta taacatcagt
     1261 agaaggtgta tatgtagcag gagatagtag aactaagttt ttacgtcaaa taataacagc
     1321 agcatcagat ggagctattg cagccgttca agcagctaat tatataaatg ttgaataata
     1381 taaatttcaa ataaaaatag ccatataaac tgaaataatt tttcagtact atatggctat
     1441 tttgttaatt agaggtaaat gtacgtttta tttaccttgt ctagatttgt tatatcttaa
     1501 tctatcatgt tcatttaaga atctttttct aagtcttata gaatcaggtg taatttcaac
     1561 taattcatca tcttctataa actctagtgc ttcttcaaga gtaaatattc taggaggaga
     1621 taattttata gcatcatctg aaccagaagc acgtacgtta ctcattttct tgtttttaca
     1681 agggttgact accatatcat cttttctgga attcatacca attatcatac cttcgtaaac
     1741 ttctacacca gggtctacaa acattacagc tctatcactt aaggcattaa gagaataccc
     1801 catagtaaca ccaggtcctt gtgctattaa aacaccattt cctcttgaag gtatttctcc
     1861 tttaaattct tcaaattttt caaatgaacg aactaaagta ccttctccac gagtagcgtt
     1921 tataaattca cttcgatatc ctaaaagacc acgagtaggt gctaagaact ctatttttac
     1981 atagtctcct tctattgaca tagactccat catacctttt ctcatgttta attcatttat
     2041 aatagtacca gagtaaactt caggacagtt tacaacaact ctttctattg gttccattaa
     2101 ttttccatct tctttatgca ttaaaacttc aggtttagaa acaccaactt cataaccttc
     2161 acgtctcata ttttcaagta gtatagataa gtgaagctct ccacgtccag aaactttgta
     2221 tccatcagta gtatcaagag gttcaacttt aagaccaaca tttacttcaa gttccttttc
     2281 aagtctatct ttcaaatgtc tagttgtaac gaattttcca ctttttccaa cgaatggaga
     2341 gtcgtttact aagaagttca tagaaagagt aggctcttct atttttatca tttccatagg
     2401 tagtggacta tctaaatcgc atatagtttc acctatagat atatcaggaa taccagctat
     2461 aacaactatt tctccactag tagcttcatc aacttcaact tgttttaaac cttcatacac
     2521 agaaagtttt gatacttttc ctttagatac aacagaatct tctctacata tagcaacttg
     2581 tgtattgttt ttaagagtac ctttgtaaat tctacctata ccaagtctac ctacataatc
     2641 atcatatgca agagctgata tttggaactg tagaggttca ttatcgtaat taggataagc
     2701 ttcaacgtga tttacaatag ttttaaatag aggagaaagg tcttcactat catcatccat
     2761 ttcaagttta gcaatacctt gtttagcaat accatatatt ataggaaatt cgcattgctc
     2821 atctgttgca tttaagtcta caaataaatc gaaaacttca ttaactactt cttccgctct
     2881 ctggtctttt ttatcaatct tgtttataaa taatattggt tttaaaccga actctaaaga
     2941 tttttgtaaa acgaatctag tttgaggcat tgggccttca ctagcatcaa ctaatagaat
     3001 aactgtgtca acagttttca taacacgttc aacttcagaa gaaaagtcac tgtgtcctgg
     3061 agtatcaact atgtttattt tgtaatcttc atagtttatt gcacagtttt ttgaatatat
     3121 agttatgcct ctttcttttt caaggtcgtt actgtccata acgcagtctt taactacttc
     3181 gttctttcta aaaacaccgc tttgagaaag gaaagcatca accaatgttg attttccagc
     3241 gtcaacgtgg gctataactg cgatatttat aattttatgt ttttgtgaca tttttgttgc
     3301 tcccttcgat taaaataact tattaattat agcacaatat attattaggt acaaggagga
     3361 atatattaaa ttgtattaat atagtttaaa ttgaataaaa ctgttagttt tgcatctgaa
     3421 aattattttg tttaaaaaaa ttttttagac aaataataac cttaatagat aaaaagatta
     3481 ataaaagagt aaaggatgat atatgttgga agtaaccaaa ataataatta aatattttgc
     3541 aagtgaaagt gatacttttg taaaagaaga agtttgtaat tttgaagaac ttcttaagtg
     3601 gtctcataaa tttattgaag gtaaaaagat agaagatgtt ttgtatataa agtctaaaga
     3661 aaactataaa gtaaatgtga ttaagtcttt agaaattaag gaattggaaa tagtgagaaa
     3721 acaacagata ccaccgtaca tgtagtatta ataatatata aaattaatat gtaatactcg
     3781 caataggata taaatggtat atatggtaat aatttatatt aaaaaaactt ttataaagtt
     3841 tatatttggg tataaaagta ttaattagac attaattagg aggaacttaa atatgataag
     3901 agtatgtcca aactgttcaa atgtggatgt aaataagcta aaaactttgg ttggagaaga
     3961 aaatgtaaag actggttgta taggtcagtg tagagcattt aaaaaagaag ctgttggaat
     4021 aatagacaat gagcttgaaa taaaggaaac agaagcagag ttttttgaag catgtaaaga
     4081 ataaatttta aataaaatat aataaataga gcatctaaat tgtataagca ttaaacaatt
     4141 tagatgctct atttttatat atacatttaa ttatgagtat acttttctat taaatacaaa
     4201 taaatataac taatacattt atttattaaa aaaatattga tttaatatac ctataggggg
     4261 tataataaaa atatagattt ctaaataagt aatttatcaa tattacatat caaaataaaa
     4321 cgttacaaat tagctgaaaa tatattgaaa gaaaggaaga ttttattatg agttcaaata
     4381 aagtggtaga aagttataaa attacaggta tgacatgtgc agcttgtgca aaggcagtag
     4441 agagagtaac taagaagatg gatggagtat atgaccaaag tgtaaatata gctactgaaa
     4501 aacttaaaat agaatatgat aattctaagg ttaattttga tgatataaag caggttgtag
     4561 aaaaagcagg atatggaatt ataaaggaag aaagtaataa aaaaattgat atgaaaattg
     4621 atggaatgac atgtgcagct tgtgcaaaag ctgtagagag agtggtaaaa aaattggatg
     4681 gagtagaaag tattagtgtg aatattgcaa cagataaagc taatatagac tatgacccat
     4741 caaaagtaaa attatctcaa ataaaagcag ctattgaaaa agctggatat aaaccaatag
     4801 aagaggtaaa aaataaggtt gatgtggatg aagataaatt gagaaaagaa agagaaatga
     4861 agtctttatt tgttaaattt atagttgcaa tagtatttgc agtacctctg ttttatatag
     4921 caatgggacc tatgataata aagcctatag ggccatggcc tttgccagaa attataaatc
     4981 ctatgacaaa tacttttaat tatgcattaa ttcagttaat tttagtaata ccagtaatga
     5041 tagctggtta taaattttat ataaatgggt ttaaatcact tttttcttta agccctaata
     5101 tggattcttt agttgcaata ggaacattag ccgcattttt atatagtcta tatacgacac
     5161 tacaaatagc caatggacaa attcaaggta tgcaccatca tcagttgtat tatgaaagtg
     5221 caggaataat aatagcactt atcttacttg gtaaatattt agaatcaaaa tcaaaaggaa
     5281 aaacatcaga agcaattaaa aagcttatgg ggctacaacc taaaactgca atagtgttag
     5341 ttgatggtaa agaagttgaa actcctatag aagaagtaga gataggagat atactattag
     5401 taaaaccagg aactaaaata cctgtggatg gagttgtaat agaaggatat acatcagttg
     5461 atgaatcaat gcttacaggt gaaagtatac cagtagaaaa gaatgttgga agtaaggtga
     5521 caggagctag tattaataaa aatggtgtta ttaagtttaa ggctgaaaaa attggtggag
     5581 atactgctct tgcccaaata ataaagttag ttgaagatgc acaaggtaca aaagcaccta
     5641 ttgctaaact tgccgatact gtatctggat attttgtacc aatagtaatt gcaatagctg
     5701 tagttgcatc attattgtgg tttttaatag gaggaaaaga tatagtattt gtacttacta
     5761 tatttatatc agtacttgta attgcttgtc cttgtgcatt aggattagca acaccaactg
     5821 ctataatggt tgggactgga aagggcgcag aaaatggaat cttgataaaa ggtggagagg
     5881 cattagaatc tgcacataaa gtaaatacag tgatatttga taaaacaggt actataacag
     5941 aaggaaagcc aaaagtaaca gatatagtat taaataataa tgtaaaagaa gaatatctta
     6001 tcaagattgc ttcaagtgca gaaaaaggtt cagaacatcc tcttggagaa gcaatagtta
     6061 agtatggaga agagaagaat ataaaatttg aaaaagttga taattttaaa gccataccag
     6121 gtgctggtat acaagttact attaatgatg aaagtatatt acttggaaat agaaagctta
     6181 tgaatgacaa taatataaag cttggggatt tagaagaaaa atcaaatata ttggcaagcc
     6241 aaggtaaaac acctatgtat atagctgtag atggaaattt atcaggtata atagcagttg
     6301 cagatgtagt caaagaaagt agtaaaaaag caatagaaat acttcatgat atgggaataa
     6361 aagttgcaat ggtaactgga gataatgcga aaactgcaaa tgctatagca aatcaagtcg
     6421 gtatagatat ggttttggca gaggttttac cagaagataa gtcaaaagaa gttgaaaaac
     6481 tacaaaatca aggaaagttt gttgcaatgg taggggatgg aataaatgat gccccagctc
     6541 ttgcaaaagc agatataggg atagcaatag gaagtggaac ggatgtagcc attgaatctg
     6601 cggatatagt acttatgaag agtgatttaa ttgatgttcc aacagcaatt aaacttagtc
     6661 atgaaactat aaaaaatata aaacaaaacc tattttgggc atttggatat aatacaattg
     6721 gtatacctgt agcagcagga atattatatg tatttggagg acctttatta aacccaatga
     6781 ttgcagcagc agcaatgagc ttaagttcag tttcagtcgt atcaaatgca cttagactta
     6841 aaaacttcaa ggcatataag agagattaga ttaataaatt aaataaaatg tatccaaaag
     6901 agctatcttt aaattaaaag gattaattta caaattaaga tagctctttt ttcatgtaaa
     6961 attcacaaca ataagataaa atataagtaa tatacgaaat tttaaataaa atagaaagga
     7021 ttgatagaat gaattcgtca atacttgtaa ttgaagatga ttcaaatata caagagttaa
     7081 tatcagaatt tttaagtgca gaaggttatc aagttgatac agcaaatgat gggttggaag
     7141 gtatacaaaa gtttaagcaa ggaagttatg atttagtaat attagatata atgatgccaa
     7201 acttagatgg ttatggagtt tgtaaaatga taagaaagtc atcaagcgtt ccaattatat
     7261 ttttaactgc tttaaatgat gaaggagacc aacttaaagg gtttgactta gaatgtgatg
     7321 attatataac aaaaccattt tcatttaatc ttcttataaa aagagtagaa gcaattttaa
     7381 ggcgaagtaa caagactata aatgacaaat ttatagtttt tgaaaaatta aaattagatt
     7441 taaacacata tattgcagag atagatggag aacctataga acttacacta aaagagttta
     7501 atatattaaa agctttgata gaaaagtatc cacaagttat aactagggaa ggtcttttgg
     7561 atagtatatg gggttatgac tattatggag atactaggat tgttgatgca catataaaaa
     7621 atataagaaa aaaaatatca ttaccatata ttaaaactgt aaaaggaata ggatatacac
     7681 ttgagaagga tatttgataa gtgggaaaag ttaagtataa agtataagtt attttcaata
     7741 acgacatcat tattaatagc attagcttta ataatatatc taattttata ttttttattg
     7801 ccatcatatt atcatgagta taaaattgag tctcttcaag aaagtttgaa atctttagta
     7861 gatagttcaa ttcatttcga tacatatact ttagaagaaa gactttatta tatggctaaa
     7921 gaccaaaatt tggctatttt attaaaagat aaccaaggta aaattgtata tggtaagaat
     7981 gaagtagtta ttttaagata tagtaagtac atgattaata gtcttgagga tgagtataga
     8041 acttctatac ctatatatac taaagatgca aaagatggtc catatacttt agaactcgtt
     8101 atgccattac aaccaattga cgaagcaaac gaagttataa gaaaactaat gccatacatc
     8161 atatcaatag caatattgat agcgattatt ggagcatata tatattcaat tgtaataaca
     8221 aagcctctta taaacataat agagagtgag agagaacagg aatatagaag gaaggatttt
     8281 gttgctacaa tatcacatga actaaaaact ccaataacca taataagtgg tcaaattgaa
     8341 ggtatgattt atagtgtagg taagtataag gatagggata cttatctgaa aaaatcgtat
     8401 gagtgtacac aagaattaaa agatttagta aatgaaatga tagaggtttc aaaatcagaa
     8461 atacttgaaa aagatttgaa attggtatca ataaatataa gtgaattatt aaatagactt
     8521 gtaaagagac aagtattttt aatagaagaa aaacatatga aaactatttt aaaaatagaa
     8581 gaaaatttgg aaattaaagc agaccaagag agaataacta aggcaatcaa taatataata
     8641 aataatgcca taaaatattc tcctgaagaa tcagagctta taattagact ctatgataaa
     8701 aataaacgaa taagtaaaaa gacttctaat caaagagtgg ttttagaaat tgaaaatact
     8761 ggtgtaacta tcgagaaacg ttatttagaa gaaatattta atccatttta tagaatagaa
     8821 aaatctcgtt cgagaaaaac tggaggaagt ggacttggac tttatatagt cagccaaatt
     8881 tttaaaagtc atgggtttga ttatagcata aaaaacaaag aaaactctgt agtattcaca
     8941 gtagaattta aaaattaatt acttattata aagaatatat aactttcaat aatagttcat
     9001 tttaaaatca caaaaaattc ataatgaaac tgtattatat aaatataaat aagcttaaaa
     9061 ccataaaata caccaactat aatgatgaga tttccttaca tcctccatat aagtcatcat
     9121 tatagtaacc caacaattaa gttactatga atttaaaaaa taacaccgag catataatct
     9181 atgcttagtg ttatttttat tttgaaataa aaaatattta atttattgaa atgtatagat
     9241 ttagatagtt taaactatat ttaagactta aaaattataa ttgatattac aaataaatat
     9301 atgtactttg ggaaaaataa atataggaag tattatattt acagaggagg tagttttgat
     9361 ggatagatta aaaagagata tgaaaaatat gaaagaagat ttaaaagaag gtgttaaaaa
     9421 gacagcttat gttatgaaaa atacagctga agatttgaaa gatgatgcac aaggtgctat
     9481 ggtaaactta gaaatgaaaa aagatgagat gatggaaaga tatgaacaaa agaaattttc
     9541 taaagaatta gagaagcaaa tgaagaatga aatgaaataa gcttttattt atgaataaca
     9601 aattattgta ttcatataaa aagtagccag taatattaaa tagtttattt aaggaaatag
     9661 actttctaaa aataactgta ttagatttag aaagtctatt tcaaattagt tttataaata
     9721 gacataagga taaagtagat gttatagaac tagattttaa aaaatagata ctaaggataa
     9781 aataaatatt atagaaatat gtttttaaga atatttatca aataaaaatt tatatttata
     9841 agaaatccta taaaacatat aattaaactt ataaaacatt tacattaaat tctgataaaa
     9901 tatctactat atcaggagta ggcgtttttt ctgtaattat agaactaata tcttctaaat
     9961 gagcaaactt gaaatttcca tcaaatttaa actttttatc ttccataact ataaatactt
    10021 ttttacttga atttattata gccttcttcg taagaccatc ttcaatttca aaagttgtaa
    10081 gtgaagagtt gaatacatct actccacaac ttcccataaa agtcttatca aacttatatt
    10141 tcgatataaa ctctatagtt ggagtaccga caaaaccgtc taaactgaga tttaataaac
    10201 ctccagtgga aattatattt aaattatttg gttttgaagt aactacattt agtatatcca
    10261 gcatatttgt aacaagtgtt acttttttat tactttcagc taacaacttc gcaagcaaga
    10321 tgttaattgt agagatatct aaaaatatag tttctctatc ttcaattaaa ttaaatgctt
    10381 tttctgctat tattttcttt gttggaatat taatttcttt tctgtctttt gtatcctgat
    10441 tctctagtgt ttctctagct agtacagctc ctccataaat tcttcttatt gaagaaatct
    10501 tttctatatt ttttaaatct tttcttatac aatcttctgt aacattaaat ttagaactga
    10561 gctctttgac agtaactcta ccttcttttt ttaggatatt taatatagct tggattcttt
    10621 cttctgcaaa cattttctac ctcttttcgc aatatagtat tatagtaaat attataagat
    10681 aaaatacaat atatcaacta ttttaacatg aaatacaaaa ttaatttaat ataaaaagta
    10741 tgttttttct aactatatat ttagaattta gtaaataaaa aaattataaa actaagaagg
    10801 aaaagtaaaa caataataaa aaataaaaaa caataagcaa aatgttgaaa ataataccaa
    10861 atcaatatat aataagaata aagaaagatt aaagggggat attttaatgc aactaatctt
    10921 agatacaggt aatgtggagg agattaagga gttatgtact tgtttaccaa tagatggtgt
    10981 aactacaaat ccaagtattg tttcaaaaga aaaaaagaat tttaagcaac ttataaatga
    11041 aattggtgag attataggtg aggatatgcc tatacatgct caagtgttaa gtacaaagta
    11101 tgaagaaata ttagaagaag cattatatat aagtagtttg agaaaaaata tatatgtaaa
    11161 aatacctgta acacaagatg gtttaagagc tataaaagac cttcacagaa aaggtgtaaa
    11221 aataactgct actgcaatat tcactgctca tcaaggtttt ttagctgcaa aggctggagc
    11281 aaattatatt gcaccttatg taaataggct tgataatata tctggtgatg gagtagctat
    11341 ggtttcagaa cttataaaaa taatagatac ttataaaatg gatacaaaag tacttgcagc
    11401 cagttttaaa aatgcacaac aagttataga attaatgcaa catggggtgc atagtgttac
    11461 agtaccatat gatatttgta aatctatgat gaatcatcca ttaactgatt ggagtgtagg
    11521 taagtttata gaggattggg agaatacttt tggaaaagga agtaaaacaa ataatattta
    11581 gtattatggt aaaagagtag ttttgtccaa tttcacaaga acttatataa aaagatgaaa
    11641 atatgaattt tctttttaat aatttcgtta ttatcttaag ttaattcata ttttcatctt
    11701 ttttagattt ctagtcctat aaatttccac caagggaatg ttatacatat tattataaag
    11761 taggttaaag gaatcaaagt taaaccgtat ttgaaaataa ccttgctatt atacagattt
    11821 tcaccatgac caaccattat tgtagcatga tgaaatggta atatgtactg tatgcttact
    11881 ataatgtaga caaatagaca taaagtaaca ctattttcct ttagtatatg taaacttcca
    11941 agtaacggta ttactacaga tgatgtagtg acagcacttc caagacatat attcaagatt
    12001 attgtgagag ttatcaaaaa caatattgaa ataatttctg aagagtttgg tataaacttt
    12061 atcaaataat ttcccattat atctacaact ccagagtact ttaacactcc tccaattgaa
    12121 aatgctgcta taaaaaaaat aaggaccttc caatttattt cttttaaagt actaaatcca
    12181 actatttttc ttagtaataa aagaagtaca caaattgaca ttataattaa tgtgtttatg
    12241 ttatgtatga actgagttaa aaacataaaa aacattattc ctaggcataa aaatacgtgt
    12301 ttttgctctt tgtttagcaa attaaattct ttttttaaat tagaatatga aaaatgaagt
    12361 ttattaccct caagattttc attagaaata aattttattg aatgcaattc ttttttaaag
    12421 acaaagataa ataaaaaata agttataaaa caagtaatta tagttggaac agacatataa
    12481 aaagcccatt gaccccaatt tatattacaa tttccaagtt ctagtacaac ataatttaga
    12541 agggtgtctc catttacaaa aaacattgat gtaaaggtag atgctgtaaa tatactaaat
    12601 aaaagtatag attttgaatc ttcagttatc tgttgttctt ttaaaaactc cttgtaaaaa
    12661 gcagatacaa gaataaccct tggaaatggt tgtgggataa aaaatattaa aagtatacct
    12721 aaaatatacg ataaaagaat cattttttta ggggtattta cagtatttaa aattaacttc
    12781 tcagaaataa tttttgcgac acctgttttt gtaactgcat tagtaattat gtatgcaaga
    12841 attattatgt aaaaattttc tgtaaataaa aactgtaaaa taacctttat tggtgcaatg
    12901 ttaaatataa acgctagaat tacaaaaaac aatgcaacaa aagttttttc aactgagtct
    12961 acagcccata tcaagatagt taaaaaagat aagcatatag aaaattttat gttgaaactg
    13021 taattaagag agaagtagag aattatggta gctataacag tcatataaaa ttgttttggc
    13081 ttaagaataa tacccatttt tatattcacc tccataattt attatatcat aatggaggtg
    13141 aatacaatga atgtgaatac attttataaa aagattattc attgattcta tgatttacaa
    13201 tagctttagt tttccaatgt cctttcttat agtagataac tgtaacaata agacctaaag
    13261 tccaaccaaa aggaataccc atccaaattc cgtctgttcc aaaaaattta gaaagcatat
    13321 aagaagctgg aagtcttcca agccataaag atactattga gcttataagt gcaaacatgg
    13381 aatcaccagc acctttcatt gcacttgaaa gtacaaaaga agttccaata aataagaaga
    13441 atggtcctat tataaataag taagaagagc caattttaat gacatcttta tcagtattga
    13501 atagagcaat tagattttcc ctaaatagca aaattaaagc aataactgta actgctaaaa
    13561 ctaaggtcat ttttatagat tctcgaatgc cttttttaac tctttcattt tctccagcac
    13621 ctatgttttg agcaacaaaa gtagaaacag cagaaccaag attcataata ggtaagctta
    13681 taaaattttc tatcctaaga ccagcaccaa aagctgccat agcagatgta ccataactat
    13741 taactaaaaa ttgaagagcc atatttccaa ttgaaaacaa catttgttga actccacttg
    13801 gaagtcctaa tctaagtcca tctttaaata ttttgttatc atatacaatt cctttgattt
    13861 taaatttaag cacttcatgt tttttattta aataaattat acttattata aatgatactg
    13921 cctgagccat tatagtggca agtgcaacgc cctcaacacc cattcttagc actacaataa
    13981 aagttaagtc taaaactata tttagaattg tggctattat cagaaaataa agtggagtta
    14041 ctgaatctcc aagtcctcta agtattgcac ttactgaatt atatccagca gaaaataata
    14101 ttccactaaa tattatagta agatacaatt ttgattgagc aaaaacggat tctggtgtat
    14161 tcataagctt aagcattggg ccaccaaata ctattccaag aatacttatt aatatagaac
    14221 caataaataa aagtatatat gtagtatcaa tagtagcttt tacctttttt aaatctcctg
    14281 agccataaaa ttgtgacact aaaatagaaa atccaaggct aacacccata agcgctgcca
    14341 ccaataaaaa cattataggg ttagctccag agactgccgc cattgcttct tttccgataa
    14401 atctaccaac tattatactg tcagctgtat tgtatagttg ttgaaataaa ctaccaataa
    14461 gcataggcat ggcaaaaaag aatatggact ttccctcatg acctgtagtt aaatctttca
    14521 ccttattcct ccaaataaaa aaattattaa tttattatag tataatctta acataaactt
    14581 tatatccaaa ctataaataa attgtatcaa aatatcatat atttttttaa aatgtaaaga
    14641 atataattat aatttgaatt taataaatca atatttaata taatcgaata ttaatacaaa
    14701 atcaatacaa tatatacgta tatattgaca aaattaatta tataaattaa aataatattc
    14761 gtaaagaaaa attcatgttt tgtactgtat aacatataat tttgacaata tgggtcataa
    14821 gtttctaccg gaataccgta aatattctga ctatgtatac tattatttag ttaattaaat
    14881 atttaattaa ctgaattatg aaggatacgg ctcagcttat caactactgt gtcgtttttt
    14941 tgtaaaattt aataggaggt gttgttatgc aaacaacaaa cagtagtact atgcagaaac
    15001 tttttccaat tttgactaat aaaaatgtcg acatgaagaa ggaaataatt gcaggagtaa
    15061 ctactttttt aactatggct tatataatag ctgtaaatcc aaatatttta tctgagacag
    15121 gcatgcctgc aggtgcactt gttacaggta cttgtttagc agcagcattt ggatgtattt
    15181 taatgggtgt agttgctaac cttccttttg ctttagcatc aggtatgggt cttaatgcat
    15241 tttttgcata tacagtagtt ttacaaatgg gtgttccttg ggaagtagct cttacagcag
    15301 tatttgtaga aggtattatt tttatagtat tatcagtaag tggagttcgt gaggctgttg
    15361 taaatgcgat accaaaaaat atgaaattag ctgttacagg tggtatagga atatttattg
    15421 cacttatagg tctagttaac agtggaattg ttattggaga ccaagccact cttatcaaaa
    15481 tgggtagatt tacaccagca gtaataataa cttgtgtagg attaataatt attgctgtat
    15541 tagataaaaa aagagttaaa ggttctatac tttttggaat agtagtgagt tcattacttg
    15601 cttgggcatt tgcttttata aatccagagt atgcacaaaa attaggtata tatttacctg
    15661 gtggattatt taaattcgaa agtttagcac caatagcagg taaaatagat ttaggatatg
    15721 tactacatcc aacaaatata ggtggttttt tagtagtagt ttgtacattt ttatttgttg
    15781 atttttttga tacagtaggt acattagttg gtgtttgttc taaagcaaac atgttagatg
    15841 aaaaagggaa tgttcctaat gtaggtagag ccttacttac agatgcggtt gcaactacag
    15901 ttggtgcagg acttggagta tctacagtta caacttatgt tgagagttca acaggagtta
    15961 tcgcaggtgg aagaactgga tggacagcaa taacagttgg aattttattc ttagctgcaa
    16021 tgtttttctc tcctgtattt atagcaattc catcatgtgc tacagcacca gctttaatat
    16081 atgttggata tttaatgctt ggtacagtta aggatataga gtttgataat ataactgaag
    16141 gtgttccagc ttttgttact attgcttgta tggcattaac atatagtata ggtgatggtt
    16201 taactttagg tatattaact tatgttttcg taaatatatt ttataatata tttggagcta
    16261 aaaaggcaga agacaaaaaa catgtttctg tagtaatgat tgttctggca atattattta
    16321 taataaaact ttggctacta taataggtat tatttaaaat tttaatttaa tataaaataa
    16381 agggctgtaa tttattatca attgtgatga taaactacag ctcttttgta tttgttgtat
    16441 ttttgtattt attgtattat ttaataatgt ctattagttc tccattttgt aaagttttag
    16501 gtgtaattac tatattgaac tctttttgca aatcttttat aatatctaat tctttttttg
    16561 ttattattga gattgtgtta ccacttcgat ttcctctagc agttcgacca catctatgca
    16621 ggtattcatt tttacttttt ggaaaatcca agttaaaaac atgacttaca tccacaatat
    16681 ctagtccacg agcagataaa tcagttgtaa ttaaaatctt tgctttacca agtttaaatt
    16741 tatttattgc attctttcta tcttcttttt ccatatttcc aaaaattcct attgctttgt
    16801 aattatgata atttagtttt gatactagga cttctatatt tttttcatta tttacaaata
    16861 caatagcttt ttttggattt gtagctgcta atgcctttct aagaaaagta aatttatccc
    16921 ttatctcacc taataaatat gagtgattga tgttaggatt tatttgtgat ttttcctttg
    16981 tttttattat ttcaaactcc ttcataagtt tatcacaaat ttttatagtg ctatcagtaa
    17041 gacttgcaga gcatcctata atttgtctat ctcttaacgt tgttcttatt atgtcttcta
    17101 tacaagttat attttttcca ttcaatagat tgtccacttc atctaagata atagttttta
    17161 tattatgtga ttttagtttc ttttgtttta tcaagtctaa aactcttcca caagagccaa
    17221 ttactatgtg tggttttact gcttttatat tttttatttg tttttgtata ttgacctccc
    17281 caattaaagc taaagaagta acggagagtt ctgcattttt agccaataat tcaacctggt
    17341 ttgtaatctg cattactaat tcatgcgtag gtgcaagtat aagagcttgt gtttctcttt
    17401 ttgatgtatc aattttttca aatataggta aaaggtatgc tagtgttttt cctgttccag
    17461 tctgtgaatt aatcaataaa tccttatttt gaattatatt ccctataaca agtgactgaa
    17521 cttctgttgg agaagttatg tcttgttttt tgagtccatc tattagagtg gaacttattt
    17581 ttaattgttc aaatgtattc atattttact ccttatattt taataattat agtcaactat
    17641 tttttattat acattgttta ttcaaatcga actatatatt cttttataat tat
//
LOCUS       DAMJWC010000077        17548 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMJWC010000077 DAMJWC010000000
VERSION     DAMJWC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17548
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.078"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     misc_binding    198..429
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            537..2018
                     /locus_tag="PC503_003039"
     CDS             537..2018
                     /locus_tag="PC503_003039"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF2529004.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            2028..2921
                     /locus_tag="PC503_003040"
     CDS             2028..2921
                     /locus_tag="PC503_003040"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF2529005.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            3045..4106
                     /locus_tag="PC503_003041"
     CDS             3045..4106
                     /locus_tag="PC503_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF2529006.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(4261..4773)
                     /locus_tag="PC503_003042"
     CDS             complement(4261..4773)
                     /locus_tag="PC503_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF2529007.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            5293..6228
                     /locus_tag="PC503_003043"
     CDS             5293..6228
                     /locus_tag="PC503_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF2529008.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(6320..8191)
                     /locus_tag="PC503_003044"
     CDS             complement(6320..8191)
                     /locus_tag="PC503_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF2529009.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            8381..9307
                     /locus_tag="PC503_003045"
     CDS             8381..9307
                     /locus_tag="PC503_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2529010.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9446..9592
                     /locus_tag="PC503_003046"
     CDS             9446..9592
                     /locus_tag="PC503_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529011.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(9697..10221)
                     /locus_tag="PC503_003047"
     CDS             complement(9697..10221)
                     /locus_tag="PC503_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2529012.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(10274..10498)
                     /locus_tag="PC503_003048"
     CDS             complement(10274..10498)
                     /locus_tag="PC503_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529013.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            10695..11819
                     /locus_tag="PC503_003049"
     CDS             10695..11819
                     /locus_tag="PC503_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HDF2529014.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISTFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSDSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(12293..13117)
                     /locus_tag="PC503_003050"
     CDS             complement(12293..13117)
                     /locus_tag="PC503_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529015.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(13465..14520)
                     /gene="ispG"
                     /locus_tag="PC503_003051"
                     /gene_synonym="gcpE"
     CDS             complement(13465..14520)
                     /gene="ispG"
                     /locus_tag="PC503_003051"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF2529016.1"
                     /translation="MSYERRKTREVSVGAVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(14703..15707)
                     /gene="rseP"
                     /locus_tag="PC503_003052"
     CDS             complement(14703..15707)
                     /gene="rseP"
                     /locus_tag="PC503_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF2529017.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(15720..16874)
                     /locus_tag="PC503_003053"
     CDS             complement(15720..16874)
                     /locus_tag="PC503_003053"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF2529018.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(17038..17241)
                     /locus_tag="PC503_003054"
     CDS             complement(17038..17241)
                     /locus_tag="PC503_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529019.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         6050 a         2720 c         2079 g         6699 t
ORIGIN      
        1 tactttcatt aaaaacagct tcatcactat gaaaatctag gtttttaaac ttttaaaaaa
       61 gttaaaaaaa tatttttcta atactcaatt tgattacaat ttttttacaa tttaaaaaat
      121 attttttcca aatttttata ttaatacttg actttgtctg ttttataaac tagaataatt
      181 aataatatta agaatattga aaggcattga ttaggaagag taaatctgaa tcgattacca
      241 gagaaggaaa ctactagctg aaatgtttcc ctaattagaa ggattgaaaa ctacctagga
      301 gcttctatcc gaagttatct taatgatttt agtaggaata gacgttttta ttacttgcgt
      361 taaagtatca agtggatttt ttaaaatcaa tttgggtgga accgcgggaa acagattctc
      421 gtcccttttt tagggatgag ggtctttttt tattacctaa attcagtttt taaaatattc
      481 tgtatctaat ttaattagct aattaaaaat ttaaaatata tggaggatta taaaaaatgt
      541 attattcaag tacgagaggc accgaagaaa aagtaactgc atcacaagca ataataaaag
      601 gaatatcaaa tgatggtggt ctttatgttc caagtgaatt tcccaatgta aaaaatgaac
      661 ttataaattt agtaaattta acgtattctc agatagcatt ttttgtactt agtaaatttt
      721 tatgtgattt tactgaagat gaaattaaaa attgtataga aaatgcatat gatgaaaagt
      781 ttgattgtag tagtatagct ccattaaata aagtaaatga tacttatttc ttagaactat
      841 atcacggtcc aactttagca tttaaagata tggcacttac tataatgcct catcttctta
      901 aaacatctat aaagaaagat aatttagaga aagatgttgt gattcttact gctacatctg
      961 gagatacagg taaagctgca cttgagggat ttaaagatat agataaaata aagataattg
     1021 tattcttccc agaagatggt gtaagcccag tacaaaaact tcaaatgaaa actcaaactg
     1081 gaaaaaatac atatgtagtt ggtataaaag gaaattttga tgatgcacaa tcaggtgtaa
     1141 agaagatttt ttctgataaa gaatttaatc aaaaactatt ggataataat tatatattat
     1201 cttctgcaaa ttcaattaat ataggaagac ttcttccaca agttgcatac tatttttatt
     1261 catatatgaa attagttagc aatagtgata taaatttaaa tgataaaata aattttgttg
     1321 tcccaactgg taattttggt aatattctag ctggatatta tgctaaacaa atgggtcttc
     1381 caataaacaa attaatatgt gcatcaaatg ataataatgt tctttatgat ttctttaaaa
     1441 ctggtgtata tgataaaaat agaacattga aattaactac ttctccttct atggatatat
     1501 taatttcaag taatttagaa cgattactgt ttgaaatatc aaatagaaat actgatattg
     1561 taaataagct tttatcagac cttagtgata aaggagtcta caaaataagt gatgatatgg
     1621 aaaaaaattt agcctcattc tatggagaat attcaaatga agaagaagtt aaaagcacga
     1681 taaacaatgt gtttaaaaat tataattatt tgatagatac tcatactgct gttgcataca
     1741 attgttatga aaaatataaa aaagaaactt ctgataacac aaaaactgtt attgtaagta
     1801 ctgcaagtcc attcaagttt tctgaagatg ttctaaagtc tatagattgt gattttaaag
     1861 accttgatga ctttgctata attgatagat tatcaagtat ttctaaaata gatattccaa
     1921 aacctattaa aaatcttaaa aatgcagaaa tactacataa agatatttat gaaaaagatg
     1981 aattaaaact agctataaaa aaattcttaa aggtataggt gattattatg ttagagatta
     2041 tagttcctgc aacaagtgct aatataggtc caggatttga ttgtcttgga attgcgttaa
     2101 atatatacaa taaattttat gttgaagaaa ttgaaagtgg tcttgaaata gaaggttgtg
     2161 aagatgctta caaaaacgaa aacaacttag tttatacatc tatgaagtac ttttttgata
     2221 gagttaaacc agaaaaaata cctgctggta tcaaaataaa aatccaaagt gaagtaccta
     2281 tatgtagagg tcttggcagt agtgcctctt gtatagtagc tggagttata gctgcaaatg
     2341 ctctatcagg tgctaattta gataaaaatc aattactaaa tatagcttca gaaatagaag
     2401 gtcacccaga taatgttgct cctgctattt taggaaatat gattgtatct gttactgata
     2461 atgagaatat acattatgat attataaaaa ttcctgaaga acttaaattt tgtgcaatga
     2521 tacctaattt taagttatca acagaaaaag ctagaggtgt tttaccaaag gaaataccat
     2581 attctgatgg ggtattcaat gttagtagag ttgctttact aatatctgcc ttactaaaca
     2641 aaaactttga cctacttaaa gtagcttgtc aagacaaatt gcatcaagat tatagaggaa
     2701 ctctaattga gaactacaat gatattgttg aaaaatctga acaattaaat agtattggag
     2761 tatttttaag tggagctgga cctactataa tgtctttaat aaaagaaaat gatgatagtt
     2821 ttgtggataa tatgaaaaat tacctacaaa aactaaaatc tgattgggaa ataaaagagt
     2881 tatgttgcga ttctaatgga gctgttttaa atataatata attatcgtct tctatacaaa
     2941 atataactac tcttttatta taatttgtag tataataatt aggactaggt aataatatta
     3001 agtattataa tctagttctt taaacatgtt tacattgagg agggattatc ataaaagagt
     3061 taataattag agatttagtt gcaaaagttc ctataattca aggtggaatg ggcgttggta
     3121 tatctaggtc atcactagct ggtgcagttg ctaagcttgg tggtgttggt gtaatttctg
     3181 gagttcaaat tggatatgat gaggaagatt ttgaaactaa tactataaat gcaaatttaa
     3241 gagctataaa aaaacatatt tctaaggcca aagaaatctc aaatggtggt attattggta
     3301 ttaattttat ggtagctatg aaagaatatg aaacatacgt aaaggaagct gttaaagctg
     3361 gtgtagacct tataatatct ggagctggat tacctaataa gctaccatca ttagtaaagg
     3421 gaagtaatgt aaaaatagca cccatagttt caactgcaaa agctgctaat gtaattttaa
     3481 aaatgtggga tagaaaagag aaaactactg ctgacttaat agttgttgaa ggtccaaaag
     3541 ctggtggtca ccttggatac tctaacgagg aacttgataa catagattct atagactatg
     3601 ataaggaatt tgttgaaatt ttaaaggttg caaatactta tggagaaaaa tttggtagaa
     3661 acataccagt agttgctgct ggtggtataa cttctagtag tgatgttaaa aaatatatag
     3721 atatgggtgc aagtggtgta caagttggta caagatttgt tgctacttac gaatgtgatg
     3781 cccatgagaa ctttaaaatg gcatacataa atgctagtga agaagatgtt catatagtta
     3841 aaagtcctgt aggtcttcct ggacgcgcca taagaaacaa atttatagaa gaagttaaaa
     3901 taaatcgtcc agaaataaag aagtgctata attgtttgat tccttgtaat ccaaaagaaa
     3961 ctccttactg tatttctcaa gctctaatca atgcagttaa aggagatgtt gaaaattcac
     4021 ttttattttg tggaaatgat gcctataaaa ttgataaatt aagtactgtt gaagatgtta
     4081 tcaatgaatt gatttctgaa ttataattta aagaaaacta aattaaaatt ttatcaagct
     4141 aaggagttta aatacgttat ttattaatct ttataaacat atttatgtcc ttagcttttt
     4201 tgtgtcaatt tccttttatg gaaattttaa tttaattaga gatagtatta acctttataa
     4261 ctaatcttct tttacaagta cattggttat ttcagctata tataaagtat gataatcttt
     4321 ttgtggatac catcttccat ctataccttc agcaataaaa cattgaggtt caagtttctg
     4381 actatacatt tttttgcata taatagccat tttagattct ttaaaataag gtgtatcatt
     4441 taagtgttct atattaaatc caatctgtga tatcttatcc tcttctctac cagatacctt
     4501 tccacaatat gaaagctctt tacgaaaatc ttcatcaaaa aatgtaagag aaaatttatc
     4561 tgtattatct ataaattcct tagtataacg ctgtggtctt attactacaa aagcaacatc
     4621 ttttccccac ataactccaa gccctcccca gctagcagtc attgtattca ctttaccttc
     4681 attttctgct gttataagtg tccaatcttt acctatcaat ccaaatggat tatttttaat
     4741 ctcttctgcc aaaatctctt taaaatcact catatctcta ataacctctc attctcttat
     4801 atttatattc cttttatttt cgtgataaat tataaatgaa gtctagtttt gaaaataaaa
     4861 tactttttta aatatattat tgcaaataag taaatatata tatactctct tattttttaa
     4921 tatatttaat aatttcactc agaatatata tattctttac tcaaattaaa tataacttat
     4981 atactttatg tgtaaattat ggtaaaaata ttatttaatc aaatcaaaac ttgatttata
     5041 tacctggaaa aggtattata ttaaagagtg cttaaaatac gcatttcata aatagctata
     5101 tataaaataa taaataagga gagtgatggg caatggatac tagtccgttg cggagagaat
     5161 tttttacatt ttcatcactt aataatatct aaaatcaaaa ctaatacata tattcagtta
     5221 tataaattag ttaattaata gatactatta aatgatgaga tttatataaa actgaataaa
     5281 ggatgtgttg ccatgataag atattacaaa actatagatt caaaattaga gaaacttagt
     5341 ttttttgaag atggctgttg gataaatctt gttgaaccta atcatagtga aatcaacgaa
     5401 atttctaatt tattaaatat agatgtagaa agcatagaat ctgcactaga tgaagaagaa
     5461 cgctcaagaa tagatgttga agacaatcat actcttatac ttatagatat accagtagac
     5521 gaaagtgact ctaattcttc tcattatact acaataccct taggtattat actaactgaa
     5581 gaagctattg taacagtttg tgatgcacaa actaagattt taaatgactt tatagttggt
     5641 catattaaag atttttttac gtttaaaaag actcgctttt tgcttcaaat tcttcacaaa
     5701 aatgcagctt attacttgca ttacttaaga aaaataaata aaatgacaat cataatagag
     5761 cgagaaattt acaaatcaat gaaaaacaaa gaattggttc aattattgga attagaaaaa
     5821 tctttggtat acttctctac ctcactaaaa tctaatgaac ttgttttaaa caaaatggtt
     5881 agaactgctg gtataaagaa gtatccagat gatgaagacc tattagaaga tgttatagtt
     5941 gaaaatagac aggctcttga tatggctaaa atatatggag atatattgag tagaattatg
     6001 gatgctttca gtgcaattat aagtaataat cagaataatg ttatgcaaat tttaacagta
     6061 gttacactaa ttttctcaat acctacaata atatcaggat tctttggtat gaatgtcatc
     6121 aacatgccat tttctaataa cccaaacgga ttttggataa tacttcttat tacctctata
     6181 atatgtatag tgattacatt tttcatgtca agaaataagc tattataaaa tattaataaa
     6241 aaggccatta gaattaattg atttacattt atcctaatgg cttttatata tttaaatcta
     6301 tataatctta taatactttt taactatcat gttcttcatc tataatcatt tcagtttcaa
     6361 gcccttctag cattgaatct aaactttctt ttatatttag tatataaatt ggtacatact
     6421 cttcttcatc tattacctct tcttgcaact taaatggagg aattaatact tcatcaaagt
     6481 ctatatttaa atttggaaag ccttctacta tctcttcaca attatcgtac tcttcatttg
     6541 ctaaagaaat gtacatatct aggctctttt tataataaag acctgcaagc atatactcac
     6601 acttcttact tccatattta ataccttctt tataatattt ctcagcttct gcgtcatcat
     6661 ttaattttaa ataaatttga cctaaattat atattgattc aacacaacct tgtgctctag
     6721 ccttttcata ccaaaattta gaatttacat aatctttata gaacatatca taaattaatc
     6781 ctaccatatg ttgagcatac acattatttt cattggcagg tgtatcaaac atcattttag
     6841 actcttccaa tttaccttct ctaaaataaa ttctacctag atgtatacga gcattcatat
     6901 ggtttttgct acttgccatt tcaaaatact ttctagcatt ttttgtattt cctaagctct
     6961 catatataca ccccaatcta taactagacc tcgtatctcc attttcagat gctttcttat
     7021 accaacttat tgcttcttca atattattta aatcttcata gatatttcct aatttgattt
     7081 gacaagatac attatttgga atcctcgaat aatacgaaat cgctttttct atatcttgat
     7141 tctgataata taaatcccct agattttcaa gggaactttt gcatccaaca gctatagcat
     7201 cctcataata tttaatagca ttttcataat ctttttcttc aaaatatata cctgccagat
     7261 tattttttgc ttctgttata tcatcttcag cagccatttt ataataagtt tttgccttct
     7321 ctatctcatt ttctctatta tataaattag caagtctata cttagaaagt gtatgatttt
     7381 tttctattgc tttctcataa taataaattg catctcccag ctcttctttt ctatcatata
     7441 catatgcaag cctatactca gacttcacat catctctatc agcactcttt ttataatact
     7501 tctctgcatc ttctaaatta tcatttattt ccataatcat acccaagtta aagcaacctt
     7561 tcatatgacc tgacttgtac aactgtttat ataaacttac tgttgattta ttatctttct
     7621 tttttccatt taatattgct aaattatatt ttgcatcatc atctaaaagc acagaacctt
     7681 ttttatagta ttcatatgct tcatcatctt tctccaaaaa agtatataat acccctaaat
     7741 taaaacaagc tttacctaaa ttcttgtctg ctgctgtttt taaccatttt tcacacctta
     7801 caaaatcttt cattttaaaa tggcatacac ctaaattatt ttgtgcttgt aaataaccta
     7861 aatttgctat cttttcatac caatatatag catattcata gccatctaac ttatagtaca
     7921 tattacctaa atcaaaagca gcatcttcac ttccactttt atatgccatc gaataccact
     7981 tttctgcttc tttaaattgt tttttacttt catatatatt tcctaaagta tattgagatt
     8041 ttacgtaatt atccaatgca gcactcttat acaactctat tgcgctttcc atcttaccca
     8101 tcttttcaag gagggcaccc ttagtatgta cgactttcgg gtcattagat atatttttta
     8161 ttttttttat agaaaatttt gtatttttca ttattcgcta cctacccatt ttataaaata
     8221 tattctctca aacattatta tacattataa tctacaatta atgctataat attgaatttt
     8281 taccttttgt cactatattg taacattaaa ttttaaattt tataatcatt agattttatt
     8341 atgtaattgg tatataatgt atatataggg gggacatttt atgaatttca gcaatatttt
     8401 tatccaagtt gcagttttat ttataattat tttagttgga tattttgtca gaaaattcaa
     8461 cttattagat gaccactgca catctaagct ttcaactttg acaatgacag tttttttacc
     8521 atcaatgata attagctcca tgcaaattaa ctttgatagt aaaatgatac aaaaaatact
     8581 attgttatta tttacatctt tgattatgta tatagtttca attataattg catttttatt
     8641 gaaatacatt ttaaaatgta atgataaaaa agatttggga atataccagt atatagttgt
     8701 tttttcaaat gttgctttta tgggttatcc tgtaattgaa gcagttttag gtcatgaagc
     8761 aatattctat actgcaatat tcaatttgcc ttttaactta ttttctttca ctttaggaat
     8821 ttatctttta tctaaaggca gtacaagtag aggtttttca ataaaatcac ttataagccc
     8881 tgctacaata gctattgtta ttggactttt tttatttgta acaggactta ggttacccca
     8941 atttataaac gagccacttg agatgttggg aagtataact acaccaatat ccatgattat
     9001 cattggaagc ttacttgcta attcttcagc tctcgattgt tttgtcaaca aaaaattata
     9061 tatagtcact tttataagat tattggtact tcctgtgatt gtgtatttta ttctaaaagg
     9121 atggataaat gataagatga ttttagctat accagtagta atttcttcaa tgcctgctgc
     9181 tgcaaatact gctataatgg ctaatcaata tgactccaat ataacactag cttcacaatg
     9241 tgtgtttttt acaacactat tttcagttat atctatacct tttataagta ttttactctt
     9301 atcttgattt atttttttat gtattatata ataacatatt caataaatta caaatataaa
     9361 cattttattg tagtatattg atggaatttt ttcctagata tttgtcaata atatctatat
     9421 gtattataga ataggaggct taaatatgga tatggattta ctctttaaaa tagtatttgc
     9481 tatagttgct ataggtgttt ctgtaaaaat cattaaaact gttgctagtt tagcttttaa
     9541 aatagcgttg atattgctaa taattttatt tgtatataga atgtttttgt aaacatttaa
     9601 aaataagttt tttaacacaa tagagaagta aaatagatta tctttaatgt aaatttttta
     9661 ttaaagacac tctattttac ttctctatta gcttctttaa attaaatttt tattatatct
     9721 tcccataata taaacatctt caaattttcc atctctgatt acagcatatt ttttagttcc
     9781 ctctatttca aaacctagct ttttatataa atttaatccc ttttcattat ccacaattac
     9841 ttctaatcct actctagtta acataatcca attatctgct atatctaaaa gttgttccat
     9901 aagcttctta cctactcctc ttccctgata attctctgca acacttattc ctatttctgc
     9961 gctatgtctc aatcgtggag aagaatttac atgtaaccca gcaaaaccta ttacatcttt
    10021 ttctccatta ttattagttt cagctacaaa catataatca ttttctccca aagaagctaa
    10081 catagcttca gttttatcga ctctgtcact cattaatgcc aaagtatttc tcataacact
    10141 gtatgttctt ctaatttcat taaaagcttg tgcatcttct cttcttatag gtcttattgt
    10201 tatatctata ggcttactca tattggattc cccctcaaac ataatcttta tttttaatta
    10261 aaattttaca tctttatttt atactgttca aatctatgta tgcttctacc tgaggtacat
    10321 atatcatatt atcttttata tgtgtacttc caaattcttt taattctgta ccttctttat
    10381 ccttagttat tttatatcta atggattcca taccttcaac tacttcagca tgaaaaaaca
    10441 taccttcata ttgtttaaat ctaaaattaa aattgtcttt agtaagtttt attatcatat
    10501 ttttatctac tccttatata attgatattt ttcttattat tagttgtata tatactgctt
    10561 attcatatta atatattata acttatcatt tatttagtat aaagttataa atagatatat
    10621 ttatacttat tttacaatct ttcttcaatt gatatataat atgtttatat aaactaatgt
    10681 atgtgaggtg aaatatgagc aaaaaaacaa aatatttttc tttaattctc tttcctattg
    10741 ctttgctttt aaattttata gccagtaaag ttccaaatat tgttgaaaaa tattactccc
    10801 aattcataga taaaataatt gtacaaatat tgagtaaagt ttctggaatt ttcccatttt
    10861 ctctctatga gattacaatg tacataatag ttatatctac cttcttattt ttatgttgta
    10921 ctttatctac aatttttaat aagaaaaaaa aattaaacat atatttaaaa aattccattt
    10981 taaatatatt atccattgta tcaatagtct actttctttt tgtagtgctt tggggaataa
    11041 actataatag gattccacta gaaaccacac ttataaataa ctataattta aaaaacaata
    11101 cctctatcca atcaaaacaa tatagtgtta aagagcttac taaattatat aaattccttg
    11161 taattaaagc aaatgaaact agaaaactca cattacaaga taaaaatggt attgtaaaat
    11221 ctaatacaga ttataatggt gtcataaata gagctcaact aggatacgat aatatcttgg
    11281 atatattacc tggtgttagt gatagttatt ctaagcctaa gtatattatt tcatcaaatc
    11341 taatgtgcta tacaggaata actggtatat actttccttt tacaggtgag gcaaatgtaa
    11401 atatagcaat acctgactta tatattcctt gtacagttga acatgaaatg gcacatcaaa
    11461 ggggatttgc tagtgaagat gaagctaatt ttatagcgta tcttacttct ataaaacacc
    11521 ccaatattga ttttaactat tctggatata ttttagcttt aaattatact gcttctgctt
    11581 taagtaaggt tgattataat gcatatgttg atatttctgc tggcatttca gattctgtcc
    11641 gtagagattt aaaaaatgaa agtgaatttt ggcaaaaata tgaaggtaaa attaatgaaa
    11701 tttctaatga gtttaacaat tcttacttaa aagctaatgg cgttactgaa ggtactcaga
    11761 gttatggtaa aatggttgat ttattgctaa cttattatga attatatcca tataactaaa
    11821 cactacaatt caaaatttta ttcatataca gctgatatta aatcagctgt tttctattta
    11881 aataaattat ttaacttcaa gcaatcttat ataatttgat agtacttata ctatctgtat
    11941 aacatttcaa ttctaactat tttagttaaa acatttctat tatctttttt aataaatgtt
    12001 ttaactaaaa tttttaaaac ataaaacttc cacattattt cactatctat ataaaaatct
    12061 aaaaattcac atataaaatt acataactaa aaaatcataa atttatagaa aacatatatt
    12121 caaaataaaa aagcatgtat caaaacttga cacatgctta taatcttatg tatatatatc
    12181 attttgtcac aataaaaatt tacttgtaac actgatattt ttaaacaaaa tagtccttat
    12241 ttaattaaat taacattaat taaattcgta ctcattttgc tatcattaaa cattacttat
    12301 agtaattttc taatacacta tttgaaactt ccttcccttg aaaacttttc aaccaattct
    12361 catatgctga gtttttccat acactaccat cattaaatgt tacttgtttt acacaagata
    12421 taatgtactt tacaccatgc tctccagttg attgtttcca tttatcaaac aatagaaagg
    12481 catcattttg attcttacct ggtgctattg cattttgctt tgcatattct ttctccattt
    12541 gtttccattc tttcaaccaa ttttctaccc atgccttgcc ttgttgtttt tcaaacatac
    12601 ttattatatc ctgtggtggt gattgttgca tttttctata agtatgtgaa tatgattttg
    12661 gagacacagg agatatgcct gtaacaatac catagtctac accagctggg ctaaatccaa
    12721 cacttcctac ttcgccatct gctgccacat tttgagcatc ccaatatagc tcaagtggtt
    12781 ttccattttt atcatatgct aagcatgtaa tttcataatc cataattgcc ttttcactgc
    12841 tatttgttaa gcttataaca ttgctaggcc aatgatatgg agtatcatca tactgtattt
    12901 tgctattatt tataaataat ggaatattct cattataaac aagaccttta ctactttgaa
    12961 tatctgatac cttctttgtg acagtactta ccgtatttgc taagtataca tttgtttttt
    13021 ctgaattggt cgtactaaga gaaaatgttg ttgtcgttcc agtaatcagc aaagcaacaa
    13081 ctaaaatagg taagctagat atttttttat atctcacaat tcttcacctc tttttctatt
    13141 aacttataat aaaacaattt accaaaacat taaaatctat gttaacataa tttaccaact
    13201 gttctagtaa ctatatccta tcatagttac tatcaagttt caatactatt gatggaaatt
    13261 ttcactatat taaatctttt tttaatttta taaatttaca atatgattta actcatacat
    13321 atatagtcaa attagaatat aagtttctta catttaatga agtttataaa ataaaaaatg
    13381 actagataat taaatactgt aaataaaaac ttattacaaa agtatttaaa aatctagtca
    13441 tttaatatat atatgaattg tatactataa tttttcaatc tcttctagca actcatcaac
    13501 taatttgtta ccatcaatca ttctaactat ttcacccttt ttaaataaaa gaccttcacc
    13561 tttaccccca gcaataccta tatctgcttc tctggcttca ccaggtccat ttacagcaca
    13621 gcccataatt gcaacagtga tatttttttc catactacca atcttttctt caacctcatt
    13681 tacaacacta attaagtcta tattacatct accacatgta gggcatgata taactttaat
    13741 cttatcattt aaaagtccca aacttcttaa aatctgttta ccaacaataa cctcttcaac
    13801 agggtcgcct gttaaagata ttctaacagt atctccaatt cctttaagaa gaagtgctcc
    13861 tacccctata gaagacttta ttgttccttt gtgaacactt ccagattctg taattccaat
    13921 atgaagagga taatcaactt tttttgatat taattcatat gcatcaacag ttttataaat
    13981 atcggatgat tttagagata taactatatt atgaaaatct aagtcttcaa gaatcttaat
    14041 atgtcccatt gcactttcaa ctaatgcttc agcagttgca gagccatact tttttaaaag
    14101 ttctttctct aaagaacctc cattaactcc aattctaatt tttaaatttc tttccttgca
    14161 tttctcaact accatcttaa ctctctctat acttccaata ttaccaggat ttattcttat
    14221 tccatccaca ccttgttcta tagcttcaag ggctagctta taatcgaaat gtatatctgc
    14281 aataattggt atatttacac tagactttat ctttgctata tttttagcag ctttaatatc
    14341 aggaacagca actctaacta tatcacaacc agcttcctct aatctcttta tttgagctat
    14401 tgtagcatct gcatctcttg tatcagtatt tgtcatagat tgtatactta taggattttc
    14461 tcctcctatt tttacagctc ctacacttac ttctctcgtc tttcttctct cgtaactcat
    14521 attccacctc tatatattat tttatattga atctctttaa atattaaaat attataacct
    14581 acatgtatat tataaattaa aaagctatct agttaaataa gaataaattt catatataaa
    14641 aattaattta ttcttattta aaactacata gcctattttc ttaaaatctc taaaaaacta
    14701 aatcattgaa ataatcttag tatatcttta tatgtgataa aaagcataaa taacattaaa
    14761 gctccaaaac caacaacatt tatcatgcct tctttatttg ggtcgagttt tttaccacct
    14821 ctaacagctt ctagtaacaa cataagtatt ctccatccat caagtgctgg tattggtaat
    14881 agatttacta tacctaaatt taagcttatg acagctgcta aatacactac atttatgatg
    14941 cctgtacgag cagcatctga taccatacca ataacaccta ctggtcctgc tacagcattg
    15001 ccaatccctc ctggtacacg tcctgtaatc atttgaccta gaaatgttag catctgtttt
    15061 gtcatatcta cagtagtttt acatgcattt actattgacc ctaaaaagtc tttttctctt
    15121 tgtggttgaa ttcctatttc atactttcca ttgttatttt taggtgttac atttacaact
    15181 ttatcacttc catctctagt tatactaagt tttaattctc caccagaaga agtgtttatt
    15241 atatttgcaa cttcatccca agtcttaaca gaattaccat taattttatt tatcttatct
    15301 cctacttgaa gccctacagc ctgtgcagga gtatctggca ttatctttcc taatttagtc
    15361 gttggagaac ctatatacaa aaatactgga actaaaagta ttgctgctaa tattatattg
    15421 aatattggtc ctgctacaat agtactaaat ctttgtaata tagacttgtt tccaaaagaa
    15481 tttggactta tttgttcttc atcttcacct tccatgctga catatccacc aattggaagt
    15541 gctcttatag aatactctgt atcttttttt acactatata tcttaggccc catacctata
    15601 gaaaactcat ttactttgat accacttctt tttgcaaata taaaatgtcc taactcatgt
    15661 attaatacaa ttatactaaa tagtattaat gcggctatta tagtcataaa ttcaccttcc
    15721 tattttttta tcagatttgc aacataagct ctactccatc tatctgtttc taagatttct
    15781 tctaatgttg gttcacttat gctactatga acttctaaag tcttctctat gtaatatggt
    15841 atgtcataga aaccaatttt atcctctaaa aattcactta ctaaaacttc atttgctgaa
    15901 tttaaaacag aagaataagt tcctcccatt tttaaacact catatgccaa ttttaaacat
    15961 ggaaaagttt ctaaatctgg ttcttcaaaa gttaaagtac taaattttga aaaattcatt
    16021 ctttcaaagc tactttccat tctatctgga tatgtaagag catactgtat tggtagtctc
    16081 atatctggac atcctaattg agcaattatt gagctatctg tatactgcac cattgaatga
    16141 attatgcttt gtgggtgaac tactacatct atattttctt gttctactcc aaataaccat
    16201 ctagcttcta tcacttcaag tcctttattc ataagcgttg aagaatcaat acttattttt
    16261 cttcccatac tccaatttgg atgcttcaaa gcttcatttt tagttatatt tgcaagttct
    16321 ccctttttct ttcctctaaa tggaccacca gatgctgtaa gtattatctt ttctatattt
    16381 tttttatttt ctccatttag acattgaaat atagcactat gttcactatc aacaggaaga
    16441 atatttacat tgtatttttc tgcttctttc attacaagtt caccagcagt taccaacgtt
    16501 tctttattcg ctaatgctat gtctattccc ttctttatag cacaaagagt tgggactaat
    16561 cctatcatac ctactacagc agttaaaagg acatccactt catcaagtga tgatattatt
    16621 tttaatcctt ccattcctgc taaaacttct atttctatat ttttaggcaa catttctttt
    16681 aattttaatg ctttattttc ctcaaaaact gttacatatt taggtttaaa ctctactatc
    16741 tgttctagca ataattcaat attactgtta gctgatattg caactatctc aaacttatct
    16801 ctatgttctc taaccacatc caaagtttgt ttacctatag agcctgtaga acctaaaatt
    16861 gatatctttt tcatataata atcctttcta ataataaata taccctgtca aaacattata
    16921 acactactaa aacaattatt tttactattc atagaaattt catatattat tccacagatt
    16981 aaaattaatc tattattttt tgtattttgt ggaatattat aaaatattct agtattatta
    17041 aatgcccttt tttatttcca caacatcttc tattttacag tctagtgcta aacatatctt
    17101 ctccattgta tccatagaaa cagatttatc atttcctagt ctgcctaaaa cagaaatact
    17161 tatacctgat atatttacaa attccatttt ctttattttt ctgtcaatta acaatttcca
    17221 taatggagcg tatgaaatca tgttatcacc tcgcaaaata tattctatca cattttatct
    17281 attttggaaa attttcatct atttagataa ataatcacct gcttaagtgt caaataattt
    17341 tatccttcta atatgaaaat ttaatactat actaaatgat tggtatataa cacatatgat
    17401 gcattattat taacatataa aaatttttat tggtgctaaa ttaaagtaat atactattat
    17461 tatatttgca gatatataag aaagatttta ttatatattt aaagtacttg attataataa
    17521 gagacaaggg ctatgatgga tactatag
//
LOCUS       DAMJWC010000078        17369 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMJWC010000078 DAMJWC010000000
VERSION     DAMJWC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17369
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.079"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            115..2178
                     /locus_tag="PC503_003055"
     CDS             115..2178
                     /locus_tag="PC503_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2529020.1"
                     /translation="MTKIILSNYRCFGEEPTTIEINNLTGFIGHNSSGKTALLSALMK
                     LFGEKSSDRIIERSDFHIPESIDPDSISKNELYIEAQFEFPELERGKDSISIPVFFKN
                     MVVSEPGGKPYLRIRLEANWEKSSNPEGSIDSNVYYITSTTEEINPEDKRNIKRYELD
                     QIKMIYVPAIRRPDEQLKNVSGTIISRLLNGISWSEQTKARIKTKASETEEIFFEEKG
                     VESLKKSLETQWNSYHKDIRYSNPKINFNSTDLETILKKVEVTFSPTGTHRDYRVEEL
                     GDGLRSLFYLSLVNTFLEIEEEILKSINDGKEEDIFTLIPPVLTIVAVEEPENHISPH
                     LLGRVVEKLNFISTKENSQTILTSHSPAIVKRIEPTDIRYFRICKEYECTKVKSIILP
                     NEEKEAEQFKFVKESVLAYPELYFAKLVVLGEGDSEEIIIKQMIELKAESVDSSEISI
                     VPLGGRHVNHFWRLLNDLEIPFITLLDLDRERDGGGWGRIKYAIQQLINIGHDKNVLL
                     YTCEGISQDNEFKEMHTWDVTDTENMAKWIEMLKGYDVYFSAPLDIDFAMLQSFKDKY
                     ISALTSAEGPRIKDHGKIQDIVINEDAEDESLKAAYKDRIDSDIKSTLKQEGGDGSTY
                     TEGEKELMIWYSYFFLGRGKPTTHLSLFSNNTDIDFESFPYCLKEFVNSIIEKMIDDS
                     GGGRK"
     gene            2175..4040
                     /locus_tag="PC503_003056"
     CDS             2175..4040
                     /locus_tag="PC503_003056"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024642.1,HMM:NF024754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2529021.1"
                     /translation="MKRNWVSKEDWSPAAGFRLEVEAMNTVINDKNTLVVAGPGAGKT
                     ELLAQRACFLLETNTCRYPKKILAISFKKDAAENLKERLELRCGKELASRFESKTYDA
                     FAKEIVDRFRNSLDEAYRPLNNYNIAENRDVRRAFEIAGLNFRGNQTEFNKVYGNKLS
                     INKLPLHTDFVDKIFIDAWNVLLKGNKDTNFVSSLTFGMISRLAEYLIRTNRYIKKAI
                     EMTYSHVFLDEFQDTKSIQYDLVKACFFKTETIITAVGDGKQRIMLWAGARKSIFEDF
                     QNDFLSQKRTLIMNHRSAPRLVEIQKAMYNSLNEEAIDLKTNEKWNYEDGEVYLRLFE
                     DYIKEADILSEEIVELVETGIEINEICILVKQSVDIYSKEIINKLSERNIKARNEAMY
                     QEILKEDIIKTLVSLFRLSLSDRNPDDWDYIYDILGELYGIDEGYNPKILNDFITKVE
                     LMINDLKVNLNITDEKQFSDLVDSKVEYISYEKFASKFQKYKSKDYFDDLVDKFKKLV
                     WIEYNETKDWIKAIDNFEGKNSIPIMTIHKSKGLEYDTIFFVGLEDSAFWNFKNQPDE
                     DRCAFFVALSRAKRRIDFTFSLDRPAGFSNSQKHYCINEFYELFDNTEIVKKIEY"
     gene            4164..4978
                     /locus_tag="PC503_003057"
                     /pseudo
     CDS             4164..4978
                     /locus_tag="PC503_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728762.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5003..5491
                     /locus_tag="PC503_003058"
     CDS             5003..5491
                     /locus_tag="PC503_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF2529022.1"
                     /translation="MYEKDYKQYIKLDIPIDEAKIKNRFEIRLKNERAYHAAVDLLAN
                     RDEEKTAFSIINRYIRFVDKDDEKIRSEWKTNDQWSYFIGEGRAKLKLTTNPEPYNIQ
                     KTLNWLSRQVAPTLKTIKRLDSLNNSTLIEGLIRYARLTDKHKKIIEQNSVNVEDIIY
                     DE"
     gene            5604..5765
                     /locus_tag="PC503_003059"
     CDS             5604..5765
                     /locus_tag="PC503_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529023.1"
                     /translation="MAIAIIGVYLGFKREFSKLIGFLVVALIAVGLVFNTAGVKDILL
                     ELFNKIIGV"
     gene            6005..6232
                     /locus_tag="PC503_003060"
     CDS             6005..6232
                     /locus_tag="PC503_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529024.1"
                     /translation="MDIVKVFANNVRKYRNKKGLSQEAFAEKAGLHRTYICAIERKKR
                     SIALDNVQKIADALEIETYLLFIEGEEKECL"
     gene            6229..9168
                     /locus_tag="PC503_003061"
     CDS             6229..9168
                     /locus_tag="PC503_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2529025.1"
                     /translation="MKKLPIEKLIENLGFSGSKNLVNIDMLTKLDISKHDVKTLKVIN
                     PYAIYLVNSKPFILFIESSFEEKKLQQISKLIWNAQIPIAFICDSNSVKIFNGKALDL
                     KSYLIEEIYNQSIEDFSEESEFSYLKISDPLFWDQYTKQYTKTHLNDYLLDNITSLTN
                     KLKKKYKVKFATKLVLRLIFIRYLIDRGVDIAYKNFNHDIKASQKELLKITKNKVELY
                     ELFKYLKEKFNGNLFELNDEINNTCLTDEVFILLSDFLSGKISIDNGQMSLFSMYDFN
                     IIPVELISNIYEILLGKEIRNKDNAFYTPNYLAEYILDKTTLEFLKNNRQYKILDPSC
                     GSGVFLVNSFRRIIDMNLGDKLFCEDDKLLKELLLSNIYGIDINEDAIDVTIFSLYLT
                     ILDYKDPKILSEFKLPNLKGCNLIASDFFDDNKLESLKKINFDFIIGNPPWGSVSDGL
                     HLDYCNKNGYNDMQQNKEISRSFIFRAKDFSSRNTVCSFVVHSKILYTQKKPSKKFRE
                     FLLKKSQIFSVVEMSSVRKLVFKNADAPAAVISFKYNESEENLNNRIIYTSLKPNVFF
                     KLFNIIVIEKYDVKYISQKLLLENDWAWKTIVYGFSKDIDIIMNIKKKYQTVNEIILK
                     NSFVHGTGIQINGNESHDATHLKGKWYVDSKKGIDSFYVDINKGKELTQDKMRRPKAN
                     QQEIFIPPYVLLKKGVDTKTYRYRAAFSNDAFVYSDAVTGICGKKDNLTTLYCLTGML
                     NSSFYSYLNIMLGTSIGIEREQGFSTEIFTYPAIESDEIANLVVKIQEATKLEKTTMF
                     LNEKNSCKYIKQLDKLILKSFNLNDDKFIDYAINIQIPELTNSKSTNIYRKITKEDLI
                     NYSECFKEQFSSIYRRVGKSISISVYPKILNRFTVFELEVTDEKTDREIMVKAEADNN
                     MELFTKIIRYDYNDVFHQIRDIIHFGENSFYIIKPNCYKYWHPAIAEMDLADVLDQIL
                     SDTGGEE"
     gene            9168..9842
                     /locus_tag="PC503_003062"
     CDS             9168..9842
                     /locus_tag="PC503_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529026.1"
                     /translation="MGGFKNSSLNFYLKQGLYEIIIDGLIDCCLLMSKSCIEQSRKIL
                     NHEEKIRTHLVENYLENDIERRKTSLSKQHLRFEVEAQENYDNKNESYEGRVDIKVIS
                     KDTLADRRAYYIIECKRIDGKETLNKKYITEGVQRFITEKYSSHYGKNIMLGFIVKDI
                     NIQSNIQKINSLNQNILYTYIDTDMLTVRSDSENNYAVCESKYKVKSKLLLLNHIFYN
                     FSSIIR"
     gene            10003..10419
                     /locus_tag="PC503_003063"
                     /pseudo
     CDS             10003..10419
                     /locus_tag="PC503_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455547.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            10379..12826
                     /locus_tag="PC503_003064"
                     /pseudo
     CDS             10379..12826
                     /locus_tag="PC503_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            12966..13388
                     /locus_tag="PC503_003065"
     CDS             12966..13388
                     /locus_tag="PC503_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529027.1"
                     /translation="MRLEDIIDKESYEEKYDDLTVEIKKLSKEKKTLKASLINEKSIK
                     ARLREFRKILERNELLEKFDRYVFASIVDKVIVGVINEDGIVDPYKITFVYKTSFDDK
                     QDGHKFINKSPLETYSKDNNDNKKKCSYTNNETLRDCS"
     gene            13926..14960
                     /locus_tag="PC503_003066"
     CDS             13926..14960
                     /locus_tag="PC503_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2529028.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            15047..15250
                     /locus_tag="PC503_003067"
     CDS             15047..15250
                     /locus_tag="PC503_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2529029.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            15421..16581
                     /locus_tag="PC503_003068"
     CDS             15421..16581
                     /locus_tag="PC503_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HDF2529030.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            16840..16980
                     /locus_tag="PC503_003069"
     CDS             16840..16980
                     /locus_tag="PC503_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529031.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
BASE COUNT         7115 a         1683 c         3007 g         5564 t
ORIGIN      
        1 tattcgtata ataatagaaa tattttagca taagatgtat aataaaggaa aaaatacaga
       61 attaaaaaac ataagataga taagtggact taggggagag aaattattat gcaattgaca
      121 aaaataattc ttagtaacta taggtgtttt ggagaagaac ctacaactat tgaaattaat
      181 aatttaactg gatttatagg tcataatagc agtggtaaaa ctgctttatt aagtgcactt
      241 atgaaacttt ttggagaaaa gtctagtgat agaattattg aaagatcaga tttccatata
      301 cctgaaagta ttgatccaga tagtatttct aagaatgaat tatatattga agcacaattt
      361 gagtttcctg aattggagag aggtaaagac agcatatcta taccagtatt ttttaaaaat
      421 atggttgtta gtgaaccagg tgggaaacct tatttaagaa ttagacttga agcaaattgg
      481 gagaaaagct caaatcctga aggaagtatt gattcaaatg tatactatat aacatctaca
      541 acagaggaga taaatcctga agataagcgt aatatcaaaa gatatgagct tgatcaaata
      601 aagatgattt atgtacctgc cattaggaga ccagatgaac agttaaaaaa tgtctcagga
      661 acaataattt caagattatt aaatggtata agttggtcag aacaaacaaa ggcaagaatt
      721 aaaacgaaag caagtgaaac ggaggaaatt ttctttgaag aaaaaggggt tgaatcatta
      781 aagaaatcac tcgaaactca atggaatagt tatcataagg atattagata ttctaatcca
      841 aagataaact tcaatagtac tgatttagag acaattttaa aaaaagttga agtaactttt
      901 tcacctacag ggacacatcg agattatcgg gttgaagagc ttggagatgg gttacgttct
      961 ttattttatc tttcacttgt aaatacattt ttagaaattg aagaagaaat tctaaaatct
     1021 attaatgatg gtaaagaaga agatatattt acattaatac cgcctgtatt aacaattgtt
     1081 gcggttgaag aaccagaaaa tcatatttca cctcatcttt taggaagggt agttgaaaaa
     1141 ttaaatttta tttctacaaa agaaaattca cagacaatat tgacatcaca ttcaccagca
     1201 atagtaaaaa gaattgaacc aacagacata aggtatttta ggatttgtaa ggaatatgaa
     1261 tgtacaaaag tgaagtcaat tatattacca aatgaagaaa aggaagcaga acaatttaaa
     1321 tttgtaaagg aatcagtatt agcatatcct gaactttatt ttgcaaaact tgttgtattg
     1381 ggcgaaggtg atagtgaaga gatcattatt aagcagatga ttgaattaaa agcagaatct
     1441 gtagattcat cagaaatttc aatagtacca ttaggtggta ggcatgttaa tcatttttgg
     1501 cgtttattaa atgatttaga aattccattt attactttgt tagatttaga tagagaacga
     1561 gatggaggtg gttggggacg tataaagtat gcaatacaac aattaataaa tattggtcat
     1621 gataagaatg tattacttta tacatgtgaa ggaatttcac aagataatga atttaaagag
     1681 atgcatactt gggatgtaac tgatactgaa aatatggcta aatggattga aatgctaaaa
     1741 ggttatgatg tttatttttc agctccgtta gatatagatt ttgcaatgtt acaaagtttt
     1801 aaagataaat atatttcagc attaacaagt gcggaaggtc ctaggataaa agatcatgga
     1861 aaaatacaag atattgtgat caatgaagat gctgaagatg aatcattgaa agctgcttat
     1921 aaagatagaa tagatagtga tattaaatca accttaaaac aagaaggtgg tgatggatct
     1981 acttatactg agggagagaa agaactaatg atatggtatt catatttctt tttaggaaga
     2041 ggtaaaccaa ctactcattt atctttattt tctaataata ctgatataga ttttgaaagt
     2101 tttccatact gtctaaagga gtttgtaaat agtattattg aaaagatgat agatgattca
     2161 gggggtggaa gaaaatgaag aggaattggg ttagtaaaga agattggagt ccagcggctg
     2221 gattcagact agaagttgaa gcgatgaata cagttattaa tgataagaat acacttgttg
     2281 tagctggtcc tggcgctgga aaaacagagt tattagctca gagagcctgc tttttactag
     2341 agactaatac ctgtagatat cctaaaaaaa tccttgctat tagttttaaa aaggatgctg
     2401 ctgaaaattt aaaagagcgt ttagaattga gatgtgggaa agaattagct tcaagatttg
     2461 aatcaaagac ctatgatgct tttgcaaaag aaatcgtaga tagatttaga aatagtttag
     2521 atgaagcata tagaccttta aataattaca atatagctga aaatcgtgat gttagaagag
     2581 catttgagat agcaggatta aatttcagag gaaatcaaac tgaatttaat aaagtatatg
     2641 gaaataaact atcgataaat aaattgcctt tacatacaga ttttgtagat aagattttta
     2701 tagatgcttg gaatgtacta cttaaaggca acaaagatac taattttgta agttcactta
     2761 cttttggtat gatatcacgt ttagccgaat atttgataag aaccaatagg tatattaaga
     2821 aagcaattga aatgacttat agtcatgtgt ttttagatga gtttcaagat actaaatcta
     2881 ttcaatatga tcttgttaaa gcttgttttt ttaaaacaga aacaataatt actgctgtag
     2941 gggatggcaa acaacgaatt atgttatggg ctggtgctag aaagtcaata tttgaagatt
     3001 ttcaaaatga ttttttaagt caaaaaagaa cattaattat gaatcatcgt tcagcgccaa
     3061 gacttgtaga gattcaaaaa gcaatgtata acagtttgaa tgaagaggca attgatttaa
     3121 aaactaatga aaagtggaat tatgaagatg gagaagtgta tttaagactt tttgaggatt
     3181 atataaaaga agctgatata cttagtgagg aaatagtcga attggtggaa acaggtatag
     3241 aaattaatga aatatgtata ttagtaaaac agagcgtaga tatttattca aaagagatta
     3301 taaataaact ttctgaacgt aatattaagg cgcgtaatga agcaatgtat caggagatat
     3361 taaaagaaga tataataaag acactggttt cgctttttag gttgtcgtta agtgatagaa
     3421 atcccgatga ttgggattat atttacgata ttctaggtga attatatgga atagacgaag
     3481 ggtataaccc taaaatatta aatgatttca ttaccaaagt agaattaatg attaatgatc
     3541 tcaaggtaaa tttaaatatt actgatgaaa aacaattttc agatttagtt gattctaagg
     3601 ttgaatatat ttcatatgaa aaatttgcat caaagtttca aaaatataaa tctaaagatt
     3661 attttgatga tttggtagat aaatttaaaa agctggtatg gattgaatat aatgaaacta
     3721 aagattggat taaagcgatt gataactttg aaggtaaaaa ttcaattcca ataatgacaa
     3781 ttcataaaag taaaggactt gaatatgata ctatcttttt tgttgggtta gaagattcag
     3841 cattttggaa ttttaaaaat caaccagatg aagatagatg tgcatttttt gttgcattat
     3901 caagagctaa aagaagaatt gattttacat ttagcttaga tagaccagca ggattttcga
     3961 attcacagaa gcattattgt attaatgaat tctacgaatt gtttgataat actgagattg
     4021 taaaaaagat agagtattga ttaagatgat aaaaacttta gtatattata ttttaagata
     4081 ttagttatat aagtagacat tgaatttatg tatttgatgt ctatttttta tataaaaata
     4141 tattaaagaa aggatgaatt tgcatgaaga aaaaaacaaa aatatctaaa aagattgtaa
     4201 gttttattat ggtttttata actatagtta ctactatact tacatcatca gtttcagctt
     4261 atgctagcga gttggatatg agtgaacaga caggctttaa ttatttaggt attagtccaa
     4321 ttacaggaaa aaaattaatc ataacattta tcgtatgaag atggataata aaattgtatt
     4381 ttgtgtagag ccaggaatta aaacttcaag tggaggagga tatatatcgg aggagttagg
     4441 agataaattt atatctacaa cacttccaaa ttatcataaa agaaaagctg aaatacttga
     4501 gaaggtaaat agacataata tattaccttc atggaataat gaaaaagttg cagttaaaag
     4561 tggagaaaca attgagttag aagataagaa tggtattatt agagaaatgc aattagaatc
     4621 aaataatact ggaacagata tattacttga agaaaatact ttgaaaatta cagcaaataa
     4681 aaattctaat tcaggagtta ttagttatat aaagattcct aaaaatgagg ttggaatatc
     4741 aatagtttat cgtaagcata actatcaaag cttatcagaa tttcatatgg aaagttcgat
     4801 gagtgcaaat ttaaatataa atgtaatcaa gttaggaatt gttaaagtaa aaaagattga
     4861 tgaaggcaca ggaaaggaat tagcaaatgc aaaacttaga tttgagtatg atggtgatag
     4921 taaagaaatt ataacgggtt ctaatgaaat tgctagtata gaagatatta ttggttgatt
     4981 aaaaagtgaa gtatactttt gtatctatga aaaagactat aagcaatata taaaattaga
     5041 tatacctatt gatgaagcaa aaataaaaaa tagatttgaa ataaggttaa aaaatgaaag
     5101 agcatatcat gcagcagttg atttgttagc aaatagagat gaagaaaaga cagcattttc
     5161 aattattaat cgttatatac gttttgttga taaagatgat gaaaaaatta gaagtgaatg
     5221 gaaaactaat gatcagtgga gttattttat tggtgaaggt agagcgaagt taaaactaac
     5281 aacaaatcca gaaccatata atattcaaaa aactttaaat tggttatcaa gacaagttgc
     5341 accaacgtta aaaacaatta aaaggttaga tagtttgaac aactcaacat taattgaggg
     5401 cttaataagg tatgcaagac taacagataa acataaaaaa ataattgaac aaaattcagt
     5461 aaatgttgaa gacattattt atgatgaata aaaaaatgta attagtattg cagattttaa
     5521 tataaaagaa gggagatata cgaatgaatt ttggtcaaaa tttatataat tagtttttat
     5581 caaatgcaca atcattggta ttaatggcta tagctataat tggtgtatat ttaggattta
     5641 agagagagtt ttcaaaactt ataggatttt tagtagttgc attaattgca gtagggcttg
     5701 tgtttaatac agcaggagtt aaagatatat tattggagct atttaataaa ataataggtg
     5761 tgtaaggatt aaaagagaat agaaaattat gagtatatga tgaagggttc taataagttt
     5821 tattaaaata tatattgaaa gacaagtaga gctatttcga gttattacat gtaatgctaa
     5881 tatatataac tgcattttgg aaattaaata cataattaga aatagcaaat tttataggtg
     5941 acttattaat atgtttactt attgtatact atttgatata tttaatatga ggtgattctt
     6001 gaaaatggac atagtgaaag tttttgctaa caatgtgaga aaatatagaa ataaaaaagg
     6061 tctatcacaa gaagcttttg ctgaaaaagc tggattgcat agaacttata tttgtgctat
     6121 tgaaagaaaa aagagaagta ttgctttaga taatgtgcag aaaattgctg atgcgcttga
     6181 gattgagact tacttactat ttatagaagg tgaggagaaa gaatgtctat gaaaaaatta
     6241 ccaatagaaa agcttataga aaatttaggt ttttcagggt caaagaatct tgtgaatata
     6301 gatatgctta caaaattaga tatatctaaa catgatgtaa aaactttaaa agttataaat
     6361 ccttatgcaa tttatttagt aaatagtaag ccatttatat tatttataga gtcttctttt
     6421 gaagaaaaaa aattacaaca aattagtaag cttatatgga atgctcaaat accaattgct
     6481 tttatatgcg attctaattc tgttaaaata tttaatggaa aagctttgga tttaaagtca
     6541 tatttaattg aggaaatata taatcaatct attgaggatt tttcggaaga atctgagttt
     6601 tcttatttga aaatatctga tccattattt tgggatcaat acactaaaca atataccaaa
     6661 acgcatttaa atgattattt gctagataat attacttcat tgacaaataa attaaagaaa
     6721 aaatataagg tgaaatttgc aacgaagctt gttctaagat taatatttat tagatattta
     6781 atcgatagag gtgtcgatat agcttataaa aattttaatc atgatattaa agcttcacaa
     6841 aaagaactgc taaagattac taaaaacaaa gttgaattat atgaactgtt taaatactta
     6901 aaagaaaagt ttaatggtaa tttatttgag ttaaatgacg aaattaataa tacttgttta
     6961 acagatgaag tgtttatttt actatctgat tttttatcag gtaaaataag tattgacaat
     7021 ggacaaatgt ctttattttc aatgtatgac tttaatatca taccagttga actaattagt
     7081 aatatatacg aaattctttt aggaaaagaa attcgtaata aagataacgc attctatact
     7141 ccgaattact tagcagaata tattttagat aaaacaacac ttgaatttct gaaaaataat
     7201 aggcaataca aaattctaga tccttcttgt ggatcaggag tatttttagt aaatagtttt
     7261 agacgtatta ttgatatgaa tttgggtgat aaactttttt gtgaagatga taaactttta
     7321 aaagaacttt tattatctaa tatttatgga attgatatca atgaagatgc tatcgatgtt
     7381 actattttct cgttatatct aactatttta gattacaaag accctaagat attatcagaa
     7441 tttaaactgc ctaatttaaa agggtgtaat ttaatagcga gtgatttttt tgatgataat
     7501 aaattggaga gtttaaagaa aattaacttt gattttatca ttggaaatcc gccttgggga
     7561 agtgtctcag atggattaca tttagattat tgcaataaaa atggctataa tgatatgcaa
     7621 caaaacaaag aaatcagtag aagttttatt tttagagcaa aagattttag ctctagaaat
     7681 acagtatgtt cttttgtagt gcattctaaa atactatata ctcaaaaaaa gccatcaaaa
     7741 aaattccgtg aatttttgct taaaaaaagt caaatattta gtgtagttga aatgtcatct
     7801 gtaagaaaat tagtgtttaa aaatgcagac gctcctgcag cagttatatc atttaagtat
     7861 aacgaaagtg aagaaaattt aaataataga atcatctata catctttaaa accaaatgta
     7921 ttttttaaat tatttaacat tattgtaatt gaaaaatatg atgttaaata tatttcacaa
     7981 aaactattat tggagaatga ttgggcttgg aaaactattg tgtatggatt cagtaaagat
     8041 atagatataa ttatgaatat caaaaaaaaa tatcaaactg taaatgaaat tattttgaaa
     8101 aacagttttg ttcatggaac agggatacaa atcaatggta atgaaagcca tgatgcgaca
     8161 catttaaaag gaaagtggta tgttgattca aagaaaggaa tagattcatt ctatgttgat
     8221 ataaataaag ggaaagaact tactcaagat aaaatgagaa gacctaaggc taatcagcaa
     8281 gaaatattta ttcctccata tgtattatta aaaaagggag ttgacacgaa aacatataga
     8341 tatagagcag cattttcaaa tgatgcattt gtatattcag atgcagttac aggaatatgt
     8401 ggaaaaaaag ataatttaac tacactttat tgcttgactg gtatgcttaa ctcttctttt
     8461 tactcatact taaatataat gctaggtaca tcaattggaa tagaaagaga acaaggattt
     8521 tcaacggaaa tttttacgta tccagcaata gaaagtgatg aaattgctaa tctggtagta
     8581 aaaatacaag aagcgactaa attagaaaaa acaactatgt tcttgaatga aaaaaatagt
     8641 tgtaagtata tcaaacaatt agataagtta attttgaagt cttttaattt aaatgatgat
     8701 aaatttattg actatgcaat aaatattcaa attcctgagc ttacaaattc taagtcaact
     8761 aacatatata gaaaaataac taaggaagat ttaattaatt atagtgaatg tttcaaagaa
     8821 cagttttcat cgatatatcg tagggttggg aaaagtattt caatttcggt atatccaaaa
     8881 atattaaatc gttttacagt atttgaacta gaagtaacag atgaaaaaac agatagagag
     8941 attatggtta aagcagaagc tgataataat atggagttgt ttacgaaaat aattagatat
     9001 gattataatg atgtttttca tcaaattaga gatattattc attttggaga aaattcattt
     9061 tatatcataa agcctaattg ctataaatat tggcatcctg ctatcgcaga aatggatctt
     9121 gctgatgttt tggatcagat tttatctgat acagggggtg aagaataatg ggaggattta
     9181 aaaattcttc actaaacttt tatttaaagc aagggcttta tgaaataatt atagatggat
     9241 taatagactg ttgtttactt atgagcaaat catgtattga acaatctaga aaaatattaa
     9301 atcacgaaga aaagataaga acgcatttag ttgaaaatta tttagaaaat gatattgaaa
     9361 gaagaaaaac atctttatct aaacaacatc taagatttga agtagaagca caagaaaatt
     9421 atgacaacaa aaatgaatct tatgagggta gggttgatat aaaagttata tctaaagaca
     9481 ctttagcgga tagaagggct tattatatca ttgaatgtaa aaggatagat ggtaaggaaa
     9541 ctttaaataa aaaatatata accgaaggtg tacaacgatt tattactgag aaatattctt
     9601 cgcattatgg caaaaatata atgcttggat ttatagtaaa agatataaat atccagagca
     9661 atatacaaaa aattaattca ctgaatcaga acatattata tacatatata gatacagata
     9721 tgttgacagt tagaagtgat tctgaaaata attatgctgt ttgtgaaagt aaatataaag
     9781 taaaatctaa actactattg ttaaatcata ttttttataa cttttcgagt ataataagat
     9841 aatcttatga atataaaata ttactatgtt aaaattatag tttggttttg ataatattat
     9901 aaaaataagt ttaagaataa aatataaagg aaaaaagggg cgtagcacta ttttttagtg
     9961 tgacagcccc tttaatttta aaatcggtaa ggaggagtgt atttgaaaaa aattaagtca
    10021 tatacaggga ttttgaatgt ggagaaggtt atatatgcaa taaatgattt tcagcttcca
    10081 tttccagtta cttttacgca gatgacatgg tttgtattaa cactttttat aattatatta
    10141 tttggtaagt tacctccatt atttatgata gaaggagcat ttttaaagta tcttggcata
    10201 ccaattttta taacttagtt tatgtctcaa aagacttttg atggaaagaa accatatgga
    10261 tttttaaagt caataatact atattcatta agacctaaaa taacatacgc aggaaaaaac
    10321 attaaattta aaaataaaat tattgatgaa aatataacta tagtaaggag tgaattatat
    10381 gttcccgata aaatatatag agaacaatct tgtatttaat aaggaaggag aatgttttgc
    10441 atattatgaa ttaataccat ataattattc attcttataa gctgaacaaa aatttattgt
    10501 acatgataat tttaggcaat taatatcaca aagtagaaat ggtaaaattc atgcacttca
    10561 aatagccact gaaagttcta taagagttac acaagaaagg ttaaagaaaa atattacagg
    10621 aaaattaaaa gaaattgctt atgaaaaaat agacgagcaa acagaggcac ttgtttctat
    10681 gattggcgat aatcaaattg attatcgttt ttttattggg tttaagcttt tagttacaga
    10741 gaaagaaatg aatataaaga gtataaaaaa gtcaatatta gctaatctat cagattttat
    10801 atatgatgtt aataataaat tgatggatga ctttgtcagt ataaataatg atgaaattat
    10861 gagattttta aaaatggaaa agttattaga aaataaaatc tcaagaagat ttaaagttag
    10921 aaggttagat aaaaatgatt ttggatattt aattgaacat aattatggaa agaaaggcac
    10981 agtttttgaa gattatcaat accatttacc tacaaagaaa cttaaaagag aaacattagt
    11041 aaagaaatac aatcttataa agccaactag atgtcttata gaagagaagc aaagatactt
    11101 aaaaattata catgaggatt cagaaagttt tgtagcttat tttactattg aaattattat
    11161 tggagaaatg aattttccat ctagtgagat attctattat cagcaacaac agtttgcatt
    11221 tcctattgat actagtatga atgtggaaat tgtaacaaat aaaaaggctt taactacagt
    11281 tagaaataag aaaaaagaat taaaagattt agacaatcat gcttggcagt cagggaatga
    11341 aacagtaaca aatgtagtag aagcattaga ggctgtaaat gagcttgtaa ataatttaaa
    11401 tcaaacaaaa gaatcaatgt ataagttaag ctatgtaatt agggtatcag cagatagcat
    11461 tgatgaatta aaacgccgtt gtgatgaagt taaagatttt tatgacgatt taaatataaa
    11521 attagtacgc ctaatgggag atatgatagg atttcacaat gaatttatac cttcaagcaa
    11581 aaggtatata aatgattata ttcaatatgt aactagtgat tttctagcag gattagggtt
    11641 tggagcaact caatagcttg gagagaacga aggaatatat attggatata gtttagatac
    11701 aggaagaaat gtctatcttc aaccatctct tgcaagtcaa ggagtaaaag aatctgtaac
    11761 taatgcgttg gtagcagcat tctttggatt tttaggaggt gggaaatcat ttgctaataa
    11821 cttacttgtt tactattcag tattgtttgg agggcaagct gttttggtgg atccaaaagc
    11881 tgaacgtggc aaatggaaag aaaatttacc agatatatat catgaagtaa atattgttaa
    11941 tttaacaagt gatatagaaa ataagggaat gctagatcct tatgtaatta tgaaagaagt
    12001 aaaagatagt ggaagtctag ctattgatat attaactttt cttacaggaa taagtagtca
    12061 tgatggagag cagtttccta tacttagaaa atcaatcata aatgttactc aagacaaatg
    12121 cagaggactt ttgaaggtaa tagatgaatt aaggaaagat aattctcaaa tatcaaataa
    12181 tattgcagat catattgaaa gttttacaga ttatgatttt gcacaattac ttttctcaga
    12241 tggaaatatt aaaggctcaa ttaatctaga aaaacaaatg aatataatac aagttgcaga
    12301 tcttgtttta ccgaataaag atactttatt tgaagaatat acaacaatgg aaagtctttc
    12361 agtagctatg ttgatagtaa ttagtacttt tgcattagat tttatccata cagatagaag
    12421 tacttttaaa atagtagatt tagatgaagc ttggacattt cttaatgtag cacaaggaaa
    12481 aactttatct aataaattag ttagagcagg atgtgctatg aatgcaggag tgtattttgt
    12541 aactcaaaat gcaggtgatg tatcagatga aaatttaaaa aacaatattg gattaaaatt
    12601 tgcattcaga agcacagata tcaatgaaat taagagaata cttgaatttt ttggagttga
    12661 taaggaagat gagaataatc aaaaaaggtt aagagagtta gagaatggac agtgtttaat
    12721 acaagattta tatggacgag ttggggtaat acaaatacat ctagtttttc aagaactcct
    12781 tactgcattt gatacaagac cacctataag aaaagaggtg gattaatgaa atcgaaagta
    12841 tttagaaatt taagctggat aactatttta atagtagtac ttttactatt ttttatttat
    12901 ataaatttat agatttagag aaacaaatag atacattaga taagaaaaga aaaaaactca
    12961 tagatatgag attagaagat ataattgata aagaatcata tgaagaaaag tatgatgatt
    13021 taacagttga aataaagaaa cttagtaaag agaaaaaaac tcttaaagca tcattaataa
    13081 atgaaaagag tataaaagca agacttagag aatttagaaa gatacttgaa agaaatgaat
    13141 tgttagaaaa atttgataga tatgtatttg caagtatagt agataaggtt atagttggag
    13201 ttattaatga agatggtata gttgatcctt ataaaataac ttttgtttat aaaactagct
    13261 ttgatgataa acaagatgga cataaattta taaataagag tccgttagaa acgtattcaa
    13321 aagataacaa cgataataaa aagaagtgtt catatactaa taatgagaca ttgcgagact
    13381 gtagttaaac ttattagaga ataacaaggt ttcagacttt tatattgtgt cttaaaagta
    13441 gatttgccac ctatttgcca ccataattat ttttgggtgg caaatttatt ctacaatgat
    13501 ttcaaaaata tttaccgtct ggtttctcat gttgttagtt acatgtaaat atgtatccat
    13561 agttgttgaa gttttagcat gtccgagtat atgctggata tcttttatat tagtaccatt
    13621 ttctaataac atagtatcag ggtttttaaa ataaagtgtg tattcttcta aagtagtgat
    13681 aattaaaata tcaaatatca ctatacaaag gaaagtgcac gctttttatg tttaacaaaa
    13741 acgaaatatt aaaaaactta ttgaagaata tgatgtcaaa acaactacag atattcaaga
    13801 tatgctaaaa gatttattta caaatacaat tcatcaaata tttacattgt cgaattttag
    13861 cggtttaaac ataatatatt gactgatata ataaaatcat agaatatttt agggggaaat
    13921 agattatgtt taagaaaaag ttaatagctg ttgcaatgag tataactatg attagtgtag
    13981 ggagcttttc gtatgctcat tcaggaagaa ctgattcatc aggaggtcat cgtgataata
    14041 aaaataaatc tggattagga agttatcact atcattgtgg tggttatcca gctcatttac
    14101 ataataatgg tggttgtcct tatactggag gaggaagcag ttctggaaca acaacttcgg
    14161 ttaataatga agaaaagcaa aagaggtctg ttggagaaaa aggatataat caagggtatg
    14221 aagatgggta taaaggaaat tatagttcat caaattatag tggagattat agtgatacat
    14281 atgaatcaaa gtactcagaa ggatatgaaa aaggtaaggc taaattagaa gaggaagaaa
    14341 aggtggctaa agagactgga tataatttag ggcttacagg tgctaaatct aataatacat
    14401 atgaaaaaga agttttaaaa aatgcttatg ataccggata ttcaactgga tacaatgaat
    14461 ataagactaa aaagatagaa gaatataaag ctaaagggat agaggatagc aataaagata
    14521 aggaaaaaat gacatttgaa gaaaacatag attctgaatt tatagatgct tataataatg
    14581 cttatgacga aatacaagaa caattaaaaa atgattacac tactcaagga tttgagagtg
    14641 ctatcaaagg agaaagattt gacacatcaa ctataggtaa tgttaaatat gctaattggt
    14701 ttaaagaagg atatgataat ggtaaggtta agttacctaa agcaaaagaa agtgtatata
    14761 atcaaggtta caatgaagaa gattttagta taccagatga aatgaagtct attgaaacta
    14821 agttaaaagg tgtatatgat gaaggtttag aaaaaagaga agaagagaaa agtagaaatg
    14881 ctacttatgg ggttggagct ggaacagcag ctgtagttgc tggagtagta tataagaaga
    14941 aaaaacgtaa aaagatatag atgctagata taccaatgat gacaagtgta taacaaatat
    15001 aattttaagt ataaatattt aaaatataga agggaaggtt atatctatgg gatttaactt
    15061 taggaaaagc ataaatctag gaggaggact caaattaaat ttaggtaaga agagtgtagg
    15121 tataagtgct ggtgttaaag gtgctagagt gtcagttaat tcaaaaggaa gaaaatcagc
    15181 tacattgagt atacctggaa ctggaatatc atatacaaaa actagtacaa agaaacgtaa
    15241 acctaaataa atatttgata tactaagaaa tagactgtta caaatagtct attttttagt
    15301 atatagattt aaaaagtgac aaaattttga aatataaact aatttcataa aggaaaatat
    15361 tattttatgt agaattataa tatttaagta atattataaa atttatagga ggatttcatt
    15421 atgaaattaa gcaaaatact attggcaata gggatgtctg tttcattatt gattgctagt
    15481 tgtccaacat caaacgctct tagttctatt aattcaataa aaggtacaaa taagtatgaa
    15541 acagcaggtt taatagcaga taaacaaaat tatgatattg caatacttat taattctgaa
    15601 aatggattat ctgatggatt gtcagcaagt ggattgtcag gagctaaaaa tgccccaata
    15661 ttgttaacta agaaagatac aatcccttca gaaacattaa aaagattaga aaaggtaaaa
    15721 gaagtatatc taattggagg aaaaaattcg ataggagcat cagttcagaa aatattaagt
    15781 gataaaaaaa taagcataaa tagaataagt ggaactgata gaatagatac aagtcataaa
    15841 gttgcaaaag aaataggaag agtaagtacg gttaaaaaag taatattaac taatgctttt
    15901 aaaggcgaac cagatgctat gagtgttgct tctatagcag ttagagataa atctccaata
    15961 gtattaactg atggaaatac tacaagtttt gctacagatg gattagaaac ttatgcaatt
    16021 ggtggaaaag tcagtatgag tgataagtta ataaatgaaa ctaaagcaac aagaataggt
    16081 ggagtagata gatacgatac aaataaacaa ataataaata aattttataa tggctcaaaa
    16141 gaattttaca tagcaagtgg gactgattta gtttattctt tagttggttc tacaattgca
    16201 caaaaaacac ctatagtgtt agttggaaat ggaagtaata agagtatatt aaaaaatgca
    16261 agtaaaataa ctgctattgg aaatattgat gatgttgtta taaaacaatg tttaaatata
    16321 actaataatg ttggggattc aaatacaggt attgtaaaag atactaattc aaataatacg
    16381 aacaaaccaa gtaatgagcc tagctctaat aatcctggat taactgataa aagtacagta
    16441 tatgtaactc ctaatggaaa atcatatcat ctaacaaaaa attgttctac actaaaaaga
    16501 agtaaaacaa taaataaagt aacattaaaa caagctaagt cacaaggtaa aatagatcct
    16561 tgtaatgttt gtgtaaaata atgtattagc caaatatata ttaaaaaaga caattaatta
    16621 agattgtctt ttttattgaa gaaatataaa tttatattat gtattattaa aaaaaaatta
    16681 ttaattataa aaaataataa taaagacgat aagtattaaa attttatgtt tccaatattt
    16741 atgatataat taatatggca aggaataaat atttgaaaaa gctatgagtg gtgtttccat
    16801 ggaagtttct tcactttctt atgagaggag gtgaaaacta tggaaaatct aatgatgagt
    16861 attataactg gtgttatagc cagttacatt tacgataaat taaagagcca ctctgagcga
    16921 ccaactaaga gtggctggga acttaatata aagttccaga aaagtaaatc ttcaaaataa
    16981 tttgttgaag gaaacatcac tcaaagttaa gtaaaatatg tttccttgct tttattatat
    17041 cacaaattaa aaatattaac acaaaatttt gtgaatatat acttattatt gttctaaaaa
    17101 aatatgtaaa taattgattt gattgcatgg aattattgat gtaatattta agttaaatat
    17161 acacaatctc aattaaagaa gataagtact ataaattcat atcaaaaaaa tacataaact
    17221 tttaagttat aattttataa aaagtctttt agtatcatta tttcaagagg aattatcata
    17281 tgaaaaaata acttcattag aaaagtggat aaaaaactgg taagaagatg actaaagatt
    17341 acatatacta ttacttaaat taaaaattt
//
LOCUS       DAMJWC010000079        17307 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMJWC010000079 DAMJWC010000000
VERSION     DAMJWC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.080"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            41..787
                     /locus_tag="PC503_003070"
     CDS             41..787
                     /locus_tag="PC503_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF2529032.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            848..1522
                     /locus_tag="PC503_003071"
     CDS             848..1522
                     /locus_tag="PC503_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2529033.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKAEELADWISEYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            1890..3236
                     /locus_tag="PC503_003072"
     CDS             1890..3236
                     /locus_tag="PC503_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2529034.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNIIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEKAYSIFYGDILESCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3263..4663
                     /locus_tag="PC503_003073"
     CDS             3263..4663
                     /locus_tag="PC503_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2529035.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            4873..6309
                     /locus_tag="PC503_003074"
     CDS             4873..6309
                     /locus_tag="PC503_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2529036.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            6653..7597
                     /locus_tag="PC503_003075"
     CDS             6653..7597
                     /locus_tag="PC503_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF2529037.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7766..8698
                     /locus_tag="PC503_003076"
     CDS             7766..8698
                     /locus_tag="PC503_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF2529038.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            8803..9270
                     /locus_tag="PC503_003077"
     CDS             8803..9270
                     /locus_tag="PC503_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF2529039.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9514..10368)
                     /locus_tag="PC503_003078"
     CDS             complement(9514..10368)
                     /locus_tag="PC503_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDF2529040.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10534..12498
                     /locus_tag="PC503_003079"
     CDS             10534..12498
                     /locus_tag="PC503_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2529041.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSYTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            12498..12959
                     /locus_tag="PC503_003080"
     CDS             12498..12959
                     /locus_tag="PC503_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2529042.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            12962..13282
                     /locus_tag="PC503_003081"
     CDS             12962..13282
                     /locus_tag="PC503_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2529043.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13298..14398
                     /locus_tag="PC503_003082"
     CDS             13298..14398
                     /locus_tag="PC503_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2529044.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14518..17118
                     /locus_tag="PC503_003083"
     CDS             14518..17118
                     /locus_tag="PC503_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF2529045.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLNKSNDAFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTIFTKGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNKMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         6876 a         1783 c         3002 g         5646 t
ORIGIN      
        1 tatttatgaa aaatgtaaac tgtgaaatgg aggtagtaac atgaaaattg aaaatctttc
       61 tattgatgat attaaacgag gctatatatt taatgatgat ttaaattgtt atagttgcat
      121 taaatgtaca aaaacatatg aggtaggaga aatatataaa ataggtaata gattctttga
      181 agcttcaaaa gctattgaac ttcatatgga attagaacat agtgattatt tagagcaatt
      241 gcttaatagt gattcaaaat acaacacatt gactgaaaat caaaaacaat tatttcaatt
      301 atttattagt gatttaccag ataaggagat agcaaaacag gttggagtat ccacatctac
      361 tatacgccat caaaaattta ttttcagaga aaaagcaaaa caggctaagc tctatttagc
      421 actatatgaa tctgtatttg aagataaatc taataaaagt agtactataa taccaatcca
      481 tgaacatgct cgaatggtag atgaaagata tgtagtaact gaagaagaga gaaaacacat
      541 tttggataca tcatttgaaa gtatgaatcc tttaaaatta aaagtatttt cttcaaaaga
      601 aaagaaaaag gtcgtaattt tatctaagat tttggaacaa tttgaacgtg ggaagaaata
      661 ttcagaaaag gaagttaatc agattttaga atctatatat gatgattttg caacaattag
      721 aagatatcta attgagtatg gttttatgag tagaaataaa gaatgtacaa aatattggtt
      781 aacataatta aaataataaa ttttactaat gtgtaatgtt atttttatct agggggagga
      841 gtcaaatatg aatgatgaat taaaatctat tttatacaat aaaggtgtgg acattgttcg
      901 ctttgttgat atatctgaat ttccaataaa tcaaacgcaa ggtttttcta aagcaatttt
      961 attttgtata gggttatcaa aaaaatttat tacagatata tacaataact tacctacaga
     1021 tagtgatgag tttttagaaa aagaggagaa agcagaagaa ttagctgact ggatttcaga
     1081 atatattcaa aataaaggat atagagcgta ttctcaatcg gagaaaaaca atctagaaca
     1141 tggatatttt gaaaaagcct atattaatcc agaaatgcaa tcagggatta gtcctttacc
     1201 acataagaca atagcaaata ttagtggcat tggatttatg ggaaaaaata atttgtttgt
     1261 aacagaggaa tacggatgtg cttttagcat gtgtacagta cttacagatg ctccaatttc
     1321 tgttgaaaga tatcctttga ttgattcaaa atgtatggat tgtaatgttt gtgtagaaaa
     1381 ctgccctgca aaagctatac atggaaatga gtggactttg ccaggaaaaa gagagtctat
     1441 tattgatgtt tcaaagtgtt tttgtgtatt gaagtgtatg atgagttgcc catggtcatt
     1501 aagatatgca aatcaaaaat aattttacta gagaaggtat taaattgaat attataaaat
     1561 ttttaaaatg taagattata taagattttt caaaataaaa atttgtatag aacactcaga
     1621 aatgagtgtt tttttattgg aattaaatta tattgataca aagtttaact attttaatca
     1681 ttatataaaa tttgtattaa aaaattaaga ataacttggt aatagtgaaa atataatgag
     1741 attataattg atttataata taactataat gatgttgtaa aatgaaaatt gtcatttcaa
     1801 aattcccaaa aagagtaaaa gtcacttcgg ttatagtcaa aaaatttttt cagtgaaaag
     1861 aatttagatt taaaagggag gaattaatca tggaaattga aactaaaact ccggattgga
     1921 ttaatgtact agaattaaac agtaaaatag atattactgg gaaatatgat gtaagtaata
     1981 ttatacaaga tattgtctct gataagtcac tagaaggttc cattatatat tttccaaaag
     2041 gtaattattt atttgagaaa ggtattaaaa ttagtcaaca aataacactt caaggagatt
     2101 cttattatgg aggagataat caagtatcaa atttagataa aaaacaatca atcataggaa
     2161 caaccaattt tataactcga ggagtttcta atatgagtat tattgcattg acaggaacaa
     2221 gtcaatgtat caaaaatatt aatttttatt atgatagtca tgatatagag aaaataccgc
     2281 ctaaaaatgt atctgctatt acagaatatg gagaaacaca aggactatct cattttgaac
     2341 acctgtttat ttctggattt tcagggatag ggattgaaat tccatactat tcaactggca
     2401 atgatataat tgttagttca tgtggtcttg gtatgaggct tggagagaag tcaatgcttt
     2461 ctagtagcaa gatttacgaa tgtaaaaatg gaatggagat tactactggt gttagcttaa
     2521 ataatgtgag aatagaagaa ataaaagaaa taggtattaa taataaagga tttggtttta
     2581 acctgattat gaatcttatg gtcgaccaat gtggatattg tggatttatg tttgaaaaaa
     2641 tgtgctatag ccagataact gccagaatta ctagatgcgg tcagtattat aaaagtgttg
     2701 attataatgc ttatgagaat atggaagata gaaaagaaaa agcttattcc attttttatg
     2761 gagatatttt agaaagttgc aatattgtat tgatgaatag aaatattgat accttagaaa
     2821 gtgattcact taatgaacat aagatatatg taatcaaggc aaatgaaaca aacaatgtaa
     2881 tgctaacatg ttatgctgaa gcagataact ttatacaatg tgcaaagggc aacttgctgt
     2941 tagaaaatgg tgaaaatact tataaatttt ataatggtga gatttgttct gtaggaggtg
     3001 ttcaaatttc tgatatagat gaaaaagatt taatcaaaat aatagagaac actttgtata
     3061 tagatgataa aggtaagtat ttaatggttc ctagattaaa aaagaatact gtaatatatt
     3121 cagtactaga ttctacagaa gaaataaata aattacatgg tggaatatgg gaacagattg
     3181 atgtaaaagt attagctggg gaatccatgt actattataa aaagataaaa gattaaatta
     3241 tcaaactagg aggtagtgat taatggaaga gtctataata attaaagata taagtggctg
     3301 gattaatgta cttgattatg gaatttgtaa tgatgaaaca aaagatgtaa gttttaagtt
     3361 gcaagagatt atggatgctg taccagaaga ttctattata tattttccaa aaggaaaata
     3421 cttatttgaa agtggtgtta agattaagaa acgattaacc ttatgtggag attcttatat
     3481 tttagcgaat gttcctaaaa atactgctgg agtaacacag tttactttta aaggaaagaa
     3541 aaatcctaaa agtgaaaata gagcaatcat aacagcaaaa agtgtaagac actgtattaa
     3601 gaacatttgc ttttattcag atagttgtga tagagatatg acatctaatc atgaacctcc
     3661 aacagatgga aaacctagat ttcatcataa tgtaattata aattatagaa atatatctgc
     3721 tgttatatgt gaagataaac agggagaacc aggtcattat gaaaatctat cttttagtgg
     3781 tttttctgga attgcacttg atatgcctaa taattctaca gcaaatgata ttacaatttt
     3841 tacatccgga cttggaatta gtacagggga aaattcaaca attgctaaca gtaaggtttg
     3901 gggctgtgtt gatggaatga taatttctac tggaactttt ataaatggta tgagggtaga
     3961 agaaataaaa aaagttggaa ttaaaaatat tggtagaggt ttaaatttta ttacaaatat
     4021 cacaattgac caatgtggat attgtggagt ttggtttgat tctatatcca atgttcagat
     4081 atcaggaaat atcacaaggt gtgggcagta ctattatgat gtaagctatg ataattattt
     4141 aatgttggat aatagagtta aagaagcata ttctttattc tatggtaatt tattggagtc
     4201 aagtaatata gttttatcaa ataccaatga agataattgg gaagatttca aagaagataa
     4261 gcataaggtg tatcttatag aagcacttaa aaccaagaat gtactattaa catgcaatat
     4321 agatgctact gactggattg ttaagtcaga aaaaggaaat ttaacgtaca ataatatgcg
     4381 acaaactgtt atattttacg atggaaaact aagtagtatc aatggaattg gtatatctga
     4441 tgaagattat ggggataaag tcaagataaa aaaaggaaat atatatataa atagtaatga
     4501 taaggatatt aagatgcata aaccagaggt aggtgacatt atgtcaacaa ttattaaaga
     4561 taaaagtatt ctttctgctc attatggggg aacatgggag aaaattggtg aaaaaataga
     4621 gtttggaata actgtacact attataaatt gatagagaaa taagtaaata cgtagtattt
     4681 gaatagatgt attttattgg agagttagga ctatagtttt aatataaatg gtttggtaat
     4741 agcatggatt gaataatata aaaataatat aaaaaattaa tttgattatg taaatttcta
     4801 tgaagtagta aaactgtgac tttagtcata ggaggttcaa actaagtaaa agggaaagga
     4861 atatataata ttatggaagg aagaactggg attaaagatg gaagatggat taatgtagta
     4921 gaaagaggta ttaaaaatga tggttcgtac aacataggtc ctgctttgca ggatattatt
     4981 gatgaaatag aaacagattt ttgtgtctta tattttccaa aaggtaaata cctatttaca
     5041 agtggtgtta aaattaataa agaaattgta ttgcaaggtg attctaattc atctacaggt
     5101 actacacaat ttataactcg tggagtagaa aatatgagta ttattacatt gacagggaag
     5161 aaacaatgta ttaaaaatat aaatttctat tctgatagtt gtgagataca ggtaaataaa
     5221 gaaccaccga caaaaggtaa tcctaaatat cattatgaga tgattattaa taagaatgaa
     5281 aagaatgttg agatgaataa tgtatcagca atcctgtatg ataacagtaa gaatatgatt
     5341 aaaggtctag gtcattatga aaatatttat ataagtggtt tttcgggtac aggaattagg
     5401 ataccatatt actcaattgt aaatgatatt acagtttcat cttgtgggct gggtattgat
     5461 acaggaatag acacaattat ttctaatagt agaatatcta agtgtcaaaa tggaatgagg
     5521 attagaactg gaactagtat aaataatgta aggattgaaa aaatacagaa agttggtctt
     5581 ataagtagtc aagttaaggg gtatgagggg tatggaagtt ataaaattaa taatattacg
     5641 attgaccaat gtgggtattg tggcttttca tttgattcaa tgaaagatag ttatttttct
     5701 ggtattataa gaaggtgtgg tcagtattat tataatacag attatgacac atatttaagt
     5761 attaaagata gagtagaaga agcatattct ttattttatg gaaattattt tacagaatgt
     5821 aatattgatt tagttagtga taataaggat aactgggatg atggcttaga atataaacat
     5881 aaagtttatg tatttaaaac ccttcaaata ccaaaattaa cattgagatg caatatagat
     5941 gcctatgatt atatcgttaa atcggtacat ggaggaggta atttaatgtt aaaaaataac
     6001 tttaacaatt atatatttat tgattcatct aatccagaag ttattaatgg aattaatttt
     6061 aattatcaaa agaatggaaa cttgttaagg ttaaataatg gtaaattaag ttataaaaat
     6121 ggaaaggaag aaacagctat attcagacct aattatggtc ttattgtagc atcaacagat
     6181 tcagaatgtg aacaaataga ggctacctat ggagaaaaat gggagaagct tggttctgaa
     6241 gtaattggag aagaaacggt atattattat aaacatcatg aaccagataa aacaaaccaa
     6301 atacaataaa atttgtatta tataatgata taaagtttta atatatagtg tttaccttta
     6361 atgtaatatt ggtatatttg tatagtatta aatttgttaa aaagtaaaat tgtagggtgc
     6421 ttgaaaatag cacctttttt agtttcatta taaaattagt tttgaaagtt taggaataat
     6481 gtatatttat ttttaaagaa ttataacctt attaaggata ttttaaatgc tagaaatgaa
     6541 tcagtaaatc atactggaat tatcttaaat gttttgatta aattaagtat ttagagctat
     6601 aattatatta aaaatatatt agaacataat tatattacta tggaggttaa atatgatagt
     6661 aagtgtgagt agaagaactg atatacctgc tttctatagt aagtggtttt ttaacagact
     6721 tgaagaaggt tttgtttatg taattaatcc aatgaatcca aaacaggtta gtaagataga
     6781 gttaaatcca catactgttg attgttttgt attttggaca aaggatgtaa ctccaatgtt
     6841 atatgattta aataaattaa gagactataa atattatttt cactatacta taacatcata
     6901 tggaaaagaa gtagagacat gtattttaga taaaagaaag gtaatagatt catttaagga
     6961 attgtctaga aaaataggca aagaaagagt aattttaaga tacgacccga ttttcttaag
     7021 tgaaaagtac acagtagatt atcatatcaa agcatttgcg agtttatgta atcagcttga
     7081 tggatttaca gaaaaatgta taataagttt tatcgatttg tataagaaaa caaaatttaa
     7141 tactaaagca ttacatataa agccaataga aattacagaa atagaaacat tatcaaaaga
     7201 gatttctaag attgctcata agcatgggat aatacttgaa atgtgttctg aagaatataa
     7261 tttaagtaaa tttgggattg gaaaaagtaa gtgtattgat gatagattaa tatcaaaaat
     7321 tataggatgt gaagtagagg taaaaaaaga tagtacacaa agagatattt gtggatgtgt
     7381 taaaagtgtc gatataggac aatacaatac ttgcagacat tattgtctgt attgttatgc
     7441 taactttaat tatgcaaaag tagaagaaaa ctgtaggctt tataaggaag ataataaatt
     7501 actcatagat actttaagag atgatgcaaa aataagcatt agagatatga agactattaa
     7561 agtagataag aataaacaaa ttagtatatt tgattaaaat aaatatacta attaccttaa
     7621 tatattaaga atatagatac ttttgataac aaaattaaac ttaatagata ttttctatat
     7681 aagaaagatg gtcataatat gtcaatttga ccatcttttt gatataatta aaacacaaat
     7741 aatttagtaa caaaggaggc agaacttgaa tttattaaaa aaatatccta tacctattgc
     7801 aagtttgatt ttatcaattt ttactttagg taacttatta caatcttata gtgaatcatt
     7861 acgtaatgta attggattta taggatttat tttgtatgca atttatatag tcaaaataat
     7921 attacttaga aagggtgtta aagagcaatt agagaaccct ttaatatcaa gtacatttcc
     7981 aactataaca atggcaacaa tgatatttgc tacatatata aaaccattat ctttagaatt
     8041 aagtattatg atttggagca taggaattgt gggtcatctt gtgttaatag tcttatttag
     8101 taagaagttc ttagttaaat tctcaataaa aacggtattt ccatcttggt atatagtata
     8161 tgttgggata gttgcagcta gtgttacggc accagcattt aatcaacttt tgattggcaa
     8221 aattgccttt tggataggat ttgtatctta tatagttctt ataccagtaa ttttaaagag
     8281 agtatggata atcaaggaaa tgcctgaacc atccttacca agtatagcta tattagctgc
     8341 accagggtca ctattattgt ctggatatat taattctttt tcagataaaa ataatgtagt
     8401 attatacttg ttattcatat tatcaattgt attttatatt atagttttgg gatatttacc
     8461 gaaattatta aggttgcctt tttatccgag ttttgctgca tttacattcc ctatggcaat
     8521 aagtgcaatg ggtatgaaac taatgaatgg ttatttaact aaatcaggtc attttataag
     8581 ttggatttca tatgcttcta agttagaaga gataattgct acagtgatta ttttatatgt
     8641 tttagttttg tttattatat atcttagtaa atctgaaact acatctaaag ctaaataaga
     8701 attattaaat atgtgtattt aataggaata ttgatataaa tatatgaaga taagataaac
     8761 catagaaact taatttagct taattttatt ggaggaaaac aaatgaaaac aaaagaagaa
     8821 tatttaaaag aagttagaaa catatcagaa gaatacttta gaaaaggaga gtttttttgc
     8881 tctgaagcag ttctccagac aataaatgat gctttaggcc aacctttaag tccagagata
     8941 actaagttag catcaggatt tccgatagga cttggaaagg cacaatgtct ttgtggagca
     9001 atatctgggg gagagatggc tttaggtata gtatatggaa gagttcatgg tgaagctatg
     9061 aatccaaaga tgtttgagca tgctaaaggt ttgcatgatt atattaaaaa agagtatggt
     9121 gcaacatgtt gtagagctat tacaaagaaa tgggatggtg ataactttat gtctcccgaa
     9181 agaaaagagc actgtattaa aataacaggt caagttacag agtgggttgc agataagctt
     9241 atagaagatg aaaaacttaa tatcaaatag tgtaatatta gttggtgaat ttataaagtt
     9301 aaatttactt atagtataag atacttgata ttctcgtatt gatagaaaaa tttatagcat
     9361 atgtatttaa tgaaatatac ttatatttag agtgtggttt aatttcataa atacatatgc
     9421 tattatttta agtatataag caaatttatt taaataaata gaaacagtta atttatatgt
     9481 acaaaactat atatgattag tgtaaataaa tacctatttt ataatactca acataaagac
     9541 accagacatg attagtatta taccaataaa aatagcaagc cattcttttt tgttcttctt
     9601 ttctttaaaa aatataatcc ctcctaaagt ggctactatc acacaactct gagagataga
     9661 aaaacttatt gtaactccca atgtattagt cgttatgaac atacctaaat ttgctattga
     9721 ccacaatata ccagtaatta aattgaataa aacattttcc ctatatacaa tctctttaga
     9781 aaaatacttg acaataatag atgaagttat caacatacca acagattgag gtaatataat
     9841 tctatatcct tcaattaaaa atatttgatt agttacaaca tataatgata aaaatagaga
     9901 tgataataat acaactccaa cacattttaa catattttta tctgtagatt ttttagtttg
     9961 ataatttgtg agaagtatac caagtattat acataatatt gataaagaac caatcagtaa
    10021 cattttagaa ctggtccatt cattaaacaa gattacagct aataatgtcg taaaagttaa
    10081 ttgtgaacca tttgaaattg gcattacttt agatacacta gcaatttgaa ttgctttaaa
    10141 ctgcattaat tgtcccaaac tccagaatat gccagaaatc atacttatac aaaatgaaaa
    10201 aaatgtaatt tcaggatgta taaccagagt tattatagtg gaaaatataa acgcacttat
    10261 ggatgtacct aaaagctgtt catgaggaga acttttcttt agatttgcaa ctatgggcat
    10321 caatccccat cccattacag gaagtaaagc aataattatt gtcagcatta aactatttcc
    10381 tttcatatta aatttagaca gcttttaatt tatcatctaa aattaaagtg ttcaatacat
    10441 aaaaattacc gtatttaatc aggaaatatt agtagttttt tagaaaaaca ttttccatta
    10501 aaataaagac aaagggaagg agtaaaattg aaaatgttaa ctgatatgat tcaaaatcgt
    10561 gaaattaaaa taataaagtt tttattaaaa gaaggtcata caactgtaaa agcaatagca
    10621 gatgatttag atgtttcaga aaaaacagtt tcaaaatctc ttaaagaagt agaagcagtg
    10681 cttaaaaaga taggtctttc tttaataaga aaacctaaga taggtgttta tattgatgga
    10741 gatttaaaaa aaatacttcc ttacctagat aataaaggaa gtcaaattcc tacaaccaga
    10801 gaggagagag ttatctatat atattcagta cttttaaaga gtaatgatta tattactata
    10861 caacaacttt ctgatgaact atatataagt cgtggaacta ttgaaaggga tttagcagaa
    10921 gttgaaaaac tgctaaaaaa cgaagggatt tccatatata agaaacctag taagggaata
    10981 aagttaaata taagtgaaag agataaaaga caacttactg ctaagtttat acataaattt
    11041 tggagtagaa actggtatat taagcaagag caagaaagct tttatcaagc atttgaaaag
    11101 atacaagcag atgtaaatgg tattttttcg gaagatgatt tatcaataat tattgatatt
    11161 cttaggaatt tcagcagaga aagaaaattt gagttctctg attatgaatt tcagtcatta
    11221 gttattcatt tggcaatagc tgtagagaga attagaaaag gcgaatatat agaagaaagt
    11281 ttgtatactg gtaatataga aaataatcaa atgtcaaata ccaattattt agcaaaacaa
    11341 ttagaagaaa aattttcaat attattacca aaatctgaaa ttggatatat aaatttacat
    11401 ttagtagcgt ctgaccaaca tagagatact aatgaactaa aaaatacttc aactaatcct
    11461 tgtgagacaa gtacaaataa tatatcaaat cttcgggaaa ttataaaaaa tacattgtat
    11521 gagacagctt atgacaagga tttaattgat ggattaactt cacatgtaca ttcatcaata
    11581 aatagactga aatatggact tagtattaaa aatccatatg taaatacaat caaacaaaac
    11641 ttttctttat catttgagca agctttagat ttaaagaaag taattgaatt tatatatgat
    11701 attaggataa atgatgatga atgtgcttat atagcattac attttgaagc ttttagagaa
    11761 agaatgaaag aacttccaca aaatattaga gtaattctag tatgcagtac aggattaggt
    11821 tcatctaggt tattgtctgc aagaataaaa aaatactttc caatgataaa gattgaaaaa
    11881 gtactttccg tacaagaatt agtatccagt aaaattgatg cagatttagt aataagtact
    11941 atttatttag agttagaaac aattccaacc atagtagtta gtcctatttt aaatgaaagt
    12001 gatataagaa ccttggaaag aaatatacaa aatgtttcaa gttatacttc taagaagtat
    12061 aaatctttca gaaacttaat ctttgaagaa aatatattgt tgaatattga agcttcaaac
    12121 tatgaagatg caattaagta tataacagat aacctaataa aaaaaggttt tgcaaaagaa
    12181 ggtatagcta aaagtgcaat tgagagagaa aatttatctt acacttcttt ccaatcaata
    12241 gctacacctc atgctaatcc tagttatatt aaaaaatcta atatatctgt tgcaacgtta
    12301 aaaaatccta ttacatgggg aaatgaaaag gtggaagtta ttttctttat ttcattagaa
    12361 aatgacaaaa acctagagct tgatgaaata tatgaagttt tttatgactt cattgacaat
    12421 aaaaaaaata taaatgacat attaagtgca acttccacaa aggaagtgta cgatttgcta
    12481 gtggaggaga gtatatagtg aaaatatcag atgtattgaa aaaagagcaa attgttttta
    12541 atcttgatac aaatacaaag gaagaaacaa taaaaaaatt aagtagtata tttgttgaaa
    12601 atgggattgt ggacaatgaa gaagaatatg ttaagtctgt tttggaaaga gaagaacatt
    12661 caactacagg tattggtaat ggtattgcta ttcctcatgg gaaaagtaat gctgtcaaaa
    12721 aatcttctat aatatttgca aagactaagc ataagattga atgggatgct ttagatgaaa
    12781 aaccagtaga tagtattttc ttattggcta taagcaatat tgataaggat agcaatcatc
    12841 ttgtactatt atctaaatta gcaactaaac ttatggatga tgacaatgta gatgcactaa
    12901 aattagccaa ttcagaacaa gaaataatca atatatttag tgaagaagga gagatgtaga
    12961 aatgaaaaga aaaattatag cagttacagc atgtgcaaca ggagttgcac atacatatat
    13021 ggcagctcaa gcgttaaaga aagcttcaaa aaagatgggt caccttataa aagttgaaac
    13081 acaaggagct acaggaatcg ataatgagtt aactacaaag gatgcacaaa ttgcagaagt
    13141 agtaatattt gcagtagata ctaaagtcag aaatgctgaa cgttttgagg gaaaagaaat
    13201 actagaagta ccagttaatg cacctataaa ggatgcagag aaagtaataa atgatgcact
    13261 aaagttaatt gacactaaat aaatggaggg aaatgtaatg ttgaaaaaga tagtctctga
    13321 gttaaaaaag catgtcttaa ctggaatctc atatatgatt ccattagtaa ttgcaggtgc
    13381 tatgataatg gcgatatctc gtgtaggtgg ttctttctat aatataccag atatatggga
    13441 tgctaaatat gcagaaagtg ctagtagtat tgttagatta ttacatgatt tagatgggtt
    13501 tggaggtact gcattaggat taatgtttcc tgtaattgct gcatttatag gattttctat
    13561 agctgataaa ttagctattg taccaggtct tgttggaggt atgattgcta aagatatagg
    13621 tgcaggattt ttaggagctt tggcagttgg tcttatagca ggatatacat gtttgtttat
    13681 taaaaatcat gttaaattac caaaatcagc agcttcaata gtaccaatat ttatagtacc
    13741 agtatttggg acattaatca ctgttgtatt aatcaattat gtgataggta taccttttgc
    13801 cacattaaat actggattag aaaattggtt aaatggatta tctggtacaa atcagatact
    13861 aatggcagct attatagggg ctatgatggc agttgactta ggtggaccag ttaataaagc
    13921 agctttaaca acatcacttg cattattaac aagtggaatt tatgcgccta acactgctgc
    13981 aatggtagga atagttatac caccactagg attgggactt gctactatac tagcaaaaca
    14041 aaaatataat aaacagttac gtgaagctgg aaaatcatct cttataatgg gtttaattgg
    14101 agtaagtgaa ggagcaattc cttttgcggt agaatctcca ttaaaagtaa taccttcatg
    14161 tgtaattgga acagcaattg cttcagctat ggcagttggt ttaggttcag taaatgcaac
    14221 tccaattagt ggattttatg gatggtttac agtagagaat tggccaatgt atgtgttatc
    14281 aatagcagtt ggaacagtaa ttgtagctgg attagttata gtattgcgtg gaaatccagt
    14341 gattgaggat gatgaatttg aagatgatga ttttgatgaa gcagagtggg aatcttaaaa
    14401 tttaataact atttaagacg tgttataagc tatattcaat atgaatctta tactaaataa
    14461 agtgttaaac attcagttta gacttaaata taaaagataa agaacagagg agaataaatg
    14521 ataaaagcac atattgttaa tcatacacac tgggatagag aatggtattt tacttctgga
    14581 gatgcattag tacttagtga acaactattt acagatgtaa ttgatgaatt agaacgtaat
    14641 ccagatgtaa gttttgtact tgatggacaa ctttctattt tggatgatta tgtacaatta
    14701 cacaaagaaa aaatagaaat cattaaaaag ttaataaaag aagatagact acatattgga
    14761 ccatggttta ctcaaactga tgcattcttt gctagaggag agtctatttt aagaaactta
    14821 atgattggaa tttttgaaag taaaaagtat ggtaagtata tgaaaattgg gtatttgcca
    14881 gatacatttg gatttaatgc acagatgcct atactattaa agcatgtagg tcttgataat
    14941 atattctttt ggagaggtat acatcttggt aaacaggttc aatcaccata ttttaagtgg
    15001 aaaagcttaa atggagaaag ttatatatat gcagtaaata tgccacatgg atatggaact
    15061 ggtatgcttt tagagccttc attaaagtat gttaatggac gcttagaccc agctattgat
    15121 tttattaaat catatactga tgtagatgag gtgttaatac cttctgggaa tgaccagtta
    15181 aatataatag gtgatttcaa aaataaaatt aaagcgatta atgatatcgg aaagtattca
    15241 tatataacga gttcatatca agagttttta aaatatataa agtccataga atcactagaa
    15301 agctatagag gagaatttag agaacctgta ttagcaagaa tacataaatc aattggttct
    15361 agtagaatgg atataaaatt agcatgtgat aaactagaaa acaagctgat taaaagaata
    15421 gagccattat tagtaattgc taaaaagagt aaaattgaaa taagcaatca gttacttata
    15481 aatacatgga aaaaactttt ggaaggacaa gcacacgata gtttagctgg atgtgtaact
    15541 gatactgtaa cagatgatat tcttcaccgt ataagagaag caaatgaaat atgtgacagt
    15601 attgaaaata ctattgtaaa aaagatttca gaagggctta aattatctaa aaatgatatt
    15661 ttagtattta atacagaagc taagcgtttt aatggatata aagagataca agttgtaagt
    15721 gatagtaaaa atatttattt taaagataat ttagatgcta ctataattga agaaacttat
    15781 gtaaaaccga gagaaaatgt attagaagaa acacctgctg gtaatatatt tattgaagaa
    15841 ccaggatatt atatattaaa agtaagaata aatgtacagc ttcctgcact tggttataaa
    15901 gttgttagtt ttgaatcaag tgataaagaa atggtgtcac ttaataaatc taatgatgct
    15961 tttatatcta atgataatta taagataata tatgaagatg gaagcttaaa tttacaactt
    16021 aaagatggaa cttacatatc aaacttttta acattaaaag atagtggtaa tgcaggtgat
    16081 acctatgact tttctccact aaaaaatgat gaggatataa aactttcgtt tgataaagtg
    16141 tatacagaaa aagctttagg atatgaaaaa atggtggtta aaggtactac tttactacca
    16201 cttacgttag aagatagaaa aaacaaatat cttaatggga aattaaatgt aaaagtaagt
    16261 attgtcttat ccaaagaaaa tccattgatg gatgtaaaac tttgtgttga taatacgata
    16321 tataatcata gactacgtgt tcatataaaa actgatataa aagataataa aaacatagca
    16381 tcattgccat ttggatatat aacaagagaa aatggagttt tagacaactg ggaagatatt
    16441 tacagtgaaa tgcctataga tttagaacct ttggaaagta atattactct aacaaaccaa
    16501 aatagaagct gtactatatt tactaaagga ataaaagagt atcaacatat tgaagatgaa
    16561 attgcattga ccttacttgc tactacagat gaactaggaa agcctgattt attatataga
    16621 ccaggacgtg cttctggtga tacaactaaa aaaggtcaca taagaattaa aacagataaa
    16681 gctcaaatgc ttaagaaatt agaattttca tttgcaatat atatggattc taaatcattt
    16741 gatgaattgg aaattgcgaa tttaacccac aattatctaa gggaatgtgt aaattatcaa
    16801 ttacaggatt acaatttctt tttatatcgt atagataata agattcaaaa atcaattgtc
    16861 aataaaactg taagtagaga attagaaata atatctttac cagaaaacta tcttatatca
    16921 gcatgttatc cttcttatta cagtaaagat aaatttataa taagagtgga aaatccaagt
    16981 agtaataaaa tgatattgga tgagcaaata tttaaaaata gaaatgggaa aattgtaaat
    17041 gcaatagaag atgtagaaga ggaacaggta tatgaaatag caccttttga cgttatttca
    17101 atattattgg atttataagt gtaaaagtaa gtttattgtt taaagtctga cagatattaa
    17161 tctgccagac tttttaattt gtataaattt gggtaaatat taatgaatgg ttttagtatt
    17221 taagtatgaa tttagtattt aatatagaat ttattgaagt agaataatta gtttaacagg
    17281 ataagcagtt taaataaaga attatta
//
LOCUS       DAMJWC010000080        16477 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMJWC010000080 DAMJWC010000000
VERSION     DAMJWC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16477
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.081"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            179..2038
                     /locus_tag="PC503_003084"
     CDS             179..2038
                     /locus_tag="PC503_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2529046.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2330..2929)
                     /locus_tag="PC503_003085"
     CDS             complement(2330..2929)
                     /locus_tag="PC503_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2529047.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3032..3829)
                     /locus_tag="PC503_003086"
     CDS             complement(3032..3829)
                     /locus_tag="PC503_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2529048.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3942..4047)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4139..5125)
                     /locus_tag="PC503_003087"
     CDS             complement(4139..5125)
                     /locus_tag="PC503_003087"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2529049.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5609..7339
                     /locus_tag="PC503_003088"
     CDS             5609..7339
                     /locus_tag="PC503_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2529050.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLSIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7449..7529
                     /locus_tag="PC503_003089"
     tRNA            7449..7529
                     /locus_tag="PC503_003089"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7483..7485,aa:Leu,seq:tag)
     gene            7864..8379
                     /locus_tag="PC503_003090"
     CDS             7864..8379
                     /locus_tag="PC503_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HDF2529051.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8871..8975
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9185..11659
                     /gene="gcvPA"
                     /locus_tag="PC503_003091"
     CDS             9185..11659
                     /gene="gcvPA"
                     /locus_tag="PC503_003091"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF2529052.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11659..13116
                     /gene="gcvPB"
                     /locus_tag="PC503_003092"
     CDS             11659..13116
                     /gene="gcvPB"
                     /locus_tag="PC503_003092"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF2529053.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13539..15896
                     /locus_tag="PC503_003093"
     CDS             13539..15896
                     /locus_tag="PC503_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF2529054.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(15982..16299)
                     /locus_tag="PC503_003094"
     CDS             complement(15982..16299)
                     /locus_tag="PC503_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF2529055.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6219 a         1921 c         2694 g         5643 t
ORIGIN      
        1 tatattagaa aaaaattttt gtatatataa aggactctaa agatgaacta tgtaaaacaa
       61 ggtttatata ttctaattgt atagaaaaat ttattgtaaa cgcatgtata ttattagaaa
      121 aaatagtttg gaggtattca ataaacataa aaaacaatat aggggataaa ggtgttttat
      181 gaagagattt ttgaggagaa ttatcttagt tttatttatt ttgttgattt ttataagttt
      241 tatttctatt aaattaattc ataatgttgg agattatgga aaattgatta attatgttgg
      301 gattgttcgt ggagctagcc aacgtctaac taaactagag atgaatcatc aaccaaatga
      361 tgaattaata gaatatattg atgaaatcct acaggagttg attacagggc atggagatta
      421 tggtttagta atcactgatt gtaatgaata caatgaggac ttacttttat tagaaaaaaa
      481 gtgggaagat ttaaatattg aaattaaaaa agtaagaatg aaagaacaga ataaccagtt
      541 attaagtata agtgaagagt ttttttctct tgcaaatgat acagtgttta aaatagaaaa
      601 cttttctaaa gaaaaaagta attacttaat gactttaata ataattatat ctattatagg
      661 tatattagca tgtatcatat tgattttaca atatagtaaa aaaatggtta gactggaaaa
      721 attaaatgta gatttaaaaa atattgcata taaagatgaa ctaacaggag taaatactat
      781 agaaaaattt aaattggatg caaatcaaaa tatttgtata cataaggata agaaatttgc
      841 tgtattctat attgattttg aaaactttaa atacattaat gatatatttg gatatgatta
      901 tggtgacatg atactgaaaa gatatgctaa tcttatgatg aatgacatag ggaaatatga
      961 aatatttgca agagaaattg cagatagatt tgttgcgtta agatgctatg tagataagga
     1021 agatttagtg gtaagacaac gagatgtaga caatgaacta attaatataa caaatgaaat
     1081 taaaaataaa catagtatta ctgttgttag tggaatttgt tgtattgaag atgtaaatga
     1141 aaaattaagt atagatggtt taataaatag agcaaatttt gcacaaaaaa ctgttaagaa
     1201 taaaccaggt actaattatg ctttttataa tgacagtatt cgtaaaaaaa tgattgaaga
     1261 aaatactatc aaaagtagaa tacatgaagc tattgaaaaa agagaattta tagtttattt
     1321 acagcctaaa gttaatttac atagtcaaaa aataaattgt gcagaagctt tagttcgttg
     1381 gcttactccg gataaaggta ttatatctcc agcaatattt attccagtac ttgagaagaa
     1441 tttttttatt gccttagtag ataagtatgt ttttgaggag gtttgtaaat ggattagaaa
     1501 gaggttagat gaaaataaac cttttgttca gatatcagtt aatgtttcaa gaatacaatt
     1561 ttataacact aaatttgtag aaacttattc caatatacaa aataaataca ggatacctaa
     1621 aaatactata gaaattgaat ttacagagag tgttgctttt gagaatcaaa aacatctttt
     1681 ggaaattata catgatttgc atgaaaatgg atttacttgt tctttagatg attttggaaa
     1741 aggttattcg tctttaagtg ttttaaaaga tttaccattt gatgttttaa agcttgattc
     1801 tatgtttttc aaggctagtt tagataaaga taaagagaaa atagtaataa aaaatattgt
     1861 acatatgtta aaagaactta atatcacaac tgttgctgag ggcattgaat gcaaggaaca
     1921 agttgaattt cttagggata ttgggtgtga tttagttcag ggatttgtat tttataaacc
     1981 aatgccaata ttagaatttg aaaaaatatt ggataaagag tttgtttata atagctaaaa
     2041 tgtactttat aaaatatgaa ctaattaagt aaaattattt tgtactgaat aaatttttac
     2101 tttatttaca gaataatgat tatttacaga aaagcgcgaa aagtgtattc ctttaagtgt
     2161 gggatggata gcacaaatag aggagaaaaa atattggcca tataagaatg cataataata
     2221 taaatattta aaaggtcagc attatataaa aattaaaaag aaaataaata atttttctat
     2281 aaaaaagaga ctatgagaaa atttactcat agtctcctaa ataatgtatt tattttcttc
     2341 ctgcaaccca ttttaatccc caatgaaatt cagtatccat ttctctatga cctttgaagt
     2401 atttaactac tttttcaaca ctgaatgtct catcatttac attttctatc aatgctattg
     2461 aacacatatt atagccattt ttatgttcat caagtttgac aactaagtct gaatcttgtt
     2521 tttgtttgat tgttacaatt ccatcagctt cagaccagtt agctacacct tcgtatataa
     2581 aagcataaat aagtattctt tttatatctt ttattttatt accatttatt cttaaatttt
     2641 ctccttgtgt attacttcct gttctgtcat ctccatctaa ttgagcaaaa ggtggattgt
     2701 ctaaactacc aaaggcattt cctaatgctt gaacagcacc ttttacacca tttttcatct
     2761 caaataggca acccaaatct aaatctatat tactgcttct taaagagcca aaaaaaccct
     2821 ttttttgtac tttttgattc caatttaaat taactaaaat ttcacctaaa tcgctatttt
     2881 ccttttttgt aaggtttatt ttttgtccct tttttaattc tatagccata gtaatcttcc
     2941 tccacaaaca tagatttatt taaatggtag cacttaataa gtcaatattc aacaagatta
     3001 gaataataat attaaaatta tactaaatat actaaaaagt aggaatcaca atacctttgt
     3061 atttttcttc aattaagctt cttgctttat ctgatgtaag aacatcttgt agaactttaa
     3121 tcttttcact gtctttatct tcagttctaa atgctaaaag atttgcatac tcgtcattta
     3181 taggagctgt ataaattccg tttttcttgg catcaagacc agcaggtaca gcataagtag
     3241 tatctataaa tgcagcagtc acatctggaa gagaagatgg aatttgagca atatctaact
     3301 ctttgaattg tattcccttt ggattttcta ttatgtcctt aggactaact aatccatccc
     3361 ctttaggtaa cgttaaaagt ccaatacttt caaggtatct aaggttctta gaacaagaag
     3421 atgggttatt gcttattgca attgtatctc cttttttaaa ttcatcaaca gattttatct
     3481 tataagagta aagtattgct gggcatacat atagtttttt accagccatt attttgtaac
     3541 ctttggcctt aacagcttct tttagataag gttcatgttg aaatagattt gcatcaattt
     3601 caccattatt taaagcttcg tttggaagta tgtaatcatc aaagttttta acttctaaag
     3661 tatatccttt ttctttaata agtggtttta attcttctaa taactctcct cctggaacta
     3721 aagtagcacc aacaacaatt tttttatcat ctttagcttt agaacatcca accacagcta
     3781 aagttagtac tagacataat aacaaacata ataatttttt gaatttcata taaattccct
     3841 cctgaatata attgattagt taaaaataaa ataccattct ttatcacact gcaaaataaa
     3901 aataagcctg agtttaaact caggctttaa aagctaattt agactcatct ttcagtataa
     3961 tactgcagga tttagcacca atgtatataa aaatatactg gttgctgggt ttcatagggc
     4021 cagtcccttc accactctgg ataagaagta tcaattttta attatgttat aaatattatc
     4081 atgatttttt acgtctgtaa acataatttt ataaatattt taaaatcttt aatgtatttt
     4141 atttaacacc taaaattcca gaaactagaa tatcagtatc agcacctaag aaatagtcat
     4201 ttatttcaat agaatccaga gtatttctca aagcattttc ttcatgcctt ataccaataa
     4261 gtttattttc tacaaatgca acatcacatt ttccaaaaaa atctccaaaa aattttatac
     4321 tagttattat gcctttatca acatttaaat taaactcaac atttccacca gaatatttta
     4381 attcatttga aagagtatat tttggtgaat taccaaaatt ccaatcccaa gtttcgtatt
     4441 ttgatttagt aagcttttct atttgtttta tatcatgctc actcaaacaa taattagtat
     4501 tatcagtatt tgttttagaa agataatcca ttatagcatc tttaaattct aatatgtcca
     4561 tttttgaatg taaatgttca cttatattgg ttacacgaga ttttacagat tttattcctt
     4621 ttccttcaaa ttttataggt ttaaccttta atgcttttga gaggtcattt atttcagatg
     4681 aaaataaaag agtcccatga tgcattactt tgtttttgta gttgtattga gcatttccag
     4741 aaaatttctt gccatctata agaaggtcat ttcttccaga aaattcggca ttgacatcta
     4801 gtgttttaag taaatctatt atgggctgag tgaatcttct gaaatcacta aaattattat
     4861 tgttacaagc tataaatgta aaatttatat ttcccaaatc atgaaataca gctccaccac
     4921 cagactgtct cctaacgaca ggtatagaat attcttttat atattctaaa tttatttcag
     4981 aaagtgtgtt ttggtttttt ccaacaatta tagaaggttc attcctccat aaaataaata
     5041 agtcttcatc aaaatttttt agaagatatt cttccattgc taaattaaaa taagggtttg
     5101 ttttttcatt ataaattaat aacattaaag tagttcctcc atagaattga taaaattttt
     5161 attatgaata caattaattt tataattcga caataatata aaaactcctt taaattagaa
     5221 attttaaaaa ctaccttgca aagtttaaat aaataatata tactcaaaat atgtttaata
     5281 aaagtgaata gaagggtaga ggcgcaataa tctatcagta ctaataagga gttaagcaca
     5341 gagagttatt aggaaaggag atattgccga agttttataa tcgatgcttt aagattatat
     5401 tgctgggggt acatagaaaa tatgtacaac tgtcacaggt ttatttgtgg tgagctatca
     5461 tttaaggaat tatattatat ttatttttac tattgttgat atattgtaat gtttaagcct
     5521 tgagtgttta ccactcaagg cttttttagt tttattgtaa cataataccc tgtacagttc
     5581 acaaaattaa aaggagaggg agatttatat gaggaacaaa aaaattaata ttatttttct
     5641 gacgacaatc atgttcataa tgtcaacagt aatggttttt gcagaagaag atatagacac
     5701 tattgcacta gccaatgcag aaaaatttgg gattttaact ttaataccac cattagttgc
     5761 tataatactc gcatttataa ctaaaaacgt aataatttct ttacttatag gtattctttc
     5821 tggtagtttt ataattaaag ctagtggtat taatgttttt gcgacattta tacaggcatt
     5881 tttagattta gtagatagag ctttagtatc tttagcagac ccttggaatg cggggataat
     5941 actacaggtt ttgtcaattg gaggagtaat aaatcttgtt gctaaaatgg gaggagctaa
     6001 agctatagct gaagcacttg ctaaaagagc aaagtcagca aaagggacac agcttataac
     6061 atggtttttg gggcttttag tattctttga tgattatgcc aattcactaa tagtaggtcc
     6121 tatgatgaga cctgttgcag ataaaatgaa aatatcgaga gaaaagctag catttataat
     6181 agatgccaca gcagcaccag ttgctggttt agctataata tctacatgga taggtcttga
     6241 ggttggttta atacatgatg cttttgaaag tataagtata gatgtagatg catttggtat
     6301 atttttaaat acaataccat ttagatttta caatatatta atattagctt tcattgtaat
     6361 atcagcatta ttattaaaag aatttggtcc aatgagaaaa gctgagataa aatctagaag
     6421 tagaaaaatt agtatagacc ttgatgaagg cgtagaagag ttggatgatt tagctccaaa
     6481 aaatggagta aaattgagtg tatggaatgc tataatccca ataggaacat tgataatagt
     6541 tgcattagca tcattttatt atagtggata tacatctata atgggaggag acgataaggc
     6601 tctgatacaa ctatttacaa attctccata ttcttttgaa gcaataaaag aagcatttag
     6661 tgcatctgat gcatctagag cattattcca gtctgcactt gttgcaagtt tagttgctat
     6721 tataatggct gtagtaaaaa agatttttac aatatcagaa gcaattgatg tttggataga
     6781 tggaatgaaa agtttagtaa tcactggtgt aatattaata cttgcatggt cattaagttc
     6841 agtaataaaa gagttaggta cagctaaatt tttaatacac ctactatcag gttcactacc
     6901 accattctta ttaccaagtt taatatttgg tttaggagca ataatatctt ttgctactgg
     6961 aacagcttat ggaacaatgg gtatacttat gccacttgca attccattag catactcatt
     7021 aaatcctgat atgtcttatg taatagtaag tactagtgca gttttaacag gtgcaatatt
     7081 tggagaccat tgttctccaa tttcagatac aacaatactt tcttcaatgg gagctggctg
     7141 taatcatata gaccatgtta acactcaaat gccatatgct atatttacag cagtaatcac
     7201 tattgtattt gggtatatac cagctggact tggattgcca atatatatag tattaccagt
     7261 ggcaatagct gctatatttg taggtattca aataattggt aagaaagttg atgaagcgga
     7321 aatagaactt gtagaataaa gatataaata agtttcacct tttattatca ctattttgtt
     7381 agtttttaga taattttaaa aagttattga aaataatggc gaaatatagt aaaataaaag
     7441 agtgataagc ggatgtggcg gaattggcag acgcactaga cttaggatct agcgccattg
     7501 gcgtgggggt tcgactccct tcatccgcac tttacagtac ttaattgtac tgaaaaaaac
     7561 tggggttgct ggctttcgga gtgggctatc ccgtttttat ttttttgtat atataataga
     7621 ttggcacttt agtataaggt gcttttttta taggcaaaaa cagtacattt atttctgttt
     7681 tattatcatt catctattag aatatacttt agttaagaat gtgttaataa gcagtgttca
     7741 cattcttgat aaaatgtgga ataatatgta tttttactaa gacggaaatg aaataattaa
     7801 accattaaat aatattataa gatgatgaat aagtagataa atcaaatttt gtaggaggat
     7861 attatggaaa aatatatatg gttgtttcca ttacttttta tttttcatga tatggaagag
     7921 ataataggtt ttggaatatg gcttaaaaaa aataaatcaa tgcttgataa gaagtatcca
     7981 tttatcagta aagtttatga aaattatagt actgaaggca tggcatttgc tgtgtttgaa
     8041 gaatttattt tatgcattat tttctgtata cttacagtta taacagagaa tcagtatgta
     8101 tatctactat ggttaggtag ttttatagca tataccttac atttggtaat tcatataggg
     8161 cagtcaatca taataagaaa atatatacct tcacttatta ccagtatcat atgcttacca
     8221 ataagcattt ggtgtataag taagagtatt tatatagttg attgtgaaat gagtacaaca
     8281 attctgtaca gtataattgg cattataatt gtagcattga atttaaagtt tgcacagtcg
     8341 ctgattggaa aatttacaaa gtggatgtca aacatataaa ttttagttta ttggacagtt
     8401 caaggaatca gaaattggaa ttttatagta ttaatatttt atggtattaa tataatgtat
     8461 aaaattttat agcaatgtat ttcataagta taaagtgact agaattttaa gaaatataca
     8521 aattctataa aaactaaata atttcaagta tattttaaaa atcttatttt tcacaagttt
     8581 aaaattgtaa acgatttcat caagtctatg aatatacttt taacatgtta tagtaaatct
     8641 caatataaat ttacatttgg ttctttgtgt gttattttaa taataaatta agtgaaaatg
     8701 ttattttaca ttaatatata atatctttgc ataagagtga ataatataaa agagaaataa
     8761 ttgataataa aaacttaaca aaaaaattaa tacataaaaa aaaataaata taatgtgttg
     8821 acatttaatt gaaatattca tacaataaaa ttgaaaataa atatttccaa atgagattag
     8881 cgagagagtc ctttatacga aaaggcgccg aagaagaaat ttaagaaatg ccaattttta
     8941 gagaagcttt caggcaaaaa tatcgctaat tgatgggact ctggagagac ttaagttaag
     9001 atactataag tcaccgaaga agcaaaataa tattaaatta ttaaatcttt caggtataca
     9061 aacagggata tataggctag gattattttc catgctgata tatctttttt ttatgaaaaa
     9121 gtacaggaaa taatatcaaa gttacttaaa tacagtaggt ctaattttct agggagggtt
     9181 atatatgaat gaattgaaaa gagtatcttt gtacaatata cacaaagagc ttggagcaaa
     9241 acttgttgaa tttgctggtt gggaaatgcc tttagaatat gagggtataa ataaagagca
     9301 tgagaaggtc agaaaaagtg caggtatatt tgatgtatct catatgggag aggtacagat
     9361 aaagggagca gagtcagaaa aatttataca aaacctagtt acaaatgata taagcgcatt
     9421 aaagataaat gatattatat atacacctat gtgttatgaa aatggtggag tagttgatga
     9481 tttattaata tataaatttg gtgaagaaga ttatttatta gtaataaatg caggtaatat
     9541 agataaagat gtagcatgga taataaaaca aagtgaagga tacaatgtag atataaaaaa
     9601 tatatctagt gaagtgagtc aattagcaat tcaaggacct aaagcagaag aaattcttca
     9661 aaaaatcaca gatatagact taaactcaat aaaattttat aagtcaattc catcaacaaa
     9721 agtatgtggt tgtccttgtt tagtttcaag aacaggatat actggggaag atgggtttga
     9781 gatatactgt aaaaataaat atgtagaaat aatttggaat gaagttctaa aggttggagg
     9841 agaagatata tgtccagctg gtctaggttg tagggatact ttgagatttg aagcagctct
     9901 acctctatat ggacatgaaa taaatgaaca catatctcca attgaaggtg gtttatctat
     9961 ctttgtgaaa acaaataaag aatcatttat tggcaaatca attttatcaa aagaaaaaga
    10021 aagtggagct aaaagaaagt tagtaggatt tgaaatgcaa ggtaaaggaa tgcctagaaa
    10081 tggatatgat ataaggattg gtgataaaac agttggattt gtaacaacag gatgtgcatc
    10141 tccaacgaca ggaaaaattt taggtatggg aattatagat tctgaatatg caaaagtagg
    10201 aaatgaaata ggtatagcaa tcagaaaaaa agttgttcct gctgtgatag ttaagaaacc
    10261 tttttataaa aaacaatata aaaaagataa tattatatta aacaaagaaa ataaattttc
    10321 atatatacct gctacaagtg aagataaatc aaaaatgtta aaagtagttg gattaaattc
    10381 agttgatgaa ttattttcag atataccaga agaagtaaaa ttaaaaagag atttaaattt
    10441 ggaaattgga aaatctgaat tagaggtaag caaaatagta aaaagattgt cagaagaaaa
    10501 tttaagttta gaagacttga cttgttttct tggtgctggt gcatatgacc attatatacc
    10561 atcaattata aaacatataa cttcaagatc tgaattttat acagcatata ccccatatca
    10621 agctgaaata agtcagggaa ctttacaagt agtttttgaa tttcaatcta tgattgcaga
    10681 aattacaggt atggaaattg caaatgcatc aatgtatgat ggagcaactg ctgcaataga
    10741 agcatgtata atggcaatga atcagactag aaaaagtaaa atagtagtgt caaaaactat
    10801 tcatcctgaa actctgtcag tattaagaac ttacttacaa tataaagatt gtgagatagt
    10861 agaaattgac ttttgtaatg aatatgggac tacagatata gaaaaattaa aagcttctgt
    10921 agacaaagat acagcatgtg ttcttataca aactcctaat ttctttggaa ttattgaaga
    10981 aatggaagaa atagaaaaga taactcatga aaataaggct atgttaatta tgagtgtaga
    11041 cccaatatca ttaggagttt taaaaacacc aggtgagata ggtgcagata ttgttgttgg
    11101 agaagctcaa tcacttggaa accctcttaa ttttggaggt ccttatgtag gatttttagc
    11161 tagcaaatct aaatatacta gaaaaatgcc aggaagaata gttgggcaaa gtttagatgt
    11221 agaaggtaaa attgcatatg tattaacttt acaaactaga gaacagcatg taagaagaga
    11281 aaaagcaact tctaatatat gttcaaatca agctttaaat gctcttgtag cttcaatata
    11341 tatggctact atgggtaaag aaggatttaa agaggttggt atgcagtcta tgaaaaaagc
    11401 acattatacc tacaataaac ttgtacaaac tggaaaatat aagccaatat ttaaaggtaa
    11461 gtttttcaaa gaatttgctg tacaaggaaa tcttaatata gaaactataa atgataaact
    11521 cttagaagaa aatatattag gaggttataa tttagaatac aattatccag aattaaaaaa
    11581 ttcaactttg ctttgtgtga ctgagaaaag aagcaaagag gaaatagata agttagttgg
    11641 aataatggag ggattataat gaaagaatac aatagtttgt tgatagatat atctaaaaaa
    11701 ggtaggaaag catactcact tccaaagtta gatatagatg atataaaaat agaaaatatg
    11761 attgaccaag atatggcaag acaaagtgag ttgaatttgc cagaagttgg tgaattagaa
    11821 ttagttagac attatacatt attatcaaat aaaaactttg gagttgatac aggtttttat
    11881 cctttgggtt cttgtactat gaaatataat cctaaaataa atgaagatat ggcagcactt
    11941 ccaaacttta ctggaatgca tccataccaa tcttcggata cagctcaagg ttctctttct
    12001 ttgatgtatg atttatcaag aagacttgca gaaattacag gtatggatga agttacacta
    12061 caaccttcag caggttctca tggtgagttt acagggctta tgattataaa agcatatcat
    12121 gaaaatagag gtgaccataa gagaaccaaa gtgataattc cagattctgc acatggaaca
    12181 aatccagcaa gtgcagctat ggcaaacttt gatgtgattc aaatagcatc tgataaaaat
    12241 ggagctgtag acataaatgc attaaaagag gttttgaatg atgaagtagc agctcttatg
    12301 cttactaatc caagtactct tggtttattt gaaaaaaata taaaagaaat agctactctt
    12361 gtacatgaag caggaggact tttgtactat gatggtgcaa acatgaacgc tattatgggg
    12421 ataacaagac ctggagatat ggggtttgat gtggttcatc ttaatcttca taagactttt
    12481 tcaactcctc atggaggtgg aggtccagga gctggtcctg ttggagttaa aaaagaatta
    12541 gtaccttttt taccaatacc agtaattgaa agaaaagaag ataagtatgt actaaattat
    12601 gatagagaaa aatctattgg gaaaattaaa aatttctatg gtaattttgg agttcttgta
    12661 agagcttaca catatatact aactatggga agggatggac ttaaagaggc tagtgaaatg
    12721 gcagttttaa atgctaatta tataaaggaa agtataaaag atgattatat tttgccaata
    12781 gataccttgt gtaagcatga gtttgtatta ggtggattgc caagaggaga ggccaatata
    12841 aaaactatcg atattgcaaa aagactacta gattatggat accatcctcc aacaatgtac
    12901 tttcctctta ttataaatga ggcacttatg atagaaccta cagaaagtga gagtatagag
    12961 acattagata gttttataga agctatgaaa agtgttgcta aagaggcaaa ggaagaacca
    13021 gaactattga aaactgctcc acataatact ttggtcaaaa gagtagatga tgcaagggca
    13081 gtaaagaaac ctatactaac atggtcacaa agataaatag ttaaaaagta gagatttaaa
    13141 gtataaagag aattaaattt gtaagaaaaa gctatctaac ttaatctagt ttagatagct
    13201 tttttgtata ttagtatgta tggtattttc tatataaagt tttaaattat attagtgctt
    13261 atatagaata ttgatatgat gattatgtat agatattaat aagaattgtt gaatttatct
    13321 tgccttaact ttatttactc ttttatatta agaaaaactt aactaaaata tagcgaaatt
    13381 cataaaaatt taggaaatct taagaattat aatatttaaa tctttagatt tatattttat
    13441 tatataaact atagaataat aaaataaaaa aattgagaat tttataatat atttgtagat
    13501 ttgagtataa aaaagtgcta agttgaaagg agtaaaatat ggataaggtt aatttagaaa
    13561 ggtatagttg tgatataaat gttggtttaa ataaaaatca acttcaaagt agaatagatg
    13621 ataatttaat taatgcattt gataatggaa aaaccaaaac atataaacaa atttttaaag
    13681 acaatatatt tacacttttt aatctcataa atattgtttt agtctgttta ttagtttcag
    13741 ttggttcttt taaaaatacc ttatttatat ttattgctgt aattaatact attataggag
    13801 taatacaaga gataagagct aaaagattat tggacaatct atctgttata gtttcaaata
    13861 aggtatctgt cataagagaa aaagagaaaa aagagattga tgtacaagaa ttagtattag
    13921 atgatattat gattttaaaa acaggtaatc aaatttgtgc agattcaaaa gttttaaatg
    13981 gaaaattaga ggtaaatgag tctttggtta caggtgaatc tgatattatt ataaaaaata
    14041 aaggcgattt tttatattct ggaagttttg tagtttctgg agaagctttt gtaagagttg
    14101 aaaatatagg aaaagataac tatgcaaata agatagctaa tgatgcaaag atttctaaaa
    14161 aacataattc tcaacttaga aattcattaa atgcaatatt aaaaattgta ggtataataa
    14221 taattccttt aggaattata ttgtttgcaa aacaacattt tggaaatgga gattctatag
    14281 ctacatctgt agtaggtaca gtggcagctg taaatggtat gataccagag ggattaacat
    14341 tacttacgag cattgctcta gctgtaggaa ctataaaact tgctagtcat aaaactttag
    14401 tgcaagaact gtactgtgta gagactcttg ctagagttga tacactatgt cttgataaga
    14461 caggtacaat tacagaaggt aaaatgcaag ttgatgatat agtaatgttg gaagaagtgg
    14521 atattaatga aataatgggg aatatatgta attctctcaa agatgataat gcaacactaa
    14581 atgcaataag agataagtat aatgttttag atacgtataa agctaagaat ttaataccat
    14641 tttcttcaga aagaaaatac agtggggtta cctttgaaaa taaaggtaca tatttattag
    14701 gtgcatttga atttatattt aaggaaaaaa ataaaaaact taggatagaa gttgaaagat
    14761 attctaaaaa aggaaacaga gtaatagttt tagctcatag tgattcttat atggaagata
    14821 ataatattcc tgaagatata aagccactag cttttatatt gatattggat aaaattagag
    14881 atgaagctaa ggaaacttta gaattttttt acaatgaagg tgtagatata aaaattatat
    14941 ctggtgacaa tcctataaca gtaagtgagg tagctagaaa agcaggtctt aaaacagcta
    15001 gtaattttat tgatgcaaca acacttaaaa atgatagtga tatatacaaa gcagttgata
    15061 aatacagtgt ttttggaagg gtaagcccac aacagaaaaa acaaatgatt ttagcattaa
    15121 aaaaacaaaa tcatacagta gctatgactg gagatggtgt aaatgatgtg ctagcactta
    15181 aagaagcgga ttgtagcatt gccatggcat ctggaagtga tgttactaag aatgtgtcta
    15241 atttagtctt attagattca aactttgcat caatgccaaa ggttgttatg gagggaagaa
    15301 aagtaattaa taacattcaa agagcatctt ctttgttttt agtaaagaca attttttcat
    15361 tcttcttgtc gttattaaca ttattcttct tcagtagaca gtatccattt gttcctatac
    15421 aattatcact cattggggct gtaacagtgg gtataccatc attcttctta gctcttgaag
    15481 caaacaaaag tagaatttca ggaaattttt tactcaatat attaaaaaat gctttaccag
    15541 gagcactatg tgtgacagta aatgtaatta ttgtttacaa tatagttgaa tatttaggtt
    15601 atagttcaag tgtattttcc acaatgtgtg ctatattaac tggtgtatgt ggtcttttaa
    15661 tattaagaca acaatgtttg ccatttaata aagaaagatt atttttaata gtaagtatga
    15721 ctattgcatt tgttattggg attctatttt taggtggatt attctcattt gtagcattga
    15781 gtagagaatt aattctcata actatggcat tagcaatatt aatgccaatt atgataaaag
    15841 ttatgttatt tgtcttagat gagatattag agacaattgt tccagattta aattaatttt
    15901 aaaatgatat aaataagagc agttttagtt gaactgctct ttttagatgt gtttaatttt
    15961 atgtaagaat atgtattttt attaatcagc tatatatgag caacagtagt caacaacttc
    16021 attaaccttt aagtcaaaac ttgaatcact aggaacatta aatttttgcc cttctttata
    16081 agttacaaac tcattgcttc caggcagttt tacatccata cttccagcaa gcatctccat
    16141 tatttcttct tctctagtag aaaaagtgta ttctcctggc aacattaatc ctaaagtttt
    16201 tctttctcca ttaggcagta ttattactct gctacttacc ttaccatcaa aataaacgtt
    16261 tgccttcttt actgcagtaa cattcttaaa ttcactcatt agataaaacc tccaaaatta
    16321 tttgtacata tatattatat aaaaataatg taaaaaatgc tatatattta caaaaaaatt
    16381 tagtatttat taaaaaaatt aataagaata aaaaagagat gaaattgctt aaattgataa
    16441 aaaatataaa ataaattgca aagtaagcaa gaaaaga
//
LOCUS       DAMJWC010000081        15978 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMJWC010000081 DAMJWC010000000
VERSION     DAMJWC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.083"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="PC503_003095"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="PC503_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF2529056.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="PC503_003096"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="PC503_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF2529057.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="PC503_003097"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="PC503_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF2529058.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGSGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="PC503_003098"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="PC503_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF2529059.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="PC503_003099"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="PC503_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF2529060.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /locus_tag="PC503_003100"
     CDS             2662..3168
                     /locus_tag="PC503_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF2529061.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="PC503_003101"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="PC503_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF2529062.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3982..4770
                     /locus_tag="PC503_003102"
     CDS             3982..4770
                     /locus_tag="PC503_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2529063.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5241..8957
                     /gene="rpoB"
                     /locus_tag="PC503_003103"
     CDS             5241..8957
                     /gene="rpoB"
                     /locus_tag="PC503_003103"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF2529064.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            8999..12484
                     /gene="rpoC"
                     /locus_tag="PC503_003104"
     CDS             8999..12484
                     /gene="rpoC"
                     /locus_tag="PC503_003104"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF2529065.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12773..13195
                     /gene="rpsL"
                     /locus_tag="PC503_003105"
     CDS             12773..13195
                     /gene="rpsL"
                     /locus_tag="PC503_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF2529066.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13319..13789
                     /gene="rpsG"
                     /locus_tag="PC503_003106"
     CDS             13319..13789
                     /gene="rpsG"
                     /locus_tag="PC503_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF2529067.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13838..15904
                     /gene="fusA"
                     /locus_tag="PC503_003107"
     CDS             13838..15904
                     /gene="fusA"
                     /locus_tag="PC503_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2529068.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6257 a         1988 c         3249 g         4484 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggatc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgaaag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctgtata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgtttataa ataaaatgta ataaataatt aattaacaaa
     3901 tataaatttt aaaataagtt agatatttag aaaaatcgaa atttgtagga tttaaaggac
     3961 atattcaagg aggagttaat aatggaaaaa ttacaaggaa aaattgcagt agttactgca
     4021 gcaacaaaag gtattggatt agcatcagca gagatattag caaaaaatgg agcaactgtg
     4081 tacttagcag ctcgttcaga agaattagct aatgaagtta taaataaaat aagtgcagaa
     4141 ggtggttgtg ctaagtttgt ttactttaat gctcgtgaag aagagacctt tacctcaatg
     4201 atagaagagg tagttaaaaa agaaggtaag atagatatac ttgtaaacaa ttttggttca
     4261 acaaaccctt ctcttgacaa agaccttgta actggggata cagataattt ctttgacaca
     4321 gtaaatacta atttaaaaag tgtgtattta ccatgtaaag cagcaattcc tcatatgata
     4381 aagaatggaa aaggaagtat agtaaatata tcaagtatag gttcagtatt acctgattta
     4441 tctagaatag cttactgtgt atcaaaagca gcaatcaact cattaactca aaacatagct
     4501 acacaatatg ctaaagacaa tgttagatgt aatgctgtac ttccagggct tattgcaact
     4561 aaagcagcat tagacaatat gtctccagag ttcataaaag aatttttaaa gcatgttcct
     4621 ttaaatcgta taggggaacc agatgatata gcaaaagctg ttctattcta tgctagtgat
     4681 gactcatcat ttataacagg ggatttactt gaagttgcag gaggatttgg tttacctact
     4741 ccacaatttg cagataatat attaggataa ttaaattact aatatgcaat gaaagcttat
     4801 gcattagtta tagtagaaat gatattttta taaaggccat agatataatt tatattggaa
     4861 aggtttgagg ttcaaaattc caagttaaat ttatttatgg tctttatttt gtatatttta
     4921 ataaattgta tatatttgta taaatgtaat tatttacaat cattttaata tggaattata
     4981 attaaatagg ggggatggta cttgtataaa attttttata gaaaattaga cctataaatg
     5041 aaaaatatgg attttatatt ggaaaattgt acataataca taatatatgc ttaaaataat
     5101 ttacaaaaaa tcaaaaataa tgcatagttt acatataaga taaaaaatat attgaaaaat
     5161 acttgacatt atgctaaaat tattagatgc gttagaatga actattgttt tatttttaat
     5221 tattgagagg tgaaaagtga atgccacatc ctgtcacgat aggtaaaaga actagaatga
     5281 gcttttctaa aattaaggaa atagctgatg tgccaaatct tatagaaatt caagtagatt
     5341 cctatgagtg gtttttaaaa gaaggtttaa aagaagtgtt tgatgatatt tcaccaatag
     5401 aagattatac tggtaatctt atattggaat ttgtcgacta ttctctagat gataaaccaa
     5461 agtacgatat agaagagtgt aaagagagag atgctacata ttgtgcacct ctaaaggtta
     5521 aggtaagact tataaataaa gaaacaggtg agataaaaga acaagaagtg tttatgggtg
     5581 acttcccttt aatgacagaa agaggaactt tcgttataaa tggagcagaa agagttatag
     5641 taagtcaatt agttagatct cctggtgttt actatgcgga agaaagagat aaaacaggta
     5701 agagattgat ttcatctact gtaattccta atagaggagc atggttagaa tatgaaacag
     5761 attctaatga tgtaatatct gtaagagttg atagaacaag aaaacaacca gttacagttt
     5821 tacttagagc tttaggaata ggaacagatg cagagataat tgacctttta ggagaagatg
     5881 agagattatc tgctacatta gaaaaagata atactaagac agtagaagaa ggtcttgtag
     5941 agatatacaa aaaattaaga ccaggtgaac ctcctactgt agaaagtgca tcatctttat
     6001 taaatgcttt attctttgac ccaaaaagat atgacctagc aaaagttggt agatataaat
     6061 tcaataagaa acttgcttta tgttatagaa taatgaataa aatttcagca gaagacataa
     6121 taaatccaga aactggagaa gtatttgtaa aagctggaga aaaaataagc tatgatttgg
     6181 ctaaagccat acaaaatgca ggtataaatg tagtaaatct actaatggat gatgataaaa
     6241 aagttagagt tataggaaat aattttgtgg atattaagtc tcacattgat tttgacatag
     6301 atgatttaaa cataaaagaa aaagtacatt atccaacttt aaaagaaatt ttagatggat
     6361 atagtgatga agaagaaata aaagaggcta taaaatcaag aattaaagaa cttataccaa
     6421 aacatatatt attagatgat ataatagctt caataagtta tgagttcaat atattctata
     6481 atataggaaa tattgatgat atagatcacc taggaaacag aagaataaga tctgtaggtg
     6541 aattgttaca aaatcaagtt agaattggtc tttcaagaat ggaaagagtt ataaaagaaa
     6601 gaatgacggt tcaagatatg gaagctataa cgcctcaagc gttagttaac ataagaccag
     6661 tttcagctgc aataaaagaa ttttttggta gttctcagtt atctcagttc atggatcaaa
     6721 caaatcctct atctgagtta acgcataaga gaagattatc agcccttggg cctggaggtc
     6781 tttcaagaga aagagctgga ttcgaagtgc gtgacgttca ccattcacac tatggtagaa
     6841 tgtgtccaat agagactcca gagggaccaa atatcggtct tataaactct ctaggaactt
     6901 atgcaaaaat aaatgaattt ggatttatag aatcaccata tagaaaattt gataaagaaa
     6961 catcaacagt tactgatgaa atacattatt taactgctga cgaagaagat ttattcgtaa
     7021 gagctcaggc aaatgagcca ttaacagaag atggtaaatt cgtaaaccat agagttgttt
     7081 gtagaactgt aaatggtgct gttgaaatgg ttcctgaaag tagagtagat tacatggata
     7141 tatctcctaa gcaggttgta tctgttgcca ctgctatgat acctttctta gaaaatgatg
     7201 atgccaaccg tgcccttatg ggagcgaaca tgcagcgtca ggcagtgcct ctagttagaa
     7261 gagaagcacc aattatagga actggtatag aatacagagc agcaaaagac tctggagcag
     7321 ttgttgttgc tagaaattct ggtatagcag aaagagtaac agcagatgaa ataattataa
     7381 aaagagaaga tggaaacaga gatagatata atctacttaa gtttaaacgt tcaaactcag
     7441 gtacttgtat aaatcaaaca cctataataa ataagggtga ccagataata aaaggtgatg
     7501 ttatagcaga tggtccagca actgatttag gagaagttgc acttggaaga aactgtctta
     7561 tagcattcat gacttgggaa ggttataact acgaggatgc tatattaata aatgaaagat
     7621 tagttaaaga agatagatta tcaacaattc atatagaaga atatgaatgt gaagctagag
     7681 atacaaaact agggccagag gaaataacta gagatatacc taatgttgga gatagtgcaa
     7741 ttaagaactt agatgacaga ggtataataa gaataggtgc agaagtagac tcaggtgata
     7801 tattagttgg taaagtaact ccaaaaggag aaactgaact tactgctgag gaaagattac
     7861 ttcgtgcaat atttggagaa aaggctagag aagttagaga tacttcactt aaagtgcctc
     7921 atggtgaatc tggtataata gttgatgtaa aagtatttac tagagaaaat ggagatgatt
     7981 tatctccagg agtaaatgaa ttagtaagat gctatatagc taaaaagaga aaaataaaag
     8041 ttggagataa aatggctggt cgtcatggta ataaaggggt tatctcaaga gtattacctg
     8101 aagaagatat gccattcatg gaaaatggaa caccactaga cataatactt aacccacaag
     8161 gtataccatc acgtatgaac attggtcagg ttttagaagt tcatttagga cttgctgcta
     8221 agacattagg atggtatgta gcaacatcag tattcgatgg tgctaatgag tatgacataa
     8281 tggatgctct tgaagaagct gggtatccta gagatggtaa attaacttta tatgatggta
     8341 gaacaggtga gtcttttgac aacagaataa ctgttggata tatgtactac ttgaaactac
     8401 atcacttagt agatgaaaaa ctacatgcaa gaagtactgg accatactca ttagttactc
     8461 aacagccact aggtggtaaa gcacaatttg gtggacaaag atttggagag atggaggttt
     8521 gggctctgga agcatatgga gctgctcaca tacttcaaga aatacttact gttaagtctg
     8581 atgacgttgt aggtcgtgtt agaacatatg aagctatagt taaaggtgaa aatatacctg
     8641 aaccaggaat cccagaatca tttaaggttc ttataaaaga acttcaaagt ttatgcttag
     8701 atgtaaaagt attgacagat gaagaccaag aaatagaagt aagagaatct gtggatgaag
     8761 atgatacaat aggtgaattt gagctagatg ttgtaaatca tatgggagaa gttgaagaaa
     8821 gtaatataat agaagaaatt gaagatgatt ttgcagaaaa tgcagaagat gaggatatag
     8881 agaatttaga agaattcact gaagatgatt tatttgaaga agaaatagat tttgatagtg
     8941 atgactttga tatgtaaatt taattaatgt aaatctcaaa tagaagggag agaactcctt
     9001 gtttgaatta aacaatttcg agtcgataaa aatagcattg gcttctccag aaaaaataag
     9061 acaatggtct aggggagaag ttaaaaagcc agaaactata aattaccgta ctttaaaacc
     9121 agaaaaagat ggtcttttct gtgaaagaat atttggacca caaaaagact gggagtgcca
     9181 ctgtggtaaa tatagaagag ttagatataa aggtgtagtt tgtgatagat gtggagtaga
     9241 agtaactaaa tcaaaagtaa gaagagagag aatgggacat atagagctag ctgctcctat
     9301 gtctcacatc tggtacttca aaggtatacc aagtagaatg ggacttttac ttgatatgtc
     9361 accaagatcg ttagaaaaaa tattatactt tgcctcatat gtggtagttg atccaggaga
     9421 gactggatta aacgaaaaac aattgcttac agaaaaagaa tacagaactg ctcttgaaaa
     9481 gtatggatat acttttactg taggaatggg tgctgaagct gtaaaaacat tactacaaaa
     9541 tatagattta gagcaacaaa gtaaagacct aagagcggag ttaaaagata gtacagggca
     9601 aaagaaagtt agaacaataa gaagattaga agttgtagag gcatttaaaa agtctggaaa
     9661 taaaccagaa tggatgattt tagatgcaat accagtaata ccaccagatt taagaccaat
     9721 ggtacaactt gatggtggaa gatttgcgac ttcagaccta aatgatttat atagaagagt
     9781 tataaataga aacaacagac ttaaaagatt attagagctt ggagctccag atataattgt
     9841 aagaaatgaa aaaagaatgc ttcaagaagc tgttgatgca ttgatagata atggtagaag
     9901 aggtagacct gtaacaggac ctggaaatag accacttaaa tctttatcag atatgttaaa
     9961 aggtaagcaa ggtcgtttcc gtcaaaactt acttggtaag cgtgttgact actcaggacg
    10021 ttctgttata gttgttggac cagaacttaa attttatcaa tgtggacttc caaagaagat
    10081 ggcattagaa ttattcaagc catttgttat ggataaatta gttaaagaag gttatgcaca
    10141 taatataaaa agtgcgaaat ctatagtaga aaaagttaag ccagaagttt gggatgtttt
    10201 agaagatgtt ataaaaagtc atccagttct tcttaaccgt gcaccgactc tacatagatt
    10261 aggtatacaa gcatttgaac caatcttagt tgaaggtaag gctataaaac tacatcctct
    10321 tgtatgtaca gcttataatg cagactttga tggtgaccaa atggcagttc atgtaccttt
    10381 atcagtagaa gcacaagcag aagcaagatt cttaatgctt tctgtaaata atatacttgc
    10441 tcctaaagat ggttcaccta taactactcc atctcaggat atggttttag gttgctatta
    10501 tctaacaata gaagcccaag atggagctaa aggaacaggt atggtattta aagactttaa
    10561 tgaactatta cttgcttatt acaataaatc agttcatcta catgcattag tgaaacttaa
    10621 ggtaacactt gaagatggaa gaagttcatt ggttgaaagt actgttggta gatttatatt
    10681 taatgaaaat atacctcaag acttaggttt tgtagataga aaagaaaatc catttgcact
    10741 tgaagttgat ttcttagcag ataaaaaatc tcttggtaaa ataatagata aatgctttag
    10801 aaaacacgga aatacagaaa cagctgaatt actagattat ataaaagctc taggatttaa
    10861 atattctaca ttaggtggca taacagttgc tgttgatgat atgagtgtcc cagaagaaaa
    10921 gaaagtattt atagctgagg cagaagctaa agttgataag tatgaaaaag catacagaag
    10981 aggtctaatc tctgatgaag aaagatatga aaaagttata gagacatgga cagaaacaac
    11041 tgataaagtt actgatgctc ttatgggtgg actagataga ttaaataata tatatataat
    11101 ggcacattca ggagccagag gttctaaaaa ccaaattaga cagctggcag gtatgcgtgg
    11161 tcttatggca aatgcatctg gtaaaacagt tgagatacca gttaaatcta atttccgtga
    11221 aggtttatca gtactagaat actttacatc ttcacatggt gccagaaaag gtcttgccga
    11281 tacagctata cgtacagctg aatctggata tttaacaaga agacttgttg atgtaagtca
    11341 agatgttatt gtaagggaaa tagattgtgg aacagaagat actacagaga tttatgctat
    11401 aaaagaagga aatgaagtta tagaagagat atatgataga attgtaggaa gatatactat
    11461 agaccctata ttaaatcctg aaactggaga agttatagtt gaggctgatt caatgataca
    11521 agaagatgaa gcagaaacta tagtagcttt aggaattgaa aaaattagga taagaacagt
    11581 tcttaactgt aaaactaatc atggagtttg ttctaagtgt tatggtagaa acttggcaac
    11641 aggaaaagaa gttaatatag gtgaagcagt tggtataata gcagctcaat ctatcggtga
    11701 gccgggtact cagcttacaa tgcgtacatt ccatactgga ggagttgcag gagctgatat
    11761 aactcaaggt ctaccaaggg ttgaagaatt atttgaagct agaaaaccaa aaggattagc
    11821 tgtaataact gaagtatctg gtagagttga aattgatgaa acaggaaaga gaaaagaagt
    11881 aaatgtaata ccagaagaag gcgagactca aacatatgta attccatatg gttctagatt
    11941 aaaagttaag caaggtcaaa tgctagaggc tggagaccct ctaacacaag gatttataaa
    12001 tcctcatgat atagtaagag taaatggtgt taagggagtt caagaatata tagttaaaga
    12061 agttcaaaga gtgtatagac ttcaaggggt tgatgttaat gataagcata tagaagttat
    12121 agtaagacaa atgctatcta aagtaaaagt tgaagaccca ggagatacag atttattgcc
    12181 aggtggatat gaagatgtat taacattcaa tgaatgtaat aaagatgcta tagataaagg
    12241 tctaagacca gcagttgcta aaagagtttt acttggtata actaaagcat ctcttgcaac
    12301 tgattcattc ttatcagcag cttctttcca agaaacaaca agagtattaa cagaggcagc
    12361 aataaaaggt aaagaagacc acttaatagg acttaaagaa aatgttatat taggtaagtt
    12421 aataccagca ggaacaggaa tgaagaaata tagaaatata gctgttgaaa aaattgaaga
    12481 ttaatagcat atagagtaaa gaaatcttga caaccattat ttgtggtgtt aaaatagtaa
    12541 agtgtgttgt ttaaaagtac actaagggct tgaacaagtt cttagtgact tttagatggc
    12601 aataaatgag aactaaaaag catcaagcta gaaaagtgct aatatcacat atttatgtgt
    12661 tatagacatt aaattgtaag taacgaatgt tacaatcagt cagtatgaat attcatattg
    12721 atgtagttgg cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac
    12781 aattaaccaa ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc
    12841 attacaaaaa ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa
    12901 aagaggggtt tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag
    12961 aaaagttgcc agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga
    13021 aggacacaac ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct
    13081 tccaggggtt agataccata tactaagagg tactctagat acagcaggtg ttgataagag
    13141 aagacaatca agatctaaat acggtgcgaa gagacctaaa gaagctaaaa agtaaaaaca
    13201 attaatgatt gattatagtt cggtgcttta aatatatata tatttacggc atcacggcat
    13261 taaatgattt atgtcgagta cctatgattt aagttaaata attaaggagg gaagcgaaat
    13321 gccaagaaaa ggtaatattc caaaaagaga agttttacca gatcctatgt atgggagtaa
    13381 ggtagttact aaattaataa ataatctaat ggtagacgga aaaaaaggaa agtctcaaag
    13441 aatagtttat gatgctttcg caattgttgc tgaaaagaca ggagaagaag ctttagaagt
    13501 atttaataaa gcaatggata atataatgcc tgttttagaa gtaaaagcaa gaagagttgg
    13561 tggggcaaac taccaagtgc caatcgaagt tagacctgaa agaagacaaa cattaggttt
    13621 aagatggcta gtaaaatata ctagagctcg tggagaaaaa ggaatggttg aaaagctagc
    13681 taaagagata atggacgcag ctaacaacac tggagcttca gttaagaaaa aagaagatac
    13741 tcataaaatg gcagaagcta ataaagcatt tgctcattac agatggtagg atatatagat
    13801 atcttataaa attgaggata tcataaggag gataaccatg gctagaaagt ttcctttgga
    13861 aagaactagg aatataggaa tcatggctca tatagatgca ggaaaaacta ctactacaga
    13921 aagaatcctg ttttatactg ggcaaactca taaaatagga gaaactcatg aaggagcttc
    13981 tcaaatggac tggatggagc aagaaaagga aagaggtata acaataactt ctgccgctac
    14041 tactgcttca tggaaagacc atagaataaa cataatagat actcctggac acgtggactt
    14101 cacagttgag gttgaaagat ctctaagagt tcttgacggt tcagttgctg tattctgtgc
    14161 aaaaggtggg gttgagcctc aatcagaaaa tgtatggaga caagctgaaa cttatggagt
    14221 acctagaata gcttttgtaa ataaaatgga tatattaggt gcagatttct acaatgttgt
    14281 aagcatgatg aaatctagat taaattctaa tgcagttcct atgcaattac caataggtaa
    14341 agaagattca tttataggta taatagactt attaaaaatg gatgctgtta tatacaaaga
    14401 cgacctaggg gttgaaatgg aagaaacaga tataccagaa gatatgaaag aattagctgc
    14461 tgagtggaga gaaaaattag ttgaatcagt agctgaaact gatgaagaat taatgatgaa
    14521 ataccttgaa ggtgaagaac ttactataga tgaattaaaa gttgctataa gaaaagctac
    14581 tatagcttgt gaaatgaacc cagttttctg tggtacagct tatagaaaca aaggtgttca
    14641 gttagtaata gatgcagttt tagattactt accagcgcca actgatatac cagctataaa
    14701 aggtatatta gcagatggag aagaagctga aagacattct tctgatgaag agccattctc
    14761 tgcattagca ttcaaaataa tgactgaccc attcgttgga aaactagcgt tcttcagagt
    14821 ttattctgga acattagaat caggttctta tgttttaaat gcaactaaga ataagagaga
    14881 aagaattggt cgtatattac aaatgcatgc taatacaaga gaagaaataa ctaaagtgta
    14941 tgctggagat atagcagcag cagtaggatt aaaagatact actactggag acacattatg
    15001 tgaccctgct aatccaataa tacttgaatc tatggaattc cctgagccag ttatatctgt
    15061 tgctatagaa ccaagttcta aagcagctca agaaaaaatg ggtatagctc ttcaaaaatt
    15121 agctgaagaa gacccaactt tcacagttaa gactgaccaa gaaacaggac aaactataat
    15181 atctggtatg ggtgaattac acttagagat aatagtagat agattattaa gagaatttaa
    15241 agtagaagct aaagttggtg caccacaagt tgcatataga gagactataa ctcaaccagt
    15301 tgatgttgaa tacaagtact ctaagcaatc aggtggtaga ggacaatacg gtcacgttaa
    15361 gattagagtt gctcctcaag agccaggtga aggatacaaa ttcacaaaca aaactgttgg
    15421 tggatcagta ccaaaagaat atgttggtcc agttgacatg ggtatacaag gagctatgca
    15481 atctggtata gttgctggat atccagttgt agacgttgct gttgagttat atgatggttc
    15541 ttaccatgag gttgactctt ctgagatggc gtttaagatg gctggttcaa tggcattcaa
    15601 agatgctatg aagaaaggta atgcagttct tttagagcct tacttcaaag tagaagttgt
    15661 tactccagaa gattacatgg gagatgttat gggtgactta aactcaagaa gaggattaat
    15721 ccaaggtatg gaagctagaa gtggtgcaca agttataaat gcattcgttc cactttcaga
    15781 aatgtttgga tactcaacag acctaagatc ttcaactcaa ggtcgtgcaa cttacacaat
    15841 gatattcgat cactatgagc aagttccagc ttcagttgct aagaaaatag ctgaaggaaa
    15901 ataatttaaa aataattaat aatataaata taaaaaataa tcagctagat gagagatatc
    15961 tctcatctag cacaagat
//
LOCUS       DAMJWC010000082        15881 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMJWC010000082 DAMJWC010000000
VERSION     DAMJWC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.084"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            471..2705
                     /locus_tag="PC503_003108"
     CDS             471..2705
                     /locus_tag="PC503_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2529069.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2736..3581
                     /locus_tag="PC503_003109"
     CDS             2736..3581
                     /locus_tag="PC503_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2529070.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3821..5554
                     /locus_tag="PC503_003110"
     CDS             3821..5554
                     /locus_tag="PC503_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2529071.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5886..6366
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5952..5974
                     /rpt_unit_seq="ataccacttagttaatataaaac"
     gene            complement(6896..7000)
                     /locus_tag="PC503_003111"
     CDS             complement(6896..7000)
                     /locus_tag="PC503_003111"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2529072.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7625..7870
                     /locus_tag="PC503_003112"
     CDS             7625..7870
                     /locus_tag="PC503_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529073.1"
                     /translation="MNQKKIKISIKMVIIGIFSVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8623..8769)
                     /locus_tag="PC503_003113"
     CDS             complement(8623..8769)
                     /locus_tag="PC503_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529074.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            8802..9188
                     /locus_tag="PC503_003114"
     CDS             8802..9188
                     /locus_tag="PC503_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529075.1"
                     /translation="MNNNKFVAPNNVTLVERCYRYIKDRECSFSPNTIRNRKNMIKNQ
                     IEVFFKDMKLIDITPSILQSYINNIYNEHMLNSIKNQVDFIKSVLKESYRLKEISENI
                     CDFVTTPIKKVVQLLSFIQNKKLNYY"
     gene            10055..11410
                     /locus_tag="PC503_003115"
     CDS             10055..11410
                     /locus_tag="PC503_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2529076.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11528..12196)
                     /locus_tag="PC503_003116"
     CDS             complement(11528..12196)
                     /locus_tag="PC503_003116"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF2529077.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREELVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12263..12691)
                     /locus_tag="PC503_003117"
     CDS             complement(12263..12691)
                     /locus_tag="PC503_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2529078.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12798..13391
                     /locus_tag="PC503_003118"
     CDS             12798..13391
                     /locus_tag="PC503_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF2529079.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13510..14445
                     /locus_tag="PC503_003119"
     CDS             13510..14445
                     /locus_tag="PC503_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF2529080.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV"
     gene            complement(14716..15660)
                     /locus_tag="PC503_003120"
     CDS             complement(14716..15660)
                     /locus_tag="PC503_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2529081.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
BASE COUNT         6051 a         2078 c         1984 g         5768 t
ORIGIN      
        1 atttattata gtctttaaca aaaaatacaa gaataaactt aattttaata actaaaatta
       61 attatgcaaa attattaata tggtattaaa ttatgtataa aaagttaatt atgaataaaa
      121 taattatgcc tttgaaaaat cattaaactt aaaattaatt ataaaaaaac tctaccttac
      181 taactataca gctcacaatc tatctattta tgaaaaaata tgatataatt gcattcaaaa
      241 aggaaatctt tcaatatact agaatttaag cattaactaa ttttatctaa tattattact
      301 aaactaaaaa atatttgtat ttgtagcatt ggagcaaata acttaatgta tattcatttt
      361 aaatacttat ttaaaattta gcatttaaat tatttacaaa ttaacattta aatacttcta
      421 gcataaatac agttgtcatc aaaatttaaa gtatcttatg gaggaatacc atgcaaaatc
      481 ataattatat aaaaatgtta aataaaaagg tagaagtatt atctaaggaa ttagatagta
      541 gaaattttaa attaaaaacc ttaaatgaaa tagatttttt ttctaaaata ccaaacagag
      601 aatttatgta ccaacatatt gatgactgta tttcgaaaaa tatacatata ggaatcatgt
      661 tattaaatat cgataacttt aaattattta atgatatata tggataccta gtcggagaaa
      721 atttattaat tactctaact caaaacctat tgcactttat tccagaatca aagggaatag
      781 tcgcttattt aaaaggagaa ggttttttaa ttgtacttcc aaatgtatca aataaagagt
      841 taaataatat gggtgcaact attatagaga gcgcccgaga attaaaaata agacttccta
      901 atgaaaaaga aatatactcc aatgttacat ttagtatcgg cagcactatc tggaatggtg
      961 aaccaaacat gactactttg atgcttttca accaagtgta tagtgcttta aaaaaggcta
     1021 aaagtgaagg taaaaataga tacattctat ttgattttaa agataatagt ttttacaata
     1081 aattagaaaa tgataaggag ttcttatcag aaatatcaca tgttctacaa actaaacaaa
     1141 ttgaagtatt ttaccaacca ctttataata taaaaaataa tactatagtt ggatgtgagg
     1201 cacttgcaag atggagacac cctattaaag gacttcttac tccagataaa tttattcctt
     1261 tatttgaaca gtttggtctg ataacggaat tagatttgca tttatttgaa gagaactgta
     1321 aaaatataag aagatggatt gataacaatg atgtttttgt tccaatttgt tgtaactttt
     1381 ctcgtcttca tttttttaac cctaattttc caagtatgct aaaaggtatt actgaaaagt
     1441 acagcgtctc tacatcaaat tttagcattg aaataacaga aaatatatta atagaaaata
     1501 caaatacaat tattcaacaa ctagctgaac ttcgttctta tggtttttct gtatcaatgg
     1561 acgattttgg ttctggatat tcatcttttg gtatgttgca aaatctacct tttgatataa
     1621 tcaaaattga taggatattt ttatctcata atttaaatga ttttaaaaat acaaccattt
     1681 tgtactctat aataaacatt gcaagagctc ttgggatgct tacagtatgt gaaggtgttg
     1741 aaacagaaca acatgtagaa tttattaaaa gtataaattg tgatatcgcc caaggttatt
     1801 attatgcaaa acccatggag tgcaaagaat ttgaaaaatt actatctaaa gagaataatt
     1861 cagagaaaat gtttataaaa tattctgata taggaaaatc tttaatagag aagatatttg
     1921 atggattttt tattatgcaa gatatgaaaa aactaagagc taatgtcact gaagacattc
     1981 aatggtttga tttttacaac aaaactgaaa ttacatcttt tcctaaagta atagagcatt
     2041 ttgaaaaaca tattaaaggt aaaaaatttt ctattcttta caaaagtata accccacata
     2101 atactgaatc agattcatta ttaattagtg gagaagccgt tttatcagat gaagcttctg
     2161 aacatcaaaa atatagcaat ttctacttta gtgcaaattg tataatttca gaaaataaat
     2221 tactcttagc aaaattacat ttggatttaa ttaaaactgc tggctatata aatgaatttg
     2281 aatcatattc aatacctaaa atgacaaata cacatcttga tgaaagtaat attttatcac
     2341 aattttattc aatgttgcct gtaggtataa ttcgctacga tttatttggt gatatgatta
     2401 ttacttatat gaatgaagaa atgtttgata ttataggtta tacaaaagaa cagttttttg
     2461 gtgagatggg cggaaattta agagcaattg ttcatccaga tgatttagac tttgtttata
     2521 aaaaaagttt ggacatgatt gacacaaata aaattgaacc atttttatat agattcataa
     2581 aacgagatgg tcaaattgtc acagttatgt atacacaatg taacctttct gcaattgatg
     2641 gaaggtcgat tgcccagggt atgtatgtag atgtaaataa aataaaaaat ttaacaaaaa
     2701 tctagtacaa agtattttat tttggagaaa ttaatatgtt taaagaaatt tttttaagaa
     2761 cttttccagg atttctaatt ataagagatt ctaactacag aattatattt ataaatgata
     2821 atttaaaaaa tttaattaaa agttatatgc aagataatcc acttggaatg actaatatag
     2881 aaatagctaa gaaactccct gataatattg ctaaattttt tacggattct cacaatattc
     2941 aattagattg ggaaaaaaat tatccttatg ataaaatttc aaattggatt ttagagttta
     3001 aaaaagatac tacaagctat tggaatgttt tagaatacaa agtagatgtt gatgaaaaaa
     3061 cctacataat tactatggcc aatgatataa caaaactcta tgaagaaaat aagagaaatc
     3121 ttcactactc aattactgac ccattaactg gagcatataa tagaaaatat ttaaatgata
     3181 gatttgacat atttatagga gattatattg tactaattga cttagataat ttcaaaatga
     3241 taaatgacta tgaaggtcat aatgtaggag acaagatttt atgtgatttt gtttcacttt
     3301 taaataaaga attaataaat tctacttcta ttatacgatt aggaggagat gaatttattg
     3361 ttatattctc tagtgatgtt gacaaaaatt atgtttattc acagctagaa gccttaagag
     3421 aaaatttttt aaaagtattc tctaagtata agtatctttc atttagttat ggtgttgata
     3481 cagtaaaaag aaatttaaaa ttgacaatag ttgaattgga taaaaaaatg tataaaaaca
     3541 aggagaaaaa caagaaaaaa tttgataaaa atgattatta acattgttat tttaaaataa
     3601 attaaaatta tctttctttt tttaaacttg tacattagtt tataaatatg tatctataca
     3661 agatattgac attaagtact gaagcatata ttgtttcagt tcttttttgt taaaattaac
     3721 ttatttaaca aagatatcat agtttaacaa agcttttaat ttaaatatat tgatgtataa
     3781 tataattaaa atataatagc aaaaagaaag gaggaatatc atgagcatac tcctaaaaaa
     3841 agcacccaaa ttagcaaaac atattataac aagtttttat ataaatcgag atatcaatga
     3901 agtattaaaa tacctttgtg aaaatgttac atggattgga ccaggagaac aggaatttct
     3961 cacttctttt aatgaaataa aaaattattt ttatgcaggt caagatgaaa ttccttcttg
     4021 tgatataaat aatgatatat ttgaaactgt aagtgaagat gagaatagat gtatggtatt
     4081 aggaagatat actgttcgaa ctaaagaaaa tgctcaaatg attttagagg taaatcaacg
     4141 ttgtacattt gagataattg aggatagagg aaaattatta ataaagcaca tgcacatatc
     4201 aaacccttat ggtgaaatgc aacttgatga atactttccc actaaaattg gaactcaaag
     4261 ttatgattat ttgcaaagat tactaaaaga aaaaacagaa gttattgaaa tgattacaaa
     4321 taatatcaat ggtggcttaa aaggtagcaa tgatgatagt acatactcat ttttctatgt
     4381 caatgaggga ttgcccaaaa tattaggata cacatatgat gagttcatgg aaatgagtgg
     4441 tggttcagca gtgggtgctg tatatccacc agacttacct aaagcactag aagattgtga
     4501 acgatgtttt gcaaaaggac ctacatattc atctgaatat agaatccgaa aaaaagatgg
     4561 aacattaatg tgggtattag attctggaat gaaatcgtta aatagtgatg gcatagtaaa
     4621 aattaatagt attattactg acataaccca actaaaaaac atagaatctg aactaaaatt
     4681 agaaagagag cgatatcgta ttgctttgca aaatattaca gatatcatgt ttgagtatga
     4741 tattgaaaac gataccctta taaaatatca acgtgtagaa attgacaaaa aaattgaatt
     4801 agaaaatttt gaaacaaaaa attactccaa actattagaa tctggtaaaa ttattcacct
     4861 tgatgatatt ggaaaactac tagaagtact tcatggaaat cttcgtgaaa caattgagat
     4921 aagacaagta aattcattaa ctaaaaatga atggagatgg attcgtgttc aatgttcagt
     4981 tatatatgat agtgaccata accctatcaa aacaataggc gttttaaaag acataactga
     5041 agataaatct aaattagaaa gtttaattaa tcaggctcaa cgtgacccac taacacaatt
     5101 atataatcaa agagtatcac aaaatcttat tgaagagtat ctatgtagtt ctgattccaa
     5161 aaataatgat gctctattag ttattgatat tgatgatttt aaaactgtaa atgatacttt
     5221 tgggcatcta gagggaaatg aagttttagt tgctgtatca aaaatactat tacataacac
     5281 acatgataaa gacatagttg ctcgaattgg tggagatgaa tttacaatat ttataaaatc
     5341 attaacaaag gatttaataa taaaaattac taatgatatt ttaaatgatg cgagtaaaat
     5401 aaaagtaaag gacaatcata aaataacatt aagtattggt attgccttca ctgatgattc
     5461 aactaaatta tataaagatt tattttctaa agctgataaa gctctttatc tatcaaaagc
     5521 agatggcaaa aattgttata gtacatacga ataataaagc tatttatacg accaagaatg
     5581 aacctttaaa tttaatttca tagtctaaca atcaaagagt tgaagctaat cttatagcta
     5641 gtcaactagt tcctagaaaa aatttaaaca atatatttat tgatactgct catttttcta
     5701 aagagcaaat ttatataaaa aattaaactt ttatatacat acagatacta atgataaaca
     5761 gttatcatta gtatcttcta tcttaaaaca aaatgataat ttatctatat aaaaaagtgc
     5821 tttgttgaca gagttcactt ttttatatag gtacagaatt taagtataaa tacatgtttt
     5881 attctataca ttttagttaa tgtaaaattt cttgattgta ctctctaact tttcaacatt
     5941 atactattta tataccactt agttaatata aaactataaa agtgttgcaa ttactgggtt
     6001 ttataaagtt aatttacata ccacttagtt aatataaaac tttagcacct tatttatcta
     6061 tagagctaca gaaagtattt acataccact tagttaatat aaaacatgta tttatttgtt
     6121 cttgtactat tgttttactc tatttacata ccacttagtt aatataaaac aatatcaaaa
     6181 caaataaaaa tttttaataa atcattattt acataccact tagctaatat aaaacattct
     6241 ggtactgttg ctatttatgt tccgtattca gaatttacat accacttagt taatataaaa
     6301 ctttggagtt gttacagatt atttgcctta tctctctatt tacataccac ttagttaata
     6361 taaaaccccc aaataaactg ggcattttca atacttacac atatgcaact ctcttaaatt
     6421 tgcagtgaac catgagtagt gcaaatgata aagcttatca tataccctca acaccttata
     6481 tttcaagcgt taagctctac tttgtaacaa atatcgctca ctgcaaaact atttacattt
     6541 ttattatatc ataaatatat tatttttgaa tatctatacc aatttgtggt ataataaaag
     6601 caagaagaac tacaatctat ttagacgtag agtgaagttc aaatactaat gtttattctt
     6661 tttgaacttg atttttagtt caaaactaaa gtcactcctg cctgtgtgaa ctatacccgc
     6721 tgttttatac agttaaaaca tgtaaaaata gttataaagt actagtgtaa ctcattagta
     6781 ctctttttat tatattcata taattaatat ctatatttta aagcttacta tctaaaaaag
     6841 agcacgtcaa ataaaaccct agatatttaa tttttttaga gatacttaaa ataaattatg
     6901 ctctctctgt acttaaatat ttcctaaatt caaatggaga catagaattt aatctatttt
     6961 gatatctaaa attattatag tagtatatat aatcatctat tgctttaact aattattcat
     7021 atgtatcaaa tttccttaaa tagtacattt ctacctttaa aattccccaa aatccttcca
     7081 taggagcatt gtcaaggcaa cgaccaactc ttgtataata tatgtatatc taacaccatt
     7141 aagaaatata tattttataa tatatatttc ttcatttaat gcacttagaa aagcaaagaa
     7201 aatacagatt agtacacttt ttagagaaaa ataaaattaa tacatctaaa atattaaaaa
     7261 atactttaga taatctaaag acacatctca aagtttttaa ctaaattata aaactaatta
     7321 caaatgctat gtaacgataa taaataaaaa atttacttcg cttaagcgac gtgtcgttga
     7381 aatatttcat gttgccaact gattcataag tcgataagaa aagaacacta attatttaga
     7441 gttcttttct tagctacaag tggattataa tacttttaaa tctgtgagaa aatcatatat
     7501 aataatgata tgaacaagta aagaaaatac aaaaatgaca aaattataaa taaaatatta
     7561 taaaatcata aggtcataat tgttatattg tagaaacaaa gtaaagagag agggtggaga
     7621 ataaatgaat caaaaaaaaa taaagattag tattaaaatg gtaattatag gtatattttc
     7681 tgtaattatt gcttttgtat tatccagatt attcgttgag tatattgatg aattattaag
     7741 gtctaattgg caatatcagc tatttgaaag tgagagttca tatataatat ttgccaattg
     7801 tattatgttc tcgaatatat tattagaaat atttttaata tatatttgta gaaaatttag
     7861 aaaaatctaa tatggtcaac gtatttcgaa tcgaatactt catgattatt tagtctattg
     7921 tgctagttaa agtttaattc ccatataaag taaattgatt ttagtaaaac aaatcacccc
     7981 taagggttag tttatggata agtcatccaa atattaactc tttaattttt gctatagatt
     8041 catctttgct cataacttta cttataaaaa atgaaatatt ataagctaga acttttattc
     8101 taattctagt cataaatcct agcatagagt tacttttttt atattataaa taaaactata
     8161 caacaaagat aatatttagt aaaaataact ttcattttaa ctaaacttaa aattcaatta
     8221 ctctctaaat tgacgtttag gaattagttc aaaataaaaa agagtgtata tattgaaatt
     8281 actacatttc aatatatata ctctttttaa atttctcagt tttccatgga actttacttt
     8341 atttatttct gtattagttg tattttttat gcatttttct ttaaaatcat attttctgat
     8401 tcaactctta tattataaaa tttctttact aaattattct ctttttctat atcttcatat
     8461 atatttttta atcgcctttt acctaatctt ttatctaaca ttactaatga tttaactaat
     8521 atattatatg attttatcgc atcttctatt gagatattta aacatatatt tactgcttca
     8581 taaaaatcaa attcattaaa aaatccattt ttatttacaa tcttatatcc ctttgcatct
     8641 ctttctaaat actcttccta aatactcttc aaaactttca tcatctaatc taaatcctat
     8701 atcactatga aaaataggtt ttgcatttgg atatagttct attgttttat caaaagtttc
     8761 gaataccaag ttattattat tcgattttcc aatagtccac tataaacaat aataagtttg
     8821 ttgctccaaa taatgtaaca cttgtagaaa gatgttacag atatataaaa gatagagaat
     8881 gtagtttttc tcctaatact attagaaata gaaaaaatat gattaaaaat caaattgaag
     8941 ttttctttaa agatatgaaa ttaatagata taacaccttc tattttacag tcttatataa
     9001 ataacatata caatgagcac atgttaaatt caataaaaaa ccaagtcgat tttataaaat
     9061 cagtattgaa agaatcttat agattaaaag aaatatcaga aaatatttgt gattttgtta
     9121 caaccccaat caaaaaagta gttcaacttc taagctttat acaaaacaaa aagctcaatt
     9181 attattagaa aaatcaaaaa atattcctat aggtatacca atttttttga tgctaactct
     9241 tggattacgt tttggtgaag ctgtatcact tatatggtca gatgtagacc ttgataaaaa
     9301 atctcacatg taaatcaaac attagtttat gtatacaata aaataatctt caaagaccct
     9361 aaaaccccta tatcaaaaag aaaattattt gctcctgatg aacttataag tttgcttaaa
     9421 ggggaaaaat taaaacaaaa taagttaaaa ttacagggta tattgaaaaa tgaatttgat
     9481 ttgatatgct taaataaaag attcaacccg tgagttcaac caacttttgt tgttcatttt
     9541 aaaaaactat taagagataa taatcctaga gatataaaag tacatgaatt aatacatgca
     9601 aatgcaactt tgatattact ttcaggtact aacataaaag ctatttataa aatattagta
     9661 catgcagata taaaaatagc tatgaatata tattccatat tctcacttat tagatgaaat
     9721 gaataaagaa acatctgaaa atataagcaa aatactattc aaataatgtt cagttttatg
     9781 tcaattaaat gtcactcaaa gtgctttttt ttcatttgtc agttaaatgt cacttaaagt
     9841 acctttttcc tatttgtcag ttaaatgtca gtaatatata aataagatat atttataaga
     9901 cccttaaaat cactattatt taataaaatt tataattata tactatttgc tgttgacatt
     9961 ggtattatac catagtttat catttatatt agaaataaaa ttattaatta atagtttcgt
    10021 aattttataa tagatttaca gggagtgata gtaaatggat acaaaaatat ctataaacga
    10081 aaacatgagt ctaggtaaaa gattttttaa atacctagca ccatctgtag ttgcaatgtg
    10141 ggttttctca ctatatacaa tggttgatgg aatatttgta agtaaaggag ttggagaatt
    10201 agctttagct gctgtcaata tatcaatgcc ttttattaat tttatatttg cagtttctct
    10261 attattttca actggtgcat ctaccataat tgcaatctat ctggggaaaa aagatattaa
    10321 atctgctaac gaagtctttt catttaactt agtatcaata attatattat caataattat
    10381 attagctata acttttttta atttagatag attagcacta tttttaggag ctacagaatc
    10441 tacaattggt atggttaaag attatttagg aataataata ttttttaacg gattctttat
    10501 agtgtcttat tctttagaag ttataataaa aactgatggc tttccaatat tagctactgt
    10561 tggtgtaata atatctgctc ttacaaacat catacttgat tacttgtttg taattgaatt
    10621 tggatggggt gtaaaaggtg ctggtattgc aactggtttg tctcaagtct tttctactat
    10681 tttcttctta atacattttt taagaaaaaa ctctactttg aatttttcaa aatttagaat
    10741 tgattttaag acacttagaa aaattgtatt tataggtttt cctgattcaa ctactgaatt
    10801 aagttgtggt atagttgttt tactttttaa cttaagtctt actaaatata ttggagaaaa
    10861 tgctcttatt tattatagtg tcataaatta tataaataca ttagtactta tgactatgat
    10921 gggtataact caaggtatgc aaccacttac tagcttttat tatggtgcag gaaatataga
    10981 taatgtaaaa aaattattaa aaatggggat aaaagccaca ataatagcat cagttgctgt
    11041 atttgcaatt tgtatggctt tttcaggacc aatagtctct ttatttatac atccagaaga
    11101 aacaatgcta ttcaatgaag gagttcgtgt atttaaaata ttctctatat ctttcttatt
    11161 ggtaggaatt aatgtaataa tttctggatt ctttgtatca gtagaaaaac catcaatttc
    11221 tactgttata tctcttggta gagggcttgt aatagttgtt ttaagtctaa tttcaatgat
    11281 actaatattt ggtggacaag gaatatggat gactactatt gtttctgagt ttatatgtct
    11341 tattttatca ttagtttttc taaaaaagaa tttttctaca ttagactcta atctaaataa
    11401 ggttgcttag atgataagag tgacaatata tgaaaatatc taaataaaaa atacctatta
    11461 tacaatcttg caaatattaa acctttgcaa aaattaggat tatataatag gtattttatt
    11521 tatgtaatta ttttatttct aaatatccat agccatcttt tattaaagtt ccttttactt
    11581 catattctac aggtttttta aatattggac catctacgac aaatgtatga tactctccat
    11641 gttctccaca tgggtctgca ccagcatttt ttatcttctc cacaagttct ctagttaatt
    11701 tttttcctaa aaattcctct cctaagtgct ttaagtttac ttttgttaca acactacaaa
    11761 atccactgtc tataaattca tatactaact cctctctact ctcttgccat aatggtaaat
    11821 ctactttcat accaactgct tcacatctat cagtatccca ttttctatga ctttctatat
    11881 ctatatctcc atatgcacat atagttgctc ccatgttttt agcttttatt aaagccctct
    11941 caaagctctc ttcatatcct tctacaccac actcagcaac taataaaggt aatcctatat
    12001 tgctacttac ttgcttaagc atattatatt ctaaattatg tgtccatgac tttccatgtt
    12061 cttcacttat agttgtcaag agtgccacag gcttatatcc ttttttcaac attcgattta
    12121 atgctaatat actatcctta ccaccactaa atgacattac aaatttttca tcagccaatt
    12181 ttaacacctc tttcatctaa ctttgtttta ttaacataat tataccaaat ttttgagttg
    12241 catagcaaat tatattaaat tgttaattca ctataaagaa tgtccctaat attaaaagta
    12301 taacccctat gtatttgtat aaatgcattg tttcttgtcc caaaattacg ctatcaataa
    12361 aaaatccaac taaaacttgg gatacaagag ttaatataag tgtatttgat actcctaaat
    12421 ttggaattgc ctttactgta aaatatatta ttagacctcc aaatactcct cctaataaca
    12481 acttataatt aaaaccattt atagatacta gacactttaa gtcacctgta actattatac
    12541 ttgccaaaaa aaatattgct cctacagtta agcttataaa ggtggccact aatgctgttg
    12601 tactttttcc tagctctcca tttataaaag cttcaagagc tgtagaacca cctgctaata
    12661 atgcaaatat tattgcccat aattttgtca tggacaaacc tccttctata taattctatt
    12721 aatagaagtt tatgatacaa cctattaatt aattactaag tatagtttaa tttttataca
    12781 ctaggcttta tttggatatg aatttctgtt ataattgttc tatcgatttt ggaggtgatt
    12841 ttatgtacac aaattttaat atcgatttta ataactttaa taaaaaagaa aatgccatta
    12901 aatttatgtt aatgggagta ttactcatta tattaggatt attatgcctt acatttaaga
    12961 cattaggtat aaaattaatt tcttggactt ttggtattgc acttttattc tttgcatatt
    13021 taaatttaaa aaatattaat gaactaaaaa gatatgctac taaagaagaa attaaaccct
    13081 ctattaatat ccaatgggtt ctaataattg catgtatatt actttttgta tttcctcaaa
    13141 aaatacaaag catattttca ttatttttag gattttattt aatctttaat caactagtag
    13201 cacttgtaaa tagtaagaat aatccttatt ctaaatttac aacttggaat atagttaaga
    13261 ttctatttgg tatatgcctt atattatctc cacttttttt atctagattt atagtatcga
    13321 taatgtcttt tttcataata ttatttggac tagttctatt tttctctgga aatacagcga
    13381 gaaaatatta attattttct cgctgtattt ttatattact taaaatagaa tttgtttaag
    13441 ttatctattt gtggtaatat gttttttgta caagctcagc gtacaatttt attagaaata
    13501 ggtgattttt tggataaatt taaatatgct tttgataata aaagatatca tacttggaat
    13561 tactatctta gaaatacttt tggagaaaaa gtttttaagg tatctataaa tgcaggattt
    13621 acttgcccaa acattgatgg aagtcttggt tatggcggat gtacctattg tagcaaagaa
    13681 ggctcaggtg attttgctgg aaaccctaaa gataatctta tcagtcaatt ttataatata
    13741 aaagaaatga tgttaaaaaa atggcctcat gcaaagtata ttggctactt tcaagcctat
    13801 acaaatacgt atgctcctct tgaagtttta aaagaaaaat atgagactat attagaactt
    13861 gaagatgtca taggtctttc aatatccaca agacctgact gtttgccaga tgatgttgta
    13921 gaatacttgt ctgaactaaa taaaagaacc aatttatggg ttgaacttgg acttcaaaca
    13981 attcatgatt ctacatctaa aattataaat agaggtcatg attataaaac atttgttgaa
    14041 ggtgttgaaa aattaaagtc taaaaatata aaggttgtcg tacacattat aaatggtctt
    14101 cctggtgaag attataatat gatgatggaa acagcaaagg cagttggtaa aatgggtgta
    14161 gacggtataa aaatccatct attgcatgtt ataaaagata ctcctatgga aaagatgtta
    14221 caaaatggta tgttaactct tatggaacaa gatgaatata tcaatcttgt ctgtgaccaa
    14281 ttagaaatac ttcctgaaac tatgataatc catagactca ctggtgatgg taagagggat
    14341 gaactagtag gtcctatatg gagcctaaaa aaatgggaaa ttttaaataa aattgatgat
    14401 actttaaagg ctagaaattc ttatcagggc tgtaagtttg tttaatacaa aataataact
    14461 atagaaatgg ttatacaaat atagtccttt ctatagttat ttagtattta caaaacaaaa
    14521 tattaatttg tacatttata caatatataa taaaaaatag atagtctaaa ctgtatctac
    14581 ttatatttta tttgtactgt ccactttatt ctataaaatt tataaatagt tattttttaa
    14641 taccaaatat aatttggtat aatttttgtt ggaatctaca atgtatacca ataaatcctt
    14701 tttaagtata taattctaaa tactttcagt tttttcaatc tgctttaact tgttggactt
    14761 ataaaatatt cttatttcat cataagaaag attaagtgct actactgcag atattaacat
    14821 caacatcact ccaaataact tccctaagga aaaactttct cctaatatag tgcaaccaat
    14881 tattactgaa ccaactaatt ctactgatgc cacaacacct gcaactgaca actctacacc
    14941 tttagatata cctgctgcat aaaaaatata tgcaagtgca gctggaacaa tgcctaacat
    15001 tagcatacaa gataaaacat ctaaatcctt agcataattt aagatttccc aaggtcttga
    15061 agaaggaatc ataaatatag ctccaaataa gaaactgtat actaatattg ttgaacttga
    15121 aaattccttt aaagcatttt tactaatagt tggcataagt gcatatgcta ttgctgataa
    15181 tactccaagt aaaagcccaa aagcgtttaa accttgaaaa tccaaacgtc caccagtcac
    15241 tgccataatt gcaccaataa aacaaagaat aagtgaaaat aatttgcttc tagtaatatt
    15301 ttctttataa cataattttg aaaatattgc taaaaacagt ggtgatgtat atagtaaaac
    15361 tgctgcaatt gatacacccg caatgtcaat tgctttaaaa taacataaat taaacattgc
    15421 ctgacatata attcctatta ttactgaata tataattcct tttttgttta tctttaagat
    15481 ttgtggtgtc cttatagatg aatatacgcc taaaactata aatccaaaaa acaatcttgt
    15541 aaatgctact tgttctgatg tcagtccatt tcccattaaa aactttccaa ataatccaag
    15601 tgtagcccat aataaccctg ctattgctat aaatacatac cctttacttt tttctcccat
    15661 tttaaattcc cttctatttt tatttagtca atttacactc ttctttttaa gcaaaaacta
    15721 tgccatctta aatcaatata tatcgactct aaaaccctag tctttccaat aatactaata
    15781 aattttcaat ttttttatat ttatttttcg cttactttaa gttgatttag acttatttta
    15841 attgtaaaat gagttatata taacttattt aaagttaaaa t
//
LOCUS       DAMJWC010000083        15850 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMJWC010000083 DAMJWC010000000
VERSION     DAMJWC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15850
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.085"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            331..1347
                     /gene="gap"
                     /locus_tag="PC503_003121"
     CDS             331..1347
                     /gene="gap"
                     /locus_tag="PC503_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2529082.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1742..2911
                     /locus_tag="PC503_003122"
     CDS             1742..2911
                     /locus_tag="PC503_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529083.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYSPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3291..7544
                     /locus_tag="PC503_003123"
     CDS             3291..7544
                     /locus_tag="PC503_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2529084.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQFNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7693..8187
                     /locus_tag="PC503_003124"
     CDS             7693..8187
                     /locus_tag="PC503_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2529085.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8303..8680
                     /locus_tag="PC503_003125"
     CDS             8303..8680
                     /locus_tag="PC503_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF2529086.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            8886..9326
                     /locus_tag="PC503_003126"
     CDS             8886..9326
                     /locus_tag="PC503_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF2529087.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            9971..11278
                     /locus_tag="PC503_003127"
     CDS             9971..11278
                     /locus_tag="PC503_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529088.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    11364..11626
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11752..12555
                     /locus_tag="PC503_003128"
     CDS             11752..12555
                     /locus_tag="PC503_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2529089.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            12593..13204
                     /locus_tag="PC503_003129"
     CDS             12593..13204
                     /locus_tag="PC503_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2529090.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            13236..13907
                     /locus_tag="PC503_003130"
     CDS             13236..13907
                     /locus_tag="PC503_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2529091.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            14206..14568
                     /locus_tag="PC503_003131"
     CDS             14206..14568
                     /locus_tag="PC503_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF2529092.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            15004..15705
                     /locus_tag="PC503_003132"
     CDS             15004..15705
                     /locus_tag="PC503_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF2529093.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDELCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT         6425 a         1537 c         2779 g         5109 t
ORIGIN      
        1 taaataaaaa tttattttta ttattttaaa ttagaggaga ttcttgaaga tatattattt
       61 ttaaaaataa gtatagttta aaaattcaaa aaaaagatgg caaaatatgt cccaagggac
      121 attgagtaaa ataaatgatt tcagcttatt tacactaaaa agtacatact aaatgagggg
      181 taaaataaag aaaaatgata tactaattgt cttttgataa taaaaaaaca tggaatttga
      241 ttatttaatc aagaaaaagt attgaacaaa tgatttattt agtgtacaat aatcatgtaa
      301 aaacatagta atggagggag acatttcata atgaaaatta aggtaggaat gaacggattt
      361 ggaagaatag gaagagctgt attaagaata gctcaagaag aattaggaga taatatagaa
      421 attgtagcca taaatgcaag agcaacaaca gaatctttgg cacatttatt tacatatgat
      481 tcatgctatg gaacttttag aggtgaagta gaggcaaagg atgaagacac tctagtagta
      541 aactctaaag agataaaaat attaagatat aatgacccag aagaattacc atggaaagaa
      601 ctgggggttg atatagtaat agaatcaaca ggattattta cacaaagaga aaaggcagaa
      661 aagcatatta aagcaggagc aaaaaaagta attataacag ctccaggaaa aaatgaagat
      721 ataactatag ttatcggagt taatgagaaa gaatatgata atgaaaagca caatataatt
      781 tcaaatgcat cttgtactac aaattgtcta gctccttttg ctaaagtatt ggacgaaaaa
      841 tttggtatag taaaagggtt aatgactaca gtacattcat atactaacga tcaaagaata
      901 ttagataaaa gccataaaga tttgagaaga gcaagagcag cggctgaatc tataatacct
      961 accactacag gagcagcaaa agctgtgtca agagtactac cacaattaga aggaaaatta
     1021 aatggttttt cacttagagt accaacacca acagtttcac ttgttgattt agtgtgcgaa
     1081 cttaaagaaa acgttacatc tgagcaagtt aactctgtgt taaaagatgc tgctgaagga
     1141 gaattaaaag gtgttttagg atattgtgac aagccacttg tttctataga ttataaagga
     1201 gattcaagat catctattat agacgctcta tccacaatgg ttatagaaga caatatggtt
     1261 aaggtagttt cttggtatga taatgaatgg ggatattctt caagaactgt tgacttagta
     1321 aaatatgtag ctgaaaaatt aaaataatat atatttctta aagcaaattt taaaaaaatt
     1381 ttttaaaaaa attatataaa actaaaaaaa aagattatga aaaatattga aggaaaaatt
     1441 ttttcataat cttttttctt tcatgcaaaa agatacaagt tacaacttat atttgcatat
     1501 taggtcgtta gagaagtata tatatattta gtaaggaatc atacttttta taaaatgaaa
     1561 gataagatgt cgaaaacttg cataaatctg aaaaattttt attattaaaa tactgatttc
     1621 cattttaaaa atgataaaaa aatgacaaat aaagttgcaa atagtaatac ttataagtat
     1681 aattaaaaaa gagaaaaggt tttgttaaac tttataacaa aaaaagaagg gatgattcaa
     1741 aatggagaag ttaacagaca ggagacaggt taaggcagta agcatggaaa ccttcatttt
     1801 cctaatatta ctagtagttg gttttgggta tgttggtagt attatgggag caggaatgat
     1861 gttcaaagta ataatgagta cagcacatgc tttactattg gagacagttt tcttaattat
     1921 ggctatggca gttcttgcag gcgcattaag cgcactactt tcagagtttg gagtaatagc
     1981 gttaattaat aaaattttcg ctgtatttat gaagccttta tatggactac ctggtgctag
     2041 tatagcagga gctataacaa cttatttatc agataatcca gctattatac cttttgctaa
     2101 agataaaaca ttcacacagt attttaaaca ataccaagtt ccagcattat gtaacttagg
     2161 aacagccttt ggtatgggac ttatcttaac aacatttatg atttctcaag gtacagaata
     2221 tgtacttcca gcattaattg gtaatttagg tgcaattata ggtagtgtca taagtgttag
     2281 aataatgttg acatttacta agaagtttta taaatacagt ccggaagaag ataaagcaac
     2341 aggaacatta gagaaaaagg atgaatttag agaaatcaga gaaggaaatg tatttcaaag
     2401 agctttagat gcaattcttg aaggtggtaa aatgggggta gatatgggaa tggctataat
     2461 tcctggagtc ctagtagtat gtacattggt gatgttatta acttttggac catctacaga
     2521 ccctgttaca ggtcaagaag tttatacagg agctgcatat gaaggaataa aattacttcc
     2581 agttattgga gataaacttg gatttatatt agaaccatta tttggattta catcaccaga
     2641 ggcaatagca ttccctataa cttcattggg agctgttggc gcagcaatgt ctctagttcc
     2701 agagtttata aagtcaggag ctataactcc taatgatata gcagtattta cagctatggg
     2761 tatgtgttgg agtggatatt taagtacaca tattggtatg atggatgcat taaatgctag
     2821 acagttggca ggtaaagcta ttctttctca tacaataggt ggtttatgtg caggagcagc
     2881 tgctcacttt atatttacac tcgtaggata aatgtaatca gctaagataa aaaataatat
     2941 acaaaaaatg gttgttgata tgtaataaga atttacatat caacaaccat ttttttctga
     3001 ctaaagataa tttataatac ataaacatta agtggatatt agagttaagt tatatttatg
     3061 taaaaagtaa caaaaatctg tagaaattta tgacaaaatt tagtacacta actatatgtt
     3121 cttatttaaa atttaaggtt agaattagga attacctagt agagtaagct ttgattaata
     3181 aaagaatcat aaaataaaaa tattagtcat aaagattata aataacttac ttaaaataaa
     3241 gccatagaac ttacaaaaat taaaaaagca tataaatatg gaggggtaca atggatgaat
     3301 tatttcatat aggaattgat gtaggttcta caacggtgaa ggttgtggta cttaataata
     3361 gtaataatat agttcataaa gaatatagaa gacattattc tgatgtaaaa aaatcagtta
     3421 aagaagtact aaatggtata tatgaaaaat tgggagatat aaatactacc attataataa
     3481 ctggttcagg tggaattgga atatcaaaaa aattaggtgt aaaatttgtt caggaagtta
     3541 tatctagtac aaaatcaata gagtattttc atcctgagac tgatgttgtc atagaacttg
     3601 ggggtgaaga tgcaaagata acatatctaa gtggaggaat agaccaaaga atgaatggaa
     3661 tatgtgcagg tggcactgga gcattcatag accagatggc atcactctta aagacagatg
     3721 ccagtggatt aaatgaactt gctaaagggt ataatgttat atatcccata gcttcaagat
     3781 gtggtgtttt tgctaaaaca gatattcaac ctcttataaa tgatggagcc aatcagactg
     3841 atatagcaat gagtattttc aatgcagttg tcgtacaaac tgtgagtgtc ctttcttgtg
     3901 gaagaaaaat agaaggaaat gttgcgtttt tgggtggtcc attgtacttt ttatctgaac
     3961 ttagagaagc atttaaaaga gtattagatt taaaagatga aaacataatc ttcccagaaa
     4021 atgcacaact ttatattgct attggagcag gattattatc agtagatgaa gataatatac
     4081 aactaaaatc tctaatagaa aaattggata gtataaagaa tattgaagat ggagaagtaa
     4141 atttattaga acctttattt aaagataaaa atgagtatga agaattttca agaagacatg
     4201 aaaaagaaaa aataaattat gtggacataa attcaataaa aagcaattgt tatttaggaa
     4261 ttgatgcagg ctcaactaca actaaagcag cacttattga tgaggatgga agacttgtat
     4321 attcttatta taatagcaat gaaggaaatc cattaaaaac aaccattaaa gttataaatg
     4381 aagtatatga tatattacca aaaaatatta aaatattgag ttcaactgta actggatatg
     4441 gagaaggtct tattaaaaaa gctcttaaaa tcgataatgg agagatagag actatagcac
     4501 attacaaagc tgctaaattt ttcaacaaag atgtagattt tatacttgat attggtggtc
     4561 aagatatgaa gtgcctaaaa ataaaagatg gagtaattga taatataata ttaaatgagg
     4621 cttgttcatc aggttgtggc tcatttttag agacatttgc aagttcttta tctatgacaa
     4681 tagaagaatt tgcgcatgaa ggtatttatt ctcaaaatcc tgtagattta ggttcaagat
     4741 gtactgtatt tatgaattct agagtaaaac aagctcaaaa agaaggtgca agtgttggag
     4801 atatatcagc agggctatct tattcagtaa taaaaaatgc tttatttaaa gtaataaaga
     4861 ttagagattt aaatgagatt ggtaataata ttgttgtaca aggtggaacc ttttataatg
     4921 atttggtgct tagaagcttt gaaaaactaa ttggaaaaaa tgtaattaga cctaatattt
     4981 caggaattat gggagctttt ggttcagcac ttatagctaa agaaaaatat gaaagtggat
     5041 acaaaacatc cttgttatct aaggaagagt tgaataatat caagctagaa gcaagtgtaa
     5101 ctagatgtaa aggttgttca aatcattgtc ttcttacaat aaataaattt tctgataatg
     5161 aaatttttat ttcaggtaat agatgtgaga agggtgaagc tatttatggt gataaaaaaa
     5221 taggattaga aaagaaaaaa ccaataaatt tatttaagta caaatacaat agaattttta
     5281 gatacaaacc attggaaaaa gaagaagcaa aaaatgggga aatagggata ccaagagtat
     5341 taaatatgta tgaagattat ccattttggt ttactttttt caatgctatg ggctttagag
     5401 ttgtactttc agataggtca tcaaaacagt tatatgaaac tggtataact agtattgcat
     5461 ctgaaacagt ttgttatcca ggaaaattag ttcatggaca tatagaaaat ttaattgcaa
     5521 aaggtataaa aaatatattt tatccaagtg taacaaatga aaataaagag gattcaaatg
     5581 cagataatta ttataattgt cctgttgtaa tatcatattc tgaagtaata aaaaacaatg
     5641 tagagaatat aagaaataag aacataaatt atataaatcc atttataagt ctaaatgata
     5701 aggaaaaatt gaagaaaaga ctctatgatg aattatcaag acatttttct gatataaaaa
     5761 taactaaaga agaagttaat catgcagttg ataaagctac tgatgaacag aatttattta
     5821 aaatggagat acaagcagca ggtgaaagag cacttaaaga aataaaagaa agaaatatga
     5881 aggggattgt gttatgtgga agaccatatc atatagaccc agaaataaat catggaatgc
     5941 cagagcttat aaattcatta gatatggcag tgcttactga agactctata tgtcatttag
     6001 ccaatgtaca aagaccactt agagttgtag accaatgggt atatcattca agattgtata
     6061 aagcagctag ttttgtaaga gataaaaact atttggaact tgttcaattt aattcatttg
     6121 gctgtggatt agatgcagta actacagacc aggttcaaga aatacttaat gaaaaatcga
     6181 agatatatac tattataaag attgacgaag gcaacaattt aggagcagct aagataagga
     6241 tgaggtcctt aaaagcagct atgtttgaga gagaaagcaa aaatatagat gtaaaaaata
     6301 taaaggtaaa caggatacag tatgctaaaa ataatcagat aacgaacaaa catactatat
     6361 tagcaccaca aatgtctcca atacatttcc aattccttga aaaagctgtt aacttaagtg
     6421 gttataatat agaaattcta aaagatactg atagtagtgt aattgaagaa gggttaagat
     6481 atgtaaataa tgatgcatgt tatccagcta taatagttgt aggtcagcta ataacagcat
     6541 taaaatctgg caaatatgat ttaaataaca cttctgttac tataactcag actggtggag
     6601 gttgtagagc tacaaattat attggattct taagaaaggc tatatacgat gctggattta
     6661 aagatgttcc tgtcattgca cttagtgtaa atggaataga agatagtggt ataatggata
     6721 atatatcact aaaattaatc aatagactct ttatgtctgt tgtttatggt gatttgctga
     6781 tgaaagtact atatagagtt agaccatatg aaaaagttac tggaagtgca aatgctctat
     6841 atgaaaaatg ggttgatata tgcaaatctt ctcttgttaa agcaaaaatt tctgtattta
     6901 ctagaaatat aaaagatata gtaaaagaat ttgataattt agagatacta gatatcaaaa
     6961 aaccaaaagt aggtttggtt ggagaaatat tggtgaaatt ccatccaatt gcaaataata
     7021 atttagtaga tatattagag cgagaaggtg ctgaagcagt cgtgccagac cttacaaatt
     7081 tcttcttaag ttgtgccttt aatactatat acaaacacac tcatttagaa ggaagtagaa
     7141 agagtagaat gataggagag gcatttatat acataactgg aatatatcaa agagtatata
     7201 aaaaagcact tgataagagt gagagatttt atgctccagc caatataaaa aatgttgcta
     7261 aaagtacaga accagtagtg tcattaggta atcaaactgg agaaggttgg cttttaacag
     7321 gtgaaatggt tgaattatta aatgaaggtg tagaaaacat tatttgtatg caaccttttg
     7381 gatgtttacc taatcacata attggtaagg gttctataaa agaattaaag aggttgtata
     7441 aaaatgcaaa tataatacct attgattatg acccttctgc aagtgaggta aatcaactta
     7501 acaggataaa acttatgctt tctaaggctt ttaaaaatat ataagattta tattttgata
     7561 tgttaaaagt taatgaattt aaaaatatac tctatattaa gtatctataa aaaagagtta
     7621 tcctattttt tagggtaact ctttattagt taaaaaatta tatgtatact gatattaaag
     7681 gggggaagta atatgagttt agtatatgat gtttataaat caaaattagg aaatttgtac
     7741 atattaagtg aagatggttt tatagttagt atatacatag gagatgaaaa atttaataat
     7801 ttaaaaaatg aatgtattaa aaaaggaatt gatataaaga gaagtaagga agatttaaag
     7861 gaagcaataa gccagataga tgattacttt aatggaaaaa gaaaagtctt taatttaaat
     7921 attcgtattg aagggactga atttcaaaaa tcagtttata gggaaatgtt aaaaatacct
     7981 tatggagaaa cattgtgtta ttcagatata gcaagaaata taaacaatcc aaaatcagta
     8041 agagcaatag gacaagcaag taaaagtaat aaaattccaa taataatacc ttgtcataga
     8101 gtagttggca aaaaagatat tggtggatat atggggaatc attctgattt gaaagagata
     8161 ctattaaatt tagaaagaca gagttaactt agaaagaaat gtttttattg ttaatatttg
     8221 atataataat agtaaaaaga agtatttttt acaaaaacaa tgaagaattt attttaattt
     8281 acaaaaatga gggggaattt taatgtgtga taaagttata gcatcaaaat atcatgagaa
     8341 gggatttaat tgtgcagaat cagttataaa agcatataat gaggaattta atacagatat
     8401 accagtttgt ttaggaagtg gactgggttc agggtgtggg gttgctagtt tatgtggtgc
     8461 agtaaatgca tcaaatataa taattggata tgtaaaaggc agaaaccacg aagatgaaag
     8521 tactaaagct aaagtatatg ctaaagattt aactacaaca gtaagaaaag agtatggttc
     8581 agagttatgt atagacctaa aaaaagattt agttgcttgt agagaaataa tggatttcgc
     8641 atatgatagt ctaaaggaaa ctttaaaaaa agaattataa gaaaataagc tatcaaatat
     8701 aaattatttg atagcttatt tttatagccg atactaaata aatcaaatat attttagaat
     8761 tattatttgt aaataaacag caaataattt taggcttttt atttaatata gtttttattt
     8821 atatttattt ttgaatatgt tatactttgt ttaaataaat atttgtaatg agggagatga
     8881 gaagattgaa gaatctcaat ttacttatta ataaattata ttcaaaaaat cataatgaag
     8941 catataaaac ttttttattc ttagaaaatg aaagtttaaa atcaaatatt acatattgtt
     9001 tttttgactc attcctagaa atgattgata acgaaaactc atatattcga acaaggggat
     9061 tgttattaat ctctgcaaat gctcagtggg atattgataa taaaattgaa ataaatatag
     9121 atagtatact aagtcatatc gtagataaaa aaccttctgt atcaagaatg tttattaaat
     9181 ccatacctaa tattacaaag tataaagaaa atcttattaa tcgcataaaa atggaattaa
     9241 gtaatgcaga tataagtatt tataataata atatgaaacc attagtagaa aaggatataa
     9301 acgatacatt atctaatatt agttaaatat taatatagaa attgaatatt atctagttac
     9361 aattatttat aactaagata ataaaacaac aatggtgcta atttatatgt ataaattaat
     9421 tatgaaaaat ttatataagt aaaatatatt aacataaagg taaaattttg tatactaaaa
     9481 gggaatattt acagtttaat ggcagtttta aaataataaa ttaaagctgt catttttatt
     9541 taaaaatttt tagaaaaagt acaatagtgt taatgtgtga attagataag gtgtatataa
     9601 tagtttagat gatatgatat aaaatatgtt gtaaattaaa tgttttcttt gacaatatat
     9661 acacaaggat gataatatct atatgaataa aagatagtgt gtaatttgat aatatgtaat
     9721 tataacatta tgatataatt acaataaagt atgtaataat ctgtagaaat ttcaagctag
     9781 ttatctaagt tttcggataa ctaaatctaa acggaataca taatgtatta aataaatgat
     9841 gatactaaaa tgatactatt tttatagaaa tttattgagg tatataatta atgaaaataa
     9901 tatattaaat tatataaatt aaattatata atatattgag ttttacataa aagcaaaggt
     9961 gggaataaaa atgaaagaaa ttgctgatgc tataacatca gagtatttaa gctatggtat
    10021 caatgaagat attagtatct atgaaggtag attttgcata tatttagata aaaaatatag
    10081 atgtaatggg aaaatttatt ataaaatgac acctccaata tctataagtt ttaaagcaga
    10141 cataggttgt gttgaagaga tagacaatga agatgacaat ttagctttag attatgataa
    10201 tgctattctt gaagttcatg gatataaaat tatttctata acaataaata ctttaagtga
    10261 atttagtgta gaaggttata tcaatgatga ctgtataaaa tctaagaact cctatgttga
    10321 atatgtagat tttaatataa taaacttaga taaaatacct ggaaaactca ttaaatacaa
    10381 tgataaggta tacgcaggta gaattgaatt tgatataaat gattatgttg taactataga
    10441 caagcgatat gattatagaa aagaattaaa atcagaatta aagtctaaat ctggagcaat
    10501 aataactcat ataggcagga ttagaagaaa agatggtaga atttttagaa caaataatac
    10561 aataaatctt ttagatagga tatcaacagc tttgagtttt atgtgtggaa gatatgtagg
    10621 gttttgtttg gccaaagggt atagaagtgg taatgaagtt tatagaatat ggaatgaaaa
    10681 tcaaatatct ccttttagat atgtaccaac atggtcagat acactttcaa attatcataa
    10741 tatggaaaaa tatataagcc ttatgtgtaa aaagctagaa gatttttatt atggttctgc
    10801 tataaagagt gttgttgatt ggtacataga atctcttgga agtgctacca tggaaaacaa
    10861 tataatatct gtacaaattg cacttgaaac tttgtcatat gtaattctag tggaacaaaa
    10921 taagatactt acagatgaag catttgactg taatttggca tctaaaaata taagactctt
    10981 acttgataca tgtaagatac catatggtaa acatgaatta aatatatttg ataatataat
    11041 aaaaaataaa tttgatgatg gagtggattt agttatttat ttaagaaata gcatagttca
    11101 tccaagtaga aagactcata gagctgtgtt agaggttgaa gatatttgga atataatttc
    11161 aataggaacg agatatattg aacttgtttt actctttatt ttaggttata gaggagaata
    11221 ttcaaacaga ttagtagaaa gatgttatgg tgaagtggaa gttgtacctt ggaactagat
    11281 ttttatattt attttaaaat atatattgac atatattgcc ttatgctata aaatcaatat
    11341 cataataata attcagaata acattaaatg ctaagaaaag aaatagtaaa agtagttaat
    11401 cttaaacaga gagtttccga ttggtgagag gagcaataga ttttactttg aacacatctt
    11461 tgagcaggac tctgaaagag tagaaatact ttattaggag atttccggaa tccttgcacc
    11521 cgttatagtg ctagagtata ataattttat tgtacttaaa gaggttagtg ccgtgaggca
    11581 ttaatgaaca gaggtggaac cacgagagtt aactcccgtc ctctagcaga agctagaggc
    11641 gggagttttt taatataatt ttttaagcgc gcagagaatt atattgcaat agatacactt
    11701 tttaaaaaat aatcaaaata ttttaaaaat taaaagacga gggagaatat tatgaaaaat
    11761 atattaaaaa aagtaggaat atttacaatt atgttaggtt tattaggtgg agttgtaggt
    11821 tgttcaaaac cagataatga aaaagataag gatgcttcaa aggaatctaa aaaagaagta
    11881 gttgtagggt ttgataatac gtttgtacca atgggatttt tagatgaaaa gggagataca
    11941 gtaggctttg acgtagactt agctaaagaa acatttaaaa gacttggaat ggaagttaag
    12001 tttcagccta tagattggtc aatgaaggaa actgaattaa atgattcaaa aactgtagat
    12061 gtattatgga atggatattc tataacagac gaaagaaaga aaatagtatc atatacagaa
    12121 ccatatttac aaaataaaca gataatagtt actctaagtg actcaaaaat aaattcaaaa
    12181 gctgatttaa aagataaaga agttggaaca caacaaggtt caacagcact tgatgcagtg
    12241 gaaaaggata aagattttat gaatagctta aaaggtggag caccagttct ttatgatact
    12301 tatgataaag cacttagaga tttagagata ggtagaacta gtgcagttgt tggtgatgaa
    12361 gttttaatta gatactatat gggacaaaag ggtgaagaca aatacaaggt attaaaagac
    12421 gattttggat tagaagatta tgttgtagca acttctaaag aaaatccaga actttgtgag
    12481 aaaataaatg aaacattaaa agaaatgaaa aaagatggaa cttttgacaa gatttatgat
    12541 aagtggttta aatagaagat aagttagctg ttaagaaggg ggcactaaag gcatgttaca
    12601 aggtttagag atagttatag caatgttttg tataacattg atagtatcaa ttccattggg
    12661 gattggagtt gcatttttaa gattatcaaa gaataaatta gtaagtggta ttacacaatg
    12721 ttatatattg ataatgagag gtacaccttt acttttgcaa atgatagtca tattttacgg
    12781 attacctctt ttaggaattg tatttgacag atttacagct ggagtagtag ctttcttctt
    12841 aaattatgca gcatattttg cagaaatatt tagaggtgga atacagtcaa tcgatagagg
    12901 acaatatgaa gcttcaaaag tactaggatt tgataagttt actatgtata agagagtaat
    12961 ctttccacaa gtttttaaaa gaatactagc acctatttca aatgaagtaa tcacattagt
    13021 aaaagataca tctttagtat atatattagg attaaatgat attttaagaa tatctcaaat
    13081 agcaatgaac agggaagcaa gtctgttacc attatttgag gcaggagcga tatatcttat
    13141 atttgtagct atacttacta agggatttga attacttgaa aaaaaatatt cttattatag
    13201 ataaagttac aatattatag gaggaggttt tttatatgtt gaaaatcaaa aacttaaata
    13261 aatcatttaa aaaaaataga gtacttaaag atatttcttt tgagttagaa gaaggtcaga
    13321 ttggagtttt acttggtaag tctggtgcag gaaagaccac aatattaagg tgtataaatg
    13381 gtcttgaaga atttgatagt ggagagatta taatagataa tgaggtaata aaaaataaga
    13441 gagatatggc aaaaatacga ggaaaaatag gtatggtttt tcaaaatttc aacttatttc
    13501 ctcatatgac agtccttgaa aatataattg aatccccagt taatgttttt aaagttccta
    13561 gaaaagaggc tgaagagagg gctagagaac ttttaagatt agttgattta gaagataaat
    13621 taaattctta tccatttgaa ttgtcaggag gacagcaaca gagagttgct atagctaggt
    13681 catgtgcatt gatgccaaaa gtcctttgtt ttgatgaacc tacttctgca cttgatattg
    13741 atactattca aagagtagtc aatataatga acagacttaa agacaaaggt atgacaatat
    13801 taataattac acatgatgtt gtcttctcaa ataatgttgc agataaaatt ataagtataa
    13861 aagatggtat agtagaaaat gttcaaataa aagaaaaaat tgtttagagt tttataaata
    13921 taaactaggg tagaatttta taatataaat aaagggcaag taaaatcaaa tatactatgc
    13981 ccttttgtta tctcaaaatt taatcttata ttttatgttt aagttacatt ataatttata
    14041 ataaaaataa aaggactatt taaatatata atgtgaataa atgtttaata atttgaaata
    14101 tgataatttt ttatgttgaa agcttataat gattatgata taaattggtt atagtataca
    14161 atttatgggt ataacaataa aaaattagaa aggaattttt ataaaatgat taaattatat
    14221 ggatatacaa aatgctctac tgttaaaaaa gctaaaaatt ggcttaagga aaataattta
    14281 gaatttgaag atatagatat ggttcaaaac cctcctagta aagaggagtt aaaatcaatt
    14341 tataagacta gtggatatga tataaagaaa ttttttaata caagtggtat gaaatataga
    14401 gaattgggtc ttaaagatat tgtaaaaact gaatctgatg ataaactttt agaaatattg
    14461 gtaagtgatg gtatgcttat taaaagacca ttacttttgg atggtaaaaa tgtattattg
    14521 ggctttaaag aagatgtatg gaaaagtact ttgctaaaag aagattagga agagataggt
    14581 gtgttgatta aaattattaa ttaatacacc tataaattta tgtattaaat ctaattttta
    14641 taaatattaa ttagcaaatt caaatcaaaa aaattcatat caacaaacat attacttctt
    14701 attacaaatt atatcatatg ttttatatta aaatattata atattacaac gaattgttac
    14761 aaaattactt attattaacc atgaacattt gttttgtgct atcatattta tataagggaa
    14821 ttgtcataaa aaatatcttg ttcatacagt tttatataga aaaaagaaat gaatcttttc
    14881 tttatataag tatattttgt aaattgcctc tatatttata gtttaaataa tagtggtatt
    14941 aaaaatctga caacaaaaat aaaactttca aaaaattaaa tctaaaaaga ataggagata
    15001 aatatgagta ttgaagattt atatgatttt gaatgtgttc ctttgaacaa tgagattgat
    15061 attgatgttt tatttgaaaa gatgatagaa gatggaaaag aaaaagaata tacaccaatt
    15121 atagtcattg atgaaaaagt agggctatta agaaaaaata tagatatgat tactaaagag
    15181 tatggttctc ttgaaaacta tagagagtat tgtttaacaa aatataatga aattgatgta
    15241 aatcaatttt ttgattttag gaagagtgag atttcagaat tattaaagga gctaattgat
    15301 ttagaagatg atttttatga ttataaacat tttagaccaa ttatgaatat agatatattt
    15361 catgaatata acaaagttta catagctaaa attccaacaa ttaaaccata tgaagtattt
    15421 gcatacatac ctattggcgg atttaatgat tgtcctagag atgaagaaca tatagctatt
    15481 gcaaaatatt ggtatgaaaa gcatggaatc tttccaatcg caattggatg tgatacagtt
    15541 caatattctg taaaaaattt aactaaagat ggtaaaaaat ttgatgaatt atgtattgaa
    15601 ttagtatttt attgtgagga tattattata caagggtatg aaaccttaaa ggctcttaag
    15661 gatgtattaa aacgctctac aatagtgctt ttttggtggg attgatattc catcatttag
    15721 atagtattaa attgttagtc accaagaatc cacttgcttt agttatgggg agtgtgtcaa
    15781 actaggtttt tatacacagt gtagcatagt aatatgttta aattacaaag gttaaaaaaa
    15841 tactttaata
//
LOCUS       DAMJWC010000084        15730 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMJWC010000084 DAMJWC010000000
VERSION     DAMJWC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15730
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.086"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            231..1310
                     /locus_tag="PC503_003133"
     CDS             231..1310
                     /locus_tag="PC503_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2529094.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIVKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="PC503_003134"
     CDS             1634..2002
                     /locus_tag="PC503_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2529095.1"
                     /translation="MNVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKSLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="PC503_003135"
     CDS             2119..2922
                     /locus_tag="PC503_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2529096.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYMGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3314..4204
                     /locus_tag="PC503_003136"
     CDS             3314..4204
                     /locus_tag="PC503_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2529097.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4767..5210
                     /locus_tag="PC503_003137"
     CDS             4767..5210
                     /locus_tag="PC503_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2529098.1"
                     /translation="MIEIKTIEINKKSRIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5382..5552
                     /locus_tag="PC503_003138"
     CDS             5382..5552
                     /locus_tag="PC503_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529099.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5925..7022
                     /locus_tag="PC503_003139"
     CDS             5925..7022
                     /locus_tag="PC503_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2529100.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7227..7715
                     /locus_tag="PC503_003140"
     CDS             7227..7715
                     /locus_tag="PC503_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF2529101.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7801..8208
                     /locus_tag="PC503_003141"
     CDS             7801..8208
                     /locus_tag="PC503_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529102.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8209..8427
                     /locus_tag="PC503_003142"
     CDS             8209..8427
                     /locus_tag="PC503_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529103.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9584..9889
                     /locus_tag="PC503_003143"
     CDS             9584..9889
                     /locus_tag="PC503_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529104.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            10297..10986
                     /locus_tag="PC503_003144"
     CDS             10297..10986
                     /locus_tag="PC503_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529105.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            10986..11903
                     /locus_tag="PC503_003145"
     CDS             10986..11903
                     /locus_tag="PC503_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2529106.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAMLQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            11976..12902
                     /locus_tag="PC503_003146"
     CDS             11976..12902
                     /locus_tag="PC503_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529107.1"
                     /translation="MNYIIETNQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            12899..13579
                     /locus_tag="PC503_003147"
     CDS             12899..13579
                     /locus_tag="PC503_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529108.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            13677..14012
                     /locus_tag="PC503_003148"
                     /pseudo
     CDS             13677..14012
                     /locus_tag="PC503_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            14996..15646
                     /locus_tag="PC503_003149"
     CDS             14996..15646
                     /locus_tag="PC503_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2529109.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
BASE COUNT         6251 a         1553 c         2628 g         5298 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagccttta
      601 tcatcaagga cgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggct gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacccg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgtaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctac taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaata taaatgaatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaatca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gatagacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaattgttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gttacgaaaa aaaagaactg tgtcatctca tgtatatggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaactaca tactcattag
     2941 gtaaattatg tagtatatgt gtttacagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat atataaattt
     3061 ttaagcgaaa tacatcaaaa gaaggattag aattagtgga gacagaacag ctattataga
     3121 ttataaataa atagttttaa aggagaggta ctacgaatat agaggaaggt aaatcatacg
     3181 ttattcaagt attataaatg attagtttaa aagtactatc ggataggagt ctccatattt
     3241 aaaccttagt aaaggtagtt aaagtagtag tttaaaaact aaaaaattat ataaaggaat
     3301 taggtataag aaaatgattg agagtatacc agcaaaacaa attttacaaa aagtgaaatt
     3361 tgacaataca agatggtttg gaattgacta taatatgaat ctctatcgtg gttgttctca
     3421 tggatgtata tattgtgata gccgtagcac aatatacaac atagagaatt ttgacaaagt
     3481 tagatataaa gaaaatgtga tagaaatttt aagtaaagaa ttgcgttcaa aaagaaaaaa
     3541 aggtgtagta ggcattggag ctatgtctga cacatataat ccttttgaaa agcaactttg
     3601 tattacaaag caagcactag atttgatttc ggaaaatcat tttggagtgt ctattgatac
     3661 taaaagtagt ttggtggtta gagatatacc gattttgcag aaaattaaaa aaaataattc
     3721 tgctattgta aagttgacta taaccactgc aaatgatgaa ttatcaaaga aaatagaacc
     3781 ttatgtaaat ccaagttctg tacgatttga cgcagtgaaa gaacttaatg attctggaat
     3841 tttttgtggc atattattga ctcctatgct tccatttttg actgataata aagatgaaat
     3901 acgagcaatt gtagaaaaag cacacaaggc taatgcaaaa tttatttatt gcatgtatgg
     3961 tgtaacaatg cgtagtggtc agagagagtt tttttatgag catttaagag atatatcacc
     4021 aaaattggta cttaaatatc agaaaacata tggtttaaac tatgtatgta ctgtacaaaa
     4081 taaagattct tgtgagaagt tgttaagaga agaatgtgca cgttatggta ttttgacgga
     4141 tatgaaagat attataaaag cgtacaagag gtcggagtca tatactcaaa taaaattttt
     4201 ttaagatagg ctttggatga gatataatag tgttgattga tgtgttgata ttatagttga
     4261 ttgttagaga ggatattata gatgaatatt agtattgata ttttaggtaa ttgttagagc
     4321 tgatattata gatgaatatt agtattgata ttctaggtaa ttgctagagt tagtattata
     4381 gatgaatatt agtattgata ctctaggtaa ttgctagagt tagtattata gatgaatatt
     4441 agtattgata ttctaggtaa ttgctagagc tgatattata atttattatt agtattgata
     4501 ttctaggtaa ttgctagagc tgatattata atttattatt agtattgata ttctaggtaa
     4561 ttgctagagt tagtattata gatgaatatt agtattgata ttctaggtaa ttgctagagc
     4621 tgatattata atttattatt agtattaata ttctagggaa ttatcactat attttaaaaa
     4681 gtaaaaatat atatcaaaat gaattaaata agtactgtaa gaagtttgtt aaattaaggt
     4741 ttgaataaag tgagggtgga gaacttatga tagaaataaa aactatagaa ataaataaaa
     4801 aaagtcgaat tgacctttta atgttagccg acccatgtga agaaatgatt gataaatatc
     4861 tcaataaagg aactatgtac gcattgtatg ataataaaga acttacttgt atagcagttg
     4921 taaatgaaat ttccaaagaa atatgtgaat taaaaaacat tgctacatat gagcattttc
     4981 aaaatatggg ttatgcctca aagatgattt atcatctttt agatgtttat agtaaaaaat
     5041 attcatcaat ggttgttggt acatctgaaa gcggagttcc tttttatgag aagtttggat
     5101 ttgtttattc acataaaatt aaaaactttt ttgtagataa ttatccagaa ccaatctttg
     5161 aaggagaatt acaatgtgtt gacatgttgt atctatcata taacttttag ataggataat
     5221 atttttaggt taatataatt aattaattca tataattatc ggaattataa tttataaatt
     5281 atgtataata agagtataat ttatttagaa gctgttatat tgtattatat tcaaataaga
     5341 tatataataa cttgtttatt ttgaattttg gaggattaat tatggattca aataataata
     5401 ctataaaatc aactgttaaa aagggtattt cttttggttc ttgtttagca atgattattt
     5461 cttatactgc atggaaatct attccatggg ctatttttca tggcttaatg agttggatat
     5521 atgtacttta ttattgggtt aagtatgcat agattaaatt aataaataag tatgtaatat
     5581 tgtaaagttt aagaaacaaa atgtaaggga gtgtctcgaa gtgaactttt agtttataag
     5641 gcactctttt ttgtattaaa taaaatatat tttcattatt taaacaatga aaaagatgag
     5701 tatctctatt ttaatacata cccttatatt cattcattta tcaacaatag ttttaaaaag
     5761 aaagctatct aaaatctatt gtaatctaag tgcttctctt taaagtctta actttagtaa
     5821 tgatatataa gtttataagg ttcttatttc aataatgcaa attttactta gaagttcaga
     5881 ctttggtatg aagaaatggg taataataaa aaagaggtgt tgatatgaaa gaaaaattag
     5941 aagaaaaatc taagattatt aaaacatcaa aagagtataa acgaactata attgaagaaa
     6001 aggacagaga atggaccaaa aaattaaatg acatacttag tagaggtgat ttttctaatg
     6061 aaaaattaga taaaatcaag gatttaattc caaaagaaat attgactagt gaaaatgttg
     6121 gagaagttgt aactgaagat gggtatgcta agcctgagta tgatgaggta tttaaatcat
     6181 tgtttacttt aaataatgat tacgatttac ttgcaaattt tataaatgat atcctcaaag
     6241 atgctccata tgctaatagg aatatcaaac agttcactca aataaaaaga ataattaagg
     6301 ttgaaaccga cccaacaatt aattacattg gtgagaaaag acctagactt gatattttgg
     6361 ctgaagatga agaacgtaac catataaata ttgagatgca aagagctctt gaagaggatt
     6421 atttggaaag agctgaatat tatcttagtc gtgtacatgg tagaaagtta gaagaaggta
     6481 aagaatataa agaaattgga aaaactgttg gaatacatat actaaatcat gtaaaatata
     6541 atcacataga agattatgta aattgcctga gattaacaat ggacgggcat ccagatattt
     6601 attctagtaa aactgcatta tattttatag aacttccaaa aattcgtaaa tccagttgta
     6661 tagcaaacag agttctaata tggggtaaac ttattgataa tccttctcat atagatatta
     6721 gaatactatc taaaacggat tatgttatta aaagagcact tgatagatta aaagaattag
     6781 gtagtaatga ggactattta ttaaatttaa agagaggtgc gtatattatg aataaaagta
     6841 gaaattttaa agaagaaatt tttcaagaag gtattgaaaa aggtattgca aaagggaaaa
     6901 gagaagagaa atttaatatc atcataaaat taaaaaataa aggatacaat ttgagtgaaa
     6961 tatgcgatat tatagatgat ttgaataaat cagaggttga aaaagtctat aatcaaaact
     7021 aatactatga ttgagatggc actagataaa tacaaagctt cctcttttaa atttaaatta
     7081 atataaaact ttgttattta aatatggtag atataaagag atatataaat aataggtaca
     7141 aagaggtgta taaataaagg agataattca aaataaaagt ttgaaccatc tccttcttat
     7201 agaaaaacaa aggggttgat ttatatatga aattttatac tatacagact ttagaatttt
     7261 ggaataacaa taaaaacaat aaatatctat caaatgatta ttcttttata ttagaagact
     7321 ttgatattcc atacaaatgg atgtatagtc aaatgacaaa tagaatatat gaatttgatg
     7381 atagtatgat atgggtttgg acgaagagac ctgatttaag atgtagtggt tatttagaaa
     7441 aaggaaaaaa aggtgtttta cttgaaatag aaataagtga agacaatgtg ttattatcag
     7501 aatttgattt atggcattta cctttaatgg atattactgt agagctttat gaagatgaac
     7561 aaattgaaaa gaaggtaagc tgggaaagaa tatttgactt agaactgtgt tcaaaattaa
     7621 atgaagttaa tatagaagat ttgacattgc aaggagtgac atctaaagtg cctctatcta
     7681 atgtaaaatt aataaaagaa tttgttgcaa aataatattt ttattgaaat ttattcaaaa
     7741 aagttatata tttataacaa gaggtgttat aaatacataa ctttttaagg gggattttat
     7801 atgtctaaac aacaaactgg tattaaatca acacttattt cagaaatatt gggaatttct
     7861 tattgtattg gagctacatt agtaaataag tattttttta aaggaagtag tattgaatat
     7921 cttcctataa ttatttgggt attagctatg ggagctcagt gggtctataa taaaaagtat
     7981 gatgatttaa ttgatgaggc atcaaaatgt atactatcaa gagttaatga tattgcaata
     8041 aaagtattgt ttttttctgt agctatagta tctatatttc ttgtaacttt ggacataaat
     8101 gtgtcaaatt taaatatagg aatgtcttta ttagtcattt tgtttattca atccttgttg
     8161 aagttaattc tatttatata ttttgacaga aaggggatat acaattaggt gtcagtatta
     8221 ctaaagacaa aaattaaatc ctatagagaa aagaacctta tgacacaagg tgaacttgca
     8281 aagtcagtag gagtaagacg tgaaactatt gtacatttag aaaatggtcg ctacaatcct
     8341 tctttaaaac tggcaatgga tattgctaag gtatttgata caactgtaga agagttgttt
     8401 gaatttattg aagaaaataa tatttaaatt tcatgtatta cttatgcatt agagaatgaa
     8461 ttaattatag gtaaaaaacc aagcttatag attagagaat aaatgactta tagatgaaaa
     8521 accaagctca tagattaaag aatgaatgat ttatagatga aaaagaaagc ttatagatta
     8581 gagaataaat gatttatagg taaaaaccaa gctaatagat taaaaaatga atgatttata
     8641 gattaagaag taagctaata gattagagaa taaatgactt ataaataaaa accaagctaa
     8701 tagattagag aataaatgac tcatagatga aaaaccaagc taatggatta aagaatgaat
     8761 gatttataga tgaaaaagaa agcttataga ttagagaata aatgatttat aggtaaaaac
     8821 caagctaata gattaaaaaa tgaatgattt atagattaag aagtaagctt atagattaga
     8881 gaataaatga cttataaata aaaaccaagc taatagatta gagaatgaat taattatagg
     8941 taaaaaccaa gctaatagat tagagaataa atgacttata aataaaaacc aagctaatag
     9001 attagagaat gaattaatta tagataaaaa tcaagctcat agattaaaaa ataaatgatt
     9061 tatagatgaa gaactaaact tatagattaa aaaataaatg acttatttat agatgaaaaa
     9121 ccaaacttat agattaaaaa ataaatgatt tatagatgaa gaactaaact tatagattaa
     9181 aaaatgactt atttatagat gaaaaaccaa actcatagat taaaaaataa atgacttata
     9241 gatgaaaaat caagctcata gattaaagaa taaataactt attagatgaa aaaccaagct
     9301 tatagataag aagtccatgc ttataagcca gaaaatgaat actttaatag attaaaaaat
     9361 acatatttgt gaattataga atgaatgact ccataaacta gaaaatttat aataatatct
     9421 atataaaaat tagaagtatt ttatcacaaa aaaattaagt taaataaata tgaaattact
     9481 tccaaatata cttccaaaaa catgtaatcg catatataat ataattataa aaataataaa
     9541 tatttttata gtagtagtta attattaata aggaggggtc aaaatgccta gcatgattat
     9601 ggaagttgta ggagtactat ttatagctat tggattaatc ttgacattca ttgaaataaa
     9661 aggaaatttc ccttcttttt atggttttgg tcaaaattct atagggaaaa atgctgtagg
     9721 tattatagca gcaggaattg ctttaatttt ctttagaaat ggcatagata gcatagattc
     9781 tatagctact tatggtgtat ttttagcaat agaacttgtt gtaatagttg catatttctt
     9841 aataagaaaa aaatttacta aagaagataa acatttaaga actaattaac taaattatct
     9901 actataaaat tggaaaatta aaaacaaata aaagtttgtt tttaattatt taaaatccaa
     9961 atttgattat ttttaaagaa actatgttct gtataaaact agaatgtggt ttctttttta
    10021 tgtataaaat attttttagc aagagttaaa aggtgtttta taatataaaa tagttaattg
    10081 tagatgttaa taaaagaaaa ttatgtatat ttcagataaa gataagagag tatactatat
    10141 tttaattatt ttttcaataa agcttattga aaagaacttt aacttagaag agtatcacca
    10201 aattgcagat acaatatcat aagcagttat ttattgacaa ccctttttaa taaatatatc
    10261 atttgaagta tactgacgaa aaggagttga ataataatgg acatcttatt ggttgaagat
    10321 gataagaata ttcgagaaat ggtatacgat tttctgatta gtgagaatta ctctgttaaa
    10381 actgccattg atggaaatac agctattgaa atatttaaaa attattcatt tgatattatt
    10441 ttactggact tgatgttacc aaagtctagt ggttttgaag tattaaaata tatacgaagt
    10501 gtgagtgttg ttcctgttat tattactact gcgaaagata gtgacacaga taaaatgcta
    10561 gggcttaatc ttggtgcaga tgattatatt acaaagcctt tttcaatcgt agaattgctt
    10621 gcaagaatta aagctaatat tagacgtgca acagtgtaca gcagttcaag aaactctgaa
    10681 gatatggtta ttcagtataa agatttgatt ataaatatat caaaatatgt agtttcaaag
    10741 aatggaattg acttaaactt aacacataca gaatttgaaa ttgttaaatt actagcgact
    10801 aatcaaggac gtgctttttc aaaggaacaa ttatacaacg ctatttggaa agaaccttat
    10861 tatggaaatg aaaatgtgct aaatactcat attaacaggt taagaaataa attgtctgat
    10921 ggtatagaaa aaaataatta tattaaaact ctttggggaa ttggctacaa aatggaggaa
    10981 gaataatgga gttattttta gttgtaattt cgattgtact atttgctctc tacttaaaag
    11041 aacgaaataa atcaaagaaa atggaaagtg attataagta tatcaattca agacttcgtg
    11101 acataacaaa tgatgatgaa attaattata ttttagtacc atctgatatt tcgattgtaa
    11161 aagaaacagc agtagatata aataaacttc ttgaaaagtt ttacagcagg caaattaatt
    11221 ataatagaag tgaaaaagcg atgttgcaaa tatttacaaa catatcacac gatttacgaa
    11281 ctcccatcac agtattaaag ggttatattg aaatgttata tcttcaaagt caaaaagaag
    11341 aattatcttc ttcaatgaga gcaactgtgg aaaaaatgca aacaaattca aatgagcttg
    11401 ttaattcaat aaataacctg tttaatatgg caaaaatcca atctggagat atgatattaa
    11461 atcttcaaaa atccaatcta acacaattat gtcatgagat tattttagag ttttatgatt
    11521 tgctagataa agaaaacttt aatgttgaag ttaatattga agatagacct atatatgcaa
    11581 atgttgacac agaagcatta caacgtatac tcaaaaattt aattgataat gctataaaat
    11641 atggttcaga tggtagattt ttagggattt cactatatga aaaggaaaaa catgttttta
    11701 tagatattga ggataaaggt tcaggtattt ctgaaactga aaaagagcat attttcacaa
    11761 gagcttatac tgctgacaga aaaaaaggca atggtttagg tttggctatt tctcaagggc
    11821 ttgtaaactc tatgggaggt tcaatttatg taaatagtag acctaatgta aaaacagttt
    11881 ttacagtaaa attgaaaagt tagaaaaaag ttagatttaa aagagagaaa agataatttt
    11941 attttgtata ctgtttttag aaaggaggga gtatgatgaa ctatatcata gagaccaatc
    12001 aattaaagaa aatatataaa gataaagctg ttgttaatgc tgttaatatt catgtgaaaa
    12061 agggagaaat ttatggattt gttggaccaa acggggcagg taaaagtaca gtaatgaaaa
    12121 tgttgctaaa tcttgttaag ccaaattctg gagaaatagt tatgttcggt aagaaagtgg
    12181 cagaaactga ttttgaaata ttaaaaaaga ttggtactat tattgaaaat ccgtatttat
    12241 atgagaattt gactgctaaa cagaatcttg atttacactg tgaatatatg ggttattata
    12301 acaaagaaca tatatcagag gtattggaat gtgtcggatt gtcaaagcaa tcaaacaaga
    12361 aagtttcaaa atattcttta gggatgaaac aacgtcttgc aatagctaga gcaattctta
    12421 ctaaaccaga attattgatt cttgatgaac ctataaatgc actcgaccca gaggggataa
    12481 gagaaatgcg agaattattc cgtaagttaa atacagatta tggaataact atatttattt
    12541 ctagtcatat tctttcagag gtagaacaaa ttgcggacac tattggaatt attcaagatg
    12601 gtaaacttat taaagaaatt tctatgtcag atatacacaa atatcaaaca gattatgttg
    12661 aagtagatgt agataatgtg gagcttgctg gatacttgtt agaaaaagaa tttggaataa
    12721 aagactttaa aattacttcg gaaagttgta ttgaaatata tgatttacga aaagatgtaa
    12781 aagaaatatc caaaatattt attcaaaatc aaattggtat aaatagcatt ggacgtaaac
    12841 aaagttcttt agaagattac ttcttccaaa ctacaggtac aggaggtaaa gaaacactat
    12901 gatacattta atgaaactag agctaaaaaa agttgggcta aaaagatatt ttttattttc
    12961 aatgctgggg attttcttat gtatgttttt tgtctttact ggattgaatg ataaatctac
    13021 ttcaatatat gattatgatg ttacatttag gacaatcagt ttatttttct gtttttacta
    13081 tattatatta tttgctgtgt tgaatgtggc atatataata aatgaatata caaataaaac
    13141 aatcttgatt ttattctctt atccacttga ccgtaaaaaa cttattttat caaagttact
    13201 tttgattacg actcttatga tatcatcaat gatagttgga tatatctgtt gttttacatt
    13261 cgttgttgtg ttggataagt attttaattt agttattgga gattttcata tttcaatttt
    13321 atcttattgg ataccaggag caattaaaag tattattgta ttttgctcat taggtatatg
    13381 gacattcgtt gttggaatga taagaaaatc aatacctgtt acccttgtca gttcaattat
    13441 ttttatcaat ttaagacaat ttattttagc tggtacaaat acaactcaag acagtttgat
    13501 ttctgttttt attatagttg gtataactgt gattggtata tattatatac taaatcataa
    13561 agttactgaa attgactaga tactgtggat aggaaggtag ttattaattg tatcttctcg
    13621 ggataataat gatttgctat tatatcagct attattaata ttattagagt tttaataata
    13681 ttgcacaacc atttgaagtt gagccaaagc ttgatgaatt aattgaatgg tactatagtc
    13741 agagtgaagt atctattaaa gttataactg aatttcatta tagatttgaa ttgatacatc
    13801 catttcaaga tggtaatggt cacataggta gatttgttat gctaaaacag atgttagaaa
    13861 ataatcttcc tataaaaatt gtatcttggg atagtgagga attgtataga aactccttaa
    13921 attcttgtag tttaggtaat tatgtccctt taattgaata tttatcaagt ttagaagatt
    13981 ttagagaagt atataaaatg ttatggaaat aattgtttgc agcaaaaaaa gtttatatat
    14041 aaatgtattt ttatctatgc tatttaacgc taatttctta gttattctta gcttggacta
    14101 tacccactat tttaactata taaaatagtg gatatagttt aactatctct ttataactat
    14161 ttttatgtat cttagttgtt tcttaatatg gggacagttc ataaaactaa aagtgatttt
    14221 taattttatc atttataatt taccattaca tcagaaaaat gcttatcatt agaattttca
    14281 taaaaggtac ctattttttt caattaactg aatcaattct attagtctta atctttcata
    14341 tttcaaattg ataatataag aaaataaaaa ataaaaaatt ttaaattttt tatttattgc
    14401 gaaaaaaata aaaaggtgct atactttttg taacatatta ttcaaattat taagagatag
    14461 taaacattta tagtttaatt tgtagtacac tagcatgatt tgcagaacaa tgaattaatc
    14521 tatagtataa tagtttaatt taaagtacaa cgatttaatc tatagtacaa taacttgatt
    14581 tgaagtacaa cgatttaatc tatagtacaa taacttgatt tgcaatacaa tgaattaatc
    14641 tatggtataa tagtttaatt tgaagtacaa tgaattaatc tatagtataa tagtttaatt
    14701 tgaagtacaa cgatttaatc tatagtataa tagtttaatt tgaagtacaa tggtttaatc
    14761 tatagtataa tagtttaatt tgaagtataa cgatttaatc tatagtacaa taacttgatt
    14821 tgcaatacaa tgaattaatc tatagtataa gagcatgatt tacagtacaa taatttaaat
    14881 tgtagtacaa aagtactatc aaataagaat ttctacttta aaaatattac taaaagtaat
    14941 taaagtccag taattcaata taatatggca aaagaataga aataaggtga gagtagtgaa
    15001 agtaaagtca aatttagatg aaattttata tcataagatt attgaaagtc ttattcgtgg
    15061 tgaatactct gtaggtcaaa aaatattact aaatgacctt tgtgaaaaat ttgaagtaag
    15121 cagaacacca gttgtacaag cagtaaaaat gctaaataaa gatggagtgc ttactattat
    15181 gacaaatggt aaagtgtacg taccagagta tgaatatgat atggtaaaac aagtttgtga
    15241 aacgagaaca ctgattgaaa catatgcttt agaaaaaatg atgcaagaag aggaagaggt
    15301 ttttcaacaa aagctagatg taataaaaag atactctgat aaatgcgagg agtactatcg
    15361 tcaagaaaaa tctgtagaac ttgcactagc agatttggaa ttacataaag ccattgtaga
    15421 aggggcaaat aatgagattt taaatgatgt atatgttggt atacaaggaa gatttatagt
    15481 agtgaactat ttaattcgac cattaaaaaa tcgtaattat gaaggaacag tacaagacca
    15541 ttttgaaata ttaaaattca ttgaagacag agatacaaaa aaagcagtag ataaactaag
    15601 aaatcatatt caaggaacta ttaaaagatt ctgtgaagat gaataataag ttttgaagtt
    15661 actatatata cttatctatt aagttgctaa atgtagtcta agtataatct aattatagtt
    15721 taaacataat
//
LOCUS       DAMJWC010000085        15720 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMJWC010000085 DAMJWC010000000
VERSION     DAMJWC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.087"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..1556
                     /locus_tag="PC503_003150"
     CDS             165..1556
                     /locus_tag="PC503_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2529110.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1809..3602
                     /locus_tag="PC503_003151"
     CDS             1809..3602
                     /locus_tag="PC503_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2529111.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIAPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3683..5065)
                     /locus_tag="PC503_003152"
     CDS             complement(3683..5065)
                     /locus_tag="PC503_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2529112.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5323..5670
                     /locus_tag="PC503_003153"
     CDS             5323..5670
                     /locus_tag="PC503_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2529113.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5688..6722
                     /locus_tag="PC503_003154"
     CDS             5688..6722
                     /locus_tag="PC503_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529114.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6771..7820)
                     /locus_tag="PC503_003155"
     CDS             complement(6771..7820)
                     /locus_tag="PC503_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2529115.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8095..9630
                     /locus_tag="PC503_003156"
     CDS             8095..9630
                     /locus_tag="PC503_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529116.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9815..10501)
                     /locus_tag="PC503_003157"
     CDS             complement(9815..10501)
                     /locus_tag="PC503_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF2529117.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10626..12008
                     /locus_tag="PC503_003158"
     CDS             10626..12008
                     /locus_tag="PC503_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2529118.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12410..13678
                     /gene="eam"
                     /locus_tag="PC503_003159"
     CDS             12410..13678
                     /gene="eam"
                     /locus_tag="PC503_003159"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF2529119.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDTCDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13771..14127)
                     /locus_tag="PC503_003160"
     CDS             complement(13771..14127)
                     /locus_tag="PC503_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529120.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14278..15372)
                     /locus_tag="PC503_003161"
     CDS             complement(14278..15372)
                     /locus_tag="PC503_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2529121.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         6095 a         1931 c         2514 g         5180 t
ORIGIN      
        1 aaataatatt tttcataatt ttaaaaataa taataaaaaa atgaaaatac aggctataat
       61 ctattgagta aacatagaaa agatgatatt ataagtatgt gctaaaatgg ttaaagcaat
      121 attaatatta aatttaacta taaaacaaaa gggggcgttt ttttatgtca agtacagaaa
      181 gcgtatctaa aaaaagtggt catccgaaga gtttttggct tatttgcatg acaattttgt
      241 gggaaagatt tagttattat ggtttaacag ctttattggt attatttttt acagcaagtg
      301 tagctcaagg tggtttaggt ctttctactc aagaagcaac atctatgttt ggcttattta
      361 caggtcttat atatcttaca ccattagtcg gtggctggtt agcagataaa gttttaggtc
      421 aacaaaaatg tatttctata ggtgcacttt taatagcaat aggagatttc gtactatttg
      481 cttcatctac atctattgca atggtttggg taggtctatc aataattatt ttaggaaatg
      541 gtttttttaa atcaagttgc tcaaatatag ttggggatat atatcctaaa actgatgtgt
      601 caagaaaaga tgcagcatac agtttattct atatggcagt aaatgtagga gcatttatag
      661 ctccaataat atgtggattg ctttctgata atgtatttgc agtaagagga gcaagtggag
      721 atatagtatc ttatggatat aagatggcat ttttaatttg tggtataggc atgatgttag
      781 gtatgattat atttacactt cttgcaccaa aattattaaa tgaagtcgga aaatatcctg
      841 tgactaaagg taataaaggt gaaaaaattg agtatggacc acttactaag ttggagaaaa
      901 ataggataat agcaatggtt attttatttt tatttgtggt cttattctgg acagcatact
      961 atcaaacaca aagttctttt atgatttatg taagggataa tgtaaataga actctatttg
     1021 gatttgaaat gccagtagca tggcttacat cactaaatgc tatattatgt gtggctttat
     1081 gcccagtatt agctacccta tgggttaaat tatctcatac caaaagaggt gatttctcta
     1141 ttccagttaa aatgggatta ggaatgataa taatgggtgt tgggtttata gttatggtat
     1201 ttgctacatt agctaatggt ccagatggaa tggtaaaggc tagtatattg tttatagtat
     1261 tgacttatat atttacaaca gtaggtgaat tattcttatc tcctatagga cttgcaatgt
     1321 tcaataaatt agctccagct aagtatgcta cgttgtctat gggagcctgg tatctaacaa
     1381 gtttttttgc aagtttatta tcaggaaaga ttgctggttt tacagccaca cttggttttt
     1441 tacagatatt tggaggaata gcaacagttt taataatatt tggtttaata ttattgggaa
     1501 taagaaatgt attaacaaga ttaatggcta tggatttact aacaaaagaa aaataattca
     1561 tgacgaatta ttgtaaataa atgaattact ttaaataaag gaagttacat ttaaatataa
     1621 aattaaatgt aatttcctct ttgattatga aaaaaagctt tacacaaata gatattataa
     1681 ttaaaattat aattgtgata attagagtgt ataagattta tataaattat acaaaaaata
     1741 tttatgtaat aaactttaca tacttatata tttagttatt caaactatta tttcgaggag
     1801 gtcttgttgt gaatataaaa gatagattaa gtggattaag aaaatttatg gaagaaaaaa
     1861 atatagatgc ctatatgatt ccatcttctg ataatcacca aagtgaatat gtaggagatt
     1921 acttcaaatc aagagaattt atatcagggt ttaatggttc agcagggacg gttattgtga
     1981 ctaaagacga agctgggtta tggacagatg gaagatattt tatacaggca gaatctcaat
     2041 tagaaggaag tacaataaaa ttattcaaaa tgggacaaga aggttgccca actacagatg
     2101 aatatttata taaaaatatt cctgaaggag gaactttagg atttgatggt agagttatat
     2161 ctgctagaga aggagctaca ttagctgaaa aattatctaa aaaaggtata aagatagaat
     2221 atcagtatga tttaatagat agtatatggc cagatagacc tgctttatca gatagtaaag
     2281 catttttatt agatgttaaa tattgtggag aaagttttag ctcaaaatta gctagattaa
     2341 gagaaaaaat gagtgaaaaa ggtacttcta ctcatgtaat aactactctt gatgatatag
     2401 catggttatt caatataaga ggtggagatg ttaaatataa tccagttgta ctttcttatg
     2461 cagtaataac tttaaaagaa gtttatctat ttgttgatga aagtaagtta aatgaagaaa
     2521 tactaaatga actagctaag gaaaatgttc aaataaagcc atataatgat gtgtatgaat
     2581 ttgtaaaaaa tatagacaaa actgaaaaag ttttattaga tggaactaag cttagttata
     2641 caatttacaa taatatacct tgtgaagttg agaaagttga tgagttcaat ccagtaatgt
     2701 tttttaaagc tcaaaaaaat gaggtagaat tagaaaatat aagaaattca catgtaaaag
     2761 atggtgtagc tttcactaaa tttatgtact ggttaaagaa aaatgtaggt aagatggaaa
     2821 tcactgaaat aagtgctact caaaaattag aggacttaag aagagagcaa gaaggtttct
     2881 ttgagccaag tttcaataca attgctgcat ataaagagca tgctgcaatg atgcactata
     2941 gtgcaactcc agagtcaaat tataaattag aggcagaagg attattttta gtagattcag
     3001 gtggacaata ttatgatgga actactgata taactaggac tacagtttta ggacctataa
     3061 gtgatgaatt aaaactacac tttacttctg tagcaagagg aatgataaat ctttctaagg
     3121 ctaagttctt gcatggttgt agaggatata acttagacat actatctaga agttgcatgt
     3181 ggaatatggg aattgattat caatgtggaa ctggacatgg tataggattt gtgctaaatg
     3241 ttcacgaagc tccaaatgga tttagatgga gagtagtacc tgaaagattt gatagtgcag
     3301 ttcttgaaga aggaatggta actactaatg aaccaggtat atatatagaa ggttctcatg
     3361 gtataagaac agagaatgaa attgtagtta gaaaagctga aaagaatttc tatggtcaat
     3421 ttatggaatt tgaagttgtt acgttagctc ctattgactt agatggtata gcaccagaat
     3481 taatgaataa ggatgaaaaa gattatttaa attggtatca taagttagtt tatgataaaa
     3541 tatcaccttt cttaactgat gaagaaagag aatggttaaa agtttacact agagctatat
     3601 agtttgtact agatacaata aaaatcgagg tattataatg cctcgatttt ttattgtata
     3661 ttttattaac tttaaaaaat ttttaatttg ataattctac taatttttta ttcattataa
     3721 gtagtataat tccaaatatc aataaaaatg atggtatcac tatgaagact tgtaacatac
     3781 caagttggtc tataatagct tgcgtatagc cagataattt atttgctgca aatttgccta
     3841 aaaaccaaac acccattagg aatgaaatat acttttcagg cgaaagttta tttaccatac
     3901 catacccgac tggagaaaag caaatttctc ctatactttg gaatgttaaa aatccaacta
     3961 cccaaaatac acttgctttg tgaattgaat tagggtctgt tcctgtttgt ataactgcta
     4021 ctatcataaa caaaaatgct atggctaata gtataaaacc taagctcatt ttttttggca
     4081 cacttaaatc gcctttttta gtttgagata attttaccca tactaaagca gagataggtc
     4141 caagaataac acaaaggaga ccattgtatg aatctatcca tgaagtagga atttgaaaat
     4201 tgccaacagt aagatttatg tgttcctttg tatagagtgc aatagacata gaggcttggt
     4261 tatatgctat ccaaaaaaat actgtgaaaa aagctaacac caatattact attattcttt
     4321 ttttctcaat caaagttaaa ggtcttgaag cgagcatttt cttatattct agtgattttc
     4381 ttatagactc tctcccgtta atagggtcat tattcaaagg tttataaaac tttctgtttc
     4441 caaatataaa gaagaataaa cctattagaa ccgtaattga tgaaaataaa aatacatatc
     4501 tatatccata catacttata gataatccgc ttttcatagc aaaccattca ttagcaacta
     4561 aaccgcatat taaagggcca aataaagtac ctagattagt agccatatac gtaatagaga
     4621 aagctccatc ttttcttggg tcatcattgg tatataagtt tccaaccata gtatgtaagt
     4681 ttcctttata aaaacctatt cctaatccag ataaaaatat catgatgttt atatccatct
     4741 tactatttgc tatgtatcct agaaaataac caattgaaac cattagcatt ccaagtataa
     4801 tacagttttt gggacctaaa aatctatcac tgacccatcc accaataact ggagagaaat
     4861 aagtccatgc taaaaaagat gcaagcattg atgcggattc tgctggtgtt aaccctaaac
     4921 cacctttgga gacttgttca gctaaaaaca ataataatac caatttcata ccatagtatg
     4981 caagtcctac aaaggtaaat attgaacagc agaaatataa atctctaggt tgtttaagtt
     5041 tttcttgcgt ttttaaaact gacatatgtc gagaacctcc agataaatag tttaacaaaa
     5101 ttttaccata ctatatgagt atatgttttt ttcatataga cgtcaacttg taagataatt
     5161 taattaagtc gaaatatatg taaaaatagt atcatttttg tgtattcagt aatatttttt
     5221 tatgataata tatgttatta ttatattaaa atacaaacat atttatggaa aggatatgcc
     5281 aatttagtag ttagattgat tgtttggcag gtgggatgag ctatgataag aaagaaatct
     5341 gaattacaag tagaagtaaa agaaaattta aatggtggta taggaaaggt taagcttgaa
     5401 aacataatac aaaatgaaga gcttaaagga aaaggaagac tatttaaaag agtagcttta
     5461 ccagtaggaa gttcaattgg tgtgcatgac catacaacag attttgaagt atattatata
     5521 ctaaagggaa aaggtaaagt atttgataat ggggaatttg tagaagtaaa tgagggtgat
     5581 gtagtgtata cagctgatgg cgaaaaacat tctatagaaa atataggaga agaagatctt
     5641 gagtttgtag cactagtttt atatatgtaa aatatggagg aggagtcatg acaggcaaga
     5701 tagaagaaat taaggacaag ataaatagat tttgcaactc caatttaaat caagaataca
     5761 aagatataag ctttaaaatt ttgcaaaacc ttttagataa taataaagag ataattcatt
     5821 cttctagagc tgatatatgg tcttcagcta tactaaatat agttttagaa caaaatcttt
     5881 tatacaataa gaagcatcca ctacatataa caaaaaaaga gttttcaaaa caaataggtg
     5941 tttctttaaa tactataaat aataaatcgt ctttaataaa agatgtttgt agtattgact
     6001 ttttaaatca agatactata gctatttcta atgtagaatt ttgggtaaaa gagactaatt
     6061 ccaaatcaaa gtctgtagat ttagatttag aaaagaagaa aatactatat aaaagatata
     6121 ttaagctatc acaagatgcg aatagtgata ttgaatcaat tagatatatg gaggaagctg
     6181 taaatatagg taaaagtatg attactaaag aagataaaga acttggattt tggaaaggtt
     6241 tatctaccag agcctatatg atagcacttg aatcccttgc tagaaagtta gaaagtatta
     6301 ataatctaaa ggagtccaaa aaagtattag aatatttaat agaaattaat cctagtgatg
     6361 agcagggaat aagatacaaa ttattaaatg tattaattag attaaatgat agaacttcaa
     6421 taaataaatt atttgaactt tataaagaag aaaaatctgc tacatggatg tacagtaaag
     6481 ctctttatta ctttaaaaat aaaagtatgt ttttggcaaa tgattctatt aaggttgcta
     6541 gaagtaaaaa taagtacgtt ggattatatt tgttagattg gcgaaatgct tttggtagag
     6601 aatttgttac agaggaagaa aaggcagaag ctgtctatta ctatgatgaa aacatagtga
     6661 tttggaatga agttaaaggt tctatggatt ggctattaaa aaaaatgttg gaattttcat
     6721 aaaaaaaact actccttact tttatataag tcaaaggagt agtttttaat ttatacatct
     6781 agttttaaat cttcaggttt tattagacct ttttttctca taaattctga aatcaacaaa
     6841 gttacaatag caggaagtat aaaattaagt aaaagtatac caacccacat agatatacct
     6901 ccttttccag cactttgcat agcagttact gttccaaatt gtccaaccaa tccacaagta
     6961 cccataccag aaccaatagg aatattctcc attttgaata ttgttgtaga taatggtcca
     7021 agtaatattg aagctacagt aggtggtatc caaattttcc aattttttat tatattaggt
     7081 acttgcaaca tagatgtccc aagaccttgt gccacaaggc caccaactcc attttctcta
     7141 aagctcataa cagcaaagcc taccatttgg caacaacaac ctacagttgc tgcaccacca
     7201 gcaagaccac ctaaacttaa catcatacaa atagctgcac tacttatagg taatgtaaga
     7261 gctattccaa caagtgcaga gactaaagct cccattatta taggttgcat agttgtagct
     7321 tgcattatta tatttccaaa tgaagtcata aaagcagaaa cagctggacc aataagttca
     7381 gctacaagta ctccaattag tattgttaca gcaggtgtaa ccaatatatc tatttttgtt
     7441 tcttttgaaa ctaattttcc aacctctaca gcaaaaagtg tagcgacaaa tgctccaaca
     7501 ggtcctccta attcattacc acaagctcca acaagtgcac aagaaaatag tacaagtgga
     7561 ggtgcttgaa gtccatacgc aatagccact gctatagctg gaccagtaac ctgtttagca
     7621 agagggctta taacttcagt aaaaagagaa atattgaaat tatctcctaa tgtattgaaa
     7681 attgttccaa ttaaaaggga cgaaaaaaga ccgagtgcca tataacttag tgcgtcaata
     7741 agataccttt gaacagaaat ttcaatattt tttcttttag caaatgattt gaaatttctt
     7801 tttttataat tgatttccaa tttaaaatcc tcctcatata atataagtat aatttctttt
     7861 taattaatta tataactttt cagctgacaa gacaaatgtt atttcactaa aattagacta
     7921 ttgtaatagt aagaaattaa cattaatttt agttttaaat tttaaattta tggtttataa
     7981 ttagtatagg gatattctga aatataataa ttttccagtt tatcccaata tttaacttag
     8041 gtagattgct tacaaaacaa atgattatat attaggctaa aaggaagtgg atagatgata
     8101 tttgtaaaaa ataagaaata cagaaaaatt gccataatta tatctattcc tatattgctt
     8161 gttgcgcagt actacctttt taaatttgga atacttagac caatggtaaa gggagtagaa
     8221 attgaaattg tagatgggga atatgttaaa gatatagata aatatgtagt aaaattaaat
     8281 gaaacagtta ctttgtctac aggtgaatat attaaggttc cttcgtatgc taaaaatcca
     8341 aatatttggt ttaatgtatt ggataactca gggactttaa aaatagatgg aaataaaatg
     8401 acagcattaa aggttgggta ttcttctgtg ggtatcatga aaaattcaag agtattaaaa
     8461 aaggctacta taaaagtagt agacccagag gtagaatcac tagatatgga gattaatggg
     8521 gatttaaaac atgttggtga tagtgctact atagaaagta caatagaagt tgattatgat
     8581 aagtttaaaa aatcatataa gccagtttat aagagtagca atgaaaatat tttaaaaatc
     8641 aaaggaaata aagtaagtgc agttggagtt ggtaaagcta caatatatgc taagtgtgga
     8701 aataaagaaa ttgagagaac atttaggatt caagctagag ttgctgaaat aaatatggat
     8761 gatataaaaa tagaagttga ccagaatgaa aaattgaaac cagatataat aacttctccg
     8821 cctggtttag aaccaccaaa aatatattat gagttagtag attcaaaatt acctgtagaa
     8881 agagcaataa gtttaagtag taatggaaat gttgtagggc ttagagaagg taaagatagg
     8941 gtgagaataa cttgtggaga taaatctaaa gtaataacag taacagtagt caaagaaact
     9001 ataacgaatg actatataca aaacttggtt ggttcacata aaatagtaaa caataaagtt
     9061 attattaaac ttgaatggga ttatatgaaa gatgtctttg attatgatat atatcttaaa
     9121 gataagttgt caggagaatc atttaagaaa attaaatcta taactataaa tgaaagtgat
     9181 ttaggtaagt ctaacaaggt atatgcaact atagaagtag atatgaaggg taatcaaaat
     9241 atagattttg atatttatgt catagggaaa aaggattcag atacaactaa gccaagtaat
     9301 gtaataaata ttaccaatgg aaatggaaat tcaaataatg ataataatat taaagatatg
     9361 agggtagaaa atatatcagc taatgttgat agagataata atgtcattag agttaactgg
     9421 agtagtatat ctcataagga ctgtacttac agtatatatg taaaaaataa tactaatgga
     9481 gatggagaat ttactctata tcaaagtgat atacagggaa atgagcatac tataagtatt
     9541 cctgaaggag atttaaatct agatatttat gttgttgcaa attataatgg aaatagctct
     9601 caaaatagtg atgttataaa tgtaagatag atttgtatac aaattgaaag tgttgagttt
     9661 atttaaatat taaattaaga aaaaggatag tatagggtaa ttatactatc cttttttgtt
     9721 acaatatata ggtttaaaat ctctagtaat ataaattata aaaagtctta tttacacaaa
     9781 tctatagata ttttttttat taatcaatat tgtcttaaat tgaacttagt gcggcttcta
     9841 ttgcatgtat tactgtcgta tcaaatagtg gaatagaagt gtcattttgt ttaattaaaa
     9901 gacctatttc tgtacatcct aatataacag cctctgcacc ttgtttgcca agcttatcta
     9961 taatagataa gaaagctttt tttgaagatt cagatataat tcctaagcaa agttcattaa
    10021 atattgtgtc atttactatt atacggtctt cttcatttgg aattaagact tcaattccat
    10081 tattaataat tacattttta taaaaatctt gttccattgt atatttagta cctaataagg
    10141 ccactttttt tatttctttt tcccttaata ccgtagcagt tacatctgct atgtgaagta
    10201 atggaatatg tatactttct tgtattttat ctgatacctt atgcatagta ttagtacaga
    10261 taacaataaa atctgcccct gcctcttgta atttaattgc agcatcagct aaaattttgg
    10321 cgcttttttc ccaatttcca ctagattggc attcttcaat ttcttgaaaa tctacactgt
    10381 aaagtataca tttagaagag tgtagtccac ctaatctttc ttttattact gtattaataa
    10441 cttgataata tgtaatggta ctttcccaac tcataccacc aattaagcct atagtcttca
    10501 tattatacct ctcttattta tttattttga aatagctatt tacaaataca agtatagcat
    10561 ctaaaataga agcatacaat gataaaattg tatggagtac aattataatt aagaggagta
    10621 attatatgcc aataaattct tttgaaaact atcctatgac atggaaacca aaattagata
    10681 accgaaaacc accaatatat aaaactttag caatgttatt agaagaagat attaaaagag
    10741 gaaatttaaa tcctggagat aaactgcctc cacaacggga attagcagat tttctagatt
    10801 taaacttaag tacaataaca cgagcattta aactttgcga agaaaaggga ctaatatgtg
    10861 caaaagtggg aaagggaaca ttcatttctt ctgatgtaaa tgtaagtaat acattattat
    10921 atcaaacgga atcaaaagac ataattgaat tagggacagt tcatcctccg tatgagcaaa
    10981 atacatatat tattgacttt attaaaaatg tactaaaaca accagaaatg gataggtttt
    11041 tacaatacat gtctccatct ggcacatata tgcaaaaaaa gtcaattgca aaatggatag
    11101 aaagaaataa tgtatacacc agtgaagaaa atatattatt atctacagga gggcaaaatg
    11161 ctatatgtgc aactttacta ggattattta aagctggtga tagaattgct acagattctt
    11221 taagtttttc tggaattaag tcaatagcta aaatgatagg tattcaatta gtcccaattc
    11281 ctcaagaaaa taatgaaata tcgattgaat atcttgaaag ttattgtaaa aatgaaaata
    11341 taaaaggcat atatcttata ccagattatc ataatccaac gacacatact atgtctgatt
    11401 tatctcgtaa aaagatagcc aagatagcaa agcaatataa tataataatt attgaagatg
    11461 ctataaatag catttttaga gatggtatac aaactcccat attttcttta gctagtgata
    11521 atactatata tatttttagt acatctaaat ttttatgtgc tggtcttaga gtagcatttg
    11581 tagttgctcc aaaacgatat atagaaaatt tagaaaatgc actatataat atgaatctaa
    11641 tggtttctcc atttacagca gaaatagtac accgtttatt atattctcct attatagata
    11701 aaattataga agagaaaaga gatgcaatta tagaaagaaa tgaagttgct gataaagttt
    11761 tgtcagatta taatttgatt ggtgataaga attgcagttt tcgttggtta cttcttcctg
    11821 atgaattgga tggaaaatca tttgaaattt ctgcaaaaaa tctaggagtt caagtatatt
    11881 gtgctgaacg attttcagta ggaaactcta cagttccaaa agcagttcgt atttgtgtaa
    11941 cagctccaaa agatgtagaa gaattagaaa aagggcttaa tataataaag tcacttctta
    12001 agagttaaat ttattttact attatttaat taaataaata aaaaggcgga gaaatttatt
    12061 ataataaacc tccgctttta ttatttaatg aaatacttta ctttttatta aaaaatttaa
    12121 ttttaataat cttgaaaata taatcgtttt atggtaaaat aattcttaaa aatagaaaaa
    12181 attaatcatt tgttaaaaaa aatgcataat ttattgtaat ttattgacga aggttgaaaa
    12241 atattcataa atgtgcgaaa taacagaaaa aatgcaaaaa ttaattcaat ttcatttgtt
    12301 ataaaatcta tatggcaaaa ttaaatctgc ctatcagaat gatataaaca caccagaaag
    12361 gaggacgcta tcaaataata caagtagtta actttgatag caaaaaatta tgaatgaaca
    12421 aactagaata tccttagaga gagctgctga attaaaatca aaaattgatg attatattca
    12481 ggctagaaaa acgattaaca gaggtcttga aaaagaagaa gagataaata aacgaaaaca
    12541 gaaaatatta agtatcttaa atggaactga agaggattgg aataactaca aatggcaatt
    12601 atcaaataga ataacagatg tagatacttt atcaaaaatt ataactctaa ctaaaaaaga
    12661 aaaagaatat ataaaagagg ttggtactca atttagatgg gcaatatctc catattattt
    12721 gagtcttata gacccagaag atacatgtga cccaataaaa ttactgtcta taccaacaca
    12781 tatagagttg gaagatgaac aagaagattt ggacccaatg ggagaagagt atacaaaccc
    12841 agcaggatgt ataactagaa gatacccgga tagattaata ataaatgtaa caaatgagtg
    12901 tgctatgtat tgtagacact gtcagagaag aagaaatatt ggacaacaag attctcataa
    12961 gtcaaaagct attatccaag aatctataga ctatatcaga gaaaatgaag aaataagaga
    13021 tgtactagta actggtggag atgctcttac attaaaagat gattatttag agtggattct
    13081 tagccaactt aaagagatac cacatgttga ttatgttaga ttaggtacta ggactcttgt
    13141 tacaatgcca caaagaatca cagatgaatt ttgcaatatg ctaaaaaaat atcaccctgt
    13201 atatataaat actcatttta atcatccaat ggaaataact aaggaatcta aagaagcttg
    13261 tgaaaagtta gcaaatgcag gagttccatt aggaaatcag gcagtattat taaatggaat
    13321 aaataatgat aaatttgtaa tgagatgttt aaatcaagaa ttactgaaaa taagagtaaa
    13381 accttattat atattccaaa gtaaacatgt aaagggaaca aaacatttca atacatcagt
    13441 agatgatggt cttgaaatca tggagtattt aagaggatat acatcaggaa tggctatacc
    13501 aacatatata gtaaatgctc caaaaggagg cggaaagact cctttgcttc ctcaatacct
    13561 tgtatcaaaa ggaacagatt acgttatgct tagaacatgg gaaggaaaag ttataaaaat
    13621 ggaagatgaa cctgctgtag atataaagaa acttataaaa gaacaagcgc aggattaaaa
    13681 aagtatttaa agtttataaa aagaaacaac tttaaaataa aaagaaaatg gatgtcaaat
    13741 ttatatcaat ttgcatccat tttttattag ttatttatta ttttgttgtt gattaactaa
    13801 ttcaagatat ccacttgggt ggaagtaata tatctcagaa gtattttcat ttacaaagta
    13861 accaatatca ccatctgcat ctggtaaaaa tacataacca ttaagatttt tagcttttaa
    13921 tgcttcaaaa tcactagcat ttccttgata tatgtaatca acttcattgt tgtattttac
    13981 taaaagttct ttagcttgtt cttgagtcaa tttagtattt tggcttacag gaacattctt
    14041 ttgagaatct gcataagaag attcatttac tggtgcagtt aataacaaac aagataaaac
    14101 taataaagat ataagtgctt ttttcatact aaaaccctct ttcatgttta attatataag
    14161 attcattact taataatatt gtatgtttcc tataattaaa tattaccatt aaagagaata
    14221 atattacagt tacacagctg taacttttga ttacaaaatc gtaattaaat tgtattttta
    14281 ttccatttgt attttatcat gtctacgatt tacaaactca cagaagtata tctttataac
    14341 gcccatcaca ggagcagata gaatcatacc aggtatacca aagaatcctc caccaacagt
    14401 aactgctagg attgtaaaga atgggctaag acctagttgt ccacctacga tttttggctc
    14461 tataaatgta acttcaactt gttgaattat tattaagtaa attaaagaag ttaaagcaat
    14521 tgttggattg gagaataaat taattattac aactggtgcc atacctatta ctggaccaaa
    14581 atatggaacc atattcatga cacccataag tgtaccaaat aatagtgcat attcagattt
    14641 taaaaagtaa agaccaattc cagaaagtac tccaactata aaagaatcta aaatcttacc
    14701 tgtaaagtat ttaccaatat ttaaatttaa gctttgacat agttctatta taaagtctcc
    14761 atatttttta cctaaggaaa tataaactac tttttttgta aacagtaaga atttttcttt
    14821 ttctaataat atatagaaac aaattataaa acctaaaaga aattgtacta taaattttcc
    14881 aactgaaaat gtagtgctaa atatcccacc aagtgaacca ataagcaagt tactaaattt
    14941 aggcattaca ctcataattt tgtcaccata ctcttttaat gtattagggt caactgattg
    15001 taaactcttg cctaagtcga ataaaaactg ctctgtttta tctatgtatg taggaatttg
    15061 agcaactaaa tcagctaaac tatttactat ggatggaact gtaaataata taaacgaaat
    15121 tagtataact atgagtacac cataagtaag aagtaacgaa tatattctct taaaatttaa
    15181 tttactttct aagaacttta ctagtgggtt gaatatatat gctaatacaa atgctattat
    15241 aaatggtgtt agtagtgaca ttaataaact tatcactcca aaaaaatatt tgtaattatc
    15301 aataacttta atcaagatat atgaaacaac tacagtgagt acaatattta gataaatttt
    15361 tttatcttgc aaaataacac aacctttctt atatttatta aatttagata tacttaaatc
    15421 taagttaaag ttaatattta tagcttatta tacaataaaa agcagtatta atatagtatg
    15481 attaatatga aattataaat acgttaaaac tttatgttta tagctaaaat aataaaaatt
    15541 atttatattg tgtttatata taatctaaaa tgaaaaaaag tggtgccttt gattaaacta
    15601 agtttttata atttaaattt tgtacaataa gctatctttt attattcttt aaaatatata
    15661 tttcatttaa ttatgacaaa taaagataaa aattaaatat tttagaggtg attttattta
//
LOCUS       DAMJWC010000086        15662 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMJWC010000086 DAMJWC010000000
VERSION     DAMJWC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.088"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            76..783
                     /locus_tag="PC503_003162"
     CDS             76..783
                     /locus_tag="PC503_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529122.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            830..2425
                     /locus_tag="PC503_003163"
     CDS             830..2425
                     /locus_tag="PC503_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529123.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLMVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            2528..3610
                     /locus_tag="PC503_003164"
     CDS             2528..3610
                     /locus_tag="PC503_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2529124.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            3759..3920
                     /locus_tag="PC503_003165"
     CDS             3759..3920
                     /locus_tag="PC503_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF2529125.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            4261..5529
                     /locus_tag="PC503_003166"
     CDS             4261..5529
                     /locus_tag="PC503_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2529126.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            5724..6512
                     /locus_tag="PC503_003167"
     CDS             5724..6512
                     /locus_tag="PC503_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2529127.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSIRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            6512..6961
                     /locus_tag="PC503_003168"
     CDS             6512..6961
                     /locus_tag="PC503_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2529128.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            6965..9229
                     /locus_tag="PC503_003169"
     CDS             6965..9229
                     /locus_tag="PC503_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2529129.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            9369..9680
                     /locus_tag="PC503_003170"
     CDS             9369..9680
                     /locus_tag="PC503_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529130.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            9966..10466
                     /locus_tag="PC503_003171"
     CDS             9966..10466
                     /locus_tag="PC503_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF2529131.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            10523..11509
                     /locus_tag="PC503_003172"
     CDS             10523..11509
                     /locus_tag="PC503_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2529132.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            11559..12281
                     /locus_tag="PC503_003173"
     CDS             11559..12281
                     /locus_tag="PC503_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF2529133.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            12310..14244
                     /locus_tag="PC503_003174"
     CDS             12310..14244
                     /locus_tag="PC503_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2529134.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            14237..15505
                     /locus_tag="PC503_003175"
     CDS             14237..15505
                     /locus_tag="PC503_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF2529135.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
BASE COUNT         6231 a         1444 c         2696 g         5291 t
ORIGIN      
        1 taaaagttgt aattgtttga tatttgttat atattatata taacaaatat taaaactata
       61 atatggaggg aaattatgtt aaaagtaatc aatgtatcta aatcatataa aaataaaaaa
      121 gtagtaagta gtgtctcatt tgatgtaaat gatggagagc tttttgggtt tataggacat
      181 aatggagcag gtaaaactac tactattaaa gcaattgttg gaatacacga ttttgaagag
      241 ggagaggtac taataaattc taaatctata aaaaaacagc ctgttgaatg taaaaaggaa
      301 atggcatata tacctgataa tccagattta tacgagtcat taactggtat acaatacctt
      361 aattttatag ctgacatatt tgaagttgcc aaagataaaa gagaagagtt aataaaatat
      421 tattcaaata agtttgaact caataaagca ttaggagatt taatatcttc atattcacat
      481 ggtatgaaac aaaaattagc tataatttcg gctttgatac acagcccaaa aatcttaatt
      541 cttgatgaac cttttgtagg tcttgaccca aaagcttcct ttatattgaa ggaaattatg
      601 agggagtttt gtgacaaagg tggttgtata tttttctcaa cacacgtttt agaagttgct
      661 gaaaaaattt gtgataagat tgccataata aaagatggaa atataattgc ttatggaact
      721 acagaagaag ttaagggaag taattcactt gaaagtatct ttatggaatt aatagagaaa
      781 taaaatgttt tttatacaat atagtgtcta aagtgaggaa tgataaaata tgagcaatct
      841 aagtatatta ataaaaacta atataataaa tgaatttaaa ttaaatgcgt taaaaaaagc
      901 tgatggtaga gaaaaacaaa aaataatggg aatgatgctt tcagttgtta taatagcggg
      961 tctattaatt ttttatgtaa caagcttaag tctctcttta gttgatatct taaagcaaat
     1021 aaatcaactg gaaatgctac tgatatttgg ttttggatta tcaacattaa caactattgt
     1081 tacatcatta tataaaacgt catcatatct atttcaagca aaagatttag accttttgac
     1141 tagtttacct ataaaagaat ctactgtact agcaagtaag atattaatgt tggttggagc
     1201 aaactattta ttttcttcaa tatgtatgat tatacctgca gtggtttact ttttaaattc
     1261 tgatgtaagt ataacttatt tcccttattt gatattgcta tttttagctt taccattatt
     1321 accgatagtt gcttcatcaa taatttttct atttataggg cagatatcat caagaataaa
     1381 atacaaaaat ttagtattaa tcataggtag cattatattg atgttgcttt ataccctact
     1441 tatgtcaaga cttaattcta tgtcagttga aatgctaaag aatagtgtgt ctatttcaga
     1501 gacaattaga aaagtatatc ctcctatata ttattttgtt gatgctctta aaacaggaag
     1561 tatagtttca tttttagcat ttatagccat ctcaataata ccatttttta tgtttgtaac
     1621 tctatttgca aaaaaattta aagatataaa tgctaagatg agtgaaggat ataagtcaaa
     1681 aaattatgaa tttaagggtc aaaaaacttc aagaccttca aaagctttat taaaaaaaga
     1741 atttaagaga tatacttctt cgtttatata ctttttaaat tcatctgcag gtttgttatt
     1801 tctaatggta ggtacaattt taatattatt atttggagca gataaagtgg gtgagttact
     1861 gaaattgaat atagatttta atcttataaa aatacaatta ttgggagtat tcttctttat
     1921 aatagtaatg aattgtacaa catactgttc aatttctctt gaaggaaaaa acttatggat
     1981 actgaaatct tctccaatag atgaaagaga aatattctgg tcaaaaatat tgatgaattt
     2041 tttattgaat gcaccactat ctattttatg tctaatatta gtatctataa gattagactt
     2101 tgaaattcag tttattattg tatcaatctg tttgattgta agtttttcaa tgtttgtagc
     2161 attgatggga ttattatcaa atttattata cccaaacctt gattggaaaa atgaggtggc
     2221 tgtagtaaaa agaagtgcaa gtatgatagt tacaatgtta gtatcattag cttatgtaat
     2281 tatacttgga ggtatatatg tattacttgg aatttcgttt ttaaatatat atattatttt
     2341 ggcaagtata cttactttga tattagattt tatgatatgg agaattattt ctactaaagg
     2401 agtaagaata tttaaaaatt tataggtgta tttatgtcaa ataaagactt atctttttta
     2461 gtcttgcaaa taataggtta agtagtatac tatgtatagt gatatgaaaa aatttaggag
     2521 aaaataaatg agaaaattat ccaaaagaga aaaagatttt attcaatatg gatttttatt
     2581 atttttgata tgtattacta cttatttagt attaactact ttagatataa aactaatacc
     2641 taaaattata aggctagtaa ataagactta tatatttctt ggcatattga caattatagt
     2701 atatatgata attgaatcta ttgtaactca tttgataata aatgcagttc aaaaaacaaa
     2761 agtaaaattt attggtatta aaatggctac aatgggattt tactataact tagttactcc
     2821 atttgcatct gggagtcaac caatgcaaat atatgcactt acaaaatatg atgtaagcct
     2881 tagtaaatca gtggctatag ttactaataa aactgtagta tttcaaagta cagttactgt
     2941 attttgtgga attttaattt tgctaaataa gtcattactg atggagcaag tacattctgt
     3001 gaaagtcttg ataacttttg gaatgattat gaatgtaagt atgttgttag gtggactact
     3061 aatagtattt agtccaaaac aagtaaaaat gatagcagaa gttttgatta attttttatc
     3121 taaatttaaa acatttaaat ttttagattc aaaacgtgat agaataaatc attatattga
     3181 tgattataat tattctataa aaatatttat taaaaatgta agaatcttag ttttaagtat
     3241 attacttact gtgttacaat taatcgcata tttcagtata gtttattgtg tgtataaagc
     3301 ctcaaattta agaggagttt catatgtaca tataatgaca ttacaggtct ttttatatat
     3361 ggctatatca ccaattccaa caccaggaaa tgttggagct aatgaggtta cattttttac
     3421 tatgttctcc aatataattc caaaagaatt attggggtac tctgtactct tatatagtgg
     3481 gtttgtatac tattttatat taatagtttc aggtttattt acatttggaa cgcattatac
     3541 attaaattct tggaaaaagg aaaataaagt aaattctaat ttagataagg ttattgaaaa
     3601 attaaattaa taaaataatt agggaaattc tatatataaa tatggtgttg aataagctat
     3661 attatattga gatatttccc ttttttgatt aaaattatag aaatttgaaa taataagtaa
     3721 taaacagaaa aagtgatatt gttttgaaag gagaaactat gaaacaagat aaacaaaatg
     3781 aaaaacaaag tgagatttct aagataaaac aaagcaatga taataaactt gaaatagctc
     3841 aagaattaca tgtaagtaaa aatataggga atatgcttgg atatagaata gataagaaaa
     3901 aaatgaatag accaagttaa tgaaaatgtt gaaaatggta cattttaaaa aatatatata
     3961 atgaaatgtt ttattgttaa atttaaactt attttaatgg gggaaaaagt cgaaaaatat
     4021 ctaaaaagat atggatataa aaaatattaa tatatatata ctataaactt gacaaaatca
     4081 accttttaat aactagcaaa aaatagcaaa attatataag cgttatttaa ttgtcaaaaa
     4141 tgaaagctaa attgcatgtc ctaaaaaaaa tgattgataa catttatttg tgtgctataa
     4201 ttatatagta aaacaataag tatattgcat aatgtatgca aatcgggagg agagacggac
     4261 atggaagcat ctatacacac aattgccagc aataatttat tgataatttt tgctattgta
     4321 agtataactg gaataatttg tagtaagctt agtgaaataa taaaggttcc agatgtagtg
     4381 ttatatttac ttgtaggtat tttaatagga ccatcatttt taaaatttat agatattcgt
     4441 ggatttcaaa tagaaaatca actaatactt acatttggtt ctgcatttat tttatattta
     4501 ggtggaaaag aaataagttt aaaagtattg agaaatgtga agatatctgt attcttatta
     4561 gctactttag gagttgtgat atctgctttt ataatgcaac aagtaatagg atttactttt
     4621 gggataagtg caatgactgc tttactagca ggaactataa tagcatcaac agacccagcc
     4681 actcttgtac ctatatttaa tcaggtaaag ataaaggata gggtaaaaca aactgtaata
     4741 agtgaatcag cttttaatga tgcaacagga gctatactaa catcagcagt gttggctgta
     4801 attttgtcaa ataaattttc attaggtgaa aatatttatg aactggggac aatggttatt
     4861 gtcggagttt tagttggttt aattacagga atactgcttt tgaaattagt taatgataaa
     4921 ccttatggaa tatttaaaga ttttgcacca ataatatctg ttatttcagt tgtagttgca
     4981 tatgaattat ctacaaaatt aggtggaagt ggatatatgt cttgctttat tgtaggtata
     5041 ataactggta acaagaaaaa ttttaaaatt tggttaagtc aaaaatctta tgatgcagat
     5101 ttttatgttg ctgaaacttt aggtactatt tgtcgtatgg caatatttat aatattgggt
     5161 agccaagtta atttggctca gttaagtaaa tattttatgc catctgtaat tacagtatta
     5221 gtattaatgt ttatagcaag accactttgc gttttagttt gtacacttgt agacagggaa
     5281 gcaaaatgga gtaaaagtga aatattattt atgatgtggg taagggaaac aggcgtaata
     5341 ccagcagcac tttgtggtat tatttcagca atgaaagttc ctggatacga agtgatttca
     5401 tctgtagtat tcatgactat actaattaca ttagtaatac aaggaagtac tacaaaatta
     5461 gtagctaaaa aacttggatt attagaagaa gaagtgataa atataagtga aaaagtatca
     5521 actttttaaa gttttgcttt aaaatagtac ctgttaatgg ctattttaat attgtctaat
     5581 gatgattatt gaaatagtca tttttttatg tataagtaat ttacagaatt tacatattag
     5641 acatatttat tatcaaaatt tgttgaagct atgatataat tagttgtatt taaaataaga
     5701 atagcaaata agggaggaaa tttatgttta cggttatgga tattgtacag ccagatacag
     5761 tagaagaagc gtactcaatt ttaaataaaa gaaaaactaa ccaagtaatt ggtggaagtg
     5821 cttttttaag aatggggaaa aaaagaatag gaacaggaat agaattatct aaattaaatt
     5881 tagattatat aaaagagtat gaagattacg ttgagattgg ttctatgact acttttagaa
     5941 cattagaaac aagttccata ataaaaaata attttggaag aataatagaa gattcagtta
     6001 aaaatataat aggagttcag tttagaaatg tagtaacagt tggtgcaaca gtattttcta
     6061 aatatggttt ttctgacttg atagtagcat tactttcatt agatacggaa gtagaattat
     6121 ataatattgg gagaattagt cttgaagagt ttctaaatag agattatgag aaagatttac
     6181 ttattaagat atacataaag aagacaaata agaatgcttc ttataaatca attagaaatg
     6241 caaagagtga ttatccaatt ctaaatgtat ctgtatcaaa acatatggaa caatttaagt
     6301 tatgtgtagg agcaagaccg cagaaagcta cgattgcaaa acaagctagt gaatttctat
     6361 ctaacaatga aatcaatgaa attaatatag ataaagcagt agaaatagca tcagaagaac
     6421 taacttttgg ttctaacatg agagcatcta gggagtatag aaaagctatg agtaaagtac
     6481 ttttaaaaag agctataatg gaggttattt aatgttagta aagattaata taaatgggaa
     6541 gaaaaaaagt gttgatatag aaccagaaga atatctggtt gatactttaa gaaaagttgg
     6601 taatttaagt gtgaaaagag gttgtgacac aggttgttgt ggtttatgta cagttttaat
     6661 tgacaagaaa cctacattat cttgtgcaac actgacattg agagctttag ataaagaaat
     6721 aactacaatt gaaggtttag aaaatgaagt taaagaattt agtgaagttt tggtaaaaga
     6781 aggagctgag caatgtggtt tctgttctcc tggctttata cttactgtac ttgcaatgaa
     6841 ggatgagctt gaaaatccta cagatgatga aataaagcat tatcttacag gaaatctatg
     6901 tagatgtaca gggtatatgg gacagttaag agctatcaaa acttatctgg aggtaaaata
     6961 gaacatgaat atagttggaa aaggaatcaa gaaaatagat ggaatgagta tcacaacagg
     7021 aaagcctgta tatacagatg atttatcagc aaaagatgct ttggtggtaa agatacttag
     7081 aagtcctcac gcttatgcaa aaataaaaga tatagataca tcaaaggcag aaatggttga
     7141 tggtgttgaa tgtgttttaa catataaaga tgtaccaaaa tctcgattta cacttgctgg
     7201 tcaaacatat ccagagccat ctccatatga tagattaatt cttgaagatg ttgtaagata
     7261 tgtaggtgac gaagtagcta tagtggcagc tatagatgaa aaaactgcaa ttaaagcaat
     7321 gaatcttatc aaagtaaagt atgaagtact tacacctgtt ttggattttg aagaggcaat
     7381 aggaaataaa actatggtac atgatgaaga tagacattgt aactttgata taggtatgca
     7441 aagagaaaaa aatatagtat cccatcatga ttatacaaaa ggtgatgtag aaaaagtatt
     7501 aagtaattgt gatgtagtga ttgaagaaac ttattatact caagctcaag cacatgcaat
     7561 gatggagacg tatagggcat acaattattt agaccatatg ggaagattgg ttgtagtaag
     7621 ttcaactcaa ataccatttc atgtaaaaag acatttatct cgtgcactag aaataccagc
     7681 tagcaaaatt agggttataa aacctagaat tggtggcgga tttggtggta aacaaactgc
     7741 atgtgttgag attttttctg caattgttac tttaaaaaca gggaaaccag ctaaaataat
     7801 ttatgataga aaagaaactt ttaattgttc aacaagtaga catgcaatga gattaaaagt
     7861 tagactaggt gctacaaatg atggcataat aaaggcaata gatataaaag cactttctga
     7921 tacaggagca tatggagagc atgcttctac aactattggt ttggttggag aaaaaacttt
     7981 accaatgtat aataaagttg aagcaacaag atttattgca gatgtggtat atactaataa
     8041 gatgccagca ggagcactta gagggtatgg agcatcacaa ggatgttttg ctgttgaatc
     8101 aactataaat atgcttgcta ataaattaaa aatggaccca acagatttaa ggttaaaaaa
     8161 tgtggtaaca gaaggtgaaa ctacatttgc atatggtaaa actttaaata gtgtcgattt
     8221 aataaaatgt ataaataaag gcaaagaact tattggatgg aatgaaaaat atccttgtaa
     8281 acatcttgat aatggaaaaa ttagaagtgt gggtatggca attactatgc aaggttctgg
     8341 tatacaaggt cttgataagt cttcagctga aataaaattg aatgactgtg gagattatac
     8401 tcttatgata ggttctactg atatgggtac aggaagtgat acaattttag ctcaaatggc
     8461 tgctgaggtt cttgatacaa gcattgaaaa tataacagtt atatcagctg atactgactt
     8521 agttccatat gacccaggtt catatgcttc aagtactact tatgtaacag gtatggcagt
     8581 agttaaggca gctcaagact taagagaaaa aataatttct gctggagcaa ctaaactagg
     8641 tgttgagaag gatgaagtag aatttgatgg tataaaatta actagtaaaa aaggtagcac
     8701 tttattattc gatatagcag ttgattctac aattggtcca gatactaatc aattaatagg
     8761 tcttgcttct catggtagcc cagtatctcc tccacctttt atagcaggtt ttgcagaaac
     8821 tgaaattgac acagaaactg gaaaagttga tttagtaaat tatgtagctg tagtagattg
     8881 tggaacggtt ataaataaaa atctagctaa gatacaagtt gaaggtggaa ttgttcaagg
     8941 gattggaatg gcattatttg aagaagttag atacacagaa aaaggaagca tggacacaaa
     9001 tacatttatg caatacaaga ttccagctag atgtgatatt ggaaatgtta aagtagattt
     9061 tgttgaaact tatgaaccaa ctggaccatt tggtgctaaa tctgttggag aagttgttat
     9121 aaatacacct ttaccagcaa tacaagaagc tgtgtttaat ggaattggtg taagaataaa
     9181 tacactccct attacacctg aaaaagtttt tatggaaatg aataaataat tatttatgaa
     9241 aatttagact agttttacat gttaaacaac cagttatgtc atacctgttg aaagatattt
     9301 aataagtagt tattataata ttatgaattt tacttataaa atacaaaatt aaataagggg
     9361 atgatgtttt ggctggtaat ctaaataata tgagagcagt aaataatttt agaggagata
     9421 agaacatttt agaatgttta gtcagctttg agggtcgttc aataagtcag agaaaagtaa
     9481 gggtattttt taaagaaaaa caaaatcaaa tagaaattga ttttgcagaa gaggaaattt
     9541 ctaaattggt tgaaaatgtt gttttaaata catcatatca agaaatgtta tatgatgaaa
     9601 tagagaaaca actggaaatt gattgtatag gtacttggat gatattatct aaattaaaag
     9661 atggtagtag agttcactga ttttaaaata aattattaga gcctaatttt aaggctcttt
     9721 tttgctgttt ttaattaaca atagaaaatt tatctttagt ttgtatataa ttttaatatc
     9781 atatattcta tatatataaa attgaatttg tatgtattat attgtataat ataaaatgaa
     9841 ttgggaaaat agttcgctaa aataatttgt ttttataaaa ttactgttta agtttataga
     9901 ttttgtataa aataaagtta tgttattaat ttttttaaaa ataaaacttt tactaggaga
     9961 cagatatgag aaaaaatagt attaatatag cactaactgc agcaattaca gcaatctatg
    10021 cagttttaac attatcattg ggatttataa gttatggacc aatacaattt agggtagcag
    10081 agattatgat gcttttggca tttttagata aaggatatat agtaggtctt acattaggtt
    10141 gttttttagc aaatgtaata ggaccatatg gtgtacctga tataattttt ggaacattag
    10201 ccacatttat aagtgcaagt atgatttata ttactagaaa gttaggtaaa caaaataaaa
    10261 gtactttagt tatagcttct ttatggccaa ctgttataaa ttcgattgtg gttggtctaa
    10321 tgttaaatgt attctttggg cttccattaa ttctatctat gatacaggta ggttttggag
    10381 aatttgtagt agtaacaatt gtaggagtac catttttctg ctttttaatg aaaaaatata
    10441 aaaatgtcat taatattaaa ttttaaatag tgtatagtaa tttaattaat tgagagtatt
    10501 attagtgaaa agaggtgttt atttgtcgaa ggtaaaaaga ttgactgatg tttggatata
    10561 tattaatgat aagcaaaagt ttacaataaa agagttgtca gaggaattta atctttcagc
    10621 taaaacaata caacgatatt taaaagaatt aaataaaatg ggacttccaa ttcaagcaga
    10681 acaaggtaga aatggaggtt atagggtgct aaataatagc tatatacctc ctgttatatt
    10741 tacagaaaaa gaagttatga ttatactatt tgcacttaag tcacttcaga tttataatta
    10801 taagttaatg gaaatagaaa ttaattctat aatgagaaaa gtaagttatg aacgtaaaag
    10861 cagtataaaa gtaggtatag aaaatattaa aagatacatt ggctttgtag ctaatgatac
    10921 taatgatgga gattttaaga gtagtaatgt aactgagttt tttagagctt cttcagaatc
    10981 tctaatttta aatattaagt ataagtgtgg taatcagatt ttggaaaaaa acgtatgccc
    11041 tataggtata tatttaaata agggagcatg gttttcacca gcatatgatt gtaaaagtga
    11101 taaaataata ttagttcata tagataatat aattgatata aaaagaacag gagaaagtaa
    11161 aaaaatacat ataaacttgg aagaatggtt acatgaagta tataacaatt tatatggaaa
    11221 tagttcaact actaaaaaat ttggtgaaat tatttatcta aatgtattat taactaaaga
    11281 aggtgtttct aaaataaagg acagttcttg gaatttagat atggagctaa atgaagatgg
    11341 tagtggaata attagtacat tcataaaggt tgaagatata gattgttatg cttcgatttt
    11401 attttttatt ggaaataatg ctaaggttat agagccaaaa tttttgaata agctacttta
    11461 tgataaggcc aatgagttaa gatattttta tgaagaaaat atggtataat atttagaaat
    11521 gttgaaatta aataattatt aaggagatat acgttataat ggaaaatttt aataagaatg
    11581 ctaaaataat tggtattgga gctgaaggta ttaatataat aaatgaagta gaagaaaaaa
    11641 taaaagcaaa tatggatata gaaaaaataa acataaatca agagattgaa aaagaatatg
    11701 ttagaagtct tttagatggt gtagatatat tatttttgat atattcatct gaagataaac
    11761 atattagaga tattataaaa gctgtttcat atatgtcaaa cgaaagaaga gttctatcta
    11821 taggaatgga ttgttcagag aaggaaaata aagaagattt agagcttggg agagagttta
    11881 aaatcaataa tgatagtata tttaaatttg ttgatttaat gaatatcatg gtagagtcta
    11941 tttctgattc ttgcatgata aatatagata ttactgattt aaaagaagct attgtaggag
    12001 ataaaggaat taagtattct tttgaagagt ttgaagatac aaagtcatat agcgagatag
    12061 ctgacatttt atttgacagg atggaatata ttggtgagga atttataagt aagaaaggaa
    12121 ttgtatttgt tgaaggaagt ccagaatttt ctataatgga attgaatgat ttaataagta
    12181 atattcagag caaggtagaa gaaagctatg aagtaatatt ttctttatat ataaaggaaa
    12241 atttaaatgg aaatattaga gtaggcttat tgtataatta gtatatttta gatattaagg
    12301 agagtgtata tgtctgaaaa tataagaggt acagagtatt ggttaatgga agaatttttt
    12361 tatcaggaaa cagacacacc acagattttt agagaagaaa gcataattgc acttggattt
    12421 gatataaaaa taaatttaaa aaaagtattc agtatgggga aaaaatcaga aaagtatatt
    12481 aatgagaatt gtaatgataa agattttata aaaaagttta tgtcgattaa aaaaggagat
    12541 tattttttat ataaagcata tcaaaatata gaagaaaaag ttaaatgtaa tgtgtctatt
    12601 ggcatagttg aagaagattt tgaaaatgga tatgaattaa gtcatatttt agggcataca
    12661 ctaccagtaa aatggatgca taattttgat acagtttcaa attgtaaagt atatacaagt
    12721 gaattttata aattaaataa taatgatatt agttcatatt tagaaattat taagtcacaa
    12781 gataagaaat tattgagaaa aagaatagaa gaaagtgaaa ataataaatg gtatttaaaa
    12841 aactattatt ataaaaatgt agataagtgt gtagatgatg aagaattatt tattcagccc
    12901 attaatctag aacaattaga aagcctaaaa aatataaaga cagatgatta tattttattg
    12961 tataatagcg agaaagtaat ttgtgaaaat gaccatacaa tgaagagtct atttggcgta
    13021 tgtcaagtta tggaagggtt cgataaagag aaagtaagtg ctttggaggg tggatatttt
    13081 tttcctgtta gatggataga gtatgaaaag gagaatatag acggaaatgc atgggttata
    13141 tttgaaaata atagtatagt tgaaaagtat gtaaaaagat ttactaataa aatgccatta
    13201 aatactatac tttatggacc accaggaact ggtaaaacat acaatacaaa acagatggtt
    13261 tacaatctag taagtgaaac cagtctaaga aacagatact atacaggtta cttagattat
    13321 aaaaataatg tagaattttg tacatttcat caatcatatg gatatgagga atttatagag
    13381 ggccttaagt ctgatggtga aggcaatttt aagccagaag atgggatatt aaaggatata
    13441 tctatagaag catgttataa tgcattgaaa tttgaaaaaa agatgagctt tgagttggaa
    13501 aaagatagct tgactttaga aactataaaa gacaggaaaa agaaattagt attagaaaat
    13561 atagaatata gtgagagttt taattttgaa gaatcagaaa actatgtttt aataatagat
    13621 gaaattaata gagggaatgt atctaaaata tttggtgagc taataacatt attggaagat
    13681 gataaaagac ttactaaatc aaatcaaact attgtcaaac taccatattc aaaggaaaaa
    13741 ttttctctac ctccaaattt gtatatagtt ggaactatga acacatcaga taaatcaata
    13801 gcacttttag atatagcttt aagaagaagg tttaattttg aagaaattat gccagattat
    13861 gatttattgt ctattgtaga tggtatagat attagaaaaa tgctatatac aatcaataaa
    13921 aggatagagt ttttatatga tagagaccat gttattggac aagcttatct acttgctgta
    13981 gaaaatatta atgatatagt agtagtattt agaagtaaaa taataccact tcttcaagag
    14041 tatttttatt atgattcaga aaaagtaggt ttgattttag gaggaattgg aagaaatgaa
    14101 aaagataaat acattgttta taaagaaaaa cttatagctt ctgagttatt taaaaataat
    14161 aatgcctcaa taatggagag taaagttaac tattgtataa aacaaaacat atctagtgag
    14221 gagctaaaaa atatatatga gtaaaaatat atatgttaag gaaacctatg aatggataag
    14281 gataggtaat ggtgaaaatg agcttacaga aattgaatat gaaaaattgc ttaagtatct
    14341 agagaacaat aatgatgtat taaaaagtaa tataatagat attaaataca aaaaacttag
    14401 atttataaac tatgtaggca tcatatgttt tgaaaatgta atacttgaaa tacttcctaa
    14461 attgtcatta agtgataatc ttgtaaaaga tagagagata ctattacaga tgctttctat
    14521 atgtaataaa attccaatta caatgaatga aaaaataaga ttgagtttga aaaattataa
    14581 tctcttaaat ttttttgtta tgtatttcat tgagagtatg caaacacaga tgaaaaaagg
    14641 tatttatttt gaatatataa ataaaataga gaacttaaat gttatgaggg gtaaaatatt
    14701 attaagtaca tatgcaaaag aaaaaggcat ttctccaatg aaaataagat gtgaatatga
    14761 tgagtatagt gaaaataatt tcttgaatca agttcttaaa aaagcatgta tatctatttt
    14821 atgtagaata aatgacaatt caattcaagg caagattaaa aaaattttaa gctattttca
    14881 aaatgtagat ttaatttata tagatagaaa aaaactgttg gattataaat tttataaaaa
    14941 caatgataga tttaaagatt gttatttact agctagactt ctacttttaa atttgtctat
    15001 ggataatagt caaaataatc aagaggcatt ttctatatta tttgaaataa atactttgta
    15061 tgaagaatat ataggaattt taatcaaaag tatatgggac aattcattta gagaaacata
    15121 tatacaagat aagagtaaat ttcttttgaa aaatgaacaa actggtaaga aaaactttaa
    15181 tttaagaccg gatatagttt tatatgactt aaaaaatgaa tatgaaatta taattgacac
    15241 taaatggaaa gctattgaag tagattcaaa tgttttttat aggtcaagtg atatatacca
    15301 gatgtatgca tatataacag catatgaaaa tgcaaaaaga tgtatattat tatatccttg
    15361 tattcaaaaa gataagaatt atagttcctg gaaattatca gaatcattta agggtaagtt
    15421 tatagaagca aaaactgtga ggttagatga tataaaaaac acaaaaaatg atttaaaaaa
    15481 gataattttt aattataaat tttaaaaata agaattttaa aatttataaa agtaatttta
    15541 tataggtata aaaattacga gtagtataaa aaatttaata agaacttaaa ttaaaaattt
    15601 taaaaattat ttccatataa aatatggcat tgtaattgct tatttaatag aggatttttg
    15661 ta
//
LOCUS       DAMJWC010000087        15661 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMJWC010000087 DAMJWC010000000
VERSION     DAMJWC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15661
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.089"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            50..868
                     /gene="larE"
                     /locus_tag="PC503_003176"
     CDS             50..868
                     /gene="larE"
                     /locus_tag="PC503_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF2529136.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            923..2071
                     /locus_tag="PC503_003177"
     CDS             923..2071
                     /locus_tag="PC503_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF2529137.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2207..3595
                     /locus_tag="PC503_003178"
     CDS             2207..3595
                     /locus_tag="PC503_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2529138.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3624..4322
                     /locus_tag="PC503_003179"
     CDS             3624..4322
                     /locus_tag="PC503_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529139.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4325..5758
                     /locus_tag="PC503_003180"
     CDS             4325..5758
                     /locus_tag="PC503_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529140.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5780..6517
                     /gene="truA"
                     /locus_tag="PC503_003181"
     CDS             5780..6517
                     /gene="truA"
                     /locus_tag="PC503_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2529141.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHSPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6628..6835
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7088..8287
                     /locus_tag="PC503_003182"
     CDS             7088..8287
                     /locus_tag="PC503_003182"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF2529142.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8534..9580
                     /locus_tag="PC503_003183"
     CDS             8534..9580
                     /locus_tag="PC503_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HDF2529143.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTGQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9688..10851
                     /locus_tag="PC503_003184"
     CDS             9688..10851
                     /locus_tag="PC503_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2529144.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     NRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(10940..11320)
                     /locus_tag="PC503_003185"
     CDS             complement(10940..11320)
                     /locus_tag="PC503_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF2529145.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11323..11982)
                     /locus_tag="PC503_003186"
     CDS             complement(11323..11982)
                     /locus_tag="PC503_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF2529146.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(12088..13062)
                     /locus_tag="PC503_003187"
     CDS             complement(12088..13062)
                     /locus_tag="PC503_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2529147.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13102..13449)
                     /locus_tag="PC503_003188"
     CDS             complement(13102..13449)
                     /locus_tag="PC503_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529148.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13667..14623)
                     /locus_tag="PC503_003189"
     CDS             complement(13667..14623)
                     /locus_tag="PC503_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF2529149.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            15068..15436
                     /locus_tag="PC503_003190"
     CDS             15068..15436
                     /locus_tag="PC503_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF2529150.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         6165 a         1666 c         2546 g         5284 t
ORIGIN      
        1 agaatgtaaa aaaataatat atagttttat agttcatatt tttccagata tggaggtaaa
       61 ttttgtgaag gaaaaagaaa aattagataa attaaaaaaa atgttacttg aattaggcag
      121 tgttgtagtt gcttattctg gtggagtaga tagtaatttt ttgcttaagg tcgcaaaaga
      181 tacattaggt gaaaatgtta tagctgtgac tattcatgca atgatgcatt caagtaggga
      241 aattgaagag gctaaacaat atactcaaaa ttttggtgtt aaacatatca tattaaatat
      301 agaaaacttt gatttaaaag aatttaaaga aaatggtgtt gatagatgtt atcattgtaa
      361 aaaatatata ttctctaaaa taaaagaggt agcaaaagaa cataatataa agtacatagt
      421 agatggaaca aatatagatg atttaggaga ctatagacct gggcttaagg cattgagtga
      481 attaggagta attagtccat taaaagatag tagtttaaaa aaagaagaaa ttaggtcgct
      541 ttcaaaaaca ttaggattaa atacttttaa taaaccatca tttgcatgtc ttgcgagtag
      601 gataccttat ggagttgaaa taacagatga aaatttaaga atagtagaaa agagtgaaga
      661 atatctatcc aatttaggtt tttctcaatt tagagtgaga atgcatggag atatagctag
      721 aatagaagtt ggacaggaag aactaggtaa attttttgaa aataacaatt ttaataaagt
      781 tgatactaaa ttaaaaatat ttggctttaa atatgttaca ctagatatgt caggatataa
      841 aatgggaagt atgaatttaa atgtgtagat tattttaaaa ataaataagt tttatagtta
      901 atataaggaa acaggaggtt ttatgaaaaa ttatacgtta atatcgccat gtttttttgg
      961 aatggaaaaa atgctggcta gagagattac taatttagga tatgaaataa taaaaacaga
     1021 agatggaaga ataacatata aaactgatga gtttggaata gcaaagtcaa acatgtggtt
     1081 gagatgtgct gaaagagtac atcttaaaat tgctgaattt gaggcaaaaa gctttgatga
     1141 attatttgaa aatacaaaaa gaataaactg gtctagatat ataccttatg gagctcaatt
     1201 tcctatatca aaagcttcct ctataaaatc aaaattatac agtacaccag atgtacaagc
     1261 catagtaaaa aaggctatag tagaaagctt aaagaaaagt tatttggagg atggtttgct
     1321 taaagaagat aaggagaaat accctatttt tgtatttata cacaaagata aagtaaccat
     1381 ttctatagat acaacaggag atgctttgca taagagagga tatagagaaa aggcaaataa
     1441 agctccaata agagagactt tagctgctgg gcttatttat ttaactccct ggaaagcagg
     1501 tagagtttta gtagacccta tgtgtggttc tggtactata ttgattgaag ctgctatgat
     1561 tggtataaat atggcacctg gcttaaatag agagtttata tcagaaaagt ggagaactct
     1621 tgataagaaa atatggtggg atgtaagaaa agatgctttt aataagatag ataatgaatc
     1681 taaatttaag atttatggat atgatataga tgaagaatct atagatatag ctagagaaaa
     1741 tgctgaaata gcaggtgtag atgaatatat agagtttaat gtaggagatg caactcaatt
     1801 taaaagtgaa gatgagtttg gatttataat cactaatcct ccttatggag aaagattaga
     1861 agataaagac agtgttaaac agttgtataa ggagcttggt tatgcattta gaaaattaaa
     1921 aaattggtcg tattatttga taacttctta tgaagacttt gaatatgagt ttgggcaaaa
     1981 agcagataaa aaaagaaaat tgtataatgg tatgttaaaa actaactttt tccaatatcc
     2041 gggtcctaag cctcctagaa ataataaata agttttacat gatttatttg taaaatataa
     2101 aattttatta aaataagtaa aacattatga tgccttgaaa cgtctaatta ttgtgaggag
     2161 atttttgtga acaaatttaa agatttatag gattaggagg agttaaatga aagtgttaaa
     2221 gcttattact gtagtagccc tgatgatgtt atttgttact ggatgtaata taaaaactga
     2281 atctccagaa caattagcga agatacctga ctatgatgat acaaaaaaag tattgtatga
     2341 tggtattgac cagttactaa aaccagattc atctatgata ttgccttcta atacaaaaga
     2401 agtaggaaaa ataaataagg tagatttaaa cagcgatgga attgatgaat tagtagtatt
     2461 tgaacaaaaa gaagatttaa gtaataatgt gagtcaggta gggtttgtaa ccttgagtta
     2521 caatggagaa aaatacgtac ttggagacca ttttttagaa aatggcgaat caatagaata
     2581 tgctaatttt tatgatttgg actcagatgg atataaggaa gttatcttat tggttaaatc
     2641 caaagacaaa acgaatatgc atatatataa agtagtagat aatgaaataa caaaaatata
     2701 tgacttggat gcatcatggc ttcaaaataa agaagatttt aatgatatga aagtaaaaat
     2761 tggatatata gatggagatg acaagttaga catattgatg cttcatttga ataataagac
     2821 taatgaaatg tttgcaagtg ttgcaaattt tgatgggaaa atgaaaatca aagattctgt
     2881 taagtttgaa aatgtaaaaa acttaagtga attatatata acattaggta atgttgcttc
     2941 atctgttgga aattcttctg cagctataaa aggtattgta cttgatattc ctatattgaa
     3001 agataataac tatattacgc agatacttta tatgaaagat gggaaaatta acaaagcttt
     3061 tagtgattat gataaaacta ttactaaatc ttattatata cctgtagatg atattgacaa
     3121 agataagatt atagaaatac ctatagttgc aggcagtaca ggtaataata aaaatactta
     3181 tagttctaaa tcatctgcaa ctataagttg gtatagatgg aatggaaaag aaggtgctga
     3241 ctcaagttta atatttacaa gtcagatata ttataattat aaatataatt ttaaattatt
     3301 tattccaaat aatttatttg ataaaatact tgttgaacag gaatttgttg gagaaaaagc
     3361 agtatttaaa ttttactatt ttgactattc agaccgtaag aatttattta atatagtagt
     3421 agagagtaaa aataaacttg aagatagaaa aaatacaggt actcaaaatt ctattgtact
     3481 tcaagagagc gatgaatata ctttcttact agttgtaaac aatgcaaatg aaatggataa
     3541 gctagatatg actatagacg cattaaaaga atatttctca ttaatatatg gttaatatta
     3601 tactcaattg gaggttttat tttatgaagg aaaagatact tatactagaa gatgaaattg
     3661 gtattagaag ttttgttagt ataaacttaa aaagggaagg ctatgaaata gttgaggcag
     3721 gtactggaag agaagctata gaaaaaatga caacagaaaa ggatattaca atagctcttt
     3781 tagatgtaat gcttccagat ataagtggta tagaagtatg taaatttata agggagaatt
     3841 ttgaccaagt aggtataata atgcttactg ctaaagctca agaagatgat aaaatagaag
     3901 gatttatctc aggagcagat gattacatca taaaaccatt tagtataaaa gagcttttag
     3961 tcagagtttc tgctcttctt agaagagtag caaaggatga ttcaagtgtt aagtcgagtg
     4021 agatagtttc tccaccattt atacttgata tagacaaaag aaaattattt aaaaatggaa
     4081 aggaaattga gcttacacca actgaatttt caatagtgaa atatctaata tcaaatgcta
     4141 agcagtcgtt aagtagagac cagatattag acgaagtatg gggaactaac tatttatatg
     4201 attttaaaat agtagatgta aatataagaa ggataagaaa taaaatagaa gatgacccat
     4261 caaaaccaaa atatatacaa actatttggg gttatggata ctgttttaga aaggaagaat
     4321 aatagtgtta cattttgaag gtctgagaaa aaaagtaata aaaaactatt ttataataat
     4381 tattataatg gttactctgt ttgaaggatt gttcatgttt tacatacaaa actactatta
     4441 tgattctgtc aaacagctac ttgaatctga aataaaatat gctgatgaat ataatgctat
     4501 tacaatggaa actacaagtt ttgagaaaaa agtaaaaaat atatttgata aacaaccctt
     4561 aactaaaaat tcagaatttg gaatttcaat aatagataaa gataaaaata ttatattaga
     4621 ccaatatggt tttaaaagta aagaaaaagc aaactatgaa gatgttaaca atgcattaaa
     4681 agatataaaa actaaaaatt taacacctta tacttataga ataccagata caggggagca
     4741 tgttatgagt atctccttac cacttaaggt aaataatata atagaaggtg ttgttagata
     4801 tacagtatca ttagatgcta ttgataatgc aatattaaag caagctacat ggcttatatt
     4861 agcaggaata tttatactta ttatagctat actaataagt cttaaatttg ctgagactct
     4921 tataaaacca ttacgagagc taaagaaatt tgcaaatgaa ttggctgtag gaaattataa
     4981 tataaaatta gaaaagatga agattgtaga tgatgaaatt ggtgatttag cacagacatt
     5041 tgaacacatg gcacatgaga ttgacaaaag tgaaaaatta aaagaggaat ttatatcatc
     5101 tgtatctcat gaactaagga ctcctcttac atctataaag gggtggagtg aaaccttagg
     5161 ttatgaaagt ataacaagag aagaactaga cttaggttta ggcattatac aagatgaaac
     5221 agaaagactt ataaaactag ttgaagaatt attagacttt tcaaggcttt cttcagacag
     5281 gataaaactt catgttgata tagttgatgt tgaaggttta attgtaggtg ttgtaaatca
     5341 acttaaagtt aaagcagctg aaaaagatat atcactttta tttgaatttg aaaatgaatt
     5401 tatagagaac attcaaggag ataaaaatag attaagacag gttctcataa atttaataca
     5461 aaattcattt aaatttacga gtcaaggtgg ttacataaaa gttgtagctt ctcaagatga
     5521 agagataaca accatatcag tagaggataa tggttcaggt atagaaaagc aaaatttaaa
     5581 taaagtgtta gataaatttt tccaagaaga ttataataag gctggtagtg gattaggact
     5641 agcaattagt aatgaaattg taaaacttca tggtggaaga atgaaaatag aaagtgaaaa
     5701 gaatgttgga acaaaaataa cttttaatat aaaaaataaa tttgctaaac aagcataaat
     5761 tcttagaaag aggattaaga tgagaaacat aaaaatgata gtagcatacg atggttcaag
     5821 atataaagga tatcaaaaat taggtgacaa taatatgact attcaagaaa aacttgaaaa
     5881 tgttttaagt aaaatgacta atgaaacagt ggagataata ggttctggaa gaactgatat
     5941 gggagctcat gcaagaggac aagtggtaaa ttttagaact aattgtatgg attctttgga
     6001 taaaattcaa aaatatttat atgaatattt accagaagat atagttgtaa aaactgttga
     6061 agaagttgat gaaagatttc attcaagata caatgtaaaa tcaaaaactt atatgtataa
     6121 aattgacaat aataagtatc atagtccttt tataagaaaa tatgctactc atgtaagtaa
     6181 aaaattagat ttagatagaa tgagaaaagc aagtgagtat ttagtaggag aacatgattt
     6241 taccagtttt gcttcttcta aatctaagaa aaaatcaaat gtaagagaaa tttattctat
     6301 aaatataaaa gaagatgata atgttataga aatatatgta gaaggaaatg gatttttgta
     6361 taacatggta aggataatag taggtgcttt aatagatgtt ggtctaaaaa gaagagctcc
     6421 acaagatatt aagtatatgc ttgaatcaaa agatagatgt caatcatcag atactgcacc
     6481 agctaaagga ctatgtcttt ggaaagtaac atattaatca attatataaa actctcttta
     6541 aaataaaaat aaaataaatt atatagttga cataaatgga aaaataaact attatatatt
     6601 ttataagaga gatataaaac tttatattta aatcctgtga gaaagagagt aacttctatg
     6661 tgttttatag agagctgagg atggtggaag cttggcaaat aagtattagt gaaaagaact
     6721 ttggaggata ctaattgaat ttagtatgtt agtaggtaat ctcgccttaa gagaaagagt
     6781 ggataagttt atcttatcaa ttagagtggt aacgcggata tatttcgtct cttggttttt
     6841 ccaagaggcg ttttttaata tatttaatta ttagtgttta tctggtatgt tgaacattta
     6901 ctaattgatt agctaagttt atcaataaga gtggtaccgc ggatatttcg cctcttagta
     6961 ttttaaaata ctaaggggtt tttttagtat taaaatgatt ttatgtgagt ctaaattctc
     7021 agagtcattc aatattaaga atttctataa aataaaaatt ataatttaag attgggagga
     7081 attaaaaatg aaggaaaaag tagtattagc atattcagga ggacttgaca catcaatcat
     7141 aataccttgg ttaaaggaaa attatgaaga tatagatgtt atagctgttt gtggaaatgt
     7201 aggtcaggaa gataaaatgg aagatgtata tgaaaaagct ttacaaagtg gagcatcaaa
     7261 ggcatatgtg gatgatataa gtgaagaatt tgtaactgaa actatattta aagccgtaaa
     7321 agcagaggct aaatatgaag gaaaatactt attaggaact tctttagcaa gacctataat
     7381 agctaaaaaa ttagttgaag ttgctcataa agaaggtgca aaatatatat gccatggatg
     7441 tacaggaaaa ggtaatgacc aagttagatt tgaagctaca attgcagctc ttgacccgac
     7501 tataaaagtt attgcacctt ggagaatttg ggatataaaa tcaagagaag atgctataga
     7561 ctatgctgaa aaacataata taaaggtaac agcaactaaa gctaaaatat attcagtaga
     7621 tgctaacctt tggcatgttt caacagaagg tggagatata gagcacctag aaaatgaaca
     7681 taaaaaagat gtttataaac aatgtgtaga cccagaagat gcatgtgatg tagctgaata
     7741 tgtagaagtt tactttgaaa aaggtgtacc taaaaaggta aatggtgaag aattatctcc
     7801 agttgcactg attcataagt taaatgagtt gggttgtaaa catggaattg gtgttataga
     7861 tatagttgag aatagacttg ttggtatgaa atcaagaggt atatatgaga ctccaggagg
     7921 aacaatcctt tatgaagcac ataatatttt agaaagtgct actttagaca aagatacatt
     7981 acatttcaaa caaatggtat cttataaata cggagaactt atttacaatg gactatggta
     8041 ttgtaaatta agagaatcta tagatgcatt tatggaacaa actcaagata atgttacagg
     8101 aacagtaaaa gttaaacttt acaaaggaaa tataaaacct gctggaatat ttactgaaaa
     8161 tgctctttat gatgaaggaa tatcttcttt tggaaatagt gaactttatg accacaaaga
     8221 tgcagaagga tttattaatt tattcacttt accattaaaa atcagagcta tgaaagctgg
     8281 aaaataataa aataaattat ttaagagtgt ataaaaacta tttttaggtt tttatatgct
     8341 ctttttttat ttgaatttat taacttatac agtaaatagt ataaaaaaat atattatagt
     8401 tccaaatggc ttaataatgt gaaaatataa gacctaaaat ataaatttta taaatacaat
     8461 agttattgac tctctcattg taagagggtt tatactgaat ctaatgaaaa tttatagtga
     8521 ggagatagat tatatgagaa aaataattga aattaaacat cattcacatg attatgagtg
     8581 tatgtggaat ggtatagaag atttatatat aaataaaacc ggtgaatgcc ttccaaacga
     8641 ttttttcttt ttactgtcag gttttggttc attttgttat atgaaaacaa ataaagctga
     8701 tttgaaaaga atggtagctt tgggagatgg aaggacaaaa cagatgtata aatttttagc
     8761 accaattgtt ggatttgaat acaaacatca tgagtttaaa aagtatgagc aagcattaaa
     8821 gaaagcaaaa tctgaaattg atgatggata tccagttatt ttaggagctt tagatatgta
     8881 ttatctacca tattataaga agctatatca taaagaacat attccttttc attatatatt
     8941 aatggtagga tatgatgatg aaggaatata tctgtatgat tgtggtagaa cagaattatt
     9001 acatctttct tatgataaat tacgtgaaag catgaattgc aattcccctg gattaagcaa
     9061 agaaaatact atttgcacaa taagaatgaa tacttcaaag aataaatata acattgctag
     9121 agaagctatt gctataaagc gtgatatgtt tttaaatcca cctaaaggat ttttgggata
     9181 taaaggtttt gaaaagttta ttaaagagtt gccacagtgg aacactgaat tggataaaga
     9241 tgattatgat aagattttga ccaatatggt tatgtttttt ggaacagtac caacaattcc
     9301 aaatgcaatc aaaggaatta aagaaccaga tactgttcaa tttaaaggtg gatttgataa
     9361 aatgagtaga atgctcaaca gtattgggga ggaatacaaa aacgactctt ttatacaagt
     9421 agctgatatt tttgataaaa ctgctattat aattgagaaa atatccaata ttataataga
     9481 ttacttaact caaacatgtg atgatacagg acaacttccg ttattgttct ctgaggtctt
     9541 agagcatatg aaaacaggat atttaatctt ggatgtataa aaaatatatt gttgacccta
     9601 acattacgta atagtgtaat atgaaaatat agcttgaata tattagtagg tattgatggc
     9661 tgtaaaatta aaatttgagg tgtggatatg agaacagtga aacaagtttc tgatttaact
     9721 ggaataagtg tgagggcatt acattattat gatgaaatag gtcttttaaa accaaataaa
     9781 attacagatg caggatatag actttatgat gatgaatcta ttaaaactct tcaacaaatt
     9841 ttatttttta aggagattga tattccttta agagaggtta aggaaataat gtcaagccaa
     9901 tattttgata aggttgaagc tctaaaaaat caaaaaaaat tacttatttt aaaacgaaag
     9961 agactggatg aattgataga gcttataaat caaactctaa gaggagaagg aaatattgat
    10021 tttaaagagt ttgatatgag cgagtatttt gatgttttag aagaatttaa aagagagcat
    10081 aggaataagg taattaaaat ttatggtagt gtagaaaaat acaatgaata tatagaaaga
    10141 gttaagtcta atgaagagaa aattgctaaa atggctataa aacaatatgg aactattgag
    10201 aagtttgcta aagctataaa aacaaatttt agcagtgata tattgaattt aggagaaaaa
    10261 tttgatagat ataaaaatga ttgtttaaaa gaaaaacatc caaaattaaa agaattatat
    10321 agaaagcttg tagaagattt aaataggaat ccttcttcaa cagaccttca agaaatagca
    10381 aaagagataa cagatatatc taaaaaagat tatgaaattt tctctatgga tactggtgat
    10441 gacaactggt attatatggt tcaaaattat ctagtaaatc ctatgtggat agaagaagta
    10501 gataaaaagt atggaagtgg agcaggtaag tttattggac aagtactaaa gacttatcta
    10561 agagatagaa aaccaaagat aaatacattg tatgaaaaac ttgtagaaga tttgagtaga
    10621 gattgttctt caagggaagt tcaaagcatt gttgaagaaa tagacaatga aatgaaaaga
    10681 agtaatgaat tttataaaat agacaatggt gaaagatact ttgattatat gtcagagctt
    10741 tatttacaag attctaacta tataaaagta actgataaga attatggtga tggtgcatct
    10801 aagtttattg gagaagcttt taagatttat tttgataata ataattgttg aaaatttgga
    10861 agtaaaaaat atgcaagttt tataaaagca caaaaataag gatgtagatt agctccatct
    10921 atatccttat ttaaagttat taaaatatat agtttacatc aaacttaaca ctttcaataa
    10981 tatttcccaa atatgttttt atactttcaa cttcttctaa agattttaat ttattttcag
    11041 tataaattgc tttgtccaga atattaaacc ttaatcctat ttcatcaaag tactcatgat
    11101 ttaaaacttt gtaccaatgg tttttttctt tattccaact cgtagatatt gaatcagctt
    11161 ctttttgagc tttttcccaa tcttcatttt ctatagattt ttctaaaaca gatatattgt
    11221 ctttatatcc ttctgtaaaa tcatatagtt tattgttaac ataaaatcca aataatacaa
    11281 ataagatagt ccatagtata acaaatgttg tagatttcaa tattaatcac cctttttatt
    11341 ttgaataaat attttgtcat tttcatctaa aacacaaata agaacatctt taaaagtttc
    11401 tatgtgatta gattttaaaa tacccattaa ccagttagta tctttttgag ctatgtctag
    11461 atttttattt attattctac catccagtat aagtgggata ggtaaatgat taaaagctct
    11521 tggaggagta ctattgtagc ttgatgctgg tacaacactt agattaccat cagtctccaa
    11581 aatagcatat tgtacatctt ttaggttaaa gtatccttga atcctaagtt gttctaataa
    11641 ttcatctata ctaattcttt cttttttaag ctctttatat acaatttttc ctttatctat
    11701 taatacagaa ggtttacctg ataaaaatga acttaatttt ctacttttta atgataagaa
    11761 tgaaattaga gtctgcatga ttacaagtcc agatattgct gcaacaccat ttatgattgg
    11821 tatattatta ttttccattg ggacagatgc aacttctgca attaatagtg ttataactaa
    11881 atcaaaacag ttcatttcag ctatttcacc ttttcccatg actctaagtg caattagcac
    11941 tgttatgtat aatataatac ttcttattaa tactactgtc atatctatca attactcctt
    12001 taaaaaatat ttacacttag ttagtatatc ctatataaaa aatttaattc aaagtataaa
    12061 aaaccttaaa taattggatt caactattta aggttttttt gataatttta atattaaatt
    12121 ttttatggat tttctgttac ttttatttat tttaataaca gattcaacaa aactcttttt
    12181 atctcctaat tttaagataa aatcaggata ttcttcaaat tcattgagtt ttattaattt
    12241 gaaagaagaa gatagatttt taaagttaat aattttagag ttattcacta atacacttct
    12301 ttttttaaaa taaatttctt ttttacttat atttagtata gttaatattt gtttaagata
    12361 tattattata tcttctggag ttctatcaaa tttgagttca aaattttcat cttcaaagta
    12421 gggaatataa tataaaggtg ttttgagagc aggtaattta ttatataatt cttcaagaat
    12481 atcgatattt ttaggggagt taaagaaaaa gcatttacat acattcatta aatccacagc
    12541 atctgaaagt gagttatgtt taatatctcc ttctacagaa aaaatttttt tcatattcag
    12601 taaagatatt tgcttagata agattctatt attgtatgta atatgttgag atataaaagg
    12661 ttgaatgtca atcatcatat taaataactc taagcattta cctgtatatt tatatactct
    12721 aaatgaagtt agaaggccag ttatatcaaa atcaccccaa ttatatattg taacatcatc
    12781 aaatttacaa aaccatttat aaaaatcatc cataacatat aaaagattag gagcattatt
    12841 gatatctagt tggttcaatt tggttaaatt tttacattta tttgaaagta ttttattgta
    12901 ttttggctta actaaagagt aataattatc tattgtatta aattcgttat caactaaaac
    12961 tccaccaata gaaattaatt ccgcaccatt atattctttt ggtttatttt tattatcatc
    13021 tagtatatta aattcaaagt ctataaataa cttgtatttc ataaatctaa agcacatcct
    13081 caggtaaatt atttattgag cctaagcatc ataagaatca atagatataa tgactctaaa
    13141 catcaaaggt tcattacaac ttttatttat ttcataattt aattcaaata aatcttttaa
    13201 gatataattt ataagtattc tttcccaacc catttttaaa ttaactttag agtctattaa
    13261 tatattttct atctttttaa atatttctat atttgctggt attatactga gctcaatatt
    13321 acttttaaac gggttagact gtaaatctgt tataagtata ttttttaatt cctctgtaag
    13381 ttcagaaatt aaactatcac ctatgtattt ttttatgatt tcctctctaa tttcttttaa
    13441 atttagcaat attagtacct gctacttaca tagtagcttt tcctttcctt ttaatactat
    13501 tattcatttt tgaatcttat ttagatatat tttaagatta aaagtcttta gctatataat
    13561 tttttaccca tttttaactt atattaacat attacaggct tatatctcca ccctgtttac
    13621 attgaggatg gagtatattg cctattttga taaaaatgat aggttgctat ttgcctattc
    13681 ctttttctga taatttttct aacatatctt tggtcatttt atctaaatca taactaaact
    13741 taaagttcca ttcttttact gcactactac tgtctagaga gttaggccaa gaatcagcta
    13801 tactttgtct tacagggtct acatcatatt ctatcacaaa atcaggaata tattttttta
    13861 tagaatcagc tatttcctca ggagaaaagc tcatagcagt aatattaaaa gcatttctat
    13921 ggatgagttt atcagctgga gcttcgatta aatccactat tgattgaagt gcatcaggca
    13981 tatacatcat atccattttt gtaccttctg ctatgtaaga tttatatctc ttatttttta
    14041 atgcctcata atatatatca actgcataat ctgtagttcc tccaccagga ggcgtaacat
    14101 aagaaataag acctggaaat ctaacacctc tagtgtctac tccaaatttt gagtgataat
    14161 aatcacatag taattctcca gaaactttag tcacaccata catagtatta ggtctttgta
    14221 atgtatcttg aggagtcata ttttttggag aattttcacc aaaagcagca attgaactag
    14281 gtgtaaaaaa tttacaatcc aattctttgg ctatttcaag accatttatt aatccattca
    14341 tatttaagtt ccaagcttct agaggtttac tttcagcaac tgcagaaagt aaagatgcta
    14401 gatgaattat agtatctaca tcatattttt ttgcaatttc aaaaaaacga ttcttatctg
    14461 taacatctaa tatctcaaat ataccagatt cacatactgg attaccttct tttactctcc
    14521 ttgaactagc gattacattt tgttctccat actcatttct aagctttatt gttaattctg
    14581 aacctatttg tcctaatgca cctgttataa gtattttttt caattttaca acctcctaag
    14641 ggtttaattt atgtagtact acttattttt attttagcaa atcttttgtt taaatacaaa
    14701 gaattaaaga taataatata cgacttaatt gaatgaagtg cagtaagtgc ctaaaaattt
    14761 aaagctaata tataatggta tattgtataa caataaaaga gtagattaaa ttattatata
    14821 tagattgtgt gactaagtca cagaaaatag agttaattta atatataata aaagcatatc
    14881 aagtaaagct ttaaattaaa gtaactttat aaataaaaag taatataaat tgataaaatt
    14941 ataaatttat ttatagtgaa tatgggttgg attttataga tacaaaaata gtatatatga
    15001 tatgtagacc attagcaggt ttaaagtagc aaaacatata aaataaaatt tgaaaggaag
    15061 tataaaaatg acaagaccat caatatatca tagccaagga tacacttgtg cagaggcatt
    15121 aataaagtct tataatgagg aacataacac agatatacca atctcaatag gaagtggtat
    15181 gggggttgga atgaatgttg gaagtgtttg tggagctgta aatgctgctg ttgttataat
    15241 agggtattta aatgggcgaa atagtaattt agatgaaaat atagcaagga agtattcaag
    15301 agagctattg aatagagtaa gaaataaata cagctcagaa atatgtgtat ctcttaaaaa
    15361 aaataaagta acttgtgaag aaataataaa tttcacatat gatgctctaa atgatatgct
    15421 aaaaaatcaa aaataattct aagaaacaag tattttacat tcgatagaat acttgttttt
    15481 ttatgatatt tttaataagt attagtttat tataattttt aaatcaattt tattatattt
    15541 taattgaaac aatctacttt gaaaattact aactgacaaa agaatatgat tatagtatag
    15601 aaaaaatgta aattatttaa tattaagtga gagtatatgt ttacctatat aaaatcgtat
    15661 a
//
LOCUS       DAMJWC010000088        15634 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMJWC010000088 DAMJWC010000000
VERSION     DAMJWC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15634
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.090"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(115..849)
                     /locus_tag="PC503_003191"
     CDS             complement(115..849)
                     /locus_tag="PC503_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2529151.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            974..1690
                     /locus_tag="PC503_003192"
     CDS             974..1690
                     /locus_tag="PC503_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2529152.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            1824..2516
                     /locus_tag="PC503_003193"
     CDS             1824..2516
                     /locus_tag="PC503_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529153.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            2506..3687
                     /locus_tag="PC503_003194"
     CDS             2506..3687
                     /locus_tag="PC503_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2529154.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            3969..4424
                     /locus_tag="PC503_003195"
     CDS             3969..4424
                     /locus_tag="PC503_003195"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF2529155.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            4414..5139
                     /locus_tag="PC503_003196"
     CDS             4414..5139
                     /locus_tag="PC503_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF2529156.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            5111..7492
                     /locus_tag="PC503_003197"
     CDS             5111..7492
                     /locus_tag="PC503_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF2529157.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(7697..8926)
                     /locus_tag="PC503_003198"
     CDS             complement(7697..8926)
                     /locus_tag="PC503_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2529158.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            9527..10441
                     /locus_tag="PC503_003199"
     CDS             9527..10441
                     /locus_tag="PC503_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529159.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            10465..11100
                     /locus_tag="PC503_003200"
     CDS             10465..11100
                     /locus_tag="PC503_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF2529160.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            11476..12192
                     /gene="pyrF"
                     /locus_tag="PC503_003201"
     CDS             11476..12192
                     /gene="pyrF"
                     /locus_tag="PC503_003201"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF2529161.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            12218..13261
                     /gene="carA"
                     /locus_tag="PC503_003202"
     CDS             12218..13261
                     /gene="carA"
                     /locus_tag="PC503_003202"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2529162.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            13314..>15634
                     /gene="carB"
                     /locus_tag="PC503_003203"
     CDS             13314..>15634
                     /gene="carB"
                     /locus_tag="PC503_003203"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2529163.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIM"
BASE COUNT         6300 a         1721 c         2816 g         4797 t
ORIGIN      
        1 aatatagatt aaagataata acatataata aataaaaaag taagattgtg tagattatat
       61 aaagattatt tacaattaat acaatcttgc ttttttattt aaaaatttta attattattt
      121 aaaatttttt atcttctctt tatcccatat aaacaatttc tcagaattat ttaaagcacc
      181 aaatacattt cttttaaaat caggcatctc tttatttaaa ttagcaataa gattttttat
      241 gtactctctc ctagtatgac catttgcagg gcagggattt gtgataatag gatagttaga
      301 atcttttgaa attttcttag tcatatactc ttctatgtaa accataggtc ttataactgt
      361 taaatcctgt ctgtctaggt atgtctttgg ggaaaaacaa tttactctac cctcataaaa
      421 catagacatt aaaaatgtct caattgcatc atctttatga tgaccaagag ctactttatt
      481 acatccaagt tttttagcat tatcgttcaa agcacctctt cttaaattag cacacaatgc
      541 acaaggattc ttttcttgtc ttatatcaaa tacaatttct tttatgtcag tttgaaattc
      601 ataaaaagga acatttattt ctttacacaa tttatctagt ggagaattat caacacctcc
      661 agtatttaat gttatggcta tcaattcaaa gttttgtgga gaaaatcttt gataactttt
      721 aagtatatga agtagagtta aactatcttt tccaccagaa agtccaaccg caattttatc
      781 attttcttgt atcatatcaa aatcttgtat agccttacga gctttactta gaagtttttg
      841 tatagacatt ttatcaccat cctttaaaaa tattaaattt aagatttatt taagatttac
      901 ttataaaata cttaagtctt atactctaaa attaacatta tagcaaacat aacaaaaagg
      961 agaagattta attatgaaaa aatttaaatt aataggagcc attattttag tagtatttat
     1021 aagtgtattt atatctaaag atagattact taagaaagat aaagatccaa tagtagctgc
     1081 tcaacatgat tcagaacaag atgttgaggc aaattctcaa aataaaaatc actcaaatag
     1141 tatatcaaat atattattgg taaacaagac aaatggaatt agcaaaaact atactcctga
     1201 aaatattact aaggtaaaca taccttttgt tgaagaagca acagaggaag aaaaacaaat
     1261 ggcaggagaa cctgcaaagg cagttgaaga tttagttaag caagctaatt cagaaggaat
     1321 acagttttta gggtcttcag catacagatc ttatgatact caactggata cttatacaag
     1381 aagggtaaaa tctcaggggc gagaaaaggc agatgcgtat gtagcaaagc ctggttacag
     1441 tgagcaccaa actggacttt gtattgattt aacaaatcca gaaagatggt ttgttggaag
     1501 tacaaaagaa gctaaatggt tggcagaaaa tgctcacaag tttggattta taataagata
     1561 tcctgaaggt aaagaagata taacaggtac agcatatgaa ccatggcata ttagatatgt
     1621 tggtaaggat gctgccgagg aaatttattc aaaaggatta actttagaag aatatttaca
     1681 aaataaataa tataaatgtg taaataattt gtattatatt ggaaatttag aaattaataa
     1741 atttatagat tacactaact aaaatatagt ataattttat atgaataaag ctatatacaa
     1801 agattaagtt aggatgtgta aaaatgaata atacagttct tgttgtggat gatgaaaagg
     1861 aaataagaga ccttatagag atatatcttt taaatagtgg atataatgta attaaagctg
     1921 aagatggaaa agaggctcta gatattttaa aaaaggaaaa tattcattta atgatattgg
     1981 atataatgat gcctaaaatg gatgggatag aagtttgtag aaaagttaga gaaagtttga
     2041 atataccaat acttatgtta agtgcaaaat cagaagacat ggataaaata caagggataa
     2101 tgactggtgc agatgattat ttgacaaaac catttaaccc acttgaactt actgtgagag
     2161 tgaagtcgct gattagaaga gcatattatt ttagtggtgc taataatgaa gataaagatg
     2221 tcataaaggt tggagtagta attatagata aggaaaaaca tagtgtaaca gtggctggaa
     2281 atgaaataat tttgacatca agagaatttg atatattata tttactagca aataataaag
     2341 gcagagtata tagtacagaa gaaatatttg aaaaggtatg gaaagagaaa tattaccaat
     2401 ctaataatac tgtaatggtt catatgagca gaataaggga taaaattgaa aaatatacag
     2461 atggagaaaa aataattcat actgtatggg gagtaggata taaaattgaa aaataaaagt
     2521 ttattaaatc atatgtttcg acccatatta gatcttataa taagctgtgc tttaacttca
     2581 atgcttattt taacaagtat gtatataata aaatcattat atgtcaatag tgatatgtct
     2641 gtagttaatc aacttgtata tcaagcaaga gatttcagaa gtcttatagg gtatgattta
     2701 ttttatccat ttttatttac aatcacatca ttagcaattt attccatgat atcgtacaag
     2761 agaaataagc aaattgtaga ttttataaga aagactaata gaaaaaatca aaaattagaa
     2821 atcattaaaa gtgctgtaaa tttaatggat gaaggtaact tagaaaaaag tatagatatt
     2881 gagtatgatt tagatatatt aaaggataaa gaaaaggatg atattgatga actagcacat
     2941 aaaatcaata atatagtcca tcaacttaga aatataacta ttgaagagag acaagctcag
     3001 cagacaaaaa cagatttaat aacaaatgtg tcacatgact taagaacacc tttgacatcc
     3061 ataatgggtt atttaggagt gatagaagaa ggtaagtata aagatgaagt tcagatgatg
     3121 tattatgttg atattgcata tgaaaaatcg aaaaatttaa atgttcttat aaatgatttg
     3181 tttgaattga ctaaaatgca aaataataca ataaaattaa acaaaataga aataaattta
     3241 gtagagttat taagtcaagt agtatctcaa tttgaaattt attttaaaca agaatttatg
     3301 gttagtagaa ttaattttaa tgaagaaaaa ttaattgtaa aagctgatcc aaataaattg
     3361 gtaagagcat ttgaaaatct tataactaat gctgtgaaat atggaaaaga tgggcattat
     3421 gtagatatag tcacagagaa aaaggaagat atggcggttg taaaagtgat aaattatggg
     3481 gaaccaattc cagtgttaga tttaccaaat atatttgata gattttatag agttgaaaaa
     3541 tcgagaaata gaaatgttgg aggttctgga ttgggtcttg cgattacaaa aaatattgta
     3601 aatttacatg atggagaaat tactgtttca agcgataaat atcaaactgt gtttgaagta
     3661 caactgccaa taatacaatc agcttagtta taaaataaaa gtacgattat gtgatataaa
     3721 tattataaca ataaagtgtt tacaaaaata aaaaagtaat atataattta agtcagttta
     3781 ataagatact tatcaagagt taggggagag agttagctca gtgatcctat accaaccttt
     3841 tatcaggtgg tcctgctaac aacgatgaga tgacttgaaa taatatactc ttcttatcaa
     3901 taatagatag gaagagtttt ttttagaatt aatgtaacaa attttaaagt ataatggagg
     3961 attaaataat ggaaaaagta gaaagtttta agctagacca tacaaaagta aaagctcctt
     4021 ttgtaagaaa gtgtagtgta cttgatggag taaagggaga taaagtaact aaatttgact
     4081 tgagattttt acagccaaat gtagaaagtt ttggaactgc tgctatgcac ggtttagagc
     4141 atcttttagc tacttattta agagatacat tagatggtgt aatagactta tctccaatgg
     4201 gatgtagaac aggattttat ttaatactat ggggagatgt agatgccaaa acagttaaga
     4261 ttggtttaga agaagcatta aaaaaagttc ttgaatcaga taaaatgcca gcagctacag
     4321 ctatagaatg tggaaactac agagacttat ctttatttgg ggcaaaggaa tatgcaaaag
     4381 atgttttaga taaaggattt tctttaaata tatatggaga ataatttaat tggaagagaa
     4441 gatataagca taaatcaaag tgaagtttta agatatttac aatatagagg tcaagagata
     4501 gataaagacc ttaaatatac tattgatgaa tgtgtagcta taactaaaaa taaaataaat
     4561 cctagatatt tatctaggat ttatcctatt aaaataaata aagataatgt tgtagaatta
     4621 gagggaacaa atttaacatt agagagtaaa gatgtatatg aacttttaaa agaatgtaat
     4681 gagtgtgtaa ttatggcagc tactataggg atagatatag aaaaagaaat aagacgacac
     4741 tcttattcaa atttaacaaa aggactaata attgattcat gtggaacaac agcaatagaa
     4801 gaagtgtgtg acattgttca aaataattta gaaaaggttt ttttaaagca agataaattt
     4861 ataactatgc gatatagccc aggatatgga gatttaccaa tagaaaaaaa tatagatata
     4921 ttaaacgttt tgaatgctca aaaacaaata ggtctaacaa ttacttctaa tggaattatg
     4981 ataccgagaa agtcagtagt ggctattata ggtatttcta atacaagaat aaataaatct
     5041 aagaaagaaa agtcgtgtga aaattgtaaa aactatagaa actgtacata tagaaaagga
     5101 gcgaactctt gtggaaataa gacaatatct gaaaaataat atattaatat ttgatggtgc
     5161 aatgggaaca atgcttcaac aaaaagggtt aaagttaggt gaaaatccag aagtatttgg
     5221 tcttcaaaat ccagataaac ttatagaaat acatacagca tacttagagg caggttcgaa
     5281 tgtaattctt acaaatactt ttggatgtaa tgaactaaaa ttagatagta agtatactgt
     5341 agaagaagtg attgacaatg ctgttttggt ggctagaaaa gctatagaaa atgtagataa
     5401 tactaaacca agatatgtag ctttagatat tggtcctata ggagaaatgc tagagcctat
     5461 gggtacttta agttttgata aagcatatga aatatttaaa agacaagtac tacaaggcgt
     5521 taaatctgga gttgatgtaa tagtaataga gactatgatg gatttatatg aagctaaagt
     5581 agctgtatta gcagcaaaag aaaactctga tttacctatt ttctgtacta tgacatttga
     5641 tgaaggtgga agaagtttta ctggatgtat gccagaatgt atggtggcta ctatagaagg
     5701 tctaggtgta gatgcaatag gagttaattg ttcattagga cctaaacaac ttttaccaat
     5761 agttgaaaaa atagcatcaa gagctacagt ccctgttatg gttcaagcaa atgcaggtct
     5821 tccaaatata gttgatggag aggctatata tgatgttgat gcaaaagaat tttttgaagg
     5881 ggttaaaaag ttcgttgaag ttggtgctac tataataggt ggatgttgtg gtacgaatcc
     5941 aagttttata aaagaaatat ctgagaatat aaattctgtt acaaagggat gtatcgagaa
     6001 aattgataaa tgtgtagtct gttcaccatc aaaatttgtg gaagtacaat cgcctacagt
     6061 tgttggagaa agattgaatc ccacaggtag aaaatctcta caagaagcat taaaaaatga
     6121 aaatgttgat tatgctataa atttaggttt agaacaagta aatgctggag cacaaatact
     6181 tggagtaaat gttggtcttc cagagattga tgaaaaaaaa ctaatgccaa aattaataag
     6241 agagattcaa gcagtagtag atacaccttt acaagttgat tcttccaatg tagaggcctt
     6301 agagcaagga cttagatatt ataatggtag aacaatagta aactctgtaa atggcaaaga
     6361 ggagtcttta gaaagtatat taccaatagt taaaaagtat ggttcatgtg tggttggact
     6421 tacacttgat gaaaagggga tacctaaaaa ggctgaagaa agatttgaaa tagcaaaaag
     6481 gatagttaat agagcagttt cttatgggat aaaaccaaaa gatatattta tagactgttt
     6541 atcattaact gtttcagcac aacaagaaga agcaatagaa actataaaag ctataacaat
     6601 ggtaaagaca ctaggagtaa aaactatatt aggtgtttca aatatttcat ttggtcttcc
     6661 aaataggaaa gcacttaatg cttcttttct aacattagct ttaggggcag ggcttgattt
     6721 agcaattata aatccaaatg aatatagtat gatggaagct atcaattctt ttaaaatatt
     6781 aaataacaca gataaaggat gtataaacta tataaatcaa tatagcaata taaataattc
     6841 aaaaaaatcg gattcatcta caaagattga taaagatttg cccttggata ttttagttga
     6901 aagaggatta aaagatgaag caaaaaatgt aacactgaat cttttaaaag agaaggatga
     6961 aaattatata ttagatgaga ttttaattcc tgctcttgat aaagtaggaa aaagatatga
     7021 tagtggagat atatttttac cacaattgat tcaatcagca gaaacggtaa aagtttcatt
     7081 aaatacaata aaggaaactt tattaagtaa aagtagcaat aatgtatcca aaggaaaaat
     7141 aatagttgct acagtaaaag gtgatatcca tgatattggg aaaaatatag taaaaataat
     7201 gctagaaaat tatggatatg aagttataga tttaggtaaa gatgtcccta ttgaagaagt
     7261 agtggaagtt gctaaaaaga gaaatataaa attagtagga ttaagtgcac ttatgactac
     7321 gactgttcaa agtatgaaag atacaattca ggcactgaga gataatgaga taaatgcaaa
     7381 ggtatttgta ggaggtgcag ttttgacaga agaatacgct gaagaaatgg gtgctgatta
     7441 ttattcaaag gatgcaaagt ctgctgttga aatagcaaag ttaaattttt agcatataaa
     7501 ttaaaataaa ggttttacta aataggatat tttatatata atataaatat aagttttaga
     7561 tacttatgtt taaaacaata ggaattaatc tataataatg agattaatta atataaaaaa
     7621 tatttatcat caacattaaa aagggctggg aagtctggta taacttccat cagccctttt
     7681 tagttaaaat catatgttaa aaagcccaat taccattttt aaaaatctgt atttgctttc
     7741 catcataagt ctcaccaata atatccatat cagcagaacc aatcataaaa tctacatgtg
     7801 ttaaactgtc atttacacca tgttcatcta attcttcatc ttttaaattg tttccacctt
     7861 ccagacaagt cttataagca gaaccaattg caaagtggca agaagcattt tcatcatata
     7921 gagtattata aaaaattata tccgtattgg atattggtga gttgtatgga acaagagcaa
     7981 cttctcctaa ataatgagag ccttcatccg tttcaataag tttttctagt gtatctagtc
     8041 ccttttcagc agagaaatct attattttac catctttaaa tgttaagaag aaattgtcaa
     8101 ttatgtttcc accataaaca agaggttttg tactataaac agttccattt actttaaact
     8161 tatgtggcat tccaaaaatc tcttcagttg gaatattcgg attaaaactt attccattag
     8221 ggtctttgga tgctccactt agccaaacat gaccctttgg caagtctaga gtcaaatcag
     8281 tttttgagga tttatatttt aaagttttaa agttattttt atttagaaag tccattttag
     8341 atttaagatt ttcattatgt tcttcccatg cttttatagg gtcctgacca tctactcttg
     8401 aacatttaaa tatagcatcc cacagttttt ctattgcttt atcttctgat aaatttggaa
     8461 acactttttt tgcccaatct tttgttggca cagagactat actccattta catttatcag
     8521 ttagagtgta agaacgccat tcttttaaag cttttccaga tgccttctga aaatttgcaa
     8581 ctctttcagg gtcaacatct tttaataaat ctggattttg ggcatagact gataaaaatg
     8641 ccccaccttc ttttgctata tctacatatt gttctgctgt ccatttgggg aactcatgaa
     8701 atgcttcatc tggagcatat aagtatttaa taagagtact ttcttcatca gaccactcta
     8761 tataaacatt tttagcacca catttatatg cttctttaag tgcatttctt gcaaaatcag
     8821 cacattctat tggtgacttt ataagtagaa tttgacctgg ctgtatgtta actccaactt
     8881 ttattgctaa ttcagcgtat ttttctaaat ttctatttaa attcatattt atcctcctat
     8941 atttttaata ttgaataact tataaagtat tataacatta cttatgtttt taatattgaa
     9001 caacttataa aatattataa ctttacttag attttgggtc atattcaaaa tatttatact
     9061 ttatagattg agaaataaaa aaaatatttt aattaaaaca aattatgagg ataacaaact
     9121 tatttaagta gtatgttttt tgttgataat aatattaaag tagaaataaa aatacttttt
     9181 tagtgaaaag ctatacaaga ataccgaaaa aaacttataa tataataatg agatagatat
     9241 ttataaatga aaaaaaattt ttctggcaaa gcttaattaa aaaggtaata gctagtgttg
     9301 ttatttaaat tagcatagaa aatcaaataa aaaaattatg ctaatgtata gacattgata
     9361 aggtagaatt taagcctttt gaatgctata ttaaactaga gtagatattc ttatgaattt
     9421 caaaataggg caggaggaaa aaggaaataa aactataaaa aatataaagt atttatataa
     9481 atttatagag tttatacgtc agaagatttc agttaggagg gcataaatgg agctttatga
     9541 agccattttt tatagaaaat ctgtaagaaa tttttccagt aaaaagataa aaaagccatt
     9601 gatggaagaa ataaaaagaa gttgtaaaaa tttagaatac ttaaatgaag atttaaatat
     9661 taaagcacat gttgttgata gaggtcatat aatacatttt ttgatgggga aggaatgtaa
     9721 agtaaaggca cctcattata tagtagttac atcagacaaa ggtgaggact atttacagaa
     9781 tataggattt gctacagaag gtgtagtttt gcgccttaca acattgggaa tagctacttg
     9841 ctggttggaa ggaaacttaa agagagaaga tatcttggaa tttgtagata ttgggaataa
     9901 gaattttgaa gaagatgagg aagatgattt agattatcta gctggaataa aaacagaaga
     9961 agatgatgaa aacaaaatag aaaatcctta tataataata gcatttggat atccagcaaa
    10021 aaatgaagag ttgtttagga cgagatatgc tagacctgat agaaagccag taaaagatat
    10081 gataaataag ataaatagga atagaaagtg gaaagatatc ttagaattga caagaagagc
    10141 tccatctgta aaaaattctc aaccgtggta tttccataag gatgaacgag gtcttcattt
    10201 atttgaaaag agacctaaga aacactgtga agatatgaat aaggttagct taggtgtagc
    10261 cttaagacat tttgatatag cttgtataaa aaataaaata gatgtttcat atgaaaaact
    10321 tcctataagg aataaaatag gaaaatcata ttttataact gtagtcgagc atgtgaaacc
    10381 agaagaagaa acccaagaag aaaatgtaac tctagaaaaa gaagaatcgc aagatgaata
    10441 aaattttgga aggggatatt ggatatgtat aagtgtggaa aatgtaatct tagaggctgt
    10501 tctaatggaa atatggataa attaatgaag atatgtccaa ctagagaaat tgaactacaa
    10561 caaaaagcaa agcaacttta tgaagaagaa gagaatagaa aaatagctta taatgctgga
    10621 ttagttgaag cagaggggta ttgtcaatat actagactaa aagagattat agagtttgct
    10681 aaaaagtgtg gttataaaaa gattggcata gcattttgta ttggactaaa aagagaaatg
    10741 caaacagtgc aaaaaatatt tgaacatcat gggtttgaag tattttctgt tatatgtaaa
    10801 aatggggcaa tgcctaagag tacaattgga ctagaagcat ctcaaacaat atcaaagtgt
    10861 tcagatgagg taatgtgcaa tccaatagga caagctttat ttttaaatga agctaaggtt
    10921 gaccttaatg taattcttgg attatgtgtt ggtcacgata ctttagccat gaaatatatg
    10981 gaagctccta taacaacttt agttgtcaaa gatagagtaa ctgggcataa tccagttgct
    11041 gcaatatata atgcagaatc atattttgag aaaaaattgt ttgataaaga tgaagaataa
    11101 ttcaaagact tattgacata aaaagcaatt agtggtttaa ttataaaaaa gataaaactt
    11161 taaattatcc tatagataca taaagttata taaataaaga aaaatattac agctaaattc
    11221 cttaaagtag tccagagaga ctaaagggtt atagataatg ttagtatata acctctagta
    11281 aatcttctag aggtttttga tgagtataaa ataaaaattt aaatataata aagtctttta
    11341 aactagtcca gagagactgg gaaagatatc tcatagctaa tgaatagagt tatgtataga
    11401 taaaatcctt atgcctcttt tggtgtgagg atttttttat gattatttag gctttattaa
    11461 aaaggagatg taaaaatgat aaatggtaaa gaaaaattga tagttgcaat tgatactgac
    11521 gaatttgata aagctaaaga actaatagac agattagaag atagtgtaga catatttaag
    11581 gtagggctag agcaatacgt tgccacaaaa ggtaaaacaa tagattatct taaagaaaaa
    11641 gggaaaaaaa tatttttaga ccttaaattc catgatatac caaatactat gaaaagtgca
    11701 gtgaaagctg cagtgagaga taatgtttgg ttaatgacaa tacatgtatc agatatggaa
    11761 ggaatgagac aatgtgcact aattgctagg gaagaagcag aaagattaaa tatagaaaag
    11821 ccattagtag ttggagtaac agttttaact tcattaagca accaagattt acaggacata
    11881 ggatgtaata tgacaacaga agagttagct ataaagagag ctaaactggc aaaagaatca
    11941 ggaatagatg gggttgtttg ttcagcgcaa gaagtagata aaatagtaga agcatgtgga
    12001 actgatttta taacagtttg cccaggaata agacctaaat cagcagaggt tggagaccaa
    12061 aaaagagttg taactccatc agatgcaata aaaaaaggtg ctcattattt agttgttgga
    12121 agacctataa caaaagcaga aaatccaaga gaatcagcta ttaatattgt aagagaaata
    12181 gaaaatgctt agataaaata tttgggaggt agcttacatg aaggggaaat taattttaga
    12241 agatggaaca gtatttgaag gaaaagcatt tggatatcta aaggaagcta ttggagaagt
    12301 tgtatttaat acttcaatgg ctgggtatgg agaactattg acagatgcaa cttattatgg
    12361 acaaatagtt actatgactt atccacttat aggaaactat ggaataaatt tagaagatgt
    12421 tgaatcaaat aaggtgcaag taaaaggact tattgtaaga gaaaaaagtg ataacccaaa
    12481 taattttaga tgtgaaatgg atatagacac atatctaaag caaaataagg taataggact
    12541 tgaaggaata gatacaagag cattaactaa aattattaga aacaatggaa cgaagagagg
    12601 aattataact ttagaaaatg tatcattaca agatgttcag tctaaattag aagagcattg
    12661 taacaaagat tcagtaaaaa atgttacaag aaaagaaatt gaaaatataa aaggtactgg
    12721 agctaaagtt gtagttatag actttggtgt taaaaatagt gtactagagt ctcttaaggc
    12781 ttgtaactgt gatataacta tagtaccagc aatgactaca gtagaagaaa ttttaaatat
    12841 aaatcctgac ttaatcttat tatctaatgg cccaggaaat ccagaggata taaatgatat
    12901 agttgaaaat ataaaaaaat taataggcaa aaagccattg acaggaatag gtttaggaca
    12961 tcaaatttta gcattggcat taggaggaaa gacttcaaag cttgtatttg gacatagagg
    13021 aggtaatcac ccagttaaat gtttagaaac tggaaaggta tttataactt ctcaaaatca
    13081 tggatataat gtttcagaaa tgccagaaaa tacagaagta actcacataa atttaaatga
    13141 caatactata gaaggaatga gacataagga attaccaata tatagtgttc aatacattcc
    13201 agaatacaca acaaaagaag atttagattg tatatttaat aaattcttag cattaatata
    13261 gatttagtat tatttacaga tagtaaaaac catttagata aggagaaaaa tttatgccta
    13321 aattagatag tataaagaaa actttagtat tagggtcagg accaataata ataggtcaag
    13381 ctgcagagtt tgactattca ggaacacaag cttgccagtc tttgaaagag gaaggaattg
    13441 aagttgtatt aataaatagt aatccagcca ctataatgac tgataaagaa gtggcagata
    13501 aaatatatat agaaccatta acaatagaat ttatagaaaa aataatagaa aaagaaagac
    13561 cagacagttt acttgcaggt atgggtggac aaacagggct aaacctagca gttgaacttt
    13621 atgaaaaagg catactagat aaatatggag taaagataat aggtacttca gtagaatcta
    13681 tcaaaaaagg tgaagataga gatatattta gagaagtaat gaaagaaata aatcagcctg
    13741 taatagttag tgatatagtt acagatttac aagcaggtct tgattatgca cttacaattg
    13801 gttatccagt agttgtaaga ccagcataca cactaggtgg aactggtggg ggtatagctg
    13861 ataatgagga agaattaaga gaaatacttt cacatggtct acaattaagt cctgttggac
    13921 aagtattaat tgaaaagagt ataaaaggtt ggaaagaaat agaatatgag gtaataagag
    13981 attcaaaggg aaattgtata gttgtatgta acatggaaaa tatagaccca gtcggagttc
    14041 atacaggaga cagtatagtt gttgctccaa ctcaaacttt aagtaacaaa gaatgtgcaa
    14101 tgcttaaaaa agcatcttta gatatattaa atgcagtaga agttcaaggt ggttgtaacg
    14161 ttcaatttgc acttaatcca catagttttg aatatgcagt tatagagata aatccaagag
    14221 ttagtaggtc atcagcttta gcatcaaaag ctacaggata tccaatagct aaagtttcgt
    14281 caaaaatagc tttaggttat actttagatg agatagaaaa tgcagtaact aaaaaaactt
    14341 atgcttgttt tgaaccaact atagattatg tggtggcaaa aataccaaaa tggccttttg
    14401 ataaatttaa aaaagcaaat agaaaattag gaactaagat gatggcaact ggtgaaatta
    14461 tgagtatagg aagtaacttt gaggctgcta ttcttaaagg gataagatca cttgaaacag
    14521 gaaaatattc attagttcac acaccatctg aggagagaag cattgaggaa ttaaagaaaa
    14581 gagttgtagt acctgatgat gagagactat ttgatttagc tgaaatgata agaagaggct
    14641 ataaagtaga aatgatagaa caaattacag gtatagataa atggtttata aataaattta
    14701 aatggatagt agagcaagaa gaaaaattaa aagttatgaa aattgaagat ttaactaaag
    14761 actatcttct tgaattaaag aaaaagggat tctctgataa aggtatatct gacctaatga
    14821 agataagtcc agaaaaatta tatgaattga gaagtctata caatataaaa ccagcatata
    14881 aaatggttga tacttgtgca ggtgagatag atgctatatc tccttactat tattcaactt
    14941 atgagcaata tgatgaggta gttgttagtg ataagaaaaa ggtgatagta ttaggttctg
    15001 gtccaataag aataggtcaa ggtatagaat ttgactattg ttcagttcac tgtgtaaaat
    15061 ctttaagaaa aatggacata gaaactataa tcataaacaa taaccctgaa actgtaagta
    15121 cagactttga tacatcagat aagctgtatt ttgaaccatt aacagaagaa gaagttttaa
    15181 gtataataga aaaagaaaag ccagaaggtg taatactaca gtttggtgga caaacagcta
    15241 taaaattggc taaattttta catgaaaaaa atatacctat attgggaact gattttgatg
    15301 atatagatgc agcagaagat agagaaaaat ttgatgattt actagagaga ctagatataa
    15361 atagaccaaa aggaaagggt gtatggtcac ttaacgaagg tattgaagtt gctaatgagt
    15421 taggttatcc agtattagtt agaccatctt atgtacttgg tggtcaaggt atggaaataa
    15481 cttataacga agaaaaatta tctcaatacc tacaagatgc atttgataga gaccataaaa
    15541 atccagtact tatagataaa tatctaactg gtagagaaat agaagtagat gctatatgtg
    15601 ataaggaaga tatattgata cctggtataa tgga
//
LOCUS       DAMJWC010000089        15089 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMJWC010000089 DAMJWC010000000
VERSION     DAMJWC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.092"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(264..644)
                     /locus_tag="PC503_003204"
     CDS             complement(264..644)
                     /locus_tag="PC503_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2529164.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            complement(845..2038)
                     /locus_tag="PC503_003205"
     CDS             complement(845..2038)
                     /locus_tag="PC503_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2529165.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            complement(2101..3357)
                     /locus_tag="PC503_003206"
     CDS             complement(2101..3357)
                     /locus_tag="PC503_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2529166.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNACSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            complement(4851..5585)
                     /locus_tag="PC503_003207"
     CDS             complement(4851..5585)
                     /locus_tag="PC503_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2529167.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            complement(6596..7234)
                     /locus_tag="PC503_003208"
     CDS             complement(6596..7234)
                     /locus_tag="PC503_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2529168.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFTLWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(7237..8094)
                     /locus_tag="PC503_003209"
     CDS             complement(7237..8094)
                     /locus_tag="PC503_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529169.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(8096..8470)
                     /locus_tag="PC503_003210"
     CDS             complement(8096..8470)
                     /locus_tag="PC503_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2529170.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            complement(9632..10822)
                     /locus_tag="PC503_003211"
     CDS             complement(9632..10822)
                     /locus_tag="PC503_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2529171.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(10838..12793)
                     /locus_tag="PC503_003212"
     CDS             complement(10838..12793)
                     /locus_tag="PC503_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2529172.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(12810..14876)
                     /locus_tag="PC503_003213"
     CDS             complement(12810..14876)
                     /locus_tag="PC503_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2529173.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGEIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYVDKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
BASE COUNT         5209 a         2658 c         1668 g         5554 t
ORIGIN      
        1 aacgaatatt atatatatca ttcataaaaa ctttatataa agaatagaaa caagttctag
       61 attactatag agatgacata tcaaaatatt tttaaaaagt aatttaagta ttagaagtaa
      121 ttgaagttag taaatataaa tgcgtttact tttaagtatt gcttaaggga ataaaaaata
      181 aaaataaact ctgcaaccat ctaaaaatag ttgcagagct tacaaaacca aaattatcta
      241 aattgtaata aaaataataa catttataca taagcttctt cccaatttac tacccagttt
      301 tctaacgact ttatcttttc ctctgttagc tcctcttcgt gaaatgatac taataaattc
      361 cttataaaat tattcttcaa aagattttgc acatttcttg atataaactc taaatatgcc
      421 ttttctttta ttgcaactgt ataatacata cacttgcctg tttcttgaac atataagaat
      481 cttttctttg atagttttga taaagttttt aaagctactt tttctggtaa attatgttct
      541 tctttcatat aatcaataat ctcatatgaa ttggttttta tatctaaatt ccaaataaat
      601 ttcataataa ctaactctaa ttttgataat ttttttaaac acatagttat cactccgctt
      661 ctttatctat ataattaaat attacaataa taatttcaca aaatcaattc taataatcat
      721 aacatacctt aaaatctgtt cttaacttct accttcttaa tctcccaaat gattttttta
      781 tattgtattc aatagtataa tccttttcca aaatataact taccagttaa aataatcttt
      841 atttttactt actctcgcct tttacagaag ttaataattt tttataagtt acatcaattc
      901 caaaagctcc aagaggtgca gttataagta tagctagaac tgctaacgtc aaaataagtt
      961 gtccagatgc catccccatt gcaagtggta cacctcctat tgctgcctgt actgtagcct
     1021 ttggaatata gccaatcata cagaacaacc tttcctttat tgtcaaattt gtcttaataa
     1081 ggcagaagaa tactcctacc atacggaata aaagaactcc aaatattaaa attacagctc
     1141 caattcctgc tttaaatgca taacttatat ctactgttgc ccctaccaaa acaaacaaga
     1201 gaatttcagc gccaacccat agttttgaat actttatgga caatcttctt gcaactacac
     1261 gatattttat ctgaaggaaa atcccaatac tcataactgc taataatcca gaaaatggca
     1321 caataccctc taaagcagtc tctaaactta tcattaaaaa tgagatactt aaaagcaaca
     1381 cccctttagc agaatctctc atatgaacct tcttaaaaaa tactgctaaa cagattccaa
     1441 tcactgctcc aactattaca cctaatataa ttgatactgg aatttgtaaa aaactaatag
     1501 ctgatatact atttccttgt gccaatcctg tgaatactgt aaacatcaca attacgaaaa
     1561 tatcgtctat agaagttcct gctaaaagca tctgtggaat acttttttct gtaccataac
     1621 cttcttccat taatttaagc attttaggta caataattgc gggagaaact gctcctacta
     1681 ctgcacccat gactgctgct tccaatatag aaacgcctag taattttggt gctaaaacta
     1741 tcattccgat aatttcaaaa gtagctggaa taaagcacat aagtacagca ggtcttccca
     1801 ctttcttcaa atcgtttata tctaaagata atccagccct tgttaatata ataatcaatg
     1861 caatctttct aaggtcagaa gaaatatcta gtattgaatt atcaatcaaa tttaaaacat
     1921 atggacctaa tataattcct gtaagtaaca ttcccaataa gttaggtaac tttatcctct
     1981 taaaaatacc tcccgaggcc attcctaata aaaaaatcaa agctaaactt gtcaacatat
     2041 tcctacccta tcctttctct aatattcttt ctcttctaat catacattat gttgttttat
     2101 ttattgtttt gttgaaattt tttgtagtga ataaatagat ttatccatat taaatatata
     2161 tgaaatagcg catactacaa agaaataagg taaatagctg tatccaaaaa cttctgcccc
     2221 tataaataca ggtgcaaaaa aagtatttgt agcactacca aagacactag catagccaag
     2281 cgctgcaact aattcaattg gcaaattaaa aaatcctgct aacaatacac caagactagc
     2341 tccaatggaa aacaaaggtg taacctctcc tccttgaaaa cctgctgaca aagtcagtat
     2401 tgtaagtata aactttaaca gccaatcaaa tgaataaatt tctccaccat agaaactatt
     2461 ttgaattaaa tttgtcccta aacctgaata tcttccttta taaaataaaa ggaataatac
     2521 actaagacat actccaataa tagcaattct tatcatagga ttttttaatc tattacctat
     2581 ttttcttttt gacaatttca gacaccatgc aaatgctcca ccaaccattc caaaaataat
     2641 tcctaaaaca ataagcttcc aaaatattga caagtcaaat acaactttag aagaaagtgc
     2701 aaaagaaaat ttctctaacc ctaaagcttt tgatactgaa cttgctgtaa aagaagcagt
     2761 aaacgcagga aaaagcgatt gatactccag tgaaccagct accaaaacct ccatagcaaa
     2821 tagtattgct gctattggtg tctcaaataa tcctgcaaaa ccagctgcca taccagttac
     2881 tagaaaaata ctacaagcat tttttatagg caacctttta cctacccaat gtgaaaaagt
     2941 tgcaccaatc tgaacagcaa ctccttctcg tcctgcacta ccaccaaata aatgggttaa
     3001 ccatgtacct gatattataa atggaaccaa tcttaaagga ataatttctt cttctccatg
     3061 ccctacctca aatattagat tcattccttt actacttttt cctccaaatt taaaatagca
     3121 ataagcaata acaactccta ctactgctaa aaatggtatc agatacattg gatatgtttc
     3181 tcgaatatct gtaactttta gaagaaccgt tccaaatatg gtgtctataa gacctataat
     3241 tgcaccaact ggtataccta tgagtcctaa aaaaaatagt ccaccatatg ttttataaac
     3301 gcttttaatt cttattatca ttttaatcca tattaaagtt ttaaattttt ctatcatttt
     3361 aattcctttc tatttgcatc ataagatttt ttgaaagttt tattacatca actgtagtca
     3421 atgtaatgac tatcataatt gttttttaaa ttgataggat ataggtacac tcttaaccca
     3481 ttcttaataa aataattaac atataatcta ctattttttc tattaattaa atatttcttc
     3541 aaatttaaaa aataaaaatt tagtaagtac ttcacctcca ttttattgat ttaaacaaca
     3601 aaaaaagctg gtggcatcta tgatatcata gaagtcatca gctcattggc agtttaggat
     3661 attatcatcc aagggagaac ctcattccca taattattat ataatttttt atttttcata
     3721 tgtctatttt atgtaaattg tatttttaat gttataaata atataaccta tcaattaaaa
     3781 tagtaaagcc tctaatatta tgagtgttca atatttcata ttatttttat gatatataat
     3841 ttaaatgatt ttctttactt tgcattatga tacataactt aaatattttt cctcactcca
     3901 cattatgata tattatttaa atatttttct tcactctgct tatattatga tacatgattt
     3961 aaatattttc ttcactctgc ttatattatg atacatgatt taaatatttt cttcactctg
     4021 cattatgata catgatttaa atatttttac tcactctaca ttatgatata ttatttaaat
     4081 atttttcttc actctgctta tattatgata cataatttaa acatttttct tcactttgca
     4141 ttatgataca tgatttaaat atttttactc actctacatt atgatatatt atttaaatat
     4201 ttttcttcac tctgcttata ttatgataca taatttaaac atttttcttc actttgcatt
     4261 atgatatatg gtttaaataa tcttctttac tttgtattat gatacatgct ttaaatattt
     4321 ttacgcactt tatattataa tacatgcttt aaataatctt attcgctttg tattataaca
     4381 cattatttaa atatttttac tcactctgca ttatagtaca ttatttaaat atttttcttc
     4441 gctttgcatt atgatacatt atttaaatat ttttactcac cttgtattat ggtacattat
     4501 ctaaatattt ttcttcactc tgtattatga tatataactt aaatatttta cctcactcta
     4561 caatattata tataatttaa atatttttct tcactttgta tactaaagtt tatttaaagt
     4621 attttctttc ccattatact atgctgttaa atatttttca actgaagtat tgtagaacct
     4681 taaaattact ataaaaaact atattctaaa atacttgtaa tactacgtat cacccttaac
     4741 acttaagtat aattttaaag caaaattctt attacttata tttaattttg attctacatc
     4801 tttagatata attttaagta atttaagaaa ttattgtaaa tcatatagta ctactcaata
     4861 attaggtttt tcaatgttcc aattatgttt ctttgatata atccaccatg actaaaaact
     4921 atcgtttcta tatcataatt acttatattt ttaatagcat cttttaactc ttgtttgttg
     4981 ctgtgcatta catcaacagg cttaagttct ccattttcta cctgtaacaa atctccagca
     5041 ataagtactt tagactcttt taaataaaga catatgtgac ctctagtgtg acctcctgta
     5101 tgtataactt ctatttcctc acctagattc aatttttcat ggttatctaa tgacacatct
     5161 actttagtat atgatgattt aaatccaagt cccataacat ttagcatact aagcatctta
     5221 tcatcaattt tatctaccat ttgttccaac atataaagtt taaaaggagt ttcttctcct
     5281 gttatatagc tgatttcact tttgtatgca tatactttga tattattctt agatttttct
     5341 cttagataat ttatgtttcc tatatggtct atatcatgat gagtaattat tatatttttt
     5401 aacttatcaa agctcgtgtt acttttatta agagcatcaa ttattaaatc accttgaccc
     5461 ggaagacctg tgtcaataag tgttgcatca tcttctgtgt agattacagg aatatacata
     5521 actttatctt caccgaatac atttgatgaa atttttaaaa catctaatcc ctttgctaaa
     5581 ttcataattt ttctccttat aattacttaa ttagaggtca atttaattaa agaaattgag
     5641 aaaatgtaga ttttcctcta gttatatttt attaattaaa aattattaat acctagtata
     5701 tcacttaagt tgaaggatta ctcgacttga tttttttgtt attttatggt atagtaatta
     5761 atatagaagt aagtaattgc aagctttgca attactttta tttttttcta ataactattt
     5821 tatttttgat aattcgtata aaattaaaag taaagtaata tggaaaatat gaatatagaa
     5881 aaactttaat aagaaaataa attatgaata aataaaagaa acgcaatact gtatatagat
     5941 gattatttag aaaaataaaa tctcttttaa taaaaataag cttcaaaata aacttttagt
     6001 tcataaagct taggaggaac taaattgagt gcaagtgtat ctactgttca aaataaatag
     6061 ttcataaagc actctttttt atattaaatc aattatattt tcgtcatttc agcaatgaaa
     6121 aagaaactta tctctatttt gagacagctt ctttttatta acttcctact ttttattagt
     6181 tttctaaaat tgaaaagctt tatttatagg attccttaga tttatatttt gacgatataa
     6241 ttttttaaaa acatcttaaa agatggtata caatacacac aatcatactc ataattgaaa
     6301 aataatcaat ggaaaataaa attactggat attatctatt aaaaaataca aattgattca
     6361 caagaaacat ataatctata atattatgat gttactctct cgcaccaagt aactttattt
     6421 tcaagtaacc ttttaaattc ataccatcta acttcactca ataaaaatgg caatataaat
     6481 atgtactcta ttttttactt ttaaatatct gacaagcttt atatactatt ggaagtaaaa
     6541 tacaaagtaa aacagcccaa tctggtaaat gtggcatata aaagtccccc ttaccttata
     6601 caagctcctt attactaaaa attttaatag aaataaacat tgaagctaac agtataatta
     6661 aacttaaaag gaacaataca atattcacta tcatggatgg atactgatat ataaatggaa
     6721 tttcaaaatt gctgtgagct atagttaatg gtaatacaaa tgatgaagcc atgattatca
     6781 ccacgaaaaa gaattttgtt gtttcatatc ctaatttata ttgaataggc atataaactc
     6841 cataaataat agaacttatt aataaaacaa tcaaaatata tgttaagtca aaagttccta
     6901 tttgtggaat aagtaaattt tcaatccagt aaactaatgt acaatagata aataccattg
     6961 caaataaaac atacttagat tgaactaagc cacgtctagg ataaggagtt gaacaaagta
     7021 atacagatgc ttttgaatat tgactctcct ttaataatag atactggcac agcataaatt
     7081 ctgaaaatat aatggatagt acaaatccca atatttgtgc aaatggaggt aaacgccaca
     7141 atgtaaataa tgggattcct attgcaataa acaatatcaa caatacatat ttttttacaa
     7201 tcagaatatc ttttttaact aaatgaatca acataattac tctctccttt caatatatgc
     7261 aagcataata tcttcaattg taggacgctc tattaaaata tctggcatat ttttttgcac
     7321 ttcattaatt tttgaggtaa tccctataaa accataacct gtaatttcta aatttaaaaa
     7381 taattttttg atttcatcat ttagaaattg aatatcccct tttacttttc tatgttcgtc
     7441 caatagagta tctttttcac gctctaatat aatacgtcca ttgtcaatca taacaatcat
     7501 atctgctatt ttgtctaaat cagatgttat atgagtggaa aagaaaacac cacgaccaca
     7561 ttttttcata tatcctgtta gtatgtcaag tatctgacta cggattagtg ggtctaaacc
     7621 acttgtaggt tcatccataa ttaaaaactc agctttatgc gataatgcta atgctaatgc
     7681 aaatttcatt ttcattcctt ttgaaagtgt atcaatcttt tgttttgggt taagattaaa
     7741 acgcttcata ttttgttgat aatcttcttc acaccaatta tcatatgaag gtgcaataat
     7801 acttttcatt tctgccattg acaactcctc atagaaatat gaatcatcaa atacaactcc
     7861 aattcgattt tttaattcct tctcatttcc atcgaaatct ttaccaaaga tttttatttt
     7921 tccactatca cgctttacga catccaatat cgaacggatt gttgttgttt ttcctgctcc
     7981 attaacacct ataaatccag ttatacaatc ttctggtaat gcaaagctta tattagataa
     8041 tgaaaaatcg gtataagtct tatttaagtt ataaacttct aaaatatttt ccatattaat
     8101 cctcctgata tagaatatcc atcatttctt gtaactctat ctgtgtaatt cctagtgctt
     8161 ttgcatcctt aatcatatct gccatttttt gttcaactat acgtctcttt gagtctctta
     8221 gtatttctaa atttccagtt gaaataaatg ttcctattcc aacttggcgt gtaagaaagc
     8281 cttcattttc aagttcttca tacactcgtc taatagtcaa aatactaact tttaaatcat
     8341 tagcaaaatt tcttatggat ggcattgcat ccccttcttt cagttcttca gtaaatattg
     8401 cttctttaat ttgctcttta atttgttggt ataatggctt atctgatgtg ttagaaatga
     8461 gcactttcat tttttatcac ccccttttta tcattttcag tgtgatgttg ttatatacac
     8521 actatacact tagagcactt ttttgtcaat ataaaagatg taaaatatta ctatgacaaa
     8581 ataaatatga atgaaatatt agagattgtt gatagctata aacacttttt aaaaccacat
     8641 aagatagaat gtattaaata tttattaaaa gtaagaattg aatatctaaa aaaaagagga
     8701 atcctgtatg aatgatttgt ttgatgataa attaagttat aaactattta taaaaaacat
     8761 aaaggaataa atccatttct aattacaaac atactaaaaa atttagatag taataaatag
     8821 atagtaataa atagatagta ataaatggga tgaatttata agaatttgga tagaggaaag
     8881 agttattcaa gagtgtagac tagaggtaaa ctctatatta aaaaaattta aatttggata
     8941 ttatgatgca tggaatattt gcagaagtaa ccttgctata agtatagaag atttttttga
     9001 ttacaaaaga taatactcta aaatgtgagg atttcaacat tcaatactgt actttaaata
     9061 atatcactgc aaaataccat ccacctttta ccataattga ataccctaat tattttaaaa
     9121 aagaaaacat tagaaacaga aaaccttgga tatataaaat aaaaaatact aacttctaaa
     9181 acacggatac tctttgataa ataaaacaaa aaataatttt aataattaaa attggctatc
     9241 tcaaactaga gataagtctc tttctcactt ttaaaacgtt gaaaatatat tcgatttcgt
     9301 acaaaaaaga gtgccttaga actaaaaagt tcactttgtg gcactccctt ttttctcctc
     9361 tttttaattt tttataaaaa ttcttcaaaa atattattaa ataccctata ttatacataa
     9421 atcaaattaa agttgcattt tagcaaataa aaacaaatta taactattag catagcaaat
     9481 aaaaaatctg ctctcttata aaatcaaatt ataattataa aaagaaaata ttcttataac
     9541 aaattagcta atataaaatt attttataaa ttaatactac tttttagctt ctcctataaa
     9601 ttaataccac ttttttaact ttgaaaccta tctacaacat tggtaccata agaccagcta
     9661 ccacaataga aatcatacaa gccataccac caactaccag cttaggcata atcttagaca
     9721 tcaaatatgc tctttcttct tccgtttctc caacagcatt acacacttca tttgaaatta
     9781 aatatgtagt tgggaatccc aacatctgac aaaaccctac tccaaaagca agaggtttag
     9841 aaccgataat tttccaacct ggtaacacct tcatcataag gaatatacca atgatagaag
     9901 ctgcaaacat acccacaatt ggtacaaaaa gactaattaa atctgtcaaa gaaacttttg
     9961 ctaaagaagg aataacagct gcaaacacaa ccatgttgat aaatcccttg atttttcctt
    10021 tttccaaaat gtcttttggc acaataccaa tacgtgttac aataacacca acaacaagac
    10081 atacaataga ataatttaca tgaataatct ctgaaagttc ataccctaga taagagaata
    10141 atgctataaa aaatatacaa acatttgtag aataatattt atcgtatttt tcacagaaag
    10201 cttgttttac ttttgtgcct gtattctctg cttctttctt atcagtatca acatttgcta
    10261 aatcaatgcc ttttgatttt gcttcatgat attctactaa aagacggttt gcctcttgta
    10321 acgctgctct tgaagctatt ggtgtaccaa taaacttctg aattgcaaat acaactgttg
    10381 ctgtagctgc tgcaagtgtc agtccttttt ctagtgctgc ttgtgtcata atagtagtag
    10441 caggtaaagc tccatttata actggtatgc ttgtcaatac tgttgatttt ccaaacaaag
    10501 gaatacataa tgagacacag actataactg ctacaattcc aagccatgct gtcaatactg
    10561 ttctccattc gtctataaat tgtttaacat tcaacattgt tcccatacta aacataatca
    10621 ttggaacact ccaactagct gctgcggtca tacctgcttt ttcaataata tcagctggta
    10681 ttgcttttgt gacaaataga atcaaaaata aaagtagtgt aacaaataca gctgatactt
    10741 ttgcttttgt tttgcttgca attaaatccc caatagcaaa taaaactaat acgacactaa
    10801 accataataa catatcactc atagaataac ccccttatta taaatatctt tcaaaccaat
    10861 ctacaatagc atttgctctt gcaattctat tagatggtct tccatttcta gacaatccat
    10921 gtgtatctcc gtggaacaaa tacatttctg tatctacacc aagctgtttt aatgctgtaa
    10981 acatttggaa agtatccccc ataaaacatc tataatccct atcactatgt aagaacaatg
    11041 ttggtgtctt aacatttttc acatatttaa taggtgaatg attccaaaga acctcctcat
    11101 gattccaagg cgtcttatct ccacaagtct gcttcataat tctatcccca aagtcaataa
    11161 ttaaagaagc tgtaatcaag ttactaatac ctctttgaga aactgctgct ttgaaacggt
    11221 ctgtatgacc aattatccag tttgtcatat aaccaccgta acttccccct gcaaccccta
    11281 agcggtctgc atcaatccca ggatattttt caatacaagt atctacaaat tccataagat
    11341 gctcatagtc aacatacccc catctttcta ccatttctaa gaatttttca ccataaccgt
    11401 caccaccatg agggttacaa taaatcacat acattccctt tgatgttaca cactgcttca
    11461 agtgtgtaaa catatagcca tatgcccatt taggcccacc atgaatgaac aatacagcag
    11521 gatatttttc gccttcttta gcatctatag gtggtataac aaaaccatca acttcttctt
    11581 tattttttgc tacaaacgtc aatttttcag gtaatgaaac cttatgagta tctaaatatg
    11641 gtttagaaaa agcagtcatt tttttcattg tacctgtagt catatcaatg ctatatattt
    11701 ctgctaactc ataatctttc aacattactg tgtacatggt gttgtcataa atatcaaaag
    11761 atgtaaaagc atctactttt gtgatgatac gtatattacc tgtctttgta tcaaactcat
    11821 taaattctgt catagttctg caaattcttg caccaataaa tttatctcct ataactttat
    11881 tactacgtcc accaccatat actgcatcta catccagtaa tgtagcatac ataccatctg
    11941 gactagcaat catatttatt tcactagtac tcaaatcaag tataaaaata tcatgattct
    12001 gtgtaataga acggtctaat gttgaagctt gcaacattac tttatctttg ccaatatatt
    12061 ttgccaaact tatttggtac tttccttgtg gtacaagttc tttggtttca ccactgtcta
    12121 tatgatactc ccaaagtcca gaaaaaggag ttgcacaatc ttcataaatc tgaccagtat
    12181 ataaaattct gtttttatcc gaagaaacat ctatacctgc tacttcacaa aattttggtg
    12241 taatggcttt tgttatattt tcaccttctt gatataattc taatgttaca cgtcttcttt
    12301 gagaaaaatt ttctccatct cttataaaag gtttatctgt aaatgtccaa taatctacac
    12361 cctctactgc cctatctggt tctgattttt tagaatccgt tggatttttt gttgtcagta
    12421 accacaattt atttccaagt gatacaggta cgctacaagc ttttggaata gaaaatgctt
    12481 tttttgcttc tcctccttct atagaaatag tgtaaaaatc tgttgtacct gcttttggct
    12541 tatttctttt agatgtaaaa agtagttctg tattagaaat ccaactaaat gatgttacat
    12601 cttttgtttg agtcatatgt atttgttttt ctgttttgat gtccatcaca tataagtcat
    12661 gttcatagca gtctttttcc tcgttgatat ttgatataat ataagcaata tgctttccat
    12721 caggtgaaca agaaatatca tgagggaata tatattcaaa aatatctgaa ctttcaatct
    12781 ttattttttc catttttata ttctcctttc tactgtccta tgttatcttt ttttatatat
    12841 accgaaaacc aatctagcat ttcaactaat ctttgtagct tttgttttgg tctaccagaa
    12901 cgagacagtt catggttttc tccttcaaat agacaaagtt ttgtaggaca cccatgaatt
    12961 ttcaatgctg aaaacatctg gaatgcttct tgcatatagc atctatagtc tttttcacca
    13021 tgtaaaaata aagtcggtgt aacacattta tcaacataag caagaggtga ctgtttccat
    13081 tgaagctcgt ggttttccat atgagaagca cctgtttgtc ctttgcagaa ataataacca
    13141 atgtctgttg taccctccat gccactccag tttgcaatag aacgctgagc acaagcaaca
    13201 gcaaaacggt ttgtatgacc aattatccaa ttcgtcataa atccaccata acttccacct
    13261 tcaacagcca attttgtttt atcaatgtct gtatattttt caagtacagt atctgtaaat
    13321 tccataaaat ctatataatc aatttctcca aactgtttcc taatatctgc aaaagcattg
    13381 ccacgacctt cagaccccct tgggttacag aagaatacaa agtaacctgc acttgtaaat
    13441 acctgtatct catgcataaa atatggtcca tatgtcaatc ttggtcctcc atgaatcgcc
    13501 aatacagctg gatatttttt ccccacctca taatctactg gtttatatac gtatccttgt
    13561 atttcccatt tagaacttcc ttttgactct atgtattctg gcacagaaat tttatattcc
    13621 tctaaaatat ggtcatttaa atgtgttttc ttacacaatg ttccattctc tactgtataa
    13681 acttctggta atccatttcc taaacaaccc acacatacaa tattgccatc ttttacatct
    13741 ataaaatcaa ctgaacctgt ctgtgttact ttttcctgtt ttcctgttgg aatatgtatt
    13801 ctttcaataa tgcagtccat atctactgta gaagtgtaat aaatatattc tccatctacc
    13861 tttgttgtct gaccagcacc cattttaaca tcagatgtta ctgtatttcc aatacaatga
    13921 tgttgatgcc ctgaaagaag tttcatttct ttcgtatcaa tatcaatagt ataaaaatct
    13981 ccattttctc catttccata agataaagca tcagttaggt ttagtatcac ttgattttga
    14041 tataattcaa aaccttttat aatatactta tctttttcta atatacagac atttgtgttt
    14101 gtgtttgtat caaatacata gaccccattt ttcaaacctt ttacatcttt aaattcttgc
    14161 cctatatata agatttttcc atcacttatt ttcataccta caacattaaa cataggtgct
    14221 gtaattgcct tcaactcatt tatattacta tcgtatacat ataggcgttt tctttttctg
    14281 ctaatatatc cctccccatt gacagcataa ggaatttctt tgaaatgttc ataatgtctt
    14341 ttgttataag catttatttt tttctgttgt tcttcttctg gcaatccctc tacaataggt
    14401 cggtcattgt cataagaatc aataactgca tacaaacctt ttcctatagg attcaattta
    14461 ccacctttga tagggagtct aaaaagttct tctgcttctc caccatttaa agataaagca
    14521 tagtaactca tgcattgctt accgtttttg acagcttctt ttactttttc atttcgcaaa
    14581 gcagggaaca agatagtatt ttcatcttcc caggcatatg ctccaacaga gtttatagac
    14641 gttatttgtt ttaattcgcc agttttattg tttaatatat aaacttggct tgtgtaacca
    14701 ttctctttga tatcagcttt ttttacaata aatgctgtat atcctccatc tggtgatatt
    14761 tggcaatcac ttataaattg atattccaaa aatgtttcac tcgtaaatag ctttttcata
    14821 gtattttcta tcctttcttt agtaattttt ttcaaactcc ctaccacctc tttcattttt
    14881 tattttaaat ttaaaataaa aaattttaaa tttaaaataa aaaattttat aaaggttatt
    14941 tttttaggaa gccttctggc ttccttgtaa tatttgtaat ttaaagtata tttaatccat
    15001 gcttaattca tgcttaattc atacttaatc tatacttaat ctatacttag tccatactta
    15061 atctatattt aattcatact tagacttat
//
LOCUS       DAMJWC010000090        13079 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMJWC010000090 DAMJWC010000000
VERSION     DAMJWC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.093"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(73..282)
                     /locus_tag="PC503_003214"
                     /pseudo
     CDS             complement(73..282)
                     /locus_tag="PC503_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
     gene            complement(384..932)
                     /locus_tag="PC503_003215"
                     /pseudo
     CDS             complement(384..932)
                     /locus_tag="PC503_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1291..3201)
                     /gene="phnW"
                     /locus_tag="PC503_003216"
     CDS             complement(1291..3201)
                     /gene="phnW"
                     /locus_tag="PC503_003216"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF2529174.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(3480..4265)
                     /locus_tag="PC503_003217"
     CDS             complement(3480..4265)
                     /locus_tag="PC503_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2529175.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(4482..4712)
                     /gene="dltC"
                     /locus_tag="PC503_003218"
     CDS             complement(4482..4712)
                     /gene="dltC"
                     /locus_tag="PC503_003218"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF2529176.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(4731..5879)
                     /gene="dltB"
                     /locus_tag="PC503_003219"
     CDS             complement(4731..5879)
                     /gene="dltB"
                     /locus_tag="PC503_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF2529177.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(5879..7393)
                     /locus_tag="PC503_003220"
     CDS             complement(5879..7393)
                     /locus_tag="PC503_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF2529178.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(7514..8704)
                     /gene="dltD"
                     /locus_tag="PC503_003221"
     CDS             complement(7514..8704)
                     /gene="dltD"
                     /locus_tag="PC503_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF2529179.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(8992..10011)
                     /locus_tag="PC503_003222"
     CDS             complement(8992..10011)
                     /locus_tag="PC503_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2529180.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(10187..10726)
                     /locus_tag="PC503_003223"
     CDS             complement(10187..10726)
                     /locus_tag="PC503_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2529181.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(10827..11507)
                     /locus_tag="PC503_003224"
     CDS             complement(10827..11507)
                     /locus_tag="PC503_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF2529182.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(11536..12825)
                     /locus_tag="PC503_003225"
     CDS             complement(11536..12825)
                     /locus_tag="PC503_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2529183.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         4217 a         2344 c         1254 g         5264 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac aagtgtgcat
       61 agctattttt taatcaagag aagtctcttc tttcatagac aatattaact ctattctttc
      121 tagtatttta tctcttggaa agaaagtctc ttgacctgta aaagctgatt tttttataaa
      181 ccattcctct ggtattatgt tttttctttt ccatctatat aattgtccat aagatatatt
      241 agttttgctc aataaatctt tcttagatat taattcttcc atagctcttc tagcccacct
      301 ttatactgtt ttttacagta gaattatctg aaactgataa attatcactg tattcaatat
      361 ttccaacatc ataattatct actagagata tgcttttttt ctagcatacg aaattttttg
      421 caataatctc catgcccctt ttttatattt atactacttg ctccaacttc attaaaatta
      481 gaagttccat ttaaactaat attaacttct tcacaattca aaaatccatt acactccaag
      541 attccactta aattgatatt ttcacaatct atattctcat ttgcttttaa atatccttct
      601 ccatgaataa tatccgattt tatacttcct tctacattaa taattccact agtatcaatt
      661 tcaacagaat taatatttcc tgtacatcta agaagtcccg atatctcaac ttttgatgcc
      721 agtatgtttc cttctacttt acttaaacca gatgtaaaaa attcattaca ttctgttgtc
      781 ccaaaaactt ttgctgaacc agaagaatca aatttactac attttacact tccttctatt
      841 ttgcctgttc ctgatatatt aacattatca aaaattccac ctttacattt tccaacacca
      901 tcaaatctta gtgaacttaa ttcttcattc ataatgatat cctttcttta ccgtatttta
      961 tctttaaacc taatataaca aaacattgtt acgttgtcaa gtatgataat aatacttaat
     1021 aaagcaacta tcatttattt tctataaata ggcataaaaa taatagggaa atgctttatt
     1081 taaactataa atctaatttc ttagattgtg gtttaaataa aatatatccc tattactcaa
     1141 tgtttatata ttcattgtat aaacttctaa aatataagtc tttaaattct actgtcaata
     1201 ctttttatac actgtttgtg ctatcatctc acacacctaa aggagtaggc tttgcgcact
     1261 attctgtaac ctacaagaca ctatcttctt ctatctattg ataaattttt ctattacatc
     1321 agctagtctc tccatatcag ttggatagac ttcacctatg ctacctattc taaatgtatc
     1381 tatatcagtc aatttacctg gatagataac aaatccatta tcttttaaat aagtataaaa
     1441 ttccataaat tcaaactttg catttttagg atataagaaa gttgttatta caggtgattg
     1501 agcattatca ttcaccaaag tatcaaagcc taaagatttt aatcttgaag ctattgtaaa
     1561 ctgattttct ttatatctag catatctttt ttcaacagaa ccttcttctt ccaattctaa
     1621 taaagcttga taaaaagctc ttacaacatg tgtaggtgaa gtaaatctcc atttaccatt
     1681 atttttctcc atagtctccc attgcgcata cacatcaaga gataatgatt tagctatacc
     1741 tttacattta gataatttct ctttattagc tattataaaa ccaaatccag gtactccttg
     1801 tatacatttg ttagaactac taactaaaaa atctatatta aaatcttcaa catcaatctc
     1861 aattccccca aaactactca tagcatcaac tatataaatt ttgttatatt cttttgcaag
     1921 tttccctacc tcttgtatag gatttaatct acctgtagta gtttcacagt gaaccattga
     1981 tatatgtgtt atatccttgt tttcttttaa taaattttct actacattta aatccactgc
     2041 ttctatatct ttaaatgtgc agtcaacaaa ttgtatgtta agataattac atatatcttt
     2101 cattctcttt ccatatgctc catttgcaat tacaagaagt ttaccatctt ttgaaatagt
     2161 acttcctatt atagcttcta ctgaaaaagt cccacttcct tgcattaata cacttgtgta
     2221 tttatctgta ttttgggttg ctagagatac taatcttctt ctaacatctt gtactaggtt
     2281 attatattca acatcccaag tacaccaatc ttttaacata gatgctctta ctgatttagt
     2341 agtagatagt ggtcctggtg taagtaatat gtaatcattt tctggtacaa aatctgattt
     2401 aatagtttca ttctctattt ttattagtat atcttctaac tcagccatag tttctattac
     2461 aaaatgtgca cctgcctctt taaatttctt tgaaactata ctcatcttag cttttaattc
     2521 ttccttatcc atgttctcta cttcttcttg tgtaagccct aactcacttg aaccttttat
     2581 tacagcaaca ctccacattc ctgcatttac gccttctttt acatcactta ttgtatctcc
     2641 tacttttacc atagaactca taggagacac ccctaaagct tcagcatttt tatagcacat
     2701 ccaaggatac ggtcttcctt gagatacttc tgatggtgtt acaagaaaat cgggtgagta
     2761 tcctttcttt gctgcatttg gttcaactat gttcatcatc tctcttgtat aacccgttgt
     2821 agaacctatt tttaatccat tttttctcaa cttttcaata gtttcaacaa catgaggaat
     2881 tggagtcgta tactcttcta atgtctcaaa taacattggc tcaaattcag cataaagttc
     2941 atttacatca tcttcagttg gcactttacc aaacttatct gaccaaatat tctttattct
     3001 atccatttca cacatttctc ttatatggtc tatttttaat tttcccatag gttttcttgc
     3061 ttcttccatt gttacatcta tacctcttct tttaaatatc tctataaata cattaagagg
     3121 tgcaaaacat ccataatcta ctgttgttcc agcccaatcg aatactactg cttttatttt
     3181 ttctccatat atctttttca tatttatagc ctccatagat tctttttaga atttttgtgt
     3241 ttttaattgt ttttactttt aaagtataac tttcatatgt taattataca tcatatttag
     3301 gttaaatata tattaaattt ctgtttttag ttgtatttag ttgtttttat tttgtatcat
     3361 attcccataa aatcctaagt tacaatctaa aatttacttt ctaatcttaa tctatgaact
     3421 gactatattt tatgaattta gttgtattga gcatagttgt attatataaa actaagggtt
     3481 tattttgctt ctatccatgt tatatttatc tcatttaact tatccttcca ttcattcgga
     3541 ggttctacat cacaaataac aaaatctaat tcctctaaat ctgctatctt atacatacta
     3601 gcaattccta ttttagaact atcacataat acaaaacttt cctttgaatt ttttatatat
     3661 tcttttgaca acaatgcctt attttggtct atactactaa ttccaaaact atcaagtata
     3721 ccttcactag atataaaagc tttatctacg tataagtttt tcatagtatc tattgacatt
     3781 ggacatgctg tcctttggtg ttttaaattt acttttccac caataaatat aacttctcca
     3841 tcaaacaaac cttgattctc ataagaaatc aattttgata gaactggata agagtttgta
     3901 ataattttta aattgtttac agatattata taatctacaa tctgcaaatt ggtagtacct
     3961 tcatctatga taattgactc attgtcattt acaaacttag ctgcatattt agcaatactt
     4021 tgctttttat ctaggttagt attgtttctc tttatatgtt ctggttcaat cactccataa
     4081 tttattttta tagcaccacc atataccttt tttaatttat tttcattttc taattcttcc
     4141 aaatatcttc ttattgtttc tgatgatact tctaatcttt ttactaattc tttagtgttt
     4201 accttccctt ttgaatctaa taatttaagt atttcttttt ttctatctat cgaatttaaa
     4261 gacattcatt ttcctcctaa atataatata tttttctcct ataatattac aatgatacct
     4321 aagatttatg aaatcatatt tatgtattaa attttttact taattaaagt tattttcaaa
     4381 agactttgta ttatcattaa aaaagtccat caaatattag tatcagatgg actttgtaaa
     4441 attttatttt ataaattaat atttaaagtc taactactaa tttattttct tgtctccaag
     4501 aattttacta aattatttac agtagacata tcttttctct ctaaatcagt tggttgaagc
     4561 tctatcccta atctattttc aatttcaagt aaaacttcaa ttatagctaa tgagtctaaa
     4621 agttccgtct caaataaatt aaggtctaaa tcttctctta tctcatcagt ccctaataca
     4681 tcttcaaata tttctataac tgtttcttgc ataaattttc ctccttaaaa ttaagctaaa
     4741 taacctgaga atatcagcaa tccaaaacac acaatatgga atgtaatgaa aatctgcact
     4801 ctctcgaacc atttatcttt tttatgtttt ttataaaatt tagattttcg ctgatatata
     4861 tcagttaaca caagtgccaa tccttggtat acaccataag caacataata ccaagttaga
     4921 ccatgccaaa atcccattgt tatcatggtt atcatctgag ccacatgagc agcagtagtc
     4981 cttttcttaa atcttttctt tctcattgat gacataacaa atctagaaaa aatataatct
     5041 ccaaaccatc ttgaaagact tatatgccat cttgtccaga actctttcat atctttactg
     5101 ataaatggct tgtcaaagtt tataggtact tgtattccaa atatgtatcc tgtacctata
     5161 gcaaataaac tatatcctgc aaaatcaaag aacaggtata aactatatgc gtacatataa
     5221 cttaaaatat ttataaaact catatcttta ggtattcttg atacccaata tgtatttatc
     5281 aaaaatgcta taacaaactt ataacctact cccatgacaa tattttttat tcctggcagt
     5341 aagtattctt ctatatactc ttttctagag atttgttttt ccaagtcctg ttcaaatctt
     5401 cttgacctat caataggtcc agaacttaaa gttggaaaaa ataacataaa ataaagcatc
     5461 tttgaaattt taacttcttt tatagctcca tcataaattt caataaccat ttgtatagtt
     5521 ctgaaattta agtatgatat tccaataaat ccaattattc caaaagaagt aactggagat
     5581 attttattta ttattattgg gagcattgat gcaaacaaga atccccaata tatgtattta
     5641 tttttagttt ttcttcttac atattcatat cctttaacta ttattacttc aagaataata
     5701 aatattacca agtactttag ttggacatca attcctacta ttaagaatat cataaacaaa
     5761 cttgccaaca taccataata ctttatattc ttgcccatta gacctaaaat tactgctggt
     5821 attgatgtta ataataatat ataaagataa aaataatctc catattgtga aaaaatcatt
     5881 aaatttcctc cataagtttc tttctgtcta ttttaccatt gatatttgtt ggaaactcag
     5941 agattattga aatatttctt ggaatcatat atgaaggtat atactttcca agttcctttt
     6001 ttattatcat cccattttta atattactta aatcattctt ttcatttaac tcaacaatac
     6061 cttttaagta agcaattttt tcgtccttat atactggtaa aactactgca ttttttacat
     6121 tatgtacttt tctcaaatta ttttctatat cttctatttc aattctaaat ccatttaatt
     6181 taatctgaaa atcttttctt ccacaataat atatatttcc atctaaaaga tatcccatat
     6241 ctccagtttt ataagctctc cactttacac catctatttc atcatagaaa aatacttcat
     6301 cagtcttttc tttattattg aagtaacctt tagaaactga tggtccaatt attataattt
     6361 cacccttttc attttcttta agctcatttc catcttcatc aagtattttt attttacaat
     6421 ttgacatagg gtatccaact ggaagacttt tttcatcatc tatagccttt tgagtcatat
     6481 catttacact tacaccaaca gtagcctcgg ttggtccata tccattgata attcttgtgt
     6541 ttggaaatct actcataagt tctttagtaa gattttttga aagtgcttct cctatgaata
     6601 tcattgactc aaggttagga agcattttac tattaaactc tttttcagtt atacatactc
     6661 ctgcaaaaga aggagttgac acccatacag ctatatctga gatactaaat tgtctaaata
     6721 gttctttata gtctgctaat acatcttttg atattgaaaa taatgtagct ccatggataa
     6781 gaccagggta tattgttgta actgaaaggt caaaagaata tgctggttgg ttcattatta
     6841 ctttttcact tccatctatg tttagatatg ggcttatcca atctgaaaag ctatctaaat
     6901 tgtttgaact tatttgaacc ccttttggct ttcctgtact tcctgaagta aatagtatat
     6961 atgcattttc atcatctttt acccagtttt ctttatctaa tgattttccc tgatattcat
     7021 ttattatata atttaattta tccatatcaa ttacattgat atctccaaaa tctttttcat
     7081 cactaaagtt aaataatacc tttggtttta tctctttagt gacttcaaaa actctatcaa
     7141 ttggaaaact aatatcaaga ggcacatacg ctctacctga ttttaaagct cctatcatac
     7201 atgccattat catgttttct ttatttccat aaattactat aggagtatct tcttctttgt
     7261 atacatcctt tagaaatact gatatagcat ctgaatattc atttaaatct ttataagaaa
     7321 gtttatctcc attacacatt agtgctgttc tatctgtatt tgaatatttt tttattcctt
     7381 caataatttt catataagaa tgctccttta aaatccgtta taaataaatg gcaattcttt
     7441 aaatggagta aatgttagaa ctcctatcgc caatattata accatagtta aacaaatact
     7501 agttaacaaa tctttattgt tctttaaata ttttaaataa tctctcacag acatctaccc
     7561 atcctttcgt accaagatgc attacatccc ttaaataata cttatctgac cctttatctt
     7621 taaggtttag aacttcaaag cctttgcttt ctgctatttt ttgtgcttta tcgtagtact
     7681 gatttctttc tttttcagaa ataccagtca aattatagaa tttatccata cttgggatta
     7741 atacaacaac tggcttaata cctaagtcag tacatacatt tagcatcagt ttataatttt
     7801 caaactcctt agatgttaat aaatttacat ctttgtctct tcctttgtat tgctctatac
     7861 catctttaaa atgctcttta taatagtact tatcaatatt tagtggattt ttaccaactc
     7921 tttttttagc atcttcaatg gctttctttc tctcatatga ccaatttatt ggtctttttc
     7981 tttttgttgc tctcttttta tctagcttaa ttaatcgttt ataaagaata cccttttctt
     8041 taagagctat acaatacttt cttccttgaa aataaggctc taaaagcacc ttttcagctt
     8101 tttcaggaaa tgtcttaggc tcatatagct tagcatataa tgcttctgct ttatactcgt
     8161 cacttcccca taataactta cttgattttt ttgcatattc aatcttattt tgtttagata
     8221 tttttggatt atctaaaaat cgataaaatt gtattggtga aaatctagac tgataatggt
     8281 gacttgtgac tccgtctttt tccataaacc attgcataga aattaacaag acaactttct
     8341 tattatcaat attaggattc atacttccta atattgcagc atcttgtaat gtctgagtat
     8401 aggctctccc aattgcaaac accttatttt tactcctatt tgtattaaaa tagtactttg
     8461 gatgttgttt tgttgaatta ctaagttctg atgaccccaa aatcataata tccttttctc
     8521 ttaaaaaatg attatttgct gtaacccctt tatcttttat atcacttaaa gtatcatcca
     8581 taattggaag tagatttttc tccctcaaaa gttcatcagt tttagaatca agaaatttgt
     8641 ctaacccaaa taaaaatact acgcctatta taaaaggtgt aataaagtat atcaattttc
     8701 tcatattttc tctcctctaa aaatattcaa atttatgtta ttattaatca tattagtttt
     8761 gatatgtata ttcaactaca aaattgtaat aaaatcgtca aaactttttt tgatactgtt
     8821 acaaaattgt aaaaaaaaag aaaaaaacgc caaaaataaa tttcttttta gcactttttc
     8881 atacttataa tttgacattt taacacttgg ttaagtatac accttacctt aacttaaaat
     8941 taaatttatt taagaatata tattataaat tcttatattt tctaatataa actatatact
     9001 atcagctgga taaacaatac tactttgtct tcttatctca tccataattt ccattactat
     9061 tattgaattt tcatgagaat ttatatttga ttctatttta ttgttattta taagacttat
     9121 aaactctaca agttcataat acattccttc tatttctcta ggcttttcct ctgctttttc
     9181 ttttggaata gatatatctt cttctcttcc atctctgtat ttaataatag ctttttcaaa
     9241 tagattaagc ttttcaatta ttatacttcc ctcttctcct tgtatttcag atggtatata
     9301 agaatcagct actttagaat actgaattat cgcatccata tcatcatatt gaaatacagc
     9361 tgaaccttct ccatccactc cagtttgaag tatatgagaa actgccttta cagtttttgg
     9421 agcaccaaat aaattcacca taggatgtat acaatacact cctatatcca ttaaagctcc
     9481 atttgacaac tcttttttaa aggcattttc tataattcca tttttatatt tatcatatct
     9541 tgaagaatac tgacaatagc ttccaaaaaa tcttcttatt ttccctattt tatataagtt
     9601 ttctttaact gctttaaagt ttggaacaca tgtaattctc atagcttcca taagcaatac
     9661 attattatct ttggctgttt ttatcattga tttgacttct tttaaattag atgctaacga
     9721 cttttcacaa agcacatgtt ttttgtgttt taaacaagta atggtttgct ttgaatgtaa
     9781 tgcatttgga gaagctatgt atacagcatc tatatccttc gatttagcca tttgttctaa
     9841 atcatcaaaa aaaatacttg ctccatatag agttccaaat tctctagctt tttctaaatt
     9901 tctagaatat acagcaacca attcaaagtc tttaacccta gatgcagctc ttagaaatat
     9961 atttgctata ttgcttgtcc caacaatacc aaatcttatt ttacccatca taaatcactc
    10021 cccattttct acactttatt ttaattttaa taaaaaactt tacaacttat agatatatta
    10081 taaaataatt ttatcaaata aaaaagaaag ctaattttaa atgatttcac cattttaaca
    10141 tagctttctt ttaactacaa tctaaattca acttatattt ttaaagttat ctttctacta
    10201 tatctttatt tcccctcaaa aattttatag taagaatttc atccacaaac aatgttacta
    10261 aaagtatagt tacaacaatt ggccaataag gtattataag actatataaa ctatcaacta
    10321 tatacacttg aaaatatcta actccaataa atgtcaatat agtccaatat acagaaaact
    10381 ttagacatac tattcctcta ctattgtact tataatctga ataatcccaa tagaccttat
    10441 taaaatatac tttcataagt attcctgtaa tatattctac tactgtcggc actactagac
    10501 ataataaaag caatgcaaat atattattgg ggtcaataaa tcttgagacc tctattataa
    10561 tcgacattgc aattgcatac attggtttaa atggaccatt taaaaatcca tcttcttgaa
    10621 aatgcccttg tttataataa ctatataagt tttcaattat ccaacctata aaaccataca
    10681 agaaaaaatt aaataaaaaa tataatagag aacctacatt atccatgaat attcctccta
    10741 gctgtttata cttatttttt ctcatattca tggatttatt ctaaatcaaa gaaattatat
    10801 ttaatttatt taattaatac tttatattat agattgtgac attctttaga gttcaaactt
    10861 tttaggtatt ctctaacttc cagtaaattt tcaagtatct tatgtgattg tgatttaatt
    10921 tgctcatctg gctcttttaa atctggtaca tttatacatc ttataccacc attgtatgca
    10981 gcttcaactc ccataggcga atcctctatg acaatacaat tttggggatt aacatttatc
    11041 tttttagctg cttttaagaa tatctcaggg tttggtttag agtttacaac atcatctcca
    11101 caaactatag catcaaagta atcttttaaa tttgccttag ctaatctctt tactgctctt
    11161 tctctctttg ttgatgttgc aacagccatt ttgtatccat tttcctttaa aaaagagatt
    11221 agttcattga ctcctaattt gataggagct cccttcctct ccataaattc aatcatattt
    11281 ttagtttttt cgtcatataa atctattatt ggtacagaac tatcgtatat atctgtaaga
    11341 ccttctatta ttcctttacg atttcttccc ataactgatg tataaatttc cttagtcata
    11401 gtatatccat acttttcaaa cgtctccatc caaaattcaa gagaaattct ctctgagtca
    11461 aacaaaactc catccatgtc aaaaataatt ccttctactt tttgcataca attcctccaa
    11521 tattttttga tataattata ttacactttt tatgattaat tttacaaccc tcaatttatc
    11581 caattctaat attgtaaaat tgtaattttc aaaagttaca ctttggttta ctttaatatt
    11641 tgaaccaagc atataggata tccacccacc tatactgtca aatccatcat gctctatatc
    11701 aagtccaaaa tacttattaa tatagttgat agattcagtt ccatcaacta agtaagaacc
    11761 tgctcctatt ttcttaatat gagtctcttc tttgtcaaat tcatcttgaa tttctccaac
    11821 tatctcttct agtatatctt ctattgttac cacaccagat gtaccaccat attcatccac
    11881 aactatagca agttgaagtt tttcctttct tattctctca agagctttat ctatagttaa
    11941 attttcagat atatatataa tatctctcaa tatttcttct agttcaattt tattttcatt
    12001 tatcttttga ttgtataaat ctcttatatg tacaaaacct aatatatcat ctttattttt
    12061 tctgcatact ggatatcttg taacaccttc ctcttttaaa atagctaata tcttttcttc
    12121 agaatcactt tcatatatac ataccatatc agttctagga accattatct ctctaatttt
    12181 cttttcttca aattcaaaaa tattatcaac taatctttgc tctgattcat ctataagtcc
    12241 acttttataa ctttcttcta ctaatagtct tatttcgtca cctgtatggg gttcatcaac
    12301 ctcatcagct tgtgaatatc caaatggttt aagaaataaa tcagtactta agttgaaaaa
    12361 atatattatt ggatatgtta acttataaaa tcctactaat aaaaaagatg tactcaacat
    12421 tattttttct gtattataaa gtgctaaagc tttaggaacc aactctccta ttacaacctc
    12481 catcattgtt ataattaaaa aagaaatgga aattgatata gtatatataa tactttcact
    12541 aagattaaat acacttacta ttggtaaaat taactcttta actgtagatt ctcccatcca
    12601 acctaatgca agtgaacaaa gtgttatacc aagttgacat gcagaaagat aggaatttaa
    12661 gttgtctttt attattttac atctttttgc attattatta ccttcagtta tcatggtatc
    12721 aatcctagaa ctacgaagtt ttaccatagc aaattcacaa gctacaaaaa aagcatttat
    12781 caaaacaagc attactataa gtgttacttt taataactcc cgcataaagt attggttctt
    12841 ataatgtaag aaatctataa gaactcaaag ttcccccctt atattaataa atttaattta
    12901 taatatatat tctatcatat ttattaatat atcctacttt attacaaata atttttataa
    12961 actaaataac cccttttaat atttatgact ggctatttga taaatattaa aggggttatt
    13021 tagttatcat tttttatttc taaaaatctt ttctcaaatg atttagttat ctatttatc
//
LOCUS       DAMJWC010000091        12875 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMJWC010000091 DAMJWC010000000
VERSION     DAMJWC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.094"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            116..304
                     /locus_tag="PC503_003226"
     CDS             116..304
                     /locus_tag="PC503_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF2529184.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(464..616)
                     /locus_tag="PC503_003227"
     CDS             complement(464..616)
                     /locus_tag="PC503_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF2529185.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(714..1190)
                     /locus_tag="PC503_003228"
     CDS             complement(714..1190)
                     /locus_tag="PC503_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2529186.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1409..2170
                     /locus_tag="PC503_003229"
     CDS             1409..2170
                     /locus_tag="PC503_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2529187.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2430..4358)
                     /locus_tag="PC503_003230"
     CDS             complement(2430..4358)
                     /locus_tag="PC503_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2529188.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSENSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4592..5044
                     /locus_tag="PC503_003231"
     CDS             4592..5044
                     /locus_tag="PC503_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2529189.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5047..5355
                     /locus_tag="PC503_003232"
     CDS             5047..5355
                     /locus_tag="PC503_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2529190.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5469..6575
                     /locus_tag="PC503_003233"
     CDS             5469..6575
                     /locus_tag="PC503_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2529191.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6650..9328
                     /gene="mngB"
                     /locus_tag="PC503_003234"
     CDS             6650..9328
                     /gene="mngB"
                     /locus_tag="PC503_003234"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2529192.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIVKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9645..11978)
                     /locus_tag="PC503_003235"
     CDS             complement(9645..11978)
                     /locus_tag="PC503_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2529193.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11953..12669)
                     /locus_tag="PC503_003236"
     CDS             complement(11953..12669)
                     /locus_tag="PC503_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529194.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4797 a         1794 c         1672 g         4612 t
ORIGIN      
        1 ttcttcaata tgtgtaaggc aaatatatat ttctattgca aatttttgtt atttatgata
       61 atataaatat gtttttagtc tttaaatagt tatcatttta aggaggtgtg cgtagatggc
      121 aaaagtatgt agcgtatgtg gtaaaggtaa ggtttctgga aaccaagtat cacactcaaa
      181 taaacataat aaaagaacat ggtcagctaa cttaagaagc gtaagagcga ttatagatgg
      241 agctcctaag agagtaaaag tttgtactag atgtttacgt tctggtaaaa ttgaaagagc
      301 ttagtaacca cgtttaaaag cctacttccg taagtaggct ttttaattta atcattttta
      361 ctctttctca taaattttag gattatactt gaaatccatt ttggtaattt tattgttact
      421 actttcatca atactcaccc cacactttat agttaaaact attttaacaa aaaaataata
      481 atgctccaca tccaataagt attaatgcgg taagtgctga ccaaatccag ccaggaagca
      541 acattgacag aattacagcc attcctgttg ctagacaaag tattcctagc aataccttag
      601 acttgttatt tctcatggaa cacctccaca tagaacctgt atctataaat attttcatat
      661 tcaagtttat gcgacagttt tccattttag accaataaac acattatgta attttaattt
      721 ttcatactag aattattact gaactccgat atagattcta caatatccaa aattcctttt
      781 tttctactta acctttcagg tccactatat aaaacaactg gtataacttt aggaagttta
      841 aaatttttat cttctatttc ttcaaggctt tttttcataa taaaactttt ccaaatttgt
      901 tctctatacg atttcaatct tgggacaatt tcagtatcca tttctgtttg aaattctaac
      961 actatataat gtgatacttt gccgctttta gaaaatacct tataaattat atcaacttct
     1021 tttcctttat attcacatat aaaagatgtt tctaactcta tatttttaag agttaattct
     1081 tttgctattg agacacttgt aaaattttga atcaaactta aaaaactttc tttatctgaa
     1141 tacattcttc tgtactcttc tcgtttttca ttgcttcttt ttaaattcat acagttcctc
     1201 ctagactata gaccttctat tttttagtaa agatagtcta taaattttat tttttaattt
     1261 tcactagtga gtattgacag ttgtgtgtaa aatatccagt aaagatattt ttttatattt
     1321 ttattaaaag atataaattt ttatatttta atgtattgac atttacgttg cgtaaaagtg
     1381 tatatttaat ttataggagg tactacttat ggaatataca gttcaaaaat taagtaaact
     1441 agctggtata agtactagaa cacttagata ttatgatgaa ataggtcttc ttaagccact
     1501 taaaataaat tcttcaggtt atcgtatata tggtcaaaat gaagttaata aacttcaaca
     1561 aatacttttt tatagagaat taggaattaa cttagaaaat ataaaaaaca ttataaattc
     1621 accaaacttc gatagtttaa gtgcgttaaa agaacaccat aataaattac tagccaaaag
     1681 aaagcaaatt gatttactaa tagaaaatgt aactaaaact atagctctga aggagggaaa
     1741 atacactatg acagatatag aaaaatttga aggttttaaa gaaaagatga ttgatgaaaa
     1801 tgaaaaaaat tatggaactg aaattagaga gaaatatggt aaagatatta tagatacatc
     1861 aaataaaaaa cttaaaaata tgtctaagca agattatgaa aattggcaaa acctaaatat
     1921 cgaaataatt agtaaactta aaaaagcttt taaaactggt gatgcctcta gtgaactggc
     1981 tcaggaagtt gcaaaattac atcataaatg gttgtgttac acttggaaca catactctaa
     2041 agaagctcat tcctctctag cacagatgta tgtatatgat gaacgtttta catcatatta
     2101 tgatagagaa caacctggat tagctaagtt tttaagggat gctatagtaa tatatacaag
     2161 agataaataa tataaaataa taaaggtggt gtctcaaaat gaacttttta gttcatgaga
     2221 cactcttttt tgtatgaaat cagatatatt tttatcattt tatcaatgaa aaacaggttt
     2281 ctctctctat tttgagacag aatctttatt gtataataat tataatcaat acaaaataat
     2341 aacaaattat acaaaactta cttatactat ttatgctaaa aacaaaaaat attttattaa
     2401 agtttttaaa acttatgtaa tataaaaatc tatactatag acttgattat ggaaagaaaa
     2461 ttatcaaaat cattacaatt agatatacta tctctaatat cattgtcatg aattatcttt
     2521 aaaaggatat cataaatgga gtttattttt atataatcat ctttatttat agccaacatc
     2581 atgattaatt taacagtaga attttcactc caatatattg gttcattcaa tatggaaata
     2641 caaatcttag ttcttataga gcttaattcc ataggatgag gtatagctaa aaaatcatct
     2701 atattggtag aagataaact ttctctgtaa aatacagatt cagcaaatga tggaaataca
     2761 atttcacttt gagttaattt gttgcacatc aactttataa gctcatcttt atctttgatt
     2821 ttaggattaa caataaataa atttttatca aagaaattgt ccaaaagatt actataaata
     2881 tgggaattat tagtgattga cttagatata ttctctatat ctttttttaa tagttttaaa
     2941 tccactaata caataggaat actatcatga tttaaaggaa ttgtcgatat tattatatct
     3001 acatctgaca attcactagc taaaaattga ttaaatgata gacattgaag tatatttatt
     3061 ttatcatgaa aaactttgtt taattgaacc tctaataacc tacttgaacc ataccctgaa
     3121 ccacatacta atactacgtt tttacactta atattacttt gaaaaaatct ctctattcca
     3181 gcacctatat gcagggatac atatccaatt tcatcttctg ttaaagagta aatactattt
     3241 ttaaaaactt tttctatagc atttaaagtt atttcaaatg ctaaaggata attactcttt
     3301 attgtattta taaggggatt caccttattt aaattataag atttagaatt gagaattgat
     3361 ttaaagtgca gtactaaatc atcaaataat acactatcat ttctaaggtc aaaagtatat
     3421 tgattgttga ttacttctaa aatttcttca acatactcta taattttagt atctacccta
     3481 ttggaaacgt tatccaaaag agaactttta gttataaaat gattatatag ataaactctg
     3541 tctgcctttg aaataattat agtatattta ctctcaatat aattaaatat attttcaaca
     3601 gttgtattcg attgaaaatc tgttaaaaca acatctaaaa cattatctaa gcagtaacca
     3661 tcaagtattc tacttacagt aatagctaaa tggataataa agttttttag attaaaatct
     3721 aggaaattga tattaaattt attaatttca cttaacacta ccctttgaag ctctattaaa
     3781 tctacattat taaataattc tatttctcta tctgtaattc caattatata gttttcaaaa
     3841 ttcctattta tcatattatt agaaatacat cttcgaatat ctatttcctt accttcaact
     3901 ttaactccat aatatggctt agaaactaat attaaattat actttgacaa aataggcttt
     3961 attcttttta tgtcatttag tattgtaaat ttactcacat acaagctatt agctaaatct
     4021 tctagtttta tatatgtatt gttatagaga atatatttta aaatatattg atttctttct
     4081 ataggagaat ctggtatttc acttgaatcc ataatatcat cagatattaa tgctagatac
     4141 tgttggtata atgctaaatt aagaatatct atataatatc cttctccttt ttttatttta
     4201 ataatagcac catttttctc taaagttcca tttatagaag taatatcatt tcttatagtt
     4261 ctctcactca cttttaaatg attacttaaa gttttacaag taattttatc atcactttca
     4321 tttaataatt taaacaacgt gagcaatctc ttgtgcataa atatcccccc ttatagaatt
     4381 tcttctaaat tatactattt acactcatat aatacaatta ctctaataaa attgtattat
     4441 aataatttat ttccacttct atatggaaat tagttattat cataatataa atttccatgt
     4501 cgaagtggaa attagttata tttaatttaa ttaggataat gattacaata taaatataag
     4561 ttaagacatt atgaatggag tggaaaaata tatggtacta caagaaaaat atatatttat
     4621 agataaagac ttaaaaagca aagaagaagt attaaatttt attgcagata gtgcttatat
     4681 actaggtatt acaactaata aagaggctct tttaaaagac cttctaaaaa gagaaaatga
     4741 atttccaaca ggaataaaag atggatttgc gatacctcat acaaagagtg taaatgtaaa
     4801 ggaagcttcc atactctata ttaaaacaac taacgagtta gaatggaaaa ctttagatga
     4861 tagtaaggtt agatatgtat ttagtttgtt agccccacat aaaaatgaag gaaatataca
     4921 tttgaaaact ctatctaaat tagccacatg tttaatggag gatgatttta caagtgaagt
     4981 taaaaatgct agtgatgcaa gtcatttagt aaaatatata actaataaaa tgaaggagga
     5041 ataattatga aaatagtagc tataacatca tgtatagcag gattagcaca cacacctatg
     5101 gcagcaaaag ctttagaaca agctgcatca aaaatgggtc atgaaatcaa agtagaacaa
     5161 caaggtgcta tgggacgagt aaatactata acaaaagaag aagcacaaga tgcggacttt
     5221 atacttatag catctgacca aactatatct ggaatggaaa gatttgatgg taaaaaagtg
     5281 ataaaagtca aaataggtat agcgttaaaa aaaccagaag ctgtcttaac aaagtgtata
     5341 gaagctattt cttaataaaa aaatctcact ctaatataga atgagaaaaa tcaaaaatta
     5401 aaaaattgtc taatgtaatt ataacatatt atcaaaaaat ataacaaact tatataggag
     5461 gattaaaaat gagtaaaaaa aataaatctc ttttaagtga acttaaggga cacttaatga
     5521 caggtatctc atatatgttg ccacttgtaa taggctcatc tttagttgta gctatcccaa
     5581 agcttacagc tttagcagtg ggtataacaa gtttagatgc ttataaaaat gtatctggtt
     5641 tttatcatat tctttactta atggaacaag ttggttggac tggcataggt ctattaaata
     5701 cggtattagc aggatttata gcattttcaa taggtgagaa accagctatg ggtgcaggtt
     5761 ttattggtgg gctcatagca agtaatacta atgcaggatt cttaggagca gtaatagcag
     5821 gtttctttgc tgggtatgtt tgtaagtttt taaagaaaaa aattaaaata tctgggtcag
     5881 catcaggaat gatgccactt ataataatgc cacttataac agttggatta actggttttt
     5941 taatgagtgt tgtattagca ggacctttag gaaacataaa tacttcatta aatgcttggg
     6001 tagctgaaat gtgtcaaaat ggaacaaatt cggtggtatt ggctttaatt ttaggcgcaa
     6061 tgataggatt cgatttaggt ggaccagtaa ataaagcagc ttggatggca ggaaatgcat
     6121 tattgttaga gggaatctat ctaccagcga tattggtaaa ctgcgcaata gttatacctc
     6181 cactaggata tggtttagct acattcataa gaaaatcaaa attttccaat gcattagctg
     6241 aaacaggaaa aggcaatata gttatgggta taattggaat aacagaaggt gcaattcctt
     6301 tcactttaac aaatccatta aaattagttc ctgttaatat gataggatgc gctttgggtg
     6361 taggattatc agctttgtta ggtgtacatg ctataatgcc tccagttggt ggattatatg
     6421 gatttatatc aataggttct ggatgggctt acttagtagg tgcaatattt ggagctttag
     6481 taatagcaat attatcaaca actttagtag acttcaatga agatgaaact acggaaaata
     6541 cagaatttga tgaaatagag ttagatataa tgtaaattaa aaacttaatt ttagataatt
     6601 gagaattgag tgtactctca attctcaatt aaattttggg aggattttta tgaaaaagac
     6661 aaaagtacat gtagttccac acagtcattg ggatagagaa tggtatttta caacatcaag
     6721 gtcaaaaata tatttaatga aagattttca agatatatta gacatattgg aagaaaaaga
     6781 agactttaaa tactttacta tggatgcaca agcttctctc ttagatgatt atttaaaatg
     6841 gagacctcag gataaatata gaataagaga tttagttcaa agaagaagat tagttattgg
     6901 accttggtat actcaaacag accaattggt tatatcagga gaatctataa ttagaaacct
     6961 ttactatgga atagatagat gcaatgaatt tggtgaacct atgagggttg gatatgtacc
     7021 agattctttt gggcaatcag ctcaaatgcc acaaatatac agaggttttg gaatagatag
     7081 ttcattattt tggcgtggag tttctgatga tatggtagat acaacagagt ttatatggaa
     7141 aggttctgat ggttcaaaag tattagcagt tcaaatacca tttggttatt actatggagg
     7201 taatatacca gaagatgatt cagatttaaa agaatattta aaagatataa tcgtaaaact
     7261 taaggttaaa gcttctacta ataacgtata ttttccaaat ggatttgacc aagcaccaat
     7321 aagaaaaaac cttcctgata tattaaaaaa agctaatgaa atagataatg aaaatgaata
     7381 cgaaataagt gatatagaaa actatataga ttcagtaaga aatgaaagaa atgaatttac
     7441 agagcttaaa ggtgaatttt taaatgctaa acatatgaga atacacaaat ccatattctc
     7501 ctcaaggtca gaccttaaaa taatgaataa caaattagaa aattatatta caaatgtact
     7561 tgaaccgtta ttaacattaa gttattcact tggaaatgaa taccctcacc tagttataaa
     7621 agatatatgg aaacttatgt ttgaaaatgc agctcatgac agcataggtt cttgtaatag
     7681 tgacacaaca aatgaggatg tatacacaag atacaaacaa gccagagatt tgagtataaa
     7741 tttattagat ttgcatatga gacttataag tactcaaatc aaaaataata atgaagaaat
     7801 aacattaaca gtattcaatg gattcccaga agtcagaaat gaagttgtag aatttgatac
     7861 ttatattcca ggtcaagatt ttgtgataaa gaataaaaat ggaaaaattc ttaattatat
     7921 aataaaagaa aaagaagata ttacaaatta tatattaact caaacaataa gattaaaccc
     7981 aagtaaaaaa atatatatac ccaaaactgt atatagagca aaaattgcac tttcagtaaa
     8041 agatatacca ccaatgggat atactcaact agtttttgaa ttggatacta aaaataaatg
     8101 tgaaatagaa acaagtaatt gcaaggaaat agaaaacaaa tactacaaaa taacagccaa
     8161 taaaaatggt tcattagaaa tattagataa agaatctaat aagacttata aaaaccaagc
     8221 tgtaattgaa gacaatggag atgatggaga ttcatacaac tattctcctc caagaaaaga
     8281 tatttatgtt tcatctttag attctgtatc ttcagtagaa gtgctaaaat caaacattca
     8341 agaagaaatg atacttaaat attcattgac cataccagct tcactggaag aaagggctat
     8401 aggtaaagtt tctgtgaaaa tgccagtaac aatgaaaatc accttagaac ctaaagaaca
     8461 aataattaag tttaatgtta atataaaaaa taaccaagca ctatctcata gagtaagagt
     8521 tttatttaat acagaaatag catctaagtt ttctatagca gatcaacaat ttggaataat
     8581 acaaagacca acagtattag aaaaagacct tgcattgtgg aaaagagaca attactcatg
     8641 gcaagaaaaa cctataacta tcgaaccaat gcaaagtttt gttactttag aggatggaca
     8701 aagaggaata gcattaataa ctggttgtgt aagagaatat caaatagttg gtgataattt
     8761 agatacaata gcattaacac tattcaggtc atttggatat atgggaagag aaaatttact
     8821 ttatagacca ggaagagctt ctggagaaaa aataatagca acaccagatg cacaattact
     8881 taaagagtta aactttgact ttggtcttta catatataac aataaatttg atgaagcaaa
     8941 tgtagctaat acagctaaga gattcttaac acctatacaa atatatgaat atgctgattt
     9001 tttaaatggt agacttatat ttgcattcaa tgacgaaaaa caaatatatg aaaatgaatt
     9061 tagtttgatg aatgtaaata attcaaattt cacagtaagt gcaataaaga aagaagaaaa
     9121 aggagatgga attgtagtta gaatcttcaa tggtatgaaa aatgaggatg ctaagggaag
     9181 tcttaacatc aataaaaatg tcaatgatgc ttatagtgca atgctcgacg aaatctatga
     9241 taatactagc aagcttaaag taaatactaa aactgtagag gtaaattctt tatcacattg
     9301 taaagtacaa acaatagtaa ttaaataata taaaatagct tatacaagat ttcaaaataa
     9361 attgctagta ccatgttaat agtaaagcca gatattatgc tatttataag ctctgtaaca
     9421 ctaaataaca ttttgtaaaa taaaaaggtg aaccttgtat attaggattc acctttttta
     9481 aataaatcaa cattctgttt taaaataaca tttataagct gttttgaaat aatgcttaca
     9541 aattatttta aaacaatacc tataaatttt tatttaaaga atacacataa atatttccag
     9601 actcttttat cctatagact ttataattat taaagaagtc taatctaatt tttgttaaaa
     9661 gtaattgtaa ctttaaataa atcaccatcc acacttatat tcatcttacc accctgtaat
     9721 tctataaaac tttttgctat cgctaaacca agaccagaac cttctgtgtt acgtgattta
     9781 tctcctctta caaatctctc cattatatca tctacactaa aatcaatctc agatgcagac
     9841 atatttttaa gcataatatt tactttatta tctgtttcta aaatatcaat atacactctt
     9901 gaatttggca ttgcatattt gcttatattt attataagat tttcaaatac tctaaatgta
     9961 cgctgactat ctaatggtaa tattattttt tcattagaaa agttattctt tactattaga
    10021 gatgaatctg caagtttgtc atctaattct aaaagtgtct gcttcattag agatacaata
    10081 tccacattta ctatattcaa ataaacatct ccactatttg ccttgcttac ttcaaacaaa
    10141 tcttctatta gatgttgcaa tctttgtgac tttctgtcta atgtatcaat atacaactta
    10201 cgattttcat ctgttatact ttcatctttt aataaatcta tataagtgat tatagatgtt
    10261 agaggtgttt ttaagtcatg tgatacattt gatataagct ctgttttcat cttttgactc
    10321 ttaacctctt cgtcaacagc ttttttaaat ccagtttgaa tatttcctaa ttcgtctttt
    10381 ataggattaa aaaatcctaa atctttttcc atatttacat ctaagtttcc atctgaaatt
    10441 ttctttgtaa catctaaaag ttgattatat tcatatattg tctttttaga gtaatctgac
    10501 agtattttaa ataatactac tgaatatatt aatgcgagta ttattccaaa gaaccacata
    10561 ctacacatta taactataat caataaattt attcccaaaa ttgtaactat agttttattt
    10621 ggcttttctt ttagatttat tgttctaatt tgattaataa ctgtttttcc tgcttttttt
    10681 agccatacaa aaaacattcc tgtcacagta tgttttgtaa aatactctct tattccaaca
    10741 tttaaaatat gttttaaaag tattataaat acaaatatta ttgagaatat tacaaaccaa
    10801 taagttaaat tcattaaact taccaatata ctagccattt tagcacttat gtcattgttt
    10861 ataaggtact ctacataatt cccactcaag gtattactta ttataacagt aggatataaa
    10921 tctacaagcc cctgtataat agcaagagca ataaagagta tctctaacgg tattcttgat
    10981 aatgtatcaa atcctagcaa ctctttagat tttctatatg ggaatgctaa agctacaata
    11041 acaactatag ctaatataat ttttaaaatc attccagaaa tcttataata agaattattt
    11101 tctacattgc ttatatatga aattatacca tcatcaaaat aagtatttcc ataaccatac
    11161 tctacactat cacctttact tattacttta ggtacagcat atactaatgt tatatttttt
    11221 attggagata acttatatga aattgaattt cctcctaaac ttgtatccat taaatcttct
    11281 cttgctttag ataacaacat ttgattaata attttttgat ttactccata agaatccaca
    11341 atatttactt ttccatcttt atcaaaattc attacaacgt agaatctata gttttctttt
    11401 atatctgtaa tctgcttttg tctttcctca tcattcattt ctgtattttt tgactgattt
    11461 tcatcagaat tttcttttga agcatcattt tttgttgtat caagtactcc taattcttta
    11521 ttatcattaa aaaattcaaa attgctttct ttatcaacta aatagtactt taaattcttt
    11581 cctgacgctt taatgaaatg ctcccaattt tcaaagtttt cattaaaatc tgcattaata
    11641 ctatcatctg tatagtaagt ttctgaacca tcataagtat ctttttcttt acttacattt
    11701 tttatatagt tcatagtttc ttcattgata aatagttttg atggttgtat catcttacct
    11761 tcttgttctt ccttcatatt atgatataaa acataacttc ctttatatat actatctaca
    11821 aagctttcct gttcaaatgg attctctgct ccacctttag cacttgcttg tatagtagaa
    11881 tattgactaa tcatacctaa tgatgctgat aacataagta taaaaactat aatagtaact
    11941 atatatttat ctttaaattt tttcaatttt gtatccaaca ccccacacca cctttaaata
    12001 tttaggattt tttgggtcaa tttctatctt ttcccttata ttcctcacat gtaccataac
    12061 tgtatctgta tttacagcat tctcattcca aactctttca tatatttcat cagcagaaaa
    12121 aactcttcct gcatttctca taagtaaact tagtatttta aattctatag gagttgtttt
    12181 tatatacttt ccatcaatac taacttcttt tgtattttca tttaattcta atccgcctat
    12241 tgcaaacaca ctatcgtcac tttctacctt ttgctcttta tttccaacca tgtttagata
    12301 cttagtgtac cttctaagtt gtgaattaac tctagccaat agttctaatg gcttaaaagg
    12361 ttttgttaca taatcgtctg ctcctatatt aagccccatt attttgtcaa cttcctctga
    12421 ttttgcagat agcattatta ctggaaaatt atagttttct ctaagcttca ttgtaagtgt
    12481 tataccatcc attttaggca tcattatatc aactatagct aaatgtattt cttggttttc
    12541 tataacctta agaccttcta atccattgta tcccttaaaa acattatatc cttgatttaa
    12601 tagatatatt tctatagcat ctgctatctc cttttcatct tctaccacca aaatattata
    12661 tgaattcatt ctaatctcct ttatattaat ttataaattt tctttacata tatgattata
    12721 caatatgata gaagtttttc catttatata tatatttata tcttttgttc tggttatttg
    12781 tatttaatgt ccatcttaga aacctccttc tagtttaaat ttaatatttt ttcattttgt
    12841 tttatatact taatattaaa attaaaaact taaga
//
LOCUS       DAMJWC010000092        12799 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMJWC010000092 DAMJWC010000000
VERSION     DAMJWC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.095"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            129..1643
                     /gene="glpK"
                     /locus_tag="PC503_003237"
     CDS             129..1643
                     /gene="glpK"
                     /locus_tag="PC503_003237"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2529195.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(1757..2386)
                     /locus_tag="PC503_003238"
     CDS             complement(1757..2386)
                     /locus_tag="PC503_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2529196.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            2974..3765
                     /locus_tag="PC503_003239"
     CDS             2974..3765
                     /locus_tag="PC503_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF2529197.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            3794..5014
                     /locus_tag="PC503_003240"
     CDS             3794..5014
                     /locus_tag="PC503_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF2529198.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            5034..5729
                     /gene="pxpB"
                     /locus_tag="PC503_003241"
     CDS             5034..5729
                     /gene="pxpB"
                     /locus_tag="PC503_003241"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF2529199.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            5759..6745
                     /locus_tag="PC503_003242"
     CDS             5759..6745
                     /locus_tag="PC503_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF2529200.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGTRAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISEGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(6959..7525)
                     /locus_tag="PC503_003243"
     CDS             complement(6959..7525)
                     /locus_tag="PC503_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529201.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            7877..8944
                     /locus_tag="PC503_003244"
     CDS             7877..8944
                     /locus_tag="PC503_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF2529202.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            8963..10123
                     /locus_tag="PC503_003245"
     CDS             8963..10123
                     /locus_tag="PC503_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2529203.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVATILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            10136..12232
                     /locus_tag="PC503_003246"
     CDS             10136..12232
                     /locus_tag="PC503_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF2529204.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNGLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(12391..12735)
                     /locus_tag="PC503_003247"
     CDS             complement(12391..12735)
                     /locus_tag="PC503_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2529205.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
BASE COUNT         4880 a         1459 c         2345 g         4115 t
ORIGIN      
        1 ataagtgtct tcttactaaa tatctattat attaaatttg tacttaagta tgattattta
       61 ttgaaatatg tgatattaaa tttttctttt taataaatta aatattatat gataaggaga
      121 atatggtgat ggaaaagaag tatgtaatgg cattagacca aggaacaacc agttcaagag
      181 ctatactatt taataaaaaa ggcgaaatag tgaaaattgc acaaaaagag ttcaatcaaa
      241 tttatccaaa agctggatgg gtagagcatg accctatgga aatatggggg tcacaaagtg
      301 gggtaatgag agaagttata gaaacagcag gtataagacc agaagaaatt gcttcaatag
      361 ggataactaa tcaaagagag actacggttg tttggagtag gtatactggt aaacctattt
      421 ataacgcaat agtatggcag tgtaggagaa cgtcagaaat atgtgatgaa cttaaaaata
      481 aaggattgga agaatcaata aaagaaaaaa caggtctttt aatagatgca tacttttcag
      541 caacaaaagt aaaatggata ttagataatg tagaaggagc tagggaaaaa gcagaacaag
      601 gagagttatt atttggaact atagatacat ggttaatatg gaatttaact cgtggaaaag
      661 tacatgtaac agattactca aatgcatcta gaacaatgat gtacaatata aatgatttag
      721 aatgggatga ggatatatta cgagaattgg acataccaat aagcatgttg ccattagtaa
      781 aaccttctag ctatgtttat ggtcatacag atgagcgcat gttatcagga gctaaaatac
      841 ctattgcggg atgtgctgga gaccaacaag cagcattatt tggtcaaaat tgtgttgaag
      901 aaggtactgc aaaaaatact tatggaacgg gttgtttctt gcttatgaat acaggcagta
      961 acatagttaa atctaagcat gggttactta caacaattgc ttggggagtt gatggaaaag
     1021 taacatatgc attagaagga agtatattta ttggaggagc atctgttcaa tggcttagag
     1081 atgaattaaa gataattgaa tctgcaaaag atagtgaaat gtatgcaaat agggtagagg
     1141 atactaatgg tgtatatgta gtgccagcat ttacaggtct tggagctcca tattgggata
     1201 tgtatgctag gggttcaatt ttaggactta caagaggagc aaaaaaagaa catatagtaa
     1261 gagccacatt ggaatcaatt gcttatcaga caaaggatgt tttagaagca atgcaaaacg
     1321 attcaaaatt aaaactaaaa tcattaaaag ttgatggtgg agcaagtaat aataattttt
     1381 taatgcaatt tcaatcagat atattaaatg tagatataga tagacccaaa atagtagaaa
     1441 ctacagcttt aggagctgct tatttagcag ggttgtctgt tggattctat attggaagaa
     1501 atgaaattac ttcaaagtgg tcagtagaaa aagagtttaa tccaaatatg agtgaagaga
     1561 agagatgtaa attatataaa ggatggaaaa aagctgtatc gagagcttta agctgggaaa
     1621 aagaagatga attggatatt taaaaattaa tcaaagttaa atttatttga atttaaaaag
     1681 agctttatgt aaaatatgaa gctctttttt tgttgttaat cttgcatttt tatataatca
     1741 cactaaatta tataatttat ttttcgtttt catataaaaa cattggtata gaattgtaaa
     1801 tgtgttggtc accaactact aagagaatgt ctccttctaa aaattcaata tatggtccag
     1861 gagatattat aagttcttca cctcttttaa ttgcaactat tgtagcacct gtattttgcc
     1921 aaaatttagt ttgtgcagct gtttgaccaa tatatttgca attagaattt atggtgaact
     1981 gaacgggcac taaaggattg attatttcaa gtctgttaga atagtctaaa attttattta
     2041 tagtatctaa tatttcattt tctaaattag atttagtatc tattaaatta taaagtgttg
     2101 atttatatga tgatatattt gtaatatctc tatatttttt tataaaagaa gaagctttgt
     2161 ctggagatag tacaataaca cctttaccct ttatgctttt aacaacgcca atgtcctcta
     2221 aaattttgac agctcttctt atcgtttctg gagatacatt gtatttacca gccaaaacag
     2281 agcgtccaaa tagtactgaa tcctcttgta tttcacccgt gtatatttta tttgcaatat
     2341 ccaacgctat tttttggtat attggcatcg tatagttttt atccattgtt tttcccccaa
     2401 tacaaaattt atgttaaaaa aatatataat cttaacaata ctattgtata atttataggt
     2461 ttatatgtct acaatatgta caaatattgt gcatgtttta aaataatatt ttaacatgca
     2521 tttagtatac atgattttat tatacttaaa actatataaa gaattaatta taaaaatata
     2581 aagatatttt acttacaaag aatgataatt atatagatga aagaaacaaa tgaatgaaga
     2641 aaaatgattc tgtcttgcat ataaagtgat taaaaatgaa aaatacttta aaaatgaagg
     2701 ttaaagccct tattttaagt gaaaataatt aattattaac taaaaaatgg taaaaagatt
     2761 ttttgaaaaa gaaatacaaa tgaatgttca attaaaataa ttgcaaaaat attccttaaa
     2821 tggtaaaatt atattaatta aatgcaatag aatagttgca aaaataaaat tgaatacaag
     2881 tgataaaata tttcatgcaa tatataaaat aaacaaaatt taaaaattaa aactacttat
     2941 tctatcaaaa tgttagcgag gaggggtcat aaattgtata aagtagattt aaatagtgat
     3001 ttaggagaaa gttttggaac gtataagatt ggtttagatg aagaagtttt aaaatatatt
     3061 tcatcagcca atatagcttg tgggtttcat gcaggtgacc ctagtcatat ggaaaaaaca
     3121 gtacagctag ctaaaaaaaa tggagtgaaa ataggcgcac atccaggttt cctagattta
     3181 ataggatttg gaagacgtga gatgaaaata acaaagcagg aagctaaaga ttatacaaaa
     3241 tatcaactgg gtgctttaat ggcatttgca agttcaaatg gatgtaatat acaacatgta
     3301 aaaccacatg gagcattata caatatggca gctaaagata aagagttagc tatggggatt
     3361 tgtgaagcta tatatgaagt cgataaagat attatactgt tggggctata taatagtgaa
     3421 atgataaatt ctgctaaaga aattggactt aggtttgcaa atgaagtatt tgcagataga
     3481 gcttatgata ataatggttt tttggttcca agaaatgtag aaggagcagt tatacatgat
     3541 acaaaacatg caatagatag ggttgttagg atggtaaaag aaggaactgt agaaacttta
     3601 acaggtgaag ttatacatat caaagcagat tctatatgtg tacatgggga caatccaaaa
     3661 gcaatagagt ttgtcaaaga aataagaaag cgttttgaat tagaaggtat agaagtttgt
     3721 ccattagaaa acatagaagt ttgttcgtca gagaacatag tataagactg ataacatgag
     3781 ggggagataa aatatgagta caaaaaatat tacagataaa actaaaaata aaaaagatgt
     3841 cggagcactt ataggggctg catttataat ggcaacatca gcaattggac cagggttttt
     3901 aactcagact gcacaattta cccaagattt tggaccgaat ttttcatttg taattttaat
     3961 tacaacaatc ctttttatag gggctcaagt aaatgtatgg agagtaattg gtgtatcagg
     4021 acttagaggt caggatatag caaataaaat aatacctgga ttaggctatt tagtagcttt
     4081 tttagtagct cttggaggat tagcttttaa tataggaaat gttggtggag ctgcacttgg
     4141 tatgaatgta atgtttaata tgaatatgac attaggaact gtattaagtg gattaatagc
     4201 tatatttgta tttatgtcaa aaaattcaaa ttctctagtc gataagataa ctaaattttt
     4261 agcattagga atgataatta tagttggata tgtagcaata tcaaatcatc ctcctgttgg
     4321 agaggcagta tcaagaatgg taaaaccaga aaatccaaaa ggactgatat tcccaataat
     4381 aactttactt ggaggaagtg ttggaggtta tataactttt gctggaggac atagattaat
     4441 agacggtgga ataacaggag aagaaaatat aaaagaaata actaaatctt ctcttttggg
     4501 tatattagtt gccacaatga tgagagttct tttattttta gcaatactgg cagtggtttc
     4561 aaaaggtctt caacttgacc cagaaaatcc agcagcttca gcttttaaat ttagtgcagg
     4621 agcaatagga tataaattct ttggacttgt attatggtct gctgcaatta catcagttat
     4681 aggagctgct tatacatcag tttctttctt aaagacacta aatcctttta tagataaata
     4741 tgaaaaatat tttataatag catttatagc aatatcaaca cttataatgg catttatagg
     4801 aaaaccagct actttattaa ttttagcagg agctttaaat ggattgatac ttccaatcac
     4861 attaggaatt atgcttatag catctaaaag aaaagatatt gttggagatt acaagcatcc
     4921 tacatggctt ttaatatttg gattaatagt agttttaata tctgcatata caggaataac
     4981 ttctcttagc agcctaggtg ctttatttgc ttaatttaga agaggtgaca tttatggaaa
     5041 ctagatactt gatatcaggg gataaggcag tggttgctga atttggaaat gagatatcag
     5101 aagatataaa caaaaaagta atttcattta tgagagcaat agaaatatcg aatcttaaag
     5161 gtattgtaac agaaatggta ccaacatata ggtcacttat gataagttat aatccattag
     5221 aaatagattt tgatagtttg attgagaatt taaaaaaaat agaagataat ttggaaagta
     5281 tagtattacc aaaacctaaa atacatgaga ttccagtatg ttatgatgag gtttttggta
     5341 tagatattaa aaacgttgca agctacaata atctcactgt agatgaagtt ataaaaatac
     5401 acacaagcag agagtacttg atatatatgc tagggtttac tcctggattt ccatatctag
     5461 gtggtatgga tgaaagaata gctacaccta gattagaagt gccaagaact aaaatttatg
     5521 gtgggagtgt tggaatagca ggttcccaga ctggtgtata tcctattgat agtcctggtg
     5581 gatggcaaat aattggtagg acacctttaa aattatatga tgaaaataga gaagaacaga
     5641 ttttgcttag agctggagac tttataaaat ttgttccaat aacattagat gaatttatag
     5701 aaatcgaaaa aaataactta agtatttaaa tatcgttata gtacagggag tggtatatat
     5761 gggattcaaa gttgaattag gaggtttcca aacattaata caagacagag gtagagttgg
     5821 ctatggtcaa tatggtgtat ctggatgtgg agcaatggat gagtatgcac atagagtagg
     5881 aaatatatta gtaggaaatt ctgaagatga ggcttcttta gaagttttaa tgttaggtcc
     5941 tacaattacc tttgatgaat atacgcaaat agcagtaact gggggagatt taggggctaa
     6001 aataaatgga aaagaaattc aaaactggag gtcatatcaa ataaatccag gtgatgtatt
     6061 atcatttaga ggtgtgaaat caggtactag agcctatgtg tcaatagctg gtggaataga
     6121 tgttccactt gcaatgggaa gtaagtcaac ttatacaaga gctaaaattg gtggatttga
     6181 aggtagagca cttaaaaaag gcgattatat aaatactttt attcaggaaa aagattttac
     6241 aataaataaa aaattaagtt caaaatatat tccaacttat agttcagaaa tcgtactaag
     6301 aattgtaaaa ggtcctcaat ttgatgcttt ttctaacggt gaagtagaga aatttttatc
     6361 aaataaatac aaagttacga atgaaataga tagaatgggt tgtagactag atggagagag
     6421 tataaagcac cttaatggag cagatattat atctgagggt atttcttatg gagctataca
     6481 agtacctggt catggaaaac ctattataat gttatcagat agacagacta gtggtggcta
     6541 tactaagata gggaacgtta taagtgtaga tttgtataag ttagcacaag caaagccaaa
     6601 tgatgtagta aaatttgaac ttgtagatat atatgaagca catagactat tgagagagca
     6661 agaagataag attcaagata tctacaagag tatgaaaaat ataagagttg taaaggcaaa
     6721 agtattaaat gatatagcag tttaatttta acaaatacaa tttttattat agtttataat
     6781 ataacttaca aatagctatt tactatttac cataattaag atggtttaga ttagtcaaat
     6841 agctattttt ttagtttgag taaatatttt aaatttaaat aaatacttca attttaaaat
     6901 aaaagcaata tttaaatcta ttatattatc tacaaaaagt aggtgtgtca tattgagttt
     6961 atttagattt tattggccaa attggaggtg atataactcc atatccacga gctattgtat
     7021 ctttacttgg attgatgatt ttatgtggta cattagcttt tataaatgtt gagtcacctg
     7081 gatttaatct aactaccttt tcacccatac aaatatcaac cacaccactc gttaccacca
     7141 taatttcttc tgatgcatga tatatataat ctttggcatc ctcactttct ggtttaagtt
     7201 caaactctac aaataaaatt gaaggtgtaa actcagttgt aggcattgga gatactatct
     7261 cgtaaaacat ttcactcttt ggaaatttca tcataactct atcttctttt ctaatgacta
     7321 aatcatcagt attattgtca tccataaaca tatataaagg agtgtctaaa acttcagcga
     7381 tttttctcaa tgaagacaag gatggttcaa tagcatctct ttctatttga gagatataac
     7441 ttatagataa atctgtcaat ttggaaacat cacttaatgt ttttttcttg ctttttctta
     7501 tatttctcat cttttcacct agcataagaa cctccaaata ataaaattaa tataaaatat
     7561 tcgcttaaaa caaagtaatt atagcacaac atagaagtag tggcaataag aatacatagt
     7621 agattttgac aattaaaatt taattaaatc caaataaaag tctatgaaaa tgaattattg
     7681 ttaaattaat acaaagaaaa taataataaa aaaatttaat agaagagtat taattgaatt
     7741 aagattatca cattatattt tggaaaagag taaattttca gtaaattatc ttgacatata
     7801 tattgaagta ataatataat ttaaagtata aaattttaaa aattgaatta taacttcaaa
     7861 aaataaggag ggtaatatga agataacaga tatcaaattt gaaaagctta gaattaaatt
     7921 aaaaaaacct gtagtagttt catttggagt aattgaatat ggagaaagta taattttaaa
     7981 aattgaaact gatgaagggt attgtggatt tggcgaagca gcgcctcttg cagcagttac
     8041 aggtgaagtt ttggataatg ttctttcagt attgcttatg tttaaaaaag agttaatagg
     8101 caaagaccca ctagatattg aaaccataca tacaatcatg gatggaatta ttataggtaa
     8161 tacttctgca aaagcagcta ttgacatagc tttatatgat attaaaggaa aaattatgaa
     8221 tgcacccctt tataaagttc ttggaggatt tgatagtaaa gtccaaacgg atattactat
     8281 aagtatagat aagccagaaa aaatggcagt agaagcttta gaaagagtaa aagaaggttt
     8341 taggatattg aagcttaaag caggtataaa tcctgaagac gatattgaag ctgtaaagtt
     8401 aattagagaa gccgttggag agagtataag aattagaatt gatgcaaatc aaggatggaa
     8461 cgtaaatagc agtataaata ctatcaaaaa gttagaagaa tttaatgttg atgcaattga
     8521 acaagcactt ccacattggg atttagatgg tactgcttac ataagaaata aaagtaatac
     8581 aaaaattatg atagatgaat cattacattc accaatagat gcaattaagg ctataaaaaa
     8641 gaatgcagtt gatacattta atattaagct gatgaaatca agtggaatat atcctgctat
     8701 aaaaatcaac aacatagctg aggcaagtgg agtaaattgt atgttaggat gtatgctgga
     8761 aacgagaatt ggtataacag cagcagcaaa tttaatagca tctaaaaaga acataacaga
     8821 agctgacctt gatagtttta tgttttgtga agaattagaa ggtatatctg gaggatttgt
     8881 aatggatgga gatattatga atcttgtcaa taaaccaggt ttaggaatag aagtaaactt
     8941 atgataaatt tggaggttaa atatgaatac acttttttca aatccaggta gtatacttgc
     9001 tgtaatgaca tcaatgattg cattgggttt ttacttacaa agatacaaag ccattaaaag
     9061 cttaggacca gcacttacaa taatcataat gggaataata ctttcaaact taaaagtagt
     9121 tccagtaagt actgagttat atggaactat ttcaacatat gctattccag tttctatgac
     9181 tataatgttg atgagtgttg acttaaaaga aatgacaaaa ttatcaagag aacctttaat
     9241 tgcaattttt gtagctgtat taactgtaag tatcatggca tttttatttg gattagtatt
     9301 tgcagaaaaa atatcagaag gttggaaggt tgctggaatg tttgtaggta catatactgg
     9361 tggaagtgct aatcttacag ctattggaac aggtcttaat gtaagtagac aaactcttgc
     9421 tgcagcaaat gcagcagact atgtaattgg agtaccaaca ttgatattta tgtttgctct
     9481 accagcaata ttaaaaaatt caaagaagtt taaaaaactt tggccatatc atgtagaaga
     9541 atcagaatta gaggattgtc aaaatgaaga atttatggag tcaaaagaat ggagtattaa
     9601 agatatagct tggatgttgg ctataggttt tgttgttaca gaagttgcaa caatacttgc
     9661 tggatatttc aattcgagtt ttagtagtgc agcaagaata cttttagtta caacaatttc
     9721 aattataatt gctcaattaa agccagtaaa gaaactaaag ggaaatttag atttaggatt
     9781 atttgttgca ttattctttt tatgtacaat aggtttttca gtagatataa aagaattttt
     9841 aggttcaact tttactataa cactttactg ttttagcata atttttgctt catttgtttt
     9901 ccatttaggc ataactagac ttttaaagat aaagtatcaa tatgtaatac tttctatagt
     9961 aggagcaatt gctgatggtc ctacttcagc tttagtagct gcttctgcaa agtggaattc
    10021 gcttgtaagt gtagcagtcg taatgggagt aattggtgga gtattaggaa attatgcagg
    10081 tatatcagtg gcatatgcaa taaagatgtc tctaggatta taggggggag tttaattgat
    10141 aaaatttaaa ttatacatat ctggactata cagtggaaat gtaatctttg atggagattt
    10201 attaattgaa aagttgaatc cttttacaaa taaaatagaa agtttaaaac caataagcaa
    10261 ggaagaaaat acatactatt taaatcttac aaaaatagat ttaaagtctt tatttaataa
    10321 ttttgatgta tatactaaaa gcttagtaaa cacagataaa gacacagtta taaataactt
    10381 aggagaaacg cattctaaac ttaatgaata tatatgggtt caaagaaaca aaaagttccc
    10441 actagatata attattgtag ataataaaat agtaggtttt atctgtttat ccagagaaac
    10501 ttgtactata ttaattatgg atggatatga agagtatact gtattaaaag aatgggaaaa
    10561 aactcataaa aatgaagaga tatattctat aagatttggt ggaaattata tgattgatat
    10621 gaaagatggt ataaaacttt ctacagatgt atatctccct gattttgtag attctaccaa
    10681 aaaagcaccg acaattctta tgagaactcc atatggaaaa gaaaatgata aagaaatata
    10741 ttataaatat gtacaaagag gatatgctgt tgtaatacaa gatgttaggg gaagaaatga
    10801 atcagaaggt aagtgggaac ctatgattca tgagagggaa gatggagata gtaccataaa
    10861 ttggatagta tcacaggaat ggtcaagtgg aatagttgga atgcttggag catcatatct
    10921 tggttatgtc caatgggcag ctgcatcttc aggcaataag catcttaaag ctttagttag
    10981 tatagtaaca tcaggaagcc cttttattga tataccaaga aaaggaggag cttttgtatc
    11041 tggtatgctt gcatgggcat ttatggtatc aagaaataaa gttgatagaa gcaaaatggt
    11101 aagagatgat tgggatgatg ttttaaacat acgaccaata gaaaatatac ctgttgaagc
    11161 tcttggatat agaattgaat ttctggaaga atggttaaag agagtagaaa aagatgagta
    11221 ttgggatttg atggattggc atttacaaaa agataaaata aatgtacctg cattggttgt
    11281 atctgggtgg tatgatgata atagtatggg aactacagag gccttagatg ttataaagga
    11341 ctatgaaaaa ggaaagagaa aggctattct aggtccatgg atgcataatt caaatacttt
    11401 aagagatata aatggtattt ctttaggaaa tagttcatta agatatgatt tggattataa
    11461 ttatctatta tggtttgata aatacttaaa aggtatagaa aataacatag atacgactgc
    11521 tccagtagag tattactctg taggttctaa taagtggaag acagaagaaa attggccaat
    11581 aataaataag atagataaaa gtatgtatct aataagtgat ggaaatgcta acacatcttt
    11641 aggaaatggt agattagtat ttgataatgg tttagaagaa aagtatgata gttatatata
    11701 taatccaaaa gacccatcag tacaactaat tgatatgtca gagaatgaag ttggagttcc
    11761 aaataactac aaagatttag aaaaaagaag tgatatgttg tgttatacat cagatgcttt
    11821 tagtgaagaa tttactgtaa caggtgatat aaagttagag ttttttgcat caagttctgc
    11881 caaagatact gactgggtta taaaaattat ggacgtggat ttagatggaa attcaattaa
    11941 attagctgat ggtatactta gtgctagatt tagaaatagt ttttataagt cagagtttat
    12001 ggaagaagga gagatttata agtttacgat tataacttca aaaatatcaa acacgtttaa
    12061 agttggtcat aaaattagac tagatataac gtctagtgct aaaaacttta ttttccaaaa
    12121 tagcaacacg acagagggat ataatagtat tgaatatata gaagcaaaga atacgattta
    12181 tcatggaggt aaatatccat ctaaattgat attgccaata gagaataagt aaatttatat
    12241 agattaaata gtgaggaggt gtctcaaaat gaatttttta gttcgtgaga cactttcttt
    12301 tatacaaaat caaatgtatt ttcatcattt caacaatgaa aaagaggctt atctctctgt
    12361 tttgagatag cctcctataa gctaaattga ttattttgta gctgcaacaa cgctcatttc
    12421 aactaacaaa tgctctctag caagtctagc ttcaacacaa gctctagcag gttcaaatcc
    12481 tttttcaacc caagcatccc aaacagagtt catagcttca aagtctttca tatctcttaa
    12541 ataaatagta acagatagca aatgttgctt atctgaacca tatttgttta ataaatcttc
    12601 tattttagct aaaacttcag ttgtttgttc aattactcct ccttcagcat gagtttgtcc
    12661 acataaataa actgtattgt tatgaactac agctctactc attcttccag ttccttcata
    12721 tctctttatt tccatatttt aaatacctcc atagttaaaa aatctattaa aaatctaaat
    12781 aataaattaa aaaaagtct
//
LOCUS       DAMJWC010000093        12737 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMJWC010000093 DAMJWC010000000
VERSION     DAMJWC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.096"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(141..2021)
                     /locus_tag="PC503_003248"
     CDS             complement(141..2021)
                     /locus_tag="PC503_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF2529206.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKVTINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGSGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGDDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVVVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2231..8194)
                     /locus_tag="PC503_003249"
     CDS             complement(2231..8194)
                     /locus_tag="PC503_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HDF2529207.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSDSESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDEQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSKSTLE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELARYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRIEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDANTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8318..8403)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8575..9978)
                     /locus_tag="PC503_003250"
     CDS             complement(8575..9978)
                     /locus_tag="PC503_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF2529208.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(10440..12335)
                     /locus_tag="PC503_003251"
     CDS             complement(10440..12335)
                     /locus_tag="PC503_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF2529209.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
BASE COUNT         3538 a         2347 c         1406 g         5446 t
ORIGIN      
        1 taaacttaat atagctcaaa ttattataca ttttaacctc aatattatta gattgttaag
       61 ataatgaaaa taaaataaga atgcatttaa atatataact ttatatctaa atacattctt
      121 attttctatt tacttaatat ttatttttca attaaactct taatcttgtc tattacagat
      181 gaggctattc ctccacctac ttcaaacaac tttgatgaat ttttaccttt taatgacgat
      241 tcttgtgatt tatctaacgt atttgtagca agtataactg gtgaattgtt tttagctgct
      301 aatggtccaa ctgctaaagc atctataagt ttatcttgat ttgcaactac aactccatct
      361 agcttagatt gagagtagaa tttatctatt actttggcat tcgtctcttg tctagtttga
      421 cctgccaccc tattgtttga tatatctttg tttgctattt ttccaacttg ttcaatagcc
      481 ttgttagata ttttttctac tccaccaata aaatatatat ttgacacctt atttgattta
      541 ataaattgtt cagcttcatt atctacacca tctttttgtg taagtactat tggagttttt
      601 tctttaccag ccagtgatgc tattgataat gaatcagctt ctccatttcc tgctcctata
      661 tacaacttgc ttacattatt cgtcttatct atttcttttg ctatattaat agaagtttga
      721 tatcttgtat ctccacctat tctttgtact gatatttttg aatttacagc tttgatagct
      781 tcaacaactg aatttggcat tgagttgttt ccacctatca caactacttt tgatggattt
      841 agccttttca attcttctac agttttttga ggaagtttat catttgatga taaaagaatc
      901 ggtgagtttt ttacactagc aagtggtgta gctgtaagcc catccaccat acttttatct
      961 tctccattta ctattacaac tgtatctgat tttgtccaac cactttgaga tattttgata
     1021 gctgtctcaa atctatcatc accttttaat tttttgactg tgacattaga tgtagaatca
     1081 cttgaatttc ctcctccaga gcttccacca ctagatgagc cgcctgaatt acttcctcca
     1141 ccattatttc caccactacc attatctggt ggtaattcat ccggttttga taattcattt
     1201 tcaactatgt attctaaact ttttggaagt gtaacttcaa catatttgtt tattgtaact
     1261 tttcttccct tagttgtttt ttgtgctaat ccaagtttta atattacatt tgaaccactt
     1321 tcttgtgttt ctttactaac aatagaatag tttatcctaa tattgtttaa taaatattca
     1381 agtgcttcac ttttctctac cttatacttt tcagggtcat ttttactaga accagttccc
     1441 ccaatcggtt ttacttcact ctcattaata agggtaaata ttaatccttc atcagagctt
     1501 atattttcat aatccactgt tttgttgtta tatgttacaa tttttaaagc tggtttatca
     1561 tttgttcctt ttcctaaaac tttatagtca gcatttgagt tacttccaga tttttttaca
     1621 gatattcttc ctatattcaa tctatttccg tctagtaagt cttcatttga tgtaacatat
     1681 atatctaatg tagttgtatt acttgatttg ttgtattctg ctctacaagt agcatttgca
     1741 tttccacttt ttatctgaga ttttatatta tcagaccaag taatcttttc tttctgctca
     1801 ttatctacta cttcaacctc accttgtact tttatactgg cttgaaatga atatactatg
     1861 ttttctactg agtccacaga tatatctata gtatttactt tctcatacgt ttttgttcct
     1921 tgtaaaactg gagctgcata tgcacatgta gcactaccag ttacagctac tgccatagtt
     1981 gatactgcta tagttcttat aaaagatttt cttttactca ttaacacccg tccttatcta
     2041 tcattaacta agtggataaa tttacttatc cacctagctt ttatatttaa tttataaatt
     2101 accctaaatt tatgattaca tttatatact ttacttttaa tatctactat tttaaaacta
     2161 ttctagtacc taatcttatt agatatacaa tgttagtgtt agtattttta cgtttttaga
     2221 gttccaccta ctatttatct ctaacaatat taccctttac tttattgctt acagttataa
     2281 ccttcttatt actgatatca atagaatttc ttgtagcttt tctagcttta ctattactat
     2341 cagtaagact tattgtcttt aactcatcat aattcttagc tcctacaggt acatacattg
     2401 tatcacttac aaatctttga cctactggag tatctccttg aaggtcattg tatctatata
     2461 gttcagcctt aaccttatca cttaaagaat caaagttttc ttttggcata tagtaaaccc
     2521 atgtaccttt actgatttca cctagttcac ctttttctgg aacttctgca aataaaagtg
     2581 cttctccaga tatagtctta ttgtttttat ctataagtag tggtaaatta aatgctggat
     2641 ttccactgta ttcacctgta ataactattg aacccgctgg aatcttacct gtttcatctt
     2701 cacttgtgct agagtcatca ctttgatata cataatcttc tgctaatttt ccaattccat
     2761 tagtacgagt ttcgtctgca ttattcattg tgccaatttc tatattatca cctggaggtc
     2821 ctattatatc taattctgca acttctatat tagacttatt atttgagatt agttttacat
     2881 atctagcttg gtatgtccaa agtttaccat ctttattaaa tgtaactcta gcttcattat
     2941 cttggtcttt tcctccacca actaaatctt gtccatattc aaaagttcct tgacttacat
     3001 cttcccagtt ctttttatca ttacttactt gtattttgta attagttaaa ggattgtatg
     3061 ttgtgctagt attctttcta aagttaaata atccttttaa tgagaacttc ctagcttctg
     3121 tctctggttt tgtatatttt agtcctacta taggtaatgt ttctttcatg tctactatta
     3181 tatatggatt ttcctctaca tttatatcag ggtctttttg agggtctttg ttccactctg
     3241 ctttacttat tatctttcct ttatatgtag tatttgcatc attatctttt atattatcaa
     3301 tttcaggatt ttgtaatggt ccatgtgagt cattttcagt tctaacatca ccgtcagaaa
     3361 cagtatttgt tatgaatgac catgctgatt tatttatttt cccttcatct gataatttta
     3421 cagtaccaac ttcaaattct tctgttggat ttaggtgata atcatatgca actaccttat
     3481 atgtaaatgc tctgttatta agaggagata tattatcagt aaatttagtc ttactatttc
     3541 cttttgcatc cacaaatcca actgttctgt attttacctg tgttccattt tcaccatcta
     3601 aataatttcc atcacttctt attatttcgt atcctagtat cttatcttta tccttatcta
     3661 catctaggtc tatagatatt ttattagatt taactagaga accactttgt attccatcag
     3721 aaaaactagc acttacttta gtatcttttg ccatactagc tatattttca tttaaaatct
     3781 ttcttctagc ttcgtcattt acatattgta tctttcttga ttctttttcg tagttcttac
     3841 tatccattat actgtttaat tctggtgtaa tttctactcc ccatgcctta aagtaatctc
     3901 ttaaatcttt ttcaacaaca cttgatgcca ttgctactag catttggtct tttggcaaac
     3961 tattaattgg gtcactactt gaaagtgctc tgtattttct tgaaatcttt gcatagaatg
     4021 tatcattact taaatcagca tctgagttat tctttaacat tgaacccgta aaatcatcat
     4081 cataagctag atgtaattgc cataacattc caagcctttc aaatacattg cttggtatac
     4141 ctaagctatt tgaagttaca tgctcatata tcttatccat tgttgaacct tcaattcttg
     4201 aatgtgtctt atcatcaaag gtctgagcaa gtaaagcaag tacattgtta ctagtttcgc
     4261 tatatgtcat ctttccaata tctgtaacat gtcctatctc atgacctatt ccccatccaa
     4321 ataagtttcc tcctgtagct tttccactat catctatttg gaaaggtact ccattcataa
     4381 gccctggaac tgaaccatat tctactccta catgtaatcc agaagcatac ataaatgctc
     4441 caataaacat tctttggtat tttatgttca tacgagattt tggagccata tcatttttag
     4501 ttaagttaaa ttcattatca tctacagttc cattaccatc taaatcttgt gttttaaata
     4561 ctcctctttc tgagtaaact aaatccatta tttgttccca tgcaagcata ctattatata
     4621 atctatctac ttgtgtattt aaatcagcat ttccttttga tatcccttga tatacagctg
     4681 ttgcaggaac atttaatgtt actttatcac tttcaatatc tgtagtgttt aacacaccag
     4741 ttttttctga atatccatat gaattaccaa catttgttcc tggataatat ggttctcctt
     4801 ttacagcatc tttatatcta gctaattctt ctatatatgc ttttatcttt ttcttagatt
     4861 cagaaactcc cgcaggactc ttatcattta ttgttccatt tagattaagg tgtggtatct
     4921 tagtagctcc tgctacacgt acttttatat ctcctccact tggagtatct tcagcgtatc
     4981 ttatgtataa acttcctcca cattctatat ctaaactatg aagtttgctt aattgaatta
     5041 cattttttcc agtgttaaga tttatttctc cactcttata tgcaccagat tctccatagt
     5101 actgtgtata tatcaactta ggagtttttc cacttttact tccaacatat actgtgattt
     5161 catctcctgc tctagcagct actcctaatg cctgccagtc attttgcata cctaaattat
     5221 tggaatttac agtatactgt ccgtttttat ctttatattt tcctaattta tttatttctt
     5281 gatttacagt agttacatca gtaagtgtgg ctctatcatt atataagtct tgagctaatt
     5341 ttaattctct ctcaataact gtcttatatg gatgatattc tccactagct ttatctggag
     5401 tatttaatct atcttttaat tcagttattt tttcttgagt tacatcttct tttaattcaa
     5461 cttgtaggtc atccataaat agatttctta catcatcttc tatactgtca tactcataaa
     5521 acttaagttc tgatatatta gacttatatg aataggatga acaaacactt acttgtatct
     5581 tggtagcagt tattggttct tttaatctaa ccattacata cttattatta tttacagggt
     5641 ctgtctttgt ttcaaaagga acatccccca gattgtgtaa ttgaccattt tcatcccaat
     5701 atcgtacctc aaagtcattt attgtcttat cagaaacatc aaaacgaggt gtagccataa
     5761 aagtatccat agtataagat ttatcaaaag ttattattgg tcctctattc gttccctcag
     5821 ctgcattata tgttgggaat gtccaatgtg ttgtaaagtc cccatctact acattgaatt
     5881 tatcaaatgg atttttatca ctatattcac ttttgtcata tcctgctgga taagtaacat
     5941 ctacaatgtg atttgttggt attccaaatc caccattctc tttaggagta ttaattaatc
     6001 tatagttagg tgttgttggt gcatccatgc tttcagttgt acctatatat gttttagaca
     6061 ttccactagt tcccaagtgg ttagtagctg tcattctaac ttcatatgtt gtattatcct
     6121 taagaccttc tatctttgaa cttgtcccac gaataagctt atcattgtat tttatccaag
     6181 acccattaga gcctttttct ttatagtaca agtcaaaatc tttagcttgt ttatgatttt
     6241 tccagcttac atcaagagat ttaaatttac ctttaacatt tataccttct ggtggttctg
     6301 gttttgtgtc tggaacaact tgaaattcta atatactatc tgggctaaat tgtataggtt
     6361 tatagtttga atctacattt tctggtactc cgtctaagtt ttctggtgtt gcatctttat
     6421 aaccactaga ccaatctcca tttaaagatt gtatgctaac cctatatagt ccatatgctt
     6481 ctatatctct aacttctatt gtatttttac tggtttgtaa ttttttagta gataatactt
     6541 ttcccttact atcaatttta tctagtataa gttcgtatgc tgatacattt acttcattat
     6601 tccaataaaa agatactttt tcatttccaa cagcagtgct agtcgatatt ttatttattt
     6661 taggtatatt catctctggc tttggtattt ctttatatac attgtttaaa aattcaactt
     6721 ttgatatttc tgcaagattt ctatcgtttg ctgttgtagc tgttattttt atagttatct
     6781 tttttactgc tacttgttta ccaagattta ttactatatc actattttga acatctgcat
     6841 atgtttctaa tgttgactta ctatatgtag atgttgtaga gttatcatct ttactgatat
     6901 taccctcttc ttttggagta tcttcatctg aattaggttt atccattgat gaattttctt
     6961 tatcattatt tttatcttga ttggtattag agtttacttc ttgtttatcg ctattttcct
     7021 gttgttcatc attattttca tctttattat ttgagttatt atcagtctgg tttatatttt
     7081 catctttatt atttacttct tcttgattta cttcttcttg ttcgttattt acttcctctt
     7141 gttgctcctc atcttttaag tttttcatat attctttgtt ttcataagga atctgttgaa
     7201 cattaccatc tttgtcagta acctcaacta ttccttttgc tggagcagta ccttctggag
     7261 cttttatatt gatgacttcc atattaagtg cttctgataa agctatatcc attactgctg
     7321 gtttttcctc agatatttca tcattttttg aagatattgt aactccatta ttttctccac
     7381 taaataaatt ttctacatta ccattaatat ctacatcact atttcctttt aattcaacct
     7441 tacttgtatc tactatagga ttggtagata ctatactttc taggcttttt gcatcttcac
     7501 tttgtcctaa atttttctgt acataatcta agtcaacaat atctaccttt ccatctctat
     7561 ttaaatcaaa ttctctttta tttgaatcta tattctctaa aaccttatta taatcactct
     7621 tatctacttt accgtctcca tttacatcac ccattaagaa caattcataa tttaaaggtt
     7681 tatttttatt atctacactt gctctattgc ttaataagac tctttgtgaa taacttgata
     7741 tatcaatgtc tttaatttct ttgttcttaa atccatctcc agagacttct acattgtatt
     7801 ttccaacagg taaattatta aatacaatat tataatatga tatattctca tctttatttt
     7861 ttatttcact tctacttgca gataattttt ttatagtata ttctatatta tctgtcccaa
     7921 catttactgt tcctgaatct ttttctccaa gctttattat tccactattg ttactatcat
     7981 cttttaatcg taactgcata ttagtcatac tttctgaatc gctatttttt attggcagtg
     8041 aaaaatttaa atctacttca agactccccc ttaacttttc tgtaactgat ttttcaactg
     8101 cccttagctt cccctctaat ataggttctg caaaaacgtt tagtggtgca ctacacatag
     8161 atactgctag tacacaagat attgcctttt tcatgaaata acaatcctcc cttaataaat
     8221 atctaatttt tcatgaattt aaatactata agtttcagac aataaaaaaa gacactcaaa
     8281 gagaatctta attataaaat aaaaagactt tactcttttt agcaactggc tgatatggct
     8341 ttaaaagctt taatccctat agttttgcgt cattagattt ccctaatttt gccatttaat
     8401 tttcactact ttcttaccca ttttatacta tatttaaact ttttaataca atttttttag
     8461 attaaattat aaaaaaataa catttatatt aatttattaa tataaatgtt attttccatt
     8521 ataatttaat tatttatata gcttccttac aagcataatt ttgtgtatat tttcttattc
     8581 tttatatctt ccataaaatt catgtgtagc atatagattc ttatctcctg ttatagctat
     8641 accaaatccc attatttcat accctttatg caacatgtta gttccttctt ctggatttgt
     8701 cttccactca ttaaaaataa agtttcctat atcatctgca tctctatttg tatatacagg
     8761 tttatctgga attttatatt taattatatt ttcaccttga actgctatat atccaggttt
     8821 aatctcactc caatctaagt atttcaaaaa agtagaatat gaattttttc catttatcgt
     8881 atgagataaa gtcttcttat ttgccattaa attagaccaa tcatttgcta aaccctctaa
     8941 tctgcttgct acagataacg ctcttactcc attctctttt ctatactgct ttgtaagagc
     9001 atatacttta ccctttattc tctctttaaa tgctctatca tttggattgt aatataaacc
     9061 ttgttgattt ggtgaagctt gatttataca ttgcttgata acattctgat ttatgcctcc
     9121 tagtacagtc aatttgtctg caccacttaa aatactcttg ttactgccat tttcaactaa
     9181 aactacagga gcattttttg ctattgtaga ggcagccaaa gcgtctgtta attgtaagcc
     9241 tttacttaga taaaattctt tactattttt ataaaactct tgtataacta tcttattagt
     9301 ttcaaatcta tctgtgccac ccaatctaat agaatttgtg ctcttaacta attcgtcgct
     9361 gattatttca ctagaaccaa gcgcataact ctttaagcct gtcgtgtcaa atcccacact
     9421 atttccatct gtaagtatta taggtactcc atctctagca gctactggtg atgcacttat
     9481 cgcatctgct tctcctgtaa atccattggc tataattact ttatctattg gcttaatttc
     9541 tttgattttt tcagctattt ttatacttgt atcaaatcta ttttcaccaa agattctttg
     9601 tacaaccttc tttttggata gtaactgatt ctcaacattt ttacttattg ttgattctga
     9661 gcctattata tacacagtct ttgctttgtt taatctttcc atagttgtgt ttggaatctg
     9721 attttgtttt gtcatcaaaa taggcgcatt taaggctcca gctaaaccac ttgcacttag
     9781 accatctgct aagctattat ctgagttgat tagtattgct gtattgtagt tttgcttatc
     9841 tgctattttt gctgctgtct catatctgtc attccctttt atttgctcaa ctgatgtcaa
     9901 cgcatttacc ataggagtat ttaccattac taaaaatagt gtaagtccta tagctaatat
     9961 ctttttacta ttcttcatat tattttctac ccccaatgta cttttcatat tttttattag
    10021 tactcatact tatttttaat caaaagttac aattttgtta ccatatttta tatatgatac
    10081 catagttatc catacaactc aaacaatata cctaaagttt ttattctcta taaattcaaa
    10141 acattataat ttattttatt taattaagtt ataagttcaa aataatttat gttaataaga
    10201 tgtttaatca ttataagaag tatcttttta taataatttt tgcaatatga atttctcaac
    10261 attataatca aaaaataaaa taaggtatct caatctaatt ctaaatgaga caccttattt
    10321 ttattatttt atcttgttat ttgtatattt tataatatct acactatgtc ttacatatta
    10381 acgcattgta taatcatata ttatctaaac aaacttttaa tattaattcc tatatcttat
    10441 tagttcttag taaataagtt tattttttct gctatttttt caatagcgtt tttagctatt
    10501 ccttcaccta tttgtactaa cttagtagca ttcttaagtc ttaactcaac tacttcttct
    10561 tgtgatttag aaagttcttc tgtagttaat actattggag cctttgaact agctgcaagt
    10621 ggtgctgctg taagtgcatc aactaattgt ccatttccac ctacataacc atcttttgct
    10681 acatatgctt tagttgcacc tgcatagtat ttattgatta ctttagcatt agtatctttt
    10741 ctattttctc cagctaatct ttcaacttta ttatttaaat ctatatcaac taatttgtct
    10801 tcaacttctt ttgatacaga attttctcca cccactattt ctaattcttt tccttttaat
    10861 aatttttcag catttgcatc taattcgtta cctgtaacta ttattggagc accaaattga
    10921 gcagctctag ctgatatact catagcatca gcttctccat ttccacctac tacaaaagca
    10981 gtcttaaatg tatcttttaa ttgttttgct atttctaaag aagtttcaaa tctatcttct
    11041 ccagaaactc tctcaacttt acttacacct aatttagaaa gtttttcttc agtttctttt
    11101 gatactttag attctccacc tactatatat attttcttag aagatagatt acttccaagt
    11161 actcttaata tttcagcttc tatttctgat ggtagtgaat cttttttaga taataatatt
    11221 ggtgcatttt tttgagaggc aagtggtgct gatgctaatc catcaactat agcatcttct
    11281 ccaactaaaa ttatagcttc tgcttctcca tctttgaatc tctctttact aacttctact
    11341 gctgttgtaa atcttgaatc accagataaa acttctactt ttaattcttt tccacctttt
    11401 acatcagtta atactttgtg taagtctcta actaacttat ggtttttact tgaaacactt
    11461 attgtttctg gcttttcatt tgccttgctt aaaactatat caaagcttga tttttctggt
    11521 ttatctttat catcactatc ttcttgttct tgagtaagga ttgcttcatt ttcaaatgtt
    11581 aaagcatatc catttttaac tttattaact atttctcttc ctaatgtagt taatctaatt
    11641 ccatcaaata attcttctgc tgatatgtct tgtaaatctg cgtttttaac tgttatcgta
    11701 tgtaattctt ttgaatctat gtcactataa ctcttttcat aaccttcaaa agtaccttct
    11761 tctgatgtta tcacttttga gaaatctaaa tgttggtctc ctacatttaa tgtaataaca
    11821 tttgctgaat cttttgctct ttttacttca actgtatttg tagattttat agttgctgtt
    11881 aacttgttat cagaatcttc tgctaaagtt gcattgtaag cattaactgc atctactatt
    11941 tcttgagcag ttttgtagtt ttcaatttta tagtcaacta cttttccacc taacacttga
    12001 tgtcctttat cttgaatagt aacttttaaa ctttgccctt ctgttaaaga gtttatctta
    12061 ttttgtaatt gagttgcatt agttaagttt acattgtcta cttttatatc gtaaactcta
    12121 tcatttacat ttgctcctgc ttttgtatct tcaaacttaa cttctaatgc ttttctaacc
    12181 tcttcgatta gtttagcaga atctttcgca cttactgtgt aatttttatc aacattttct
    12241 gtcacagtat tgtctgcgaa tattggtgct gctgcactca taactgtagc acctgccatt
    12301 actattgcca tacttctctt tttgttgctt aacatattta tgtcctccga atattatttt
    12361 ttatttttta tattcgtatt tcccacacat aaataatatt atatataata ttatttttca
    12421 atatatttta tgtgtttaca taatttacta acacaaacac taataatatc ttcttgaacc
    12481 ccttccccct gcttagctct ctataattat gctcaaagat agaaatccta ttttatagtg
    12541 attttctact aaacaatcat atactaacaa aagtattcaa actccatttt tatatactac
    12601 tatgcactaa tttttgcttt actcttatta cttaaatata tatcactaaa ttaatatcta
    12661 tctccatata ttaaaatata taacatatta taaaaatcat cataaattag agtttaaaat
    12721 taaaaattat tctaata
//
LOCUS       DAMJWC010000094        12570 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMJWC010000094 DAMJWC010000000
VERSION     DAMJWC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12570
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.097"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            173..868
                     /gene="cas6"
                     /locus_tag="PC503_003252"
     CDS             173..868
                     /gene="cas6"
                     /locus_tag="PC503_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2529210.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQHSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            859..2619
                     /locus_tag="PC503_003253"
     CDS             859..2619
                     /locus_tag="PC503_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HDF2529211.1"
                     /translation="MVIGGENLLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKN
                     FSNIDILEVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKK
                     ENLRPDKNNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLN
                     KIRLWIKTNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIID
                     GKNYGLPNDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLTNKAANGEE
                     VIYISSEKGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIP
                     IEYERHNLKPNLEIGYINNLIKLEKTIDTVFFNKFMCNSYFKEIKNINLSDLVLRDIL
                     IRHREGLYTWFYKGRDSIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFH
                     GGSNMADKIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSL
                     INPILNAQNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLL
                     IGGYLYYNLIYTKSEENENE"
     gene            2606..3601
                     /locus_tag="PC503_003254"
     CDS             2606..3601
                     /locus_tag="PC503_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HDF2529212.1"
                     /translation="MKMNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALK
                     FPMKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEDLKLEKNQQK
                     VLENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPK
                     AKDKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKN
                     DYKKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDL
                     ICINIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            3603..4343
                     /gene="cas5b"
                     /locus_tag="PC503_003255"
     CDS             3603..4343
                     /gene="cas5b"
                     /locus_tag="PC503_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF2529213.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYKEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            4367..6925
                     /locus_tag="PC503_003256"
     CDS             4367..6925
                     /locus_tag="PC503_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2529214.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEAYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDDFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALKFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   7050..10116
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7115..7144
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            10201..10695
                     /locus_tag="PC503_003257"
     CDS             10201..10695
                     /locus_tag="PC503_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF2529215.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKTKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
     gene            10730..11728
                     /gene="cas1b"
                     /locus_tag="PC503_003258"
     CDS             10730..11728
                     /gene="cas1b"
                     /locus_tag="PC503_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF2529216.1"
                     /translation="MGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFCLNE
                     VSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRREEIA
                     KSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEGDIW
                     QTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYAKTVTAIYNTHLNQSVS
                     FLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLNDEGK
                     QIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDGL"
     gene            11939..12229
                     /gene="cas2"
                     /locus_tag="PC503_003259"
     CDS             11939..12229
                     /gene="cas2"
                     /locus_tag="PC503_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF2529217.1"
                     /translation="MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRG
                     EITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL"
BASE COUNT         5396 a         1099 c         1905 g         4170 t
ORIGIN      
        1 tatttttttg aaactttgtg attttatttg tcgaataaaa aataaaaaat tttaaaggaa
       61 aaagttaaaa aataaagaat tttataacta taaattatat tttagagttt attgttatta
      121 aatagatgaa aaaatcctaa tatggattat cagaaaatga ggaggttgtt aattgataaa
      181 atgtcttgaa atgtctgtaa aagtgtatct tcttgaaaat atttctttag ataatacatc
      241 aaaagaaata cgtaaattaa tagatgatac attaattata gaagaaaaat ataaggaatt
      301 tcataataaa gctggattta agaattattc ttttaattta ttatacccat tagaaaaaga
      361 taaggtttat aagaaggatt gtatatatac ttttattatt agaactgtag atagtgaatt
      421 aggaatgtat tttatgaata atttaaaaaa tcagcattct gataaaataa aggttattac
      481 aatgagtaaa aaagtgatcc ctaaaaaaca tatagaaagt atttactctg tcactccaat
      541 aatagctaaa tttgaggatg ggtattggag aagtaataaa acagtagaag atttagaaaa
      601 aagaatcaga gaaaatttaa taaaaaaata taatgaattt actaacagta aaatagatga
      661 agattttgaa ttatttcaag ttattaaatt tataaatagg aaacctattt ctactaaata
      721 taagaatata tctttacttg gtgataaaat aagttttaaa gtatcagaaa atgatatggc
      781 tcaggaaatt gcaaattttg cacttggagt tggagtcgga gaaattaatt ctcgtggatt
      841 tggttttgta aactatagat ggttatagga ggtgaaaact tgttaaagga ttgtttagag
      901 atttttgaaa aagaatacaa atctttagga aatagattga taactgatag ctatgtccta
      961 tcctatggaa catatatatt ggtgaaaaat ttttcgaata tagatatatt agaagtttct
     1021 aaaaataatg tggatagtac agaagatata taccataaat tttgtgaact ggattattta
     1081 tcaaaactgg tgtctataga taaatcagtt gattccaaaa aaataataca tagtaataat
     1141 tatctttcat tttttgtaaa aaaggaaaac ttaagacctg ataaaaataa taatgtaaaa
     1201 cttacagaag aaattattga taattattat gatgctttgt taaacccaag aattaaatat
     1261 aaatctgata aaagaaaaaa agaaatctat gattcaatag aaaataaata tggtaaagtg
     1321 gatgaaaata aattaaataa aataagacta tggataaaaa caaatatatt tgatttagtt
     1381 gaatctgtta aaaaagataa aaattattta aaaatatttt ttgatgaaaa aatagagtta
     1441 tacaatgatg aaaaccaaaa atatttatat ccaaatatat ataataaaaa tgatttcaat
     1501 gtaattattg atggtaaaaa ctatgggtta ccaaacgata atatgcaatt aaatgaaaaa
     1561 aagccatttt tgaaattaaa aacaagaatt agaaattcaa ctccttattt gattagtgat
     1621 gatgaagttt tgttacagaa agcttttttt gattatctaa cgaataaagc agcgaatgga
     1681 gaagaagtaa tatatataag tagcgaaaag ggaattcata gaaaaactga tataccaaat
     1741 gaatttagtg gttatatact gagaataaaa aagggtaaag aattagaaat acatgatttt
     1801 gatactgtgg taaatttaaa cactaaaata aaaagaataa atgtagaatg tataatacca
     1861 atagaatatg aaagacataa tttaaaacca aatttagaga taggatatat taataatctt
     1921 ataaaattgg aaaaaacgat tgatactgta ttctttaata aatttatgtg caatagttat
     1981 tttaaagaaa ttaaaaatat aaacttaagt gatttagttc taagggatat acttattaga
     2041 catagagaag gtttatatac ctggttttat aaagggagag atagtatagt aaagcaaact
     2101 ttttcaaact attctatggg tataattgaa aattctataa aaaacaataa ctacataaga
     2161 gcaaaggagc aatataattt aagaatagct ataataaatt attttcatgg aggaagtaat
     2221 atggcagata aaataaaagt tattagtgaa tctttatttg aaaaaataaa ttctataaaa
     2281 acgaaatgta tacaaagtga tgaagaatat tattttgcag ttgggcaatt agcatcgtat
     2341 tttatatcta aaaataagtc aaaaaataaa aatcattctc tgattaatcc tatactaaat
     2401 gcacaaaata gaaaaaaaat catgttagag atagaaaaat tatttaaaaa atataattat
     2461 gatataagtt atgacaacaa taggcgattt aagaatctat attctatgat tgtaggatat
     2521 gaggtagaag aaaaaaaagt taatagagat ttattaattg gtggatatct atattacaat
     2581 ttaatataca caaaaagtga ggagaatgaa aatgaataga agagtatatg gagtattagg
     2641 tataaaatct ataatgtcaa actggaatgc tgatttttct ggatatccaa agacgacatc
     2701 aacaggagaa gtttttggga gtgataaagc acttaagttt cccatgaaaa aaatgtggga
     2761 aaatgaaggt gaaaaagttt tatatgttaa atcattaaaa atagatgaat ctaagaaagg
     2821 agaaataaaa attagaccaa aatcattaaa agagagatat gaagaattgt ttgatataga
     2881 ggacttaaaa ctagaaaaga atcaacaaaa agtactggaa aatctattta aagctattga
     2941 tgttaaaaat tttggtgcaa catttgcaga agaaggaaat aatataggaa ttatgggcgc
     3001 agtacaaatt ggacaaggat ttaataagta tgaagatatt aatgttgaag aacaacaaat
     3061 attatcccca tttagggatc caaaagcaaa agataagaaa aagtcaacaa atgaagaaga
     3121 aaaagaagat gcaaattcaa ctacattagg aaaaaaaata gtaagtgatg aggctcatta
     3181 cttttatcca ttttcaataa atccaaaagc ttatgaagtt tttgttaata tgggtgtgac
     3241 tgatggatat actaaaaatg attataaaaa atttaaagaa gctgctttag taagtgcaac
     3301 tgcattcaat acaaattcaa agcttggttg cgaaaatgaa tttgcattat ttgttgaaac
     3361 tgatgaagag ttatacctac cagatttggc acaatatata acttttgaaa agagagaaaa
     3421 atcaaaagat ttaatttgta taaatataat tcatcttata gcagaattaa aagatgatat
     3481 aaagagcgtt gagatatatt ataacccata taaaatagaa ataaagcctt ttaaagatga
     3541 aatattacct aagatagata aagttaaatt tatgaacata tttacaagaa aagaggtata
     3601 atatggaggt tttgaaattt aacttaagtg gaaaaactgc tttttttaaa aaaccagatg
     3661 taaatagcat aatttatttt acgtatggaa acatacataa aattgcactt atgggtattt
     3721 taggagcttg tttaggactt ggtggatata atcaacagag taaggaagat gagtatccag
     3781 aattctactc tttacttaag gatataaaaa tgtcaatagt tccaaagcat gaatttggat
     3841 atataaataa aaaagtccat atatttaata attctgtagg atatgcatca aaagaagaag
     3901 gtggaaattt aataataaaa gaacagtggc ttgaaaatgt tagttgggat atatatatac
     3961 aattagaaga ttcaactaca agtagagagc ttaaaagaag atttttatct aataaatttg
     4021 tatatatacc ttacttaggc aaaaacgatc atatagctaa tataagtgaa atagagataa
     4081 ttactgattt ttacaaaaca gaagatatta acagagtgga cagtttcttt ataagagagg
     4141 attttgagtt tgaaaaatct tattttgatg ataatgatga ttataaagag ccatttaaat
     4201 atcaggaaaa acttccttat agactgcacc gaatgactaa tcaatatatt ttggaaacta
     4261 tcatatttac taatatgtca gttaaattga ttaataaaaa agaggtatat caagtaaagg
     4321 gtttaaattt aatctttatt taaatttata ggtttaggag aattatatgt actttaaaaa
     4381 agttgagttg tttgatataa gtaataatat aaataattgc aaaaatattt atgctcatat
     4441 aaataaagac aggaagccag aaactttaaa agaacattca gacttatcat actcatatct
     4501 tatgaaatta tgtgtaaaaa aagatttaag ctcttgccta gagagaatag agaataaatt
     4561 ttttaaaaaa gattcttttt taagtaagaa tttttataga gagattatct tgaatatggt
     4621 ttatatgcat gatataggta agattaattc ttcatttcag tttgtaaaaa tgcaaaataa
     4681 aaattttaaa aaaatttcac ttagatatac taaacattct tttatctctt caatgctata
     4741 ttttgattac tattttgaaa agcttaaaaa atatgatttt gaagaaaaaa aaatattgag
     4801 tttatttttg atgataaata catatacaat atcaaaacat catggggttc tgaagtcatt
     4861 taaagaattt ttatttttat ttaaagatga gtttataaac attaaagaaa attttaaaga
     4921 tttatttaaa aacaattata atttagagct taaatcagtt cccaaaacta tagaaaaaat
     4981 ggtaagaggt gtagaagcgt atttagatga tagccatata aaggataact tagctataga
     5041 cttatatata tattcaaaat tgatgttttc aattgttaca tcttgtgatt tttatgctac
     5101 atcagaatat aatagtggta attctataga tgattttggg acaattgata attataataa
     5161 gtattatgat gtattaaaaa aatctgaaat atataagggg atgaaaaaat atagggaata
     5221 cttaaataac aatagtgaat gcccatataa agagaatgat ataaacagat tgagaacaga
     5281 aatgagtata gaagctgaag atgcaattac acataatacg agaaaaagaa tattttattt
     5341 agaagcacca actggaagtg gaaaaactgt tacatctata aatctagcac tgaaatctat
     5401 agagttaaat caatctttaa aaaagatatt ttatatattt ccatttaaca cattagtaga
     5461 gcaaacaaaa gatgtattta taaatgaaat atttaattct gttaaagaca tacaaaaaga
     5521 tgttgtagtt ataaattcaa taacaccaat acaaacagaa gataaagaag aagataataa
     5581 aaatgttgaa tattgtgtta ctaaacaaga aattgattat gataaatcat tgttaaatag
     5641 acaattttta cactatccta tagtacttac aactaatata ggttttttta actatttgtt
     5701 tggtgtatca agagaagaat gttttccatt gatacatatg ataaatagtg taattatatt
     5761 agatgaaata caaaattata aaaatgagat atggaaagaa attattttgt ttttagaaaa
     5821 atatgcagat atattaaata taaaatttat tataatgtct gcaactttac ctagattaaa
     5881 taaattagga tgtaatgatg ataattttgc atatctagta aaaaacagag aaaaattttt
     5941 taaaaatcac ctttttaaag atagagtaaa cataagtttt gagatgttaa attcagaaat
     6001 taatgatatt gaagaaatat cagaaaaggt tatagaagaa gcagaaatat ataataagat
     6061 actgatagag tttataaaga aatcatcagc actaaaattt tataaaaata ttaaagaaaa
     6121 attgaagtat aagttagaag atgttttttt attaacaggt gatgataata aattagaaag
     6181 aaaaaaaata ataaataaaa ttaaagatat gaactctgta attttggttg ctacacaagt
     6241 tgtagaggct ggagtagata tagatatgga tttgggattt aaagatatat ctacaattga
     6301 ttctgatgaa caatttttgg gaagaataaa tagatcttgt aaaaaattaa attcaaaagt
     6361 atactttttt aatttagatg atgcaagtaa gatatataag aaagatgtta gaaaagagag
     6421 acatttaact cttaatgagg aaagtaatag aaaaattatt ttagataaag actttgaaaa
     6481 gtattatgat aaaataatag ccagaataga agaaaataag cataaacata atgacaagaa
     6541 tatagaggtt tttataaaag atattgtggg aaatttgaat tttacagagg taaaaaaatg
     6601 gatggcttta ataccagatt taaaagagta tacaatcttt ttaaatacta tagttaaaga
     6661 tgaatctgga aatatgattg taggaagtga tgtatggtat gaatatatat cactactaaa
     6721 aaatgataat gttgagtatt ctgaaaagag ggtgaaaatg tctgaaatta tggaaaaact
     6781 agattatttt acgtataaag ttcagaaatt tgataattca tttaatgatt tagttggaga
     6841 tattttttat attgatgatg gaagtaagta ttttacagag ggaaagtttg atagaagtaa
     6901 atttaatcaa aatgaatttc tataatgtat ttagattata tagagaatat ttatcccaag
     6961 ttaattaatt agaattagtt taaaactatt gaaatataga tattttatag cttatatatt
     7021 ttttctagga ttagctggga taaaaaatct gtatattagt gttttcagtg tatttaaggg
     7081 gattatattt ttaagaagta ctgattttaa agtggttaaa cagtaacatg agatgtattt
     7141 aaatttttac tacataatta aatcgtagtc aataccgtac aggttaaaca gtaacatgag
     7201 atgtatttaa atctctgaat agccaatcaa ctttgctgca ttactcttgt taaacagtaa
     7261 catgagatgt atttaaatga taatagttat atatattttt tacaatatat tattgttaaa
     7321 cagtaacatg agatgtattt aaatttactt ctcctgtttt gaaatctata tattcatcat
     7381 gttaaacagt aacatgagat gtatttaaat ataatattga tacaaatatt ttgggtaaat
     7441 ggacttgtta aacagtaaca tgagatgtat ttaaattcga tatggtaaca aatttataaa
     7501 agatatagaa tgggttaaac agtaacatga gatgtattta aataaagaaa aacgaaattg
     7561 gtgattttga agcaatgtgt taaacagtaa catgagatgt atttaaatta gtaactacaa
     7621 tgcttttcct tttgaagatg atatgttaaa cagtaacatg agatgtattt aaattaataa
     7681 tgcacctatt ttaacagtac ctggtctaaa gttaaacagt aacatgagat gtatttaaat
     7741 tcaagtctag gagacaacat aaatagtaca gatgggttaa acagtaacat gagatgtatt
     7801 taaattagta aaaccagatg gaactgttgt aataccacca aagttaaaca gtaacatgag
     7861 atgtatttaa atttaaaaac atcttgagga atatctttaa cagtaattgt taaacagtaa
     7921 catgagatgt atttaaatgc attttcaggt gcatgataaa taggtaaatt agatgttaaa
     7981 cagtaacatg agatgtattt aaattttttg taattagcca gattatcaac tcccaaaata
     8041 gttaaacagt aacatgagat gtatttaaat taaatatcgt ccttcgtagt caaagcaaca
     8101 ccagaaggtt aaacagtaac atgagatgta tttaaatcgt aaacaaaatt tatcaagaga
     8161 agaatttcta aggttaaaca gtaacatgag atgtatttaa atttatattt gataagagta
     8221 tcaaatcgac ttaaaatagt taaacagtaa catgagatgt atttaaattc aatcttaata
     8281 cacagacatt tttaaaaaca aaacgttaaa cagtaacatg agatgtattt aaataaatag
     8341 acaaatattg aatagctctg tcttcatcaa gttaaacagt aacatgagat gtatttaaat
     8401 atatttacaa aatctctaac atatttttta acttctgtta aacagtaaca tgagatgtat
     8461 ttaaattctt ttaaagagtc ctcgggagcc tcgaaaactt cagttaaaca gtaacatgag
     8521 atgtatttaa attactcaaa taaatttcta atttgtttat ctactaacgt taaacagtaa
     8581 catgagatgt atttaaatta gaatttacaa caatataagc ctctttaacc ataagttaaa
     8641 cagtaacatg agatgtattt aaatatgttt ttagtagtac atttaataaa actttttaaa
     8701 gttaaacagt aacatgagat gtatttaaat gaaggaaccg taccttgata aatcacgacc
     8761 gtacccgtta aacagtaaca tgagatgtat ttaaattgta tatttgatgt tgttatttct
     8821 cctgtgtata atgttaaaca gtaacatgag atgtatttaa atgaagttcc acccccacca
     8881 cccccactac tttgagaagt taaacagtaa catgagatgt atttaaatta acaatagagt
     8941 aaatataata aacaagcata caaagttaaa cagtaacatg agatgtattt aaatcccctt
     9001 ttgcatggta ctagacacgc atatatggtg gttaaacagt aacatgagat gtatttaaat
     9061 acgcctatat gcggagtaac agatttttgc ctggatggtt aaacagtaac atgagatgta
     9121 tttaaatact gttttgggat agactggaat taaatggtct gtgttaaaca gtaacatgag
     9181 atgtatttaa atttttggaa tgaagcatca acagataata aagaaaaagt taaacagtaa
     9241 catgagatgt atttaaatca aggaaacaaa agagaagtga aaagaaatat aatgttaaac
     9301 agtaacatga gatgtattta aataatcttt taaatggaaa ttaagtaata aaagagaggg
     9361 ttaaacagta acatgagatg tatttaaatt caattaaata agcattaatc ttagtaaaat
     9421 caaacgttaa acagtaacat gagatgtatt taaattttct tgtgttaatt gaacccccat
     9481 tttaagctcc agttaaacag taacatgaga tgtatttaaa tcagaataca gcttctatat
     9541 ctggatacat ttgtcttggt taaacagtaa catgagatgt atttaaatgt gaaaagtaat
     9601 acaggtatag agtctaaacg ctcggttaaa cagtaacatg agatgtattt aaatcaatgt
     9661 atcctctttt ttagttttgg agcctctttt gttaaacagt aacatgagat gtatttaaat
     9721 tagttagcac attttatttc aagccttaaa acattcgtta aacagtaaca tgagatgtat
     9781 ttaaattaat ttgcacactt aacctctaat cttaaagtat tagttaaaca gtaacatgag
     9841 atgtatttaa ataacacaat attatcttta atagaattaa acaaatgagt taaacagtaa
     9901 catgagatgt atttaaattt ttgttggtct tgtgcttctt ttaaaagctg attagttaaa
     9961 cagtaacatg agatgtattt aaatttaaaa agttctgtta ttaaaacatc caaaccaatc
    10021 gttaaacagt aacatgagat gtatttaaat tctgtaccat ctagccaaac cgtttttgaa
    10081 gttaaagtta aacagtaaca taagatgtat ctaaattact ctatcataaa attttaatat
    10141 attaaacaaa ctaatatgtg atatacttat gtataaataa caaaataaat aggtgatgtt
    10201 atgaaaatta caggaacttt gataaattac tatttccatt gtaaaagaca atgctggttg
    10261 cttggtaata gaataaattt ggaagaaaat agtgaagatg taaaaatagg tagacttctt
    10321 catgaactaa aagaagaaaa aacaaaatat aaagaaattg caattgaaaa tataaaaata
    10381 gacaaattaa caagagaata tttagtagag gttaaaaagt ctgatgctga tatagaagct
    10441 gttaagtggc aagttctttt atatttaaaa aagttaaaag aaaagggaat tgtaagaaaa
    10501 gggaaaattg aatttataga aaaaaataaa actaataaaa aaatagtctt tgtagatttg
    10561 agtgaagtat ctgaagaaca gcttatatct atagaaagag aaattgttaa tttaataaat
    10621 agtgataaag caccatgtcc tgatttaaaa aaaggatgta aaaaatgtgc ctattatgaa
    10681 tattgttata tataaagagg tataagaaac atataaggag gtgttaatat tgggaaagac
    10741 aaaatatatt acctcaatgg gtgaactcac aagaaaagat aattctatat gttttagaaa
    10801 aaatggaagg aatgtatata taccagtaga aaatactagt gaaatattct gtctaaatga
    10861 ggtatcttta aattcaaaat tactggattt tttatcaaga gcaaatattg ttgttcattt
    10921 ttttaattac tatggtggat atagtggaac tttttatcct aaagaatatt taataagtgg
    10981 aaaagtaaca gtggcacagg taaaaacctt tgaagataga agagaagaaa tagcaaaatc
    11041 catagtcaat ggtataagga ttaatgcaat aaatacatta tcgcattact ataagcatgg
    11101 aaattcagaa atacaaccat tattatcaca tctaaaaaaa gattctataa acaagttaga
    11161 aaaatcaaat aatataaaag aaatattatc agtcgaagga gatatttggc aaacatttta
    11221 tacttccttt aagtatattt taagagagga atttattttt aataaaagag ttaagagacc
    11281 accagataat cccttaaacg caatgatatc atttggtaac agtattttat atgctaaaac
    11341 tgtaactgct atatataata cacatctaaa tcaaagtgta agttttttac atgaaccaag
    11401 tgaaagtaga ttttctttaa gtctagattt aagtgaaaat tttaaacatg ttataacttt
    11461 taaaactata tttgatttag ttaataatag aaaaataaat attgaaaaac attttgataa
    11521 aaatttgaac tactgtgttc taaatgatga aggaaagcaa atttttataa attctttaga
    11581 agaaagatta gaatcagtca aagaacatcc aaaattaaaa cgaaaagtaa gtttaaaaac
    11641 ctgtataaaa ttagatgctt acaaaatgtt aaagtgtata atggaagaaa aaagttttat
    11701 tccatataac ataaaagacg gattataatt taaacataaa gtaagtattt taatatagaa
    11761 ctttgatata tataagaatg ataattatgc tattataagt atacataata tattattgaa
    11821 ataatataag tttttagaag tattttaaga tgagaaagga gaaaatactg aaaaataatt
    11881 attctattat aatttgccaa ggttttgtat atttttcagt ttaaatatta tattacatat
    11941 gaaaaagaaa aacaatttaa attataatta tgtatttgta gtctatgatg taggagaaaa
    12001 aagagtaagt aaagttttta aagtgtgtaa aaaatatctc tcgcattttc aaaaatcagt
    12061 ttttagaggt gaaataactc catctaagat tatgagctta aaacgtgatt tagaaaatat
    12121 tatagataaa gataatgatt ttgtatgtat aataaagttg atgaattcta atacatttga
    12181 agaagaaata ttagggaata atagtaattg tgaaaatatg atattataaa tctaattact
    12241 atatttgtaa aaaataatag cttattaaag agtagtaaaa ttgggatata atttatgata
    12301 gagactgcaa gtagattttt gtgaaaagga tttacttgca gtatttttgt tatgtataac
    12361 tgttaacatt agtgtacaaa acattatcaa tagcattttt ctataatgaa gaaatactat
    12421 tataatggga aaattttatt aatactaggt aataatatat ttacacaagt ctatatatat
    12481 tataattttc attataatta ttcagtattt ctaataataa gattcttttt gtatttattt
    12541 aatatgattt tatcaagaat aaaagattaa
//
LOCUS       DAMJWC010000095        11991 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMJWC010000095 DAMJWC010000000
VERSION     DAMJWC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11991
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.099"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            145..1344
                     /locus_tag="PC503_003260"
     CDS             145..1344
                     /locus_tag="PC503_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF2529218.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1396..1899
                     /locus_tag="PC503_003261"
     CDS             1396..1899
                     /locus_tag="PC503_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2529219.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            2006..2323
                     /locus_tag="PC503_003262"
     CDS             2006..2323
                     /locus_tag="PC503_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529220.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            2481..3440
                     /locus_tag="PC503_003263"
     CDS             2481..3440
                     /locus_tag="PC503_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2529221.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            3555..4340
                     /locus_tag="PC503_003264"
     CDS             3555..4340
                     /locus_tag="PC503_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529222.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            4632..5951
                     /locus_tag="PC503_003265"
     CDS             4632..5951
                     /locus_tag="PC503_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2529223.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6026..6454)
                     /locus_tag="PC503_003266"
     CDS             complement(6026..6454)
                     /locus_tag="PC503_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529224.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(6545..7921)
                     /gene="hydG"
                     /locus_tag="PC503_003267"
     CDS             complement(6545..7921)
                     /gene="hydG"
                     /locus_tag="PC503_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF2529225.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(7922..9007)
                     /gene="hydE"
                     /locus_tag="PC503_003268"
     CDS             complement(7922..9007)
                     /gene="hydE"
                     /locus_tag="PC503_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF2529226.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(9043..10251)
                     /gene="hydF"
                     /locus_tag="PC503_003269"
     CDS             complement(9043..10251)
                     /gene="hydF"
                     /locus_tag="PC503_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF2529227.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTQKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(10266..10517)
                     /locus_tag="PC503_003270"
     CDS             complement(10266..10517)
                     /locus_tag="PC503_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF2529228.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(10898..11938)
                     /locus_tag="PC503_003271"
     CDS             complement(10898..11938)
                     /locus_tag="PC503_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF2529229.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLSLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         4391 a         1494 c         1817 g         4289 t
ORIGIN      
        1 atatctatat gttaaaatat agtagaagat gttagtaaat aataggatga gttctatttt
       61 aatacaatta aattaagctt agtttgaaat ttgtatctaa aaagtaaagt aatctagaat
      121 taagaaaatg gagatagaat tataatggaa aaattatatt atacaaatca gtatataaga
      181 gattttacag cagaaataat tgaaataaaa gaagtagaaa ataagtatca tgttttatta
      241 gataagacag ctttttttcc tggtggagga ggtcagtttg gagacctggg aaaaatagag
      301 aatgatgatg taataaatgt gtatgaagat ggaaaaaaaa tataccatgt attagataaa
      361 aaacctataa agatacataa ggtaaagtgt agtattgatt gggatagaag agaagatgga
      421 atgcatcaac attttggaca acatgtattg tctggatgtt tttttaaaac ttttaatgca
      481 aatacgacag gttttcattt gggaaatgag tatagtacag tagatataga aggtaattta
      541 gaagaggata aaattagaga gatagagttg tttgccaatg aaattattcg tcaaaatata
      601 caagtagaga cattacttcc aacgaaaaaa gaactaaaaa agatttggtt aagacgtgat
      661 ttgccaaata ctgatgaaga gataagagta ataaaaatag gtgatttaga tacgaatgca
      721 tgttgtggag tgcatccaaa atcaactggt gaattgagaa tgataaaaat aaagaaatgg
      781 gaaaaacata agtcaagtac aagaatagag tttctagcag gtaaaagggc agtggatgaa
      841 gtattgaaga gggatatata tttgactaaa atatgtagat atttaagctg tagtgaggaa
      901 gatgctataa atggtattgt aaatctaaat agtaaagtgg aagaggcttt aattaaaaaa
      961 agaaggcttg aagaagtagt atctacatat caggtcaaag aaatgattga aaaagcaaat
     1021 aaggttggca atatttcggt cattaaaaaa atttatgatg atgaagattt gaaatatgta
     1081 aataagatag caaataaaat tgcagaatat gaaaatagta ttgcattatt agctgttaaa
     1141 tttaatgata aaataaattt agtttttgca tgttctaaaa atttaaaaga tattaatatg
     1201 ggagttttat taaaggatgc aataaatctt atagatggca agggtggtgg aagtaaagta
     1261 ttagctcaag gaggaggtaa gaataatgga aatttagagg ctacacttga ttatgcattt
     1321 atgaagatag aaaaaactct ataaatatat tatataaaaa accttagtag ataaaataga
     1381 tatggaggaa taagtatgga gcaacaaaag gactacatag agttatatga aaatgaagaa
     1441 ctaatagaga taagagaagc acgtatggat gatttggata caatagcaaa atttaattat
     1501 aatttggcta aagaaactga aggaaaagaa cttgatatgg atgttttaac taaaggtgta
     1561 aaagcattgt tattagatga gagaaaagga aaatatcatg tatatacagt atttgataaa
     1621 gttgttgcac agattatgta tacatatgag tggagtgatt ggagaaatgg aaatttcctt
     1681 tggattcaga gtgtatatgt agataaggaa tatagaagaa aaggtatctt taattattta
     1741 tttaattata taaaaaatat atgtgataaa gatgaaaata tagttggaat gagattatat
     1801 gtagaaaaag aaaacataaa tgcaaaagca acatatgagt ctttaaatat gtatgagtgt
     1861 gattataata tgtatgaata cgaagtagta cattcgtaat ataaatttgt aatactgtta
     1921 tactgatgtt ataaagtatt gattatattg acgattatat gaaataaact ggatattata
     1981 attagaattt ttagggggta taaaaatggg cgttttaaaa ggaatgtttt atgtattttt
     2041 atttttagat ttagtgtcaa tattctgttt ctttttcaat aaaggaaaaa tagcatctaa
     2101 taaaattgtg tttaatgcaa taggagtact tacatttgta ctttgtttta tgctttttag
     2161 ttattatcct aataataatc ttattggaaa atttattgct tctctatttt ttatatttgg
     2221 agttgcagga gttatgttga aagaaaaaaa ttttttatat gctagacttc ttttaactgt
     2281 agttatagtt ttttctacat taagattgtt cgttattcaa taaaatgtat ttgtataaaa
     2341 atttattaaa gtctacacat ttaagtgtag gcttttttga ttttttgttt gaaaattaag
     2401 gaaattttaa ggaaatttta aaatcgtctt aaatatttat tgatatactt aaaatattaa
     2461 tagcgaaagg agacttatca gtgatagaaa gtaaaaagtc agaaaaattg ttactgtcaa
     2521 ttatatacat aatatttttg gtatatattt taatgattat aagaataatt ttatttagag
     2581 atgtaccaat ttacgctatt ttcaagggaa cgtttaggaa tgtaaattta attccatttt
     2641 atacaatata tcaatttata gtagatagta atcttgactt tatgaaagct actgtaaata
     2701 ttatagaaaa tataggtata tttattccta tgggaatttt tttacctata gtatgtaaaa
     2761 atctaaataa aaaaactata attatagtaa ttatacttgt tagcctagca tttgaattaa
     2821 cacaatatat ttttgctctt ggaagtagtg atatagatga tgttatttta aattcattag
     2881 gtggcataat tggaattaat atttacataa acatgaataa attatttccc aatgatatta
     2941 acagatttaa ggctataata ggtactagtt tagttttagg agttatagga ttaggagtta
     3001 tttctaaaaa ttatcataac ttactaactt ttaaatttag acctgataga aaaatatcaa
     3061 aaatattaat tgaagaaaat agggaaataa ttaaagatat aaataaagat acagtagata
     3121 tagttgggac atttgagagc tttaaaaaag gaataataac tattaaagca ggttctaata
     3181 acaaagtaaa gagaccagag aatttaattg attctgatgg aaatataaga atttatttaa
     3241 atgaaaatac aaaattagta tcttatataa ttaccaaaga atcaaaaatg gatatagtta
     3301 aatatgagga atttgatgtg aagaatttag atttattaag gagatatgat actattaatg
     3361 tttggattga taaagaaaat cagccaaagg ataaacatgg tattatggct agtaaattat
     3421 taattggatt gtatgaataa aatattaaac aagaataaaa gaataacaaa tataaaaaac
     3481 gaaaaaacta tttctataat tatttttacg ttgtgcataa aataagaaca ttagtgaagg
     3541 agtagagata aattatggag ataataaaat atatcttgta cttttttata tattcatttt
     3601 taggatggac agtagaaagt ataggatgtt ctatagcaag caaaagaata atcaacagag
     3661 gttttttaaa tggtccaata tgtcctgttt atggttttgg agcggtaatt gtgatatcac
     3721 tattgggaag atttaataat gtagtaatag tatttctatt aggaatgatt ttaactacga
     3781 tactagaata ttttacagga tttattttag aaaccttatt tcatgctaaa tggtgggatt
     3841 attctgacag aaaattcaat ataaagggta gagtatgttt aaaaaatgca atatactttg
     3901 gtgtaatgtc tgttttaata ataagattta tacatccatt tataaaatat tttgtaagta
     3961 taattccata tagaatatta atttcaatgg ctataattac aacactttgg actatacttg
     4021 atttgattgt tactattata acacttaaaa aattagatat aaagttaaac ttactagacg
     4081 atataattac agaccttaat gatataaatg tgaaattgga taaatttgat agaggagaaa
     4141 tacaagcttt atttaaaaca ataaataacg acgaattaga agttagagaa aaaataaaca
     4201 aaataaatag taagttggac cgtatagagt ctaatattat tttacaaaaa agagttataa
     4261 aagcttttcc acatataaaa cataaaaaac aacaagagca actagaacat tttaaaaaaa
     4321 ttattaatga gaaaaggtaa ttatacaatt taatgaagac gaatagaata atggtattta
     4381 taagatgatt ttcagaggac tctataaaaa tagaatagag tcctttattt tttgaaaaat
     4441 aatgtttatt tgataaaaat aaaatatatt gtttctgaat aacaaatatt ttgaaaatta
     4501 taaaaacata tattgacaat ttgtgtcaaa aatactaaca ttaagtatat aaagaatttt
     4561 atatgagaat atctttataa atcgcaataa ttttaaaaca taaatttatt taaagagggg
     4621 atgatttgcc aatgagcgag ataactagtc aaatgataag tacagaagaa aaaaaatatg
     4681 ttgctaaaac tcaaaagata ccttattatc cagtagcatt taaatcaggt gatggtgcaa
     4741 tgctatatga ttatgaaggt aatgaatatg tagatttttt agcaagtgca ggctctgcaa
     4801 atgtaggtca tggtaataag gaaatctcac aagcagttaa agaacaaatg gatgatataa
     4861 cacaatatac acttgcatat ttccatagtg atcctcctgt aaaattagct gagaagcttg
     4921 tggaaatagc ccctggagat aatgataaaa aagtactata cagtgcaact ggttctgctt
     4981 gtatagatgc tgctataaaa ttagcaagag gatatactgg aagaacaaag ataatatcta
     5041 tgtgtgaatc ttatcatgga agtacttatg gagctatatc tatatctgct ttaagtacaa
     5101 atatgagaag aaaaatgggt ccattgttac cagaagttta tcacttccat tatcctgata
     5161 aaaatagaac agctaaagaa tgtttagatg agatagaata tgcttttgca cactatctac
     5221 cagcagaaga ggtagctgca atatttatag agccaattgc aggagatgca ggaataatag
     5281 tgcctccagt agagtgggta caaggtttaa gtaaaatatg taaagaaaat ggaatattac
     5341 ttgtaagtga tgaaatacaa caaggtatgg gaagaacagg taagtggttt ggtatagaaa
     5401 attttggtgt tgaagcagac cttatagttc ttggaaaatc tgttggaggt ggattacctc
     5461 taggagcagt tgttggaaga acagaaataa tgcaaagtct tgatgcacca gcacatttat
     5521 ttactttagc tggaaacaca acagtatgtg tggctgcttt aaaatctata gagataattg
     5581 aaaaagaaaa cttacttcaa aagagtatag aaatgggaga ttatattaaa gcaggatttg
     5641 aaaaactaaa agaaaaatac gatataattg gagaaataag aggcatagga ttatctatag
     5701 gagttgatat agttaaagga aaaggttcta atgaaaaaca tccagatgct acagctaaga
     5761 tatgttatag atgtatacaa actggattaa taatgatatt cttaggacaa tctactttaa
     5821 gagtgcaacc acctctagta ataactaagg agcaagtaga taaagcaatg aacatcatag
     5881 attctgcaat agatgattat ttaaatggta gaattggtga tgaagtatat gaagtaactc
     5941 aaggttggta aaataaatat taaatgaaaa taggagttat ctcaatttta gaaaattatt
     6001 tctgaaatga gataactctt ttaagttacc cacaaataag aaaattgttt gattcattaa
     6061 agactatatt tcggatgtcg tttttgtgag tatcagagac agtattacga gaataattac
     6121 ctttattcgt actatctgtt aatttagtta taattaagat agctaaaaga ataagaatta
     6181 ctgtgtataa agcaataaca tatggttttc ttttatattt gtatttgtta ttgaaaaaag
     6241 aatggccata attattttta tttactttag atgtatttgt attctttttc ttgttacctt
     6301 tctttttatc atcctttttt ctatttttag ggtaaggaat gactttgtgt gtattatcaa
     6361 gtttgatatt tttatttttt tgaatattgt tttccaggct agcctttttt tctccaaatt
     6421 gaatagtttt attggtattg ttgttatctt tcaatgttaa tctccctccc ttaaactttc
     6481 cctttagata atattactac taacctatgg aatatacaat aaataatata taagtaataa
     6541 aattttatag gtataaatct ctttctccac gctctaaggc agtcatattg ttagatacta
     6601 tgtttcttat atcttctctt tctatcttac ctatttcttc tgcgataagt tttttaccca
     6661 taattttaag ttcttcatct ccataatcga ttaaaaattc atttaatgta gtaagagcat
     6721 ttggtgtaca tacattatgg atttgtcgac ttttagctaa gctcatgaat ctatcgccag
     6781 ttctaccttt acgataacaa gctgtacaat aactaggtat atatccatca gtaatcagtt
     6841 ctttaagcac ctcaacaggg cttctatggt ctccaacttc aaattgttct gtattgtcac
     6901 catcttcata tgctttatat cctccaacac ctgttagaga acctgcacta atttgtgata
     6961 caccatattt tagtaactca tttctcattt cagcagtttc tctagtggac attatgattc
     7021 cagtaaaagg aacagccaat ctagttatag ctactatttt tttgaacata tcgtcagaaa
     7081 ctaagtgagg aaaatcttct aagctcatac cttcagcttt tttcaatcta gggaaagata
     7141 tagtatggaa acctacacca aatttttcct ctaagtgttc gttgtgcatc ataagtccta
     7201 gaacttcaaa tttagggtca gataaaccaa ataaaactcc tgcaccaaca tcatcaacac
     7261 cagcttccat agctctatca aaagctgtta aatggtaata atagtcattt tttatagatt
     7321 gaccatgcat ttttataaat gttggtttgt gataagtttc ttggaataat atataagttc
     7381 ctattccttt ttcttttagt aatttatact catctacact tgtagctgct atgttaacgt
     7441 ttacccttct tatatttccg ttttcattat atgttgaata aattgcatct aagcaatcta
     7501 agatgtaatt tatatcacaa tttttagggt cttcaccagc ttctagagca agtcttttat
     7561 gacccatttt ttctaatatt ttaacctctt cctttatctc ttccatggta agtttttttc
     7621 ttttaaattt gttgcattta ctaaaaccgc aataaacaca ttcatttaca cagtagtttg
     7681 atacataaag aggggcaaat aaaaccactc tattaccata tatttcattt tttatttgcc
     7741 cagctatact aaataatcta tctagttgtt ttttatcttc tacttcaaga agtgtagcta
     7801 tatctttata actaagtttt tcccttctat cagccttatc aagtaccttt tcaatatcat
     7861 cagaagttga attttttgca tcttctaata aagaattaat aagttcatgg tttatgaaca
     7921 tttacaaacg cctccattca atattatcac cgcgagaata gtcaacttca agtcctaatg
     7981 acttgatgtt ttcttctaaa ctttggtgat attcacaagc ttcttgacca gtaaaggctt
     8041 tgttatcgta aagagaatat tgttttctaa attcttgagg agaaaggttt ggcataatta
     8101 cattgcaacc agctaaaaga cctgcatttc taccactagg gtttatagat gccaaggctg
     8161 ttgtagcggg taataaaact tttggaagta gaagtcttgt aattgaaagc ataagtaatg
     8221 tcttctctaa atctccatgt ttataatcct taaaaattgt atcatggtgt ggaataaaag
     8281 gtcctattcc aaccatatga ggatttaact cttttaggta taataaatca cgaacaaggt
     8341 cttcgttgtt ctgaaatggt gattcaacca taaatccagc acctacctga taaccaattt
     8401 ctttaaggtt ttttaggcat tcttttctag ttctaagctc aatgtttggc ggatgtaatt
     8461 ttttataatg actgtctgta gcagtttcat gtcttaaaag atatctatct gcaccacata
     8521 aaaagtattt tttatacgaa tcataactct tttctcctag tgatagagtt atggcacaat
     8581 cctcatattt attttttata cttgaaacaa tttcacatat tttatcatca gtaaaatatg
     8641 catcttcacc accttgcaaa acgaatgttc tgtatcctat tttataacct atatcacaac
     8701 attcaagtat ttcatcaagt gaaagcctgt atcttatgat atttttatta gaagattgta
     8761 ttccacaata gtagcaatta tttttacaat agtttgtaag ctctataagt cctctcaagt
     8821 agactctatt tccataatgt ttatttctca tgtcgctagc ttgtttataa agatagtttc
     8881 ttaaattttg ttcgaagtta tattcctcat tgtcgatatt ttctattaaa tatagtagtt
     8941 catcaaaact taatgaatta atgctgtaaa gtttatctat aaagtattta atcttatttt
     9001 tagtcatatt caaatatgta attattaagt atagttaaat ttttaataat tgaaaagttc
     9061 aagtgatctt tccaaaatac cttttacata tgctattaag acaccatagt ttacaatagg
     9121 tacattgaaa gattttgcct tttctattct agataacatt ccagctctat tcatcataca
     9181 agctccacag tgaactacaa gggcatattt atttatatct tcagtgaagg atactccaga
     9241 actaaattca aaagtaatgt ttttgccagt tttctttcta atcatattag gaatttttac
     9301 tgttccaata tcatcagttt gtctatgatg ggtacatcct tcggccatca agattttatc
     9361 accatctttt aaattttcta aagcataagc tccattaatc aattctttaa ggtctccctt
     9421 ttgtctagca aacaatatag aaaaagatgt aagaggaata tctttttgtg tatctttatc
     9481 tacttgtgga aatacttgag agtcagtaat aacaagtttt ggttttttgc ctaaattaga
     9541 tagagtttct tttaaactat cttcttttgt aactatagaa attgcaccat tatccaaaat
     9601 atctcttata acttgctgtt gaggaagtat aagtctacct tttggagctg ctttatctat
     9661 tggaacaact aaaacaacta aatcatttgg ttcaattaaa tctgatacca atttgaactc
     9721 agtgctatcc ttaggcaaaa cttttattat ttcatttttt aaattttcaa ttccaatttt
     9781 atctgttgat gagacagaaa caactggaca tttaacttta tttttagtta agtttaaaat
     9841 ttctgattga ttcttaatag tatcaatttt gttaagaatt agaatatgag ggatattctt
     9901 atcattaaat ttttcaatta gtgacaaatc ttcttgtgat ataccaattt ggcaatccac
     9961 tactagtaaa gctatatctg tcttttctaa aacatctagt gatttaccta ttctaagttc
    10021 accaagttca ccaacatcat caagaccagc agtatctata agaacacaag gtcctatagg
    10081 aaggatttcc attggtctaa atactgggtc tgtagtagtt ccagcaatat ctgagactat
    10141 tgcagcactt tgatttgtta tagcatttat tatgctagat ttacctgcat ttcttttacc
    10201 aaagagacct atatgtactc ttaccgattg tggagtagaa tttagactca tttgtactca
    10261 ccaccttaaa cttctttttt tgatatacta gtttttacag atacatgagg tatgttgccc
    10321 aatttaccag tcaaactatt aatagtgtcc atttcgccaa caactgctat acatacgatt
    10381 gagacacctt cttcttcgca aggaatgccc attcttcctt taataatacc tttaaaacct
    10441 gatacaacct cattgaattt aaattgacat tcttttggtt cttccaaaat agcacttata
    10501 actgcaacct ttttcataaa tatcctccta actcagaaaa tatgtcttaa acaaatccaa
    10561 aatcaaaaaa cttttctttg taaagaaaag tttctacaaa agaaaagtta ttaattacac
    10621 aagtataatg tgctatatta aactatttcc ttacagatta gataactctt ttctggtagg
    10681 gttagcttgt aaaaatttaa tttaacaaca agtaactgaa gaaaattttt atacaattta
    10741 tataaattat aataaaaatt aactaaagaa aattgaagtt acttatataa tagtagtaaa
    10801 ttgaaattaa gtctatagaa aaaccaattt ttgtataaaa ataaaaatta aagttaatta
    10861 tttgttaaga attgactttg gtaaaatata taattaatta ttctttaagc atataattta
    10921 taagtaattt tagtgtattt tcaatagctt ctatatgtgt tctttcataa tggtgactat
    10981 tgtttgttcc aggaccaaca catgctattt gaacatcttc tccccaacga atagcttctg
    11041 aagcatctga accatagaaa gtaaatacat cgacagcgta gtctaaatta ttgtcttctg
    11101 caacatcgac aagcttgttt cttaaattaa aatcatataa tgataaatta tcttttgcaa
    11161 ctatagttac accatgttca ctagatgttt gacttggtcc agtaggtgct atatctattg
    11221 ctacaaattc ttttgttttt tcaggtaaac atttagaaac accatgtcca atttcttcat
    11281 aattacttat ataaaagtta gtagtatgct taggtgttaa attgttttct ttaaaatatc
    11341 tacatatttc aagaaccatt gctacagctg atttattatc tatatatcta gattttataa
    11401 aaccagattc tgtagcctca aatctatggt ctaggcatac aaaatcccca acacttattc
    11461 ctaaatctaa tacatcttgc tttgtaaata ctttttcatc aagtctaata atcattgttt
    11521 cttcatttct ttcagtggca gcttttgttt gaccatatat atgagtagaa gcatacttaa
    11581 atacaacact tcctctgatt tttttacctt ttctagttat aacagtacag ttttctccct
    11641 ctatagccgc ccaacatcca ccaccaactt tatggtattt aagagtacca tcagatgata
    11701 tttcttttac tatagctcca agtgtatcca tatgtgcaga tattgttatt tgatttgaat
    11761 catcttcacc aggaagagta gctataagtg cacctttttt tgtaagaata gtgtcaagac
    11821 ttaaattttc aaaatctttt ttgatttcta aaactgcatt ttcagtatat ccagctgggc
    11881 ttggaatgtc caaatatttt ttcattaaat ttatagtatt agttaaattt aaattcatat
    11941 tgtttcctcc taaataaata tatttataca aattataaca taaatacaaa t
//
LOCUS       DAMJWC010000096        11950 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMJWC010000096 DAMJWC010000000
VERSION     DAMJWC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.100"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            291..473
                     /locus_tag="PC503_003272"
     CDS             291..473
                     /locus_tag="PC503_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529230.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1300..2214
                     /locus_tag="PC503_003273"
     CDS             1300..2214
                     /locus_tag="PC503_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF2529231.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2604..3251
                     /locus_tag="PC503_003274"
     CDS             2604..3251
                     /locus_tag="PC503_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2529232.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3418..3987)
                     /locus_tag="PC503_003275"
     CDS             complement(3418..3987)
                     /locus_tag="PC503_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529233.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3992..4891)
                     /locus_tag="PC503_003276"
     CDS             complement(3992..4891)
                     /locus_tag="PC503_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2529234.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIIFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4902..5051)
                     /locus_tag="PC503_003277"
     CDS             complement(4902..5051)
                     /locus_tag="PC503_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529235.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(5044..5628)
                     /locus_tag="PC503_003278"
     CDS             complement(5044..5628)
                     /locus_tag="PC503_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2529236.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            6017..7342
                     /gene="cdeA"
                     /locus_tag="PC503_003279"
     CDS             6017..7342
                     /gene="cdeA"
                     /locus_tag="PC503_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF2529237.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIFALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(7437..8231)
                     /locus_tag="PC503_003280"
     CDS             complement(7437..8231)
                     /locus_tag="PC503_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529238.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8232..9107)
                     /locus_tag="PC503_003281"
     CDS             complement(8232..9107)
                     /locus_tag="PC503_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529239.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9111..9479)
                     /locus_tag="PC503_003282"
     CDS             complement(9111..9479)
                     /locus_tag="PC503_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2529240.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9662..10321)
                     /gene="deoC"
                     /locus_tag="PC503_003283"
     CDS             complement(9662..10321)
                     /gene="deoC"
                     /locus_tag="PC503_003283"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF2529241.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10357..11544)
                     /gene="murJ"
                     /locus_tag="PC503_003284"
     CDS             complement(10357..11544)
                     /gene="murJ"
                     /locus_tag="PC503_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2529242.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(11621..>11950)
                     /locus_tag="PC503_003285"
     CDS             complement(11621..>11950)
                     /locus_tag="PC503_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2529243.1"
                     /translation="DIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWYGR
                     QIVKVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLR
                     LITIQNK"
BASE COUNT         4170 a         1833 c         1343 g         4604 t
ORIGIN      
        1 aattccttaa aagtatgatt aattataatt atataagtat attcttatta cacttatatt
       61 aatttatatt aaatatctac taactcaaat attcataatt aaactttaaa ctggataaat
      121 tttcttttaa gaatgaaagt ttatccagtt ttgcgattat aataaccagt tttacatatc
      181 cacttgtaaa atatatctaa gcaatatatc atactatata gatttatgag tgaaataata
      241 tctgctattt actgaatatt tttatttttc gttttttagg gggattagtt gtgtttaaag
      301 ataagattga tgaatgtgtt catataatga ctgcatatat tgctagttta aaagaatact
      361 attcattcat agaaactcaa attggtgatt ttattaaaaa atatggagaa gatgttgtag
      421 agttatgtct ccatagagtg atgattctac tatgcgaatg tggtttggca taaaattaaa
      481 tttattaaaa tgggtaagaa gaatcctata taatattctt cttacccatt ttaatatatc
      541 aatttcatag cttatcgttt aaaatatttt acatccatta ctagacaact ttacattctc
      601 tttttaattc tagtatattt aaatcatttt agttgctcct tatttattct tattacttgt
      661 tttatttata aaataattct ttttaataat gttttttgtt gatattccta tcacacatcc
      721 aattatttat cattgtcttg aaattgtttg catacttaat ttaatccaat tgaaacaccc
      781 cagcatagaa tcccctgtaa aatagaagtt ggattaaatc ctaacatcta tacagaaaat
      841 actactccaa gcacaagcaa tataatggaa tatatttatc acttaatttt ttatactttt
      901 taaatcccat acctaaaaca ttaagtgcag ctattagaat taataattgt tgtggtataa
      961 aattatgctt gcttcatatt tattcatttt ttgctataaa agttcttgtt ttacaaaaaa
     1021 catttgtttt gtatcaaaat aatacttata aattacataa ttctcataaa aatttctagt
     1081 attacttgta ctcttaataa ataatagcca acaagtacct taaatcatta tatctatatc
     1141 taataagaaa cacagtaaga taatcttttc gcccataact taataaaaac tgttgatatt
     1201 agtagcaatt gaatttagtt aatttattta taatatacat aaatttaaat attacgaata
     1261 aagtattata aataggatac tttctaaggg gaggaaatta tgatagataa tcaaaaatat
     1321 gttattttat cactagaatt acatttattt ttttcaagaa ttatgaaaga gcatgctctt
     1381 tttttagaag caggattcac aaataaaaat tataatcttg ctatggaagc tgaccactat
     1441 aaaaagcaat ttgaagattt attatcatac actgttagtg ctagtaatgg tataattaga
     1501 cctgatatat tatattcaga agagcttgta actactctca catcagttgc agaacaaaaa
     1561 acagaagagt ttacagggat agaaataaac aaaaacatca ctacaagaga attaaatcta
     1621 caaagtggtg taaacccaca agttggtcaa gacttagtga actatgtagc tcaacttaac
     1681 tctgatgcaa taagattact tgatgggctt attaatttta aagaaagagt cttagatggt
     1741 gtactatcat gtactatatt tacatcaaac taccctctac ttcttgaaca tataatacat
     1801 gaagcaaatt tatatcgttc ttatgtagtt gaccttgaaa ataaaataga tattgagtca
     1861 aaaaacgcta aagaaataga attattctgg gaccatatta tgatggaaca tgctctgttt
     1921 atgagaggat tactagaccc ctcagaaggt gaactaataa atacttcaaa tgattttgct
     1981 ataaaattta atgaattaat tgaaaaaaca aacgaaatga ctgattctaa tatcaagaac
     2041 attacagaag aaactctaaa tgaaactgtt gagtttaaag attttaaaga agcaggagca
     2101 tcaggaatag aacagtgtaa gataaaatct ataatattac cacttttagc agaccatgtt
     2161 ttaagagagg caaatcatta tattagaata ttggagagtt ataaaaacat gtaattaaaa
     2221 attactttta aaataatctt tgcatattta gataaaataa aggtacagtt aactgtacct
     2281 ttatttttta taaacttata aaatttaaac aagttattca taaaataaaa taataatcat
     2341 ctataaccca caactttatt ttatattaaa taaaaagtat tagtggttat gttttataag
     2401 tatttcttta ttcagttatt tattaaaaac taatagtaaa tcttatacta atcgcatatt
     2461 tatgttataa ctatattgta actattttcg taatcttagg aaaagattac ttataaaatt
     2521 aaccttatac aataatatat cgtataatct taattagcat aatagttaca atattaaaat
     2581 ttaaatatgg gagtgatttt agtatgataa gacaaacacc attagagaaa cgatatgaca
     2641 agctaggtcc tcatattgta acagcactca aaaaacgtta ttttgatgct tattactgta
     2701 aaactagaaa tgaagctttg caacaaattt tagatttaat tcctcaaaat catgtagtat
     2761 catggggagg atctgaaaca cttaaagaaa tgggcgtaca aactgctgtt agagagaaag
     2821 gatttaaagt tattgataga gatttagcaa aaactccaga agaaagaact gaaattatgc
     2881 gtcaagcact tctatgcgat acttttttga tgagtagcaa tgcaattagt gaagatggac
     2941 aactctttaa tattgatgga aatggcaatc gtgtagctgc aatgatattt ggtccaaaaa
     3001 atgttatagt tgtagctggt atgaataaaa ttgtaaaaaa cattgatgat gcaatacaaa
     3061 gaactagaac aattgcatct ccagcagttg ttcagcgttt tcaagatgtc aatacaccat
     3121 gctatattaa tggaagttgt atagattgca caagtcctga aagcatttgt gcatacatgg
     3181 ttactacaag aatcagtcgt ccagcaaaaa aaataaaggt aatattggta ggagaaaatc
     3241 ttggtctata aaatatacat acatgtaaat agctctataa ataataaaat catatgaaat
     3301 aacttatttc taaaagtggt agaataaaag cttctacaag actttcattc tgccactttt
     3361 atattctttt aatttgtgtt tctatattat taattgctcc aattttcata tatattacta
     3421 actattttta ttttcataat ttttttgttc ttcatcaagc tgtttataat aatctttatt
     3481 atagtcagct agataatcta taccacctcc tgtaatcaca tttaataatt tcattgcaga
     3541 ttcttgatta actttacaaa cataattatc accagattta acaagctcta atgtaatatt
     3601 aaattctttt ttctttgcag aatcaatatc tttcatagtt ggatttggca tcatttctcc
     3661 tagtttagga ggattctttt ttaaaataga aaccatatca gtattgttaa tttttaaatc
     3721 tacagtcact ttatccttat tattttttat atctgaaatt tcccaagtca tatttttaga
     3781 atacatttta aatccttctt tatcttcgta tataagatta cctaaccctg attttgggaa
     3841 atacttatca acagtatctg catcttgtgt ttttattgaa ttaaacatac tatccacttc
     3901 attttttatc ttattatcat tagtacaacc agctaacacc agtactgata ttgcaaacat
     3961 tataatacat agaataaatt tcttcattaa attatatccc cctatacttt tttgcacaaa
     4021 tattattctc ttttttatct tttgaaaaag ttgtagtaat tgcattttgt ggacaaactt
     4081 ttatacattc accacaccta atacagtctg gactatttac atctttatat attggtatat
     4141 caagcttaca ttttgtttga catgctgtac aatttgtaca tttatcttta tcaattttaa
     4201 atctatatat tgaaatagga ttaaaaaaac catagattgc tcctaaaggg catatatact
     4261 tgcaaaatgg cctataagta atgattgaca tcaataatat caataacaaa atacttaact
     4321 tccagctaaa taaaaatcct attgattctc ttaaattctc atttcctaaa ataagtggta
     4381 ttcctcccaa aagtgttcct gaagggcaaa tccatttaca aaaccaagga tttccacccc
     4441 ctgctacatt tacaatagca actggcaaaa taattacaaa tattattaag actatatact
     4501 ttagatattt tagatattta tcaccataaa ctttttttat ctttactgga aagggtactt
     4561 tatgtagtaa atcttgtaca agtccaaagg gacaaagcca accacaaaca aatctgccaa
     4621 aaaaagcacc aaatgccatt aaaaaaccaa caacataaaa tgagaattta tactctctgc
     4681 ttgataaaac tgcttgtaat gaacctattg gacatgctcc aagtgcacct ggacatgaat
     4741 aacaattcaa tccaggtaca cataattttt tactttctcc tccatatata gttccttcta
     4801 aaaatccatt tacatatcca tttgttaatg ctgtaaatgc aacttgagta ataagtctta
     4861 tattattatt tactttagat aataacttca ttcctcttct cctaaccaat accaatacac
     4921 tcaagacaaa tcataattgc tttagttaat actgtatttg tttctccacg atatgtacct
     4981 aatgcaataa atataatact aattgcaata atagaaatgc cttttttatt atctttaata
     5041 aagttactca ttggctttta ccatttttag tctttcatct ataatttttt tccaatcttc
     5101 cttactattt gcacctacaa ccttctcacc cacaaagttt cctttcttgt ctacaaaata
     5161 agttgttgga aactccataa ctcttttaaa atcagttttt ttaagttctt cagatacagt
     5221 caattgttgg taagttgcat ctgacttttt cataatgtct ttaactaaat ttttctcttc
     5281 atttgaaaga ccagttctca tatcagtttt atcaacttct acaactaatc cctttatagc
     5341 tacattggaa ttattactct catattcttt tgataatgct tcaagctctg gcatttcacc
     5401 cacacatggt ccacaccaag tagtccagac attaataaga gtaagttctt tatttgaaaa
     5461 tatctctttt gttaccttat ttccatcaac atcctccgta tctaaattac taaaccattc
     5521 actattattc ttgttttttt ctactggctt agattctttt ttgctacatc cagaaatcat
     5581 acctaaaaca caaatacatc ctaaaactac tatgaaaaac cttttcatat ctcacactcc
     5641 tagaatttat atagtatata aaatcgctgc ttgaaataaa aataacttat cttctatatt
     5701 aaagtaatta tatttaataa ataagagcta atttaaaaaa agatatacag ttaaaatcta
     5761 tttcttttca gacaaaatct tatatatata taatagcttg taaatcttaa gattatatac
     5821 atatatttct aaagattttc ttaagaaaca gttagatttt actaatataa gtttattaat
     5881 tagcattata ctaatttatc ttaatatgat tttttgttga ttttaagctg tttatcgtat
     5941 aaataaaatt tttcttgact atatagttac tatatagctt attatatata gagagtaata
     6001 aaaggaggta aaatttatgg aaaatttatt tacaagaaaa ttcactactt ttgaatttct
     6061 aaaatttgtt tctcctgcaa ttatatccat gatatttata tctttgtaca caataataga
     6121 tggcatcttt gtatcgacat tagttggttc tgatgctctt gctagtataa atattgtact
     6181 acctataatt aaccttgttt gtggatttgg aataatgatg gcaactggtg gaggtgctat
     6241 cgtttctata cgtatgggtg aaaatagaca ggatgaagcc aactctacat tttcttttat
     6301 agttttgttt tcattgattg ttgggatttt attcacagta atctcatatt tctttatcaa
     6361 agaaatatct attttgcttg gtgcaacaga taagttatta ccatattgta taacttatgg
     6421 taaagttatg attttatgta caccatttta tattttaaaa tttatatttg agtactttgc
     6481 aagaactgat ggaaattcta aatttagttt atttctatca gtcattggtg gtgtaacaaa
     6541 tataatattg gattatgtat ttattaaata ttttggaatg ggtcttttag gagctgcagt
     6601 tgcaactgct ataggtatta ttttaacttg tgttttaggt attatttact tcttatctaa
     6661 taaatctaca ctaaaattaa gaaaaccaaa aaccgatttt agacttataa gagatactat
     6721 gataaatggt tcttctgaaa tggttacaga attatctaca ggaattacaa cattcttatt
     6781 taatgtagta gctttaaaat tagcaggaga aaatggactt gctgctctta ctatagtatt
     6841 gtatgctcat tttttaatga catcagtcta tctaggattc gctgctggag tgtctccatt
     6901 aataagctat aattttggtg ctgaaaacag tgataaatta aaagaaacat ttaaacattc
     6961 tctaaaattt atatttgttt cttctctttt agtgtttatt tttgctttag tatttgcacc
     7021 atttattgtt agggtctttg taagtccaga taacacagta tttaaactag ccttacaagg
     7081 attaaaaata tttgcatttg cttttttgtt tgttggtata aatatatttg catcaggatt
     7141 ttttacagca tttcacaatg gaaaaatttc agctattata tcttttagtc gtgcctttgt
     7201 ttttataatc ataggaatca taattcttcc tcctatgtta aacatgactg gattatggct
     7261 tacagttcca tttgctgagg ttataaccat atttatatct attctattta taaaaaaata
     7321 taaatgtaga tataagtatt aaaaattaat acttaaaatc aacatttatt aaaactaata
     7381 aacctgcttt aaaatacaaa tttacaaatt tgatttttaa gcaggtttta ttttagttat
     7441 aataagtcat ttgcatactc tttaattggt gcttttctaa gtaataaaat tataaatatt
     7501 atgcaaataa ctataattcc tacttttgtt ccaaataaaa taaaaggatt ctgaaatgaa
     7561 taaataattt tttctaaata caatagcatt ttatgcatat ttttagttgc aaaattaact
     7621 atataaatta tcattaatat cggtaatcct atcaatatag taatactagt aacttttcta
     7681 actctatatg taaaagctcc aagtaacact cctataaaac ctatacatat ttcatttata
     7741 catatttgta caaaataatt taaataagtt agtggcatac ttgatgttga aggatctatc
     7801 agtgctgata tagatgtcca aatcatatct ctctttagta aaactgatag ttctatactg
     7861 taacctgtta taatttctat aaataacttc gataaaaaaa tcaaaactat acctaaaata
     7921 gaaatcacaa agcttaaaat aattaaatct atgacaatag cttttataca actttttcta
     7981 tctgctctta tacttaaagc tcctgaaaag tctttatttg ctatatttac tccatacaca
     8041 aatagcagta tagttatata tgttaaaata ggattcacaa tcgtggataa attagtttta
     8101 gatgcttctc caaaaatctt gagaataaac actggcaaaa tattcataac aattcccaca
     8161 atcataaata taattatata caatttagta tttttattaa aaaattttat atatggcttt
     8221 aattcattca attacaattc ctccttctta gtcatgttaa caaacatatc ttgtagccct
     8281 atgtatccta catcaatatt tgaattttta agtatttttt catcactttc actaaaatca
     8341 ccatagtaaa aataagcaac tgcatttcca aatgcctttt taggttttat attttttata
     8401 cattctaatt tttctaactc ttctttattt ccagtaatat aatgagcttt ttgttttatg
     8461 acatcaattt cttcatctat aataattttt ccctcattta atattattac atgctccagt
     8521 aaatcatcta tttcatcaat caaatgagtt gatattatta ttgtccttgg attttttata
     8581 taactatcta aaattatgtt ataaaactct tgtctattta ctgcatccag accaattgtt
     8641 ggctcatcaa atatggtgat agctgaatta gaacaaatac ctattatatt tgaaagtata
     8701 gttttcatac ctcttgacag ttgtttatac ttttttttag tatttaaatc aaaatatttg
     8761 cataattctt cttctaagcc tttatcataa cttttataaa aactagaaga aaattcaaat
     8821 atctgaccta ctttaaaatc tggactataa aattcttttt ccctaacgat acaaacttct
     8881 tccaaaactt ttatatcttc ttttgggttc tttcctaata tttctatctc accttcattt
     8941 tgaattaact gatttaccat tatatttaat aatgttgttt ttccagctcc attcttacct
     9001 aataaaccat atatcttatt tttttcaaag cttagagaca tattattaaa aatattttgc
     9061 ttcttaaaac tgtgagataa attttctatc ttaatagaac tactcatata ttaatcctcc
     9121 ttgaaattaa ttataatatc aaccaattct tctctattta tttctaattt gttagcttct
     9181 tgaagtaggt tttttacaaa attatgttta aaattttctt ttctagcttc ttttataata
     9241 gtttttgcac catctgatac aaacatccct atccccctct tcttatataa aatattttta
     9301 tcaaccaata tatttatacc ttttaatact gtagctggat taattttata aagctttgaa
     9361 agctctgttg ttgatggaac ctgttcttct tcttttattc catttgatag tatctcatct
     9421 tcaattgctc gtgctatctg aataaatata ggttcttcat tatttaatac taatttcata
     9481 ggttcctcct ttctccatca gttagttact caactaatta actatataac ttataatatc
     9541 ttgaaaaata ttttctgtca atactaaata aaaaacagag ggaaaattcc ctctgttttt
     9601 tgttctttat atttataatt aaattttgat ttttgtaatc ctatcccata agttaaaaac
     9661 tttaataatc tgttgtatct tcatttttta atattttaca tattgagcta gttcctaacc
     9721 tttctgctcc tgcctctata aatttttctg catcagaaat tgatttaact ccccctgcag
     9781 cttttatttt tacatttttt ccaacatgct ctttcataag ttttatatct tctaaagtag
     9841 ctccacctgt tcccattcca gtagatgttt ttataaaatc tgaacctgac attgttacta
     9901 tttcacacat ttttattttt tcatcttcat ctaaataaca tgtctctata atgactttta
     9961 atactttatc tcctatagct ttttttattt cttttatttc ttttcctata ttatcataat
    10021 ctttattttt tatatctgaa atgtttacaa ccatatcaac ttcatctgct ccattttcaa
    10081 tagcatcttt tgcttcaaat acttttgtag cagtagtttg atatcccaaa gggaacccta
    10141 tcactgtaca tatctttatt ttacctttta gatattctga tgctcttttc acatatgatg
    10201 gtggtatgca aactgatgct acactcatat ctacagcttc atcacataaa attttaatat
    10261 cttcccatgt agttgtagct tttaaaatag tatggtctac tgtttttaat atatgtttca
    10321 taaaatcctc ctaaatttat aattaatata attagattac ttttttaaat gcaattttct
    10381 ctttgcaatg tttagtatca tatcaacctc ttcaacttta aaaataatca ttagtagtgt
    10441 ataaattcca cctccaacta taactgaaat agctagtgat acaaactcat taaatgttcc
    10501 tactcccaaa attccaaata taaatttata cgtaaagtat gataaaacac ccataattaa
    10561 agatgcaact accgatttca aagttgcttt tattatttta tcttgtccaa aatatccaac
    10621 ttttctcttt aggttcaaga agagtaacaa tatacatgca attgatgatg aactagttgc
    10681 aagagcaaga ccaccatgag ccattggttt tattaaaact aagtccaata ctatatttac
    10741 ccctacagat ataatcccat ttaccatagg tgtttttgtg tcttgtaatg aataaaaaac
    10801 ctttcccaaa atatctctta agccaaatgc agtcatacca actgcataaa aaattaaggc
    10861 agttgctgtc atttgggttg ccctcgcatc aaaagcacct ctctcaaaaa tgattctaac
    10921 aacaggagtt gcaaaaaaaa tagaagcaac tgaaatagga atcatagaaa ttattatcat
    10981 atttatactg gatttaactg aactagtaaa cttcttttga ttattttctg cacttaactt
    11041 agataacata ggatacataa cagatactat tgaagctgta aatgtccctg taacaaaacc
    11101 atttaatcta tctgcataag taagtgctgg aatgcttcct ttaactaatg ttgaggctaa
    11161 agttgtatct accaatgagt tcacttgatt aacagcaaca cctataaata ctggtgaaag
    11221 taatgctagt aatttaataa ggctatcatc tttaaagttt aagtagtata agtatttgta
    11281 gttcgttttt ttaacaaaaa acatgtaaaa gagcagttga actaccatag caaccacagc
    11341 accaattgga agtatgtatg gtccaaatat ggtacttaac attattgaaa taattattac
    11401 tatattatag ggtatacttc caaatccaac tacaataaag ttctctttaa tttgtaaaaa
    11461 tgctgacata acactcgtaa tacctatgaa tattattcct gttctgaacc tcccatgact
    11521 aaagtcacag ggttcctgct tcatagaatt ttgcatacta aaatatgtct tactaattct
    11581 ccacaggcta tccccgtagt tcctacggtt cttacatacg ttatttattt tgaattgtta
    11641 ttagtcttaa tccttctttt aatatattta tacttgcatt tatatctcta tcgtgagttt
    11701 cattacaact aggacaaatc cattctctta tatttaagtt cttaacttcc tcgtttttat
    11761 acccacattt attgcatatt tgtgaacttg caaagaattt acctaccttt acaatttgtc
    11821 taccatacca attagccttg tattctaatt gacgaataaa ctctgaccat gatacatcag
    11881 aaattaagcg agatagttta cgatttctaa tcatattctt tacttgtaaa tcttctatgc
    11941 aaataatatc
//
LOCUS       DAMJWC010000097        11752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMJWC010000097 DAMJWC010000000
VERSION     DAMJWC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.101"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            326..1504
                     /locus_tag="PC503_003286"
     CDS             326..1504
                     /locus_tag="PC503_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2529244.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            1854..2735
                     /locus_tag="PC503_003287"
     CDS             1854..2735
                     /locus_tag="PC503_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2529245.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            2720..3093
                     /locus_tag="PC503_003288"
                     /pseudo
     CDS             2720..3093
                     /locus_tag="PC503_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(3353..5920)
                     /locus_tag="PC503_003289"
     CDS             complement(3353..5920)
                     /locus_tag="PC503_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2529246.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYMSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5923..6528)
                     /locus_tag="PC503_003290"
     CDS             complement(5923..6528)
                     /locus_tag="PC503_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529247.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLNGIMNDGGE"
     gene            complement(6902..8362)
                     /locus_tag="PC503_003291"
     CDS             complement(6902..8362)
                     /locus_tag="PC503_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2529248.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRGNIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8716..9294
                     /locus_tag="PC503_003292"
     CDS             8716..9294
                     /locus_tag="PC503_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529249.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            9585..10835
                     /locus_tag="PC503_003293"
     CDS             9585..10835
                     /locus_tag="PC503_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2529250.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10996..11565
                     /locus_tag="PC503_003294"
     CDS             10996..11565
                     /locus_tag="PC503_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2529251.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         4070 a         1937 c         1639 g         4106 t
ORIGIN      
        1 tacacataat tatcatacat gctatatgta attactatac ttatacacat aactatcata
       61 catgctatat gtaattacta tacttataca cataactatt atactttcca tacataatta
      121 ctatatttgg acacatagtt atcatacata ctgtatatta agatataata ctttttaaat
      181 tttatataac acagacacat gcaataaaaa agaaggtatc cataataagc tctttgcatg
      241 tacctaaata aaaactgtaa aatagaatat ataaaatcta atctatttta agtaaataca
      301 atttcacttt aaaagaggat gtactatgaa ataccatata tttttaatca taactactat
      361 attaataatc gaactatgta acatttacat atgcaaaata gcatcttttg gaaacaaaaa
      421 tataactata cataagaatt acaaatatat ttttttaata aaaccattaa ccttcttgat
      481 aataatattc acaaaattac cattaccact atattatata ttgttttaca tagtaagtca
      541 taaattgctc ttaagcagaa aaagttctac taacaaccat tttattccca atatggcagt
      601 aataagtttt tgtattttac accttattac tgtaagtaca atatcacttg ttaaaaatac
      661 aagtccagat ataatatttg caaatatgac ctataagtta attagtattt taatagcttc
      721 tattttagat tttatcttat ggtactctat gaataaaata aaagagcata tttatataat
      781 aactcaaaat caaatagagt tcagtctatt tttaaaattt atctggttca ctttaggata
      841 tatattattt gatagtatac aaattacatt tgctccacca agttctctaa cttcctactt
      901 tatattggga agtaacatat tattaatctt acaactaatt atattcatca atcatatata
      961 ttccattgaa aaaaatattt atttagaaaa agaacataat agactaaaaa tgataaaaca
     1021 agaacaatta ctaaaagtaa atttattaaa gaaaaaagct aacattgatg aattaacatc
     1081 agcatataat cgaaaatttg cttttgaaaa aatacagcat tacattgata acaatttatt
     1141 attttcattg atatatatcg atttggataa attaaagacg ataaatgata catatggaca
     1201 tttagctggg gataactata ttattaactt ctcaagtata gttattgaaa acttaggaat
     1261 agatgacata tttgctagaa taggaggaga tgagtttata gttattatgc ctaaatctaa
     1321 tgaaaacacc acaaaagaat ttatagagaa aataagtaaa attatggata atacgatatc
     1381 ttttagctat ggtattgtag aagtttctag cgaaaacaaa atgactgtag aagaaattat
     1441 taatattgct gatattagaa tgtacactaa taaacaaaat aatcataaaa ggaacaataa
     1501 ctaaaatgaa tatttacatg agcttacttg tagtctcact atgtttttta tcttattatc
     1561 tctatcatta taattttttt aaatatctgg acataatgat taataactct aaaaataaat
     1621 acacagtata tattatatat tctatattta attatttaat ttttattatt tgtacttatt
     1681 taaagtttca tctaattata aattggacaa tttttatgtt gattttattc atacaaatta
     1741 aagtaactta taaaatctcc acaataaaaa acatttttta ttcactaaac tgctccatca
     1801 ttggtttagc aataaatata ttttttaggt ctttaatgtc aatagtgtta aatatgccag
     1861 catatttatt tgatagtaat tctattgcaa atatttacag agtatttcct atatcattta
     1921 gctttatagt tacaggacta tatttcagtt ataaaaataa taaaaataat aagattaact
     1981 ttgaggcagt tttagaggac aaaaaaaact taattttctt attgagcctt atgtttggaa
     2041 tgtacttgta tctatgtttg agtttgtcaa tatactatac tgttggaaat gtattgattt
     2101 taaaattata tggaatcaag tctgccataa tagttttggt aggtaactat attgcagaaa
     2161 gatatagctt tagaattact caaataaaag gttatgatat taaaaatcaa atagaatatg
     2221 tagaaagtgt aaagacagaa tatgagatta ataaattgaa tgatattgta tatacagatt
     2281 tactgacagg tttctacaat agaccttttg tgaatcaaaa actatcagaa tggacatcaa
     2341 atcactacaa atttacctta tgttttactg atttaaatag cttaaaacct gtaaatgata
     2401 aatttggaca ccaatttggt gataaataca tatccactac tgctcaaata ataaaaaaac
     2461 ttataaatgt agaaaattcc ttactattta gatatggtgg agatgaattt ttattccttt
     2521 tacagaatac aagttgtgta gaagcagaaa agataatgat taatataaat tatgaattat
     2581 caaaattaag taatactgac gagtatcctt atgctctttc cataagctat ggattagttg
     2641 agtgggatgg aatatccgat attgaaactt taatatcaaa ggcagattct ttgatgtatg
     2701 aaaataagct taaaaataaa tctactttaa actagctagt taagatattc tacaaaatat
     2761 atgttataag agagtactaa gaatatcaaa atatatagat tttgcaaata ttgaatacag
     2821 tttactaatg aatgcactgg atgtaagtgt tagtaaacac ctattagatg aacactttac
     2881 tgttgtttgg gctaatgacc gttattatga aatgttcagc tatacctagc taaaaagtta
     2941 aaaatgacca ctgtagccga gggaatagag accagttttc aaaaagattt cttgcaagaa
     3001 ataaactgtg atatgttaca aggatacgtg ttctctagac ctttaccaat aaaagacttt
     3061 gaaaaactta tgtttcaaaa ctcctccaat taacaatata aaattgctta ttataagtga
     3121 tattattgta tcaacaaata aaggaattgt ctcaaaattg attttttcta atcaaatttt
     3181 tattttgaga cattctcatt tttttgcata agaaaatacc caccaagcta cggtttttct
     3241 taccgctgtt cggtgggtat tagtagtatt atgaaatctg aaaactttaa gtattactac
     3301 ttccgctaac gcaatcacaa aggtcgaaag cttcaaagcg aaaataggct ttttactcat
     3361 caaacgtcac cgtacctgcc aacccgtcca ccgttatcat ttgtccgctc ttaatagttc
     3421 gtgtggcaat gtgtgtagcc ataacggctg ggatgccata ttcacgtgcg acaatgcttg
     3481 aatggctaag aggaccacca atgtccgtta caatcgcact tgcagatgaa aataatggtg
     3541 tccatgctgg agttgtggta actgcaacca aaacacttcc aggttgaaag ctttcaaaat
     3601 ctgctggact attcagtaca caagctggag ccgtcacaac accagtactg gtaccaatgc
     3661 ccgtcaacac aattttccca tctttctgct tctgttgtgc ttgtgatata gtttttttgt
     3721 ttttctctgg caacttggat ggtgacatat aacccatgta ttttttaagt tcagcttttc
     3781 gaacaggtat tatcccgttc atatcagata gagacttgtt tttatccaac tgctctataa
     3841 gtacctccaa ttccgatttt gtgagccaat aaatatcatc taaatgtgaa atagctcctc
     3901 ctcgtatgaa tcgttctgag atttcctgaa acatacaacg aatcagagga tgtcccattc
     3961 ccatcaaata aatagcattt tcacgcatag gagaggtttc ctgtgcccaa tggagcaact
     4021 taaaaaatag ttttttacgc aatccaccta tgtgttgtaa aatctcttct tctgcatgtt
     4081 ttctacgctt ttcaaacgtg gtctggcgta aaaaaggact ttcccctttt ccttccacaa
     4141 atgtttttac ggattcaaaa gttggtgtaa gtgtttcctg cggtgtggaa tgcgcaaaat
     4201 caaactcata agcggtacga ccaaactctt taaagtactt attgattcga tttttccatt
     4261 ctatccatac ttcctgtgaa actccaacag gcacaactga agacatgaaa tcttctgcta
     4321 tctttattgc aggactgttt tgcagataaa ggttgatgct gttattttgc tttacccatt
     4381 ctgaaatacc ccacaactcc ttttccgatt gcagaacaat cgtatcaaac ccaagcagga
     4441 aaacggaagt atccgttata ccagcacgtc gaactgctcc ttgaaataat tttgtaaata
     4501 atgtttcact gatagaagca gcaggcaatg taagctgaat ccttgtgaaa taaatacatg
     4561 cggcataaaa tattgtctga ataccctcca taatttgatg ggcgttcata gtatgcaggg
     4621 gcttttcttc ccattgttta atagcatcct catatccttt tcgtgccgtt tcccagcgtg
     4681 caacgctgtt cataagtgtc ctacgtaaag agcgtgggga aagggatttg atagcaatca
     4741 aaagtggctt tgatttagca gaaagataaa catatccatt aataaccgta tatgccccgt
     4801 tttttggtaa taattttttc gcacttttac caaacatatc tatccataaa agctctgatg
     4861 cacggtttac gatttcaaga ccaagtgtgg cgaacaaagg tgtaacagga tttggcaaat
     4921 gttctgccaa acttcccttt gtgtatacaa catcctgttc tggcaatacc cattctggtg
     4981 gcagaacagt aattggacga gcctgaacaa tgtacaattt atctttttcc agtgcccact
     5041 ctacatccat aggcatttga taatacttct caattttctt tccaagctgt atcagttgca
     5101 ttacctgatt acgagtaaga gcatattttt ttctcaacct ttcaggaacc atggtttctt
     5161 ctgttccttc tgaagtacga accgtcataa tctctttatt tgccacttca tacgatataa
     5221 ttcgttcgga gtccttatcc actacgattg tatcgggtgt aactaagcta gaaaccaccg
     5281 cttcaccaag cccccatgca gcgttaataa tcatttcgct acgtctacca ttgattgggt
     5341 ttaacgtaaa cataatacca gatgaatcgg aaaatgcaag cttttgtact acaacagcaa
     5401 gtgcgacaat ctcgtgcttt atattattct tcacacgata agcaatagca cgagctgtcc
     5461 ataaggaagc ccagcatctc tttacagagt caataacttt atcttcacct tgtatgttaa
     5521 gataagtttc ctgctgacct gcaaaagaag cgtcaggtaa atcttcagca gtcgcagacg
     5581 aacggacagc caccgatatg ttccctaatc cagcataagc cattttaatt gcgtccgaca
     5641 cttcctgtgg catttctcca ttatggaaaa gctcccctat tttcttagat acatcttcaa
     5701 gttggctggt attattggaa tcaataccat ctagcagttt attaattcga gactgaatat
     5761 ggttcgtctc aacaaaaatc tggtatgaag cagtcgtaac atgaaaaccg tctggcacag
     5821 ggatgcctgc tgtcaatagt tttgataaag acatcccttt tccaccaaca atttcaatgg
     5881 ttgcttgttt atgttccagt ggcaagacat aataaatcat aatcattcac ctccatcatt
     5941 cataattccg ttcagaaata tattcattgt ttcatccaac attttttccg aactatccaa
     6001 tggtcgtgac gtgtagctga ttgataacat ggagttaatt aacaaacgtg tcacaagagc
     6061 ggtatccgtt ttgcgaaaga tgcctgtggt cacaccatta tcaattaccg attttataat
     6121 atcttgatat gcataacgag catctttaag tctctttcga tactcttctt ctaaataatc
     6181 agattctgta tttaaccaca tcagtacagt tctatactgc tctggaaatc taagatgatt
     6241 aagcatgatt tttctaaggc actgttgtgg tgaaggttca ccatcaataa tcctatgaac
     6301 ttgttggata gttttttcta tttctttctc aactgcatat acaacaatct cgtctttcgt
     6361 tttaaaaaaa tcgtatagac ttgactttcc catgttggct aaaactgcaa tttctctcat
     6421 tgatgttttt tggaatccat tttcagccat gagactcaaa gcaacagcaa ctattttttc
     6481 tcggcgttct gcttgttgtt cgggtgtaag cacaattcct tttggcatag tgcgatacct
     6541 ccttttagcg accactggtc gtttcttttt tatttatcat acagcaacca acggtcactt
     6601 gtcaaggtta atttttttca ttgtatatgg tactcgagat aaaaatgttc attttagaaa
     6661 ttactctatt taagtagaaa taggcttcat cattagaaag caagactata aatttgagat
     6721 atttatcatg ttcaaatttc atcaatatca aagtttaaaa tattaataaa aaaagaatta
     6781 ctaagaaata acatataaag attcaaaaaa ggagttgaac ttaaaattca attacaaaaa
     6841 atcaaattta agacaactcc tttattcttt atctctacta ttctttatct ctatttattt
     6901 attacaactc cctaacattt accactactg ccttaggtct agtcatagcc tcaattgaat
     6961 acttaacacc ttgagttccc ataccagatg cctttacacc taaaaatggg aagtggtctg
     7021 gacctctttc agtcttatta tttatttgaa cagtaccaac ttcaagttta tcagctatat
     7081 aaaatgcctt atcaatatca cttgtaaata ctgatgattg aagcccatac tctgattgat
     7141 tagcaatttc aattgcttga tttatatctt taactcttat aattggaagt actggaccaa
     7201 atggttcttc ccaagcaatt ttcatatcaa catttacatt atctaacaat gttggataga
     7261 ataaattatt ttttctaaca ttgcctgtta ttaactttgc tcctttatgt aatgcatcat
     7321 caaccaaccc ttgaacaaaa tcagttgctt tattatctat aagaggagtg ataactactt
     7381 catccattgg atttccaatt gtcaacttct ctaccaatgg ctttattttt ccgactaatt
     7441 tatccgccac actctcttgt actaaaattc tctttactgc cgtacatctt tgtcctgaat
     7501 atgaatacgc tccagatact atattcttag ctgcaaaatc taagtctgca tcttctaata
     7561 ctatagccgc atcttttcca ccaagctcca ataataatgg taccattcca gatattttag
     7621 atatatgctg accaacttca gtactaccag taaagttaat aaaattaatt cctttatgcg
     7681 ttacaacata atcccctatc tcactacccc tacctgtaat agtattaagt actccatctg
     7741 gtatcccagc ttttctcata atttctacca catgaagtgc gctaatagcc ccttgtgtag
     7801 caggttttaa tacgactgca tttccaccaa taagtgctgg agcaatcttt gacattgata
     7861 aatttacagg ataattaaaa ggagatatag ctaaaacagt acctaatgga acccttgaaa
     7921 cataagacat cttatttctt gttccaccag ggaaattatc tccactaatg gcttctccct
     7981 ccatattttt tcccacatca gctgtgtatc ttaaaaaatc tgctgttctc tcaacttctg
     8041 cccttgcaga ttttatgtct ttggctattt caagtaccag tatattagct atctcatcta
     8101 tattttctaa caataaatca gcagccttat gaaatatatt gcctctcttg tatacaggca
     8161 tttcagccca tacttttata ctctcttttg tgttttttat aacctcatct acctcatgtt
     8221 ttgtcataga ttgtactttc ccaacaagag aattatctat tggtgagtaa atttctattg
     8281 gctttctcga attagattct acccattttc catttattaa atttttatat acattttctt
     8341 ttgttttaag ttcattaaac atatttttat tcctctctct gatataactt tgtgtattta
     8401 aattatagcc atttattcgt tatgtaaaca tttctttttt tcataaacgt ttacctataa
     8461 aaaaatttta agttaacgtt tttctacatt cttctatttt aataacatac tcgctccaaa
     8521 tctatatagg tcacacttta atactaatat atcaatatac caatatacca atataccaat
     8581 ataccaatat accaatataa atattataaa cataaatcac ttgacaaatt tataagtaga
     8641 caatattata tatctatgac tcaaaatatt tttaaagtca tatatatcat atatagacag
     8701 aaaggattga taaaaatggc taaaagtttt acagaaatag aaaaagacaa tataagaaaa
     8761 agactaattt cagaatgtga aatcaactgg tctaaatatg gatacaaaaa aactaatatt
     8821 gatgaacttt gttcaaaatc aggaattgca aagggttctt tctatacatt ttttgattca
     8881 aaagaaaagt tattttttga agtattaaat ggaatccaaa acagacttat atcatcagta
     8941 gatgaaattt taagtaacat gcctccaaaa gaaggctttg caaaatcctt aaaaatgtta
     9001 tatcgattat atgataaaaa tccattttta tattcaccaa ataatcctga tttcatcagc
     9061 ctaataaata aactacctca agatatgttt ttacaacttg agtccaataa catacaaagt
     9121 ttttacgact taattgagag acacaatctc aagttgaaga tagaaaaaga aaaagttttt
     9181 ggtgtttgta atgctctact atcaagtctg ttggtaaaag aaaatattga atataactat
     9241 attgaagtgt ttgactttat ggtggataat cttgtagaac acatacttga ataacaattt
     9301 aaaataattt ttctaagtat ttttttatac taaataggat taatatgatt gaattaatgc
     9361 aaaaaataaa caatataatt tataaaataa atgataaact aaatatcaca caaaacttat
     9421 agaccctaga gcaaacccat tccactctac tctaagccat ctataatagt ttgtatattt
     9481 ctaataatat tagatattaa agtaagaaaa aaattcctta taataattgc tattatatca
     9541 attattgtaa atgttttaat aatcttagat aggtaggtac atatatggta aaatcctcga
     9601 acacttttaa taaaaacttc aacttgatga tattaggtca aataatctca ttgtttggtg
     9661 catcaatact taaatttgct ttatctttat acatacttga tataactggt aaagcagaaa
     9721 tatttgctac tatactagca gtatcttcaa tcccaattat agtattctcc cctattggtg
     9781 gagctattgc agatatattc aacagaagaa acttaatggt tatttttgat ttttcaagta
     9841 gtcttacagt actaatctta gcagtattct tattcaacaa taatggttca atattacttg
     9901 taggaattat tatgaccata ttatcagtca taagcacaat gtatcaacca actgttcagt
     9961 caagtacacc ccttttagtt gataatgagc atttaatgaa tgcaaatggt attgtagctg
    10021 gagttgcatc tcttacaaat attgcaggac ctgtattagg aggtgtcttg tatggtgtga
    10081 ttggaattaa tgcaattata gttataagtt gtgtaagttt ctttctatct gcaattatgg
    10141 agatatttat acagattcct tttatcaaac aagagcaaaa cagcaacatt ataaaaacta
    10201 tatttactga tataaaggat ggtattgttc atatatgtaa agaaaataga tttatactaa
    10261 aaatactttt tttagctata gcaataaact tatttttaag ctctatgtta atagttggta
    10321 tcccctatat agtaaaaatc actatgggag ctagtaactt cttatatggt ctagcagaag
    10381 gagcaatttc ttttagttca ctggtagctg ctgttagtat tggtattttc tcaaaacatc
    10441 taaaaatcac taatttgcat atttccttta ttatatgtgc agttatgttc ataccaatgg
    10501 cggtttcagt atatccattt atattaaaca caggatttcc agttccattt ttaatcttta
    10561 tagtatcatc tatgctaata ttttttacaa cgactcttat ctcaatatat gttataacag
    10621 tcacacaatt aaaaactcca aatgaactct taggaaaagt aatgtcaatt ctttttgcag
    10681 gaacagcaat tgcaatgccc cttggtcagg ttatgtatgg taaacttttt gatttattat
    10741 cagatagagt gtacatcatt atactaggag ttggatttat tacattactt atagcatttg
    10801 tatcaaagat aacattgagg aacgaaaatc tttagataca aagaatttag atataaagat
    10861 ttaattttca ctaatttctg aatttaaatg caaaattgtg tatcagtatg ttgacgtttt
    10921 agaaattgat tgatataatc aatggaaaat aaactttata aaaattcaaa atattcagct
    10981 agaggagtga taaaaatgag ttacatgcca actttagaac aagcatggga aatattaaga
    11041 aaatacaata aggaagaatt tcatataaga catgctcaaa ttgtatctgg agttatgaga
    11101 tactatgcaa aggagtacga ccctgaaaga gtagaatttt gggaaatagt tggactttta
    11161 catgatttag attttgaaat gtatcctgat gaacattgtg ttaaacaaag agaattaatg
    11221 acagagcttg atttagataa atcaataatc gattctacaa taagtcatgg atatggatta
    11281 actggttcag atgttaaacc agagcaattt atggagaaag tattatttgc tgtggatgaa
    11341 cttactggtt taattggtgc tgctgcaata atgcgtcctt caaagagcgt ttctgattta
    11401 gaattaaaat ctgttaagaa gaaatttaaa gataaatcat ttgctgctgg ctgttctcga
    11461 gacgttataa gaagtggtgc agaaatgctt ggatgggaac ttgataagct tatccaaaca
    11521 actatagaag ctatgagaag cttgattcca gagatggcaa tatagctcct ccatacatat
    11581 accatagaag ttacatcttt aaagagcatt tctctttttg atgcaacttc tttttatatt
    11641 ttgtagaata aaaagtttaa tattttaaac tcactatata ataaataata taatgtataa
    11701 tagtcataaa ctttctaacc ttaaaagttt ctaataatca ataaacaatt ct
//
LOCUS       DAMJWC010000098        11631 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMJWC010000098 DAMJWC010000000
VERSION     DAMJWC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11631
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.102"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            16..2193
                     /locus_tag="PC503_003295"
     CDS             16..2193
                     /locus_tag="PC503_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2529252.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYKQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEANCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2207..2629
                     /locus_tag="PC503_003296"
     CDS             2207..2629
                     /locus_tag="PC503_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2529253.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            2803..3378
                     /locus_tag="PC503_003297"
     CDS             2803..3378
                     /locus_tag="PC503_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2529254.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(3503..4219)
                     /locus_tag="PC503_003298"
     CDS             complement(3503..4219)
                     /locus_tag="PC503_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2529255.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            4384..5109
                     /locus_tag="PC503_003299"
     CDS             4384..5109
                     /locus_tag="PC503_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2529256.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASFLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            5169..6761
                     /gene="hcp"
                     /locus_tag="PC503_003300"
                     /gene_synonym="priS"
     CDS             5169..6761
                     /gene="hcp"
                     /locus_tag="PC503_003300"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF2529257.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            7133..8038
                     /locus_tag="PC503_003301"
     CDS             7133..8038
                     /locus_tag="PC503_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2529258.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            8162..9115
                     /gene="msrA"
                     /locus_tag="PC503_003302"
     CDS             8162..9115
                     /gene="msrA"
                     /locus_tag="PC503_003302"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF2529259.1"
                     /translation="MIKLATFSGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            9268..10398
                     /locus_tag="PC503_003303"
     CDS             9268..10398
                     /locus_tag="PC503_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529260.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(10515..11483)
                     /locus_tag="PC503_003304"
     CDS             complement(10515..11483)
                     /locus_tag="PC503_003304"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF2529261.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
BASE COUNT         4531 a         1322 c         2008 g         3770 t
ORIGIN      
        1 atttgaataa aaagaatgta taataagtat aataatttgt atttattatt gggaaaggaa
       61 aatgttaata tggatagtta taaacaactt aaagctaaaa taccctgtaa ggaaacaggt
      121 atagaaataa agaggacttt atgtgatatt tgttcgccag gagtacattg tggaattgat
      181 gcatatgtta aagatggtaa agtaataaaa atagaaggta caaaagaaca tccaatgaat
      241 aaagggttgt tatgtaccaa aggtctttgc aatagagaat atatctatag agaagataga
      301 ataaaaacac ctctaaaaag aattggaaaa agaggtgaag gaaaatttaa accaatatca
      361 tgggatgaag cttatagaga aatagcagaa aaattaaata gagtaaaatc tgagtatgga
      421 gcaaagcatg tagctttttt tacgggttat ggaaagtggt atagaccttt tttacaaagg
      481 tttgcatctt catttggttc acctaattat ggtacagaat ctagttcatg ttcaacatca
      541 gcacagatgg ctggaaatgt tgctactgga agaaacttta caatgcaaga tatggagaat
      601 gcaaaaactt atttagggtg gggatttaat ccatactact ctaaattttt aaatagtgtg
      661 aatctaataa aattaaaaga aaaaggtcta aaatttataa ttgtagaccc tagaataaca
      721 ccgacaactc aaaaactagc agatttacat ttaagaatta aacctggaac tgatggagct
      781 ttagctcttg gaatggcgaa tctatttata caaaaggatt taatagatag agaatacata
      841 gaaaagcatg tacatggatt taatgaatat aaagaatatg taaaattatt tgatttagat
      901 actgtaagta gaattacagg agtttctaaa gataatatag taaaagctgt tgagatgttg
      961 tcacaaggtc cattttgtat aaatgaaagt gcagctccaa tagttcatca tcaaaatgga
     1021 tttcaaaatt atagagcaat gatgtcttta tccgctataa caggtaatta tgatagaata
     1081 ggtggaaaca taccaaaaca agattacttt gctggtaaga taggtggatt ccaaacacta
     1141 gaaaaagagt ttgtaaaaga agttctacct aaaaatataa atgaaagaat tggtggagaa
     1201 agatttcctc tatggaatga aatggtgact caatttcaag ctatggattt acctaggcaa
     1261 atagaagaaa agacaccata tgaaataaga gctttgtttt gtcatgggat aaatgctaga
     1321 atgtttccta attcagggag actttttaaa gcgttgaata gtgtagattt ttttgtgaat
     1381 atagatttat ttatgacaga tacatcaaaa tatgcagata tacttttacc tgcatgtaca
     1441 tcatttgaga gagaagaatg taagagttat ccaggagggt atattacata taccaaaaaa
     1501 gttattgata aattatacga ttcaaaatca gatgtagaaa tactttcaga tttagcaaat
     1561 gctatgaata tagatgatga tttattaaaa gcaggttatg aagcaagtgt aagacatatg
     1621 tttaaaaata catgtgtaga tgtagataaa cttaaagaaa gtgatttacc attaaaatgt
     1681 aaagatttta agccatatat agtaggttca tatacaagag aagggtatga tactagcact
     1741 tctaggtttg aattaaaatc tacaattatt gaaaaatata aagattttgg gctggatgca
     1801 ctaccaacat atagaggatt taatgataat atagatgatg aatatactca tttattgaca
     1861 tcaggagcaa gaatttcaaa tgcactacat tcaagacttc atgacatcaa actttcaaga
     1921 atattaaaaa atgaagctaa ttgtgatatt tctagcttag atgcaaaaga attgggtgtt
     1981 atcagtggag attatataaa aataactact aagataggaa gtttggatgt aaaagtcaat
     2041 gttactgata gagtcttata taagaatata catatgtatc atggatatag agaagctgat
     2101 ataaatagta ttatttgtga taattttgac ccttatagtg gattccctgc gtatagaagt
     2161 tgtaagtgta agattgaaaa aatgaataga taaatggaga gatataatga aaagtttatt
     2221 taaatttaat aaagaattat gtacagcatg tggagcatgt ttgcttgcat gtatagacca
     2281 aaatgataat aatatagaca atggtgaact ttttagacat gtatttacaa tagaggaagg
     2341 tgaaaatata gaatattttt cattagcatg tatacattgt aatgagccaa aatgtttagg
     2401 tgtatgtcct aaaaattgtt ttaaaaaaga agaaggattc attgtattag acaatcaaaa
     2461 ctgtataggg tgtaaacttt gtgaaaaagc ttgtgaatat ggagccttaa tttatggaaa
     2521 tgatggtaag gcaaataagt gtaatggttg tattgagaga tataagtgtg gtatggattc
     2581 accttgtgta atggtatgcc ctacaggagc attaaaattt aataaataat tgtattaaat
     2641 tgctatacta cttttaaata attgtgttaa gaattatttt ttgatatact tttgtaatat
     2701 aaaatgtaaa taaaacaaat acaaagtata taaaatatat ttttagaata aagtgtgctt
     2761 tagattaaat ttagaaaaat aaattagaca ggagaactta atatggtaaa agtattagcc
     2821 tttatgggca gtccaagaaa aaaagggaat gtagacacaa tacttgatga gataataaaa
     2881 ggtgtaaatg ataataatgt tgaagttaaa aaatattatc taaatgatat gaatattaaa
     2941 ggatgtcaag gctgtctata ctgtagaaaa gttcctactt gtgcatttaa agacgatatg
     3001 attgacatat atgaagatat aaaaagtgct gaatatataa taattggttc gccagtatat
     3061 atatgtcagg tatcagctca aacaaagcta cttttagata gattgtatcc tttaacagag
     3121 ataaataagt ctaaacatat acctaggttt ggtcaaaaaa agttaatcat ggtctatact
     3181 caagcagctc ctatttcgtt tttatttaaa aaatatttta agtatactgc aaaacattta
     3241 aagggcatgg gattaaatca ctacaaaact atagttgtaa ccaaagcatt tgaaagaaat
     3301 tccactaaaa aaaattttaa ggtattgaaa aaagcctata aacttggaat gaaaatagcc
     3361 attgatatca atggatagat aaaagtttaa tttatagtat agctaaagga gcattaatta
     3421 ttaatactcc ttttttgtat aaaggtttct agaaaataac taataaaaaa caatattatt
     3481 tgaatacaga tattatacaa gcctagatat ctaacttgtt ttgaaaataa aagatttcaa
     3541 atttattttt gttaaaagat aacaagcctt catctcgcat cttgccaagc tctcttgaca
     3601 tagaacttct gtcaacacat aaaaaatcag ccatttcatt tcttgaaaag ggaattgtaa
     3661 actggtggct acctgtttgt tctatctgtt ttgaaaaata cataagcaat ttctcgcgag
     3721 ttgttttacg agaaagtaat tctattttat tgtgaagtaa aatgtttttt tcagctatta
     3781 attgtagcat attttcaaca agcctattat gaaatacaca tgcagatgaa caaataccag
     3841 ttacactttt aaactttata aataaaactt cgcaagaaga tgttgtggtt actgtaacat
     3901 tacttttatg tagtctagta catgcgaata cctctccaaa taaatctcca ggcaagagtt
     3961 cagctacaat attcctattc ccttcgatat cttcctttat tatatgagca cttcctttaa
     4021 gcataattcc aatagaagta acttcacttc caacagagaa tattatacta tcttttgggt
     4081 aagtcttatc tacaacacct aaacattcca acatttcttc aagttcatca cttttaattc
     4141 cttcaaatag aggaattttt ttaagtaagt ctatatgctt ttctaaaaat tttttcaaat
     4201 aatcacttcc ttgttgcata tgcaaccgat aatttgtttt cattgtacta tactaagttt
     4261 ataaaagcaa ggggatataa aaatcctact acaagaaatt tgaaataaag aaatataggt
     4321 attaaaaata aatatataag aaatcaatac tttaaattaa aaaaatttta tgaggtgata
     4381 taaatgatga gaaaaataat taaaattgat gaggaaaagt gtaatggttg tggactatgt
     4441 gttgaagctt gtcatgaaga agctatagga atggtaaatg gaaaagcaaa acttttaaga
     4501 gatgactatt gtgatgggct gggagattgt ctgccaactt gtccaacaaa tgcgatttca
     4561 tttgagtata gagaagcagc agaatatgat gaagctgcag taaaagcaaa tatggaagca
     4621 aagaaagcac aaaagaaaac tttagcatgt ggatgtccag gttctcagtc taagtcaata
     4681 aatagagagg tttcaaatag tacgtctata agcaatgata tagtagagat aaaaggttct
     4741 caacttaatc aatggccagt acaaataaaa ttagtaccaa ctaatgcatc atatttaaag
     4801 aatgcaagtt ttttaatagc agcagactgt acagcgtatg catatggaaa ttttcataat
     4861 aaatttatga aaaataaggt tacattaatc ggatgcccta aacttgatga agttgactat
     4921 gctgaaaaac ttacagagat tttaaaagaa aatgatatta aaaatatagt agtaacacgt
     4981 atggaagttc cttgctgtgg tggtatagta aatgctgtta agacagctct acaaaatagt
     5041 ggaaaaatga taccatggca aatagttact atatctgtag atggaaaaat tgtagatgga
     5101 gaaatttaat taagtgaatt atagaaaaat ataataaatt ttaataaata aaaagggagg
     5161 aataaaaaat ggaaaaaatg ttttgttttc aatgtgaaca aacagcagga ggtaaaggtt
     5221 gtactataaa tggtgtctgt ggtaaaaagg ggggtacagc taacttacaa gacgaactta
     5281 caggagtgtt gattggtctt tcaagagcaa ctattggaaa taagaataga ccaacaagtg
     5341 aaacagataa aattatgata gaggggctat tcactactat aacgaatgta agttttgatg
     5401 atgaagctat aaaaagacaa attgaaaaaa ctgaggtaga aaaaagtaaa cttgtaccta
     5461 gatgttcaga ttgttcaaca acttgtaata gaaatgataa ctatgatatg aaggatttat
     5521 ggaatgataa tgaggacata cgttcattaa aatcattaat cttatttgga ttaagaggta
     5581 tggctgccta tgcatatcat gcaatggtac ttggttatac agacaaagac gtaaatgaat
     5641 ttttctatga aggattaata gcagttggag gagacttgtc tattgacgaa cttttaggtc
     5701 tagttatgaa aactggagaa ataaacttaa aatgtatgga attgcttgat agagcaaata
     5761 ctgaaactta tggaacacca gaaccgactc aggtatctat gaaaatcgag aaagggccat
     5821 ttattgtagt tacaggacat gacctttatg atttacacaa attattagaa caaacgaaag
     5881 ataagggtat aaatatatat actcatggtg agttattacc agcacatgca tatccaaaac
     5941 taaaagaata taaacatcta aaaggtaatt ttggtacagc atggcaaaac cagcaaaaag
     6001 aatttgataa tattcctgct ccaatattat ttacaacaaa ctgtttaatg cctgttaaag
     6061 atagttatag agatagagta tttactacag aagtagttgc ttatccaggt atggttcata
     6121 ttgatgaaga taaagatttt tctagtgtaa tagaaaaagc tcttgaactt ggaggatata
     6181 gagaagatgt tcatatgact ggtattaatg gaggagatac attaactact ggttttgcaa
     6241 gaggtacagt ttcatctgta caagataaag tagtagatgc tgtaaagagt ggagctataa
     6301 gacacttttt attggttgga ggttgtgatg gtgcaaaacc tggaagaaat tattacactg
     6361 aatttgtaaa acaagctcct aaagacactg ttatattgac acttgcatgt ggaaaatata
     6421 gatttaatga tttagacctt ggggatatag gtggcttacc tcgtttaatg gatatgggac
     6481 aatgtaatga tgcttatagt gcaattaaag tggcagtttc attggcaaat gcttttgaat
     6541 gtggagtaaa tgatttgcct cttagcatgg tactgtcatg gtatgagcag aaagctgttt
     6601 gtatacttct tacactactt catttaggta tcaaaaatat ctatataggg ccttctttgc
     6661 cagcattctt atctaagaat gtattagata tattggttga taaatttgca ttgacaccta
     6721 tatctactcc tgaagaagat atgaagaaga ttttaggata aataaacata tctatactta
     6781 aagatattta tagttaaaat atttttaagt atgccacaat taagataagg ggttaaactt
     6841 aaaatttgat taaaaaatca attttgagat gaccctttat ttattttttg taataattga
     6901 aaaataaacc tgctttcagt atattctttt taagaatctt tgtattaaat ttataatact
     6961 tagatatata atatcttata tattttattt taagtattaa aggtttgaat gtaacttaaa
     7021 tattaaaaga ggaacattgt aatatgtaac ttgcataaaa tatatatact atagtgaaat
     7081 tattttgatt aaaatttaaa atataaggtg ttttatgtgg gggtatatgt atatgaaaaa
     7141 ttctaatttt aatatattgg catttgatgg tggtggatta aaaggggcat tgagtatatc
     7201 catacttgag aggatagtaa aagagtatcc aaatctatta aacaatataa atatgtttgg
     7261 aggtacatct acagggagtc taattgcact agggcttgcg tatggtgtaa gccctaaaga
     7321 gataaaagaa ctttactcaa ttgaaaattc aaagtatatt tttaataaaa gttatgcaga
     7381 aatactcaga ccaaagtatg aaaacaaaaa cttaaaagaa gttttattaa gtatatttcc
     7441 agaggaacta gaattaaaag atttaaataa attagtaatg ataccaagtt tttatatagg
     7501 aaatgaggaa aatgcatgga aaccagtgtt ttataacaat atgccaaatt cttttacaaa
     7561 gactagcaaa gttgtagatg tagcaatggc aagtagtgct gctccggtat tttttccaac
     7621 atataatcgt catgttgatg gaggaataat agcaactgac ccgagtttag cgtgtataat
     7681 tcatgccatt gacagtggat ttaaacttaa gaatacaaga cttttttcaa tagggactgg
     7741 atatgtatat aacagtataa aggcagatac taccgaatgg ggagctattg actggataat
     7801 taataaagaa cccgatttac caattatatc tattacctta gaaggaaatt ctcaaatgag
     7861 tcagttattt tctcaaaaac ttcttggaga taattactat agattaaatc ctaagatgga
     7921 aaaagatgta gctatggatg attgtgatgc attagaatat ctaatgtctt taggagaaaa
     7981 ttgtgatata aaagatgctt ttggatggat aaagaaaaag agcttttata gaaattagat
     8041 tcaatttgca attgtatttt tacacatgat ttcattgagt aggtaaaaat aataaaatgc
     8101 agattattaa gttacttctt agggaataaa taaagtataa tttatttaag gagtgatgaa
     8161 aatgataaaa cttgctactt tttcaggtgg atgtttttgg tgtatggtaa aaccttttga
     8221 taagtatgat ggagttatta aagtagtttc tggatataca ggtggtcatg ttgaaaaccc
     8281 tacatatcaa gaggtatgct caggaactac tggtcattta gaagcaattc aaataacata
     8341 tgatgatgat ataataagtt atgatgaact tctaaatatc ttctggaaac agattaatcc
     8401 tacagatgat ggtggacaat ttggtgatag gggaactcaa tataagactg ctatatttta
     8461 tcatgatgaa gaacaaaaaa atatagcttt agagtcaaga gaacatctgg aaaatagtaa
     8521 aatatttgat agtaaaatag tgactgatat aattccagca actaaattct acgaagcaga
     8581 agaaaatcat caggattatt ataagaaaag accattaaac tacaatatgt attataaagg
     8641 gtctggaaga tataattttg taaaaagcca ttgggatgga aacaatataa atagggaaga
     8701 gttaaaaaag actctaactc ctatacaatt tgaagtcact caaaatgata tgacagaagt
     8761 accttttgaa aatgaatatt atgacaataa caaagaggga atttatgttg atattgtaag
     8821 tggagaagtg ttattttctt caaaagataa atttgattct ggatgtgggt ggccaagttt
     8881 ttcaaagcca gttatagata aatctatcat tgagagaagt gatttctcac aaggtatgta
     8941 cagagttgaa gtaagaagtg ctaaaggaaa ttctcattta ggtcatgtat ttgatgatgg
     9001 tccaaaagaa cttggaggtt taagatattg tataaattct gcttctctta aatttatacc
     9061 aagagaaaat atggaagctt taggatatgg agaatattta aaactttttg agtaattagg
     9121 aatatttatt ataaacttat ctaaaaggtg aaaatataaa aaaatatttt caccttttgt
     9181 ttttttgtca ataatatgat aaattattaa ttgtaatctt atttatacca atagattaag
     9241 aatttaattt tgaaagagag aaaacaaatg aatttaaaag actttaatgg aaagagatta
     9301 aaatcagcta gaatttttag agcaaagacg atagaacagt tgtctaaaga aactaaaata
     9361 aataaaaaag atttaaaagc ttttgaggaa aataagtatg taccaaatat agaaaataca
     9421 ttaaaattat ctaatatatt aaattttcca aaagagtatt tttataaaaa tgaaaatata
     9481 aatatcgttg tagaggatag ccactttaac cctcaatcta aactacctag agtagaagag
     9541 atttcttata gagaaaaaat aattataata cataaaatat attcatttat ggagaattat
     9601 attaagtttc caaaagaaaa cttgccaaat agaaaagtaa tgtcagatat taatataaat
     9661 gatatagaat ctcttgcata taagactaga gagttttggg atttaaatag tactccaata
     9721 gtaaatatgg taagtttgtt agagtctaaa gggattataa tatcaggtat gaatgtagat
     9781 agaaaagggg caactatctt tactcaaaaa cagagaatta gtaaagaatc taaatatcta
     9841 atatctctgg gtaatgacaa aaagtcagca tcaattagaa attatacttt ggcatgtgag
     9901 cttggatata taatatcaag tgaattaaga ataccaagta agcaattttc agaagatgag
     9961 tatgcctgtg catttttatt gccaaaagag agttttttaa aagatttgac tcatccagaa
    10021 gatttagatt attatgtaga actaaagaaa aaatggattg tacctatatc tgctatgatt
    10081 tttagagcat ataatctaga aaagataaat tacaaaaaat acaattatct tatgaatgaa
    10141 atggataaaa aaggctggtt gatagaagaa ccactagaca aaatgaaagg ttcaagccca
    10201 acgtatttaa aaagagcagt tgaattattg atagaaaata aaataatgag tgtaaatagt
    10261 atagtatcaa gtttagagga atttggaata aatctttatc cagaagactt agaattattg
    10321 atgggattga aaaaaggatt gttatctcaa gaggtaaata aaaaaagtaa agttataaaa
    10381 tttgatggta aaaaataggt ttatatttta gtattaaaat taaaagcagg tacaaatgat
    10441 ttaaacatta acttagttaa aggtcttttc aataagtcat ttacctgctt ttagtgtaag
    10501 aaagaatatt gaatctaaag tgtttttgaa agtgcaatat attcccttaa aacagaacaa
    10561 gatttattaa attcattttg ctcatattca gtcatattga tttcaataat ttcttcaata
    10621 ccatcttttc ctataacaca tggaacacct gcaaatacat ttctttcgtt atattgacct
    10681 tctagtaatg tagaaactgg aagaactttt ttctcattgt gtagtatagc ttttacaatt
    10741 tctactaaag cagtacctat accaaattct gtacaatctt taccatttat tatacttatc
    10801 cctgtttttt tatttttttc aactattgat ggtaagtcta aattgctata agtacttggg
    10861 ttgtctttta tcatgtctaa gattggttta ccaccaattg aaacatgaga ccaaggaacc
    10921 atttgagaat ctccatgttc acccatagaa taagcttgaa ttgattgttg agcgattcca
    10981 gtttcttcag ataaaatcct tctaagtctt gttgaatcta aagctgttcc agttccaatg
    11041 actttgtttt taggaaagcc agatttttcc caaatataat ttgtaactac atcaacagga
    11101 ttagatatga ctacaaatat accatcaaag ccagaatcaa ctatgggttt tactatagat
    11161 tttatcattc caatagttgg tcttagtaaa tctaatctag ttgtgttttg tctacgtaaa
    11221 ggcccttctg aagagtctgc aacacttatc actactatgt cagaatcttt acagtcagaa
    11281 aaagttcctt tttctatatg tactttatgt ggcagatatg aaactgcatc agctaaatct
    11341 aaagcttgag cttttgattt agattcatct atatcaatca taaagagttc atcacaaact
    11401 ccttgagtta ttaaactaaa tccacaatga gaaccaacat gccctgaacc tacaatagat
    11461 atttttcttg gctttattgc cattttaaat cactccccct aaaataacga tacattgaaa
    11521 attatagatg ttattaaaag ctgtttttgg atattttaat attctattat ttcagaaaat
    11581 ttatttaata tgattttata ctaaaatttt taaaaaagca atgttaatat a
//
LOCUS       DAMJWC010000099        11342 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMJWC010000099 DAMJWC010000000
VERSION     DAMJWC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.103"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            105..713
                     /locus_tag="PC503_003305"
     CDS             105..713
                     /locus_tag="PC503_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF2529262.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            1040..3937
                     /locus_tag="PC503_003306"
     CDS             1040..3937
                     /locus_tag="PC503_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2529263.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDEESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKVKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            4258..4470
                     /locus_tag="PC503_003307"
     CDS             4258..4470
                     /locus_tag="PC503_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2529264.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            4483..4704
                     /locus_tag="PC503_003308"
     CDS             4483..4704
                     /locus_tag="PC503_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2529265.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            4804..6960
                     /gene="feoB"
                     /locus_tag="PC503_003309"
     CDS             4804..6960
                     /gene="feoB"
                     /locus_tag="PC503_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2529266.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            6986..7138
                     /locus_tag="PC503_003310"
     CDS             6986..7138
                     /locus_tag="PC503_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF2529267.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            7318..8028
                     /locus_tag="PC503_003311"
     CDS             7318..8028
                     /locus_tag="PC503_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2529268.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            8113..8883
                     /locus_tag="PC503_003312"
     CDS             8113..8883
                     /locus_tag="PC503_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529269.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            8876..9607
                     /locus_tag="PC503_003313"
     CDS             8876..9607
                     /locus_tag="PC503_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529270.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            9641..10600
                     /locus_tag="PC503_003314"
     CDS             9641..10600
                     /locus_tag="PC503_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2529271.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10698..11294)
                     /locus_tag="PC503_003315"
     CDS             complement(10698..11294)
                     /locus_tag="PC503_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF2529272.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         4355 a         1167 c         2039 g         3781 t
ORIGIN      
        1 aaataaatga ttaatccaaa aataaatttg attttagaaa agtaaattga catgtaaaga
       61 agaatatatt aaactaagta taaaaaattt gctgttttgt aaaggtggtg gataatctga
      121 taaagtatat acataaaagt gatgtagcta ttgttgtttt gcatgaaatc tatgggatta
      181 atagctttat agaagatgtt tgtcaaaagt attataaata tggatatgat gtattttgtc
      241 ctgaacttct gggagaaaaa agagtttttc catattcaaa agtccaagag gcatatgatt
      301 tttttataaa taatgttggt tttgatattt ataaaaaagt tgaaaagctt ataaatgatt
      361 taaaatcaga gtataaatat gtatttgttg ctgggtatag cgtgggagca actattgcat
      421 ggagatgcag tgaagattct ttttgtgatg gcataatttg ttgttatggc tctcggatta
      481 gagattacat ggatgtaatt ccaaaatgtc ctaccttatt agtatttgca aagcacgatt
      541 catttgatgt tgattctatt tcttaccaac tttctaggaa acaaaatatc caaattgaga
      601 ttttagatgc aaatcatggt tttatagata gatattcaaa taattattct gatattcaaa
      661 caaaagtatt tactattaaa gaaaaaagtt ttctgtctaa atatttagca tgatttagat
      721 tattataaaa tatatagaaa gatttaatta atctgaaaag tttttatgac actattgata
      781 tttaaaatat tagtagtgtt attatatttt ttgaaataaa attaatcact agaattatag
      841 tgttagttgt gcttttatga cttataagaa actaatatta gatagtgtat ttaaatagat
      901 aataataaat tcattatagt tgaataagaa tattatatga gaatattgca atttgatata
      961 tttaccatta caataaaagt agttacaact agaaaacgaa ataagttaaa gtaagttggc
     1021 aaattggagg tttttaaata tgaaagcatt taaaaagcac ttcttgatac tttctttgat
     1081 atttttactt attatatcat gttttaacaa tatactatgc tttgctgatg agtctgaaaa
     1141 ttcaaaaaaa ataagagttg gatattgtga tgactacgga ataatatcct catcaaaaga
     1201 gcattcttat acaggatatg gttatgatta tctaagagaa atctcaaaat atacaagatg
     1261 ggaatatgaa tttgtaaaag ggtcttggga agaatgttta gacagactag aaaagggtga
     1321 aatagactta ctcggacctt tacagaagaa tgatgaaaga aataaactat ttaattttcc
     1381 taaactaagt tcaggatatg aatatagtgc actatataca aaggatagta acaataatat
     1441 gttttatgaa gatataagtt cctttaaggg aatgagagta gctgtactta gaggaaactt
     1501 tcataatact gcatttgaga agtatagaga agaaaataat ttttcagttg aatatatata
     1561 ctgtaattct attgatgaat taattgagtc cgtcaatgaa aaaaaggcag atgcatttgt
     1621 ttgtggaagt attataaatg ctaaaggaat gaaaatagtt agcaaatttt cagtagaacc
     1681 tttttatttt gctactgcaa aagataaacc taatttagta aaagaattag attatgcttt
     1741 aaaagaatta aaaataaatg atatgtatta tgagttggaa ttatataaaa aatatttcaa
     1801 aagagaggtc aataattcca tagcatttac tcggcaagaa atgaatttta ttaaagcaaa
     1861 cccaaaactt actatggtat atgattcaga gtggtctcct gtagagtatt atgatgaaga
     1921 aagcaattca tttaaaggta taagttccga tttaatgtca attatatcaa aaaaatgtgg
     1981 tataaaattt gaatatatta aaacaaaaaa ttataatgag agtcttgatt acataaaaag
     2041 tggtaaggca actatgctat gtggctcaat caatgaaaat gataaggtaa aacgatttaa
     2101 tatgaaattg acaaatccat acataaatat tccaatgatt atggtaggaa aattggatac
     2161 caatctcaat aatgatttaa atattgcttt aactagtagt tataagtcta ttgattctta
     2221 tatagaaaag agttttgaaa atgctaagac aacatcttat aagagtgtag aaagttgtct
     2281 aaacgctata aatgaaggta aagcaaactt aatgatactt agttcttatc agtttgatga
     2341 acttttaaga gaaggaaaga gtgagaattt atctgttata tctgttttag atacaagcta
     2401 tgggatgcgt ataggggtat caaataaaac tgaccctata ttagtgtcta ttttaaataa
     2461 atcaatagac aaaattactg aagaagaatt aagtgattgt atatattcta atactattga
     2521 caaaccttat aaagtaccat ttggtgtgat ttttaaagaa tattcaatac aaattatttc
     2581 ttttgtatgt attttattct taattgctat taaatatata atttataata aaaagaagaa
     2641 agaggattat ctaaggaaga tagcatatac agacccattg acaggagcag atagtataga
     2701 taaatttaaa ataaattcta ataaactgtt tgctaagaat aatccagaag aatatgcgtt
     2761 gttttatata gatgttgaca aatttaaata tataaatgat atgtttggat atgatatggg
     2821 aaatgatact ttgatacata tatcaaatac tattgcaagt gaattaaagg aagatgaaat
     2881 ttttgcaaga gtttctgctg accattttgt tcttcttatt aagtataaga cagatgatga
     2941 tattaaaaca aggttaaaca atatttacaa taaggttcaa atacttagta atcctaaaat
     3001 aaactattat aaattgattt tagattgtgg tatatataaa ataagtaaaa gtgataatga
     3061 cataaatact attatggata gagctaatac tgcaagaaaa actataaaag gtggtcataa
     3121 aaattcattt gctttttacg ataaggaaat gcacaaaaaa atattaaaag agaaagaaat
     3181 tgaaaattca atggtagatg ctcttaataa tggagaattt attgtttatt ttcaacctaa
     3241 atatagcctt tcagattatc aaattatagg ggcagaggct cttgttcgtt gggataatcc
     3301 acaaaaaggt ctaataccac caatagaatt tattcctgta tttgagagga atggttttat
     3361 tgtaaatatt gatttctatg tatttgagga agtgtgtaaa aagattagag aatggatgga
     3421 tgaaggacaa aaagtagtac ctatatctgt aaacttgtct cgaatgcatt ttgtaaatag
     3481 taattttata gaggagttta aattaattgt agataaatac aaaattccga caagacttat
     3541 agaattagag ctaacagaaa cagcagtatt agataatata gaaggattac ttgatacaat
     3601 gaacaatttg aaagaaaagg gatttgtaat ctctatggac gattttggta caggatattc
     3661 ctctcttaat cttttaaaag aattgcctgt tgacatatta aaactagata gagcattttt
     3721 tacagaaaaa gatgagagta ataatgaaaa aattgttata tctaatgtca ttaaaatggc
     3781 aaaggaactg aaaatgaaag taatatcaga aggtgtagag actatttcgc aagtagaatt
     3841 tctaaagcaa attgggtgtg atatggtaca aggatatttg ttttctaagc caatgcctgt
     3901 aaaagagttt gaaaaaatcg cttttaaaaa agaataaagc aatgtgtaaa taatgacata
     3961 tataataaag gtgctttaat attagttgag tatactattt tagagcatct ttatttttgt
     4021 attaattttt acgattttat taataaaata aatcaaatga gaaaaaaaat caaaagaata
     4081 caataatcac ttgcaaaaaa tatactattg tgatagactt aaatcaaaat taggaattgt
     4141 aaaaagaagg aaaaaatagg atgttatttt aatagattaa gatttaaggt attgtaattt
     4201 atatataaga taacgattgc ttgtagattt aaattacttt aagaggaggg atattatatg
     4261 atgccattga tattatcaaa tacaggtgaa gaagtagtta taaagaaaat ttcgggaagt
     4321 gataagacga ggactttttt aaatagtata ggttttgtag tgggtacaaa tgttaaaata
     4381 gtttctaaga tagatggtaa cttaataata gacgtaaaag atactagagt tgcattagat
     4441 aaaaaaatgg caagtagaat aataatatag ggaggtaatg acatgaacag actgaaggat
     4501 attaagtgtg gagagactgt aaaagtcaaa aagttagagg gagaaggagc tacacgaaga
     4561 cgtataatgg atatggggat tacaagaggt gttaatatat ttataagaaa agtagctcct
     4621 cttggtgacc caattgaggt aacagtcaga gattatgaac tatcaattcg taagtcagat
     4681 gcagaaaaaa ttattgtgga ataataaaga ttaattagag tagggttaat gtaattatat
     4741 aatgagaatg attttctgta tcacaaacag tgatgtattt aaataataat ggagggaatg
     4801 gaaatgtcaa taaaaatagg tctcatagga aatcctaact gtggtaagac aacaatgttc
     4861 aatgggctta caggctcatc acaatatgtt ggtaactggc caggagtaac agtcgaaaaa
     4921 aaaggtggaa aattaaaagg aaataaagat gtggaaatag tagatttacc aggtatttat
     4981 tctttatctc catatacatt agaagaagta gttacacgta attttatgct agatgataag
     5041 ccggatgcag taataaatat tgtagatgca tcaaatatag agagaaattt atatcttaca
     5101 actcaagttt tagagctagg tataccgacc gttatagctc ttaatatgat ggatattgta
     5161 aataagaatg gtgataagat aaatattaaa gaactatctg aagttatagg ttgcccagtg
     5221 gtagaagtaa cagcagttaa aggtcaagga attatggagg ctgctgaaaa ggcagttgaa
     5281 cttgcaagta gtaacaataa attaaatttc aaattaccct ttgttgatga aagtaaggat
     5341 gcaatagaaa aaattgaaaa aataatagaa gaaaagactc catatataga tgtagaaaca
     5401 cgctggttag ctataaagct atttgagaga gatgaaaatg ttatacaaaa acttgatatt
     5461 tctaaaacaa tattgaatag tattgaagaa ataactagaa attgtgaaga tgaattggat
     5521 gatgatagtg aaagtataat aacagccaat cgttatgaat ttattagttc aataatttca
     5581 agtataataa agaagaatcg aaaaggtaag gaaactgtat cagataagat agataagatt
     5641 gtaacaaatc gtatactagc attacctatt tttgcactta taatgtgggg agtttactat
     5701 atagcagtaa gttcattggg tactatagca actgattgga caaatgatgt actgtttgga
     5761 gaaattattc aaggcaatgt aagtaatttt ctagcttctt taaatgtagc agagtggtta
     5821 caaggacttg tagttgatgg tctaattggt ggagttggag cagtactagg atttgtacca
     5881 caaatcatgc ttttattctt attattatca atattagaag attgtgggta catgtcacgt
     5941 gtagctttta taatggatag aattttccgt aagtttggtc tttcaggaaa atcatttata
     6001 ccaatgctta taagttcagg ttgtggagtt ccaggagtta tgtcaactcg tactatagag
     6061 aatgatagag atagaaaaat gactattatg ttaactacat tcattccatg tggagctaag
     6121 attccaataa tagcattatt tgcaggggca ttatttggag gtgcttcatg ggtagctcca
     6181 tcaatgtatt tcttaggtat tgcaatgata atcatttgtg gaattatatt aaagaaaact
     6241 agtttatttg caggagaacc atctccattt gttatggaat tacctcaata tcatattcca
     6301 agtgcaaaag gtgttttaat acatatgtgg gatagaggaa aagcatttat aatcaaagca
     6361 ggaacaatta tatttgttgc ttgtggagta atctggttct tacaatcatt taattggtca
     6421 ttacaaatgg tagatgctgg agatagtata ttagctagct taggaaatat agttgcacca
     6481 atatttgctc ctcttggatt tggaaattgg caatcatcag tagcaacagt tacaggtcta
     6541 gtagctaagg aaaatgtagt tggaacattt ggagttttat ttggtatatc agatgcaaca
     6601 gagcaagacc caacacttct tgcttcagtt gcaagtatgt ttacagtagc tagtgcgttt
     6661 gcatttatgg catttaatat gctttgtgca ccttgttttg cagctattgg agccataaaa
     6721 agagaaatgg gttcatggaa atggacatgg attacattag gattccaaac tttaacagcg
     6781 tatataattg ctcttcttat aaatcaagtt ggaagtttag ttttaggtac tggaggaagt
     6841 attgctgggg caataatatc tatatttata gcagtagcag tagtctttgt agttttaact
     6901 tattcaaata aaaatatgaa aaaagaaaaa atgggtaaat taagttatat gaaaaattaa
     6961 ttcatataaa taaggagtga tgaatatggc tacatttatt atagcagcta ttgtagtagt
     7021 attaatggca ctagctgtaa tgtatatggt taaaaattca aaaaagaatg gtagcagttg
     7081 tggatgtggt tgttctggat gctcaagtag taagagttgt catagcgcta agagataaat
     7141 aggataagag cctgataaaa agttaaattg ctttattatc aggttcttat tttttgtata
     7201 aataacaaat ttcatatttg aagtaggtta gactatgctg taattttact gtataattat
     7261 atataaatat atgattagga gggattattg ctaaattaag caatataagt gaatattatg
     7321 tttaaatttg atgttacaaa cgagcttatg tgtatagcaa ggggaagtgg taaatttttt
     7381 gcaaaaaaag gtgctatggt agcctttaaa ggaaatttta attttgaaaa attgctgtta
     7441 ggtccaagta atggcggtgg attgggaaga gcattattag gtcatgttca gaggtcattg
     7501 acaggagaac aaatgccaat aatggtggtt gaaggtgaag gtgaaattta cctagctcaa
     7561 aatgcttacc atgtagatgt aatatcaatt gacccaggtg attccattta tgttgagagt
     7621 gaaaacttat tggcattttc tgaacaatta aattacagtg taaaattgat tggttcaggg
     7681 gtaatatctc aaaaaggtct ttttactaca catttagtaa ataaaacagg tcaaaatcaa
     7741 gatgttgcta taataacaga tggtaatcct ctaattcttg aaggaccttg ttgtgttgac
     7801 ccagatgcat tagtagcttg gactggaaga gaaccatatc ctaaagtatc aaaactatca
     7861 tggaagactt ttattggtca gacttcagga gaatcttatc atatggaatt tgttgaacct
     7921 ggacaaatag tcattataca accatctgaa agattgtctg gcttaaaaac agattctaca
     7981 ccttctgata gaatgagttc aggtggatta agacttggca tagattaaat cttatgatat
     8041 agcttaatta ttatttaaga tattaaaaaa taaaaagggt agcagggata gatatgttaa
     8101 aaggagtttt atatgtttga gaaaattcat aaaaggctta aaggatatta tattttttta
     8161 ataattttaa ttttatggaa gatagtatgt gttttgggta tatggagtag ctatattctg
     8221 cctcctcctg aaatagtctt agatactttt ataaaaatga tatatgacgg ttctattttc
     8281 ttaaatgttt atgccagtgt aagaaggata ttaataggtt ttttaataag ttcattgatg
     8341 gctataccac ttggagtttt atttggagca aataaaaaaa tgtatgaata tttcaaacca
     8401 ctatttgaat ttatgcgaag tacacctcca ctagctttgg tgccaatgct tattttatgg
     8461 tttggtatag gtgaagaatc taaaattata attattattt tggcatcctt ttttccaata
     8521 tttttaaata cattgaaagg tataaaaaat tgtgacaata aattaataga agtaggtaaa
     8581 tcttttaatt tatctaaaaa gagaattttt tataaaataa taatccctaa ttctatgctg
     8641 gatattgttg ttggacttag tttagggctt gggtatagtt ttagggctat aattggagca
     8701 gagcttattg cagcttcttc aggactagga tatttgattt ctgatggaaa agatatgtct
     8761 agaactgatg ttgtattggt aggaattttt gttattggat ttttaggtat actttcagat
     8821 tatctatttt caaagataat aacaaaattt agcaaaggga agcaggttga tttaaatggt
     8881 tagaagtgga tttttgctag agaatatata taagaaatat ttagttgata ataaagagca
     8941 tttagttctt gataatatat ctttaaatat atctagtgaa gagataactg ttatattagg
     9001 tgaaagtgga tgtgggaaaa caacgctact tagaatttta gcagggcttg aaaatgctac
     9061 tagtggaaac gtatattttt ttaataatga taaaaagtgt actccaaaag taggaatggt
     9121 atttcaagaa agtagactta tgccatggct gaatgtaagt gaaaatatac ttttacatac
     9181 tgaaaaagat aatagaaata aagttgattt agacaagtat ttaaaaatga tgaagcttga
     9241 aaagtttaaa aactcatatc caaatgaatt atcaggagga atggctcaca gagtaagtat
     9301 agcaagagca ctttccttca atcccgatat tttgctgatg gacgaaccat ttgcagcact
     9361 agattacttc acaagaagaa aaatgcaaaa agaagttgta aatatccata aaaatactaa
     9421 aaaaggtgta gtatttgtaa ctcacaatat tgaagaagct atggaaatag caaagaaaat
     9481 aattgttttt agtaaaaata aaaggattaa acaatttagt gtcgaagatg aatataatag
     9541 agatttaact aaaaactatt atataaactt gaaaaaagaa atattaaggg aattggggga
     9601 gttttaattg attaaaagaa acaaaaagat tttagcagta atgacatctt taataatggt
     9661 gttggttggg actgtaggat gttcaacaac aaatgataag aaagatgaac ctgcaaaaaa
     9721 agaggctagt ttacctaagg aaataaattt aacttatgta aaatcaccac ttaatgttcc
     9781 tagtatatta gaaaaaaagg atgatttatt tggaaaggaa tttaaaaagg acaatataaa
     9841 agtcaatttc catgaattga caacaggacc agagcaaact caagcattag cagcaggtga
     9901 gctagacttt ttacatgcat taggaggaac gtctgcaata atagctgcat caaatggtgt
     9961 tggtcttaaa attacgaata tttatagccg ttcaccaaaa ggatatatgc ttataactaa
    10021 taatgataat attaaatcta taaaagactt aaaaggtaaa aaaattgtag gtccaaaagg
    10081 gactatactt catcaactgt tgattgctgc acttgctaaa gaaggctata ctatagatga
    10141 tgttgaatat gtaaatatgg atattcctag tgctgcttct gcattagaaa gtaaaagtgc
    10201 tgatgtagca atgcttgcag gtccagtggc attgaaaacg ataaattcag gtgccaaaat
    10261 gattgtaaat ggagaaggat tagtaagtgg aataatagtt actgctgtaa gtgatgactt
    10321 tgctgaaaaa tatcctgaat tagtaaaaag atttatgaag gttcatgaag aaactttaaa
    10381 atatatgaat gaaaacaagg atgaagtgat ggatgttgta tctaaagaag ttggtttatc
    10441 tttagatgaa acaaaagaaa tgtattcttg gtatgacttt agttctaaaa taacggacaa
    10501 ggatataaaa gaattagaag atacacagga atttttgatg tctaatggaa tgcaacaaaa
    10561 gaaaataaat attaaagata tgttgtacaa tcaaaattag aatactttaa aatattaaag
    10621 tggaaaatac acccttattt attatggaaa ctgtatggta aaagagggtg tatttttatt
    10681 attatacaaa aacacaatta aaaacagctt actattttat ctacacttat gtagtctagt
    10741 aattttctca ttttcttacg gtgaagtaaa aacttcgaat atgtgtcctc ggattgtttt
    10801 gtgtcaccat aaactttcca atatttaatc atagaaactt cataattact atatcccata
    10861 aatccaatca catctttaag aggatatcct aaaaaaatac ctatttcatc aggaaaaaca
    10921 tcactcttaa gtttatctac taaatgctct aaataagcat taacattcgt attttgtttg
    10981 tatcctaaaa actttaaaaa gtttactgtt tttttacatt ttaatttttc tgataatgct
    11041 tttttattta caaataagat ttttaatccc tttttttctt tatcaataac tataaaatct
    11101 attttcttac acttatatag atatttataa atatcattaa ttttttcctc tctatttaca
    11161 tcagtaaacg aaatatttat tatttcagca ggtttagagc ctaaaaagac tggacctaaa
    11221 acttctaaaa gccattttat atatgatgat tcaattttat ttttacaaca aaattgtgaa
    11281 ttacaacaag acataaaaga taacctcctt caaatgaaaa ttaatatcaa gtaattagat
    11341 ta
//
LOCUS       DAMJWC010000100        11033 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMJWC010000100 DAMJWC010000000
VERSION     DAMJWC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.105"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(34..666)
                     /locus_tag="PC503_003316"
     CDS             complement(34..666)
                     /locus_tag="PC503_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2529273.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(738..1091)
                     /locus_tag="PC503_003317"
     CDS             complement(738..1091)
                     /locus_tag="PC503_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2529274.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1169..1372)
                     /locus_tag="PC503_003318"
     CDS             complement(1169..1372)
                     /locus_tag="PC503_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2529275.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            complement(1762..1992)
                     /locus_tag="PC503_003319"
     CDS             complement(1762..1992)
                     /locus_tag="PC503_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529276.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1994..2401)
                     /locus_tag="PC503_003320"
     CDS             complement(1994..2401)
                     /locus_tag="PC503_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2529277.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(2761..3210)
                     /locus_tag="PC503_003321"
                     /pseudo
     CDS             complement(2761..3210)
                     /locus_tag="PC503_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3224..4150)
                     /locus_tag="PC503_003322"
     CDS             complement(3224..4150)
                     /locus_tag="PC503_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529278.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            complement(4275..5057)
                     /locus_tag="PC503_003323"
     CDS             complement(4275..5057)
                     /locus_tag="PC503_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF2529279.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5213..5833)
                     /locus_tag="PC503_003324"
     CDS             complement(5213..5833)
                     /locus_tag="PC503_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2529280.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5921..6619)
                     /locus_tag="PC503_003325"
     CDS             complement(5921..6619)
                     /locus_tag="PC503_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2529281.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            6720..7535
                     /locus_tag="PC503_003326"
                     /pseudo
     CDS             6720..7535
                     /locus_tag="PC503_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            8207..8974
                     /locus_tag="PC503_003327"
     CDS             8207..8974
                     /locus_tag="PC503_003327"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2529282.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9302..9979)
                     /locus_tag="PC503_003328"
     CDS             complement(9302..9979)
                     /locus_tag="PC503_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529283.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10129..10446)
                     /locus_tag="PC503_003329"
     CDS             complement(10129..10446)
                     /locus_tag="PC503_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529284.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10468..10806)
                     /locus_tag="PC503_003330"
     CDS             complement(10468..10806)
                     /locus_tag="PC503_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529285.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3665 a         1742 c         1567 g         4059 t
ORIGIN      
        1 aagtaaagtt taatataaat aaattataaa atattaaact aatttatcaa tatttcctga
       61 ttgaatatgc ttaatgtttg attgaatttt tttatatggc caatcccacc atttaatttc
      121 taataatttt gaaattgtat cattattaaa tctctttttt ataatttttg caggtactcc
      181 tccaacaata gaatacggtg gaacgtcatt agtaactact gctcttgttc caataattgc
      241 accatcacca atatttacac ctgacataat tatagaatca taacctatcc acacatcatt
      301 tccaattata atgttaccct tattgtccca agcgtccgtt atatggttga tatcgagttt
      361 ccattcttca taaaagatgg gaaaagtata tgtggatttt gatttcattg agtgatttcc
      421 actagtcatt agaaattttg cattacatgc tattgagcaa aacttaccaa ttattaattt
      481 atcattgttt atagggtaat gatacaatac attgtttttc tcaaaatctc ttgggtcatt
      541 ataaaagtca ttatatattg tgtaatctcc aacttctata ttttcccttg ttattacatt
      601 tttaagatat acagtttgat aatcattact tcttggatat accttatttg aacttggaat
      661 agtcatattt aaatctctcc tttaatatat attatgtttt tgactattcc actactacaa
      721 tacatctctt cacagaatca ctccttgtta agaatcttca taagataatg gcgtcctttt
      781 ttagtgttaa gtcggatatt ctttcttagt ccattctttt tagcgtataa ctgacaaact
      841 gtcattttct taccaatagt gtcaatgcta tcatcaaggt cattttgtat tgctttttcc
      901 ttatccctta atgatatatc atcacgtttt ccctttgggg gtttatcagt aggtacaagt
      961 ttccaagagt aaacaaattg tggtttacca aatgaatata catacttata tgcgtatctt
     1021 ccatcttttc tctggctctc tccagttctt aaaattctat ctttattatc tcgtcttttt
     1081 tcagttgaca tgataagaag ctcctctcaa taaccgaatt gagcttgata cgtcatatga
     1141 atattataac atataaggct caatttcatt agataacgtc aagtgtatca acgattttct
     1201 caaattgttt tctctttatt tgaatgcgat tgctattcat aatgacccag ccagaatcaa
     1261 ggttttcatc agcacgttta cgtaattttt tctctccaat acgaaagtat tttgacgctt
     1321 cttcaatcgt caaggtatat ttttcccaaa taggtacatc agtattgttc atataatgta
     1381 tcactccttt ctatgttcgt agttcagaag tagatagatg gctttgataa gctccattgg
     1441 tatttcaacc aatcccattc ttatggacag aaccgtgtca tacaggtgta tcattatact
     1501 gtggtacagg ttacggcaaa acaaccgttc caaaggttat tcacaaatca ctatatagta
     1561 gctctcttga ttaaggtcat ggcgtatagt atttgttggc tatctgtatc acaaacgtat
     1621 ctatctactt tattcagttg tcaaagaaca gtcggcattg atttgcctat aaaaaatcac
     1681 aatagcttgt gggcttttat agacaaataa ttagtgattc tccatgtacc aaatagcttg
     1741 atacatggag agagggcgag attaagacaa attaaatctc aaaatagcag tgattagttt
     1801 tgttcctagc attcgctttg tttcttcttc tacatgaata tagggatttc cgtattcatc
     1861 aaataaagtt ttctgtgaaa gacgaatgat atagtgttca aaatgtttaa gtattacgtt
     1921 tattgcattt acatcgccat gtacagcaag taaaataatt gtaaaaggta atacttcttt
     1981 agtaggtttc atttcaatgt tcctgcatga gttctttcaa ctcttttagt gcatttgttt
     2041 tgtgataatg tatggtattt tctgctaaat ccatcaatgt tgctatgtca gcatttgtca
     2101 tgttgaaaaa gaatgaaagt agaattatat cttgttttct ttttgtaagt tttccgattg
     2161 cttgcgccat taatacatct tcaattcgta tgttgtagtc gtaagaaacc atacagatgt
     2221 agttagaatc ataatcatct aaaatactca atttacttaa ttctgcaagt gacaaagatt
     2281 cgagagatac caaataatca tttctgcgtt tattttcgtc ataaatatct ctagcatagt
     2341 tacgcaaaac tgttttacag aaactgtcga attgatgttc aattgtcttt tcatcaacca
     2401 taagatttca ccctctttcc atcgcaagga gttaaataac cttgcttact cctatcacgg
     2461 tgggagggcg ttaaatcttc gataaatttc aaaaaaaaga gaaaaaaata cacactctgc
     2521 ctatagggca aaaatgtgta ttctttaaaa cgtatttaat ttatattggt tgtaagccac
     2581 caccatattg atgtatggaa atatgcattg gctagctttt cataaaaata caaagatgca
     2641 taagaaatta atagagggga aaaacttatt ctgttattaa aaagtaggtt aattctaata
     2701 aatgctattg cggtcgaatt aaactatata catggcaatc aatcatgttt ctattcttta
     2761 ttatgaattg tgacagtatt cttcaatctt aaagccacat ttttccaata ctttacttga
     2821 ctctctattg taggaatata cattagcatg aattttgtta aggttgtatt tttcaaaggc
     2881 aattttgcat atttctttta ctgcatttgt tgctatccct ttgcctcaat agttcctagc
     2941 aagccagtaa cctaattcag catttttatt aatagaggta tcttcttcaa atgttaggct
     3001 gatacttcca atagcccttt cttgataaaa aatagcatag ctaagttgtt taacatctga
     3061 agttgccaaa caaaaactaa caaaatctct agcgttttgc tccctataag ggtgggggaa
     3121 gttgtcacga agattctttg caatttcttt atcattcgca aactcaacta aatcggtaat
     3181 ataagcataa ttccactcta taagttccat ttttcttctc cttttatgaa acagctacaa
     3241 gaaatctttc taagccaata ccacttatca aacagcgttc tcttttattt ccaagcattt
     3301 gataagtcca gtcaacaaat ccaccgtcaa ctatttcaac ggtttcattt ccttgtttga
     3361 ccgataattt gaaattgata cctttataat aattattatc aacatcatca ttatgaattg
     3421 ataactctat attaggaaaa ataagtttga tagtttcaac cattctgtcg aaaaatccgt
     3481 cattatcttt gtatccgttt cttttgcgta gaataataga gaaacgaaca ttttctattt
     3541 cacttaatat atctttataa tagtttaagt gcttttctaa caacattttt tcacaagtgt
     3601 aagaccctgt atctatacca gatgaaacca tacaatataa gccaaaatgt gaatataaac
     3661 ctttacctac aaaattttgt gctcttatta ccctagcagt agtagccatg tggataggta
     3721 tggtattatt ttcttctttt ctttttaatt tatcagcaat aattattgcc aacatatttg
     3781 aggggtctgc aagtgtttct gtccctcgta gagcacttac tacgttatat tgatctacgg
     3841 agccaaaaac gctacagcta cctaatgggg cagagggaga aagcataatc gtcttgatat
     3901 ccatattgaa tgcttttctc aataattttg attccaaagc atgaatttct tctggatcta
     3961 taccgctagg gatagtaaat ctatttagtt ggtatgactt tagaatatca gttgcagtta
     4021 aagtatttgc ttgtctatca aacacttcta atagaagtga gttcaaatct gattttgata
     4081 gagctgataa cttatcaact atattcttat ccccaatttt atttgtaatt ctacttaaaa
     4141 tatcactcat agttatcctc catactgtta ctttcaaaat aattatagaa ttgttacaac
     4201 aactaatcta ggtcatttga ccaaaaatga aaaaacactg aatatttact attcaatatt
     4261 tttttacttt gggtttattt gattaaatct tgaaaatact gtaatgcaac cctttcagct
     4321 tcaacctttc ggacaatagg actttgtgat aattcctctc ttaactcaag atacaggttg
     4381 atagtagcct gcaatgcatt aacacagctt ttatattcat ggttagcaac cgtcttttct
     4441 aatgcttcaa tatattgggg tgcgtccaat tcaatttttc taactccacg aggtaattta
     4501 cctaagagaa gctgtattaa tggggcaagt actgattgtc ttaaaaaaga taaaaaatca
     4561 attgtttcaa atagttctct acgtccaatc ttagtgcaag cgtaatgaac ccaaatccaa
     4621 aatctatctt caatccactg taagtctgga gttgggaagt atgcttcttt tttagaataa
     4681 atttctgtta tgcagttgtt ttcttcatag agaatagctg aatcttcaac cctatctagt
     4741 aaaccatcta aggttgtaaa cttaaaatca acatgaagaa caggggaatc atagagggaa
     4801 attatcaatc gaggttctcc aacgtgttcg ccagtaaaag cagaaactaa tgttccaaac
     4861 tgttccacaa taagtaatct ctcttcgata acttcttcat aggatttatc atctgctaca
     4921 atcagaaaat ccaaatcaga atattcatct aacgattttg tgatataaga actgctaatt
     4981 gcaagtccta ttatcctact atctcttttt gaaaattcta atacgttttg tatcattttc
     5041 tgttgtgttt tagtcataat ataacacctc tcactgtctt ttattagcta tcaatccaac
     5101 ataattatgc ataggagtat tatataatga agaaataaaa aaaaataggt cacttgaccc
     5161 gaaataaaaa agcattgaat aattattatt caatactttt ttgaaattat acttatgttg
     5221 taggaagatt ctttaatacc tctcgctgat taattacact aaatcttttg ttttcataag
     5281 caattagatg ttcttgtaca cattcattta tagcacgatt aatgcttcta attggagcgt
     5341 ttacttcgct agcaagctgt tttttggtaa gcagatttaa ttcacttcta taatagtgta
     5401 aggatataca cctcagaagt cgttctttaa cacttaaaga tgataattct tcaattaatt
     5461 cagcatttac aactaattta ctagatattt ctcgaatcag aaattttgta gcttcaaaat
     5521 ctccccttaa ccagtttaaa aaatcatctc tatgaagttt atatacatta caatctgtga
     5581 aagcgacaat ttcaacgggt tttttcccat cattaaattg ttccatttct ccaaaaaaac
     5641 taccacttct ataaagatga atcgttgaga tgtttccttt cacatttaag atgaatgctt
     5701 ctgcaatacc gtcaatcata agaattacat attcattttc ttgctcagca aaaagaatag
     5761 tctctttctt tttatacgtt tttttaacaa gcttcttttt aatatcttca ttcataaaat
     5821 caattaaatg catattcatc cctccttacc aaatctttga ttaaattata tcatctttca
     5881 attagttagg taagatagta aaaatatatt tacatagaaa ctattccatt attattttcc
     5941 agttgtcatt tttctgcaaa aacttatcac tgtcacgact ggagatacca gtaaggaatg
     6001 ttaggatatc aatcgctaaa ctttcagaat cctttttacg gctcaaaatg acgtaagggt
     6061 caagcaatcc tttgttttca tcattactgg ttaaattgac aatgtttatc tcatgggcta
     6121 tttctggtag cgtttctttc catttgccgc gttctgcttt agggtcaact atgaccgcct
     6181 gtccgccgaa tagtaccgca tagtaaacaa gcatattgtt actgaataat ttaccaccac
     6241 ccaatgaacc gataaacgca gacgctaacg cattggtaat agaacccttt accccttgac
     6301 tagcaagggc aggttttaga tagacattct ttccagtgtc cagattgtag ccaagataga
     6361 tatcctcatg ttcgccaagg gtttgtgtcg ctccaaaacc aagtccagcc aaaaaatccg
     6421 aagtgacata ttgaatataa tcattgatgt aacgtttgct gacaggaata aattcgccat
     6481 gcaatcccaa catatcccca aagggacgca cgagcttgat tgataagtcg tcgtaaaagt
     6541 ctttgacttc atcacaacgc ctttttagct cgtcaagatt ctttgtagat acacggacaa
     6601 catagctaag tttatacata gattctttac agttaaaagt ctgtttttaa aaaaatgtat
     6661 aaattataaa tcaaaatata gatactatca atgacccact aggtgcaaaa agcattgata
     6721 tggttaaatt atcagacgct aaaagctggg ctatccgaat gagtgaagat gggtgtgctt
     6781 ataaatccat tgacaattat aagcgctcac tgaaagcgtc gtttttcatg gcaattcaag
     6841 acgactgtat tagaaagaat ccatttaatt tttagttaag tgatgttttg gaagatacaa
     6901 cagaaccaaa aatcgctcta acaccagaac aggaaatggg cttattatcc tttatgggga
     6961 gcgataagac ttattgtaaa tattatgatg atgttgttat cctcttagaa acaggactac
     7021 gcatttctga attatgcggt ttgactttag aattggatat gaaaaataaa gccattatgg
     7081 tagaccatca attgttgagt gatactaaga ttggctatta tgtagaagtt ccaaagacca
     7141 cacagggtaa gcgagaaatt ccaatgactg aaagagctta tcaatcattt gaacgtatcg
     7201 tggaacggcg taagaacgct aaagcagaac caatcattgt tgatggttac cagaacttcc
     7261 tatttcttaa acaagatgga ttaccaaaac aagcaactca ttatcaaagc atgttaagag
     7321 cgttagtcaa gaagtataat aagacccatg aggacaagct accaaagatt acgccacata
     7381 cctttaggca tacactctgt acaaatatgg ctaacaaagg aatgagtcct aatatattgc
     7441 aatatattat ggggcataaa aacattacta tgacgcttgg ctattatgca catggttcat
     7501 ttagttcttc gagagctgaa atggaacggt tataatccta gtagtatgac tagagtttac
     7561 tacttattta ctacttttga tggcattctt atacggttaa atgccaactt atgcaaagta
     7621 tcttccaaaa agaaaatgcc gatactcctt gtagatacag gatatatcga catttaccaa
     7681 cttatgaaaa gataatcaaa tttaatataa gtttttcaaa taaaaagata ccaaattctt
     7741 tttcgagaat ctatataaca ttacttaagc ttggttgggg tataaacaat tgagtagcta
     7801 cttttgtatg gtgttcaact ttagtcaaaa ctcttaagta atgcaaatga tttagattca
     7861 ttaatattca atctcttcat aagtagtgaa attcgagtta tttctgcata attatactat
     7921 gatttataga ttaattctat tagcatccag aataatattg tttatatgag taaaatttaa
     7981 agaatattgt gaaaattata ggatgttaaa ataaatttag gtaaaaaaga agtgtttgta
     8041 tattatagag taccttttct aaaatatgtg ggattgtttt aagaattaga ataaaaatta
     8101 tttttaaatt agtattttta taatgtatag tatttttaat gtataattaa attgtgcaga
     8161 aaatagaatt taaagtccta tagaatttct gattatggag gagaatatga aaagaaaagt
     8221 tcaagtaaaa aatattacta ttggagaagg tagacctaaa atttgtgtac caattattgg
     8281 gaaaaataaa aaagatatta taaaagaggc taaagagtta aaagatgcat gtttggatat
     8341 tatagagtgg cgagttgatt tttttgagaa tgtagaaaat attaaagaag ttaaggaagt
     8401 tctctatgaa ttaagaagtt atatacatga tatcccttta ttattcacat ttagaagtgt
     8461 agtagaaggg ggagaaaaat taatatcaag agattattat actactttga ataaagaaat
     8521 ttctaataca ggtttagtag atttaataga tgtagagtta tttatgggag atgaggtcat
     8581 agatgaagta gttaattttg ctcataaaaa agaagtgaaa gtaattatat ctaatcatga
     8641 ttttaataaa actccaaaaa aagaagagat tgtatctcgt ttatgtagaa tgcaggaatt
     8701 gggcgcagat ttacccaaaa tagctgttat gccgcaaaat gaaaaagatg tgttagtgct
     8761 acttgaagct acaaatgaaa tgtttaaaat ttatgcagat agaccaataa taacaatgtc
     8821 aatgtcagga atgggtgtta taagtagatt gtgtggtgaa atatttggtt ctgcattgac
     8881 ttttggagct gcaaaaagtg tttcagcacc agggcaaata tcatttaaag agttaaattc
     8941 agtacttaat ctattacata agagtattaa ttaaattaat tatatagaaa tattagacgg
     9001 tatttttgaa gatataaatt aaatataaaa aacttttcag atagtaaaat ttaaattggg
     9061 caattatatc tgaaaagcaa ctatttagtg tgtattttga aagtgatata gaaaatctta
     9121 taaatcaact atggcatatt taaaatatgc cattaaaacc tactagacat tagattatag
     9181 atggtatact agcatttcta ttatttatag atagtaagtt ttcataataa ctgttttatc
     9241 taaagtagaa gatatatttg tattatgtat atttgtcatt atttttttgt aattatgtat
     9301 attaatggtt atatatgtaa tataatatta tcactctatt ttttgtatat tgtacattac
     9361 aacatttata tctatcatca tcaattacag tagaatgtat gggatactta ttttcactta
     9421 accaatattt ttgcatattc tttgtccaag actttggaaa cttcaatact ttcttgttta
     9481 ttataacatc ctcatcttca aaaatattaa cttctctttc tatttttatt tttctgttgt
     9541 atatcttatt gatagattct ttgtcgagtt ttatgtctct atacatatca gggcaatagc
     9601 aacaaacata atttcttttt tttcgacgtt taaatttcac aactttctct atgctaattt
     9661 ctaatttttt tgtaccatct tttataaatt taatatcttc tatgttctcg cttgaaaaaa
     9721 tttctgtcaa tcttaaagta tctacagttt ctctaattat ttgcttttta taagaagaga
     9781 atccatatcc aaaagaaagg tttaatttat tagggatgta gccattttta tatttaaaca
     9841 tcttaatttt ttccaattca gcattatctt taaatttcaa cttttcatac ctaaaagtta
     9901 ctttgctaaa aagagtatat tctacatcaa tatattcttt tgcaatctta aatttatcgc
     9961 taccttcaat cacaatcata gcctatctcc aatcgtttta tattaaaata aggccataga
    10021 acatggtcta atagtactca ttagcactat aagacaatgt taacacaaaa agacaaaaaa
    10081 aggttattta tttcaaataa cctttttttt tatataaaat ataaagaatt atattttatt
    10141 cttttttatg atgtctataa tctgtgatat cagatttagt tctcttgaat ttaagtcttt
    10201 taactcttca tttatatcat tttctaaata tgtttttcca gtggaagtaa tatcttttat
    10261 aagaacatct gcagaaatat ttaatatatt tacaaatttt atgaatgttt taagacttgg
    10321 attcttttta ccactttcga tttgagttat ataccaaggc gatactccaa ccatatttgc
    10381 aaattctttt gaagttaaat ttgctttttt ccgttcttct ttaagtcttt tacctatata
    10441 attcattatt gttactattt ccctcactta tatttctttg tatttaatga tgcactttat
    10501 taactctagc attgcaattt gttctttttc agttaattta ttaatcattt cataacattc
    10561 taaaggtaca gagttatcaa cgccttctgt tgtaataata tttgcaaata acaattcaag
    10621 tggtatgtct aaagcagtag caattttcat tataatattg atagatgtat ttgtctcagc
    10681 tctttcaatc tgaccaatat atgttggatg taaacctgcc ttttctgcta gaaactcttg
    10741 actatatccc aattttgttc tatagacttt tattctatct cctattattt ttcctatatt
    10801 tgccaattat tatccctcca ctttagatta tattcatagt ttaagttgtt ttatatagac
    10861 tatttatact tttttagtct aaatatagac tatatatgtt tttatactga aataagtgct
    10921 atttattttt gtatagtctg tatctacaat aaacaaatat ggataaatca tatttttaat
    10981 tagagaaata ttttcataat ttcatagcca tactacaata ataaaacgaa tta
//
LOCUS       DAMJWC010000101        10930 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMJWC010000101 DAMJWC010000000
VERSION     DAMJWC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.106"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            79..1575
                     /locus_tag="PC503_003331"
     CDS             79..1575
                     /locus_tag="PC503_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2529286.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            1709..2635
                     /locus_tag="PC503_003332"
     CDS             1709..2635
                     /locus_tag="PC503_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2529287.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            2753..2944
                     /locus_tag="PC503_003333"
     CDS             2753..2944
                     /locus_tag="PC503_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529288.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            3167..3517
                     /locus_tag="PC503_003334"
     CDS             3167..3517
                     /locus_tag="PC503_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529289.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            3778..5283
                     /locus_tag="PC503_003335"
     CDS             3778..5283
                     /locus_tag="PC503_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF2529290.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            5673..6770
                     /gene="dinB"
                     /locus_tag="PC503_003336"
     CDS             5673..6770
                     /gene="dinB"
                     /locus_tag="PC503_003336"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF2529291.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            7033..8169
                     /locus_tag="PC503_003337"
     CDS             7033..8169
                     /locus_tag="PC503_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529292.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            8162..9709
                     /locus_tag="PC503_003338"
     CDS             8162..9709
                     /locus_tag="PC503_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2529293.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            10044..10910
                     /locus_tag="PC503_003339"
     CDS             10044..10910
                     /locus_tag="PC503_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2529294.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         4228 a         1149 c         1979 g         3574 t
ORIGIN      
        1 atagaaataa ataaaaaata caatatacat aatagtagaa atatagcaaa aaggtgtgat
       61 ttatagggag gattacttat gtttgaattt gaaacgcaac taaaaaggtt aaaacatgaa
      121 gttttaacag cagtagcaag actatctatt gaagaaaatt taacaaaaga aaatatagaa
      181 aaaattccat atgaaataat taaaggagaa aaggcgagat atagatgttg tgtttataaa
      241 gagagagaag tagttcttga aagggcgcaa cttgcattaa gtttaactcc aaatagtaaa
      301 tatggagata taaatccaga ttcagttagt ttggacacag atgagcaaat tatatatata
      361 gttgaagcag catgtgatag atgtccaata aatgaattta cagttacaga gctttgtaga
      421 gggtgtttgg ctcatagatg taaggaagca tgtaaatttg gggcaatttc ttatataaat
      481 gggagagcat atataaatca tgatttatgt aaggcttgtg gaatgtgcaa aagttcatgt
      541 caatatgatg ctatatcaga agttgtaaga ccttgtaaaa gcgtttgtcc aacaggagct
      601 ttggatttta atagaaacac tatgaaagca atgatacatg aagataattg tataaattgt
      661 ggagcatgta tgtcagcatg tccttttgga gcaatatctg ataagagttt gatagcacct
      721 gttgcaaaaa aacttgcaaa gaaagaaaat atgtatgcaa tagtagctcc agctataaca
      781 ggtcaaatag atagtaatat tacatatggt cagttaaaaa atgctataaa atcactggga
      841 tttgtagata tgatagaagc ttcttgtgga gcagatgcag ttacagttca tgaaagcaat
      901 gaacttattg aaagaataaa atcaggagat aattacatga caaattcatg ttgtccggga
      961 ttttttaagt atatagagaa gatgttccca gatgaaaaag atagaatatc atctacagtg
     1021 tctcctatgg tagcaacagg aagattagta aaaaaaatag attctgatgc taaagttgta
     1081 tttataggtc catgtacagc taaaaagagt gaggcaacag agaaaagttt aaaagattca
     1141 gtagattatg tacttacttt tgaagaacta atggcattat ttgaagcatt taatatagat
     1201 ttatcaaaat gttcaaatga agatataaat gatggttcga tttttggaag gggatttgga
     1261 gcatctggtg gacttgccaa atcagtacag aactatattg ctgaaaaggg gcttagtttt
     1321 gattttgaac ctataaaagt atctggtcca agacaaatta aaaagacaat gacaatggct
     1381 aaattgggaa gattagaagg taattttata gaaggaatga tgtgtgaaga aggttgtatt
     1441 aatggagccg gtaagttttt atcaggtgta aaagccaaaa atacttttga tagaaaaaat
     1501 ggacaatcta ctaaaaagag tgttttatct aatgataaga ttaaagaatt tgaagatgta
     1561 aatttagaaa gataattgtt ttggtacagt cattttttta ttatgccaca aatatgccta
     1621 aaatttgccc tttttatatg tgtattttac agagttaagg ttgctatact ataaatatgt
     1681 aataaataaa atttatagga gcttttggat gaggaaaata gtattaaaag atatcctgtt
     1741 tttagttact acattatcta taatagtaat attattgctt gtaacaaata taactactaa
     1801 tagtaagata aaatcaacaa gtgaatctta tttaaaaagt gacaaaaata gtgtgaggca
     1861 aaatggtatc cagaggagca caaagagtag cacaaaaaat actgcattta agactactat
     1921 actaaacact ggaaagtctg attgcatatt ggttgagata ggtaacaaag tcataatgat
     1981 tgatacagga gaagataaaa atggaaaaca aatagtggat aggttaaaag aaaaaggaat
     2041 aaatacactt gactatttga ttttaactca tttagataag gaccatatag gtggagtaga
     2101 tagtgtgtta tctagtgtta aagtaaagaa tattatacaa gcaaattata agaaagatag
     2161 taagcaatat gatgaatata ttgactcact taaaaaagct gatatagaac cagtgctact
     2221 aaaagataat atgaatattg taatcaatgg tgcagaaata aacatacatc cggcttcaaa
     2281 aagcaagtac gagagttcaa atgattattc aataatcact aatataagct atggagcaca
     2341 taagttttta tttgcaggag atgcagagga agaaagattg tcagagttta taaatggaaa
     2401 tactttaaaa tatgattttg ttaaaatgcc tcatcatgga agatatgaca aattaactga
     2461 aacattttta gagtctattt cacctcaata tgctgttatt acatgttcag agaaaaaaga
     2521 accagaggaa ggtgttttaa aaatattgga aagattgaat ataaaaacat ttttgacttc
     2581 taatggagag gtagttatca atagtgatgg taagacattg agtgtgaatc aataattttt
     2641 ttaaaaatat ctaaaaaaat ttaaaaaaat cattagcaaa tattacccct taaacatagt
     2701 atattttagg agctgaaact ccacatacaa aatgactagg aggtaacata ttatgttgga
     2761 tagatttttt ggtgaaggcg gatttggtgg atgtgcttgg tggataataa tattattctt
     2821 cttattctta gcattccaag attgttgggc tgaaatggac ttatgtgcat ggataccttt
     2881 cttaatatta ttattaatac tttgtgaatg tggtgacgtt tttgatggag gatgtggatg
     2941 ctaaaaaaat caatttagat gatttaataa agcttatggt gggtataaat aaaataccaa
     3001 accaatcaca atctagtgtt tgaaggtagt cggaaatccc ccgctacctt ctttttttta
     3061 ttgttaaaat ttatttttga attatttcat ttacatataa taatttttac gataaagtct
     3121 gatataatta aaaagaaaat aaaatttatt tataggagat gtaaaaatgg ctatagtgga
     3181 taagattttc aatgagataa aacttatggt tgcaagactt ttattgggaa aaaaatacag
     3241 tgaatatgaa gaaaaagatt tagtgtataa tacagaagaa gaagttatac ttataacttt
     3301 aaaaagatta gtttttcagg gaaatgtaaa cgaagcagaa gaaattttat ttgataaagc
     3361 taagagtgta aatagtgaaa atatgcagta tatagcaata gaattttata ctatgcttat
     3421 ggaaaagact gatgaagaat tagaagctat gaatttttct aaacaagaag tttatcaagg
     3481 tatagaagat attagaaaag tattgaattt agaataaaag atatatgaaa atattgaaat
     3541 aaattaatgc taaggtgaga atattatact tatatataaa aatatagtat tcttatttta
     3601 ttagttatat aggtatatct tatttaccat aaaactatct tgaaaaaaat taatcttaat
     3661 tgtataatat tactttgagt gaaaaagtat taacattttt ttataagatg ttttactaaa
     3721 aaaatatata taaatatact gttatcaaca agaaatttaa tttagtgagg tgttaagatg
     3781 aaagtaggat ttgaccacaa aaaatattta gaagagcagt ctaaatatat cttagaaaga
     3841 gtaaataatt ttgacaaact ttatttagag tttggaggaa aattgatggg agaccttcat
     3901 gcaaaaagag tacttccagg atttgatgaa aatgcaaaga taaaagtatt acaacatatg
     3961 aaagaaaaag ttgaagttgt aatttgtgtc tatgcaggag atatagaaag aaacaaaata
     4021 agaggagact ttggtatcac ttatgatatg gaagttttaa gattaataga tgatttaaga
     4081 ggttatgaac tagatgtaaa tagtgtagta attactagat ttgaaggaca acctgctaca
     4141 actgtattta taaataaatt agaacgtaga ggaattaaag tttataagca ttatccaaca
     4201 aagggatatc cgtcagatgt tgagactata gttagtgatg agggatatgg agcaaatgaa
     4261 tatatagaaa ctacaaagcc aatagtagta gtcacagcac caggacctaa tagtggaaaa
     4321 cttggtactt gtctaagtca gttgtatcat gaaaataaaa gaggtaatgt agttggatat
     4381 tctaagtttg agacattccc agtttggaat gtacctgtaa aacatccttt gaatatagct
     4441 tatgaagcag ctacagttga tttaaaagat gtgaatatga tagattcatt ccaccttgaa
     4501 acgtatggtg aaatgtcagt aaactacaat agagatttgg aattatttcc agtgcttaaa
     4561 aaaataatag aaaagataac tggaaaagaa tcaattttcc aatctccaac tgatatgggt
     4621 gttaatagag ttggctttgg aataatagat gatgaagtaa taagaaaagc ttctatagaa
     4681 gaaataataa gaagatactt taaaactgcc tgtgagtata aaaagggaca agttgataaa
     4741 ggtgcttatg atagaatgaa aatgattatg gaagagctta acttaaagcc agaagataga
     4801 aatgttgtat tacctgctag aaactacagt aataaattga aagaaagtgc cgacaagaat
     4861 gatacttgtc ctgtagttgc attagaatta gaagatggta caatattaac tggtaagggt
     4921 tctgatttaa tgaatggaac tgcagcagta gtattaaatg ccattaaaca tttagccaat
     4981 atatctgatg atatgcactt aatatcacct gtaatattag aacctatcat aaacttaaaa
     5041 acaaagactt tagctagtag aaatgtttca cttagttgcc aagaggtgtt aactgcactt
     5101 agtatttgtg ctgtaactaa tccaactgca caatttgcta tggaaaagtt agcattatta
     5161 aaagggtgtc aagctcattc tactactata ttaaatagag atgatgaaca aacatttaga
     5221 aaacttggta tagatgtaac ttgtgaccca gaatatcctt cacaaaatct ttactatagt
     5281 taaaattata taaaaaaata tgggctgttt taaagtaata gtttgagcag tccattacaa
     5341 ttataataaa atcagtaggc tgtcttgtat aagacagtct tttgttttta aaacatccca
     5401 taaattaaat atatatactg ttatccataa ggaattttaa atttagttcc ttggaatacc
     5461 tattgtaaag cttttatata gtttttgcaa gtgtttttaa ggatttttta taaattatat
     5521 tgaagttaat ggattataga tggttttatt tatggaaaat atgaatatat aaagaaaata
     5581 atgaaaaaat accaaaaaga aacataagtt tggtataatt aaaaagtaat ataaataaaa
     5641 ttaatctatt tatactttaa aaggtgataa taatgaaaca ttatagaaaa ataattcata
     5701 tagatatgga cgctttttat gcatctatag aacaaagaga taataaaaaa ttaaaaggaa
     5761 gacctgttat tgtcggtgga aatccacaaa gccgaggtgt ggttgcaacc tgttcttatg
     5821 aagctagaaa atttggtatc cattcagcta tgccatcagc tgtagcttac aataggtgtc
     5881 catatgcagt ttttgtaaga cctagatttg atgtttataa gagtgtgtca gagcaaataa
     5941 gagatatatt ttatagatac acagatttag ttgaaccatt atctttagat gaagcttact
     6001 tagatgtaac aaaaaataaa aaaaatattg attcatcaat tgagatagca aagcaaataa
     6061 aaaaagatat atttagagaa gttggtctta cttcttcagc tggtgtgtca tacaataagt
     6121 ttcttgctaa gattgcatca gacttaagaa agccaaatgg gttaactgta ataaccgaag
     6181 aaaatgccca ggacttttta gataaattac ctgtgaataa attttttggt gttggaaaag
     6241 ttacttcaaa tactcttaaa aatttaggta taaaaactgg atatgattta aggtgtttaa
     6301 atttatttga acttgaaaat atattcaaaa aaagaggtta tgaattatat aaatttgcta
     6361 gaggaataga cgatagacca gtggaaccaa atagggttag aaaatctgtt ggggctgaga
     6421 ctacattaag tcataatttg gatattgatg aagaagaaac acgcaacatt cttgatgaac
     6481 tttgtgaaga agtatgtcat agattaaaaa actctgagaa gtttggaaaa acattaacat
     6541 taaaaattaa atatgaggac tttacaaaga taactagaag ccttagttta gaacactata
     6601 ttgacgaata taatgatata agaagtggtg tagataattt gttgagaaat gttgaggtta
     6661 atggaaaaca aattaggcta ttgggagtta caatatcaaa cctaagtgat aaaaaagaaa
     6721 cttataaaga tattacatta tttgaataca tggatagtat ccaaatgtga gttttgttta
     6781 aatgaaataa cactagcttt aatactatat aattgaggct agtgttattt tatgaatatt
     6841 tttatatttt ttgttttttg acattgtata ttatatacta tatataaata ctttatattt
     6901 gtagcaatat tcagacaaat agtgacctaa aaatcgtact ttgtttacat aaataaaata
     6961 gtatgatata attataaaaa caacttataa tattggagaa ggttgcttgt tcgaaaaagg
     7021 ggatgataaa ttatgataga gataagaaat gtaacaaaaa aaataggaaa taatgttata
     7081 ttagatgata tttctctagt tgtagaaaca ggtacattgg tagttttgat tggttcaagt
     7141 ggttgtggaa agactactac tttgaagctt ataaacaaat taataaaacc tacatctggt
     7201 gagatatata ttaatggcaa accaatttct caggaaaatg aaatagagct tagaagaaaa
     7261 ataggatatg ttatacagaa cacaggccta ttccctcatc ttacaataaa agaaaatata
     7321 gagctaattc cacgcctaaa aaaggaaaaa tccgttgaag aaattgaaaa aagaacgttg
     7381 caactacttg agatggtagg acttgatagt gatgaatttt tgaataagta tccttcagaa
     7441 cttagtggtg gacagcaaca aagaatcggt gttgcaagag ccattgctac tgatgctgaa
     7501 ataatattga tggatgagcc ttttagtgct ttagacccaa taacgagaac atctttacaa
     7561 gaacaattat tttctcttca agatgaattg aaaaaaacta taatatttgt aacgcatgat
     7621 atggatgagg ctttaaagat agctgataaa atttgtatta tgaaggatgg aagaatagca
     7681 caatatgata ctcccgaaaa tatacttaga aagcctgcaa atgactttgt aaaagatttt
     7741 atcggagaag atagagtttg ggataatcca gaatatataa aagcaagaga tattatgata
     7801 aaaaatccta ttgctgttaa ttctactaga actgtaactc aaggaataga aattatgaga
     7861 acgagtaagg ttgatagctt actaattata gatagagcaa aaacattaaa aggtattgtt
     7921 actgtaaaag atatgaaaga tattgatgat aagtcaatat tacttgctga tattatgtca
     7981 agtgagcctt tgcatgtaaa tgaaggggat aatttagtag aaatactaaa tgtaatgaat
     8041 cgtaattcgg ttggatatat tccggttatt tctgatgaaa ataaactggt agggcttatt
     8101 actagaagta gtttactttc tgttttaagt gaacaattct tagaaatgga ggtgagtgtt
     8161 cttggctaat ttttttaact ttatactatt acaaaaagat aagattatag agcttttaat
     8221 acaacatatg agtctaactg ttacatctat tttaatagct ataatagttg gtgttcctct
     8281 tggaataatt atttcaagaa tctcatctct tagaaagttt gtacttggat ttgtaaactt
     8341 agtccaagca gttccgtcta tggcactttt gggtcttctt gtacctatac ttggtatagg
     8401 aagtaaacca gccatattta tggtagtggt ttattcatta ctaccaattg taaaaaatac
     8461 gtatataggt ataacaagta ttgacccagt agtattagaa tcagctaaag gtattggtct
     8521 tacaagaaat cagacattat ttaaaataca attcccttta gcacttccta taataatggg
     8581 tggagttaga atatctgcag ttacagctgt tggtttgatg actcttgcag catttatagg
     8641 tgctggtggt ttaggatatt tagtattttc aggggttcaa actgtaaata ataatatgat
     8701 tttagcaggg gcaatcccat catgtataat tgcactgtta gttgattatt tatttagtaa
     8761 aattgaagtt gcagttactc caaaaggatt aaatccaaaa gcacctaaga agaattatat
     8821 agcacttaaa gtaatatctg tagtggttgt tgtttcaatg ttgttcgttg tttttagttc
     8881 tagtttttca agtaaaaaag atacaataac tattggttct aaagattata cagaacaact
     8941 tatacttggt aatgtttatg ctgaattagt agaaaaaaat acgaatctta aagttaagaa
     9001 gaatttaaat ctaggtggtt catctgttgc gtttaatgca attaaatctg gtgagttaga
     9061 catgtatgtt gactatacag gtacactttt ggtaaatgta atgaaacatg ctccgattaa
     9121 agatgctgat gaagcatata atgttgtaaa agatactatg gaaaaagaaa atcagttaac
     9181 tttacttgac cctcttggat ttaataatac ttacacatta gctatgatgc ctgaaactgc
     9241 tgaaaagtat ggaataaata ctatttctga tttgactaaa tatggtaaag aatttacatt
     9301 ctcaccaact ttggagtttg aaaatagaga agatggtctt gtagggcttt ctagagatta
     9361 tggtttaaaa ttcaaagatg taaaagcaat gaatggaagt ttaagatata cagctttaga
     9421 taataatgaa tctcaggtta tagatgcatt tttaactgat ggtcttatta aaaagtttaa
     9481 tcttaagata ttagaggacg ataaaaattt ctttgtacca tattatgcag caccattagt
     9541 aagagaagat actttgaaga aatatcctga gttagaaaaa gttatgaata tgctttcagg
     9601 aaaaataaat gaagaaacta tgagagaact taactatcaa gtggatgaac ttggtaaatc
     9661 accagaagaa gttgctcatt cattcttagt taaagaaggc ttagtataaa aaattaatag
     9721 tttatatcaa aaaatttaag agagtgtctc aaaatgaact ttttagttca tgaggcactc
     9781 ttttttatat gaaatcaaat atattttatc atttcaacaa taaaaaagaa gattatcttt
     9841 attttgagac agtctcttat ttttatgtat accaaaacca tacctacgat ttttatttat
     9901 aattaagttt caaatagaat gaacaagtac aaccaatttt gaatataaat atagtaaatg
     9961 tgcttatata cgattttatt gtctggttga ttgatattga tagatagctt tctttattga
    10021 atcgaaggga gggggaattt gttatggata actataagaa agtgaagcaa gtattgtgga
    10081 taattttatt tgctaatttt gcagtagcat tattaaaaat cattattggt aatcaaataa
    10141 aaagctatag tatgacagca gacggatttc attctttgtc agatggagca tctaatatag
    10201 tggggcttat aggtattttc tttgcatcta aaccaaaaga taaaaatcat ccttatggac
    10261 ataaaaagtt tgaaattata accagtttat ttataagtgg tatgttgttt gttatagcaa
    10321 ttaagataat tcttagtgca gtgttaagaa tagctaatcc agttgtacct gctataacta
    10381 tagaaagttt aattgcttta attattacac tttttataaa tatttttgta tgcatgtatg
    10441 aatatagaat tgggactaaa ctaaatagtt atgttttgat ttcggattca ttgcatacaa
    10501 gaagtgatat atttgtgtct ctaggtgtat tggttacttt agttggtgtt aagttaggat
    10561 ttccagtaat aatagaatct atagttccta ttattatttc tgcattcata atttattcgg
    10621 cttatggaat atttaggcca tctattggaa ttttggtcga tagagtggct gtagatgagg
    10681 attatataaa agaaattgtg tttgaattta atgaggtaag ggatgttcac aatatcagaa
    10741 gtagaggtag caaaagttct atttatattg acatgcatgt aatggtagac ccatttataa
    10801 gcgtagagca atctcatgat ttaacacata aaattgagaa acaaatacaa gaagaaatta
    10861 atgaaaatgc tcaagtaata gtccatattg aaccttttta tagtttttaa cttagctata
    10921 aaatacaagt
//
LOCUS       DAMJWC010000102        10808 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMJWC010000102 DAMJWC010000000
VERSION     DAMJWC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10808
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.107"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            194..1354
                     /locus_tag="PC503_003340"
     CDS             194..1354
                     /locus_tag="PC503_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2529295.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1696..1857
                     /locus_tag="PC503_003341"
     CDS             1696..1857
                     /locus_tag="PC503_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529296.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2050..2679
                     /locus_tag="PC503_003342"
     CDS             2050..2679
                     /locus_tag="PC503_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF2529297.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2918..4177
                     /locus_tag="PC503_003343"
     CDS             2918..4177
                     /locus_tag="PC503_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2529298.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4436..5431
                     /locus_tag="PC503_003344"
     CDS             4436..5431
                     /locus_tag="PC503_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF2529299.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5677..6744
                     /locus_tag="PC503_003345"
     CDS             5677..6744
                     /locus_tag="PC503_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF2529300.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFAEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7278..9188
                     /locus_tag="PC503_003346"
     CDS             7278..9188
                     /locus_tag="PC503_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2529301.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9251..9874)
                     /gene="ytaF"
                     /locus_tag="PC503_003347"
     CDS             complement(9251..9874)
                     /gene="ytaF"
                     /locus_tag="PC503_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF2529302.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10062..10706
                     /locus_tag="PC503_003348"
     CDS             10062..10706
                     /locus_tag="PC503_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529303.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4429 a         1063 c         1764 g         3552 t
ORIGIN      
        1 aattcagatt attcatttct aaagtaatta atgtgcaaat ctttattaat atatgtcaat
       61 agttaggtat atatgtattt aattagcatg atatagataa aagtatttat tttaattgtc
      121 tattatctga aaaagtcttt acttagaaat cataaaaatc aaattaatta ggaaaagaaa
      181 gggtgtgtat aatgtgattg agactggatt tgtatattgt agtttcttgg ttgtattcgt
      241 aggtgtaatt ttttttatgg ttgataaatt gaaatggaag gtatttgatg ttattaatcc
      301 aatgctttta atatacttag gttcagctat acttggatca tttggtttat ttgcacagaa
      361 tgaagatgtt ggaacgtatc aaaacataat aacagtgaac ttccttccat taatgttagt
      421 gtttttgtta attcaatgtg atttaagaaa aatattaaag atggggccta aaatgttatt
      481 atcatttttc tgtgctacat ttacatttat gcttggattt gttatagcat tcataatttt
      541 taaaaattca atgggtgcag attcatggaa aattcttggg gcagcatctg gttcatggat
      601 aggtggctca tcaaatatga ttgcagcagc taatgctcta ggagttgcag aagaaggact
      661 tagttatgca atacttatgg gttctatagg atatacagta tggatgtctg tttgtctaat
      721 gtctgtgaaa tttggaccta aatttaacaa atggacaaag tgcgatacaa gttttataga
      781 tgaggttaca tcaaaacttg aaaaagaaaa taaagataat acagcaccta cgtttgtaga
      841 acttatgatt ttactttctg ttgggtttgg agttgcgtct tttgcacaaa ttgtatccaa
      901 gatacttcca acttcaggta tacttaatga aactatgtgg gtagtacttg ttgcatctac
      961 agtatcaata ttattgggta tgacaaaaat atcaaagctt aaagggagta cactggtagg
     1021 aaatgtgttt atgtatttac tccttgcagc tacaggtagt aaagcaaatt tctttggatt
     1081 gtcagaagca cctgtttaca taatgtttgg attggtagta gtccttgtac atgctatttc
     1141 atttataggg cttgctaaac tatttaaact tgatttattt acttgtgaag taggaagtat
     1201 agctaatata ggaggagtaa ctacagctcc aatgattgct ggggttcaca atcctgtatt
     1261 aataccagta ggtgtactta tggggcttct aggaaatatt atagggactt attgtgctct
     1321 tatggtaact caaatattac atatgttagc ttaataaaaa tatggtataa aattaataat
     1381 ttaaataaga aaagtcattt caatttaagc agaagctttt actgaaatgg cttttttgtt
     1441 tgacaagata atctatttca agaagatgtt ttgacatatt tagtgtataa tattgtaaaa
     1501 tttactaaaa acgagatata tttaattttt atattgaatc gaacgtctgt atgatgtata
     1561 ataaatatac agaacgaatg tttgcagaac gggtgttttt tgaatttatt ttaataattt
     1621 atgaatatat atcagaatgc ataaatatat ttaaatataa agattaaaaa gaatttaaag
     1681 gagtgttgat aacttatgat aattccatca agaagaatac aagatataac attaacaaat
     1741 ttaaaaaatg gtgaagtaac tttaattgaa ttggatgaaa tatacaagaa gatgggattt
     1801 ttatttgttg ttagtgaagg caaattgaaa aagataaaaa aggagaatca tcattagaaa
     1861 tgaatgaaat aataaatatt ataatagttt ataaaaccta acttatgtag aatataaata
     1921 cttaagttag gtttttttgt gataaagttt ataagtactc aattttataa gataaataat
     1981 ggtcttaagt gaaaagtaaa taagtttaaa ttttagtaag tattatattg cataagaggt
     2041 gatattatta tgaaaatagt aacctacaat attcataaag gtatggattc aaataataga
     2101 ttaactctaa ctaaaatggg gttatattta aaacaattgg attgtgatgt aatttgtttg
     2161 caagaagtat tatatcctca atttttagct ttaaaagctg ttttaaatat ggatggtgtc
     2221 tttgcgacaa atgtaaaaaa agtaaatatg atatatggta tttgtacatt tacaacatct
     2281 aaaatgttaa acagtaatca ttttttctta actagcaaaa aagaacaacg gggagctctt
     2341 tgtataacta tagatgcata tggaagaatt ataaatgtaa taaatactca cttgggactt
     2401 gataggcagg agagagcaaa acaattagac gaaataatag actataggaa cagattagtg
     2461 gggatagtta ttttatgtgg tgattttaat gagaaaaatg tctttttaag tatgtttaat
     2521 gatatggcta tttcactaaa caagtcttac ttaccaacat ttgaaaaatc aaactctaga
     2581 atagattaca tttttgttaa taaaaatact gaactaaaag gatacacagt agaaaaaatt
     2641 tacctgtcag accattatcc tgtaataggt tacatttaaa tttcaatata aatgaaatta
     2701 gttgttataa aataaacaat tttttgttaa gaaatagtaa aagaaatata ataaaaaata
     2761 tcaaaaataa aactaattat aagacataaa tttacaataa agttacattt gattaaattc
     2821 cttgtttaac aaaagctatt caaatataat ctaaggtagt tttgaaatgg gaactctatt
     2881 atgcaaattt aagctagtgt taaaatgagg tgaagttatg ggcagaagaa caacaagagt
     2941 ttcaagatta ggtaaagaaa aaaaacgaag tgttttaatt gtattggcag ctttagttct
     3001 aataatgggt ggatttactt atttttttaa cagtaaattt ctgtacaatg ggaaaatcgc
     3061 taaaaatgta tatatagaag gagtaaatgt atctgatatg actaaagcag aggcattaaa
     3121 agctataaca gataagtata ctccagaaga tttaaatctt gcttatgatg ggaaaaaata
     3181 tacaatatca ccaaaagata ttgatttaaa atatgataca gaagatgttg taaaagatgc
     3241 ttatgaaagt acaaaaaaag ggtcctattt tcaaaactta aaaaaatata ttgatataag
     3301 agtgaataag gcaaatatga agataaaagc tgaatatgat gaggcaaaac ttagttccaa
     3361 agtgtcttct atagcagata gtataaatgt taagatgaaa aatgcttcta ttagtgttgg
     3421 aagtggtgga ctaagttata cagactctgt tgtaggtaga gaatttgatt tggcagcaaa
     3481 taaagagtct atatataata tgataaaaaa taaagagcat aaaactttag aacttaaagt
     3541 aaatcttcaa aaaccagata taacaactga acaagtaaaa actgtaaatt ctgttatagg
     3601 tcaatattca actacttatt cacaagctgt agagggtagg tcatataatg taggattatc
     3661 agcaagaaaa actagtgatg tattattaat gccaggtgaa gaattttcat acaataaact
     3721 tacaggacct agtaataaag caaatggtta caaagatgca cctgttatag tttatggtaa
     3781 gctagaacaa tcagcaggag gaggtgtttg tcaaacatct tcaacagttt ataatgcggc
     3841 tcttctttcg ggtatggaga taactcaagt tacaaatcat tcatctgcat ctacttatgt
     3901 gcctaaaggg agagatgcta ctgtgagcga tggaggatta aacttaaagt ttaaaaatcc
     3961 atataagcat cctgtatata ttaaaaatta tgcaggtgga ggaagtgtat catcagtaat
     4021 ctatggtaat tctggtgaca aaccaaatat atctatagag gtaaaacaaa ctggtcagaa
     4081 taaatattct acatatcgaa tatttaaaga ttcaagtgga aaggtcataa aaaaagaaca
     4141 tatatcaaat agttcttata aagaattaaa aaaatagata attttttaga gaaatatttg
     4201 taatataaaa gggagtgtct caaaatgaac tttttagttt atgagacact ctttttctgt
     4261 gaaatcaaat atattttcat catttcaaca atacaaaaga agcgtatctc tattttgaga
     4321 cagccttttt tgtaaaaatt aacactatta gttcttgttt taatattaca atcattaata
     4381 tatagaaaat attcctatat attggtataa ttgtaaatag atttagttat ataaaatgta
     4441 tgaggaggtg acatggttga attttatagg caatagatat gaggtagtaa attctgacga
     4501 cgttttagaa attaacaaaa tctataaagc tagagatgtt ttttacagga aaaatgtgtt
     4561 aataaaagtt ataaagcaca ataattatat ctgtgaagat tttgtttcaa atttaattga
     4621 tgaaagtact gctttagatg agataaactc tccttatata ctaaaaataa tagatgttgg
     4681 gattcactgt acagaagaaa caacattata ttatgttgta agtgaagact ttaatggtat
     4741 cggactagat gaattaattc taggtaatta tcttcattta gaagcaattg taaacataat
     4801 gatacaagtt ttaaaagctt tagaaatgat acataggaat cattcatatc atggtagttt
     4861 aaaatcgagt agtataatag tagatacaga atacaatata aaaatttgtg attttggaat
     4921 tacaaaagca aataatgggg ttaatacaag aagctatgga aacaggagat atttatgccc
     4981 acatcaacta tgtataaatt atactgataa agaaagtgat ttttttgcaa caggtcttat
     5041 tctatttgaa tctatattta aaaaattgcc ttttggagaa tcaaattcag aagaaaaaat
     5101 gctacaatct attgataagg gattagattg gaatagtata aaagcaatta atggaaatac
     5161 tgaacttata aatgttataa aaaggcttct tggaagaaat aataagtata ctagagccaa
     5221 tgatattatt attgatttaa gtaaagtaat gtatgaaaaa gcatatatag aagttgaaga
     5281 tgagaaagaa gaagagcaga aacaagacaa agttatacaa gttaaaaaag aatataaaag
     5341 taaaatgaga aaaaaattac ataaaaaact tgttgttgcc ggtctagcta tagtcatgat
     5401 ttcaatgatt attattagtt ccataatata aaaattgtat attaagtatt ttaaaatcaa
     5461 tgtctataaa ggatatacat agaaatttta gtgtagtctt aaattatgaa aggaagtggt
     5521 tattatgtta acaaaaaata atgaggtatt aaacgtctag gagtatttta acaaatagcc
     5581 acctgctttt acagtttaga ataaaaaagc tgtggctaaa ggtcacagct ttttgctact
     5641 ttttaaaggc aggagaatat taaaaaggag caaattatga gcaatataaa aataatagca
     5701 agtaataaat gttggattga agatatagca aggaaacaac ttgaagatat ttcaaagtta
     5761 aatggaattt taagagtagt aggattacct gacttacatg caggtaaaat acctgtaggt
     5821 ttagcagttg agactaaaaa tattatttat ccacatataa ttggaaatga tataggatgc
     5881 ggaatgactt tatttaaaac tggggttcta aaaaagaaat ttaaaaaaga caaatggatt
     5941 aagtcactta gtaagattaa agatttgtct gatatagaaa taaaaaacac atataaagaa
     6001 gaatgtccaa ttttaaattt aggaactata gggagtggaa atcattttgc agaaattcaa
     6061 tgtataagtg aaatttataa taaagaacaa tttgaacaat taaaattttc atctgatgat
     6121 attatgatgt tagttcactg tgggtcaaga aattatggag aagatatttt aaaaaaattt
     6181 tatgataaag atggacttga agttgaaagt gagaaagcta tagattatat taaaaaacat
     6241 gataatgctt taatgtgggc agagcgtaat cgtgaagcta tcagtaaaaa aattatgcag
     6301 tcaataggta catctggaga tgttgaaaca atattctcta taaatcataa ttttatagag
     6361 aaaagggaag ataaatttat acatagaaaa ggtgctgttt caagtgaaag aggagctgtg
     6421 attataccag gttcaagagg cagtctatca tatatagtta tgcctactga aaatacagag
     6481 atatctttat attctctatc acatggagca ggtagaaaat ggtctcgttc agtttgtaaa
     6541 tctcgcctta aaagtaagta tagtaaagat actataaaac aaactaaatt taaaagtcag
     6601 attatatgta atgatgtaaa tttattattt caagaagctc cagaggcata taagaatata
     6661 gagcagatta ttgaaagttt gatagaatat gaacttattc aagtagtggc aactatgaag
     6721 ccattgatta cttataaagg ataattttta aagttaaaaa agattaaaat tatattataa
     6781 atagctaatt ttatggaaca tttaaaagtg ttttattatt agctattttt ttattttgta
     6841 gagacgataa tttatagagc taaattcttt gatatataat gattacaaag ttagactgta
     6901 ttggaaactg cacatacatg aattgatgac aatataagtg attcccaaat ataaatgaaa
     6961 gtataagctt atttttacta taaaaatttt cactgtacaa aaacattaat gacattattt
     7021 ttattgacat aaatatataa tttatggaat aatattagaa gcactgatat aagtgtttaa
     7081 ataagaatag aaaaggagaa gtgttttatg aaaaaaaata ctaacattaa tgagtccgga
     7141 gttaaacttc ttaataaata aggagtttga tatataataa ctccttattt attaagttgt
     7201 tcgcaaaata actattatca aagtaaatga tagggtgatt taaaagacga tgacttataa
     7261 ataaaggaga aaaaataatg aatagtaata catttgaaag attacaacta aatgaagtta
     7321 aagacttaat aaaaatacat tgtgtaagtt cgctaggaaa aaatttaata gataaattaa
     7381 ctcctagtgg gaatattgga gtagtaagaa ggaaattagc agaaaataaa gaagctagaa
     7441 agataattga aaatagtaat cacataccac ttgaaggatt gtttaatgta ggttctacaa
     7501 tagataaaat tgaaaaagga atgataatag aacctgttga acttgtaaat attgaagatt
     7561 ttttaagagg ttgtaggaag atgaaagctt ttatgttaga aaaagaattt tattcaccta
     7621 cattaagttc ttatgcctta aatataacag aatgtaaaag tatagaagat gagataaatt
     7681 actgtataaa atctaataaa gttgattcta atgctagtaa agaattaaaa aagataagac
     7741 gaaatataga aattacagaa ggaaagataa aagatagatt aaataaattt ataacatcaa
     7801 ctgtaaataa aaagtatata caagagttta taataagtaa aagaaatgat agatatgtaa
     7861 taccaattaa atcttcttat aaaaatgaag ttaatggtac tatattagat acatcatcaa
     7921 aaggaaatac tgtatttatt gaacctatta gtgtttcaaa tttaagtaca gagttaacta
     7981 tgctaaaagc tgatgaaact attgaagaat acaaaatatt atcttattta acagaactta
     8041 tatttgagaa gataagtcag ataaaattaa atatagagat actttcagaa tacgatatgg
     8101 tatttgcaaa agctaagtat agtcaaaaaa taaaaggaat tactccaaaa ataaataata
     8161 atggctatat aaaaataatt aaaggtaaac atccacttct aacaggagat gcagtacctt
     8221 tagattttga aataggcaaa aattatagaa gtcttataat aacaggtcct aatgcaggag
     8281 gaaaaactgt aacccttaag actgttggtt tactaacttt aatggttcaa tgtggatttg
     8341 atatttctgc aaaagaaggt agtgaattta gtgtatttga aaaagttttt gtagatatag
     8401 gggataatca aagtattgaa aatgccttaa gtactttttc atcacatata aaaaatattg
     8461 cagagattat gagtttatca aataattcta ctcttgttct gtttgatgaa ataggaagtg
     8521 gaactgaacc taatgaagga gctggtttag caatatcatt attagaagag ttttacaaaa
     8581 tgggatgtat aactatagca tcaactcatt atggagagat aaaaaagttt gctacattgc
     8641 atccagaatt tgaaaatgct ggtatgatgt ttgataaaga aacgttagaa ccattgtata
     8701 agttaactat tggaaaatct gaagatagta atgctctttt tatttctaaa aaaatgggaa
     8761 taaaaaatag agttttagat agagctaaag aatatgtaat tgatagaaac tacaatttag
     8821 atttagttaa aagaagtaag ctacaatcta atattgaaga taaaaatagt tctgaagtca
     8881 ttttaaacta tacagattat aatgtagggg ataaggtaaa attactagat gaagatgatt
     8941 ttggaattgt atataaacct atggacaagt ttaataatgt agaagtattg tttaatgata
     9001 attttatttc agtaaatata aaaagattac aacttagcat aaaagcatca gaattgtatc
     9061 cagaagggta tgatttagat gtattattta ctagttttaa agaaagaaaa ttagaaaaag
     9121 atattcaaag aggttcaaaa aaagctctta aaaagattca gaaagaaatt agagagaata
     9181 gaaaataaat ataaaaagca caaaagaaag caatctaaag agaaaagttt atctttagat
     9241 tgctttctta ttaacatatc ttcataaatc caatgactaa caagattaaa ccacttaacc
     9301 aagataagtt taaatttacg tttttaacaa acatatttcc tagtaaacaa ccaagtaata
     9361 ctgcaattat atttgatatt aaagaaaata gaataacttg tatataattc acacctacaa
     9421 ggccactacc aaaaccgata gctaatccat ctaaacttaa agcaagtgca agtgtaaatg
     9481 cttcagcaga tttaagcact ttagatttac ttgtatctaa gacatcaggt tcgatactta
     9541 cattaaaatt taatttaagg tctaacatat taaaattata attctttgag tgtatagatt
     9601 ttttcttaaa ataagattta aaaaaacttt caattagtct agcacttcct aataaaaata
     9661 aaataaagaa acatattaac attgttatat tttgaggtaa aaagtctcta actattgtac
     9721 ctgcaaaaag cgatattgct aaaatagctg aacaaactac gctgataatt atatttgaat
     9781 ataagggaac tttaacttta tttacgccat atccaaagct tgtcacaaag gcatctatac
     9841 aaagagaagt aactaataaa attgattcaa tcacagtaga ttaacatcct ttctcttaaa
     9901 ttttgtactt atattagtta tagtattgta aaaatggata aattgttaca gataatccaa
     9961 taaattgttg ataaaattcc aacatcatac aacacctaaa taacaaaaga atcatatcat
    10021 ataataatat aaaaccaatc ataataaagc gggtgaaaat aatggaacaa aataataagg
    10081 ttgggaattt cggtgatttg ttgaagattt tattagatga aaaagaatta tcaatgggag
    10141 aactaagtaa aaaaagtgga attgataaat ctactatatc tcgtatagct aataataaac
    10201 aaaagccaaa tataaatcat ttagaaaaga tggcaataca tttaaatatt aacctagaag
    10261 aactgttgaa agcttcagga tatgaattta gaaacagcaa taatcaaata tttaatgcag
    10321 atagtgattt tagtaacttt gatgatattc ttggatttgc aaatttaatc aatgataaga
    10381 actttaatgg aaatattgaa aaagagttaa gtaagtgtaa gttatatgtc caaacagatg
    10441 aaggtaaaaa attacttttt gataatttta ataaaaaaat agattctatt gaaaaacaag
    10501 gtcaatttac agatagatta agacaaatgt atgctgattt ttgtacagat ggacttacaa
    10561 taaagaaata tttattgatt ggaagtatgc tactttattt tgttatatca acagatgtga
    10621 ttccagactt cgtattccca ataggattta tggatgattt agtagcatta aatatagtta
    10681 caaaattact taaaaatgat aagtaagttt tagaatcata tttaatatat aaataaatca
    10741 aagtatataa aatttattat tttttatatg aaacaaatta aaagcacaat gaagtagatt
    10801 aaaaattt
//
LOCUS       DAMJWC010000103        10662 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMJWC010000103 DAMJWC010000000
VERSION     DAMJWC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.108"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            89..436
                     /locus_tag="PC503_003349"
     CDS             89..436
                     /locus_tag="PC503_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2529304.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(586..1086)
                     /locus_tag="PC503_003350"
                     /pseudo
     CDS             complement(586..1086)
                     /locus_tag="PC503_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(1113..2618)
                     /locus_tag="PC503_003351"
     CDS             complement(1113..2618)
                     /locus_tag="PC503_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2529305.1"
                     /translation="MNVAIYLRKSRADEEAEHRGEFETLSRHKTTLLKLAREQNLNVI
                     EIKEELVSGESIEYRPKMLELLGEIKNNNYDAVLVMDIDRLGRGNMQDQGLILDTFKK
                     SKTKIITPRKTYDLNDEFDEEYSEFEAFMARKELKLISRRMQRGKIKSIEEGKFIAQA
                     PPYGYDIKYLNNKERVLVINEDKATVVKIIFDMYLKGDGACKISNYLNELGYKTTTGR
                     TWYEKGIRDIIKNKVYCGYIVWNKVERKRNSSRTRGIEEQIEVKGKHEPIISEDIWNK
                     AQNIRKKRINSPTPNNKITNPLAGIVKCGYCNHTLIAKSNTTSNGYEKYMVCTNCKNK
                     ATKLYILENKILEVLNKWLVNYRLSLKDEKDNSKPENTLEHTLINLNKELDTLEKQKE
                     RLHDFLEQGIYDSNTFGERLKILLSRIENAREAINKTNIDIEMQKERNTVKTQIVPQL
                     EKILSEYTEEKEPYLKNILLKSVINYAVYKKEPNQKSDDFSLILYPNIPRD"
     gene            complement(2817..3671)
                     /locus_tag="PC503_003352"
     CDS             complement(2817..3671)
                     /locus_tag="PC503_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2529306.1"
                     /translation="MEWIERLNKAINYIEENITKEIEYEQVAKIACCSTYHFQRMFAY
                     MADVPLSEYIRRRRMSLAAVELQNDDKKIIDVALKYGYSSPTAFNRAFKSIHGVAPSV
                     IKKREITTLKAFPPISFKISIKGAEEMNYRIEKKEAFRIVGVSQPLHNELEKNFEIVP
                     QMWQKVALDGTLQKLIPMMDSQLQGVLGISICNNSEEWKYFISVSSTKSIDNTLEEYT
                     VPAFTWAIFSGEGQCPQAIQELEKRIVTEWLPTSGYEYDNGPDIELYLNPDPQNAKFE
                     VWIPVVKK"
     gene            4056..4337
                     /locus_tag="PC503_003353"
     CDS             4056..4337
                     /locus_tag="PC503_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529307.1"
                     /translation="MPNIEKDLDGTTTITYLNDDIGVPTDENGYKISMTILHGKTICH
                     VVSPETILGRKFTLEEKQEKDTIIYGAIEKIMVDRQLQIKNSNKEVASH"
     gene            4487..5335
                     /locus_tag="PC503_003354"
     CDS             4487..5335
                     /locus_tag="PC503_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HDF2529308.1"
                     /translation="MIKSFLMLGQSNMAGRGFISEVTPIYNERIQMLRNGRWQMMTEP
                     INYDRPVSGVSLAASFADAWCCENQEDRIGLIPCAEGGSSLDEWNIDGILFKHAISEA
                     KFAIQSSELTGILWHQGENDSNNGNYKFYYKKLLSIIETLRKELNIPDIPIIIGGLGD
                     FLGKVGFGKSCTEYVFINQELQKFAFEQDNCYFVTATGLTSNPDGIHIDAISQRKFGL
                     RYFEAFHKKKHIMEALANESELIIPSNSKTYTKTEKIYINSMDLALGKISYDEFESKL
                     IKLNDN"
     gene            5387..5908
                     /locus_tag="PC503_003355"
     CDS             5387..5908
                     /locus_tag="PC503_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529309.1"
                     /translation="MIPLLILGLLKQNPNSYGYELLALMEKKHYKYIVNFTKGSFYYN
                     LQQLEEKKFIEKVENKQSNKNRETHNYIITELGCQEFEKLMYKYGSKTEYINLSFYAT
                     LLFANDYKNEKLIELLETQIKQTQVRISLLNESIENDKTNSHYFNRMLENSRSHHLVN
                     IEWFEKLLNDIRD"
     gene            6259..6792
                     /locus_tag="PC503_003356"
     CDS             6259..6792
                     /locus_tag="PC503_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDF2529310.1"
                     /translation="MTEVIIVNDARIISQIKAGKKELFDTLIKKYYDSIYCYCYRHVD
                     NKMTAQDLTQDVFVTVINNIENYKHYGKFENYLYVIAKNKCKDFWKKKQPIYLESLDK
                     EISNQELSDIENKMFIKEALTKLPELEFEVIILRYYHDLRFKDIAKIMESSVSVTKYR
                     MSRALKKLELYLEGGKL"
     gene            6789..7550
                     /locus_tag="PC503_003357"
     CDS             6789..7550
                     /locus_tag="PC503_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529311.1"
                     /translation="MNNKEIKRSLQKYKVPKYDSSALEKTIKTIHELTLSNTYKRMNN
                     KDFFISQIGFIRKRTWIMQFLILCTICIFLFSTSADSNSFYNSLSLISIASPLFVLTN
                     IEELTKVYNSSILEIEFSTKNTLHKIIATRMLIFGISDLLFMIIILVSAKQIIDVNIL
                     YIIIYILVPFNLMCIGCMEIINRNKGKHTNYYCMIYGISLVLLIVTLSNFRDNLYQFE
                     AINQWLIVFLVTAVTLIYEIRKTWRHLCSFENIII"
     gene            7588..8454
                     /locus_tag="PC503_003358"
     CDS             7588..8454
                     /locus_tag="PC503_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529312.1"
                     /translation="MELSVERLTKQYNNKIIVDKIDFKLNEGIYGFLGENGAGKTTLM
                     RMICGILSPTSGEVKVDGKNNLDMGEDFRDMIGYLPQNFGYYPDFTAKEFMLYIASLK
                     GLMPSYAKRKTQELLEMVGLSEVINKKIRTFSGGMKQRLGFAQTLLNDPKILILDEPT
                     AGLDPKERVRFRNLISEFSKEKIVILSTHIVSDVEYIADKILIMKKGRFVLTGSIEEV
                     TSKIKDKVWKCVVNENEIDYMSDRYCLANIHHSGGVANLRIVSDIKPHDNACNLKPTL
                     EDLYLYCFNEVL"
     gene            8475..9716
                     /locus_tag="PC503_003359"
     CDS             8475..9716
                     /locus_tag="PC503_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529313.1"
                     /translation="MSTLIKFELKKIIKRKSTIAVILGSLFLSIILFALMPIQEKAND
                     ESGKEYRGLQAIELKKQQSKLNEGYITDKKVKNSIRDYQKMFNNPNNITTDEGGFSNF
                     KPDIYWKFFYPNKAFYNFIIESYSNPNDYNPEIIKSMPLEDGVNFYKFRNEKVNTILN
                     MEYPDKNYTQKEKDFWLSKNKDIEEPYLNGYYQGWNYFLLARDLLIFTIVAVCISTAS
                     VFSGEYQSGADSIILSSKYGKTKVITAKIVSSFLFGTIIFTINTIVSIGILLLSFGID
                     GWNLPLQLTTSSIPYPYTFLQAILLSVLIIYMILILLISFTLLLSSYMKSPFPVLITN
                     IILLFVPIFLKYSETNKLYNQILNVLPSNAISFSFTNYVDYKFGNLIIALPTMIIFTC
                     LVLTVVFLPFIKNNFKKHQVN"
     gene            complement(9940..10512)
                     /locus_tag="PC503_003360"
     CDS             complement(9940..10512)
                     /locus_tag="PC503_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2529314.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQKSV"
BASE COUNT         3935 a         1368 c         1463 g         3896 t
ORIGIN      
        1 tttattccta ttgtgtaaag tgagaatact attttcttat attggtataa taatagtaaa
       61 tctaatatag aaaagaggta tttctagtat gcatgaaaat aaaaaaaatc tattagacgg
      121 aagcttagct caatataatg atacagcagt tccaaaaata ccagtatttg ctggtaacga
      181 tataacttca gaagtttatt attttaaacc taatcaagtt cttaatgctc atagacaccc
      241 taatggtgaa caaatatttg tgttcctaaa aggagaaggt aaaatgaaac ttggtgagca
      301 tgaatgtgat gtaaaaaacg gcgatactgt atttgtacca acaggagagt ggcatgaaat
      361 tactaatgga agcaatgaag aaatggtagc cgttcaaatt acaaaaatta atgctggagc
      421 agaatacaga ggatagatat ataagtacag ttagtacttt aatatctatt ttattatata
      481 aactttaatc tcaaatataa aaagagtctt ttaaaaggct ctttttatat ttttgttaat
      541 tttcattata aaaacaagaa aatatctagc taaaactaat atattttatt taatattttt
      601 tatagcattg tttgcaaact cagtatttac gatatcttta taaggtgctt ccttatctag
      661 ttctttagct tctttcataa cagtcatcaa tttcttcaaa ccttcctctt ttaatacagg
      721 attttgagac catgcatcta ttgatttata tctatctaca actgttgtta aatcttctaa
      781 agatatatct tcaaagaaag gttgcatagc cttagctact tctttgctag atgcttgttg
      841 aatccataat tgacctttat aaacagcatt tgtaaatctt tgaattaaat ctttattgtt
      901 tttcatgtat gatctcgtag tagagtatgc tgtaaaaggt atttctccag aatcttttcc
      961 tatagatgta actatatatc cactaccttc tttttccatt gctgttgctg taggttcaaa
     1021 tgctgttgta aagtcaccct ctccacctgc aaaagctcca gccattacac caaattggta
     1081 atcagtctat ttataacatt taaaacatat aattaatctc ttgggatatt agggtaaagt
     1141 attaaagaaa aatcatcaga tttttgatta ggttcttttt tatagactgc gtaatttatt
     1201 acacttttaa gcaatatatt ttttagataa ggttcttttt cctctgtata ttcacttaaa
     1261 attttttcaa gttgaggaac aatttgtgtt ttaactgtat ttctttcctt ttgcatttca
     1321 atatctatat ttgttttatt aatagcttct cttgcatttt ctatacgaga taagagtatt
     1381 tttaaacgtt ccccaaatgt attactgtca taaattcctt gttctaaaaa atcatgtagt
     1441 cgttcttttt gtttttctaa agtatccaat tctttattta aatttatcaa ggtatgttct
     1501 aaagtatttt caggtttaga gttgtctttt tcatctttta aagatagtct ataatttact
     1561 aaccatttat ttaagacctc taatatttta ttttctaata tgtatagttt agtagcttta
     1621 tttttacaat tagtacaaac catatatttc tcatatccat ttgatgtagt attagatttg
     1681 gctattaaag tatgattaca gtatccacat tttacaattc cagccaatgg atttgttatt
     1741 ttattgtttg gagtagggga attaatacgt ttttttctta tattttgtgc cttattccat
     1801 atgtcttcac ttattattgg ttcatgcttt ccttttacct caatttgttc ctcaattcct
     1861 cttgttctac tagaatttct tttcctctcg actttattcc atactatata tccacaatac
     1921 actttgtttt ttataatatc tcttataccc ttttcatacc aagttctacc tgttgtggtc
     1981 ttataaccaa gttcgtttaa ataattggat attttacatg caccatctcc ttttaaatac
     2041 atatcaaaga ttattttaac aacagttgct ttatcttcat ttattacaag tactctttct
     2101 ttattattta aatatttaat atcataccca taaggaggag cttgagctat aaatttaccc
     2161 tcttcaatac ttttgatttt tcctctttgc atacgtctag atattaattt taattcctta
     2221 cgagccataa aagcttcaaa ttcagaatac tcctcatcaa actcatcatt taaatcatac
     2281 gtttttctag gagtaataat tttcgtttta gattttttaa atgtatctag tattaaccct
     2341 tggtcttgca tattaccacg acccaaacgg tcaatatcca tcactaaaac agcatcatag
     2401 ttattatttt taatttcacc tagtaattct agcatcttag gtctatattc tatactttcc
     2461 ccagaaacaa gttcttcttt aatttcaatg acatttaaat tttgttctct tgctagtttt
     2521 aaaagagttg tcttatgtct acttagagtt tcaaattcac ctctatgttc tgcttcttca
     2581 tcagctctgc ttttgcgtaa ataaattgcc acattcatta aatcacaccc cttgaatata
     2641 ttatattcag taacagattg attatattta aaacacaaaa ataaaccttc aaaatacaag
     2701 atatattttt taggtttatt tttatacagt aaattttata gtatatttaa aagcttgtaa
     2761 tctaagtaaa tatttatact attaatttta tgctttcttc attttttaat tttaaactat
     2821 ttttttacta caggtatcca tacttcaaat ttagcatttt gagggtctgg atttaagtac
     2881 agttcaatat caggaccatt atcatattca taaccagaag taggtaacca ttctgttaca
     2941 atacgctttt ctagttcttg tattgcttgt ggacattgtc cttctccaga aaatattgcc
     3001 caagtaaaag ctggaacagt gtattcttct aatgtattat ctatagattt tgtacttgaa
     3061 acagatataa aatacttcca ttcttctgaa ttattacaaa tacttatacc taatacacct
     3121 tgaagttgac tatccatcat agggattaat ttttgaagcg ttccatctaa agcaaccttt
     3181 tgccacattt ggggaacaat ttcaaaattc ttttctagtt cattatgaag tggctgagat
     3241 acaccaacta tacgaaatgc ttctttcttt tcaattctat aattcatttc ttcggctcct
     3301 ttaatactaa ttttaaaact gattggagga aaggctttta aagttgttat ttctcttttt
     3361 tttataactg atggggcaac accatgaata cttttaaatg cacgattgaa tgctgttgga
     3421 gaagagtatc catattttaa agccacatca attatctttt tatcatcatt ttgtaattct
     3481 acagctgcta aagacatccg tctacgacga atatattcag aaagtggtac atctgccata
     3541 taagcaaaca ttctttgaaa atgatatgta gaacaacaag ctatttttgc cacttgttca
     3601 tactcaattt cttttgttat gttttcttca atatagttaa ttgctttgtt taatctttca
     3661 atccattcca taaaatcagc tccttgtaat ttatataata tctattttaa aatagttaat
     3721 cctctctttc tatgcactaa ttaactagct taataaagaa tgaacatgag aaagtctgta
     3781 attaactaca aaaatgaaca aatagtattg tttttcacat taaagtatat cacaaattag
     3841 tatctaattt ttatataaga taacagtttt aatttattat gaaattttta taatatttta
     3901 gcttagacat ttaattatat ataacatttt atttatagtt aactattttt gaagtttacc
     3961 cttaatcaag caacacttag ttattcaatt ataaataatg attgagaata ggacaatttt
     4021 taagatacat aaaatataaa gaggagggga tttaaatgcc aaacatagaa aaagacttag
     4081 atggtacaac tactataaca tacctcaacg acgatatagg tgttccaaca gacgagaatg
     4141 gatataaaat atctatgaca atactacatg gaaagacaat ctgccatgta gtatctcctg
     4201 aaacaatctt aggaagaaag ttcacattag aagaaaaaca agaaaaagat acaataatat
     4261 atggagcaat agaaaaaata atggtagaca gacaattaca aataaaaaat tcaaacaaag
     4321 aagttgctag tcattagcac ttctttaata agtaaagtag gacaagtatt ttttataata
     4381 ttattgactt atagtctaat tagactataa tataaacata gatagtctaa ttagactact
     4441 attaaaaata aatacaataa gaatttaaga aaggataata ataataatga ttaaatcatt
     4501 tttaatgtta ggacagtcca atatggctgg aagaggattc ataagtgaag tgactccaat
     4561 ttataatgaa agaatacaga tgttacgtaa tggaagatgg caaatgatga cagaacctat
     4621 taattatgac agaccagttt ctggggtaag tcttgctgca tcatttgcag atgcatggtg
     4681 ctgtgaaaat caagaggata gaattgggct aattccttgt gctgagggag gcagttcctt
     4741 agatgaatgg aatatagatg gtatactttt taaacatgct ataagtgaag ctaaatttgc
     4801 catacaaagc agtgaattga caggaatttt atggcatcag ggagaaaatg acagtaataa
     4861 tggcaactat aaattttatt ataaaaaatt actttctatt attgaaactc ttagaaaaga
     4921 attaaatatt ccagatatac caattattat tggtggattg ggagacttct taggaaaagt
     4981 aggttttgga aaaagttgta ctgagtatgt atttatcaat caagagttac agaaatttgc
     5041 ttttgaacaa gataattgtt actttgttac agcaacaggt cttacatcta atcctgatgg
     5101 tattcatatt gatgcaatat ctcaaagaaa atttggatta cgttattttg aagcttttca
     5161 taagaaaaag catattatgg aagcattagc taatgaaagt gagttgataa taccgagtaa
     5221 ttccaagaca tatacaaaaa cagaaaaaat atatataaat agtatggact tggcactagg
     5281 aaagatatca tatgatgagt ttgaatctaa acttattaaa cttaatgata attagataaa
     5341 atattcatta atatactaat aaatatagat tgaaagaggt gattttttga taccattatt
     5401 aattttagga ttattaaaac aaaatccaaa ttcttatgga tatgagttat tagcattaat
     5461 ggaaaagaag cattacaagt acatagtaaa tttcactaaa ggttcttttt attataattt
     5521 acagcaactt gaagaaaaaa agtttattga aaaagttgaa aataaacaat ctaataaaaa
     5581 tagagaaact cataactaca taattactga acttggatgc caggaatttg aaaaattaat
     5641 gtataagtat ggttctaaaa cagagtatat aaatctatca ttttacgcaa cactattatt
     5701 tgcaaatgat tataaaaatg aaaagttaat agaattattg gaaacgcaaa ttaagcaaac
     5761 tcaagtaaga atttctctat taaatgaatc catagaaaat gacaaaacaa attcacatta
     5821 ttttaataga atgctagaaa attctcgttc tcaccattta gttaatattg aatggtttga
     5881 gaagttgcta aatgatatta gagattgatt ttaataataa aaaaacatac atatatattt
     5941 tatataaatg tatgatatat agattaaaaa taaggcagat aattttcaat tgaatatctg
     6001 tctttttgtt atataagatg ttaaaagaaa cttatactat gtaagtaaaa tttataaata
     6061 taaagttgtt cattgttgaa ttacagacac ttaagatgaa aagtatgaca tttgatataa
     6121 taaaattgtt taagtattaa ttatgagtat taattaatgg tatagataat tttaatataa
     6181 ctgtatttat aaataattat aaaataataa attaattttt ttatactgac ttttttatag
     6241 tataaatcgt tatatataat gacggaggtg ataatagtga atgatgctcg gattatatca
     6301 caaataaaag caggaaaaaa agaattgttt gatactctaa taaaaaaata ctatgatagc
     6361 atctactgtt attgttatcg ccatgtagac aataaaatga ctgcacaaga tttaactcaa
     6421 gatgtatttg taacagttat aaataatata gaaaattata aacattatgg taagtttgaa
     6481 aactatttgt atgttattgc aaaaaacaag tgtaaggatt tttggaagaa aaaacaacca
     6541 atatatttag agtcattaga taaggagata tcaaatcaag aattatctga tatagaaaat
     6601 aaaatgttta taaaagaagc tttgactaaa ttaccagaat tagaatttga agtgataatt
     6661 ttacggtatt accatgattt aagatttaag gatattgcta aaattatgga gtcaagcgtc
     6721 tctgtcacaa agtacaggat gagtagggca ttaaaaaaac tagaattata tctggaagga
     6781 ggtaaattat gaataataaa gaaataaaaa gaagtctaca gaagtataag gttcccaaat
     6841 atgattcttc agctcttgaa aagactatta aaactataca tgagttaacg cttagtaata
     6901 cttataaaag aatgaataat aaagactttt ttatatctca aattggtttt ataagaaaaa
     6961 gaacttggat tatgcaattt ctaatactat gtacaatatg tatattttta tttagtacat
     7021 cagcagatag taattcattt tataatagtt tatccttgat ttctatagca tcaccacttt
     7081 ttgtactgac aaatatagaa gaattaacaa aagtgtataa tagtagtatt ttagagatag
     7141 aattttcaac aaaaaataca ttacataaaa ttattgctac tagaatgctt atatttggaa
     7201 taagtgattt attgtttatg attattattt tggtatctgc aaaacaaatc attgatgtaa
     7261 acattctgta tataataatt tatatactag ttccttttaa cctaatgtgt ataggatgta
     7321 tggaaattat aaatagaaat aaaggtaagc atacaaatta ttattgtatg atatacggta
     7381 tatctcttgt attattaata gttacactga gtaactttag agataatcta tatcaatttg
     7441 aagcaataaa tcaatggcta attgtttttc tagtcacagc agtaacatta atatatgaaa
     7501 taagaaaaac gtggagacat ctttgttcat ttgaaaatat tattatctaa gtaaaaaata
     7561 agaatacaca gtatcaggag gaatagtatg gagttaagtg tagaacgttt aacaaaacag
     7621 tataacaata aaattatagt agataaaatt gactttaaat taaatgaggg tatatatgga
     7681 tttttaggag aaaatggagc tggaaaaaca actcttatga gaatgatttg cggaatatta
     7741 agtcctacat ctggagaagt aaaggtggat ggtaaaaata atttggatat gggagaagat
     7801 tttagagata tgattggata ccttcctcaa aactttggat actacccaga ttttactgcc
     7861 aaagaattta tgctatatat agcatcatta aaaggattaa tgcctagcta tgcaaagaga
     7921 aaaacacaag aattattaga aatggtagga ttatcagagg taattaataa aaaaataaga
     7981 acattttctg gaggtatgaa gcaaaggcta ggatttgctc aaacactact taatgacccc
     8041 aaaattttaa tattagatga gccaacagca gggctagacc ctaaagaacg agttagattt
     8101 cgcaacctaa tttcagaatt ttctaaggaa aagattgtta tattgtctac tcatattgtg
     8161 tctgatgtag aatatattgc agataaaatt ttaataatga aaaaaggaag atttgtttta
     8221 actggctcaa tagaagaagt aacttcaaag ataaaagata aggtatggaa atgtgtggtc
     8281 aatgagaatg aaatagatta tatgtctgat agatattgtt tagcaaatat ccatcattct
     8341 ggtggagttg caaatcttag aattgtaagt gatataaagc cacatgacaa tgcatgcaat
     8401 ttaaaaccaa cattagaaga tttatattta tattgtttca acgaagtact ataaatatac
     8461 ataaggagat aggtatgtct acattaatta aatttgagtt aaaaaaaata ataaaaagaa
     8521 agtctacaat agcagttatt ttaggaagtt tattcttaag catcattctt tttgcattaa
     8581 tgccaattca ggaaaaagct aatgatgaaa gtggaaaaga gtataggggt ttacaggcta
     8641 ttgagctaaa aaagcaacaa tctaaattaa atgagggata cataacagat aaaaaagtaa
     8701 aaaactcaat cagagattac caaaaaatgt ttaataatcc aaataatatt acaacagatg
     8761 aaggtgggtt ttcaaatttt aaaccagata tttattggaa attcttctat ccaaataaag
     8821 ctttttataa ttttataata gagtcatata gtaatccaaa tgattataat ccagaaataa
     8881 ttaaatcaat gcctttagaa gatggagtta atttttataa atttagaaat gaaaaagtaa
     8941 atacaatatt aaatatggaa tatcctgata aaaattacac acagaaagag aaagattttt
     9001 ggttgtctaa aaataaggat atagaagagc cttatttaaa tggatattat caaggatgga
     9061 attattttct attggctaga gatttactaa tttttactat agtagctgtc tgcataagta
     9121 cagcttctgt attttcagga gaataccaat ccggtgctga ttcaataata ttatcttcta
     9181 aatatggaaa aacaaaagtt ataacagcta aaatagtaag ttccttttta tttggtacga
     9241 ttatttttac aataaataca attgtgtcta ttggtatact tcttttatct tttggaattg
     9301 atggatggaa tttaccatta caacttacaa ccagttcaat tccataccca tatacatttt
     9361 tacaggcaat attactaagt gtgttaatta tttatatgat attaatacta ttaattagtt
     9421 ttacactttt attatcatct tatatgaaat caccttttcc agttttaatt acaaatataa
     9481 tattactatt tgtaccaata tttttaaaat atagtgaaac aaataagttg tataatcaaa
     9541 ttctcaatgt tttaccatca aatgctattt cattttcatt tactaattat gtagattata
     9601 aatttggtaa tttaataata gctttaccta caatgattat ttttacatgc ttagttctta
     9661 cagttgtttt tttacctttt attaaaaata attttaaaaa acatcaagtt aactaaaata
     9721 tatattataa aaagaaggtg tcttaaaatg aactttttag cttattaggc actcttcttt
     9781 gtattaattt aaatatattt tagtattaga ttaaatatgt tttcatcatt ttaacaatga
     9841 aaaagagctt tatctctatt ttgagatagc tcttataaag ttaaatatta aattgataac
     9901 tataaaatat gtagtttgaa tttataattt gtgttataat catactgatt tttgtacatc
     9961 agttcttaca ttaacattgc ctgcttttag attttctcca atagtaagac ctttttcttt
    10021 tagaacatat tcaaaagtca ttagtggaac tccacctttt ctaccaccta atatttcggt
    10081 tccttttaaa tcattgtaag agaaattagg catttttttc ctagcaacta gaaaactacc
    10141 atctcttttt gtcaattgag caaagttcac tgcataatcg tttttgtttt gattatatac
    10201 atatatagat gcttcaggac ccattaaacc tacgtttgct tcacctgaaa tcaaagctgc
    10261 catagtttta tctgcacctt gggtatttat aaggtcaatc tttatacctt catcttcaaa
    10321 gaatcctttc gtaatagcag catactgtgg agcataaaaa acagagtgag taacttctgc
    10381 tatagttact ttatccagat ttttagacga agaagattca ccttttttgt cattagagtt
    10441 aaaatcacat ccagttagac atattgtact tacaatgata gagcttgcta ttgcgactat
    10501 ttttttaaac ataataaata cctcccataa gacatacgaa tagtatatag tattaaaaat
    10561 ttattgtagt tgttacaaaa atgtatctat gcttataata tttctacaaa aacttaataa
    10621 taattttcag ctttatgttt agttttttca gtaatgtgta at
//
LOCUS       DAMJWC010000104        10605 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMJWC010000104 DAMJWC010000000
VERSION     DAMJWC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.109"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(147..716)
                     /locus_tag="PC503_003361"
     CDS             complement(147..716)
                     /locus_tag="PC503_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2529315.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            919..1146
                     /locus_tag="PC503_003362"
     CDS             919..1146
                     /locus_tag="PC503_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2529316.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(1365..2108)
                     /locus_tag="PC503_003363"
     CDS             complement(1365..2108)
                     /locus_tag="PC503_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2529317.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            2276..3148
                     /locus_tag="PC503_003364"
     CDS             2276..3148
                     /locus_tag="PC503_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2529318.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            3148..3813
                     /locus_tag="PC503_003365"
     CDS             3148..3813
                     /locus_tag="PC503_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2529319.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            3834..4691
                     /locus_tag="PC503_003366"
     CDS             3834..4691
                     /locus_tag="PC503_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2529320.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(4847..7393)
                     /locus_tag="PC503_003367"
     CDS             complement(4847..7393)
                     /locus_tag="PC503_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2529321.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGISDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVISKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(7393..8079)
                     /locus_tag="PC503_003368"
     CDS             complement(7393..8079)
                     /locus_tag="PC503_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529322.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(8162..9151)
                     /locus_tag="PC503_003369"
     CDS             complement(8162..9151)
                     /locus_tag="PC503_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529323.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(9138..9824)
                     /locus_tag="PC503_003370"
     CDS             complement(9138..9824)
                     /locus_tag="PC503_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529324.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(10324..>10605)
                     /locus_tag="PC503_003371"
     CDS             complement(10324..>10605)
                     /locus_tag="PC503_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529325.1"
                     /translation="KSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGND
                     STRDGFKMRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT         3736 a         1752 c         1546 g         3571 t
ORIGIN      
        1 atactcttaa aataaaatta tataattaaa aatactctat aaaagctaaa aagtttttct
       61 attcgctaca tctaaaaata attagataga ggtataaatg tatttagttt atttatacct
      121 ctagtctttt ataaattata tctctactaa attgattttt tagcacgaat aagtgtgctc
      181 ttggagatac cagtcatctt cacaacctct ctatatggct tagaatttaa taaccccaat
      241 gcatattgta tctgttgatt gctgtatttc tttggcctac catctttaaa gtcctttttc
      301 tttttagcaa attcttttcc taattgagta cgttctatta tcatatttct ctcaagttct
      361 gcaactgcaa gtaatgtagt caaaaagaat ttacccattg aagtattttc taaaaggcct
      421 atatttaaaa tatgaacact tacttcttta gcaaataaac cttctattag ttgtattcct
      481 tctgatgtac ttctagctag tctatccagc ttagttgcaa caagtaagtc tccctttttt
      541 agagatgata taattttttc aaatttaggc ctgtttgtag tagtgcctgt ataagtttcc
      601 tttattattt tagcatcatt atatttattc aaaatttctt gctgttgctg atacaaactg
      661 ttgttgtctg tttgattttt tgtacttaca cggcaatatc catatataat aatcatcact
      721 tcctaacata aagattttgt acagaagtta cccagaagct tgtttttact tatctttatc
      781 cattttacta aaacgatttt tgggtgtcaa tactgttaac ttttgacacc ataataattc
      841 ctttataatt tgtttgacta tgtcaaaaat taccaatata atgaaattaa tgagtttata
      901 caaattggag gaaataatat gaatagtctg ttaaaagaag caatagatga attaaaaaac
      961 atccattgcg gggaagtttt tttattaaaa gaattgttca aaggctatga atggaacagg
     1021 ttggagatga atatcagatt gaaattagga aaactttttt tgtatgaagt ggtaactaat
     1081 cccaatttaa atgtagaggt catcaataaa aattctgctt atcagcaaat gtataaaaaa
     1141 aaatagtgac ttaaatgtat ataatagtat aatcttctta ttgattcaaa agttaaaact
     1201 tttaatacaa aacaatcatt ctattttaac atttatcaat atgtctaaat ttatataatt
     1261 aacacatacg aatagtattg tttaaatcac attatttaag atagataaat cttaacccta
     1321 ctccagcata aatactaaaa tagggcttag aattatctat atttttatcc cataaaatgc
     1381 ttagctcttc ctcttgattg aacatatata tctggggaaa tacaatagaa gcgtaaattt
     1441 ataaaatttc caaagtcaga aaacttcagt tcaaacttag gtataccaaa actttcaggt
     1501 gctatttcgt caacgccaaa atagatgata attccattat ctgtaagata aaatgcttgg
     1561 tcttcaggta taactaactc aacattagaa taatacattt ctctattttc atttatttga
     1621 gatttaatgt aatcagtaat tatattaata taatcaactc catctctaaa aatgtcatta
     1681 agtaaaagtt cttttccagt tgtcaaatct atattgtaat tattcaatgt attgtattta
     1741 ggcccatagt tattagcaaa ccccataagg tttaatatca tactcagtac ataattttta
     1801 ttaaaagtaa ctgcgtaact ggtagatacc caatagcttt gttttggaag tgaattttga
     1861 gaagctgcgt tattatattc tcgttcttct tcctgtaagc catttttaaa attatttaca
     1921 gtcattctta cagcattgtt tatgttattt aaaataactg ggtttacata cgtggattga
     1981 tttctaatat tgtatataac aggatacttt acatcatatg aaaaatactt acttctttca
     2041 aaatcttcat taaattgtac atataatata ttatatgtac aggtatttgt agattgataa
     2101 ttttccatta aaatcctccc ccttttataa aaaaatcaga tacaatataa tatgcttaaa
     2161 acagtaataa tgttaatggt aaatgtaaag aatagaaagt atctaaaaca gcaaaaaatg
     2221 actaattttg tggtataata cataggattg agagttattt tataggagga aaaatatgtt
     2281 attattagca gataaatgga aagattatga acttatagat atgggaaatg gagaaaaatt
     2341 agaacgttgg ggaagttatg tacttagaag accagaccca caggttgtat ggccaatgga
     2401 atctgaatgg gctttatgga aaaaccctca tggacattat cacagaagca ataaaggtgg
     2461 aggtcaatgg gaacacaaaa aaagatatcc agaacaatgg actataaatt ataaaaactt
     2521 aaagtttcac attaaaccaa ctggctttaa acatactgga ttattcccag agcaagcagc
     2581 taactgggat tggatgatag agaaaataaa gaaagctaac agacctataa aagtgttgaa
     2641 tctttttgca tatacaggtg gagctactgt agcatgtgca tctgctggtg cagaagtatg
     2701 tcatgttgat gctgcaaaag gtatggttaa ttgggcaaaa gaaaatatag aattatcagg
     2761 tcttaaaaat caaacagtaa gatttatagt ggatgatgtt gtaaagtttg ttgaaagaga
     2821 aataagaaga ggtaaaaaat atgatgcaat aataatggac cctccttctt atggaagagg
     2881 tcctaaagga gaagtatggc aaatagaaga aaagttatac agttttgtag atttatgtat
     2941 gggagtttta tcagataacc ctttattttt cttaattaat tcttatacaa caggattttc
     3001 tccaatagtt cttgaaaatg tattgtctac aacaataggt aaaaagacaa atacaggaga
     3061 tatatacggt ggggaattag gaataccagc ttccagagat ggtaagatac ttccttgtgg
     3121 tatatttgga agatgggaga aaaaataatg ataaaagtca tatatgaaga taaccattta
     3181 ttagttgtag aaaaaccagt taacatattg tctcaaggag ataatactaa tgataaagat
     3241 atggtaaatc ttttaaaaga ctatattaaa aaaaagtata acaaacctgg aaatgtatat
     3301 attggtttaa tacatagatt ggatagacca gtaggtggag ttatggtgtt tgcaaaaaca
     3361 tcaaaagcag catctagatt gtctgagcag gtaagaagta agactttcaa aaaaacttat
     3421 ctagctgttg ttcatggcaa gataaaatct aactcagata tactaaaaga ttttttatat
     3481 aaaaataaaa aaactaatat ggtaactgta gtgaaaaaaa gccataaaga tgccaaagaa
     3541 gctgaactta actataatgt attagatttt aaagaaaatc taagtttagt tcaagttaat
     3601 ttaaagactg gtcgttctca tcaaataaga gttcaatttg caagcagaaa acatccatta
     3661 tacggagacc aaagatatgg caaagaaata aataagattg gacaacaaat atctctttgg
     3721 tccaataaga tagaaatttg ccatcctact acaaaagaaa aaatggaatt tacatgtcat
     3781 ccacctgaca aatatccatg gaatatattt taaatctcaa atgaggtgat tatatgagta
     3841 aaaaattttc aataggagaa atgtctaaac ttcataaaat aagcatacag acactaaggt
     3901 actatgacca aatagattta tttaaacctg ttcatgttga ccaagaaagc aattacagat
     3961 attactcaat tgaccaattt tcacaattag atattataaa atatttaaaa tatttaggta
     4021 tgcctttaaa agaaattaag tcaaagcttg atgaaaataa tgaagaaatt ctaaaattac
     4081 taacaaataa aattaatata gtggatgaaa aaattaaaga attagagctt ataaagaagg
     4141 tactaagcac aaagaaagaa actatggaaa aaggtatgaa agtagatgaa gttggtaaaa
     4201 tagtgagaaa acatattcca cgaagaagta tcttatctat agagtatgaa gaaggattaa
     4261 gtagtgaaga aactatggaa ctttccagaa gacaaatagc aaatatatta gaagataata
     4321 tatctgtgtt ctatggtgga gtaagtggac ttgtatctat agataaattt ttaaaagaag
     4381 ataaagttat ttatgacaat agttttgtta ctgttgaaag agacttattt gatataaaat
     4441 cacaaaaaca tataacagaa atttcatctg gtgattttat ttgtatgaca tataaagggc
     4501 cttacaaaga aaattatacc gcttttaaga aactggttga ttatgttgaa tataaaagaa
     4561 tacctattga aaattatata tatgaaatac ctataataga ccctctgtct acaaacaacg
     4621 aagaggaact tctaacagaa attcaaatac aagttaaaaa gagagaaatt gacttaagat
     4681 gtctagtgta gtaatctagt ttacttacac atcttaatat agttgtctat tatcaacata
     4741 tgatttttct agatagtgat tcctaacagt gagattttca aaaaatagga ggaaatatgg
     4801 ctaatgctaa ttccctccta tttttaatta agccatatca ttttaattaa gccatgtcat
     4861 cacgaagtgc atcaataata ttttcttttt ttatcttatt aatagtatac aacattgtaa
     4921 taaatactat aaataaaaca ctaaatatac taattccaat actaaaccat ggaatcacaa
     4981 aatcaatatc atctgtaacc attactttat gaattagcca tgaagaaatt actgctatag
     5041 gaagtccaaa gaacaatgct ctcatgccat aaaaggcaca ctcaaaattc atcatctttt
     5101 ggaaatcatg ctcagacatt cctacagagc gaagcatggc aagttctcta cgacgtaact
     5161 taatattagt tgaaattgta ttaaacacat tggcaatcga aatcagagaa atcataatta
     5221 tgaaagtata agcaaaaaca ttggcaataa aaatgtaatt acggttctca tccatcattc
     5281 catacatatt gtacagattg tactcattcg taactccctc actctcaata atttgctcca
     5341 tttctgcaac tgactgagta ggatttttcg attgaaagct taaactttca attcctgtag
     5401 aaacaccagg aatctcaaac ttatctttgg ctgaataagg agccaatact ctgaagcttg
     5461 ctttcttcac atctgaactt ctgattcctg gaggagaatc aggtggcact actttgacaa
     5521 atgaaatatt cacattttgt ctctcaggta tctccaactt gccattagtt tcaggagtga
     5581 ggctaacatt catagaagaa ctgttgaaaa tatcaataat attattatcc tttgttacca
     5641 tagaaacagc aatcagtttt gcattttgtc cagtatattc ttctgctggt aatccaagac
     5701 ttttaataat attcagataa gttctatcat caagaaattg catatctact ggtaattcaa
     5761 gcatttcact catagaatgt gaaccctcat agttcaaata atcgtctgta agctcactta
     5821 ctttggcaac acatgaatag gtcataagtt tctgatacaa accttcgtaa acaccatttg
     5881 cagtttttag cttatcgtaa agcttcaaca tttcgttgtc tttcatacct tgtgtagaaa
     5941 aaataatatc ctggtcagta acctctgacc tctgatttga catctgtttt aggtctgcta
     6001 ctaaagcact tgtagatata aatagaacta tgcttaaaac aagcgacaat acaatacttc
     6061 gataacgttt cttgtttctt ttaaagtttt tcatagcaag aactccctca agaccataaa
     6121 ctcgctgtgt tagttttgat gtcttcacag atttagattc aatttttacc tcatttgtct
     6181 gacgaataca ctccatcact ggtgtgttgg cagcctttct tgctggtatg taagcagaaa
     6241 ttaagattgt aaccatactt accactgctg caacgatgat tgcagggata gacaatgtta
     6301 atgtcaacgg aacgtttaca tagagaatat ttgcaaagtt tttagatatg acagaaatca
     6361 caagtccaat actgactata ccgattgcaa caccaattgg tataccaatc gcaccaatgc
     6421 aaattccttc aaatagcacc gaatttcgta actgttttgc tgtagctcca acagatgaaa
     6481 gtattccaaa ttgatgtgtt cgctcgttca atgacatgtt aaatgaatta tatattagaa
     6541 aaattgagcc tagcatgatt atggcaagca caatgccacc aaccgagtac aaaaacatat
     6601 tgaacaaatt gttatcagag atacctatga atcgcaacac attgtcattg aaaatggaag
     6661 catggtcttt agtgctactt gtgtaagagc gaatctgatg tggatttttc aatgtgacaa
     6721 aaaggctaag actgtcagtc ttgacttgtt tatcttcttt ggttatcaag gtatatcctg
     6781 gtgcagaaga ttcttcaaat acgggctttc tacagatacc cacaactgta taagttttct
     6841 tatcctgtgg cacaaaaact tcactcccag cagtgtatgg gtcactctga ccaagctttt
     6901 cattttcact cattcgtttc cctacatcca aagaaatagt atcccctact gcaaatttga
     6961 caccaccatc tgtcgcaact ttacttgaaa caagaatctc tctactattt tcaggtaatc
     7021 ttccagaaat taaagttata ggcaaagtat caaaagcttc tttgctaaat ccagcaataa
     7081 aaagatatgg tttatctgga tttctgttac cttcaagtgt tgcatagcca atattttcaa
     7141 atgttgcagt atttgcaact tcatcattga ctctttgttc ctgtacaaaa gaagaatcca
     7201 catccaaaaa ctggacatgc caatcaccat attttataat agctccattt atcatatagt
     7261 tcatcaaaga aactccaaag gtagtaactg ctgtaatcat agcagctgac agaacaactc
     7321 ctataattgt tacaagagtt cgagttcgat tctttttcaa tccttgcaga gcaactttgt
     7381 taaaaatgtt cattaacgat tcaccttcct ctcatcacgc actacttttc catctgaaat
     7441 acagataatt ctatctgcct gtaaagcaat gttttcatca tgtgtgacaa taatgagagt
     7501 ttggtgatat ttactatggc tctctttcag taactggata atctcttgtc catttttact
     7561 gtctaagcta cctgtaggct catcagcaag cataactgct ggtgcattca tcaatgcacg
     7621 accaatggca acacgttgct gttggccacc agaaagttga tttggtaaat gtgtttttcg
     7681 ttcttttaaa ccaagtaatt ctaacaagtc atttaaccgt tcttgattga ccttacgctt
     7741 atccataagt ataggcaatg tgatattttc cactacattt aatgtgggta tcagattgtg
     7801 aaactgataa atcaatccaa cttgtcgcct acgaaaaata gcaagttttt cattgctttg
     7861 gccatataca tcttgcccct ccagatatat ctttccactt gttggtacgt ctactcctgc
     7921 aatggaatgt agtagtgtag atttaccaga accagaagaa ccaatgattg cagtaaactc
     7981 ccctttttca atagtaagtg agacatggtc aagtgcagta accttatttt cattcttacc
     8041 ataaacctta cataaatctt caatctttaa aaacgccatt atataagtct cctttcatat
     8101 tttataaata tatcatagaa ctttcaactt acatttaagt gacatttaaa tgagagattc
     8161 gtcactttgg aaaacgaata acaaatattg caccaccttg tgggtgattt tgtgcagtaa
     8221 ttgttcctcc ttgtctcata ataatcgtct tacaaagtgc caatcctatt ccataaccgg
     8281 ctgtgcttga atttttccca cgataaaatc tgttaaatag acatggtaaa tcttcttttt
     8341 taaagcctgc tccgttgtca tgaatagtaa gttgagtaaa caaaaagttg tcctcacaaa
     8401 tgatatcaat ttttccatta tcacccacac tctccatgca gtttttaaat atattttgaa
     8461 ttgcttctga aagccaattt aaatcaccca aaatccttac tccttttggt atatcaatat
     8521 gtaaagtgat attgtgcagt tccatgggaa tcaaaagttg atgaagtgca gaactaatca
     8581 aattattcac atcaatttgt tctttttgaa agactacaat acctgcatct aaacgtgata
     8641 attttaaaag ggaagtaatc agccagtcca ttcgtataag taattcctct gtttctcgta
     8701 tcaactcttt tctctcatct tcatcagaag tattctctaa cagtgacaaa ataagagtta
     8761 ctgatgtaag aggagtgcga agctggtggg ctatgtcagc tagtgagtca gcaaggtgtt
     8821 ctttttcttt tttcagtgcg taattttgct ctctaatgcg taacgtcatt ttagttattt
     8881 cactttgtag aatagaaagc tcaccctcat ctgattcagc aatatacaga tggttagcat
     8941 tatgaagcac aagattaatt tgttctgaaa tctgtgcaat acttttgtat cgatttttag
     9001 taaacacaaa aaatgctatt ccaaaggtag tggcagaaac aatagaaagt attccagtca
     9061 taatactgat tgcaaatccc agggctacag tgagaatagt aattaataag aataaaatag
     9121 caaattttcg aaactctcta tttcgaaaca taacttcccc ccaatctata ccctgtccca
     9181 cgaacagtca aaattatttg tggacttgaa gggtcatctt ctatcttctc tcgcaagcgt
     9241 ttgatgtaca cagtcaatgt gttgtcatta acaaactcac ctgccgcatc ccacaattca
     9301 tcaagtaatc ttaccctcgt aataatactt ttaggattgc taataaacac caataacaaa
     9361 cggtattcta aagctgaaag aaaaacctca ttgccattct ttttcacaac accagttgct
     9421 gtatctacat aaagcccaca aatttcaaaa gttgacccaa aacgcccact ttttcgtagt
     9481 gctgttctaa ttcgcgcaat cagttcacgt ggacgaaaag gtttagtaat ataatcatct
     9541 gcacccatat tcagtccagt aacaacactt gattcatcac cggaagctgt caaaaagata
     9601 acaggaatgt cttgcttttc tttgatttct gtgcaaatcg taaacccatt tccatcaggt
     9661 aaagaaatat caataagtgc caaatcaaat ttattcttag caatctctac aagtgcttca
     9721 cttcttgtgg atacatgggt tactataaat ccttctgaat taagcaaaag aataagattt
     9781 ttggcaattg ctttatcatc ctcaactaaa aatatccgtt tcatttactt tcatcctcct
     9841 ttattttatt agttttatat attccagcag agcaatagta cactactatt ttacttatca
     9901 ttacacaatt ttcagtagtt tcttttgttc ttatataatc catgcataat acctccattg
     9961 atttattata tttcttataa cataaataca caagataaga caaaaaacat aatgtaagtg
    10021 caagtttttt aactcactaa cttataaaca tacactccta ctaacactac tttcttgatg
    10081 acacatctta caagcttata ttcatacatc aatgaaaaat taaatttatc catttattaa
    10141 aataaaaggc aatagcttct atagctaatg ccctttatct taaaatgatt taaatactat
    10201 acaattttta taaatggcta taaataaact cgtatagaat ataaaattta tctacagtct
    10261 tttgttatac aaaatttata acctcttata gaacaaattt accactttgc aaacttatca
    10321 cttttactca gctatattat aaacttttaa tttatctttg tttaaatgtt tcttcttaac
    10381 ttctactaaa gcttttagcg tatccaaaga tgtcattatt tcagtagaaa attcaatggc
    10441 tgttcttctc atcttaaatc catctcttgt agagtcattt cctttagttg gtgtatttat
    10501 tactatatca acttgtttat ttcttatagc atctaatatg tttggtctag gttcttcaat
    10561 tctatttact atatcagcct ctattccatt ttctcttaaa ctctt
//
LOCUS       DAMJWC010000105        10419 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMJWC010000105 DAMJWC010000000
VERSION     DAMJWC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10419
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.110"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            173..1495
                     /locus_tag="PC503_003372"
     CDS             173..1495
                     /locus_tag="PC503_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2529326.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            1792..3153
                     /locus_tag="PC503_003373"
     CDS             1792..3153
                     /locus_tag="PC503_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2529327.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            3226..4620
                     /locus_tag="PC503_003374"
     CDS             3226..4620
                     /locus_tag="PC503_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2529328.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            4682..5152
                     /locus_tag="PC503_003375"
     CDS             4682..5152
                     /locus_tag="PC503_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF2529329.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            5155..7371
                     /locus_tag="PC503_003376"
     CDS             5155..7371
                     /locus_tag="PC503_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2529330.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            7454..8125
                     /locus_tag="PC503_003377"
     CDS             7454..8125
                     /locus_tag="PC503_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2529331.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            8488..9702
                     /gene="dpaL"
                     /locus_tag="PC503_003378"
     CDS             8488..9702
                     /gene="dpaL"
                     /locus_tag="PC503_003378"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2529332.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            9829..>10419
                     /locus_tag="PC503_003379"
     CDS             9829..>10419
                     /locus_tag="PC503_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2529333.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         3891 a         1218 c         2149 g         3161 t
ORIGIN      
        1 taaaaattat atatgtaaaa caattatgtt aaaaaattgg cattataatt gcttcatatt
       61 aagttgagat gacaaaataa aaaaagaaag gatgttgtgt gagataataa taactgtcat
      121 taaaaaatag ttgggagtga taaccttgag taaatatcaa aagaatgttt ctatgtttga
      181 tattgatgga aggccaccaa ttttaaagtg tttgccacta tcaatgcaac atatactagc
      241 aatgatagtt ggaactgtta cagtacctat agtcgtagga ggagctgtgg gtgttagccc
      301 tacacaaata acacttttag tgcaatatgc attaataata gctggtatat caacacttat
      361 acaactatat ccaataggaa atattggttc aagattgcct ataatttttg gagttggttt
      421 tacttatgta ccaacacttg tagcagtcgg aggaaattat ggattagcaa gcattttggg
      481 tgcacaatta atagggggag tggctacagt attaataggg atattcataa aaaagataag
      541 aaaatttttt ccgaatatag ttgcaggaac agtggttttt acaattggat tatctttgta
      601 tcctatagca ataaattata tggcaggtgg tgtaaatagt cctacttatg cctctatgca
      661 aaactgggca gtagcggcta taacattagt ggtagttata ggtcttagtc aatttgcaaa
      721 aggatatgca aaattggcag caatattttt gggaattata gttggatatt gtgtatcttt
      781 agttctgggt ataataaatt ttgaccctat tagagaggca acttggtttg cgatacctaa
      841 accgcttgaa tttgggatgg aatttgatat gcctgtaata atctcagtag taattgtaag
      901 tataatcaat gctgttcaag caattggaga tttatcagct actacaatgg gaggcatgga
      961 taggaatatc acagataagg aattatcaag tggagtaata ggaagtggaa tttgtactat
     1021 gataggagct ttgtttggag gtttaccacc atcatcatat agccaaaacg tggggatggt
     1081 agctatgaac aaagtaataa gtagatttgt gcttggaata gctggtatat ttatgttatt
     1141 gtcggggttt gtgcctaaat ttggtgcact aatgactact ataccatatt ctgttttagg
     1201 aggagctaca atatctatat ttagtatgat aacaatgaca ggtataaagt taattattac
     1261 agaagagttg tcatcaagaa atattaccat tgttggtttg gcaattgcct taggcatggg
     1321 aataacatca gtaccagcag cccaagaggc atttccttca tttgtaaagt tagtatttgg
     1381 agaatctcca atagtaattg caacattggt tgcattcgtt ttaaatctaa taataccaaa
     1441 taaaagtcta gaggatgagg ctaaagaaag agctgttatg gaagagacta attaagatat
     1501 aataatttaa aagaattgtt taaattattt agtatgagat tgttagatta tttttgatag
     1561 ctattcattt taataaaaaa tttaacaaat aaatatatac caggcaatta atgttcattt
     1621 aagttgaaaa tcggggaggg aatatttaga aatttgttaa ttttttataa aaatagctca
     1681 gtttagctgt gtttatcggt tgagcaataa attcatggtc ataaaaatat ttatagaaaa
     1741 taattataaa aatatttagt caagatattt atgtatggga ggatttattt tatgaaaaca
     1801 cgtaatactt caaaatatga tgtcgatggg ataccaccac taaaggaatc aatacctttg
     1861 gccttacaac atctgttagc aatgatagta ggaaatatgg tacctgcgat attaatagca
     1921 aacgtggtag gacttaacca ggggcaagca acaatgttga ttcagggttc tatgttagca
     1981 gcaggtttag caacgttttt acagttatat ccaatacctt tatttaaagg atttaagtta
     2041 ggttcaagat tacctgtaat gatgggaatg agttatgtat ttttaggagc ttgtctttca
     2101 gtagcagcta aagatggttt agcagctcta tttggagcac agattgctgc tggggtaatc
     2161 gtattctttg taggatttgg agttaagaaa attagacata tattcactcc aatagtttct
     2221 ggaactataa tagcatgtat gggacttgga ctattcgcaa cagctataaa gaatttagct
     2281 ggaggagaag gcacacaaac atttggaagc ccaataaact tcacagtagg agttatagtt
     2341 gcttttgtaa taataatgat aaataaatac ggtaaaggtt tagtaaaaaa ttcttcaata
     2401 ttaataggaa tattagtagg ttatgctata tctttagttt taggattggt tgatttctca
     2461 gccgttcaag gagcagctat agtatcttta ccaacaccag cagcttttgg attagaattt
     2521 agaccagagt taatagtaat gtttactatt atttacataa taggtatagc tgatatgatg
     2581 ggtgcctgta caatagctac agtaggagca atggatagag aggtaactga cgaagaatta
     2641 gcatcagttg ttttaggaaa ttctataact tctataattt catcactatt tgcagctctt
     2701 ccaactggag tatttagcca aaatacagta attgtatcta tgaacaaagt tacaagtaga
     2761 tttgtaatag cactaggggc acttgtatta ttactagcag ggatatctcc agcattgggt
     2821 gcaataatga caactatacc atcttgtgtt gttggtggag caactttagt agttttctca
     2881 tcaatagcaa tgtctggttt ctctattatg agtatggatg gattcactga agaaaacaat
     2941 cttatagcag gtgtatctat agcaacaagt atgggtctta caactgctcc acaagtttta
     3001 gaccaattcc cagaaacaat tggaactgtc cttggagggt caagtatagt ttctggagca
     3061 ataatagcta tattacttca aacattattt aaattaaagt cacgtaaaag tgctgaaaac
     3121 gttacttcaa atcttgagga aaatattgga taaatgtatt agatataata tgagaaaacc
     3181 atatggtaaa atgttgtaat gaaagtattc aaagggggat ttaagatgat tgatatacta
     3241 ataaaaaatg caataattgt tacagttaat aaagacagag atgttatatt tgatggagca
     3301 atagctattc aaggtgacag aatcttggac ataggaaata cagttgatat tgagcctaag
     3361 tatcttgatg ctaaaaaagt tatagatgct aatggaaaag taatattccc tggctttata
     3421 aatactcata atcacctgtt ccaagtgtta ttaaaaggtt taggtgatga tatggcactt
     3481 catgagtggt taaatacaat gatgtttcca tcagcaaaat tcttaacaga acaagatact
     3541 tatgatgctg caatgcttgg atgtatggaa ggtttaaaaa gtggtataac tacaatggtt
     3601 gattatatgc atactcacaa tagaccagga cttacagatg gaatagtaaa ggcatataaa
     3661 gatttaggta taagaggggt tgtaggtaga ggttgtatag atttaggtat tcacaaagag
     3721 cttatagaag atgtggaaac ggttgaaaaa gatttgagaa gggtattcga aaaatatcat
     3781 aattcagaaa atggaagaat aaaaatctgt gtagctcctt cttcaatgtg ggctatatct
     3841 gaagaaatgg gtaagatgct ttggaatata gttaaagaat atgattcata ttttacagtt
     3901 catatatctg aaacagaatt tgcaagaaca gcaacaaagg atatacatgg agaaatagat
     3961 ataaaattac ttgaaaaatg gggtatagta ggtccagaag ttgtagcagt acattgtgta
     4021 tgtataactg atgaagacat ggaaatgctt aaaaagtatg acataaaagt ttctcataat
     4081 gtagcaagta acatgtatct tgcttctggt gttgcacctg tgccagaaat gttaaaaaaa
     4141 ggtataaatg tgagtttagg tcttgacggt gcagcaagta ataacgcaca agatatggta
     4201 gagcttatga aattaacagc tttacaacac aaagtaaata attgtgaccc tctggcaatt
     4261 tctgcagaga aagttcttga aatggctaca attgagggag caagaactct tagaatggaa
     4321 gatgaaatag gttctttgga gattgggaaa aaagctgacc tagtaatatt taactcaatg
     4381 ctttctccaa aatcaatacc tcttcacaat cctgtatcaa ctttggtata ctcagctagt
     4441 atgcacaatg tagagagtgt tttagttgat ggaaatgtaa tacttgaaaa tggaaaagta
     4501 actacaattg aaagtgaaga acaagtgttg cttaatgcac aacatgcagc agaagaatta
     4561 tgtaagagag ctaatgtaac taatagaatg gaaggacata agtggaatag cttatactaa
     4621 tattaaaata agattgtaat aatattctat tacaacatta gtttatctgt aggaggagaa
     4681 aatggaaaaa ataaaattaa atattaatga ttacatgtat gaaatagaag ttgaaaagaa
     4741 tgaaactctt ttgcatgtac ttcgtgaaaa attaaatcta actggagcga aacaaggttg
     4801 taatagtggc agttgtggag catgtaaagt tttgatagat ggagttgaca tgaaatcttg
     4861 taaacttctt gcaaaaaact gcgaaggtaa agttatatac actatagaaa gttttgctaa
     4921 tggagaaaat cttcatccaa tacaagaagc ttttatagaa gtcggagctg tacaatgtgg
     4981 atattgtact cctggtatga ttataacaac acaagctctt ttaaatagaa atgcatctcc
     5041 taatgaagat gaaattagag aagcttttaa agaaaatctc tgtagatgca caggatatgt
     5101 aaagattata gaagctgtaa aattatctgc agctagatta gggggtagat aattatggaa
     5161 aaggtaatag gaaaatcata ccctctaaaa gatgcagctt taaaagttac tggtcaaatg
     5221 aaatacgtgg ctgatatgaa accacaaaat gtactttacg ctaagatgct tttaagccct
     5281 gtagcacatg caaaaataaa aagtatagat acaagtgaag ctgagaaagt agtaggtgtt
     5341 agagctatag ctacttatct caatacatca caaagaaaat acaatggttc attaagattt
     5401 tatgagcaca aaatacctga aaatgaagtt atattttcag atacagttag atttgttggt
     5461 gaccgtgttg cagcagtagc tgcagagact ccagaaatag cagagaaagc tgtaaaactt
     5521 ataaaagttg aatatgaaga attgccagct gtatttacta tacaagatgc aataaaagaa
     5581 gatgctatct gcatacatgg agattcaaat atagtttctc aaaacaacat aaatggggga
     5641 gatgtagaaa aaggcttcaa ggaatgtgat tatatatttg aagatgaata ctctactcca
     5701 gcaatacatc atagtgcaat agagactcat agtgtaattg cacactatga ttataatgat
     5761 aaattaactg tacatacacc ttgccaaaat acatttggat ttagaataat actatctcaa
     5821 atttttggga tgtcattaaa taaagtaaga gttataagac ctgctattgg aggctcattt
     5881 ggtggaaaat tagaacttac aattgaacca gtagcagccg cattatcaaa aatgacaaga
     5941 agaccagtta aaatggttct tacaagaaag gaatctatga tatcaacaag aactcgtcat
     6001 gggtcttttg taaaattaaa aactggtgta aataaagatg gtgaagtaat agcacaagac
     6061 ataaaaatat atacaaatac aggagcatat gcatcaagtg ctttaaatgt tataggagca
     6121 cttagtcata aagtatttaa agtttataaa ataccaaata taaagtttac tgggatgcct
     6181 gtatatacaa atacaccaat agcaggagct atgagaggct atgggtcacc tcaaatattt
     6241 atggctcaac aagctcaatt tgcgaaaata gcaaaggaaa taggtatgga tttagtcgat
     6301 tttcaaaata aaaatgcagt agagccagat gatgtcgata taatcttcca cggttctctt
     6361 ggaaatccta gagtattgga ttgtatagag caaggtaaga agatgtttaa gtgggatgaa
     6421 aagaaaaaac ttccaaaaga agaaggaaaa tatttaagag gtataggtat ggcaataggt
     6481 gcacatggta atggagtttt tggtgcacat agagatgttg ttacattgac tcttaaatta
     6541 aatgaagatg gtacgttgac actactaaca ggagctcatg atatgggtaa tggtgttgta
     6601 actatgcaaa caatgatggt agctgaagtt ttaggaataa cacctgataa agttgataca
     6661 tttgaaactg atacggatgc atgtacattc aaccttggtg actatgcaag tagaggggta
     6721 tttgtagaag gtggaggagc taaaaagaca gcagagaaat tgaaaaatct tatattagaa
     6781 gaagcagaaa aattacttga aacatcaaaa gaagatttat atctagacaa tggatgtgta
     6841 attagtaaac ttgatgaaaa tgtaaaagca tcactttctg atgtcgcagt atatagtcaa
     6901 agtaaatcat taagagagtt aactgttgtt gaagattatt cttcaccagc tggacgtact
     6961 tcttatggtg tacattttgc tgaagtttta gtagataaag aaactaagga tataaaagta
     7021 gttgattttg tagctgtaca tgatgttggt agagttataa atcctctaaa tttagaagga
     7081 caattagaag gtgggattca tatgggtcta ggatacgcat tgagtgaaga attggcattt
     7141 gatgaacaag gtagacctaa agctactgat tttaaaacat ataaattatt tagaactgta
     7201 gatatgccaa aatgtcaagt tgcatttgta gatggttatg aaaaagctgg gccttttggt
     7261 ggtaagagta ttggagaatg tgccgttgta ccagttgcgc cagctgttgc aaatgcagta
     7321 tataatgcaa ctgatgtaga gatacattca ttaccaataa aattaaaata gtagaaatta
     7381 aagcagaaat aacaatttat tgtatttgta aatagataat aaaaatagat ttatttggtg
     7441 aggagatatt attatggcaa agatattagg tatttgtgga agtccacgta aaggagcaac
     7501 agaatatgca gtgttagaag ctttgaaaga agcagaaact atacctggta tagaaactga
     7561 gtattggtca gttagaggga aaaaaataag tccttgtgta cattgtgatg catgtataag
     7621 aaaagaaact atgtgtatta taaaagatga tatccaagaa ttagagcaaa aaatattgga
     7681 ggcagatgga attatagtag gttctccagt ttatgatatg aatataactg ctcaacttac
     7741 agcagtattt aatagacttc gtccaatgta tttagttcat ccaggaaaac ttcaaaataa
     7801 ggttggtgca gctataacta ctggtggaac tagatatggt ggccaagaat tgacaaaact
     7861 tcctataata aatttcttcc taatgcatga aatgttagtg tctggaggtt taggtggatg
     7921 ctatataggt ggtacaatat ggagtaaaga tggaaaagca aaaggtgccc aagaggatga
     7981 gacaggtatg gacacagtaa aaagacttgg aaaaggtgca gcagaggcag ttatggtttc
     8041 taagtttggt cttgaaaaat ggaatgtcgt aaaagaagaa ttagatgtta aaaaagatga
     8101 aaaatcacct cttagagacc actaaagatt tattatatta ttgaatatat acaaatagtg
     8161 atgtaataga ttattgcatc actattttat gttttaattt agattttata aattttatat
     8221 taaaaaatat agaaacaaag tgttttgaga tttattttta aattttaaaa atgagaatta
     8281 aaaagtgaga agatagaaaa ggttttttag ttattaaatt ctacatacat tgtatgaact
     8341 aaagatagaa aagaaaaaat aataaaagca ttgcaatttc tatactaaag agtcatggaa
     8401 aaatatctag tatatattta gtattggcat gttaattgct tatatattaa agtataaaaa
     8461 tttaacaata atttggaggt attttagatg ttaaaagaaa ttaaatggaa agtaaataat
     8521 ttgccaaagg gcgataagga aaattgtatc aaatttttaa atgaagaaga aataactaag
     8581 gttagaaatt ttcacaaaag ctttcctcaa tataaagaaa ctccattagc aaacctagaa
     8641 ggtttagcaa aaaaattagg tgttgcagga gtatatgtaa aagatgaatc ttatagattt
     8701 ggattaaatg catttaaagt attaggtggt tcttattcta tgggtagata cttagctcaa
     8761 agattagata cagatatatc tgagttaggg tatgacaaat tgacttcgaa agaaataaaa
     8821 gaaaaattag gagaaataac tttctttaca gctacagatg gaaatcacgg tagaggagtt
     8881 gcttggacag ctaataaatt aggtcaaaaa tctgttgtat taatgccaaa aggttcttct
     8941 gaatttagat taaataaaat taaaggagaa ggtgcagatg ctagtataac agacttaaat
     9001 tatgatgatg cagtaagatt agctaatgat tatgcagaag ctgatgacca tggagtaatg
     9061 gttcaagata cagcatggga cggatatgaa gaaataccag catggataat gcaaggatat
     9121 ggaactatgg ctcaagaagc tatagagcaa ttaaaagaat atggagtaga tagaccaaca
     9181 cacgtatttg ttcaagcagg agttggttca cttgctggtg cagttcaagg gtatgttgct
     9241 tcaatatatg atgaatgccc aataacagta gtagtagagg ctgatgaagc tgattgttac
     9301 tataaatcag cagaagctgg agatggaaaa ccaagatttg ttggaggaga tatgccaact
     9361 ataatggcag ggcttgcttg tggagagcca aatactatag gatttgaagt attaaaaaat
     9421 catgcagcag catttgtttc agcaccagac tgggtttctg ctaaaggtat gagaacatta
     9481 ggtaatcctt taaatggtga tgaaaaggta atttctggag aatctggagc agttacaact
     9541 ggtcttttag tagcagctat ggaaagagaa gatttagcag atttaagaaa agatttaaaa
     9601 ttagatgaaa attcaagaat acttttaata agcacagaag gagatactga ccctgacaaa
     9661 tatagaagta tagtttggga tggagaatat ccaagtatat aaggaattac taaaatgcaa
     9721 ttattagata ttggtttaca tatttagaag atatataagt tctaaaattt agaaaatata
     9781 taagtatata aaatacatac attataaaaa atctaggggg ataatgaaat gttaaacgaa
     9841 caaagaaaac aagaagtaac tgaaatatgc caaaaattaa ttcaaaatcc tagttcttct
     9901 ggaaatgaag aaggtgttgt aaaagcaata gaagagtctt ttgaaaaatt aggttttgat
     9961 agttggtcaa gagatagata tggaaatata gtaggatgta taaaaggtaa caagccaggt
    10021 aagaaaatat tatttgatgg acatatagat acagttccag ttccagatgc aagtaaatgg
    10081 agtgttcctc cttttgaagg aaaaatagtt gatggaaaga tatatggtag aggaacttct
    10141 gacatgaaag gtcaatatac tgcaatgatg tctgctgtag cgtattttgc taaagacact
    10201 aatagagatt ttgctggaga actatatgta gcaggtgttg ttcatgaaga aatatttgaa
    10261 ggtgtttcgg ctagagagat aagtaaggct gttcaacctg actatgttgt aataggtgag
    10321 tcttcagagt taaacttaaa gattggtcag agaggtagag gagaaatagt agtagaaact
    10381 tttggtaaac cagctcactc tgctaatcca gaaaaaggt
//
LOCUS       DAMJWC010000106        10211 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMJWC010000106 DAMJWC010000000
VERSION     DAMJWC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10211
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.111"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            384..1544
                     /locus_tag="PC503_003380"
     CDS             384..1544
                     /locus_tag="PC503_003380"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF2529334.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            1546..2676
                     /gene="glgD"
                     /locus_tag="PC503_003381"
     CDS             1546..2676
                     /gene="glgD"
                     /locus_tag="PC503_003381"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF2529335.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            2705..4147
                     /gene="glgA"
                     /locus_tag="PC503_003382"
     CDS             2705..4147
                     /gene="glgA"
                     /locus_tag="PC503_003382"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF2529336.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            4161..6581
                     /locus_tag="PC503_003383"
     CDS             4161..6581
                     /locus_tag="PC503_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF2529337.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRVLL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            6586..8451
                     /locus_tag="PC503_003384"
     CDS             6586..8451
                     /locus_tag="PC503_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HDF2529338.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIRIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            8696..9349
                     /locus_tag="PC503_003385"
     CDS             8696..9349
                     /locus_tag="PC503_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2529339.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            9445..10044
                     /locus_tag="PC503_003386"
     CDS             9445..10044
                     /locus_tag="PC503_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HDF2529340.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKDIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
BASE COUNT         4092 a          998 c         1864 g         3257 t
ORIGIN      
        1 acttgatttt ccttggataa ttatttaaca aatattagat tatattttgc tattacgaat
       61 ttaacaaatt aaaaaataag catgttcata tgacacaaag gatttataaa aaatgttttt
      121 atatttataa aataaaattt gtattatttt ttaaccgata attgaatatt aataaatact
      181 atagtgctta tggaaaataa tgtatacgtc ggtaagtcca ttatggggta tacattatat
      241 caattgtata gttgatatta ttttattttt attaaggtat tatttaagca acatttatac
      301 acgacattta ttgactgata aagtttataa aagtaaaaat gcaattataa atattaatta
      361 ctagatgagg ggagtgtcat taaatgaaaa aagagatgtt agctatgatt ttggcaggag
      421 ggcaaggttc aagattaggt gtttttacaa aaagaattgc caaaccagct gtatcatttg
      481 gaggtaagta tagaattata gattttgtgt taagcaattg ttcaaactct ggtattgata
      541 ctgtaggtgt tttaactcaa tatagaccgt tgatattaaa ttcacatata ggcatgggaa
      601 gtcattggga tttggacaga ataaatggtg gtgtctatgt tttacaacca tttatgaatg
      661 aaaaagaagg aaattggtat aatggtacag cacatgcgat atatcaaaat atggactttg
      721 tagataccta taatccagaa tatgtattga tattatctgg tgaccatata tacaagatgg
      781 attatagcaa aatgttaaaa tttcataagg aaaaaggctc taaagctaca atagcagtga
      841 ttgaagttcc ttgggatgaa gcttcaagat ttgggataat gaatacaaat gaagattcaa
      901 gtatctatga atttgaagaa aaaccaagtg aacctaagag caatttggca tctatgggag
      961 tatacatatt tgattggaaa atgttgagaa attattttaa ggaagcagaa aaaaatccag
     1021 aaataaatta tgatgatttt ggaaaaaatt taatacctaa aatgttagaa gataatgttg
     1081 gaatgtatgc ttatccattt aaaggatact ggagagatgt aggaactata caaagtctat
     1141 gggatgctaa tatggatata ataaaatctc cagaaacact tgatttagca gaccctaagt
     1201 ggaagatata tacaaatact atggcaatgc ctccacaata tataggtaaa aatgcaaatg
     1261 ttcatagatc aatgatagct gatggttgta gaattttagg tgaagtaggt aactctgtat
     1321 tatcacatgg agttgttgtt ggtaaaggaa gtaaagtaat tgattcagta ataatgccaa
     1381 atgttgtaat aggtgaaaat gtaactatag aaaaagctat gataggtgag tgtgcaacta
     1441 taaatgataa tgttcagata aagaatgtaa ataatgaaat aaatgtagtt tctgagtatg
     1501 aaaatatcga acctagatgc gtattaatag aaggaggtct ttaagatgag aaatgaatgt
     1561 ttagggataa taaatttaaa caaaaaagga gacccagcaa taaacaaact taactatgga
     1621 agaccaatag catctacacc aatagctgga agatatagaa taatagactt tgctttatct
     1681 aatatgataa attcaggaat cactaaagtt ggaatattcg caaaagaaaa atacagatca
     1741 ttaacagacc atataggtag tggtaaagat tgggatttaa gtagaaaaaa aggtggccta
     1801 tcaattttta gtccagaaaa cactaagtat agaaatactt actcacatag agaaggtgat
     1861 atatatacta tcttagctaa tctagattat atagaaaaga gtgaagaaga atatatttta
     1921 atagctccaa gctatatgct atgcaattta aattattctc aagcattgga ataccataaa
     1981 aaatctcata atgatataac tataatatat aaaaatgtaa ataatgcaaa taaagatttt
     2041 gctggtaact taactctaaa tttagatagt aacaataggg taataaatgt aggaaataat
     2101 ttaggtaagt tccctagagc aaacatatgt atggagacat atattatgaa gcgtgaagat
     2161 tttgttgaat gtatatataa cattgtaaat aaaggcaatt attgttattt agaagaattt
     2221 attattgaag aagcagaaaa catgaaaata ggagcctatg aatatacagg atatctaaaa
     2281 tgtgtaaatt ctgttgaatc atattttgaa atgagcaaag atttattaaa tttagaagtt
     2341 gcagatgaat tattatattc tgaaagaaag atatttacaa aagaaaagaa tgaatcacct
     2401 acaatttata cagatagtgc taaagtagaa aatagcttta tagcatctgg ttgtttaata
     2461 gaaggtactg taaaagatag tatcatattt agaaaggtaa atgttgaaaa aggaacagtt
     2521 atagagaact caatagtaat gcaaaattgt gtaataaagt caaatgcaaa actatataat
     2581 gcaatattag ataaaaatac aagtgtatca aatgggaaag aattaagagg agatgaaaaa
     2641 tatcctcttg tagtggaaaa gaatacaaat atataaataa attttttaga agggggaatg
     2701 actaatgaag gttttttatg taacagcaga gtgttggccc tttgcaaaaa ctggaggatt
     2761 aggagatgtt tcttatgcat tgcctaaaga attaaaaaaa gaaggtgtag atgtaagggt
     2821 aataatgccc aaatattcaa ctataccaag ttatttaaaa gatcaactaa aagaaatagc
     2881 tgtgtttagt gtacgtgttg gatggagaaa tcaatactgt ggtcttttag aaatggaatt
     2941 ggatggtgta aaattttact ttatagataa tgaattttat tttagaagag aagatgaaag
     3001 aaagagtatc tatggatatg gagatgatgc agaaagatat actttcttta cagatgcagt
     3061 tttagaagct ataagtagaa ttgattttta tccagatgta atacatataa atgattggca
     3121 tacagggatg ttaccattaa ttctaaaaga aagatatgca acccttgagg ggtataaaaa
     3181 tataaaaact atgtatacta tacataatct ccaatatcaa ggtgtatttg ataagcatgt
     3241 tttatatgat atattggact taccacaaaa atactttgat aatggagata tagagtatta
     3301 tggctcaata aattttatga aagctggtat aaattttgca gataaaatta taactgttag
     3361 tcctacttat gcaaatgaaa tacaaacatc tttttatggc gaacaattag atggattact
     3421 tagaaaagag tcaggaaaat taaaaggtat attaaatggt atagattatg atttaaatga
     3481 ccctgcaaaa gataaagata tatttgttca ttatgatgta gactcaattg acaaaaaagt
     3541 agaaaataaa ttgagattac aagatatatt gggactaaaa aaagattcat ctattccgtt
     3601 gataggtata gtttcgagat tagtttctca aaaaggattt gatttaatag catacatgat
     3661 gccagaactt atgagagaag atttacagat tgtcgtttta ggaactggag aacatcaata
     3721 tcaatcaatg ttcaactatt acgattctaa tttttcagat aaagtatcag ctagaattac
     3781 ttttaatgca tcattggctc aacagatata tgctgcaagt gatatgttct taatgccatc
     3841 attatttgag ccttgtggta taggtcaaat gttagctatg agatatggtt ctttaccaat
     3901 agttagagag actggagggc ttagagatac agtaacacct tataataaat ttactggaga
     3961 aggcaatgga tttagtttta aaaattacaa tgctcatgag atgtttttct gtttgaaaaa
     4021 tgcaatcaaa gtatttaagg acaaagaaaa atggattaaa ttagttgaaa atgcaatgaa
     4081 aacagataat agttggaaaa aatcagctaa ggagtatata gaaacatata gagacatatg
     4141 tgattaaagg agtggttttt ttggtaacaa taagcaaaaa gaaattcaag caaaaatttg
     4201 aagtaaaaat gtatagctta tatgcacaat ctatcaagga agctactgat gaacaattgt
     4261 taaatgtatt atgtagtcta ttgaaagatg agatagcaaa aaaatgggtt gctacaaagt
     4321 tagataagaa aaaagaagtt tattatttta gtttagaatt tttaataggg agacagttaa
     4381 aatctaattt attaaattta aatattgaag aagaagttag agaaggttta tctgaattag
     4441 gaatcaactt ggatgattta attgaagctg aagtagaccc agccttagga aatggtggac
     4501 ttggtagatt agcagcttgc tttttagatt ctatggcatc tttgaacata agtggtcaag
     4561 gatatggaat aaggtataaa tatggtctgt ttgaacaaaa atttgtaaat ggttatcagg
     4621 tagaagtgcc tgataactgg cttacagaag gacgatatgc atgggaaact gtaagaccaa
     4681 atgaagcaac aatggtgaag tttggtggtg aggtagaatt aatcaaggaa ggtagtcatt
     4741 taaaagtaat tcataaaaac taccttcctg taatggcaat gccttatgat ataccaataa
     4801 tcggatacca aaaccaatgt ataaatactt taagattgtt taagagtgaa ataccaaaga
     4861 gagattttgg tgaacttacc tcaaatgctc taaattattc tggtagctat gaagaggctt
     4921 taaaacataa gtattatact gaggaaatat cacaggtatt atatcctgat gattcaaact
     4981 atgcaggtaa gttgttgagg ttgaaacaag aatacttttt tgtaagtgca gggatacaag
     5041 atataataag aaaatataaa aagaacaaat taaatattaa taatttattc gataaggtag
     5101 caattcatat aaatgataca catcctacct tatgcatacc agaacttatg agagttttgc
     5161 ttgatgaaga aaatttatct tgggatgaag catgggaaat aactaaaaaa acagtgtcct
     5221 atactaatca tactataatg tcagaagcaa tggaaaaatg gcctgtaagt atgatgaaag
     5281 aactattacc aagaatttat atgataatag aagaaataaa tagaagatat gtagaggaat
     5341 taaataataa aggatatgac caagatagaa taaaaagaat gagtataata gactgtgaca
     5401 atatcaatat ggcaaactta tgtattgtca caagtcatag tgtaaatgga gttgctaagc
     5461 ttcatactca tattcttgaa acagaggtat taaaagattt ctatcaagat gaaccaaata
     5521 aatttaataa taagactaat ggaattgcac ataggcgatg gcttataagt tcaaatcctc
     5581 aacttagcaa tttaattaca gatttaattg gtgattcatg gaagaaagat acattacaat
     5641 taaaaaatat tgaaaaattt aaaaatgatt cctctgtttt acaaagactt gatgatataa
     5701 aatacaataa taaagcaaat ctagcaaagt ttataaaaga taaatacgat ttaaatgtag
     5761 acccaagttc gatatttgat gttcaagtta agagattgca tgcgtataaa agacagttac
     5821 tgaatatatt taatgtactt catatgtatc atgaattact tgataatcct aatttgaatc
     5881 ttgacccaag aacttttata tttggcgcaa aagcagcacc aggatattat ttggctaaat
     5941 gtataattaa atttataaat tctgttgcaa gtactataaa taatgatgtt agagtaaagg
     6001 acaagttaaa agtagtattt ttagagaatt atggagtatc attagcagaa ataataatac
     6061 cagcagcaaa tgttagtgag caaatttcaa ctacaactaa ggaagcatct ggaacaagta
     6121 atatgaagtt tatgatgaat ggtgctataa ctttggctac acttgacggt gcaaatgtag
     6181 agatatgtga acaggttggt aaagaaaata tgtttttatt tggacttagt gcagaacaag
     6241 tactaaatta taataaatat ggtggatatt cttcacttga cctatatcat tctaatatgg
     6301 atataaaaag ggtagtagat gatttaataa atggatttat tcctaatctt ggcgaagaag
     6361 gaagaagtat ttataattca ctcactactt acaatgatga gtattttgta ttgagagatt
     6421 ttgaaaatta tggtcaagct caagcagata taaacaggtt atatagagat aaagaaaaat
     6481 ggaataaaat gtctttagtt aatatagcta attctggatt tttttcttct gatagaacaa
     6541 tttctgagta tgcaaaagac atttggttta aaagggtgtg attaaatgca aagtgtaata
     6601 gaatataact cttgggataa aaattttaag gctccgtttg gagctttaaa atttgatgag
     6661 gaattgacca tttgtgttaa agtaaatgag ggatacaata tcaagtctat ttccctagaa
     6721 ataaatagag aagaagaaat gagaacaata actttaaatg aagaattaga taatgataaa
     6781 cttggaaagt gcttttgtgg taagattgaa aagtttgatg gtacaggtgt ttatttttat
     6841 tactttaaag ttgatgttga aatggatggt cagataaaga ctttatttta tggaaaaaac
     6901 agagataatg gatattcttg tgaatataat tatagtgata ttaataaata tcaaatcact
     6961 gtttacaaag attttaaagt accaacatgg tacaaagaag gaatacttta tcatatattt
     7021 gtagatagat tcaataatgg aaatcgtagt ggtaaggttg ataatcctaa aaaaaatagt
     7081 ttcatatatg gaaattggga agatacacct atgtacataa aggatagtca aggggatgtt
     7141 ataagatggg atttccatgg tggaaattta agagggataa tcaataaact tggatattta
     7201 aaaaaattag gtgtaagtat actatatcta agccctatat ttgaagcctc tagtaatcat
     7261 aagtatgata caggtgacta taaaaaaatt gacccaatgt ttggggatga agatacattt
     7321 aaagaactta ttgataaagc aaaagaaaaa ggtatatcaa tagtattaga tggagttttt
     7381 agtcatactg gagcagatag taaatatttt aatatgtatg gaaactataa tagtttaggg
     7441 gcatatcaat ctaaagaatc tccatattat tcatggtata tgtttgaaga atttcctcaa
     7501 aaatataaaa gttggtggga tgttaagaca ttgccaaata taaatgaatt agaacatagc
     7561 tatatggatt atataatata tgacaatgat agcgttataa ataaatgggt aaatatgggt
     7621 attaagggct ggagactaga tgttgcagac gaattaccaa ctaagtttat aagagagtta
     7681 aaaaaggaat taaaaaaggc agatgatgac tcaattctta taggtgaagt atgggaagat
     7741 gcatcaaata agattagcta tggtcagaga agaagttatt tattaggtga agaattagat
     7801 tctgttatgg gttatccttt tagaaataac atgttttctt tcttaaaagg agaaattaat
     7861 tcatatgaac tttgtaatag atatatgcag attaaagaaa attatccaaa agaatcattt
     7921 aggtctaatt taaatttaat tggaacacat gatgttacaa gagctaaaac ggaattaaat
     7981 gatgatgtag atttagtgaa gcttgctgta gctatacaga tgacatttga aggagtacca
     8041 tatatatatt atggagatga agcaggtctt tgtggaggtg ttgacccaga taatagaaga
     8101 acttatccat ggaaaaatga agacgaagat atgcttaatt tttatagaga tgttataaga
     8161 attagaaata agaataaact tttaagttct ggaaatacag aatttatata tactaataat
     8221 gattctgtat tttcttttat tagagttaat gaaaataatg atagaatgtt aattttagta
     8281 aatagaagtg aaaatgtgga aagtatatca ttatgtatag agagtagttt tattgaggaa
     8341 atacctataa agtatagtct taaaaatgca aatagtacta tacaaattga aaataatgag
     8401 ttgaaagtag atttagactc taaatcattt agaattttta gagtaaatta aatatctttt
     8461 tttagaaaaa taaatagaaa ataaggtgaa tgtggaaaga gttttgtttt atcaaaactt
     8521 tttctacttt ttttgtataa attatcataa gaattttagt atttcaaaat attacaaaga
     8581 agtataaaaa atatcataat tgtgatatta tataaattag taagataaaa ctgaactctc
     8641 taccaaagtt gtagggagat ttaactttta taatcttaat atggaggaac gtcttatgaa
     8701 ggtagatcca cttacaactc aagtatatga ctatatatca aagaaaatcc aaaatggaga
     8761 atatgaagct aatcagagaa ttactgaatc tgagatttgt aaatctatcg gagttagtag
     8821 aacaccagcg agagaagcat taactaggtt agcaggtgaa aatttactag aaaaaatacc
     8881 taataaggga tttgtagtaa aagaatttca ggaaaaggag aaattagaca cctattccgt
     8941 aattggagta ttggatgcgt tagccggttc ttcagcatta caaaatttaa ctgaatcaga
     9001 cctagtaaaa atggaagaat taacagaaat gatggcggtc tctataaagt ataaaaatta
     9061 caatagctat ttaaaattaa gtaatgaatt tcacgatata tacataacta aatcagataa
     9121 tcaggtgtta gtaaatctat tgaactcttt aagatataat tttatgtcaa agtcatatac
     9181 tagtgataat gaagatgagt tatataaaat gttgacatac agcaataatc aacatattga
     9241 agtagtaaaa tctatgaggg agaatgattt agaaaatgtt gaaagaattt tgagagaaca
     9301 ttggaaaacg atacctatgg aagagatgaa aaaagagaag cttttataaa gtttctcttt
     9361 attttttata ccattttatc actatttttt tgaattatta agtagaaaat aataattaat
     9421 ttaaacttga ggaggaaaac taatatgtat ccaaataaag aaattgcaat agaagagtta
     9481 gaagtggctg gcaaaatgaa tcccggtcca tggataaaac attcttacaa tgttgctaat
     9541 gtagctaaat tgattgcaga gcaatgtgaa aatttgaata gtgaaaaggc ctttgtatgt
     9601 ggattattac atgacattgg aagaagaact ggtatttctt ctgtaaggca tattattgat
     9661 ggatatgatt atgttatttc taagggatgg gatgaagtgg cgagggtatg tttgacacat
     9721 tcttttcctg ttaaggatat agaagctgat attggaaata aagatattag taaagaacag
     9781 tatgatttta tcaatcacta tttaaacaac cttgaatata acgattatga taagttgatt
     9841 attctttgtg atgcattagc agatgcaaat gggttttgta ttttagaaaa aagatttgtt
     9901 gatacaacac gaagatatgg aatatatcca ttttcagttg aacgatggaa taagacttat
     9961 gagtataaag aatatttcga gaaaataatc aacaagtcta tatatacatt gttacccaat
    10021 attgaaaaat ctatatatta ttaaatccta agttaataat ttaatatcca gtatcaccag
    10081 cagttggtca ttatgattga ctgcttttat tatgcttata ttaaaaaaat acactatggt
    10141 ttgtgtatat caaagttata tggaatgaaa agagaattta ttttatcaat taaaaaattt
    10201 aataaatttt a
//
LOCUS       DAMJWC010000107        10148 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMJWC010000107 DAMJWC010000000
VERSION     DAMJWC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10148
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.112"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(33..1787)
                     /locus_tag="PC503_003387"
     CDS             complement(33..1787)
                     /locus_tag="PC503_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF2529341.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLIMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTESLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(2005..2895)
                     /locus_tag="PC503_003388"
     CDS             complement(2005..2895)
                     /locus_tag="PC503_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2529342.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            3044..3904
                     /locus_tag="PC503_003389"
     CDS             3044..3904
                     /locus_tag="PC503_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2529343.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            4360..4926
                     /locus_tag="PC503_003390"
     CDS             4360..4926
                     /locus_tag="PC503_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2529344.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQINNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            4966..5547
                     /locus_tag="PC503_003391"
     CDS             4966..5547
                     /locus_tag="PC503_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2529345.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(5604..6521)
                     /locus_tag="PC503_003392"
     CDS             complement(5604..6521)
                     /locus_tag="PC503_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2529346.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            6651..8282
                     /locus_tag="PC503_003393"
     CDS             6651..8282
                     /locus_tag="PC503_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2529347.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            8285..9232
                     /locus_tag="PC503_003394"
     CDS             8285..9232
                     /locus_tag="PC503_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF2529348.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLANTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(9517..9780)
                     /locus_tag="PC503_003395"
     CDS             complement(9517..9780)
                     /locus_tag="PC503_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF2529349.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(9879..10124)
                     /locus_tag="PC503_003396"
     CDS             complement(9879..10124)
                     /locus_tag="PC503_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529350.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         3544 a         1460 c         1418 g         3726 t
ORIGIN      
        1 taaaactata taaactttat tttcatatgt ttttattctc caattgatat attatttatg
       61 ccattatttt taacttcaat aattggttgt ccatttccta aaatataatc tttagaccaa
      121 ccttctggca atttatttat cccatttcca attaacttca agtgtaaatt tgatggttct
      181 tttttcagat ttaatttaaa tattccatca aaggtacctt tattatcgct tccaaataaa
      241 cttatattgc catttatatt cgtagctgtt acatttacaa ttccattgtt tgctctaaat
      301 tttatttcag atgatatagt ttcagctgtt acacctgaaa tcccactatt agtatttata
      361 ttgaaaggat ttgttacatt gttatcaaca atgttagcaa tcccgtcatt gacatcaaca
      421 gtagctcctc ctttaatatt ataaagttct actgaaccac tttcaacatc tactttaaaa
      481 ttagaataca ttttatcggg aactccaatt tttatcacat ttaccatcct atctttattt
      541 gcatttatca tattgtcgcc attcatatct tgcaaatcac tatctttctt atctattttt
      601 ttcttagcac ttacaactag ctttccattt tttatattat tagaagaatt ttctttatat
      661 acagaaaaag tacaattttt ttcattagtt acacttacgt aatcaaactc aaatttattg
      721 gtattcgtct tttcaacaac cacacctaaa ttatctgatt ctataagtat ttcagaaact
      781 tcatttcctt caactgaagt taagtgtttt aaaatatttg gagtcatatc catattatta
      841 tatttaatca tatctaaaca ctgtttatat atattggcat caatacctcc aacttttgtt
      901 atacttttag ctccttttaa aataccttta ttacttccat cagcaactaa aacgattggt
      961 ttttctttgg ctaaaggaga taatgttagt gcatctacta attgatatcc atttgttata
     1021 taaaaatctg tcgctccatt ataaaacttt tccattacct ttttattggt ctcaaatcta
     1081 tcatttcctc cgattctagt tgctttagtt tcatttacta aatcctcatt tatcgcagat
     1141 ttgccaccta tagcgtaaac atttaaactt tcagtcttaa atggaactga tttcccatct
     1201 gtaagtatta tagctccttt attttttgca actacaggtg ctatactcat agcatcagcc
     1261 tctcctacaa atccatttgt aagcattacc tcttttacac tacttacttc atttattttt
     1321 ttagctacat tataactagt ttcaattcta ttgttaccat ttattctttc cacttgaata
     1381 ccttttcttt ttatatcttt ttctactgaa ttttcaatag tattataacc accaattata
     1441 tatacttttt ttacaacatt taaactctta ttatctagtc tatttaaagt agcttttggt
     1501 atttcacttt ttttagtcaa aagtattggt gcgttaatag ctccagctaa tccacttgat
     1561 gaaagcccat cagataaatt tttatctcca ttaactaata ttacagtatc ataagtttgt
     1621 ctatctgcta taagtcctgc tgtttcatat ctatcaattc ctattattga atcttcttta
     1681 atctgtgcat ttgcagttaa attattaaaa agaaacataa tcaaaactaa aattaatata
     1741 cttagttttt tactgaattt tttgaatttt ttattcataa tatacactat tcctcctgta
     1801 aattaaggtc tttaatttgc ttataaatta tccccttatt tacaaataat aacataatat
     1861 tatagtaacg tatatattac cttaaaatta tcagtaactt tatatcaatc atcttagctt
     1921 atttatataa atttttttat attacttttc aaataacagt catactaaaa caatttcatc
     1981 atataatttg aaaattatta ctatttacac agcttttatc atcatcttac caccatcaaa
     2041 tatatattca accatattat tctcatataa ataagttata taagaacgta ttgtacttcc
     2101 aaccaacaca tattgattag catcaagctt gacattgtac aaatcacaca ttttttcaat
     2161 aacttcatca atcataactg gctcataaca aaccttttta atattatcta ttatttcttc
     2221 catcttcttc ttattaatat taattaaact ttttatatct gtagttttga cagagtgact
     2281 tggaacaaag aaatcagcct ctaacattct caatttttct agtgtcttaa actgtgaatc
     2341 tatatccagt aggaagaaaa aatgatattt agtaattata ttctctggtg taagactatc
     2401 tgcaacaaac aaaacattat ctggagttct aacaccaatc atttcaaaat aatgacctgg
     2461 aagagaaatc gcttcaagtt ctgtatctac aattttgcca tttgaaggga taatataatc
     2521 aacttcactt tcctttgcta ataaaaattt attcttcagt gctttacttg gatagccacc
     2581 atataaaaat gctgattcta atattggatt ttctgtaaaa tatccttcaa ttttagtcgt
     2641 agcaatcttg cattttgttt gattcttcaa atatgcattt cctcctatat ggtctgcatt
     2701 tgaatgagtg tttattatta atttaggatt taaattatgt tcttctaata atcttaaaac
     2761 ttgtctagct gtatccttat tatttccact gtcaattaaa attgcatcct taccatctac
     2821 gtatacacct actattgtag ggagtggaat ataatatgta tttcctttta tatgttctag
     2881 agttaattta gccattttat aacctccctt taaatttact tttaattata gcattaattt
     2941 tctgaaaatt ccaatcaaat tgtttttata atatattttt atttctttta ttaaaaattg
     3001 gaaaaactat ataatatata ttataatcta tatataagga gtgatgttat tgaaaaaaga
     3061 tagaataact ttttcagaaa ttttaatatt aattgtaggc tgtatattaa tggccatttc
     3121 tcttaactta ttttttaatc cacatgcaat cgctgctggt ggtataacag gacttggagt
     3181 tgttttaaat tcattattcg gtgtagaact ttggattgtc aatttacttt taaatgttcc
     3241 attattcata tttgcttaca aaatactttc aaaaaaagat tgttttaaaa cggttttagg
     3301 aataattttt cttaccatag cacttaagct tactgcaaat atggctacat tagatataac
     3361 aaatgatatg tatcttgcaa ttatatctgg ttctatttta atgggagttg gtcaaggact
     3421 tatttttaga ataaatggct ctacaggtgg aactgattta atggcactcc tactaaataa
     3481 atattttcct acatttagta tacctgtttt aatgggtatt gtagactgcg ttgtagttgt
     3541 tttatcaggt atagtaaata gacaggttga aattgcactt tattcaactg tggctttata
     3601 cattttagta aaagttagtg acttgcttat tgaaggattt aattattcca aatcattcac
     3661 tattatatct gacctttcaa aagatataag taaaaaaata atggaagatt tagatagagg
     3721 tgcaactatt ctaaaaggag aaggtgcata tactggagaa aataaaaatg tacttttagt
     3781 agtagttgaa aagaaagaag ttgtcgaatt gaaaaaatta gtaaaaaatg tcgaccctaa
     3841 tgcttttatt ataattacag atatacatga agctttaggt aatggattta aaaaaataga
     3901 ataactaaca aataaatagc aagtataatt aacatataca aattcaactt tttatatgtt
     3961 atattatact tgctatttat atattatact tgctatttat atattataat tgttgttttt
     4021 aagataaaaa ttaaatgtat caattattgt tttatacaag tatttccaaa tccgttctca
     4081 tttagatagt atgcttagaa attttagaat tattgagtct aactttatta cttactttac
     4141 tttataacaa tcaaatacaa atttaaatat tataaaacta caaaataatt taaagcatat
     4201 aatgtcaata tgtttaaatt ataaaatatt catgtagtta tataataaat aatttataaa
     4261 tatagccaac ttagcctaaa tacgtatata atatagctaa tatggttctt atacttgata
     4321 ccatcaataa aactaaaaat ataaaaagga gaacttaaaa tgagtgttag tttacaaaaa
     4381 ggacaaagag ttagcttagt aaaagataat aatcctgtaa aaaatctagt agtaggctta
     4441 ggatgggata tgaataaatt gggtaaaaaa aattatgacc tagatgcatt tgcaatagca
     4501 ttgactaacc aagataaaat gaatgttaga ggtgacttgg tttattttgg aaatcttaaa
     4561 cacccttcta aagctattat acacactgga gataacttaa ctggaaaagg tgaaggtgat
     4621 gatgaacaaa taattgttaa tttagaagac atacctgaat atgtacataa aatagttttt
     4681 ggagtttcta tatacaaagc taaaaaaaga gaccaggatt ttggtcaaat aaacaactct
     4741 tttataagat taattgattc aaattccaag caagaattat ttaaatataa tcttcaagaa
     4801 gacttttctg gtaaagtaac agttttggca ggagaaattt atcgtagaaa tgaagaatgg
     4861 aaatttaatg ctttaggaat tggtcaaaat gaagagcttc gtgaattaat taatacatat
     4921 aagtaataat tacaataaaa aatttataat gaggagttgg tttaaatggg tataacttta
     4981 gcaaaaggac aaaaagtaag tttaacaaaa agtaaccctg gtctaaaaaa agtaatagta
     5041 ggactaggat gggatattaa taaatatgat ggtggctttg atttcgattt agatgcctct
     5101 gcatttttaa ctggaactga tggaaaagta acgaatgatg gagactttat attctataat
     5161 aatttaaaac acgcttctgg agctgttgaa tatatgggtg ataatagaac aggtgttggt
     5221 gatggtgatg atgaacaaat aaatgtagac ttatctaaaa tacctcaaaa tattgctaaa
     5281 atatcattta gtgttactat aaatgaagca attacaagaa gacaaaattt cggacaagtt
     5341 gaaaattcat atataagaat atataatgaa gaaactaatg aggaacttat taaatatgaa
     5401 ttgggtgaag attttagcat agaaacagca atagttgtgg cagaactata tagacataat
     5461 ggagagtgga aatttaatgc tttaggttct ggatttgagg atggacttgc aggattgtgt
     5521 aaaaattttg gcgttaatat aggctaatat atctaaataa aaataagagt atatcaatat
     5581 actcttattt ttatttagat atattataaa ctgtttacac ttctactctt ctttctcgct
     5641 tgttttttcc catattctac tgaaatatca aaaaatgctg aaatattttc tgtaaaaaac
     5701 ttgcttctat gatatgcaat atcaaatgtc ctatgtaaat taataccttc aatatcacaa
     5761 gcccacaaaa gatgcttttt taaataatcc tcaataagta attcggatat aactgcaatg
     5821 ccaaaattat ctacaactgc tcttaatata gcttcagagt tataacatga ccatctaata
     5881 ttcattggga tttttaattc ttttaattgc ttttctaatt gtgctcttgt accacttccc
     5941 aattcacgca taattaatgg ttgatttgaa agttctgaaa cttttataga gtctctttta
     6001 taaaactcat gcttgtgtga acatataagt acaagattat cattaataat gctttttgta
     6061 acaatatctg ggtgcttaat ttttccttct acaatcgcaa tatctaattc actattaagt
     6121 aatttttttg caatcagtct tgtatcttct acaaatactt caggttctat aagaggattt
     6181 accttgtata attctaacat tattggactt attacacatg taccaacagt tactgttgcc
     6241 ccaactctta tacggatatt ttttgcacaa tgcttcatac aatcattcat ttcttcattt
     6301 acagctaaaa gatgcctccc atatccaaga agttttttcc ctgcctcagt taaatataat
     6361 ttttttgaaa ttctatcaaa tagcttaaca ccatactctt tttctatttc tgaaatagct
     6421 tggctaactg atgactgggt aatatacata tttcttgcta cttcactcat tttaccacat
     6481 tcagcaacct taacaaagat ttcaagacta cgaattgtca tattatcaca accttagcaa
     6541 acattagtaa atgcttatga ttttattaat attttagtat tttacaaata tattgtcaag
     6601 aagtataatt ttattataga gttataaagt agattggagt gtgatatatt gtgaaagtat
     6661 taattatagg tggagttgct gctggaacaa aaactgctgc aaaaataaaa cgtgaaatgg
     6721 gtgataattg ctctgttaca atactaaata aaggtgatga tatttcttat gcaggttgtg
     6781 gtcttccata ttacgttggt aagataattg aagataaatc atctttaatc gtaaatacac
     6841 ctgaaagttt ttctaaacta acaggagcag aagttcgttg tggagttgaa gttacatcta
     6901 ttgatagaaa tgcaaaacaa gtaactttga aaacgctttc aacaggagaa aaagaaaatc
     6961 taagctatga caaacttgta attgctacag gggcagaccc aataaaacca ccaatacctg
     7021 gaatagattt acctggagta ttctttatgc gtactccaaa tgatgctata aaactaagag
     7081 attctattga aaacggtatt aagagagctg ttgttattgg tggaggtttc attggtcttg
     7141 aaattgctga aaatctttct gcaatgggta tacgtgtaag tgttgttgat atggctgaac
     7201 atgttatgcc tggatttgat actgattttg ctgaatacgt tgaaaatcat atggctgata
     7261 aaggcataat gatttttaca ggtgaccagg ttgtaggtat tgaaggtgaa aataaagttg
     7321 aaaaacttcg tactaaaaat agagctatta aaacagattt agtggttatg tcagttggaa
     7381 tccgtcctaa cacaggtttt ctaaaagaca caggtttaga atttgcccct aataatacaa
     7441 ttattgcaga tgaatatatg cttacaaatg acaaagatat atatgtagtt ggagactgtg
     7501 cttttgtaaa aaattcttta acaaataaac ctacatggtc acctatgggg tcatctgcaa
     7561 atcatgaggg tagaatttgc gcacaaaata tatctggaaa atctaaaact tacaatggtg
     7621 ttcttggaac aacagtagta aaattacctg agctcaatgc aggaaaaaca ggtctaagta
     7681 aagaaatagc tgaaaaagaa ggttataatg tttgctctgt aaccatagct actgatgata
     7741 aagctcatta ttatccaggt gcatctaatt ttattataag aatggttgct gaaaaaaata
     7801 ctagaaaatt attaggtgtt caagttatgg gacctggagc ggttgataaa atagtagata
     7861 tcgctgctac tgcaataact ttaggcgctg acctttattc attagaaagt atggaccttg
     7921 catatgcacc acctttttca acagctattc acccttttgt agtggcagta aatgttttac
     7981 aaaataaact taatggagaa cttgatagtg ttttacttga cgaaattgag gattttgaca
     8041 gttggactaa acttgatgtt tcaaaagctc cttctattcc tagtttacgt tatattcctg
     8101 ttggtgaaat taatggagaa attgaaggtc ttgctaagga tgaaaaaatt cttcttatat
     8161 gtgctaaagg taaaaatagc tatatggcgc aaaatcgctt aagacgcttt ggctatacaa
     8221 atacgaaagt tcttgaaggt ggaatactat tttatccaaa tcttaaggta atggaggagt
     8281 aaatatgagt aatgttacag cagaacaaaa aaaggaagta aaaggtagag gttttctacc
     8341 aagcagggat ggagaacatt ttgcagcacg tataataact gtaaatggtg taataaatgc
     8401 atcacaagca aaaaaaattg cagaagctgc tgaaaaattc ggaaacggtc agttagcatt
     8461 tactactaga ctaacagtag aattacctgg tgtaaaattt gaagatattg aagctctaag
     8521 tgaatttatt gctagcgaaa atctaataac aggtggaact ggatcaaggg ttcgtcctgt
     8581 tgtggcttgt aaaggtactg tttgtgttca tggtctagct aatacacagg cacttgctgc
     8641 tgaaatacat gaagaatttt acaaaaattg gtatgatgta aaactacctc ataagttcaa
     8701 aattggtgtt ggtggatgcc ctaataactg tattaaacct gacctaaacg atcttggaat
     8761 tgttggtcaa cgtgtacctg actatgattc agagctttgt gttggttgta aaaaatgtgc
     8821 tgttgtagag gtctgtcctg ttaaagcagc taaattaaca gataaaggta aacttgaaat
     8881 agatagtaat ctatgtaata actgtggtaa gtgtatagaa agttgtaatt ttgatagtat
     8941 tgaagaaaaa gaatctggtt ataaagtcta tataggaggg aaatggggaa aatcagttcg
     9001 tcctggaaca cagattgata gattattttc aaaagaggaa cttatgactt taattgaaaa
     9061 agcaattctt ttatttagag aacagggtaa cacaggtgaa cgttttggaa taactatcga
     9121 tagaatcggt gctgataaat ttatagaaat gcttttatca gatgaagttt tggaaagaaa
     9181 agaagagata ctagaggctc ttttacacct tacaggtgga gctgtatgct aacaataaat
     9241 attttaattg tacagataac ctatggaaaa aattttagtt aagaataatt aaaattctat
     9301 atatgatata tgataaatga ggctatctca aaacacagat acgcctcttt ttcattgttg
     9361 aaatgataaa gtatatttga gttcatataa aaaagagtgt ctcatgaatt ataaaattca
     9421 ttttgaggca cccacattat tttataataa ttgcttatta attttatttt aactatataa
     9481 aatgtacaaa aattaagaat atccaatatt ctaaaattaa ttttgaattg tattgattga
     9541 aaagtttact attccactat ttccatcttg atttactact agataccatg ttccagtatt
     9601 aggaactctc attctacatg gatttttctt tgcaaatcca ccatagtaat cataatttct
     9661 ttgattttta aatttcacat aatttatatg gtctaacaat attacattgg cttgtttctc
     9721 taaatttacc tctacaatat cccctttttt taagttcatc ttactataac tatattccat
     9781 tgaattactc ctccagtatc gaataatctt tgttatttac tcatctcaaa tatgtaaaaa
     9841 ttcatttaaa atattacaaa tactatataa ttagactatt atccagtttt aaccttattt
     9901 actacaatcc aaaggttatt aaaaatatta ttggcaacaa cttctccatc ccatacaact
     9961 ctttcttctt tattttctaa taaagcatag tacccagagt cagaactttc atctttatag
    10021 actgtaacat aaaactcttc atcactatat tcaggtatat ttttaaagtc ttcagatatt
    10081 ttacatgtta atatataacc ttctaattct tcatctataa acaaagcaat tcctccaatc
    10141 tctatatt
//
LOCUS       DAMJWC010000108         9192 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMJWC010000108 DAMJWC010000000
VERSION     DAMJWC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.113"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            393..1598
                     /locus_tag="PC503_003397"
     CDS             393..1598
                     /locus_tag="PC503_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2529351.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKG
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="PC503_003398"
     CDS             complement(1669..1890)
                     /locus_tag="PC503_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529352.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC503_003399"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="PC503_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF2529353.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="PC503_003400"
     CDS             complement(2643..2993)
                     /locus_tag="PC503_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF2529354.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC503_003401"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="PC503_003401"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF2529355.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="PC503_003402"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC503_003402"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="PC503_003403"
     tRNA            complement(5068..5159)
                     /locus_tag="PC503_003403"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="PC503_003404"
     CDS             complement(5160..5615)
                     /locus_tag="PC503_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF2529356.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC503_003405"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="PC503_003405"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2529357.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="PC503_003406"
     CDS             complement(7666..8547)
                     /locus_tag="PC503_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2529358.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="PC503_003407"
     CDS             complement(8559..9068)
                     /locus_tag="PC503_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF2529359.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2943 a         1599 c          973 g         3677 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt atcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa acttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaaggtattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatggtact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctactataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt ttttaaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctatatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tattgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatctct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtaac
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta aaaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaaatata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta cgatgacatc ttttataata ccacctaaat ccacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag ac
//
LOCUS       DAMJWC010000109         8954 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMJWC010000109 DAMJWC010000000
VERSION     DAMJWC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8954
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.114"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(35..643)
                     /locus_tag="PC503_003408"
     CDS             complement(35..643)
                     /locus_tag="PC503_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF2529360.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(752..3490)
                     /locus_tag="PC503_003409"
     CDS             complement(752..3490)
                     /locus_tag="PC503_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF2529361.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLKDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3638..4429)
                     /locus_tag="PC503_003410"
     CDS             complement(3638..4429)
                     /locus_tag="PC503_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2529362.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4465..5121)
                     /locus_tag="PC503_003411"
     CDS             complement(4465..5121)
                     /locus_tag="PC503_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529363.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5114..6079)
                     /locus_tag="PC503_003412"
     CDS             complement(5114..6079)
                     /locus_tag="PC503_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF2529364.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6185..6291)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6581..7525)
                     /locus_tag="PC503_003413"
     CDS             complement(6581..7525)
                     /locus_tag="PC503_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2529365.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7636..8103
                     /locus_tag="PC503_003414"
     CDS             7636..8103
                     /locus_tag="PC503_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529366.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNNDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8273..8872)
                     /locus_tag="PC503_003415"
     CDS             complement(8273..8872)
                     /locus_tag="PC503_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529367.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2891 a         1484 c          874 g         3705 t
ORIGIN      
        1 ttcctataga tacatatctt acctatataa aaacttattc tatataaaaa cgccataaaa
       61 aatcttttgc ttcttctgca taatctatat ttatacgttt actagttttt atatctaact
      121 catctttact aaatactttt tttcctttat catcataata aaaatcactt atatataatt
      181 cttcacccat tatactctta ctatttagac ttctatctat ttttaaagct ttgcaaagtt
      241 ttcctggtcc gttagtaata ttttttactt gatatttact caactcagtg taagctttgt
      301 tgtatctatt catagatatc tcatctaaag aagttatagg ctctacccct cttattaata
      361 cacactctgg cacattttct atatttgcag ataaattcaa gcaattatac ataccataaa
      421 ttaaataaac atatatatgt ccaccatcta aatataatgg cttagttcta tctgtctttt
      481 tattgccata tacatgtgct cctttatcat ttacacccat gtatgcttct gtctctatga
      541 ttttggtaac aattacttta ttttcatatt tccttattag atatttacct aatattgatt
      601 tggctaaatc aattccattt tttctaaaaa aatccttttc caaaatttca cctcataaaa
      661 tttatttaaa acgcatcaaa tacaactaaa gtaataaata aaattaactc ttattaatgt
      721 gatatatata aacaataaat ttagacattt attatttata tatatcaaaa aattctatct
      781 caaacttttc aatattatca ttgtaatttg aattatcata tacttcttca acaacctctt
      841 taattgggaa tataactttt acattagttc cttctcctac cttactatct atgtaaatct
      901 tcccattttg aatttcaatc aatgattttg taaggcataa acctatacca cttccaaatt
      961 catttgatat accactgttt tcaatttgtt taaatcgatt aaatatatcc tttaattttt
     1021 ctttgtctat gcccactcca gtatctttta taattatctc tactgtttcg tcttttttat
     1081 atatacctac aaggatttct cctccttcta aagtaaattt tatagcattt gataatatat
     1141 ttagtattat tctttctatc gattctgggt caagccctac cataacagtt tcttcatctg
     1201 tatcaaaaat taaatctatt cctttagact tagcataact actaatagat gtaactattc
     1261 tttctgttat gtcaataata tcaaaattaa ctgctttaat cttatatatg tctgacttaa
     1321 cttgagaaat atttattata ttatctatta atctcaataa tctaaacata ttttgtttag
     1381 ttatttttat atgttctttt agtatatcct gaaaatcaat tatttttcct tttttataaa
     1441 ggttttcaat aagttgaact gaactatata tattatttaa aggtgtctta agttcatgag
     1501 atatattagc ataaaactcc atcttcattt ggtcatactg tctttgtttt attaatgctt
     1561 ttttaagtct ttcagactct ctttgcacac ttaaatcttt aataattctc actctacttc
     1621 ttttctgtcc aaagtataat gttcttgata tcatttttac ttctttaatg tgattatttt
     1681 catttactat atggatactc ttctctcttt ctcctatatt taaattgttt atgtattttt
     1741 ttactaatat atttctatat ttttgtgttg taactcctaa tacatcacta gaaattccga
     1801 acaactctct aaaggctcta tttgtatata gtactcttga tgtacttaaa tcctcaagaa
     1861 aaatagcctc tggtataaca tccagtaatt tttcatatat tattttttgt tcatttactg
     1921 ttctaagaat atttatctct ttagttatat ctctaaatgt aagcaattta aagagtttat
     1981 tatctgacca atagtctcca actctaactt cttcaacatg ttcttcacct tctgagtcag
     2041 acatcacaaa attaactata cagtttgctg tgtcattgta acttactatt tcagctttct
     2101 tttcttgtgt tagatttaat cttttaaatt ccctattgtc aaagaaatct atgttaaaag
     2161 tttcaaaata ttgttctaat gtcatatcga ctaaatcact tgaaacacat ttaaaactct
     2221 tttcatattt tttatttata cttattacct tattcttctt tatgccacct tcagcacttc
     2281 ttacaagtat aggagatgga atatttagta taatgttttc atagtcttta tttatatttc
     2341 ttatttcttc atctattttg atttcatttg taatatcatt taaacttatt aagtaattgc
     2401 tttcgtcttt attattactt aaacttaaca aataaatttt atcatttaac tctaccagtt
     2461 tatcaattat acttatatcg ttatcaaatt tcttcaattt ttcagcaact ttttcatctt
     2521 cctttataaa agttaatatt ttataataat tattcatatc ctttgaaaat tcatctttaa
     2581 atttattatt tgtgtaactt atattaaaat catagtctgt tactatccat acatttggta
     2641 ttgtatccag agcttgtcta agtaattctt ttctctggtc tatgtagttt tttaatgttc
     2701 tttgtataat catatccttt tctattgcta aatttatctt tcctaattgc tctgactttt
     2761 tacttaattt tttattgatt gaatcaagtt cataatatgg atacactact ctattattaa
     2821 gactgtatac atatacataa taagtatggt tacataatag taaatatatt actcctatta
     2881 atctatctga atctactata ttaatcttag aaattgctac aaaacatata atagttgtaa
     2941 aaaaaacaaa atatgttaaa tcttttatta acttatagtg ctcaatgtta ctatcaagtt
     3001 tattcaacaa atatagtaaa ttaaacatag atatacaaat attaattaat ataataatca
     3061 tattccagtt aatatcacta aaaatatttc ttataaagta atctaatatc acaaaagcac
     3121 tataaaaaat tagtattggg cttattctta gtttttttac tttagaaatg gttaagtata
     3181 taaaagtaga catattaatt atgcttaagt taagcaatac aatttggaat ttttgaattt
     3241 ttaaatttac tactcctaaa atacttacaa aaactaatac aagacaccct actttcaata
     3301 tatttataaa ttcatctgtt ttaaagctac ttatataaac tatagaatat ccaaatatcc
     3361 aaagtaaaat tattctatac atatttatag aaactgtata caaatttata tttaaaagtg
     3421 caataaccaa aaataaccca ttagctagta tatagacctt attcttactt aaagttcctt
     3481 tagattccat attccccacc acttcttcat ttttatatag ttttacctat aaatatgtta
     3541 ccacaattct tccaaaaaat ttgtcacttt ctagttataa aaaaaaatga gtaaatattt
     3601 ttaattttac tcattttgta gattttgtat attcagttta aaaagctgga actatacttc
     3661 ctttatattc atcttgtata aattttttaa cttctttact attcatagcc tctgataaag
     3721 ccttaatctt atcactatct ttattatttt ctctacaagc tattatattt acatatggag
     3781 aatcacttga ttctattact attgcatcct tagtaggatt taagttagct gttaaagcat
     3841 aattagaatt tattactgct ccgtcaacat cttttaatac tgttggtaat tgctctgcat
     3901 tcatttcttt tattactata tttttaggat ttttagttat atctttttta gttataagct
     3961 ctccatcttt tacttctatc aatttatttt ttgctaataa tttaagtgct ctagctccat
     4021 tagttgcatc atttggcaca gctataacag ctccatcttt taattcatct aatgacttaa
     4081 ctttttctga atagaatccc attggctcta tatgaacttt agatgtataa gtaagtttat
     4141 atcctttctc cttcacagtt tcctctaaaa atggaatatg ttgaaagaag ttagcatcca
     4201 aagacccttc atctaaagct gtatttggaa gtacataatc atcaaatatt tttacttcta
     4261 aatcatatcc tttttctttt aacaaaggtt ttgcaacttc caatatcttt gcatgtggat
     4321 ttgatgaagc tcctactagt atttttttat cctctttgtt tgaacaacct actgctgata
     4381 ttgctattgc tgacaccaat gctactgata ataatttctt taatttcatt tttactcccc
     4441 ctctttaaaa tgtttataat taatttattt tagtttctta taagccagat ttcctactcc
     4501 ctggattatc tgaactaata ttataagtgc tattacagta tataccatta ctgctgtatc
     4561 aaatctttga tatccataaa taagtgctat attacctaat cctccagctc ctactgcacc
     4621 tgccatagct gtataaccaa gtatagatat tattgataat gtaattccag atactattga
     4681 aggcatagct tcctttatca taactttaaa tactatttgt ctttttgtag ctccaaaaga
     4741 ttttgctgct tctatcaatc ctttatcaac ttcatttaat gagctttcta taattctagc
     4801 gataaacggt gctgccccaa tagttattgg cactattgca gcagtttccc ctatacttgt
     4861 tccaacgatt aatctagtta ttggaatcat tgcaactata agtatcataa atgggaaact
     4921 tctaaatata tttactataa atcctaatgc actatttatt gtgctatttg gttttaatcc
     4981 atctggtttt gtaactacta atatgattgc taatataaat cctaatattg ttgccactat
     5041 agttggtact ataaccatat acaaagtttg taacaatgca tttggaaata gtgttgttaa
     5101 aaagtcaatt aaactattca tttatcattt cctcccatct tatgccctta ctagttagat
     5161 attgttttac ttgctctcca cttttatctg aaatgtttat aataagtgaa cctaaaatat
     5221 catctttaaa ttgttctaat ttcccaaata ttatagacac atctatattt agttctcttg
     5281 ccatagtcgt aataatagct tcattagaaa tatctttagg gaatagtatc tttatatttg
     5341 ttccttttgg caatattata ctttcttcac ctattaattt tctaagtcct ttagtatttc
     5401 ttaagaatat ttcttctgta tctcctacct ctaatacttc tccattttcc attattgcta
     5461 ctcttccaca aatctgcttt ataacttcca tttgatgagt tacaactatt attgttattc
     5521 ccaatttttt atttatatct tcaagcaatg aaagaattga ctttgtagta tttgggtcta
     5581 atgctgaagt cgcttcatca caaagaagta cttgtggatt tagtgctaaa gctctagcaa
     5641 ttgcaaccct ttgtttttgt ccgccactta gatttctggg tttatcattt ttcttttcag
     5701 atattccaac tacttctaat aactctaaaa ctcttttttt aatttctgcc tttgagtatc
     5761 caaaacattc taatggcaat gctacattat caaatacagt ttttctttca agcaatgaaa
     5821 agtgttgaaa aatcattcct aactcttttc ttaaatctct catttgcttt tcattcaatg
     5881 actttacttc tttatcagaa acaagtacac tgccttcttg gtattcttct aatccgttta
     5941 tacatctcag tagtgttgat ttccctgcac cactatgacc tattattcca aaaatttctc
     6001 cagattctat ttcaatactt acatctttaa gcacttgaat ctttccataa tacttattaa
     6061 cattttttat gctaatcata aaatttcctc ccatatattc tgctcagttt ttatgtttat
     6121 cctctcttat gtattacaac aaaataaaag cccgagtata aactcaggct tagaaagcta
     6181 tttatactca tctatcaact atattagttg caggatttag caccaatgta tataaaatat
     6241 actggttgcc gggtttcaaa gggccagtcc ctccaccact cttgataaga cgttatttaa
     6301 tttaattcta ttatcatttg ttgctatgtt atatatgata tattcattaa tagtatttgt
     6361 caataaattt atttaaattt tttatttttt attatcgtta attaactatt tttaattagt
     6421 tttctagctc ctaacacttt atattttaat gtctatataa ctatagaaca tcattataag
     6481 aaataaatta aataacatca atctatctaa atcatctgta aagtaaatta agaaaattaa
     6541 cattttatcc aaactctatc ctactattaa ataaaataat ttaaatacaa tgatgattat
     6601 atagctctag tactttagac tttatcaaat gtttaagttc tataggttct attattgtag
     6661 catttttccc aaaagttaaa aaatattcag ccacccagtt aagtgtagat tttggtatat
     6721 acatatctat gtatccacct ttagacaaga ttttcaaccc tcttgccaac aaaaattctg
     6781 tttcacaacg ttttactccc tcatctgtca aattaatttt aatatgataa tctgtaccta
     6841 cttccatatt cttaagataa tcatgtatag aagataaaac cttatatttc ttacttgata
     6901 agttttctat actcaaaatc ttcacaattc tgtctacacg aaattcctta atagattctg
     6961 attttataca gtaagctgga caataccaaa gtccattcat ggcatacaaa ccaataggaa
     7021 caatggtacg tacactattt ttttgctttg atgaatattc aattttaatt gtaaattcat
     7081 tcattactat attaaacaat tctttcaata atggtgttga acagtgccta tctggtgtcc
     7141 aaaaaacaaa tttacgcctt atattctcaa tattatattg aatatcattt ggtatacaat
     7201 ttaaaaattt ttttaaaaca gaaatagttt cttgctcaaa tggcaaatca ttataatatt
     7261 ctagtgactg atatgcaaag aatatagatt ttacctcact ttctgaaaat gcaatcggtg
     7321 gaagtatacg ctctttaagt acatgatatc caccagccgc tccaactttt gaatataatg
     7381 gaaatccaat actctccagc acctgtaaat ctcttagtat agtacgtttt gatacagaaa
     7441 attcttctgc taattctcct gctgtaaaac ttctttttgc atttattgtt atcatcagtt
     7501 caattaaacg ctcagctctt gacatattta tactcctaat ttaaatatag tgacaataat
     7561 tgtcactatt atatgataag atattcttgc atctaaagca ataataatag taaagaaaga
     7621 agggattgat actttatgga aaatgatact attaaggctg atgatattct caattattgt
     7681 ctatcaaact tagatgatgt tgtactaatg gatagttggg gggaacgagc aatttactac
     7741 aatcctaatg gtgttttaaa gcgaggggta tatgttctta ccattaagga aaaagacagt
     7801 aataatgata aaggttcgtt agttagtcgt ccaaatgtat accgtgtgaa tataggatta
     7861 aaaaaagaaa cttttattga aatgtttgga tatattccaa agcgtccagg tgtaggtcaa
     7921 atagttgata tggattttga ttttacaaaa ttggacacaa tcatgccaca tcctatctac
     7981 tcatggatgg gatggatatg tgtcctaagc cctactgaaa agacatttga gaactttaaa
     8041 actttaatag gagaatctta caattttgca aaacaaaaat ttaaaaagag aaaaaacaag
     8101 taaaaacgtg tgaaaataac ctctaaataa attataataa aaatattaag gttacaagat
     8161 aaaaattaat atcttaataa catgcaaaaa agcgaagcca aaaaatgtat tatttataag
     8221 gcttcgctat atctcaaata atttatttca aatttcaaaa ctatttattc tattatttct
     8281 tattatttcc tgttattcct aatctatcat tcatatcttt tatcattttt ctaaaaccac
     8341 tacctatatc atttccaaca tcttcagttc catgaactaa ttttataaag tcattttgac
     8401 cttttttcat atcttcatca gataccttat ctaatttttc tattctctta tctatatctt
     8461 ttactaatct ttccccttca gcgattaggt catcattcat tttctttaac tctgtatctt
     8521 ctgttttacc atctttttta agagatgtta caaatgattg tattttatct ctactatctt
     8581 tatatgcagc ctttacatca cttagatatt tttcatttcc tggatattct ttatctttaa
     8641 actgattatt tatactttct ggagtatcat aaatagaata tctatttaga cctgctatat
     8701 aatcattata gcttgttgaa taataattca tatatccttc attattattt acagattcat
     8761 taggattttt tcctgtattt tcacttggtt tttcattatt tttagtacat gcagttatac
     8821 ctatagctaa tactagtgct aatcctacaa ataaagttct ttttaatttc atttttatta
     8881 ccctcctaga tgttttatac tataaaaaat tttaataatt ttctttctta atttagtatt
     8941 tctatatttt tata
//
LOCUS       DAMJWC010000110         8753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMJWC010000110 DAMJWC010000000
VERSION     DAMJWC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.115"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            62..829
                     /locus_tag="PC503_003416"
     CDS             62..829
                     /locus_tag="PC503_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HDF2529368.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    1047..1260
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1514..2548
                     /locus_tag="PC503_003417"
     CDS             1514..2548
                     /locus_tag="PC503_003417"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF2529369.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2589..3806
                     /gene="argJ"
                     /locus_tag="PC503_003418"
     CDS             2589..3806
                     /gene="argJ"
                     /locus_tag="PC503_003418"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF2529370.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3821..4681
                     /gene="argB"
                     /locus_tag="PC503_003419"
     CDS             3821..4681
                     /gene="argB"
                     /locus_tag="PC503_003419"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF2529371.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            4711..5898
                     /locus_tag="PC503_003420"
     CDS             4711..5898
                     /locus_tag="PC503_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF2529372.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6007..7029
                     /gene="argF"
                     /locus_tag="PC503_003421"
     CDS             6007..7029
                     /gene="argF"
                     /locus_tag="PC503_003421"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF2529373.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7156..7773
                     /locus_tag="PC503_003422"
     CDS             7156..7773
                     /locus_tag="PC503_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF2529374.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(7993..8691)
                     /locus_tag="PC503_003423"
     CDS             complement(7993..8691)
                     /locus_tag="PC503_003423"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF2529375.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
BASE COUNT         3521 a          855 c         1576 g         2801 t
ORIGIN      
        1 taagataaaa atatatagaa tatatttaaa aattattatg caattagaaa aggagataag
       61 tatgcagatt attgatataa atataaataa tattgacaat gaacatatat gttgttcaat
      121 ttctgaaaaa aaaggagaaa attgtgtttt ttctaaaaaa gcttggatga aaaataattt
      181 tgataaaggt ctagtcttta aacgatttga tgtaagaggt aaagctttta tagaatatat
      241 tccagcagaa aatgcatggt gtcctattac tgcggacaat tatatattta ttaactgttt
      301 ttggatatct ggaaaattta agggtcaagg atattctaat ctattgctac aagagtgtgt
      361 tgatgatgca aaatcaaaag gtaaatatgg attagttgtg ctttcgtcta gtaaaaaaat
      421 gcctttttta tctgatgcta aatatctaaa atataaggac ttttgtttag cagatacatc
      481 agaaccaaat tatgagctat tatattttcc ttttactgat aatgctccta ttccatattt
      541 taagaattgt gtaaaaaaaa gaaaattaaa tgagaacggt atagttttat attacagtaa
      601 tcagtgtcca catacggaaa aatatgctcc tattttgaaa aaaattgcaa attctagagg
      661 tattgatgta aatcttataa aattcgaaac agcaaaagaa gcacaaaatg ctcctgcacc
      721 atttactaca tacagtcttt tttttaatgg tgaatttgta accaacgaga tactttctga
      781 gaaaaagatt gagaaatttt tagataccaa cattaaaaaa tttaactaaa aagagatgta
      841 aatattgtat tttgaaaata tattatttta taatttaata tattttggat gttttttaaa
      901 ttgacgaatg aaatataaaa attatatcgc aatttagata caaaatgctg gaaattaacc
      961 atatagaaaa tatttccaaa aatttaaaaa ttatattgac aaagttaaaa aaataaacta
     1021 tcatataaaa caataagaaa ataaattgaa atcctgtgaa aaagagagta gcataaagct
     1081 agttgataga gagctgggaa tggtggaagc ctagtaacga attttattgt gaatagagct
     1141 ttggaggaga ttaccagaag taatagtatg gtaattggtg aatctcgcct taagagatta
     1201 gagtgggtaa gattatctta tcaattagag tggtaacgcg ggtgtatatt cgtctcttgg
     1261 tctttgacca agaggctttt ttaattttaa atgtacattt tgtagatact ttttaatttg
     1321 agttttaatg attattgtaa ttttaccaat aagagtggta ccgcggaaaa tcgcctctta
     1381 gtatttataa tgctaagggg ttttttgttt taattagagt attttaatct acgtattatc
     1441 aaatgattat catatagtaa agtggaaaga taggatttta agactatttg aatataaaaa
     1501 tggagggaac aaaatgaata aaataaaagt tggtattatt ggtgcaactg gatatgtcgg
     1561 ggcagagttg attagattat taatgaatca tgataaagtc gaagtgacag cgataggttc
     1621 aaattcgtat gttggaaaag atatagttga tatatatcca agtataggat ataaaaataa
     1681 catgatatgt atagaaaatg aaaaagttat agatatgtgt gatgttgtat ttacagccct
     1741 tccacatgga gttagtgaaa agtttgtaat aaaggcaatt aaatcgaaaa agaaagttat
     1801 agatttaggt gctgacttta gaataaaaga tgaagaagta tatagtaaat ggtatggagt
     1861 atcttttata gataaaatct tacataaaaa agctgtatat ggattaagtg aaatatacaa
     1921 agaagatata aaagatgcag atataattgc aaatcctgga tgttatccaa ctagtatttc
     1981 tttaccattg atgccattac taagttctaa attgataaaa aataataata taataattga
     2041 ttctaaatca ggtcttacag gtgctggtag agaattatcg attagtagtc actttacgga
     2101 ggttaatgaa aatatcactg catataaaat agggaagcac agacatactc cagaaataga
     2161 acaaaattta agtgaatcct gcaaagaaaa agtaagtgta gtttttacac caaacttaat
     2221 cccagtaaat aggggaatct tatcaactat atattgtaca aaagaagata atatttctat
     2281 aaatgatata cataggaaat taactgatta ttatgaattt aaagaattta tagaaattct
     2341 tccattagat aaggtagctt ctttaaagaa tgttagattc tcaaataaat gtgtaatatc
     2401 attacatgaa aatggagata cattgataat ctgttcagct atagataata tgattaaggg
     2461 agcagcaggt caagctatac aaaacatgaa tataatattt ggtattgaag aaaatacagg
     2521 tttaaaaaat attgcaccat cattttagaa ataaaaaata ctaaactcat ataattagga
     2581 ggataaatat ggagattata aagggtggag ttacagtttc agaaggattt tttgcttcag
     2641 ggattcactg tggcttgaga aaaaataaag aaaaaagaga tttagctttg gtttattcag
     2701 atgttttatg tgatgcagca gcagtagtaa ctcaaaataa agtaaagggc aatcctgttt
     2761 atgttacaca ggaacacatt aaaaatggaa aagcacaagc tatcatagta aatagtgcta
     2821 atgctaatac ctttaatgga aaagaaggac ttataaatgc ttataaaatg gctaaattca
     2881 ccagtgataa attaaatatt aaagaaagtg atgttttggt tgcatctaca ggtgttatag
     2941 gaaagccatt aaatatagat ttaatagaag aaaatatgga tgaattagtg aataatctaa
     3001 gtaaacaagg tcatattgga gcaagagaag ctattatgac aactgatatt ataaaaaaag
     3061 aaatagcagt agcaataatg tatggagata aaaaaataac tattggaggt atggcaaaag
     3121 gttctggcat gatacatcct aatatggcaa caacgttagg atttataact acagatgcaa
     3181 atattgatgg agttttgcta aaagaagctt taaaaattgc tgttgacaaa agttttaata
     3241 gagttagtgt agatggagat acaagtacta atgatatggt aatgattcta gcaaatggaa
     3301 aagcaaaaaa tgatagaata aacaaaaaag atgaacatta tcaagtattt ttgagtgcac
     3361 ttacatatgt ctgtatagaa cttgctaaac ttgttgcaaa agatggagaa ggatgtacaa
     3421 aactaattga atgctatata aatggagcat taagtgaaga acatgcagta aaattagcaa
     3481 aaacagttat atcttcttca ttagtaaaga cagctgtatt tggagctgac gcaaattggg
     3541 gtagaatact gtgtgcttta ggttatgcag gtgaagaaat agatatggaa aaagttgata
     3601 ttatttttga gagtatgaaa ggatatattg aagtatgtaa aaatggaaat ggattagatt
     3661 ttaatgagga aaaagcaaaa aaaatccttg aagatgacga aataagtata ttagtagatt
     3721 taaatatggg caatgccaga ggaaatgcat ggggatgtga tttaagctat gattatgtaa
     3781 gaataaatgg aagttataga aattaggagg atatacttta atgattaata tagaaaaagc
     3841 aaatacactt atagaagctt taccatatat agaaaaacat cagggaaaga ctattgtagt
     3901 taagtatggt ggaagtgcaa tgaaaaaaga tggtctaaaa gaatctgtta tggaagacct
     3961 tgtgttaatg agttatgttg gaatcaatat agttttagta catggtggag gggcagaaat
     4021 caataagatg ctagcaaaag tggatataga aagtaaattt gtaaatggtc ttagatatac
     4081 agatgaagag accatggaaa ttgtaaaaat ggtacttgct ggaaaggtta ataaagactt
     4141 agtaaataaa atacatacaa aaggtggaaa agcagtaggg ctttgtggaa tagataataa
     4201 tatgatttta tgtgacccat ataaaaatta tgaacttgga tttgtaggag aaatcaaaaa
     4261 agtaaatgtt gagcttatag aatcttgtct aaagtcaggt tatatttcag taattgcaac
     4321 tataggtgtt ggagatgatg gagagactta taatataaat ggtgacacag cagcttctgc
     4381 tatagctaaa gagttaaatg cagataaatt gatacttctt acagatgtcc ctggtttgtt
     4441 aagagagcca gatgaagaaa aatcattaat aacagaagtt atattagagg atgttgataa
     4501 attatttgaa gaaggtataa ttactggagg tatgatacct aaaatagagg gatgcgtaga
     4561 tgccttaaat aacggagtaa atagggtaca tattttggat ggaagagttc cacattctat
     4621 aataacagag ctatttactg atagtggaat aggtacatta ataagaaaag aaactgaata
     4681 aaattataag tttaagaggg gagaataaga atgaataacg acaatacaat ttcaaaatgg
     4741 aatgaatatt ttatagatac atataaccaa cccaattttg tcatagatta tggtgaagga
     4801 agttgttttt ttgatactaa tggcaataaa tatatagatt ttacaagtgg atatggagta
     4861 tcttctcttg ggtatagtaa tagtaattta aagaatgctc taaaagagca agtagataaa
     4921 ttattacata cttcaaattt atattttaat gagccagtgt tgtattcagg agagaaaata
     4981 attaattcaa gtggaatggc taaagtatat ttttgtaatt ctggaacaga agcaaatgaa
     5041 acagcattca aaatagcaag aaagtatagt agtgacaaat atggtaatgg tagaggaact
     5101 atcataagtt taaaagactc ttttcatggt agaacaatga tgtctttaat ggcaactggt
     5161 atggacaaat accataagta tttttatcct cttcccgaag gttttaaata tatagaaaga
     5221 aataatattg aagatttaaa aaataatctt gattccacag tttgtgcaat aattcttgaa
     5281 gcgattcaag gcgaaggtgg agttaatgtt cttgaaaaag attatgtttt ggaaatagta
     5341 aaaatatgtc aagaaaagga tattgtagtg atttttgatg aagtccaatg cggtatagga
     5401 agaactggta aactttttgg ctatgaatat tttgatgtaa aaccagatat agttaccgta
     5461 gcaaaagggt tgggagcagg aataccagta ggaggagtat tggtaaataa aaaactttca
     5521 aaagtactag gaaaaggaga ccaaggtaca acttttggag gtaatttatt agctatggtg
     5581 gcagcttcag ttgtattaga tgagatatct aaagatggct tttataatga agtattagaa
     5641 aaaggaaatt atataagaaa atctattgaa agttttaata acaaagttat attaaagaca
     5701 aaaggtattg gtctaatgat aggaattgaa actaatattg aatctagtat tatagaagag
     5761 aaagctagaa aaaaaggatt gcttattttg actgctggaa aaaatgtatt gagattttta
     5821 ccaccattaa caatcagtta taaggaaata gatgaggctc ttgaaatcct aaaagatata
     5881 ttactagaaa ttaactaaat attcaaaaaa tagttgatta aagataaaaa ttagaagtaa
     5941 ataaaaaagt aaagtgctaa caagtttaat tgaatttaaa aagtttataa gaaggggcga
     6001 attaatatga ataatataag tttaaaaggt aagagttttt tgacattaaa ggattttaca
     6061 aaagaagaga ttagatattt attaacttta tcaagttatt taaaaactaa gaaaaaagtt
     6121 ggtataaaag gcgatttgct acaaggaaaa aatatagctt tattatttga gaaaacatca
     6181 acaagaacta gatgttcatt tgaagtagca gctcatgatg aaggagcaca tgtaacttat
     6241 ctaggtccaa atgattgtca tatgggtaaa aaagagtctg tatcagatac agcaaaagtt
     6301 ctaggaagat tctatgatgg aatagaattt agaggcttta aacaagaaac agttgaaagt
     6361 ctagcaaaat attctggtgt acctgtttgg aatggactta cagatgaata tcatccaaca
     6421 caaatactgg cagatttttt aacagtaatt gaaaatgtag ataaagattt gaataaagtt
     6481 aaatttgtat atgttggtga tgctagaaat aatatgggga actcactgat gataggatgt
     6541 gctaaaatgg gaatacattt cgtagcacta gcacctaagg aactttggcc aaatgaagaa
     6601 ttggttaagg aaatgaagga aatagccaag aaatccaaag gagatataat gttgactgaa
     6661 aatattgatg atgttaaagg tgcagatgtt atatatacag atgtatgggt ttctatggga
     6721 gaagaggagc aatatgaagc aagaataaat caacttaaag attatcaagt aaatatggat
     6781 atgataaaga aaactgaaaa tgaaaatgtt atatttttac actgtcttcc agcatttcat
     6841 gatttagaaa ctaaggttgc tcaggagatt tatgaaaagt tcggattatc agaattagag
     6901 gttacaaacg aggtatttaa ttcaaaatat tcaaaggtat ttgaagaagc tgaaaataga
     6961 atgcatacaa taaaagctgt tatggtttct actatgactg atgtaaatat gaacaataat
     7021 ttaatataga tatgttttaa tatagacttt actttaatga aaatttataa aatattttaa
     7081 atatattatt caaaaactct cattatatgt taaaataact tatgtatcaa caaattaaga
     7141 gggaggattt gagatatgaa aaaaatcata ttagctttaa caactttttt attagcaata
     7201 tctttaacag catgttcaag tgcaaaacca gaagatacaa ttgatagttt ttttaacagt
     7261 gcgaaaaagt ttgactttga aggcatgaat aaggtaatgg aaaataatga cgaaaaatat
     7321 aaggatatat taaaggaatt agatacaaaa gacccaaatg cccaatatgt tttagattat
     7381 ctaaaacaga atgcatctaa aatcacatat acaataaaag acagcgaggt taaaggtgat
     7441 aaggctacaa tcaaagtaga atgtaaattt atagattcaa caccattact tcaagaaata
     7501 gtagctgagg catttacaaa gatgattggt atgagttttt caggacaaga cttaactgat
     7561 gagaaaacaa ctgaaatgtt agtatcaatt atgaaagaaa aacaaaaaag cgttaaagag
     7621 acttatgtta caaaaaatgt agagtttgaa tgttctaaaa aggataataa atggataata
     7681 agttcagtaa atgatgcagt agctgatgta ttgttatcta atcttgttac agcaggacaa
     7741 gaattttcta actctatgaa tacacttgaa taatattgtt taggtgtagt aaagtaataa
     7801 atatatgatt atttttataa ataaacatat aaatatttat gaaggatacc atttttggta
     7861 tcctttttat taatataatg aaatacatgg ttaatttcta tattgtcaag aaactatgat
     7921 atatgttata agtctatact atttaaaata aacttataac atatattttt tataatatag
     7981 tgtatgaaaa atttatttaa ctaattttag atatttattg acaactgatt cagccaagca
     8041 ttttgatgaa tcaacaatat ttattgaagg atatgatttt tctaaaacta catttaaatc
     8101 agtacaagca attactatat tttctataga ttcattttta acatcttcaa taagtttatt
     8161 ccaaatatca atattgtgtg gattttcttt atccattttt atattttgaa taagattgtt
     8221 taattttatt tgccattcat ctttaaatat aaattcatgt ccattatgta ttataccatt
     8281 ctggtaaatt gtagactcaa aagttgaact agtcgaaaaa agagttactt tttgtgagat
     8341 agtaggtaat tttttaactg tttcttctac aatatttaat attggtatat taatagactc
     8401 ttttaattct ttaaagtata tatgtgctga attgcatggc attgcaataa aatttacacc
     8461 agttgattca agcttttgta atccatcaat tatagtttct ttcataaggt catgatttat
     8521 tggacggtca atataaaatg gggtaggtaa tgaatatatc atcatctttg gaaattcatc
     8581 atcatatttt gctccatatt gagattgaca ctcatcaata attaaatcaa caaaaggggc
     8641 tgttgacctt ggacccattc cagccaaaat accaattaat ttttcattca taaaaattat
     8701 ctcctttata tataaatata tttatgtata aaataaaaat ctataaaagc ata
//
LOCUS       DAMJWC010000111         8726 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMJWC010000111 DAMJWC010000000
VERSION     DAMJWC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.116"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            129..896
                     /locus_tag="PC503_003424"
     CDS             129..896
                     /locus_tag="PC503_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2529376.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            1179..1376
                     /locus_tag="PC503_003425"
     CDS             1179..1376
                     /locus_tag="PC503_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2529377.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            1405..2481
                     /gene="vorB"
                     /locus_tag="PC503_003426"
     CDS             1405..2481
                     /gene="vorB"
                     /locus_tag="PC503_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2529378.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            2484..3203
                     /locus_tag="PC503_003427"
     CDS             2484..3203
                     /locus_tag="PC503_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2529379.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            3216..3755
                     /locus_tag="PC503_003428"
     CDS             3216..3755
                     /locus_tag="PC503_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2529380.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            3912..4970
                     /gene="buk"
                     /locus_tag="PC503_003429"
     CDS             3912..4970
                     /gene="buk"
                     /locus_tag="PC503_003429"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2529381.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            4988..5881
                     /locus_tag="PC503_003430"
     CDS             4988..5881
                     /locus_tag="PC503_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2529382.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            5911..7119
                     /locus_tag="PC503_003431"
     CDS             5911..7119
                     /locus_tag="PC503_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2529383.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            7143..8402
                     /locus_tag="PC503_003432"
     CDS             7143..8402
                     /locus_tag="PC503_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2529384.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT         3391 a          966 c         1737 g         2632 t
ORIGIN      
        1 aaattaagta taatattttt gttttataaa atataattaa gataaataga taattttgta
       61 attttaatat ataatattta gtagagtgtg ggagtagcac ttaatatttg aaggaggagt
      121 ttttgtatat gggagaaata ataaatgcat tagatagagc cctagacata attttgctgt
      181 tatatcatga aaagagagaa atgggaataa ctgaaataag caaggctatg ggagtatata
      241 aaagtactgt acatagaact ttggttactc ttgaaaacaa aggttttgtt atacaaaatg
      301 cagagaatgg taagtattgg ctaggaataa atttatatgc aataggtatg gttgtgggag
      361 aaaaaatgtc attgactgaa atagtaaaac catatacgaa aaaattaaat caagaattta
      421 acgaagtagt taatgtatct atattagaag aaagagctca agattctcca agaagtatca
      481 taatacataa agagtatggt tcaaatcaat tactttcagt aaatccatcc gttggttcaa
      541 gtagtgaatg ttattgttca gcagttggta aatgtcttat ggcatttaat gattctatag
      601 attttgaaaa atatagaaaa acaccaatac acaagtatac agaacataca attgataatt
      661 gggatgatat gatgcttttt ttagcaaaaa taaaagaaca aggatatgct atagatgatg
      721 aagaactaga acatggacta acttgtattg gagcacctat cttagataaa aataataaag
      781 ctattgcagc cataagtttg tcaggtccaa ctataagaat gagagaaggg gactttgagt
      841 ataagattaa aagagttata gaaactgcaa aaagtatatc tgaacttttt agatgatttt
      901 taatctcgat aataaaaata ggctatattt aaattgttat ttgtaaatat cagtttaaat
      961 gtagcctatt tttctttaat ctaaaattaa atattcttaa aatttaaaat gttattgaaa
     1021 tatataagcg aatgtgttat cttttaatta agcaataaaa atagaacaag gttctatact
     1081 atagaacaaa attgatgcat atatagtatt tatacaaaat ataaatatta tatatttaaa
     1141 attaagtaaa aatattacat aaaggggaga tttgagaaat ggaaaaagtc aagttgagtg
     1201 ttgaaagatg taagggatgc tatctttgta ttgaagcttg taaaaaagat gcaataagtc
     1261 tttctgacta cacaaataaa aaaggctttg taactattaa agtcgatgaa gaaaaatgta
     1321 ttcaatgtgg cgcttgttat acaatgtgcc ctgatttagt atttgagata ttataaatta
     1381 tttttattag aggggagaaa aggtatgcaa agtttattaa ttaaaggaaa tgaagcttta
     1441 gcagaaggtg ctatacgtgg tggctgcaga ttttatgcag gttatccaat aacgccacaa
     1501 tcagaaatat tagaaatgat ggcatggaga caaaaagaag ttggaggagt atttatccaa
     1561 ggtgaatcag aaatagccag tgtaaatatg gttatgggag caagtgcact tggagcaaga
     1621 gctatgactt cttcatctgg tccaggattt tcattaaaac aagaaggtat tgcatattgg
     1681 gtatcagctg gtttgccagc agttgtagca tgtgtgcaaa gatatggtat aggtgatgga
     1741 tttataggag ctggtcaaga taattattgg caagcagtaa aaggcggtgg aaatggagat
     1801 tatcatttaa tcgtgttagc acctaatagt gttcaagaaa atatggatat ggcatatgaa
     1861 tcttttgaat tggctgaaaa atatatgcat ccagtactta tactttctga tgctacaata
     1921 ggtcaaatgg tagaaccttg tatagcacca ccaatgaaag aatacgatat ggataaagct
     1981 ccatgggctg caaaaggaac acctgtagga gaaaaaaata aagtaataac tgatataaca
     2041 tattttgaag accaagatac atggcaaaaa gggtatatag aaaaaatgag aaaagttcaa
     2101 gaagatgaac aaagatggga agagatagaa atagaagatg ctgaagtggt atttgtggca
     2161 tacggtattt catcaagaat agcagaaggt gcagttagag atgctagagc aaaaggaatg
     2221 aaattaggtc taataagacc aaaaacattg tggccttacc caagaaaagc atttaagaaa
     2281 ttaagtgatt cattgaaggg acttgtaaca gttgaaatga acatgatggc acagatgaag
     2341 gaagatgtaa ttatagcatg tgataataga tttccagtat attcagtagc aacagctcaa
     2401 tatatggcag aagtaaatca attaatagat tttgctcaac agattataga tggaaaagct
     2461 aagcaagagg aggtatttta attatggcta aaaaagcacc agcaataatg atgtgtgaaa
     2521 atatgttctg tggaggctgt ggacactcta tagtcgatag aattattgga gaagtattaa
     2581 cagaaatgga tatatgtcaa gatacaatta tatgttcaga tataggttgt aatcatatgt
     2641 ttcaatttag tatgaatgta gatgttgtcg ttccacctca tggtaaaatg ggagcagcaa
     2701 tggcagctat gaaaagagtt agaccagata aatatatatt tacaatagct ggagatggtg
     2761 gagcttatgc aatagggctt ggagaaacta tgtcagctgc tactagaaat gataatgtaa
     2821 tatttcttgt tatgaacaat aatatgtttg caatgacagg agggcaaatg gctccaacta
     2881 ctatagaagg tcaatataca gcttctactc cagcgggtag aaattacgca gatcatggtt
     2941 caacatttga tgttgtaaaa gttatgggaa atttagatat agcatatcta gcaagaggaa
     3001 caataactaa ccctaaagaa ataaatacaa caaaaagata catcaaaaaa gctctagaaa
     3061 aacaaaaaga aaagaaaggt ttttgcttaa tagaagtgct tgtaccatgt ccaacaaact
     3121 ggggattaaa gccagtagat gctatgaaga gaattgaaaa tgaacttgtt ccaaagtatc
     3181 cacttggaga atttattgat tagggaggaa ataatatgtt gaatgaaatt atatgtgctg
     3241 gttttggagg acagggagtt cttacagcag gaaaaattat aatgtatgtt gcatataagg
     3301 cagaaaagaa aattacatgg ttcccatctt atggaaatga gatgagggga ggaagtgcaa
     3361 attgcaatgt tgttgtaagt gatgaaaaaa ttgcaaatcc ttgtgtaaaa aatccagata
     3421 tactattggg aatgaacagc gtatcagtag ataagtatga aagtttaatg aaaaaaaatg
     3481 gttatatgtt tgtcaatgaa tcactagtaa gtaaggatag aaagtacaga gaagacatta
     3541 atgttataaa agtacctgtt actgaaatag cacaaaattt aggcaatgaa aaagctgcta
     3601 acatttgcat gttaggtgct atggtaaaga gtttggattt atttacaaaa gaagaatttg
     3661 aaagtggtat gtgtgaatac tttgaaaatc aaggcaaagg taaattcaat tctaaaaatg
     3721 tagaagcatt tgaagctgga tacgactacg aatgaatatt ttaaatattt aaaataatta
     3781 ttgaaatact tatttttata tgttagtatt taattaataa aatatagaac gtcgttctgg
     3841 acaatgggac gaagtcttta ggtcggaata caagaacggc gttctgtata atagaactag
     3901 ggggtgttaa attgaaagtt ttagtaataa atcctggtgg tacatccaca aaaatttctg
     3961 ttttccaaga tgaaaatgaa attttgaaaa aaaatataac ccatacaaga gaagatttaa
     4021 aaaatttttc taaagtattt gatgaatatg attatagaaa acaactgata gtagatattt
     4081 taagtagtga gaatcatagt ataaattctt ttgacgcagt agttggtcgt ggtggactta
     4141 tgaaggctat aaaaggtggt acctatactg tgagtgaaga aatgattgag gatatgagaa
     4201 atgaaataaa tggggaacat gcatcaaatt taggtgcatt attagctaaa actatagctg
     4261 atgaaatagg agtacaatca tttgtagtag acccagtttc tgtagatgaa tttgatgatg
     4321 tatcgaggat tacaggaata tcagacatag aaaaagcaag ttggttacat gcattaaacc
     4381 ataaagctgt ttcaagaaaa attgcacaaa aactaggggg aaaatacgag gattataact
     4441 ttattgtagc tcatttaggt tcaggaatat cgattgtagc acataaacaa ggcaaaatga
     4501 ttgatggaag tggtggtagg tctgatggtc cattttctcc agaaaggagt ggtggattac
     4561 ttgcatatcc tcttatagaa ttgtgttact ccggaaaata tactcatgat gaaatggtcg
     4621 caaaagtaag ttcgattggg ggaatgtacg attatttagg aacaaaggac atgatagaaa
     4681 ttgaaaacag aatcaaggag ggtgatgaaa aggcaaaact tataatggat gcatttattt
     4741 atcaagtagc aaaagaaatt tctatgtatg gagcttcact ttcagggaat gtagatagag
     4801 ttatcttgac aggagggata tctcactcag aaatggtagt caaaggagta gcagaaaaag
     4861 tttcatatct agctccaata gagatagtac caggagagat ggaaatggag gcacttgctc
     4921 taggggcact tagagtactt aatggagaag aaatagcaaa aacttattaa tatttaggag
     4981 aaagagtatg ttaaaagatt ttaataattt attagaagag gctaaaaagc ttgaacctgt
     5041 tattgtaagt gttgctgttg cagaagacaa agaagtatta aaggctgtga aatcagcaac
     5101 agatttaaac attataaagc caattcttgt aggagacaag gataaaatag aaagtatatc
     5161 aagagaaatt ggattaaaag gtcatgaaat aataggttgt caaaatcccg atgaatcagt
     5221 taaaaaagct gtagagatag ttaaaaataa ggaagctaaa gttcttatga agggattagt
     5281 aaatacaagt gtctatatga gagctatatt aaataaagaa acgggtctta gaacaggaag
     5341 attattaagt ttgcttgcag tatatgaatt acctcaatat cataaacttc tttattgtac
     5401 tgatagtgga ataaatgtat cgccaaactt aaatcaaaaa aaagatataa tgacaaatgc
     5461 acttcttact atgaaaagta taggcatgga aaatcctaaa actgcgatac ttactgcaaa
     5521 tgaaatggta gaccctaaga tacaatctac agtggatgcc aacctacttg tagagatgga
     5581 aaaatcggga gaaataccaa agtgtatagt ggaaggtcca atagcatttg atgtagcatt
     5641 tgatgcacat gcagcagaac ataaaggtat taaaagtaat attgctggtg atgttgattt
     5701 attagtattt ccaaatatag aagcagggaa tatattagga aagtcatggc ttagatttaa
     5761 taaagctaag tgggcaggta tagttttagg agcaacaaat ccgataattt taggttcacg
     5821 ttctgacaca gctgaaataa aaataaattc aatagcatta gcgtgcctag catcacaata
     5881 agaaattatt attaaggagg aaaaagtatt atgaaatatg caaaaagaat ggatatggta
     5941 aaagcttcag ctataagaga ttctcaaaag aaaatagctc agaaggtagc aagtggtgga
     6001 actgttatat cttttgctgc agggcttcct gacccaaatt tatttccaat agaagagata
     6061 agtgaaataa ctcaaaaagt acttaatgaa aggggaaaat ttgccctagc atatggacct
     6121 actaaaggtg aagatgagtt gttagatcta ttagtaaaaa gaatgaaaga agaagaaaat
     6181 attgatacaa aagcagaaaa tattataata actactgggt cacaacaagg gatagcatta
     6241 agtgctatga ttttattaga aaagggagat gtagtagtta cagaaaatcc aagttactta
     6301 ggtgcaataa atgcatttag accttatgaa tgtgattttt taggagtaga tacagatgaa
     6361 gaaggaatgg taacagatga tttagacaaa ttattatctg aaaattctaa cataaaggtg
     6421 atatatgtaa taccaacatt tcaaaaccct acaggaaaaa catggtcttt acaaagaaga
     6481 aaagatttta tggaagtcgt gaataaatat gatgtcatag taatagagga taatccttat
     6541 ggagaaataa gatttacacc agaacctcta cctacactta aatctcttga tactaaagat
     6601 aaagtattgt accttgggtc attttcaaag gtattatgtc caggatttag agttgcttgg
     6661 atgtgtggta atgtagacat catagataag gcagaacttt taaaacaagg tatagattta
     6721 cagtcaaatc aattttcgca agtacaagta atagaatttt taaagaaata caacttaaat
     6781 gaacatatag aaaaaataag agcagagtat aagaaaagat gtctgctaat gttagatgct
     6841 atgaagaaac atttcccaga ggaagctaaa tatacagaac cagatggagg aatgtttata
     6901 tgggttgaac ttcctgaaag tataaatgta gatgatttat tagataaagc cattgatgct
     6961 ggagttgctt atgtttctgg agagtccttc tttgcaaata atggtccaaa aaatactatg
     7021 agacttaact atacaacaat gtcagaagaa caaatcgtta aaggtgttga gatacttgca
     7081 gaagttataa aaaaagaact caattatgct tgtgaataaa tataaaaagt gagggtttaa
     7141 atatgggaga aaaagaaaac ggtataaagt ttggaaagtt aatgtttcaa cttgttatta
     7201 tagcaatatc ttgggaatta gtttatatta taccatttat ccaatataca ttatatgatc
     7261 caatcctaaa agcattagaa tgtacaaaca ctcaactagg ttttctactt acaatttatg
     7321 ggttaggtaa tatatttgga gctcctatag gaggctggtt agcagataga tttgattata
     7381 gaaagataat tttaggttct gtatttctta atggagtagt atcattttta tttgcattta
     7441 atatgaacta tccatttgca gttgctactt gggtaggttg tgcaatcaca tcattagtta
     7501 tgaactatcc ttctatggta aaaatactta gagttatagg aaaagataat caaggtaagg
     7561 tttatggatt taatgaagct atggttggag tttctggagt agtaatggga gcaatattct
     7621 tatatattta tacatgcttt gcaactccta cattgggtat gagatgggta atgatatctt
     7681 taggaatatt atcaatagca atgtgtccag tattatggtt tgtaattaaa gatgtagata
     7741 ttaaagaaga aagagaagaa gcaggtgaaa aaatgtctgc tggtgatttt ataacagtac
     7801 taaaatcacc aaatacttgg ctagtaggaa taagtatatt ctgtgtatat tcattcacag
     7861 ttacaatgtc ttattttaca ccatatataa catctgtact tggaggttct gtagcattat
     7921 ctggtgcatt agcaataata agacagcatg gtctaaaatt atttggagca ccatttggag
     7981 gatattgtgc agacaaatta aaatctccta caaaagtact tttaccaata tatgtatttg
     8041 gtatagcagt aatagtttta ttcctagtat tacctgcatc aactccaatg actatattca
     8101 tagctttaac atttgtagta ggtatattag gttacatggg aaaaggtata tattatgcag
     8161 tacaagatga agtaaaagtt ccagttaaat attcagcaac tactataggt atagctgcag
     8221 ctttaggatt ttcaccagat gtattccaat ttgcattaat aggacactgg atagatactt
     8281 atggcaataa aggttacaca tatacattta tattccaaat agcaattcta gttattggaa
     8341 tactatcttg tttatatata ttaaaggtta aaaagagaag agcaagtaaa ttagaagctt
     8401 aaatattcaa tttggtaatt aagtatatat aaatacaata cttattttga tgaatgtgat
     8461 tgtataaata acataaaaaa tatcaataga ttaagtttta taataatgtt tagagaataa
     8521 agtataaaaa tcaaaatgtt atcaagtttt ctaggtttta acataaagtt acccctgaag
     8581 gtgtaaaatt gagtggcaat tattatctat tttcttacct acataaacct atttaattta
     8641 aattctaaga gattttcaaa atagatggta gttgtactca attttaaacc tcataataaa
     8701 tacgaaaatt taaaatctaa ctagat
//
LOCUS       DAMJWC010000112         8502 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMJWC010000112 DAMJWC010000000
VERSION     DAMJWC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8502
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.117"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            247..1233
                     /locus_tag="PC503_003433"
     CDS             247..1233
                     /locus_tag="PC503_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2529385.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1402..1550
                     /locus_tag="PC503_003434"
                     /pseudo
     CDS             1402..1550
                     /locus_tag="PC503_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1569..3050
                     /locus_tag="PC503_003435"
     CDS             1569..3050
                     /locus_tag="PC503_003435"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF2529386.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3076..4047
                     /locus_tag="PC503_003436"
     CDS             3076..4047
                     /locus_tag="PC503_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF2529387.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4303..4905)
                     /locus_tag="PC503_003437"
     CDS             complement(4303..4905)
                     /locus_tag="PC503_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2529388.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPTLWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            5186..6397
                     /locus_tag="PC503_003438"
     CDS             5186..6397
                     /locus_tag="PC503_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF2529389.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKYNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6465..6662
                     /locus_tag="PC503_003439"
     CDS             6465..6662
                     /locus_tag="PC503_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF2529390.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILSLYIKQLGVTDVSLI
                     QQYSGIVFGCTFVVAAFFSPI"
     gene            6696..7667
                     /locus_tag="PC503_003440"
     CDS             6696..7667
                     /locus_tag="PC503_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2529391.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7854..8231
                     /locus_tag="PC503_003441"
     CDS             7854..8231
                     /locus_tag="PC503_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2529392.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3461 a          886 c         1358 g         2797 t
ORIGIN      
        1 agccttattt ttatattata aataaattag agtatttatc aattcatagt agataaaatt
       61 gaaattaaat ataacaacaa aaaatgaaaa ttacaattaa tttaatgtta aagactcaat
      121 tatttggatg tggaatggat agtacaagta gtatataaaa agtattgact ggacaaataa
      181 ctatatttta ttttaaatat ataatataat gtaataaaat atatcaaatg tagaaggtga
      241 taacctatga aaaaaataac aataaatgat attgctaact tggcaggagt atctaaaagt
      301 actgtatcaa gatatctaaa taataaagat atcagtgatt ctactaaaga gaaaataaag
      361 acaataatag atgaatatgg atatgagccg aatgcatttg ctcaaagttt gagagctaaa
      421 aaaacatact ttattggtat tataacaccg tgtttagatt cttttgtaaa atctaaaatt
      481 atgatggcaa tagatgaaga actcaaagaa ttaaaatata catcactaat tattaatact
      541 aatagaaaaa taaggtcaga aatagatagt atatcaaaat tagctagtct aaaagttgat
      601 ggaataatac taattggtac cgaaataact aaagaacata agaatgaaat tgaaaagtta
      661 gatataccga tagttgtagt tggacaaaaa gttgatggta tcaatagcat agtgaatgat
      721 gattatggag caggatataa aatgggtcaa tatattgcta ataaaggtta caaaaacatt
      781 gtatatttag gtgttgatga aagtgatata tcagttggtt taaatagaaa aaatggagta
      841 cttaatgggt taaaagataa agggtatgat gcaaaagtat tttatactga ctttgaccaa
      901 gaaacgtcta tacaaagaag tggagaaatg ctagaaagtg aaaatccaga tataataata
      961 tgtgcaactg ataatatagc aatagcaaca atgaaagaaa tcaataagag aggtaaaaat
     1021 ataccacaag atatatctgt agctggattt gggggatatg atgtattgtc tattataagc
     1081 cctaaactta caacaataaa gtttgaaaat aaaaatgcag gtaaagtagc agcaaatacg
     1141 atagtaaatt taatacaaga aagaaaagaa ccactattaa aggagattaa atttgaatta
     1201 atagaaggtg aaagtacaat aaataaaaat taagatacac attacatata ttagtaatgt
     1261 gtattttttt actaaaaaaa ctataattct aaaaattagg aaaacttttt tgaaagaaat
     1321 attgcatctg aaataaattt atgctaatct ttaattaaac cggtttcgaa accggtttaa
     1381 ttaaaccgat agaatagcaa aatgagtgca aaaataactg attgtaacaa agtatcaaag
     1441 taattattag agtacatagg aataaacaaa atataaaaga tgtagcacat tgtgtaataa
     1501 gactaagaat tgttttagat agcaataata aagcaaatat aaaattataa aagaaaagga
     1561 ataaaaatat gtacaaagag cctaaatata gaaccatatt agaatcgaca aaagaagaat
     1621 taaataaatt aagaaatata tctttaaatg ataaatataa accactattt catatacatc
     1681 cacaacatgg actacttaat gacccaaatg gattagcata ttataatggt aagtatcatg
     1741 tattttatca atggtatcca tatgatgcaa ctcatggaat gaagcattgg gcttatgtaa
     1801 gttctgatga ttttgtaaac tggaatagag aagatgtagc attaatacca atcgaaagtt
     1861 atgaatctca tggagcatat tcaggtaatg cgatagaggt agatggaaaa ttgcatatgt
     1921 attatacagg gaatataaaa tatagtgcag aagatagata tgcatatcaa aacttagcta
     1981 taatgaacaa ggatggtaaa ataactaaat atgaaaataa tccaatagta agtgaaatac
     2041 caaaaggata tacaggacat gtaagagacc caaaagtatt taaaagaaag gataaatact
     2101 ttatgttact tggagcacaa acaagtgata aaaaaggagc tataatagta tatgaatcta
     2161 aaaactctat agattggaat tttaaaggag aattaaatgt aaaaaatata gatgaagatt
     2221 ttggttacat gtgggaatgt ccagattata ttaatataga tgaaaaagat atattaatat
     2281 tttcaccaca aggagtagaa cctaaaggat ttgattatca aaatatatat aatgtagtat
     2341 atgctattgg taatatggat ttagataatt taacatttga aatagataca atgaaagaac
     2401 tggaaaaagg atttgatttc tatgctccac aaacatttat aaaggactca caaataatac
     2461 tatttgcatg ggctggaatg ggagaagttt tataccctac agataaaaac aaatgggcac
     2521 attgtctaac tgttccaaga aaattaaata taaaaaataa taagctattg caaatgccag
     2581 tagatgaatt aattaaatta agatatgatg aaacaagtgg gcaaaatact ataaagaata
     2641 atattaatat tatagaaaat gatgaaaatg tatatgagct taatattaat ataaaaaata
     2701 ttgacagcaa taaatttggg ctggaattat tttcatcaca agatgaaggt gtaaaattag
     2761 aatttaacaa attaggaaac attgtaactt tagacagaag caactttaaa aaagttttcg
     2821 gtgttgaata tggaacaaat agaaaagaat atataaatat tgatgaaaat actaatatca
     2881 aagtactagc ggatagaagt attttagaaa tttttataaa tgaaggagaa gtagtattta
     2941 ctagtagaat atttgctaaa gaaaattcta atcaaataag ggtttatagt gataaaatag
     3001 tagagtatga gtatactaaa tttaaattaa agcaaggtat tgaattataa aaacacatta
     3061 taaggggtag aaaagatgaa aaaagtaatt agcataggag aagctttaat agactttata
     3121 ccgaatcaaa atggtggtaa attaaaaaat gtatcagaat ttagaagagt agcaggagga
     3181 gctccagcaa atgttagtgc tgttgtagca aagcttggag gaaaatcgag ttttatatct
     3241 aagttaggaa aagatgcatt tggtgattat ataatagatg tattaaatga agtaaatgta
     3301 aatactgatt atgtattgag aacaagtaaa gcaaatacag gacttgcttt tgtatcatta
     3361 aaagaagatg gtaatcgtga tttctcattt tatagaaatc caagtgcaga tatgctttta
     3421 gaagctgatg aagttaaaaa agagtggttt aataattgtc atatcctaca tttttgttca
     3481 gtagatttaa tagatagtcc aatgaaatta gcacataaaa aagcaataga atacgcactt
     3541 gaaagtaata gtataataag ctttgaccct aatataagat tacctttatg ggatagtgag
     3601 caatcttgta aaaaggcaat atcagaattt ttaccttttg ctcatattgt taagatatct
     3661 gatgaagaat tagaatttat aacaggagaa aatgatatag aaaaatcatt acataaactc
     3721 tttgtgggga atgttgaact agtattatat acaaaaggaa aagatggagt agatgcatac
     3781 actaaaaaag taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga tacaaccgga
     3841 gcaggagatt cttatatagg ttcattttta tacaccttat tgtataaaca aataacattg
     3901 aatgatataa aagaaatgaa acaagaaacg ttaaatgagt atttagaatt ttctaattat
     3961 tatgcagctc gtagtacaac tattaaaggt gcgataagtt catatgcaac aaaggaagaa
     4021 ataactgaat ttataaaaaa tttatagtag gaatgagtaa taggttttga aggaagtaac
     4081 atgtaaagag tttttaagga tgtttactat gaaaataatt aacatataaa aagcaataaa
     4141 gaggctgtct caaaatagag ataagcctct ttatcattgt tgaaatgata aaaaatattt
     4201 taattattgt tactttttag aagaatatat atcttatttt aaataagcaa attatgtaag
     4261 atttatttat attatcaata ctttacttgg agtattatgt ctttagcagt tatctacttc
     4321 aattgaatta tctaaaatat aataaatttg ttttgcaaat tgacgagaat gttcttcttt
     4381 ttctttattc ataaaattag gtttacctaa atcacgttca acaagcattc ctatatattt
     4441 taactgtgaa tgcttacagt agcgcttcat accattttcc caaatatcag cacccttttc
     4501 aggtctatat ccacatgttg taataagtgc tactggtttt cctgcccata gagtggggcc
     4561 tttctcatta ccatagtatt tattcattcc atacaccaat ctatcaagta gtgctttcat
     4621 tggagaagtg cagtaccaag aataaattgg agtagcaaaa acaattaaat cacacataag
     4681 aattttcttg aaaattttct gaacatcatc tttacaataa catccaaaat caaataagtt
     4741 atcctgacat tttttacaag caatacatgg ctctatttta caatcatata accatattac
     4801 ttcaatattt gaattataat tttctaattc ctcaataaaa ggttttaaaa tagcagcagt
     4861 attacctttt ttcttaggac ttcccataag aatgcatact tccatattga tacctccaca
     4921 gtattttaaa atagttttta gtgcttaata tagttttagg atactatgag aatacgttaa
     4981 caacaataca ctttgtatat ttgtaataaa attgaaacaa attgttttat caataaaagt
     5041 tggaatgtat ctataattaa aaatatttta ggtatgtttt tacatatatg tgtgtagtta
     5101 actatggtaa tttattgtaa aattatctta taggattata attgcttaat ttatgattat
     5161 atttaaaatc ttggaggtaa aaaatatgta ctcaaatgaa gactataaat ttatagaaga
     5221 aaatgcacca tgttatatat atgatgagac taatataatt gaaaaatgta aggaattgaa
     5281 aaataatatt ttaggttttg attttttata ttctataaaa acaaatccat ataacaaaat
     5341 tgtaaaaagc attgcagagc aaggttttgg agcagatgct tcttcaacta atgaagttat
     5401 gatttcatca gaatgtggag tttctaaaga tgatatttat tattcatcac caggcaaaac
     5461 agagattgat atagaaactg ttttagataa atgcataatt attgcagata gtattacaga
     5521 aatagaactt ataaataaga tatctaaaaa gtataatcag aaagttaaaa taggaataag
     5581 aataaatcct gattttacta tggatgatga tagtgctaaa tcaagcaaat ttggtataga
     5641 tatagaagat atgagcagtg tttttaagat gttaagtatg tgtgattatg tatctgtagt
     5701 tgggattcat atacatatta aatctcaggt attggatttt gaaaagttag gacattatta
     5761 tgaaaaatgt ttttttatag ctttaaattt aaataaaagt aagtatatta atattgaatt
     5821 tataaatttt ggtagtggac ttggagtagc ttatgataat cttagagaaa atccacttaa
     5881 tcttaaagag ctttcaaaat taactcaaaa gattgctttt actaattcaa acacactaaa
     5941 atcaagactt cttattgaat caggacgttt catagtttgt aaatcaggta attattatgt
     6001 taaaattgta gatattaaag tatcaagagg gaaaaaatat cttattgtaa aaaatggact
     6061 taatggattt atgagaccta ttatttctaa tttaattgaa aatattactt gtggagtaga
     6121 attagaaggt caagagccat tatatacatc aaatcatgcc ttttctcttt cagtattaaa
     6181 taatttaaaa gaagaagagt atgtaaatgt tgttgggaat ctctgtacat cattagatgt
     6241 aattgcaaat aatgttaaat tgaaaaaagc aaacatagga gatttgattt caattagtaa
     6301 tgctggaagt tactcctatt ctttatcacc gctattattt tcaagttatg aatttcctaa
     6361 acaatattat aaaagaaaag atggatatat tgagtaaaca atagcataaa ttaataaact
     6421 tagtattatt gaaaaaattt aaaatgcagg gggtgtaatt ctatatggaa ttgtggaaaa
     6481 gaaatttatt tgtatgttgg ataggtatgt tttttagttc tatagggatg agccaaatag
     6541 cacctatact ttcattatat attaaacagt tgggggtaac tgatgttagt ttaatacaac
     6601 agtattcagg tatagttttt ggatgtacct ttgtagtagc agcattcttt tcgccaattt
     6661 gagggaaagc tgctgataaa tatggaagaa aatcaatgct tttacgtgca agtattggga
     6721 tgggaatagt tatatttacc atggcgtttg ttcaaaatgt ctatcagtta ttaggattaa
     6781 gaatacttca aggagttttt acgggttatg ctactgcatg tactactctt attgcaacac
     6841 agacagataa aaatcattca ggatgggctt tgggtactct tgcaactgca tcaactactg
     6901 gctcattaat tggtccaaca gtaggaggat atatagaatc aatcttaggt cttaaaagta
     6961 catttattat aacaggagga ttgttgtttg tatcatttat catctctatt ttatttgtag
     7021 tagataattt taaacctaaa gaaataaaag aatcaatttc tatacctaaa gaacaattaa
     7081 atatattgcc aaataaattt ttaattgcat ctatttttgt aaccacattc attactcaac
     7141 tagctttata ctctatagaa ccaattgtaa ccatatatat atcacaactt acaaattttg
     7201 catcaaatgt agctttaata gctggattga cattttctgc atcaggatta gcaaatttat
     7261 tagcagctca aaaacttgga aaaatgtcgg ataaaatagg tcctcaaaaa gtattgttaa
     7321 tttcactttt atgggctggg attatattta taccacaagc ttttgtaaaa actgcatggc
     7381 aactgatgtt gttgagattt ttattagggt tgtcagttgc agggcttaat ccttctgtta
     7441 acagcttgct taaaaaaatt gcaccagaag aatatgtggg aaaaatattt ggatataatg
     7501 catctgccca gtatataggc tgttcatcag gagcattttt agggggacaa atatcagcac
     7561 atttaggtat tagaacagta tttttttcaa caagtttatt gttgtttatg aatgcacttt
     7621 ggatgtataa atttactgga ttgtttatta aagataagac taaataatca tactatttac
     7681 atttctaatt ttatgatgta aaataaatat tttttatgta atttatcata gaattatata
     7741 aaaaataacc ctatggtaaa aattggaaaa tattattatc gacaaaatct ttgacttaaa
     7801 aactatattg cgatagtatt aatttaataa aagtttgaga ggggcgtaag gttatgacaa
     7861 tttcaaaaat accacaagca gaattaaaag ttatgaagtt tatttgggaa aaaaatgata
     7921 cagtaacatc aaaagaaact attgaagcta tggaacgaaa atatggttgg aaacaaacaa
     7981 ctacattgac acttttatca agacttgtta aaaaacattt tttaagtgca gaaaaaatag
     8041 atagatacac tcattataca atagttgttg gacataagga gtatttaagt gttgagacaa
     8101 aagatttttt aagcaatata cacgacaatt ctttacagag tttaatttca gcactacatg
     8161 atgatgaagt tgttgataaa gatatgttgg atttatttga aagtcatttt aaaaatttag
     8221 aagaagagta attatatcag gatagaactc taagaattta attaatctat ggctgaaaac
     8281 cataaatggt attatttaat cagctactca ctattcataa agtaatatta aataggttct
     8341 ctaattagta aaatgcctaa aataattgga atagggagta tcaagttaaa tgataccact
     8401 tatttaaata agaaatgatt tttaaaattt aaaataattt tataacttgt caatattcat
     8461 taatctaaag tattatttct atttaaccat atcaaaatat at
//
LOCUS       DAMJWC010000113         8156 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMJWC010000113 DAMJWC010000000
VERSION     DAMJWC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8156
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.118"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..597
                     /locus_tag="PC503_003442"
     CDS             <1..597
                     /locus_tag="PC503_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2529393.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            728..1750
                     /locus_tag="PC503_003443"
     CDS             728..1750
                     /locus_tag="PC503_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2529394.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1914..2471)
                     /locus_tag="PC503_003444"
     CDS             complement(1914..2471)
                     /locus_tag="PC503_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2529395.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2477..3553)
                     /locus_tag="PC503_003445"
     CDS             complement(2477..3553)
                     /locus_tag="PC503_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF2529396.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC503_003446"
     CDS             complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC503_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF2529397.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC503_003447"
     CDS             complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC503_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2529398.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5391..6320
                     /locus_tag="PC503_003448"
     CDS             5391..6320
                     /locus_tag="PC503_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529399.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6481..6930)
                     /locus_tag="PC503_003449"
     CDS             complement(6481..6930)
                     /locus_tag="PC503_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529400.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7133..8113)
                     /locus_tag="PC503_003450"
     CDS             complement(7133..8113)
                     /locus_tag="PC503_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2529401.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDRPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2818 a         1348 c          980 g         3010 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt gtctaattta
       61 gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag tcttggaact
      121 tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg aaaactatta
      181 aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt ggaaggtgta
      241 tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg aggtcaaaga
      301 caatcattat cactaattat gtcgtgctta acaaatccat cagttttatt acttgatgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac taataagatt
      421 gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca cgctcttcat
      481 tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt aaaaggtaaa
      541 gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtttaaaat
      601 aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa taattatggt
      661 tactttgtaa taattcatat gaatatatga acatatataa caataaattt ttgaggggga
      721 tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg ctcttagtat
      781 atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac aagaaagtaa
      841 ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac atccagcatt
      901 agatgccact aggacaggtt ttgtaaaagc attagaaaag aacggattta aagatggaga
      961 aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac aaagtattgc
     1021 gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc catcagctca
     1081 ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga gtgaccctgt
     1141 tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg gaacatcaga
     1201 ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta aggcaaaaac
     1261 tataggagtt atgtacaata ctagtgaagt aaattccaaa gttcaagttg atgctttaaa
     1321 agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta cttcaaatga
     1381 agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg tccctacaga
     1441 taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga ataaaatacc
     1501 tgttatagca gctgaatctg gtccagttga aaaaggtgct cttgcttgtc aaggtatcaa
     1561 ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa atggcgaatc
     1621 agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta atgaagatat
     1681 attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg taaagactaa
     1741 acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat aaattaattt
     1801 atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt atatgtaaat
     1861 gctcttaatt tgtttgtata aattttactt gtataaactt tatacaatca tatttattct
     1921 tctattttct ttattactct acatggattt ccaacagcta cagtatttgg tggtatatct
     1981 tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat tcctggtgtt
     2041 atgattactc ccccacctat ccatacatta tcacctattt ttataggaga accatactct
     2101 atgcctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat ttgaacgttt
     2161 ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa aatacaatca
     2221 taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca cctaatattt
     2281 tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat atcttctctt
     2341 ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt acaatactct
     2401 ctttctttta ctaacaattc atcatttgca tagtatcctt tcccagacaa cattttttct
     2461 ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa aataaatatt
     2521 cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta cttttttcca
     2581 attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca tatatagtat
     2641 atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca tttaaatctt
     2701 cattagaatc caagacctta atatgatgct ccctgattcc cacatattct atattatcac
     2761 ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata gtatttttat
     2821 ccagtctatt taatttggat atatttttac accctgttat cttagcttct ataaggtact
     2881 ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct ttgttgtaca
     2941 ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca aatagtatat
     3001 ctcccttgta atcttttaac atattcataa gttctttttc catattgctt cttaaatgat
     3061 ggtccaatgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt gccaatgctc
     3121 tagctagtgc taccctttgt tgttgaccac cagataattg ccaagggtat ctcccctcaa
     3181 acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt tcactcttac
     3241 ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga aacaaagcat
     3301 agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc ttcttttcag
     3361 aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc tcaagccctg
     3421 ctatacattt taatgtcata ctttttccag aaccagattc tcccaaaaac cccagagtac
     3481 ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt tcaatatcca
     3541 cgtataagct caactatcca cacctctttc ctataatttt ctgctgaaat tccgaccaat
     3601 aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc cacatcatag
     3661 ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata gtttgagttt
     3721 ttccaggtat atttccagct atcataagtg tagcaccaaa ttctccaaga gctctggcaa
     3781 acgacagcac caatccacca attattccag gccatgctaa tggaactgca atcttaaaaa
     3841 atactttcca ttcattaaga cctaatgttc tagcagctga caacatatta ttatcaatct
     3901 gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact actgctgaaa
     3961 ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa aactttccta
     4021 taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt ggtggcaaaa
     4081 ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta tagttagcca
     4141 taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa atagatgtct
     4201 taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta attttaaatg
     4261 gaaatagtga aactaataac tctattaatt tcactatttc cattttatta taatacacaa
     4321 ttattttcaa ttttcattta tttatatata atttatactt aattacacat aatttatttc
     4381 taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc tgactcactt
     4441 aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt aattactgaa
     4501 actggatatg taataggcga atgagttttt tcgtctgttt tttcaactac ttttatctta
     4561 tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc tgattgcacc
     4621 catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa cttatctttt
     4681 aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact ttcagcttca
     4741 ccaacagcaa ttttcttcac tttatctgta gtcaaatctt tcatacctga tacactactg
     4801 tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt atcagaaact
     4861 aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat aaataaatca
     4921 caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata gttaactgta
     4981 agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat tgcttctttt
     5041 aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt tgttttttct
     5101 tgttttccat catctttttt gtcttcatta ctattgcacc caactgtccc caaagttaaa
     5161 catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct ttttgtaaat
     5221 ttgatacaca ttttaacatg ttttattatg ttttatcatg ttttgttata tatagtttaa
     5281 ttatatatac atgataataa attttcaagt aatttattta cactactttt aaatattttg
     5341 ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt atggactcat
     5401 tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa aatactgtat
     5461 atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa ataagagttg
     5521 atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta aaggatacac
     5581 atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt tctggtcaag
     5641 atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga ataagtacat
     5701 ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc agagtttcta
     5761 tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact tttgttaaaa
     5821 agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg caaggtttct
     5881 atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca aaaccaagta
     5941 taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat ggtaaactta
     6001 gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa ttatcacatc
     6061 ttggagttgc aagtactgtt tctcgtggaa tagcagatgt tggtttggga aatgaaaaag
     6121 ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc tatgatttag
     6181 ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac ataataaact
     6241 ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact gatactggaa
     6301 aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt tataattttt
     6361 cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca aaaaatttat
     6421 gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa tcatattata
     6481 ttaatatata tttacataat agtatttttc tttaatgtag attaacatat gatatgtttt
     6541 aaacatcaat ccccttgctt tcttatatat atttggcaac acatatgagt ttaataaatt
     6601 atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta taaaattacc
     6661 tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat atcttcccac
     6721 taggtataca cactctacaa taaataataa aaatacaatg cagtcagtac ctgttgtctt
     6781 atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca aagtatcacc
     6841 cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa tattcaacat
     6901 gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct ttagatttga
     6961 ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg gtagttattt
     7021 tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa acataaaaat
     7081 agcctatcta ttttttaata aatacaaaaa taaataagct actaatattc aattaacttt
     7141 tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat actgtactat
     7201 catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct tttttatcat
     7261 gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta tcttttgttc
     7321 catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt tttacatcac
     7381 tgtaccaaaa tccagattta aacttattat ataaatctcc acaagtcacc acataattga
     7441 ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct ttcatttcag
     7501 aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt atctctgaat
     7561 gcatagcagc tgtccctgcc cccatggaaa atccatgcac tcctaatctt ccttcaggaa
     7621 atttattttt tacaaattta actagactat ctaaatcata cctttcataa agaccaaatg
     7681 tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat acgttataac
     7741 ctttatctaa atatctatat gctaccttta acatttcata gtaactactt ccaattccat
     7801 gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga ctttcaagct
     7861 tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt aatttctcca
     7921 gtggtctatc ttttctctca gaaaatattt ttactatatc ttcgtttttt attaactgct
     7981 ctaaaccaac tgaactatta tacactaatt tgccaaatat ataagataca attaatagga
     8041 ttaatagaaa cacaattgat ataattataa atttatttct taaactaata caatttttaa
     8101 aactattttt catatttatt taccatacaa ttttcctata ttatattttc taagta
//
LOCUS       DAMJWC010000114         7865 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMJWC010000114 DAMJWC010000000
VERSION     DAMJWC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.119"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     misc_binding    106..317
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            480..1769
                     /locus_tag="PC503_003451"
     CDS             480..1769
                     /locus_tag="PC503_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2529402.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1823..2902
                     /locus_tag="PC503_003452"
     CDS             1823..2902
                     /locus_tag="PC503_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF2529403.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2923..4467
                     /locus_tag="PC503_003453"
     CDS             2923..4467
                     /locus_tag="PC503_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF2529404.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4630..5172)
                     /locus_tag="PC503_003454"
     CDS             complement(4630..5172)
                     /locus_tag="PC503_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF2529405.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5320..5604)
                     /locus_tag="PC503_003455"
     CDS             complement(5320..5604)
                     /locus_tag="PC503_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2529406.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5667..6431)
                     /locus_tag="PC503_003456"
     CDS             complement(5667..6431)
                     /locus_tag="PC503_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2529407.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6713..6979)
                     /locus_tag="PC503_003457"
     CDS             complement(6713..6979)
                     /locus_tag="PC503_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2529408.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7021..7830)
                     /locus_tag="PC503_003458"
     CDS             complement(7021..7830)
                     /locus_tag="PC503_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529409.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2742 a          999 c         1283 g         2841 t
ORIGIN      
        1 aatttacata taaaactaaa aaatgcaagt aattgacttt ttaagttgac aaaatattgc
       61 atatatatta tgatataaat cataaattaa ctacaaatca atattatata ttcgtagaag
      121 aagaaagtag cataaaggaa ttttacagag agttagattt ggctgagaac taatattgga
      181 atttatgtga aaaggacttt ggagaatact attgtaatta tgttagaata gtggtttaat
      241 tcgccttaag aaaatgagtg agtaaaatta atttttacta ataagagtgg taacacggat
      301 ttatattcgt ctcttggatt tttccaagag gcgtttttta ttataaactt atttcagaaa
      361 atttaaaact atatattaaa tgaaaattat aaaaatatga tagttaataa atttataaat
      421 tagaaaattg taaaatatgc taaggtcagt agttttacga tttaaatgga gggatgaaaa
      481 tggaagaaga aaaaattaac tatgctctgg aacagattcc agagaatcaa aaacgtggtt
      541 gggtagctat gttttcagtt ttagtagcaa taggtgtgga tttatcatct gttattttag
      601 gcgctgagtt ggcacagagt atgccaatga aacaagcaat attgtcagta attgttggtt
      661 catttttttc tgcaattttg tatactacat gctctttggt tggttcatct acaagtttat
      721 ctacatctat gataacaaag tatgtatttg gagaagctgg agcaaaaata ttttctctag
      781 ttataggggt ttctctatta ggttggtttg gagttcaagt aggtttcttt gctcaaaatg
      841 cacagataat aataaaagat atatttaatt tagatgtcag tatgcagatt ttaagcctaa
      901 taggtggtct cttgatgatg agtactgcaa tttatggata taaggcaatg gagaagttga
      961 gtgtgtattc agtaccattt ttattagttc ttatgatgct aactatattc ttagctttta
     1021 gagcaaatgg aatttcagtt gatgataata tgaaatctac tatgacattt gcaggtggag
     1081 tttctctgtc aatgagtata ataatagttg gtgcaattgt atctcctgat ataagtcgtt
     1141 gggctaaaag tagaagagac tgtgctcttt caagcttttt gggaatacaa tttggaaatg
     1201 cttttatgat aatagtttcg atagtattag taaaatgtat gggaacttca gatattatga
     1261 gaatttttat tacattagga attgctatac caggtataat agtacttaca ttagcacaat
     1321 ggactacaaa tacaagtaat gtatattcag catcattaag tatagctctt gtacttaaga
     1381 aggctcctga gaaagtatta actatagtcc ttggtattat agcaacatta ttggctgtat
     1441 ttggaatata tgaaggtttt ataggatttt taaatttact tggaattgta attgcacctg
     1501 ttggtggtgt atatacagca gaatattaca tagtaaagca agaacttaaa ggctttgata
     1561 aaggagtatt atataaacca atagttaaac gttcaatagt gtcttggata attggtatat
     1621 taataactta cctttcaaca tatggattta taactcttac tactatagca cctttagatg
     1681 gttttatagc agggtttgta gtacaatcta ttattggaaa agtgctttgt tcaacaaaaa
     1741 ataagcaaga aatagacaaa gcagtataaa gaaatttgtt tataaagtat aaaataaatt
     1801 agaaatatga ggagaaagta acatgagatt tttaacagaa gaaagtgtag ataaaatagc
     1861 agttggtgca gcagtgcttg gaactggagg tggaggtgac ccatatgtag gtaaattggt
     1921 tgcaaaacaa gccattaaaa agtatggtcc tgtaaaagta ataagtttag atgaacttga
     1981 tgatgatgct ttggtagttc cagtatctgg tatgggttct cctgtaatta caatagaaaa
     2041 attactttca gaagtagagt taactacccc tttagaaata atggagaaat tattaaatag
     2101 aaaagtggat gttataattc ctatagaaat aggagggata aactcactta tgcctatagc
     2161 agttgctgct aaaaaaggac ttcctatctt agatgcagat tctatgggta gagctttccc
     2221 tgaagctcaa atggtaactt tttatcttga aggatatgag gcatctcctg ccgtaatgtc
     2281 tgatgaaaaa ggtaattctg ccatccttta tcctgtggat ggaatttggt cagaaagatt
     2341 agctagaact ttaactgtag aaatgggagg aagttcttct attagtgact ataatttaag
     2401 tggagctcaa gttaaaaaag ctgctatagg taatactctt acaatagctg aaactatagg
     2461 agggttttta cttgaaaata aatctgattc aaaaggtgct gttgagaata tactaaaaga
     2521 attgtgtgga tacaagttat ttgaaggaaa agtaattgat attaagagag agttgaaagg
     2581 tggatttact agaggacatg ccttttttgc tgggattaat gagtatgatg gagagtattc
     2641 tatattattc caaaatgaga atttaattgc caaaaaaggt gatacaccac tttgtattac
     2701 accagattta atagcagtat tagatttaga aactggattt ccaataacta cagagagaat
     2761 aaaatatggc tctcgtgtta tggtagtagc ttttccttgt aatgaaaaat ggagaacaga
     2821 aaaaggaatt gagacagttg gacctggata ctttggatat gatgtggaat ataaaacagt
     2881 agaagaatta caaggaaaat aaaagtttag gaggaaattt tgatgtatcg tgtaggaatt
     2941 gacgttggag gaacaaatac agatgcttgt atactggatg gggaattaaa agtaattcat
     3001 tcagttaagg tggcaactac aaaagatgtt gaaactggtg tttacaatgc cttaaaaaaa
     3061 gttatagatg aaagtaagat tgaccattca ttaataaaat atgctatgct tggtacaact
     3121 cattgtacaa atgctattgt agaaagaaaa agacttaata atgtggctat gataagaata
     3181 ggaaagccgg ccactactgc cattcttcca tttatagatt ggccagaaga cttaagagaa
     3241 aaaatagaat tagattcaat attggtatct ggtggatatg agtttgatgg cagaaaaata
     3301 aatgaacttt gtaaagatga agttgtagag ttttgcaata gaataaaagg caaagtggaa
     3361 agtgttgcaa taagtggagt atttgctcca gtaaataaac aacaagaaga agaagttgca
     3421 aaatgggtta gagaaatttt aggggatatt cctatatctt tatcaaatga aataggtaat
     3481 ataggtatat tagaaagaga aaatggagct attttaaatt ctgcattgtc tcaagtaggt
     3541 aaagctgtat ctttaggatt tgaaaaagca cttaaagatt taggtataga tgctcaaata
     3601 tatttcagtc aaaatgatgg aacattaatg aatttagagt atacaatgaa atacccaatt
     3661 tttacaattg gatgtggaat aacaaattct ataagaggag cttccttctt atcaaaagta
     3721 aaaaatgcaa tagtattaga tgttggtgga actacaagcg acttgggtgt actatataat
     3781 ggattcccta gagaatcatc tattccagtt acaattggag gagtacatac aaactttaga
     3841 atgccagatg ttttaactat tggtcttgct ggtggtacat gtgtaaaagg cgaaaaagat
     3901 aatataaaga taggtcctga aagtgtggga tatagaataa ctgaagatgc aataatattt
     3961 ggtggagaca ctctaacttt atcagatgtt gttacaaaat tagatatggc gtttgaagat
     4021 agaaaaagca atgttgaaaa cttagataaa gagtattgta atgaggtata taagaaggtt
     4081 attttaaaat tagaagatgc tgtagaccaa atgaagacta gtcaagatga tgttgaattg
     4141 gttttaactg gtggaggaag tataattgtt cctgaaaaac taaaaggcat aagcaatgtt
     4201 ataagacctc ctcattatac tgctgcaaat gctattggtg cagctttagg acaaataagt
     4261 ggagatgtag aaaaagtata cagtttagat aaaatgtcga gagaagatgc catagaagat
     4321 gcaaaaaaag aggctgtaaa taaagctcta aaagctggtg ctaaagaaga tactatagaa
     4381 gtattaaata tagaagatgt tccacttgca taccttcctg gtaatgcact tcttataaaa
     4441 gtaaaagttg ttggtgattt aatttaaaga ataaatataa gtatttccag aattatataa
     4501 atatttctgg actcattttt aaacttattt tatcaataaa aacagcataa cttttgacta
     4561 tattcttata agtttccgaa cagccgatat atacctattt tttgaggttt atcggctgtt
     4621 tgttatcttt tatcgcattc caactatttt tcttaccgta tttgctgtac gaattgtaat
     4681 cttatcactt acatttgaac tggcagtctt tgaccaccaa tttgtctttt tataatcttt
     4741 acgactaaaa gaccaaaaga tagcattttt ataatgatat actttttcat actcttcttt
     4801 aggatttcca acctcatcat aaaactcgtc ataagataag tcaggaaaca taaaaataag
     4861 attatcatat atttctttgt tgttatctcc ccaccaatta ggagcattat ttagtatatc
     4921 ttttaactct tcttgtgaaa taataaaaac tggtatttcc aattcaaact gtttttttat
     4981 cattaatctt attgtatttg agataacctt gctgtcatct acatcactta aaaagacaac
     5041 attaccacta ttaaggtatg tagaaacttc tgaataacca agttctacaa agcttgcttt
     5101 taattcagac ataattatct tgttcttacc acttatattg atacctctta ataatgcgat
     5161 ataacttttc atataataat ttcacctcta aacattcaca tttttctatg tagtacaaac
     5221 ttgaatttgc atcttttata attctttcaa aacttcttca tatgtaattt ttttaatata
     5281 aaaaaatcgg tgcttaattt gtaccgattt ttgtttttcc tagtaaagaa ctcgtttttt
     5341 tgcttctgct atagctctag cagcactttt tgcttgcatt cttttttctt cttctttttt
     5401 aaattcattt attgtttcat ttagattctt atcatgttca tttttttctt tatcttcgtt
     5461 ttctctgtat actaatatat aatctattat tgattcgttt attatctgag atatactttt
     5521 attttcatta attcctattc tcttaacttc cttaagtaga gtctcatcaa tatgaaccgt
     5581 tgtttgcttt gtattttttg ccaccttaat cacctcttaa aaaaaattct aacattaaaa
     5641 ttttttttag tcaataaatt ttaatattaa aattctttaa atgttttatt tgattttcta
     5701 aaattttcta ttgtatttat catcttattt tttatatttt cacctagtac agaagacttt
     5761 agtctaggat tttcgatatg gtcataaatt ggttctaaaa attcaacttc gacaggaaca
     5821 gagttaattt taccaatagg ttggtatcct tcataagtat cttttgaatt ttttattacg
     5881 agtggaacaa tagggcattt tgctttatat gctatcttta aagctccact tctaaactcc
     5941 gaaaccaatg aatttggttc tttaatccat gttaaatctc cttctggaaa cactgccata
     6001 ctttgacctg taagtatatt ttgagaggct tgggctatac tctttatacc ctcacgattg
     6061 ttttttctgt ttacatatac acatcttagt aattttgccc attctttaaa tataggtata
     6121 tttctccaaa ctggttcatc tgcaattaca catccaattg gtctttctac acttgctgtt
     6181 agtatgaagc tgtcaagcat actagaatga tttacaacaa atagaagtgg ttcttttggc
     6241 agtgtttcct taccaattat attaagctct atattcacta tatctaaaga ttttttagct
     6301 tgtttttgca taaattcaaa tttttccttt aagctaaatt tatcaggatt ctttttaatt
     6361 ttaataagcc taggtataga agatgtaaaa cctataagtt gatatgtagc aaattttaag
     6421 taattattca taaaattatc tccttaaaat aaaattattt attactgtaa agattttaac
     6481 ataaaataaa atttaagtct attttaattc aattttgtaa catatatttt aaatagacag
     6541 agattgagat tttatatttc caattttagt aatcagattt tatcaataaa ttactattct
     6601 attaatttaa ttaaataacc tttaaattta attataaaaa ctgttgcaga aatttctaca
     6661 acagtttaaa aaatttacct tacaaaaact tattttataa caagagagta tattataagg
     6721 ctagtacagc ccattttttg cactgagaaa ttcttttgcc atcatcacct tgttctttgt
     6781 catatgcaaa ttgattaagc atttcacatg gaaatgtatc acatagacca caatgtgtaa
     6841 ggtttttatc ttcacaacaa gattttacag gacattgttc accccaaaat ggtttctcaa
     6901 tctctgtaca acctttacaa ttgacttttt ccttgtatcc acattcataa cataaaattc
     6961 cacatcttga ttctatcatt ttaagtcact ccttaaatat aaattttata tgattgtata
     7021 tcaaaattta tacttttcat tgtaaaaatc ggacaaattt tttatatagg ttgttggatt
     7081 aacaccacaa atagatttaa aatcatttat aaaatgagat tggtcgtaat aaccaatatc
     7141 ttgtgctaaa gttgcaaatg gtattttatt attttgtatt tcttgtaata caaggtttat
     7201 acgaagtaat ctaaggtatg atttaacact cataccaaga gaattattaa aaattctatt
     7261 taaatgtcgt tcactataac aactaatttg tgaaatgttt ttaacagaca taatagagtt
     7321 ttgttttcta gcattttcaa gaattggtat agtcatatct actatatttg atttcaataa
     7381 gtatgataag aataacatat ctaattgttc tactaattcc tttatagtac ttgttctttc
     7441 aaaaatggaa ttaacctcta agctaaataa tgtgttaaaa tcttcaagtg aaatttttaa
     7501 atctgtagat tctctttgag aaagacctgt caaataatat actccacctg ggcgaaactc
     7561 aacgaatact ctaaaaagta cattttctat atcatttttt acaatagtag tttttgttgt
     7621 ggctccccag aatgcgcttt ctataccttt tttgtcaaat ttaaatatca tacatccact
     7681 agcatcaggt attaatgtaa gattttcttt aatacttgta tctggaatag atattgtata
     7741 gtgtgctata tactgtctta acaatttatg tggcaaaata tatgtatact gtttgcaggt
     7801 atttaaaatg ttattgatta ttttattcat aagtatatcc tcctgatata taaaaaataa
     7861 gtata
//
LOCUS       DAMJWC010000115         7731 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMJWC010000115 DAMJWC010000000
VERSION     DAMJWC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7731
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.120"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(318..980)
                     /locus_tag="PC503_003459"
                     /pseudo
     CDS             complement(318..980)
                     /locus_tag="PC503_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(1140..1676)
                     /locus_tag="PC503_003460"
     CDS             complement(1140..1676)
                     /locus_tag="PC503_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2529410.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1749..2162)
                     /locus_tag="PC503_003461"
     CDS             complement(1749..2162)
                     /locus_tag="PC503_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2529411.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2628..3182
                     /locus_tag="PC503_003462"
     CDS             2628..3182
                     /locus_tag="PC503_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF2529412.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEDTI
                     SGMQGTISDMQGSISSMNGTISDMQGSISSMDGTINSMQDSITDMQVEIKEVNSRLDN
                     MEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIK
                     NDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3790..3969)
                     /locus_tag="PC503_003463"
     CDS             complement(3790..3969)
                     /locus_tag="PC503_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2529413.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4195..4728)
                     /locus_tag="PC503_003464"
     CDS             complement(4195..4728)
                     /locus_tag="PC503_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2529414.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(6476..7048)
                     /locus_tag="PC503_003465"
     CDS             complement(6476..7048)
                     /locus_tag="PC503_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2529415.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(7110..7373)
                     /locus_tag="PC503_003466"
     CDS             complement(7110..7373)
                     /locus_tag="PC503_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2529416.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(7373..7594)
                     /locus_tag="PC503_003467"
     CDS             complement(7373..7594)
                     /locus_tag="PC503_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2529417.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2673 a         1327 c          927 g         2804 t
ORIGIN      
        1 atagcttgta gtgtacttcc ctcaagagga atagtcgttg aagtttctcc tattcggagt
       61 ttacctgctg attgcccatt ttaaagtact tagggtttaa ccttatacca tctaaccaat
      121 tttttctact ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt
      181 tagctttagg ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca
      241 tataggtttc cctatatgct gactatttta gctactaact catgactaaa gtcacaagtg
      301 ttcgtagcta ttttttaatc aaactggaat acagactcca ttcctaggaa attggctgaa
      361 atatagtctg ctgtcaaaga tgctgtcatc acagaaatta aaacagatac tgaaaagttt
      421 ttatggactt cttcaagtga aaacataaca cccgctagtg gtgcatgaaa ggctgctgat
      481 aatccagcac ttgccccaca ggttaacagg aatttttcct ctgtcttccc tcggtcaaga
      541 gctctagaaa tacctttacc tgccatagca ccaagctgaa tggaaggacc ttcccttccc
      601 aaagcaagac cacccatgag tgataagaat cctccaataa attttgttgg caacactcgc
      661 caccatactt gttttatttt ccctgtcatt tccccctcaa gctgagggat accacttcca
      721 gaaatcattg gctcccagtc caccaacttt gatacaatcc acgcaagtac tgcaagtact
      781 gcaaaccaag ctattatttt tattgtagaa ccttctacaa attttaaaat ttggctaagc
      841 caagtaccag cctgccctaa aagtatcctg tataaaagca caatcaaacc agccacagcc
      901 ccaaccataa gtccttcacc aatcaaaatt acctgaaagt gctctgcccg tttgataata
      961 tgagatgtat cctttttcat actattcctc cttcatccaa taattctaca caatctgaat
     1021 ctccaatgac taaagtcatg agtgtgtaca gatatttttt aatcaacaaa aatagatttt
     1081 tacttactaa atataagaaa ataattgctc aatttctcaa taaatgtgaa tttattcttt
     1141 taggtattta ttctccacag tcgtgcttct tccagcaaaa tatttattaa ttcttgcttt
     1201 ctctgtgtat agattttacg attgtcctca aactgtaatg ctaatttttg tttatgacta
     1261 tcatagagtt ttgctttgtc tgtaaaagta tttagataat ctcgaaaatt gatataatta
     1321 ttccatgcaa cactattcca ttcaacaaca tgaatatggt gagtacgagt atttttctca
     1381 aaatctccca tagcaaaaag taattgtttt ggtacatcct gacctcgaaa aacgattcca
     1441 cattgctcta acctttcgag gtataattta gcttcctcta aagaagcaac acctacaaca
     1501 atatcaataa taggctttgc gctaatactg ggaatagaag tgcttccaat gtgttgaata
     1561 tcaatagcag tcttatccca tatacttttt aataatataa tgacatcttt tgcactttta
     1621 tcccatatca tctgatgttc caataattta accataccac attttaaacc tatcactata
     1681 taccacctca atataatcca cctttatata tattacaatt ttttctatct tgataaatag
     1741 tgatttagct atttcacttt ttcttgacac tcgctacatt ccctatcatg aatagatata
     1801 attcctccac atttagaaca agtatatctc tccttctgct tttgcataaa cttctctaaa
     1861 ccgtactgct gaacaaattt actattttcc ataaggcttg cttgatatct cttgttataa
     1921 cttttttcaa gattttttat gagtttacaa ggaaaattga aacattcaaa acaataaaac
     1981 aacccttttt gacagacaca atcctttatt ttgcacttac ggcagtgttc tggctttcct
     2041 gtatcgccgt tcaaacaacc agcacatggc tttttgtgat aacaatgctt atagcaaacc
     2101 atacaattca ttccacaagg agcaaacata atcgtatcaa tactctcttt tggcattttc
     2161 ataacatttt actcctttca aaaatccaat ttgtcgaatt gttatatatt catattgtaa
     2221 cataaaaaat agctaaaaaa ttcatgcact ttcattgcca ataaattttc aaggaaatat
     2281 gaaagtttaa aactaagaat aaaaagagat aaaaaggaag ctactaatca aaatattcaa
     2341 acacaagtaa tcaatataaa taacttaagg tatatttaaa agtatatgat attaccagca
     2401 gttttaaata caaatataac cacacatgcc tcaaaaacac ttattacagt atcttagaaa
     2461 cttagacaat acataagatt cattaataaa aaagttctca atatagatat atttaaccct
     2521 gttttgaata gtagataatc atatgattaa aaattaaata tgacatagcg tttgtggaat
     2581 ataacaccta aattatgtta taataataaa gcaggagtgt gatagtgatg gatgaaaaaa
     2641 tattagagtt attacaggaa atgcaaggta atattagtaa tatgcaaggt agtatcagtg
     2701 gtatcgaagg cactattagt gatatgcaaa gcaatattaa tggtatcgaa gacactatta
     2761 gtggcatgca aggcactatt agcgatatgc aaggcagtat cagtagtatg aatggcacta
     2821 ttagcgatat gcaaggcagt atcagtagta tggatggcac tattaatagt atgcaagaca
     2881 gtattactga tatgcaagtt gaaattaaag aagtcaatag taggttagac aatatggaac
     2941 ctgatattaa agacttaaaa actggacaag ttgaaactag tagtagactt gatactattc
     3001 agagtgatgt tacagaaatt aagtcagatg taaaaattaa cagaaataca ttagatacag
     3061 tgattaaaca tacctcttca ttagtaaaag atacatcaga tattaaaaat gatttaaata
     3121 atatagagat agtcacatct aagaattcga atgatattgc taaattaaaa tcagttaaat
     3181 aatatactat agtaaaaaat acctgaaaat ttcacatact tctttaaagt tataccaaat
     3241 tttatacaga aatactgatt atccgacaac acactttact tataaataat ttattaaaaa
     3301 aatactcatt ttatcctaaa attaacacga ctaaatgagt cttgatataa taataaaaaa
     3361 taagggagat tgaacactaa aaagttgtgt atctccctta tattctataa tatagttata
     3421 taatttttca gcctaaaata aaagtccatc tttgattaaa acacatcccc ttatcactta
     3481 taaaaggata aaatcttgtt ttcatttttc catttatatc ttcttgctta agagtaataa
     3541 ttttttcttt tgatacttta agtgattggt taaatttaac caaacgacta agttttgttc
     3601 aacatctatt tttcatattt tccaatactt aatctatttt ttataaataa ttcttttatt
     3661 tctaactcac ttacattttt tacataaaac gaagcatata aatttcaacc ttatcttgta
     3721 tggttcttaa tacttaatga gtagcttaag tatcaatcat tataaatttt tcccttacat
     3781 ttaacactct taccatttcc aaaatataca aaatatattt tgaacatttg tacaatgatg
     3841 aaatacaata catgaaaata caatatcata actgttgtct aaaaatagaa gttcttcaac
     3901 ataacctttc acaaaaaaca tattatctaa gtattttttg tctgctcctt gttttcctgt
     3961 ttgtagcata taaattactg catctaaaca tataactact cacacgaaaa aagaaaataa
     4021 acttccaaaa tacaagctct aaaaactacc tctaaagttg tataatgttt actaggaata
     4081 aggttgtata acatatagtt taaataatca ttttttaaaa ttgcaagtta ttgctttcaa
     4141 aattagatgt ttttatatca aataaatgat taagaatttc taaatttaat ggctttataa
     4201 tgcactccct ttctttggga taaaataatg ttgcacagat actttttcta aagataacaa
     4261 ttttattttt ctatcaattc caccagcata cccagtcaaa ctcccatttg ttcctacaac
     4321 acgatgacat ggaataataa tagagattcc attatgccct actgcaccac cgattgcttg
     4381 tgctgacatt ttagatattc ctttttgttg agcaacttta tatgcaattt ctccataagt
     4441 gattgtttta ccatatggta tttgttgtaa aattttccac actgtagtct gaaaaggagt
     4501 acctaccata tggagtgatg gtgtaaaatt gggttctttt cccgaaaaat aaatatctaa
     4561 ccatttcttt gtctgctcga aaattggcaa ttctttttct tgatgttctt ggtcaagatt
     4621 ataagcataa tacttttgat tctcaaacca aagaccagtt aacccaatat tatctgatgc
     4681 taaaagaata tttccaattg gactatggta atagctaata tattgcatac aattcctcct
     4741 tatattctga aaacttcact caaatcatta gacacttctt ttctatctac cattatgtaa
     4801 aaacatacta atataatttc cttctaacta cactttcgtt ataatatcta tcctcatatc
     4861 atattagttt tatatttacc tgcatctgtt catccttttt tccctttccc tttgatgaat
     4921 ataaaattca tacatttaag cttcctactg tattaacttt tatagaagtg tatattataa
     4981 ttttatcact aaataggcca aaaaaatatc gatatagcat caagtaatat cataatactt
     5041 tcaaatggga aaagtaagaa taggctgtaa aaaagaaaag tatttttatg ttagaaatcc
     5101 agtaaaatca ttagtagata gaataacaga aaacgaacaa tttgctattt atcattttac
     5161 acataaatat aattgacgca ataaagtgtt ttctattcta caacgattaa taaggttaga
     5221 aaaaagtaaa aatgaactgt atatgtatga agcattagtt tctgtttctt tcctttggct
     5281 tattatgata aaaaatattg ttttgctacc aataaaacac aaaaatataa ttaatatcca
     5341 tatgcaaaaa attttacgtt atattgaaaa atactattgt tttacattat attgaagggt
     5401 actattgtga aaacttaatt ttggagtact atcaagcagt ggtaatatca ataaatcaga
     5461 gtgctccaga tgatttgaac taagtttaaa tactatacct tataaatatt ttactgagtt
     5521 ttgtttatta aaagcaactc aatttctaaa aggcacaaat gagctaataa gtgacattgc
     5581 tataaaagtt gtttttcatc aaataatcta ttttagtaaa tgttttaaag aaaaaacggg
     5641 atattctcca aaagtgtaca gaaatataaa aaaagagata tgatttttta tttcttttga
     5701 ttatccaaag agtaaataaa aaatattgta aaaaacttac taacaacggc aatgctttga
     5761 actatggtaa tactttgaac ttttgattgg actttttttg ctaaaataat atatttaaat
     5821 agcaaagtaa tctgtttaat caataaaaaa taagagataa aagaaatcaa ctaaaacttt
     5881 tacctcttat tttgatagtt tatcagagct aatatttaca ctctttttat ttttgatact
     5941 tcattaaaaa tgatgcttac tctccattca cttttaattc ttcattaaaa atgatgctta
     6001 ttctccattc acttttaatt cttcattaaa aatgatgctt actctccatt cgcttttaat
     6061 tcttcattaa aaatgatgct tattctccat tcacttttaa ttcttcatta aaaatgatgc
     6121 ttactctcca ttcgctttta attcttcatt agaactatgc ttactctcca ttcactttta
     6181 attcttcatt aaaaatgatg cttactctct gttcactttt aattcttcat taaaaatgat
     6241 gcttattctc cattcacttt taattcttca ttaaaaatga tgcttattct ccattcactt
     6301 ttgattcttc attaaaaatg atgcttattc tccattcact tttaattctt cattaaaaat
     6361 gatgcttatt ctccattcac ttttgattct tcattaaaaa tgatgcttat tctctgttca
     6421 cttttaattc tttattaaaa ctgatgctta ttctccattc actttcaatt cttcattaaa
     6481 actgatgctt gcactctgta aactcataaa catccattaa tgcttcacca aatctttgat
     6541 agtgaactac ttccctctca cccaaaaatc tcaatatatc tttcaaatca gggtcatcag
     6601 ttaaatttat taattgatag tacgtagcca atgctttttg ttcagcagcc atatcctcat
     6661 gtaaatcagt taccgaatcg ccaaagacat taatataact tgtagtaaag tttactccat
     6721 tagaatctac tggctgaaga ccatgtccaa aattagcata attactacca agtccagcag
     6781 ccttaagctc ttctggagta caattgccta ttaattgata taacactgaa gaaattatct
     6841 caacatgagc catttcctct gtacctatat cagttaaaag tgcacgagat tttccagttg
     6901 gcatagtata tctttgttga agatatctag ttgcagctgc caactcacca ttaggtcctc
     6961 ccaactgagt catgatatat tttgccattc tagggtctgc ttgtcttatg ttaactggat
     7021 gttccagtgt tttttgataa atccacatat tatcttactc ctccttaata tatatttaat
     7081 aataaatcta attttaaagt ttaataattt tatttataaa atgatttgtc ccatggccaa
     7141 ggttcagata tccatgacca aggatattca cttgattcat atccaaaatt agttaatgct
     7201 ccatatttag attcataatc acacacagct tgtgtaaatt tatcgcagta tctgttgtat
     7261 gaatcaagag ctttcttatc ccttggattg ttatctaaat ataaatttaa ttctatacag
     7321 gcaaattgat attctgaaat tctctctaaa agttctcttc tatttaatga cattagtaca
     7381 tgttaccccc ttttttagct ctaactctat ttttaggatt tgcatatagc caatcattat
     7441 agttatttga ctctattaaa tctaattcag gaaataaagt acctcttttt aatgctgttt
     7501 ttggattgta tgtgtcatca taaatttgac gattgatgta tggtctagca aattcacaac
     7561 aatagtcttg tttatcctct tttaaatatc ccattaatta tcctccttaa tttttagaat
     7621 tttaaaatag cattattttt aaaaattgta tactggttct atattataac tggtagtttt
     7681 aataggtctt taataagatt aaatgattaa ataagtatct ttttttctta t
//
LOCUS       DAMJWC010000116         7674 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMJWC010000116 DAMJWC010000000
VERSION     DAMJWC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7674
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.121"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            44..1102
                     /locus_tag="PC503_003468"
     CDS             44..1102
                     /locus_tag="PC503_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF2529418.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRSIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1206..2390
                     /locus_tag="PC503_003469"
     CDS             1206..2390
                     /locus_tag="PC503_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2529419.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMIVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2597..3310
                     /gene="rpsB"
                     /locus_tag="PC503_003470"
     CDS             2597..3310
                     /gene="rpsB"
                     /locus_tag="PC503_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF2529420.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3389..4300
                     /locus_tag="PC503_003471"
     CDS             3389..4300
                     /locus_tag="PC503_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF2529421.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4385..5089
                     /locus_tag="PC503_003472"
     CDS             4385..5089
                     /locus_tag="PC503_003472"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF2529422.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5115..5672
                     /gene="frr"
                     /locus_tag="PC503_003473"
     CDS             5115..5672
                     /gene="frr"
                     /locus_tag="PC503_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF2529423.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDALLSKKEKDIMEV"
     gene            5675..5878
                     /locus_tag="PC503_003474"
     CDS             5675..5878
                     /locus_tag="PC503_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529424.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5907..6641
                     /locus_tag="PC503_003475"
     CDS             5907..6641
                     /locus_tag="PC503_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF2529425.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6654..7433
                     /locus_tag="PC503_003476"
     CDS             6654..7433
                     /locus_tag="PC503_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF2529426.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3162 a          781 c         1457 g         2274 t
ORIGIN      
        1 tacaaaatag taataattgt tttgtactgg aggatatata tttatgaatt gtaaatggat
       61 atctaaaata gatgagagaa aaaaatgtca tagagaagca gattcttctg gatattgtat
      121 ctttcataaa gaaaataagt ctgatgaaga aatacagttg atgatggata ctattcataa
      181 agaagagata agtgaattta atggatttgt ttttgaaaat gaatttaatg cggaagaaat
      241 attaacttac aattataaaa tactggattt ttctgaatcc atatttaaac aaaaagcaaa
      301 ttttaaaaaa tatattttta aaaagaatat tatttttaac tatacagaat ttagagataa
      361 agttttattt aatggttgtg tattcttaga aaactgtgat tttaatagaa gcatatttag
      421 taaaaactat ataaatgacc gtatatttga aaaagtgaaa tttaaaggac ctgatttggt
      481 agttaataaa gtagaaaatt ttccaagaat ggatggaata atttttagca tgtgtacaaa
      541 atttgtgtta aagaatgttg aatatggaaa aagtgagtat gagcatggca agataaatta
      601 tagaatagct agaaatcaag caacaaaaat tggagaatat gagatgatag gattttacta
      661 ttataaggaa agaatttata gtagtaaaat aatgaaacgt tctaattatc ctactttcag
      721 tgattattta gttgaaaaat tttttgacca aatagcacgt tacacaacag gttatggaga
      781 aaagccatgg aatatattat tagttattat agcaataata agtgtttttg ctttattata
      841 cttatttgta ggcatagaaa gttcaaatag cacacttgta gctttagata taaataatat
      901 aggtgattac tcactaagtg agattttcaa aatgtatatg gatttatggt attttagcat
      961 ggctacattt agtacagtag gatatggaga tatggttgct acaagtttga ttgggaaagc
     1021 attggcaggt atagaagtat tttttggagt tacaatagga gcaatttggg catctgtgat
     1081 tattaaaaga atgataaggt aatatttgtg taaatatgga taggtattaa ttactagata
     1141 taaattggac taaataggga aaatttaaat ataaatatac ttaataatcc aagaaggtga
     1201 aaaatttgaa aaatgcacta aaaaaaatta tatcattagc catgattcta gtttttataa
     1261 taccaaatta ttcatatgca gatgataaat ctgtagacaa gtattcaaaa acatctatac
     1321 ttatagacca agaaacaggt agagttttat atagtaaaga acctgatatg aaggtaccat
     1381 tagctagttt aagtaagatg atgacttttt tacttgcaat agaagctatt gaaaataaag
     1441 aagtaaaaga aactgataaa gtaaaaatag acaaatctat tgcatcagta aaagggtcaa
     1501 gttataaact taaagatggt gaagaagtgc cacttataga gcttatgaga ggtcttatga
     1561 ttgtatcagg aaatgatgcg gcaattgcta tagcaaaaca tatttgtaaa acgaaagaag
     1621 catttgtaga tagaatgaat aaaaaagcaa aagaaatagg aatgagtaat acacattttc
     1681 taaatccaaa tggtcttcca atatacgatt taagcaaccc caaaaaacca gcaaaagaaa
     1741 atatctctac tgcaaaagat atagctattc ttggaaaata catgtttgac cattatgaaa
     1801 aacaagtaac agctataact gatatggaga catatacaaa ttcagataga agttttgaaa
     1861 aaagcaatac aaatgcatta ttaagaatta taccagaagt agatggtata aaaactggat
     1921 atactggcaa tgctggatat tgcttatcat tttctatgat tgtaaataaa aatgataaaa
     1981 atgagaaaaa acgtagagta ataggggttg tattaggtac taaccataaa aataaaagaa
     2041 cctctgcttc attagctcta ctgaaatatg gaaaagaaaa tttcaatatg aaaaaagtaa
     2101 ttgataaaga tagctttatt ggtaagaaat atataaaagg aatgaaagag ttagaggtta
     2161 cattaaaagc aaaagatgaa ctttatacaa tattaaaaga tgatgaaagt ataaaatcag
     2221 aagttaagat taaaaatata gagtaccctg ttaaaaaagg tgatactatg ggtattataa
     2281 aatattatac taattcaggt gacttacttg gaagtgtaga tatagtaagt aataatagta
     2341 tagataacgt atcattaaaa acaaaattaa aaatgaaatt tgcaaattaa attcaaaaaa
     2401 tggtataaaa tacacaaaaa aatataaaaa tagaaaatat ggaaaaaata ttgttatttc
     2461 ttcacctctg tgatatacta ctagaggtga aaaaataaaa taaatcacac acagcattgg
     2521 gatccttaaa aggtgcctat tacatggttt tttagggaga agatcaagct ggaggtataa
     2581 aaccaggagg taagatatgt cagtaatatc aatgaaacaa ttattagaag caggtgttca
     2641 ctttggtcac caaacaagaa gatggaaccc taaaatggct aagtatatat tcacagagag
     2701 aaatggaata tatataatcg acttacaaaa aacagttaaa aaagttgaag aagcttacaa
     2761 gttcactaaa gaagtagctg aaacaggaaa gccaatctta ttcgtaggaa ctaaaaaaca
     2821 agctcaagat gcgataaaag atgaagctga aagatgtgga atgtactttg ttaatgaaag
     2881 atggttaggt ggaatgttaa caaaccacaa aactataaaa acaagaataa ataaattaag
     2941 agaattagaa aaaatggaag aagaaggcgt atttaatgtt cttcctaaaa aagaagttat
     3001 aaaattaaga gctgaaaaag aaaaactaga aaaatactta ggtggaataa aagacatgcc
     3061 tgaattacca ggtgcaatgt tcgtagttga cccaagaaaa gaaaacatag ctattcaaga
     3121 agctcataga ttaggtatac cagtagttgg tatagttgat actaactgtg acccagaaca
     3181 attagacttt gctataccag gaaatgatga cgctataaga gccgtaaaat taataactgg
     3241 tgctatggca acagctgtaa ttgaaggtag acaaggtgct gaggaagaag tagctgaaga
     3301 ccaagaataa taatttgaca attaaatggt aagggtcgcc cttaccattt ataatatgga
     3361 atagaataag taggaggaaa cttaaaaaat ggctaatata actgctcaaa tggtaaaaga
     3421 gttaagagaa agtacaggcg caggaatgat ggactgcaag aaagctttac aagaagctga
     3481 aggaaacatg gaaaaagcag tagatttatt aagagaaaaa ggattatcaa aagctgctaa
     3541 aaaagctggt agagttgctg ctgaaggtct agttgcaata gaaatgaatg atgataatac
     3601 agttgcttct atggtagaag ttaactcaga gacagatttc gttgctaaaa acgaagactt
     3661 caaagtgttc gttaaagatg ctgcttgtat ggcattagct actgataaag aagatatagc
     3721 ttctttatta ggtgaaactc ataaagaggg aataacttta caagaagttt taaataatag
     3781 agttgcaaaa ataggtgaga aattagactt tagaagattt gctaaagttg taactaatgg
     3841 acaagttgct ggatacattc acggtggtgg aaaaataggt gttcttgttg aaatggaaac
     3901 agaagctaga gatgctaaag ttttagaatt aggtaaagat gtagctatgc aagttgctgc
     3961 tatgaatcct aagtatgttt caagagatga agtagatgct gaatacatag cacatgaaac
     4021 agaagtatta actcaacaag ctttaaatga aggaaaacca gctaatatag ttgaaaaaat
     4081 ggttaaagga agattagaaa aagaattaaa agaggtttgt ttattagagc aaactttcgt
     4141 taaaaatcca gatataactg ttaaacaatt agttgctgat gttgctaagg cagtaggttc
     4201 tgatataaaa gttgttaaag ttgtgagatt cgaagttggt gaaggtatac aaaagagaga
     4261 agaaaacttt gcagaagaag ttgctaagca acttaagtaa taaccaaaga gagaacacgc
     4321 aggtgttctc ttttttaaaa aatagaaaaa attggatatg aaggattgaa ataggaggtt
     4381 tctgatggat aaaccaatgt acaaaagggt attgttaaaa ttaagtggag aagcattagc
     4441 aggagaaaga ggttttggta taaataatga tgtagttaat gatattgcta ttgctataaa
     4501 aaaaatacaa gaaataggtg ttgaagtagc tgtagtagta ggtggaggaa acttctggag
     4561 aggcagaacc agtgaaggaa tggacagaac tactgctgac tatataggaa tgttagctac
     4621 agttatgaat gcaatggcgc tacaggatgc actagaaaat atagatgttg ctacaagagt
     4681 tcaaactgct atagacatga gacaaattgc agaaccatat ataagaagaa gagcagttag
     4741 acacttagaa aaggaaagag ttgttatatt tggtgcagga acaggaaacc cttactttac
     4801 aacagataca actgctgctt tacgtgctgc tgagatggaa gcagaagtta tattgttagc
     4861 taaaaatgtt gatgcagtat atgacaagga tccaaaagta catgcagatg ctaagaaatt
     4921 tacagaatta agttacatgg aagttataca gaaagaatta aaagtaatgg attctacagc
     4981 tacatcttta tgtatggata ataaaattcc aataaaggta tttgagctta caacagagaa
     5041 tataataaga gcagtaaaag gcgaaaatat aggaactact gtaaaataat gaagaatgaa
     5101 ggaggagtaa aattatgaaa ctggaaatac ataagcaatt agaagagaaa atgaatggga
     5161 caattgatgc tttaaagttt gaatttggaa ctataagagc aggaagagct aatgcacaaa
     5221 tgctagacaa aataagagtt gattattatg gaactccaac tccaataaat caaataggtg
     5281 ctatatctgt accagaacca agaatattaa tgatatctcc ttgggataaa tctgctatgc
     5341 atgaaataga aaaagcgata gctaactcag acttaggatt aaatccatca aatgatggtg
     5401 aggttataag actttctgta cctgctttaa cagaagaaag aagaaaagaa ttagctaaaa
     5461 aagctagtaa agctgcagaa gaatttaaag ttagaataag aaatgaaaga agagacgcca
     5521 atgagaaaat taaaaagatg gaaaaaggcg gagaattaac tgaagatgaa ttaaaaaaag
     5581 cacaagatga agttcaaaaa atgactgata aatttataaa agaaatagat gcattattat
     5641 ctaaaaaaga aaaggacata atggaggtat aatattgaaa aaatattata accttttagg
     5701 tcttcatgta gatgaggtaa aacaatattt tgatgagcaa aatataaatt ataccgtaaa
     5761 atctattgaa ggtaaaaagg ataaagaaaa acttgtagtt cctagagtta taaaaatatc
     5821 tgagataggt gatagtgtag aactgataat cacatacttt tctgactcct tagtttaagg
     5881 agtcagaaca atattggagg caaaatatga ataacaacat tatatatgat atagacttaa
     5941 ataacatacc tactcatatt gctattataa tggatggaaa tggaagatgg gcaaaagcta
     6001 gatttcttcc aagaactgca ggacataagg ctggagtaga aactataaga gatatagtaa
     6061 aagaatgctc aaaattaggt gttaagcact taacattata tgcattttca acagaaaact
     6121 ggaaaagacc gaaacttgaa gttgacacac ttatgaactt attatctaca tacttaagaa
     6181 atgaaatagc tgaacttcac caaaacaatg taaaagtaac tgctatagga gatataagtg
     6241 ctttaccaaa aacttgtata agagaattaa actcagctaa ggaactgaca aaaaacaata
     6301 caggagttaa cttaaattta gcattaaact acggaagtag agcagatata aaaaatgctc
     6361 ttatagatat agtaaaaaat tgtgaaagtg gtaaaataga tataaacaat attgatgaag
     6421 atattataaa aaactattta agcacaaagt ctataccaga tccagacttg gtaataagaa
     6481 caagtggtga acaaagattg agtaactttt tactttggga agttgcttat tctgagtttt
     6541 actttactga tatacattgg cctgatttta aaaaagaaga actacagaag gctatatacg
     6601 tatatcaaag aagggataga agatttggag gacttaagta aggagattat tttatgctta
     6661 caagaattat tgcttcacta gctctggttc cattatttct atttgttgta tatggaggta
     6721 ttcctctata tatagctgag acagcaatag tttatattgc attgcatgag ttttataagg
     6781 catttaaaat aaaagatgta catccaatat tcattatagg atatttattt tctatttatt
     6841 tagctgtaaa aaatattttt aatttaccat tagaatatac ttatgcagta atttttattt
     6901 tatttttagc aagtataatt tatatgttga tgggcaaaaa caatgttata gatgtttcga
     6961 ttacgttttt aggagttttt tatataggag tatttttaga ttttataatt ataactataa
     7021 atggatttga aaaaggtagt atatatgtat ggcttatatt tgtgatatct tttatgacag
     7081 atatatttgc atattttagt ggttatttac ttggaaaaca taagctaatt cctaaagtta
     7141 gtcctaaaaa gactatagaa ggagctattg gaggaataat aggaagtaca ctttgttgta
     7201 ttttatttgg atatttattt ggcattgatt tgcttcaatt agcgataata ggaagtatag
     7261 gaagtgtaat agctcaatta ggagatttat ttgcatcttc tataaagaga tatgtaggga
     7321 taaaggatta tggaaagata atacctggtc atgggggtat attagataga tttgatagtg
     7381 ttatattagt tgcacctttt gtatatagtg cgattaaatt ttttattaga taaagattgg
     7441 ttggatttaa aagagcaatc tataattgct agtaatgaaa atagctatgt aacttttaaa
     7501 tgcagagata ttctgcagtt attagttaca tggctatttt cattgttcaa aaatttagaa
     7561 gaccttgggg aattgtataa gaataggtat tactttataa tagtatacta tatttgtagt
     7621 gagtatattt tttatactgt aactatcatt aaaaaatatt tttttgttta ataa
//
LOCUS       DAMJWC010000117         7628 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMJWC010000117 DAMJWC010000000
VERSION     DAMJWC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.122"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            86..1360
                     /locus_tag="PC503_003477"
     CDS             86..1360
                     /locus_tag="PC503_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2529427.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(1521..4562)
                     /locus_tag="PC503_003478"
     CDS             complement(1521..4562)
                     /locus_tag="PC503_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF2529428.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            4768..5067
                     /locus_tag="PC503_003479"
     CDS             4768..5067
                     /locus_tag="PC503_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF2529429.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(5306..7534)
                     /locus_tag="PC503_003480"
     CDS             complement(5306..7534)
                     /locus_tag="PC503_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF2529430.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         2639 a         1096 c         1078 g         2815 t
ORIGIN      
        1 tagaaagaat tggtattata taaagtaaga gaatatataa taagaaagaa tatttgattt
       61 tattggaaaa caaaagaaaa agaaggtgat tactatttct catataactg cgaagaatat
      121 gtataaaagt ttagaggaaa gaataaacaa gtttccacaa ggtgctccac catctgatac
      181 attatacaaa atactaaatg tactatatac agaacaagag gcgaagttag ttgctcagct
      241 tccaataaag cctttcagag taaaaacagc agctaaaatt tggagtgtaa gtgaaagtga
      301 agcatataga gtattggata aacttgctag taaggctctg atactagata tagaagataa
      361 taaagggaag aaatatataa tgcctcctcc aatggctggt ttttttgagt ttgccatgat
      421 gagaacgaga cacgatatag accaaaaact tttggcagag ctttactatc aatatatgaa
      481 tgtagaagaa gattttatca aagatttatt ttattcaaca gaaacgaagc ttggaagagt
      541 atacgttcaa gaggaagttt taactaatga taatgaggtt agtattttag attatgaaag
      601 ggctactcat ataattgatg aatcaactca tataggtata agtatgtgtt actgtagaca
      661 tagaatgcaa catgttggaa aagcttgtga tgctcctatg gatatatgta tgacgtttga
      721 caatgtagca aattctttaa taaataataa atttgcaaga cgtgtggata aaatagaatg
      781 taaagagcta cttcatcaag catatgaaca taacttagtt caatgtggag aaaatgttag
      841 gaaaggggtt acgtttatat gtaattgctg tggatgttgc tgtgaagcaa tggtagcagc
      901 taaaagattt ggaaatcttc atccagtaca gacaacaagt tttataccaa atataaacca
      961 tgaaaattgt gtaaagtgtg gtaaatgtat aactgcatgt ccaatagatg cgataagcaa
     1021 ggttaaggaa gatggtaaag aatatataaa aattgatgag gatagatgtt taggttgtgg
     1081 agtttgtgtt agaaattgcc ataaaaatag cattatgtta ttaaagagag atgaaaaaat
     1141 aataactcca gcaaattcag tacatagagc agttcttatg gcaattgaaa aagggcagtt
     1201 acaaaattta atttttgata ataatgctct ggctagtcat agagctatgg gagctatact
     1261 gtcagctata ttaaagcttg aaccagctaa aaagatttta gccagtaaac aattaaagtc
     1321 agtatattta gataaattgt taagtatgaa tgataaatag aaactaactt aaaaaaggca
     1381 aagttttaga cttatctata tcttaataaa cttatcattt aatatttaaa tttaattttt
     1441 acacatataa aacttataac ttaaataaaa aaaggctata ttcaattaat attacttgaa
     1501 tacagccttt tttagttatg ttaagctatt tcttttattt gcttaaatga gttttcattt
     1561 ccatttccac caatttgtgt tacagattta aatctcatag ttttaaatag ttctttttga
     1621 ttataatcta gtgagtttcc tactagcatt acaggagatt tagtttttcc agccaaaact
     1681 ccaacagata atccgtctat taaatcatct tgtttattca ttccattttt agcaacatat
     1741 aaattgtcta tcttagaatc cttgtaaaat tcttttatta cttttgcatt agtttcattt
     1801 ctagtgctac ctgatattct ctgtggattt tgaagtttac tttctatatt tttagaaact
     1861 gtatattctc caccgattac ataagattta tcaatctttt tgtttttaaa caagttattt
     1921 atttcagtta tattactatt ttcattagta agtattatag gcatatcatt ttgagctgat
     1981 acagctccaa tgcttactgc atcggctaat cctttttcgc cattaactac tgaaatcttt
     2041 gatatattgc taatattgtt caattcttta gcaatgttca tagaagtttg atatctatca
     2101 cttcctgaaa ttctagatac agagatattg tttgatttta tagtatctaa agatttttca
     2161 tttatagaag cttctccacc aactacatat acatttttaa cttttaatct ctttaattca
     2221 gccaaagttt tttcatttat ttgagagctt ccagtcaata atataggagc gtttttcttg
     2281 tatgcaaatg gtgttgcagc caaagcatct gcaattgctg aatcgtttat taaaactgca
     2341 ttttcagcat tttcccaacc tgcttgactt atcttaatag aagtttcata tctatcagtt
     2401 cctgtaagtg cacttgcatt tacttcatct tgatatgtaa cctcaaatct agcatttgga
     2461 cttcctaaga aaacaattac gcctcctttt ggcaatctaa ctctattgtt ctttgtaact
     2521 aaagaatagt ttacaggaac acctttatca tcataaacag caaaagctga attttgagga
     2581 agattaactt ctattttttt atttgcgata tcgtcaccaa tcttatacca ttttgcataa
     2641 ccattggatt ctagttcaca agtaaaagat ttttctgctg gcaaattagt tatagaatct
     2701 tcactaacat acgttagtgt tccaaaagat aaatactctg taccattttc tttatgaagt
     2761 ttaatgtcgg ataaatcacg acctattaca ccaggtattt ctataaaagc atttgagtta
     2821 ttctcatcca ttattttagt gttaactata taacctggag tttcatcaga aagagcaaga
     2881 gttgccttca cagaaccaaa catatagctt tgagaagtat atttttcatc tactagatag
     2941 taatctttac catttctttt tttccatgct tcttttacac tatttgatat attgttgtca
     3001 tctatctttt gagctacata gtataaactt gctgtctgac ctaatccagg gacatcatca
     3061 taagagctca tatttaaata tgtgatattg tttttttctt ttacaaattt tagacagctg
     3121 ttaccttttt cagatacaaa tctatcttga cctatgtata cgtatttatc ttcaggtcca
     3181 ttttctatat aaggagaaga tactgttaaa gtaccattat cattaacatc tacttttatc
     3241 atatttgaag aagcataaag accactattt tcttttagag agctaggcat tttaacttgt
     3301 tgtggtttac taaatgtttt atcaggtttt atttctttaa ttttaccttt ttcttttaat
     3361 gcagatagta agatttcttg tccaattatt tcattaagtt gactacttcc accagaagaa
     3421 agaactgcaa ctgccatatt ttcatctgga agaactataa gattactgtg gaataataaa
     3481 gagtctccac cttttgtaag agcttttaaa ttatactgat taaatggata agtgttgaca
     3541 caatcccacc ctaaaccata tccaagtata gagtcttctc cttcaggcca tagaccattt
     3601 aaatattctt tgttttccat agcttttact gaagcaggag aaagaatacc atttgaattt
     3661 ttcataaatg tttgtgcaaa tgtacataga ttttctgcac ttgaatataa accacctgca
     3721 cctatagcat taaggttatc ttgcggaact gcatcttccc aataaggcac gtatgctttt
     3781 gctagttttg aactatcaaa actattttct gtagtttttg tattttgtaa gttaagtgga
     3841 ttatttatgt atttatcaag aaaattagta aatgacatac cagatactct ttctactaaa
     3901 atttcagcta aagtaaatcc atcattacaa taaacggaaa aagctcctgg tttagctttt
     3961 aatctttgtt tttgtaattc ttttaagaaa ttatcatgac cataagaatc attgtctgct
     4021 aataaaatag tgtttttaaa actacttccc atcaaccctg atgaatgatt taataacatt
     4081 cttggagtga tttccttgta tctatcatca gccattttaa attcaggtat atactttaca
     4141 acaggagtat ctaaatttaa ttttccatca tcaaccaact tcataacagc tgttgtagta
     4201 aacattttac tgatagatgc gatactatac atattatcct tatttaagtt tttgttatcc
     4261 tgtttgctgt aaactccacc attaccagaa atctcaattt tgccattatc aatcaaagca
     4321 tattgagcac ttacagcacc atactttgat agcaaagttt ggattttctc tttagcaaga
     4381 gctttagttt ttgtgtaaga ttccgcgttt ttactataat catgtaattc tatatcagaa
     4441 ctttgatatt tttcggaatt atcttttgta ttatcagcaa aagtaatatt tggagcagca
     4501 gtaaataaca tactcaatac taatgtacta gataataatt tagagagcct ttgcttaaac
     4561 atattacatt acctctttcc ctttttaata atttataatt agcataacat tcttaattat
     4621 tttaatcaac agattattat caataaaaaa agcttttata agtatagctt tttatataac
     4681 agagaaaaat ataaaaataa tatttgttgt tgtataaaga ataaagggta taggtaatat
     4741 ataaataaaa tggaggaatt ttagacaatg tataagaata taaataaaaa gcaacttaaa
     4801 gaaatgatga aaaatgaaaa ggatgtttta ttattagatg taagaactaa agatgaattt
     4861 aaggaatata aaatagaaaa tgctataaat atatctttac aagagttaat caataatata
     4921 gatgaaattt acgattataa agataagaaa gtagtagttt attgcagaag tggtcataga
     4981 agtgttactg catgtaattt gttagctgaa gaaggttttg agcatttata taatttaaat
     5041 tcaggaataa ttgattatat gagttaaata atgtaagtta tacattaaat actatgtata
     5101 gctctgctta ttaagtagga atatatctaa atatttataa gataaattta ggaaagaacg
     5161 aattttttcg tttttttcta tgacagtttt tgtagtaaat attagttttt aagttggaaa
     5221 aaggtagtag ctttttagct actacctttt aatatgaact tagaatatta ttaaaaaaaa
     5281 tatatttaaa gacagaatta attttttaat gaccagttaa attactatcg ccgaatttat
     5341 cattaaatgg ttttataact ctatttatag gtccttttag aagtacattt aaacaaatag
     5401 acagaatcat aaatagtaat agaactagta tatctttagt tagatttgga gcatatatac
     5461 caccaactgc ttcccttgta gcacctattg cataggtaaa tggcattata gggtttattc
     5521 tttggaagaa tgtaggtgta acctgtatag ggaatgtacc accagaagaa ccaatctgaa
     5581 cgactaatag tactattgca attgcttttc ctacatttcc aaatacagaa actaaagaat
     5641 acactataaa gttaaatacc atactagtaa acataagcag aactatcaat aaaattggat
     5701 gttttgctgt tactcctaac aataatatat ctccagttcc tattataaaa ccttggacaa
     5761 gagctatact taaaaaagta aggcctcttc caaagtaaat ttcataaggt ttatagtttc
     5821 catgtacaga tgtagacaat agtgctgaaa taagtaatat accaacccat gtagaaagaa
     5881 cactataaaa tggtgtcatt gcagaaccat aattttcaat tggatataat ttctctgttt
     5941 tcacctcaac aggttctttt aagaaattag actttgtcaa tatatcactt tcaagcaagc
     6001 tgactaattt tttcatatct tcaccattac taattttgct taaagtatca atcaaatcat
     6061 ccaacattcc ttttgctaaa ggaagtcttt ctcttatcaa tgatatactt tcctgtgcat
     6121 ttcctgaaag ttttagagaa gtagtaagta tttcttcaac ctttggaagt tttgcttctg
     6181 ccttatctaa aacagtaatt atatcatttg ctacttttat actgtttgca aatatactat
     6241 ttataggttt tgatattttt gagtcaaaat tatttaaaat atttaaatta attcttccaa
     6301 taccatttga tagacttaaa acattattca aagcacttat agatggttgt tgtccagata
     6361 taactttgtt tttaatatca tttaatgttg atatagatga atctatttta ttgctagagt
     6421 cttcaagatt atctattaca tcatccaatc tattatttga tgtaagttgg tttaatttag
     6481 ttaaaaagtc caccaaagta tcgtttaaag attgcaaatt agaaagtttt tctgataaat
     6541 tatctatcaa cttaggtaca tcttcactgc cactatttac tgcatcaatt aaatttaatg
     6601 taagagaaga agcagaagat gaaaggtcaa ccattaaatt taagtcagac ttaataagag
     6661 gagaaagttc gtctaaatta tcatttgtat cctctaagaa tttttttaag tcacttgata
     6721 atagttttgt atcattcaga gtctttttaa ttgtaggtaa atcagattta atatctttaa
     6781 ctgtatcaga taattttgaa gtagcatcag aagctaaatc aacagtctta tttatatggt
     6841 caaatctctt ttgaaggtca ataagggaat tttcaacttt tgtcaatttt ggaagactgt
     6901 gttcaattcc tgcaccaact ccgtttgata taccaagaac gatttcacta actgttttta
     6961 ctatagtctg attaacctgt agttgtattg tagaagcacc tttatctgta atctttggtg
     7021 caactgcatt tattttttca ttaacagtat agataatttc gcctttttta acatcatctg
     7081 taattaaaga tgtcaaatct tttgtaaaat tttttggaat cttaagtgat gcataataag
     7141 tacctttttt aacaccttca agagcagttt tttcatctac aaactgccaa cctaaactct
     7201 tgttatcttt gagttgttca attaattggt ctcctacatt aatcttttgt cctgctattt
     7261 catttccttt atcttcattt gttactgcta caagcatatt agcagtgctt ccataagggt
     7321 cccaagatgc ctttatattg aaccaagcat acagagatgg taaaaaagca agacctaaaa
     7381 ctattacaag tacggcataa ttgccacgta tatcttttag gtcactttta aaaatttcta
     7441 atatattttt taaacccttt gaaggtctta aattcttgat attattccag tttaaaattt
     7501 cttttaaact attagttttt ttcaaatgtc tcacctccta aaatattttg ataaagaaaa
     7561 aagttagatt tataatcaat tttaaattat attacttttt acacaaatag taaagttaaa
     7621 attttgtc
//
LOCUS       DAMJWC010000118         7455 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMJWC010000118 DAMJWC010000000
VERSION     DAMJWC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7455
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.123"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            86..1063
                     /locus_tag="PC503_003481"
     CDS             86..1063
                     /locus_tag="PC503_003481"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF2529431.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1056..2024
                     /locus_tag="PC503_003482"
     CDS             1056..2024
                     /locus_tag="PC503_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF2529432.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2207..2797
                     /locus_tag="PC503_003483"
     CDS             2207..2797
                     /locus_tag="PC503_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2529433.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTATSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2816..3586
                     /locus_tag="PC503_003484"
     CDS             2816..3586
                     /locus_tag="PC503_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF2529434.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3723..4691
                     /gene="dusB"
                     /locus_tag="PC503_003485"
     CDS             3723..4691
                     /gene="dusB"
                     /locus_tag="PC503_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF2529435.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRATEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4800..5279
                     /gene="greA"
                     /locus_tag="PC503_003486"
     CDS             4800..5279
                     /gene="greA"
                     /locus_tag="PC503_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF2529436.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5294..6823
                     /gene="lysS"
                     /locus_tag="PC503_003487"
     CDS             5294..6823
                     /gene="lysS"
                     /locus_tag="PC503_003487"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF2529437.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7132..7326
                     /locus_tag="PC503_003488"
     CDS             7132..7326
                     /locus_tag="PC503_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529438.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2973 a          755 c         1508 g         2219 t
ORIGIN      
        1 aatagtatta aaagtatatt aataatgtat aattatttat tagaagaaaa taagtcatga
       61 aattatgtca tattagaggt gaaatatgag agataaaata atagagatta tattaaataa
      121 taaatctgaa tttatttcag gagaagaatt atcaaaacaa ttaggggtgt cacgtgcagc
      181 tatatggaaa catatgaaag ccttaaaaga agagggatat aatatagaat ctgtaaataa
      241 aaaagggtat cgattagcgg aaaatccaac tgatttatta agcccacaga atatttacta
      301 taaattagat acagagttta ttggaaaaaa tattgaacat cttgacacta tagattcaac
      361 aaatgaacat gctaaaagga tagctataaa tagtgtagat gggactgtga ttttaagtga
      421 acatcaagat atggggaaag gacgattggg aagaagatgg gattcaaaac ctcatgaagg
      481 aatctggatg agtattatat taaaaccaga tatggaacca ttcaaagccc catttataac
      541 tttaatagca ggagcaagtg taacgaaagc tttaaacaat ctaggagcaa atacattaat
      601 aaaatggcca aatgatgtta ttttaaatgg aaaaaaaata tgtggtatat taacagagtt
      661 atctgctgaa attgaaagaa caaattatgt tgttcttgga attggaataa atgttaaaat
      721 aatggatttt gaacaagaaa tagctgacaa agccacatca ttgtataaag aaggatatat
      781 gttatccaga gtagatattg ttaggaatgt attaactgaa tttgaaaaat tatatttaga
      841 ttatactgta aataattcca aagaaaaaac cttaaaaata tgtagagatt attctgcaat
      901 tatagataaa aatatatatg tattaaaagg agataataga gaactagtga aatgtttaga
      961 cataaatgaa gagggaaatt tattagttca aagaagtgat ggaagtataa aagaaattat
     1021 ttcaggtgaa gtttctataa gaggagaaaa aggatatgta taataatatt ttggatatag
     1081 aaggcttaaa ggttgggcag gttgaggata gaaatggtct tactgggtgc acagtagtaa
     1141 tatgtgaaga aggagctact tgcggtgttg atgtaagggg ctctgctcca ggtactagag
     1201 aaaccgattt attagaccct gtaaatatgg ttcaaaaagt tcatgcagta gttttggctg
     1261 gaggttctgc atatggtctt gaatccactt gtggtgtaag tagatactta gaagaaaaag
     1321 gaattggctt tgatgtaggt gtaggtaaag tgcctatagt tgtaggagca gttttatttg
     1381 atttaggagt agggagcttt aaatgtagac cagatttaaa gatgggttat agagcttgtg
     1441 aagttgcaaa tactgatatt ttaaatcaag gaaattatgg agcaggttgt ggagccactg
     1501 ttggaaagat aagaggtcag gaatatgcta tgaaaggcgg aataggtagc tattctataa
     1561 aattagataa tggtctaatt gtatctgcat taattgctgt aaatgctctt ggagatgttt
     1621 atgaaaatgg taaggttata gctggtgctt taaatgataa aaagacagaa acaattgata
     1681 catataaatt aatgaaacaa ggtgaaagta aaggtggatt tagtgtagat aatactacaa
     1741 ttgggataat tgcaacaaat gctaagttaa ccaaagctgg atgtaaaaag atatctcaaa
     1801 tgggacatga tggatatgct aagtctattt ttcctatcca tacacctcat gatggagata
     1861 caatattcac aatatcaaca ggagaaatag aagcagatat aacattagta ggttcattgg
     1921 ctgtagaggt tgtggaaaaa agtataataa atgcagtaaa aaaagcggat agtgtagaaa
     1981 atataatggc atataaagat atagtaaaaa aacgagaaat atgatgaaat tagcatattt
     2041 ttcttgtcaa attgttgaca atggcaactc atcttgataa aattattctt gttagagcgg
     2101 gcatcctaca atggtagctt gactcatagt tataagaaaa aacgaaaaaa attaaaaaat
     2161 taagtagtcc ggcatcttaa tgagctggaa cggaggtgta ttttttatga tgaacacaag
     2221 tgcatcagta agaaaagtaa atgtaagaaa gatgactata ataggagtac tatcagctat
     2281 ttctattatg ctatctatga ctccattggg atttattcca gttggaccta caaaagcaac
     2341 tataatgcac ataccagtta ttattggagc tattatggaa ggaccaatag ttggggcagc
     2401 aataggattt atatttggga tatcaagtct cttaaatgct ataacaaacc caacagcaac
     2461 atcttttgtt tttataaatc cattagtttc aatattacca agagttatga taggtgtatt
     2521 agcttattat gtatatcagt taataattaa ggctacaaat aaggtataca tatcaggttt
     2581 aattacaggg gcaataggtt ctctgttaaa tacagctgga gttttaggaa tgatatatgt
     2641 cttatatgct gacaagtatc ttcatgcaat gggtaaaagt ggttcagcag gaaaagtaat
     2701 aatggctctt gccgcagcaa atggggtgcc agaagcaata gtaggggctt tagtagtagc
     2761 tgctgttgcc actgtactta agaaaagcaa aaaatagaaa gaaggttaat gacatatgct
     2821 tctagtattt gatgttggaa atactaatat ggttttaggt atatataaag gtgacaaatt
     2881 agttaattac tggagaatta aaacagatag ggaaaaaacg tctgatgaat atggaatcct
     2941 gataagtaac ctatttgatt atgataatgt gaatataagt gatattgatg atgttataat
     3001 atcatctgta gttccgaatg ttatgcattc tcttgaaaac ttttgtataa agtactgtaa
     3061 aaaacagcca ttaatagtag gtccaggcat aaaaacaggt ctaaatataa aatatgataa
     3121 tccaaaacaa gttggggcag atagaatagt taatgctgta gcagggatag aaaagtatgg
     3181 agcaccaagt atacttgttg attttggaac agcaactaca ttttgtgcta tctctgaaaa
     3241 aggtgaatat ttgggtggaa caatagcacc aggaataaaa atatctagtg aggcgttatt
     3301 tcaaagtgcg tctaaattac ctagagtaga attagctaag ccaggtatga ctatttgtaa
     3361 gagtactgta tcagccatgc aatctggaat aatttatgga tatgttggtt tagttgacaa
     3421 aataataagt atgatgaaga aagaattgaa ttgtgatgat gttaaggtta tagctacagg
     3481 tggattagct aaactgattg cttcagagac gaaaagtata gattatgtag atggtttttt
     3541 aacactagaa ggattgagaa taatatatga aaaaaaccaa gaataattaa tatacaggga
     3601 attgggttat atatccaatt ccctttttat gatagatttc tagctatatg tggtatatta
     3661 taatgaggaa ataagaattt aaagttaaat cacaaaataa aggcaaaaat aggagaaaaa
     3721 caatgaaaat aggaaattta gaattgaaaa ataaagtttt tctatcacct atggcaggtg
     3781 taacagacct tccatttaga ttaatttgta aagaacaagg atgtgggctt ttatatacag
     3841 aaatgataaa tggtaaggca ctttgctatg atgatgaaaa tactaaaaaa atgcttaaga
     3901 tagaagagga agaacatcct gtagcagttc agatattcgg ttcagaacca gagtttatgg
     3961 gaagagcaac agagataatg aatgattatt caaatgagat tctcgatata aatatggggt
     4021 gtccagctcc aaaagtagtt aaaaatggag atggttcagc acttatgaaa aatcctaagc
     4081 ttgcagaaga ggtattgagg gcagtagtga agaactcaaa aaagccagtg actttaaaga
     4141 ttcgaaaagg ctgggatgat aatagtgtaa atgctgttga aatagcaaag atagcagagg
     4201 attgtggaat aagtgcttta gcaatacatg gaagaactag agaacagttt tatacaggca
     4261 aagcagactg ggatataatt gcagagatta agaaaaattt gagtatacct gttataggaa
     4321 atggtgatgt atttacaata gaagattcaa taaatatgtt agacaaaact ggttgtgatg
     4381 ctataatgat aggtaggggt gctcaaggta acccttggat atttaaaaga ataaaccatt
     4441 atatgaatac aggcgagatt ttgccagagc caactcttaa cgaaaaaata agtactgcca
     4501 ttaagcattt aaaacttgca gtagaagaac atggagagta tgtagctgta agggaaatga
     4561 gaaaacacat cgcttggtat ttaaaaggac ttagaaactc tgcaaaatta agggatgaaa
     4621 ttaacaaaat agaagactat caagaagttg tgtcgaaatt ggagtactat atggaagact
     4681 ccttgacata aaaataatag tgacttataa tatagcgcat aaattaaaaa aagattataa
     4741 aatttttaaa atataattag gaaaattcct aagaaatttg tgaaggagtt gtatttataa
     4801 tggaagaaaa taaagagttt ttattgacac aagagggata tgataaatta gaagaagaat
     4861 tagaaaactt aaaggttgta aagagaaaag aagttgcaga gagaataaaa gttgctatat
     4921 cttttggtga tttatctgaa aatgctgagt atgatgaagc taaaaaggaa caagcacaag
     4981 ttgaagaaag aattttaaaa ttagaaaata tggttagaaa agctgttatc atagatgaaa
     5041 gcaaaataga ccttaatgtt gttacaatag gatcaatagt taaagttaag gatttagaat
     5101 ttgatgaaga ggttgaatat actatagttg gttcgacaga agcagaccca tatgatggta
     5161 aaatatcaaa cgaatctcct gtagggaaag cacttttagg tagagctgcg aaagaagttg
     5221 tggaagtgca agttcctgat ggagttgcta agtttgaaat attagaaata agaagataat
     5281 ttggaggaaa aaaatgaaaa ataatcaaca aagcaatgaa gaagcgcaaa ttcaagaaga
     5341 ccttagtgaa gtacttcaag taagaagaga taaactaaaa aaattacaag agtcaggtag
     5401 agatcctttt aaagaaagta gatatgatag aactcattat tctatggata taaaagataa
     5461 ctttgattct cttgagggta aaactacaaa aatagcagga cgtataatga gcaagagaat
     5521 acaagggaaa gctggcttta tagatattca agaccaagag ggaagaatcc aatcttatgt
     5581 aagactagat gctataggag aggaagaata tagtgtattt tcaacatatg atattggaga
     5641 tatagttgga attgaaggag aaatctttaa aactaaaaaa ggtgaaatat ctgtaaaggc
     5701 taaatctgta gtattactat gtaaatcttt acaagtttta ccagaaaaat atcatggatt
     5761 aaaagaccaa gaactaagat atagacaaag atatgttgac ttaatagtaa atccagaagt
     5821 aaaaaatgct tttttaatta gaacaaaagc attaaaagca ttaagagcat acttagatga
     5881 tagaggattt ttagaagttg agactccaat attaaatact atagcaggtg gggcaaatgc
     5941 tagaccattt ataactaatc ataatacttt acatatacca atgtatttaa gaatagcgaa
     6001 tgaattgtat ttaaaaagac ttattgttgg tggatttgat aaagtttatg aaatgggaag
     6061 aatgtttaga aatgaaggta tggatttaaa acataatcct gaatatactg caatagaatt
     6121 atatcaagca tatgcagact atactgatat gatggaaata acagaaaatg ttattgcaca
     6181 tatggctgaa gttgctacag gaagtatgat agttaactat caaggaacag aaataaactt
     6241 tacaccacct tggaaaagaa tgagtatgga agattgtgtt aaagaatatt ctggtgtaga
     6301 tttttctact ataaatacag atgaagaggc actagaagtt gctagagaaa aaggtataga
     6361 gataaaacct ggaatgagaa gaggagaagt aataaatgct ttctttgaag aatttggaga
     6421 agataaatta atccaaccaa catttataac tcaccatcca gttgaagtat ctccattatc
     6481 taagagaaat gttgaagacc caagaagaac tgatagattt gaggcatttg ctaataagtg
     6541 ggagttagct aatgcatttt ctgaacttaa tgaccctatt gaccaaaaag gaagatttat
     6601 agaccaattg agaaaaagag aattaggtga tgatgaagct tttgaaatgg atgaagattt
     6661 cttaaaagca ttagaggtag gtctacctcc tacaggagga ctaggaatag gtatagatag
     6721 agtaattatg ttattaacta actctccatc tataagagat gtattattat tcccgactat
     6781 gaaacctatt gataacaatc caaataaaga agaagaaaac taagaaatat tagcattcta
     6841 ctaagtttta aataaagttt agctattaaa ttatcaataa atagctaaat tttatttaaa
     6901 atgtcagtgt ggaatgcttt ttatatgctt caaagattct tttagatatt taatttataa
     6961 attaccaaca aacgttagaa attgatatta gtttttgttg attgagactt tatatttaga
     7021 aaatatgatt gaaagtaatt tattatgaaa atatttagaa taatttatga gaaggtaaaa
     7081 agaataattt atgagaatac tatatataaa aaattattgg gggaatgtct gatgtttcaa
     7141 gtaattaatt ttttatgttt attttgtgtt ggatttttgg ttcttgatgt tatgatatat
     7201 ttttgtaagg atgcaatgga tatttttgag ggtacaacta atgttaataa agttaagagt
     7261 ataaatgttt gggcagatag agtgagagct aattcatatt cttatgaaaa taaaattgca
     7321 aaataggtaa aattatatat gcatgtattg tttgtaatat caagggttat atctattagt
     7381 tttaattata tttattaaaa aaaccaaaag ttataacctt ttttaaaata aaaaacaaaa
     7441 aaagtattga cgaaa
//
LOCUS       DAMJWC010000119         7330 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMJWC010000119 DAMJWC010000000
VERSION     DAMJWC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7330
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.124"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            143..3322
                     /locus_tag="PC503_003489"
     CDS             143..3322
                     /locus_tag="PC503_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2529439.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            complement(3607..4371)
                     /locus_tag="PC503_003490"
     CDS             complement(3607..4371)
                     /locus_tag="PC503_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2529440.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4527..4760)
                     /locus_tag="PC503_003491"
     CDS             complement(4527..4760)
                     /locus_tag="PC503_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529441.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            complement(4834..6327)
                     /locus_tag="PC503_003492"
     CDS             complement(4834..6327)
                     /locus_tag="PC503_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2529442.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6655..7197)
                     /locus_tag="PC503_003493"
     CDS             complement(6655..7197)
                     /locus_tag="PC503_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2529443.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2682 a         1064 c          820 g         2764 t
ORIGIN      
        1 aaatctaata gtaaattgtt atttacacat atatcgtgat agataaaagc tattcatatc
       61 tgccttaatt ttagtcttaa atttagagtg taaattgaat gcatttagat tataatatat
      121 acagtgaggt aaggtgaata atatgaaaat agatatgata tataaactaa taagaagaaa
      181 tacagaacca tcaagatggt caagaggtgt aaaatattat actaatcaat tagttgatta
      241 tatagacata gatattgatg acctacaaaa taatctgttg acatttcgtg gtggagtcaa
      301 ttctgaagat aattatagct tttattttaa ttcaataact atagatataa agcactttaa
      361 gataattgaa aatgattgta gttgcgctga ctgtcaatca aagggcaaaa gtatttttat
      421 atgtaagcat atagttgcta ttgtgataaa aagcttaaaa caaataaaaa ataaaaaaga
      481 tgttcctcct attctaatag atatattagg tgcagataag gataagcttt ctaatacaaa
      541 ttctaaaacc agcttagatt taagcaagca attactttct ttgttagaca atactaaaag
      601 agaaagggtt aatttagatg tattgataaa tgtggattca aataaagcaa ttgctgaatt
      661 taaaatagga attaataaaa tgtacatttt aaaaaacatt actgaatttg catattcaaa
      721 acttaatgga tatgaattag attttgggaa gaaatttact tacaacccca acactcatta
      781 ttttgctgat gaagatgaga agttagtaga tattatagaa gaatatggga caaatctttc
      841 atacaacttt tcttcatcac attcaaaaaa atttatggag ataaatgcaa gctctttaaa
      901 acaattttta aatgctatta agtacaagga ttttaccctt attttttcta aagaggaata
      961 tcatccaaag atattaaatg atactctacc tgtaaggttt gattttaaaa atatagaaga
     1021 taaaatagtc ttatattcta aagattcact acctgttcca cttactaaaa aaaatgatgt
     1081 acttttatat gatggcaata tctatttatt atcacataaa aaagctcatg attattcaaa
     1141 aatatatcaa atattatcaa agactaaaga gttaaaattt gataaagagg attctaagga
     1201 tgttttagga ttgctagttc ctagattaaa atctatatct caagaagttc atttagatga
     1261 taacataaaa aataatataa caaaagattt taaatctgag ttctactttg atatgattga
     1321 tggcaacata tgttgtgatg taaagtatat atatgatgat gaagataaaa aatttgtgct
     1381 ccccaacata caaaaggaag ctactattga aaataaactt acttcttcac aatttacaaa
     1441 ggaaaataat cattatgtgt ttaaaggaac tgaccatgac ctatttacat ttttagattt
     1501 acaattagaa tctctaaagg aatttggaga tatatattat tctgagaagt ttaaattgaa
     1561 aaaaatatat aacgcttcat caattcaagc ttcaatcaat cagactaacc agaattacct
     1621 agaatttaat tttaatatat ctgatataaa tccaaaagag tacaaggata ttttgaaagc
     1681 ttttcaagaa aaacgtactt tttataaact taaagatgga aactttatag atttatcaga
     1741 aagagaaaca aaagattttt ttgaattagt tgaaaatcta gatataatgg ataaatcaaa
     1801 aaataataaa attcataaaa ataaagctct atatataaat gatgtaatac gtagtaaaaa
     1861 tttaaagttt atagatggta aaaaagaact agacagtata tgtgaaaaat ttagaaattt
     1921 tgatagcata aatttagaaa ttcccgcaaa tttaaatgca aaccttcgtg actatcaaat
     1981 aaatggcctc aattggttta aagttttaga ttattataaa tttggtggta tattagctga
     2041 tgaaatgggt cttggtaaaa caatacagac tattgcattt ttattatcat tatctaataa
     2101 aaaaagtctt attgttacac cgacatcact catttataat tggaaaaatg aatttgaaaa
     2161 gtttgctcca gatataaaag ttttattgat acatggaaat aaaagagata gagaaaaatg
     2221 ttttatggaa ttagaaaatt ttgatgtaat acttacaaca tatggtactc ttagaaatga
     2281 tttagacaaa tatagtgaaa taaagtttga ttattgtata ttagacgaag ctcaaaatat
     2341 aaaaaatcca gtggctttag taactgagtc tgtaaaaagt ataaatgcag aaaataaatt
     2401 tgcactcact ggtacaccta tggaaaataa tctactagaa ttatggtcta tatttgattt
     2461 tataatgcct ggctatctat atagtaaagc aaagtttcag gaattgttta taaataaaga
     2521 agataatgtt aaaaacctga aaaaattgat aaaacctttt attcttagaa gaagtaaaaa
     2581 acaagttatg aaagaacttc cagataagat tgaaaaaaac ttttttgttg aattgaataa
     2641 agagcagaaa aagatatata gtgtatattc aaaagatata caagataaaa tgaaagataa
     2701 aaatctaaag aaagataaaa tagttatatt ctcttattta actaaactaa gacaactttg
     2761 tttagaccca agtatagtag taaaagatta caataaaaaa agttcaaaaa ttgaaacatg
     2821 tttagaaata cttagggata gtataaacga aaaccacaaa atattattgt tttcacaatt
     2881 tacttctgtg cttaagaaca taagtaagga acttgataag tataaaatta aataccatta
     2941 tatagatggt aaaactaatg ccaaagaaag acttgaactt gtagatgagt tcaataatag
     3001 tatggataaa aaagtttttt taatatcttt aaaagcaggc ggaactggtt taaatcttac
     3061 atctgctgac atggtaattc actttgaccc atggtggaat ccatcagtag aaaatcaagc
     3121 tagtgataga gctcatagat ttggtcaaaa aaattcagta caagttataa aattgattgc
     3181 taaagggact atagaagaaa aaataataaa attacaagaa agtaaaaaag agcttataaa
     3241 tcaatttata aatggagaac tttctaatga aggtgtatta aaaagtctat ctgatgagga
     3301 gataataaac ttatttaact aaattattta atcctacagc ttaactatat gaatttgttc
     3361 taacatttat atagttaagc taaaatatct gaataaataa aatttaatat tgttatttaa
     3421 tcccaacttt acaatctaat gatatctctt tctatacata ttgcatatac aaatgtaata
     3481 acttgactat tagaatattt tgttttaaca atcctatttc atcataataa tgaagtatat
     3541 gtacactcac ttttgtaagt tttgcaatcc attttacagt tttcattatt gtaaattttg
     3601 gttaaattat tcctctaaaa atttctttgc tacatttgaa aaatctaatc cattcgataa
     3661 aattgcagga tgaccacctt tatcaaacaa atacatttta ccatttttaa tcttttcaag
     3721 aagtaatgaa aaagtatttt caaaaaaatc actagatatt agagatacaa actcatcttc
     3781 tctacttcct gttaaaagca cctctggttg catagtttct agaggcttat gaaaaaactt
     3841 tcctatagtt ttataatgtt caaaaatagc ttctgtatca ttatctacaa ctttttccca
     3901 gttttctcct tgattataaa tataaaaagc ttttgcacca tcatcttgct tagatgcttc
     3961 acgctctatt ttcacatttt gtacaaatga ctctagagga acttctcctt caaaactatc
     4021 tgcaattacc ttattcacta aatcaggtct ctcaagtgca acatttaatg caacaagagc
     4081 tcctccacta ctaccaatta tgtttacttt tttatagttc attgcttcta aaaaacatat
     4141 cacttgcata gcctcatcaa accataagtc agcagaaaat ttatcgacca tttgagattt
     4201 tccatgacct acaaaatcaa ttaatattac tttatattca tctttataaa aattgattat
     4261 atcattaaac atcttggaag aggctgtatt tccatgtaaa aaaagtaatg gtgtaccatc
     4321 cccaatttca ttatagtagc actgtttgtc gttatagtta aaatatgcca tatatttccc
     4381 ccctttaata tccctatagg tatatattta ttacttatat ttaaaatgac tattccctta
     4441 gccacttaaa aatagtataa cttagaatgt agataaaatc aacattcctt gctaatttat
     4501 ctattgtttg tctaatttat tataatttaa cttctgtaaa atttcttttt tgtacgaaaa
     4561 tattccttcc atttacaaca atcattcaaa tgaagtataa catgacgagt aggaggcata
     4621 agcaaaattc cagcaatatc tttattcccc caaaagtcca acaaccaaat agaatcttca
     4681 tgctttatta ctcctccagt caccaaaatc ctttctaagt caattggaga gacctttcgt
     4741 ttcatatctt cagctttcaa atccttaaca acttctattg tgttttttgc aacttcattt
     4801 cgataacaaa gcaattcatc aatattgact aaattatcgt atatctcttt tcactttaac
     4861 catttttttc tttataggta tctccttata tttttttaat atcaaatctc ccttataatt
     4921 taatatatct acatatgaac ataaatcttg aacttcaatt acacctatat catcattagt
     4981 tatacctttt atattactaa atgcaccaac tatatctaaa actcttattt tcttcttctt
     5041 accagcattt aaatataatt taacaacttc actttctata tttagtttta tatctttact
     5101 tttgtaagaa tttttatcaa ctttttttct ctttgatact ttttttagga ttccttttga
     5161 atattcttca aacaaaactt tgccatgtgt aattctactt ttttctatat cttttaattc
     5221 atttatttta tatcctatat acgtttctat attctctata tatttttcat ccttttcagt
     5281 tactatagta attgcctttc cactatttcc ttttctccca gttctaccta ttctatgtat
     5341 atagttttct ttatcttgtg gcacatcata atttattact aaagaaatat catcaatatg
     5401 tattcctctg gacgctacat cactactaac taatatatta aatttttggt ttttaaaatc
     5461 cttaattaca aaaattcttc tttcttgtga taaatctgca tgtaactctc ttattaaaaa
     5521 accctcttta ctcatcttgt tatataattt agatactttc tctttggtat tacaaaatat
     5581 tatcacactc tttggatttt cgctgtatat taattctttt aaaaggatgt acttctctct
     5641 tccatttgcc ttgattattt tgtcatctat ttgtcttgtt ttttgattag tatcgctctc
     5701 attttcttct atatttataa cactgtaatc tagcatatat ttttcacata tatattttat
     5761 ctcttcatct attgtagctg aaaaaagact tactattttc tccttaggta aatttaataa
     5821 tattttttcc atttgttcaa caaaaccttt attaaacatt ttatctgcct catctattac
     5881 taaatacttt acattttcca acttaataga acctctattt atatggtcaa gtattctgcc
     5941 tggagtagct acaacaatat gaaccctttg tttcaattca gctatttggt cttttataga
     6001 ttgtttgcca aatatagcac tacatctcac cttctttagt ctccctatat ctgatatctc
     6061 atcttttact tgcaaggcta attctcttgt tggaaccact ataagagctt gaatattatt
     6121 gtaatctaca tttatattct cgcataaagg tattgcaaaa cttgctgtct ttccacttcc
     6181 tgtttttgac ctaactacta agttttgacc ttttaataat tttggaataa cttctctttg
     6241 tactctagaa ggtatattat atcctaaact cttcaatgac ttaagtatct tttcatttaa
     6301 cttaaatttt tcaaatgtat atttcatata ttaccacctt attatattta tcttatctat
     6361 atatttttct acattatatt attataatac aaggttctac tatttttata ttatttatta
     6421 gactgaagat aaaagtatat actctataaa cctatagttt agtagcaaat taattaaatt
     6481 tttatattta aatacctcct taaatatact gataaatcaa tattttcaag gaggtatctc
     6541 ttgtcaataa tcaaactaat ctatcttttg aaagtttaaa ttatactaat acattgtatt
     6601 tttatttata tctaatatta aaaggtatta atcaatacct aaatcaccat aatctcacat
     6661 atttatatct ttattcaata taccttctgt aatcaatcgt gctatataat cataacctga
     6721 ttcatttgct ttgttacaat cattcacatt atcacagaaa aaactttcaa tctgtattgc
     6781 aactggattt gtatttctca atatatataa attttctctt tttttagctc ctctattttc
     6841 aaataattct ccaagtctat tagatactct tttagcatat tctaatcctt cagtgccata
     6901 gtaaagcact tctgtaccac attgtgttcc atcagcttta tttaaatgta gctctactaa
     6961 taaatcgtat ttaccactgt ttacttttgg aactctatag aaaaattctt ctctttctga
     7021 cataaagtgc ctttctggac aaattattac atctactgta ttaccttgac ttataagcat
     7081 ctcagctaac ataggagcta attttttatt ataattgtat tcatcaacta taccatttac
     7141 acctgtactt ttaccacctt ttagtatact atgacctact gttatgcata ttttcattta
     7201 cttttttcac cttcttttaa gccaattttt atataatagt aatataattt taaagttatt
     7261 actaataata atatattaat tgaagaaggt aaaagttctc cgtgattatc atttttttaa
     7321 catatttgtc
//
LOCUS       DAMJWC010000120         7320 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMJWC010000120 DAMJWC010000000
VERSION     DAMJWC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.125"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            607..1116
                     /locus_tag="PC503_003494"
     CDS             607..1116
                     /locus_tag="PC503_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF2529444.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1144..1338
                     /gene="rpmI"
                     /locus_tag="PC503_003495"
     CDS             1144..1338
                     /gene="rpmI"
                     /locus_tag="PC503_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF2529445.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1394..1750
                     /gene="rplT"
                     /locus_tag="PC503_003496"
     CDS             1394..1750
                     /gene="rplT"
                     /locus_tag="PC503_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF2529446.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            2060..2605
                     /locus_tag="PC503_003497"
     CDS             2060..2605
                     /locus_tag="PC503_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529447.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKKDEGK"
     gene            3040..4965
                     /locus_tag="PC503_003498"
     CDS             3040..4965
                     /locus_tag="PC503_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2529448.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5366..7270
                     /locus_tag="PC503_003499"
     CDS             5366..7270
                     /locus_tag="PC503_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2529449.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3076 a          720 c         1383 g         2141 t
ORIGIN      
        1 gttatgtagt atagtaacat attagaatat aatgtaggat ttgttatgta gtatagtagc
       61 atattagaat ataatgtagg acttgttatg tagtatagta acatattaga atataatgta
      121 ggatttgtta tgtagtataa tagtatatta gagtacaata tagaatttgt tatgtagtat
      181 agtagtatat tagaatacaa tatagaattt gttgggtagt atagtgttat attagaatac
      241 aatataggat ttgttatgta gaatatatag agtcatgtag aatatacata tataaaagga
      301 ttttgggtat aaatttaaaa attaatagca aaatgagtag tatagacata taattagtag
      361 taggaagtaa ttaaattttt cctaaacaaa aaaaatagtt gcaaataatt tgattaagtg
      421 atatagtaaa taaggtaaga ataaaacaaa gaagaagtcc gcttctcacc ttacgccgga
      481 ggttagtaag gtaaatataa gttaaagctt aattttaatt taagtttgtt taaatttggt
      541 aacttatatt gcggatgatt acgtcatccg ctttttattt tataaaaatt ttggaggtgt
      601 cctacaatta gcaaagaatt agcaatcaat gaacaaataa aagataagga aataagagtc
      661 ctttcaccaa caggtgaaca acttggagta atgcctacta aagaagctca agcaatggct
      721 aatagcaaaa acttagattt ggttcaaatc tcgccgaatg caaatccacc agtatgtaag
      781 ataatggatt atggaaagtt tagatatgag caagcgagaa aagagaaaga agctaagaaa
      841 aaacaaaaaa ctatagttgt aaaagaagta agacttagac caggtattga acaaaatgat
      901 ttaaatacga aagctaataa tgctataaag ttccttaaaa aaggggataa agtcaaagtt
      961 gaacttagat ttagaggaag agaattagga cataaagaca taggtaaaga agttatgctt
     1021 aagtttttag atataataaa agagtttgga gaaccaacaa aagcccctgc atttgagggt
     1081 aataatatgg ttgtaattat agatccaaaa aaatagatga ttaactgaga ggaggaattt
     1141 gtcatgccta aaatgaaaac tcatagaggt gcagcaaaga gattaaagaa aacaggaact
     1201 ggaaagttaa agagagctaa agcttttaaa aaacatatat taactaaaaa atctgcaaaa
     1261 actaaaatga acttaagaaa atcaacttta gtaagtgatg gagatgctaa gagaatagca
     1321 caattattac catactaaga tacagattgt aaataataac tatagaagag ggatataaaa
     1381 ggaggtcata acgatggcaa gagttaaaaa agctatgaac gctcgtaaaa agcataagaa
     1441 aatattaaaa cttgcaaaag gattcagagg atctagaagc aaattatata gaccagcaaa
     1501 tacattcgta atgaaagcat taaaaaatgc ttatatagga agaaagttaa agaagagaga
     1561 cttcagaaaa ctttggatac aaagaataaa tgcagctgct agaatgaatg gaatatctta
     1621 ttcaagatta atgaatggat taaaattatc tggtgttgaa gttaacagaa aaatgttatc
     1681 tgaaatggct atacaagacc cagaaggatt tgcaaaatta gcagaagttg ctaaagcaaa
     1741 attagcttag tattgaatca tgagatgtaa agtctttgag ttatataaat aattcaagga
     1801 cttttttatt ttttgaaaaa tacttattag tgtcatgtac aaccaatttt ataatgataa
     1861 ataaaataag caatacaata gaattttatg agatttatta taagaattgt tacaattatt
     1921 tatgatagct ataaaaagtc atagtaaaaa tgatattgat gtatgttgat atatgtataa
     1981 agtttccaat caatcttgaa ttaatattat caacatgata atattatctt attaataata
     2041 taaataaggg ggacataata tgaatgaaaa actaatggat tgttttgtaa acccaattaa
     2101 atgcaagtta ttgattgaaa ttttttcaaa taatcgaact acagctaaac aattaggaga
     2161 aaaatttcaa gatatatcaa aggcaacact ttatcgttac cttaataaaa tgttgaaaga
     2221 tgatattata aaagtggttg aagaaaataa aataagggga actgttgaaa aagtatatgc
     2281 tatgaagtta gatatagctg atgatgtgaa caaaattata gatgagaact ctggagaaga
     2341 atatgctcaa ctgtttactc aatatatgat gggattttta agagaatttt atgaatacgc
     2401 tgaaagaaag gaaaaggata tcctaaaaga tggttcagga ttttctgtct gtccagtata
     2461 tgctagtatt gatgagatag ttgaagtgag taaaaaaatt gctagtatac tagaacctct
     2521 aagaaataac tcacatgaag aaggtagaag aatgcattct ataggagtga taattactcc
     2581 acctaaaaag gatgaaggga aataaatctg atttacatgg ggtagagcca atttatacag
     2641 ggaatcgttt tatgatttac atatgtatcc agagcaaagt atctctgctt ggattgtact
     2701 tcattgtacc atttcatcca atgacttgga gtggtacaat gaagtttttt aatttttcat
     2761 attaatgcta aagaaatgaa ctttagacca catatgcaat taggttgcat tatacaatta
     2821 gaccacatat acaaaataaa aatcagtatt tttatagcag ataaattgac tgtcattctt
     2881 cttaaaaatc atctattagt tattgttagc atattgaaag aaattatagt aatctattga
     2941 ataaatgaat attgcctata atcatataaa ctgctatagt ttaaaataaa gcaggacgtt
     3001 aaattttata gtaatctaaa aatttaagag ggggatttta tgaaaataaa atttgttatt
     3061 atgccattgg tgatattttt aatggtatta tttgtggggt gtcaaagtac aaaagataca
     3121 gaagttaaag caaaagatac agaaattaaa atattaggga caggtgattt acattcaatt
     3181 ttgacagact ctatggtttc gtatgtaaat gaggaaaggg aaaagaataa aaatctgctt
     3241 atggtagatg cgggagattt ctatggtaca caaagtagag aaatgtggga atggtcttct
     3301 ggaaaaaagt taattaatat taaaagaaat ggtagagcag agtatgatga cataattaag
     3361 agtagtaaag atgaagtacc tatagttaaa gatatggcaa agttgaaata tgatgctgta
     3421 gttttgggag ataatgaatt tgtttcaaat gataagcaaa gtcttgataa actggtttct
     3481 gattttaaaa ataataatat gccattggta tcagcaaata tatatgaaca atctggagaa
     3541 aattatgtac aaccatatgt aatgaaaaat attaagacag atgagggcaa tgtaaaagtt
     3601 ggaatactag gtcttactat aaaagaagta ggggaaaccc ttggtcttga ggattttgaa
     3661 aaggataaaa aagctagaga gcttggagaa caagctgatt acaaaggaaa attatatgca
     3721 aatgatttag tagaagatgc aaaaaaatgg ataaaagtta tggaaaaaga aagtccagac
     3781 ataatagttg cagttgtaca ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat
     3841 agaataaaag agttagcaac tacagtggat ggaatagatg caattgtagc tggtcatact
     3901 catgaaaaaa tagatgaaca caaatataaa aataaatctg gagatgaagt aattgttaca
     3961 caaccaggtt ggcatggaga tagagtatca gagattaatt tcaaactaaa taaagagaat
     4021 ggaaagtggg acataaagga aaagtctagt aaattaaaaa taattgataa agaagtaagt
     4081 atagttgcta ctgcagattt acattcacat ttctctgata aattaacagt tgaccttgtt
     4141 aatgaacgaa gtaacccaat tgaacctgtt gtagtagatg caggcgactt cttagaccct
     4201 caaacagatg aaatgactca atggtataaa gagtggaaaa gtataagaga taataatagt
     4261 gataaaacga ttagtagatg cccaatggtc atggatatga atcagggaat gtatgatgca
     4321 gtagtacttg gaaatcatga atttgtatct gaaaaagatg aattttggtc agatgaacgc
     4381 cttttagatg ctgttataga ggattttgaa caggtggcaa tttctgtgtt atcggcaaat
     4441 atatataggc aatctggtaa aaattatgtt aaaccatata ttataaaaga tgtggagacg
     4501 agtgaaggta atgtaaaagt aggaatattg ggacttacta taaaagaagt aggtaaaggt
     4561 cttaaaaatg taaacttaca agagcaattt caatataagg ataaattgta tgcaaatgat
     4621 ttagtggaag atgcaaagaa atgggtaaaa gttatgaaaa agaaaaaacc agatataata
     4681 gttgcagttg tacattcagg agaagaacca aaaaatccaa aacatccagg aaatagaata
     4741 aaagaactag caactacagt agatggtatt gatgcaattg ttgctagtca tactcatgaa
     4801 aaaatagatg agcatgaata taaaaataag tctggagaaa aagttatagt gacacaacca
     4861 ggtgagcatg gtaaatatta ttctaaaatt acctttaaag taaataaaga aaagggttcg
     4921 tggactatta atgataaatt cagtaaaaca attgaggttg aataacttta taaaatttat
     4981 agataaagta aattatctga tattggcatg atatataaga taaagtttct aatattagta
     5041 taatgcataa tgtgaaatat tttaataata agagaataaa caagacaaat aaaaatattt
     5101 taacatgtaa gatatagtat gaactattat actaatgctt actttataat ttgaacatgt
     5161 tagaataagt cttatttgaa aattttagtg tactagagta agtattattt tactagtaaa
     5221 aaatattgag aactatatgt agatttgctt aaaaaggaat ttacatatag ttcttttcgt
     5281 ataataaata gtacaatctt atatggtaaa gataaagtgt gatattaaat tttattatca
     5341 tccaaaatct aaggaggagt ctcttatgaa aataaaattt attatagtag catcaataat
     5401 atttttaata gtattacttg tggggtgtca aagtactaaa gacacagaaa tcaatgtact
     5461 cgccacaagt gatttacatt caattattcc agataattta atttcctatg tagaagagga
     5521 gagaaaatat gatgagaatc tacttatggt agatgcagga gatttttttg acatgcaaag
     5581 tggtgagatg aataagtggt ttactggtca aaaattagta agatttaaag atgggatacc
     5641 agagtacaaa aaaatagctg aaccacgtga aggagaagtt ccattggcta aaaaaatggc
     5701 aaagctgaag tatgatgcag ttacatttgg gaatcatgaa tttgtatcta atgacaagca
     5761 gagccttgat aaattggttt ctgattttaa aaataacaat ataccattag tatcagcaaa
     5821 cgtatatgaa caatctggag aaaactacgt aaagccatat gtaatgaaaa atataaatac
     5881 tgacaaggga actgtaaagg ttggtatact tggtctgact ataaaagaag taggggaacg
     5941 ttcaaggttt aaaagttttg aacaagataa aaaggctaga gaacttgggg aacaacctca
     6001 atacaaaggg aaattatatg caaatgattt agtagaagat gcaaataagt gggtaaatgt
     6061 tatggaaaaa aaagaaaagc cagatataat agttgccatt gtacattcag gtgaagagcc
     6121 aaaaaatcct aaaaatccag gaaatagaat aaaagaacta gcaacaactg tagagggaat
     6181 agatgctatt gtagcaggtc atacacatga aaaaatagaa cagcatacat ataaaaataa
     6241 ttctggtgaa gaagtaatag taacacagcc tggagctcat ggtaatagta tatcaaagat
     6301 taattttaag ttggataaga agaatgataa gtggtttata aaagacaaat atagtgaatt
     6361 aaaggttttt ggaaaggaag taaatataat tacaacttct ggtctgaatc caaaattttc
     6421 agatgaaatg gcagttaatt tgtttaatga aagagataga gatgttcaac ctatctttat
     6481 agatactgga gattttttaa atactaatac aaaagaaatg actaagtggg ctaaagagtg
     6541 gcaatacaat gaaaataaag gcatctataa aaaaataaat gaatggccaa ttgtatatct
     6601 tggttatgat gctgtagtac ttggtagcca tgaatttaca gaggataaag agacttttga
     6661 ggaaaaaaaa tctacattgg attatattat agaaaacttt gaagaaatga agataccagt
     6721 attatcagct aatatatatg atgaatctgg agaaaattat gtaaaacctt atataattca
     6781 taatgtagaa actagggaag gaaatataaa ggttggagta ttaggtctta ctactactga
     6841 taaggatgaa gaagacttaa gtaactcaag cttaagcaaa gactcaaaga cttcgaaaat
     6901 tcctgaagaa acaggaaagt tatatactaa taatctagta aaagatgcaa gcgaatgggt
     6961 aaaagttatg caaaaggaaa gtcctgatgt gattgttgca gttgtacatt cagataataa
     7021 tagtactcta aaaaatccaa gtagtgaagt caaaaaactt gcaatgtcag tagatggaat
     7081 agatgctatt gttgtaggtc atacgaaaaa taaggtagaa gaacatattt acaaaaataa
     7141 gtctggggat gaggttatag taacacaatc tggagaagat tgttattcaa aaataagtct
     7201 tgaactaaga aaagaaaatg gcaagtggaa tatcataaac aaatatagta aagcaataaa
     7261 aatgaagtga atttattgat atataaacca ttattaacac tgatttttat aatataataa
//
LOCUS       DAMJWC010000121         6835 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMJWC010000121 DAMJWC010000000
VERSION     DAMJWC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6835
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.126"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            74..1816
                     /locus_tag="PC503_003500"
     CDS             74..1816
                     /locus_tag="PC503_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HDF2529450.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            complement(1986..2174)
                     /locus_tag="PC503_003501"
     CDS             complement(1986..2174)
                     /locus_tag="PC503_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529451.1"
                     /translation="MKIITIGSSLITVLLFLSTMICGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYI"
     gene            complement(2171..2752)
                     /locus_tag="PC503_003502"
     CDS             complement(2171..2752)
                     /locus_tag="PC503_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529452.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2920..3738
                     /locus_tag="PC503_003503"
     CDS             2920..3738
                     /locus_tag="PC503_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2529453.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4748..5569
                     /locus_tag="PC503_003504"
     CDS             4748..5569
                     /locus_tag="PC503_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF2529454.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(5879..6658)
                     /locus_tag="PC503_003505"
     CDS             complement(5879..6658)
                     /locus_tag="PC503_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2529455.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         2559 a          910 c          877 g         2489 t
ORIGIN      
        1 tttcttaaca tgcatttttt atatttaata tagtaaaata attaataact atatccatga
       61 ttggaggatt tttatggtta aatccaagaa gaaaatattt gtttttctaa ttttaattgc
      121 agtttttatt atatttgcat catacataag aaattatact aatgatacaa aaaaagattc
      181 tgttagagga actattcctt ttgaaaaaat ggaatataag cgtcctaata tacagtcaat
      241 ttgcgaaaac attaacaagt gcaacgacaa acttttaaca gctaaaacag ctaaggaaca
      301 attaaattta tttaatgaag ttgataaaat ttatcaagat ttttacagta cacttactat
      361 agcaaaaatt agaaataaca tagattcatc agacgaattt tactctaagg aatataagta
      421 tcttatgagt aaatcagtag atgttgacat gtcatacaaa gactttcaag atagatttgt
      481 aacttctaaa ttctctaaag aattagaaaa agaacttgga aaggatacat ttaattatct
      541 aaagaacatt ggaaaactta attctaaaga agttgaaggt ttgcttaaaa aagagcaaga
      601 cctagttgta aaatatgaag acttattagc taaatctaca gtatcaatag atggtataga
      661 ggtagacttt gaagaagcct tgtcaagacc aaatcttagc cctgaagaat atgtgaaaat
      721 ttattcagat tacttaaaaa aatacaatcc tatatttggt aacatattct tagaacttat
      781 acagacaaga actgaaatag caagtaagca aggatttaag aattatatag attatgccta
      841 tatgaaccta aacaaagact attctcaaga agaagctaaa aaatttagac aagatgtaaa
      901 agattacata gttccattat atagagagat ttcatctaaa ccatctgatt cttctattta
      961 tattaaagta tataaaaatc gctcatttag gaagtttgat aaagtacttg aagatatatc
     1021 tccaaaacta aaagagagct tcgactatat gaaaaaatat gacttgtacg attattcttc
     1081 tggaaaaaac aaatcacctg gaggatatac tacttatata aataaatata aagcaccttt
     1141 cttgtttaat acatgggata attctttttt aggtgttact agttttgctc atgagtttgg
     1201 tcatttttat aattactaca acagtattaa cttaaacaat aagatgcaac caagtataga
     1261 tgtatgtgaa gttcattcaa catctttaga aattctattt tataaatatt ttgatgattt
     1321 ttttggtaaa caatctgaag ctataaaaaa agaacactta tcgattgttt taaatactat
     1381 tattgatgct tgtctttatg atgaatttca agaaattata tacaagaatc catatatgag
     1441 tctaaatgat atcaataaat tgttttttga tttagaggaa gaatatggag tttccaataa
     1501 tatacttaga gaaaaaaatg ctcctttttg gatacttgta tctcataact tccaagttcc
     1561 tttttattac ttgagttatg gtcttgcatc tgatgtatca cttcagatat ggcaattatc
     1621 acaagaagat tacagaaaag ctgttgatgt atatatggat tttttaaatc aaaatactga
     1681 tgctggattt aaagatgtgg tagaaaaggt aaatttacaa ttacctttcc aagatggaaa
     1741 tttagaggaa ataagctcta ctttatatga ttattttggt atagataatc cgcttgaact
     1801 aaaaaatgct tcttaatttc taatacttta tactcactct taagatttag tattagattg
     1861 aaataagtga tattttttca cacacaatta atgtttaata aaattatatg gtaaagtatc
     1921 agaaattttt aagactcttg tctttataat ttctgatact ttatttatta ataatattat
     1981 tatttttata tatatataat taaaaggatt gtggaaatca ataaaaatat ccctgtaaaa
     2041 atagcactat tcatatggaa cttaatagaa cttgcatctg ttaccttatt attcttaatc
     2101 cagaacccac aaatcatagt tgaaagaaaa agtaaaacag tgataagact tgaaccaata
     2161 gttataattt tcatcttaca tcaacatcct ctccaataat attttctatt aaaatatcaa
     2221 tgaatttatc tcgctcatat ttattcttta tatttatacc actgtataac tgaaatgatt
     2281 ctgtagataa agcagaaatc tgtattggta aaataatttg cagggcaata attcttagac
     2341 tcatttcatc ttttttattt ccaaaaattt tacgaagcat agggacaata tcaagttctg
     2401 cttgcatatc tccattggtt atacattgat tcaatacaaa aggaagcact ttttcataat
     2461 gtaatccagt atcacacaat ttttttaata aattttttaa atcttcaata ggtcttagag
     2521 tatatacact atcgtcatat agctctgcta ttatatttga catcacatct cctatggcag
     2581 tactcaacaa attatccttt gttttaaaat gataatttat taaaccaact ccaacatttg
     2641 cacgctcagc aatttttcta actgtaatct cctcaatatc atctacttca tttaaaagat
     2701 tcaatgtaac ttcaattata cgttctctag catctttatc attacttttc ataatagacc
     2761 tccaaaacaa ttaacatttt cagttctgaa catgttcagt ataatatttt tttcatcata
     2821 tgtcaatata atttaattat aattttagtt gactctaaca ttatgatatg gtttatatta
     2881 atattaagct aaaagtacct ttataaagga gacaaaaaca tgtttaagat aggcgatttt
     2941 tcaaagctaa gtaaaattag tattcgtatg ttacgtcatt atgatgaaat aggactttta
     3001 actccttctc atacgaataa aactaatgga tatagatact atagtgcaga ccaactttct
     3061 actacaaaca gaatccatgc actaaaagat atgggctttg gcttgtattc tataaaagaa
     3121 attttgacag aatataacga taaagaaagt ctcataaaat atctaaatat ccaccattct
     3181 caagtaaaag aacaattaga agatacacag aaaaaactat taaaaataga aaccactatt
     3241 aaaagaattg gaggaaatga tattatgaaa aattatgatg taactataaa gaattttgca
     3301 ccaaaatata tgatgacact tagaagggtt ataccaactt atcaagacga aggaatgtta
     3361 tggcatcaag catttttaga gacaaaagac cagaatgttc aaattgaacc cccaaagtat
     3421 tctaaagcag ttttttatga tactggatat aaagaagatt atgtagatgt tgaagtacaa
     3481 gttgctgtat ctggaaagta taaagatact gaacatgtta aatttaagac tgttccaagt
     3541 gtgactgctg caactgcaat tgttaatgga aatttcaatc aagttgcaga cgcttgtgag
     3601 gctattggta attggatatc agataataac tatgatgtgg atggtcctat gtttaatatt
     3661 tatcatgtaa gtcctggcaa cgatagtaat cctgataatt gggtaacaga ggtatgcttc
     3721 ccagttaaaa agaagtaatt tttatattaa ttggataata ttttaatttg ttagacaaat
     3781 tacttttagt gttatgtata aatacctaca atttaattag gatattatct taatttgtta
     3841 aacaaattac ttttagtgtt atgtataaat atctacaatt taattaggat attatcttaa
     3901 tttgtcagat aaatcacttg tgatgttatg tttgaatgac tagaatttaa tcaggatatt
     3961 atcttaattt gtcagataaa tcacttgtga tgttatgttt aaatgactag aatttgattg
     4021 ggatattatc ttaatttgtc agataaatca attgtgatgt tgtgtttaaa tgactagaat
     4081 ttgattagga tattatctta atttgtcaga taaattattt ataatgttat gtttaaatac
     4141 ctacaattta attaggatat tatctcaatt tgtcagataa atcaattatg attttatgtt
     4201 taaatgacta gaatttgatt aggatattat cttaatttgt cagataaatc aattataaga
     4261 ttatatacta tccttatact ctagttaaat atattttaat cactaatata aattagtttt
     4321 tttaacaaaa caataaaaga gtaaagtaca aataattcct ttgtactcta ctctttttaa
     4381 ctttctttgt acaataatac aatgataaat ataaaaaatt atatattcca ttctatagaa
     4441 atatgctcac caataacatg tatgttgtta atcaatatat tatatcaaat tatatcaaaa
     4501 ttacataaac cttataggac aatcatatct tattacaaga aaaatgtctt atccatattg
     4561 aataagtcat tcagttcata tacaaagtca atttcattga gaaacattta atatatgttt
     4621 ataaaaattt catactattc tttcatattt acatgtgata taatttatta actcataatt
     4681 ttgttaatca gttgtgcttg tatattattt atataatcta atatttttag aaggtggtgt
     4741 aataactttg aaattaaaaa ttgttggtag tggcggtatg tcaattattc caagttcatt
     4801 ttgtaaatgc aaaatatgtg aagaagccag gcaaaaaggc ggaagatatg aacgattagg
     4861 accaagttta tatattgatg atataaaaat gctgatagac acacctgaag acattgcagt
     4921 agcttgtaac agacaaaaaa tatcggaagt aaaacatatt tcaatttctc accatgaccc
     4981 agaccatgtt aagggtatta gaattgtcga aaaaatagga tgtgacttta tcacaggaga
     5041 aaataatcca attggctttt atgcgcttcc tgaagtaatt gaagatataa accgaacgaa
     5101 tctcgattgt cttaaatatt atggtgatgt tataaattgc atttctatta atgaaacttc
     5161 gcatgtaaag ataaataatt ttgatattga tttgattaac aataacccag acaggaatat
     5221 aaccttctat gttatcaaag agaatgaaaa aaaagtcata tatgcctgct gtaatcccaa
     5281 gccatttact catagtgata tgtactttga tgctgatatt ttaataataa gtctagtttc
     5341 tgatgatggt atattaaatg atggtacaaa acttaaagac acaccattta aagatgaaat
     5401 atttacttta gatgagattg ttgaaattaa aaactattat agaattaaaa aaattattgt
     5461 tacacatatt gacgaaatgt ggggaaaatc atatggttat tacagtgaat tagaaaagaa
     5521 acttgataac atttattttg catatgatgg tatggaaatt atagtctaaa tcattaagta
     5581 ataagcataa tgcaaaataa gaaaacttca atttaacagt atagtcaaac tatgtgatat
     5641 caacatatcg cagtttttac aaaatatcat agtatttatc tttataaaat ttcaagtcct
     5701 acatatttta atacttcaat atctaaataa agtaaaatca aaaatatatt ttatatacat
     5761 tatagacggc ttatcgtcac tagataagcc gttttgtcac aattattatt tgctcaacaa
     5821 aacttctcat aatatataac agattgaatc tccaactgat acttaattac caaaactctt
     5881 attccttaat atgttgttgc attaaccaaa ccttcatcat cattttttgt ggcaatagtt
     5941 ttgctaataa atgactggat tttgtattta taccatacac agaaatatcc ttatttttct
     6001 ttgcatcctt caatgctttt ttggcaacaa cgtctggaga cactatgcct gggaaatttt
     6061 ttgtcccttt ttcagctaca actatacctc tcttaaatag atttgtactc atccaacctg
     6121 gacatacagc aattgcattt atccctttac tcttaagttc aacatttaat gctcttgtat
     6181 aatttcttat aaacgcttta gttgaactat aaatattttg atatggcaat ggctggaatg
     6241 atgcttgtga agaaatattc atgatatggc ttcccttttg catatatgga atacatataa
     6301 gtcccaatgc tacaacagca ctaatattta aatcaatcat attaatagat tcatctatac
     6361 ttaaatcatt gtatgaacag aattttgcaa aaccagcatt gtttataagg tattttatac
     6421 atacattttc tttacttaaa aatgtaccaa tttcttttac ttcttctatt tttgataaat
     6481 cttttgaaaa aatttttacc ttacttccaa attcatctac taattgattt aatctcgcct
     6541 tgtttcttgc aactgcccat atttctgtta tttcttcttc atttattaat aactttagaa
     6601 actctttacc aaaaccacta ttagcacccg ttataattgc aatcttctta taactcataa
     6661 ttattctcct ttaccataag tttatacgct caaactgtaa acttattttt tacaaataaa
     6721 acaccctcta ttcagatgtt atattcatat tatttgagat attatattta tatcattttc
     6781 aataattgtt atatagcata aaaaatagtg ttaatattat agaatcggta ttgat
//
LOCUS       DAMJWC010000122         6557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMJWC010000122 DAMJWC010000000
VERSION     DAMJWC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.127"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            354..1628
                     /locus_tag="PC503_003506"
     CDS             354..1628
                     /locus_tag="PC503_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2529456.1"
                     /translation="MQFMDVSKYIEGANLKVKTKSGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPLLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1835..2152)
                     /gene="trxA"
                     /locus_tag="PC503_003507"
     CDS             complement(1835..2152)
                     /gene="trxA"
                     /locus_tag="PC503_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2529457.1"
                     /translation="MVKIVNNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2419..3171
                     /locus_tag="PC503_003508"
     CDS             2419..3171
                     /locus_tag="PC503_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF2529458.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3158..4039
                     /locus_tag="PC503_003509"
     CDS             3158..4039
                     /locus_tag="PC503_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2529459.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDTSNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNNITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4265..5620)
                     /locus_tag="PC503_003510"
     CDS             complement(4265..5620)
                     /locus_tag="PC503_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2529460.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2521 a          943 c          827 g         2266 t
ORIGIN      
        1 aatcaatttc tttactattt ttacaacttt attagtcata ttcataatta tttctaatta
       61 gtgtttaaca ttttatgtaa aatttataaa aaaatgtata taaattaaaa taagtgacta
      121 tactaaaaat atgatacgga taaacaataa gttcaaccta tctcccccaa aatcaagtga
      181 gctacagttt cccccaactg tagctcattt tcgtgtaatt taataaacat ctcaacaaga
      241 attaattaac aaaacccctt ataaaaacat aacatatatt aaacaagctc ttgattaaaa
      301 cttgagcttt tttaataaaa aacagaatag tttattagat aaggggtttt tttatgcaat
      361 tcatggatgt atctaaatac attgaaggtg caaaccttaa agttaaaact aaaagtggtg
      421 aaactgttaa aagaatatat tttaacaact ctgccactcc attagtttta aaaaacgtag
      481 tggataactt aaactgtgag attcctttgc ttacttatat taatgctcca ggaataatct
      541 cagaaaaaaa tactttaaaa tatgaaaatg tacgctctac tatcctcaaa cttattgatg
      601 gagacgaaga aaaggattct gttatttatg tcaaaaatgc tacagaagga ataaacttct
      661 tagcaaaatt ttttaaagat gaaaatccag ataaatttgt tattaccaca gcaatggagc
      721 atatggctaa ttacctgcct tttaaagtta attttcctac aaaagttgtt ggaattacag
      781 aaaaaggaga acttgattta tgtcaattag agaatatact taaaaattat gctggtaatg
      841 tatctctcgt tacagttaca ggagctagta atgtcacagg tataaccact cctatatatg
      901 aaatagcaag aatagctcat aagtatggtg caaagatatt ggtggatatt gtgcaagtaa
      961 ttcagcataa acctttttca atgatgccac atgaatgtga tgagcatata gattttgttg
     1021 tttttagtgc tcataaatgt tattctccac taaatggagg agctctggta ggacctaaaa
     1081 aattctttga aaaatttaat cctgtactat atggctcagg ttctaccaaa tttgtaaatg
     1141 ataacaaaat actatatgca aacgtacccc aacgttttga agcaggatac ccagagtatt
     1201 ttggaactct tgcaatggga aaagcactga acactttaaa taaaattggt ctaaacagaa
     1261 tttcaaaata cgaaagagaa ttatttttat atgctaaaga agaaatgagt aaaataccta
     1321 atataataat atatggagat aaatcaaata atgtaattat cccaaatata tcttttaata
     1381 taagtaatat gtattacaaa gatgtagcaa aatatttagt tgataacttt ggaatagaaa
     1441 ctggagctgg agtagtaggt gcagatattt atgtacaaaa attattaggt ataagtccaa
     1501 aagaagcata tgtcagattt atgagggaaa atcctgtagg tcttgttagg ataagcttag
     1561 gaatgtacaa tacttttgat gaggtggata gctttataca tgctattaaa actttggctt
     1621 ttaaataagt tttttctatt cttttttatc aataaataga gagtagtttt gttttcacaa
     1681 aaaagcaaat tatatcaaca gtcaatttca ttagcaatta gacactcatt tgtaactata
     1741 caaactattt tacactatac aaacaaaaaa ctcattacaa tgagtttttt tgtttatata
     1801 tgagatttat tttaattact tcaatttact ttaattacat atatgattca attttgtttt
     1861 ttaaattctc cttaggcata aaacctatta atctatctac aggttttcca tccttaaata
     1921 ttagcatagt tggtactgta gatacttcaa atttctgagc taattctata ctttggtcta
     1981 tgtccacctt caagaagttt gctttttcaa ccatctcatt tcctaaagct tcatatattg
     2041 gtgatagcat cttacaaggt ccacaccaag tcgcaaagaa atctacaact actaaaccat
     2101 ctttattttc tacttcattt ataaattcat tattatttac tatttttacc ataatataca
     2161 tctcctttat tatcttcttg atattaatat actacgacct atataacagt tcaattaggc
     2221 acttttttgt aaccgcctat ttttaataga tttaatatta tgataaatag atttataaga
     2281 ttaaatattt ataagactaa atatttctaa tatattttat ttttttctta atatagttga
     2341 cattttttcc cttaaattat aaaatcaaat taataactac ataggtagtt actaatcttt
     2401 tatcaaagga gtttctatat ggataatatt attaatgaat tacaaaatat aggatttact
     2461 aaatacgaat ctcaaatata catatcatta ttaaaggaaa gccctttaac aggatatgaa
     2521 ataagtaaat tatcaggtgt accacaatca aaagtctatg aaaatataac aaagctatta
     2581 aacaataata taattatcaa tgttggaact gaccctatta agtacatacc aataaaccct
     2641 aatgaattat taaaaaataa gaaaaaagaa tttgacaatt ctatggataa tctaaagaat
     2701 agcttacaga tattaaataa aagtaaaagt gtagaatacg tattaaacat aaaaggagat
     2761 aaaaatatat taaaaaaagc aatagaaatg ataaaaaatg caaaacaaga aattataatt
     2821 tcttgccctt atgaagaaat tcttgaatta aaaaaagaac tcctaattgc ttacaaaaaa
     2881 aatattaata ttgaaatact acttttagaa aacaaaagtc tgaaaggtct tgataatatt
     2941 catattcatg gaggtaataa aactacactt gaaaataaaa tgctttacaa aggaattatt
     3001 ttgattgtag ataatgatga aatattgaca ggaaacttat cagaaggcag tgaggccatt
     3061 tcaatttgga caaaaaactc taacatttta tatattggag ttcaatacat aaaacatgaa
     3121 atttatattt cagaacaaat aaaaggaggt tataaaaatg aacaaaatta agattaaaca
     3181 agttgatgct tttacaacta taccttttgg tggaaatcct gctggtgtcg ttactgatac
     3241 ctctaacatt tctgatgaaa ttaagcagaa tgtggctaaa gaaatgaatt tatcagaaac
     3301 tgcatttgtt tcagagtcaa atattgcaga ttttaaagta caatttttca caccaggttt
     3361 agaagttgat ttatgtggtc atgcaacaat aggtactttc catgcacttt tggaagaagg
     3421 gaagcttaat actaataaaa gtatatttta tcaagaaaca aaagctggtg tattatctgt
     3481 agagcttaag aaaataaata atgaaaatat atttatgatg gaacagaata cacctgaatt
     3541 tgaaaattta gataattgca gaaaagaact tgcacaaatg ataggtgtgc atgaagatag
     3601 acttcttgaa tatcctatta taaaggtaaa tactggactt tggtggcttg tatttggtct
     3661 aaaatcttta gatgatttaa aaaatatctc tccagattta aataaaatca aaaaatttag
     3721 tggtgataat aatataattg gtataactcc attttgtata gaaactatag ataaaaagtg
     3781 tgactaccat ttaagatcta tagcaccata tgttggagtt acagaagacc ctgtatgtgg
     3841 aactgggaac gcttgcgtat catcttatat agtacatcac aatattttag ataaaactag
     3901 ttttattggt gagcaaggta actttataaa cagacctgga aaggtatatg taaatataac
     3961 tagagaaaac aataacataa cttctgtaaa aattggagga agtgcttata ctgtcttaag
     4021 tggtgaaatt atgtattaat cccataccta ataaaaacaa ataaaaatac tagctaacta
     4081 aagctagtat ttttatttgt tatttttatt taataatcat actctaacaa atattataat
     4141 tatatatatc ataatattgt atttagaagt aaaattttat ttttattatt aattagttat
     4201 aaatcaatct aatacaacat aattacagta gattaaccta taaaacataa taattgctta
     4261 ctgattattt atcgtcctca acaagtctac ttaatgtctt atcagataag aataataata
     4321 tcgctgcaac aaatagtatt actggaatta tagtatatac tttaatcata tcaaatttaa
     4381 gagtaaatgc atatatatat ccatatcctt taccagctat aaaagtagca aatgtccata
     4441 ctcccataag aacacctaga agcttcttag gtgcatactt acttacaaaa gagttaccaa
     4501 gtggtgagaa taacatttca ccaagactta aaagaatacc aaacatgatt atccatagta
     4561 tactagcttt agcagtttca ggagctccaa ctcctcttga aaattctgca ccaacaagca
     4621 ttaagaatgc aagacctaag aatattaatc caagacctgt ctttttaaat aaactcatat
     4681 ctccttgtgg tctactagca agtttaaacc ataatgctcc aagaactggt cctaatacta
     4741 tacatacaag tgaatttaat gagtcaaacc aagcaagagg aacatcaaat cctccaacat
     4801 tcatgtttac aaatgctgca ccataatcat aaactgcaag ataagttaga taccagaata
     4861 cccagaaaat tacagagaag aatgatataa gtataatagc ccaaattctc ttcttatcca
     4921 tgcttgtaag aggagactta tctttttctt caattttttc agcaactaca ccttctttaa
     4981 aaggtctctt tcctgcattc ccaaggaatc tccatccata tatgaaccat attgcaccta
     5041 ttacacaaag tacagctgct ataaagaaac attgagaaaa tccaagtaca ccattttttg
     5101 caaatgtttt aaggtaaaga ataccaactg ctatagtacc aataaaagaa cctatattaa
     5161 caaaagaata ttgtactgaa aatgctgtat caagttcttc ttgactatca aaaagctgtc
     5221 catttaccgc agatacgtta cctttaaaga atgcagtacc aattgaaact aagattatca
     5281 ttgcatttac catagaaact gtagttgcaa tagaaccaag atagtatcct acccccatga
     5341 taagcatacc tataggtata gtatatctag ctcctatcca tctatctgat atataccccc
     5401 caattatagg tgcaaggtat gtgaatgcaa caaggttggc ttgcattata gcagcttgtc
     5461 ctttatctat tccaagacca ccatgaacta tagctgttgt aaggaatata tatattaagt
     5521 actttgaagc ataatatgct gctctttcaa atgagaaagt tgttgagcag atataaaatc
     5581 ccataggaaa tttacccttc ttttttactg ttgagctcat aattttaaat cctttcttaa
     5641 ttgtattttt attttttacg ttttgtccaa attctttctt ttatgaaaga tataatatta
     5701 ttattttgta aaacaatttg taattattat taagataatt gcgcatttat ttgtagagta
     5761 catattctca tggaataaaa ttaatacact tcttaatcat aaatttaaat tatataaatt
     5821 cactattttc agatatagtt ataaattaat atattctcat ctaataccat gaaaaaacct
     5881 tcgccatatg caattcttat tttttacgtg atagtatttt acaaactaaa atcccccttt
     5941 tgtagcaact tatgtaatta cattttagtg cttttttaaa ggagtctcga ataaagcaac
     6001 atatattttg ttcaaataat gtttttattt attttttaaa tttatatatt acttcaccca
     6061 accaattctc aacttaaata actaaactac tatctattca cagattaggc ttatttctta
     6121 cacattagtt tataataaac actgtgaatc taaacataaa aactgttatt ttaaagtaat
     6181 tacccatata ttcgctttga tactatttat tgaggctata ctctttatgt ataatatatt
     6241 atttataaaa tacctcaaaa tatattattc ataaaatacc tcaaactgaa aactttttca
     6301 cgaatattta tttttcacct cccctttttt atttcaccat gtaaatcgta ccataaatat
     6361 gcacttatat gcaagaaaaa aatctattaa tcgacagtaa ataattagaa aaattcaaat
     6421 tatatttatc aattatatta tataaaatat ttcctatgaa aatataaatt aaattaatgt
     6481 tcagaatagt ttttagatat gaaatcttga tttttttatt actttactta tttgctcaaa
     6541 tatatttttg tatgcag
//
LOCUS       DAMJWC010000123         6373 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMJWC010000123 DAMJWC010000000
VERSION     DAMJWC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.128"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(335..742)
                     /locus_tag="PC503_003511"
     CDS             complement(335..742)
                     /locus_tag="PC503_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529461.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1216..2100)
                     /locus_tag="PC503_003512"
     CDS             complement(1216..2100)
                     /locus_tag="PC503_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2529462.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2391..2867)
                     /locus_tag="PC503_003513"
     CDS             complement(2391..2867)
                     /locus_tag="PC503_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF2529463.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3133..4308
                     /locus_tag="PC503_003514"
     CDS             3133..4308
                     /locus_tag="PC503_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF2529464.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4389..5192)
                     /gene="proC"
                     /locus_tag="PC503_003515"
     CDS             complement(4389..5192)
                     /gene="proC"
                     /locus_tag="PC503_003515"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2529465.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5232..5816)
                     /locus_tag="PC503_003516"
     CDS             complement(5232..5816)
                     /locus_tag="PC503_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529466.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2103 a         1083 c          719 g         2468 t
ORIGIN      
        1 gttaaggtct acccacttcc actaccaata gcttgtagtg tacttccctc aagaggaata
       61 gtcgttgaag tttctcctat tcggagttta cctgctgatt gcccatttta aagtacttag
      121 gatttaacct tataccatct aaccaatttt ttctactttc gtaactttca cacttaggtt
      181 tatttcatcc ttatgtttta gtttgattag ctttaggggt ttccagcaat tcaagtagta
      241 ttggataggt tctatcctat ctctacatat aggtttccct atatgctgac tattttagct
      301 actaactcat gactaaagtc acgagtgtgc gtagctattt tttaatcaat attttagtaa
      361 attttacggt aagtaaaaac ctctctcctt caaatcctat agcaaatata cttacaagtt
      421 gctttgagaa aataactcct aatatagcta caactatgca tataccaact attatattta
      481 aaacattgtt taaaaacttt agtgcttgct tttcaccttg tttactactt atatcttgat
      541 acattggaat aaaagtagta actatagcag tacctattgc tgcaaatata atatttggta
      601 tattcatagc tgttaaataa ctctctgtat ataagcctgt accataaatt gatgataata
      661 ctaattctct acccattcca agaatcttag agattatagt aactatcatc aaataaaaag
      721 ttgctttagc taccttgctc attttatcac tccacttcta acatacctct ttttaatcaa
      781 gtaaaattta gctcattaga tataattcta tcaactaatt tgccttgctt agccctatca
      841 aaatataatt aacacctatt tcttaatata tcacaaacta cattattctt catatttttt
      901 tatttctcca ataagtttta catttttcct atataaattg tatagcttca attatattca
      961 aagaaatgga gttgctaccc gataacttta aaagtaaaaa acagatttta ttatcttttt
     1021 aaactatatt ctaacatatt ttgtccatat tgagaaattt tactaaacta ttatgtactt
     1081 tattaaataa ataaaataac agcacaccta taaaatacaa gtgtgctgtt cataaacaga
     1141 ttttataaaa aaataattcc taagtagaga ttaacatgct ttctcatact ctcatatata
     1201 atgtgtctaa aaatattaat aaaaatgctt taattgtttt aacttacttg gatgtcttaa
     1261 ttttcttatt gctttagctt ctatctgtct tattcgttct ctggtaactc caaatacctt
     1321 tccaatctgt tctagtgttt tagggtcatc atcatcaatt ccaaatctca ttcttaaaac
     1381 ttgctgttct tgctctccaa gacctgtaag tagttcttct atcttttctt ttaaattatg
     1441 ctgttcaact tcgtgtatta caacatcttt aaaatcagca tctgatggta taaattcaac
     1501 taaactacta tcctcatctt cttttaatgg agtatccaaa gatacaacat ttttatctct
     1561 tcttaataat tccaacactt tgtcaacttc taagccacat gcatctgcaa tctcatctat
     1621 agttggctct cttaataata catttaaaag ttcttgtttc tttttcttta caaaatttat
     1681 tctctgatga agatgtatag gtatcctaat agtattttcg caatcgtcga tatatcttgt
     1741 tatactttgt tttatccacc aagttgcata agtgctaaat ttgtatcctt ttttataatc
     1801 gtacttttct acagctttta taagtcctat atttcctgct tgaattaaat ccaacatatc
     1861 aatactatct cttttatatc tctttgctat gctcactacc aacctataat ttgaatttat
     1921 aaatttttct tttgctactg aagatgagtt gattatttcc ttagccagct ctacctcttc
     1981 tcctgctgac aacattttgt attcctctat ttcctttaaa tacattttca tcgcattcga
     2041 tacatttgat gaacccacac aaatataatt ttcataatta ttttcttttt tagtatccat
     2101 aatcaaaccc cttctattca tagaatttgc taaaacaaaa ataaataatt taaacctaca
     2161 taatctacaa ttacataata tcccattctt taaatgaatt gttttgtata ttatgtatac
     2221 aaatttataa aaactatacc tataatatta ttctacttct aacagcaata tcctccttat
     2281 atatataatt tattttatta tatgttgtta tattcttagt tttttgaatg atatatgtct
     2341 aaaaaaagac tgtttactaa acagtctttt tttatatata tgctcaatat ttaattttca
     2401 tgatgatgat tacatccaca tccacaattt tcatcatggt gatgatgttc ttctaaatct
     2461 tttacctgtt gttccatttc atgaaactct tttaccatta tatcataagt tggaagagct
     2521 gcctcagtat cgtattcttc ccctctccaa tcagcgtaca tcatagcatc tccattagtt
     2581 aaaaccaatc tacctgacat agttatatta tccacttctt ctaaaaattc tatttgtttt
     2641 tgtaaaactt ctccttctaa ctccacatct tcatctaaac attgcactat cattacaggt
     2701 gcataataat cttcttcatc tttaacattt acaacaatat ctaaaattcc ttctgcacct
     2761 tcttcaaatt ctgccaactc aacatttgta tcaatcatat cttgaggtac taataaatct
     2821 tctattaaat attttattac tctatctttt actaattctt ttgacattta tttttctcct
     2881 tccgattcta taacattatc ataatcattt ctatattata gtatactaca ttaattgttt
     2941 tttcaatctc ttacaaaaat tattttttat tatcttcctt atattccctt ttttattaca
     3001 aagttgtaat cgcattgatt taaaaaatag tttatattta gtataataga aatgtagcac
     3061 atatttttat tcaatatatt aataaaaaaa tatattgaaa atgtaatgta tgttaaatct
     3121 aggaggaata ttatgaagtt taaaaaacaa attagttcta ttgttgtgtc tactatgctt
     3181 gtacttggga gtatgaacct ttcttatgca gacggtacaa atgtagttac acttggagct
     3241 aacttatcag agtctcaaaa gcagcaaatg cttaattact ttggagtaaa aaaagaccaa
     3301 gtcttagttt tagatgtaac aaatgcagaa gaaagacagt atttacaagg tgttgcaaca
     3361 gagggtcaac ttggaaaagt tactatctct tgctcatacg ttgaacctac taaaaaagga
     3421 aatggaatta atgttaaaac agcaaactta acttgggtaa ctagttcaat gattgcttca
     3481 acccttacaa cagctggtct tgaagatgca aatgttattg ctgctgctcc atatcctgta
     3541 agtggtactg gagcattgac aggaatcatg aaagcatttg aggatgcttc aggaaagaaa
     3601 cttgatgaaa ctaagaaaga aattgcttct gaagaattgg tagttacagg tgacttagga
     3661 gatgatatag ggcaagaaaa agcaacaggt gtaatgaatg atataaaaac agaaattgta
     3721 aagaatggta caaaagatac caatcaaata gcaaatacaa taaataatgt tgtaaataat
     3781 tacaatatta ctattacacc agaacaaaaa gaacaaatta aaggtgtaat gaaaaaaata
     3841 gctgaccaaa attacgatta caatagcatg aaaaatacac tagataatgt atcagataat
     3901 gtaaatgaac aattaaagaa attaggtgaa agtgttaagg gttctggtat actagatact
     3961 attggtggat ggtttagtgg aataggagac tggttctctg gtttattctc aggcggagat
     4021 aaaaaagatt tgggaatctt aaataatact aatgatgagt ctcttggctc tgatgctgta
     4081 ataaattcta cagaaggtgt tcaaataaat ccacaaaata atactaattc taacaatgat
     4141 agtgatacaa atagctcaaa aaatgatact tcaagtaata atgaaaataa cgatagttct
     4201 caaacaaatg aaaacaacac aacaaataat tcagaaaatc aatcaaataa taatgactca
     4261 gttggtttct ttgaaaaaat aaaaaattgg ctttcaggct tattttagaa attaaacaaa
     4321 taaaaagaat tgcctaaaat ggaaattttc tataaaaggc aattctcttt atttacaata
     4381 aatttttatt actcactcat ttttttagat ttttctatac atgcacatat tgcttttatc
     4441 acagaagctc taaaaccttc ttcttcaagt actttaactg cttctatagt agttccacca
     4501 ggtgaacata ccatatcttt taattcacca ggatgttttc ctgtctcaag taccattttt
     4561 gcagaaccca taacagcctg tgatgcaaac ttatatgctt gtggtcttgg cattcctgca
     4621 attactgctg catctgctat agcttctata aataaaaata catatgctgg tgcagaacca
     4681 cttgcaccaa ttacagcttc tataagatac tctggtacta cctcagtatt tccaaaagaa
     4741 ttaaatactt ctgtaactgc ttctaagtct tctttgttta tatttttatt tatcgaaaga
     4801 gaagacatgg cttcatttac aagagctgga gtatttggca tagttctaac tattttttta
     4861 tcttctccta taatagactc tatatctttt atagattttc ctgctgctat tgtaactata
     4921 attttattgt catctataaa gtcttttatc tcttccaaaa tatcatcata tatatctggt
     4981 ttaacagcta caattactat atcagaggtt ctagttactt ccttcgagtc ttttgtagta
     5041 tttattccaa aatttgcatc tattctatcg agagttcctt gactatatgc tgatgctata
     5101 accatattag gttcaactaa ttttgaattt actattcccc ctatcatagc gcttgccata
     5161 tttcctgcac ctatgaatcc aatttttttc actttagtac ctccttattg actaatagta
     5221 atcgttaaaa tttaagcttc tttaactgca tcagattttt caaatggatt tggtatactt
     5281 actaccaaaa ttttcactac cttattagta tagttgaccc aattatgatt gttcttttca
     5341 ctattatagt gtattgtgtc tcctggatac atttctattt gttcatctcc caaaaacact
     5401 gtaagagtac cctctaatac atacacaaat tcctcacctt catgtacgta acaacaaatt
     5461 tcctcactac tcttacttgg aagaatttca attaatcttg gtagcattgt tttttccttt
     5521 aaactagatg ataaatgata atgtataaat gttgagtttt ctacatcaaa tacttctttt
     5581 tcataacttc ttaatacagc tcttttatgc tcttttggct tcataaaaaa gtaagttaat
     5641 tctacatcta gtacacttgc tatttttcct aaggaatctg ttgccacact tgttaatcct
     5701 ctttcaagtt gtgataaaaa accaattgac aagtttgttt tttcactcat atccttcagc
     5761 gtcatttgct tttgagttct gagttgcttt atttttgctc ctatgtcctt attcaaaacc
     5821 atcaccccta aataatttta attttttcat aatataaata caaaaatata aatataggta
     5881 ctgaacccat ctttatttca tttaaaaaaa tttttataag tattactata atttatcaat
     5941 ctttttttgt ctacattttt acgattattt acgatttatt tttcacatat gtatatttaa
     6001 tcttgccaac taaagataca ttttttataa gcatttactc tttatataat aaaacttaag
     6061 ttgttcatgt agtcttcttc tggtttaatt attaaaattt caaattatat tattatttct
     6121 acacattatt acatccttta gtacaattat aacataattt tacaatttaa tgatatctat
     6181 tcaatgtctt tttttactct acaacatatt ttattttaga gtttaatact atatatattt
     6241 tttatataca gccttgtcat tttttagatt gtcaagagtt attgaagtat tttatgtaga
     6301 tttagatttt atttcctaat ttctcattta acaagaattg cttatgataa aaaataatat
     6361 catctcaata aga
//
LOCUS       DAMJWC010000124         6360 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMJWC010000124 DAMJWC010000000
VERSION     DAMJWC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.129"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            242..952
                     /locus_tag="PC503_003517"
     CDS             242..952
                     /locus_tag="PC503_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529467.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
     gene            1475..2812
                     /locus_tag="PC503_003518"
     CDS             1475..2812
                     /locus_tag="PC503_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2529468.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPINILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(3148..3717)
                     /locus_tag="PC503_003519"
     CDS             complement(3148..3717)
                     /locus_tag="PC503_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2529469.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVEGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            4087..4692
                     /locus_tag="PC503_003520"
     CDS             4087..4692
                     /locus_tag="PC503_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HDF2529470.1"
                     /translation="MTNWNLWRTLNMEYIINPCSGIKIKITRGQKIEIVDIEGGQVVD
                     FFAEMKDDSTEFISPGVTIDCNESLRLQVGNLIYSNKYRPMFKILYDDVREHDLLHPC
                     CRPEMYDFFYHNGENHPNCFDNINRTLGTSHQIIHPINLFMYTKVNTDGSIEVCEPLS
                     KANDKIILEALENMTLGIAACSVSESSCNSRKCTSIKILVD"
     gene            complement(5371..6273)
                     /locus_tag="PC503_003521"
     CDS             complement(5371..6273)
                     /locus_tag="PC503_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2529471.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHKYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
BASE COUNT         2329 a          975 c          753 g         2303 t
ORIGIN      
        1 ctttttataa taataaaagc atttgtattt tataataaga aagattgtta gattttttaa
       61 taagaaaatc attagcactt cagaataagt ttaatagaat agttttaagt gtaagtatac
      121 taatataaaa aattttattt tgctatctgg atataattgt tatttcattt tatatatcta
      181 ggtagcaaaa tatattatat acttaactat ataaatataa aacttgaaag gagataaaaa
      241 attgacttcg atttgtattt gtgatgatga aaaacaacaa agaaacatgc tgaataaaat
      301 cattacaaga gaaatggatt tgtggggcta cccctaccaa ataaaagaat attcaaatgg
      361 agaaagtcta gtatacaatc tagaacacga aaattattac atagatatta tttttttaga
      421 tattgaactt ggaaaaagta atggcgttga catagcaaaa actatacgaa aacattcaaa
      481 agatactata atcatctttg tcacaggttt ttctgactat gtatttcatg gatatgatgt
      541 aggagctttg aactacatct taaaacctta taaaactgaa aaaatatgta aagtattaaa
      601 agaagcacta aaaaaattag aacaatggaa agaaaacttt attacagttc agattggaac
      661 taatctttgt aaaattaata caaaagatat cctctacttt aaaagtgagc taagaaaatt
      721 aactgtagtt acctttgata aaacattaga atactacgga aaattaaatg atatggaaac
      781 tgttcttccc tctaatttta tacgtacgca tcaaaggtat attgtcaatc taaaccatgt
      841 agatagtata actcaaactt atgccaaagt tcagaatgaa aaaattccta taagccgtaa
      901 aaaatatcaa gaggttgtag gaaaatttac aaggtatatg ttagaatctt aatttttgaa
      961 gttcaatctc tagaatttta tttttgaaac ttaacttttt aaagcttagt ttttagagtt
     1021 ttgttttttc aaatttaatt ttttgaagct taatttctag aatttcaatc tttcaaaatt
     1081 taattttttg aagcttagtt tttagagttt ttttcaaact taatttttta aagctcagtt
     1141 tctagaattt caatctttca aaatttaatt ttttgaagct tagtttttag agttttttca
     1201 aacttaattt tttaaagctc agtttctaga atttcaatct ttcaaaattc aattttttga
     1261 agcttagttt ttagagtttt tttcaaattt aattttttga aacttaattt ttaaaatttc
     1321 aatcttttaa aactcaattt tttgaagctt aatttctaga attttatttt tcaaaatcaa
     1381 ttctttgaaa tctaatttcc agaattttaa tttttaagat ttaatttttt aaaacttagt
     1441 ttccagaatc ttaattaata gaaaggtata ttaaatgggc acttattctt taatctctac
     1501 aagcataaat tttattctaa tattaatcaa tattttcata gccttttttc tttataagtt
     1561 gacttcctat tttatagact ttaggaatca ttggattttc aaaatcatat tgattttggg
     1621 ctactctatt attagtcaaa tgataatatg gctttccgac cccataaata ttttgtttac
     1681 actattcgga tattttatac tacttataat atgtagcaaa agcaaattaa ttcctataat
     1741 atcagttgtc atgatacttt atcctattat aattgggctt aattttcttt ttataaacaa
     1801 ccctatatat gaggaactta tacactcaaa agagtatatt ttaatacttt caatagtcca
     1861 gataatttct gctctaatta aattattatt ttggttttta atacatattt tcctaaagaa
     1921 tagattggtc aatataaaac aatacttatc aaataaaata tggattttta ttgatatggt
     1981 atgtatatct tcatttttat caatattaat tgctattatt ctgccaccta ctaatttaat
     2041 ccctatgggt agtaataaga atattatctt aggcaactta ccttatggca cttatctaat
     2101 catcttgtca gcaattctgg caaatatcgg tgtgatactt cttttacagc cattgattga
     2161 aaatgtaaag atgaagatag aaaaacaagc aaatcaccta aaagaaaaat actataactt
     2221 actagaaaat caacaaattc aaatacgcaa aatgcgacat gatatgaata atcactttca
     2281 aatgattgaa tcgtatttag aaattgaaga tattgctgga gctaaaaagt attttaatca
     2341 gttaaaaata ggtataggta ctcttagtgg aaaacaattt tgcaaaaacc aagctcttaa
     2401 ctcaatttta aatcttcgtc atacaagttt agaagaaaat ggtgttgatg tgcactttaa
     2461 tatagatata gacaatcact tgggtataga acctatagat ttatgtacta ttttttcaaa
     2521 ttctttagat aacgctatag aagcatcttt gaaaattcct gatttgtcaa atagaaaagt
     2581 ggtattaaag gcacgttgtg agaaggagta ttttagctat ttattgacaa acaacaaggt
     2641 aaatcctatc aatagaaaac aagaactatt tatttcagat aaaaaagata gtaattctca
     2701 cggatatggt attgagaata ttagagaaat tgttaataag tacaatggaa aattggatat
     2761 ttcttatact gagagtgaat tttctttatt tctttatatt agattatttt agtctaaaat
     2821 tagattatct tatataatac aaattagatt gtttgatact atgtaaaatt ataataactt
     2881 ataattaaat atttacacat atattcatta acttaaaatt taatcaaatg tgatatttta
     2941 tttaccttag taaaaatgtg tgtgtctcaa aataaacttt ttagttgatg aggcactctt
     3001 ttttacatga aatcaaatat atttttatcc tttcaacaat gaaaaatgga tttatctctc
     3061 cattttgaaa caagcccttt ttctattaat tactttctta aaaaatataa tacgatatat
     3121 aagataaata tctaattgta cctatttcta attatatcta ttagaataca acacctttgc
     3181 cttttcagta aactccctaa caaaatctag tttactatct gtataagcat cacgattatg
     3241 ctcatacttc ttccaaaggt ccaacttaag tttttcatac tcctttgcaa catctgggtg
     3301 gtcaattaag taatctctaa aaaacaactc atcattatca cctacatacc ttatatgcaa
     3361 atgaaaaact cgttcttcaa acccctctac tgtataccct ttattaagtg aaagcctact
     3421 actgctctca gacatacaaa tatatccatt cgactcaatc aaatctttaa tatctttcat
     3481 attataatca ggaattatct caatcagtat gtcaacaatg ggcttggcat aaatcgtact
     3541 cacagaagta cttccaatat gacttattct aacaattttt tgcattggca atattccagt
     3601 tagtctatat tgttcttctt taaaccaatt tttccaacat tctttgtgag tagtcaaaaa
     3661 tataggaaac aagttccata actcctctaa agtcatatct tccaacttct ttttcattag
     3721 ttacctcctt ttaaatttgt actttatatt ttttcttttt caaatttact tagttaatat
     3781 ttaactttat tttttatcaa atcatttttc taattatgta aatttttcta aatttagttt
     3841 ttaatgtatt ataacagatt tttacccttc ttacactttt gtatctattt aaatattaga
     3901 acattttttc ttacttctaa atacagtaag attgcttaaa taccaaatag gagcaaaaaa
     3961 actctgtaat ctaaaaaaaa ctacaacatc tttatgagaa ttaaaaaatg atagactatg
     4021 ttatcaacat taagaaacag atagaaaaga aacagagtat gtgctaaaat gggaacatag
     4081 aacagaatga caaattggaa tttatggagg acattaaata tggagtatat aatcaatcct
     4141 tgtagtggta taaaaattaa aataactaga gggcagaaaa ttgaaattgt ggatattgaa
     4201 ggaggacagg tcgttgattt ttttgcagaa atgaaagatg attcaactga atttatatct
     4261 ccaggtgtta caattgattg taatgagtca ttaagattac aagttgggaa tttaatatat
     4321 tctaataagt atagacctat gtttaaaatt ttatatgatg atgtaaggga acatgacttg
     4381 ctacatccat gttgtagacc tgagatgtac gatttctttt atcacaatgg agaaaatcat
     4441 ccaaactgtt ttgataatat taatcgcaca cttggaactt cccatcaaat tattcacccc
     4501 attaatttgt ttatgtacac aaaagtcaat acagatggga gtattgaagt atgtgaacct
     4561 ttatcaaaag ccaatgacaa aattattctt gaagcattgg aaaacatgac tttagggatt
     4621 gctgcatgca gtgtttcaga aagttcttgt aatagcagaa aatgtacttc tattaagatt
     4681 ttggttgatt gacaaatttc atttatcgaa aaaatatcaa aattaaaaaa tgacgtcaaa
     4741 ggcgcaaaag ggtaaccact tgcgctctca attcattatg gtttgttacg tatttatggg
     4801 taaaaatccc ttgattctat gatgtttttc agacacaatt acaaatgagt aaggatttta
     4861 tactcatact ctaaaaaata gcattttatt gcgtaacaga acgaaaaaac agtgtgtacc
     4921 tttttcttgc aatacacact gtattcatag ccactctagc tgttaactgt taattatctc
     4981 ataataccct tactggtatt catctaatct taaccccttt taattatttt catttataaa
     5041 taaattctat tcttcccaaa atatcgtaat taaaatatat taattaaaat atcccaataa
     5101 gaatatctga aaaatcttct acctattttt tcaaaccttt tattcccatt cctcatacaa
     5161 tagtgcaact tttagcacag tataaatata ccattagtcc atataatctc attaacaaat
     5221 atatacaatt attttcttca aactctttta tatctaagat atcacatttt cattttctta
     5281 tattaattcc ttaactctct ttcaaattac caatttttta atcaaatctt cattaaatat
     5341 tctatcatta ttaaacattc atcattatcc ctaaaaaata tgtgccgtat gttctttaca
     5401 caaattttcc atcttatcat acacagcacc actatctctc tcatctgtca tagtcacaat
     5461 tacatcactt ggtctaagaa ttgtcttacc tctaggaata atttcttctc cacctctttg
     5521 aattgctacc aaaagacaat tttcaggcca ctgtacatcc tgaattgcct tgttcgcaac
     5581 aggagagcca aacataacag agaactggtc tagtatcttt tcgcccctct ctttatgtac
     5641 aggttctcca ttcttttcaa gtaacctctc aagaagactt tcataaatag gtttagactt
     5701 cataagtgta gccacaatat atgccacaat tgaaattact gatagtgaaa gcatttgact
     5761 aacagaacct gtcatttcaa aaattaatat gataccagtc aaaggggcac gcacaatagc
     5821 tgtaaaatat cctgccatag ccaaaagcac aaagttattt acataatcgg gattcattcc
     5881 aaaaacttta acacctacca taccaaatat tccacctata aatgctccta aaacaagcaa
     5941 tggaaaaaat attccccctg gtgcacctga cccaaaacta acagccgaaa atataaaacg
     6001 tataacaaaa atcaaaacaa ccattccaaa aatatattta tgacttgtaa gttcttcaac
     6061 taaattgtgt ccactcccca gaacatcagg cataacaagc ccaagaatac cagccattat
     6121 aaatggaatc aacagttttc caaacgtacc aattttagga atcttcttgt ataaagactg
     6181 cacatataga gtaaaccagt tgtaaaatgc ccccataact ccaagaataa cacctaaaat
     6241 cactattaat ccataataat cttgtggcaa cacatttcca atctgaacct cccatgacta
     6301 aagtcacagg gttcctgctt catagaattt tgcatactaa aatatgtctt actaattctc
//
LOCUS       DAMJWC010000125         6351 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMJWC010000125 DAMJWC010000000
VERSION     DAMJWC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.130"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            285..1229
                     /locus_tag="PC503_003522"
     CDS             285..1229
                     /locus_tag="PC503_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF2529472.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1251..1877
                     /locus_tag="PC503_003523"
     CDS             1251..1877
                     /locus_tag="PC503_003523"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF2529473.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1911..2960
                     /gene="hisC"
                     /locus_tag="PC503_003524"
     CDS             1911..2960
                     /gene="hisC"
                     /locus_tag="PC503_003524"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2529474.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2963..3541
                     /gene="hisB"
                     /locus_tag="PC503_003525"
     CDS             2963..3541
                     /gene="hisB"
                     /locus_tag="PC503_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF2529475.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3543..4148
                     /gene="hisH"
                     /locus_tag="PC503_003526"
     CDS             3543..4148
                     /gene="hisH"
                     /locus_tag="PC503_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF2529476.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4145..4867
                     /gene="hisA"
                     /locus_tag="PC503_003527"
     CDS             4145..4867
                     /gene="hisA"
                     /locus_tag="PC503_003527"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF2529477.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4849..5607
                     /gene="hisF"
                     /locus_tag="PC503_003528"
     CDS             4849..5607
                     /gene="hisF"
                     /locus_tag="PC503_003528"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF2529478.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5635..6303
                     /locus_tag="PC503_003529"
     CDS             5635..6303
                     /locus_tag="PC503_003529"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF2529479.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDVIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2598 a          537 c         1256 g         1960 t
ORIGIN      
        1 agaatattaa taaaaattat ttgggaggaa attatcatgg tgagattaaa tatagtaaaa
       61 ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta atatgaaatt
      121 aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg atgggaagta
      181 attttaagag aaaattatag ccatataggt ataaagccta tgtggctttt ttattgtttt
      241 aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa tttttgagga
      301 ttgaagatga ggttatttat tctaaaaaaa gatataaatt aaaaagggaa atagataaac
      361 tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa tatgatgaat
      421 ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta aatggaaaag
      481 taatggtact tagagctgat ataactacaa gtataataaa aagccttgta ccaagatggg
      541 aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat aaaaatacag
      601 ttggaataaa agagataaga caaataggtt gtgagtatct aggagaagcc tctgtagaag
      661 cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat aataatttta
      721 ttctagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta aatttaaata
      781 agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat gaactaaaag
      841 tatatattga agaattaaaa attaagcgtg aagtaaaaga gttattatca aatattttaa
      901 gtttacaagg gaatttatat aatgttattg aaaaatcaaa caagttctat tgtaataata
      961 agatgaagca agctcttgaa gaattaaagc aagtaaataa tttaattgag gaatgtaatt
     1021 ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat tatgaaggaa
     1081 ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggc ggaagatatg
     1141 attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca ctaagtgttg
     1201 atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct ttggattatt
     1261 tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa tttaaaaaaa
     1321 tgggtctagg agacagtata gacacagata cgagaaaact aatttttaaa gatgaagaaa
     1381 ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt gaaaaaggag
     1441 tcgctgacct cggtatagca ggtaaagata ctattttaga aaatgagaca gatgtatatg
     1501 aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta aagggagata
     1561 gcatatatag agaagatgaa tatttaaaag tggcaacaaa gtatcccaat atagcaaaaa
     1621 agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt tctgtagaac
     1681 tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact ggcaatacac
     1741 ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct agaattatat
     1801 caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt cgtttatttg
     1861 aagaacttga taattaaaat ataattgagc tttataagga gggatttaag ttgagagaaa
     1921 aagaaagcat aagagagtta aggggatatg aaccaaatca cgtaaactgt aaagtaaaac
     1981 ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa atttcagata
     2041 gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa gaatctataa
     2101 tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga aacggttcaa
     2161 gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta atattgagtt
     2221 tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct aaatttatag
     2281 gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa aaagtaaagg
     2341 agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga acaatattaa
     2401 agagggaaga gataataaag cttttagatt caactaatag tctagtggtt ttagatgaag
     2461 catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat gataatctaa
     2521 tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca ggatatatgt
     2581 tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat aatttaaatt
     2641 cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta aaggcttata
     2701 taaaggaagt aaaagaggaa agagaagttt tatatgaaga aatgattggt atgggaatta
     2761 aagcatacaa atcacaagca aattttatat tattttattc tgaaatcgaa aatttatcac
     2821 aaaaacttat tgatagaggt gttttaataa gaaaatttgg tggaaagtta gaaaattatt
     2881 acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct ataagagata
     2941 ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata ctcttgaaac
     3001 acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag atactggaat
     3061 aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg atttaaaagt
     3121 gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata taggtatagc
     3181 tataggtgaa gcatttaaaa atgcactagg tgacaaaaaa ggaatacgaa gatattctaa
     3241 tatctatata cctatggatg aatctctatc aatggtagca atagatataa gcaatagacc
     3301 ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga gtactcaatg
     3361 ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac atatcaatct
     3421 cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat ttgcaagagc
     3481 tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg gggttttgta
     3541 gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct aggggtttta
     3601 gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa caggcagatt
     3661 cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta gataaactag
     3721 gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata ggtatatgtc
     3781 taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa ggattaggac
     3841 ttataaaagg aagtattgat aaactggata taagtttaaa agtgccacat atgggatgga
     3901 ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaat gaagatgatt
     3961 atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta attgcatttt
     4021 cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat ggtatacaat
     4081 ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat ggggagatga
     4141 taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa gactcacaca
     4201 aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag catataaatg
     4261 gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta gaagtgaatt
     4321 tggtgtaaat acaaaaataa ttgaggacat agcaaacaat atagatatac ctattcaagt
     4381 tggcggtgga gttagggata aggaaaaagt caaaagttta ataaatgctg gtgttactag
     4441 agtaatatta ggtagtatag cgattgaaaa tttgaattta gttgaagaat tggtcaatga
     4501 atataaagag aaaattgtag tttctataga tgctaaagat ggaaaagtag cagttagggg
     4561 atgggaagtt gtaagcaatg tagactcatt aacattatgt aaacaacttg aaaagatagg
     4621 tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag gtccaaattt
     4681 tgacatatat gaaagaatag caaaggaaac atcactaaat gttattgctt ctggaggcgt
     4741 aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg caataatagg
     4801 taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat gcttactagg
     4861 agaataatac cttgtctaga tgtgagaaat ggaagagttg taaaggggaa aaaatttaaa
     4921 gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga ttgtggtgca
     4981 gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac atctttagaa
     5041 tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg aggagtaaat
     5101 aaattagaag atttcactga tattttaaga aaaggtgctg ataaagtttc tataaattca
     5161 tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg agcacaatgt
     5221 gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt atacgtaaaa
     5281 ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg tgtagaactt
     5341 ggagcaggag aaatcgttgt aaatagtatg gatgaagatg gaatgaaaaa tggatatgat
     5401 atagaattat tatcaaagat aacttcttta gtaaatgtac ctgttatagc atctggaggc
     5461 gctggaaaaa aggaagattt ttatgaggcg gttaataaat ccaatgtaga tggaatttta
     5521 gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa atatttaaaa
     5581 gacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag aaatatggat
     5641 aataagtgta acaatgtata cagtgatgaa gtagagaaat ttataagaag tataaagttt
     5701 gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagcaaaga tgtactgatg
     5761 ttagcatata tgaataaaga tgtgataaag aaaaccttaa aagataaagt agcttgctat
     5821 tttagtagaa gtagacaaga actttgggtt aaaggtgaga catctggtaa tactcaaaaa
     5881 gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt tgaacaaact
     5941 ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt tgatgatagt
     6001 tcaaaaatgg agcttgaagt acaaacaaat atattgaaag aattatatga tttaatcaat
     6061 gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga aaaaggaata
     6121 gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc atcaaaaaat
     6181 actgataaaa gtgaacttat ttacgaaatt agcgatttag tatatcatac attggtttta
     6241 atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa aagaagaaaa
     6301 tagaataaga tagattaatg ggtaataaga aaatatacca cttttaataa a
//
LOCUS       DAMJWC010000126         6032 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMJWC010000126 DAMJWC010000000
VERSION     DAMJWC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6032
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.131"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..410
                     /locus_tag="PC503_003530"
     CDS             <1..410
                     /locus_tag="PC503_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4004 family protein"
                     /protein_id="HDF2529480.1"
                     /translation="IANMFMKKDINKEFDIDFILSKEVICNYTKEIFQNLYKKEQSIG
                     KKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKIYLFRKFGVPFVVG
                     CLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(710..1297)
                     /locus_tag="PC503_003531"
     CDS             complement(710..1297)
                     /locus_tag="PC503_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2529481.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(1383..1820)
                     /locus_tag="PC503_003532"
     CDS             complement(1383..1820)
                     /locus_tag="PC503_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2529482.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            1924..2922
                     /locus_tag="PC503_003533"
     CDS             1924..2922
                     /locus_tag="PC503_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF2529483.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(3042..3968)
                     /locus_tag="PC503_003534"
     CDS             complement(3042..3968)
                     /locus_tag="PC503_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2529484.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            4353..5957
                     /locus_tag="PC503_003535"
     CDS             4353..5957
                     /locus_tag="PC503_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2529485.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
BASE COUNT         2246 a          756 c          945 g         2085 t
ORIGIN      
        1 atattgcaaa tatgtttatg aaaaaggata ttaataaaga atttgacatt gattttattc
       61 tcagtaaaga agttatatgt aattatacca aagaaatatt tcaaaattta tataaaaaag
      121 aacaaagcat aggtaaaaaa gaactgctta tattgagcat aatagagaag tttttagtta
      181 aatctataat aacttttgaa gagttaaaat tgatagtgaa tataatagaa gaaaatttta
      241 catcaatata caatgaaagt ggaaagattt atttgtttag aaagtttgga gttccattcg
      301 tagtaggatg tctggattat aaaaaagtaa agtttgaaaa agatgtagtt aagattattg
      361 aggttgactt gacaaaagaa ataaatgata taagtataaa gttatcatag tgtattatct
      421 tatataatgt attataataa tctacttaaa atacacttta tttaaatatt tagtttaaag
      481 atgagatttt atgtgagtgt gtaaaagtta aagatagatt taagtaggtt atagggatta
      541 gtaaacaata aaatgaacca tgatgaacta ctataaattg tatttaaact acattttcta
      601 cttatagtaa tatcaatggt tcattttatt gttattaaga taatacagta tttataaaaa
      661 tacttgatat aaatatagta aattgtttaa atagaattat tgccttaatt tattcaaata
      721 atgagttttt aaaatctaag aaatatcctt gtggatgaag acatacagga caagctttag
      781 gagcttcttt acctatatgt atatggccac aatgtgtaca tatccattgt atatcttcat
      841 ttcttctgaa taaagtacct tcttctaaat cagtagcata tctaccaaat ctatcaccat
      901 gaactttttc tatttcagct atattttcaa ataacttagc tatagattca aatccttctt
      961 cacgtgctgt ttttccaaag tttttatata catcatccca ctcttgaagc tcattatgtt
     1021 gtgcagcttt aaggtgttgt gctgtcttgt catataaatc tacagggtat gctcctgata
     1081 tacttatatt ttcaccagca aattctttta atttagaaaa gaattgtttt gcatgtgatt
     1141 tttcttggtc agcagtgtaa ttaaataaag actctattat atataatcct tctttttttg
     1201 ctacagatgc agaaatattg tatctatttc tagcttgact ctcacctgca aaagctctta
     1261 ataaattttc tttagtttta ctatctttta aattcatatt ctacctctct atcacaataa
     1321 atttttacaa tatttgattc tttttattta ttattccaat aggagatata attatgctca
     1381 atttagtcag catttttaaa attatcatta atttttttta aaattctaag aaattcttgt
     1441 ttttcatttt ctgtaatatt atggtatgcc gtctctttaa cttgtgttga gatgctatta
     1501 aaagtatctt ctataagcag tgcctttttt gtaagcttta tatacgtgat acgtttgtca
     1561 tttgtacatt tttgtctttc taaatatcct aggtttataa gtttattaac caacactgta
     1621 acagtggatt tatcttttcc tattttagct gcaatttctt tcattgtaag tattccatta
     1681 ttttcataaa gtgcagttaa aatatttcca tgagtaggta ttaactcacc taaaccattt
     1741 ttactgagtt tattttcaat gaatttaatc atactagcct ttgttttact tatgaaatgt
     1801 acaatatatt tatcttccat aaattattct ccaatcttta atctatttaa attagtttga
     1861 cataaaacta tttataaact ataattagtt taacataaaa ctaaatgtat tgggaggaaa
     1921 tttatgaata aaaaatttaa atcactatat attacagaag aagaaggaaa ttttagaaga
     1981 aatatagttg aaagagaagt ggatacattg ccagaaggcg aagttctaat aaaagtaaaa
     2041 tattcttctc taaattacaa ggatgcactt tctgcaaatg gtaataaggg tgttacgaga
     2101 aagtatcctc atacaccagg aattgatgca tctggtatag tagaatctag tagttgtgat
     2161 gattttaaaa ttggagaaga agttttagta acaggttatg acttgggaat gaatacttct
     2221 ggtggttttt cagaatacat aagagttcct tctagttggg tagttaaact tcctaaaaat
     2281 ctttcactaa aagaagcaat ggattatggt acagcagggt ttacagcagc tttatctgtg
     2341 tataaattta tagattctgt agacaagaat atgggagatg tattagtcac tggtggtact
     2401 ggaggagttg ctgtaattgc aactaaaata ttgattaaat taggttattc agttgtagtt
     2461 tcaacaggaa aattagaaga acaaaaagaa gtattactaa acttaggtgt taaagatgtt
     2521 atacataggt cagaagtgga tgataactca ggaagacctc tgcttagacc aagatgggct
     2581 ggagtaatag atacagtagg aggaaatact ctagcaacag caataaagac aactaattat
     2641 tgtggagcag taacaacttg tggtaatgca ggaggagttg attttacaag ttcagtatat
     2701 ccatttatct taaagggaat tactttatat ggtatagatt ctgtggattg cccaatgaac
     2761 ttaagattaa aaatatggga tttattatca aatgaatgga aattagatga tttagatgat
     2821 atggtaaatg tagtatcatt ggaagagtta aatgatagta tagattcaat aatggcagga
     2881 aaacatgttg gaagaacagt agttgattta gaaaaaatat aggtgaataa atttataatt
     2941 aggattatag gttttaagca aaaatgagat acttgaaatt tacttgtgag tatctcattt
     3001 ttttatgtaa aaagatttat gtagatgttt gtgtaaaaag attattcatg aacaattaat
     3061 tcaaatacat ctggtcttga atagtgacct tctgaatcaa aatctagtct actaagtact
     3121 attttttcta ggtctaaatc agctattagc atttcttctt tattgaaaat aggacctgct
     3181 acatattttc caaaagggtc aactatacaa cttcctcctg gacacataat ttctggttct
     3241 gcatctagct ctttatagta gttaaggtca gttggataca tatttttttc aacatattga
     3301 ttgcatccaa ttacaaaaca tcttccttct aaagcaatat gcttcatagt tgcttgccac
     3361 tcttctcttg aatctgcagt aggggctatg taaagtttta cacccttagc ataaagagct
     3421 gttctagcta atggcatata attttcccaa caaatcaacg aacccatttt tccatatgga
     3481 gtatcaacta ctgtaagagt acttccatct ccttctcccc aaatacatct ttctgttcct
     3541 gtaggtttaa gttttctgtg tttaccaatt agcttacctt ctggagagaa aaataagttt
     3601 gtgcaataaa gggtacaatt tatatcatta ccatctcttt ctgttatacc cattgataga
     3661 tatactcctg cttcttgtgc tgcttttcct aataaatctg ttgtagcact aggaactggt
     3721 acagaattat catagtatct tttccaatct tctctacctt ccattgttct acttccaaca
     3781 acaaatccaa atgaaagacc tcttggatat gcaggtatga atgcttcagg gaaaactacg
     3841 atatttgccc cttttctacc agcttcttta attaatccta atgctttttc aacagttttt
     3901 tctaaatcca ttatgactgg tgacgcctgg acaacagcaa ttcttacatt tttattttcc
     3961 ttgctcataa aaacctccta aaaaatattt aaattttttg cattgaatag attacatgag
     4021 atgttatttg agaactaaga tacttatatt gtgaataata atgtaactgt atatttaaaa
     4081 taatacatca tgatttaaaa aattacaatt gtacagatat aattgagttt agatatttaa
     4141 atttaacaac ttataatatt ttttcaatta gtataaagcc tattaatttg tcttatttac
     4201 aatgaatagt atttacttct tggcaaacaa taattaaaaa taaaactttt atatgattaa
     4261 actctaaaga aaaagtttat aaagaagata atataattaa gcagaaaata atgaaaaaaa
     4321 tttattaaag tagacaacgt aaggagaatt ttatgaaaga aaaaatttat tacaatggaa
     4381 atatcatcac aatggaagat tcaatatgtg gagatgctat tcttataaaa gacaaaataa
     4441 taaaaaagat aggaacaaaa gaagaagtat ttgctttgaa aaataaagat acagaaatta
     4501 tagatttaca aggtaagaca ttgatgccat cttttataga ttcacatagt cacttgatag
     4561 cttttgctac tactctaaag ctagttcctt tagaagatgc aaccagtttt aaagacatag
     4621 taaaaaaaat acaggatttc aaagagtcga ataatataaa aaaaggagac tggataattg
     4681 gattttcata tgataataat tttttagaag aaaataagca tccagataag agtgtactcg
     4741 atagtgcatc ttcagaaaat ccaatactaa tttcacatgc ttctggtcat atgggagttg
     4801 caaatacatt ggggttaaaa cagcttggtg ttaccaatga aacacgtgac ccagaaggtg
     4861 gacatatagg tagagtagaa ggcagtgaag aaccaaatgg atatttagaa gaaaatgcat
     4921 tttttaatgt agcatctaaa ataaaacaac catcatcaaa tgagattttt aattcaattg
     4981 aaaaagcaca gaacatatat ctaagctatg gtattacaac agctcaagaa ggtttaatgg
     5041 aagaaaatca atttaacatt ttaaaagcaa tggcaaatca aaataaatta aaaatggatg
     5101 ttgtaggata tgtaaatttg aaaaaaagta agtctgtagc agataataat agggagttta
     5161 taaaaaaata tataaataga tttaaaatag gaggttataa gattttctta gatggttctc
     5221 cacaaggtaa gacagcatgg ttgagtagac catatgaaaa ttcagatgat ggttattgtg
     5281 gatatcctat atacaaagat gaagaagtag aaaagtttat agatatttca ctaaaagaaa
     5341 agatgcaact cttaactcat tgtaatggag atgcagcagc agaccagttg atagatgcgt
     5401 ttgagaaagt tttaaattta aaagagcaaa gtagtgaaaa tcatataaga ccagttatga
     5461 tacatgctca aacagtaaga gaagaccaga ttgatgatat gaaagtaata aatatgatac
     5521 cttcatactt tgtagctcac acatattatt ggggtgatat tcatatcaaa aaccttggag
     5581 aagatagagc gtttaagatt agcccactta aaacaactat agaaaaggga ttaatttaca
     5641 ctcttcatca ggatacacca gtaatagcac ctaatatgct ggaaacagta tggtgtgctg
     5701 tcaatagaat tacaaaaaaa ggtatacaaa taggagaaaa tgaaaagata agcccattag
     5761 atgctttaaa gggtgttact ataaatgcag catatcaata ttttgaagaa gataaaaaag
     5821 gttcaattaa agaagggaaa ttagctaatt tgataatctt agatgaaaac ccacttacaa
     5881 tcgaccctat gaaaataaaa gatattaaag tattgcagac tataagagaa ggagaagtat
     5941 tgtattcttt gaagtagatg aaagttagat attttataat ctataaaaaa tagttttata
     6001 taataagtta ggtagaatta aataagatta ca
//
LOCUS       DAMJWC010000127         6000 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMJWC010000127 DAMJWC010000000
VERSION     DAMJWC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6000
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.132"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(983..1534)
                     /locus_tag="PC503_003536"
     CDS             complement(983..1534)
                     /locus_tag="PC503_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529486.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1725..2687
                     /locus_tag="PC503_003537"
     CDS             1725..2687
                     /locus_tag="PC503_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF2529487.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            2982..4826
                     /locus_tag="PC503_003538"
     CDS             2982..4826
                     /locus_tag="PC503_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2529488.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            5148..5732
                     /locus_tag="PC503_003539"
     CDS             5148..5732
                     /locus_tag="PC503_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2529489.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKGLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         2342 a          591 c          924 g         2143 t
ORIGIN      
        1 catactataa tttaaatata aggagatgcc ctttgaaaat aaaaattaaa aaatatttaa
       61 tgctactaca ataggaacta gaactacact taataaatat acagaaatta gatttggctc
      121 aatataaaat acaaatatag aatttaggtg ttttttatga aaaaattttt atatgcttta
      181 tatagtttca ttgttattat agctaatttt agattaaaag aaaaaaatta taactttatt
      241 ttattagcaa tcttttttat attgctgtta attcaaaatg gagttttaaa aacaggttat
      301 caaaatagag ctacatttta tcaagataat tattttaata gagaggataa aaatgataag
      361 ataaaattta tgactataaa gatttttata tttttgtcat taccattatg ttttaatata
      421 ctattcaatt atttaacctc ttaaattata tttagatata ggagtcttat gataaaagta
      481 agcttatgtg ttatttgtag taaatataaa gtgcatatag tgataaaaca aaagtttcat
      541 ataaatgaag aaaaaaatat aaaataattt atttaactac ttaaaaataa actaaaaggg
      601 ataataaaat agcttttagg ttatggtaat aaaggtattt aaaaagagtg cataagcact
      661 ccaattgtga gaaatacata cacaaatcat tattacaaca atgaaaaatg tacatataag
      721 agacgttttg tatttgtttt aagtgataat attttaatac taactaaata attatcacaa
      781 tagtaaaaaa gaaaaaggag tattttgtac tccatttgtc aaaaatataa aacttttata
      841 taagcttatt ataacataat tgataaaagt gtaaagatat ataatgaatt tataaagaaa
      901 aataaaataa aaaagataaa tcctaatcaa aggatttatc tttttgtata gaaaataatt
      961 attctattat taaatggcat ggctaaactg gataataatt tattattact gctttcaatg
     1021 ttttttctcc ttgattatgg tatgtatgaa ttgattcagc tgaaaaacaa atagagtcat
     1081 tttctctaag ttgataaata gagtcattta cttctaattt taattgacct tctataatca
     1141 taatatattc ctgtgatttt tcagaatgac caacagatgt ataactatga ccttcttcta
     1201 attccatttg aaataattcg aagtttctag ttggtgtatt gggataataa caataaagac
     1261 gataatcttt attttctgaa acttgtacat ctatatcagt ttttgataca ataaaagttt
     1321 cattttgagg ttgttccagt attgcagtat atggaacatt tagtccactt gcaattttcc
     1381 aaattgtgtt tactgttggg tttgagtctc ccttttcaat ttgcgaaagc attactttac
     1441 ttacgccaga taattcagca agttgaccta gacttaagtt acgttcatta cgtaatctat
     1501 ttaaattttt agcaataaca gtattaatac tcatagtagc tccttaaaat gtaaattatt
     1561 gacaaatata atttacgaat gtataattta tttaacatta tttataattt acaaatgtat
     1621 aatataatga acgttaaata cactgtacat ccgtaatata aattatactg cataaagagt
     1681 tgtttttcaa cggatgatag ttgagagatt aagggggaat tgtaatgcgt gtacttaata
     1741 atgttacaga ggctataggc aatactcata tgttacattt atccaaaata gcagatgaat
     1801 ttggagttca aggtaatatt tatgcaaaga tggaatactt aaatccggga tttagtaaaa
     1861 aggaccgtgt agcattacaa atgattaccg aagcagaaaa tgcaggttta ttagttccag
     1921 gtcaagcagt tgtggaatta acaagtggta atactggaac aggactagca atagcttgtg
     1981 catgtaaagg atataaattt atagcgtgta tgtcaaaagg aaattctatg gaaagagcaa
     2041 gaatgatgaa agctttaggt gctgaagtag ttcttgtaga ccaaatgcct aattcagttc
     2101 atggacaggt atctggtgaa gatttggcac ttgtagaaat tgaggctcaa aaaatagcaa
     2161 aagaaagaaa tgcatttaga gcagaccaat ttaatttaga agcttgtaat catgcacatg
     2221 aaaagtatac agcagaagaa atgtgggaac aattggatgg aaatattgat gtatttgtag
     2281 attttcttgg aagtggtagt acttttgcag gatgttcaaa aacacttaaa aaacataatt
     2341 cttctatcaa atgttatgtt gttgaacctg aaacagcagc aatttattca ggtaaagaaa
     2401 taactgacca agggcataaa atacaaggtg gaggatattc tatggatttg ccattagtag
     2461 acaagaaact tattgatggt tatattcaag ttacagacga ggaggcaact gatgtagcaa
     2521 gaaaattagc taaattagaa ggtgtatttg caggattttc ttcaggggca aatgtatgtg
     2581 cagcaattaa gttgttaaag agcagtgaaa aaggaaaaaa tatagtttta actcttaatg
     2641 atagtggttt aaaatattta agtactgatt tatatgaaga attgtaataa tagcacaata
     2701 gttatgcaat gttttttaaa ttaagtatat agatttaaat tataaaaagt atctcaatgt
     2761 aatttttgaa agttataaag gagatacttt tttattttgt aaatatggag tatcctactt
     2821 ataagtatta agctatatag atattgatga ttagctatgc aataaaaaag agtatgtgtt
     2881 tttgcattta tacatcataa cttggaataa tacatattaa tgttctaaat gtatttaaaa
     2941 catatgataa aattagaaca aatagataca aggagataaa aatgcaaaag agaattttaa
     3001 gaaattttat atttacgggt aaaaatattt taagtaaact tgtttttata ataaaatata
     3061 attttagtac attaatttta tttgaattat ttcataaagg attagcctta ttttttatat
     3121 ggccatctat tagatatata tttgatattt taataaaaag tttacatata gtctacctaa
     3181 atatggataa ttttataaaa gttttgacca atcccatgtc aatagttctg ataatactat
     3241 cagttataat actagctttt tatgcatttt ttgaatttac ctctgtaatt atttgtttta
     3301 ataaatcgat aaaatatgaa aaaatagggt tatttgaact ctttaaaata tcatttaaga
     3361 actctataaa attgttatat cctaaaaata tactattatt tatatttgtg atattaataa
     3421 ttccattagt aaatacagtt ttaatttcag ggtttatagg aaaaatacaa ataccagagt
     3481 acatactaga ttatataaag tctgatataa ttttaaatat aatctatatg atttttcttt
     3541 taataatata tatttcggtt attagatgga tttttagcat tcatgagata actttaaata
     3601 cagaaaattt taaaagagca agaaaagaaa gtgttaatct tataaaggga aagattataa
     3661 gaacaattat ttattcatta atattatctt tagtagtagc tattattgga tatgcgattt
     3721 atcatagtgg aattatattt ataggcatat ggactaaata ttgtactgat atggaatttt
     3781 tgaagaatgt atttataaat agatgtattg catttgaaga atattttaga ttgattttat
     3841 caatattcat ttttatattg gacattggat ttatctcagc aacttattat caatataaag
     3901 gagtaaatat ttctaaaaat aatattaaaa aagagaaaaa atctatatca aaaattgttt
     3961 ttaatttagt attaatatta ttgatttctt atatagagtc agttgcattt tcttcacata
     4021 taaatggtat gtttaatacg tcattttcat tttatacaac agcaattgct catagagcag
     4081 gagctgaaat ggctccagag aatactttgg cagcaataga agaagcttca catgctaaag
     4141 ctgattatgc agaaatagat gttcaagaaa ctaaagatgg agaacttatt gtacttcatg
     4201 attcaaactt taagagaact acaggagtag ataaaaatgt ttgggatgta aattataatg
     4261 aagtaaagac atatgatgcg ggaagctttt attattatgg aaaaggttat tatgatgaaa
     4321 agtttgttgg ggaaaagata ccaacactca aagaaatgat aaaatattct aaaggtaagg
     4381 tgaaattatt aatagaaata aaacttaatg gacatgaaaa gggagacgta gtaaaaaaag
     4441 ttgttcagtt aattaaagaa aataattttg aaaatcaatg tatagttgca tctatggata
     4501 aaactatatt acaaaaagta aaaaaactgg atgagaattt attgacatgc tattttatgg
     4561 caattgcata tggtgatttt tcaaagttaa attatgttga tatatatgga attgaatcaa
     4621 cttttgttaa taaaacagta gtagaaaaga ttcataaaat gaacaaaaaa atcttcgttt
     4681 ggactgttaa tagtgacagt ttaattgaga aaatgcttga cctaaatgta gatagtatta
     4741 ttacagataa tccatacctt atagagagtg caatttattg gaagaaaaat ggatttatta
     4801 gtcaagtgtc agattattta ttttaaatat tctataattg tattatccag taaaagagat
     4861 attattaaaa tcaataatat ctctttttaa cataaataag gttgttaaat taaggttatt
     4921 cttataaaaa ttgtgcttat cagctataaa caaggaataa aagtgaaaaa attgctctga
     4981 gattattaca gttaaaagag ttttaagatg acagagagat agattgtcaa ctgtatattt
     5041 aataaatctt gttatttatt aaattttata taagtaaaat atataaatta ataaatctta
     5101 tgctagaata tatatgaaaa acaatataaa tttggaggat taaaaacatg acagagcgag
     5161 aaaaaatgtt ggcaggagaa ctttacgatt gtggtgatat tgagttgtta actcaatggc
     5221 ataaagcaaa aggcctagta agagattata accaaacaga ttcctcggat ttggaaaaaa
     5281 aagaaaaaat attaaatgag ttacttggtg gtaagggtaa aaacttatgg attactgcac
     5341 cgtattatgt agattatgga aataatattt attttggaaa taattgtgaa gtcaatatga
     5401 attgtacgtt tttagatgat aataaaatta tcattgggga taatgcacta atcgcaccaa
     5461 acgtacaaat atatactgca tttcatccaa ctaatgctgg tgatagattt ggtaatgcca
     5521 aagaagatgg ttcatttgaa ttttgtaaaa ctcaaacagc tccagttact attggagata
     5581 atgtttggat tggcgggggt gctattatca tgccaggtgt tactattgga gataatgtag
     5641 ttataggtgc aggaagtatt gttacaaaag atattccaag taatatgatt gcatacggaa
     5701 atccatgccg tattattcga gaaaataaat aaagttaaat tttcttgcaa aatctcaaaa
     5761 aacacctttc ttactttata catagggtat tttctaatac tttcacatcc atattcattt
     5821 gttaaatttt tgtggaatgt agtttttatc acttctatct tacatttcca ccattttttt
     5881 ataaaagtca ttcctttata gatttattta taatagtata tattctattt gatgtttgaa
     5941 taagcactta tttttaagta aaatactaac ttttaggtta gtattttgct atagtatgat
//
LOCUS       DAMJWC010000128         5948 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMJWC010000128 DAMJWC010000000
VERSION     DAMJWC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5948
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.133"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            127..939
                     /gene="modA"
                     /locus_tag="PC503_003540"
     CDS             127..939
                     /gene="modA"
                     /locus_tag="PC503_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2529490.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            949..1740
                     /locus_tag="PC503_003541"
     CDS             949..1740
                     /locus_tag="PC503_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529491.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAIILSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILYTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            1742..2437
                     /locus_tag="PC503_003542"
     CDS             1742..2437
                     /locus_tag="PC503_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2529492.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            2424..3155
                     /locus_tag="PC503_003543"
     CDS             2424..3155
                     /locus_tag="PC503_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529493.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            3469..4269
                     /locus_tag="PC503_003544"
     CDS             3469..4269
                     /locus_tag="PC503_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2529494.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            4809..5525
                     /locus_tag="PC503_003545"
     CDS             4809..5525
                     /locus_tag="PC503_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529495.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT         2312 a          720 c          841 g         2075 t
ORIGIN      
        1 ttttcttaac tatacataac aaaacataac aaaacattat aaaacataac aaaaacttag
       61 acatcgtttt cttagtatga tatactaaaa aagaatttac attaatttac taagggggaa
      121 tatcttatgt ttaaaaaact ttcagtacta gctttagcta tgattatttc attaagtatt
      181 actgcatgta attctaaaga aaacaaagct aatgatgaat ctaatactaa agtgacaaca
      241 gctgatgatt caaaagaaaa agagactctt tttgtctatt caggggcagg tttaaagaaa
      301 ccaatggatg aaatagcaaa aaaatttgag aaagaaaata atgtcaaagt tgaatatagc
      361 tatgcaggtt ctgcacagct aatagctcaa attgagacaa gtcacaaagg ggacgtattt
      421 attgttggtt ctgaaccaat ttattcaaaa gcctttgaaa aagaacttgt aggtgaacat
      481 aaaacggttg cacatcatac acctgcaata gttgtaccta aaggaaatcc agctaatatt
      541 caaaaattgg aagacttaaa taaagatgga gttaaactta ttttgggaga caaagagtct
      601 aatgctatag gtaagactac acaaaaaata cttgaaaaaa ataatttaaa atctataaat
      661 gataatgttg tctctacagc tgcaactgta aatgaaatga ttgtacagtt aacatcaagt
      721 aaagctgatg ctacaatagc cacaaaagat tcggtctttg gcaatgaaga tgtagaagtt
      781 atagaaattg cccaagataa aaatatagac caacttatat cagcaggaat cgtaaactat
      841 agtgataaaa aagatttagc taataaattt ataaattata tagagtcaga cgaagctaaa
      901 cagatattta aaaaatatgg ttttgaacct gttaagtagt gattaaactt gaaaaataaa
      961 ttttttacta ctctacttac tggatttttt gctatagtct ttttgtttat tgtatcacca
     1021 cttcttatgt taatcattaa agggataagt tatgttccta tatgcttaaa atcagtggaa
     1081 gtacagtatg caataatact tagtattaaa acatctttaa tatctactat agtatgcctt
     1141 ttattagcta ttccagtagc atatttttta catattacta aattaccatt taaaaaactg
     1201 attatacaga taataaatct ccctatgtct cttccacact tagtatcagg aattgctctt
     1261 ttacttttgt ttggaagaat ggggattgga gattccattt ataagatttt taagcttgat
     1321 tttatattta caaagcaagg tatagtttta gcacaagtat ttgtaaatct tccacttact
     1381 attaaaatac tttacacttc actaaatgaa agtaatgaaa agatgatatt tgttgcacgt
     1441 acccttggat gtaatagttg ggaagcattt agatttataa ttcttccaaa tctaaaaact
     1501 ggaatcatat ctgcaactgt aatgacttgg tcaagagcac ttggtgaatt tggtgcagta
     1561 gctatgatag caggttctac acgtatgaaa actgaaatta ttcctacatc tatatattta
     1621 aatatgtcta ctggtgatat agacattgca atcggaatag ctgtaatttt gatatttatc
     1681 tcacttacat gcttgatgct ttttgagata ttttttaata gagaggttga taagaattaa
     1741 tatgttaaaa ataaaaaatt tatctcttga tttacctaat tttaaattac aagaaaatag
     1801 tttaaatatt aataatcatg aatactttgt tttattagga gctagtgggt caggtaaaac
     1861 tctatttcta gaaacattag caggaagata tccatctgct aaaggaaatg tatcatacaa
     1921 agaaaattta atatcaaact tacctccaga aaatagaaat ataggatttg tatatcaaaa
     1981 ttttgaatta tttccaaata tgaatgttga agataatata aggtttccac ttaaattgag
     2041 aaaaatacct atagatgaac agattcttaa ggctaaccac ttatctaaat taatgcagat
     2101 agaagatata aaaaataggt atcctaaaaa tttaagtgga ggtgaaaagc aacgagttgc
     2161 ttttgcacgt gccttaatag ctgaacctga tatattactt ttagatgaac ctatgagttc
     2221 attggattat attacaaaaa aacatataag caaaattttg aaggatgtct acataaaata
     2281 caaaccaaca gtgattcatg ttactcatga tatttctgaa gcaatgtttt ttgctcataa
     2341 gataggaata atgaacaatg gaaaaataaa tcatattttt gatttaaatg aagaaataaa
     2401 aaataaagga gaatcttttt tctatgaata tatttgatat tttgagagat tatctattag
     2461 tacaagttga taaatataat ttaaatatgg atatgataag tattgtgtcc aaatctctat
     2521 cttcaaaaga agcaattgga aatactaagc gtaaagattt cccaattata gttggtaaag
     2581 aaataatgct tgaagctgac tttaaaggag ctaaaggaca agcatttact tctactccat
     2641 ctacatttga aggttcttta aaagacatat tatcattaga tttacatgac aatcctcatg
     2701 atagaagtct ttttatagca tcattaaatg cagttatgaa atacttaggc aagacggata
     2761 gaaccattca ttgtaaaaat aacgagccag agatatgtgc aaaaaaattc cctgagttta
     2821 taaaaatgga atttggtaat ccaaaagtag caattatagg atatcaacca gccataattg
     2881 ataatattaa ggactttttc gaaacaagag tattagattt aaatcctgaa tttgtggata
     2941 ctatccaata taatgttaag attgaagatg gtatacgaga ttatgaagat gtaatatctt
     3001 gggctgattt agtgatttgc acaggaagta cattatgtaa taactcaatt ataaattttc
     3061 tatcacttaa caaaccagtt tactattatg gaactacgat agctggtgca tcaaatattt
     3121 taggtttaaa aagactctgt ttttgtagta aataagcaat catatcatca aggagtacac
     3181 aaatatatat gtgtactctt taaatttaaa aagttattac ttttattcta agtactaaag
     3241 taaaattcta ttaaaatgaa tcccgaataa atgtacaatc cctttaaatc tcaattccta
     3301 tcaatcatta atattttgat tagtcttata cataaatgtt ttctttattt taaactaata
     3361 aaaaaatttt attccattaa tctactctat atttttcagc atttaagaaa taatttttag
     3421 tactttgttt gataatataa ctaagacaac ttttcaggag atgattaaat gacatttaag
     3481 aataaaaaat ttactataaa taaatataaa attctatcta ttattctagt tttatgtttg
     3541 attttaaccg cttttagtag ctatgtgaat tatagtcata aaaaatttaa agattatgtt
     3601 gtcttctatg ttcagcatca agatgatgaa gtgttgtggg ctgggagtgc tattgttaat
     3661 gctataaaag aaagaggaaa aaatcatgta tttgtggttt tagtatctac tggatgtggt
     3721 atatccgtct ttgataaata taaaaaatat gaaaacctaa caaatataca aaaatcagaa
     3781 tatagaaata gagaattttt agcttctctt aatagccttg gtgtaataag ggaaaatata
     3841 atattattac cagaaacaaa tacaaatggt aatactgact tcaattacat ggaaaaaatt
     3901 gctcttacat ttgaagaaaa atttaaaaat gtaactcata tagcacatac ttataagtta
     3961 gatgaccatt tacaacattt aaaaaatggt tctgttatcc aaaatttata taatgctggt
     4021 aaaataaaag atgctaaata ttttgtaaaa cctaaatttg ctgataaaat aacttttaat
     4081 aataagatag tttataaagc tcattctact gaagactatg aaaaggttaa aaatgcctgt
     4141 caacaataca aaattgttga tgaattagaa tatagagaag gtattggcta taagtctgac
     4201 cataaatcat ttgataagtt attaaataat aaagatgttc ctgctatact tcatacacct
     4261 aatttataag aaatatttat tcttttaatt taagttataa aaaggaaatt atttgagatt
     4321 ttgtgatata gcactttttg tgctatacta ctttttctca tacaactatt acccatatct
     4381 aatttcatca tctcttaaaa tatataaaga tatcatcatt aaaacctata agccttatta
     4441 aatgctttat acatatctac attaagctac ctatttatat taaactacat taaaataaat
     4501 atttgttata aattcttaat aattatgaaa ctcatttgtt atttatattt gttaatatat
     4561 gtttaaacct aaaaaattaa taaaccaaaa taacataagg agtgtgatag attaccctag
     4621 atattttcat aaacttttac cttcagatta atatgggcgt ctatactttt aaatttacta
     4681 tatgcattga caatatatta aaagtactag tttttatttc ataatgaacg ggcttactgt
     4741 tttctaatac ctctttttgg tataaaataa aaattggtta aaaataaaat ttcaaggggg
     4801 ttaataagtt gaatcaaaat atattggttg tagatgatga tagagagata gttgatgcta
     4861 tagagttcta tttgagacct gataacttta atgttttaaa ggcatatgat ggacttgaag
     4921 cattggacat actaatcgaa aatgatatta agttaataat aatggatgta atgatgccca
     4981 atttagatgg gcttaaaact acacttaaaa taagagaaaa aaggaatata ccaataattc
     5041 tcttatctgc aaaatcagaa gatatggaca aaattatagg tcttaatatg ggtgctgatg
     5101 actatataac taaaccattt aatccactag aacttactgc tcgagtaaaa tctcaactta
     5161 gaaggtatat aaatttaggt gattttagta atacaaataa ctcaaatgat actaattata
     5221 ttctaaaaag tggtggccta gagctaaata cagatacaaa aatagtttct ttagatggtg
     5281 aagaaattaa aatgacacca cttgaatata aaatacttac acttcttatg tcacgaaaag
     5341 gtaaaatttt ctcttctcat gagatttatg aaaatgtctg gaatgaggat gcttatagtt
     5401 gtgagagaac tattgctgtt catattagaa gaattagaga aaagattgaa attaatccaa
     5461 aagaaccaaa atatttaaag gtggtgtggg gcattggtta caaaattgaa aaacttaatt
     5521 attaatgatt ctaaagcaaa atttatttta ttattattac tgtttctatt agtttctata
     5581 ttatttgaag cagtttatga tttgaataat aacttttctt ataatattaa ttattattat
     5641 aaagagtttg ctctccctta tttttatttt ttcggtactc ctgtacattt gtcaaaagta
     5701 gaattagagt ttgtctgcat aggtattata ttatcaagtt ttttattgac tatactatgt
     5761 tttacattgt ataaaaaaaa taaacagact aaagtcaaat tcttagagaa tgtcataagc
     5821 cttttttcta aggtaaaaat agaacttaca cttatattaa ctttgatact attaacctta
     5881 aggtttcatg catttacaag taataaaatg ttttacaaca ctaatttaat aatctacaat
     5941 tttataat
//
LOCUS       DAMJWC010000129         5863 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMJWC010000129 DAMJWC010000000
VERSION     DAMJWC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5863
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.134"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            901..2571
                     /locus_tag="PC503_003546"
     CDS             901..2571
                     /locus_tag="PC503_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF2529496.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2693..3427)
                     /gene="pflA"
                     /locus_tag="PC503_003547"
     CDS             complement(2693..3427)
                     /gene="pflA"
                     /locus_tag="PC503_003547"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF2529497.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNIDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3587..5818)
                     /gene="pflB"
                     /locus_tag="PC503_003548"
     CDS             complement(3587..5818)
                     /gene="pflB"
                     /locus_tag="PC503_003548"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF2529498.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
BASE COUNT         2123 a          836 c          828 g         2076 t
ORIGIN      
        1 gatatgtata tttttatagc tattttatta taaaaaaaaa gaaccctttt ataacaaatg
       61 gaaactatgg atgtaataat taaaataaaa aatattattt tatatttata aacattgaca
      121 ttctaatttt gtagtgtaat cgtatttttt attaattctt acaaaatcaa tgaaaataag
      181 tatatccatt ttaaagtaca taaatttaaa aatccagaaa aatatactta aattatgtaa
      241 gtaaaagagg ggttgaatca gttgaaaatg taatattagt aaatagtaca tcaatcctat
      301 ataccctgta agcaactcta ttttcatgta ctaaaaatgt acctatttta ttaactgaaa
      361 agaataaatt aaatgtaagt acataagaag atagaaaaaa ttaaaaacaa aaaatattta
      421 tataaataaa tataaaaaat gatataatcc ctattaaaaa atttatagat gatgaagaaa
      481 tatcaaaatc ttatattata ggaagagaca cttctttgcc aaaatctata gaaaagcaat
      541 accaaatcca aagagaatag gcgaagaaaa aaataaaata aattcaagag taatagaaaa
      601 gttttataga ataaagaact gataactctt tatataacga aaaatagaat tttaagagaa
      661 aatgatttaa taaatgattt aacatggtgt tttagcaggt aaaaataaat caccagtaat
      721 gattatagaa aaattacttt atgaatctca aaaaacttag ttaagagtaa gagatttgat
      781 aagataacta aagttgggga aatgtgtttg atgagacaaa aaattagtaa aatagtataa
      841 tctaaataag gatattttgt tgattaaact acactaatag taatattgta gggggaaaag
      901 atgagagaag aatcgaactc tttaagttta gaccatatag aaattttctt tgaactttta
      961 tctcaaagta cagaagatta tatatttttt tgggatataa ataggaataa atttaaaatt
     1021 tcttcagcaa tttttgatga atttaactta agtaaagaga tagaatctga tttggtcaat
     1081 tgttggagta aaattgttta tccggatgat gttcaaatat ggaaagatga tatacaagaa
     1141 ttactacatg gaaaaaaagg tgagcacaat ttagaatata ggttgattaa taaatataaa
     1201 gaaatagtat ggatttcttg tagaggtaaa gtttatgtgt cggatgaccc aaaaactata
     1261 tttctagtcg ggagaataaa gaatattggt gaaaaaaata aatttgattc tatcacagga
     1321 acgtggaata gagaacaatt tgaacataga atgaattatc ttataaaaga gaaaatttat
     1381 aaaaatggtg ctatgtttat tatggatatt gataatttta aaaatataaa tgaaaaatat
     1441 ggacattctt atggtgacaa agtattgcgt gcaattgcta ctgaagtatt agaatatctt
     1501 ccaaaagatg taagattgta taggttagat ggagatgaat ttgcattttt ttaccctatg
     1561 tgtactaaag aaactataga gaaaatatat gaaaagatac agatgtatac aaatactcag
     1621 catgaaattg aatcaaataa gtactattgc acagtgactg caggcgttgc tatgtatcca
     1681 gaagatggag ataattattt agatttattt aaacatgctg atattgcatt ggatatagca
     1741 aaaattagtg gtaaaaatag aattaagttt ttttcacaag agctctatga aaataaacta
     1801 aaggtaattt caatgcaaca aaaactaaga gagtgcgttg aaaataattt taatgatttt
     1861 gagttgtttt ttcaacccca ggtaaatgct gttacaaaag aggtaatagg ggcagaggta
     1921 cttttaagat ggcattcgag tacttatgga gaagtatctc ctgttgaatt tataccaata
     1981 ctagaacaga gtaatttaat tataccagtt gggaagtgga ttataaaaga agctgtaaaa
     2041 cagtgtaaag aatggcataa aataaatcca gactttaaaa tatctgtaaa tgtatcgtat
     2101 attcagttaa aggaagattt ttttagagat tttatagtag aatgtttagt agagtatcaa
     2161 ttaagacctg aatttttaat tttggaatta acagagaatt gttggatacc agatataaat
     2221 ttactaaatg ataaatttat tagtttaaag ggtataggag tatatattgc aatagatgac
     2281 tttggtacag gatattcatc tttaaattac cttaaagaac tgtctgttaa tataataaaa
     2341 attgaaagaa gttttgttaa gaatattaca tataatagtt atgaatatac ttttcttgaa
     2401 tatattatta aattagctca tattataaat ttaaaagttt gtgttgaggg aatagagtct
     2461 tatgaagagt atgatatagt aaaaagctta ggtgtagata ttattcaggg ttttttattt
     2521 ggaagacctg taagtgcctc tgaattttat aaatttcagc tatcaaagtg atgtatataa
     2581 aatgagatat atagtatata aaaatagggc aaagtggaag ttttgaagtt tattaaaaat
     2641 ttacacttta ccctattttg ttatgtcttc tataaaggat taatatacta cactaactat
     2701 tatatacttt cactccaaat ttagagatta tttcactagc tttttggaca tcttccttag
     2761 tggcatcagg aacatctttt agttcataat cgatacctaa actttcccat ttgtgtattc
     2821 ccatagaatg gtatggtagc aattcaaatc tttctacatt tttcaatgta gctacaaatt
     2881 gacctagttt ttctaaatta tctatatcat cagtaatgcc aggaactaaa acatgtctta
     2941 tccatacagg aatatttctt gattctaagt gtctagcaag ttttaatgcc ttatccatac
     3001 caacaccagt caaatcaata gatttttcct caaccatatg ttttaaatca agtaaaacca
     3061 aatcaatatt atctaaaact gggtctatag tttctatatc tacaaatcca gatgtatcca
     3121 agcaagtgtg tatatcattt tcttttgctt ttttaaataa ttcacttaaa aattctggtt
     3181 gaagagtgga ttcaccacca gaggcagtta tacctccacc agaaaacttc ataaaagaag
     3241 tatacttaag agcatccgtt attatttcat caactgtgta ttcttttcct gatttaatat
     3301 cccatgtatc cctgttatga cagtatttgc atctaagagg acacccctga aaaaataata
     3361 tatatcttat tcctggtcca tctacagtac caaacgtttc tatagaatgt atctttccct
     3421 taatcataga gttcacctca caatatattt taataacctt atcaatagtt ataatatttc
     3481 tctaaaaaag gccatcttat accagaaata attcaaatat aagatagcct tttattttta
     3541 ttttttacac agtagtaatc ttagttaaag tataaaaatt taaagactaa gccattttac
     3601 cgtggaatgt tctgtttata acatctaatt gttgctcttt agttaatttt atgaagttaa
     3661 ctgcatatcc agatactctt atagttaatt gtggatattc ttctggatgt tccatagcat
     3721 cttctaaagt agctctatca aatacattta catttaagtg atgagcattt tgagcgaagt
     3781 atccatccat cattgcagaa agattgttta ttctttcagt catatctttt cctaaagcac
     3841 caggtactat agagaaagta ttagatatac catcttgagc atgttcatat ggtaatttag
     3901 caactgaaga taatgaagct aaagcaccat tagtatctct accatgcatt gggttagcac
     3961 caggagcaaa tggagcacca gctcttctac catctggtgt attaccagtt ttcttaccat
     4021 aaacaacatt tgaagttatt gtaagtatag attgagttgg ataagaattt ctataagttt
     4081 tattctttct tattttattc ataaagcttt caactaactc tacagctata ctatcaactc
     4141 tatcatcatt atttccgtat tttggataat ctccttctat ttcaaaatca acagctattc
     4201 cttgttcatt tctaatagtt ttaaccttag catgttttat agcagataat gagtctgcac
     4261 aaactgataa cccagccata ccacaagcca tagttctaaa tatatctcta tcatgtaatg
     4321 ccatttctaa tgcttcataa gaatatttat catgcatata atgtattaca tttaaagtat
     4381 ttacatataa tgttgctaac caatcagtga atggttcaaa tttactcata acttcatcat
     4441 aatctaagta ctcagaagtt ataggttcaa atcttggtcc aacttgaaca ccagatttct
     4501 catctacacc accatttata gcgtataata aagttttagc taagttaact ctagctccaa
     4561 agaactgcat ttgtttacca attctcattg cagatacaca acaagctata ccatagtcat
     4621 ctccccagta tgctctcatt aaatcatcat tttcatactg tactgaactt gtatctatag
     4681 atactttaga acagaaatct ttgaatcctt gaggtaattt agttgaccat agaactgtta
     4741 agtttggttc tggagaaggt cctaatgtat atagagtatt taacattcta aatgagtttt
     4801 tagtaactaa tgttctacca tctattccca tacctcctat acactcagtt acccaagttg
     4861 ggtctccaga gaataggtta ttgtaatcag gagttcttag gaacttaacc attcttaatt
     4921 tcataacaaa atggtccata tactcttgta attcttcttc tgttacgatt ccagctttta
     4981 aatctctttc aaagtatata tctaagaaag tagatgttct acctaaagac attgcagcac
     5041 cattttggtc tttaacagca cctaaataac caaagtataa ccattgtaca gcttcttttg
     5101 agttagttgc tggttttgat atatcaaatc cataagattc agccattttt ttaagttcat
     5161 ttaaagctga tatttgctca gttatttctt ctcttaatct gataacttcc tcatccatgc
     5221 aagaaacttc taatgatttc ttttgctcat ttttatcttc tattaaagca tcaacaccgt
     5281 atagagcaac tcttctgtag tcaccaatta ttctacctct accataagca tctggaagac
     5341 ctgttattat accagatttt ctagcagctc tcatttctgg agtataaaca tcaaaaactc
     5401 cttggttgtg tgtttttctg tatttagtaa atatatcttt tatttctggg tctaattcat
     5461 atccaaaagc ttcacatgaa ttttcaacca tctttatacc accatatggc atgacagctc
     5521 tttttaaagg ggcatccgtt tgtaacccaa ctattgtttc taattcttta tctaaatatc
     5581 ctggagcata tgcagctatt ccagaaacag tttttgtatc aacatctaaa gtaccaccat
     5641 tttctctttc ttttttaaat aggaccattg cttcgtccca taatttttta gtattttcag
     5701 tggcaccagc taagaaagag tcatttccct catatggaga atagtttaat tgtataaact
     5761 ctctaacatt tatttcttta gtccatcttc ctgttttaaa tccttgccat gcattcatta
     5821 agtatttcct ccttagattt aaatgataaa taatactatt aaa
//
LOCUS       DAMJWC010000130         5839 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMJWC010000130 DAMJWC010000000
VERSION     DAMJWC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.135"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(322..2154)
                     /locus_tag="PC503_003549"
     CDS             complement(322..2154)
                     /locus_tag="PC503_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529499.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(2147..4393)
                     /locus_tag="PC503_003550"
     CDS             complement(2147..4393)
                     /locus_tag="PC503_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529500.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(4461..4922)
                     /locus_tag="PC503_003551"
     CDS             complement(4461..4922)
                     /locus_tag="PC503_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2529501.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            complement(5227..5793)
                     /locus_tag="PC503_003552"
     CDS             complement(5227..5793)
                     /locus_tag="PC503_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF2529502.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         1867 a         1086 c          634 g         2252 t
ORIGIN      
        1 atatacttca atataatcat caactattaa aattaaattc tatttataat aaaatttaaa
       61 gaataaaatt aaatatacat tttgataatc acctccaaca ttttccttac tacatattat
      121 aataaaataa acactttgta aagacataaa attatgtggc tatctcaaaa tatagagaat
      181 cctctttttc attgttaaaa tgataaaaat acactttatt tcatacacaa aagagtgcct
      241 tatgaattaa aaagttcatt ttaaggcacc ctcatttatt ttatcttatt aattacatgt
      301 ctatgctaag atagtttttt gttacattgc ttcatcttct tcaaattgag aattgtaaag
      361 attggcatag aatccgcctt tctttagaag ttcctcgtga tttccttgtt caactatatc
      421 tccttcattc attacaagaa tcatatcagc atcacgtata gttgataatc tgtgggctat
      481 aacaaaactt gttctacctt ccataagatt atccatagct ttttgaatca atacttctgt
      541 tctagtatcg acagaacttg tagcttcatc taatattaaa attttaggat cagctaaaat
      601 agcacgagct atagtcaata attgtttttg accttgagaa acattacttg cttcttcatt
      661 taatttcatc ttatatccat ctggtaatgt cttaataaat ctatgaacat gtgcagattt
      721 agcagcctct ataacttctt catctgtagc attcaactta ccatatctta tattttccat
      781 aattgaacca ctaaataacc atgtatcttg aagaaccata ccaaacattt ctctaagctc
      841 actacgatta aaatctttaa tattatgacc atcaatcagt attgaaccgc tattaacatc
      901 ataaaatctc attaacagtt taactattgt agttttacct gctcctgtag gtccaacaat
      961 agcaactttt tgaccaggtt taacatttac tgagaaatca tttattatag tcttgtttgg
     1021 gttatatcca aagttgacat tttcaaaatc aattttacct tctaaaccat ctattgaaac
     1081 tgcattttca acaatttgga cttcttcttc ctcttctaaa aactcaaata ctctttcaga
     1141 agctgctgct gttgattgca ataaattggc aacctgtgca atctgagtca ttggctgtgt
     1201 aaagtttctt acatattgta taaatgactg tatgtcacca acctcaattg ttttcttaat
     1261 tgcaagccaa cctcctaaga ttgataccat tacatatccc aagtttccaa taaacatcat
     1321 aagtggttgc attatacctg ataaaaattg agatttccac gctgaattat acaggctatc
     1381 atttagttta tcaaactctt caattacttc atcctcacga ttaaatgctt ttactattgt
     1441 ttggccactg taagtttcct caacttgacc atttacattt cctaaatatt cttgttgata
     1501 tctaaagtat ttttgtgatt tctttattat tcttgaaatt acaaacattg atattggtaa
     1561 tattaaaact gccactaatg tcataattcc acttatagat aacatcatta tcaaaacacc
     1621 tatcatagtt gttactgatg ttataagctg tgtcatactt tgatttaaac tttgatttaa
     1681 agtatctata tcattcgtaa ttctcgataa tatttcacca tgcgtcttag tatcaaaata
     1741 cttcattggc aatctatcca attttgctga aatctctttt cttaaattat aggatacttt
     1801 ttgagaaatt ccactcatta taaatccttg tataaaagag aacagtgcac ttatcaaata
     1861 aaggaaaagt aaaaaggtta agatttttcc aattgcatta aaatctatac ctacgtttcc
     1921 tccagaaact ttactcacta gcccttcaaa tatctttgta gttgcctttc ctaaaatttt
     1981 tggacctact atagaaaacg acgcactacc aatagcaaat acaattacta gaattattga
     2041 tattttaaat ttagataaat atgcaattag ttttcgcata gtccctttaa agtcatttgc
     2101 tttttgtcct gctcccatag attttcccat aggacctctt cccattctac tcattagcta
     2161 gctcctcctt tgaaagttgt gataaagcta tttgctcata aacttcgcaa ttttttagaa
     2221 gctctttatg tgttcctatt ccaactattt cgccctcatt taaaacaatt atctgttctg
     2281 catttaagat agtactaatt ctttgtgcaa ctattagaac tgtactttca gcagtttttg
     2341 attttaaagc cttacgaaga gctgcatcag tttttaagtc aagtgctgaa aaactatcat
     2401 caaatatata aacttctgga ttttttgcta ttgctcttgc aatagaaagt ctttgttttt
     2461 gacctccaga tacatttgtt ccaccttgag aaatttcagt tttaaaagct tccggtttag
     2521 aatctataaa ttctgtagct tgagctattt cagctgctgt tctcatttct tcatctgttg
     2581 cgtcttttct accatatttt aagttggatt ctatagtacc agaaaacaat actccctttt
     2641 gaggtacata tccaattttt tcccttaaat catgttgaga aacatttttt atattaactc
     2701 caccaagtaa tatttctcct tcagtaacat caaagaaacg aggaattaaa tttataagag
     2761 ttgacttacc actaccagta cttcctataa aggcagttgt ttctcctggc tttgctgtaa
     2821 aagatatatt tgttaatata ggttcttctg cgtctggata catgaacgaa acatttttaa
     2881 attcaacaag acccttttta tcttccttaa actcttgtgc ctctgatttt tctgggtctt
     2941 ttatgcttat atctgacact aatacttcat ctatacgtgt agctgaaacg gatgctcttg
     3001 gaagcataat agataccatt gatatcatta agaatgacat tattatttgc attgtatatt
     3061 gtataaatgc catcatatct ccaacttgca ttgctccaga atcaacactg tatgcacctc
     3121 tccaaactat aagaactgtg ataaggttca ttataagcat catagcaggc atcatacatg
     3181 tcataactct atttacaaaa agatttgttt tagttaaatt tttatttgct ttatcaaatc
     3241 tttcttcttc atgtttttca gtactaaaag ctctgataac tggaatacca gtaattattt
     3301 cacggcttac taagtttaac ttatcaacaa gcttttgaac cagtttaaac ttaggcataa
     3361 ccactgagaa taacactaca attaatgata agatagcaac tactgctact gctataatcc
     3421 aggccattga agtatttgtg tttaaaacct ttatcactcc acctatagcc attataggtg
     3481 catagaatac tattctaagc aacataacca tcaacatttg tatctgttga atatcatttg
     3541 tactacgagt aattaatgaa gctgtagaaa attcattcat ttcagtattt gaaaatgaca
     3601 taacttttct aaatactcca cttcttaaat ttctacctac acttgcggct actcttgctg
     3661 ctaaaaatcc tactgttatt gtagctacca tactaatcat tgctatacca agcattttag
     3721 caccagtaaa taatatataa ttattttgag ttttttctgt atcaatacct attttctcat
     3781 attctgacct tacatatgaa acagagcttt gtgttatcat actctctggc atactttcaa
     3841 agcctttgct catctcttta gtcaatgtat ctaactgttc ctttggcatt gctgataaca
     3901 atttaaatat atcaacatct ccactttgag tagcttgtgg tggaagtttg ctcattaact
     3961 gagctttcat agcttttacc tctttactat cgccctcaag ccctgatact attaaaatag
     4021 ctttaccaaa aataacattt aaatcatcta tagtgtcttt gtctttagta tttaactcat
     4081 aaagagattc atcttttaga cctggatact tatctttata cttaacataa tcctttttat
     4141 tcagcaaagt ataattatct agtactttat ccttactact tttatccata aataaagtaa
     4201 ttttatttaa ttcactctct ctaatcacag atggaacaga gttttctact ccaccttgtt
     4261 gtatacctac atttactata ttggatgtgt attctggtaa agaaaggtca cataccgctt
     4321 gaattaccaa tagacagact attattacta ttgataatgc cgatttcttt aaatatttaa
     4381 ttaatttaaa catacatttc ttcccttctg taatattaat tagtctaata acattaaatt
     4441 gaaaaacatt attttaaact ttaaaaatat ttttcatctt catgcttatg acatcctgct
     4501 tttaaattat ctcgtacttg cattagaagt cttctaagta ctattttttc ttcttcacta
     4561 aatcctaaaa aaaactctct ttccaattcc ttgttaaatt cttcaacttt attacatatt
     4621 tctaaacctt tgtctgtcaa aaaaatccta gatactcttt ggtccttttc atcttgtttt
     4681 ctttccacaa gtccagcttt ttccatcctc tttatcataa ctgtagttgt agatgctttt
     4741 actttccttt tatctgctaa ttctttttga ctttgcccat ctttcatctt taaagaaaaa
     4801 agtatttggg gttgaccatg atataagcct aatttatcaa aataaaaatg agttcttata
     4861 aaatatattc gcattaattg caagaaaaca tcatttaatt tttcttcaga attgctattc
     4921 atacttgccc tccttatttt ttatattact tagtcggcta agcattattt tactatactg
     4981 catgcatttt ttcaatatat ttataaaaaa ttcatataaa tttcatttat taaatatttt
     5041 tatatcatat agttataatt ttaataaata atagtaagat ttttaattag tcagctactt
     5101 atatttttta ttgtaaagct taaaataaac cttttcatat attttcaaat aaaaaagttg
     5161 tcccaaaata aattttgaaa caacatcata ttcaacagta tcttgattat ataacattat
     5221 gatactctac ttatcttcat atccatttac aacaacgtct aacttcccag tttcaggtga
     5281 tataattaga ccatgtacaa taataccatc tggaattaaa ggatgccctt ttattaaatc
     5341 aatactatct tttacagatt cttctgcaga atcgaatcca tgtaaccatt gttttgtatc
     5401 aattccagca ctacgaagtg taagtattac atcattagat attcctctat ctaaaatttt
     5461 accaagtaac ttatccgtat caacattaca cataccacat ccatgatgcc ctacaaccat
     5521 aacctcatct acatcaaatt cgtaaattgc aactaaaaca cttctcataa tacttccaaa
     5581 aggatgcatt atagtagctc ctgcattttt tattagtttc acatctccat ttttcaaatt
     5641 catagcctta ggcaaaagct cagttaatct tgtatccata caagataaga ctactatttt
     5701 tttatttgga tgttttgatg tcacatattg ttcatattct ttgttctcta caaatgattt
     5761 attatattct aatatctctt caagttttct catatgtaat atcaccctct ttaaaaattt
     5821 ttttattatt atatcacta
//
LOCUS       DAMJWC010000131         5556 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMJWC010000131 DAMJWC010000000
VERSION     DAMJWC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.136"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            147..1328
                     /locus_tag="PC503_003553"
     CDS             147..1328
                     /locus_tag="PC503_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2529503.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(1470..2387)
                     /locus_tag="PC503_003554"
     CDS             complement(1470..2387)
                     /locus_tag="PC503_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529504.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            2640..3434
                     /locus_tag="PC503_003555"
     CDS             2640..3434
                     /locus_tag="PC503_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529505.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            3435..5495
                     /locus_tag="PC503_003556"
     CDS             3435..5495
                     /locus_tag="PC503_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2529506.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         2123 a          629 c          917 g         1887 t
ORIGIN      
        1 tgtttttgtg tataattata acaatttaat ttatattaat gcacttaaat ttgaaataga
       61 atgcttatag tggtaaaatt aattattaga atattagaaa taataaataa ataatacatt
      121 gtacttaaaa gggggagaaa tttaagatga acaaaaaata tattaaagca gggaatttaa
      181 ttgatggaac cggaaatagt attatgcaaa ataagggtat aattattgat ggagatacta
      241 tagttgaaat tgaagatata agagatgatt taaatggata tgatgtgtac gattacttag
      301 ataaaactgt tatgccaggc attatgaatt gtcatgttca cttgacaatg gagccagttg
      361 gaaatccaaa gatatattat gataatgtat cagatgtaga gcttgtagta aatacgataa
      421 aacaacttga tgcttatttg gattcaggag taacatatat tagaagctta ggttgtccca
      481 aatatgtgga tgtacaactt aaaaatctta tagacaaagg gtctatagat ggtcctggta
      541 tagttacttc aggtccagtt atatgtatga caggagggca tggatattat tttggtattg
      601 aaagtgatgg agtagatgaa tgtagaaaat cagccagaac agttttaaaa aatggagtag
      661 attgtgtaaa gataatggca actggaggtg taacaactga tggagttgag ccagggtcac
      721 cacaattaac tttggaggaa atgaaggctg ctgtagatga agctataaaa gcaggtaaaa
      781 taactgccac acatgcacaa ggaagaactg gtataaaaaa tgcagtgctt gcaggaatta
      841 cttctataga acatggtgtt tatttagatg atgaaataat tgatttgatg cttgaaagag
      901 gaacttactt agttccaact gtggctgcac catattttat tctaaatgca ggaaaagaaa
      961 gtggaataac tgaagctact cttagaaagt gtgagattgt tgccattcca cacaaagagt
     1021 cattcctaaa agcatataaa aaaggaatta aaattgcagt tggttctgat gcaggaactt
     1081 cttataatga acatggaaaa acatattatg aaatgaaact aatgtcagat tatggtatgg
     1141 ataatatgga tataatagtt gctgctacaa aaacagcatc tgaactttta agaattgata
     1201 aaaattatgg aactctagaa aaaggaaaga aagcagatgt tatagttgta aatggaaatc
     1261 cagtagagaa tatagacgta cttgcagatg tgttagcagt atttaaactt ggtaaaaaag
     1321 ttagataaat agtataaaaa taaaaaagag tgtctaaaga aatttttaaa taattataga
     1381 cactcttttt tattagtaat aattaaatct tttatacttt agaaaataga ttctatttta
     1441 tatttagata taactcttta aaatcattct tatgcaatat aatctataga atctacacat
     1501 acaaagtata ttcttgaatc attagaattt ccaagtacta taacatcatt tttcttacct
     1561 agaacttcaa caccagttag aaccaaacta ccagctacta cagtaacttg attatttata
     1621 tttgacatat aaagattatc taggatacct ttattacaac agcaatcatc acaatcgcag
     1681 ttgcaattac attctttgta atgtttttta tcaagatagt aacctaaaga tgctatgaaa
     1741 tcttcataat ctgcaggtgt aatatcaaat gcaacagctt taagattaca caatgatgct
     1801 aaatctacgt ttgctaatgg agtagatgca gcaagtataa aatcaattat agcagcaagt
     1861 attgcatcta atatagcccc aaggtctatc gtaggaggaa taactgcatc aataagtgca
     1921 attaattcag ctactcctgg tatagttcct atagtattaa ttaatccctc aagagttaaa
     1981 gggactggaa taggataaga tactctacca gctatatcta ttaaatcaca gttacaagca
     2041 gaaaatcttt caaaagtacc atcaagtcca gataaattat cttttggagg agctgaaaga
     2101 tctataccta ccaaattagc acctactata aagaaatctg agataaaagc aaattgatta
     2161 aagtttacaa aaggtcttag agcatcatat cttagaagtt ctaatgcttc tctcatactt
     2221 tttttacaac aacattgttt tattttaggt tctttatatt tatttggata attatagtat
     2281 ctatcagcta cttgataatt ttcatagtat ctttcatttg tatttggata atcttcctca
     2341 tattcttgtg taaatctaaa gtcctctcta catttattat tttccactaa atacactcct
     2401 tttatatttt aatttaaatg tatagataat taagcttatc tatatagtaa tattatattt
     2461 ataatgtaaa aaaatgttac aaaagatatt ataaacgaat aaaaaataat aatttgtcag
     2521 ataaacttgt aaatttttat gaataatcca ttctaaaaca aaaaactgtg tataaaaaag
     2581 gtttatatgt tatatttata taaatataac atatgaacga gaaaggagtg gtttgataaa
     2641 tgattgaggt agataaattg tgtaagtctt ttacaagggt tgtaaaagat gataagaata
     2701 aaagttcaat aagaaagcta aagaaagtaa aaactaaaaa agaagaattt tttgctgtaa
     2761 ataatgtttc atttaaagtt atggaaggtg aaattgttgg aatattaggt ccaaatggtg
     2821 caggaaagac tacattactt agaatgttag gtggcatatt aacaccaaca tcaggaagta
     2881 taaatatttc tggatatgat tattcaatag atagaaattc agcaaaaaaa gaaataggtt
     2941 atctctctgg aaatacaaaa ctatatggaa ggctttctcc gagagaactt ctaacaactt
     3001 ttgcaagtct atatgagatg tcaaaagaag atatagaaga atcaattgaa aatattgtaa
     3061 aaataatgga tatgagtgaa tttatagata atagaattga aaatctatca actggtcaga
     3121 ctcaaagaac atctatagct cgttgtttaa tacattctcc aaaagtatat atttttgatg
     3181 agccaacact aggtctggat gttttaagta gtgcatctat tatagatttt atgaagaatg
     3241 aaaaactaag gggaaaaact gttctttact caactcatta tatggaagaa gcagaaactt
     3301 tatgtgacaa gatttttatg attcacaatg ggaaaataat tgcatcagga acaccacaga
     3361 gtttaaaaga ggaatctgga gtaaataatt tgagagatgt attcataaaa cttgccagaa
     3421 aggaggacat ttaaatgaga agtaagattg taaaatacat atttaaaaaa gaaatgttag
     3481 acatattgag agataaaaag actttattta tgatgattgt tgtgccactt cttttatatc
     3541 ctttacttat gttattaatg attcaagtaa tgaatatgtc tgcaagtagt atgaatagta
     3601 aggacattaa tatagctttt aataataaac ctaataaggt gttagtatcc atgattgaag
     3661 atgataattt agaaaaagat actaaaaata cttcaaatga taaaggcaaa ataagagtgt
     3721 tagatgtaga taactataaa aagtcattag aagaaaataa aattgatgct tatataaaga
     3781 tggaagaaaa aaaatcatct ataaattatc aaatatatat aaattcttct caagaaaatt
     3841 cttctaatgc actaaaaaga attgaaactg ttttggataa atataaaaga tttaccatag
     3901 aaaaaacttt atctgaaaaa ggattagatg tacaagctac tttagaacca ataacatata
     3961 gcactgtaga tgttgcaaag acggaagaag tggcaggata ctttttaggt cagatacttc
     4021 catttatatt aataatagga gttttactag gttcaatata tccagcaata gatgttatgg
     4081 ctggagaaaa ggaaagaggt acattagaaa cattatttac actgccaata tcaaacttag
     4141 aactggttat gggaaaatat atggcagttt ctcttagtgc aatagtaaca gcaattttaa
     4201 acattttatc tatgggactg actatggcat ttattttagt tagtggaggt attagtagcc
     4261 aatttggctt tggaaacttt aattatggag acttagtctt accaattata actactttaa
     4321 tttgcatatg tcttttttca atggtagttt cagcaataag tatgtgtgta tgttcattag
     4381 caaaaagttt taaagatgct caaaactaca taacacctct tatgttaatt attatgatac
     4441 catcatatgt ttctatgata ccaaatatag tattagatag agtgacagct gtaatacctg
     4501 tagtaaatat atctttactt ataaaaagtg tattatcttt taaaagcgat ttaaatttaa
     4561 tagccttagt tttagcatca aatgtagcct ttgttatatt ggcaatcata ctactgtcta
     4621 agatgttcaa ttctgaggaa atactttttg gtaatagtaa gagtttttct ttcttagaga
     4681 aaagaagtaa tataaaaaaa gggtctatac caactgtaag tgatggtgtt attttatatg
     4741 cagtaggatt agttctattg atttatgttg gttctttagt tcaaattaaa tttggtatgg
     4801 caggtattat aatgacacaa ttcatgataa tttctttacc attattattt gcatactata
     4861 ttaaagctga ttttaaagag gtatttagct tgacagttcc taaattaaag catgtgtttg
     4921 ggagcattgt tctttggatt ggtggataca tacttattat gattataaca cagctaattt
     4981 tattcttatt tcctcaaaat atggaagttg ctgaaagttt aaataaggct ctttttatca
     5041 aagatagtgt tttactgaat ttactagcaa tagctttatt accagctata tgtgaagaaa
     5101 tgttttttag gggatttata ttttcttcat ttagtaaatc aaaagataaa aataagtcta
     5161 tcaaactcgc tataatatgt agtggggtac tatttggtat tatgcatatg gattttatta
     5221 gaataattcc aacatcaata ttaggtatta tatttgcata cagtgtgtat aaatctggtt
     5281 caatatttgt atcaatgtta ttgcattttt taaataatag tgtagcagtt gtgttaaatc
     5341 attatacaac tggaaatata accaacttat ataaatttgt tgaagttgat ttttcgaact
     5401 taaatgtgct taaatttgcc ttaattcttc taataagtct tatattaatt atgttaggat
     5461 taagagtttt agatagaaag tctttaagaa attaagtata aagttattat atagattaaa
     5521 atattaataa gcactaaagt atatggatat atcttg
//
LOCUS       DAMJWC010000132         5533 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMJWC010000132 DAMJWC010000000
VERSION     DAMJWC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.137"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="PC503_003557"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="PC503_003557"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(385..1569)
                     /locus_tag="PC503_003558"
     CDS             complement(385..1569)
                     /locus_tag="PC503_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2529507.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1942..4293
                     /locus_tag="PC503_003559"
     CDS             1942..4293
                     /locus_tag="PC503_003559"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF2529508.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4315..4854
                     /gene="nrdG"
                     /locus_tag="PC503_003560"
     CDS             4315..4854
                     /gene="nrdG"
                     /locus_tag="PC503_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF2529509.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2156 a          628 c          891 g         1858 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa gctctctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg taattttttt
      181 gttataataa atttagaatt taacttatat agtttaattt gataatttga tgaaaaaaat
      241 aaaagactta ctgattttta aatctatagg tcttttattt tttatctaac atttaaatta
      301 agttgttgaa tatatcttat attacttacc ttatatatta attaccatta atacattata
      361 tctaattact attcatctaa attattatgc cattatttta tatacaaatt cttttaattt
      421 atctaatcca gataagaaag tattttcact gcaagcatag gatatacgaa tatatttatc
      481 cataccaaat gctatgccag gaacaactgc aacattatat tcttctaaaa attgattaca
      541 aaattctata gaaaaactat ctttatattc aaatttctca gatactttag aaagatctat
      601 aaatatatag aatgcgccat ttggattcac atatcctaca ttatcaatag agtctagttt
      661 tgatttaatt aaatctcttc ttgatttata tgttttaacc atattgtcta tgtcaattga
      721 gcaatctttc aaggctccat aggctatgta ttgtgctgtt agacttgggt gagatataag
      781 atgtccttgt atagaactca ttgctttagc aatcgtttta ttagatgcag tatatcctaa
      841 tcttaatcca gtcattgcag ctgacttaga aaaaccattt atagttattg ttatatcttt
      901 agcttcttcg cttaatgatg caattgatgt aaattcacca gtgtagcata ttttttcata
      961 tatttcatct gctaaaatat atattttatt ttgtatgcat acatctacta tttctattaa
     1021 ttcatctttt gtataaacac taccagtagg atttgaagga ttgtttatta caagaatttt
     1081 tgttttatct gttatagatt tttcaagttc atcttttgtt aacttaaatc cattttcttt
     1141 tttagtatca ataaaaactg gaacagcatt aactaactta accatttcag gataactaac
     1201 ccaataaggc tttggtaata agacttcatc tccttcgtct gttaaagcta gtaaagtatt
     1261 tgttattgag ttttttgctc cacttgatac aactatttca tctattgaat agttacagtt
     1321 attttcttca ataagttttt tacagatttc ctctctaagt atttttaatc ctggaactaa
     1381 atcatattta gtgtaatctt tatttaaaga atcaatacca taagattttg cgttattagg
     1441 tacattaaaa tcgggttctc ctatactaag atttattact ttaactccat tactttccat
     1501 ttctttaact ttagaactaa tacctattgt gtaggatggt gttataaagt ttagtctttt
     1561 tgataacata aaatgcctcc ttttaaatta ttatttatat tatacgacaa atttaaagaa
     1621 tttacataag gaaatttgta gatatataca ttaatatata taatagccta cactttttgc
     1681 ctaaaattag tgtaaaaaaa agagaaaaaa attttaactt tcaaagttgt tagaaacgct
     1741 actgttcaaa atatccacat agtatttgca atgatttgcg caagtttgac tattatgtac
     1801 aaatttggta atcttaatat agcaattatt aagataatcc ctttaactta gttgaagggg
     1861 atttttttag acttaacata ctacatatag tggtatgggg attaataaaa tacaatatat
     1921 agtaacagga ggttttttta attggttgaa ttcgtaaaaa aaagagatgg aagagtaatt
     1981 ccatttaatg aagatagaat aacaagagct atatttttag cagcaacgaa tgttgcagaa
     2041 agagaaggaa tagtacctga ttataaatta tctgagcaat taactcaaga agtaataaag
     2101 tttttaaatc ataaatactc agaatcagtt ccaagtgttg aagatataca agattctgta
     2161 gttaaggttc ttatagaaac tggccatgca aaaactagtg aagaatatat aatatacaga
     2221 actgaaagaa gtagaataag aaattcaaaa acaagattga tgaaggcaat agaggaaatt
     2281 acctttgaag atgcagaaga tgctgatata aaaagagaaa atgcaaatat taatggtaat
     2341 acagcaatgg gaactatgtt acaatatgga agcactgtat ctaaagaatt ttgtaaaaca
     2401 catatattaa aaccagagca ttcttttgct catgataatg gagatataca catacatgat
     2461 atggattttt taaatatggg aacattaact tgttgtcaaa tagatgttaa aaaactattc
     2521 aatggtggat tttcaacagg acatggcttt ttaagagagc cacaagatat aataagttat
     2581 ggtgcattag ctgcaattgc tatacaaagc aatcaaaacg atcaacatgg aggtcaaagt
     2641 ataccatttt tcgattatgg attggctgaa ggtgtatata agacatttaa gaaattctac
     2701 ataggaaatt tagctaaagc attgaagtta tttaaaggaa ttgaaaataa tgatgtgata
     2761 aagaacatag tatataatac agagaaagaa acaaatcaaa aagttggtct taagagagat
     2821 gaattgtatc taaacttaga aaaagagaaa ttaatacaga cttttgatat agatgatgaa
     2881 cttgtaaata agatgcaaaa ctttgcattt gaagaatcgt atagagaaac tgataaaaaa
     2941 acatatcaat ctatggaagc atttatacac aatctaaata caatgcactc tagagcaggt
     3001 gcacaggtac cattttcaag tgtaaacttc ggaacagata cttctgaaga aggaagaatg
     3061 gtaactaaga atcttctatt atctcaagaa agaggtttag gtaatggaga gacaccaatt
     3121 tttccaattt taatatttaa ggtcaaagaa ggcataaatt taaatcctga agaccctaat
     3181 tatgatttat ttaaattatc atgcagagta tcagctaaaa gactattccc taattttagc
     3241 tttttagatg cgccttttaa tgcaaaatat tataaaaaag gtgaaccaga tacagaggct
     3301 acatatatgg gttgtagaac aagagtactt agtaatgtgt gtggttcaga aacagttagt
     3361 ggtagaggaa acatatcttt tactacagta aatttaccaa gattgggtat aaaacatggt
     3421 attataaata atgaaaaggc taatttagat ggtttctttg aagaattaga tgagaagata
     3481 aacttaatta tagaacaatt attggagcgc cttgaggtac aaggaaataa aaagatgaag
     3541 aattttccat tcttaatggg gcaaggtgta tggaaaggtt ctgatgattt aggaccagaa
     3601 gatacactaa aagaagtaat aaaacaagga acattgacaa ttggatttat aggtttagca
     3661 gagtgcctta ttgctcttat aggtaaacat catggagaaa gtaaagaagc tcaagaatta
     3721 ggattaaaaa tagtgtcaca tatgagacat aaaatggatg aagcaacgga caaatataaa
     3781 ttaaatttct ccttaatggg tactccagca gaaggtcttt caggtaggtt tactaaaata
     3841 gataaaaaag tttatggaga aattaaaggt atcacagata aagaatatta tactaattca
     3901 ttccatgtac cagtttatta caatataagt gcatatgata aaattgagat agaagctcca
     3961 taccatgaat tgactaatgc aggtcatata acatatgtag agttagatgg agatccatct
     4021 gataatttag aagcttttga aactgttata aaagctatga aagatttggg tataggatat
     4081 ggaagtataa atcatcctgt agatagagac ccaatatgcg gtttttcagg tgtaataaca
     4141 agtaatatat gccctgtatg tggaagaaat gaagatgaaa gtgacatcaa attcgaaaga
     4201 ataagaagaa taacaggata cttagttggt acagttgata gatttaataa tgctaaaaaa
     4261 gcagaagtaa gagatagagt aaaacataga tagttttatt tgggggaata agttatgaaa
     4321 ataagaatgt catctactat aagttatgac agcatagttg atggaccagg attaagaatg
     4381 gtaatatgga ctcaaggatg tattcataat tgtaaagagt gccataatcc tcagacacat
     4441 gatttatgtg gaggatttta tatggataca gaagaaatta taaataaagt caaatcattg
     4501 aaattacaaa aaggcattac gctatcagga ggagaaccat ttttacaacc agaaccatta
     4561 gaagaaatag caagagaagc taaaataaat gggttagatg tatggtcata tactggattt
     4621 acgtttgaac aactgttaga taaaaaaaat agagcgtatt ttaaaaattt aaatttacta
     4681 aagcaaattg atattttagt ggatggaaaa tttatagctg aaaaaaaaga tataagctta
     4741 aagtttagag ggtcatcaaa tcaaaggata attgatgttc aaaaaagttt gaaatataaa
     4801 aaagtgtttt tggttgagca atatatgaag gatgatttat ctatagcaga ataaaatata
     4861 aataaacagg attaaatata tgcatatatt taatcctgtt tattttcata taatatttca
     4921 agcttgtata atgtaacaat taaaccaaaa gactcattgt atatttgaaa ttaagttttt
     4981 tatagtttat aggtgtttta tgtggattac gaatgatata gtattgatac attatttaat
     5041 agattcttat gccaagaaac aattaattta tagaaattct taattgttac aatataaata
     5101 tctagataag ttataagata ctgataaata atttataaag tttattaatc taatattgtg
     5161 tgtgaatatt aagtggtcaa gtagtctaaa aaatgaaaaa gatttaaaaa agtgttttaa
     5221 ctaaacacat aagtgttaaa ttcatgtata agtataggtt agatacataa gaaataatta
     5281 tgtaatatct atctttgtaa aaaaatatta aattttgtaa tttgtggata aatatgttta
     5341 taatgtggat aatatttaat gtaataagtt aaagcaatat gaatcaactg tttataatgt
     5401 ggataatatt ataaatgtat gaataattgc agtatttaaa aacaaaaaaa gttaaaaaag
     5461 ttgttgactc taaaagaaaa agttggtata gtaatacttg tcctcaagaa aagggcaaac
     5521 aaataaagca taa
//
LOCUS       DAMJWC010000133         5412 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMJWC010000133 DAMJWC010000000
VERSION     DAMJWC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.138"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            139..975
                     /locus_tag="PC503_003561"
     CDS             139..975
                     /locus_tag="PC503_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2529510.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1328..2905
                     /locus_tag="PC503_003562"
     CDS             1328..2905
                     /locus_tag="PC503_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2529511.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSNFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2898..4082
                     /locus_tag="PC503_003563"
     CDS             2898..4082
                     /locus_tag="PC503_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2529512.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            4100..4699
                     /locus_tag="PC503_003564"
     CDS             4100..4699
                     /locus_tag="PC503_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2529513.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4723..5193
                     /locus_tag="PC503_003565"
     CDS             4723..5193
                     /locus_tag="PC503_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2529514.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         2030 a          564 c         1032 g         1786 t
ORIGIN      
        1 aaaaaatatt ttgttattgt agtattatag ggtaaattgc aaaatatata cgaaagtaaa
       61 attttaaata ttgacattaa attaaatata ctatactatg taagtgtgat gagagaattt
      121 ttttagaggg gatttatagt gaatataaaa aagatattta ataacaatgt agtagtaagc
      181 tccctagaag atggcacaga aataattgtc actggtgctg gagtaggatt taagaaaaaa
      241 gtaggcgatt tgatagatga aaatttgatt tctaagaaat attttgttca agacgatcaa
      301 agggacaaat acaatcaaat acttaataag acctctattg aatactttaa aatttcagaa
      361 gaaattatag aaaaggctaa tgaagtttta aatactcaag tgaatgattc aataatatta
      421 gccttaacta gtcacataga atttgctgtc caaagagaaa aacaaggtat aaaattacca
      481 aacttaatat tgaatgagac aaaacaactt tatagggaag aatttgaatt tggattatgg
      541 gcaattgatg aaattgaaaa aaggatagga ataaaattgc ctgaagatga agcaggatat
      601 attgctattc acataatcaa tggtttggaa aattctcaaa aagatgaagg tattaatata
      661 ctagagtttt caaaacaagt tattcagata attgaagaag tacatggatt taaattggat
      721 gtaaattcat taaattatac tagacttata actcacttaa agttttttgt tcaaaggatt
      781 ctccgaaaag aaacttacaa tgatagtgat attgaagata tgtataagtt agtgaataaa
      841 aattacaata aacctaaagt gtgtactgaa gaaattgcag cattggtatt agacagattt
      901 gaatataaga ttagtaaaga agaagaatta tatttaatga ttcacataaa taaaataaca
      961 aacagtggtt gttaggattg taactgataa agcaggcaaa acctaagtca ttgagcttaa
     1021 ctattagatt aagttttttg atttaggttt ttttattaga tacaatcaaa atacagacag
     1081 tgacttttag gattgtaact ggttaagcag gcaaaaccta aatcattgaa tttaactatt
     1141 aggttaagtt ttttgattta ggttttttta ttagatacaa tcaaatacag acagtggttg
     1201 ttaggattgt aactggttga gcaggcaaaa cctaaatcat taaacttaat tattaaatta
     1261 agttttttga tttaggtttt tctataaatt tgattatgtt tttagataaa aataggaggg
     1321 gaaaattatg aaaaaaaata agttaggttt atggaacttc ttccaaatgt taggaaaaac
     1381 gtttatgttc ccaatagcac tacttagtgt ttctgggatg atgctaggac ttggggcagg
     1441 ttttacagac cctaagatga ttgaaatggt tccattttta gggaatgaat atgttaactt
     1501 agttttaaac ttcatgttaa caataggatt atttgcattt aacaacttgg gagcattatt
     1561 tgcaatggca attccactag gattattaaa aaaagaaaaa gagtttggtg ctttttcagg
     1621 attagtagga tttatagcaa tgcatatagg tacaaatttt tatttaacaa gagctgattt
     1681 gttagtacca gcagaacaga tgtcaactaa tggtcaagct atgattatgg gtatacaaac
     1741 atataataca agtgttttag gtggtattgt agcaggatta attgtttatg caatatatga
     1801 taaagttagt aatttaaaga taccagaatc attaggattc tacagtggac caagattagt
     1861 tccaattgtt agtttaatag ttatgagtat agttggatta ttaataccta ttgtttggcc
     1921 accatttttc aatgcattcc aaagtttagg aagatggatt tcttcagcag gaccattagg
     1981 atatttttca tatgcagtgg cagaaagagt tacaattcca tttggactaa atcatcttgt
     2041 aacatctgta ttccgtttta caccaatagg tggaactgct gttattgatg gagaaacgta
     2101 ctttggtaca ttgaacatgt ttatggcata tgtagaaaat aatcagatta tacctcttga
     2161 tttagctggt aaaatggaac aaggtaaatt gatgattcaa tatggattag ctggtgctgc
     2221 attggctatc taccgtacag caaaaccaga aaatagaaag gcacttaaag gacttttaat
     2281 atcaggagtg ttgacagtta ttataggtgg tataagtgaa ccaatagagt ttctattctt
     2341 attcatatca ccagcattat ttgctttcca tacatttatg aatggtctag caaacatggt
     2401 acttccatac ttaggcgtgt tgatgggatt cacaggagat ttaattgcat ttataagttt
     2461 tggtgtgtta agaggaacag ctacaggatg gccaatagca gtattagtag cagttttata
     2521 ttttgcaata tactattttg tatttaagtg ggcaattatt aagtttaata taaagacccc
     2581 aggacgtgag gataaagaaa taaaagtatc tgaaggaaat ggttcaaatt tcaaaaattt
     2641 gtctacatat aaaggacaac aaatgatatc tgctttaggt ggtcaatcta atatattatc
     2701 actagataat tgtgtaacta gattacgttt aaaattacaa gatgtatcat taataaatga
     2761 ggatgcaatt aaagaggctg gtggtatagc agttgttaaa ttggatgagc atacaataca
     2821 agtaattata ggaacccaag tgtattcttt aagaaagcag atggataaag ctatggaagg
     2881 tcatttggag gcatgtaatg attaattttg ataaaaaagt agaccgattg ggtacatatt
     2941 gtacccagtg ggactatgta gaagatagat ttggtaagaa ggatttgctt ccttttacaa
     3001 tttcagatat ggatttagag tttccatttg aaataacaga ggtgttgcag gaaaggttaa
     3061 atcatagagt tttgggatac agtagatgga aacatgatga ttttagaaat tcagttacga
     3121 attggtatat taaaagattt aattgtagcg ttgatagtaa ctggatatat tatagtccaa
     3181 gtgtaatgta ttcaattagc aaacttattg agatgttaag taatgaagga gatggaatcc
     3241 ttataaatac tcctgcatac aatgcttttt atgatgtgat aataaataac aatcgtaata
     3301 ttataaagtc acatcttgta aataggaatg gattctattc aattgatttt aatgattttg
     3361 agaaaaagtg taaaaaatct aagatattta ttttatgtaa tcctcacaat ccaactggta
     3421 gagtatggag tgagttagaa cttgttaaga tgataggaat ttgtaagaat aatgatgtca
     3481 agataatatc agatgatata cacatggata ttgtatatga caatagaatg acacctatct
     3541 taaatgttgc aaaggactat ttagattctg tattcatttg tacatcagcg tctaaatctt
     3601 tcaatatacc agcattgact gggtcatatg tgattatacc aaatgaaggt attagaaata
     3661 aatttgaaaa tatcactaga taccgtgatt ttgtaaattc gccagcaatt ctagcaatat
     3721 tagccacaat ggtctgttat gatgactgcg aatattggtt agatgaacta ttaaaatacc
     3781 ttaaagagaa tcttaaatat acgattgatt atataaaaga taatttagaa ccattgaaat
     3841 tggtcatgcc agaaggctgt tactttgctt ggatagattt ttccgaactt aaaataagtg
     3901 gtgagaaatt ccaaaaatta ttgatggata ttggagaagt tgctattatg tcggggtctg
     3961 tatatggtga agaaggtgag ttttatttaa ggttaaatgt ggcatgttca agagaaaaac
     4021 ttgaagatgg tttaaatagg attaaaaaaa ctatggatta tattgaaaaa agaattttat
     4081 agtaggaagg gagatagtta tgggatattt aaaaacaatg gttgatgtta tgactactga
     4141 aatgaatgcc ataagatgtt taatagatga agcaggaata gaatatgaaa gtatagttag
     4201 tgaaattgca aattgtgaag gcaaagtaat ttttatgggt gtaggaaaat ctgcacatat
     4261 aggtaagaaa ttggcagcta catttgctag tactggtaca cctagctttt ttgtacatgc
     4321 aacagaggca gtgcatggag atttaggaat gattgaaagt aaggatatta caattttaat
     4381 atcaaatagt ggaaattcta tggaagtggt aaactgtata aaatatatta aagcaatagg
     4441 ttctaagaca attgcattta cttcaaacag aaattcagta ctggcaaaag agtgtgatta
     4501 tgctttaata tatcctgcaa aggatgaagc agaccattta aatctagcac caacaacatc
     4561 atctacaatt actttggttt taggagattc tattgcatgt gcattatcta agagtagtaa
     4621 ttttggttct tcagattttt ataagtacca tccaggagga agtttaggtg agaagttaaa
     4681 aacagctaac aatggataaa agcaaaaagg agagtagttt ttatgttcaa aatgtttaaa
     4741 aaaaaatcaa taaaatcacc catatcagga aaagtaatag agttatctaa aatacaagat
     4801 ggtgtatttt ctcaaaaaat tatgggagag ggtgtagcta tagattctac aggagacatt
     4861 gtatatgctc caatcaatgg aaagatagta gtagtagcag agactaaaca tgcatttgta
     4921 atagaattag aaaatggaat ggaacttctt attcatgttg gtttagatac tgtaaattta
     4981 aaaggcgaag gttttgaggc attggtgagt atgggagaac aagtgaagga aggaacacca
     5041 atgttgaaaa ttaaccgtcc tttgattgaa tcaaagggta tatcacttat tactccagtt
     5101 acaataacta atcattcaga gtacaatatg aatacatgta atgtaggcaa tagtgttgaa
     5161 ggtgggaaag atactgtaat tgagtttaaa taaagaacta aaatacaagg ttaatattta
     5221 taaataccta taaacttatg ttttataaga ttgattgtat agatttgttg tataaaaaag
     5281 aactctttaa ttataaatta aggagttctt ttttattttg taaatattgt ttagatttat
     5341 atagaaaaac acttagtaat aaatagaata aataagtatt tatatagcta aaaatctaaa
     5401 tagttttgtt ta
//
LOCUS       DAMJWC010000134         5357 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMJWC010000134 DAMJWC010000000
VERSION     DAMJWC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.139"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            215..1678
                     /locus_tag="PC503_003566"
     CDS             215..1678
                     /locus_tag="PC503_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2529515.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            1734..2870
                     /locus_tag="PC503_003567"
     CDS             1734..2870
                     /locus_tag="PC503_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2529516.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            3106..4221
                     /locus_tag="PC503_003568"
     CDS             3106..4221
                     /locus_tag="PC503_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF2529517.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            4373..5242
                     /locus_tag="PC503_003569"
     CDS             4373..5242
                     /locus_tag="PC503_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2529518.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSRRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT         2070 a          545 c         1002 g         1740 t
ORIGIN      
        1 aacacacgtc gttaaaaatt ttataaattt atgtttagat atgattaata ctcttgattt
       61 tagaaataaa tatttgtaga ttgtagatta aagataatat aaataaatag aaggtagatt
      121 ttttagatat attaatataa agattatata aaatattgaa atatagctgt ttaaattatt
      181 gtctataaat ataaaatgaa tggtggtgag ttaagtgacc gatttagtta acaccattaa
      241 tggaattgtt tggtcacccg tattagttgc aatgtgtttg tgtataggat tatatttttc
      301 attgaaatta aaattttttc aaataagaga tgtaaaagaa atgtttactc tcttgcttga
      361 gggagatagt tctcatgttg gtatatcatc atttcaaggt tttgctacat ctatggctgg
      421 aagaataggg actggaaata tagctggtgt agctgtagca atagcaatgg gaggtccagg
      481 agcattagta tggatgtgta taatggctac attaggttca gcaactgcat ttgtagaatc
      541 tactttagct caaatatata aagatgagca tgatgggcag tatagaggag gacctccata
      601 ttattttgaa aaaggtcttg ggtggaaaaa gtgttcagtt ttattttcaa tagttgcaat
      661 aataagttat acatttttta tgcctggtac acaatcaaac actttatatc tagcaatgaa
      721 tcaagcattt ggattttcaa aaatgacaat agcagtagca tcttctattg cattagcgat
      781 aataattttt ggaggaatta aaaggattgg tttatttgct gaaaaagtag tacctataat
      841 gggtggagca taccttatta tgacattagt aataattata acaaatatta gtttagttcc
      901 agaggctatt gtaacaatgt ttaaatctgc atttggattt ggttcagttt ttggaggaat
      961 gctaggttca gcaatatctt ggggagtaaa aagaggtata tactcaaatg aagcaggaga
     1021 aggttctggg acttatggtg cggcagcagc agaagtaagt catccagcca aacaaggatt
     1081 agttcaagca ttttctgttt atgtagacac attattaata tgtatggcta caggtattat
     1141 gattgtaata acaggaatgt ataatgttac aggtgtttgc acagcactac caggtgtaga
     1201 accgggacca caatatgtac agagtgcaat aaatacatta catccacaat taggtgatat
     1261 ttttatagca atagttttat tattatttac atttacaact ttattagcct tctcatatat
     1321 gatggagact aatgtatctt acttagtaac tagaattaaa gcagaaaaac atgaaaagta
     1381 cataattaat gtctgtagat ttatgcttat agcatgtgca gcaatgtgtt gttttataga
     1441 accacttaca agctgggcat taggtgatat atgtataggt gtattaacat atataaattt
     1501 aattgccatc tttacactaa aaaaaccagc tataaaggca tattatgatt atataagaca
     1561 gaagaagatg ggaataaaaa ggagtgatag aacttttaac cctatagagt tagatataag
     1621 aaatgctgag ttttgggaaa atagatactt aaaagaggat aagcatgagt taaattaaag
     1681 ttataataaa atataaaaat tactaaataa atttagtggg aggtaagatt ggtatgaaag
     1741 aaagaataat acaagtggct gattcaaaga aagaaaaaat tctagggcta tgtcaatctt
     1801 tatatgatga accagaaatt gctttgcaag aatataaatc tgctaaaaaa atatcagaat
     1861 ttctaagaga agagggtttt gatgttgagg aaaacttggc aggtatggct acagctttta
     1921 aagcaaccaa gaaaaatgga gatggtccta aaatagcatt tatagcagaa tatgatgctc
     1981 ttccaggcaa tggacatgca tgtggacatc atttaattgc atctatggga gttggagctg
     2041 gaatagctct ttcaagtata ctggatactt acaagggaga agtaagtata attggaacac
     2101 ctgctgaaga aactggagat ggaaagcctt acttgataga acatggtgta tttgatggct
     2161 atgatgcagc aatgatgata catccaaatt caaaaacttg tgtaacacct gaaattatag
     2221 caataggagg tctagatttc atatttactg gaaaagcatc tcatgcagga gctaagccat
     2281 ataacggaat aaatgcttta gatgcagtag tactactata taataatata aatgcactaa
     2341 gacaacaatt agtagatgga acgagaatac atggtattat attagaagca ggaactgctg
     2401 caaatgtaat acctgatatg ggaaaagtaa gattagagat aagggcaaaa gaacaaaatt
     2461 actttgatga agtagtagaa aaagtgaaaa attgtgctag aggtgctgca atagccactg
     2521 gatgtgaact tgaattttat cactttgaac caacttgcca aggattaaat gaaaataaag
     2581 ttttggtaga catatttaca aagattatgg aggaatttgg aatatatgaa gatgaacaag
     2641 taatgttagg ttcaacagat atgggaaatt taagtcaaat aatgccatgt atacatcctt
     2701 tgatgaagtt ttctgaaaat ggagaagaac tacatacaaa agaatttttg gaggcttcta
     2761 taaattcata tgcaaaagat agagtaattg atggtataaa aatattagct ttaacaggat
     2821 ttaatttatt tgaaaatcca gaattattga aaaaaatgaa ggaagagtag aacttagact
     2881 atttttaatt atactcttta aaataagaag agtgtctcaa aatgaacttt ttagtttatg
     2941 agacactctt ttttgtatga aattaaatat atttttatta ttttaaacat gaaaaagagg
     3001 cttatctgtt tttatatgac cttttttaac ttgtagcaca aaatatcatg aatgattaca
     3061 attcgaatga taaaatcgat tataagatat ataggagggg tacatatgga aactttagaa
     3121 gtaagaaata ttgaattgag tggtacaaat tatgagatag gatacagact aggagaattg
     3181 gttgctaata tgccagagat aatagaaggt cagattaata aatctaatct ggtaagcaaa
     3241 aaagaagaaa aagagatgat agagttgttt gataaatatt gtccaggtct taatgaagaa
     3301 ttgcaaggtt ttgctgatgc aattcaagtg aattgtaatc aaattttata ttatactatg
     3361 acttatctta aaccaggttg tagtcaagtt gcattagcac cagaattaac tgaaaatggg
     3421 catgtactat ttgcacgtaa tttcgatttc tcacacaata tggaggattt tgttttatgt
     3481 aaaactaagg taaatggaaa atatgcacat ataggtacta ccattatgca atttggaaga
     3541 ggtgaaggta tgaatgaatg tggcttaggt gtaagtcagt catcatgtgg tattcctgta
     3601 ggcaattcag atggtttaag aaaaccagca attgtaggtt tacagttttg ggctgttatt
     3661 agatatttgt tagaaaattg caaagatgta gatgaagcat tagaatattt aaaagatatg
     3721 ccaattgcat acaatattaa tttattgctt gcagataagt ctggaaacat tgcacttgtg
     3781 gagactttag atgggaaaaa agaagtaaat ataatcaaca gtttagaaag taaaagagaa
     3841 tattttttac actctactaa tcatacacat attgataaac ttcataaatt agatccacaa
     3901 tcaatgaaaa attctattca tagatataaa ttaattaaag aatatataaa taagtctaaa
     3961 aaaattggag agaaagagtt aatgaattta ttgtcttcaa aatatccaaa tggcttatct
     4021 tgtaattact ataatgattt ttttggaact ttaaaaagta tagttatgga tttaaatata
     4081 ggaaagttta atattttatg gggtggacta gagaataaat gggagagcta ctatttaaaa
     4141 aatgacatta aatctataac acagaggata aacataaata ttgaaaaagc accatctgac
     4201 ttttttgatt tcattgaata aaaaatgtat ttaattattc taaataatta ggacatataa
     4261 atcaactaaa agtttttatt tatcgtattg aattagttat aatattttag tatagtaaaa
     4321 aatagtgcta ttttacatat ttaaagagtt taagtagaag agaggtgcca tattggatta
     4381 cttaaagtat tttgaaaaag ctgtaatgta tattgagaat aatttacatg aaaatataac
     4441 tgtaaatgat gtggcaaaag aaactggata ttcttattat catttaacac gcttatttaa
     4501 gtctatgttt ggtgaaagtg taggaagtta tataaaaaaa agacgattag taagtagtac
     4561 aaaagaactt ttatatagtg ataaaaaagt gatagatata gctattggta gtggatttga
     4621 atcttcagaa gcatttagca gagcatttaa atctatatac aaggttagcc ctatagaata
     4681 tagaaaaaat agaattgatg tatttgttgg taaaaagaaa aaattagagt tagattttat
     4741 gagacatctt gttggaaata taacgattaa accagttata aaagaaatag aaaaaataaa
     4801 ggtaataggt ataaaggata aagtaatttt agaaaataat tcattacctg acttgtggga
     4861 gaaattcaga aaagtacatc atattgtccc aaatactttg ccatcaagga gagtttttgg
     4921 aatctgtgaa gcaatctctg aaatacacct agttagtgaa agtatggagt ttaatgagat
     4981 aataggactt gaagttaata gttatgatgt gattccaaat tcatttgttt caaaaactat
     5041 taaggaagga aagtatgcta tatttactca tactggtagc ttagataatt tagacaaaac
     5101 ttatgaatat atatggggta cttggttttt aagttcaaaa gaagaacttg atataagaga
     5161 tgattttgaa gtatatgatg aacgattttt aggtcctagt aatgtgaact cacaaattga
     5221 tatttatata cctataaaat aatctataag aaaactaaaa gataatttga ttaagaaata
     5281 gatgttcgta aaagagcatc tattttttat ttttataaga tttagataat tttaataata
     5341 aaagaaataa aaataag
//
LOCUS       DAMJWC010000135         5187 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMJWC010000135 DAMJWC010000000
VERSION     DAMJWC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5187
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.140"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(627..2762)
                     /gene="rnr"
                     /locus_tag="PC503_003570"
     CDS             complement(627..2762)
                     /gene="rnr"
                     /locus_tag="PC503_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF2529519.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3355..3969
                     /locus_tag="PC503_003571"
     CDS             3355..3969
                     /locus_tag="PC503_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2529520.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3987..4349
                     /locus_tag="PC503_003572"
     CDS             3987..4349
                     /locus_tag="PC503_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529521.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4455..4952
                     /locus_tag="PC503_003573"
     CDS             4455..4952
                     /locus_tag="PC503_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2529522.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1694 a          770 c          623 g         2100 t
ORIGIN      
        1 gaaaagttat cttaaataaa aaataagtgt atcttaaatt ttaaatgata cacttatttt
       61 tatattgaaa ttatattttt taatatctat tcttaattag gtatttttaa attatctgtt
      121 tacattaaat atttcttaat tacttatctt tcagctagct ttttctatta aatgtttctc
      181 aattacttat ttttcaatta gccacttata ttaagcattt cttaattact tatttttcaa
      241 ttagccactt atattaaaca tttcttaatt atttattttt cagttggctt tttctattaa
      301 atgtttctta attacttatc tttcagttag ctctttctat taaacatttc ttaattattt
      361 atttttcagt tggctttttc tattaaatgt ttcttaatta cttatctttc agttagctct
      421 ttctattaaa catttctcaa ttacttattt ttcaattagc tactttcatt aaatatttct
      481 taattattta tctttcagtt aactatttcc attagatatt tctcaattac ctatttttat
      541 catttatttt atagagtatt gtgcactata tatttataca tatcataaat actacaactt
      601 gttatctctt attttagctg ttttatctac tcctctattt tttcaactat ctcaaagtca
      661 atttctttaa aatctacatt aacactttca acctttatct taacaaggtc tcctatctta
      721 tatgacttct tagttctttc tcctaaaaca ctataagaac tctcatcata aatatagtaa
      781 tcatcattca tatttgcaag tcttatcaat ccttctatgg tattatccaa ctcaacaaat
      841 attccaaatg aagttacgct agatacaaca ccctcaaatt cttgaccaac tttatccttc
      901 atataaagag ccttatagaa atcatgtaca tctctttcag ctaactctgc ctttctttct
      961 ttctcggatg attgaacaga tgcataatcc actatagtag taagctgttc ttgtcttttt
     1021 ccacttattt tattatttaa agattctttt attattctat gaatttgaag gtcaggatat
     1081 cttcttattg gtgaagtaaa gtgacagtag aatttagctg ctaatccaaa atgtccacta
     1141 cattctggtg agtacttagc ttgttttaaa gaacgaagca ttatagtact gatagctcct
     1201 tcttcttttt tgccctttat tttctctatt ataccttgta atgcttttgg atgtacttcc
     1261 tctttatcac cttttattat atatccaaat gtagatataa acttactcaa ttcttccatt
     1321 ttttccaaag atggtgtctc atgtattcta tacacaaacg gtattcccat ccagtaaaaa
     1381 tgttcggcaa ttgtctcatt acttataagc ataaattctt ctattatctt attagatatt
     1441 cttctttcat atggctttat atctacaact tcgccttttc catttagaat tatctttgcc
     1501 tctgggaaat tgaagtctat agctcctctt ttttcccttc ttgacataag aatcctagct
     1561 aaaatttcag catttttaaa atcttcaaca acatgttcaa aagtcttttt aagtttttca
     1621 tcatcctttt ctaatatatc agatacttct gtataagtca ttctagcttt tgaatttatt
     1681 acagattcac atatttcatg tttaaccaca tttcctttat ggtctatttc cataaatata
     1741 gaaagagtta atttatcttc aaatggattt aagctacata ctccatttga aagagttttt
     1801 ggcaacattg gaattacttt atctactaaa taaactgatg tagctctttt taaggcttcc
     1861 ttgtcaagtt tatttttctc tcttacataa tgtgtaacat cagctatgtg aactcctagt
     1921 ttgaagtttc cattaggtaa tacttctatt gatatggcat catctaagtc ttttgcgtca
     1981 tctccatcta tagtaaatat gtttaaatct cttaaatctc ttcttctttt tatctcttct
     2041 tgaggaatct caacagctac agcttctgct tcttgcaata ctttctttgg aaattcttct
     2101 ggaagaccat gttctcttat tatagaatct atttctacgc ctctttcacc tttttgacct
     2161 agtatctcta taattttgcc ttctggtttt ctatcctctt gtggccatac tgtaatttca
     2221 catactacct tatcattatc tactgctcca ctaaaatgtt ttttaggtat atatatatct
     2281 ttagtaaatt tcttgttgtc tggtgttaca aatccaaaag ttttacttga ttggaaagta
     2341 cctactattc tagttatttc tctctttatt acttttacta ttcttccttc tgctctcttt
     2401 tcttcagttg caggtactac tatttctgcc ataactctat cattatgcat agcaccattt
     2461 atattgtcac ttgagataaa taaatcctgt gtatattcaa catcagattc tacaaatcca
     2521 aaaccctttt tgtgtgatac aaattttcca acaaagtatc ccatttgatt gggagatact
     2581 atttttcctt ttttagtaaa gcagatataa ccatcttctt ctaattcatt taaaaaatta
     2641 taaaacattg gcatttctga tgaatgtata tcaaatattt ctgctaattc ttcttttttt
     2701 agaggattat atgcactttc atttattaat cctagcaaac tttctttaag tcctggtatc
     2761 atttttccct cctgttttac ttttcattat attattattt atattgtctt ttatatttct
     2821 tcagacaaaa cattttttaa ttatcacata attttctata ttttcttatt attataagtt
     2881 aaaattactt atttatattt ttgatttaat gtaagctttg tcatactaac ttcaaacaaa
     2941 ttatgatgtt ttataaatta tttgtaaata tcattataat tacttaagtt attctttatc
     3001 ataattgctt aaattactct ttatcaccta attatacacc atcaaatagg attggtaaaa
     3061 tattcatctc atataagtat tactatataa taatttattc tattagtata ctcaaatcat
     3121 gtaaaattta tataactcaa ttaatttttt aaatacaact ttataatata aaacttataa
     3181 taaaagtaaa tttatatgtt aaatgaggtt gattttttat tattttttat ttatgctagt
     3241 actaaagact tgcaaacgtt ttttgacaag tctttatttt gtctaaatta aacaaacttt
     3301 tttacaaata aatacataaa atttaaacta atctatttat tggaggagat aaaattggaa
     3361 gaagtaattg caaaaattat tactatagaa aatggattca aagaaattga aaacattgct
     3421 aaaaaaattg taaaaaataa tgactcaaaa aagtgttatt atctatcaat ctacttatat
     3481 aggtcagaat attatcaagt aagagaattg gctgtgttta tacttggttt tatatcagta
     3541 actatttctg aagctttgtt atttttaaaa gataatgtga gtaaagatga aaactggaga
     3601 gtacaagaaa tactagctaa atcatttgat tattattgca gtgaagtagg atatgaaaag
     3661 gctcttcctg ttataaaaga atggcttaat tctgatagtc caaacataaa aagggctgtg
     3721 acagaaggtc ttcgaatttg gactagtaga gactatttta aatctaatcc tgacgttgct
     3781 atatcactac tttctagttt aaaagaagat gatagtgaat acttgagaaa gtctgtaggt
     3841 aatgctctta gagatataag taaaaaatat ccagatttag taaaaaaaga attagattca
     3901 tgggatatat caaataaaaa agttgagttt gtatataagc ttgcttcaaa atgtatcttg
     3961 gcaaagtaaa atggaggtga acttatttga aacttcgtga tgagtatact tgcccattag
     4021 aactaacaca tgatatgata aaaggcaaat ggaaatctat tatattatgg agattacgca
     4081 taggaccaac ttccttatca aaacttgaaa aggaaatcaa tggtattaat caaaagatgt
     4141 tacttgaaca acttaaagaa ttaattgaat ttggtcttgt agataaaaag acatatgaag
     4201 gttacccact taaagttgaa tactcactta cacctattcg agggaaacaa atattggatg
     4261 ctttggctat aatgcaagat ataggaatta gctttatgtt ggataatggt atggaagata
     4321 ttcttaagga aaaaggtgtt ttaaaataaa tagataccca caaaaaagta agtaatttac
     4381 cattattttc aactggtata taattaaatt atagatatat tctattaatt tattataata
     4441 ggaggtaaat tattatgaaa gtaactagta caggtatagt aaatggtgtt atagaagata
     4501 aatacggtaa aagaggaact cagttcaatg aaggtggtat gcctacatat tcactacctc
     4561 taaagtttga agatgctcca aagaatacag tatcctttgc tgtattttta gaagataaag
     4621 actctgttcc tgtatgtggg tttgcatgga tacattggtt agctgtaaat ataacaaaag
     4681 atgagttaaa tgaaaatgaa agtgtaacag ctactgattt tgtacaaggg actactagtt
     4741 ggcatggcaa actaggaggt cttgacagat tagaggccag tgtatatggt ggaatggctc
     4801 ctccagacag acctcatgtc tatgaaatac atgtatttgc acttgatact atccttgacc
     4861 ttgaaaaagg attctatatg aatgaatttt tcaaagctat tgaagggcat gttttagata
     4921 catttacact aaaaggaagt tattctaatt aattaggttg actatagcta atcattaatt
     4981 aaatgctaca tttaattgat gattagctta attgttatta gaatattttc tgcactttat
     5041 cttaatatat attttagttg actggtattt taatttctat tagattatta tcaatttata
     5101 taaattgatt ttagcttaaa acttacttat ctatttcagt ttctattaga attattatta
     5161 gactcattaa aataaaagca ctaatat
//
LOCUS       DAMJWC010000136         5004 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMJWC010000136 DAMJWC010000000
VERSION     DAMJWC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5004
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.141"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            30..1913
                     /locus_tag="PC503_003574"
     CDS             30..1913
                     /locus_tag="PC503_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF2529523.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2137..2817
                     /gene="pgmB"
                     /locus_tag="PC503_003575"
     CDS             2137..2817
                     /gene="pgmB"
                     /locus_tag="PC503_003575"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2529524.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2814..>5004
                     /locus_tag="PC503_003576"
     CDS             2814..>5004
                     /locus_tag="PC503_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2529525.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSD"
BASE COUNT         2060 a          454 c          953 g         1537 t
ORIGIN      
        1 aaattattat aaaggaggga aattttaaaa tgtctaataa aaataaagaa aatataactt
       61 taagtaatca aatcaaagga acaattcaaa atagtttaac aaaagaagct atattacata
      121 taccaatgag caattatgcc tatggttatg atagagaaac actacatata agacttagaa
      181 ctaaaaaaaa tgaagcgaaa agagtaattt tacgaatagg agaccaatat gtgtgggata
      241 aaggaggtgc aggaggagga aatttaaatg catctggagt tggttggtct ggtggaacaa
      301 atatagtaat gagtaaagaa gtagaaactg aattatttga ctattggata gctaagtgta
      361 agcctttaaa taaacgctca cgatatggct ttataataga aggtcaagag gaaaaacttt
      421 tatttacaga aaaaagaata atagagttgg gaaatgaaaa tgatgaaaag gaattatgtg
      481 aaataggtaa tttttttgga tatccatatt taaattatat agatatacct aaagtgccaa
      541 attgggtgaa agatactgtt tggtatcaga tatttccaga tagatttgca aatggtgacc
      601 cgtctataaa cccagaagga gtagataaat ggggagctat tccaaccaga gataatttta
      661 caggtggaga tttacaaggt gtgatagaac acttagatta tttgagtgat ttgggaataa
      721 acggaattta cttttgccct attacaattg gaaaaaccaa tcatagatat gatacggtag
      781 attatatgga ggtagaccct acattaggag ataaagagac tttaaaaaaa ctaatagaag
      841 aagcgcataa gagaaatata aaaataatgt tggatgctgt ttttaatcat ataggatatt
      901 attctaaaca gtggcaagat gtagttcaaa ataaggaaaa ttctcgatat aaaaactggt
      961 tttatataaa agatatgagt aaaattgata ctccaataga acaaatagat gaaaaaaata
     1021 taccttatga aacctttggg tgtgaaaaat atatgcctaa acttaataca gaaaattcag
     1081 aagtaataaa atatttattg gatgtaggca agtactggat acaggaattt gatatagatg
     1141 cgtggagatt agatgtttca aatgaagtag accatgtttt ttggagaaag tttagagaag
     1201 aagtcaaaaa agtaaaacca gacatttata tattgggaga aatttggcat ggtagtttac
     1261 catggttaat gggtgaccaa tttgattcag ttatgaatta cttgatgtca gaagccatga
     1321 aaaaattctt ttgtacagat gagataaacg ccgaagaatt taagtatatg ataaatgatg
     1381 taatggtaag ttatccaata caagttagtg aagttatttt taatttactt ggaagtcacg
     1441 atactacaag aatattgact tatgctaatg gaaatattga tagatttaaa cttgcatata
     1501 tgtttatgtt tgtacaaaca ggatgtcctt gtatatacta tggtgatgaa atcggaatgg
     1561 aaggagaatt aagttcaata tctgaaggtc aaagaaaatg tatggaatgg aatgaagaaa
     1621 aatggaataa ggatatattt gattttatga agaagattat tagacttcgt aaagaaaata
     1681 aagaacttag gtctatatca aatgaatggg tgttagcaga taaggaaaat ggaacgatta
     1741 tattgaaaaa agaatctatt tctataataa taaataattc atctaaaaat ataattttga
     1801 cgttaccaga ttatttagca aataaaaaag taaaagattt atatgaagaa gaaatagttg
     1861 atttaaaaga agaactaatg ttagagaaat acaagttcat tattttaaaa taatacaaaa
     1921 aagtatttat tttagatttc atgttaaatt attatacagt ttaaacaagt ctttataaac
     1981 gataaaaaat atggtctaca agtgagtgaa ttgaaagtag attttaaatt aaagactgag
     2041 ttagagtaga taattttata aataatatct taaatacaag atagaaaata aattgattat
     2101 tagtctaaaa atttcttgta gaaagaggaa ataagaatga ttgaagcatt tatatttgat
     2161 ttagatggtg taattacaga tactgcatat tatcactata tggcttggag aaaactagct
     2221 cataaagttg ggatagatat agacacaaaa tttaatgaat ctttaaaagg cataagtaga
     2281 atggagtcat tggacaggat attagaattt ggaaataaga aatattcatt ttcagaagaa
     2341 gaaaaagtga gaatggctga agaaaaaaat aattactatg tatcattgat agatgagata
     2401 acttcaaatg atattttgcc aggcatagaa agcttgttaa ttgatgtaaa atctaataat
     2461 ataaagatag gtctatcttc tgcaagtaag aatgcaataa atgtattaaa tcatttgggt
     2521 ataagtgaca aatttgattt tatagctgat gcaggaaaat gtaaaaacaa taaaccacat
     2581 ccagagatat ttcttatgtc agcgaaaggg cttaatgtaa atccacaaaa ttgcataggg
     2641 atagaggatg caagtgcagg tatagacgct ataaactcag ctaatatgtt ttctgttggt
     2701 gttggaaatt atgaaaactt aaaaaaagca aatttagttg tagattcaac aaatcaatta
     2761 aagtttgaat atatacaaga aaagtataat gagtatatag ttaggagaat tatatgaaat
     2821 gtttatttag taatgtagat gagtggaaga ttatacaaga taagattgaa atcaaagaaa
     2881 atagattagc agagtccata atgagtatag gcaatggata tatgggtatg agaggaaact
     2941 atgaggaaaa ttatagtgga gatacacaca aggggtctta tatagctgga gtatggtttc
     3001 cagataaaac tcgtgttggt tggtggaaaa atgggtatcc agaatacttt ggtaaaattc
     3061 ctaattcagt caactatata ggtgtaagaa ttttcataga tgatgtagaa ttagatttag
     3121 caaaatgtaa agtagaagat tttcatagag aattagatat gaaaaatggt attttaaatc
     3181 gtaggtttat tgtaaatata aatgataaaa aatttgaagt tagggttact aggtttttaa
     3241 gtatatctgt taaggaactt gcagtaatta aatacagtat aaaatcatta aattctaata
     3301 ctaaaataaa atttgtacca tatttagatt caaatataaa aaatgaagat tcaaactatg
     3361 aggaaaagtt ttggaatgga atttcttcaa gttctttaga atataaaggg agtattcttt
     3421 ctcgaacaaa ggagaatgca tttaatacac cagtattcac tgtgggttca atgatgtata
     3481 ttaagacaaa tggtgatgta gaagctgtat ctcatgagag tgattataat tactgtgaaa
     3541 attcgataac aatggatgtt ttaaaaaatg aggttgcaag tatagaaaaa tatgtatcta
     3601 taacctcaac tagagattat aaggaaagtg agctattaag aaaatgtgaa gacattttaa
     3661 atagagaact atctaaaagt tatgatgata tattaaatga acatataaag ttatggaata
     3721 aaagatggga aagtgcagat gtaaaaataa atggagataa aagtagccaa caaggtataa
     3781 gatataattt attccaacta ttttcaacat attatggaga agattcgcga ttaaatatag
     3841 gtccaaaagg atttactggt gaaaagtatg gaggagctac ttattgggat acagaagcgt
     3901 tttgtgttcc agtatatcta ggtgtagcag ataaggaggt aactagaaat cttttagaat
     3961 ataggtacaa tcagttagaa caggcaaagg ataatgcaaa aaaactaggt cttaaaggtg
     4021 ctttatatcc aatggtaaca tttgatggag tagaatgtca taatgaatgg gagataacat
     4081 ttgaggaaat ccaccgaaat ggaagtatag tatatgcaat atataactat acaaattata
     4141 caggtgacta taaatatata aaagaaaaag gaatagatgt aataatagaa atagctagat
     4201 tttgggcaag tagagttcat ttgtctacaa aaaaagattt gtatatgata catggagtaa
     4261 caggtccaaa cgagtatgaa aacaatatca ataataattg gtatactaat tatatagcta
     4321 aatggtgttt agattatgct gtagaaaata tcttacgatt agagaaagag tgtaatgaat
     4381 gtattgacag aaataatgtg actagggaag aagttgagtt ttggaaaata atatcaaata
     4441 aaatgtatct gctgtatgat gaggaactac aaataataat tcaaaatgat aattttttag
     4501 ataaagaatt tgtagaagta aaggatttac caaaagaaaa ttttcctctt aatcaaaatt
     4561 ggtcttggga taagattctt aggtcgtgtt ttataaaaca agcagatgta ttacagggaa
     4621 tttactattt tggaaataga tttactaaag aagaaaaaaa gagaaatttt gacttctatg
     4681 aaaaatatac tgtacatgaa tcttctttat cttctagtat ttattctatt attgcctcag
     4741 aaatagataa cctagaaaag gcttatgaat tatattcaag aacagctagg cttgatttag
     4801 ataattacaa taatgataca aatgatggac tgcacataac ttcaatgtct ggttcatggc
     4861 tttccattgt acatggattt gcaggcatga gaacatggaa tgaaactcta tcttttgacc
     4921 ctaagttgcc aaaagagtgg aaaaattatt ctttcaatat aaattataga gataatatta
     4981 ttaatgtaga tgtatgtagt gatt
//
LOCUS       DAMJWC010000137         4865 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMJWC010000137 DAMJWC010000000
VERSION     DAMJWC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.142"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            863..1525
                     /locus_tag="PC503_003577"
     CDS             863..1525
                     /locus_tag="PC503_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529526.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1534..4041
                     /locus_tag="PC503_003578"
     CDS             1534..4041
                     /locus_tag="PC503_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529527.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4372..4716
                     /locus_tag="PC503_003579"
     CDS             4372..4716
                     /locus_tag="PC503_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529528.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
BASE COUNT         2152 a          426 c          706 g         1581 t
ORIGIN      
        1 ttaaaaatat aatgaaagtt tagttttaat tcatttattt aataaacatt tcaagtaaaa
       61 taatgtttaa atcagaaata taaataaata ttattataat cgttattaaa gaccaaaaat
      121 cccaccttag aagtttgtat catatgaaac ctttatagat tatgaaagca ataatatagt
      181 gtatgatata taaaataagt tataaaagta tttttttaga tattcaaaaa gacattgtaa
      241 gttatattaa taatatgggt atcaacgaat tttggatata atgagttttt caacttaaag
      301 ttatgtaata atgaatgtaa agaatattta atgaaatcat tttgttggtt atgtctagct
      361 gaatacaata atcttttaga taaagatttt atatttgaag ataggtgtga aaaaattaag
      421 aagatattaa catcagcagt ttagaggcaa agcatgtaaa gtaaagtctg ggtaactaaa
      481 agtagtaatt tagattgtaa ctattgttat aaatatgaaa atgaggaaac aggaaatata
      541 agttaggatg tagaaaatag gttactaaat aaaaagctta attatataat caaagaaata
      601 ggtatatact gtacaatttc atggtgaaga acttttccta aataaaaagg ttggtaaaag
      661 agatataaga aataaaattc aattataaga tatggtatga taactaaagg cactatatgg
      721 agtgaatagg cggaagaatt ttttgaaaat tataaaaata gtttctgttg ctacatatca
      781 ataagtatag atagagattg caaaatccat agcaaaaatc gaatttataa gtgtaaataa
      841 catgtaagac aaggagtaaa ttatgagtat tttagagata aaaaacctaa ataaaatata
      901 tggtaaatcg gaaacagagg tgaaagcgtt aagtcaaata aatctaaaaa taaatagtgg
      961 agaatttgtt gtgatagtag gtaaaagtgg aagtgggaaa agtactttac tacacataat
     1021 ggcaggactt gaaactccaa caaatggtga tgtgattatt gataatataa atatatcatc
     1081 tcttgatgaa aagaaaagat ctgcattacg taaagaaaag ttgggattaa tatttcaatc
     1141 atataatttg attccagttt taactgttga agaaaatata aaactaccaa ctataaatat
     1201 aaaaaataaa gatgaagctt atattaatga attgatggag ttactaggaa taaaagatag
     1261 aagaatgtat ttgccaaatc aattatcagg tgggcaacaa caaagagtag caatagcaag
     1321 ggctcttgta aataaaccat caattgtatt tgctgatgaa cctactggaa atttagacac
     1381 aaagacagag tcagatgtat taagtttatt aaaagaatct caaaaaaaat ataatcagac
     1441 aataataatg ataacacata atatagatat aacaaaatat gctgatagag ttatagaaat
     1501 agaagatgga tttataagag agtaggtaga tttatgaaac ttaattatat tgtaaaaaaa
     1561 tatataatgg gaaataagaa aaatacatta ttaataattg taagtattgt aatttcaaca
     1621 gcgttgtttt taattatgaa tataataagt gaagatgcga caaacttaat gataaatcaa
     1681 gctaaaaatg aatttacatt aaaacatgca caatatatca atccaaaaga cgaagaaata
     1741 aaatatatag aaaataacac aagtatagat aaagttggaa aatcaatgct tttaggaatt
     1801 agtgatattg gtaaaggtca aacactacaa attctatctc aggataaagt tgctgaagaa
     1861 ctaaatgata tttacacact agaaaaaggt aaattaccag tagctgaaaa tgaaatcgct
     1921 atagattcat ggtatattaa acaaaaaaag ataaaaaacc ctataggaaa aaggataaca
     1981 ttagattata gaagacaagg gatagatcaa gaagatttat atactgggga aaaagaattt
     2041 aaaataactg gtatcttaaa tagtaatcct attttaaaag ctcaaggaac atcaattggc
     2101 cttataagta acgattgtgc tatcaagaat attcctacta aaaataaata tgatcaagtt
     2161 atgtttactt ttaaaaagga aaaaaatata cagagacaat cacaaaaact tattaaaaat
     2221 ggaaatttga atgagaataa catttatttt aataatgaat tattaatagc tatatctgat
     2281 agtatgaatt taaaaatacc ttatataata gttaatatag tactagcact agcaactata
     2341 ttattaattt ataatatttt ttatatatta gtatcaaata gaataaagga ttttgggata
     2401 tttagggctt tagggtttaa tccaaatgat atttttaaaa taatgatttt agaagtatct
     2461 atatactcta ttataagtat ttctataggt ctaattttag gtgggataat agctagttta
     2521 tcaagggagt atgttatagg agtaatatac aatgtcaact atataaattc tataaaaaac
     2581 cagaactata taaacacata cataatttct atattattaa gtttaggaac tataataata
     2641 tcagtttcaa aacctcttat gttatcagtt aaaactgatc caatgatttg tataagaaga
     2701 aataatgaaa aagtggatat aaaacaaaat tcctttataa ataaatttat gataaaactt
     2761 ttcaaagact atggtaacat agcatcaaaa aatatacaaa gaaataagaa acgtacaaat
     2821 ttatctatag catcaatggt aattatattt ttcttaatgg caacaatata cacaaagtct
     2881 actagtaact ttttaagtga tggtgtatta aaatattgga tacaaggaga ttatttatta
     2941 cataatattg atataagtac tatacgttca aataataaag gttatgataa aaatgtacta
     3001 caagagataa aggcaattga tggtgtaaca aaagtaaact catataggca taagtggttt
     3061 aatataaaaa ttgatgataa aagtataaat aagaactctg attattggaa aaaaaataaa
     3121 gataatattg aagctagatc agaagtaaaa gatggaatta aggtatataa taattctttt
     3181 gaatttttag gaatagaaga tacagatata ctagaggatt tcttgataaa tggaaaggaa
     3241 aatatagata aatttagtaa acaaccatat ctgtatataa caaagaaatc cagtgattcg
     3301 cttaatataa aaaaaggaga tagaataaaa gtatactttg atattataga ttcaaaaaca
     3361 aataatttta ccaaaacaat atctcaagaa tttatagtat gtggaattat aactacatta
     3421 ccagtaacct cacaagtggg agctgaattt ggcggagtaa tatcaacaaa tcaatttaat
     3481 aagtttacag gaatatcatc ttatgaaaga tttgacatat ggacgagtaa actagccaat
     3541 gataaatatg ttgaaagtga gttaaacaaa ataacagaaa aaacaaataa aggaatttta
     3601 attccataca aagctgaaac agctgaatat gaaaaaattg ataatcaaaa aacactaatt
     3661 atggtattag taactggaat tatagttata ttatctttat ttaattgttg caatactata
     3721 gttactagta ttaatagcag aagtagggaa tttgcactat ttagaggaat aggaatatca
     3781 aaacatgaaa taaataaaat tgttaaattg gaaagttata tatatattat agtaagcttt
     3841 tgtatatcta taatacctat tttaattgta agaagtataa taataaaacc ttttgaaagt
     3901 atcaatttaa taaattggaa atttataggg gctattatac taatagtatt tattttagta
     3961 tctataatca tgataactac actaaaaaca ttgaataaaa ttcaaaatga aaattttatg
     4021 gaagaaataa agactttata gtgaacagcc tataaattaa agaggtttta tatgaattta
     4081 attgcaatta tcgataatgg tgtagatatt gattttaaat aatttagaaa taaaaataaa
     4141 ataagttatc caagttatat gtatgatgta ataggggtac aatgtatagc aaatataaat
     4201 attggcttaa taaaactcta ctcttaagtc tactgtcgtt ttaacacaag actaataata
     4261 agtgtaacct aaaaattatt gataatacaa taaccttgtt tatgataaat aacaaatatt
     4321 aagtgttgta aagatagtaa gtttaaaaaa atatcaaaga tttcaatcac aatgtattgt
     4381 ttatctgtag tgttagctat ttatggtata tatgtattta taaattgtac tgaatatata
     4441 tatactatgc tatctacaaa acatttaaca gtcaaaggaa atgaatatac cattataaat
     4501 tattatatga gtaactttag tcagtatata atatttgcta ttttacttgc atcaatggga
     4561 tttgtaatac aaaagatagt gcatatgcat ttcagtgaga tagaacttag tggtaactat
     4621 tcaacaactg ttagaaatat aagtgatatc tctttagata atgataatga aatgtttaat
     4681 agaggcaata ttgaaaatag tattttaaaa aaataaataa tataaatata taaaatgtga
     4741 ttgaataaag cttagaatac ttagtgtatt ttaagctttt tttattatta agatttcaaa
     4801 gtattaaatt aactatataa aatcatataa aaataatttt aaaatattta aatcattgat
     4861 ttcaa
//
LOCUS       DAMJWC010000138         4810 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMJWC010000138 DAMJWC010000000
VERSION     DAMJWC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4810
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.143"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            185..1336
                     /locus_tag="PC503_003580"
     CDS             185..1336
                     /locus_tag="PC503_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF2529529.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1382..2557
                     /gene="thiI"
                     /locus_tag="PC503_003581"
     CDS             1382..2557
                     /gene="thiI"
                     /locus_tag="PC503_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF2529530.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEESTILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2713..3516
                     /locus_tag="PC503_003582"
     CDS             2713..3516
                     /locus_tag="PC503_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2529531.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3759..4400
                     /locus_tag="PC503_003583"
     CDS             3759..4400
                     /locus_tag="PC503_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2529532.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1936 a          458 c          925 g         1491 t
ORIGIN      
        1 tatagtataa gtatattata ttttactata aaaatttgta ataaagtgaa aaaactagct
       61 tttcatgaaa taatatttta taatttaaga ttgtcttttt aataaagatt aacaaaaaaa
      121 atactataat tagtggtata atagttagag ttgaagattt taaataaagg taggtgtaat
      181 taagttggaa atatacttag acaatagcgc aactacaaaa ccttatcaag aagttataga
      241 taaaatggtt tatgcactta atacggaata tggaaatcct tcttctgtcc atagaaaagg
      301 tgtagaagtt gaaaaagcta taaaagaagt aagacaagat atagctaaat ctctaggagc
      361 gaaagaaaag gagatttatt ttacatcagg tggtacagag tgtaataata ctataataag
      421 aggtattact agtttaaata aaaaaagaaa aaatcacata atatctacta acatagaaca
      481 tccttctgtt ttaaatacat taaaagattt agaagaagat ggttttgaag taacttattt
      541 agaggtcgga aaagatggga aaataaatat agaggattta aaaaatgcga taaagtcaac
      601 tacatgctta gtaagcatga tgcatgttaa caatgaaata ggaactatac agccaatagg
      661 tgaagttgga aagtatttga agggtttaaa agaaaaaatt tatttccatg ttgatgctat
      721 tcagtcatat ggaaaaatta actttagacc atctaaatac aatatagatt ttatgagtgt
      781 aagtgcacat aaatttcatg gtccaaaggg aattggattt atgtatataa aagaaaataa
      841 tcgccttaag cctatgttaa caggtggtgg tcaggaaatt ggaattaggt cgggaacaga
      901 aaatgtacct ggaatatatg gtcttggaga agctgttaga atactaaaca aagatttaga
      961 tgctgttatt tcgaaagtag ataacttaaa aaatatatta aaaaatgaaa taattgataa
     1021 tatagaagat ataaaaatca attctccaga agacggagta tgtcatatat taaatgtatc
     1081 atttagaggg acaaaaggag aagttttact tcattactta gagcaaaaag gtatttatgt
     1141 atcaactggc tctgcatgtt cttctaaaaa gaaaggtagt tacgtattaa atgctatagg
     1201 tcttacaaat gaagaaataa atggaacaat aagatttagt ttatctgata tgaatacaga
     1261 agaagaaatg ttagaagctg tgaaagtttt gaaagaatca atttgtgact taaggtcaat
     1321 aatgaaaaga aaataaagaa tactgtataa atagtgataa taaattagtt taagaggtga
     1381 aatggtgtat aatatattaa tagtaaagta tggagaaatt ggagtaaaag gaaagaatag
     1441 atatatattt gagaataggc ttataagaaa tataagaaat atgttaaaac caattggaag
     1501 atttaatgta tataaagagt atggaagaat atatgttgat ttagaagact atgattatga
     1561 agaagtaatt gaagaagtta gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag
     1621 agctaaaaaa gattatgata cattaaaaga aatagcttta aaaatgttag aagaaaaaat
     1681 agaggctgga tataaaactt ttaaggtaga gtcaagaaga ggagataagt ctttcggatt
     1741 gacttctcaa gaaatgagta tggatatagg tggatactta ttatcaaagg taggagatag
     1801 gattaatgtt gatgtaagaa atccagaagt taaaataaag tgcgaataca gagaatttca
     1861 tactatggtc tatagtgata ctatacctgg atatggtgga ttgccacttg gaacgaatgg
     1921 tagagctatg tctcttttat caggaggtat agatagccca gtagctacat ggatggttgc
     1981 aaaaagaggt atggaagtag aggcagttca ctttcatagt tatccattta caagtgaaag
     2041 gtcacaggaa aaagttaagg atttagctaa aatactggca aaatactgtg gtagagtaag
     2101 gcttcataaa gttaatatct tagaaataca aaaagcaatt ggcgagaatt gtaatgaaga
     2161 agaatctact attctttcaa gaagatttat gatgaggata gcgcagagac tttctgaaaa
     2221 aagacattgt gatgctttaa ttacaggtga aagtattggg caggttgcat ctcaaactat
     2281 acaaggactt acttgtacta atgccgttgt agacttacca gtgtttagac cacttatagc
     2341 aatggataaa tcagatatag ttgatatagc caaaaaaata gggacttttg aaacatctat
     2401 agtgcctgaa gaagattgtt gtagtgtatt ttctcctaga aagcccgtca ctaaacctag
     2461 attagagaaa atagaaaaat ctgaaacagc acttgacatt gaaaaattag tacaggatgc
     2521 tattgacaaa atagaggtag aggatattga gttttagcat acaagttatt taattactaa
     2581 attgaatatt gagtatatta gtagttctgt aagtatatta gtagttctgt tgaaaggatt
     2641 tatgtagaca atttattaat atgtagtatt taaaaataag tactataatt ttatttaatg
     2701 ggaatgatta ttatgaataa aaagggtttt acactaattg aattgttagt agttatatct
     2761 ataataggca ttttagttat agtagctgtt ccagcattgt ttagaaatat agaaaaaagt
     2821 aaagcagtta catgtctttc taatagagaa aatataaaga ctcaaattgt tattgcaatg
     2881 gctgaggaat caagtaaagg caagaatgaa gtcatgaaag aggtattaga aaacaaagat
     2941 ggtaagtact ttgaaacaga accaaagtgt aagtcaggtg gaatatattc agcaacgttt
     3001 gatgatggtt atgatggaat aactggaata gaaagcattg caaaagtgta tgttacttgt
     3061 acaaaacatc cagatggtgt tgaaatggct agggatatac atcaaagtat gaaagatttg
     3121 attgcatcat ttgcacaaga cccttctata ataccaggag cctcaaaggg taatgatgat
     3181 tttagaaaat atttattaga caataaatat aaaaatgggt ggcctacaat tccagatgaa
     3241 tttaaggcaa aatatggatt aagtaaggat acactatata tacaaccata tgcatataat
     3301 cctactaaat ctgatgctac tgtagttgta tttgcaaata ataagactgg gggtaattgg
     3361 tatacttccc tagtttacga ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt
     3421 tctgttgcag gtaggtcatg ggatgttgac acagatagtg ttaagtctgt aaaaacagag
     3481 attcattcta aagagggatg gggtccttta aattaatata tcatgtttta ttaatctggt
     3541 attgattaaa ctatagaaaa gagcagtttc tatagatgac gaataccaga ttttcattta
     3601 tatatataat tgagatatat taaaagtgtt tatattttta agtcttcaca tacaagctaa
     3661 aaataattat aataatattg taaagaaatt taattataag attaattttc tgaagattta
     3721 gtatttgtac taagaaatac ataaaaaggg gaatagatat gaataataat tttcaagaca
     3781 accaaacaat aaatttaata caaagtcgta gaagtatacg aaaatttacg acagaacaaa
     3841 ttagtgatga gcaagtaaac acattattac actgtgcatt tgcagcacct tcaggatgta
     3901 ataaacagcc ttggcacata actgttgtgc aagaccagaa acttttaaaa gagattagtg
     3961 atgatacttt atctaggatt catgaggtga gtaatgttga gataaataaa aactttaagt
     4021 tattttatgg tgctccaacc gttttattta tttcttatga tgaaagtagt tcatgggctc
     4081 catatgatat aggaatactt acagggaata taacaacagc tgcacaagca ctagggcttg
     4141 gaagttgtat aataggaatg gttagaggtt tatttacacc tgttgaacaa ggggatattg
     4201 aaggtcttgt gagtgtattg gataaagaag atgtaaaaga atcagagtca ataaagatga
     4261 agtttgatac aaataaaaaa tacagagaac tacttgatat accagaaggg tattctgtac
     4321 catttggtat tgctgtaggt attccagatg gaaatttacc aaatgctaga gaggtagttt
     4381 acaaagtttc cagagtttag gataaagtat tgcaagaacc aatcagttac ttgaagaatt
     4441 aaatcagtaa tatacaaata aattgatgga agaggaagct atttaaaaag tagtttagat
     4501 ttttcgttgt aaaataatta aataaagaat aaggtgataa gtattttatt tattatctta
     4561 ttctttttta tttttgtttt gtagaatgat aaaaataagg attaagtgta ataaaataga
     4621 aaacaagtat gttaatttta agtatatgct ttaaaattta tccaagttaa aaatttaaga
     4681 tatcttttca gtataatgga aaaaatgtca aaatattgaa atagggaaaa aatagtgata
     4741 taataagaaa aaatagagaa aaaaagtaac ccttagttat aaaaaagtta ctatttattg
     4801 aaaatttaga
//
LOCUS       DAMJWC010000139         4678 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMJWC010000139 DAMJWC010000000
VERSION     DAMJWC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4678
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.144"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(132..935)
                     /gene="proC"
                     /locus_tag="PC503_003584"
     CDS             complement(132..935)
                     /gene="proC"
                     /locus_tag="PC503_003584"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2529533.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEKFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(1260..3629)
                     /locus_tag="PC503_003585"
     CDS             complement(1260..3629)
                     /locus_tag="PC503_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2529534.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(3634..4542)
                     /locus_tag="PC503_003586"
     CDS             complement(3634..4542)
                     /locus_tag="PC503_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2529535.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
BASE COUNT         1373 a          907 c          512 g         1886 t
ORIGIN      
        1 actcaatcat taaattcctt tttatagtaa attactctta ttttacttat accaaataca
       61 tttatgtata gatataaata agcactaaaa aaacaattca agaaaccata tagtaaactt
      121 aattacatct gttatttgct catatcttta gacttatcta tacaagcaac aatagatttt
      181 ataactgctg ctctaaagcc ttcttcttct aataccttaa cagcttctat agtagttcct
      241 gctggagaac aaaccatatc ttttaattca cctggatgtt ttccagtttc aagaaccatc
      301 ttagctgacc ccattactgc ttgagatgca aatttataag cttgttgtct tggcattcca
      361 gctaatactg ctgcatctgc catagcttct ataaacataa atacatatgc aggagaagaa
      421 ccactaatac ctgtaactgt atccattaaa tattctgata ctatttctgc ctcaccaaaa
      481 gattcaaaca gagccttaat catatttaac tcttcatctg ttacattact atttttacaa
      541 agagctgaca ttccttcgcc aacaagggct ggagtattag gcattactct tactattttt
      601 ttatctgaac ctataaaact ttccagactt tctatagttt tacctgctgc tatagatact
      661 attattttat ttgcatctat taattcttta agtggagtta aagccttttc gcatatatta
      721 ggtttaagtg ctactattac cacatcagaa tttgtaacag ctacctttga atcagttgta
      781 gtatttactc caaatttttc ttttacttta tctaaggcaa cttggcttaa atctgataca
      841 gttatatctt ctgcctttac taatcctgac tgtactatgc cacctatcat tgcacttccc
      901 atattccctg aaccaataaa tcctaaagtt ttcatatcaa atctcctttt ttctattagt
      961 tttattttaa agtagctaaa ttgactttat tttaactgct taaaattatc ttatttttat
     1021 aaaatataac cttattataa ctataataaa ttattctttt gtatgtatta cttactaata
     1081 tgtgtatgat ttactaaata taaatttaac gattttttca ttaaacttaa cgagctaact
     1141 tcctatttag aaagttagct cataattaat ctaaaatttt aaaaatggaa tcaaaccatt
     1201 tatactttat tatatcagtt acgattttat atagtaagaa gttttattta caagcaaacc
     1261 tagaatgttt gctcagttct tcctattatc tcatcttgta gtgttctact taaattattg
     1321 aaatggtcac tatatcctgc aactctaact attaagtctt tataatcctg aggattcttt
     1381 tgagcctcta acagtacatt tttatcaaat acattaaatt gtatatgatg accatccata
     1441 ttaaagtatg ctcttactag attagccata ttatctaacc ctttttctcc ttgaactact
     1501 gatggtgcaa atctttgatt taataatgtt ccaccagttt ttatgtggtc catcttagca
     1561 caagatttta taactgctgt aggtccatta gtatctccac ctttttcagg tgaaattccc
     1621 tctgaaactg gttttgcaca aagtctacca tttggacttg ctcccataat ttctccaaag
     1681 tatatatgac aagttgttgg taacatatct actctgtatt ctccaccaca aacagttggt
     1741 ctaccagtta cctcattgta atatgcattg aatatctctt gcattatttc atcagcataa
     1801 tcatcatcat ttccatattt aggagtctta tttgaaacta aattaagtat agcttcatat
     1861 ccttcaaaat tagcatcaag tgctttaagc aatgtatcca tatcgaattt tttcttatca
     1921 aatacattat attttattgc tgttaaacta tctgttatag ttcctatacc aacaccttgt
     1981 atatatctag tgttgtatct tgctccacct ctttggtaat ccttgccttt ttctatacaa
     2041 tcatcaacta ttgtagacat aagtggacaa ggcatgtgtt ttgcacatat attttctatc
     2101 acagcatttc cttctatttt tatgtcaatc atataatgta attgcttttt aaatgcttca
     2161 aatagttcct cataagattg gaaatttcta gggtctccag tttcaatacc tatttgtttt
     2221 ttactaattg ggtcatatcc attatttaat gttaattcaa gtatttttgg aatgttcata
     2281 tatccagtta gaacatatgc ttctttacca aaacatccag tttcaacaca accactggtt
     2341 ccaccaagtc ttgcatcttc tatagttttt ccagcttcca taagctcttg aactattgct
     2401 tcagtattat aaaatgctgg ttgaccccat ccttttcttg atatttcaca agctctcttt
     2461 aagaattttt gaggagtctt tttacttatt tgaacatttg aactaggttg tatcaatttc
     2521 atttcatcca taacatcaag tattatataa ctaacttcat taacaccatc ttgaccatct
     2581 ggatttattc caccagtgtt tatatttgca aaatctgtat atgtgctact ttcttttaat
     2641 gttataccaa cttttggtgg tgctggctga ttgttaaatt taacccataa acattcaagt
     2701 aattcttgtg ctctatctct atctagtatt ccattttcta catctctttc atagaaagga
     2761 tttagatgtt ggtcaagtct tcctggagta aaagcatccc atatattaag ttcagtagta
     2821 acccctatat gaacaaacca atacatttgt atagcttgat gataagtttc tggtttgtga
     2881 gctggtacaa catcacaagt ttcagcaatt agtaataaat cttttttctt agcttcatct
     2941 gtttcttctt ctgccatttg tcttgctttc tcagcatatc ttttacctaa tataaccatt
     3001 gcatcacaag ctattgccat agcttctaaa tctgcttttt tattatatgc atctaaatca
     3061 ttaagaaaat ctagctcttt taatcttgct tctatgtctt tctttaaatc taaaaatcct
     3121 tttttatata ttgtatctcc acaaactgta tgtcctggag ctctttgttc cataaactct
     3181 gtaaacatac ctgcttcata tgctgctaac cactcaggtg tcattgcatt tattatctta
     3241 tctcttgttt gtctcttttt ccaaaaagga attatttctt ctttatgtat ttttctagct
     3301 tcttctgata cgctaaaatt tattatatct ctattgtgca ttacttctaa atcttccatt
     3361 gtatgacaac aaatttctgg atatgttggt gctccattag gagaatcacc tttttcacct
     3421 actattaatt ctccatcatt tatgctaaga gttctattct caatataatg cttaaatgat
     3481 aaagcacgaa gtacaggaat ctctacactt ccctcatatt ttttataagc ttctgtcata
     3541 agtactgctc tttcaataga tatgtgtggt tctgcattaa tactttcttc tcttaatttt
     3601 ttagttctct caaaagttcc tcttgccatt ttattaccct ccaatcttag tattgaaatt
     3661 acttgcttca aacagtcttt ttatttcctc taatttttct tctgatggtc tttgtagttc
     3721 ttctccttca tactttttat aaattttatc atacttgtgt ttaccaatat tatgatatgg
     3781 aagaagactt actgcttgta tattcaaagg ctttaaaaac tctatcattt ttttaacctc
     3841 taaattttca tcatctacat ttactcctac aattaatggt attcttatat ttatgttagc
     3901 ccctaattca cttaaaatct taacattttt cagtattaag tcatttgatt ttcctgtaaa
     3961 ttttatgtgc ttatcttcat caataagctt aatatcatat aaaaacaaat ctgcacattt
     4021 agcaactctt tcataatttt ctgactttgc atagccacat gtatcaattg ctacatggat
     4081 tccctttgat ttgcacatgt ttattactcc acaaatgaag tccatatctt gagccattac
     4141 ttctccacct gatagagtta ctccaccacc tgattcttca tagaaaattc tatccttctc
     4201 tatctcttta accaaatctc ttacagaata ctcttgacca acaatctctc ttgcattgtt
     4261 tacacaatag tctaagcaag tttcacaaaa ctcacactta tcttggtcta agcatatttt
     4321 tgtttcacct ttgtaaattg ccttatgagg gcatatattt atacatgctt cacattttga
     4381 acatctttct tcattataca aaacttgttt tgtatatgtt tgactctctg gattatgaca
     4441 ccaaacacat tcaagtggac accctttaaa aaatactgta cttcttatcc ctggtccatc
     4501 atgtatgcta catttttgta agtttataac taatggattc atgatttttc acccctaaat
     4561 aatatccatt ccattttttc atttttatgc aattcatctt catagaatat acctatgaaa
     4621 agcatttcta caattacata atactatatt cgttattatt ttgtctatat atttttag
//
LOCUS       DAMJWC010000140         4538 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMJWC010000140 DAMJWC010000000
VERSION     DAMJWC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4538
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.145"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            268..1743
                     /locus_tag="PC503_003587"
     CDS             268..1743
                     /locus_tag="PC503_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2529536.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1830..2243
                     /gene="speD"
                     /locus_tag="PC503_003588"
     CDS             1830..2243
                     /gene="speD"
                     /locus_tag="PC503_003588"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF2529537.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2273..3124
                     /gene="speE"
                     /locus_tag="PC503_003589"
     CDS             2273..3124
                     /gene="speE"
                     /locus_tag="PC503_003589"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF2529538.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3114..3992
                     /gene="speB"
                     /locus_tag="PC503_003590"
     CDS             3114..3992
                     /gene="speB"
                     /locus_tag="PC503_003590"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF2529539.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4172..4372)
                     /locus_tag="PC503_003591"
     CDS             complement(4172..4372)
                     /locus_tag="PC503_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2529540.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1818 a          501 c          765 g         1454 t
ORIGIN      
        1 aaaaaacaaa ataataaaaa ataagaaagt ttataaatac taagttttaa aaaaattaat
       61 ataaacaaca aaaaaataaa aagtttataa atattgatat agctaatgta tatgtttttg
      121 agtaacttca aaaaaacact tgtaaaaatg ctgagatgtt aatataataa atatcatgag
      181 tttaataaaa gtaaaaataa aaaatagaaa taataaataa taaatattaa aaatatttga
      241 atatagagag gagatgaatt tgaaatcatg gatagcgagt ttgcaaatgc agttgaatta
      301 agctatgagt gtgctccatt attagagtcg ttaaaggaat actcagagaa agatatagct
      361 tgttttgatg tgcctggaca tgtaaaaaat agaggtgtag ctatattaaa taaatatcta
      421 ggtgaaagtc tcatgaaaat ggatataaat tcatcaccaa ctatggataa tgtatctgcg
      481 ccaaatggga ttataaaaaa tgcacaagat ttgctagcac aagcatatat ggctgatgag
      541 gcattcttta taacgaatgg cacaactcaa gcaatacatg caatgatttt gagtgttata
      601 aaaccaggtg aaaaagtatt acttccaaga aatatacata aatcagtaat aaatgcgtta
      661 atactttgtg gaggaatacc aatatttata caaccagaat ttgatgaaaa actaggtata
      721 agtttaaata ttactcttga aaaagttaga acagagatag aaaaagattg taatataaaa
      781 gcattatttt tccttaatcc aacttactat ggagtttgtg cagaccttga gagtattata
      841 gaactatgcc ataaaaataa tgttttagtg ttagttgatg aagctcatgg tgcacatttt
      901 ccatttcatt tagatttacc tccttctgca ataagtttgg gagctgatat ggtagctgta
      961 agtatacata aaactggagg agcattgaca caatcttcag cactcttatt gaatagagat
     1021 aatgtaagtt ttgaaaaggt tcttcaatca atcaatatgc tacaatcaac atcagcatct
     1081 tatttgctta tggcaagtat agatggtgct agagttaatc tagttgagaa tggtgaaaag
     1141 caactgtcaa aagcattaaa tctatctagg tatgcaaaat ctaaattaaa caaaattgat
     1201 ggaataaaag ttttatctac agaaatattg aaacaaaaag gtgttaaatt tatagatgaa
     1261 acaaaattgt gtataaatgt aaaagaatta aatttgactg gatttgaagt atacgattta
     1321 ttatataaaa atttttcaat tcaagtagaa ttgggagatt catataatat actggcactt
     1381 gtgtccattg gaacaaataa atcagatata gatagattag taaaagcact ttctataatt
     1441 gcaaagattt atagaaaaga atcaacatta aatgaattta atatggttca aataaatcca
     1501 attattaaac ttaatccaag agaagctttt tatgcaccaa aggaaagtgt agaaatcaat
     1561 tcatgtatag atagaatttg tggagaatca ataatggcat atccaccagg tataccgatt
     1621 attgctccag gagaattgat aacagaagaa attatggagt atattatttt cttaaaaaat
     1681 agcaatgcat atcttacaga tgtacaagat aaaaacttag atagaatatt agtaataaaa
     1741 taaattactt tattttgcaa gggcaagtat ttgttaagta gagtttatca aatagaactt
     1801 attaaaagta taaaggagtt ggggttgaaa tgaaatttga aacactagga agacatatac
     1861 tagtagaata ctataattgt gatgaaaacg tacttaaaga cccacgtctt atagaaaatt
     1921 ttatgaatga ttcagcatta aatgcaaaag cgacaattgt ggattctgta ttccaccatt
     1981 ttaatccttg gggggtttca ggagctgtta taattgctga atctcatttg acaatacata
     2041 catggcctga atatggctat gcagcagcag atttttttac ttgtggtgat atagacccat
     2101 ggaaaagttt tgaattatta gagcaacttt taaagtctga aagaagcgag tctacagaaa
     2161 ttccaagagg cttaactaca aaaattaaaa aatattcaaa aaaagattta ggtaagatta
     2221 ctcataaacc agaagcagta taaaacatac aagagaaagt gaggattatt atatggaact
     2281 ttggtataca gaagaatgga cagaaaatgt aagattttct ataaaagtaa ataaacatct
     2341 atttgaagga aagtctcaat ttcaaaggat agatgtgttt gatagtgatg aatttggaaa
     2401 atttctaaca atagatggat taatgatggt aacatataaa gatgaattta tataccatga
     2461 gatgataact catgttccta tggctacaaa tttaaacata aagaaagtat tagtcatagg
     2521 tggaggtgat ggaggtacag taagagaatt aagccgttat cctcaaatag aaaagattga
     2581 catggttgaa atagataaaa tggttgtaga tgtatctaag gagtatatgg atatatgctc
     2641 atgtaaatta gatgataaaa gagtgagttt atattttgaa gatggtgtta attttgttaa
     2701 gtgtgcacat gataaatcat atgacctgat aatagtagat tcaactgacc caataggacc
     2761 aggtgaaggg cttttctcaa ctgattttta taaggattgt tatagaatac tgactgatga
     2821 tggaatttta gtaaatcaaa gtgaaagtcc gtattttgac tttaatgcta aagagatgaa
     2881 aagagctaat aaaaaattaa aacagatatt tccaatatca gaagtttatc aagcacatat
     2941 accaacatat ccatctggtc actggttgtt tggatttgct tcaaaaaaac ttaatccagt
     3001 aaaaaatcaa gatagaaatg gatgggagaa attaagttta aaaactaaat attataatag
     3061 tgatatacat ttaggttcgt ttatgttacc tcaatacgtg aaggagatgc tagatgaaga
     3121 ataatttcta tcatatgaac acttttatga gtatggacaa aaattatgaa gaatctaatc
     3181 ttatagtatt tggtgttgga tttgatggaa ctacttctaa cagacctggg gctagatttg
     3241 caagtagctc tatgagaaaa gaattttacg gtcttgagac atatagtcct tttttagatt
     3301 tggatttaga ggattataat atatgtgatt atggagattt agaaattagt gttggaagta
     3361 cagaacaagt cttaaaagaa atctatcaag agacatataa gattgttaga gattcaaagg
     3421 taccctttat gattggagga gagcatttag ttacattacc agcctttaaa gcagtacatg
     3481 aaaagtacaa tgatatatat gtaattcatt ttgatgccca tactgatttg agggaagaat
     3541 ataataatag taaaaattct catgcaacag taattaaaag aatatgggat attgtaggtg
     3601 ataataaaat atttcaattt ggtataaggt ctgggacaaa agaagaattt aaatttgcta
     3661 cagaagaaaa acacacatac atggaaatag gaggaataga tacgtttgaa aatatagtta
     3721 atatgctaaa tggaaagaat atttatctaa ctatagattt agatgtattg gatgcatctg
     3781 tgtttccagg aacaggtaca ccagaacctg gtggtgtaaa ttatagagag tttcaagaga
     3841 tttttaagat tataaaaaac tctaatataa atatagttgg ttgtgacatt gtagagttaa
     3901 gccctgatta cgatacaaca ggtgtatcga cagttatagc ttgtaaaatc ttaagagagt
     3961 tatgcttaat aatatctgat aaaattaaat agagtatttt atataaatag tatatattat
     4021 aatataagaa gttattttaa aaaagttagt ttaagtttga cgcttttcta aagtaacttc
     4081 ttatttttgt aattaaaaat aaatataata aacaacaaaa aagagccctc gatagctcct
     4141 tttctaaaat atatatattt aaattaaata attatattct atttacgttt tcagcttgag
     4201 gtcctctatt accttgagtt atatcaaagc taaccttttc gccttcttct aaagttttgt
     4261 atccatcatt ttgtatagct gagaaatgta cgaaaacatc atcttctccc tctacagata
     4321 tgaacccaaa tcctttttca ttgttaaacc attttactat tccgtttttc attataagaa
     4381 aacctccgca ttattaaaaa atacaaacta aaaaaataag tctgttctat taatataaca
     4441 taaattttaa ataaaagcaa ataaaatttt taaaaaaatt aattactttt agaatttaat
     4501 aaaaattgtt aaattataca gtgagaagta ttgtaaaa
//
LOCUS       DAMJWC010000141         4524 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMJWC010000141 DAMJWC010000000
VERSION     DAMJWC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4524
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.146"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(100..645)
                     /locus_tag="PC503_003592"
     CDS             complement(100..645)
                     /locus_tag="PC503_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2529541.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(763..2586)
                     /locus_tag="PC503_003593"
     CDS             complement(763..2586)
                     /locus_tag="PC503_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529542.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRILNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSILLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(2599..4374)
                     /locus_tag="PC503_003594"
     CDS             complement(2599..4374)
                     /locus_tag="PC503_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529543.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         1480 a          801 c          394 g         1849 t
ORIGIN      
        1 ttagaaataa aaaataaagt acaaataatt aaaaaatatc tcactcataa ctttaaaaat
       61 tataagtgag atactcctaa aatctacttt atattaaatt tattttccaa aatatctatt
      121 taataatcct aaaaatgctt taccatgtct agcttcatct ttacacattt catgtactgt
      181 atcatgtata gcatctaatc ctaattcttt tgctttctta gctaatttta attttccatc
      241 agttgcacca tactcagcat caactctaac tcttaagttt tcttttgtat ctgcaactac
      301 aacttctcca agaagttctg caaatttagc agcatgttca gcttcttcaa gagctattct
      361 cttataagct tctcctactt ctggataacc ttctctatca gcttgtctac tcattgctaa
      421 atacattcct acttctgtac actcaccaac aaagttagct cttaatcctt cgattatttc
      481 ttcatctaca ccttgagcta ctcctattct gtgctcatca gcccaatttt tttcgccttt
      541 catttcttca aatttatcag ctccaacttt acatactgga cattgtgctg gtgcagcatc
      601 tccttcatgt atatatccac atactgtaca aacaaatttc ttcataatta ctttcctcct
      661 aaattttata tatcaaatta aattttttat ttattaagtt agtctatata tacccgcacc
      721 atataccttt aaacaatttt tttaaaagtt ttttctaaat acttattttc cctgtgtcaa
      781 taatatgttt ctataataat gtccctttaa ttttatcaat tctttatgat ttcctgattc
      841 cacaattcta ccattttcta aaactattat attatcacaa tttgatatgg tacttaatct
      901 atgagctata attatacttg tctttccata agttaaatta tttattgctt cttgaatttt
      961 agcttctgtt gctatatcta tgttacttgt agcctcatcc aaaataagta ttggagcatt
     1021 ttttaatact gctctagcaa tacttattaa ttgtttttga ccttcactta aatcttcacc
     1081 cctatccgat aatacagtac tatatccttc acgcatttta actataaatt tatgtgcatt
     1141 tgctatttta ctagcatata taacttcttc atcagtagcc tccagatttc cataccttat
     1201 attttccata actgtatcat tgaatatata accttcttgt ggaactactc caaaacaagt
     1261 tctcaaatag tttctgttaa tagagtatat atccttacca tctaaaagta tacttccttc
     1321 atctatatga taaaaatttg taattagatt tataatagtt gtttttccac ttcccgtctc
     1381 tcctatgatg gcatttgatg tgccagcttt gatttttagg tttatattat ctaaaatttt
     1441 cttttttgaa tcataagaaa aacttacatc tttaagctca atttctccct ttacaaaatg
     1501 agagtttaaa ttaccatctt tattatcgtt aatctcactt ttaaacatgt tatgcacttc
     1561 ttgctcttct tgttcatcta taatttcaaa aactctttca catccagcta tggctgaaag
     1621 taatgtatta aatagatttg ctaattcatt taaaggtctt gtaaattgtc ttacataact
     1681 taaaaaacta gctataaccc ctatggttat aatatcttta gatgcaagaa tgcctcctat
     1741 aatacatata gttgcaaatc ctatattact aatcacattc ataataggca ttaaaagaga
     1801 agtgtaaatt tgcgatttaa gggaaatatt tagaattcta tcattgactt ctttaaaatc
     1861 atttacagat tttctttcat aattaaaaga ttttactaca tttatgtttg atatcatttc
     1921 ttcaatatgt gcatttagtt ttcccaactc aacttgttgt tgcttaaaaa aaactctagt
     1981 tctctttgca ataaaattac tcacaaacat tactatcggt attaatatta cactgcaaaa
     2041 ggttaaaatt gggcttaata caaacatcat aataaaagtc atcaatatgt ttaagattcc
     2101 tgtaattaac tgtactaatg aatttgatat tcctgtactg atattatcaa catcatttgt
     2161 cactctactc ataatatctc cagtagaact tttatcaaaa aaggttattg gtagattttt
     2221 aaattttaaa aataaattac ttctcatttc tttaactata ctttgagata atctagctgt
     2281 acatatcccc ttagacagtt taactgaaaa ctcaattata taaaatgaaa gtaaaataat
     2341 tattcctttt aagaaaatgg attttgaata agtatcgata tctattatgt caactacctt
     2401 tccaatagta tatggtatta cagttgatat aattgaatca attattacta gcaaaaaaat
     2461 aaatctagta atcttcttat cttttttaaa gtacataaaa attcttttaa acgttttttt
     2521 aaaatcttta ggcttttctt ttttctttaa tctactgacc ttctgatttc cagtacttaa
     2581 attcaatata cttcctcctt aatttacatc ttcacttact aaattctgca acgcaaaaat
     2641 ttttttataa attggagaac taaccagtaa atcttcatgt gtagcaaatc caaccacctc
     2701 accctcatcc aagactaaaa tcttatcaca gtcaattata gaactaatct tttgtgaaat
     2761 agttattaca gtacatttct tactttcctt ttctcttaaa ttacttatat actcttttat
     2821 attctttctt ataattgtct ctgtattaat atccattgca ctaaaacaat catcaagaat
     2881 taatatttgt ggttttttgg ctatagctct agctatagta attctttgtc tctgtcctcc
     2941 tgataaattt ttaccccttt ggaataaaac ttcatcataa gtattttcga gttttgttat
     3001 aaattgattt gcatttgcta tttcacatga ttttacaaca tcctctttgc atatatctct
     3061 atttcccata actacattct ccaatatact ttttccaaac acactactat tttgaaatac
     3121 tacacctatt cttgccctta aactttcttc agaaatactg tatatactac gtcctccaat
     3181 cttaatatca cctttatcaa ttatatataa tttttgaatt aaatttacta aagaagtctt
     3241 tcctgaacca gtttgaccaa tcacaccaat attttgacct tcttctattt taaaggatac
     3301 gttttttaat attttttcat ctgtattttt gttatacgaa aaatctacat tttcaaaaat
     3361 tatatcacag tttacaaact ttaaatcttt ttctccaaca tctaaacttt cttctctctc
     3421 aattacttct tcattctcat caaccaaaac ctcacttatt ctctcataag atgcttttgc
     3481 cctaacaaaa acattaaaaa catgtgaaat cattataaga gatgttaata ttctagtcat
     3541 atagtttaca taagcaacta taatcccaat tttaatttct cctgaataaa ttaaatgcct
     3601 tccaattagt aatattatta ttatggaaac attaatgatt attgtaattg tcggtctaaa
     3661 aaatgacatc atagttgtag cttttctact atttttaaaa agttcatcat ttaactcttc
     3721 aaagctttgg ttctcataat cgtatctaca aaatagttta actactttta ttccacttaa
     3781 aaactgtctt aattttgaat ttactttatc tgtactttct tgtacatttt taaataatct
     3841 ataccctatc ttcatattaa gcaatattat aataaatata attaaaactg caattagaat
     3901 aattattgac atctttaaat ttaattttat agctataatt aaacttccta tacacattat
     3961 tggtgacttt ataaaaactc tcatcattcc attaacgaat tgttgcattt gattgatatc
     4021 attagtaatt cttgttatta atgaagctct accaaattta tctatttgtt ttaatgagta
     4081 tgtatttatc ttttcaaata catcctgtct taaatcataa gaaaaatgct gagaaactct
     4141 tgccgagatt acacttctta ttattgcaaa tattgcacct aaaaaagtta tacctatcat
     4201 tatagctcct gttgatagta tgtagtctaa gttcttattt gaaaccccta tatctattat
     4261 ttttgccatt atagttggtt gagctaaatc acaaaaagct tccaatgtta aaaaaaatac
     4321 tgctgttaga aataatacta tatatttttt tatgtatttt ttaaaatacc tcattcaatc
     4381 atcccttcat agaattttct cattaccaaa agtatatcat aatggctaat ttaattgatt
     4441 atatcaatta taaatatttg atttattatt aatttttata ccatatattt tataaattat
     4501 ttgtttttat ttcctatatt tata
//
LOCUS       DAMJWC010000142         4482 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMJWC010000142 DAMJWC010000000
VERSION     DAMJWC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.147"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            22..690
                     /locus_tag="PC503_003595"
     CDS             22..690
                     /locus_tag="PC503_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529544.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            849..1355
                     /locus_tag="PC503_003596"
     CDS             849..1355
                     /locus_tag="PC503_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2529545.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1483..2499
                     /locus_tag="PC503_003597"
     CDS             1483..2499
                     /locus_tag="PC503_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2529546.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTPANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2853..3557
                     /locus_tag="PC503_003598"
     CDS             2853..3557
                     /locus_tag="PC503_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF2529547.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3852..4331
                     /locus_tag="PC503_003599"
     CDS             3852..4331
                     /locus_tag="PC503_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2529548.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1883 a          376 c          764 g         1459 t
ORIGIN      
        1 ttttttaaag ggtgattttt tatggaaaat ataactagtt attttacaac aatactatgt
       61 gtatttatat gcttatcatc tgtatttata tttactcaac tagctagagt atttattaat
      121 aagaagaaga ttaatcaaaa aattaaatca agaaacggat ttaggtatga tagagatttt
      181 attgaagcca gaagagaaga aatacatata aaggataaca ataataataa aaataagagt
      241 aacaataaga aattaaaggg agaaaaagta tttaaatacg ataatggtga tttatataaa
      301 ggtgagtttg ttgatggaaa gaaaaatgga tttgggatat atattttttc aagtaaggaa
      361 aagtatgaag gattatggaa agatgacaag atgcatggaa taggaaaata tacttataga
      421 gatggttcaa tatatacagg tgaatttaaa tacggattaa aaaatggttt gggaaaatta
      481 acatatccca ataatgacat ttataaggga tattttttag ataataagaa aaatggtaag
      541 ggtgtattat ataaaaatga tggaaataaa caagcaggaa tatgggaaga tgatgaacaa
      601 tgtaaaagtt tagattttaa agatttaaat aataataaaa taaataatgt ttatcaaaat
      661 agattaaata acaataaatt aaaagtttaa ttattctaat aaaaaaatct ttatttatga
      721 tggaatatag gatatatcta tgttgtaatt tgtaaaatct tcctatatca tataaaatta
      781 agtattgatt agtctattac ataaatatag aatataaata tatccattta ataataagga
      841 gaagagatat gaaagagtat gtagttgtgg atttagaaac tacaggatta gatccatata
      901 aaggttgtga aataatagaa ataggaataa cagaaataaa aaatgaacaa attgtaaaaa
      961 actattcaag gttgataaaa cctaagggga taatttcttc atttataaca gaattgacac
     1021 atataagtaa tgaaatggta gaaaatgaag aaccactaga attagtttta cctagattta
     1081 gaaaatacat aggtgataga actataattg cacacaatgc gaaatttgat ttaaaatttt
     1141 taaattacta tcttagaatg ttagatttag aaccaataaa caattatata tgtacagtag
     1201 agttattaaa aaaatgtaaa agttataaag gaaaaaacaa gaaacttgaa acagcttgtg
     1261 cttattacaa catagagaat ataaatgctc atagagctga cagtgataca ttagcaactg
     1321 caaaactatt tttgaaaata aaagatgaat attaattata aatatagaga aaattagtga
     1381 aaatatcctt tataaaattg acccttaagc ttacaatttt gttctttgat ttattttgta
     1441 gaacaatgta taatgtacct tatatgaaga agggagacta aaatgggtta ttacaatgat
     1501 aatgataata ataaaataag acgtaaaaaa attagtaaca gcaaagatag taataaaaaa
     1561 tctaaacatt cttatactcc ggcaaataaa aaaaataaaa gttctaagac aagttctagt
     1621 aaaagaatga gtgaaaaagt agattcacag aatcttataa aaagagatag agatagtttt
     1681 acaagagata atgtaagacc tttaaataca gattacaatc aaagagaaag aagaagagtc
     1741 gagtataaac aaagagagaa aaaattaaaa agtaaaaaaa gaaaaaaaca aaaaaggatt
     1801 agaatagtta gagcattatt atctattatg ttagttgcac taattatatt ttcagtggca
     1861 ggtgcaatat ttacagtttc agctataaaa gggtcaccag aagttactaa aaagttaatt
     1921 aggtctaaat atataagtag tgaggttgta agtataaaac aaatgccaaa tgatttaaaa
     1981 catgcaatag tttccataga agatgagaga ttttataagc ataaaggagt agatgttatt
     2041 tctctagtta ggtcagtatt aaacaatgtg tttacagata caacacaagg tgcaagtact
     2101 atagatatgc aagtttcaaa aaacctgctt actagtaatg ataaaactat gaagcggaaa
     2161 ataagggata tgtataatgc taagcagatg aataagatta tgactaagga tgaaattctt
     2221 gaagcatatt taaataatat gtatctaggt aaaaatgcat atggagctgc aaagggagct
     2281 gaagtctact ttggtaaaaa agttagtgaa ttaaatttag ctgagtgtgc tatgttagct
     2341 ggtatgacaa ataatcctgc aaggtatatt gaccatggag aggctaagaa gagacaagtg
     2401 attgtactgt ataagatgca tcagcttggt tatataactg ataaggagta tagaatagca
     2461 aaagctgatg acactccatt taaatcagaa attgattaaa attgtaagaa tatagtattt
     2521 tcaatagttt aaacaaacaa aaatgtaata aaaaaggtga tttgccaccc atttgccacc
     2581 ataattataa tctaatggca aattgtttta atgtacaaac tagataatag aatattgtct
     2641 taaatgctat attatgctaa aatttaattg tattttgtaa attaaaaaac ttataattta
     2701 gttttctagg gttccgcatt ttataatggt caggtccaag agaaaacgcg caattgttgt
     2761 gtacacggaa ggataaaagc ctgggagata tttaagaata tttctatagg cttttttatt
     2821 tttacatatt ttaaatttga ggaggttttc taatgaaaaa atttgttatt gaggatgcat
     2881 tttggaatct atttcctagt gcaaaaattg gagttgttat ttgtaatgat atagataact
     2941 ctataaaaga tgaagactat aagaaaataa ttttgaaggg agaagaagaa gcattaaaat
     3001 acttggagga ctcagaattt agcaacaacc aagtgattaa agtatggaga gaagcattta
     3061 aaaaatttaa aacgaaaaaa ggagcaaggt cttctattga agcattatta aaaagagttc
     3121 ataatggaaa taatatagga actattaacc ctttagtgga tatctacaat tttatctcat
     3181 taaaatatgc attaccttgt ggaggggagg atatagataa atttatagga gatattaggc
     3241 taactagagc aattggtaat gaggagttta tcccactagg gacagatgaa aattcatttc
     3301 catatgaagg agaaataatt tataaagatg atggtggagc aatttgtaga tgttggaatt
     3361 ggcgtgaagc agtgagaaca atgcttactg aagatactaa caatgccttt ttatgcattg
     3421 aattagtaga tgaaagtaga tttaaagaat ttgaaaatgc tttaaatgaa ttagctaaaa
     3481 tagttcaaga aaaattgggt gggaattgta aaatttcaat tttagatatt gataataaag
     3541 aggtatcagt ggattaatat ggaggtgctg ttgtaatgga ctattctagt tataaagata
     3601 cttatattta gggtaagaag gtctatttta gatataacga ttatcaaagg atataatata
     3661 gaaaataaaa atgtagaata taaaaagcct ttaaaataag aaaaaaatgt attttaaagg
     3721 cttttattat actctttttt atttgcataa ttaacaataa aaatatattg ttaattataa
     3781 tatttttatt gaaaaacgat ataatataat gtattatact atatataaaa tattttaaag
     3841 gagttggcat gatgtctaat aaacttataa aaaatttact aagtggtata ttacaaattt
     3901 tattttttct tttaggatta gtaattgttg caggaggatt taaaagtttt atgtacctct
     3961 gttttagtgg agaagcaact ctacaaggta ctatttatgg aatattaatg tttattttag
     4021 gtgtatcata ttttatcatt ataaaatcat tgatagaagt attaggtagt tctgaatata
     4081 gcctatttgt aaaagagaat gtaaaaagat ttaggattat tggatatctt ttgcttttaa
     4141 actctctaat tgagtttatt tcaacttttg gtactactgg aaaaggaatg agatttctag
     4201 atttaggatt tggattttat tttactgttc cagtatttgt atattttata acttctctta
     4261 tgagttttgt aattgcagat ggatttgtaa aggcaataaa gataaaagag gataatgatt
     4321 taactattta gatgtgacac tttaatatat aggagataaa taacccgaaa agagtgacta
     4381 actagtaatt taaaataaaa tatattaggg tataatacat aaactataat gctaaaatta
     4441 aaagattata atactaaaat ataattatgt tttaattaaa at
//
LOCUS       DAMJWC010000143         4453 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMJWC010000143 DAMJWC010000000
VERSION     DAMJWC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4453
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.148"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     misc_binding    77..311
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            361..1380
                     /gene="pheS"
                     /locus_tag="PC503_003600"
     CDS             361..1380
                     /gene="pheS"
                     /locus_tag="PC503_003600"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF2529549.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     gene            1397..3790
                     /locus_tag="PC503_003601"
     CDS             1397..3790
                     /locus_tag="PC503_003601"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF2529550.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            3815..4405
                     /gene="zapA"
                     /locus_tag="PC503_003602"
     CDS             3815..4405
                     /gene="zapA"
                     /locus_tag="PC503_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF2529551.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
BASE COUNT         1753 a          520 c          918 g         1262 t
ORIGIN      
        1 gtattggata tatattaaaa atagtcacat aatttgaatg gaaatgatat aatactaaaa
       61 taaacaatat aatattgtaa atgcaatgaa agaggaaagt attttgatta aacttagtaa
      121 agagataaac acctaggctg ggagtgtttt ctaagaggtc atgagaagtt ccctctggag
      181 taacagagct gaaattttac agtaggcttt gacgtcaaaa acgcgttaag tttgttagag
      241 gtggtttgat gatttttaaa ttgttaaact actagggtgg taccgcgaaa ctatagcctt
      301 tcgtccctag acagggattg aggggctttt tttatacaaa aaaacgaaag ggtgatatgt
      361 gtgcaagaaa aattacttgc tttacgtgaa gcagctttgg ctgaaataaa agaagcacaa
      421 agcatagaaa gtgtagaaag tttaagagtt aagtacttag gaaaaaaagg tgagataact
      481 gccatactta aagaaatggg taaattatct gctgaagaaa gaccagtagt tggtaaggtt
      541 gccaatgagg taagagaaaa cattgaactt agcataaatt ctaaaaaaga agaaataaat
      601 gctattgaaa aagaaagaaa attaaaagag gaagtgatag atgttactca accaggaaaa
      661 gttttaaagg ttgggaagaa gcatccaata actcaaatta tagatgaagt aacagatata
      721 tttatcggaa tgggattctc tatagcagaa gggccagaag ttgagactgt tgaaaacaac
      781 tttgacgcat taaacgctcc taaagaccat ccatcaagag atatgagcga tacattctat
      841 atcaatgatg gggtattact tagaactcaa acatctccag ttcaagtaag aactatgaga
      901 agtcaagagt taccaataaa agtaattgca ccaggtagat gttttaggtc agactcgcca
      961 gatgctacac actcaccaat gttccatcag atagaagggc ttgttgttgg aaaagatgtt
     1021 actatggcag aatttaaagg aactatggat atcttcgttg aaaaattgtt tggttctgat
     1081 atcaaaacta agtttagacc tcacaacttc ccatttacag aaccaagtgc agaggttgat
     1141 gttacttgtt tcaaatgtgg tggtaaaggt tgcccaatgt gtaaatatga aggttggata
     1201 gaaatattag gttcaggtat ggttcatcca aatgtgctta gaaattgtgg aatagaccca
     1261 gaagtttaca gtggatttgc atttggagtt ggggttgaaa gacttgcaat gcttaaatac
     1321 gaaatagatg atattagatt attattcgaa aatgatatga gattcttaaa tcaattttaa
     1381 ttaggagggt atgtagatgt tagtatcttt aaaatggctt agagactatg ttgatataga
     1441 catggatgta aaagagttcg ctgataaaat gacaatgaca ggaactaaag ttgaaacaat
     1501 agattattat ggtgaagaaa tagaaaatat attggttgga aagattttag aaataaaaca
     1561 acatccaaat gctgataagt tggttgtaac taaagtagat attggagata aagttgttca
     1621 aatagttaca ggagctacaa atatatcaga aggagattat attccagtag ctgtaaatgg
     1681 ttctaagtta cctggaggag ttgaaatcaa acagactgat ttcagaggtg aattatcaga
     1741 tggtatgatg tgttcagcag ctgaactagg tatagatgaa cattacattg aggagtataa
     1801 aagaggtggt atatatattt tagaccacga agattcttat gaattaggaa aagatataaa
     1861 agatgtttta ggattaaaag atgctttaat agattttgaa ttaacttcaa acagacctga
     1921 ttgtaaatgc atgatgggta tagctagaga agcagctgca actataggaa caaaagtaaa
     1981 atatcctgaa atcgaagtaa aagaaagtga cgaagagata gatttcaaag ttgagataga
     2041 taatccagat ttatgtagaa gatatgttgc tagaatggtt acagatgtaa aaatagaacc
     2101 ttctccatat tggatgcaaa gaagacttac agaagcagga gtaagaccta taagtaacat
     2161 agtcgatata acaaacttcg taatgttaga gcttggtcaa ccacttcatg cttttgatat
     2221 aaatcaagta gagactggaa gaatagtagt aagaaatgct aaagatggag agaaacttgt
     2281 aacattagat gatgttgaga gaacattaga caaagatatg ctagttataa caaatggaga
     2341 aaaatcactt ggtttagctg gtgtaatggg tggtgctaac tcagaaataa cttctaatac
     2401 gaagactgta ctttttgaaa gtgccaattt caaaccagaa aacataagaa tgacagctaa
     2461 aaaagttggt attaggtcag aagcatcttc aagaaatgaa aaagacttag accctaatct
     2521 tgcagagata gcagcaaata gagctgcaca acttgttgaa atgttaggag caggaaaagt
     2581 tttaaaaggt gttgtagatg tatatccaaa taaaccagaa cctaaaaaat tggtagtaaa
     2641 tcctcaaaga attaaccacc tattaggtgt agatgtacca atggagcagt ttgtaggaat
     2701 tttagaatca ttagagttta aatgtaattt ggtagctaat gataaattag aaatagatgt
     2761 accaagcttt agaacagata tggaacaaga agctgatgta tgggaagaaa tagctagaat
     2821 ttatggattt gagaatatac cttctgtaca attagaagga aatacgacag caggaattaa
     2881 aacttcaaaa caaaaattca tggatgcttt aaaagataat tcaactgctg taggattaaa
     2941 tgaaatatta acatattcat ttgtaagccc taagggagta gataagataa gagtaccaga
     3001 aggtaatgca aagagaaatt ttgttaaatt acttaaccca ttaggagaag aaacttctgt
     3061 aatgagaact actttaatac caaatatgtt agatgtttta tcaactaatg tatctcataa
     3121 aatagaagaa gtatctgcat ttgagtgtgg acatatattc atcccacaag attcagaatt
     3181 acctaaggaa gaaaatagaa tgtgtgtagg tatgtatggt aaagatgttg acttctttgc
     3241 actaaaagga actatagaaa ctatacttgt aaatgtcgga tttaaaggtt atgaaattga
     3301 acctcaagat aataatacta ccttccaccc tggtagatgt gctaaaatag tgtataataa
     3361 taaatatgta ggtacattag gtgaattgca tccagatgtt atagaaaact acaatctagg
     3421 tcaaagagtt tatgtcgctg aaatagatat tgactttgta tttgataatt ctgatagaac
     3481 aaagaattat gtgccattac caaaatatcc atctacatca agagatatag ctcttattgt
     3541 taaagatgat gtatttgtaa aacaaataga agatataata aaggaaaatg gtcaaggatt
     3601 agtagaaagc tacaagttat ttgatgttta caaaggttct caaatagaag ctggatacaa
     3661 gtcaattgca tattcaataa cttatagaag taaagataaa actctaacag atgaagatgt
     3721 agctaaggtg catgataaga tattaagtga attaagcgaa aaattaaatg ctaacttaag
     3781 atcaaattaa caactaatgt cgggggaggt taggatgaac aaagtaatgg ttaaaatcca
     3841 tggcgctgaa tatccaatgg ttggagacaa atcagagaag tttatgatta gtattgctga
     3901 ttttgtagac aaagaaatgg ataaaataac acgtcaaaac ccgaaattga gcttatcagt
     3961 tgctgcgata ttaactgcat taaatatatc agacctttta tttgaatgtt cagatgagaa
     4021 tgagaagttg attaaagcga atgaagaatt gagtaagaag gttggagcat ctaatgaaga
     4081 gcttcaatta gaaatcaaat ctttaaagct tacgatagca gaaaaagaag cagaaaatcg
     4141 tgaagctgaa actaagatga aagagttaat tgagattata gaaaataaaa agcaagaaat
     4201 attcgaactt agtaatacga cagaaggttc tagagcagag ttagatgctt ataaaaacaa
     4261 gattgaggag ttaagtactc aacttgaaga agcaaatgaa agagctacta tagctgaaaa
     4321 cttagcttct gagtttcaaa acaaagctta tgatttacag ttaaaatgta cagggttaaa
     4381 taatgatgca aaaaatgtgg aataaactaa aagatttgct gtctcttgtt ttttgagaca
     4441 gcttctttta atg
//
LOCUS       DAMJWC010000144         4361 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMJWC010000144 DAMJWC010000000
VERSION     DAMJWC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4361
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.149"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            178..1068
                     /locus_tag="PC503_003603"
     CDS             178..1068
                     /locus_tag="PC503_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2529552.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEIIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            1286..2572
                     /locus_tag="PC503_003604"
     CDS             1286..2572
                     /locus_tag="PC503_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2529553.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(2661..3104)
                     /locus_tag="PC503_003605"
     CDS             complement(2661..3104)
                     /locus_tag="PC503_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF2529554.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(3128..3922)
                     /locus_tag="PC503_003606"
     CDS             complement(3128..3922)
                     /locus_tag="PC503_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF2529555.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
BASE COUNT         1692 a          494 c          676 g         1499 t
ORIGIN      
        1 ataacttttt agctataatt attattgtta ttaattgaaa agatttatta gttacttgac
       61 atagtttaca cttttaatta tagtataaat tggaatattt agataattat tatttaatgt
      121 ataagctaag tttttaatta atatggtttt atacatttat atagaaaaga ggtacgtatg
      181 agtagcacaa tcaaatcaaa tcgaataaaa ggtataatgt ttataatagc atcagcgctt
      241 ggctttgcaa tgatgtctgc attcgtaaag ctagctggag atttaccaag ttttcaaaaa
      301 gtgttcttta gaaatctggt atcagctata atagcttttt ggcttatcat aaaacataaa
      361 ggaagtctaa ctggtaaaaa agaaaattta aaagtacttt tatataggtc aatatttgga
      421 actctaggag ttatatttaa ctactatgca attgacaagt tgatgctttc agatgctaat
      481 atgctaaata aaatgagtcc cttccttgta gtaatatttt gtgcaattgc tctaaaagaa
      541 aaaataaatg taaagcagat aggagctatt ataattgcat ttataggagc tttattcata
      601 ataaaaccaa catttagtgt agaaataatt ccatatcttg ggggaattgc aggagctgta
      661 tttgcagcaa tggcatatac ttgtttaaga gttcttggag atagagaaga ttactataca
      721 attgtatttt tcttttcagt tttttcatta gttactgtag ggccaattgc ttttgcagta
      781 tatgaaccaa tgacccttat gcaacttata tatctattac tagggggagt atttgcaagt
      841 ctaggtcaat ttggaataac tctagcatat aaatatgcac ctgctaagga aatctctata
      901 tttgactata gtaatataat cttttcagca attttaagta tattcttatt caatgtctat
      961 ccagatatgt taagtgttgt tggatattta atagtatttt cggcagcatt ttatatgttt
     1021 ttatacaata agaagttaga taaattagac aaagaaaaga agaagtaaac tagataaaag
     1081 tgtttttata atttgtattg aatatttaag tctttgtatt aaaattaaag aaaatttaat
     1141 taaaaatgtt tggtatatta acttataaca gcagttaaaa ttgaaaaatt ataactgctg
     1201 tttcttttat taaaaatatc caaatgtctg taaaaataga ctataataga gtagtataaa
     1261 taatataaag gggataaatt aaagtatgga aaaagtgaaa gttgctgtga ttggagcagg
     1321 taatagagga acgtatgcat atgctccata tatttatgaa aattctgatg tatgtgaaat
     1381 agttgctgta gcagaaccta aaaaaggaag acgagaacta tttacacaaa aatataacct
     1441 agatagtaaa aatgtatttg aaactttaga agactttttt aaacatgaca agatggcaga
     1501 tgcagtaata atagctacaa atgatgatag acattatgat gtagcaaaac tagctcttga
     1561 aaaaggttat catgtactat tagaaaagcc aatgtctaat agtttagatg gtctggtaca
     1621 tatagatgac ttgtgtgata agtataaaga taagattttt atgatttgcc atgtactgag
     1681 atattctcca ttttataata aattaaaaga aattgtagaa agcaaaaaat taggagagct
     1741 agttagtata caatataatg aaaatatagg atattggcat tttgcacata gctttactag
     1801 agggaattgg agaaatagca atgaaaccag ccctttaatt ttagcaaaga gttgtcatga
     1861 catggatatt ttgttatatt tagtaggaag tagatgcaaa aaaatatctg catttggaag
     1921 cttaaagcat cttaataacc aaaatgctag tggagagatg gcacaaaatt gtcttcagtg
     1981 tttagttgaa aaaaaatgtc catattcagc aaagagaatt tatttagaaa aagatagaag
     2041 tataaataga gctgttcaca taaatccaac tgaagagaat ctattaaata tacttaagac
     2101 aagtccatat ggaagatgtg tttacagatg tgataataat gttgtagaca atatggtaaa
     2161 tatactacag tttgaaaatg gagtgacggc tacttttaat ttatgtgcat ttactaaaga
     2221 aaatggaaga actataaagt taatgtttag ccatggtgaa gttggtgggg atttaaataa
     2281 aaatgagata agaattaaag aatttggaaa aaacgaagaa atagttatga atccatcaaa
     2341 tcaacagaat atggtagagg aatatgatag aaatcttata gctgaattta ttaaattagt
     2401 ttcaaataaa gaactagaaa agggtagagt agcagcaaaa gaagctatac aaagtcatgt
     2461 aatggcattt gcagcagaat attctagggt cagtgatgaa gtagtgtata tagaagaatt
     2521 ttttgatagt gctaagcaaa tgactaagga gatagaagaa actatatttt aattaataaa
     2581 aatttattaa ataaaataaa gatagattaa ataatagaaa tacgaaaata tgtgttctat
     2641 taaggaatct atctttttta ttaaggtttt ttcttatccc tatcaaaaaa atccatacat
     2701 tctgataaaa gataagaaag taaagcgaat aagatttctg tacttaaagg aatcgttact
     2761 gaatccataa aggtatcaat tatgttcata gctagaaaag ttagtataaa atcaattata
     2821 aattcgcaaa gtttatatat tgagtatggt aatttgttta catatctgaa tatatctaaa
     2881 atagtagtgc atagaaaatc aattggagtg gttatacaaa aatatattaa aaagaaaatt
     2941 aatacagctc caagagattt atattcaaat cctaagaatg ataagaagcc aattcctata
     3001 accgtgaaaa tacaaaaagt tataccaaaa aaaacagcaa aaaataaaaa tacagaaata
     3061 aattcgccta aaggaatcct tcttttatta cttatcttaa tcaactcctt aatttatgat
     3121 atgaaattta tataaataat aacattctta aaaattcata atagtcctct gtttcaaata
     3181 gtactgtttg agaatctatt tttttcatat ttggataaaa agaggcctta aaagctttat
     3241 aatgttctct aaattttatt tctatcttaa atttatctgg caattttatt aagtgcctag
     3301 ataaatctcc agataaagct tttttgacac ctttttcaat tttttttagt gcaaggtttg
     3361 gatggattga aattgaacca tttccaattc cttttgacac aggaacagtg actatatttg
     3421 gatttagttt ttttgcactc tcacaaagca tttcatctcc acttaaaaat gctacaggaa
     3481 cattataata tgcagcaata taagcattta tagtaaattc agatgctatt tcatcattta
     3541 ttttaaaata gtcataatca atatccatag tatgggaaag tggattacca ttacaagtag
     3601 ctccagagtg atagccggtg aatatacatg catcaaagct ttcatcaatt ccagccatca
     3661 taactagtgg gtctttggtc catcctctaa gtattttgac gttttcaggt aaaatatttg
     3721 gattaatatt tctaccactg tcatgtgcat ctttaacaag tatttcatgt acaccagatt
     3781 gagtagctcc atcacatgct gctgttatct ctttactcat ttgtgttcta tagtgttgcg
     3841 aaaattcaca ttcaagtttt gtttcatccc aatttacaat accacaagta ccttctatat
     3901 cagcacttaa atacaatttc ataatatata cccccttatg tttattattg atgataataa
     3961 cagataacag aaaatacata atcaataaag ggcataaaaa tattatgtct tactattaat
     4021 tattattaaa tctgtaactg aaaaataact aaattggtat taaaaaatat aacactatgt
     4081 gtcatttatt tatatagttt ttatatctga tgtttatata aaattgtaac atataagtgg
     4141 ttacatttac tagtttaaca tagttaaaat agttaggtat tatttttaag ttaaattgat
     4201 tattataaaa tcgcagaata aaagaaagat ttaatttatt aaaatgcatg aaatgttttt
     4261 tcctcaacat aatgctaaat taaactcaaa aagaaataat agaaaaatct tatgtagctt
     4321 agaaagaatg tgaatgattt aagggaaaaa tagaaattta t
//
LOCUS       DAMJWC010000145         4289 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMJWC010000145 DAMJWC010000000
VERSION     DAMJWC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.150"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            275..1894
                     /locus_tag="PC503_003607"
     CDS             275..1894
                     /locus_tag="PC503_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2529556.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            2268..2462
                     /locus_tag="PC503_003608"
     CDS             2268..2462
                     /locus_tag="PC503_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2529557.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(3021..3344)
                     /locus_tag="PC503_003609"
     CDS             complement(3021..3344)
                     /locus_tag="PC503_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529558.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(3389..3643)
                     /locus_tag="PC503_003610"
     CDS             complement(3389..3643)
                     /locus_tag="PC503_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529559.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(3907..4188)
                     /locus_tag="PC503_003611"
     CDS             complement(3907..4188)
                     /locus_tag="PC503_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529560.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT         1562 a          560 c          494 g         1673 t
ORIGIN      
        1 atatttttta caattatagt taattctttg ttaaattgat tgtacataaa atactaaaaa
       61 tctaagttca agtatttaaa ttgctatata tcataaattt tctaaaatta acaacaactt
      121 aaaaatttaa cattctctta acgtatactt aacaaaacat taatattttt attgacaaaa
      181 tttgttattc tatattatgg aaacaataaa ttttagttaa taaagtttat aattcagata
      241 aaaaaattat taatttctta agggaggaaa tatcgtgaat atagtaatta gccttatcgg
      301 tggacttgga ctttttcttt acggaatgag tttaatggga gaaggtttac aaaaatcagc
      361 aggagacaaa ttaaaaaaaa ttattgaact cttaacaagt aatgttgtta tgggtgtact
      421 ggtaggtaca gtcgttacag gtattataca aagttcaagt gctactactg ttatggttgt
      481 aggatttgta aatgcaggta taatgaatct aagtcaagct attggtgtaa taatgggggc
      541 aaatataggt actacagtta ctgctcaatt agtttcattt aatcttgaag gaattgcacc
      601 aattgcttta ggtataggta ttttattcta tttatttaca tcaaatcaaa aaacaaagca
      661 tttatctgag atacttatag gtttcggtat attatttaca ggaatggagt ttatgaaaga
      721 tgcagtagct ccacttgctg aatataaagc attcactgat gcacttttat attttagtaa
      781 aaatcctgta ttaggtatat tggcaggatt tgccataact ggtattgttc aaagttcaag
      841 tgcatctatg ggtatgttaa tagcactagc ttctcaagga atacttcctc tatcatctgc
      901 tttacctatt ctttatggag ataatatagg tacttgtgtt acttcacttt tatcaagtgt
      961 tggtgcaagt agaaatgctc gacgtgcagc tgtaatgcat ttaagtttta atgtaattgg
     1021 tacaataata tttatgcttg ttttaaataa acctatatca gccatagtta ctcattttga
     1081 cccaactgat acagctagac aaatagcaaa tgcacatact ttatttaatc ttacaaatgt
     1141 tataatatta ttaccatttt ctaaatacat agttaaatta gcaaatagac ttatacctat
     1201 taaagaaact gaatcagaaa tagtaaataa tactaagtac ttagatgaaa ggatgtttag
     1261 cactccatct atagcacttg gtaatactgt acaagaagtt gtaagaatgg gtcataaagc
     1321 tacaaactct ttggaacatt caattgcagg atttttaaat aagagcaatg aagatattaa
     1381 taaagctttt gagtcagaaa aagttgtcaa taagttacag aaagatatat tgaactattt
     1441 gttaaaactt tctaaagaac ctcttagaga tgatgaacgc tttagaacag atttgctttt
     1501 taatactgta aatgacattg aaagagtctc tgaccatgca gaaaatatag ctgaattggc
     1561 catgagtgtt aaggaaatga acattagttt ttctgatagt gcgataagag aaatatacga
     1621 aatatacaat aagacaatta ctaattttaa ggatgcctta atagttttag atgttaaaga
     1681 ttttgagtta gcaaataaag ttttagaagt tgaaaatgaa gtaaattatt tagaaaaaac
     1741 ttttagaaat tcacatatga ttagactaaa taatggaagt tgtacaattg atgctggtgt
     1801 actttatctt gacttactta ctaatctaga aagaatttct gaccactcaa caaatatagt
     1861 aaaacaagta ctaaaactta aacaaaaaat atagtgatta tttttatata taatcttaat
     1921 caatgagaag taagaagcta tagataatgc ttatatcatt tatggcttct tattttttat
     1981 gtaatactca aatttttata gtattctctt attattaaac agtttctgcc tagaatattc
     2041 catatatata tgacttcttt cataaaactt gaactgccca taaataaagt cacaagtata
     2101 cataactatt ttttaatcaa ttataaccaa tatttgtttt atttatcttc attttaattc
     2161 ttcattcaat aatgtaataa tattattttt tatttggata ctattatatc atctaaatat
     2221 gttattatat atttggatat tttcatatta ataggaggga ttctacaatg ataaattata
     2281 tggtagaaat tatatatagc gaaaaaataa gcgaagtaga aaacatgttg aaaattgaaa
     2341 atatacaata tgaatttact tctcgtgatg gctttatatt ttttggtttt tatgatatga
     2401 cagacgcata tagatttgag actttatgtt cagatgaaaa aattcgattt aaaagaatat
     2461 aatagataaa aaagtacata tttctaaact atttgttttt caaatttagg ttgtgtttta
     2521 atgtagtgtt gatattataa acaattttaa taataaaaaa gtagggacat tatattaata
     2581 tgctcctact ttttactcat acttattaat attatttatc aaaattaccc tacaaactgg
     2641 aatttatcat tctttcataa ttttaaacta tcatatttaa aatatataaa attctacatg
     2701 atttttgtat aaacataata tcaaccatta tccaatttaa aaatattttt tagtaatttc
     2761 catttcattt tctcttaaca tattaattaa acttttatat gtaaatggtg tatttacata
     2821 ttatttaata tccaacaatt atataaagaa atgtgctctt tgccttataa agaattataa
     2881 agccaattcg ttttattata ttatttttct ttatacctta aaaactttac cttcaaattc
     2941 ttatttatct atatattata aaaatgttct taacctcttt tacgagattt tcttgacata
     3001 ttatcagtta gataaaataa ttaaataata taatcagcaa gtatgttttt tactctttta
     3061 agtaaatttc cacctgcacc ccaatcaatt tttaaaattc caattgcact gcctgttgaa
     3121 gtagctttaa taactgtttt tcctgtggta ttttcataaa ctactattaa tcctgcatca
     3181 ctattatttc ttgcataata cttctcaaaa gttgtaatta gtataaattt atcatctcct
     3241 aaattataag aatcactaaa aactaaatct gcatcaagat tttcttttat cattttttgt
     3301 gcctctaagg gtgtaatttt tacagtaaat atttctgttg ccatttttta tctcctcata
     3361 agaatttatt ttagacaaaa cataatctct agtattttct gatatattta tcaaacaata
     3421 tccctattcc tcctaacaga gctaatatag aaccaaaatt tctatattga gaaatagatt
     3481 ggtctagata aatattatat tggtcagtat ccatgattcc accattttgt tgaataatat
     3541 gctctgcact aaattcacct aaacctatac aacagaataa tactactact ccaattacaa
     3601 aagcaaatat acatattgtt aatttaaaat ccttattttc catagttatc cctctcataa
     3661 gctaaattta tttgattatt tttactagat tttatattac tcttattata caatacaaca
     3721 tatatttaca tctatttcca aaattgtaac ctttatagtt ttatatattt aaatttttta
     3781 aacaaaaaat acacatctat aaattataaa tgtgtattct gtaccattac taataatata
     3841 ttatactttt ttacaaattt ctaattattt ataactattc aaaaataaaa ttcatataaa
     3901 ataattctat tgtacaattg aaactttaat aatgtctcca ttttttctct ccaagtgaac
     3961 tacttctcca gttaaatcat agtcaaatgc cttaactaat atttcagtaa cttttttacc
     4021 atctactaca tcatcttttc cattaaataa atccaaagca ttattctcaa tcattctctt
     4081 tgcaaaattt acaggtaact ttatatgtat tttatcgcct gtatgtgata agactcttat
     4141 tcttaaaaac ttttctaaat tgtttcttgg tatttgtttt gatgccatgc tattaaatca
     4201 ctctccttta ttttttattt aataataaat tttattctta aaaatatctt tatatgtatt
     4261 tattatgaaa gtaacactat tattttcta
//
LOCUS       DAMJWC010000146         4233 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMJWC010000146 DAMJWC010000000
VERSION     DAMJWC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4233
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.151"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(170..370)
                     /locus_tag="PC503_003612"
     CDS             complement(170..370)
                     /locus_tag="PC503_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529561.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(372..722)
                     /locus_tag="PC503_003613"
     CDS             complement(372..722)
                     /locus_tag="PC503_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF2529562.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            884..1072
                     /locus_tag="PC503_003614"
     CDS             884..1072
                     /locus_tag="PC503_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2529563.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGESELKIKKFSILYGSS"
     gene            complement(1549..1719)
                     /locus_tag="PC503_003615"
     CDS             complement(1549..1719)
                     /locus_tag="PC503_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529564.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(2108..2596)
                     /locus_tag="PC503_003616"
     CDS             complement(2108..2596)
                     /locus_tag="PC503_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2529565.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            3400..3774
                     /locus_tag="PC503_003617"
     CDS             3400..3774
                     /locus_tag="PC503_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2529566.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            3879..4233
                     /locus_tag="PC503_003618"
                     /pseudo
     CDS             3879..4233
                     /locus_tag="PC503_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         1746 a          488 c          503 g         1496 t
ORIGIN      
        1 attaataata caatagaatt agttatcatt caacatatct agttgaataa ttaataaatt
       61 tatatatgaa ctttaaatta tttgaaaaaa taaaaagccc ctctgtcagg agtgacttaa
      121 aaattgaatt taagtttgta tttaaaacac atttttaata atgcaaaaac taatcaaaaa
      181 taaacaattc atcaataggt gtatctacta tttttgatat atctattgct aatttcaaag
      241 aaggattata ctttcctgct tctaaacgca taatggtttc tcttctaact cctacttttt
      301 ctgctaattg ttcttgagtt aattctttta attgtctata tttttttagg ttacaagtga
      361 atttaggcat attatttttc ctctaaaata taaagtttta tagcataaac atttaaagtg
      421 attgcatatg taattgatag taaaacacac attaattcta tattcctaga cactatagta
      481 atacaccata aaatgaataa ttctataata gcaagctgtc ctgtaaatgc catagctgct
      541 ttttcatctt gtacatacct ttcatctgct ttatcaccat ttatttttgc tataataaag
      601 tttgagaaaa aagcaaaaaa tccaatatat gtaaggtcag caacattgcc agatgaaaaa
      661 tatctaagac ttaaaaatcc aaggaaacca caaaaaccca taaaaaattt tttctgaatc
      721 attttttatc ctccttagta attttaaaag agatatattt atatctttat gatacaaata
      781 tatctctttt atattctttt gtcaatagaa aatcagtatt atacaatatt tatactgcac
      841 cataattgtt agagcaaaaa tctaatgctt gagatgttta tgtatgacta aatatgattt
      901 taatttcaaa ttaaaagtag ctaaatttta tttgaataga gaaggaagag atattttaat
      961 agtaaaacaa tatggagttt atgaccattc tcaagttgaa agatgggtta atatattagg
     1021 agagagtgaa ctaaaaataa aaaaattttc tatactatat ggttcaagtt agatgttata
     1081 aactatatga tgataactaa atatagtgta caataaatcg ctaagtattt tggaataaac
     1141 aatagcacag ttatagcaac atgaaaataa aaatttttac atagtggtgt tgatgccttt
     1201 tctaaaatga aaggaagacc ataatgaata aaaacaaaaa cactaaagaa aaaataaatt
     1261 aacaagagaa caagaattag aatatgaaaa taaattttta aaagatgagc ttgagttttt
     1321 aaaaaagatg tgtgtctcag ggaagccaca ttaaaaaaca gtggtatcat tattaatcaa
     1381 aagaaagtta gatgtattat caaaaaatta gaacttaaat gcatagcatt ttttcataaa
     1441 tcacataaat ataactccta taaaggtata attggaaaag taaaaaataa taaaacaaat
     1501 agaagattta aaacatcaat agcatatcag aaaataacaa atgatatgct agaatttata
     1561 aaatatatct aatgataaaa atggaaaatc aattataaaa aaggcatatc tcgattcatt
     1621 ttttgttata tagtcaaata agaatactat agatgaaaga tacgattttg catatgtatt
     1681 aagtaagtat tctgatgttt ttggttgata cacatgcaat aaagaagttg tgtttgcaga
     1741 taaattagca aaactatagt ataagttgca acaataaaga aaatgaaaat tatcatacta
     1801 aagcataagg catgttacaa ttttattaga taggacatta acatacacta aagtactttt
     1861 tattataaag agtacttatt tttttgaaat tcattaatgt ataaactatc aagaatatta
     1921 ctcaacataa tttaaaaaca acttgaatag gtatttttaa attatgtgat ataataaaaa
     1981 atagaagtgt atgccaatac acttctgtag ttataactaa gcattctatt cttgaggagt
     2041 gcttttttca tttttataac caactctttt tactttaaca ataattatca gacctatata
     2101 tttattttta attgtctgat ttattagata aaaaagttat tatcatattt ttatcatttg
     2161 gtatttttat tgaactacca taatcttctt ctaatttatc tagaccactt ttacttattt
     2221 ctccatctat aattatgttt aattctaagt attcttcact accattagat gacactaaag
     2281 tgtacgaacc attataaggc atgcctaaat tttctatttt atgtgccaaa gggtcttcat
     2341 caccaatacc agagtttact gttatttttc catctttttt agtccaccat attatgtttc
     2401 cttcagtata ttttgattca tctgcatagt agctaagaga cgcacttttt attgcactta
     2461 tatcagcttc aagtttagct atctttgctt tttctatatt tttaaataat gctggaagtg
     2521 ctactattgc caatattcct attatagcaa ttactactaa taattccact agagtaaatc
     2581 cttttttatt tttcatttat ttcccctcca tataaaatta ataatatata aatttttatt
     2641 ttgttaattt ctactttcta tattttacca tatatagaca aaaaaatcac tttctatgac
     2701 aaatatacta ttattttaca atttatggaa atgatttaaa atgacatttc ttgttagaaa
     2761 agatataaga aatggattaa aataaagaaa actacagtca tatcaatgtc aataatatta
     2821 tttaaaagca gatgaaaata aaaagaggac tcagaaaata atgtctattt aattatactt
     2881 acttaccaat accataactt gatataaaca agattatact acattttttt atgctctagt
     2941 ataaaatcat ctaactgtgt atctataaaa tcaaaataat tatatgaact atcagtataa
     3001 taagtcaaaa tatgtataca tgaatacata ttttaaaaga tatatattat tacataccta
     3061 aaaaactttc ataaaaacaa aaataaaata tgcttttagt aacttgttaa cataacttat
     3121 aatttatttt ataagcatta gcctatatag ctttgtgcta ctaaatctct ttgattctaa
     3181 cgatttagtg ctattctaca actaaaataa tacaatagag ctatttattg tttggtagca
     3241 ttgtttgtaa attaaacaaa tttatacata tgaatattat tttacattca aaaaaacaga
     3301 ctaaatatgt agaatatttg gtaaaactta cctctagttt ttgtcttaaa aagctcctat
     3361 tattaactta agttagaaga attaaggaag tgacataaat tgaaagaaga aatattaata
     3421 gaaaaattat taagagcaga attaatagta atggagtatt tatggaaaaa agacactcta
     3481 atgcctaaaa aagaaattgt aaaagaaata aaacagattt atggatggca taaaagtaca
     3541 ataaaaatac tactaaaaag gctagttgct aaaaggtatt tggctagata tattataaat
     3601 tctcaatctc attataaaat aatagatagt aaagaatatt atacttttaa gaaaaaggta
     3661 ctaaaatcta gtaaaagcat aaaaataatg cgttcactta ccactacaca taaaaatgta
     3721 agtaaagaga agttagacct attagatgag tattatagaa acttaaaaga atgatatagt
     3781 aaaaatcgaa tgtaattatt taccttaatt cttttgtttg taaaacttta ttgatacaga
     3841 atttaacata tacataaatt ggtaaaggaa tgtatactat gaaaattagt aaattaccag
     3901 aagcggaatt aaaagttatg agatatattt gggaatcaga aaaggtatta atatcaagag
     3961 aaatcaccaa gtctatggaa caaaaatatg aatggaaaga tacaactata tttacagtat
     4021 taaaaagatt actaaagaag agagttttta gaagcggaga aaatagataa gtgtacacac
     4081 tataatgtat tagtaaaaaa aaataatatc agagatttta aacaaaagaa tttttaaaga
     4141 atacacataa aaattcaata ttaagtttaa tgtcagcact atgtagtaag gatgatgaag
     4201 tagatggtga tattttaaat ttattagaag aat
//
LOCUS       DAMJWC010000147         4101 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMJWC010000147 DAMJWC010000000
VERSION     DAMJWC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4101
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.152"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..2321)
                     /gene="carB"
                     /locus_tag="PC503_003619"
     CDS             complement(<1..2321)
                     /gene="carB"
                     /locus_tag="PC503_003619"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2529567.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIM"
     gene            complement(2514..3563)
                     /gene="carA"
                     /locus_tag="PC503_003620"
     CDS             complement(2514..3563)
                     /gene="carA"
                     /locus_tag="PC503_003620"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2529568.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(3820..>4101)
                     /locus_tag="PC503_003621"
     CDS             complement(3820..>4101)
                     /locus_tag="PC503_003621"
                     /inference="COORDINATES: protein motif:HMM:NF014225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529569.1"
                     /translation="NSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGND
                     STRDGFKIRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
BASE COUNT         1177 a          811 c          415 g         1698 t
ORIGIN      
        1 tccattatac caggtatcaa tatatcttct ttatcacata tagcatctac ttctatttct
       61 ctaccagtta gatatttatc tataagtact ggatttttat ggtctctatc aaatgcatca
      121 tccaaatact gaattagttt ttcttcgtta taagttattt ccataccttg accaccaagt
      181 acataagatg gtctaactaa tactggataa cctaactcct tagcaatttc aacaccttca
      241 ttagttgtcc atacaccttt tccttttggt ctatttatat ctagtctctc tagtaaatca
      301 tcaaattttt ctctatcttc tgctgcatct atatctctaa agtctgttcc cagtataggt
      361 atattttttt catgtaaaaa cttagccaat tttatagctg tttgtccacc aaactgtagt
      421 attacacctt ctggtttttc tttttctatt atatttaaaa cttcttcttc tgttaatggt
      481 tcaaaataca acttatcaga tgtatcaaaa tccgtactta cagtttcagg gttattgttt
      541 acaattatag tttctattcc catttttctt aaagatttta cacagtgaac tgaacaatag
      601 tcaaattcta ttccttgacc tattcttatt ggaccagaac ccaatactac aacttttctc
      661 ttatcactaa ctactacctc atcatattgt tcataagttg aatagtaata aggtgataga
      721 gcttcaaatt ctcctccaca tgtatcaacc attttataaa ctggttgtat attatataaa
      781 cttctcaatt catataattt ttctgggctt atcttcatta agtcagatat acctttatca
      841 gaaaatccct ttttctttaa ttcatgtaaa tattctttat ctaagtcttc tatttttaga
      901 acttttaact tttcttcttg ttctactatc catttaaatt tatttataaa ccacttatca
      961 acaccagtta tttctgatat catttctact ttatagcctc ttcttatcat ttcagctaag
     1021 tcaaatagtc tctcatcatc aggtactact actctagcct ttaattcttc taatgttcta
     1081 ccttctgatg gagcatgaac caatgaatat tttcctgttt caagtgatct tataccttta
     1141 agaatagcag cctcaaagtt acttcctata ctcatgattt caccagttgc catcatctta
     1201 gttcctaatt ttctattggc atgtctaaat ttatcaaatg gccactttgg tatttttact
     1261 accacataat ctaatgttgg ctcaaaacaa gcataagttt ttttagttac tgcattttct
     1321 atctcatcca aagtataacc taaagctatc ttagctgcta cttttgctat tgggtatcct
     1381 gtagcttttg atgctagggc tgatgaccta ctaactcttg ggtttatttc tattatcgca
     1441 tattctaaac tatgtgggtt taaagctatt tgaacgttac atccaccttg aacctctatt
     1501 gcatttatta tgtctattga tgcctttcta agtagttgat actcttcatc acttagagtt
     1561 tgacttggag caacaactat actgtctccc gtatgaactc caactgggtc tacattttcc
     1621 atattacata cagttataca gtttccattt ccatctctca ttacttcata ttctatttct
     1681 ttccaacctt ttatactctt ttcaagaaga acttgtccaa caggacttag ctgtagtcca
     1741 tgtgaaagta tttctcttaa ttcttcctca gtatcagcta tacctccacc agttccacct
     1801 agcgtatatg ctggtcttac aactactgga tatcctatct tattggcaaa ctcaagacct
     1861 gcttctaaat ttgtaactat atcactaact attactggtt gatttatttc tttcattact
     1921 tctctaaata aatctctatc ttcgcccttt tttatagatt ctatagatgt tcctataact
     1981 tttacattat atttatctaa tataccagca tcatgtaatt ctacagctaa gtttaatcct
     2041 gtctgaccac ccatacctgc aagtaaactg tctggtcttt ctttttctat tattttttct
     2101 ataaattcta ttgttaatgg ttctatatat attttatctg caatttcttt atcagtcatt
     2161 atagtagctg ggttactatt tactaataca acttcaattc cctcttcttt taatgcttgg
     2221 caggcctgtg ttcctgaata gtcaaactct gcagcttgac ctattattat tggccctgac
     2281 cctaatacta aagttttctt tatactatct aatttaggca taactctttc tccttatcta
     2341 aacaattttc acagttctta tcttcatcat ctatacaatc aactttaatt actttatttt
     2401 atcttaagtt caaatttact catcaataca tctatttaat acatctatgt taattaaacc
     2461 aaactttttg atttaagtta ttcttgtttt ttagttagct attctaatgt tgtttatttt
     2521 actaattcta aaaatttatc aaaaatatag tcattatctt ttggtcctgg gcaagcttca
     2581 ggatggtatt gaacactgta tacatctagc ttctcatgtc gcattccttc aacagtatta
     2641 tcatttaaat ttatatgtgt cactttcatt tgttcaggaa cttctgaaac ataataacca
     2701 tgattttgag aagttataaa tacttttcct tcttctaaat ctttaactgg atgatttcca
     2761 cctctatgcc caaatttaag tttagcagtt tttcctccaa gagctaaagc taaaagttga
     2821 tgtcctaagc atattccaac tataggtttt ttaccaataa gagcttttat attttctata
     2881 acatcttcta agtcttctgg gtctccaggt ccatttgaca agaatattaa gtcagggttt
     2941 atactcaata catcttctgg agatgttgta gctggaaata ttgttatatc acatccacga
     3001 gctataaatg atcttaatat atttcttttt actccaaaat ccataacagc cacttttgga
     3061 ccatttcctt ttatatgctc tacttctttt cttgtaacag ttctaactgc ttctgtattt
     3121 gaaaacttat ccaatttatg tttaacatct tctaatttac tgtcttctaa tgtaattata
     3181 cctttcattg ttccattatt tctaagtatc ttagtcaaag ctcttgtatc tattccttca
     3241 agtccgataa ctttattttg ctttaaatat tggtctatat caatttcaca tctaaaatta
     3301 cttggagaat cacttttctc ccttactatg aatcccttta cttgaacttt ttcagactct
     3361 gctgatgata aatttatacc ataatttcct acaagaggat aagtcatagt aactatttga
     3421 ccatagtaag aagggtctgt taaaacttca ccatatccta tcatcgaagt attaaatact
     3481 acttctccta cactttcttc taaatatcca aatgcctttc ctataaaaac tgttccatct
     3541 tctaatatta accttgcttt catactacag tacctcctat aattctcttt agacaaacta
     3601 aagaacatta actaaatata agcttttaaa tatctatatc tatttttcac ttttacattc
     3661 tagttttata cttatttaca tttatttttt atctttttct attatactac aaatttctta
     3721 aaaaaaagaa gttatctcaa aagtaaaaac tcctagaaaa aataacctct tttttttatt
     3781 taataattaa attcttaaac tatacaatca acttaatttc tattcagcta tattgtaaac
     3841 ttttaactca tctttattta aatgtttctt cttaacttct actaaagctt ttagtgtatc
     3901 caaagatgtc attatttcag tagaaaattc aatagctgtt cttcttatct taaatccatc
     3961 tcttgtagag tcatttcctt tagttggtgt atttattact atatcaactt gtttatttct
     4021 tatagcatct aatatgtttg gtctagattc ttctactcta tttactatat cagcctctat
     4081 tccattttct cttaagctat t
//
LOCUS       DAMJWC010000148         4094 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMJWC010000148 DAMJWC010000000
VERSION     DAMJWC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.153"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            24..422
                     /locus_tag="PC503_003622"
     CDS             24..422
                     /locus_tag="PC503_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2529570.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            410..1348
                     /locus_tag="PC503_003623"
     CDS             410..1348
                     /locus_tag="PC503_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2529571.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1732..1956)
                     /gene="secG"
                     /locus_tag="PC503_003624"
     CDS             complement(1732..1956)
                     /gene="secG"
                     /locus_tag="PC503_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF2529572.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2549..3841)
                     /gene="eno"
                     /locus_tag="PC503_003625"
     CDS             complement(2549..3841)
                     /gene="eno"
                     /locus_tag="PC503_003625"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF2529573.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1414 a          657 c          459 g         1564 t
ORIGIN      
        1 atataaaatc ttaaggagtt gccatgataa aaaaaataga acatgtggtc attactaata
       61 ataatataga aaattatatc aatttttata aaaaatttgg tttttcatct aaagaaatga
      121 gcaaaaatta taaacttaat gctagaaatg ttaagataaa tcttaacata aaaggttata
      181 aatttttacc ttatgttaaa aattcaaaag caagtagaga taacttatgt tttaaaataa
      241 acacaaatat tgatgagcca aaaaaatact tagaacaaaa tgagattcaa attaagagag
      301 gaattgtaga atgtacaggt gtctttggta atatgaaatc tatttatttg aaaaaaacta
      361 atggaaattt aattgaatta tcaaatcata gaatcacgga gagtaaacct tggaaaattt
      421 aatcctatca ataaatgttg ttcttccttt gtttctcaca atgtcacttg gatatgttct
      481 aaaaaaatta ggtctatttg atactcatac tttaaataaa atgaataatg tttgcttcaa
      541 gtctttcttg ccattattat tattttttaa tatatacaat acagatttag atggttctct
      601 taattttaag cttatggctg tagctgttat aattattttt tcaatcttct taatcttagt
      661 ctttattatt cctaaaattg aaaaagataa taagacaagg ggtgcattaa tacaaggtgt
      721 atttcgtagc aatttcgtta tatttggtat tcctgtgaca atttcactat ttggcgataa
      781 gagtattgga gtcacatctt tattaattgc agttattgta cctatgttta atgtattatc
      841 tgttgtaatt cttgaaattt ttagaggtgg caaagtaaat ataaaacata tgattaaaag
      901 cgtcttaaca aatccactca taatcgcctc ttttatagga ttgacaatgc taattttaaa
      961 tattaatata cctacatttt tacacaaaac tattggtgat atttctaaaa tagctactcc
     1021 tttatcactt ataattctag gcggctcttt tagtttttct gctataaagg ggcatataaa
     1081 acccattata ttgggcgtat gtggaaaact tatacttgta cctgctatat ttttaccaat
     1141 tagcattttt cttggattta gaaatgtaga attagcttca cttatgataa tgttatctgc
     1201 tccaactgca gtttcttcat ttacaatggc acaacagatg gattctgaca gtgaattagc
     1261 tggacaaatt gtagtattta cttctggatt ttctataatt acagtatttt taataatatt
     1321 tattttaaag cagaataatc ttatttaatg atatttgata acacaaattg gtattataag
     1381 aaacatatat aaaactgatt taatcgcgta aaaacatatt attatactat ttttactata
     1441 taatataact ttgtgtatat tatctcatta aacatggtga aagtagtgtt gctatatatt
     1501 ttttagtttg aagaaaatat ataaatacaa acaatatata aatacaaata ataaacgcca
     1561 ccaaatagtc aatctataaa ataaaaactg gactaatcat ataaaatcat tagtccagct
     1621 tttattttac gtacttttta tgttgatgta cttttattaa aaactaaatt taatttttaa
     1681 atgtctagca aatgcactaa ttaaataatg gccagttatt caacaatatc actacttctt
     1741 aactataagt aatgccaatg catttataaa aaataatact gctgttatct ttgtaactct
     1801 agcaagaaat gcttgttttc cttttggttt aaagtaagct tgacttcctt ctccaccaaa
     1861 ttctgaaggt aaagcattct tagaatcttg aggcattatg ctaattacta gtaaaatccc
     1921 tagtactact tgcacaccca ttaaaatgtt gctcattctt gcccctccta tctgtttatt
     1981 acttaaattt cattactctt tagtgtatca caataatata gccatttcaa gactattatg
     2041 ctataaataa catacaaaaa aatatattgt tactataata tattactata ttctcaatat
     2101 aaaaatgaat aaaacttaga agagaaaact atttaaatta atacataaat taacacttaa
     2161 aataatctac tctcattgta tatattataa atagccacca aaataaaaca atcattttaa
     2221 aatattgata taacttttaa tttcaacata atttaaaata aataatccac atttagcaat
     2281 aatacttcaa tgacaattat gattaaatca aaatatgtct tcacttttat tttttaataa
     2341 aaacctccta tgcaattaga taaaaatgag atagaaacat ttattcatat tttttctgaa
     2401 tctatgaata aaattaagta ataaaatata aaaaaggata agtgaattga aaaatcaatt
     2461 aacacttatc tcttttatat cttataagat gagcttaaat atcttatatt ctctcttcat
     2521 taatcttttt tagtaaccat tttaataact atttttttaa gttatagaaa gattttaatc
     2581 cacaatatct agcttgctct ccaaccattt cttctattct taataattgg ttgtacttag
     2641 caactctatc agttcttgat ggagcaccag tttttatttg accagcattt actgcaacag
     2701 ctaaatctgc tatagtagaa tcttcagttt ctcctgatct gtgagatata acagcagtat
     2761 atcctgctct cttagccatt tctatagcat ctaaagtttc agttattgta cctatttgat
     2821 taactttaac taatatagag ttagctactc cattttcaat tcctttttct aatctctctg
     2881 tgttagtaac aaataagtcg tcaccaacta attgtaattt atttcctaat ttttcagtta
     2941 ataatttcca tccatcccaa tcttcttcgt ctaaaccatc ttctatagtt attattggga
     3001 agttgtttga ccaatcttca tataaagcaa ccatttcagc agcagttaac tcttttcctt
     3061 ctcctgctaa aacgtatttt ttagtttctt tgttgtacat ttctgtagca gcaacgtcaa
     3121 gacctaacat aacgtcttca cctggcttat atccagcttt tgttatagct tcaactatta
     3181 attctaaagc ttctctgttt gaacctaagt ttggagcaaa tccaccttcg tcacctacac
     3241 cacaagctaa tcctttttct cctaaaactt tctttaacga atggaatact tctgctccca
     3301 ttcttaaacc ttctttgaaa caacaagctc ctactggtaa tatcataaat tcttgaacat
     3361 caacgttgtt atcagcatgc tctccaccgt ttaatatgtt catcattgga acaggtaatt
     3421 gtttagcatt tactccacct aggtattgga ataatggtaa acctatttca tcagcagctg
     3481 ctctagctac tgccattgaa acacctaata tagcattagc tcctaattta cctttgtttg
     3541 gagttccatc taattctatc atgattgcat ctatagctgg ttggtcaaat gcatccattc
     3601 cttctatttc aggtgctatt atttcattta cgttagcaac agctgtttct acaccttttc
     3661 ctaagtatct tcccttatct ccatctctta attcaacagc ttcaaaagct cctgtagatg
     3721 ctcctgatgg aactattgct cttcccattg ctccatcttc taatactact tcaacttcta
     3781 cagttggatt tcctcttgag tctaatactt ctctagcata tactaattca ataactgaca
     3841 tttgtatatc tcccttcgat tttctattag ttaaattttc atttactgta aacatccgtc
     3901 tactatttta atctactttc tatattatag tacataaagt tgcttttgaa aattaggtac
     3961 aaatttattt gatgggtaaa tttgtaaaag ttcctatttt tattttattt tttataatat
     4021 tttaatttat ataatataaa aaaacttgtc taaaatccaa aaccaatctt aaatacacaa
     4081 atattataac taga
//
LOCUS       DAMJWC010000149         3701 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMJWC010000149 DAMJWC010000000
VERSION     DAMJWC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.154"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            380..2191
                     /locus_tag="PC503_003626"
     CDS             380..2191
                     /locus_tag="PC503_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2529574.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVATVLSKTFNIKETCARICSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2279..2860)
                     /locus_tag="PC503_003627"
     CDS             complement(2279..2860)
                     /locus_tag="PC503_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529575.1"
                     /translation="MSYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDSSNFNY
                     TNYYMEFEAIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(3296..3502)
                     /locus_tag="PC503_003628"
     CDS             complement(3296..3502)
                     /locus_tag="PC503_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529576.1"
                     /translation="MNQSQEKDLEFIKNHWDLTIIEKERNVTRIIRYSLIILAIIAFF
                     LPTKIKFSIYIFISLFCWLMYLVL"
BASE COUNT         1400 a          371 c          508 g         1422 t
ORIGIN      
        1 aagagttaaa ttgtaggtaa atagtatttt aattatttat taaaatatag attatgtata
       61 tgccaaattt aaaaagagac ataaagacat tatacaaata tattattggg gtgatatttt
      121 gtaagaaaag aagtgatgca gtaaattaat tgagtaattt aaaaatgatt taatgataat
      181 gttgatgaat gtttaaaaag aaattttaga aaaacgtata ttgctgtttg tgttggaggt
      241 gatgaatttg tagaatttat agggtataaa tgattaaact atttaagata aatacatatc
      301 actgtaaaat attgataatc attttttata agagattgat tatttgcaaa ttatatatat
      361 tacaaatgag gtaacaataa tgaagaaaaa atatgatttt ttaatttatt ctgctatttg
      421 gctagttatt attattcttt ttatattttc tctatatcat agtatagagc atattaaaat
      481 tataagtcac actggtacta ttcgcagtga aactcaaaag gttgttaagc aagaattgaa
      541 taatgaaaga aatgatgact tgataaaacg actggataat attctgataa agctaagaac
      601 aggtaatgga gaaaatggat ttcaaagatg tgataataaa gaatttcaac aaaaactaaa
      661 tcaaatggat tctatgtggg aatctatgaa gaaagaaatt ataaaagtta gaaatggtgc
      721 ttcaggtgat aaattatata aattgagtga agagtattct gtgttgtcta atcaaattgt
      781 ttttatatct gaaaaacact ctaatgcaaa attgtattct tttgctactg cactatttat
      841 ttatcttata ttctcaacaa taagtctttt aatttgggaa tattataata aaaaaaggtt
      901 taaaagaata ttttatactg ataatttaac aaaaataaaa aatcaggttg catttgaaaa
      961 cagagcgatt gaaattttgc acaatgcatc taacaaagag tatgtactgc taaatattga
     1021 tattgacaat tttaaatata ttaatgatac acatggatat gaatatggag ataaagttct
     1081 aataatagtt gcaactgttc tttctaaaac ttttaatata aaagaaactt gtgcaagaat
     1141 ttgttcagat aattttgtaa tacttgcaaa atatagagat tctcttttag aggatattcg
     1201 ggaaatgcta actaatgcta taatctctga attagatatg aatgtaactc aaactatatc
     1261 ttattgtata ggagcttact tagttgaaat tgataattta ggttataaat ctatcaattc
     1321 tatgatggat aaggcaaata ttgcacacaa ggtaagtaaa acaagaggaa tttcctccac
     1381 agtatggtat aatgaaaatc tgttaaaaca gttacaaatg gaaaatagta tttataatta
     1441 tatgtataaa gcgatagaaa atgaagaatt tcatatgtat ttgcaaccta aatttcaaat
     1501 atcttcttta aatgttgtga gcgcagaagc tcttgtaaga tggttttctc cagaacttgg
     1561 ttttttatca ccagatgaat ttattccatt gtttgaaaaa agtggattta ttattgaatt
     1621 ggacttttat atgttaaaaa aagcgtgttc atttgtaaaa aaaacgttta tgaaaaaaaa
     1681 tcaatataca tatccgattg cagttaattt ttcaagggtt actatttacc aaaatagttt
     1741 ttatcaaagg tttttagata ctgttaaaga atatgaaatt ccttttaagt atatagagat
     1801 agaggtaact gaaagtgctt ttaatgaaat atctcaacca gttatttcaa ttttagagga
     1861 acttaaaaag ttaggatttt taatttctat ggatgatttt ggatcaggat actcttcatt
     1921 aagtctttta tgttctctat ctattaatgg attgaagtta gataaaagct tacttaaaga
     1981 aacatttaac cgggagaaag tatatagtat tattcagtgt attattgaaa tgtcacatcg
     2041 tataggcatg tctgttgtat gtgaaggtat tgaaactaaa aaagacttgg aatttttaaa
     2101 tacagttaaa tgtgatgtag gacaagggtt ttatttttct aaaccgatag aagaaaaaga
     2161 attttttaac aaatatgtaa ctaaaaaata atataattat ttttatcagt ctatacattg
     2221 agtcatttta tatctcgtta aatgactcaa tgcactgtta tgtattttaa aatataaatt
     2281 atttaaaacg ttttttatac ttatatagaa attcttctat attttttgat tgttctctta
     2341 tttcaactgc ttctatatct agtaaataaa gtatagaatc atttgtaagt tcaacatatt
     2401 caccatcttc tgaaccgagt gcatgtctct caatttttaa tcctttttct tcataatatt
     2461 tttttgtttc tatatataat gattctcgct tttgtatgta gtctttcact tcattatttg
     2521 gaaagttata tgaatccact aatgtttcgc catttataaa agttttctcg gtagcaactt
     2581 tttcatccca acaatggatt tcttcccaag taaaaaatat ctcagttcca tctggaatga
     2641 atgaaaacct ggtaataata tataaataat tattgaaatt tacttcataa tattcaggaa
     2701 tagcttcaaa ttccatatag taatttgtat aattaaagtt actactatct ttttttacaa
     2761 atggtatttt ctcaataaat ttatatattg attgttcatt tttaaaaatt cctatatcat
     2821 agcttctttc aaattgatta atttttaata aatatgacat atattctcct tatttgttga
     2881 aatataattt ttataactct actaatttta aacattttta aataaatatt tgtatatacc
     2941 ttatataata ttatagtaat tagttttaaa tcaatagaat agtatgtatt tatctaatgc
     3001 ggcaatataa tttaaagctg gtgttgtaga aaaactaaga gtgaatatag caaagagaag
     3061 caatagtatt ttaaactttg tctctcttat tttttgaaaa ctaacattaa aacataaggt
     3121 ataaataata ttatcatata aatgaaaaca aatttgaatt tttctctggt cgatgtatat
     3181 agtaagtttg ttgatatgag aaaaattatt attgataata tacatgcata gaaaggaaat
     3241 ggtatataat attttcttaa gtttcttttt taggcatttc tattggcatt ttaggctata
     3301 gtactaaata cattaaccaa caaaataatg aaataaatat atatatagaa aacttaattt
     3361 tcgtgggaag aaaaaaagca ataatagcaa gtattattag agaataacga ataatacgag
     3421 taacatttct ttctttttct atgatagtta aatcccagtg attttttata aattcaaggt
     3481 ctttttcttg actctgattc atttaatcat ctcctgttaa tagtataatt ttaaagctat
     3541 tactttgttt tattttaaca tatttataca ctaaagtgaa ttttatgatt agatttattt
     3601 aattatttct gaattaaaac ttattagaat tctctatttt gataatttca aactctattg
     3661 attgtatgat aattgaaact ataggatatg taggataaca a
//
LOCUS       DAMJWC010000150         3669 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMJWC010000150 DAMJWC010000000
VERSION     DAMJWC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.155"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            184..1764
                     /locus_tag="PC503_003629"
     CDS             184..1764
                     /locus_tag="PC503_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF2529577.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            1938..2384
                     /locus_tag="PC503_003630"
     CDS             1938..2384
                     /locus_tag="PC503_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF2529578.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            2405..3448
                     /locus_tag="PC503_003631"
     CDS             2405..3448
                     /locus_tag="PC503_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF2529579.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT         1477 a          336 c          693 g         1163 t
ORIGIN      
        1 ttaaattata tggtataata aattaaataa ttgttttaat tcaaaatttt ttgttatttt
       61 aaattatttc aaaactctta gttttagtga ttttatttat gatatttatg ggattaaaaa
      121 gatttcaata gatatttttg gtaagtattt aagaagtctt taactttata ggagtgataa
      181 tttatgctaa taggtacatc taaattaagc agaaatgttg atactgcatg tgtagaagaa
      241 gtagggattc caatgattgt attgatggaa aatgcggtta tatctgcaat gaaaaatatg
      301 gatatagaca tgtataatag ttatacagtt gtatgtggtg ttggaaataa tggaggagat
      361 ggtcttggaa tagcaagaca tctaaataca tatggaaaag aagtaaacgt atttttagta
      421 ggtaatcttg aaaaactaag tgaatgctct aaaataaatt acaatgtact tttaaatatg
      481 ggaattaata ttataaatat taataaaaat gatttaagtg aaaaaaatta tggagaggaa
      541 aatgaagtag ataaaattat taaagttgag aaacaaaata ttataaaaaa taaaaattta
      601 acaattttta aagatagagt atctaaaagt gatgttgtag tagatgctat atttgggact
      661 ggattaaaac gtgatataac tggtattttt aaagaagtta ttgacatagt aaacgataat
      721 agcaaaaata cgtattctat agatattcct tcaggtatag atagcgataa tggaaatgta
      781 ttaggaactt gtattagagc aaacaaaacg attagctttg agttttataa aagaggtttt
      841 ctaaactatg acactagcgc acttataggt gatgtagttg tagaaaagat aggtgttcca
      901 gattttatta caagaaaata ccatgatgaa gagttcataa ctgataagac ttttgtaaaa
      961 aataatatta gaagaagaga taagcatggt tttaaaagtg attttggaaa agtatctata
     1021 gttgcaggtt caaaaggatt ttatggtgca agtttcatag caactgaatc tgctgttaag
     1081 agtgggagtg gacttgtaac attaattagt agtgaagatg tgcaagaaaa ggtatctatt
     1141 agacttacag aagcaatgac tttaaatttt gaagaagaaa gattaaataa attacttaat
     1201 tctagtgatg caattggttt tggtccaggt atgggagata atagtcaaac atttgataaa
     1261 ttacttaaga tagtagaaaa ttctaattgc ccaatagtat tagatgcaga tggattgaac
     1321 gttatgaagg acagatgtta taagttttta gaatggaaaa atagatttgt aattacacct
     1381 catttgggag aaatggccag gttgacagga gattcaattg ggtatataag agaacataga
     1441 gtagatgttg caaaagaatt tgctcaaaaa tataatctgg tggtgctttt aaaaggttat
     1501 caaactgtca taacagatgg taaaaaaaca tatataaatc ctacaggaaa tagctgtatg
     1561 gcaactggtg gaatgggtga ttgtttgctt ggaatgatta cttcatttat aggtcaaggt
     1621 atggatatat tggaagctac agttagtgga gcatatatac atggctatat aggagataaa
     1681 ttgagcaaag caatgtatac ggtaaatgct acggatttaa taagtaacat ttcattaaca
     1741 atgaaagagt tgttggatat ataattggtg atatttgata ctactttgta acaattttaa
     1801 caaagtatgt tgatataata ctattaatta attaatttat tttattgttt tgtaatttaa
     1861 atttatattc aaaaacattg tataaacata taatttatat agggttttat aattcatatg
     1921 aaaagagggt agatagtatg aagctaatat ggttgatagt agcagtctta tttggaatag
     1981 cagaaatgtt aacaccaagc ttaacattga tatggtttag tgtaggagct gtaatactta
     2041 tatttttaag tagctttata gagagtattt tcttacaaat tttaatattt gcagtaattt
     2101 ctatagcaat gttagtcgta gctactaaaa aaatagtaaa aaaagataaa ggctataaat
     2161 ctaacactaa tttacaagca atgatgtcta aaaaaggtat tgttacagaa gagatttctc
     2221 caaataacac aggtctagtt gtagttgaac atgaaacatg gacggctatt tctatagatg
     2281 gtgaaaagat agaaaaaggt tctacagtag aagtattaaa aattgaaggg gtaaaattag
     2341 ttgttaaaaa agtagacgcc acagttaatg tgacaaacca atagaataaa ggaggattta
     2401 tagtatgggt actaaaattg ttttaagtat tgtattaata gtagtagtcg tagcaataag
     2461 tttaacttgt ataagagtta taaaacaatc taaagtaggt ataataatga gacttggtaa
     2521 gtttcaaaaa gtggctgaaa caggtgtaca tttcttaata ccatttttag ataaaatggc
     2581 atatgtaatt gaccttagag aaattgtaat agattttcca cctcaaccag ttataactaa
     2641 agataatgta actatgcaga ttgatacagt tgtatattat aaagttacag acccagttag
     2701 atatgtgttt gagatagcta atccaatagc tgctattgaa aatttaacag ctacaacact
     2761 aagaaatata attggtgaac ttgatttaga tgaaacatta acatcaagag atataataaa
     2821 tgtaaaaatg agaactattc ttgatgaagc aacagataaa tggggtataa aagtaaatag
     2881 agtagagtta aaaaatataa tgcctcctca ggatattcaa gttgcaatgg aaaaacaaat
     2941 gagagcagaa agagaaagaa gagaggcaat acttcaagca gaaggtaata agtcagctgc
     3001 aatacttcaa gctgaaggtg aaaaacaatc tgctatatta acagcagaag ccaaaaaaga
     3061 agctatggta cgtgtagcag aaggtgaaaa agaatctgct atattagtgg cagaaggtga
     3121 agctgaagct ataagacaga cagctattgc taaggcacaa ggtgaagctg aaatgataaa
     3181 aagaactcaa atggcaacag cagaaggttt aaaattagtt ttttcagcaa tgaaagaggc
     3241 tgatatagac aataatattc tagcattaaa atctatggaa gctcttgaaa aaatggctga
     3301 aggtaagtca acaaaactgg ttttaccttc agaagcagtt aatttcctag gaacattcaa
     3361 aggaataaag gaagttatga gtgatgataa caaagaagta cttgatataa aagaagtttt
     3421 aaatgataat gaatcattaa aaaaataaaa gagttttgtt atcataggaa ggatatggaa
     3481 attaaaggtc gaattaatta aatatagcac aaaaatgcac gttgaaaaga agaggactta
     3541 taaattttta agtcttcttc tttgttttta ttagaaagat gaaattataa aaataaatta
     3601 acagaatttt tatacaattt atcctttact aatgtaaaaa gtgttatata atattatata
     3661 aaacatata
//
LOCUS       DAMJWC010000151         3655 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMJWC010000151 DAMJWC010000000
VERSION     DAMJWC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.156"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            245..1621
                     /locus_tag="PC503_003632"
     CDS             245..1621
                     /locus_tag="PC503_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF2529580.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1932..2603
                     /locus_tag="PC503_003633"
     CDS             1932..2603
                     /locus_tag="PC503_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF2529581.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2792..3589
                     /locus_tag="PC503_003634"
     CDS             2792..3589
                     /locus_tag="PC503_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF2529582.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1378 a          408 c          682 g         1187 t
ORIGIN      
        1 gtaaaagcta tgatagtttt agacctatta tatgtaaaaa atatagatgt ttttggtgca
       61 atttaaatta aaagatatat ataaaaattt aaaatattcc aaacagaaat tataaaaatt
      121 actatcattg tctttataca atatttatac tataatagaa taataattta gaggaaagct
      181 ctaaaaataa acaaattaag ggtcttaaca gtagtgattt tatgttaagg aggtataaag
      241 aaagttgaaa acaatagtta gaagacttat tctctacgca gatggaatgc gtcctactca
      301 aataatggta tctgggtttg ctgcgattat tgtaatcgga gcattgttgt taacactccc
      361 gatagcgtcg cagagtggag agagtatagg cttattaaat gctctattta cggctacttc
      421 agcggtttgt gttactggtc tagttatggt agatacagca acttattgga gtttatttgg
      481 acagatagtt ataataacat tgatacaaat tggtggtctt ggatttatga ccgtagccac
      541 aatgttttca cttatggcac gaaaaaaaat acaactaaga gaaagattat taatacaaga
      601 gtcattaaat caagctgatt tatcgggact tgtaagactt acaagatttg tattaataat
      661 aaccataaca atagagggaa taggtgcact ggttttatca actgtcttta ttccacaatt
      721 tggtttgtct aaagggatat ggtatagtgt atttcacgca atatcagcgt tttgtaatgc
      781 cggatttgac ttgatgggca gtgtaagtgg cccatttaca tcgttaaatt cttatgtaaa
      841 caactttaca gtatcaatga ctgtttgcgc acttatagtg cttggagggc taggattccc
      901 tgttgtactt gatattgtaa gaaaaagaag attttcaaaa ttaaatgtgc attctaaggt
      961 tgtattgttt tcaactgcta cacttatttt tgtgggtgca ttatttattt ttcttataga
     1021 atttaatcaa aaagctacta tggcggactt gcctttaaag ggaaaagtac tatcagcaat
     1081 atttcaatca gtaacagcaa gaactgctgg ttttaatacg cttgatttag ctactttacg
     1141 agaaagtagt gtatttgtaa tgataatttt gatgtttatt ggagcatcac ctgcatcaac
     1201 tggtgggggt ataaaaacaa caacactagc tgttttaatc attacagtta gaagttttct
     1261 atcaggaaaa tcagatatag aagcttttga aagaagatta gctccatcaa ctataaaaaa
     1321 atctcttggt atatttgtaa tcagtatatc agcagttatt tttggaacat tgattatttc
     1381 aataactcag cctaatttta cattagttca atcagctttt gaggttacat cagcacttgc
     1441 tacagttggt tcaagtttag ctggaactcc aaacttaaat gctttaggta agattataat
     1501 aataatcttt atgtttatgg gtagagttgg ttctcttact ttatttatgg ctatactttc
     1561 tggtggtaga agaaagagtc aaccaatcag atatgcagaa ggtaaaatta tggttggtta
     1621 agttaccaag gagtagtata aatttataat gggtttagag tagcactgta aatctgttga
     1681 taaaataaat gagcctagat gtaattatat gaagaaataa aatcaactaa tgaacaaaat
     1741 taattaatga aataaaaaaa cagggaaata aaatacaaat aaaaaggtaa atcaaaatta
     1801 aattaatctg tgtgtataaa attatatatt gtgtataagt tttgtatgtg taaagtatat
     1861 aagttttgta tgtgtaaaca attaatttaa gagatattat ataaattgtg tattagggag
     1921 gaagtttcga gatgaagcaa tatatagtca ttgggtgtgg gagatttgga agttcagttg
     1981 cgtctactat gcatctttta ggacatcaag taatggcaat agacaaaaat gaagattcag
     2041 ttcaaagtat atctgacaag gtaacccatt cacttatagt ggatgttact gatgagcaag
     2101 cgttaaggtc attaggttta ggtaactttg atgtagcagt agttgcaata ggttctgata
     2161 taagggcatc tataatggcg actcttatag ccaaagaaat gggtgtagag ttgataatat
     2221 gtaaggcaaa ggatgaatta caagctaaag ttctttataa aattggtgca gatagagttg
     2281 tatttccaga aagagatatg ggagtaagag ttgcacacaa tttagtttcg gataatatat
     2341 tagaccatat tgaacttgac ccagagtatt caattgttga aatcgtaact ccaaatagtt
     2401 gggttggcaa gacacttata gagcttgaat taagagctag atatgagata actgtacttg
     2461 ctataaaaac aggtaaaaat ataaatgtta caccttctcc agatgaggaa cttacagccg
     2521 gaagtatcct agttataatc ggtcaaaata ctagtataac agcgataaca tctggaaata
     2581 aggggataat tagaagaaga taatttacta tttaatatat atttaattgc aatgaaagca
     2641 gatagtatca tataattatg aatagttata tgatactatt tttttaatcg aaggtagtat
     2701 ttatttgtaa gattagataa agagaagtta aattaaaagt aaggaggctg tgctaatata
     2761 aaaatttata agttattagc atttagataa aatgattaca aatataaaca gtaaggataa
     2821 tgaaaagtta aagtatacaa gagcactatt aaaatcaaag aataggaata aagagtcaaa
     2881 gttcataata gaaggataca gaatagtaat gcttgcactt gaatgtatgg caaaccttga
     2941 ttatgtattt atcaatgaag aatttgaaaa taagaaagaa catgtaaaac tattagaaga
     3001 tttggataaa aaaaacacaa agatatacaa gactactaat aaaaacttta aagaattagt
     3061 ggatacagaa aatactcaag gaataatagg tgtagtttca tttaagaaaa aaaaattaag
     3121 tgaaagtata aataaaaaag ataaatttgt attgatttta gacagaatac aagacccagg
     3181 aaatatgggg actataataa ggactgctga ttctgctgga gtagatgcca taatagcact
     3241 aaagggatgt gtcgatatat acaacccaaa agtaattagg tctactatgg gttctatttt
     3301 tgatatgaat ataattgatg cttcacaaga tgaaactgtg gacatgctta aatcattgga
     3361 ttttaatata gtttcaagtt acttaaatac agaaaatttt tatgacaaaa tagattatgg
     3421 ctcaaaagta gcattggtga taggaaacga agcaaatgga ataaatgaag aacttgtatc
     3481 aaagtctgat attttggtta agatacctat atatggtaaa gccgagtcgt taaatgctgc
     3541 gataagctct gctatactga tgtatgaaat aaaaaaatac ttaatttaat gtattgtaat
     3601 aaatataatg tcatgttata atcttgaatt aaatagtaga gtatcaaaaa tagtc
//
LOCUS       DAMJWC010000152         3285 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMJWC010000152 DAMJWC010000000
VERSION     DAMJWC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.157"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            76..687
                     /locus_tag="PC503_003635"
     CDS             76..687
                     /locus_tag="PC503_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF2529583.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            985..1323
                     /locus_tag="PC503_003636"
     CDS             985..1323
                     /locus_tag="PC503_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2529584.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1730..3166)
                     /gene="miaB"
                     /locus_tag="PC503_003637"
     CDS             complement(1730..3166)
                     /gene="miaB"
                     /locus_tag="PC503_003637"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF2529585.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1137 a          475 c          372 g         1301 t
ORIGIN      
        1 agataaatca taattatata ttattgttaa aactcaatta tataattttt aataatatta
       61 ttttaggagg taaaaatgat aaacgatatt aaaaataaat tcaaaaatta caaaccatat
      121 ataaatggat acaagaatat gaagagagca tctgttttaa ttccaatagt agaaataaat
      181 aacacacact atatattatt tgaagttcgc tcaaaaaatt tgaagcatca acctagcgaa
      241 atttcttttc caggtggtaa aatagaatca ggtgagactc catatgaagc tgttattaga
      301 gaaacttgtg aggaacttgg aacttttagt gacaatatag aagtaatatc aagtcttgac
      361 ctccttataa caccagtaaa gtttatcata catccatact taggatatat aaaaaatatt
      421 aataatttaa atataaacaa ggatgaagtt gaccatactt ttttggttcc tataaaatat
      481 cttttagaga atcctccaaa tacttatagt aatactgtaa aagtttttcc agatgaaaat
      541 ctaccatatg gttcaattcc aaaccaaaaa gattataaat ttgaaagtgg aagttatcct
      601 attctgtttt ataaatataa agattatgta atttggggaa tgacagcaaa aatactagaa
      661 aactttttaa attttttatc agaataacac tcataataaa ttatcaaaat ttttacataa
      721 gaaatttata aaagtttcta aatttaacaa ttctaaaata tcaataacta tattttgtag
      781 cactttttta ttttattatt gtttgaatat ttgatggttt tcaatgcaat ttcaacataa
      841 atactatata ttagtgtata ctgttgatga attaaagtat gataatctat ttaataaagt
      901 atgaagtaaa tgattttaat gtgcctttat ggtaaaatta ctaataagta ataaaattaa
      961 ttaaaatata tggaggtcct tataatgttt gctgtaggat ttgttgttat aattgcactt
     1021 gcctttttca ttttaagtgt actattattt aatggaaaag ccagtatgct actagcaggt
     1081 tataactcta tgagtaagaa agaaaaagca cgatacgata aaaaaaaatt atgtagaagt
     1141 tctagcattg ttacttttat tgtctctata atgctattta ttatggcgtt tttgggatat
     1201 agaatagaga gtggtcaaat ggacgaaaaa aaaatggttc ccttttctat aatatttata
     1261 atagtcatac tttccagtgt attttttaat atcctctact ctaacaaaaa atgtaaaaaa
     1321 taaatagttg taagttgagc agttaattat aaaagattga ctgctttttc atgtatattg
     1381 actactctta ttaaatattt taacatttaa aaatctatgt aaaaataatg aatatagtac
     1441 aaacttctaa taatgatttt acctttgtgg ttacagtcca ctatatataa tttaatatga
     1501 taacagggaa ttattaatga caactaagta aacttttata aaatataata aaacaaaaat
     1561 agatgtacaa tgaaattata tcttatatca aatttatttt tattaatagc aaaaacttac
     1621 attagcataa catatgacaa attcgcttaa aataaaaatt tttaatataa tttgttctat
     1681 agtacatcta ttttgattag tttacataat tttattattt tgtacaatat taattattta
     1741 ctaatatccc atttaatgaa aaagttctag gttcagtaat tttgaccata actaatttac
     1801 caattaaatc atcatttcca ccttcgaaat ttacgagttt attttgtcta gttctaccag
     1861 caaacttatt ttcattattt ttacttcttc cttcaactag aacttcaact attctatctt
     1921 tatatccatc atttatttct gcagaaatcc tatttacagc ttctaacacc ctattaaatc
     1981 tatcatgctt tatatcttct ggtatttgat tttccatttt agcagcagga gttccctgtc
     2041 ttttagaata aataaatgta aaagctgaat catatctaac tttttcaacc acatctaaag
     2101 tgtccaataa atcttcttct gtttctcctg ggaaaccaat cattaagtct gtagaaaaag
     2161 caatacctgg aacttccttt ttagcttttt ctattatttc taaataatat tcctttgtat
     2221 aatgtctatt catttttttc aaaaggctac tgcttccgca ttgtattggt agatgtaaaa
     2281 actcacacac cttatcacaa tctctaattg cgtatattac ttcatcagat atatcttttg
     2341 gatgagatgt cataaatcga accctttcaa ttccttctat atcattcact tttcttaaaa
     2401 gttctgagaa tgaaactgga ttttcaagtg tcttaccata agaatctaca ttttgtccaa
     2461 gtaaagtgat ttctttcgtt ccatttgcaa caagctcttt tatctcgtta attatatctt
     2521 caggagttct acttctttct cttcctcttg tgtatgggac tatacaatat gtgcagaaat
     2581 tattgcatcc atacattata tttacaaatg cttttaattc aaattttcta ttacttctaa
     2641 gaccttctat tacttctcca tccacatccc atacatccac taacattttg tcagaattta
     2701 ttgattctgt aagtaattgc ggaaatttat atagattatg tgttccaaat ataaggtcta
     2761 catgtttata tttttttctt aattcctcta caacatgtgg ttgttgcatc atacatccac
     2821 atacagctat tttcatatct ggattttttc cttttagatg ttttaattgt cctaagttac
     2881 catatacttt tagctctgca ttttctctaa ctgcacaggt gttatatatt attaaatcac
     2941 tttcttcaac catcattgac atttggtatc ccatctcttc taacattgaa cataattttt
     3001 ctgaatcatg ttcattcatt tgacacccaa aggtttgagt aaacacgagt tttctctttc
     3061 cagttctgtt gaagtattct tcattttgtc tgtgtatttg ttctatatat ttatcttgtt
     3121 cttgtatttt ctctataggt attgttactt gttttctttt gctcacgtct attcctccta
     3181 gttaatttct tatattacac ataaccttaa ttatatcaaa taagaaaaat cttttaaaga
     3241 tattattatt tttctagttg tgttttaata gtaaatctaa tgatt
//
LOCUS       DAMJWC010000153         3145 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMJWC010000153 DAMJWC010000000
VERSION     DAMJWC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.158"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            81..623
                     /locus_tag="PC503_003638"
     CDS             81..623
                     /locus_tag="PC503_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529586.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            637..3129
                     /locus_tag="PC503_003639"
     CDS             637..3129
                     /locus_tag="PC503_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2529587.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRTMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
BASE COUNT         1279 a          400 c          498 g          968 t
ORIGIN      
        1 tagcttacat attgattaat aaattttaaa ggagtataat aaacagtgtt cataataatt
       61 ttaataaaag aggtggtaat atgccaaaga ttttagaaaa tgtaaaagaa gatatattaa
      121 aagtgtctcg ggatatgatt ttagaagaag attactcgaa tattagcata aggaaaatag
      181 ctcaaaggtg tggtataagt gcaggtacag tgtataatta ctttaattca aaacaagaaa
      241 taatagaata tatcacaaaa tctgaatggg atttattgat aaggcgaatt gaatactcca
      301 ataaaaacac tgaagattac ataaaaaaac taaacattat ttttactgaa ataagaaatt
      361 ttataaacaa agttcataat atccaataca atgacttttt aaacactttt gaaacagaga
      421 gattttttga aatgaaaaaa cacaaagacg actttcatga acagctttca aataaagtat
      481 atgaagcttt agaaaaagaa agttttttta ataatgacaa attagtatgc aatatcataa
      541 taaaaatgtt tttttcatat tcaacatatc ttcatataga atttgaagat ttaaaaccct
      601 atattgaaaa attaatacat taaggtggtg tttaccttga atcataatac tagtattaag
      661 aacaaggaca gtaatccaaa aatattttta gtacttacgc tttatctatt aggtatattt
      721 atgggagcta ttgatactgg aatagtatca ccagcaagaa cgattataca aaatagcctt
      781 ggagtaaatg aaaaaacggg aatttggatg attaccatat acacattaac atacgcttct
      841 gtaattccta tctctggaaa attagcagat aaaataggaa gaaaatatgt gtatctagtt
      901 agtatatttc tatttggtag tggttcatta atatgtggat tatcatcact attttccaat
      961 ttctatattt tattaattgg tcgtgttatt caagcaattg gtggtggtgg aatcatgcca
     1021 attgctacag cagaatttgg aactaccttc ccagaaaata aaagaggcat ggctttaggt
     1081 ttagttgggg caacatatgg tattgccaat attttaggtt caagcattgg tagcacaatt
     1141 ctaagtatct ttggaactca aaattggaag tggctatttt ttgtaaatct tccaatttgt
     1201 ttaatcatac ttattggtgg agttttctgt attaaaaaca ataagtctga atctaaagaa
     1261 aaaatagata agcttggtac attgatgttg atatgtataa tcgtatcact attatatggt
     1321 cttatgaata tagacttttt taattttaaa aattctatac aagatatatc agtttatcca
     1381 tacttattga catttattgt acttatacct attttcatat ttattgaaaa tagagctaaa
     1441 gaccctattt taagctttga atatttttta aatccgagaa tattgatagt acttatttta
     1501 tctttaattg ttggtattgg aatgatgggt atggtattcg ttccacagta tgctgaaaat
     1561 gcattaaaga taaatgctgg ttctggggga tattttgtag ctatattggg attatttgca
     1621 ggtattgctg ctcctttaag cggaagactt attgacaagt ttggggcaaa aaaaatacta
     1681 ttactaggat tttctgtatc tatgataggc tctctttacc tagttttaat tgctctaaaa
     1741 accaatactg tatttagtgt atgtgtaagt ttaatattta tgggattagg aatgggattt
     1801 actatgggaa ctcctctaaa ctatatgatg ttatcaaata caagattaga agaatctaat
     1861 tcagcacttg caacattatc cttgatacgc tcaattggta cttcaatttc tccagctata
     1921 atgattggat ttatagcaca tgcaggatta tctgtgcaag ataatattat ggacttagtt
     1981 ggaaagccct caactcctaa aatagttcaa cttgaagaac ttgaaaacat gatagatgac
     2041 ttaaaatcag accctgaaat ggcaaaaaat ttaaaaaatg tctctatccc aaatatgaat
     2101 gatacttcaa atataaatat ggacatgaca ggtggcaaac ttccaaaatc cttacttaat
     2161 aaagttcagt cagcagatac aaccaacatt accaatataa caaaagaaat atcaacaaca
     2221 atgtttgatg aaaaagttcc atctataatt actaaaatac agaaaaatgt acaaaaagga
     2281 atagatggaa cacaaagtgg aataaacggt attgaagatg gtgaaaataa actaaatagt
     2341 ggtattaaag gagttcaaac tggtattgac aatatggtaa aagctagagc tggtattaat
     2401 caaggaatag atggtgtaaa aaaaggtatt gctggtgttg ataaaggtat aaaaggtatg
     2461 gaacaaggtc ttgaaaaaca agatgaggcc atcaaggaac ttacaactgc ttataataaa
     2521 atacctacta cagaaaaaac tcctactgat aacgaaaata actcaaatga acaaaaccag
     2581 agtaatacca gtaattctga atcagacgac actaagaatg attctacaga aaataagaat
     2641 aacaattcca gcgagaataa accaaatgta aatgaacaaa aagaaagttt aaatgctcaa
     2701 atacagcaac taaaaaagac aagagatgac ttaaatacaa agttacaaaa aaataaaact
     2761 caaaagaacg aattaagtaa aaaactaaga acaatggaat ctcaaaagaa agagctacaa
     2821 agcaagttaa ataattctat aagccaaaag aaagacatgg aaaaaagcct tgatacaatg
     2881 caacagcaaa aaaaatcact ccaagcagtt ttagcaaaga cacaagaggt aaaaactgaa
     2941 ataccaaagg cttttgataa atcaaaattg gattatataa attccataga aaataataga
     3001 acaaaaatag aaaacacact acaatctact ctaaactcag gatttaaaca gatgtatata
     3061 acagtattct gtgtaaatct actagcattt ataatattat tgttctataa agaaaataaa
     3121 actagataaa agagtgttat agtat
//
LOCUS       DAMJWC010000154         3051 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMJWC010000154 DAMJWC010000000
VERSION     DAMJWC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3051
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.159"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            71..144
                     /locus_tag="PC503_003640"
     tRNA            71..144
                     /locus_tag="PC503_003640"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:103..105,aa:Gly,seq:tcc)
     gene            153..269
                     /gene="rrf"
                     /locus_tag="PC503_003641"
     rRNA            153..269
                     /gene="rrf"
                     /locus_tag="PC503_003641"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            543..2561
                     /locus_tag="PC503_003642"
     CDS             543..2561
                     /locus_tag="PC503_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2529588.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1217 a          364 c          513 g          957 t
ORIGIN      
        1 taggatatat atgtagtttt tagagtgcta actctaaaaa attagtttta ctaatttata
       61 aaaatttaat gcgggtgtag ctcaatggta gagttctggc cttccaagcc agctgtgagg
      121 gttcgatccc cttcacccgc tccaaaagat tatgtggtta caatagcaga gaggatacac
      181 ctgttcccat tccgaacaca gaagttaagc tctctagcgc tgatggtact tggtgggaaa
      241 ctgcctggga gagtaggacg tagccacgta atcttttttt gttgtattaa atttaataaa
      301 cctacaattg ttatatgttt ttatttgtct tttatagatt tttttggcaa taaatgatat
      361 agtgaagata attaaatata ttcaatatat ttaatttttt tattttttgt ttttataatt
      421 tttttagaag tttatttttt atgtacttat ttataatttt gggtaaaaac actttgatat
      481 aatttcaaaa attaaaaggt taaaaaacaa agtagaaatt tatgttaaat aaggagatta
      541 atatgagaag aaatacaaaa ttattaacaa cagggattct ttcaatggca atcgtcgcac
      601 ctacaatggc atttgctact gaatctaatg ctatggaaaa taacgctgat ttaaatataa
      661 acttagagaa aaaaagtatc gttttaggta gtacctcaaa agtcagtgtt aagtttaaag
      721 aaaaaccaga tgcagatagc attacattaa agtataaatg ctatgatatg ccattggata
      781 caactttaaa ctataatcaa tcaactgagt catatgaagg aactatcaat tataataaag
      841 acccagaata tctaaatgtt tgggaactac aagggataac aataaacagc aaaaataatc
      901 ctaaaacttt aaacaaacaa gaactagaaa agatgggatt aaatttaaaa gactataatg
      961 taacgcagga atgtataatt gaagatataa cttctagaaa agatgtaaat aaatatttaa
     1021 gaaaaacttc tgcacctatt acagaactta caggaagtga tagatacgaa acagcagtta
     1081 aaataagtaa agaaggctgg aaaaatggtt cagataaggt agttataata aatggggatg
     1141 taagtataga tggcattata tcaactccac tagcaactac atataatgcg ccaatacttt
     1201 tggttgaaaa aaacaatgta cctaatagtg taaaatcaga attaaagcgt ttaaatccta
     1261 gagatgtaat tataattgga gatgagaatg ctatttctaa aactactgct aatcaaatta
     1321 aatcgactgt aaatgctagt caaacacgtc taaagggctc taatagatat gagacatctt
     1381 tattgatagc aaaggaaata gataaaaatc atgatgtgga aaaagtatac ataacaaatg
     1441 ctaatggcgg agaagtggat gcacttacta tagcagcaaa agcaggtcaa gacaagcaac
     1501 caattatatt aactgataaa aatagtatta cagacaacac atataaatgg ttaaagagtg
     1561 aggatttaca aaatgcttat tttataggtg gccctcaaat gatatcaaca aatgttataa
     1621 ataaggtaaa tgatataact aaagataatg ttactaataa tagagtatat ggagcagata
     1681 gacacgaaac aaatgcaaac gtaataaaaa aattctatac agatgatgag ttagaggctg
     1741 ttttagtagc taaatcagat gtacttgttg atgctttagc agcaggtcca ttggctgcga
     1801 acttaaaatc tccaatactt ataacaccaa agacatatgt atctgcatac cataaagaaa
     1861 acttagaagc taaatcggca aataaggtat ataaaatagg tggaggattg acttctaagg
     1921 taatgagctc tatagcatca tcattatcta aacacaatac aactccaaca gaaccaggaa
     1981 atagtggggg caagacagtt atgattgacc caggacatgg tggttcggac actggaacaa
     2041 caggtaaacc attagggggt attagagaaa aagactatac attaaatact tcacttgcga
     2101 caactgaata tttacgttca aagggattca atgtaataat gacaagagac acagataaga
     2161 ctttatctct tggaaataga actgctttat ctaactcttt gagaccagat ttatttacga
     2221 gtatacacta taatgcatct gatacaactg ggaatggtgt agaagtattt tataagctta
     2281 aagataaaga tggagggact actaaaactg tagctacaaa tatattaaat agaatcttag
     2341 agaaatttaa tctaaaaaat agaggtgcaa aaacaagaac actatcaact gaccctacaa
     2401 aagattattt atatgtttta agaaataatg atatgccagc tgtacttgta gaatgtgcat
     2461 ttttggataa tgagaaagat atgagtttac ttaatacatc aaataaagta aaagaaatgg
     2521 gtacacaaat aggtaaaggc atagaagatt cattaaaata gtctacaatg agagcataga
     2581 aaaatttaaa ataaattaat ctgcaatttt aaatttaaac taaagctata agataagaat
     2641 gtaattataa tagtaataaa gactgtatat acattgtgca tataagtgcg aaatgaggta
     2701 tatacagtct ttttatgatt aattgtaaaa ggatttatat tatatgaaga atttacatat
     2761 cttaaggcta cagttaattg tcaagagttg gagtattcat ttgtaataca caataaaagc
     2821 ttaattacta tattttattg tgtgtttgtg tgttttttgt ggatttttat gtcaataaat
     2881 gatatagtat agataattaa atgtattaaa tatatttaat ttttttattt tttgagtttt
     2941 ataagtttat ttttatatat tacttatata ttatttatat tttgggttag atacactttg
     3001 acatattttc aaaagttaaa agattaaaaa taaagtagaa atttatgtta a
//
LOCUS       DAMJWC010000155         3006 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMJWC010000155 DAMJWC010000000
VERSION     DAMJWC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.160"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(50..997)
                     /locus_tag="PC503_003643"
     CDS             complement(50..997)
                     /locus_tag="PC503_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529589.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            complement(1025..1516)
                     /locus_tag="PC503_003644"
     CDS             complement(1025..1516)
                     /locus_tag="PC503_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529590.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            complement(1959..2852)
                     /locus_tag="PC503_003645"
     CDS             complement(1959..2852)
                     /locus_tag="PC503_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2529591.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT         1003 a          426 c          266 g         1311 t
ORIGIN      
        1 ctttaaccaa atgctatttt aataagttta agttttagct ttaaaatact taataataca
       61 ataaaagtga tgtatttaca aataattctt ctggatttaa ttcatttatt gatgtatgtt
      121 caatttttat atttatattt ttcatatctt cataaataat tccaactgga gaacaaatga
      181 aacaagaaaa tccaaaagtt tttgttattt tttttacctt attatcacca aaacttattt
      241 gctttttaca atcgtttata ttttcattgt tattttgtat atcattttta taatacttat
      301 cttttttaat gtcattagac ttatttactg ttttaaaatt actcctattt ttacaactat
      361 agtctatttc aacttctata tacccaaaaa ctatcaagtt acataatttc aaattactac
      421 ctttgtttat aagatttttc ataggtttaa catcaaatat tttactattt acatttactt
      481 ttaatatatc tcttagattt ttaggagctt ttaaagtatt acttatattc aattgtttga
      541 atacaatttt atttacatta gtataaactc tattactttc tattgatatt cttgttggga
      601 atttatctag attacactta taataatagt atatattagc actattcttt ataatcctat
      661 gtgcagaatt tggtaaaact acactcttaa aagatattat ttttttacaa cttgcatcta
      721 ttctccctat gtaaaaacct tgctgtgggt ctaatccacg ttttataatg ccattaactt
      781 ttaccgtatt atttataaac tctatatatt tagaaatata atctttgaaa aatatatttc
      841 cagttttgta cctacttgta tttgtaacaa taatagtgta ggtcaaaatc tcaaatacag
      901 atgcacattt tttatcaaca tatttttcta cttttataat acttccattt gcatcatttg
      961 aaaatacatc attaaaagta gttttcgtta ttctcattgc atccaccttt ctataattta
     1021 aagattactc tatcttggaa ctattttcat aacttataat tgcagtaaca ctaataaata
     1081 aattatcatc taaaatagat gaagtaatat cttgtataag atactttaaa ttaattttat
     1141 ctttattttc tatctttcta ggcatttgta taaatgtact aaagggtatt tttaatttaa
     1201 atgtattttt tttactagaa tttctatttc ttttattgcc tgcataatct aatattgcat
     1261 caatatctat atcaccaact aaaatcaact tctttcctgt aagttgttca tcttctaatg
     1321 atatacattc tatagtatca acaagactta tattgttaat attcatattg taaacatatg
     1381 tctctaatga atttattaca gtttttttag aagctaattt aaaattttta tatgtattaa
     1441 attgagataa ataaagagtc ttttctagtt tttcacatct ttcaaggttg tatattacct
     1501 tattattttc atacataatc gcatcaatct ccctgtatct atatattaat actattcata
     1561 aaaattattt caaattacca ttttttatta ttcactatct agttgttatt tacttttaag
     1621 aaagaatcct tttttacttc attgatttca atttacaagt aaaagtcttt ctgaaaaaaa
     1681 aatatatata tctctattca cttttttata agtaattata atttttatag actaacggtc
     1741 agccttaagg gaaaaggtgt tctttaagtg cagaatttag ataaagtaaa taatcctttt
     1801 ataaataatt ccaagtttta acttaaataa tttgatttac agtataaagt aaattttgaa
     1861 agataatgat atcgatttaa taattacaag taaaagcatg tcaaaataag gctatgattt
     1921 taaaaatcat agccttatca ataaaaattt aatcaaagtt acatttcact ttgaatttca
     1981 ctgtctatta attgaagatt atactgttga attaattcta ttagacgagc tgcatatata
     2041 ctattgccat tttcatcctt cgcagtacta taacctgcct tttctaatgc tttagcttga
     2101 tatatatacg tttttgcatc aaatacacca ttgtttttat accttttatt tgtggctaaa
     2161 aattttgcat ggtcttttat agattcattt ttatcatcat atattctaaa tttatcatct
     2221 ataattgtat ctaaatgttc tttcgtttct aaagtcactg acttgccttt ccaataagcg
     2281 tcagccttta taccaaatag attgttatat tgttttgcca aagttgactt gccccagcta
     2341 gattctatta tagcttgtgc aatagttata gatggaagta ttttataatc cttataattt
     2401 tgtattgctt ctgttttaat ttcatcaata aacttcatat attttgtatc agacttcaat
     2461 ctttctggtt ttataccata atccttaaga ttgtctatat aattatcaac caatcttttt
     2521 tgtctattac taaattctaa ctcatccaaa atatcactta acttatttat tttattattt
     2581 ttagaaaaat tcttaacaaa taaatctgat acttcttgta tctgtgaatc cttaacgttt
     2641 tttaagttat ttttatttaa cacagcaaca atggaagcta catacttcca gttaacttgt
     2701 gcattatttt tacttgctaa atcagcatat tttatatact tactgacatt tatatcatcc
     2761 ttttttatct ctctagatga atattccttc actaatacac ctattaaaat tgatattatc
     2821 agtattataa caatgaattt tttattcttc ataaatattg tcctccctta tactatctgc
     2881 tgaatataat ataccttact tttgtgacat attctttacg aaattttgaa aattttatga
     2941 agatttatga aatatattta attaaaagca ctactattgt tataatatat agttttctat
     3001 cacaca
//
LOCUS       DAMJWC010000156         2793 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMJWC010000156 DAMJWC010000000
VERSION     DAMJWC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.161"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..597
                     /locus_tag="PC503_003646"
     CDS             <1..597
                     /locus_tag="PC503_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2529592.1"
                     /translation="GLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQS
                     LSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQ
                     YGDRLIMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            694..1731
                     /locus_tag="PC503_003647"
     CDS             694..1731
                     /locus_tag="PC503_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2529593.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            2540..>2793
                     /locus_tag="PC503_003648"
     CDS             2540..>2793
                     /locus_tag="PC503_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529594.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT         1064 a          361 c          426 g          942 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaaatt actttagata gtactactat aacaaattta
       61 gctgagtata aaagaactca aatagtaagt agagtttttc aagacccaag ccttggaact
      121 tgtccttcta tgacggttag agaaaattta tctctagcac ttaataaagg gaaattattg
      181 aacttaaaaa aatgtcttcg tcataaaacg aatgacttgg aacacttact tgaaggaatt
      241 tctttggatt taaaaaaata tttagatatt aaagtacaat atctttcagg gggtcaaaga
      301 caatcactat cactaattat gtctagctta gcaagtccta aggtcttatt actagacgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa tagagttaac agataaaatc
      421 gtaagagaga aaaatataac tacacttatg gttactcaca acttgaaaca cgctcttcaa
      481 tatggagata ggttgataat gcttcataag ggtgaagttg tattagatgt aaaagataaa
      541 gaaaaaaaag atttaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtataagaa
      601 attaaaatct tagttttaat cagaaatatt tataatctat catatgaata tatgaacaaa
      661 tataattatt aaattttaag ggaggaaaat aaaatgataa aaagtaaaaa aatattaagt
      721 ttaattatag caggagtact tggtgtatca atgcttactg gatgttctca aaatgatggc
      781 tccaatgctt caaatgaaaa taaagaaaca gatagcaaaa aacaaaaaaa tataggtatt
      841 actcaattag tggaacatcc atctctggat aaagcaaaga aaggattcat caaagcactt
      901 gaagataaag gctataaaga tggagataat ataaaaatag atttccaaaa tgcacaaaat
      961 gatatgccta ctacacaaag tattgctagt aagtttgtat ccgacaaaaa agatttgata
     1021 tatgctatat ctactccatc tgcacaagca gcttataatg ctactaaaga tattccaata
     1081 ataatgactg ctgttacaga ccctgtagaa gctggacttg ttaaatctct tgaaaaacca
     1141 ggtggaaatg tttctggtac atctgattat ctttcaattg ataaaacatt agaattggtt
     1201 aaaacattga ctccaaaagc aaagaaaata ggggttatat acaatactag tgaagttaat
     1261 tcaaaaatcc aagttgattc tctacatgat tatgctaaga aaaataatta tgaagtagtt
     1321 gaaaaaggaa tcagctcttc aagtgaagtt aaccaagcta tttctagttt agttggtaaa
     1381 atagatgttt tatatgtccc tactgacaat ttaatagttt cttctatgcc aatagtttct
     1441 aaagttgcta atgaaaacaa gattcctata atagcctctg aagaaggttc tgtatcttct
     1501 ggtgctttag cttgttgtgg aatagattat gaaaaactag gttataaggc tggagaactt
     1561 gctattgaag tattagaagg aaaatctgtt ggcgatatac cagttactac attagatgaa
     1621 actgaaataa taattaacga agatacacta aaagcacttg acatgcaaaa gttatcagca
     1681 gataatataa agtatataaa gtcagatgaa aatgcaaaat ctacaaaata aaacttatta
     1741 atttcaaaaa ataggtaata tgaagtaggt aatatgaaaa ctttatataa taagtactct
     1801 tatccaccct aaccctttga aaattgtgct tattgtagca atttgaatat tgcatataaa
     1861 gttattcatt ttccataaaa gtcgtctata ttgacgactg attatgaaag ttatataact
     1921 ttctaatcac tacttgagct gtccaaaaga attttaatat tctccagaca gctttttttt
     1981 atgatatttg attgatatac atgtctagtt attccatatt tagtaaatat tttgataaaa
     2041 tttccacatt cacttataac ttaggataac gtttttttca aacaatacat taatttaaaa
     2101 gtattctgag tatacattat ttagtatttt aattaaattt agcagttgac ttttattatt
     2161 gtataattta taatttataa caagtcgaga atacatataa ttttctgact aattaaaata
     2221 ttaaaaggga gagataatta tgaatacttt attaaacaat agaaaatatt attattatta
     2281 tagccactat ttttagggtt tgtacctacg ttttaacata gatacagacc ccttaagact
     2341 actaaaattt tgggattgta tctatgttgg ctatattgtt tataaagttt tcatctaact
     2401 atataagagc cacatagatt aaactatgtg gcttattcgt gtttttacca catagttttg
     2461 tacactatgt ggttttttta tacacaaaat tagcaaataa ttaaaattat aaaaatattt
     2521 tcaaaggagt gttttattta tgtcaggtat tatatctgta atgacgcaaa gtttaatttt
     2581 atcgattatg gcactggggg tttatataac ttacaaaatc ttagattttc cagatatgtc
     2641 tgctgatggt agctacacaa tgggtgcttc tattgtagca ttttctctta ctaatggtat
     2701 ttctcctgta gtagcaactt taatggctat cttatgtggt tgtactgctg gtcttgttac
     2761 agggattctt cacattaagt ttaagatatc taa
//
LOCUS       DAMJWC010000157         2760 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMJWC010000157 DAMJWC010000000
VERSION     DAMJWC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2760
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.162"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            1136..2407
                     /locus_tag="PC503_003649"
     CDS             1136..2407
                     /locus_tag="PC503_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2529595.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
BASE COUNT         1080 a          345 c          349 g          986 t
ORIGIN      
        1 ttttaatcat taaaactaaa gtcaatgtta tctggtaatt atttactaca aatgataaaa
       61 aataattata ttttaaagga taaaatgctg tataaattat tggggtattt tacctatact
      121 tgttacaaat ttacatacca cttagttaat ataaaacaaa tttcaaagag attggacaac
      181 gaataaaaat tgcaatttat ataccatata gttaatataa agcatatttg tgtcgatata
      241 tagttctaac taagtataag atttacatac ctcatagtta atataaaaca catattttac
      301 atgtttgaag attttatcag aaaccctatt tacataccgc atagttaata taaaactatt
      361 aatagtgcta tgttgtttat ttgcattaac aagatttaca taccacatag ttaatataaa
      421 acatgtttag caggagttat gatgataaaa cacattattt atttacatac cacttagtta
      481 atataaaacc ccaaaataaa ctaagtattt tcagtactta cacacataca actctctcaa
      541 atttgcagtg aaccatgagt agtgcaattg ataacattta tcatacaccc tcaatccctt
      601 acattgcaac tgttaaaccc tactttatca aaaatatcgc tcactgcaaa atttatatat
      661 ttttattata tcataaaatt caaactataa aattaaaatg gaataattta tcaatttaag
      721 aacacctaca tatttgtaaa tacttactat attatctatt ctaatagttc ttcttctagc
      781 tagaactaat ataaaaatca tctctgaaag attaggacat actaatataa aaataactat
      841 gaatagatat tttcttgttt taaacgatat ggataaaaaa acttctgaaa atataatcaa
      901 agttctcttt aaataacatt ccattttatg taagtaggca ttatattttt cttaaatgtc
      961 acttaaatgt cagttatata taataatagt aaacaactgt atttcactaa tatttgctat
     1021 tatctaatag tatttatagt ttagatttga tataatacat gtggtaaaat tttgatttgt
     1081 aaaacaaaat tttacctaca tatattaaaa caaatttaaa actaaggaga cctatatgtt
     1141 aaaagtacta aaaggaaata taatttttac aaaaacttca gaaactttca cagtatttga
     1201 aaatagttat attatgctgg aaaaaggtaa agtaaaggga atatttaaag agatacctaa
     1261 ggaatacaaa aacctaaaag tagtagatta cactgataag cttataatac ctggtatgaa
     1321 tgacctccat gcccatgcct ctcaatttaa aaatcttgga atggctatgg ataaagagct
     1381 tttgccatgg cttgaaactt atacatttcc agaagaatca aattataaag atatagaata
     1441 tgcaacaaaa atgtataaaa aatttgtaaa agaactttgg aaatctggaa ctacaagaat
     1501 agcagtgttt gcaacagtac ataaagaagc ctctatgaaa cttatggata tattcaaaga
     1561 agttggtctt ggagcatacg ttggtaaagt aaatatgaat atgaattgcc ctgatacttt
     1621 attagaaaac actcaggatt ctattactga tacagaagaa attataaata agtatagtga
     1681 tacagattct attgtaaaac caataataac acctagattt ataccaagct gtacaagtga
     1741 acttttaaaa ggtttaggag atttatgttt aaaatataat attcctattc aatcacactt
     1801 atctgaaaat tatgatgaga ttgaatgggt tagaagtcta gaacctgaat ctaaattcta
     1861 tggagatgca tataatagat ataatttatt tggtcaaact cctactttaa tggctcattg
     1921 tgttcattgt tctcaggatg aaatagattt aatgagagaa aataatgtta tggcagttca
     1981 ctgtccagct tctaacttta atgttggtag tggtgctatg cctatcagaa aattaatcga
     2041 taataatatt agattagcac ttggatcaga tataagtggt ggacatacat tgtcaatatt
     2101 taaagcaatg gtatctgcaa tacaattatc taaattatat tgggttaact ctggtaagaa
     2161 gtataatttc ttatctttat ctgaggcttt ttatattgca accaaaagtg gtggaagttt
     2221 ctttggaaaa gttggtagct ttgaagaagg ttatgatttt gatgcattga ttattgatga
     2281 ttcaaattta aatcatgaca attattctat acttgaaaga cttgaaagat ttatatatgt
     2341 tggtgatgat agaaatatca ttcatagata tgtatgtgga aaactaattg aagaacctaa
     2401 tatataatta taataaaaat tttaattata tattatggtt aatttataca actataatta
     2461 ataaaagagt atattttaaa tctaaaagct ataggttgaa acatactctt tttattttgt
     2521 ttatttatag ctttagttat taatcatata taaatctaca aaacgtattc ctagtaactt
     2581 acattttttg atatctacaa tcataagact atattattat tggattcaga cctcaaaaat
     2641 attgccttct gaacattatt atattcaaag ctatgttaat ttacaatgat atatctaaca
     2701 tgtactgtaa ttatcaaaca cttctaatct cctatatttt catattaatg taatatcttt
//
LOCUS       DAMJWC010000158         2757 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMJWC010000158 DAMJWC010000000
VERSION     DAMJWC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.163"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..1088
                     /locus_tag="PC503_003650"
     CDS             165..1088
                     /locus_tag="PC503_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF2529596.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1063..1890
                     /gene="panB"
                     /locus_tag="PC503_003651"
     CDS             1063..1890
                     /gene="panB"
                     /locus_tag="PC503_003651"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF2529597.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIIKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1909..2757
                     /locus_tag="PC503_003652"
     CDS             1909..2757
                     /locus_tag="PC503_003652"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF2529598.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSIFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1096 a          333 c          457 g          871 t
ORIGIN      
        1 ttttatgaaa atggtaagat atttatggat ggtatcttgt tataagaact atactttaaa
       61 tgtttttaat tattttgtct tatgtaactc atatcctcag gaatgagatt agaaattaag
      121 atgttgtatc acaaagtgga ggtgatacta ttaaaatagg ctttattggt tctggaaaag
      181 ttggaacatc tttggcaaat tattttttat caaaaggtta ttgtgtttca ggcttttatg
      241 gaaggaatca attatcttta ttagaatcaa caaatttaac aaaaacaaag atttacagca
      301 atttgaaaga tataatttat gaaaacgata tattatttat tacaacatca gatgattcta
      361 ttgaaattat agacaaaaaa ctttccaaat ttaatttaaa acataaatac atttgccaca
      421 caagtggctc tttaaaatct agtatattgt tctgttcaaa aaaagcaggt gcattaattt
      481 attctatcca tcctatattt gcattttcca ataaaaatac tgacataaaa aaaatgaaag
      541 acatttgttt ttccatagaa ggtgataatg aacaagatga tttagttatt caaaatttca
      601 tagatgattt gggaaaccaa ttttttataa gagataagga tacttcatcc acttatcatt
      661 tagctaatgt tttagtttca aatttagtat tatctttact agatatagga gtaagttact
      721 ttattaaatt aggtttatct gaagaggaat ctttaaaagc tatcagtcct ttagtaaaaa
      781 aaaacataga aaatatactt gataatggct ttactaaagc tcttactggt cctgtttctc
      841 gtggagatat aacaccaata aggaaacatc tatctgtatt ggataaaaaa gatgaggata
      901 tttacaaaat actatcctta aacctactaa aaataattgc cttaggaaat gacaattcat
      961 taaaaggtat aaaaaatatt actatagaaa atgcaatcga aaatttaata agtaaatctg
     1021 aaaaatacaa agaaatttac aaacttttag gaggaaaaaa cgatgaaaaa taccatacag
     1081 acttttaaga atgctaaata tgaaggaaaa aaactatcta tgcttactgc ttatgactac
     1141 tcaattgcaa aaataatgga tgagtgtgat ataaatggta ttttaatagg agattcatta
     1201 ggaatggtca taaaaggtga agaaaacact ctatctgtta ccatagacga aattatatat
     1261 catacaaaag ctgtaaaaaa tggcgtaaaa aatgccttaa tcgtaagtga tatgcctttt
     1321 ctatcttacc atgtttctat agaagatgca gttaaaaacg ctggtagact tataaaagaa
     1381 ggaggagctc atgctgtaaa gttagaaggt ggctcaaacg ttataaagca aatagaaagc
     1441 attgtaaatg ctcaaatacc tgtaatgggg catttaggat taactcctca atcagtaaat
     1501 tcatttggtg ggtttaaggt tcaaggaaat accagtgaaa cagcaagaca acttattgaa
     1561 gatgctaaat taatagaaaa agcaggtgca ttctctattg tccttgaagg agtgcctacg
     1621 aaaatagctg agatggtaac taattctatt tcaattccta caataggtat aggggcagga
     1681 attaactgtg atggacaaat tttagtttat caagatatgt tgggaatgtt tggagatttt
     1741 gttcctaagt ttgtaaagca gtatgcaaat ataggagata taataaaaga ttcaattaaa
     1801 aattacatcc tagaagttaa tacaggtgca tttccacaag aaaaacacag cttttcaata
     1861 aatgaatctg agttagaaaa attatactaa tattaaggat ggtacaaaat gcttgtaaaa
     1921 gaaattaaat tactaagaaa tataatcaaa gattggagaa aacatggcta ttctataggc
     1981 cttgttacaa caatgggatt tttacatgaa ggacaccaaa gtcttataaa aaaagctgta
     2041 aaagaaaatg ataaagtagt agtgagtata tttgtaaatc caactcaatt tggaccaaat
     2101 gaagatttta atagctatcc aagagatata gataaagatt ttaaatattg tatggatagt
     2161 ggagcaacag tagtctttaa cccatcacca gaagaaatgt atttaaaagg taattgtact
     2221 accattaacg tttctggact tacagatttt ctttgtggag ctaaaagacc tgttcatttt
     2281 ggaggtgtct gcctagttgt ttcaaagttt ctaaatatag taacacctga taaagcttat
     2341 tttggagaga aggatgccca acaattagct gtaattaaaa gaatggtcaa ggatttaaac
     2401 atagatacag aaataatagg ctgtcctata attcgtgaaa atgatggatt agcaaaaagt
     2461 tcgagaaata catatctctc tgaggaagaa cgaaaatctg ctctaatatt aaataagagc
     2521 ttaagtttag caaaagaaga attagtaaaa ggcaatctaa atccagagaa tataaaagaa
     2581 ttaataacag ctaaaataaa ttctgaacac ttagcaaaaa tagactatgt tgaaattgta
     2641 gatagtgaga cattacaacc tgttaagcaa atagaacatt ctatacttgt ggcaattgct
     2701 gtgtttatag gaaaaaccag actaattgat aattttacat ttgagttaaa tatatag
//
LOCUS       DAMJWC010000159         2508 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMJWC010000159 DAMJWC010000000
VERSION     DAMJWC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.164"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            94..828
                     /locus_tag="PC503_003653"
     CDS             94..828
                     /locus_tag="PC503_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2529599.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDGYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(971..1462)
                     /locus_tag="PC503_003654"
     CDS             complement(971..1462)
                     /locus_tag="PC503_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2529600.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1811..2194
                     /locus_tag="PC503_003655"
     CDS             1811..2194
                     /locus_tag="PC503_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529601.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYNG"
BASE COUNT          977 a          279 c          365 g          887 t
ORIGIN      
        1 acttttatta ttttatataa aagtgataaa aacttatatt ttgtatttaa tagagtgttg
       61 ctaagtgaat atatttaaaa tggaggaaac tttatgaaac aaaataaata tgatgatgat
      121 agatttttta ataaatacag taaaatggaa cgttctacaa atggattagc aggtgctgga
      181 gagtggcatg ttttaaaaaa aatgttacct gatttcaaag gaaaaagagt tttagattta
      241 ggatgtggat ttggatggca ttgtcaatat gcagttgaga atggagcaat ttctgctgtt
      301 ggagttgata tttcagaaaa aatgttaaaa gaagctagaa acaaaacgca acttgataat
      361 ataaattaca tatgtatgcc tattgaagat attaattttc caaaagatag ttttgatgta
      421 gttattagtt ccttggcatt tcattatatt caatcatttg aagatatatg taagaatata
      481 agtaattgtc tttcaaataa aggtaatttt gtattttctg ttgaacatcc tatatttact
      541 gcatatggaa gtcaagagtg gtactgtgat aaagatggca ctaatctaca ctggccagta
      601 gatggatatt ttgaagaagg agtacgtaag tcaaattttc taggagaaga ggttataaaa
      661 tatcataaaa cattaacaac ttatttaaat acgttaatga aaacaggatt tgaaatatta
      721 gaaattattg aacctcaacc agaagaaaaa ctgttagata caattcctga tatgaaagat
      781 gagctacgta gacctatgat gttacttgta tctgcaaaaa aaagataagt aaatataaat
      841 aatcattatt gtagaaaaaa agttgtagaa aataattaca ctaatggaga tgattatacc
      901 agtggtatta attacaccag tagtaaggag gcaaaagcat tcgttgcttt tgccattttt
      961 taagttgcaa ttatacttct acgtagtata tttcgtttcc attttcttct ataagctttt
     1021 tcatatcttc aaattttaaa aatacagtag cagtattatc atttggatgt atacctattt
     1081 tatccatttt taataaatct ttatcaaata caacttttac aacagcctct ttatcattta
     1141 atataccaaa aggagtcaca gctcctttag taagtttcaa gtatttttga agtctttctt
     1201 ccgatgcaaa actaagaggt ttactatcaa tttgttgacg aatatctttt aaatctgctt
     1261 ttttgtcttt acctaataca actaaaaaat gttcttttcc tttagcatca cgaagaaata
     1321 ggttttttac aacaaattcc atatgtaatg tttttaattc ttccatttct tcaattgtat
     1381 aaactggtgg atgatttaca gcctcataag gtatgcttaa ctcatctaat tttttatata
     1441 cttcctgttg ttgattgttc atgatttcct cccattagaa atttatttta tatataaata
     1501 atattatcac agaaaacttt aaaagaaaac gttttatata atatagacaa tagattatat
     1561 ttttataaag aagcaagaat actcaataaa acttaaagaa attaaacaat ttctaaaaat
     1621 accttgaaaa tagaacctta tttgccattt ataaattata taaaaaggga ttatataaag
     1681 tcatatatga aaaaactata ttatactatc ttttcttttt ggaataaact atactttaaa
     1741 tatagatatt taatttaaat aaattttaca gtattaatag taaattatct tagaaaggaa
     1801 tgtgctttat atgtctacag acaaagttgt tggaatcata gatgaagaaa cggcagaact
     1861 tgcaggaatt gaatatactg gtaaaattta tgcttcttct ggtgttataa aacatataaa
     1921 gaaaaaacat agatgtcaac tgagtaagga tatttttaat gatataatag acactataaa
     1981 aatggtatta aagtcacctg aatatatagg aagtcatcct aaaaaacctg gaaaaagtgt
     2041 ggagtttata aaaaaaattg atgattatat tttagtagct acagaattag atacaaaaaa
     2101 aggatattta tatgtatctt caatgtatgc tataaaagaa gcaaaattag aaagtagagt
     2161 aaacagtgga agagtaaaac aatataatgg ttaacataat attattaatt ttccctaaaa
     2221 tattgaaaaa tattattata taagttataa tattaatata cacgtagata tttattagtt
     2281 agatttgagg ttggaaaagg cacccaatac gctactatag agtagttaat agagatgcag
     2341 gatacgccgc cctgccaaat ctaattaaat taaaaagaga ggattaattc ctctcttatt
     2401 gtttttttga gatactaatt taatctataa tagaaagatt gaaggtcgtt tatacaaaaa
     2461 aattttcagt tatatacatt aaactaatta aataagatat ttataatc
//
LOCUS       DAMJWC010000160         2442 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMJWC010000160 DAMJWC010000000
VERSION     DAMJWC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.165"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            95..568
                     /locus_tag="PC503_003656"
     CDS             95..568
                     /locus_tag="PC503_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2529602.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(937..1494)
                     /locus_tag="PC503_003657"
     CDS             complement(937..1494)
                     /locus_tag="PC503_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529603.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            1752..>2442
                     /locus_tag="PC503_003658"
     CDS             1752..>2442
                     /locus_tag="PC503_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2529604.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTL"
BASE COUNT          901 a          321 c          303 g          917 t
ORIGIN      
        1 ataatattct aaatttataa aacaaattgt attgaattga atttatttaa gatatataat
       61 tataattaaa ataataataa aggtgttgtt tataatgttc aaagaatact taataagaga
      121 attaaaagaa gatgatatta aaaatgcatt agacttaatc tggaacgtat ttgaagaatt
      181 tgaatctcca gattattgtg atgaaggaat tacgacattt catcaattta tagaatataa
      241 ctctattatt gaaaaaatca aagaaaaaac tctcttcttt tggggttgtt ttgactctaa
      301 aaaacttatt ggagtcttag ctattagaaa tttaaatcat atatgtatgt tatttgtaga
      361 taaaaactat cataaacatg gtgttgcaaa aaaattaatg actacaggca tacaatactg
      421 tatttgtaat aaatttaatt taactgaaat aactgtaaat tcatcacctt atgctgttga
      481 agtttatcat aaattaggat ttaaagatac tgctgttgag caaattgttg acggtatacg
      541 ttttacacct atgaaattgt taatataata aattaaataa aaagcaaagt ctcttaaata
      601 ttttatagtt actttgcttt taaaccaaga tttaaaataa tactatcttt tttgtttttt
      661 aataatatac tttaaaatcc ttactaatat gaactataat ttattttttg atatcctttt
      721 tgattaacat ataaattaat tcaattatta aacataaact atgttgtttc tctttatatc
      781 tcttctttgt aaacaatatt gggcatttga aaataaatat tcttaaaata tactgttctc
      841 ctgttgattt tcctttggta caaatgataa aaatttaatt tacatgcccc ataatgaagt
      901 gttcaataaa taagttaaaa taatttattt acctccttaa tcatattttt tatgaatacc
      961 taataacaca gtatcaatag aatcggctaa accttttata gcttcttctt tactcaaaag
     1021 tgatttccca agttgcaaag tcgaataacc atgaagtaca ctcattatta agtttaatac
     1081 ttcacctgta ttctttgtat ttagattaca agaaagaata agtttttcta ataaggattt
     1141 atattcatca aagatttcta atgtttcatt atttccatgc caagtagccc actgaattgt
     1201 ttcataaaca ccaggattag aaattataaa attaaagtat gctatactta tacactttat
     1261 agctgtatct ccaaaatttc caatagtcgc ctttatcatt tgactattca tctctctcat
     1321 tcctttatga gctacttcaa gtaataaatc atctagactt tctatatgat tgtacaaaga
     1381 tggtgtacgt attcctagct tttctgcaat aacttttaaa gaaactttgt taagcccatc
     1441 tttattaact atatctgatg tagcttgtat aactatttct ctactaacac gcatgatttt
     1501 ccctctttca tttaaaatta attactttat tagtttagct aatctaatta gtttcgtcaa
     1561 ttattgtaat ttataaaatt ctttatacta ttataaaatc ttgacagttt aattataatt
     1621 taatataata ctaattgaat tagttttaat actaatataa ttagtattat attaaattct
     1681 atattacaac attattttat agtttgatta atttaacaat cactaatata tcaaactgaa
     1741 aggagatttt tatggaaaaa aaatatttcg aaattcatgg agttccttca atcctttggg
     1801 gaaatccttc aagtaaatta tatatttaca tacatggaca atgtggcaat aaagaggagg
     1861 ctgaagcttt tgctaatatt gcagttccac atgagtgtca agttttaagt gttgatttgc
     1921 ctgaacatgg agaacgtaaa agagaaaaaa attcatttaa cccatggcat gttgttccag
     1981 aattagtatc tattatggaa tatgcaaagt gccactggaa tcaaatttcg ttatatgcaa
     2041 atagcattgg agcatggttt agtatgttaa gctttgaaaa agagaactta agagagtgta
     2101 tttttgtatc tccaattcta gatatgcaac agctcatttc aaatatgatg ctttgggcaa
     2161 atgtatcaga agaacagctt aaacatgaac taattatccc aacttcattt gggcatactc
     2221 tttcatggga atatctacaa tatgtaaaac aacatcctat cactcaatgg aatgtaccaa
     2281 caaaaatatt atatggtaaa catgatgaac ttactgaaat cggtgttgta gagaaatttg
     2341 tagaaaagtt taattgcaac cttactatta tagaaaatgg caaacattgg tttaacacac
     2401 cacaagaatt aaattcatta tatgaatggt taaatacttt ag
//
LOCUS       DAMJWC010000161         2208 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMJWC010000161 DAMJWC010000000
VERSION     DAMJWC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.166"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(121..1413)
                     /gene="brnQ"
                     /locus_tag="PC503_003659"
     CDS             complement(121..1413)
                     /gene="brnQ"
                     /locus_tag="PC503_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2529605.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          735 a          372 c          246 g          855 t
ORIGIN      
        1 tatcaaacag gattaataat gttcttttat ctacaataat ttaataattc ttttaaatat
       61 aaaaaggaat tgcctatata atttaaaggc aattccataa ttatcaatta gtttttatta
      121 ttatgcagtt ttactgcttt tagatggaat aaagtttcct attattcctg ctattacaac
      181 tggaactatc cagttaaatc ctaatgaagc aaatggtaag ctattaacta gaggaatttt
      241 tacaccaaaa cttgttgcaa ctgttaatac acttactaat aatgccatgt atgcagcaca
      301 tttgaacacg ttgtcatttt taattttatt actaaataat gctagtataa ctagagttat
      361 agttgctgga tataccatac ttagtatagg agaagagaat tgtattattg tacttactcc
      421 aaagtttgat atgattgcac taaatacaca aactactata actatatgct catactttaa
      481 ttttccatct gtaagtgttg agaaatattg accagctgct gaagaaagac ctatagctgt
      541 tgttaaacat gctaatgcaa ctataatagc caataaaatt ttacctgtag ttccaagtaa
      601 agctgctgtt attgcaacta ttaaagctgt ttgttgaaca tcttgtccat attgttgaga
      661 cacagttgct ccaagataac ataatccacc ataaactaat gccattccta ttactgcaat
      721 tacacctgca cttattgtgg ctttcatctt ttctttctca cctgtataac ctttagctat
      781 tactgacatg attataattg atgcaaatac actagctgcc aatgcatcca ttgtttgata
      841 accttgagtt ataccttctg caaatacatt ttgtattaaa gaactgtctc ttatttctcc
      901 taatggagat acgatacctt taactattaa tactgctaaa gctataagta aagctggagt
      961 taatattgac ccaactatat ctacaacttt tgatggtctt attgttaaaa ccaatactag
     1021 agcaaagaat actatagaga atattactgg gcttattcca gaacctattg taggtaatat
     1081 acccatttca taagttgttg ctgctgttct aggtattgct aaaagtggcc ctatacagat
     1141 taccattgca catcctaatg caatacttaa tcctttgcct gcccttgaga acatcttcga
     1201 tgtgtctcca ttgaacttag ttgctgctat aactgctaat aatgccaaac caccatctgc
     1261 aaaaaggaat cctatgaaag ctactagcca actacttcca gataaaactc ctagatatgg
     1321 agggaagatt aagttccctg caccaaaaaa cattgcaaat agtgcaaatc caattacaat
     1381 tacatcttta aaattgattt gtttctcacc catttaaagc acccccattt gaattttact
     1441 accttttact aaaaaataag tccaatctct taattaaatg aaaacctttt gacgagattt
     1501 tatttaatta tacatttttg acttaaattt gtcaattatg tttcataatt tataaaatct
     1561 tcacaatatt taatacaact ttcttaatta aacaaaatca acctgtatac tttaaacata
     1621 gttggttttt tgttttttct ctaatttttc ttgataaaat taactattcc gaataattaa
     1681 aatattaaga ctttttagat tattcgattt attattaagt tgtattgctt tatatactgt
     1741 atatatcact ctcctttttt acattcatat aatcttttta attcaattta aattttaaat
     1801 attttgtgtt tattatataa tctgaaaaaa aagcagtcaa tagcattttt aattttttta
     1861 attttcaaaa ttatgattct taaaaaatcg ttttcctttt atcataacac ctatttacgt
     1921 taattcttgt agtattttgt atttattttg ctaaattgac agttaacttt attcaatttt
     1981 tattctactt gcgtagattt gcctcttgtt ttttactctt aaaaccattt tttctgaaaa
     2041 ttccttatta tgatttatca acttattttt cttcataaca attactctct aacttccaac
     2101 ttacttaaac tttgcagttg ctagtattca cgtttacata cttatatgtc ataattaact
     2161 aaaaattctt aatatatctc tcaatgaaaa caatttactc atttattt
//
LOCUS       DAMJWC010000162         2095 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMJWC010000162 DAMJWC010000000
VERSION     DAMJWC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2095
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.167"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            95..493
                     /locus_tag="PC503_003660"
     CDS             95..493
                     /locus_tag="PC503_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529606.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    929..1192
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1343..1894
                     /locus_tag="PC503_003661"
     CDS             1343..1894
                     /locus_tag="PC503_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF2529607.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          883 a          197 c          303 g          712 t
ORIGIN      
        1 taataagata tataagaaac ttgaaaaaat ttgtaatttt tagttatata tatattataa
       61 tgaactagtt aaaaattttt atgaggggga aaatatgaat aagaagaaaa aattgattgg
      121 gatagctata tcttttctac ttataatcag cattataaat ccattacaag tagaagcaga
      181 agctattatt gagtctagtg tatacatttc ttcaataaaa gagaattata catatgataa
      241 tactaaattt aaaactatta aatctaaaag tagacataaa agtaggaaat ataataaaag
      301 taaagtaaag ttgaaaaaac gaagtataag aactaaaaag tatggatatc aaactataaa
      361 taaatataaa agacaaaacg caagaagaca taatatccta acaaaattaa tattgtccat
      421 aatagtcata tttttggtta tagttttagt agtgctaata tttattaaaa gaaagaagaa
      481 aaaattttac taaaaataat taaaagaata tcattttttt aatcattggt atctatttaa
      541 taatatgatg taattaaaat ggagtaatat tctgtttcaa aggaggcata taaatacagg
      601 aatgagtatt aaatgatggt taattaagta aatttattga taaatgtact taattaactt
      661 tgaagaattt aattcctcat gaatcaaaat ataaaattac atcaacagtt attcacaaaa
      721 ttaatataag aagaattaga gccaaagagc agactattag accattaaag taattattca
      781 tagaattttg tatatgaaaa gaaatgtata gtataattta ctttttttat aaaaaataga
      841 ttacaaaata tattttttat aaaaaggtat tgacattttt tagaaaaaag aatatcatta
      901 ttttaacaac aaaattcaat acaataaatt aaatcctatg acaaggaaga gtagttaaat
      961 ttaggttcag tatagagagc tgaggatggt ggaatcttag caagaaaaaa tttgatgaat
     1021 ggcccttaga ggaataaatt gaaatcatag ttttgagagt agactttatc gtcagtcgca
     1081 cgttatagcg aataaggtat gtaagtacct gataatgaga tgtatgaaaa ttgaatttta
     1141 tattaatttt tatataattt aggtggcaac gcggataatc tccgtcctat tagtttagga
     1201 cggagttttt tattttactg aaaatttaaa agatagaagg tggtgagaaa gatgttatga
     1261 atttcaaaag ctaaagatga tgatatagta ggttggcaaa aaaataaatt gaaaattaaa
     1321 aaaataggag gaagtacaaa aaatgaaaac aaatacaaaa aaattaactt taaatgcaat
     1381 acttttagcg atgggattat taatacatca aatcacacca gctataggat taccaatgaa
     1441 gccagatgta ccactagcaa tgttatttgt aatattggtt ttaaatagag atgattataa
     1501 aacttgtttg atagcgggta tagtaacagg aatatttaca gcacttacat caagttttcc
     1561 gggaggtcaa attcctaatg taatagataa aactcttaca gcaaatatag tatttttatt
     1621 aatgaatatt agttataata tgccttttat aaaaaaatta gctaagaaaa cacaagatac
     1681 tgtagtagtt gcaataataa tgccaatagg aactcttgta agtggaacta tctttttatt
     1741 agcagctcaa gctatagttg gtcttccagg ggcttcattt acagctttat tcttagcagt
     1801 agtattacca gctgttttaa taaatctagt tgcaggaata tttttattca agattgttag
     1861 tctatcaata agaagagtta gttatcaagc ttaaacacga aataatattt tactttataa
     1921 agcattataa taactaaata acataagaat aaagtagatt ataactattt tattcttatg
     1981 ttgtttaaag atttggtatt atatatttat ttttaataaa atatttatat agtaccaatt
     2041 acacttaatt taacagataa attatcatac ctatataata ttcttatatg tatct
//
LOCUS       DAMJWC010000163         1947 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMJWC010000163 DAMJWC010000000
VERSION     DAMJWC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1947
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.168"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(14..1231)
                     /locus_tag="PC503_003662"
     CDS             complement(14..1231)
                     /locus_tag="PC503_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF2529608.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(1422..1835)
                     /locus_tag="PC503_003663"
     CDS             complement(1422..1835)
                     /locus_tag="PC503_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2529609.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT          663 a          324 c          224 g          736 t
ORIGIN      
        1 tcttatataa gaattatttt aaatcaagat tatctagtat ttttaaaaat atttttacag
       61 cagtatccaa gtcatctaca gagacacttt cattaggatt atgacttacg cccccagcgc
      121 atcttataaa taccatacca atatcagtta tattatccat ttcctgagca tcatggccag
      181 caccactata aatataaaaa ggattaagat ttaaatctat aaaacttttt tctatgattt
      241 ttgttatttt attagaacat ggtacaggaa cattttcaaa agcaagttca cttgtataat
      301 taagttttct attttcacat atatgtgata tttcattaaa tatcttttct acagaattat
      361 caagaatttc ttgtgaacaa gagcgtacat cgagtgtaaa ttcagctctt tcaggtacca
      421 catttgatga agatggatag aaattcatct ttcctacagt agcaaccaaa tcagtagtcg
      481 ttttagctac tttttcgata gctaatacac attcacaggc acaacatcca gcatcaagtc
      541 tcatattcat tggaagtgta ccagcatgtc cagacttacc atttactgat atcttaaaac
      601 ttttaaatcc tgtaatactt gatacaattc cagcaggaag agattcattt tctaaaacag
      661 gaccctgctc aatatgaaat tctaaatatg catctacatc ttttctagga tgcaaatttg
      721 ttaagttttt tgtattaaat ccaaactttg ttacagcttc ttcaagtgta attccatttt
      781 catcaacaga tttaagaagt tcctctttaa aagtaccagc aaaaacttta cttcccatta
      841 aagaagtttc aaatctagtt ccttcctctt cagcgaaagc aattagctta atattgaaag
      901 gataagacct attattgtgt tttgcttctt caagaccaac tagaggcact attataccta
      961 acataccatc aaatatacct ccacacttta cactatcttg atgagatgca actactaatg
     1021 tgggagcatt tggaaagctt gatttatatg tacctataac gtttccaatg tcatcaattt
     1081 caatatcaag atttaaacct tccatccatg aactaattaa atcaatagat tttttatgtt
     1141 cttgagtcaa gataagtctt gtaagaccat ttgttgttga acttattttt cctaatgttt
     1201 gtagataatc catacatttt tttcctaaca tatttacctc ctaaaaatat aatttttatt
     1261 taagctaaga ttagctttta tacttataat ttttgaactt tcaaataatt ttgtatgtat
     1321 agtaaaatac tattttagta ttaataatga tataaaaaca taaagtctgt agacgaagag
     1381 cagaagtttt aatttaaaaa tatgaaatat gatttttatt attatagtat ttttctataa
     1441 taatatctct ttccagttag aggataattt tcaagtgaaa atactttatg gtatccaaat
     1501 ttctcataaa atttaggtgc ttgaaaactg aatgtatcta aaaaaacata tttacaacct
     1561 cgttctttag caattttttc agccttatat aaaagttgac ttccagtacc tttatatcta
     1621 agcttctcac taacccataa gtattttata gaaagccaat taccatgagt aacacctata
     1681 aaacctgcaa caattttacc tgctttatct cgaatatata ttcctaaatc cactgggttt
     1741 ttatcttcaa gtctagcaag attatatttt aataatcctt gaaaaatagt atcttcatct
     1801 tgtttttcta ttttttctgt aatttctaat tccatatttg aactttctcc ttgtataatc
     1861 ttttgtatat tggtattttt taataaaatc agtagaaaga atatagttta acattattct
     1921 aataggcatt tatgctaatg tcaaact
//
LOCUS       DAMJWC010000164         1925 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMJWC010000164 DAMJWC010000000
VERSION     DAMJWC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.169"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            119..235
                     /gene="rrf"
                     /locus_tag="PC503_003664"
     rRNA            119..235
                     /gene="rrf"
                     /locus_tag="PC503_003664"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            242..316
                     /locus_tag="PC503_003665"
     tRNA            242..316
                     /locus_tag="PC503_003665"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:274..276,aa:Asn,seq:gtt)
     gene            321..395
                     /locus_tag="PC503_003666"
     tRNA            321..395
                     /locus_tag="PC503_003666"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:354..356,aa:Glu,seq:ttc)
     gene            401..476
                     /locus_tag="PC503_003667"
     tRNA            401..476
                     /locus_tag="PC503_003667"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:434..436,aa:Val,seq:tac)
     gene            482..558
                     /locus_tag="PC503_003668"
     tRNA            482..558
                     /locus_tag="PC503_003668"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:516..518,aa:Asp,seq:gtc)
     gene            569..643
                     /locus_tag="PC503_003669"
     tRNA            569..643
                     /locus_tag="PC503_003669"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:601..603,aa:Thr,seq:tgt)
     gene            658..742
                     /locus_tag="PC503_003670"
     tRNA            658..742
                     /locus_tag="PC503_003670"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Tyr,seq:gta)
     gene            752..825
                     /locus_tag="PC503_003671"
     tRNA            752..825
                     /locus_tag="PC503_003671"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:784..786,aa:Gly,seq:tcc)
     gene            836..912
                     /locus_tag="PC503_003672"
     tRNA            836..912
                     /locus_tag="PC503_003672"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Arg,seq:tct)
     gene            922..997
                     /locus_tag="PC503_003673"
     tRNA            922..997
                     /locus_tag="PC503_003673"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:955..957,aa:Gln,seq:ttg)
     gene            1009..1084
                     /locus_tag="PC503_003674"
     tRNA            1009..1084
                     /locus_tag="PC503_003674"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1042..1044,aa:Lys,seq:ttt)
     gene            1087..1175
                     /locus_tag="PC503_003675"
     tRNA            1087..1175
                     /locus_tag="PC503_003675"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1121..1123,aa:Ser,seq:tga)
     gene            1193..1283
                     /locus_tag="PC503_003676"
     tRNA            1193..1283
                     /locus_tag="PC503_003676"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1227..1229,aa:Ser,seq:gct)
     gene            1292..1368
                     /locus_tag="PC503_003677"
     tRNA            1292..1368
                     /locus_tag="PC503_003677"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1326..1328,aa:Pro,seq:tgg)
     gene            1454..1529
                     /locus_tag="PC503_003678"
     tRNA            1454..1529
                     /locus_tag="PC503_003678"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1487..1489,aa:Trp,seq:cca)
     gene            1590..1666
                     /locus_tag="PC503_003679"
     tRNA            1590..1666
                     /locus_tag="PC503_003679"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1624..1626,aa:Pro,seq:tgg)
     gene            1673..1749
                     /locus_tag="PC503_003680"
     tRNA            1673..1749
                     /locus_tag="PC503_003680"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1707..1709,aa:Ile,seq:gat)
     gene            1753..1828
                     /locus_tag="PC503_003681"
     tRNA            1753..1828
                     /locus_tag="PC503_003681"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1786..1788,aa:Phe,seq:gaa)
     gene            1836..1912
                     /locus_tag="PC503_003682"
     tRNA            1836..1912
                     /locus_tag="PC503_003682"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1870..1872,aa:Met,seq:cat)
BASE COUNT          484 a          442 c          524 g          475 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaaa taaaaaaagt
       61 attgacaaaa atagtaaaaa atgttaatat tatacttgtc ctagcaacaa gaaaaaaatg
      121 tggttataat agcggagaag atacacctgt ttccattccg aacacagaag ttaagttctc
      181 tagcgctgat ggtacttggt gggaaactgc ctgggagagt aggacatagc cacgtgaatg
      241 ttccaaggta gctcaacggt ggagcaaccg gctgttaacc ggtaggctgt gggttcgagc
      301 cccacccttg gagccattat ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg
      361 cggtaacagg ggttcaattc ccctacgagt caccatttgt gggatcatag ctcagctggg
      421 agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttggtc ccaccatttg
      481 cggcctggta gttcagttgg ttagaatgcc agcctgtcac gctggaggtc gagggttcga
      541 gccccttcca ggtcgccaaa ataaaaatgc tggtgtggct caacggtaga gcagctgact
      601 tgtaatcagc aggttgtagg ttcgattcct atcaccagct ccatgtaaaa ctaatacgga
      661 ggatttcccg agcggccaaa gggggcagac tgtaaatctg ttgtcatcga cttcggtggt
      721 tcgaatccac catcctccac caattaaata tgcgggtgta gctcaatggt agagttctgg
      781 ccttccaagc cagctgtgag ggttcgatcc ccttcacccg ctccaaagaa agcgtgggtg
      841 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      901 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      961 catgtatgcg taggttcgag tcctgcatcc ccagccaaat aaaaatatgg tctattagct
     1021 cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc
     1081 accaatggag aggtgtccga gtggtttaag gagctggtct tgaaaaccag tgacttcgaa
     1141 aggggccgtg ggttcgaatc ccaccctctc cgccaaaaaa atgactgaat ttggagaagt
     1201 actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg
     1261 ttcgaatccc tccttctccg ccattcaaaa acgaggtgta gcgcagtttg gtagcgcaca
     1321 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaac ttaagctttt
     1381 agttcagttg gttagagtgc ccaactcatg gctagtaatt ctagggtttg agtccatgaa
     1441 ggttattctt cataggggtg tagctcagtt ggtagagcgt cggtctccaa aaccgtgcgc
     1501 cgggggttcg agtccctcca cccctgccaa ataaaaagga cttgaaaaaa gttggatttt
     1561 agagtagtat aagatagtaa ataagatttc gaggtgtagc gcagtttggt agcgcacatg
     1621 gtttgggacc atggggccgg gggttcgagt cccttcacct cgaccaagaa aagggcctat
     1681 agctcaggtg gttagagcgc acgcctgata agcgtgaggt cgctggttcg agtccagcta
     1741 ggcccaccat ttgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc
     1801 ggtggttcga ttccgcctct gggcaccagg aatacggcgg tatagcttag ttggctagag
     1861 cgttcggttc atacccgaaa ggtcataggt tcgactccta ttaccgctac catctaacta
     1921 tatca
//
LOCUS       DAMJWC010000165         1835 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMJWC010000165 DAMJWC010000000
VERSION     DAMJWC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1835
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.170"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            80..364
                     /locus_tag="PC503_003683"
     CDS             80..364
                     /locus_tag="PC503_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529610.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(1135..1350)
                     /locus_tag="PC503_003684"
     CDS             complement(1135..1350)
                     /locus_tag="PC503_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529611.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1361..1828)
                     /locus_tag="PC503_003685"
     CDS             complement(1361..1828)
                     /locus_tag="PC503_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2529612.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT          746 a          198 c          231 g          660 t
ORIGIN      
        1 agaatatgga aaaacttgat tagtacatta ttaattaggg tataaaatgg tgtaaataga
       61 atgataaggg gtggatgaaa tgcttgtata taataaaagt ttttatccta atgacatatt
      121 tccaagatta gatttttcaa aaataaaaaa acagttaaaa ttgatagata atgacctgtc
      181 agattttgga agcatatgta taatagaaaa agaacattat acaataagtg taaacagtat
      241 aggtgaaata aatgtgtatt atgatttaga gtacgaaaat aaggtgtata gaatagttta
      301 tgagattgaa aagttattta aatctcaagt tggaaggttt agcatatcta catacagaaa
      361 ttgataatta aaaaagtaga aattaaaaaa cttaatacta aagatataga taaatatatg
      421 aggtaacagc tagagagagt tgttaccctt tttaaatact aagtatatat tattcttatt
      481 aattttttgt aaattcacta aaagaccttt ttatagaata ttattttctt tttttattaa
      541 ataggtaaat cagtaaaaat gcaattccag ttccaattat tattccaatg atattttcta
      601 taattaattt ttttaatata aaagtaaata ataaaaatgc tatacataaa cctaaaatat
      661 atcctttaaa ataggttgaa agttttcttt tcatataatc accaacttgt atcagattta
      721 gtttacttaa ttagagtata acagtgttgt aacttcaaag agtatctaaa agattacaaa
      781 tgttagataa aatcatcaat aatgtaattt ataacacgta gctataaact atgcaataat
      841 ataaatggag gtataagtaa atgaaaaagt tccatgtttt gctaacagtt taaataaata
      901 ttaggtagaa aagaatgtat ataggaatct gtggtaaaat tatcaattta aaagtattat
      961 ttagtgtgat acagttctta taggtaatgg ataacaaata gataaaggaa cagtttcttt
     1021 cttagaacat attttgttat gactttaaac aaagttaata ttaatgtcaa taatatagta
     1081 aaagaataaa aatcatatag tataataaaa aagagtgttt ctaaacactc ttttttaatc
     1141 attttcatct tctacatatt caagtatatc acctggctga cagtctaaag ctttgcaaat
     1201 ttcgtttaga gtggtaaatc taatagcttt tgcttttcca gtttttaaaa ttgataaatt
     1261 tgcatttgta atatctattt tttctgccaa atctttaagt gatattttcc tttttgccat
     1321 cattacatct aggttaacta ctattgccat aacatcacct ctatatcgtt aaatcattat
     1381 cttcttttat ttttatagct ttatcaaatg tttctgcaat tacaaagcac attagtgcaa
     1441 atataaaaga gataatcata agtggtgaga taccgccact atcagttcca aaaattctta
     1501 tattattagt atttaaatta taaccattga tacattcaat tatagtgttt atcaataaac
     1561 aaaatcccat taccttaaac ctttttacat tttcaagtac gaatggggaa tacttagtac
     1621 tattaattat aaatatcaag aataagatga ctataaagta gtcagaaaaa tatagtattc
     1681 ttgcaattaa agcgattact ttgtcagaac taaaatcata taaaaacata ggtatcatac
     1741 ataagaatat tataccagca actcctaaaa gtgataatag aaaatataga aatactgata
     1801 atatattact aaaaaatttt gtaatcataa aatat
//
LOCUS       DAMJWC010000166         1810 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMJWC010000166 DAMJWC010000000
VERSION     DAMJWC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1810
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.171"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            81..650
                     /gene="mocA"
                     /locus_tag="PC503_003686"
     CDS             81..650
                     /gene="mocA"
                     /locus_tag="PC503_003686"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF2529613.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            647..1666
                     /locus_tag="PC503_003687"
     CDS             647..1666
                     /locus_tag="PC503_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF2529614.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
BASE COUNT          727 a          165 c          346 g          572 t
ORIGIN      
        1 atatatatag ataatatcaa tagagatatt ataaaaatca tagaactatc aatatattat
       61 aaataccaag gatgatatat atgataaatg cagtgataat ggcatcaggc tttgccagaa
      121 gaatgggagc aaataaactt ttattaaatt ataaaggctg ttctataata gaacatgtat
      181 ttagagaagt tagcaagatt gattttcatc aagttgtagt agtaagtcaa tatgaagagg
      241 ttttgttatt gtgtaataaa tatggttttg aatatataga taataaaaat gcaaatatag
      301 gtcaaagtga atctataaaa ttaggagttt taaatagctc aaaatgtgat ggttatatgt
      361 tctttgtagg agaccagcca tttattgata acttatatat agataaaatt ataaatactt
      421 ttaaattaga tagagatttt atagtaattc caagatacaa agatatgtgt ggaaatccag
      481 tcatattccc atatagcaag aaagaagaat tgttggcact taaagaagat gaaaaaggta
      541 aaaccatttt aaaaaattca tcaaaaataa agtatgtaga agttcctaaa gaaatgttat
      601 ttgatatcga tacaaaaatg gactatgaga gaattggggg taaattatga agctaataaa
      661 aactatagat gctgttggac aagttttatg tcacgacata actcaaataa tacctggaga
      721 atttaaagga agaaaattta aaaagggtca catagtaaaa gaagaagata ttccagtgtt
      781 attatctctt ggtaaagata atttgtatgt atgggaaaag tcagaaggaa tggttcatga
      841 aaatgaaggc gcattgtttt taaaagaact aactgctgga gaaaatttag attttagtga
      901 aataaaagaa gggaaaatag attttatagc agcatgtgat ggtctattaa agatagatgt
      961 tgatgcactt tttgatttga attgtgttgg agaaataatg atggctactc ttcataataa
     1021 ttttatagta aataaaggtt taaaagtagc tggaacaaga gtgatacctt tagttataga
     1081 tgagaaaaaa ttagaagatg caaaaaaagt agttggtaat agaaaaatag taaatgtagt
     1141 accttttaaa cctaagaaag taggaattgt tactacagga aatgaagtgt tttatagcag
     1201 aattgttgat aaatttggac cagtaataga agaaaaagta aaaggctttg gttgtgaagt
     1261 tataggacag actatatgcc cagatgataa agaaattata aagagtgcaa taaaagaatt
     1321 tataagtcaa ggagcagaac ttatctgttg tactggtggg atgagtgtag acccagatga
     1381 tgttacgcca acagctataa aagaaactgg agctgattta gtgacatatg gttcaccaat
     1441 attaccagga gctatgtttt tacttgctta ttacggagaa gttccaatta tgggtatacc
     1501 aggatgcgca atgtatcaca aaactacagt atttgatata gttttatcta gggttttaat
     1561 tgatgaaaag cttgataagt atgatatagc tagatatggt catggtggcc tttgtatgaa
     1621 ctgtgatgta tgtacttatc ctgcatgtaa ttttgctaaa atataaagtt attaaaaaag
     1681 agtatttaca aattaagtac tctttttaaa tatgaaacaa aacagctaga atgatgtttt
     1741 aaaaaaagca tatttattta gaaattataa taacttattt tcaatgtgta aaagaatgaa
     1801 taaagttgca
//
LOCUS       DAMJWC010000167         1801 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMJWC010000167 DAMJWC010000000
VERSION     DAMJWC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.172"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            175..1503
                     /locus_tag="PC503_003688"
     CDS             175..1503
                     /locus_tag="PC503_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2529615.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
BASE COUNT          613 a          207 c          326 g          655 t
ORIGIN      
        1 tggtttttat aattttttta tatttaaaca taactaaaaa taaaagatta ctaaagctaa
       61 gtagagttta ttttatttta ataaataata aagctatttt tctatatatt ggcataatat
      121 atgcttattt aactatgaaa ttaaaattaa ataggattaa tgaggaggaa aaaaatggga
      181 agtaatgaac tgaaaaagac tcttggcgta tcagcagcat tatcaactgt tgttggttcc
      241 gttataggag cgggcgtatt ttttaaacca caagcagtct atacattaac tggaggagct
      301 ccaggtcttg gtatattggc atggttaata gctggaatca taactataac agctggtctt
      361 acagctgcag aggtatcagt tgcgatacca aaaactggtg gaatgatggt atatataaaa
      421 gaaatttatg gagaaaaatt aggtttttta actggatgga tgcaaattgt attattttat
      481 ccagggatga tggcagcatt aggtgttata tttggagaac aagcatcggc actaattggt
      541 agtccatcac ttttacttcc aatagcaatt ggaattataa taatagttgc agggcttaat
      601 atgttaggtt caaaaactgg aggagtcata caaactgttt ctacaatttg taagttaata
      661 ccacttattt taataatggt tgttggattt attaaaggtg gtggaaataa tccaatactt
      721 acacctatgg ttggtgaagg attaagcctg ggtagtgtac taggtcaagt tttaattgct
      781 atattatttg cttttgatgg atggatgaat gttggtactt tagctggaga aatgaagaat
      841 cctggaaaag accttccaaa agctataata ggtggattgt cagttgttat ggctgtttat
      901 tttataataa atttagcgta tctttgggta ttaccagcta atgaattagc aaattatgct
      961 tctcctgcat cagcagttgc tgaagttata tttggttcaa tgggtggaaa aataatatct
     1021 gtaggtatat taatttcagt gtttggagca ttaaatggat ttttactaac tggttcaagg
     1081 gtggcatata ctttagctac agataagact ttaccaaagt atggtatatt ttctaaatta
     1141 aattctgctc aagttccagc aaatgcaata gcattagtat ctgttattgc atctatatat
     1201 gctttgtcag gtcaatttaa tttattaact gacttagctg tatttgctac ttggatattc
     1261 tatgtattaa cttttatagg ggttatgaaa cttagaaaga ctcatccaaa tataccaaga
     1321 gagtataaag ttccattata tcctattgtt cctataatag ctatagcaag tggtatattt
     1381 gttgtagtta atcaattgtg ttttgcaggt atgaaaacta ctatgatatc tataggaggt
     1441 cttgtaataa cagctatagg cttaccagtg tatgcttata tgactagagg agtaaaaaga
     1501 taaaccaagt agtttacaaa tgcttcataa ttaaaataaa agagactgtc tcaaatagag
     1561 ataagtctct tttttattgt taaaatggta aagatatgtt taattttaca aaaaaagagc
     1621 gttccatgaa ctaaaaagtt tattttaagg tattcatttt atttttagtt ttttgattat
     1681 aaaattaaac atctaaaaaa ttatttattt taaaatactt tattttaaag tgttttttat
     1741 caaactaagt ggtatctgta caacaaatat tatacatagc ttttatgaaa attaaatctt
     1801 t
//
LOCUS       DAMJWC010000168         1761 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMJWC010000168 DAMJWC010000000
VERSION     DAMJWC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.173"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            113..1603
                     /locus_tag="PC503_003689"
     CDS             113..1603
                     /locus_tag="PC503_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2529616.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
BASE COUNT          682 a          185 c          351 g          543 t
ORIGIN      
        1 tatattcgat aaaataaaat ttaaacatat aatattttat gtatatatta ataaaaggac
       61 atattgtgtt ataatggtat cgtataaaat catttacggg ggtggtatta aaatgtttca
      121 atttgaaaca caaatacaca aattaagaca tgatgtttta actgcaatag ctagacttgg
      181 aaaagaagat aaccttacca gagaagcaat ggataatatt cagtatgaaa taataaaagg
      241 tgagaaacct acatacagat gttgtgttta taaagaaaga gctataatat ctgagagagt
      301 aaatgtaagt atggggttac aaccaggtca agataagata gatttagata caatggatat
      361 agaagaagat gaacaaatta tatatatttt ggaagctgca tgtgacagtt gtccaataaa
      421 tgaatttaca gtaacagata tttgtagagg atgtctagca catagatgta aagaagcttg
      481 taaatttgga gctataacac atgtcggagg aatggcctat ataaatcatg aattatgtaa
      541 ggcttgtgga atgtgtaaaa aagcttgtca atatgatgcc atctcagagg ttgttagacc
      601 atgtaagagt gtttgtccaa ctaatgcctt aggatttgat agagaaaata tgaaagctat
      661 gatacatgag gataaatgtt taaactgtgg agcatgtatg tcagcatgtc catttggagc
      721 aatatctgat aagagtttga tagctcctgt agctagaaag ttagttcaaa aagagaaaat
      781 gtatgcggtg gtagctccag ctataacagg tcaagttgaa gcaaatgtta catatggtca
      841 aataaaaaat gctataaaat cactaggatt tgttgatgta ttagaagcag cttgtggagc
      901 agatgcagtt acagttcatg aaagcttaga atttgctgaa agaatggaaa agggagaagc
      961 ttttatgaca aattcttgtt gtccaggatt tgttggttat atagaaaaaa catacccaaa
     1021 tcatgtaggg aaaatatctt ctacagtatc tcctatgata gctagtggta gatttataaa
     1081 aagtcatgaa ccagatgcta aagttgtatt cataggacca tgtacagcca aaaagagtga
     1141 ggcagctaag aaagaattaa aaggagctgt tgattatgta cttacttttg aagaaataat
     1201 ggcattattt gaggcatttg atatagactt ggctaagtgt tcaaatgaag atatagatga
     1261 tgcatcaatt tttggaagag gttttggagc tgctggtggt cttacaaaag ctatagaaaa
     1321 ttatcttgct gaaaaaggta ttggtgttaa ttttgaacct gtaaagattt ctggttcaag
     1381 agaaatcaag aaaactatga ctatggctaa tttaggaaag ctagaaggta attttataga
     1441 aggaatgatg tgtgaaggtg gttgtataaa tggttctggt aaattcttat caggtgcaaa
     1501 ggttaaagcc acttttgata gaaaaaattc tcaatcaact aagaaaagtg tcttagcaaa
     1561 tacaaagata aaagatttta gtaatataaa tttagaaaaa taaagataat acaaagcaac
     1621 aaaaatacat attgttaata gagttgttct aagttgaggt ttaacttttg gacaactcta
     1681 tttttattta tatatttaat tattgaacaa ctaaaataaa aattatatac acttaaaata
     1741 aaaattacat atataatatt t
//
LOCUS       DAMJWC010000169         1733 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMJWC010000169 DAMJWC010000000
VERSION     DAMJWC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.174"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(759..1076)
                     /locus_tag="PC503_003690"
     CDS             complement(759..1076)
                     /locus_tag="PC503_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529617.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(1386..1733)
                     /locus_tag="PC503_003691"
                     /pseudo
     CDS             complement(1386..1733)
                     /locus_tag="PC503_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          618 a          225 c          176 g          714 t
ORIGIN      
        1 gcaaattttt agggtataat ttttaaaatt atattctact atcaaaagat atgaataaat
       61 gattgtatat attatatcaa tttttatatt tcatagtcca ttttttcatc acattttcgc
      121 ttgtcaagaa taatatcttt aagagtgaag cgtttgatgt aaatctggac tttgtttttg
      181 agacattttt gaaatattta ttaaatcttt cgattatact tgtaatatat attatagata
      241 ttacttattt tagtaaaact aaaggatgat gctacaacat tccagttatt tcccaaaatt
      301 ttaatttctg aagtatactg tttacattat ttttaatcta ttttatctaa agtcgataag
      361 gcttcttatt cattaactga cctatataca gatttaaaat tacttattaa ttcttttgag
      421 tccttgtatg aaacatattt aaagtatttc ttatctaatg tattaaacat ttttgtatta
      481 cagaatgagg ataacttgta gctattgtct ctttgaaata agtcatctgt gtttactcct
      541 aaaactactt atatctgtag attttataag ttctccatct tatataattt ctttgattaa
      601 ttgttttctt aaattattca taaaaaaatc tccgttacaa tatttgatta tatttaaatc
      661 attgctataa agaagacttt tattaacttt gaaaaacaaa ttattttaat tgctggtgat
      721 tagttgctac cttcttttga tattaattct attagatttt atatagttat atatctcttt
      781 ctaactaagt aatataatat tactgttata gtagctacta atattattgc tattattgta
      841 atatctaatc tttttgtaaa taatcctatt gctatatatt caaaacctgt tacatatcga
      901 taaagtactt ctagtttaat agttcttttt ctatctatat ttccatattt tgattctaat
      961 ttattaaaat atttttcatt acaaaaacca attttaattt caattaaaga tattattgta
     1021 gttaatatta taattcccaa tcccataagt ataagataaa tgttcctaaa attcatagaa
     1081 gatacctcct ttataatata atcatcaact catgttgtat taattttcct aatcaaagta
     1141 taacagtaac acaagtataa agagtatcta aaatattaca aatattaaat gagaaaaaga
     1201 tggtaagtta accccaccat cttatttttt atctactaat gaatgatgct acaaaagtta
     1261 gtataaaaaa tgaaacaaac aatataatga acttgtgtaa tttacttagt tggaatgctt
     1321 tattacaaaa taataaaatt aatgctgaaa caattgcaaa aagtagatat tttataatca
     1381 ttttatcacc tattgatttc tacagattgt aagtagtatt tggttacaca agcacctcct
     1441 ttattataac gtatttttta aatttaaaga tttttccaga tgttatattt gactcaaggt
     1501 acattgtaat taatctaact ataagtggca agtactgtcc tataccagga atagcaccag
     1561 ccaaaagtcc tgaaatccct ataccagcat cagttaaagt taatgcaact cctttagaaa
     1621 gatataaatt aaaacctatt ctagcccaaa ctattttatt tatttcagct tttctataat
     1681 ataattcaag tagtgtcaat atcgttcttc ttaaggtttt taattagctt ata
//
LOCUS       DAMJWC010000170         1627 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMJWC010000170 DAMJWC010000000
VERSION     DAMJWC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.175"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            163..1599
                     /locus_tag="PC503_003692"
     CDS             163..1599
                     /locus_tag="PC503_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF2529618.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          668 a          167 c          274 g          518 t
ORIGIN      
        1 taaatgtaaa tacaattata gctaaatgaa taattgtatt aatatttatt tgtaatatgc
       61 ttaatataat ttgcaatttt acataagttt gttaagtaca taactaattt aagaatatgt
      121 atttatatat taaaaattta ttatgagggg gacaatttta ttatgaaatt ctataaaaga
      181 atattaacat tgactttaag tatttctttt gtatttgcaa atattcaatt agtagatgca
      241 atatcatctg tagaaaaaat acaaggaaaa aataagtatg aaatcgcagg taaaatagca
      301 gataaaaatg catataaaac tgctatatta attaatacta gtaactctat tgcagatgga
      361 ttaagtgcaa gtggactagc aggagcttta aatgccccta tactattaac tgaaaaaaat
      421 actataccaa ctgagacatc tgcaagatta aaaaatgtat caaaagttta tataattgga
      481 ggaacatatt ctattagtac atctgtcgaa aattcattaa aatctaagaa aatgaaagtt
      541 gtaagaatta agggaaatga cagaataaaa acaagttata atgttgcaaa agaaataaat
      601 tcaataaaaa aagtcaatac tgttatgcta accaatgcat ataaaggaga agcagatgct
      661 ataagtattg catctgtagc agcaagagat aaagcaccaa taattcttac taatggacaa
      721 agtatacctt tttcaactag tggtttaaag tcttatgtaa taggaggaac agcttcaatg
      781 agtaccactt tagtaaacaa tactaaatct actagactag gggggagtac tcgttttgaa
      841 actaataaag caataataaa taagttttat aaggatgcta gagagtttta tatagctgga
      901 gcttatgaat taacaaatgc acttgtagga tcttctttat caaaacatgg tccaatggtt
      961 ttagttaatg atggtagcaa taaaagcatt ttaaaaaatg ctaagaagat aacttctata
     1021 ggatatatag attcaaatat agtacaacag tgtttaaata taacaaatgg aattggagat
     1081 attaatactg gggttgtaaa aaatgttaaa cctactacaa agactataaa agatggaatg
     1141 tataaggttg gaaaagatat ctcagcaggt gaatacttaa taacttcaaa ctcaggaagt
     1201 tatgcttctt attatgaagt tacaagtgat agtacaggta atgctgatag tatactttca
     1261 aatgatattt ttagtgggac tagatatatc accttaaaga atggtcaata tattaaaatt
     1321 gaggattcaa caatgacatt agcaaagtat gctaaagccc agaaggccaa gaatggtaag
     1381 tttggaaatg gtatgtataa aattggatta gaaattcctg ctggagaata tattataatg
     1441 tcaaattctt ctgatgcata ttatgaagtt agaaatgata gcttaggtaa tgcagaggga
     1501 atagttacta atgatacttt ttcaggaaga agatatataa cggttgagga aggtcaatat
     1561 ttaatattaa atgattgtta tttaattgaa aatgaataga tgtaattgta tttaatagta
     1621 aatcata
//
LOCUS       DAMJWC010000171         1573 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMJWC010000171 DAMJWC010000000
VERSION     DAMJWC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.176"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            12..410
                     /gene="tnpA"
                     /locus_tag="PC503_003693"
     CDS             12..410
                     /gene="tnpA"
                     /locus_tag="PC503_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF2529619.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            407..1570
                     /locus_tag="PC503_003694"
     CDS             407..1570
                     /locus_tag="PC503_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2529620.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNKGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
BASE COUNT          673 a          166 c          279 g          455 t
ORIGIN      
        1 tgttagtttt tatgtataaa tctaacaaaa atatagttta tgattgcaaa tatcatattg
       61 tattttgccc taagtatcgt aaacctgttt tagttggcga agttgaaaag atgttaaaag
      121 aaatactacc atataaagca gatgaacttg gagcagaaat aatagaaatg gaaactgata
      181 aagaacatgt gcacttatta atatcttgtg accctcaata tggaattcat aaagtagtaa
      241 aaggtttaaa aggctttagt tcgagagtat taagagagaa ctttccacat ttaaagtcta
      301 gtatgcctag catgtggact aatagctatt ttgtaggtac tgttggttct gtgagtttag
      361 aagtagttaa acaatatata gaaaatcaac aagttaggac aaagaaatga taaaaactca
      421 tagagtgaaa ttaaacctaa ctagaacaca atttgaatta gtaagggaaa agcaaatgga
      481 aagtgctaac tgttggaact acatagttaa cttatctaaa gaatactatt ttgaacataa
      541 acaatggatt aaaaagaatg atatacaaaa gttaatcaaa ggtaagtaca atcttcatag
      601 tcaaactatt caagctatat cagataaatt tgatgcaaat agaaagacta tatcagaatt
      661 aagaaaaaaa ggtaatacta aagcaaaata tccatacaag actaagaaat tttatataat
      721 accttttaaa gctagtgcta ttaatagaaa tgctaaaggc aacttaaaat tatcaatgtc
      781 aaaaggcagg tatttagaat tagattttaa tgttgagaat ataaaaactg ctgaaatagt
      841 atggcgaaat ggatattatt tatactacac ttttgacaat gaattaaatg gagttgtagc
      901 caaaggcact aataccgtag gtgtagactt aggggaaata cattcgatag ctagtgtaac
      961 aaataaaggt gtagggctta ttctatctaa tagagaaggc agaagtatta aacaatttag
     1021 aaataagatg tatgcttata tatctaaaag attaagtaaa tgtaaaaaag gtagtagaca
     1081 atcaaagaag ttatggagat taaaaaataa gataagaagt aaaacagata atcagttaat
     1141 gaatttatat catcaaacaa ctagaaagtt tatagacttt tgtgtagagc agaaggtatg
     1201 tgaaatagtt cttggggata taaaaggggt tgaaaaagat actaagaaaa agaaaagatt
     1261 aaacagagtt aatagacaga aaatatctca aatggagtat ggtcgaataa aggactatat
     1321 aaaatataaa gcaaaagagc aaggtattga agttaagtta gttaaagaaa actacacttc
     1381 tcaaacttgc ccaaagtgtt ctaaaaaaca caaaccaact ggtagaactt atagttgtac
     1441 ttgtggttat gaaactcata gagatatagt tggtgcttgg aatattttaa ataaaaagca
     1501 taaatatggt ttagtagatt ttagaataaa tcataagcaa ccaataaatt taaaagtatc
     1561 taccgtttga gcc
//
LOCUS       DAMJWC010000172         1337 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMJWC010000172 DAMJWC010000000
VERSION     DAMJWC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.177"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            27..101
                     /locus_tag="PC503_003695"
     tRNA            27..101
                     /locus_tag="PC503_003695"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC503_003696"
     tRNA            116..200
                     /locus_tag="PC503_003696"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC503_003697"
     tRNA            210..293
                     /locus_tag="PC503_003697"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="PC503_003698"
     tRNA            323..399
                     /locus_tag="PC503_003698"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="PC503_003699"
     tRNA            407..482
                     /locus_tag="PC503_003699"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="PC503_003700"
     tRNA            571..659
                     /locus_tag="PC503_003700"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="PC503_003701"
     tRNA            663..738
                     /locus_tag="PC503_003701"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="PC503_003702"
     tRNA            745..818
                     /locus_tag="PC503_003702"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="PC503_003703"
     tRNA            833..909
                     /locus_tag="PC503_003703"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="PC503_003704"
     tRNA            933..1009
                     /locus_tag="PC503_003704"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="PC503_003705"
     tRNA            1017..1093
                     /locus_tag="PC503_003705"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="PC503_003706"
     tRNA            1102..1177
                     /locus_tag="PC503_003706"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="PC503_003707"
     tRNA            1185..1258
                     /locus_tag="PC503_003707"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="PC503_003708"
     tRNA            1265..1336
                     /locus_tag="PC503_003708"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAMJWC010000173         1263 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMJWC010000173 DAMJWC010000000
VERSION     DAMJWC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1263
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.178"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(111..1151)
                     /locus_tag="PC503_003709"
     CDS             complement(111..1151)
                     /locus_tag="PC503_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2529621.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT          390 a          240 c          130 g          503 t
ORIGIN      
        1 ggataataaa atgctattac acaaaaaaac acttagaaaa tagttttcca agtgtttttt
       61 atcaatttta taatttcaaa ttttagaatt gagaataaaa agcctaatta ttatacatct
      121 atttttctgt acaatgtagc tagtgatatt ccaagttttt tggcagctag ttttttagac
      181 ttagtatcat ttccgtaaaa ctttaacact ttctttatat aggctctttc aaactcttca
      241 agtgtaagta tgtcttgttc catacttatc tcatagtcac tttcctcaag taactttata
      301 tttatattat ttaacttaaa atattcaagt atctttctat ttattattcc tttatgtatt
      361 attccatctt cctcaagaag gtttaatgcc agttctatag tattttccaa ctctctaata
      421 tttcctggcc aaggatactt aagcaacatt tgttccacat ctggctctat atggtacacg
      481 tttttcttca tctttctcga atatttgtct ataaaattgt ttattaatat ttgtatatcg
      541 tctcctcttt ctctaagtgg aggcacttct aaaggtatta cattcaatct atagtataag
      601 tcttctctaa atttattttc cttaaccaac tcaaataaat ctctattagt agctgatatg
      661 attctaacat ctatatcaat tagttcattt gaacctattc tcgtaaactt cttttcctgt
      721 aataccctca ataactttga ttgtagttga attggcatat ctcctatctc atctaaaaat
      781 acaacccctc cattggccaa ttcaaactta ccaattttac cttttgaatc tgctccacta
      841 aaagctcctt ttgtatatcc aaaaagttca ctttctagta aaggttctgg tatagcagca
      901 cagtttatag caacgaatgt tttattccct ctgtttcctg cgagatgaat ggctcttgct
      961 attaattctt ttccagtgcc actttctcca gttatagcta cagtagaatc actatttcca
     1021 attttacaaa ttctattctt aagagcacgc attacatcag actctccaat tatggagtct
     1081 actgttgttg ttccccaaat attatatact tccattccac catacattac tgaatcactg
     1141 tgtttgtcca taaaatatca actccaaata agtattctat ataataatca ttcacattat
     1201 ctatttaatt atatcataac agaaaagctt agttataatt taataatatt attttaaaac
     1261 aaa
//
LOCUS       DAMJWC010000174         1184 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMJWC010000174 DAMJWC010000000
VERSION     DAMJWC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1184
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.179"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            353..1033
                     /locus_tag="PC503_003710"
     CDS             353..1033
                     /locus_tag="PC503_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529622.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT          525 a           70 c          180 g          409 t
ORIGIN      
        1 ataatagaaa ttttaattta tatctatatt aaattgttaa agatataatt atgagaataa
       61 aaaatatagc tttgaattat ataattgtat atgcttatct ttatacagta aataaaaaat
      121 caaatgaaat accaaataaa gtgtatatct taaaataact tactagagat acaaggatgc
      181 tatgtgaatt ttgaagtgtg cagtttagat aataaatata tataaataat aaagaaaatg
      241 gatttatagt atttaaaatt tcttataagg gtaaaaaatg ctattagaaa atgtactaaa
      301 aatatttttc caattcttta tagaaaaata atgatattta ggagagattg taatgcaaat
      361 tgatgtattg ataattgatg gagataagaa tagttctcaa gagctgaaaa attttttaga
      421 aggaaagggg ataaatgtct atttagcata taattgtaaa gatgctatta taaaaatatt
      481 tagcaagaaa tttgacttaa tatttttaga gataatttta gttgatggtg atggttggga
      541 tttttgtaaa aaaattagaa atataactac ttgcccaatt attcatataa cttatataaa
      601 tgaaaatcaa agtattttaa atgctttaaa ttctggagga gatgattatt taataaagcc
      661 tttaaattta gaaatattat atgcgaaagt taaagctatt ttaagaagaa gagatttatt
      721 tttaaataat aataaaaata atataaaact agaagattat aatagagcta gtggagtaat
      781 aaagttagaa aataaaatga taaagttaac tccaacagaa aatagattat taaattactt
      841 tatagagaat gctgaaaaga ctctaactat taaggagata tatgaacatg tatggatgaa
      901 tgagtattta gatgataatt atagtgtagt ggttgctgtg agtggattaa gaaagaaaat
      961 agagaaagat tataaaaatc ctcaaaaaat tataacgata agagaagtag ggtattactt
     1021 taacaagata taaagcttta taaacagaat gaatgataag gcatagataa tatgttagta
     1081 tattataaga gtttttgttc taacgatata tttgtaaaat tagatttaat ttacttaatt
     1141 aaattatagc agtagaataa atataaaaaa tgtctgaaat atta
//
LOCUS       DAMJWC010000175         1136 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMJWC010000175 DAMJWC010000000
VERSION     DAMJWC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.180"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(231..722)
                     /locus_tag="PC503_003711"
     CDS             complement(231..722)
                     /locus_tag="PC503_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF2529623.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT          438 a          162 c          100 g          436 t
ORIGIN      
        1 cttttaagat aaataaaaat atctacaact atatattgca aaaatttaaa actaatttat
       61 atatgctaat ataaatattt ataaagacat aagacaaatt tacctacaga tttaaattta
      121 acttatatat tttaaaaggc taatataata tgtattttct tctatacaat caaaaggctt
      181 catatctaag atatgtgatg acactaatat tcacaatttt ttagtaatta tcacattata
      241 aaaaatatta cagctagtcc atcatcagat gcttcttgta taaacttttt aagctcaatt
      301 agatttgccc atacatattc aaaaaaatca tcttcactct catcattcat aacaggataa
      361 atattatttt ctaacatctc attaatatta aatctttttc taaatgcttg ttcttccaaa
      421 ctgttcattg cttttgatag tttttttaca tcatttgctg taatcaacat gacaggaaat
      481 tctccatcaa tttccataag tatgtttcca cttagtacta atttgctaaa tatattatca
      541 tcatctccac caaaaggaca acctgtcaaa gtaaagtgaa tggcatgcca tgctttatca
      601 atattgatag tactattttc gttggcatct tcaaaaacaa aatcttgtaa gttttcttct
      661 gcttgctgta atttaaaaac attctcttca cttattttag tataacatcc tatcatcccc
      721 ataattacat tcctcctaag tagcgttttt ttaattgtaa cttataatta aacttagtta
      781 caataaaata tattgagaaa agtattattt catcttaaat ttaaatacct atattatcaa
      841 ctaaaattct gtgtttatag cgtaagtatt attatttttt cctaaaaatt aaatgaatca
      901 gaagttctat aggcaatatt gactataaat aagaactatt acttttaaaa aaaaatttaa
      961 gaaattatac tgtagaatca tgctctactt attagcttta aataaaaaat aaatcatgtt
     1021 ctcaaattaa ataataaata acaataaatt taaattttaa actataagag tttctgaagt
     1081 gttaataagc ataccaataa ttatatgtgt aagaatttga tttaatagat atgaat
//
LOCUS       DAMJWC010000176         1085 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMJWC010000176 DAMJWC010000000
VERSION     DAMJWC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.181"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(410..610)
                     /locus_tag="PC503_003712"
     CDS             complement(410..610)
                     /locus_tag="PC503_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2529624.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(835..1011)
                     /locus_tag="PC503_003713"
     CDS             complement(835..1011)
                     /locus_tag="PC503_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529625.1"
                     /translation="MFRDKMDKCTHMLTAYISNSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
BASE COUNT          409 a          141 c          101 g          434 t
ORIGIN      
        1 cttattgtag attttttact ttttaactaa ttttatattt attatatttc agtgaaaaaa
       61 tagaacattg aaacatatag atatgtttta attgcttttt attaacaaat tactaaaaat
      121 gttatatcag aattgaatac aaaagaaaga gtatgtattt atgagatagt tgaaaatttt
      181 gatgtgccac aactaaaatt attatattac tatatattta attaaaagag tacttgtagg
      241 tttaagtaca tactttataa atatattttt gttagattta ttttataaaa agtatttaga
      301 ctaagtatta tttttaagta ttttcttgtt gaagttattt tttccttttt tacaaaattc
      361 gtaaataaaa aaaagactct taaaagagtc tttccgaaaa atctatatat tataatatag
      421 ttatattttc tgcttgagga cctctagcgc ctttaactat atcaaagctt actttttgac
      481 cttcttctaa tgatttaaat cctgaagttt gtatagctga gaaatgagca aatacgtcat
      541 ctccactttc cattgatata aatccaaatc ctttttcatt attaaaccat tttactattc
      601 cattattcat taaaaatact cctattaacc tatatcaaga tatacttgat ttacttgtgt
      661 attaccacaa atattattgt atcatagatt aacataaatg tctatttaat tataattttt
      721 agttaacatt tttatttatt cttaatatga aaataaattt aaacatttta tattaccaat
      781 atattaatgt aaatgtagat aaaactaaaa agggttttct agaaaaaaat ctgtctaatt
      841 atacttactt accaatacca tcacttgatg caagcaagat tccacaactt tttctccgta
      901 ctctaatata aaatcatcta actgtgtatc tataaaatca caataatcgt atgaattact
      961 aatataagca gttaacatat gtgtacattt atccatttta tctctaaaca taatgtattt
     1021 atccccctaa aaaactttca tgaaaaacaa aaagaaaata tctttttggc aactggctga
     1081 cataa
//
LOCUS       DAMJWC010000177         1001 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMJWC010000177 DAMJWC010000000
VERSION     DAMJWC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.182"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(162..845)
                     /locus_tag="PC503_003714"
     CDS             complement(162..845)
                     /locus_tag="PC503_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF2529626.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
BASE COUNT          392 a          155 c           78 g          376 t
ORIGIN      
        1 acattttaat taatttatac actgcttact atacttaaaa tacttctatt aacttataca
       61 ttgcttacta tattttaaat tctttaatta atctatacaa tatttgctat atataaagta
      121 tatcaaataa cagcttcatt tttttgtaaa tttacagaaa gttaattttc attaaatgaa
      181 tcatctttat tgataaacat aattccaaag accactgcca aaataaaaaa acatattagt
      241 attgattttt ccacgaaaat ttttgtaaaa aaagttccta aaatagctcc agatataaag
      301 aatataataa tagcataata ctgtaaactc ttttttatca taaaaatatt cttagtatgt
      361 atataatgaa ataaagtttc tgtagcactt cttaaatttc cagtacacat tgtcgttgca
      421 aaactattcc catttacttt tctaaaactc tctacttgca ttgaacaaat aaaagaaata
      481 gcaacattta caaacatatt aaatcttcct ctaggaataa atgaaacaat aagtattgta
      541 atcatttcaa ttataatgat aacctgacgc caatgaatct ttgtcttatt atttgtaaaa
      601 tactttctta tcttctcggc tataaataca cctaacataa atgccaaaat aggaatcaaa
      661 taataaaatg attcctttac attaccttct gctatattaa gcccaaataa aactatattt
      721 ccagtttgtg cattagcaaa gactttacct cttaccacat aagtataaat atccaaaaat
      781 cctcctgtta ttgccaacaa agaacataaa aagaatgatt cagacatctg actcttgctt
      841 gtcatatata aacctctcgc tttctaatga tagatacaaa atcaaaatca ttttagattc
      901 tatttttcat tgatataaaa aaattattta tatttaaata ttgtctatat ttatacatta
      961 tttgtattta tatagcattc atatttattt atatttaaac a
//
LOCUS       DAMJWC010000178          990 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMJWC010000178 DAMJWC010000000
VERSION     DAMJWC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.183"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            313..780
                     /locus_tag="PC503_003715"
     CDS             313..780
                     /locus_tag="PC503_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDF2529627.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          380 a           65 c          164 g          381 t
ORIGIN      
        1 gtgatattaa tattattagt gtatattaat attcccttga aattaaaaaa acatagatat
       61 ttcagtaatc taaaatagtc tacaaaaata acagttttag caaaattaat aagaatacat
      121 atagatttaa acctaaaagt atgaacatgt ctgtttttta caagattaaa atttatatta
      181 tatgataaaa ttaacttaac tatttcaata agacttataa tttttttctt tatactagac
      241 cttattgaaa cctttatagt ttaattctaa ttatatatta taaataaagt atgtgtatat
      301 taaggaggta atatgaagtt tttaaatgtt ttagtagtag ttgaagatat tgagaaatca
      361 aaaaagtttt attatgatgt tttggggtta aaggtaatct gtgattttgg agaaaatgtt
      421 gtattagaag gtaatatatc attacaagaa aaaaagcttt ggttagaatt tattaataag
      481 agtgacagtg aagttaagtt caatggaaat gatgctgagt tatattttga ggaagataat
      541 tttgatactt ttgttgaaag attgagtaca atgaaagata tagattatgt tcatctagct
      601 atagagcata ggtggggtca aagagcaatt agattttatg atttagatgg gcatattatt
      661 gaggttggag aaactatgtc atctgtgtgt agacgttttt tagatagtgg tctttcaata
      721 gatgaggtag ctaaaagaat ggatgtaact gtcgaatata ttgaatcagt tttagaatag
      781 atggattata ttaaagtaaa attgaggtga aggctgtaag taaacttgtg tgaaaacaaa
      841 tttgcttaca gtttttattt ttctaaaata aagaatataa tacttgttta gctttatttg
      901 agtttttaaa aatattatga tatttcttat atatttatac taaagtttaa atttagaaaa
      961 aatatataaa agatagttat atttactatt
//
LOCUS       DAMJWC010000179          787 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMJWC010000179 DAMJWC010000000
VERSION     DAMJWC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.184"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..>787)
                     /locus_tag="PC503_003716"
     rRNA            complement(<1..>787)
                     /locus_tag="PC503_003716"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          238 c          182 g          195 t
ORIGIN      
        1 cgtccatccc ggtcctctcg tactaaggac aggtcttctc aaatttccta cgcctgcgac
       61 ggatagggac cgaactgtct cacgacgttc tgaacccagc tcgcgtacca ctttaatggg
      121 cgaacagccc aacccttggg acctactaca gccccaggat gtgatgagcc gacatcgagg
      181 tgccaaacct ccccgtcgat gtggactctt gggggagata agcctgttat ccccagggta
      241 gcttttatcc gttgagcgat ggcccttcca cgcagaacca ccggatcact aagtccgatt
      301 ttcatccttg ctcgacctgt atgtcttgca atcaagctct cttttgcctt tacactctac
      361 gtacgatttc cgaccgtact gagagaacct ttgagcgcct ccgttacctt ttgggaggcg
      421 accgccccag tcaaactgcc cacctgacag tgtcccaaga ccagattcat ggcctatggt
      481 tagagtccca gtactacaag ggtggtatcc caaggatggc tccgccaaaa ctggcgtcct
      541 ggtttcaaag cctcccacct atcctgtaca tgtagtacca agacccaatg tcaagctaca
      601 gtaaagctcc atggggtctt tccgtcctgt cgcaggtatc cggcatcttc accggaatta
      661 caatttcacc gagtctgttg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc
      721 ggaacttacc cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt
      781 actgggg
//
LOCUS       DAMJWC010000180          776 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMJWC010000180 DAMJWC010000000
VERSION     DAMJWC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.185"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     regulatory      11..104
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            187..672
                     /locus_tag="PC503_003717"
     CDS             187..672
                     /locus_tag="PC503_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2529628.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          343 a           67 c          126 g          240 t
ORIGIN      
        1 tatgttatta ttcagatata ggcaatatta gataaatcta atgacgcaaa actataggga
       61 ctaaaatctt tatgtaataa aggtcatgtc agccagttgc caaaaagata ataattcttt
      121 ttgttaaaag tatttttaga gttatatatt ttaataactt aatatttggc aagaggaggg
      181 cttaagatga tatctgaatt aatgttaaaa aattttcgca aatctagcat caattttaag
      241 actaaaatta aattgaattt aagagaaaaa ccagacataa atagtttgaa attaaaaagt
      301 ataccagaag gtaaaattgt taagttaaag tgtgtagatg gaatatgggc agaagttgag
      361 agtaattatg acaaaggttg gttactttat aaatatttag aaagattaag taatgctaaa
      421 aacaatagta atgatacaat aaaaaataga aaaaagaatt acataggaaa tataagaaca
      481 aatggattaa gtttagaact tagaaatgat agaacattag aatctaaagt tataactaca
      541 atccctgatg gttttaaagt tgaagtatgt tatagcgttg gaaaatgggc aagagttaat
      601 atcaataaaa atgaaaaacg atattctgga tatgtatata atcaatacat agaagagcat
      661 ttaagtttat aatacgatac tagcaagctt taaatatatt aataaatcgc aaaaaagaat
      721 cccattaatg ggattctttt ttgtagaaac attataacag aactaaagag aataaa
//
LOCUS       DAMJWC010000181          753 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMJWC010000181 DAMJWC010000000
VERSION     DAMJWC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.186"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>753
                     /locus_tag="PC503_003718"
     rRNA            <1..>753
                     /locus_tag="PC503_003718"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          207 a          156 c          227 g          163 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tac
//
LOCUS       DAMJWC010000182          742 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMJWC010000182 DAMJWC010000000
VERSION     DAMJWC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.187"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            176..682
                     /locus_tag="PC503_003719"
     CDS             176..682
                     /locus_tag="PC503_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF2529629.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          297 a           74 c          129 g          242 t
ORIGIN      
        1 tatattttac acttataaaa tatgaaaact acttattgcg aaagtaattg atttgttgta
       61 ttataattta catgaattat gtaggacaat caaaagtcag tattataaga gtacatatat
      121 tcaaattttt aacaattaat ttatataatt aaaaaatgaa gggtaggatg aagtcatggg
      181 ttttagagaa gtaaaaattg aggaattaca gtttaatcca tttactaaga ttggcaaaga
      241 atggttactt ataacagctg gtgattcaga aaagtttaac acaatgactg ctagctgggg
      301 tggtgttgga gtctattggg gtaaaaatgt tgttacaact tacataagac cacagagata
      361 tacaaaagaa tttgtagata gtaatgatac atttacagtt gccttctttg atgaaacgta
      421 tagagaggct ttaaatattt gtggtactat ttctggtaga gatataaata aaatagaaaa
      481 agcaggactt acaccatatt ttgtggatga tacagtagct tttgaagaag ctaatatgat
      541 tatagtatgt aaaaagctat atcatggtaa tatgccacca gaaaactttg atgctaaaga
      601 aaatgataaa aaatggtatc cagagaaaga ctaccatact atgtacattt cagaaattat
      661 aaaagttctt gtaaaagaat aattataata aaaaatatat gaaaagaact tattataagt
      721 aaatgactgt gctttcttat ct
//
LOCUS       DAMJWC010000183          735 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMJWC010000183 DAMJWC010000000
VERSION     DAMJWC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.188"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..254)
                     /locus_tag="PC503_003720"
     CDS             complement(<1..254)
                     /locus_tag="PC503_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529630.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKIS"
BASE COUNT          300 a          110 c           86 g          239 t
ORIGIN      
        1 ttagatatct taaacttaat gtgaagaatc cctgtaacaa gaccagcagt acaaccacat
       61 aagatagcca ttaaagttgc tactacagga gaaataccat tagtaagaga aaatgctaca
      121 atagaagcac ccattgtata gctaccatca gcagacatat ctggaaaatc taagattttg
      181 taagttatat aaacccccag tgccataatc gataaaatta aactttgcgt cattacagat
      241 ataatacctg acataaataa aacacccctt tgaaaatatt ttaaatggtt tttaaaattt
      301 ggttttaaaa aatgattttg atataaaaaa accacacagt atatataact gtatggcaaa
      361 aattcgaata agccacacag tataatccat gtggctctat attatgatga taaaataaaa
      421 actttaacaa caattactat agccaacata gatacaatcc ttaaaaatca taatcctaag
      481 gggcttgtat ctatgttatg acaatttgtc ttaacttagg tacaaaccct aactaaattg
      541 gctactaaaa aatcgtactt gtttgtttaa taaagtcttc atatttacct ctccttttaa
      601 tttaataatt ttgaaaattt tgttttctgt tttgtatagt aattagttta atacagtaaa
      661 aaataaaagt caactataaa ttttgaaaaa ttatcaaatt atcagaaaat tgagtttaaa
      721 taaaaaaatt tttac
//
LOCUS       DAMJWC010000184          716 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMJWC010000184 DAMJWC010000000
VERSION     DAMJWC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.189"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            100..507
                     /gene="tnpA"
                     /locus_tag="PC503_003721"
     CDS             100..507
                     /gene="tnpA"
                     /locus_tag="PC503_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013824389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDF2529631.1"
                     /translation="MEVTHGRGYVYLVQYHIVWCVKYRHPVLTNEIEEDLINILNKIA
                     EDNKFQILECNSDKDHIHLLINCSPQHYIPDIIKALKGVSARLLMKKHGEQLKKKLWG
                     GHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            509..>716
                     /locus_tag="PC503_003722"
     CDS             509..>716
                     /locus_tag="PC503_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529632.1"
                     /translation="MAVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNNKETFTYKQCSSDLTNLKKELKW"
BASE COUNT          314 a           67 c          117 g          218 t
ORIGIN      
        1 ttgcgtttct tacgtatgtt atttaaaaat aaatataaaa accttaagaa tacttgtttt
       61 aagtaattac tatgttaata ttatgttggg tgatgaaaaa tggaagtgac tcatggtaga
      121 gggtatgtgt atttagtaca ataccatata gtatggtgtg taaaatatag acatccagta
      181 ttaacaaatg aaattgaaga agatttaatt aatatattaa acaaaatagc tgaagataat
      241 aaatttcaaa tattagaatg taatagtgat aaagatcaca tacatttact aataaattgt
      301 tcaccacaac actatatacc agatataata aaagcattaa aaggtgtatc agcaaggctg
      361 ttaatgaaaa aacatggaga acagttgaaa aagaaattat ggggaggaca tctttggaat
      421 cctagttatt tcgttgctac tgtatcagaa aatacagaag aacagataag aaaatatatt
      481 aataatcaga aaaaacaagt aaagtgaggt ggcagtagtg gaaaaagctt ataagtttag
      541 aatgtatcca aataaaaaac aacaagagtt aattaacaaa acttttggat gttgtagatt
      601 tgtatataat aagtatcttg ctaaaagaat agaagtttat aaaaacaata aagaaacttt
      661 tacttataaa cagtgtagtt ctgatttaac caatttaaaa aaagaattaa aatggc
//
LOCUS       DAMJWC010000185          676 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMJWC010000185 DAMJWC010000000
VERSION     DAMJWC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.190"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            33..>676
                     /locus_tag="PC503_003723"
     CDS             33..>676
                     /locus_tag="PC503_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2529633.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIK"
BASE COUNT          240 a           59 c           86 g          291 t
ORIGIN      
        1 aatataattt aatcattttt gaggatatta ttatgttaga tgcatttata acaattgttt
       61 cttctattat agaaatatgg tcatgtaaaa aagtttttga ttatactagt cagtcaaaga
      121 ccgacttaaa aaaactaaat atgtattttc tcttttctgt ttttctcatt atttcttctt
      181 tatatataaa tataggagct aatagtagaa tcttgatatg tatatttgta atgttcgttt
      241 tctataagtc taactataag gttaatatat ataaatgtct ggtaatctca tttttttatt
      301 ggttaatatt aataggtata aatggattaa gtatgttatt agtagcaaca gtaagcaatt
      361 tggataatat gaatgtttta cttagtggca gtttatatag atatgaagca atattcttgg
      421 gaaagataat gttaggtata ttactttatg tttataaggc ttcttttaaa aattttaaaa
      481 taagtaaaaa agagatatac atatgtattc ctatgatagc aaatttattg tcattttttg
      541 tactttatga ttatattatt aatcttgtaa aaatctctcc tgaaagaaga actgcttttt
      601 tagtaatagt tttactatta atattatcta acatttcaat ctttgtatta atacatataa
      661 tacttaagat taaaat
//
LOCUS       DAMJWC010000186          665 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMJWC010000186 DAMJWC010000000
VERSION     DAMJWC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.191"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            49..>665
                     /locus_tag="PC503_003724"
     CDS             49..>665
                     /locus_tag="PC503_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2529634.1"
                     /translation="MTLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPEYLNVWELQ
                     GITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSSPITE
                     LTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNV
                     PNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNG"
BASE COUNT          295 a           93 c          106 g          171 t
ORIGIN      
        1 aaatcaaaag ttagtgtcaa atttaaagaa aaaccagatg cagatagcat tacattaaag
       61 tataaatgct atgacatgcc attgaataca actctaaatt acaatcaatc aactggggca
      121 tatgaaggaa ctatcaatta taaccaagac ccagaatatc taaatgtttg ggaactacaa
      181 gggataacaa taaacagcaa aaataatcct aaaactttaa acagacaaga cctagaaaag
      241 ctgggattaa atttaaaaga ctataatgta acacaggaat gtataattga agatataact
      301 tctagaaaag atgtaaataa atatttgaga aaaacttctt cacctattac agaacttaca
      361 ggaagtgata gatatgaaac agcagttaaa ataagtaaag agggctggaa aaatggttca
      421 gataaggtag ttataataaa tggggatgta agtatagatg gcattatatc aactccactg
      481 gcaaccacat ataatgcacc aatacttttg gttgaaaaaa acaatgtacc taatagtgta
      541 aaatcagaat taaagcgcct aaaccctaaa gatataatta taattggaga tgagaatgct
      601 atttctaaaa ctactgctaa tcaaattaaa tcaactgtaa atgctagtca aacacgttta
      661 aatgg
//
LOCUS       DAMJWC010000187          664 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMJWC010000187 DAMJWC010000000
VERSION     DAMJWC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.192"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..>664)
                     /locus_tag="PC503_003725"
     rRNA            complement(<1..>664)
                     /locus_tag="PC503_003725"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAMJWC010000188          611 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMJWC010000188 DAMJWC010000000
VERSION     DAMJWC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.193"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          244 a           45 c           73 g          249 t
ORIGIN      
        1 cactaaaaat aagaatgtat aaggtggtaa atttatataa aaaagaatat gagttgtaaa
       61 atattaaata atattgtact aattggaata attttaactt tattatagat tattttaata
      121 ccattagtac tgatggtgta ttttaaaatt ggtataagca ttacaaatac gaatatgcca
      181 actgtaatat gtaatataag tagctatata catatgtgct gtcccatata ttgtatcatt
      241 gtttatatta aaaagattat gtaaattggt atcaatcaat aaatcatttt cagaagaaat
      301 acctaaaaac ttaaaaaata cctatatgtg tatttagtta gatttgagat ttttacattt
      361 aattttatag tgacaatatt atattatttt tatgatgtct atttatatgc aattactata
      421 atatcagaac ttatagtatc atttgtttca ttatcaataa ggttttttac tttagttttg
      481 tcaattttat taaaaaaagt tattgatata aaagataaga aggataaaac tatatgacgg
      541 atttcaaaca taagagtgga tatttatata atagatattt tatagttaat tttattagat
      601 tttatttaat a
//
LOCUS       DAMJWC010000189          577 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMJWC010000189 DAMJWC010000000
VERSION     DAMJWC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.194"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>577
                     /locus_tag="PC503_003726"
     rRNA            <1..>577
                     /locus_tag="PC503_003726"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAMJWC010000190          496 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMJWC010000190 DAMJWC010000000
VERSION     DAMJWC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.195"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>496
                     /gene="tuf"
                     /locus_tag="PC503_003727"
     CDS             <1..>496
                     /gene="tuf"
                     /locus_tag="PC503_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2529635.1"
                     /translation="GTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLD
                     QAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFD
                     GYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRT
                     VASGV"
BASE COUNT          213 a           61 c          125 g           97 t
ORIGIN      
        1 ggaacagttg caacaggaag agtggaaaga ggagtactaa aagtacaaga cgaagtagaa
       61 ttagtaggat taacagaagc accaagaaaa gtagtagtaa caggagtaga gatgttcaga
      121 aaattattag accaagcaca agcaggggat aatataggag cattattaag aggagtacaa
      181 agaaacgaga tagaaagagg acaagtacta gcaaagactg gatcagtaaa ggcacacaca
      241 aagtttacag cagaagtata tgtacttaaa aaagaagaag gtggaagaca tacaccattc
      301 tttgatggat atagaccaca attctatttc agaacaacag acgtaacagg agcttgtaag
      361 ttaccagaag gaatagagat ggtaatgcct ggagataacg taacaatgga agtagactta
      421 ataaactcaa tagttgtaga agagggatta agattctcaa taagagaagg tggaagaaca
      481 gtagcttcag gagttg
//
LOCUS       DAMJWC010000191          493 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMJWC010000191 DAMJWC010000000
VERSION     DAMJWC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.196"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="PC503_003728"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="PC503_003728"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="PC503_003729"
     tRNA            310..398
                     /locus_tag="PC503_003729"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
     gene            410..486
                     /locus_tag="PC503_003730"
     tRNA            410..486
                     /locus_tag="PC503_003730"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Ile,seq:cat)
BASE COUNT          156 a           91 c          109 g          137 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgaa tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt ccctgatggc
      481 ccaccacaat aat
//
LOCUS       DAMJWC010000192          387 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMJWC010000192 DAMJWC010000000
VERSION     DAMJWC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.197"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            134..322
                     /locus_tag="PC503_003731"
     CDS             134..322
                     /locus_tag="PC503_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529636.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
BASE COUNT          163 a           28 c           63 g          133 t
ORIGIN      
        1 atgtaatgtc actgatagtt agaatattta agtgctaaaa gatgtgtata aataataatg
       61 atgtcagttt ataatgatat taaattgaga tatactgttt ctctaaatta aaaaataaag
      121 gagtaaatgt gttatgaatt atcatacaaa agaagaattg gtggaagcac tgagagtagt
      181 atcttcaagt attattaatt gtggaaaagg acagaagaaa ttttctgagg agacatctca
      241 tcatacacgt tttaagaata ttatagaagt aatgtatatt tcaaaatcat taataatgga
      301 tgaaattagt aaaagagatt gaagcttatt ttgcaattta acatgtttta atatacattt
      361 tattatataa gaaaataagt aaacata
//
LOCUS       DAMJWC010000193          374 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMJWC010000193 DAMJWC010000000
VERSION     DAMJWC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.198"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..372)
                     /locus_tag="PC503_003732"
     rRNA            complement(<1..372)
                     /locus_tag="PC503_003732"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           87 a          102 c           63 g          122 t
ORIGIN      
        1 aggactatta ccttctgtgg tgggtctttc caaacctctt caattacgat acctcttcgt
       61 tatgatatgt ccgcaacccc aataaagaaa actttattgg tttgggctaa tccgcgttcg
      121 ctcgccgcta cttacggaat cgaatttctt tctcttcctt caggtactta gatgtttcag
      181 ttccctgagt tcccctcatt aagctatgta ttcacttaat gatacttaga cattactcta
      241 agtgagtttc ctcattcgga aatcttcgga tcaaagttta cgtgcaactc cccgaagctt
      301 atcgcagctt atcacgtcct tcatcggctc ctagtgccaa ggcatccgcc ctgcaccctt
      361 aataacttga ccag
//
LOCUS       DAMJWC010000194          363 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMJWC010000194 DAMJWC010000000
VERSION     DAMJWC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.199"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            167..283
                     /gene="rrf"
                     /locus_tag="PC503_003733"
     rRNA            167..283
                     /gene="rrf"
                     /locus_tag="PC503_003733"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            290..361
                     /locus_tag="PC503_003734"
     tRNA            290..361
                     /locus_tag="PC503_003734"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Asn,seq:gtt)
BASE COUNT          116 a           61 c           78 g          108 t
ORIGIN      
        1 ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta ctaacttcaa
       61 ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact attgacattt
      121 aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg gttataatag
      181 caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta gcgctgatgg
      241 tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt ccaaggtagc
      301 tcaatggtgg agcaaccggc tgttaaccgg taggctgtgg gttcgagccc cacccttgga
      361 gcc
//
LOCUS       DAMJWC010000195          313 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMJWC010000195 DAMJWC010000000
VERSION     DAMJWC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.200"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          128 a           31 c           26 g          128 t
ORIGIN      
        1 taaagttatc tatgtactat attaaacaat taagtagtta ttaattgaac ttattagttt
       61 attaaaaaac tatgtatatt actttgcagt aagactttgg aactaaatct ataatagcaa
      121 atttaaattt attaaataga ttaccttata acatttcata taaaatatat tgtgaatctg
      181 agaaaattac tatttttctt tgagtatttt ttgtaagcag ttctaaaaga ttcaatttca
      241 tacctattac ttgaatcatt cattaaaata attctaattt aaaaaataat tctatccaaa
      301 taatagatat ata
//
LOCUS       DAMJWC010000196          301 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMJWC010000196 DAMJWC010000000
VERSION     DAMJWC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.201"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          142 a           24 c           29 g          106 t
ORIGIN      
        1 aaaaaaacat atttagattt taacatctca aaggagtttt caaagctaat atttcatttt
       61 taaataaaaa aataaaatat tagttttgat ttctggttta aattgggtta taataaattg
      121 tcaaattatt tattaatata aaatagacta taaaacaagc aaaaatcata ctattatata
      181 aaagacctta aagatagaaa actacagaaa gaagccaaaa tgtttttgaa aaaaatgaaa
      241 ttttattgca aaaaaatcaa aatgaattta acttaatagt tataatctat ttttagtgtt
      301 a
//
LOCUS       DAMJWC010000197          278 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMJWC010000197 DAMJWC010000000
VERSION     DAMJWC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.202"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          115 a           20 c           28 g          115 t
ORIGIN      
        1 atattattga aaagtaactt ataaaattat atataaataa taaaattaat tttactatct
       61 acccatatat ttagttatat tgcaggcaga atgtggttta ccataaccaa aaggacaata
      121 aaaaatattt ttctatattt ttattatctt tttgtaaaag atttattatt tattgcatta
      181 aattaatagg cagtagaggc atagttgata aaattaatga agaaattaaa cttatgaata
      241 taaatttatt attgagtttt aatattacat ttattatt
//
LOCUS       DAMJWC010000198          232 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMJWC010000198 DAMJWC010000000
VERSION     DAMJWC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.203"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..>232)
                     /locus_tag="PC503_003735"
     CDS             complement(<1..>232)
                     /locus_tag="PC503_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002590471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase dimerization domain-containing
                     protein"
                     /protein_id="HDF2529637.1"
                     /translation="NVIQKIQQLVPPTHPVLGDGILVLTDIKSSPYPGASVVPDYCKA
                     TFDRRLLVGETREGVLAPIQALLDEMMKEDPE"
BASE COUNT           66 a           41 c           37 g           88 t
ORIGIN      
        1 aattctgggt cttctttcat catttcatct aataaagctt gtattggagc taatacgcct
       61 tctcttgttt ctccaactaa taatcttcta tcaaaagtag ctttgcaata atctggcact
      121 actgatgctc ctggatatgg agaagatttt atatctgtta aaactaatat tccatcacct
      181 aaaactggat gagttggagg tactaattgt tgtatctttt ggattacatt ag
//
LOCUS       DAMJWC010000199          219 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMJWC010000199 DAMJWC010000000
VERSION     DAMJWC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.204"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..>219)
                     /locus_tag="PC503_003736"
     rRNA            complement(<1..>219)
                     /locus_tag="PC503_003736"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           42 a           64 c           47 g           66 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtccc
//
LOCUS       DAMJWC010000200          213 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMJWC010000200 DAMJWC010000000
VERSION     DAMJWC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.205"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..>213)
                     /locus_tag="PC503_003737"
     CDS             complement(<1..>213)
                     /locus_tag="PC503_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529638.1"
                     /translation="SLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIKDTTA
                     IIVGSFIYQFTIYFAMSLGMLSTDLKL"
BASE COUNT           83 a           33 c           31 g           66 t
ORIGIN      
        1 tagttttaag tcagttgata acattcctaa actcattgca aagtatatag tgaattggta
       61 tataaaagag ccaacaatta ttgcagtagt atctttgata aaagtaaatt tcttaaatag
      121 tgtaatacca attatgatag aggcaattcc aagaactaaa gttcctatac ccatatttac
      181 atctgagaat cccaagaact gagccataag act
//
LOCUS       DAMJWC010000201          209 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMJWC010000201 DAMJWC010000000
VERSION     DAMJWC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.206"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            73..>209
                     /locus_tag="PC503_003738"
     CDS             73..>209
                     /locus_tag="PC503_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529639.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KS"
BASE COUNT           91 a           25 c           32 g           61 t
ORIGIN      
        1 taaatatttc actaaaaaaa aacaaatgca aagctagtac caaaaataaa tcagaaaaaa
       61 gaggtgttgt agatgttaca aattaaaaat ctttcaaaga gtttccctaa tccatatggt
      121 gaacctaata ctatctttga aaatttatca atcgatatag aagatggtga atttgtaagt
      181 atcataggta gtaatggaac tggtaaatc
//
LOCUS       DAMJWC010000202          206 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMJWC010000202 DAMJWC010000000
VERSION     DAMJWC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.denovo.207"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..167)
                     /locus_tag="PC503_003739"
     rRNA            complement(<1..167)
                     /locus_tag="PC503_003739"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           52 a           55 c           39 g           60 t
ORIGIN      
        1 ttatcccgta ttagcatacc tttcggtatg ttatccgtgt gtacagggta ggttacccac
       61 gcgttactca cccgtccgcc gctctttacc gaagtaaatc gctcaacttg catgtgttag
      121 gcacgccgcc agcgttcatc ctgagccagg atcaaactct caaataaaag tttatcaggc
      181 tcagatacta ttgttatcaa aatatc
//
LOCUS       DAMJWC010000203        18275 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.guided.075, whole genome shotgun sequence.
ACCESSION   DAMJWC010000203 DAMJWC010000000
VERSION     DAMJWC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18275
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.guided.075"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC503_003740"
     CDS             complement(<1..658)
                     /gene="bclA1"
                     /locus_tag="PC503_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HDF2529640.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     A"
     gene            complement(1336..1860)
                     /locus_tag="PC503_003741"
     CDS             complement(1336..1860)
                     /locus_tag="PC503_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2529641.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(1925..2677)
                     /locus_tag="PC503_003742"
     CDS             complement(1925..2677)
                     /locus_tag="PC503_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2529642.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(2708..4006)
                     /locus_tag="PC503_003743"
     CDS             complement(2708..4006)
                     /locus_tag="PC503_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2529643.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4023..6287)
                     /locus_tag="PC503_003744"
     CDS             complement(4023..6287)
                     /locus_tag="PC503_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2529644.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(6542..7360)
                     /locus_tag="PC503_003745"
     CDS             complement(6542..7360)
                     /locus_tag="PC503_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2529645.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC503_003746"
     CDS             complement(7353..8051)
                     /gene="cbiQ"
                     /locus_tag="PC503_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2529646.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8054..8338)
                     /locus_tag="PC503_003747"
     CDS             complement(8054..8338)
                     /locus_tag="PC503_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2529647.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8328..9080)
                     /locus_tag="PC503_003748"
     CDS             complement(8328..9080)
                     /locus_tag="PC503_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2529648.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9262..9454)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9586..11358)
                     /locus_tag="PC503_003749"
     CDS             complement(9586..11358)
                     /locus_tag="PC503_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2529649.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11372..12301)
                     /locus_tag="PC503_003750"
     CDS             complement(11372..12301)
                     /locus_tag="PC503_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2529650.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            12522..12707
                     /locus_tag="PC503_003751"
     CDS             12522..12707
                     /locus_tag="PC503_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2529651.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            12700..13401
                     /locus_tag="PC503_003752"
     CDS             12700..13401
                     /locus_tag="PC503_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529652.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13403..14326
                     /locus_tag="PC503_003753"
     CDS             13403..14326
                     /locus_tag="PC503_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529653.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            14483..15406
                     /locus_tag="PC503_003754"
     CDS             14483..15406
                     /locus_tag="PC503_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529654.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15399..16136
                     /locus_tag="PC503_003755"
     CDS             15399..16136
                     /locus_tag="PC503_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529655.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            16147..16920
                     /locus_tag="PC503_003756"
     CDS             16147..16920
                     /locus_tag="PC503_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529656.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(17461..18069)
                     /locus_tag="PC503_003757"
     CDS             complement(17461..18069)
                     /locus_tag="PC503_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2529657.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5928 a         3133 c         2271 g         6943 t
ORIGIN      
        1 tcgctcctgt acttccggtt gggcctgtta ctcccgttgg tcctgtactt cctgtcgctc
       61 ctcttggtcc cattggacct gtaattctaa ttggaagaca ctcacattta ggataacaat
      121 tatctataat tctatcttca aatgttacaa gtatatacgg tttgttacaa cctctactag
      181 atgtaaattc aagaatctga taagggtaat ttaaagataa agctaaccca taattaggat
      241 atttattcat tgcccatgct tttatagttc ccgtaatatt taaacaaata tagttggatg
      301 tatcacttat cccaactggt aaatatcccc taatattttc catagacact ctatcattcc
      361 atgttatagt tcgtaaatta taatattcac ttattctttt aatttcaata tctacttttt
      421 ctttaaaaat atgattctta tttgaatcaa tatgaataaa taactctgct tttaatatac
      481 ttttgtcttt taatatatct ggtattctca ctttaaaaaa agtaatcaac ttttctttta
      541 caaaactatt tgaacattta cttcctatta agcaataatc taaattacta aagtttttat
      601 ctggatattt tttagatata aaagtatcat catttaaata aagtataata tttctcattt
      661 ataatccctc cattttgggt ctatatcata ctatgtttaa aatacatgct tagttacaat
      721 ataattaaaa tttatagtat taaattttta tataataatg ctgatttcta caaaaaaaga
      781 acatgtcatt agaaatttct aatagcatgt tctttttcat tattatatat tacactttaa
      841 attattcctt gactggctta gctggtgtaa actaaaccag tctttctaaa atattaagca
      901 cttttttctt attatgtttt ttaggattta ttgtctatat tattgtaaac caaagttata
      961 aaattgtaaa tagaatatat taccataaca atatcttttt ataagtaaaa attataaaaa
     1021 accttatttt tattaaatag aataaataaa ataagtttaa aaaatactga aataagtgtt
     1081 ttccacatat tttatatatt tatttaatac attattattt aaaaataaat atataaacaa
     1141 tcataataaa atttttttaa taaaacttta ttttttagtt aaaatcatac aatatataga
     1201 tttccacaat acaaataaat taaaaagtga aatgtatttg tctaaaaaca taataacatt
     1261 tcactttatc ctcattttta agtaatatat atttttaatt tttatttata actaaatcta
     1321 gtttttatat aaattttagt ttttttctac atctgagtaa tctattccaa aagtttctac
     1381 agtaacagat ttcataactt gtggagtttg tggcttatca gctgaatctg ttctaactga
     1441 tgctatttca tcaactgtat ccataccttc tatcactcta ccaaaacctg catactgacc
     1501 atctaagtgt ggtgagtttt tatgcattat gaaaaattga gaaccagctg aattaggtgc
     1561 catagttcta gccattgata tgactcctct ttcatgtttt aaattgttag taaatccatt
     1621 accactaaat tcacctttta ttgagtgacc tggaccaccc attcctgtac catttgggca
     1681 tcctccttgt atcataaatc ctggtattac tctatgaaat attattccat tgtaatatcc
     1741 ttcatttact aatgatacaa agtttttaac tgtatttgga gctatatttg gatataactc
     1801 aattttgatt tcttttccat tttccatttc tatagttact ataggatttt tattttccat
     1861 aatttattac cttccttttc attagttaaa ttacataatt acatttatta tattatactc
     1921 taaattaaag tctatcaagt atattttttc ctatttcata tccttcttga taaatagttt
     1981 tacaaaactc atcatcaaag ttaagcgtgt ctttaggagc aaattgagta ttaggtctaa
     2041 ctactattat tttatcttca tcatatactt ttttaatatc ttctggcaac tcataattat
     2101 attttgtgga tattaaaata attttatcca cattatcccc aattaatggt tcaattaatg
     2161 cactcctaat taaacctcca tctaatttga aaccatcata aattccttct tgcacatctt
     2221 tcacaaattg ttctttaaat ccaagagttg cgtttggatt tgatggtaac aacccactgt
     2281 atgaaatgct gataatggct tcattacgag gcatttttga tacgtcaaca atcttttctg
     2341 atactacttt attatcaact tcaacataat taacataaaa gttcatttct tctatattac
     2401 tatcatctag ttcccttagg ttgtctatag caggagaatt atccacagta ttatttacta
     2461 tttttacatt tccattctgg atatctttta tatttgtcca cattttctcc aagttatcaa
     2521 cattccctgt gtacaaataa tatccattta ttgctcctat tgatgtccct gaaatcgaat
     2581 aaaatttatt tattcctcca tcatacaagg ctttaactac tcctgcttga taagcccctt
     2641 ttgctcctcc accttctaaa cataatccta atttcatagt ctcatctcca aattgtttat
     2701 cttatattta tatttcaaaa aacttactaa atgttttata tatactatag tggtcctcaa
     2761 catttcctaa ttctcttata gaatgcattg ctaaaattgg acttcccaca tccacagatg
     2821 gtatatctat atgagtagaa gatattggac ctatagtact tcctcctctt tcatctgacc
     2881 tattaacaaa ttcttgatac tcaacattag cttctctaca tatattttta taaatagcta
     2941 tagaatatcc atcactagta tatgcctgac tagcatttat ctttataacc ggaccttttc
     3001 ccattattgg tttattagtt gggtcatgct tttctggaat gtttggatga atagcatgag
     3061 ctaaatctga tgatatcata aaagatgaat aaatagactc aaagaatccc tctctatcct
     3121 tacccattga tatgcaaatt ctctccaata tatttaacaa catgtttgaa tctgcacctt
     3181 gtttagtaga gctaccaact tcttcattgt caaatacagc cattacattt acaccatgtt
     3241 gacctttagt attaacaaga gcattcaaac tagcatgtac cattgcaaga ttatcttgtc
     3301 tcccaataga tataaattca tcattagccc ctattaaact tcctttttca aattcatata
     3361 aaaataaatc aaaatctata atatcgtcca tatttacatc taagttagat gctatttgct
     3421 ttataagaaa attatctttt tctaatgtat catttaacat cccaactaaa ggtaacatat
     3481 ctttttgctt attatatgag tgaccatcat ttatacttct atttaaatgt attgctagat
     3541 ttggtattat acaaattggc tttttaaagt ctataagcct ttcatttggt tttaatatac
     3601 tatcaccttt taaaactact ctaccagcta tcccaagagg tctatccaac catgtactta
     3661 atattgctcc tccatagcat tctgtattta acttcaaata agatttttca gcttctattt
     3721 ctgcatttgg tttaatacta aatgtaggag aatctgaatg agagcctatt attctaaatc
     3781 catctctttc tataccttct gaatttacta caaaagctac tatagctgat aaattcttag
     3841 taacataata ctttccacca actcttagat tccatctttg attcaaaact aattcttcaa
     3901 atccattttt atctaagatt tccttagtac tctcgactgc atgaaaagac gacggactat
     3961 catatatgaa gtctattaag tttttagcaa agtttatact atccattcct catttacctc
     4021 cattataaaa tatttagtgt tgtatattct ttatttattt ttttaattcc ctgttggtca
     4081 aaagctatag taacatctgt accaattata gaaaccactg tcccaacccc aaatttagga
     4141 tgatgtacct tagaaccaag ttttatatca tctggattag tttctttatt agaatctttt
     4201 attgtagcat taactttatc tgcaacttta gatttgctta tagtactcat atacttttta
     4261 gtatatttat ctaacatatt ataacttgct ttagaatagc ttagttcttt ttttactttg
     4321 tacaatcttt ctatacattc ttctggcagt tcttccataa atcttgaagc tattgcaaca
     4381 tttgttttac catataatgt tctcttctct gtcaatgaca tatatagctc ttctttagct
     4441 ctagttatac caacataaca aagtcttctc tcttcttcta tttgtgaatc actcatagat
     4501 tttatagctc ttgatatagg aaataaccct tcttccatac ctgttaaaaa cacaacaggg
     4561 aactctaaac ctttggatgt atgaattgtc ataagcgaaa ccctatcatt gtcttcttca
     4621 tcatttgatt cagatgtaag tgctatactt gttaggaatg tctctaagtc tttattttca
     4681 taagtatcat cattactact ttcaaactcc aaagctatag aaataaattc tctcaaatta
     4741 tcaattctgt cttgagcttc ttcacctttg cctgttaaat ctttttcatt tttatttctt
     4801 atctctacaa gctcgtccat atatcctgta gtatccaaga ctttttctat aagtttgcta
     4861 acaggataaa cttcttttat agttctaaga gtccctataa tatcaacaaa tccacttata
     4921 cttgcccttg ccttagtaga tatatctgaa tttgtttcta tatcaattaa tactgagtat
     4981 atactttcct gttttaagtt agctctatct tcaatttttt ctatagttct aagccctata
     5041 cctcttctag gaacatttat aatccttttt atagatatat catcttgtgg attttgaata
     5101 actcttaaat acgccaacaa atcctttatt tcttttctct catagaattt tgtaccacca
     5161 tatatattgt atggaatttg acttctattt aaagcgtcct ctacaggtct tgcctgtgca
     5221 tttgctctat aaagtactgc aaaatcctta taaggtctat tttcttttct agctatttgt
     5281 gcaattgaat cagcaatgaa atcagcctct tctatttcac taccagttaa ttgtatcttt
     5341 ataagttctc cttctttttt ttcactccaa agcttttttc tttttctttc tatattatta
     5401 gatataactt tattagctgc atctaatata acttgtgtag acctataatt ttgttccaac
     5461 tttacaacat gtacattgtc ataatctttc tcaaattcaa gtatgtttct tatatctgca
     5521 cctctccatc cataaatact ttggtcatca tctccaacaa cacaaatatt ttgatgttct
     5581 cttgctaata attttatcaa ttcatattga gctttacttg tatcttggta ctcatctacc
     5641 attatgtatc taaatctact tctgtaatat gctaacactt catcattagc cttgaaaagt
     5701 tctacagttt taagtattaa atcatcaaag tcaagtgcac tatttctttt taaacggtct
     5761 tgatatagcg cataaatatc tgcaatctta accattctat tatctgccat attgatatct
     5821 ttaaactgct ttggagtata aagtttgtct tttgctcctg aaattgcact tataactgct
     5881 tttggttcaa acactttatc acttaaattt aattctttta gacagtcttt aaccaatgta
     5941 acttggtctg ctgaatcata aattacaaaa cttctattgt aaccaatctt atttatatct
     6001 tttcttagta tacgaacaca gcaagaatgg aatgtactta tccacatatc cttagtttca
     6061 ggacctatat tttgttcaac tctctctctc atttcatttg cagctttgtt tgtaaatgtt
     6121 atagctaata tatttggtgc ttgtacacct ttatcttcta taagatatgc tattcttgtt
     6181 gttaatacct tagttttacc tgaaccagca ccagccagta taagtactgg accttcagtc
     6241 ttttctactg cttctctttg agcaggattt aatgtatcta aattcatatt tctcctcctg
     6301 ttaacagcca taaatatatt ttaatctaaa atatgaatta cttcaaatta taattatgta
     6361 ttatattaat agattatttc caatatatta caattaaata acatttttcc atataattta
     6421 tttcattgtt taataaaaaa aataacctta tgatttgggg aatcataagg cacctttaag
     6481 gggtctaggt taagggttat tatatataaa tctatttttt taaaataggt ttagggctta
     6541 attatttatt tgtattaagt tctctttcct tccaatactt atacaaatct tcttctttct
     6601 taaataaggg taaattcata tttctatgta cttttactaa ccatggggat tctaggccag
     6661 cttgtataat attattttca tttataaaca cattttctgc ttttccttca tcaatcaaaa
     6721 tccccttatc caatacatat atgtaatcac atatttcata cattaaattc atatcatgac
     6781 tggatattac tatttttata ttatttttat ttaatccctt tattatatct acaatagacc
     6841 tagtacttac tgggtctaaa ccagctgtag gttcatcaag taatacaatt tcattttcca
     6901 ttgctataac tgatgctatt gccactcttt ttttctgtcc atagctaaga aaatgtactg
     6961 gcctgtctat aaaatctatt ccattaacag ctactagagc tttgtttatt ctctctttaa
     7021 ttgttttttc atccatacca atgtttctca ttgcaaaggc tatatcatca tatacttttg
     7081 aataaaaaat ttgtttttct gggtcttgga agacaatacc tacatttttt ctaaggttgt
     7141 ataaacttct cttatcatat tttaactttt cttctttaaa aagaatttct ccagatgtag
     7201 gctttaatat acccattaaa ttcataaata atgttgattt tcctgaacca tttgaaccta
     7261 ttatacctat aacatttccc tttgaaaaat ccatattaat gtttaatagt gcattggtat
     7321 ttttttcata ttgatacgtt aaattattta ttttaaacat cattatcccc tactatgtga
     7381 aatttaccat catacaattt tatgtctaat gatatacaca tatcatcata ccttgtcata
     7441 agtcttttgt acagcatact tccaagaata cctaaggatt tatatgaagt ttttaaattt
     7501 atatatccaa atcttagctc ttgtgacttg tatatttctg aaaattcttc taaaaatatg
     7561 aatataaacc tatatattaa cattgataac tcgacaaaag tgtcaggtaa atgaagtttt
     7621 ttaaaaaaga atattaattg attaaaaggt gttgtaagta tacaaaaata cacacaagtc
     7681 aaacaagaca tcgctctaaa taacacatga atagacatgt taatagacgc ctttgatatt
     7741 cctacattaa aactaaaaaa ttcaaaacta tataataaat ctgctttatt aaaagatata
     7801 tttacaagag ttattcctat actaagaaat aaaaagtaca ttggtattct aagtaatttt
     7861 aaataatttt ttaaatctat tccagccaca caaacaacca aaatactcat taaaatcata
     7921 attccactta aaataaatat attttgtatt accatagaag caatcagaaa aattactcct
     7981 atggctactt ttttgtttgg atttacttta ctcaatctat ttgtatatgc atatttatca
     8041 attataagca tgattaactt ctctttcctt tttgaagacc taatatgtat cctattacac
     8101 cagcccctaa agctgcttgt gcagagaata ataaactttc tatttctcca cttggtggct
     8161 catatggact gctaaaccat ggtttgtaat ttggatttat cttagtaatt tcactttcag
     8221 cttgaccatc tgctcctcca tattcagcac ctgagttgac aagtaatggg aatataataa
     8281 gagctactac taataaaagt aataatatgt tagtttttgt ttttgtttta gcactcatta
     8341 gctttaactc ctttatcatt attttctagt atgctttttt ctccgttttc tgtaattaaa
     8401 ttatatacaa ttacagtaag tataccttct gctattgcta ttggtatttg agtcataaag
     8461 aaaattccta aaaatttaat tgctgaagcc attaccccac ctgatgggtc tgggaaagcc
     8521 agtgctaatt gtattgaagt tattgtatat gtggctaagt ctcctattgc tgctgcaaga
     8581 aatactggaa tagcattatt tccatctttt ttctttaaag ccttaaatat taggaatgat
     8641 acgattggcc ctattatcgc cattgaaaaa gcattagctc ctaaagtagt tattcctcca
     8701 tgtgctaata acaatgcttg gaatattaaa actatagttc caagaacaaa cattacgctt
     8761 ggtccaaaca ttattgctcc aagacctaca ccagtaggat gtgaacaact tcctgttact
     8821 gaaggtattt ttagtgctga taatacaaac acaaatgctc cacataaagc taataatact
     8881 ttctttttag ggtcttgctt tactatttta cctattgatt ttaatccgaa taagaaaaat
     8941 ggtataaata taactcccca tgctatagac cattttactg gtaagtaacc ttccattata
     9001 tgcattgcat ttgatgtaac tggagttaaa atgattaaca taagtgcagc tataacccct
     9061 aatttaatat tctgtttcat cttagtatcc ctctctccct ttctaataat taaaacataa
     9121 taatacatgt ctgatttatt taataaaata aaaaagccta actcgatggt taggcttcta
     9181 attttccaca atctaaatac aaacacataa aacaaacata tctgtataat tattataaga
     9241 aactttctcc atccccgaag aaattacttt aatattttag gcaggtctcc tgacttagct
     9301 tcatcctact ccttttcctt cccatgagat ataaaaaata tcatcatagt ggctaacaaa
     9361 agtttcgtct gcatcacagt agcgggggct gtaaaggaat ttaacctttt tccctattaa
     9421 tcttgcttaa agaacctata atattatata tttaattttt aaattattct taaatcattt
     9481 tctatataaa tcattgtata ccttttctgt gaaaatttct acatttttta taaattttat
     9541 tcatttttat atttttatgt atataaattc ttttttgtaa gtttattaat ttctaattat
     9601 cttctttaaa tacattgaaa ctacatcaga aaatctagtt atatctcttg aatatataaa
     9661 atcatttcca tatattaatc tttcagcttc aagttctgat tcttttcctg taaatactcc
     9721 taatactaat atattttgct ttctagcttt tctcacttca ttggctgtat ctctcaaacc
     9781 aactataccc ctataagcct tttctcctct taatgttctc tcactacttt ttcctatctt
     9841 tacatcattt ggtcttccat cgctgagaac tatcaggatt ttattttctt catctctatt
     9901 tattagacca ctacatatag attttattgc caaaccatct ctattattac cagcacaaaa
     9961 atattcaaat atattttcac tattttttat actatcatca taatctttaa atctttttaa
    10021 tattgtatag tctaaaaaac tagaaaatcc catcactcta tttggtatgc caacttctgt
    10081 tagagcattt gcaattatgt aagcttgaat tgccacattt ccctgatttc tactttgaga
    10141 gccacttgca tccaataata tatcaataac gtatttccct ttttcatttt ctatatcttt
    10201 ataaaatatt ttattattat tacttctacc aactctccaa gctctattgg ctaatatagt
    10261 accacaatca gaatatactc tacttttagc attttcttct attaaaattc ttgacagact
    10321 ttcttttaat ctctttattt gctgtctata cattctagca tgttctctaa attttcctaa
    10381 attattttct ttttgtcttg ttacatattt tagttgaaat acattattac actcacttct
    10441 aagaactcca tctgtaaagt gtattctaca accttcatga acatttctac aattttgtgt
    10501 ctcaattttt ttaatttcac ctttactcaa ataagttttt ccataataat gttctatttt
    10561 tgaatatatc ttatttgcag tgtcttcatc aacatatata actcggtctg ctgaattgct
    10621 acatttagaa tcatcaaaat cccctacacc ttctacaagc atggatgaag atattgaatc
    10681 tatatcactt tcaataatat tttcttcttc atcactataa agttcttcat acatgaaatc
    10741 agcaaatgta tcaaaattta cttctacact ttctacatta ttttcatcaa taagactatt
    10801 ttcttctcca tttaatatgt attcaaaata agttaaatat ataacatcta atgcttttaa
    10861 aatctccata atatcttgat tggtatctat atttcttata tcattaacta ttcttctagt
    10921 catactatct aatgctgggt gcttgtccat actataaagt acaaatgtgt atttaatttt
    10981 atccataata ttatcattgt gtattttggt aaaacgtgaa acaatatctt tataagcatt
    11041 ccttcttatg tcttctatcc ctggcctgtc tttaatgacc ttttcttcaa ctattgtatt
    11101 taatataact tgaattagac ctagtataac atctttgttg tatccttttc ttattctatt
    11161 tgtaagatat tttttaacta tatcccaatc tacatacttt cttctagcac ctgcaattat
    11221 tgcgaaatat agacctattt cttttgaaga gtaatctttt tctgatatat ctatactttc
    11281 attgtaatca ccagctattg tccatgatag gttattagct ctattttcaa attcataatc
    11341 atcatatatc catttcataa tctcacctat attaaatatg acttattgga aacacatcta
    11401 tactctccca tttattaggt attctagttt taattacatc tccaaccatt tctttctcat
    11461 atacatcaaa agtctttcct gtaagtccca tattaattgc aagagttggt tttaatcctc
    11521 ttcttatagt cttaagagat gccataagac cacgtaaatc aatagcttta ctagatatct
    11581 ctccattttg agacttcaat tgtaaatcta aaaatattcc tgcaaagtgt attaattttt
    11641 cttcatcagc atctgaaaat tcatttttta aaatcatcat taacttatct tcttctatag
    11701 gaggaatatc tattaccata aatctagata ccagtgcttc attaagttct tttgttcctg
    11761 catattcata attcatagtc ccaataaatc ttgttgctgg atgtagattg actctctcat
    11821 acccaggtac atcaattatt cttctatagt ctaaagctga atgtaccaca actatagcat
    11881 cattttttgc catattaatt tcatcaaaca ccccaaaacc tccattaata gcacactcat
    11941 aaactgagcc tcttctaagt ttaacttcat tgtctataaa tgtatctgta cctataagtg
    12001 ttgaactgtc tgtatttata tgaaatgatg tattccactg aggtctatta aatatttccc
    12061 ctagattatc agcaagtaag ttttttcctg ttgcctttgg tcccgataat aatatatttt
    12121 cttcttctaa aatagctgct atacacatag acaagatatc tttaccataa aaataagttt
    12181 tagactttgt tactctgtat tctaaatctt tttctaaacc ataataattt ctaaaataca
    12241 gtacatcttc aataagtttt tcatctaccc cttgcaccct tagattatct attatatcca
    12301 tatttttacc ccttttatat aaatagtatt tgtttcattt cttatcacca ttttagcata
    12361 aaaggatata agctaaaatt gattttttaa tctccccatt ttaagtaaaa ccatgcacca
    12421 ttttatcact acaaaattaa gagtactact tactgatatt tcttgatttt gttcgtctat
    12481 acgtatataa tatatgctga taaattatga ggaaaggatg attgaaatat ggatgcccag
    12541 aagtagcaaa aaaatggggt atttctgaaa gaagagtaca aaaactatgt gaagaaagtc
    12601 gcataccagg agtttcaaaa ctcgggtata tgtggctgat accaaagaac gcagaaaagc
    12661 ctgttgatgg tagaacaaaa agaagaaagg aagtacaata tgaatagcgt tttgattata
    12721 gatgatgaca aagaactttg tgctcttatg aaaaaatgtg ttgagcaaga aaatttatct
    12781 gctattactg cacattgtgg tgcagaaggt ctacatttgg tcgataaaaa tagacacaca
    12841 ctctctcttg taattttgga cataatgatg ccagatatag acggttttca agttctgaaa
    12901 aaaattagag aaacaagtaa tattccagta attatgctta ctgctaaaaa tgacgaggat
    12961 gataaagttt ccggactacg tttaggtgct gacgattacc taacaaaacc gttcagcata
    13021 aacgaactta tggctcgtgt caattctctt attcgtcggt atactatgtt aaaccctgct
    13081 tttataacag acacagattg cataataata aatggcatga ttattgacaa gacaaaccga
    13141 attgtttctg tcaataatat tcctgttcaa cttacaagca aagaatttga tttacttgct
    13201 tttctggctt ctaataaggg acgggtgttt accaaaaaac agatttatac acaagtatgg
    13261 gaagaagaat atgcttttga cgatagtaac atcatgtctt tcatcagtaa attgagaaaa
    13321 aagattgaac cagaccccaa ccatccattt tatattttga cagttcgtgg tgtcggttat
    13381 cgttttaata aggaggctta acatgaatac aagtgtctat ctgcttttga tattggttct
    13441 tagcctgatt attatagcgt accttgtttc tgtcctgcta cgtgtccgaa tacaacttac
    13501 acttataaaa gatgctttag aggatataaa aaatggaaac cttaatcgac gtattttaac
    13561 agatgaaaac gacattacaa aacaaatttg ctatgatatt aacgaaatag caatcaatag
    13621 ccaatttcaa cttattcagc aaaaacaatc agaacaagcc tacaaacagc taatgacaag
    13681 tctctcccat gatgtaaaaa ctccacttgc ttctttggtc ggttatttgg aagcagtaga
    13741 aagtaaaatt gttgtaggag aggaaaaaga cgagtatatc catgttgcgt ctaataaggc
    13801 tcattactta aagaattttg tagaaaatct atttgaatgg gtaaaattgg attctaagga
    13861 acaagttttt cattttgata tttttgactt gaatgaatta tcccgtaata ttatatctga
    13921 ttggatacct gttttagaaa gcagtcattt tgaatatgaa tttgatatac cagaaataga
    13981 gtacttctta cgtatagacg caaatgcata tacccgtatc attaataacc tattacaaaa
    14041 tattattacc catagtagtg gcaacaaaat gacattgaga atttttgaaa acaaagagca
    14101 agctcaaatt ataataacag ataatgggaa aggtatatct tcagacaatc tcccacatat
    14161 ttttgaaagg ttgtaccaat gcgaccattc acgagcttca aagggaaatg gtttaggctt
    14221 ggcgattgca aaggaactta ttaacgctca taagggaaat attaccgcca acagcactcc
    14281 cggtatggga acagaattta caatattgct tcctaaagcc ctgtaaaagt acgaggcttt
    14341 cttactctaa aacaagataa aagcaagatt atggcaaggt tttggcaagg ttcatgtttt
    14401 ataattctaa ttgtagttga ttttgacgtt gtatcaacta tcttttgtag aaacaaattt
    14461 attaaaagtg aggaaattat atatgaatga ttttgtgatt gaaacaaagc aacttacaaa
    14521 aatttatggg aatcaaacag tagttgacaa agtcaatctc catgcaaaaa aaggccgaat
    14581 atatggtctg ttaggacgca acggagctgg gaaaaccaca attatgaaaa tgattttagg
    14641 attgacttca atcacgtatg gcgaggtaga tgtatttgga gagaatatta agggacgtga
    14701 aaaacaagta tatccccgta tcggtgcaat tatcgaaacg ccaggatttt atcctaatct
    14761 gacaggaacg gagaacttgg agatttttgc aaaactgcgt ggtacagccg cccctaattc
    14821 tgtaaaaaga gcattggaaa ttgtaggctt accttataaa aataaaaagc tgtttagtga
    14881 atattcactt ggcatgaaac agcgacttgg tattgccaac gctatcctgc atgacccaga
    14941 actgttagtt ttagatgagc caaccaatgg tcttgaccct attggtattg cggagatgag
    15001 aaagtttatt agggacttga gcgttgagca tggaaagaca attcttattt ccagtcatat
    15061 tctttcagaa atctcattgt tggctgatga tattggaatt atcgaccacg gtgttctttt
    15121 ggaagaaagt agtatgagtg aactagaaaa gaaaaacagt aaatatatcc tgctacaagt
    15181 ttcagatatt ccgaagacat cacttatttt agagcgtcaa tttaacacga aggattattc
    15241 cgttcaagat gactacacgt tacaccttta taacactaat ctggatatgg gtgaaatcaa
    15301 taaagcactt gtaatgcaga atgtaactgt tattagttct caactttgta atgatacttt
    15361 agaggactac tttaaaaaaa tcacaggagg agagggcatt gcttaaactt attcaaacag
    15421 aatttcttaa actgcgtcgt aggaaactta tttggctgat gttgttgtct gctctcatta
    15481 tgccgttttt cgcactacta tacttcaatt attttggtaa aacaggtgtt gagccaataa
    15541 agttttataa atggtctgca tttggttata cactttggat tattttgcct gttgttttgg
    15601 gtatattttg caccatgctt atacacgaag aaaaccagta tgatatgctc aaacagcttt
    15661 ggattgtacc tattagtaaa atgggatact tttttagtaa atttttcgtt gttttgattt
    15721 actctatttg ttttatgctg attacagccg ttgcttctgt gttatttagt gtactttctg
    15781 gatatgtcgt atttagctgg gcaagcattt tatatttgtt gaaaaaatgt ttagaaattg
    15841 gtgtaatcac tgcttttgta atgttgccga ttttggcaat cgctacatct caaaaaggat
    15901 acattctccc aatttgtatc acattggtat atgccttttc cggttttgtt ataatgacaa
    15961 taaatatgta tttacaccca ttatccagta tgggagttat tatcatgaga aataaagaca
    16021 ttccaggtct tatattttca caggaaatta atgtcccatt agcatttctt tgtatttgta
    16081 tttggagtat tgtatcagta ttgtttgcaa acactgcact aggaagaaga aagtgaggtg
    16141 tagataatgt ggaaattact ttgggctgaa tgtcaaaaaa ttcgtcgttc aaaaattgtt
    16201 tggattacag tttttgcatc cattatgata gcagtcatag tttttgcagg agggcaggat
    16261 gtatataatg acccagattt acattatggc ttaaagagcg tttatgacgg ttcacggtat
    16321 atagacaatg caggttggta tatggacgca gtacaacctt ggtcaacttt ttttgttctt
    16381 cctgctgtca ttgccctatt aggaagctat attatttgtc gtgaagaaga ggaggacact
    16441 attaaatccc tgcgtcttat tcccataaat gaaacaaaat taaccatagc aaaaatgatt
    16501 attactttta tattcagtat acttctttat ttgttactct ttactataac atttttgact
    16561 gaatccgttt tacatttttc cgatttatcg acaaaactgg ttttaagttg catgaaagag
    16621 tattttcttg atggcatagg tgtattcttt gcaatttctc ccattattgc cttggtatcg
    16681 cgcatgaaaa aaggatattg gcttgcatta gtattcacag aagtttattc tattgctgga
    16741 ctatttgcgg gtatgtcaaa tgtcttacaa accttttttc ctattgcggc aatatttaat
    16801 atttctggat actatataac tactggagaa aaaattatgg ggagtatcat aagtttatta
    16861 ctttgtgcct gcctttctgc atttatactt aaagggctaa aacacaatga aaaaaattga
    16921 aataggtata tcaaaatgaa aaagataaaa aaactgatta ttctaattgt attcttgttt
    16981 ctttttggca tgttacactg ttatactgaa tggaaattca acaataaccc acctaaaggg
    17041 gtaatagaaa gaataaatga atggactgat aagattggac tggattagta acttatgtta
    17101 attatagtga atgtaatatt agcaagttat tgtttcgtat tttaatacta taactttaaa
    17161 tatttggttt taatcttcca aacgaatata aaaaaactgt cacagaggca acatattttt
    17221 gaatatttat aaagtggtag ttttgatttt caaagctgcc gccttttctt ctatataagc
    17281 aaacttatcc tcaacaaagt gtaaaacatg gtacatttta agaaaaaagt accacagaca
    17341 caagcaataa aagaaacgcc gagaacctac aaaaacgtag tgcttatgca gatttacgac
    17401 gccttctatt ttctcaaccg tcttaatgac cttgtacaaa agaaattttt ctaatatttt
    17461 ttataatctt atcttgtgat gttttttatg tataaatgac ttaataacaa atccaataaa
    17521 aattatggat attggtataa ttagaacgag gaatttataa tcattataat gtgacattat
    17581 tcttacccaa ctctcagaaa aaatatatcc tatactgatt aatgaagtat tccatatggt
    17641 tattcccacg atagatgata ttacaaaagt tataatattt tgacctgcta tacctgctat
    17701 aaaagatatg tatgttctac ataaagggat taatctacat acacaaacag aaatagaaga
    17761 gtatttgtta aaataatctt gagatgcaaa tattcctttc tttgcctttg gacatatctc
    17821 tattatttta tttatgatag atttacctcc ccaatttccc actgtataac aaaatatcga
    17881 accaagtata cctgcaatta tacttaaaat taaaattgtc agaaatccaa aatgatttct
    17941 tgcagcaatt gctccacata aaggtaaaac aacttcgcta ggtaatggaa aacaagcata
    18001 ctcaatcata attaatacaa atacagagat taatccatat tgtaaaataa aactattgat
    18061 tacagacact tacttatcta tctcctttct tatttaaagg ttttaagggt acatgttcta
    18121 aggattctca ccctatattt aaagaatcaa tctctttaaa ctattatatg tatttacaca
    18181 aagcatttat aacatacttt aaaaatagta ccttaaaata agaaacttaa taaataaaaa
    18241 aagattacgt ggctacgtcc tactctccca ggcag
//
LOCUS       DAMJWC010000204        16275 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.guided.082, whole genome shotgun sequence.
ACCESSION   DAMJWC010000204 DAMJWC010000000
VERSION     DAMJWC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16275
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.guided.082"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            246..863
                     /locus_tag="PC503_003758"
     CDS             246..863
                     /locus_tag="PC503_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2529658.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="PC503_003759"
     CDS             971..3502
                     /locus_tag="PC503_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2529659.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="PC503_003760"
     CDS             3936..4637
                     /locus_tag="PC503_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDF2529660.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="PC503_003761"
     CDS             4687..5769
                     /locus_tag="PC503_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529661.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="PC503_003762"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="PC503_003762"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2529662.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="PC503_003763"
     CDS             7127..7933
                     /locus_tag="PC503_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2529663.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="PC503_003764"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="PC503_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2529664.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="PC503_003765"
     CDS             10403..11023
                     /locus_tag="PC503_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2529665.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="PC503_003766"
     CDS             complement(11189..11725)
                     /locus_tag="PC503_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2529666.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="PC503_003767"
     CDS             complement(11838..12512)
                     /locus_tag="PC503_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2529667.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="PC503_003768"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="PC503_003768"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2529668.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..16117)
                     /locus_tag="PC503_003769"
     CDS             complement(14681..16117)
                     /locus_tag="PC503_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2529669.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
BASE COUNT         6209 a         1774 c         2723 g         5569 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattatat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggc catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgggt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt ataaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt atctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtactgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tataggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acgatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggat
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc tacctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaga ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttgc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggcgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttatta
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactttatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaatgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagaa
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgtc gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat acttttttca atattaatca gagggcaaaa gcatgcaatg ttttcaccct
    14641 cttgattatt atggaatagg ataagtagaa ttttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagactac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagta agtttccaaa catatctaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga aataattcca tctgaaactg tattaaaaag acctagaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctatcaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgcctttta atatttccaa agtatactat ctttggtgaa atagtagtct
    15601 tcaccttgtt ataaaataat ttaggtagaa aatagtctat ccaacacaaa agtttaactg
    15661 caaagttttt gatgatagag gatgtacaat ttggcatact tgtggaaaat aaatctaaag
    15721 tatttttaaa tgcaatcttt ttagtccaat ttaaggtgtc attttctatt ttacatggaa
    15781 agtcgatatt atataaatcc caactgttaa acttagaact attataaata ttaaaaattt
    15841 taagcatctt atctgtttgt tctttgtcaa aatttatttt tagattgttt aatctaatat
    15901 agggaattgt aggattatta aaaaaataag tatctatatt tttaattttt tctatgtatt
    15961 tatcaattga atcatcaaca cctatatatc ttgtaaagta gacttcttta atatatgaag
    16021 aactcttatt tttataggta gtatcagata taaattcaat tagaggttca gtagactttt
    16081 ttattgaaat ctttaatggt ttaatagtac aaatcatatt ttttctccta taataagatg
    16141 atataatcta ttataaaaca acttaaaaca atatagtaca ataattttgt agtttcaaaa
    16201 taaaatatgt acttgtttat ataaatgata tataattaca ataaaattgc cgaaaagccc
    16261 tctcctttag gtgta
//
LOCUS       DAMJWC010000205        15199 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.guided.091, whole genome shotgun sequence.
ACCESSION   DAMJWC010000205 DAMJWC010000000
VERSION     DAMJWC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.guided.091"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="PC503_003770"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="PC503_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2529670.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="PC503_003771"
     CDS             1575..2258
                     /locus_tag="PC503_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529671.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKQFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="PC503_003772"
     CDS             2255..4915
                     /locus_tag="PC503_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529672.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="PC503_003773"
     CDS             complement(5096..6277)
                     /locus_tag="PC503_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529673.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="PC503_003774"
     CDS             complement(6277..6939)
                     /locus_tag="PC503_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529674.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7071..7709)
                     /locus_tag="PC503_003775"
     CDS             complement(7071..7709)
                     /locus_tag="PC503_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2529675.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="PC503_003776"
     CDS             7888..8493
                     /locus_tag="PC503_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2529676.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="PC503_003777"
     CDS             8997..9746
                     /locus_tag="PC503_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2529677.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="PC503_003778"
     CDS             9743..10507
                     /locus_tag="PC503_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2529678.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="PC503_003779"
     CDS             10606..11427
                     /locus_tag="PC503_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2529679.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="PC503_003780"
     CDS             11441..13105
                     /locus_tag="PC503_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2529680.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            13110..14984
                     /locus_tag="PC503_003781"
     CDS             13110..14984
                     /locus_tag="PC503_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2529681.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5710 a         1744 c         2525 g         5220 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acaatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataaa
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcaattagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggt tgactgaaaa agatgcttca aaagaacttg cgaaaaatgg
     3901 aggatttaaa aatatagctt catctaaaaa gtactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttatga tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtgcagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaggtaa
     5701 ttggagtctt aagttgatga gcaatatctg caaggttatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatac aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ttgtcctcca ttctatatcc
     6301 tatgcctctt aatgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggattgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca ttatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttc atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatatttatg taaatataat atttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagatgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatgatgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 gtagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 aattttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtagtagtaa
     8701 ttattaaata agataaaaaa taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 tacttttgag ttagaaaaaa ctctatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 gtgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaactcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gctataataa
    10021 ggtgataaat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaatagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttgaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaagatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggatgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaaa
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt tgccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggaaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca ttcatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccagttag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcagggaca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aggttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gatgatatta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagtga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttcg gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcagttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagc atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tggtttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tattgctgtt aaacaaggag
    14821 atatggttaa acagggagat gttcttgtta atgttgattt aaagagaata catgaattag
    14881 gaaagtctac tttaacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatgaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAMJWC010000206        12105 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.guided.098, whole genome shotgun sequence.
ACCESSION   DAMJWC010000206 DAMJWC010000000
VERSION     DAMJWC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12105
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.guided.098"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            158..1564
                     /locus_tag="PC503_003782"
     CDS             158..1564
                     /locus_tag="PC503_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2529682.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            1592..2440
                     /locus_tag="PC503_003783"
     CDS             1592..2440
                     /locus_tag="PC503_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2529683.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            3101..3793
                     /locus_tag="PC503_003784"
     CDS             3101..3793
                     /locus_tag="PC503_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2529684.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            3790..4725
                     /locus_tag="PC503_003785"
     CDS             3790..4725
                     /locus_tag="PC503_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2529685.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            4873..5796
                     /locus_tag="PC503_003786"
     CDS             4873..5796
                     /locus_tag="PC503_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2529686.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            5780..6550
                     /locus_tag="PC503_003787"
     CDS             5780..6550
                     /locus_tag="PC503_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529687.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            6560..7342
                     /locus_tag="PC503_003788"
     CDS             6560..7342
                     /locus_tag="PC503_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2529688.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            7719..8255
                     /locus_tag="PC503_003789"
     CDS             7719..8255
                     /locus_tag="PC503_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2529689.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            8287..8676
                     /locus_tag="PC503_003790"
     CDS             8287..8676
                     /locus_tag="PC503_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2529690.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            8713..9099
                     /locus_tag="PC503_003791"
     CDS             8713..9099
                     /locus_tag="PC503_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2529691.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            9226..10668
                     /locus_tag="PC503_003792"
     CDS             9226..10668
                     /locus_tag="PC503_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2529692.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            10965..11780
                     /locus_tag="PC503_003793"
     CDS             10965..11780
                     /locus_tag="PC503_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2529693.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         4362 a         1495 c         2280 g         3968 t
ORIGIN      
        1 aatatagagt aagtttattg taatgaattg ttaaagaaaa taattaatat agggtaaatc
       61 tatctcaatg aaataacaaa gaaaagagtt aatatagagt gaacttattg caatgaatca
      121 acaaagaaaa taatcaatat aaaaaggaga aatatttatg aatacaggat ttccaaaaga
      181 ctttttatgg ggagcatcat cttctgcatt tcaagtggaa ggagcttggg ataaagacaa
      241 taaaggaaaa accgtagccg actataattc ttttaaaaag tctcatttac aggcagatac
      301 taaagtcgca tcagactttt accataatta tgaagaagat attgaattaa tgaaagaatt
      361 agggatgaaa acatatcgtt tttcaatttc atgggcaaga ataataccag atggtgaagg
      421 agagataaac cagaaaggtt tagaatttta taataagata atagacaaac tgatagagtg
      481 tgatattgag ccattcgtaa ctttatacca ttttgacctt ccatttaaat tagtagagaa
      541 atataatggt tgggaaagta gagaaactgt ctatgctttt gaaagatttg ctaaaatatg
      601 ctttaagcat tttggagata gggtaaagta ttggcaacct cataatgaac agaatttaat
      661 tgttagagtg gaggagagaa ttaatatata tgatgaaaca gattcatgga agatagataa
      721 aatgcgtgct cagatggatt ataatctttg cttagcacat gcattagcag tcaatgcatg
      781 tcatgagatg ataaaagaaa gtaaaattgg agcagcagta tcatcatctg taacatatcc
      841 tcttacttct aagccagaag atgtatatgc agctagaatg aatgataatt ttaaagtgta
      901 ctatatgctt gatatgcatc attatggaga atatccaggg tattatatga agtatcttga
      961 aaaaagaaat atagttcctc acatggaaga tggggataaa gagatactta aaaaagctaa
     1021 aatggatttt atagctgtaa attattatag gacaaattgt gcagaagctt tacctgaaga
     1081 ttcacaacat ccatttggat taagagaagg aactgttgat tttagtatgt atggactatt
     1141 taaaatgtca atgaatccta acttagaggc ttctgagtat ggagcagcaa tagacccatc
     1201 aggtcttaga gttgccttaa atgaatattg gcaaagatat cacttacctg ttataataac
     1261 agaaaatggt ctaggagcta aagatatatt agaagatgga aaaattcatg atgactatcg
     1321 tatagactat ttaagaagtc atataaatgc atgtaaacta gctattgaag atggtgtaga
     1381 gatgattgga tattgtccat ggtcatttac agacctttta agttcttctc aaggttttaa
     1441 taagcgttat ggacttgttt atataaatag aactgaccat gaagttttag atttaaaaag
     1501 aatcaagaaa gatagttttt actggtataa agaagttata gagaacaatg gaatagtaaa
     1561 ataaacataa atatatattg agggttttag tatgtacatt acaaaggtat taaataattc
     1621 gttgctactt gcaaaggatg ataatgatga agaaataata ttgatgggga aaggcattgg
     1681 ccataattat aaggccgggt ctgagttaaa taaaaaagat atagaaaaga tttttgttct
     1741 tcatgatgaa aatataaaaa agagtattat acaattggca acagaaatag atgcagaata
     1801 ttttggtata gctcaaatga taattgcata tggaatagaa aaatataact taaaacttat
     1861 gaaccatata tatttggcct taactgacca cattgccttt gcagtgagac gttttaaaga
     1921 aggtataatg attgaaaatc actatttgtt cgaaatcaag gaatttaatc caaaagagta
     1981 tgatatagga aaatatgcta ttactgtttt taaggaggtt cttggtttag acctaccaga
     2041 agaagagatt ggtaatatag caggccattt tataaatgca caacaagata atccttatag
     2101 tgatagaaat aagagaagtg ctaaaattgt aaatgctatt ttgcaaatag ttcattatca
     2161 cttttctatt gtatataata aagagtcatt ttattatagg agatttgtaa tgcatctaaa
     2221 ggccttttca caaagatttc tggctaatga accatcaaga gaaaaaatag attttatata
     2281 tgagcaagtt caaaaaaatt gtaaggaaga gtatgaatgt gtgaaaaagg taggagctta
     2341 tatgtataag gaatactcca gagaattacc aagacaagag gagttatatt tgatgattca
     2401 tattcataag attttaggag aattatgcga aaatagttag aatatcttaa tatgctagta
     2461 atattataaa aaattaaaaa ttaactgcac tttaaatatg aataattgca ttacttaagg
     2521 gggttgtctt aaaattgatt tttttaatta aatttgaagc tcaactcctt ttttaaacct
     2581 ttatatcatt acaactttaa tgtttatacg actgtacttt agatgtatat ctacttttta
     2641 catttctcaa catgcaaacc taccattttt tgcagtatgt taattgaaat aaaccattga
     2701 gttaacccta aatttattct ggacttatag gaatagttcc aaagatactt taaaatattt
     2761 tctggaataa ttgcttattt cacatatgtt ttattgtgat gttttgattt aataaattct
     2821 tcaactctgt atatagtaaa tgtattatca tgtttgtttt attcaagcac acttataata
     2881 cgcttgattt tttcacaatg atgaaatata ctaatgggtg ttataggtat aagaatcgca
     2941 ttacacttga agaagtaagt gataaatgag gtataaatcc tcatatgata aactactatt
     3001 tcattgagga acatattcta agtgatgtca agatactaca atatgactaa attcctagtg
     3061 ataaaaaagt ctacgaatga gtgtagaaag gggaactaag atgaataaag ttttaattat
     3121 agatgatgat aaagatcttt gtattttgtt aaaaaagagt atttcaattg aacagattga
     3181 agcaaactat tgccattctg ggagagatgg actggttgaa ctttcaaaac aagattatca
     3241 gttagtagtt ctagatgtga tgatgccagg tatggatggt tttgaaacta tggaacaaat
     3301 acgaaaatat agcagtattc ccatcttaat gctgacatca aaaagcgata attacagcaa
     3361 agtgcatgga ttgcgagctg gtgcagatga ctatctaacc aaaccatttg aaattacaga
     3421 atttactgct cgtgtactgt ctttaatccg acgttacacc cgttttaatc caaaaaatga
     3481 ggagccacag caactttctt tcaaaggttt gttgattgac cttgaccagc atacagttac
     3541 taccaatggc gaacctatgt tgcttccacc caaggaattt ggtgtacttc tttactgtgc
     3601 aaggcatcag ggtaagattt tgacaaaaca gcagatttat gaagccgtgt ggggtgagcc
     3661 atatgtatat gatgacagca atatcatggc tattatcagt cgcctaagaa aaaaaattga
     3721 actagaccca tcatctccca tctatttgca aacaataaaa ggaattgggt atcaattcaa
     3781 cacggaggta tgaaaatgga tgaacaaacg ataattcttt tcttactctt gctgtcgatt
     3841 ggtctacttt ttctttccat atttgctttt tccaagcttg ggcatattta caagcgccta
     3901 aaagatatag aggagatact ggctgatgta caaattggag acgaaaatcg taaaatacta
     3961 attaagccat gtgatgttat ggctccattg gtttatcagc ttaatgagat tgtctacgat
     4021 tatgaaaata agttactttc tctgaaaaag tcggataaag ctagcaaaca acttatgaca
     4081 agtttatctc atgatgttcg tacaccatta acaactctga ttggttatct ggatgctgta
     4141 cacagtggta tagttatcga acaagagcgg gaggaatacc ttgaaatcgc taggcgtaga
     4201 gcctacgacc tcaaggatta cattgatgtt ctttttgact ggtttcggtt gaactctgat
     4261 gaatttacgc tgtcaataga atctgtggaa attgcagagt tgtcacgcaa tattttgaaa
     4321 gactggattc ctatattcca tgaaaagaaa ctgaattttg aaattgatat tccagaaaat
     4381 cgactaatgg taaacctcga cccagatgga tattcccgtg tggtcaataa tctggttcaa
     4441 aatgttcttg ctcacagtaa ggctcggcaa atcaagatta ccatgagtga ggattccaga
     4501 atggtattac tccgtgttga ggatgatggt gttgggattg ccagagaaaa tttaccacat
     4561 atttttgagc gactgtataa gtgtgataaa ggacgttcag aaaaaggaag tggtcttggt
     4621 ctatctattg tcagtcaaat ggtggagcga atgggtggtc aggtttccgt agaaagtgag
     4681 attggaaagt ataccgtatt tacagtgagc ttaccattaa tataaaattg tttttccccc
     4741 atgtgacatg tatacacatg gggatttttt gtaagttata aagttgcaag gttaatacaa
     4801 ggttgttgca aggttaatgt aagattgagg tggtatgata actttaataa acaaaggagg
     4861 cttttattat ttatgaataa tttaattatt gaaacaaaaa atctcactaa gcaatatggt
     4921 gctcaaaaga gcgtttctaa tttgaatatt cacgttcaga aaggtcgcat ttacggattg
     4981 ctaggaagaa acggtgcggg taagacgaca actatgaaaa tgttattggg tctaacaaaa
     5041 ccaactactg gagaaattaa aatatttggt caggacattc acaataacga gaagaagctt
     5101 cttcctcgaa ttggatgttt gattgaatca ccagggtttt atcctaatct gacaggaaca
     5161 gaaaatctca aaatctttgc aaggcttaga ggaataccaa aaaaaaatgc agtagaatca
     5221 gcactggatg tagtcggttt gccaaacaat gacaaaaagt tattttctca atactctctt
     5281 ggtatgaaac agaggttggc gattgctctt gccattatgc atgacccaca actgttgatt
     5341 ttggacgagc ctatcaatgg acttgatcct attggtattg cagaagtaag aacgtttatt
     5401 cgtgatctct gcacagaacg aggtaaaact attttgattt ccagtcacat tctttctgaa
     5461 attgccttgt tggcagatga cattggcatt attgaccatg gtattttgtt ggaggaagaa
     5521 agtcttgccc aattagaaga aaaaaacagt aaatacatac attttgctgt atctgatgca
     5581 gcacaggcag caaggcttct ggaaacccaa cttaacctga aaaatttcaa agtagcagat
     5641 aattacaata ttatgctata tgatacagat gtttctgttg cagaaataaa tcgtgctttc
     5701 attctaaaca acattgaggt atcagaatct catttatgcg aagatactct tgaagattac
     5761 ttcaagaaag taacaggggg tgaaggaatt gcttgatata atttcatgtg aattttcaaa
     5821 actcaagcgg ttaaaattta tactgatttc tattttaggt gcttgcttat ttccaattcc
     5881 cgcaacaatt ttgattgcaa aggacaactt gccctttgag caattgttca aattagttgt
     5941 caattttgga tattttttgc tattaccaat tgtattaagt attgttgcta gccaactatt
     6001 ttttatagaa agagataatg atgtattaaa aaatcttgca acagtgccag tgcaaaaagg
     6061 aaaactggct ctggcaaaat tggctgtgtt gctgtttata tcattgttct actctgttgc
     6121 agggttagga gctactatca ttggaggttt cattgttgga atagtagagg gggttgctgt
     6181 aaaattagga atgagcattg cttttggaat tatgtttttt gttactgtac ttcctgttgt
     6241 ggtactcatt gtatatttca atcgcagcta tattttttct attatacttt cttttgtata
     6301 tgctattttc aattttagta tatccttaaa tattatcaat tttgaaccaa ataacccaat
     6361 attaagtgta ttacctgctc ctgttataat gcgttggtgg atggcatttt ggggagatcc
     6421 cactggcgaa tacacggcac ttagacagcc atatttgctc tcaactcctg cttgtgtagg
     6481 tattttatgt ttgataacca ttatagcagt cctgctgatt tgtatgatat acaaaaagca
     6541 ggagaattag gaggtatcta tgcttgatat aattactaca gaatttcaaa aaataaaaag
     6601 atataatatt ctatggattg gtgttgttgc tgttctgttt tcagcactat tggcagtttt
     6661 tcaggttgta agttcacacg gcagtgaccc tctaacgtat gagagctttg caaacggagt
     6721 tatctggaat aatttcagtc ttagttttcc atttgggatt acacttattg gaggatatct
     6781 tattaaccgt gaatatacag accaaacctt aaaaaacatc ctaactgttc ctatttcatt
     6841 acgcaaattg ctagtgggaa aattaattgc ggttggagga attactgtat tgttaagtct
     6901 tttcagcttc ttatgcacat ttattttggg gttgttgttt tgcaatatca atatatctgt
     6961 tacactcgtt gtaaaatcct tagttcagat tttgtctgtt aatctgtatt gttatgttgc
     7021 tgttttgccg attattgctt attttggtcg taaacaaaat gcatttctga cgggtgtagg
     7081 gattgcattt gtatacggtt tttgtggtgt gtttgttgct ggaagaaatc tgacagactt
     7141 ttatccaatc acagcaggtc ttggtctagt tggatacaac aatggtgctg gtactgttta
     7201 tcagccactt atcggtgcta tgactttgat tgtaattcta atcttgacaa ctattctact
     7261 tgtatttaca cctaattatg ataaagttat gaccatatct aagaaaaaag ggataaagca
     7321 taaaaagtat tctcataaat aacataaata ttgtttctat tatttaagtt gctagacagt
     7381 gaaaagaaaa aatctgtcgt acagtgtcta tatgctcatg tattcaagaa gctacagttt
     7441 tgatttttca taactgtagc ttctttttgt atttattaaa tcacgactat cataatactt
     7501 gcaataggta tagcgacaag agagagtact gtcatatgtg ttttatatat tacattaagt
     7561 atattctaaa atatatgttt taaataatat atttgaaaat aggaatattt aaataaaaaa
     7621 aataatatta tatatagttg acaaaaattg gcaaatgaga taatatataa atatagaaat
     7681 agtaatcatt actattatta aaaagggagg aattaattat gaacttaaaa ggaactaaaa
     7741 cagaaaagaa tttaatggca ggatttgcag gagagtcaga agcaagaaat aaatatacat
     7801 actacgcttc aaaagcaaga aaagaaggtt ataatcaaat agctgctata tttgaagaaa
     7861 ctgctaacaa tgaaaaggaa catgctaaat tatggtttaa acttttacat gatggtatgc
     7921 cttcaacaga ggaaaattta aaggatgcag cagcaggtga aaactatgaa tggactgata
     7981 tgtatgcaaa atttgctaaa gaagctagag aagaaggatt tgacaagata gcttatttat
     8041 ttgaagctgt tggaaaaata gagaaagagc atgaagaaag atacttaaag cttttagaaa
     8101 acttaaatga aggaaaaata tttaaaagag atgaagaagt tgtttggcaa tgtcaaaact
     8161 gtggtcatgt gtatgtaggt actgaagcac cagaaaaatg cccagtatgt gaccatccaa
     8221 aagcgtattt caatataaaa gctgaaaatt attaaaaatt atcattatta aaaaggaatg
     8281 ttaactatga aattttctaa acaacgagaa ctgattttaa atgaaatatt aaataatccg
     8341 gttcatccta ctgcggatta cctatatgaa aacttaaaaa aagataatcc aaatttaagc
     8401 ttaggaactg tgtatagaaa tttagctcag ctaacggaac atggctttat aagaaaggtt
     8461 agtattccag ggtatccaga tagatttgat ggtcgaatag ataatcacta tcatatcata
     8521 tgtgaagtat gtggagaggt atacgattta gaatccgaag ttcttaataa tttacaagaa
     8581 ttaatatctg aggagacaga cataaaaata acatcttata acataagttt taaagggatt
     8641 tgtaataatt gtaaaaggtg tagccaagta ggttagtttt caaattctaa aaataattaa
     8701 tgaggtgagt ttatgtgtag tgaacaaaaa ttttttatat gtgagacttg tggaaacctt
     8761 gtaggaatga tacaaagtgg tggtgtacct attttctgtt gtggaaaacc tatgaaggaa
     8821 cttgttccta atacaacaga tgcagcagtt gaaaaacatg tacctgtaat tgaagtggat
     8881 ggaaataatg ttactgttaa agtaagtagc acaactcatc caatgactaa agaacatcat
     8941 atagcatggg tgtatcttat gactgaacaa ggtggtcaac gcaaatgtct agcagtagat
     9001 ggagaacctg tagttaaatt tgctttgaat gatgatgata aagtgatttc tgcctatgct
     9061 tactgtaatt tacatggatt atggaaggct gaactgtaat atttaaataa attgagtcaa
     9121 aaaggaggct ataaatgtat tttcatacaa atagcctcct ataaatttat ataaattcaa
     9181 gttttaattt tgtttaatgt caatataata taaggagaaa ataatatgtc aatttataaa
     9241 tgtagtgttt gtggatatat ttatgatgaa tctaagaatg ataaaacatg ggatgaatta
     9301 agtgaagatt gggaatgccc tgtatgtaca aaaggtcgta gttattttgg aaagataagt
     9361 actgtttact atgaagaaga tgaaaagata gcagaagaca tagttgaaga tgaatctaaa
     9421 ttaaatactg aaaaagaggg agatttaaat tacttaagta catatttaag aagagatgat
     9481 gaagttgaga aacatatgga tataattcac gaaatggctg ttacaggaaa atctataata
     9541 gaacctatga gaactaaact accagtaatt tcttgggatg atattttaat tatgggtgct
     9601 caattaaatc cattaccttt aaatgagcat gatgaagtaa atacaacaac aataatagga
     9661 aaaaaagcaa agaaacctat gattatagaa aatccagttt atatttccca catgtcattt
     9721 ggagctttgt ctaaagaact aaaaatagct ttagcaaagg gtgcagccca aaataagaca
     9781 gctatgtgta gtggtgaagg aggtatatta ccagaagaga aggaagcttc atacaagtat
     9841 atttttgagt atgtaccaaa taaatatagt gtaactgaag aaaatcttaa aaattctgat
     9901 gctatagaga taaaaattgg tcaaggaaca aaacctggta tgggaggtca tcttcctggc
     9961 gaaaaagtaa ctgaagaaat agcaaaagta agaaataagc ctgtaggtca agatgtaata
    10021 agtccatctt gttttgagga aatacaatcc aaagaagatt taaagaaact tgtagatgaa
    10081 cttagagaag tttcagaagg gcgtccaata ggtgttaaaa tttcagcagg tcatattgaa
    10141 aaagatatgg aatttatagc ttatgctaaa cctgattttg taactattga tggtcgtggt
    10201 ggagctactg gagcaagtcc aaagttgctt aaagatgcaa cttcaattcc aacaatattt
    10261 gctctttatc gtgctagaaa atacatagat acacatggat tagatataga tttggttata
    10321 acaggtgggc ttcgtatatc tactgatttt gctaaggcaa ttgctatggg tgctgatgca
    10381 gttgctattg caagttctgc tcttatggca gcggcgtgtc aacaatatcg tatatgtggt
    10441 tctggtaagt gtcctgtagg agtagctact caggatgagg aattgagaaa aagattacat
    10501 atagaaaaca gtgctaatag agtggcaaac tttttaaatg taagtttaga agaacttaag
    10561 acttttgcta gaatttctgg tcataaagat atacatgatt taagtgttga tgatttatat
    10621 actgttaact ctgaaatatc aaattataca aacatacagc atgtatagat tgaagtttga
    10681 aactattaga ttttagatag ctataaaagt aaatgataaa tatattttat aaaagagagt
    10741 gtcttaaaat gaacttttta gttcataagt cactcttttt tttatgaagc caaatatatt
    10801 tatcatttta gcaatgaaaa agaatcttat ctctttattt tgagatagac tccttctatt
    10861 tatgaaaatt aaagatatta aattgtaaaa tattctgtga tgtcgtacta ttaaactaaa
    10921 gattctgtac tttaaagtaa ataaaaattt aaggagtgat tattatggaa agattgaaga
    10981 tacaagtttt agttgacaat aatacttata ttgatagata ctttgttgga gaaccagcag
    11041 taagctatta tattgagatt gatggaaata ggattttgtt tgactcaggg tattcagatg
    11101 tattcatatc aaacgctgaa aaattaaata tagatttagg aaatttaact catgttgttt
    11161 tttctcatgg gcataatgac catacaagag gtatccagtt tctagaaaat aggtatgatt
    11221 tatctacagt tgaacttatt tcacatccta actgttttat acctagaaaa catggagaga
    11281 aaagcatagg agctccattt tctgctgagg aaattaaaaa tatttttatg tataatccta
    11341 aggataagcc atttaatcta agtaagaatt gtgtgttttt aggtgaaata ccttctataa
    11401 atgattttga aaaaagagct aaaattggta aatgtaaaat aggagatttg tgggaagatg
    11461 attatgtttt agatgattct gctatagttt gtaaaactga taaaggtatt tttattgtta
    11521 caggatgttc tcatagtgga atttgtaata tagtagagta tgctaaaaag gtatgtggag
    11581 atgatagagt tattggtata ctaggtggtt ttcatctttt tgaattgaat aataggttag
    11641 atagtacaat acaatatttg gataaagaag aaatgagaat gttgtaccct tgtcactgtg
    11701 tttcttttaa ggtaaaagcg aagatgaatg aaatattgaa tataaatgaa gttggagtag
    11761 ggctgaccat aagtatatag tatttgaaag tatataagat ttaagttgaa ggttaaaaag
    11821 atattttcta tagaaaatat cttttttgtt acgtttattt taagagaaat caatatactt
    11881 ttatatgaaa tattgtaaaa aaatttattt ttaatgagaa tatattttca ttaataaaca
    11941 attttattat gtattaataa tgttagaata aatataaata aatcaaagtt acttacatta
    12001 cagtatattt tttcacaaaa tatattgatt tattctttta aagtttgata attccaatga
    12061 atgtaataaa agaaggaatt ttatactata cgattattat tatat
//
LOCUS       DAMJWC010000207        11144 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49307 isolate JH308
            SAMN32366151-rid16589913.guided.104, whole genome shotgun sequence.
ACCESSION   DAMJWC010000207 DAMJWC010000000
VERSION     DAMJWC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366151
            Sequence Read Archive: SRR22863008
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560864.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560864.1
            Genome Coverage       :: 254x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 01:43:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,808
            CDSs (total)                      :: 3,720
            Genes (coding)                    :: 3,678
            CDSs (with protein)               :: 3,678
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 3, 4 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 42
            CDSs (without protein)            :: 42
            Pseudo Genes (ambiguous residues) :: 0 of 42
            Pseudo Genes (frameshifted)       :: 14 of 42
            Pseudo Genes (incomplete)         :: 19 of 42
            Pseudo Genes (internal stop)      :: 18 of 42
            Pseudo Genes (multiple problems)  :: 8 of 42
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11144
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366151-rid16589913.guided.104"
                     /strain="NR-49307"
                     /isolate="JH308"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            273..611
                     /locus_tag="PC503_003794"
     CDS             273..611
                     /locus_tag="PC503_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529694.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            633..950
                     /locus_tag="PC503_003795"
     CDS             633..950
                     /locus_tag="PC503_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2529695.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1100..1777
                     /locus_tag="PC503_003796"
     CDS             1100..1777
                     /locus_tag="PC503_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529696.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2105..2872)
                     /locus_tag="PC503_003797"
     CDS             complement(2105..2872)
                     /locus_tag="PC503_003797"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2529697.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3544..4359)
                     /locus_tag="PC503_003798"
                     /pseudo
     CDS             complement(3544..4359)
                     /locus_tag="PC503_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            4460..5158
                     /locus_tag="PC503_003799"
     CDS             4460..5158
                     /locus_tag="PC503_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2529698.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            5246..5866
                     /locus_tag="PC503_003800"
     CDS             5246..5866
                     /locus_tag="PC503_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2529699.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6022..6804
                     /locus_tag="PC503_003801"
     CDS             6022..6804
                     /locus_tag="PC503_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDF2529700.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6929..7855
                     /locus_tag="PC503_003802"
     CDS             6929..7855
                     /locus_tag="PC503_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2529701.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            7869..8318
                     /locus_tag="PC503_003803"
                     /pseudo
     CDS             7869..8318
                     /locus_tag="PC503_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8678..9085
                     /locus_tag="PC503_003804"
     CDS             8678..9085
                     /locus_tag="PC503_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2529702.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            9087..9317
                     /locus_tag="PC503_003805"
     CDS             9087..9317
                     /locus_tag="PC503_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2529703.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9707..9910
                     /locus_tag="PC503_003806"
     CDS             9707..9910
                     /locus_tag="PC503_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDF2529704.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            9988..10341
                     /locus_tag="PC503_003807"
     CDS             9988..10341
                     /locus_tag="PC503_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HDF2529705.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10413..11045
                     /locus_tag="PC503_003808"
     CDS             10413..11045
                     /locus_tag="PC503_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2529706.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         4108 a         1575 c         1747 g         3714 t
ORIGIN      
        1 tctaatatgt aattacaata aaaaatgcta taattaacat attattaatt cgttttatta
       61 ttgtagtatg gctatgaaat tatgaaaata tttctctaat taaaaatatg atttatccat
      121 atttgtttat tgtagataca gactatacaa aaataaatag cacttatttc agtataaaaa
      181 catatatagt ctatatttag actaaaaaag tataaatagt ctatataaaa caacttaaac
      241 tatgaatata atctaaagtg gagggataat aattggcaaa tataggaaaa ataataggag
      301 atagaataaa agtctataga acaaaattgg gatatagtca agagtttcta gcagaaaagg
      361 caggtttaca tccaacatat attggtcaga ttgaaagagc tgagacaaat acatctatca
      421 atattataat gaaaattgct actgctttag acataccact tgaattgtta tttgcaaata
      481 ttattacaac agaaggcgtt gataactctg tacctttaga atgttatgaa atgattaata
      541 aattaactga aaaagaacaa attgcaatgc tagagttaat aaagtgcatc attaaataca
      601 aagaaatata agtgagggaa atagtaacaa taatgaatta tataggtaaa agacttaaag
      661 aagaacggaa aaaagcaaat ttaacttcaa aagaatttgc aaatatggtt ggagtatcgc
      721 cttggtatat aactcaaatc gaaagtggta aaaagaatcc aagtcttaaa acattcataa
      781 aatttgtaaa tatattaaat atttctgcag atgttcttat aaaagatatt acttccactg
      841 gaaaaacata tttagaaaat gatataaatg aagagttaaa agacttaaat tcaagagaac
      901 taaatctgat atcacagatt atagacatca taaaaaagaa taaaatataa ttctttatat
      961 tttatataaa aaaaaaggtt atttgaaata aataaccttt ttttgtcttt ttgtgttaac
     1021 attgtcttat agtgctaatg agtactatta gaccatgttc tatggcctta ttttaatata
     1081 aaacgattgg agataggcta tgattgtgat tgaaggtagc gataaattta agattgcaaa
     1141 agaatatatt gatgtagaat atactctttt tagcaaagta acttttaggt atgaaaagtt
     1201 gaaatttaaa gataatgctg aattggaaaa aattaagatg tttaaatata aaaatggcta
     1261 catccctaat aaattaaacc tttcttttgg atatggattc tcttcttata aaaagcaaat
     1321 aattagagaa actgtagata ctttaagatt gacagaaatt ttttcaagcg agaacataga
     1381 agatattaaa tttataaaag atggtacaaa aaaattagaa attagcatag agaaagttgt
     1441 gaaatttaaa cgtcgaaaaa aaagaaatta tgtttgttgc tattgccctg atatgtatag
     1501 agacataaaa ctcgacaaag aatctatcaa taagatatac aacagaaaaa taaaaataga
     1561 aagagaagtt aatatttttg aagatgagga tgttataata aacaagaaag tattgaagtt
     1621 tccaaagtct tggacaaaga atatgcaaaa atattggtta agtgaaaata agtatcccat
     1681 acattctact gtaattgatg atgatagata taaatgttgt aatgtacaat atacaaaaaa
     1741 tagagtgata atattatatt acatatataa ccattaatat acataattac aaaaaaataa
     1801 tgacaaatat acataataca aatatatctt ctactttaga taaaacagtt attatgaaaa
     1861 cttactatct ataaataata gaaatgctag tataccatct ataatctaat gtctagtagg
     1921 ttttaatggc atattttaaa tatgccatag ttgatttata agattttcta tatcactttc
     1981 aaaatacaca ctaaatagtt gcttttcaga tataattgcc caatttaaat tttactatct
     2041 gaaaagtttt ttatatttaa tttatatctt caaaaatacc gtctaatatt tctatataat
     2101 taatttaatt aatactctta tgtaatagat taagtactga atttaactct ttaaatgata
     2161 tttgccctgg tgctgaaaca ctttttgcag ctccaaaagt caatgcagaa ccaaatattt
     2221 caccacacaa tctacttata acacccattc ctgacattga cattgttatt attggtctat
     2281 ctgcataaat tttaaacatt tcatttgtag cttcaagtag cactaacaca tctttttcat
     2341 tttgcggcat aacagctatt ttgggtaaat ctgcgcccaa ttcctgcatt ctacataaac
     2401 gagatacaat ctcttctttt tttggagttt tattaaaatc atgattagat ataattactt
     2461 tcacttcttt tttatgagca aaattaacta cttcatctat gacctcatct cccataaata
     2521 actctacatc tattaaatct actaaacctg tattagaaat ttctttattc aaagtagtat
     2581 aataatctct tgatattaat ttttctcccc cttctactac acttctaaat gtgaataata
     2641 aagggatatc atgtatataa cttcttaatt catagagaac ttccttaact tctttaatat
     2701 tttctacatt ctcaaaaaaa tcaactcgcc actctataat atccaaacat gcatctttta
     2761 actctttagc ctcttttata atatcttttt tatttttccc aataattggt acacaaattt
     2821 taggtctacc ttctccaata gtaatatttt ttacttgaac ttttcttttc atattctcct
     2881 ccataatcag aaattctata ggactttaaa ttctattttc tgcacaattt aattatacat
     2941 taaaaatact atacattata aaaatactaa tttaaaaata atttttattc taattcttaa
     3001 aacaatccca catattttag aaaaggtact ctataatata caaacacttc ttttttacct
     3061 aaatttattt taacatccta taattttcac aatattcttt aaattttact catataaaca
     3121 atattattct ggatgctaat agaattaatc tataaatcat agtataatta tgcagaaata
     3181 actcgaattt cactacttat gaagagattg aatattaatg aatctaaatc atttgcatta
     3241 cttaagagtt ttgactaaag ttgaacacca tacaaaagta gctactcaat tgtttatacc
     3301 ccaaccaagc ttaagtaatg ttatatagat tctcgaaaaa gaatttggta tctttttatt
     3361 tgaaaaactt atattaaatt tgattatctt ttcataagtt ggtaaatgtc gatatatcct
     3421 gtatctacaa ggagtatcgg cattttcttt ttggaagata ctttgcataa gttggcattt
     3481 aaccgtataa gaatgccatc aaaagtagta aataagtagt aaactctagt catactacta
     3541 ggattataac cgttccattt cagctctcga agaactaaat gaaccatgtg cataatagcc
     3601 aagcgtcata gtaatgtttt tatgccccat aatatattgc aatatattag gactcattcc
     3661 tttgttagcc atatttgtac agagtgtatg cctaaaggta tgtggcgtaa tctttggtag
     3721 cttgtcctca tgggtcttat tatacttctt gactaacgct cttaacatgc tttgataatg
     3781 agttgcttgt tttggtaatc catcttgttt aagaaatagg aagttctggt aaccatcaac
     3841 aatgattggt tctgctttag cgttcttacg ccgttccacg atacgttcaa atgattgata
     3901 agctctttca gtcattggaa tttctcgctt accctgtgtg gtctttggaa cttctacata
     3961 atagccaatc ttagtatcac tcaacaattg atggtctacc ataatggctt tatttttcat
     4021 atccaattct aaagtcaaac cgcataattc agaaatgcgt agtcctgttt ctaagaggat
     4081 aacaacatca tcataatatt tacaataagt cttatcgctc cccataaagg ataataagcc
     4141 catttcctgt tctggtgtta gagcgatttt tggttctgtt gtatcttcca aaacatcact
     4201 taactaaaaa ttaaatggat tctttctaat acagtcgtct tgaattgcca tgaaaaacga
     4261 cgctttcagt gagcgcttat aattgtcaat ggatttataa gcacacccat cttcactcat
     4321 tcggatagcc cagcttttag cgtctgataa tttaaccata tcaatgcttt ttgcacctag
     4381 tgggtcattg atagtatcta tattttgatt tataatttat acattttttt aaaaacagac
     4441 ttttaactgt aaagaatcta tgtataaact tagctatgtt gtccgtgtat ctacaaagaa
     4501 tcttgacgag ctaaaaaggc gttgtgatga agtcaaagac ttttacgacg acttatcaat
     4561 caagctcgtg cgtccctttg gggatatgtt gggattgcat ggcgaattta ttcctgtcag
     4621 caaacgttac atcaatgatt atattcaata tgtcacttcg gattttttgg ctggacttgg
     4681 ttttggagcg acacaaaccc ttggcgaaca tgaggatatc tatcttggct acaatctgga
     4741 cactggaaag aatgtctatc taaaacctgc ccttgctagt caaggggtaa agggttctat
     4801 taccaatgcg ttagcgtctg cgtttatcgg ttcattgggt ggtggtaaat tattcagtaa
     4861 caatatgctt gtttactatg cggtactatt cggcggacag gcggtcatag ttgaccctaa
     4921 agcagaacgc ggcaaatgga aagaaacgct accagaaata gcccatgaga taaacattgt
     4981 caatttaacc agtaatgatg aaaacaaagg attgcttgac ccttacgtca ttttgagccg
     5041 taaaaaggat tctgaaagtt tagcgattga tatcctaaca ttccttactg gtatctccag
     5101 tcgtgacagt gataagtttt tgcagaaaaa tgacaactgg aaaataataa tggaatagtt
     5161 tctatgtaaa tatattttta ctatcttacc taactaattg aaagatgata taatttaatc
     5221 aaagatttgg taaggaggga tgaatatgca tttaattgat tttatgaatg aagatattaa
     5281 aaagaagctt gttaaaaaaa cgtataaaaa gaaagagact attctttttg ctgagcaaga
     5341 aaatgaatat gtaattctta tgattgacgg tattgcagaa gcattcatct taaatgtgaa
     5401 aggaaacatc tcaacgattc atctttatag aagtggtagt ttttttggag aaatggaaca
     5461 atttaatgat gggaaaaaac ccgttgaaat tgtcgctttc acagattgta atgtatataa
     5521 acttcataga gatgattttt taaactggtt aaggggagat tttgaagcta caaaatttct
     5581 gattcgagaa atatctagta aattagttgt aaatgctgaa ttaattgaag aattatcatc
     5641 tttaagtgtt aaagaacgac ttctgaggtg tatatcctta cactattata gaagtgaatt
     5701 aaatctgctt accaaaaaac agcttgctag cgaagtaaac gctccaatta gaagcattaa
     5761 tcgtgctata aatgaatgtg tacaagaaca tctaattgct tatgaaaaca aaagatttag
     5821 tgtaattaat cagcgagagg tattaaagaa tcttcctaca acataagtat aatttcaaaa
     5881 aagtattgaa taataattat tcaatgcttt tttatttcgg gtcaagtgac ctattttttt
     5941 ttatttcttc attatataat actcctatgc ataattatgt tggattgata gctaataaaa
     6001 gacagtgaga ggtgttatat tatgactaaa acacaacaga aaatgataca aaacgtatta
     6061 gaattttcaa aaagagatag taggataata ggacttgcaa ttagcagttc ttatatcaca
     6121 aaatcgttag atgaatattc tgatttggat tttctgattg tagcagatga taaatcctat
     6181 gaagaagtta tcgaagagag attacttatt gtggaacagt ttggaacatt agtttctgct
     6241 tttactggcg aacacgttgg agaacctcga ttgataattt ccctctatga ttcccctgtt
     6301 cttcatgttg attttaagtt tacaacctta gatggtttac tagatagggt tgaagattca
     6361 gctattctct atgaagaaaa caactgcata acagaaattt attctaaaaa agaagcatac
     6421 ttcccaactc cagacttaca gtggattgaa gatagatttt ggatttgggt tcattacgct
     6481 tgcactaaga ttggacgtag agaactattt gaaacaattg attttttatc ttttttaaga
     6541 caatcagtac ttgccccatt aatacagctt ctcttaggta aattacctcg tggagttaga
     6601 aaaattgaat tggacgcacc ccaatatatt gaagcattag aaaagacggt tgctaaccat
     6661 gaatataaaa gctgtgttaa tgcattgcag gctactatca acctgtatct tgagttaaga
     6721 gaggaattat cacaaagtcc tattgtccga aaggttgaag ctgaaagggt tgcattacag
     6781 tattttcaag atttaatcaa ataaacccaa agtaaaaaaa tattgaatag taaatattca
     6841 gtgttttttc atttttggtc aaatgaccta gattagttgt tgtaacaatt ctataattat
     6901 tttgaaagta acagtatgga ggataactat gagtgatatt ttaagtagaa ttacaaataa
     6961 aattggggat aagaatatag ttgataagtt atcagctcta tcaaaatcag atttgaactc
     7021 acttctatta gaagtgtttg atagacaagc aaatacttta actgcaactg atattctaaa
     7081 gtcataccaa ctaaatagat ttactatccc tagcggtata gatccagaag aaattcatgc
     7141 tttggaatca aaattattga gaaaagcatt caatatggat atcaagacga ttatgctttc
     7201 tccctctgcc ccattaggta gctgtagcgt ttttggctcc gtagatcaat ataacgtagt
     7261 aagtgctcta cgagggacag aaacacttgc agacccctca aatatgttgg caataattat
     7321 tgctgataaa ttaaaaagaa aagaagaaaa taataccata cctatccaca tggctactac
     7381 tgctagggta ataagagcac aaaattttgt aggtaaaggt ttatattcac attttggctt
     7441 atattgtatg gtttcatctg gtatagatac agggtcttac acttgtgaaa aaatgttgtt
     7501 agaaaagcac ttaaactatt ataaagatat attaagtgaa atagaaaatg ttcgtttctc
     7561 tattattcta cgcaaaagaa acggatacaa agataatgac ggatttttcg acagaatggt
     7621 tgaaactatc aaacttattt ttcctaatat agagttatca attcataatg atgatgttga
     7681 taataattat tataaaggta tcaatttcaa attatcggtc aaacaaggaa atgaaaccgt
     7741 tgaaatagtt gacggtggat ttgttgactg gacttatcaa atgcttggaa ataaaagaga
     7801 acgctgtttg ataagtggta ttggcttaga aagatttctt gtagctgttt cataaaagga
     7861 gaagaaaaat ggaacttata gagtggaatt atgcttatat taccgattta gttgagtttg
     7921 cgaatgataa agaaattgca aagaatcttc gtgacaactt cccccaccct tatagggagc
     7981 aaaacgctag agattttgtt agtttttgtt tggcaacttc agatgttaaa caacttagct
     8041 atgctatttt ttatcaagaa agggctattg gaagtatcag cctaacattt gaagaagata
     8101 cctctattaa taaaaatgct gaattaggtt actggcttgc taggaactat tgaggcaaag
     8161 ggatagcaac aaatgcagta aaagaaatat gcaaaattgc ctttgaaaaa tacaacctta
     8221 acaaaattca tgctaatgta tattcctaca atagagagtc aagtaaagta ttggaaaaat
     8281 gtggctttaa gattgaagaa tactgtcaca attcataata aagaatagaa acatgattga
     8341 ttgccatgta tatagtttaa ttcgaccgca atagcattta ttagaattaa cctacttttt
     8401 aataacagaa taagtttttc ccctctatta atttcttatg catctttgta tttttatgaa
     8461 aagctagcca atgcatattt ccatacatca atatggtggt ggcttacaac caatataaat
     8521 taaatacgtt ttaaagaata cacatttttg ccctataggc agagtgtgta tttttttctc
     8581 ttttttttga aatttatcga agatttaacg ccctcccacc gtgataggag taagcaaggt
     8641 tatttaactc cttgcgatgg aaagagggtg aaatcttatg gttgatgaaa agacaattga
     8701 acatcaattc gacagtttct gtaaaacagt tttgcgtaac tatgctagag atatttatga
     8761 cgaaaataaa cgcagaaatg attatttggt atctctcgaa tctttgtcac ttgcagaatt
     8821 aagtaaattg agtattttag atgattatga ttctaactac atctgtatgg tttcttacga
     8881 ctacaacata cgaattgaag atgtattaat ggcgcaagca atcggaaaac ttacaaaaag
     8941 aaaacaagat ataattctac tttcattctt tttcaacatg acaaatgctg acatagcaac
     9001 attgatggat ttagcagaaa ataccataca ttatcacaaa acaaatgcac taaaagagtt
     9061 gaaagaactc atgcaggaac attgaaatga aacctactaa agaagtatta ccttttacaa
     9121 ttattttact tgctgtacat ggcgatgtaa atgcaataaa cgtaatactt aaacattttg
     9181 aacactatat cattcgtctt tcacagaaaa ctttatttga tgaatacgga aatccctata
     9241 ttcatgtaga agaagaaaca aagcgaatgc taggaacaaa actaatcact gctattttga
     9301 gatttaattt gtcttaatct cgccctctct ccatgtatca agctatttgg tacatggaga
     9361 atcactaatt atttgtctat aaaagcccac aagctattgt gattttttat aggcaaatca
     9421 atgccgactg ttctttgaca actgaataaa gtagatagat acgtttgtga tacagatagc
     9481 caacaaatac tatacgccat gaccttaatc aagagagcta ctatatagtg atttgtgaat
     9541 aacctttgga acggttgttt tgccgtaacc tgtaccacag tataatgata cacctgtatg
     9601 acacggttct gtccataaga atgggattgg ttgaaatacc aatggagctt atcaaagcca
     9661 tctatctact tctgaactac gaacatagaa aggagtgata cattatatga acaatactga
     9721 tgtacctatt tgggaaaaat ataccttgac gattgaagaa gcgtcaaaat actttcgtat
     9781 tggagagaaa aaattacgta aacgtgctga tgaaaacctt gattctggct gggtcattat
     9841 gaatagcaat cgcattcaaa taaagagaaa acaatttgag aaaatcgttg atacacttga
     9901 cgttatctaa tgaaattgag ccttatatgt tataatattc atatgacgta tcaagctcaa
     9961 ttcggttatt gagaggagct tcttatcatg tcaactgaaa aaagacgaga taataaagat
    10021 agaattttaa gaactggaga gagccagaga aaagatggaa gatacgcata taagtatgta
    10081 tattcatttg gtaaaccaca atttgtttac tcttggaaac ttgtacctac tgataaaccc
    10141 ccaaagggaa aacgtgatga tatatcatta agggataagg aaaaagcaat acaaaatgac
    10201 cttgatgata gcattgacac tattggtaag aaaatgacag tttgtcagtt atacgctaaa
    10261 aagaatggac taagaaagaa tatccgactt aacactaaaa aaggacgcca ttatcttatg
    10321 aagattctta acaaggagtg attctgtgaa gagatgtatt gtagtagtgg aatagtcaaa
    10381 aacataatat atattaaagg agagatttaa atatgactat tccaagttca aataaggtat
    10441 atccaagaag taatgattat caaactgtat atcttaaaaa tgtaataaca agggaaaata
    10501 tagaagttgg agattacaca atatataatg acttttataa tgacccaaga gattttgaga
    10561 aaaacaatgt attgtatcat taccctataa acaatgataa attaataatt ggtaagtttt
    10621 gctcaatagc atgtaatgca aaatttctaa tgactagtgg aaatcactca atgaaatcaa
    10681 aatccacata tacttttccc atcttttatg aagaatggaa actcgatatc aaccatataa
    10741 cggacgcttg ggacaataag ggtaacatta taattggaaa tgatgtgtgg ataggttatg
    10801 attctataat tatgtcaggt gtaaatattg gtgatggtgc aattattgga acaagagcag
    10861 tagttactaa tgacgttcca ccgtattcta ttgttggagg agtacctgca aaaattataa
    10921 aaaagagatt taataatgat acaatttcaa aattattaga aattaaatgg tgggattggc
    10981 catataaaaa aattcaatca aacattaagc atattcaatc aggaaatatt gataaattag
    11041 tttaatattt tataatttat ttatattaaa ctttacttta ataatcattt tataagagct
    11101 ttttcaaaat ttgtatatta ttttaatata tataaattta atac
//
